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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000540-TA|BGIBMGA000540-PA|IPR000195|RabGAP/TBC
         (894 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VYY9 Cluster: CG11727-PA, isoform A; n=8; Endopterygo...   773   0.0  
UniRef50_Q96CN4 Cluster: EVI5-like protein; n=21; Eumetazoa|Rep:...   530   e-149
UniRef50_Q4RZR5 Cluster: Chromosome 18 SCAF14786, whole genome s...   492   e-137
UniRef50_O60447 Cluster: Ecotropic viral integration site 5 prot...   448   e-124
UniRef50_UPI0000E4947B Cluster: PREDICTED: similar to ecotropic ...   429   e-118
UniRef50_UPI0000F1D57B Cluster: PREDICTED: similar to ecotropic ...   277   1e-72
UniRef50_Q9Y3P9 Cluster: Rab GTPase-activating protein 1; n=95; ...   251   6e-65
UniRef50_A7SQA7 Cluster: Predicted protein; n=1; Nematostella ve...   248   4e-64
UniRef50_A0MJ37 Cluster: P21; n=11; Caenorhabditis|Rep: P21 - Ca...   245   5e-63
UniRef50_UPI00015B4BF6 Cluster: PREDICTED: similar to rab6 gtpas...   239   2e-61
UniRef50_UPI0000DB6E1D Cluster: PREDICTED: similar to CG7112-PA,...   239   2e-61
UniRef50_Q967F6 Cluster: Putative uncharacterized protein; n=4; ...   230   1e-58
UniRef50_Q5K9R8 Cluster: Putative uncharacterized protein; n=1; ...   221   9e-56
UniRef50_Q8MT33 Cluster: RE63030p; n=8; Diptera|Rep: RE63030p - ...   220   1e-55
UniRef50_Q4P8R3 Cluster: Putative uncharacterized protein; n=1; ...   216   2e-54
UniRef50_Q5BW46 Cluster: SJCHGC05536 protein; n=1; Schistosoma j...   196   2e-48
UniRef50_O81347 Cluster: Plant adhesion molecule 1; n=11; Magnol...   188   6e-46
UniRef50_Q6C199 Cluster: Similar to tr|Q12344 Saccharomyces cere...   178   6e-43
UniRef50_Q38A97 Cluster: GTPase activating protein, putative; n=...   177   8e-43
UniRef50_Q5CR60 Cluster: TBC domain containing protein; n=2; Cry...   171   5e-41
UniRef50_Q19101 Cluster: Putative uncharacterized protein F01G12...   170   1e-40
UniRef50_Q9VNG9 Cluster: CG1093-PA, isoform A; n=8; Diptera|Rep:...   167   1e-39
UniRef50_Q86TI0 Cluster: TBC1 domain family member 1; n=33; Eute...   165   5e-39
UniRef50_Q6CR16 Cluster: Similar to sgd|S0006170 Saccharomyces c...   163   1e-38
UniRef50_O60343 Cluster: TBC1 domain family member 4; n=21; Eute...   163   1e-38
UniRef50_O97790 Cluster: TBC1 domain family member 1; n=4; Euthe...   163   1e-38
UniRef50_A5DNI2 Cluster: Putative uncharacterized protein; n=2; ...   163   2e-38
UniRef50_UPI0000F1EF08 Cluster: PREDICTED: similar to TBC1 domai...   163   3e-38
UniRef50_A3LZ48 Cluster: Predicted protein; n=2; Saccharomycetac...   160   1e-37
UniRef50_Q3TAQ5 Cluster: Activated spleen cDNA, RIKEN full-lengt...   159   2e-37
UniRef50_Q6CEY1 Cluster: Similarities with tr|AAH43775 Xenopus l...   159   2e-37
UniRef50_A5DY91 Cluster: Putative uncharacterized protein; n=1; ...   159   2e-37
UniRef50_Q0U1N8 Cluster: Putative uncharacterized protein; n=1; ...   159   3e-37
UniRef50_Q54KE5 Cluster: Putative uncharacterized protein; n=1; ...   158   7e-37
UniRef50_UPI00015B48C3 Cluster: PREDICTED: similar to Pollux pro...   157   2e-36
UniRef50_UPI0000519F7A Cluster: PREDICTED: similar to pollux CG1...   155   7e-36
UniRef50_UPI0000660373 Cluster: TBC1 domain family member 1.; n=...   154   1e-35
UniRef50_Q174R1 Cluster: Rab6 gtpase activating protein, gapcena...   153   2e-35
UniRef50_A5AB01 Cluster: Function: GAPCenA is a GTPase activatin...   153   2e-35
UniRef50_Q4Q0F3 Cluster: Rab-like GTPase activating protein, put...   152   5e-35
UniRef50_Q9P4Y9 Cluster: Putative uncharacterized protein B11B22...   151   1e-34
UniRef50_A4R5D7 Cluster: Putative uncharacterized protein; n=1; ...   150   1e-34
UniRef50_Q3UWI2 Cluster: 15 days embryo male testis cDNA, RIKEN ...   149   2e-34
UniRef50_A7TDN1 Cluster: Putative uncharacterized protein; n=1; ...   149   3e-34
UniRef50_Q755I4 Cluster: GTPase-activating protein GYP5; n=1; Er...   149   3e-34
UniRef50_A5K2X7 Cluster: TBC domain containing protein; n=1; Pla...   145   4e-33
UniRef50_Q7S9U4 Cluster: Putative uncharacterized protein NCU063...   142   4e-32
UniRef50_Q5VSE2 Cluster: Novel protein; n=6; Euteleostomi|Rep: N...   141   7e-32
UniRef50_Q86AV7 Cluster: Similar to Dictyostelium discoideum (Sl...   141   7e-32
UniRef50_Q12344 Cluster: GTPase-activating protein GYP5; n=3; Sa...   141   9e-32
UniRef50_Q7RNT0 Cluster: Plant adhesion molecule 1-related; n=2;...   140   2e-31
UniRef50_A2QJ75 Cluster: Complex: human GAPCenA interacts with R...   138   6e-31
UniRef50_Q4SF41 Cluster: Chromosome 1 SCAF14609, whole genome sh...   138   8e-31
UniRef50_Q9Y1V8 Cluster: HrPET-1; n=1; Halocynthia roretzi|Rep: ...   138   8e-31
UniRef50_A7S777 Cluster: Predicted protein; n=1; Nematostella ve...   138   8e-31
UniRef50_Q92738 Cluster: USP6 N-terminal-like protein; n=34; Eum...   136   2e-30
UniRef50_A6SIN1 Cluster: Putative uncharacterized protein; n=4; ...   135   4e-30
UniRef50_Q54YL8 Cluster: Putative uncharacterized protein; n=1; ...   135   6e-30
UniRef50_Q4DHN9 Cluster: Rab6 GTPase activating protein, putativ...   134   8e-30
UniRef50_Q6FSG3 Cluster: Candida glabrata strain CBS138 chromoso...   134   1e-29
UniRef50_Q5ZMK6 Cluster: Putative uncharacterized protein; n=12;...   130   2e-28
UniRef50_Q54SQ5 Cluster: Putative uncharacterized protein; n=1; ...   130   2e-28
UniRef50_Q8IV04 Cluster: Carabin; n=12; Eutheria|Rep: Carabin - ...   130   2e-28
UniRef50_Q245C4 Cluster: TBC domain containing protein; n=1; Tet...   129   4e-28
UniRef50_Q7RUP0 Cluster: Putative uncharacterized protein B11B22...   128   5e-28
UniRef50_Q9BXI6 Cluster: TBC1 domain family member 10A; n=32; Co...   128   9e-28
UniRef50_UPI000054717C Cluster: PREDICTED: similar to TBC1 domai...   126   4e-27
UniRef50_Q4Q0F2 Cluster: Rab-like GTPase activating protein, put...   124   1e-26
UniRef50_Q553Q2 Cluster: Putative uncharacterized protein; n=1; ...   122   4e-26
UniRef50_Q54WP7 Cluster: Putative uncharacterized protein; n=1; ...   122   4e-26
UniRef50_UPI000065EE1A Cluster: TBC1 domain family, member 3C (T...   122   6e-26
UniRef50_Q019L3 Cluster: Predicted GTPase activator NB4S/EVI5 (C...   122   6e-26
UniRef50_Q16XR6 Cluster: Ecotropic viral integration site; n=4; ...   121   8e-26
UniRef50_UPI0000ECBE92 Cluster: EVI5-like protein (Ecotropic vir...   120   1e-25
UniRef50_Q9VGL8 Cluster: CG5344-PA, isoform A; n=5; Endopterygot...   120   1e-25
UniRef50_Q0UL58 Cluster: Putative uncharacterized protein; n=2; ...   120   2e-25
UniRef50_Q4SDZ5 Cluster: Chromosome 13 SCAF14627, whole genome s...   119   3e-25
UniRef50_UPI00015B5223 Cluster: PREDICTED: similar to ecotropic ...   117   1e-24
UniRef50_Q10496 Cluster: Uncharacterized protein C26F1.09; n=1; ...   117   2e-24
UniRef50_A1Z9K4 Cluster: CG8085-PA, isoform A; n=6; Sophophora|R...   116   2e-24
UniRef50_UPI00015614CA Cluster: PREDICTED: hypothetical protein;...   116   3e-24
UniRef50_A7SA57 Cluster: Predicted protein; n=7; Eumetazoa|Rep: ...   116   3e-24
UniRef50_Q4DFJ7 Cluster: Rab-like GTPase activating protein, put...   116   4e-24
UniRef50_Q4KMP7 Cluster: TBC1 domain family member 10B; n=23; Th...   116   4e-24
UniRef50_Q9U2D8 Cluster: Putative uncharacterized protein; n=4; ...   115   7e-24
UniRef50_Q7RN69 Cluster: Homo sapiens dJ846D11.1, putative; n=4;...   115   7e-24
UniRef50_Q8SU09 Cluster: Similarity to HYPOTHETICAL TRANSMEMBRAN...   114   1e-23
UniRef50_UPI0000F1DA62 Cluster: PREDICTED: hypothetical protein;...   113   2e-23
UniRef50_A6RG76 Cluster: Putative uncharacterized protein; n=1; ...   113   3e-23
UniRef50_A7SQE4 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ...   111   8e-23
UniRef50_UPI0000E475AE Cluster: PREDICTED: similar to mKIAA1108 ...   110   2e-22
UniRef50_UPI00015B5228 Cluster: PREDICTED: similar to gh regulat...   109   2e-22
UniRef50_A7AST0 Cluster: TBC domain containing protein; n=1; Bab...   109   2e-22
UniRef50_Q8I379 Cluster: Putative uncharacterized protein PFI034...   109   3e-22
UniRef50_Q7PPV8 Cluster: ENSANGP00000014519; n=5; Coelomata|Rep:...   109   3e-22
UniRef50_A5K6E2 Cluster: TBC domain containing protein; n=2; Pla...   109   3e-22
UniRef50_UPI00015B478A Cluster: PREDICTED: similar to MGC155085 ...   109   4e-22
UniRef50_A1CI02 Cluster: GTPase activating protein (Gyp5), putat...   109   4e-22
UniRef50_Q4P413 Cluster: Putative uncharacterized protein; n=1; ...   107   1e-21
UniRef50_UPI000155D1B1 Cluster: PREDICTED: similar to TBC1 (tre-...   107   1e-21
UniRef50_O44873 Cluster: Putative uncharacterized protein; n=2; ...   107   1e-21
UniRef50_Q38A99 Cluster: GTPase activating protein, putative; n=...   107   2e-21
UniRef50_UPI00005A12CF Cluster: PREDICTED: similar to USP6 N-ter...   105   5e-21
UniRef50_Q16V33 Cluster: Putative uncharacterized protein; n=1; ...   105   5e-21
UniRef50_Q9UPU7 Cluster: TBC1 domain family member 2B; n=36; Eum...   103   2e-20
UniRef50_UPI0000D558F9 Cluster: PREDICTED: similar to TBC1 domai...   103   2e-20
UniRef50_O60347 Cluster: TBC1 domain family member 12; n=11; Eum...   103   3e-20
UniRef50_Q6CG19 Cluster: Similar to sp|P53258 Saccharomyces cere...   102   4e-20
UniRef50_Q6PBU5 Cluster: Growth hormone-regulated TBC protein 1;...   101   9e-20
UniRef50_O43048 Cluster: GTPase activating protein; n=2; Schizos...   101   1e-19
UniRef50_A3GF95 Cluster: GTPase activating protein; n=5; Sacchar...   101   1e-19
UniRef50_Q4T9Z2 Cluster: Chromosome undetermined SCAF7482, whole...   100   2e-19
UniRef50_A0DZJ7 Cluster: Chromosome undetermined scaffold_70, wh...   100   2e-19
UniRef50_Q55TD4 Cluster: Putative uncharacterized protein; n=2; ...   100   3e-19
UniRef50_Q4PG28 Cluster: Putative uncharacterized protein; n=1; ...   100   3e-19
UniRef50_A7TSB1 Cluster: Putative uncharacterized protein; n=1; ...   100   3e-19
UniRef50_A2EVI1 Cluster: TBC domain containing protein; n=1; Tri...    99   5e-19
UniRef50_UPI0000588ED3 Cluster: PREDICTED: hypothetical protein ...    99   6e-19
UniRef50_Q76LY3 Cluster: KIAA1322; n=22; Deuterostomia|Rep: KIAA...    99   6e-19
UniRef50_Q4RGZ6 Cluster: Chromosome undetermined SCAF15081, whol...    98   8e-19
UniRef50_Q23MA0 Cluster: TBC domain containing protein; n=2; Alv...    98   8e-19
UniRef50_UPI0000E46298 Cluster: PREDICTED: similar to mKIAA4104 ...    98   1e-18
UniRef50_A7AQU6 Cluster: RabGAP/TBC domain-containing protein, p...    98   1e-18
UniRef50_Q04322 Cluster: Uncharacterized protein YMR192W; n=2; S...    98   1e-18
UniRef50_Q96HU1 Cluster: RUN and TBC1 domain containing 3; n=34;...    97   2e-18
UniRef50_Q7Z709 Cluster: RUN and TBC1 domain-containing protein ...    97   2e-18
UniRef50_Q9P2M4 Cluster: TBC1 domain family member 14; n=29; Coe...    97   2e-18
UniRef50_Q1H5B2 Cluster: At3g07890; n=7; Magnoliophyta|Rep: At3g...    96   3e-18
UniRef50_Q9VP46 Cluster: CG7324-PA; n=3; Diptera|Rep: CG7324-PA ...    96   3e-18
UniRef50_Q553U1 Cluster: Putative uncharacterized protein; n=1; ...    96   4e-18
UniRef50_Q54H32 Cluster: Putative uncharacterized protein; n=1; ...    96   4e-18
UniRef50_UPI00004286DB Cluster: growth hormone regulated TBC pro...    95   6e-18
UniRef50_Q9VEY4 Cluster: CG5916-PA; n=5; Endopterygota|Rep: CG59...    95   6e-18
UniRef50_Q5TC63 Cluster: Growth hormone-regulated TBC protein 1;...    95   6e-18
UniRef50_A7ARE0 Cluster: GTPase activator protein, putative; n=1...    95   8e-18
UniRef50_Q2H4R6 Cluster: Putative uncharacterized protein; n=3; ...    95   1e-17
UniRef50_UPI000051A1A7 Cluster: PREDICTED: similar to TBC1 domai...    94   1e-17
UniRef50_Q7RB90 Cluster: Plant adhesion molecule 1; n=4; Plasmod...    94   1e-17
UniRef50_Q54Z16 Cluster: Putative uncharacterized protein; n=1; ...    94   2e-17
UniRef50_Q5KAJ1 Cluster: Mic1-like protein, putative; n=1; Filob...    94   2e-17
UniRef50_Q9Z1A9 Cluster: TBC1 domain family member 8; n=22; Amni...    93   2e-17
UniRef50_A0DWA3 Cluster: Chromosome undetermined scaffold_67, wh...    93   3e-17
UniRef50_P53258 Cluster: GTPase-activating protein GYP2; n=5; Sa...    93   3e-17
UniRef50_Q23419 Cluster: Putative uncharacterized protein; n=2; ...    93   4e-17
UniRef50_A2EQP1 Cluster: TBC domain containing protein; n=2; Tri...    93   4e-17
UniRef50_Q7RRJ2 Cluster: Putative uncharacterized protein PY0072...    92   5e-17
UniRef50_Q4UCH6 Cluster: Putative uncharacterized protein; n=2; ...    92   5e-17
UniRef50_O95759 Cluster: TBC1 domain family member 8; n=45; Eute...    92   5e-17
UniRef50_UPI000150A407 Cluster: TBC domain containing protein; n...    92   7e-17
UniRef50_UPI00006CB764 Cluster: TBC domain containing protein; n...    92   7e-17
UniRef50_UPI000049837E Cluster: Rab GTPase activating protein; n...    91   9e-17
UniRef50_Q54UM5 Cluster: Putative uncharacterized protein; n=1; ...    91   9e-17
UniRef50_UPI000065F402 Cluster: Homolog of Homo sapiens "TBC1 do...    91   1e-16
UniRef50_Q93316 Cluster: Putative uncharacterized protein; n=2; ...    91   2e-16
UniRef50_Q55E78 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-16
UniRef50_A7REP1 Cluster: Predicted protein; n=1; Nematostella ve...    90   3e-16
UniRef50_Q09830 Cluster: Uncharacterized protein C4G8.04; n=1; S...    90   3e-16
UniRef50_Q6ZT07 Cluster: TBC1 domain family member 9; n=76; Deut...    90   3e-16
UniRef50_Q5CZG9 Cluster: TBS1 protein; n=2; Paramecium tetraurel...    89   7e-16
UniRef50_A4RBP4 Cluster: Putative uncharacterized protein; n=2; ...    89   7e-16
UniRef50_Q21928 Cluster: Putative uncharacterized protein R11B5....    88   1e-15
UniRef50_Q4RWK8 Cluster: Chromosome 3 SCAF14987, whole genome sh...    87   2e-15
UniRef50_Q4RTM1 Cluster: Chromosome 2 SCAF14997, whole genome sh...    87   2e-15
UniRef50_Q7YYL8 Cluster: GTPase activator protein, possible; n=3...    87   2e-15
UniRef50_Q7R5W8 Cluster: GLP_81_109382_107820; n=1; Giardia lamb...    87   2e-15
UniRef50_UPI0000F1EDBF Cluster: PREDICTED: hypothetical protein;...    87   3e-15
UniRef50_Q5KGA6 Cluster: GTPase activating protein, putative; n=...    87   3e-15
UniRef50_Q8IZP1 Cluster: TBC1 domain family member 3; n=79; Cata...    87   3e-15
UniRef50_UPI0000DB6E56 Cluster: PREDICTED: similar to CG7324-PA;...    86   3e-15
UniRef50_Q4SM04 Cluster: Chromosome 13 SCAF14555, whole genome s...    86   5e-15
UniRef50_Q4DET3 Cluster: GTPase activator protein, putative; n=2...    86   5e-15
UniRef50_A2EN43 Cluster: TBC domain containing protein; n=1; Tri...    86   5e-15
UniRef50_UPI00015B49B5 Cluster: PREDICTED: similar to TBC1 domai...    85   6e-15
UniRef50_UPI0000DBF1CE Cluster: similar to FLJ20298 protein isof...    85   8e-15
UniRef50_Q4SJ91 Cluster: Chromosome 4 SCAF14575, whole genome sh...    85   8e-15
UniRef50_A0CUC2 Cluster: Chromosome undetermined scaffold_28, wh...    85   8e-15
UniRef50_UPI0000E247DD Cluster: PREDICTED: TBC1 domain family, m...    85   1e-14
UniRef50_UPI00005A604F Cluster: PREDICTED: similar to USP6 N-ter...    85   1e-14
UniRef50_Q5CLC5 Cluster: GTPase activator protein; n=3; Cryptosp...    84   1e-14
UniRef50_A0DIR4 Cluster: Chromosome undetermined scaffold_52, wh...    84   1e-14
UniRef50_Q873F9 Cluster: Putative uncharacterized protein B10C3....    84   1e-14
UniRef50_A5E5S6 Cluster: Putative uncharacterized protein; n=1; ...    84   2e-14
UniRef50_UPI000065E779 Cluster: TBC1 domain family member 10A (E...    83   2e-14
UniRef50_A5KAZ5 Cluster: TBC domain containing protein; n=1; Pla...    83   2e-14
UniRef50_A4VDB7 Cluster: Putative uncharacterized protein; n=1; ...    83   2e-14
UniRef50_UPI00005A08B8 Cluster: PREDICTED: similar to USP6 N-ter...    83   3e-14
UniRef50_Q2GVF3 Cluster: Putative uncharacterized protein; n=1; ...    83   4e-14
UniRef50_O62462 Cluster: Putative uncharacterized protein; n=4; ...    82   6e-14
UniRef50_Q4CMS8 Cluster: Putative uncharacterized protein; n=2; ...    81   1e-13
UniRef50_Q0UN04 Cluster: Putative uncharacterized protein; n=1; ...    81   1e-13
UniRef50_UPI0000E4616F Cluster: PREDICTED: similar to mKIAA1055 ...    81   2e-13
UniRef50_A4HHG8 Cluster: GTPase activator protein, putative; n=3...    80   2e-13
UniRef50_UPI00006CA417 Cluster: TBC domain containing protein; n...    80   3e-13
UniRef50_Q4UF50 Cluster: GTPase activator, putative; n=3; Theile...    80   3e-13
UniRef50_A2DSN7 Cluster: TBC domain containing protein; n=1; Tri...    80   3e-13
UniRef50_A6RXA8 Cluster: Putative uncharacterized protein; n=2; ...    80   3e-13
UniRef50_Q12317 Cluster: GTPase-activating protein MSB4; n=2; Sa...    80   3e-13
UniRef50_Q4S8R1 Cluster: Chromosome 7 SCAF14703, whole genome sh...    79   4e-13
UniRef50_A0D1G2 Cluster: Chromosome undetermined scaffold_34, wh...    79   4e-13
UniRef50_Q0DSW7 Cluster: Os03g0283800 protein; n=7; Magnoliophyt...    79   5e-13
UniRef50_A2FGC2 Cluster: TBC domain containing protein; n=1; Tri...    79   5e-13
UniRef50_Q4PEJ4 Cluster: Putative uncharacterized protein; n=1; ...    79   5e-13
UniRef50_Q22P21 Cluster: TBC domain containing protein; n=1; Tet...    79   7e-13
UniRef50_A0EBU5 Cluster: Chromosome undetermined scaffold_88, wh...    79   7e-13
UniRef50_A0CVA1 Cluster: Chromosome undetermined scaffold_29, wh...    79   7e-13
UniRef50_Q5KC17 Cluster: Rab GTPase activator, putative; n=2; Fi...    78   9e-13
UniRef50_A3LRK5 Cluster: Predicted protein; n=3; Saccharomycetac...    78   9e-13
UniRef50_Q4T9M9 Cluster: Chromosome undetermined SCAF7533, whole...    78   1e-12
UniRef50_A7AUV6 Cluster: TBC domain containing protein; n=1; Bab...    78   1e-12
UniRef50_Q4P6P1 Cluster: Putative uncharacterized protein; n=1; ...    78   1e-12
UniRef50_A2EC67 Cluster: TBC domain containing protein; n=1; Tri...    77   2e-12
UniRef50_UPI00005A1247 Cluster: PREDICTED: similar to USP6 N-ter...    77   2e-12
UniRef50_Q94222 Cluster: Putative uncharacterized protein; n=3; ...    75   6e-12
UniRef50_Q5CTF9 Cluster: Tbc domain-containing protein; n=2; Cry...    75   6e-12
UniRef50_Q9BYX2 Cluster: TBC1 domain family member 2; n=36; Eute...    75   6e-12
UniRef50_A2ELI1 Cluster: TBC domain containing protein; n=1; Tri...    75   9e-12
UniRef50_Q6CGJ8 Cluster: Similar to DEHA0D17149g Debaryomyces ha...    75   9e-12
UniRef50_UPI0000F33224 Cluster: TBC1 domain family member 1 (Lyn...    75   1e-11
UniRef50_Q9Y7J5 Cluster: GTPase activating protein; n=1; Schizos...    75   1e-11
UniRef50_Q6CDM5 Cluster: Similar to sp|P48566 Saccharomyces cere...    74   2e-11
UniRef50_O94711 Cluster: GTPase activating protein Gyp2; n=1; Sc...    74   2e-11
UniRef50_A6QZT7 Cluster: Putative uncharacterized protein; n=1; ...    74   2e-11
UniRef50_Q09445 Cluster: Uncharacterized protein C04A2.1; n=2; C...    74   2e-11
UniRef50_A6QUK8 Cluster: Putative uncharacterized protein; n=1; ...    73   3e-11
UniRef50_UPI00005A4648 Cluster: PREDICTED: similar to USP6 N-ter...    73   3e-11
UniRef50_O96904 Cluster: Drainin; n=2; Dictyostelium discoideum|...    73   5e-11
UniRef50_Q5DGV1 Cluster: SJCHGC08537 protein; n=1; Schistosoma j...    72   8e-11
UniRef50_A0ECU1 Cluster: Chromosome undetermined scaffold_9, who...    72   8e-11
UniRef50_UPI0000498A13 Cluster: Rab GTPase activating protein; n...    71   1e-10
UniRef50_A7SUG8 Cluster: Predicted protein; n=2; Nematostella ve...    71   1e-10
UniRef50_A0D8F0 Cluster: Chromosome undetermined scaffold_41, wh...    71   1e-10
UniRef50_UPI0000ECC2F9 Cluster: TBC1 domain family member 2 (Pro...    71   2e-10
UniRef50_Q1EB21 Cluster: Putative uncharacterized protein; n=2; ...    70   2e-10
UniRef50_UPI00006CBFC6 Cluster: TBC domain containing protein; n...    70   3e-10
UniRef50_Q55EP9 Cluster: RabGAP/TBC domain-containing protein; n...    70   3e-10
UniRef50_Q6CXK6 Cluster: Similarities with sp|P48566 Saccharomyc...    70   3e-10
UniRef50_UPI000049A372 Cluster: Rab GTPase activating protein; n...    69   4e-10
UniRef50_Q9ZUT7 Cluster: Putative uncharacterized protein At2g37...    69   4e-10
UniRef50_A0CB10 Cluster: Chromosome undetermined scaffold_163, w...    69   4e-10
UniRef50_A4R2B1 Cluster: Putative uncharacterized protein; n=1; ...    69   4e-10
UniRef50_UPI0000F216EC Cluster: PREDICTED: hypothetical protein;...    69   6e-10
UniRef50_Q940C5 Cluster: AT3g55020/T15C9_20; n=11; Magnoliophyta...    69   7e-10
UniRef50_A2EMR6 Cluster: Viral A-type inclusion protein, putativ...    68   1e-09
UniRef50_A0CZM7 Cluster: Chromosome undetermined scaffold_32, wh...    68   1e-09
UniRef50_UPI00005A2F5A Cluster: PREDICTED: similar to USP6 N-ter...    68   1e-09
UniRef50_UPI00006607B9 Cluster: Homolog of Homo sapiens "Plectin...    68   1e-09
UniRef50_A0DIR7 Cluster: Chromosome undetermined scaffold_52, wh...    68   1e-09
UniRef50_UPI00006CB3B2 Cluster: TBC domain containing protein; n...    67   2e-09
UniRef50_UPI00005A05A7 Cluster: PREDICTED: similar to USP6 N-ter...    67   2e-09
UniRef50_A0E2P6 Cluster: Chromosome undetermined scaffold_75, wh...    67   2e-09
UniRef50_Q8NJL3 Cluster: Putative uncharacterized protein AfA12H...    67   2e-09
UniRef50_UPI000150A2A4 Cluster: QXW lectin repeat family protein...    67   2e-09
UniRef50_Q015P5 Cluster: Predicted GTPase activator NB4S/EVI5 (C...    67   2e-09
UniRef50_Q54SA3 Cluster: Putative uncharacterized protein; n=1; ...    67   2e-09
UniRef50_A2DJG6 Cluster: TBC domain containing protein; n=1; Tri...    67   2e-09
UniRef50_A0DLN3 Cluster: Chromosome undetermined scaffold_556, w...    67   2e-09
UniRef50_A0CZT6 Cluster: Chromosome undetermined scaffold_32, wh...    67   2e-09
UniRef50_UPI000023D00A Cluster: hypothetical protein FG01414.1; ...    66   3e-09
UniRef50_Q552F5 Cluster: RabGAP/TBC domain-containing protein; n...    66   5e-09
UniRef50_Q23QD2 Cluster: TBC domain containing protein; n=1; Tet...    66   5e-09
UniRef50_A0CPP1 Cluster: Chromosome undetermined scaffold_23, wh...    66   5e-09
UniRef50_UPI0000D56108 Cluster: PREDICTED: similar to CG18304-PA...    65   7e-09
UniRef50_Q22DV1 Cluster: TBC domain containing protein; n=1; Tet...    65   7e-09
UniRef50_A7TMR1 Cluster: Putative uncharacterized protein; n=1; ...    65   7e-09
UniRef50_A1CU07 Cluster: TBC domain protein, putative; n=6; Tric...    65   7e-09
UniRef50_A4R5R2 Cluster: Putative uncharacterized protein; n=1; ...    65   9e-09
UniRef50_Q4S5H4 Cluster: Chromosome 3 SCAF14730, whole genome sh...    64   1e-08
UniRef50_Q22H03 Cluster: TBC domain containing protein; n=1; Tet...    64   1e-08
UniRef50_A0ECU5 Cluster: Chromosome undetermined scaffold_9, who...    64   1e-08
UniRef50_A0BIT5 Cluster: Chromosome undetermined scaffold_11, wh...    64   1e-08
UniRef50_Q14980 Cluster: Nuclear mitotic apparatus protein 1; n=...    64   1e-08
UniRef50_UPI0000D9E1CB Cluster: PREDICTED: similar to USP6 N-ter...    64   2e-08
UniRef50_UPI0000499D90 Cluster: Rab GTPase activating protein; n...    64   2e-08
UniRef50_A2FD36 Cluster: Viral A-type inclusion protein, putativ...    64   2e-08
UniRef50_Q8TXA4 Cluster: Uncharacterized protein; n=2; cellular ...    64   2e-08
UniRef50_Q4SU35 Cluster: Chromosome undetermined SCAF14025, whol...    64   2e-08
UniRef50_Q7PVQ7 Cluster: ENSANGP00000023159; n=1; Anopheles gamb...    64   2e-08
UniRef50_Q4DQS9 Cluster: Putative uncharacterized protein; n=2; ...    64   2e-08
UniRef50_A4HCH0 Cluster: Putative uncharacterized protein; n=1; ...    64   2e-08
UniRef50_P48566 Cluster: GTPase-activating protein GYP3; n=3; Sa...    64   2e-08
UniRef50_UPI00006CC47C Cluster: TBC domain containing protein; n...    63   3e-08
UniRef50_Q4ST41 Cluster: Chromosome 18 SCAF14304, whole genome s...    63   3e-08
UniRef50_A2FQ07 Cluster: Viral A-type inclusion protein, putativ...    63   3e-08
UniRef50_A0CDG4 Cluster: Chromosome undetermined scaffold_17, wh...    63   3e-08
UniRef50_UPI0000F21218 Cluster: PREDICTED: similar to RabGAP/TBC...    63   4e-08
UniRef50_UPI00006A154D Cluster: Centrosomal protein 2 (Centrosom...    63   4e-08
UniRef50_A3H7Q7 Cluster: Chromosome segregation ATPases-like; n=...    63   4e-08
UniRef50_Q4RQ56 Cluster: Chromosome 17 SCAF15006, whole genome s...    62   5e-08
UniRef50_Q55MA7 Cluster: Putative uncharacterized protein; n=2; ...    62   5e-08
UniRef50_Q0UF35 Cluster: Putative uncharacterized protein; n=1; ...    62   6e-08
UniRef50_UPI00005A2E10 Cluster: PREDICTED: similar to USP6 N-ter...    62   9e-08
UniRef50_Q1HTS1 Cluster: S1L; n=1; Squirrelpox virus|Rep: S1L - ...    62   9e-08
UniRef50_A0EG40 Cluster: Chromosome undetermined scaffold_94, wh...    62   9e-08
UniRef50_Q54IZ7 Cluster: Putative uncharacterized protein; n=1; ...    61   1e-07
UniRef50_A2DGN0 Cluster: Viral A-type inclusion protein, putativ...    61   1e-07
UniRef50_A0DQH1 Cluster: Chromosome undetermined scaffold_6, who...    61   1e-07
UniRef50_A7TLC9 Cluster: Putative uncharacterized protein; n=1; ...    61   1e-07
UniRef50_UPI000155631D Cluster: PREDICTED: hypothetical protein;...    61   1e-07
UniRef50_UPI0000D9E278 Cluster: PREDICTED: similar to USP6 N-ter...    61   1e-07
UniRef50_A6C0X8 Cluster: Putative uncharacterized protein; n=1; ...    61   1e-07
UniRef50_A2EN31 Cluster: Viral A-type inclusion protein, putativ...    61   1e-07
UniRef50_P35749 Cluster: Myosin-11; n=123; Eukaryota|Rep: Myosin...    61   1e-07
UniRef50_UPI000049867C Cluster: hypothetical protein 219.t00015;...    60   2e-07
UniRef50_UPI000023E7AE Cluster: hypothetical protein FG05994.1; ...    60   2e-07
UniRef50_Q4Z2E8 Cluster: Putative uncharacterized protein; n=4; ...    60   2e-07
UniRef50_A2DER5 Cluster: Putative uncharacterized protein; n=2; ...    60   2e-07
UniRef50_Q4T928 Cluster: Chromosome undetermined SCAF7646, whole...    60   3e-07
UniRef50_A1CDE3 Cluster: TBC domain protein, putative; n=8; Euro...    60   3e-07
UniRef50_UPI0000D5597D Cluster: PREDICTED: similar to CG5020-PA,...    60   3e-07
UniRef50_Q4QBL5 Cluster: Putative uncharacterized protein; n=3; ...    60   3e-07
UniRef50_A2DGV9 Cluster: Viral A-type inclusion protein, putativ...    60   3e-07
UniRef50_UPI0000F1EAEF Cluster: PREDICTED: hypothetical protein;...    59   5e-07
UniRef50_A0CX43 Cluster: Chromosome undetermined scaffold_3, who...    59   5e-07
UniRef50_Q6FM53 Cluster: Similar to sp|Q04322 Saccharomyces cere...    59   5e-07
UniRef50_Q1E200 Cluster: Putative uncharacterized protein; n=1; ...    59   5e-07
UniRef50_A7EK55 Cluster: Putative uncharacterized protein; n=1; ...    59   5e-07
UniRef50_Q14203 Cluster: Dynactin subunit 1; n=96; Euteleostomi|...    59   5e-07
UniRef50_Q24HK7 Cluster: Viral A-type inclusion protein repeat c...    59   6e-07
UniRef50_A0CJL1 Cluster: Chromosome undetermined scaffold_2, who...    59   6e-07
UniRef50_UPI0000D5750B Cluster: PREDICTED: similar to CG8274-PA;...    58   8e-07
UniRef50_Q6DEI1 Cluster: TATA element modulatory factor 1; n=4; ...    58   8e-07
UniRef50_Q014R9 Cluster: Cation-transporting ATPase; n=4; Eukary...    58   8e-07
UniRef50_Q32KE8 Cluster: RE58741p; n=3; Sophophora|Rep: RE58741p...    58   8e-07
UniRef50_Q234R7 Cluster: Viral A-type inclusion protein repeat c...    58   8e-07
UniRef50_Q22D80 Cluster: Putative uncharacterized protein; n=1; ...    58   8e-07
UniRef50_A5DLM2 Cluster: Putative uncharacterized protein; n=1; ...    58   8e-07
UniRef50_A4RAX3 Cluster: Putative uncharacterized protein; n=2; ...    58   8e-07
UniRef50_UPI00005A3562 Cluster: PREDICTED: similar to USP6 N-ter...    58   1e-06
UniRef50_Q4QCC9 Cluster: Putative uncharacterized protein; n=3; ...    58   1e-06
UniRef50_A2FHD4 Cluster: Trichohyalin, putative; n=1; Trichomona...    58   1e-06
UniRef50_UPI0000E254D5 Cluster: PREDICTED: plectin 1; n=3; Amnio...    58   1e-06
UniRef50_UPI00004991F6 Cluster: Rab GTPase activating protein; n...    58   1e-06
UniRef50_Q4RMN0 Cluster: Chromosome 10 SCAF15019, whole genome s...    58   1e-06
UniRef50_Q22RB5 Cluster: Putative uncharacterized protein; n=1; ...    58   1e-06
UniRef50_A2DNX6 Cluster: Viral A-type inclusion protein, putativ...    58   1e-06
UniRef50_A0D2T6 Cluster: Chromosome undetermined scaffold_35, wh...    58   1e-06
UniRef50_P06198 Cluster: Paramyosin; n=19; Bilateria|Rep: Paramy...    58   1e-06
UniRef50_UPI0000F1EA57 Cluster: PREDICTED: similar to ninein-lik...    57   2e-06
UniRef50_UPI0000DA32F1 Cluster: PREDICTED: similar to ciliary ro...    57   2e-06
UniRef50_Q6NW47 Cluster: Zgc:85975; n=2; Danio rerio|Rep: Zgc:85...    57   2e-06
UniRef50_Q382P4 Cluster: Putative uncharacterized protein; n=1; ...    57   2e-06
UniRef50_Q16IF0 Cluster: Condensin, SMC5-subunit, putative; n=1;...    57   2e-06
UniRef50_A2G5Q5 Cluster: Putative uncharacterized protein; n=1; ...    57   2e-06
UniRef50_A0EHN8 Cluster: Chromosome undetermined scaffold_97, wh...    57   2e-06
UniRef50_A0BMM9 Cluster: Chromosome undetermined scaffold_117, w...    57   2e-06
UniRef50_Q0UXP8 Cluster: Putative uncharacterized protein; n=1; ...    57   2e-06
UniRef50_Q0U2A3 Cluster: Putative uncharacterized protein; n=1; ...    57   2e-06
UniRef50_UPI00006CD2DD Cluster: Viral A-type inclusion protein r...    57   2e-06
UniRef50_Q4S6R6 Cluster: Chromosome undetermined SCAF14724, whol...    57   2e-06
UniRef50_A1IH01 Cluster: Golgin97; n=4; Danio rerio|Rep: Golgin9...    57   2e-06
UniRef50_A0YYA0 Cluster: Putative uncharacterized protein; n=2; ...    57   2e-06
UniRef50_Q9LTF8 Cluster: Similarity to GTPase activating protein...    57   2e-06
UniRef50_Q6BFQ1 Cluster: Rab-GAP domain-containing protein, puta...    57   2e-06
UniRef50_A2DD37 Cluster: Viral A-type inclusion protein, putativ...    57   2e-06
UniRef50_Q7Z2L3 Cluster: KIAA1749 protein; n=32; Tetrapoda|Rep: ...    57   2e-06
UniRef50_Q7S473 Cluster: Putative uncharacterized protein NCU024...    57   2e-06
UniRef50_Q2GVV3 Cluster: Putative uncharacterized protein; n=1; ...    57   2e-06
UniRef50_O94419 Cluster: GTPase activating protein; n=1; Schizos...    57   2e-06
UniRef50_A6SB40 Cluster: Putative uncharacterized protein; n=1; ...    57   2e-06
UniRef50_Q8MSS1 Cluster: Protein lava lamp; n=1; Drosophila mela...    57   2e-06
UniRef50_UPI0000E48979 Cluster: PREDICTED: similar to kinesin-re...    56   3e-06
UniRef50_UPI00006CCAA0 Cluster: conserved hypothetical protein; ...    56   3e-06
UniRef50_UPI00006CCA8D Cluster: hypothetical protein TTHERM_0028...    56   3e-06
UniRef50_Q82UT3 Cluster: ATP/GTP-binding site motif A (P-loop):A...    56   3e-06
UniRef50_Q57UD0 Cluster: Kinesin K39, putative; n=1; Trypanosoma...    56   3e-06
UniRef50_Q23PV9 Cluster: TBC domain containing protein; n=1; Tet...    56   3e-06
UniRef50_A2ESN0 Cluster: Viral A-type inclusion protein, putativ...    56   3e-06
UniRef50_UPI0000E490EC Cluster: PREDICTED: similar to coiled-coi...    56   4e-06
UniRef50_Q4T443 Cluster: Chromosome undetermined SCAF9830, whole...    56   4e-06
UniRef50_Q0DKA1 Cluster: Os05g0180400 protein; n=7; Oryza sativa...    56   4e-06
UniRef50_A7QNA8 Cluster: Chromosome chr2 scaffold_132, whole gen...    56   4e-06
UniRef50_Q9GKN4 Cluster: Mitosin; n=6; Laurasiatheria|Rep: Mitos...    56   4e-06
UniRef50_A2FSZ8 Cluster: Viral A-type inclusion protein, putativ...    56   4e-06
UniRef50_A2FQ08 Cluster: Viral A-type inclusion protein, putativ...    56   4e-06
UniRef50_A2EYA1 Cluster: Viral A-type inclusion protein, putativ...    56   4e-06
UniRef50_A2DKP8 Cluster: Viral A-type inclusion protein, putativ...    56   4e-06
UniRef50_Q9VJE5 Cluster: Restin homolog; n=4; Drosophila melanog...    56   4e-06
UniRef50_UPI00006CD0F6 Cluster: Protein kinase domain containing...    56   6e-06
UniRef50_Q4TI27 Cluster: Chromosome undetermined SCAF2445, whole...    56   6e-06
UniRef50_Q9FJ35 Cluster: Myosin heavy chain-like protein; n=2; A...    56   6e-06
UniRef50_Q4Q843 Cluster: Glycoprotein 96-92, putative; n=5; Leis...    56   6e-06
UniRef50_Q4E572 Cluster: Antigenic protein, putative; n=2; Trypa...    56   6e-06
UniRef50_A0E403 Cluster: Chromosome undetermined scaffold_77, wh...    56   6e-06
UniRef50_Q757G8 Cluster: AER045Cp; n=1; Eremothecium gossypii|Re...    56   6e-06
UniRef50_Q6C359 Cluster: Similar to DEHA0C09658g Debaryomyces ha...    56   6e-06
UniRef50_O75334 Cluster: Liprin-alpha-2; n=43; Euteleostomi|Rep:...    56   6e-06
UniRef50_UPI0000DB6CD6 Cluster: PREDICTED: similar to ornithine ...    55   7e-06
UniRef50_UPI00006A1EBC Cluster: Leucine-rich repeat-containing p...    55   7e-06
UniRef50_Q4TA61 Cluster: Chromosome undetermined SCAF7445, whole...    55   7e-06
UniRef50_Q4SSB9 Cluster: Chromosome undetermined SCAF14473, whol...    55   7e-06
UniRef50_A5D6T7 Cluster: Si:dkey-204a24.2 protein; n=5; Danio re...    55   7e-06
UniRef50_Q4DI03 Cluster: Basal body component, putative; n=2; Tr...    55   7e-06
UniRef50_Q4DH57 Cluster: Putative uncharacterized protein; n=2; ...    55   7e-06
UniRef50_Q6C1X8 Cluster: Similarities with wi|NCU02211.1 Neurosp...    55   7e-06
UniRef50_Q8N8E3 Cluster: Coiled-coil domain-containing protein 4...    55   7e-06
UniRef50_UPI0000E4990A Cluster: PREDICTED: hypothetical protein;...    55   1e-05
UniRef50_Q7Q3Y2 Cluster: ENSANGP00000010412; n=2; Culicidae|Rep:...    55   1e-05
UniRef50_Q25561 Cluster: Myosin II heavy chain; n=1; Naegleria f...    55   1e-05
UniRef50_A2DDX5 Cluster: Viral A-type inclusion protein, putativ...    55   1e-05
UniRef50_A2DDP2 Cluster: Viral A-type inclusion protein, putativ...    55   1e-05
UniRef50_A0DDB5 Cluster: Chromosome undetermined scaffold_46, wh...    55   1e-05
UniRef50_A0CPG2 Cluster: Chromosome undetermined scaffold_23, wh...    55   1e-05
UniRef50_A6S2A5 Cluster: Putative uncharacterized protein; n=2; ...    55   1e-05
UniRef50_UPI0000E4A11B Cluster: PREDICTED: hypothetical protein;...    54   1e-05
UniRef50_UPI00015A8049 Cluster: UPI00015A8049 related cluster; n...    54   1e-05
UniRef50_Q6X1Y7 Cluster: Effector protein B; n=6; Legionella pne...    54   1e-05
UniRef50_Q5RD65 Cluster: Putative uncharacterized protein DKFZp4...    54   1e-05
UniRef50_Q45WA6 Cluster: Rhoptry protein 14; n=1; Toxoplasma gon...    54   1e-05
UniRef50_A0EHS3 Cluster: Chromosome undetermined scaffold_97, wh...    54   1e-05
UniRef50_A0DWU7 Cluster: Chromosome undetermined scaffold_67, wh...    54   1e-05
UniRef50_UPI00006CE63C Cluster: hypothetical protein TTHERM_0070...    54   2e-05
UniRef50_UPI00006A0625 Cluster: TBC1 domain family member 14.; n...    54   2e-05
UniRef50_A6LRZ8 Cluster: Putative uncharacterized protein; n=1; ...    54   2e-05
UniRef50_Q9VYU0 Cluster: CG32662-PA; n=2; Drosophila melanogaste...    54   2e-05
UniRef50_Q7PXA5 Cluster: ENSANGP00000020914; n=2; Culicidae|Rep:...    54   2e-05
UniRef50_Q38C95 Cluster: Putative uncharacterized protein; n=1; ...    54   2e-05
UniRef50_A2FSV7 Cluster: Putative uncharacterized protein; n=1; ...    54   2e-05
UniRef50_A2DLG0 Cluster: Viral A-type inclusion protein, putativ...    54   2e-05
UniRef50_A0BXA6 Cluster: Chromosome undetermined scaffold_134, w...    54   2e-05
UniRef50_Q4WXF9 Cluster: Spindle-pole body protein (Pcp1), putat...    54   2e-05
UniRef50_P21249 Cluster: Major antigen; n=4; Onchocerca|Rep: Maj...    54   2e-05
UniRef50_UPI0001554812 Cluster: PREDICTED: similar to rootletin;...    54   2e-05
UniRef50_UPI0000F1E2B5 Cluster: PREDICTED: similar to pericentri...    54   2e-05
UniRef50_UPI0000D8E0D3 Cluster: UPI0000D8E0D3 related cluster; n...    54   2e-05
UniRef50_Q237L2 Cluster: Kinesin motor domain containing protein...    54   2e-05
UniRef50_A2G9D2 Cluster: Putative uncharacterized protein; n=1; ...    54   2e-05
UniRef50_A2EZ87 Cluster: Viral A-type inclusion protein, putativ...    54   2e-05
UniRef50_A2EXF7 Cluster: Putative uncharacterized protein; n=2; ...    54   2e-05
UniRef50_A2EJ44 Cluster: Viral A-type inclusion protein, putativ...    54   2e-05
UniRef50_A0DPB8 Cluster: Chromosome undetermined scaffold_59, wh...    54   2e-05
UniRef50_Q0UIV9 Cluster: Putative uncharacterized protein; n=1; ...    54   2e-05
UniRef50_A7F074 Cluster: Putative uncharacterized protein; n=2; ...    54   2e-05
UniRef50_UPI0000F1EC3A Cluster: PREDICTED: hypothetical protein;...    53   3e-05
UniRef50_UPI0000E48F58 Cluster: PREDICTED: similar to coiled-coi...    53   3e-05
UniRef50_UPI0000E48EEB Cluster: PREDICTED: similar to Viral A-ty...    53   3e-05
UniRef50_UPI0000DB6E33 Cluster: PREDICTED: similar to CG10542-PA...    53   3e-05
UniRef50_UPI00006CF26E Cluster: Viral A-type inclusion protein r...    53   3e-05
UniRef50_UPI00006CD8FF Cluster: EF hand family protein; n=1; Tet...    53   3e-05
UniRef50_UPI000065CFB6 Cluster: Golgin subfamily A member 3 (Gol...    53   3e-05
UniRef50_UPI0000ECA778 Cluster: UPI0000ECA778 related cluster; n...    53   3e-05
UniRef50_Q4SDN8 Cluster: Chromosome 10 SCAF14634, whole genome s...    53   3e-05
UniRef50_Q23DL9 Cluster: TBC domain containing protein; n=1; Tet...    53   3e-05
UniRef50_Q23081 Cluster: Lin-5 (Five) interacting protein protei...    53   3e-05
UniRef50_Q22WE9 Cluster: TBC domain containing protein; n=1; Tet...    53   3e-05
UniRef50_Q7RYS2 Cluster: Putative uncharacterized protein NCU003...    53   3e-05
UniRef50_Q0UQS6 Cluster: Putative uncharacterized protein; n=1; ...    53   3e-05
UniRef50_A1CKZ1 Cluster: TBC domain protein, putative; n=7; Tric...    53   3e-05
UniRef50_P54697 Cluster: Myosin IJ heavy chain; n=3; Dictyosteli...    53   3e-05
UniRef50_UPI0000D56FEC Cluster: PREDICTED: similar to 150 kDa dy...    53   4e-05
UniRef50_A0YYF5 Cluster: Methyltransferase FkbM; n=1; Lyngbya sp...    53   4e-05
UniRef50_Q7R4B6 Cluster: GLP_480_39976_39086; n=1; Giardia lambl...    53   4e-05
UniRef50_Q7PUP2 Cluster: ENSANGP00000012828; n=1; Anopheles gamb...    53   4e-05
UniRef50_Q23D13 Cluster: Viral A-type inclusion protein repeat c...    53   4e-05
UniRef50_A2FVB6 Cluster: Putative uncharacterized protein; n=2; ...    53   4e-05
UniRef50_A2F6M0 Cluster: Putative uncharacterized protein; n=1; ...    53   4e-05
UniRef50_A0BJN6 Cluster: Chromosome undetermined scaffold_110, w...    53   4e-05
UniRef50_Q2GM58 Cluster: Putative uncharacterized protein; n=5; ...    53   4e-05
UniRef50_A6R705 Cluster: Predicted protein; n=1; Ajellomyces cap...    53   4e-05
UniRef50_Q5QTY8 Cluster: Translation initiation factor IF-2; n=1...    53   4e-05
UniRef50_Q7SXE4 Cluster: Golgin subfamily A member 5; n=9; Eutel...    53   4e-05
UniRef50_Q9BV73 Cluster: Centrosome-associated protein CEP250; n...    53   4e-05
UniRef50_UPI0000E4794A Cluster: PREDICTED: similar to Ornithine ...    52   5e-05
UniRef50_UPI0000DB6B83 Cluster: PREDICTED: similar to lava lamp ...    52   5e-05
UniRef50_UPI00006CBB68 Cluster: Kinesin motor domain containing ...    52   5e-05
UniRef50_UPI00006CB352 Cluster: Viral A-type inclusion protein r...    52   5e-05
UniRef50_Q5SP91 Cluster: Novel protein similar to rho-associated...    52   5e-05
UniRef50_Q4SSB8 Cluster: Chromosome undetermined SCAF14473, whol...    52   5e-05
UniRef50_Q0MYX4 Cluster: Putative rabgap/tbc domain-containing p...    52   5e-05
UniRef50_Q4CVE1 Cluster: Putative uncharacterized protein; n=1; ...    52   5e-05
UniRef50_Q23DA0 Cluster: Putative uncharacterized protein; n=1; ...    52   5e-05
UniRef50_A2FN34 Cluster: Putative uncharacterized protein; n=1; ...    52   5e-05
UniRef50_A2EUZ9 Cluster: Kelch motif family protein; n=1; Tricho...    52   5e-05
UniRef50_A2E8H6 Cluster: Viral A-type inclusion protein, putativ...    52   5e-05
UniRef50_A2D7K4 Cluster: Putative uncharacterized protein; n=1; ...    52   5e-05
UniRef50_A0CYE5 Cluster: Chromosome undetermined scaffold_31, wh...    52   5e-05
UniRef50_Q6C1U3 Cluster: Similar to wi|NCU00551.1 Neurospora cra...    52   5e-05
UniRef50_A6R8N2 Cluster: Putative uncharacterized protein; n=1; ...    52   5e-05
UniRef50_A4RG96 Cluster: Putative uncharacterized protein; n=1; ...    52   5e-05
UniRef50_UPI00015B58DF Cluster: PREDICTED: similar to mitotic ch...    52   7e-05
UniRef50_UPI00015B53AD Cluster: PREDICTED: similar to RHO kinase...    52   7e-05
UniRef50_UPI0000F21489 Cluster: PREDICTED: similar to LOC494846 ...    52   7e-05
UniRef50_UPI00005A0FA9 Cluster: PREDICTED: similar to USP6 N-ter...    52   7e-05
UniRef50_Q1FIV0 Cluster: Putative uncharacterized protein; n=1; ...    52   7e-05
UniRef50_Q5CHP8 Cluster: T10G3.5; n=2; Cryptosporidium|Rep: T10G...    52   7e-05
UniRef50_Q585H6 Cluster: Putative uncharacterized protein; n=2; ...    52   7e-05
UniRef50_Q388X1 Cluster: Putative uncharacterized protein; n=1; ...    52   7e-05
UniRef50_A3H5S7 Cluster: SMC protein-like; n=1; Caldivirga maqui...    52   7e-05
UniRef50_P22793 Cluster: Trichohyalin; n=10; cellular organisms|...    52   7e-05
UniRef50_Q4V328 Cluster: GRIP1-associated protein 1; n=65; Eumet...    52   7e-05
UniRef50_UPI00015B5D72 Cluster: PREDICTED: similar to viral A-ty...    52   9e-05
UniRef50_UPI0000E4997E Cluster: PREDICTED: similar to KIAA1590 p...    52   9e-05
UniRef50_UPI0000E468ED Cluster: PREDICTED: similar to Restin (Re...    52   9e-05
UniRef50_UPI00006CE95F Cluster: Viral A-type inclusion protein r...    52   9e-05
UniRef50_A4RVV7 Cluster: Predicted protein; n=1; Ostreococcus lu...    52   9e-05
UniRef50_Q4QFM2 Cluster: Kinesin K39, putative; n=14; root|Rep: ...    52   9e-05
UniRef50_Q23DU6 Cluster: Putative uncharacterized protein; n=1; ...    52   9e-05
UniRef50_A3FQM5 Cluster: Putative uncharacterized protein; n=2; ...    52   9e-05
UniRef50_A2E0A7 Cluster: Putative uncharacterized protein; n=1; ...    52   9e-05
UniRef50_A0CX58 Cluster: Chromosome undetermined scaffold_3, who...    52   9e-05
UniRef50_A0BZV3 Cluster: Chromosome undetermined scaffold_14, wh...    52   9e-05

>UniRef50_Q9VYY9 Cluster: CG11727-PA, isoform A; n=8;
           Endopterygota|Rep: CG11727-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 807

 Score =  773 bits (1912), Expect = 0.0
 Identities = 406/763 (53%), Positives = 523/763 (68%), Gaps = 32/763 (4%)

Query: 96  IPTSETIPTPDRALLAKLEEENRRIEADAKNA-SLTTVHSRKXXXXXXXXXXXXXXXXHE 154
           +P  E +PT +  LLAKLE  N+ IE+DAK+  SL + HSRK                 +
Sbjct: 25  LPGEENLPTSEMDLLAKLEAANKLIESDAKSLNSLHSTHSRKNSDTS------------Q 72

Query: 155 VETRPTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV 214
           +    +  +  EED+W+ W  ++++WE   KR+N  V +LVR+G+PHHFR IVWQ L+G 
Sbjct: 73  ISLTSSGNSVAEEDIWTTWATILNDWEGALKRKNPCVSELVRRGIPHHFRAIVWQQLSGA 132

Query: 215 DTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDR 274
               +KK YA YIKA SACEKVIRRDIARTYPE +FFKEKDG GQE+LFNV+KAYSLHDR
Sbjct: 133 SDG-DKKQYAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEALFNVIKAYSLHDR 191

Query: 275 EVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQ 334
           EVGYCQGSGFIVGLLLMQMPEEEAFAVLV+IMQQHRMR MFKPSM+ELGLCM+QLENLVQ
Sbjct: 192 EVGYCQGSGFIVGLLLMQMPEEEAFAVLVQIMQQHRMRHMFKPSMSELGLCMYQLENLVQ 251

Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
           E +PD+H+HFQ Q F T++YA               L+CRIMDVFLSEG+E +FKVALAL
Sbjct: 252 EQIPDMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALAL 311

Query: 395 LTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK 454
           L  GK+ LL LDME++LK+ QKELP + EAD   F NLAYS+K+N K+MKK+EKEY  +K
Sbjct: 312 LLTGKDTLLCLDMEAMLKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLK 371

Query: 455 TKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQ 514
            KEQ ++A LR LR+EN LLKQR               VRGQV RAE EE ++A+  E+ 
Sbjct: 372 KKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELM 431

Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAE-------NNSRQSSLEG--TESASGQKHEEL 565
            LRR+ +++  +L  A +E+R L + + E       NNSRQSS++    +  + ++ +E+
Sbjct: 432 QLRRSYLEVSHQLENANEEVRGLSLRLQENNVSIDSNNSRQSSIDELCMKEEALKQRDEM 491

Query: 566 ARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKL 625
             CL                        ++ELE + K+LR    DN+VAHLQDELIA KL
Sbjct: 492 VSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQDELIASKL 551

Query: 626 REAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW-- 683
           REAEA+LSLKDL+QRV ELS  WQR L E+++            + + +TPKKLL  +  
Sbjct: 552 REAEASLSLKDLKQRVQELSSQWQRQLAENQRSE-----SERTTNAVDSTPKKLLTNFFD 606

Query: 684 EGRSAD-MLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLL 742
             +S++   KL+EELMTTRIRE+E LTELKELRLKVMELETQVQVSTNQLRRQDEE + L
Sbjct: 607 SSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKL 666

Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY 802
           +E L+ A+ RE+ +  + RE QH+Y+DLES+ K E M   I+  E +Q +AEL+ E+S  
Sbjct: 667 KEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRL 726

Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
           + KN  M  EGELR  N+DDSD+VR+LQ+++A++KAE+  L++
Sbjct: 727 ETKNSEMLAEGELR-ANLDDSDKVRDLQDRLADMKAELTALKS 768



 Score = 60.5 bits (140), Expect = 2e-07
 Identities = 67/273 (24%), Positives = 123/273 (45%), Gaps = 18/273 (6%)

Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
           IDEL  + ++L+++  D  V+ L +EL+ V+   AE+   +++L+ +V EL E  ++ L+
Sbjct: 475 IDELCMKEEALKQR--DEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEED-KKTLR 531

Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE 713
           E   +   A +Q  +++  +   +  L        D+ +  +EL +   R++      + 
Sbjct: 532 ETTPDNSVAHLQDELIASKLREAEASLSL-----KDLKQRVQELSSQWQRQLAENQRSES 586

Query: 714 LRLKVMELETQVQVSTN--QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
            R       T  ++ TN     +  E  + L E L     RE    T  +E + K  +LE
Sbjct: 587 ERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELE 646

Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEYK-LKNEVMAT-------EGELRNNNMDDS 823
           ++ +  + Q   ++ E  +   ELE  V+  K + N+           E  +++  M+  
Sbjct: 647 TQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVK 706

Query: 824 DRVRELQEQVAELKAEIMRLEAWKSRALGHTEL 856
            +  E  + VAELK EI RLE   S  L   EL
Sbjct: 707 IKFTEQSQTVAELKQEISRLETKNSEMLAEGEL 739


>UniRef50_Q96CN4 Cluster: EVI5-like protein; n=21; Eumetazoa|Rep:
           EVI5-like protein - Homo sapiens (Human)
          Length = 794

 Score =  530 bits (1309), Expect = e-149
 Identities = 301/747 (40%), Positives = 433/747 (57%), Gaps = 67/747 (8%)

Query: 99  SETIPTPDRALLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETR 158
           SE +   +  LLAKLEE+NR +EAD+K+        R                 H     
Sbjct: 27  SENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHL---- 82

Query: 159 PTPGTNGEEDLWSLWGRLVSNWESEWKRRNQ-WVRDLVRQGVPHHFRGIVWQLLAGVDTS 217
                  EED W LWGR+ + WE EW+RR +  +++L+R+G+PHHFR IVWQLL      
Sbjct: 83  -------EEDTWILWGRIANEWE-EWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDM 134

Query: 218 PEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVG 277
           P K  Y+  +K  S CEK+IRRDIARTYPEH+FFK +D LGQE LFNVMKAYSL DREVG
Sbjct: 135 PVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVG 194

Query: 278 YCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELL 337
           YCQGS FIVGLLLMQMPEEEAF V V++MQ++R+R++FKPSMAELGLC++Q E ++QE L
Sbjct: 195 YCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQL 254

Query: 338 PDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTL 397
           PDL+ HF+SQSF TS+YA              P+A R+ D+F+ EG+EIVF+V LALL +
Sbjct: 255 PDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQV 314

Query: 398 GKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
            + +L+ LDME + +Y Q+ +P + ++     +  AY VK NPKKMK+LEKEY  +K+KE
Sbjct: 315 NQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKE 374

Query: 458 QGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALR 517
             +   ++ LR ENRLLKQR+               +GQV RA+  EE + + RE+  +R
Sbjct: 375 MEEQIEIKRLRTENRLLKQRIETLE-----------KGQVTRAQEAEENYVIKRELAVVR 423

Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
                  Q+ + A ++++  + TI +   +Q +   TE        EL +          
Sbjct: 424 -------QQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQ--------SR 468

Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
                           + ++E  N SL     +NNVA LQ+EL A+K+RE +A  S ++L
Sbjct: 469 LRETETLGALREMQDKVLDMEKRNSSLPD---ENNVAQLQEELKALKVREGQAVASTREL 525

Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
           + ++ ELS++WQ HL    +                 +P+KL+         + +L +EL
Sbjct: 526 KLQLQELSDTWQAHLARGGR--------------WKESPRKLV---------VGELQDEL 562

Query: 698 MTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQ 757
           M+ R+RE +AL E +ELR +V+ELETQ  +  N L R + E   L+E L     + + LQ
Sbjct: 563 MSVRLREAQALAEGRELRQRVVELETQDHIHRNLLNRVEAERAALQEKLQYLAAQNKGLQ 622

Query: 758 TRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRN 817
           T+  E + K A+ E K+K E M   +R  +    +AE+   ++E +++ E    +G+L  
Sbjct: 623 TQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQL-- 680

Query: 818 NNMDDSDRVRELQEQVAELKAEIMRLE 844
           N+ D S  +REL++Q+ ELKAE+  L+
Sbjct: 681 NHSDSSQYIRELKDQIEELKAEVRLLK 707



 Score = 41.1 bits (92), Expect = 0.13
 Identities = 67/273 (24%), Positives = 116/273 (42%), Gaps = 36/273 (13%)

Query: 616 LQDELIAVKLREAEANLSLKDLR-------QRVSELSESWQRHLQEH------KQEAPAA 662
           L+ E  A+K +E E  + +K LR       QR+  L +      QE       K+E    
Sbjct: 363 LEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKGQVTRAQEAEENYVIKRELAVV 422

Query: 663 PVQ-SNVVSDIMATPKKLLRAWEGRSADMLK------LDEELMTTRIREVEALTELKELR 715
             Q S+   D+      + +  E +    L       L+ EL  +R+RE E L  L+E++
Sbjct: 423 RQQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQ 482

Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
            KV+++E +     N     +     L+E L A   RE       RE + +  +L     
Sbjct: 483 DKVLDMEKR-----NSSLPDENNVAQLQEELKALKVREGQAVASTRELKLQLQELSD--T 535

Query: 776 YESMQANIRNMEDAQR---IAELETEVSEYKLKNEVMATEG-ELRNN--NMDDSDRV-RE 828
           +++  A     +++ R   + EL+ E+   +L+      EG ELR     ++  D + R 
Sbjct: 536 WQAHLARGGRWKESPRKLVVGELQDELMSVRLREAQALAEGRELRQRVVELETQDHIHRN 595

Query: 829 LQEQV-AELKAEIMRLEAWKSRALG-HTELSRA 859
           L  +V AE  A   +L+   ++  G  T+LS +
Sbjct: 596 LLNRVEAERAALQEKLQYLAAQNKGLQTQLSES 628


>UniRef50_Q4RZR5 Cluster: Chromosome 18 SCAF14786, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 18
           SCAF14786, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 885

 Score =  492 bits (1214), Expect = e-137
 Identities = 297/784 (37%), Positives = 428/784 (54%), Gaps = 90/784 (11%)

Query: 99  SETIPTPDRALLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETR 158
           SE +   +  LLAKLEE+NR +EAD+K+    +   R                 H     
Sbjct: 60  SENLSPDELELLAKLEEQNRLLEADSKSMRSMSGSRRNSGSSLVSSSSASSNLSHL---- 115

Query: 159 PTPGTNGEEDLWSLWGRLVSNWESEWKRR-NQWVRDLVRQGVPHHFRGIVWQLLAGVDTS 217
                  EED W LWGR+V+ WE EW+R+ ++ +++L+R+G+PHHFR IVWQLL      
Sbjct: 116 -------EEDTWILWGRIVNEWE-EWRRKKDKLLKELIRKGIPHHFRAIVWQLLGNATDM 167

Query: 218 PEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKA--------- 268
           P K  Y+  +K  S CEK+IRRDIARTYPEH+FFK +D LGQE LFNVMKA         
Sbjct: 168 PVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKARPVYTPSGL 227

Query: 269 -------------YSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMF 315
                        YSL DREVGYCQGS FIVGLLLMQMPEEEAF V V++MQ++R+R++F
Sbjct: 228 KASSPLQLFGVYAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELF 287

Query: 316 KPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRI 375
           KPSMAELGLC++Q E L+QE LP+L+VHF+SQSF TS+YA              P+A RI
Sbjct: 288 KPSMAELGLCIYQFEYLLQEQLPELNVHFRSQSFHTSMYASSWFLTLFLTFLPLPVATRI 347

Query: 376 MDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYS 435
            D+F+ EG+EI+F+V LA+L   + DL+ LDME + ++ QK +P + ++     +  AY 
Sbjct: 348 FDIFMYEGLEIIFRVGLAILQYNQTDLVQLDMEGMSQHFQKVIPHQFDSCPDKLILRAYQ 407

Query: 436 VKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRG 495
           +K NPK+MKKLEKEYT IK KE  +   ++ LR ENRLLKQR+              ++G
Sbjct: 408 IKYNPKRMKKLEKEYTTIKNKEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQG 467

Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
           QV RA+  EE + + RE+  +R+      + L  A D IR L+                 
Sbjct: 468 QVTRAQEAEENYVIKRELAVVRQQCTAASESLEKAQDTIRELQQ---------------- 511

Query: 556 SASGQKH-EELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA 614
               QK+ E L   LQ                       + +LE  +  L     +NN+A
Sbjct: 512 ----QKYTEPLVTSLQTQLEQSRLREAELLGALKEMQDKVLDLEKRSSCLPD---ENNIA 564

Query: 615 HLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
            LQ+E+  +KLRE E   S +++++ VSEL++ WQ H+            +S        
Sbjct: 565 ALQEEVKQMKLRELEMLRSFREMQETVSELNQRWQLHMSRSGGGGGGHWKES-------- 616

Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQV--------- 725
            PKK           M +L ++LMT R+RE EA  EL+E++LK ++LE+Q          
Sbjct: 617 -PKK---------NAMNELQDKLMTVRLREAEAQAELREVKLKALQLESQPGETLTAALL 666

Query: 726 --QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANI 783
             Q+ +  + R ++E   L++ L A   + +ALQ +  E + K A+ + K+K E M   +
Sbjct: 667 QNQIHSKLIGRNEQERSSLQDRLQALTNQNKALQAQLGEMKRKQAESDCKSKEEVMAVRL 726

Query: 784 RNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
           R  +    +AEL  +++E +++ E    +G+L  N+ D    + +++ Q+ ELK E  +L
Sbjct: 727 READSMAAMAELRQKIAELEIQKEEGLVKGQL--NHSDLRQYINQMKNQITELKNENRQL 784

Query: 844 EAWK 847
              K
Sbjct: 785 RGQK 788



 Score = 40.7 bits (91), Expect = 0.17
 Identities = 50/228 (21%), Positives = 106/228 (46%), Gaps = 20/228 (8%)

Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKL-LRAWEGR--SADMLKLDEELMTTRIREV 705
           Q  L +   E  +   Q  +     + P KL LRA++ +     M KL++E  T + +E+
Sbjct: 371 QTDLVQLDMEGMSQHFQKVIPHQFDSCPDKLILRAYQIKYNPKRMKKLEKEYTTIKNKEM 430

Query: 706 EALTELKELRL-------KVMELETQVQVSTNQL------RRQD-EEARLLRENLDAALQ 751
           E   E+K LR        ++  LE +     ++L      R Q+ EE  +++  L    Q
Sbjct: 431 EEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQ 490

Query: 752 RERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMAT 811
           +  A      + Q    +L+ +   E +  +++   +  R+ E E   +  +++++V+  
Sbjct: 491 QCTAASESLEKAQDTIRELQQQKYTEPLVTSLQTQLEQSRLREAELLGALKEMQDKVL-- 548

Query: 812 EGELRNNNMDDSDRVRELQEQVAELK-AEIMRLEAWKSRALGHTELSR 858
           + E R++ + D + +  LQE+V ++K  E+  L +++      +EL++
Sbjct: 549 DLEKRSSCLPDENNIAALQEEVKQMKLRELEMLRSFREMQETVSELNQ 596


>UniRef50_O60447 Cluster: Ecotropic viral integration site 5 protein
           homolog; n=32; Euteleostomi|Rep: Ecotropic viral
           integration site 5 protein homolog - Homo sapiens
           (Human)
          Length = 810

 Score =  448 bits (1104), Expect = e-124
 Identities = 269/676 (39%), Positives = 367/676 (54%), Gaps = 40/676 (5%)

Query: 97  PTSETIPTPDRA-LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEV 155
           P+S +  +PD   LLAKLEE+NR +E D+K+        R                 H  
Sbjct: 72  PSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHL- 130

Query: 156 ETRPTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD 215
                     EED W LWGR+V+ WE   K++ + V++LV +G+PHHFR IVWQLL    
Sbjct: 131 ----------EEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQ 180

Query: 216 TSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
           + P K  Y+  +K  S CEK+IRRDIARTYPEH+FFKEKD LGQE LFNVMKAYSL DRE
Sbjct: 181 SMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRE 240

Query: 276 VGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQE 335
           VGYCQGS FIVGLLLMQMPEEEAF V VK+MQ +R+R++FKPSMAELGLCM+Q E ++QE
Sbjct: 241 VGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQE 300

Query: 336 LLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
            LP+L VHFQSQSF TS+YA              P+A RI D+F+SEG+EIVF+V LALL
Sbjct: 301 HLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPVATRIFDIFMSEGLEIVFRVGLALL 360

Query: 396 TLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
            + + +L+ LDME +L++ QK +P + +      +  AY VK N KKMKKLEKEYT IKT
Sbjct: 361 QMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKT 420

Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
           KE  +   ++ LR ENRLLKQR+               + +      E+    L++E+  
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLE-----------KHKCSSNYNEDFVLQLEKELVQ 469

Query: 516 LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXX 575
            R +  + Q  L    D++  +E        R +SL   E+   +  EEL          
Sbjct: 470 ARLSEAESQCALKEMQDKVLDIE-------KRNNSLP-DENNIARLQEELIAVKLREAEA 521

Query: 576 XXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLK 635
                                L       +     N +  LQDEL+ ++LREAE    ++
Sbjct: 522 IMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIR 581

Query: 636 DLRQRVSELSESWQ---RHLQEHKQEAPAAPVQSNVVS-DIMATPKKLLRAWEGRSADML 691
           +++QR+ E+    Q    HL+  +QE  +   +   +S        +L  A   ++    
Sbjct: 582 EIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIEC 641

Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVS--TNQLRRQDEEARL--LRENLD 747
           K  EE+M  R+RE +++  + ELR  + ELE Q +      QL + D    +  L++ + 
Sbjct: 642 KNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQI- 700

Query: 748 AALQRERALQTRQREF 763
           A L  E      QR F
Sbjct: 701 AELNHELRCLKGQRGF 716



 Score =  146 bits (354), Expect = 2e-33
 Identities = 90/249 (36%), Positives = 140/249 (56%), Gaps = 27/249 (10%)

Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
           ++E  N SL  +   NN+A LQ+ELIAVKLREAEA + LK+LRQ+V +L E WQRHL   
Sbjct: 490 DIEKRNNSLPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHL--- 543

Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
                     +         PKK           M +L +ELMT R+RE E   E++E++
Sbjct: 544 ----------ARTTGRWKDPPKK---------NAMNELQDELMTIRLREAETQAEIREIK 584

Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
            ++ME+ETQ Q+++N LRR ++E   L+E +     + + L T+  E + K A++E K K
Sbjct: 585 QRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNK 644

Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
            E M   +R  +    +AEL   ++E +++ E    +G+L  N  D +  + EL++Q+AE
Sbjct: 645 EEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQL--NKSDSNQYIGELKDQIAE 702

Query: 836 LKAEIMRLE 844
           L  E+  L+
Sbjct: 703 LNHELRCLK 711



 Score = 49.2 bits (112), Expect = 5e-04
 Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 17/180 (9%)

Query: 690 MLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAA 749
           +L+L++EL+  R+ E E+   LKE++ KV+++E +     N L  ++  AR L+E L A 
Sbjct: 460 VLQLEKELVQARLSEAESQCALKEMQDKVLDIEKR----NNSLPDENNIAR-LQEELIAV 514

Query: 750 LQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA--ELETEVSEYKLK-- 805
             RE       +E + +  DLE   +    +   R  +  ++ A  EL+ E+   +L+  
Sbjct: 515 KLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREA 574

Query: 806 ------NEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSRA 859
                  E+     E+   N  +S+ +R  +++V  L+ ++  L A     L  T+LS A
Sbjct: 575 ETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLL--TQLSEA 632



 Score = 42.3 bits (95), Expect = 0.056
 Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 13/207 (6%)

Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW---EGRSADMLKLDEELMTTRIREV 705
           Q  L +   E      Q  +       P KL++A    +  S  M KL++E  T + +E+
Sbjct: 364 QAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEM 423

Query: 706 EALTELKEL----RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
           E   E+K L    RL    +ET  +   +    +D   +L +E + A L  E   Q   +
Sbjct: 424 EEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLS-EAESQCALK 482

Query: 762 EFQHKYADLESKAKYESMQANIRNMED---AQRIAELETEVSEYKLKNEVMATEGELRNN 818
           E Q K  D+E +      + NI  +++   A ++ E E  +   +L+ +V   E   + +
Sbjct: 483 EMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRH 542

Query: 819 NMDDSDRVRELQEQVA--ELKAEIMRL 843
               + R ++  ++ A  EL+ E+M +
Sbjct: 543 LARTTGRWKDPPKKNAMNELQDELMTI 569


>UniRef50_UPI0000E4947B Cluster: PREDICTED: similar to ecotropic
           viral integration site 5; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ecotropic viral
           integration site 5 - Strongylocentrotus purpuratus
          Length = 880

 Score =  429 bits (1056), Expect = e-118
 Identities = 279/749 (37%), Positives = 416/749 (55%), Gaps = 65/749 (8%)

Query: 106 DRALLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETRPTPGTNG 165
           +  L+AK+EE+NRR+EAD+K  SL +V S +                   E      +  
Sbjct: 154 EEELVAKMEEQNRRLEADSK--SLKSVRSSRRGSNASQQSTSSSTSNLSNEE-----SIS 206

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYAS 225
            +D W +WG++V++W+   K++++ +++LVR G+P HFRGIVWQLL G   SP K+ YA 
Sbjct: 207 MQDQWLVWGKIVNDWDEYTKKKSKQIKELVRLGIPRHFRGIVWQLLCGAYNSPLKEQYAL 266

Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
           Y+K +S+ E+VIRRDIARTYPEH+FFKEKDGLGQE+LFNVMKAYSLHDREVGYCQGS FI
Sbjct: 267 YLKMQSSYERVIRRDIARTYPEHEFFKEKDGLGQETLFNVMKAYSLHDREVGYCQGSAFI 326

Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           VGLLLMQMPEEEAF VLVKIMQ++ MR++FKP+MA LGLCMFQ E ++Q+LLPDL  HF 
Sbjct: 327 VGLLLMQMPEEEAFCVLVKIMQEYGMRELFKPNMAHLGLCMFQFECMIQDLLPDLFKHFT 386

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
           +Q F TS+YA               L+ RIMD+F+SEG+E +FK+  A+L L   DLL L
Sbjct: 387 AQGFHTSMYASSWFLTLFAVCLPISLSMRIMDLFISEGMEAIFKIGAAMLQLNCEDLLRL 446

Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLR 465
           DME +L++IQK  P   E +    +  +Y +K N KKMK+LEK+Y   K KE  +   +R
Sbjct: 447 DMEEMLRFIQKLAPKIHEDEPEHLLQSSYLIKYNAKKMKRLEKDYFAFKEKETEEQIEMR 506

Query: 466 CLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRRANVDMQQ 525
            LR ENRLL QR+                  +++    + ++AL   V       +++Q+
Sbjct: 507 RLRTENRLLHQRIQ----------------NLEKENEHKCSYALVESVV------MELQE 544

Query: 526 RL-AVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXX 584
            L +V L E  S E ++   +++  SLE       ++       LQ              
Sbjct: 545 ELISVRLKEAESAE-SLKTFSTKIESLEKINQKLRKEPGHSIAALQDELIAVKLREAEAN 603

Query: 585 XXXXXXXXXIDELENE-----NKSLRRQRVDNNVAHLQ---DELIAVKLREAEANLSLKD 636
                    +++LE+       K   +Q+  N+   LQ   +EL++V+LREA+    LK+
Sbjct: 604 LALRELREKVNDLESHWQKHLEKLTGKQKGSNSRPTLQQVTEELMSVRLREADTAADLKE 663

Query: 637 LRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK---LLRAWEGRSADMLKL 693
            +QRV EL    Q       Q       +  V  D+    KK   L R +     ++ KL
Sbjct: 664 TQQRVMELQTQNQ---MTSNQMRRIEEERIEVKQDLEVCEKKEQELQRQFYEAQKELCKL 720

Query: 694 D----EELMTTRIREVEALTELKELRLKV--MELETQVQVSTNQLRRQDEEARL--LREN 745
           +    EE++  R+RE E+  EL ELR +V  ++++    ++ N L + +   R+  L++ 
Sbjct: 721 EARSKEEMINMRLREAESNAELIELRQRVSGLDIQNSELITKNSLIQAESYHRVEELKDR 780

Query: 746 LDAALQRERALQTRQREFQ--HKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYK 803
           +   L+RE A+  ++   +   K  D+E      + + +   ++  QR+  LE E +E  
Sbjct: 781 I-MELKREVAVFKKRERLRSGEKAIDIE-----RTTEDDPELIQREQRV--LEDEANEAN 832

Query: 804 LKNEVMATEGELRNNNMDDSDRVRELQEQ 832
              EVM  +  +  ++ +D D + E+ ++
Sbjct: 833 -HEEVMGIDISIIESD-NDEDIIAEISDE 859



 Score =  139 bits (336), Expect = 4e-31
 Identities = 86/247 (34%), Positives = 146/247 (59%), Gaps = 25/247 (10%)

Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
           I+ LE  N+ LR++   +++A LQDELIAVKLREAEANL+L++LR++V++L   WQ+HL+
Sbjct: 567 IESLEKINQKLRKEP-GHSIAALQDELIAVKLREAEANLALRELREKVNDLESHWQKHLE 625

Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE 713
           +                    T K+  +    R   + ++ EELM+ R+RE +   +LKE
Sbjct: 626 K-------------------LTGKQ--KGSNSRPT-LQQVTEELMSVRLREADTAADLKE 663

Query: 714 LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESK 773
            + +VMEL+TQ Q+++NQ+RR +EE   ++++L+   ++E+ LQ +  E Q +   LE++
Sbjct: 664 TQQRVMELQTQNQMTSNQMRRIEEERIEVKQDLEVCEKKEQELQRQFYEAQKELCKLEAR 723

Query: 774 AKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQV 833
           +K E +   +R  E    + EL   VS   ++N  + T+  L     +   RV EL++++
Sbjct: 724 SKEEMINMRLREAESNAELIELRQRVSGLDIQNSELITKNSL--IQAESYHRVEELKDRI 781

Query: 834 AELKAEI 840
            ELK E+
Sbjct: 782 MELKREV 788



 Score = 49.2 bits (112), Expect = 5e-04
 Identities = 65/267 (24%), Positives = 114/267 (42%), Gaps = 25/267 (9%)

Query: 596 ELENENK-SLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
           E E E +  +RR R +N + H + + +    +E E   S   +   V EL E       +
Sbjct: 496 EKETEEQIEMRRLRTENRLLHQRIQNLE---KENEHKCSYALVESVVMELQEELISVRLK 552

Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
             + A +    S  +  +    +KL R   G S  +  L +EL+  ++RE EA   L+EL
Sbjct: 553 EAESAESLKTFSTKIESLEKINQKL-RKEPGHS--IAALQDELIAVKLREAEANLALREL 609

Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
           R KV +LE+  Q    +L  + + +   R  L    +   +++ R+ +     ADL+ + 
Sbjct: 610 REKVNDLESHWQKHLEKLTGKQKGSNS-RPTLQQVTEELMSVRLREADTA---ADLK-ET 664

Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
           +   M+   +N   + ++  +E E  E K   EV                + +ELQ Q  
Sbjct: 665 QQRVMELQTQNQMTSNQMRRIEEERIEVKQDLEVC-------------EKKEQELQRQFY 711

Query: 835 ELKAEIMRLEAWKSRALGHTELSRAIS 861
           E + E+ +LEA     + +  L  A S
Sbjct: 712 EAQKELCKLEARSKEEMINMRLREAES 738


>UniRef50_UPI0000F1D57B Cluster: PREDICTED: similar to ecotropic
           viral integration site 5; n=1; Danio rerio|Rep:
           PREDICTED: similar to ecotropic viral integration site 5
           - Danio rerio
          Length = 575

 Score =  277 bits (678), Expect = 1e-72
 Identities = 165/472 (34%), Positives = 253/472 (53%), Gaps = 33/472 (6%)

Query: 88  VSSLDDCRIPTSETIPTPDRALLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXX 147
           VSSL     P SE + T +  LLAKLEE+NR +E D+K  SL +V+              
Sbjct: 6   VSSLSST--PGSE-LSTDEMKLLAKLEEQNRLLETDSK--SLYSVNG------------- 47

Query: 148 XXXXXHEVETRPT-PGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGI 206
                  V   PT P T   E+  ++W  +++ WE   KR+   ++ L R+GVP H R +
Sbjct: 48  -------VLRNPTSPKTFSLEE--NIWENVINEWEDWSKRKVGQIKVLTRKGVPAHLRAM 98

Query: 207 VWQLLAGVDTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVM 266
           VWQLL        +  Y+  +K+ S  E +I RD+ RT+P H  F     + +E+LFNV+
Sbjct: 99  VWQLLCDSGNVSVRPQYSDLLKSSSPSETLIHRDLTRTFPHHQLFHNHQSISKETLFNVL 158

Query: 267 KAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCM 326
           KAYS+ D+E+GYC+GS FIVGLLL QM EEEAF V V++M+  RMR+++K S  ELG C+
Sbjct: 159 KAYSVLDQEIGYCKGSVFIVGLLLTQMAEEEAFCVFVRLMKDFRMRELYKSSRDELGCCI 218

Query: 327 FQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEI 386
           +Q +++++E LP+LH HFQ+Q F TS+++                A RI D+F+ EG+EI
Sbjct: 219 YQFDSMIKEQLPELHSHFQTQGFQTSVFSSSWFYSIFLSSLPISAAMRIFDIFMCEGLEI 278

Query: 387 VFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
           VF+V LA+L + + +L+ LD E ++K +Q     ++  D    +  AY +K N  +MK+ 
Sbjct: 279 VFRVGLAVLDMKQTELIKLDNEGMMKCLQNLESWESNPD--LMIEAAYQIKYNGSQMKQF 336

Query: 447 EKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEET 506
            K+Y  IK KE  +   L+ L  EN+ LK R+              +R ++++    +  
Sbjct: 337 RKDYEAIKAKELEEQEELKGLCSENKHLKHRLAILERRCSEKLVSQLRKELEKT---QLN 393

Query: 507 FALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
            A  +      +AN    +  A+ + E R   + I         + GT  A+
Sbjct: 394 IASSQNALKEMQANTSQLEEAALVICETRVAALVIRGTREAVLGICGTREAA 445


>UniRef50_Q9Y3P9 Cluster: Rab GTPase-activating protein 1; n=95;
           Euteleostomi|Rep: Rab GTPase-activating protein 1 - Homo
           sapiens (Human)
          Length = 1069

 Score =  251 bits (615), Expect = 6e-65
 Identities = 140/401 (34%), Positives = 215/401 (53%), Gaps = 8/401 (1%)

Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK-KLYAS 225
           E +   WG L+S W      R + +  LVR GVP   RG VWQLLAG   +    + Y  
Sbjct: 535 EKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRI 594

Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
            I  +S  +  I RDI RT+P HD+FK+  G GQ+SL+ + KAYS++D E+GYCQG  F+
Sbjct: 595 LITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFL 654

Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
             +LL+ MPEE+AF+VLVKIM  + +R++FK +  +L    +QLE L+QE +PDL+ HF 
Sbjct: 655 AAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFL 714

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
             S    +YA               +   I+D+ L EGI ++F VAL LL   K+DLL  
Sbjct: 715 DISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLT 774

Query: 406 DMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAV 463
           D E  LK+ + +LP +  +++ A   M LA ++K++ KK+KK EKEY  ++ ++      
Sbjct: 775 DFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDP 834

Query: 464 LRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFALDREVQALRRA 519
           +    +ENR L++                V  ++    D    EE+  AL++E+   ++ 
Sbjct: 835 IERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQK 894

Query: 520 NVDMQQRLAVALDEIRSL-EMTIAENNSRQSSLEGTESASG 559
            +D ++      +E   L EM   E +  +S ++   S  G
Sbjct: 895 LIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIG 935



 Score = 35.1 bits (77), Expect = 8.5
 Identities = 32/135 (23%), Positives = 68/135 (50%), Gaps = 9/135 (6%)

Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH-KYADLESKAK 775
           K+MEL   +++S  +L++ ++E   +RE      Q+E  ++  +RE +  + A++  + +
Sbjct: 799 KLMELACNMKISQKKLKKYEKEYHTMREQ---QAQQEDPIERFERENRRLQEANMRLEQE 855

Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
            + +   +   + A R      E     L  E++ T+ +L    +D  +  R L+E+ A+
Sbjct: 856 NDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKL----IDAEEEKRRLEEESAQ 911

Query: 836 LKAEIMRLEAWKSRA 850
           LK E+ R E  K+ +
Sbjct: 912 LK-EMCRRELDKAES 925


>UniRef50_A7SQA7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 895

 Score =  248 bits (608), Expect = 4e-64
 Identities = 131/314 (41%), Positives = 187/314 (59%), Gaps = 6/314 (1%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK-KLYA 224
           E++L S W  L+S W+    R  Q V+ LVR+G+P   RG VWQ++AG+  + E    Y 
Sbjct: 370 EQELCS-WSELLSKWKDVSTRPRQLVQ-LVRKGIPEPLRGQVWQMMAGLSENDELVDSYK 427

Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
                +S  E+VI  DI RT+P HD+FK+  G GQE+L+ + KAYS++D EVGYCQG  F
Sbjct: 428 HLFTKESPTEQVIVWDIHRTFPAHDYFKDSGGEGQEALYKISKAYSVYDEEVGYCQGLSF 487

Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
            + +LL+ MPEE+AFAVLVKIM  + +R++F+     L L  +QLE ++++ +PDL  HF
Sbjct: 488 FIAVLLLHMPEEQAFAVLVKIMSAYGLREVFRNDFQLLHLKFYQLERMIEDSMPDLFSHF 547

Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
           Q  +    +YA              P+   IMD+ L EG  ++F+VALALL   + DLL 
Sbjct: 548 QHNNVEAHMYASQWFLTMFTARFPLPMVYSIMDLILCEGTHVIFQVALALLKDARKDLLQ 607

Query: 405 LDMESILKYIQKELPLK--AEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKE-QGDI 461
           +D E ILK+ +  +P K   E      +  A  +KV PKK++K EKEY  IK KE Q + 
Sbjct: 608 MDFEGILKFFRVSMPKKYMEEERYKQLLGCAIGIKVTPKKLRKYEKEYEAIKEKEAQLED 667

Query: 462 AVLRCLRQENRLLK 475
            V R  R+  RL++
Sbjct: 668 PVERFKRENKRLVE 681


>UniRef50_A0MJ37 Cluster: P21; n=11; Caenorhabditis|Rep: P21 -
           Caenorhabditis remanei
          Length = 212

 Score =  245 bits (599), Expect = 5e-63
 Identities = 114/213 (53%), Positives = 153/213 (71%), Gaps = 1/213 (0%)

Query: 193 DLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFK 252
           +LV++G+P HFR I WQ L+    S    LY+ Y++  S  EKVI+RDI RTYPE DFFK
Sbjct: 1   ELVKKGIPQHFRMIAWQNLSNASVSSVHDLYSDYMRQTSVYEKVIQRDIPRTYPELDFFK 60

Query: 253 EKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMR 312
           + +  GQ  LFNV+KAYS+HD+EVGYCQGS FIVGLLL+QMPEEEAFAVLV +M+ +R+R
Sbjct: 61  DGER-GQSLLFNVIKAYSVHDKEVGYCQGSAFIVGLLLLQMPEEEAFAVLVSLMENYRLR 119

Query: 313 DMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLA 372
           +++KP+M +LGLCMFQLE LVQ+ +PDL+ HF +  F TS+YA               +A
Sbjct: 120 ELYKPTMTDLGLCMFQLECLVQDQMPDLYTHFNNMGFDTSMYASSWFLTLFTTTMPLDIA 179

Query: 373 CRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            RIMD FL EG++ +F +++A+L   + +LL L
Sbjct: 180 NRIMDCFLVEGMDYIFCISIAILQQARIELLRL 212


>UniRef50_UPI00015B4BF6 Cluster: PREDICTED: similar to rab6 gtpase
           activating protein, gapcena (rabgap1 protein); n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to rab6
           gtpase activating protein, gapcena (rabgap1 protein) -
           Nasonia vitripennis
          Length = 1056

 Score =  239 bits (586), Expect = 2e-61
 Identities = 117/287 (40%), Positives = 174/287 (60%), Gaps = 2/287 (0%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK-LYASYIKAKS 231
           W  ++ +W+   +R    V+ L RQG+P   RG VWQ L+  D S E    Y   I  +S
Sbjct: 547 WAEVLDSWQVNEQRPKLLVK-LARQGIPEALRGEVWQRLSNCDNSQEMMDKYRMLITKES 605

Query: 232 ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM 291
           +CE VI RDI RT+P HDFFKE  GLGQ+SL+ + KAY+++D E+GYCQG  F+V  LL+
Sbjct: 606 SCEGVILRDINRTFPAHDFFKETGGLGQDSLYRISKAYAVYDEEIGYCQGLSFLVASLLL 665

Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFST 351
            MPEE+AF VLVK+M  + +RD++K     L +  +QL  L+++ LP+L+ HF  +   T
Sbjct: 666 HMPEEQAFCVLVKLMYGYGLRDLYKDRFDNLHMRFYQLNRLMEDQLPELYKHFCDRGIET 725

Query: 352 SLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESIL 411
            ++A               L   I+DVFL +G++ +F+VALALLTL K +LL LD ES L
Sbjct: 726 HMFAAQWFLTLFTARFPLYLVFHILDVFLLQGLDTLFQVALALLTLCKKELLQLDFESTL 785

Query: 412 KYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQ 458
           KY +  LP +  +++ +   +  +  +  KK+KK E E+  +K  ++
Sbjct: 786 KYFRVHLPKRCRSEEVSRYVMKLACSITLKKLKKYEAEFMALKEAQE 832


>UniRef50_UPI0000DB6E1D Cluster: PREDICTED: similar to CG7112-PA,
           partial; n=2; Apis mellifera|Rep: PREDICTED: similar to
           CG7112-PA, partial - Apis mellifera
          Length = 825

 Score =  239 bits (585), Expect = 2e-61
 Identities = 117/283 (41%), Positives = 172/283 (60%), Gaps = 2/283 (0%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK-LYASYIKAKS 231
           W  ++ +W+   +R    ++ L +QG+P   RG VWQ L+  D S E    Y + I  +S
Sbjct: 544 WAEVLDSWQVNEQRPKLLIK-LTKQGIPEALRGEVWQRLSNCDNSQEMMDRYRTLITKES 602

Query: 232 ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM 291
           +CE VI RDI RT+P HDFFKE  GLGQ+SL+ + KAY+++D EVGYCQG  F+V  LL+
Sbjct: 603 SCESVILRDINRTFPAHDFFKETGGLGQDSLYRISKAYAVYDEEVGYCQGLSFLVASLLL 662

Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFST 351
            MPEE+AF VLVK+M  + +RD++K     L +  +QL  L+++ LP+L+ HF  +   T
Sbjct: 663 HMPEEQAFCVLVKLMYDYGLRDLYKDRFDNLHMRFYQLNRLIEDQLPELYKHFCDRGVET 722

Query: 352 SLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESIL 411
            ++A               L   I+DVFL +G++ +F+VALALL L K +LL LD ESIL
Sbjct: 723 HMFAAQWFLTLFTARFPLYLVFHILDVFLLQGLDTLFQVALALLMLCKKELLQLDFESIL 782

Query: 412 KYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK 454
           KY +  LP +   ++ +   +  +  V  KK+KK E E+  +K
Sbjct: 783 KYFRVHLPKRCRNEEVSRYVMKLACSVTLKKLKKYEAEFMTLK 825


>UniRef50_Q967F6 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 934

 Score =  230 bits (563), Expect = 1e-58
 Identities = 142/406 (34%), Positives = 209/406 (51%), Gaps = 23/406 (5%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-----DTSPEK 220
           +E+   +W +L+ NW+ +   R Q + +LV  G+P   RG VWQLL+ V     D     
Sbjct: 391 KEEHLEMWDQLIENWDQQ-SDRPQKISELVLDGIPDKLRGRVWQLLSNVRILAIDQPDLV 449

Query: 221 KLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQ 280
           + Y  ++      E+VI RDI RT+P HD+FKE  G GQ+SL+ + K YSL+D EV YCQ
Sbjct: 450 EKYHIFLSQPCPSEQVIMRDIHRTFPAHDYFKESQGKGQQSLYKISKVYSLYDEEVSYCQ 509

Query: 281 GSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDL 340
           G  F+   LL+ MPEE+AF  LVKIM  + +RD+FK     L L  FQL  L+++ +PDL
Sbjct: 510 GLSFLAASLLLHMPEEQAFCTLVKIMFNYGLRDLFKLGFDNLHLRFFQLTALLKDYIPDL 569

Query: 341 HVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKN 400
             H +     T +YA               +   I+D+FLS+G+  +F ++LALL   K 
Sbjct: 570 SHHLEHIGIETHMYASQWFLTLFTAKFPLQMVFFILDLFLSQGMNTIFHISLALLDDAKT 629

Query: 401 DLLSLDMESILKYIQKELPLK--AEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKE- 457
           DLL LD E  LKY +  LP K   EA     ++ A   ++N  K++  E EY  IK  E 
Sbjct: 630 DLLQLDFEGTLKYFRVSLPRKYRTEASTKCLIHKAVKFRLNHSKLEVYENEYKRIKELER 689

Query: 458 QGDIAVLRCLR-----QENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDRE 512
           + +  VLR  +     Q N L  +R               +R ++D AE + ET A    
Sbjct: 690 ENEDPVLRMEKEIGRHQANTLRLERENDDLAHELVTSKIELRRKLDVAEDQIETSA--NA 747

Query: 513 VQALRRANVDM---QQRLAVALDEIRSL----EMTIAENNSRQSSL 551
           ++ L R N+D+    + L    ++I+ +     + + EN SR   L
Sbjct: 748 IERLTRQNMDILEENKNLMREYEQIKEMYRRDVLRLEENGSRAEKL 793


>UniRef50_Q5K9R8 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 644

 Score =  221 bits (539), Expect = 9e-56
 Identities = 121/324 (37%), Positives = 175/324 (54%), Gaps = 5/324 (1%)

Query: 100 ETIPTPDRALLAKLEEENRRIEADAKNAS---LTTVHSRKXXXXXXXXXXXXXXXXHEVE 156
           E+ PT DR L   L    R  E   K  S      +  R+                  + 
Sbjct: 163 ESAPTRDRRLSKDLSVYERGREGFEKVRSEMDSAAMEMRRERQSRRTSTYISSADAPAIR 222

Query: 157 TRPT-PGTNGEEDL-WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV 214
           T  T P T  EE++ W+ WG +V  +E     R + +   ++QGVP   RG VWQL++  
Sbjct: 223 TPDTIPETPEEEEVDWTFWGSVVQGYEQVALARPKDLSKAIQQGVPPVIRGAVWQLMSSS 282

Query: 215 DTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDR 274
            +   ++ Y + +K  S  EK I +D+ RT+P H +FKE  G+GQE LF V+KAYSL+D+
Sbjct: 283 KSLDLEEAYKALLKLSSPHEKAIMKDLNRTFPNHKYFKEGGGVGQEGLFMVVKAYSLYDQ 342

Query: 275 EVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQ 334
           EVGY QG  FIV  LL+ MP+EEAF VLV++M  + +R  +   M  L L +FQ + LV+
Sbjct: 343 EVGYTQGLAFIVAALLLNMPDEEAFCVLVRLMDSYNLRSHYTAEMQGLQLRLFQFDRLVE 402

Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
           E+LP LH HF  +   +S+YA               L  R++D+  +EGIE VF+ +LAL
Sbjct: 403 EILPLLHTHFVRKGVKSSMYASQWFMTLFSYRFPLSLVYRVLDIVFAEGIEAVFRFSLAL 462

Query: 395 LTLGKNDLLSLDMESILKYIQKEL 418
           L   +  L+ LD E IL+++Q +L
Sbjct: 463 LKKSEEKLVQLDFEEILQFLQADL 486


>UniRef50_Q8MT33 Cluster: RE63030p; n=8; Diptera|Rep: RE63030p -
           Drosophila melanogaster (Fruit fly)
          Length = 1005

 Score =  220 bits (538), Expect = 1e-55
 Identities = 114/293 (38%), Positives = 169/293 (57%), Gaps = 3/293 (1%)

Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK-LYAS 225
           +D    W  ++  W+SE + +N  +  LVR GVP   R  +WQ LA V+   E    Y  
Sbjct: 488 QDTLDEWDPILREWDSEKRPKN--LAPLVRLGVPEALREKIWQKLANVEGRMEMNDKYKI 545

Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
            I  ++ CE VI+RDI RT+P H  FKE  G GQ++LF V KAY++HD EVGYCQG  FI
Sbjct: 546 LITKETKCETVIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFI 605

Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
              LL+ MPEE+AF VLV +M  + +RD++K     L L ++QLE L+++ LP LH HF 
Sbjct: 606 AASLLLHMPEEDAFCVLVALMYDYGLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFT 665

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
           +    T +YA                   ++DVFL +G+ ++F+VA+ LL++ ++DL  L
Sbjct: 666 ACGIETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQL 725

Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQ 458
           D E ILKY +  LP K  +   A   +  + +   KK+K+ E+E+ + K  ++
Sbjct: 726 DFEGILKYFRVTLPKKCRSSSQARKVMKQACERKIKKLKQYEEEFLLKKQHKE 778


>UniRef50_Q4P8R3 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 991

 Score =  216 bits (528), Expect = 2e-54
 Identities = 99/260 (38%), Positives = 159/260 (61%)

Query: 159 PTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP 218
           P      ++  W  WG ++SN++S  +   + +   ++ G+P   RG++WQL++      
Sbjct: 552 PADDVTDDQIDWEFWGEVMSNYQSVARNHPRQLSRAIQAGIPPALRGMMWQLMSSSKNEE 611

Query: 219 EKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGY 278
            + +YA Y+K  SA EK IRRD+ RT+PE D+F++  G+GQE+LFNV+KAYSL+D EVGY
Sbjct: 612 MEIIYAYYLKQTSAHEKAIRRDLNRTFPEQDYFQDGKGIGQENLFNVIKAYSLYDPEVGY 671

Query: 279 CQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLP 338
           CQG  F+VG LL+ MP+EEAF+  V++M+ + +R  F P+M  L L +FQ + L+++LLP
Sbjct: 672 CQGMQFVVGPLLLNMPDEEAFSTFVRLMKSYDLRGHFTPNMPALQLRLFQFDRLLEDLLP 731

Query: 339 DLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLG 398
            LH H   Q   +S+YA                  R++D   +EG+E +F+ AL+L+   
Sbjct: 732 LLHRHLVRQGVKSSMYASQWFMTLFSYRFPLDFVYRVLDSVFAEGVEALFRFALSLMKKN 791

Query: 399 KNDLLSLDMESILKYIQKEL 418
           +  LL L  + ++ +++ EL
Sbjct: 792 EEVLLGLGFDGVVAFLKGEL 811


>UniRef50_Q5BW46 Cluster: SJCHGC05536 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC05536 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 540

 Score =  196 bits (479), Expect = 2e-48
 Identities = 127/377 (33%), Positives = 192/377 (50%), Gaps = 21/377 (5%)

Query: 204 RGIVWQLLAGVDTSPEKKLYASYIKAKSAC--EKVIRRDIARTYPEHDFFKEKDGLGQES 261
           R  V QLL+G        + A  I     C  ++VIRRD+ART+P H FF++K  +GQES
Sbjct: 1   RAEVCQLLSGCPIDETGLMDAYRILVTKPCKHDEVIRRDLARTFPAHSFFRDK--IGQES 58

Query: 262 LFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAE 321
           LF V +AY+L+D EVGYCQG  F   +LL+ MP E+AF VLV++   + +R+ F      
Sbjct: 59  LFLVSRAYALYDEEVGYCQGLTFFAAVLLLHMPVEQAFTVLVQVNNNYGVREFFLNDFDG 118

Query: 322 LGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLS 381
           L + +FQL  ++Q+ LPD+  HF      T ++A               +   I+D+FL+
Sbjct: 119 LHMRLFQLGRIIQDQLPDVSKHFTDLGLETHMFASQWFLTLFTAKFPLNVVFHIVDLFLT 178

Query: 382 EGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQA--AFMNLAYSVKVN 439
           EG+  +F+V+LALL L + DLL LD E +LKY++  +P K     A    +++A S KV 
Sbjct: 179 EGLIFIFRVSLALLQLARRDLLGLDFEGVLKYLRVTMPKKYLTQDANEELLSIALSAKVT 238

Query: 440 PKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVX------XXXXXXXXXXXXXV 493
             K++K  KE+   + +E+   + L  +  +  LL++ V                    +
Sbjct: 239 TSKLQKYAKEWIAKRAQEKFTESPLHVMECQLALLRREVARLEHENESLASGLLTSKTSM 298

Query: 494 RGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG 553
             QVDR E + E   L RE+ A R+   D Q     AL+E   LE  + +      S   
Sbjct: 299 HKQVDRLEDKAE--ILTRELFASRQ---DFQN----ALEEKAHLENEVLQVKKMFRSALE 349

Query: 554 TESASGQKHEELARCLQ 570
             SA  ++H  +  C Q
Sbjct: 350 ENSAELERHRHIFTCYQ 366


>UniRef50_O81347 Cluster: Plant adhesion molecule 1; n=11;
           Magnoliophyta|Rep: Plant adhesion molecule 1 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 356

 Score =  188 bits (458), Expect = 6e-46
 Identities = 111/304 (36%), Positives = 176/304 (57%), Gaps = 13/304 (4%)

Query: 156 ETRPTPGTNGEEDLWSLWGRLVSNWESEWK----RRNQWVRDLVRQGVPHHFRGIVWQLL 211
           +T+ +     EE   + W +++    S+WK    R+   V+  +R+G+P   RG+VWQL+
Sbjct: 39  KTKSSINYEKEEKRVTKWRKMIGTGGSDWKHYVRRKPHVVKRRIRKGIPDCLRGLVWQLI 98

Query: 212 AGVDTS--PEKKLYASY-IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKA 268
           +G          +Y    I   SA E  I RDI+RT+P H FF+++ G GQ SL+NV+KA
Sbjct: 99  SGSRDLLLMNPGVYVQLVIYETSASELDIIRDISRTFPSHVFFQKRHGPGQRSLYNVLKA 158

Query: 269 YSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ---QHRMRDMFKPSMAELGLC 325
           YS++DR+VGY QG GFI GLLL+ M EE+AF +LV +++      +  +++  +  +   
Sbjct: 159 YSVYDRDVGYVQGMGFIAGLLLLYMSEEDAFWLLVALLKGAVHSPIEGLYQAGLPLVQQY 218

Query: 326 MFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIE 385
           + Q + LV+EL+P L  HF  +  + S+YA                A RI DVFL+EG++
Sbjct: 219 LLQFDQLVRELMPKLGEHFTQEMINPSMYASQWFITVFSYSLPFHSALRIWDVFLAEGVK 278

Query: 386 IVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKK 445
           IVFKV LALL    +DLL L  E ++ +  +  P  A  D    + LAYS+KV+ K++++
Sbjct: 279 IVFKVGLALLKHCHDDLLKLPFEELM-HALRNFPEDA-MDPDTLLPLAYSIKVS-KRLEE 335

Query: 446 LEKE 449
           ++++
Sbjct: 336 MKQD 339


>UniRef50_Q6C199 Cluster: Similar to tr|Q12344 Saccharomyces
           cerevisiae YPL249c; n=1; Yarrowia lipolytica|Rep:
           Similar to tr|Q12344 Saccharomyces cerevisiae YPL249c -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 696

 Score =  178 bits (433), Expect = 6e-43
 Identities = 107/395 (27%), Positives = 193/395 (48%), Gaps = 22/395 (5%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           W  W R++ ++ +  K   + +++ +  G P   R I+WQ++     +  +  Y   +K 
Sbjct: 270 WDFWSRVIEDYATVAKEHPKQLKEAISAGFPTELRSIIWQIITSSKNAALQDFYTEILKE 329

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
            +  EK IRRD++RT     F  E      +SL+NV+KAYSL D EVGY QG  F+   L
Sbjct: 330 STPHEKAIRRDLSRT----SFVMETS---PDSLYNVIKAYSLFDPEVGYTQGMAFVTTPL 382

Query: 290 LMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSF 349
           L+ + E +AF +LV++++ + +R MF   M  L L ++Q + L+++ +P +H+H   Q  
Sbjct: 383 LLTLNEVDAFCLLVRLLKDYELRTMFLQEMPGLHLKLYQFDRLLEDQVPSVHIHLTRQGV 442

Query: 350 STSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMES 409
            +S+YA               +  RI D+ ++EGIE + K  +AL+    + +L+L  + 
Sbjct: 443 KSSMYASQWFLTLFAYKFPLSMVLRIFDIIMTEGIEAILKFGVALIRKNADTILALKFDH 502

Query: 410 ILKYIQKEL--PLKAEADQA----AFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAV 463
           +L ++++ +    +  A        F+  A  VK++P  + K ++EY  I   E+  +  
Sbjct: 503 LLPFLKESIFDVYREGAGDVFRVNEFVRDAMDVKIHPLLLHKYQEEYLEINRLERERLEE 562

Query: 464 LRCLRQEN-------RLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQAL 516
           +  LR  N       R ++  +              V+G+V  A  ++E   L+ +V  +
Sbjct: 563 VEALRLANGQLTLQVRRIESTLVALEKEHIEVANEMVQGKVKLASLQDENETLNMQVSEM 622

Query: 517 RRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSL 551
           RR   D  + L   +D  +  E  +AEN   QS +
Sbjct: 623 RRITGD--EDLEALMDLRQDNERLVAENEQLQSQM 655


>UniRef50_Q38A97 Cluster: GTPase activating protein, putative; n=1;
           Trypanosoma brucei|Rep: GTPase activating protein,
           putative - Trypanosoma brucei
          Length = 418

 Score =  177 bits (432), Expect = 8e-43
 Identities = 101/295 (34%), Positives = 160/295 (54%), Gaps = 12/295 (4%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDT---SPEKKLYASYIKA 229
           W ++ +NWES  K+R   V+   R+G+P  FRG  WQLL G      +P  +     ++ 
Sbjct: 126 WQKMQANWESMSKKRRSKVKSRCRKGIPSSFRGAAWQLLIGSYLEMLNPGNEGTYDCLRL 185

Query: 230 KSACEK----VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
           K   ++     I RD+ RT+P+H  F+E+ G+GQ  L NV+ AY+  D EVGY QG  F+
Sbjct: 186 KDISDEGLKGTISRDLPRTFPKHVLFREEGGIGQTFLRNVLHAYANIDPEVGYVQGMAFV 245

Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
           VG L  QM EEE F  L  +M  +++R+R+M+KP    L    +QL+ L+ +LLP+L+ H
Sbjct: 246 VGALYTQMTEEETFWALHTLMNGEKYRLREMYKPGFPMLHKLFYQLQRLMAKLLPNLYEH 305

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
           F+      + YA                  RI D+FLSEG +I+F++A+ LL L +  LL
Sbjct: 306 FEELGVHPTYYASRWFMTLFVYDFNFRAVLRIWDIFLSEGWKIIFRIAIVLLKLEERRLL 365

Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQ 458
           ++  E I+ +  K L    + D+   +  A+ V+    +++   +EY + K + Q
Sbjct: 366 AMSFEEII-FATKTLEQGKDPDE--LIRRAHGVRFKTAELEAFAREYELNKREGQ 417


>UniRef50_Q5CR60 Cluster: TBC domain containing protein; n=2;
           Cryptosporidium|Rep: TBC domain containing protein -
           Cryptosporidium parvum Iowa II
          Length = 359

 Score =  171 bits (417), Expect = 5e-41
 Identities = 87/252 (34%), Positives = 150/252 (59%), Gaps = 7/252 (2%)

Query: 195 VRQGVPHHFRGIVWQLLAGVD---TSPEKKLYASYIKAKSA-CEKVIRRDIARTYPEHDF 250
           +R+G+P  FRG +W  LA V+   +   + LY    + K+A C   I RDI+RT+P H  
Sbjct: 111 LRKGIPAQFRGFIWMKLAEVENIKSEHSENLYYQLSEIKNAPCCGDIYRDISRTFPRHSL 170

Query: 251 FKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHR 310
           F++K+  GQ SLF+V++AYSL++ +VGYCQG GFIVG+LLM M EE++F +L+ I+ +++
Sbjct: 171 FRDKNNHGQNSLFSVLRAYSLYNPDVGYCQGMGFIVGVLLMYMSEEDSFYMLISILGKYK 230

Query: 311 MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXP 370
              ++ P +  L   + +L  + ++ +P+L+ HF++++   ++YA               
Sbjct: 231 FSGLYLPGLPLLNTHLEKLRKIFKKRIPNLYNHFRNENVDETMYASQWFMTIFAYSFNLD 290

Query: 371 LACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFM 430
              RI D+F  EG++++FK+++A+L + KN L +   E+IL +  K  P     +    +
Sbjct: 291 AVARIWDLFFLEGVDLIFKISIAILKILKNSLFNQSFENIL-HTLKTAPYTININD--II 347

Query: 431 NLAYSVKVNPKK 442
             A S K+N K+
Sbjct: 348 QCALSFKLNYKE 359


>UniRef50_Q19101 Cluster: Putative uncharacterized protein F01G12.6;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein F01G12.6 - Caenorhabditis elegans
          Length = 466

 Score =  170 bits (414), Expect = 1e-40
 Identities = 113/379 (29%), Positives = 192/379 (50%), Gaps = 26/379 (6%)

Query: 467 LRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRRANVDMQQR 526
           LR ENRLL+QR+              V+GQV+ A+  E    +  E+  LR  N D+ ++
Sbjct: 19  LRTENRLLRQRIDYLEAESSALADRLVKGQVNLAQEAENYINIAHELNKLRDMNSDVHRK 78

Query: 527 LAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXXX 586
           L  A + IR  E++ A  ++   +    +  S  +H      LQ                
Sbjct: 79  LEGAYETIR--ELSSARRDNIMDTGTQVDDTSMIEH---IHSLQQELIEAHTRQADSENT 133

Query: 587 XXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSE 646
                  + ELE  NK L       +VA LQ+ELI+VK+REAE++L+LK++RQR++EL +
Sbjct: 134 LRDAKLRVSELEMANKRLLENEPSEDVAGLQEELISVKMREAESSLALKEMRQRLAELEQ 193

Query: 647 SWQRHLQEHKQEAPAAPVQSNVVSDIMAT---PKKLLRAWEGRSA--------------- 688
            W +++     +  +A ++    S+  +T   P   L +   R A               
Sbjct: 194 HWAKYVHVRAFDPSSASIEKESTSEAHSTQQQPSPPLTSARARLAKITASLIGGSTEETD 253

Query: 689 ---DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLREN 745
               + +L+++LM  RI+E + L ELKE+R KVMELETQ  V TNQL+RQDEE + +RE+
Sbjct: 254 NCISVRELEDQLMGVRIKEADTLAELKEMRQKVMELETQNHVCTNQLKRQDEEMKRVRED 313

Query: 746 LDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLK 805
            +  +++ + L+ + ++ + K  + ES+     +   ++  E  Q I +L++ +S+ +LK
Sbjct: 314 SEVLVKKRKELEDQLKDEKEKLDNKESEFNEGRINDRLKYSEAMQTIQDLQSSISQLELK 373

Query: 806 NEVMATEGELRNNNMDDSD 824
                T+ +LR +++ D D
Sbjct: 374 KAEKWTQNQLRGSSVCDLD 392


>UniRef50_Q9VNG9 Cluster: CG1093-PA, isoform A; n=8; Diptera|Rep:
            CG1093-PA, isoform A - Drosophila melanogaster (Fruit
            fly)
          Length = 1379

 Score =  167 bits (406), Expect = 1e-39
 Identities = 103/339 (30%), Positives = 171/339 (50%), Gaps = 16/339 (4%)

Query: 195  VRQGVPHHFRGIVWQLLA---GVDTSP-EKKLYASY-------IKAKSACEKVIRRDIAR 243
            +R GVP   RG VW  LA    ++T+P + K + ++       +K  +  +  I  D+ R
Sbjct: 740  IRTGVPRSKRGDVWTFLAEQHSMNTAPVDTKRFPNFNTPYHMLLKHLTEHQHAIFIDLGR 799

Query: 244  TYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLV 303
            T+P H F+K+  GLGQ SLFN++KAYS+ D E+GYCQG GFI G+LL+   E  +F +L 
Sbjct: 800  TFPNHQFYKDPLGLGQLSLFNLLKAYSILDPELGYCQGLGFICGVLLLHCDEANSFQLLK 859

Query: 304  KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
             +M +  MR  + P M +  L ++QL  LV++ LPDL+V       S +LYA        
Sbjct: 860  HLMFRRNMRTKYLPDMKKFQLQLYQLSRLVKDHLPDLYVWLDQNDVSPTLYAAPWILTVF 919

Query: 364  XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLD-MESILKYIQKELPLKA 422
                      R+ D+   E  +++FK A+ALL++ K  LL+ D  E I+ Y++  +P   
Sbjct: 920  SSQFPLGFVARVFDLLFLESSDVIFKFAIALLSVHKQQLLAKDNFEEIMDYLKTVVPKME 979

Query: 423  EADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK---TKEQGDIAVLRCLRQENRLLKQRVX 479
                   M L +S+ +  K++ + + EY V++   T     + +L   + +N+ L+Q++ 
Sbjct: 980  HTCMEQIMKLVFSMDIG-KQLAEYKVEYNVLQEEITTTNHHLEMLNREKTQNQHLEQQLQ 1038

Query: 480  XXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR 518
                            Q      + +  +L+  +Q L R
Sbjct: 1039 FAQSSIAQLETTRSSQQAQITTLQSQVQSLELTIQTLGR 1077


>UniRef50_Q86TI0 Cluster: TBC1 domain family member 1; n=33;
            Euteleostomi|Rep: TBC1 domain family member 1 - Homo
            sapiens (Human)
          Length = 1168

 Score =  165 bits (401), Expect = 5e-39
 Identities = 113/394 (28%), Positives = 192/394 (48%), Gaps = 16/394 (4%)

Query: 167  EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------DT 216
            +++ ++W +++S    S+ K   + +   V QGVP H RG +W+ LA             
Sbjct: 768  KEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQ 827

Query: 217  SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
             P+   Y   +K  ++ +  I  D+ RT+P H +F  + G GQ SL+N++KAYSL D+EV
Sbjct: 828  QPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEV 887

Query: 277  GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
            GYCQG  F+ G+LL+ M EEEAF +L  +M    +R  ++P M  L + M+QL  L+ + 
Sbjct: 888  GYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 947

Query: 337  LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
              DL+ H +      SLYA                  R+ D+   +G E++FKVAL+LL 
Sbjct: 948  HRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLG 1007

Query: 397  LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
              K  +L  + +E+I+ +I+  LP          +N  + + +  K+++  E EY V++ 
Sbjct: 1008 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ- 1065

Query: 456  KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
            +E  D + L   ++ ++L K                 V  G++   E   E   L  E  
Sbjct: 1066 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-S 1123

Query: 515  ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQ 548
             L++A + ++   +  L  +  L    AE + R+
Sbjct: 1124 KLKQAMLTLELERSALLQTVEELRRRSAEPSDRE 1157


>UniRef50_Q6CR16 Cluster: Similar to sgd|S0006170 Saccharomyces
           cerevisiae YPL249c; n=1; Kluyveromyces lactis|Rep:
           Similar to sgd|S0006170 Saccharomyces cerevisiae YPL249c
           - Kluyveromyces lactis (Yeast) (Candida sphaerica)
          Length = 707

 Score =  163 bits (397), Expect = 1e-38
 Identities = 100/317 (31%), Positives = 167/317 (52%), Gaps = 15/317 (4%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           W  W +LV N+    K  ++ +   V +G+P   RGI+WQLL   +    ++LY S +  
Sbjct: 265 WPFWSKLVHNFSDIVKDDSKKLETEVGKGIPTQVRGIIWQLLTSSNYKEMEELYCSLLLL 324

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
           +S  EK I+RD++RT     F  E      +SLF+V+KAYSL+D  VGY QG GFI   L
Sbjct: 325 ESPHEKAIKRDLSRT----KFIPEGK---TDSLFSVLKAYSLYDPPVGYTQGMGFIATTL 377

Query: 290 LMQMPEE-EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           ++   EE +AF++L K+M+ + +RD+F P M  L L ++Q + L++E  P L+ H   Q 
Sbjct: 378 ILNCEEEWQAFSLLTKLMKVYGLRDLFLPGMPGLMLKLYQFDTLLEENDPQLYNHLIRQG 437

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
             ++++A                  RIMD+ + EGIE + K +L L+     +L+ L  +
Sbjct: 438 IRSTMFATQWFLTMFAYKFPLEFVLRIMDIVILEGIESMLKFSLTLMLKNSRNLIILSFD 497

Query: 409 SILKYIQKEL-------PLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI 461
           S+L +++++L           E D   F++ +  +K+ P ++++  KEY  I   E    
Sbjct: 498 SLLDFLKEDLFQHYASKENPEEYDIDRFISDSLEIKLTPLQLERYVKEYDEIHKLETEKE 557

Query: 462 AVLRCLRQENRLLKQRV 478
                 R +NR L++ +
Sbjct: 558 QQYEEQRIKNRQLQKEL 574


>UniRef50_O60343 Cluster: TBC1 domain family member 4; n=21;
            Euteleostomi|Rep: TBC1 domain family member 4 - Homo
            sapiens (Human)
          Length = 1298

 Score =  163 bits (397), Expect = 1e-38
 Identities = 91/303 (30%), Positives = 159/303 (52%), Gaps = 11/303 (3%)

Query: 166  EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA---------GVDT 216
            ++++   W + + N  ++ +   + +  L+++GVP   RG +WQ LA             
Sbjct: 886  QKEVLITWDKKLLNCRAKIRCDMEDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNKQ 945

Query: 217  SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
             P    Y   +K  +A +  I  D+ RT+P H +F  + G GQ SLFN++KAYSL D+EV
Sbjct: 946  QPPDISYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEV 1005

Query: 277  GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
            GYCQG  F+ G+LL+ M EE+AF +L  +M     R  ++P M  L + M+QL  L+ + 
Sbjct: 1006 GYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDY 1065

Query: 337  LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
              DL+ H +    S SLYA                  R+ D+   +G E++FKVAL+LL+
Sbjct: 1066 HRDLYNHLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLS 1125

Query: 397  LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
              +  ++  +  E+I+++++  LP    ++    +   + + ++ K++   E EY V++ 
Sbjct: 1126 SQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDIS-KQLHAYEVEYHVLQD 1184

Query: 456  KEQ 458
            + Q
Sbjct: 1185 ELQ 1187


>UniRef50_O97790 Cluster: TBC1 domain family member 1; n=4;
           Eutheria|Rep: TBC1 domain family member 1 - Bos taurus
           (Bovine)
          Length = 556

 Score =  163 bits (397), Expect = 1e-38
 Identities = 110/395 (27%), Positives = 191/395 (48%), Gaps = 16/395 (4%)

Query: 167 EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG---------VDT 216
           +++ ++W +++S    S+ K   + +   V QGVP H RG +W+ LA             
Sbjct: 156 KEVTTVWEKILSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHPFPCKQ 215

Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
            P+   Y   +K  ++ +  I  D+ RT+P H ++  + G GQ SL+N++KAYSL D+EV
Sbjct: 216 QPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEV 275

Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
           GYCQG  F+ G+LL+ M EEEAF +L  +M    +R  ++P M  L + M+QL  L+ + 
Sbjct: 276 GYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 335

Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
             DL+ H +      SLYA                  R+ D+   +G E++FKVAL+LL 
Sbjct: 336 HRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLG 395

Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
             K  +L  + +E+I+ +I+  LP          ++  +   ++ K+++  E EY V++ 
Sbjct: 396 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFETDIS-KQLQAYEVEYHVLQ- 453

Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
           +E  D + L   ++ ++L K                 V  G++   E   E         
Sbjct: 454 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATVEKLLTSE--S 511

Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQS 549
            L++A + ++   +  L  +  L    AE  S++S
Sbjct: 512 KLKQATLALELERSALLQTVEQLRRQTAELGSQES 546


>UniRef50_A5DNI2 Cluster: Putative uncharacterized protein; n=2;
           Saccharomycetales|Rep: Putative uncharacterized protein
           - Pichia guilliermondii (Yeast) (Candida guilliermondii)
          Length = 655

 Score =  163 bits (396), Expect = 2e-38
 Identities = 117/428 (27%), Positives = 205/428 (47%), Gaps = 38/428 (8%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           W  W  +V+++ES  +  +  +   +  G+P   RGIVWQL+A       ++ Y +    
Sbjct: 201 WEFWANVVNDYESVVQNNSHALHSKIAAGIPKEVRGIVWQLVAQSKNYELEEFYLTLKSE 260

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQ-ESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
            S  EK I+RD+ RT     F+   D + + E L+NV+KAYSL D +VGY QG  F+   
Sbjct: 261 TSIHEKAIKRDLTRT----SFYTAVDAVSKGEDLYNVIKAYSLFDPDVGYTQGMIFVAVP 316

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           L+M M + E F +LV +M+ +R+RD+F P M  L   ++Q + L+++  P L+ H   Q 
Sbjct: 317 LIMNMTDSECFCLLVTMMKDYRLRDLFCPDMRGLHRQLYQFDRLLEQNSPLLYNHLVKQG 376

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
             +S+YA               +  RI D+ ++ GIE + K A+ L+   +N LLSL  +
Sbjct: 377 IKSSMYASQWFLTFFAYKFPLEIVLRIYDIVITHGIEALLKFAVNLMLQNENKLLSLKFD 436

Query: 409 SILKYIQKEL----------------PLKAEADQAAFMNL------AYSVKVNPKKMKKL 446
            +L++++  L                  K +   +++ NL      A ++KV+   + + 
Sbjct: 437 KLLEFLKDHLFNRYVNDEFVDERRFSLRKRQGSSSSYYNLDSMVEDAMAIKVSMVDLAQF 496

Query: 447 EKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEET 506
           E+E+  I   E+     +  LR EN  L+  +               R  VD  +   +T
Sbjct: 497 EREFDAIYASEKHRAEEIDELRHENGRLRHDIKALEHQFSVLN----RDHVDIVQKMVDT 552

Query: 507 FALDREVQALRRANVDMQQRLAVALDEIRSLE--MTIAENNSRQSSLEGTESASGQKH-- 562
             +  E+++    N D+Q+ +     ++  LE  M     +S +S+L+  +S +  ++  
Sbjct: 553 KVMIPEIES---ENDDLQKAITQLRADLEELEAKMKAPSVSSSESTLDALKSPAIPQNIE 609

Query: 563 EELARCLQ 570
           EE+ R LQ
Sbjct: 610 EEIQRLLQ 617


>UniRef50_UPI0000F1EF08 Cluster: PREDICTED: similar to TBC1 domain
            family, member 4,; n=1; Danio rerio|Rep: PREDICTED:
            similar to TBC1 domain family, member 4, - Danio rerio
          Length = 1251

 Score =  163 bits (395), Expect = 3e-38
 Identities = 96/301 (31%), Positives = 154/301 (51%), Gaps = 16/301 (5%)

Query: 167  EDLWSLWGRLVSN---WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDT------- 216
            ++L +LW R +S+    + +W +    +   V QGVP   RG VW LL+           
Sbjct: 840  KELQALWDRKLSSPCRTKVQWNKEE--IHSAVCQGVPKSRRGEVWLLLSQQHRLRQRLPH 897

Query: 217  --SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDR 274
               P +  +   +K  +A +  I  D+ RT+P H +F  + G GQ SL+N++KAYSL D 
Sbjct: 898  RQQPPETPFQDLLKQLTAQQHAILVDLGRTFPTHQYFSAQLGAGQLSLYNLLKAYSLLDT 957

Query: 275  EVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQ 334
            EVGYCQG  F+ GLLL+ M EE++F  L  +M    +R  ++P M  L + M+QL  L+ 
Sbjct: 958  EVGYCQGISFVAGLLLLHMSEEQSFDTLKFLMYDLGIRRQYRPDMISLQIQMYQLSRLLH 1017

Query: 335  ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
            +   +L+ H        SLYA                  RI D+   +G E++FKVAL L
Sbjct: 1018 DYHRNLYSHLDEHEICPSLYAAPWFLTLFASQFPLGFVARIFDLLFVQGTEVIFKVALCL 1077

Query: 395  LTLGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVI 453
            L+  + ++L  D  ESI+ Y++  +P    +     +  A  + ++ K+++  E EY V+
Sbjct: 1078 LSSHEGEILECDSFESIVDYLKSTIPTLTHSQMEEIITKAIEMDIS-KQLQAYEVEYHVL 1136

Query: 454  K 454
            +
Sbjct: 1137 Q 1137


>UniRef50_A3LZ48 Cluster: Predicted protein; n=2;
           Saccharomycetaceae|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 641

 Score =  160 bits (389), Expect = 1e-37
 Identities = 81/250 (32%), Positives = 142/250 (56%), Gaps = 5/250 (2%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           W  W ++V+++ +     +  + DL+  G+P  FRGI+WQL++       ++ Y S    
Sbjct: 185 WDFWTQIVNDYGAVIHNDSNKLNDLISSGIPKEFRGIIWQLVSKSKNFQLEEFYISLKAE 244

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQ-ESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
            S  EK I+RD++RT     FF   + + + E LFNV+KAYSL+D +VGY QG  FI   
Sbjct: 245 ASIHEKSIKRDLSRT----SFFTNVEAVNKGEELFNVIKAYSLYDPDVGYTQGMIFIAVP 300

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           L+M M + E F +LV +M+++R+RD+F P M  L L +++ + +++   P L+ H   Q 
Sbjct: 301 LIMNMNDAECFCLLVTLMKEYRLRDLFCPEMKGLHLLLYEFDRVLENYSPLLYNHLVKQG 360

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
             +S+YA               +  RI D+ +++GIE + K A+ L+   + +LL+L  +
Sbjct: 361 IKSSMYATQWFLTFFAYKFPLDIVLRIYDIIITQGIESILKFAVNLMIKNEANLLALKFD 420

Query: 409 SILKYIQKEL 418
            +L++++ +L
Sbjct: 421 KLLEFLKDKL 430


>UniRef50_Q3TAQ5 Cluster: Activated spleen cDNA, RIKEN full-length
           enriched library, clone:F830004G22 product:TBC1 domain
           family, member 4, full insert sequence; n=3;
           Murinae|Rep: Activated spleen cDNA, RIKEN full-length
           enriched library, clone:F830004G22 product:TBC1 domain
           family, member 4, full insert sequence - Mus musculus
           (Mouse)
          Length = 513

 Score =  159 bits (387), Expect = 2e-37
 Identities = 89/299 (29%), Positives = 155/299 (51%), Gaps = 11/299 (3%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA---------GVDT 216
           ++++   W + + N  ++ K   + +   +++GVP   RG +WQ LA             
Sbjct: 101 QKEILIAWDKKLLNCRTKIKCDMEDIHTSLKEGVPKSRRGEIWQFLALQYRLRHRLPNKH 160

Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
            P    Y   +K  +A +  I  D+ RT+P H +F  + G GQ SLFN++KAYSL D+EV
Sbjct: 161 QPPDTSYKELLKQLTAQQHTILVDLGRTFPTHPYFSVQLGAGQLSLFNLLKAYSLLDKEV 220

Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
           GYCQG  F+ G+LL+ M EE+AF +L  +M     R  ++P M  L + M+QL  L+ + 
Sbjct: 221 GYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDY 280

Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
             +L+ H +    S SLYA                  R+ D+   +G E++FKVAL+LL+
Sbjct: 281 HRELYNHLEENEISPSLYAAPWFLTLFASQFPLGFVARVFDIIFLQGTEVIFKVALSLLS 340

Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK 454
             +  ++  +  E+I+++++  LP     +    +   + + ++ K++   E EY V++
Sbjct: 341 SQEALIMECENFENIVEFLKSTLPDMNTTEMEKIITQVFEMDIS-KQLHAYEVEYHVLQ 398


>UniRef50_Q6CEY1 Cluster: Similarities with tr|AAH43775 Xenopus
           laevis; n=1; Yarrowia lipolytica|Rep: Similarities with
           tr|AAH43775 Xenopus laevis - Yarrowia lipolytica
           (Candida lipolytica)
          Length = 597

 Score =  159 bits (387), Expect = 2e-37
 Identities = 91/260 (35%), Positives = 149/260 (57%), Gaps = 13/260 (5%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA---------GVDT 216
           ++DL S W   + ++     R   +  D+VR GVP   RG +W+ +A           D 
Sbjct: 82  QKDL-SFWSAAMVSFNDCATRIPHYSCDMVRGGVPPALRGDIWKSMAYTSGGDCGSSEDI 140

Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
           +  K LY S     +   K+I RD+ RT+PE D F+E++G GQ  +  V++AYS +D +V
Sbjct: 141 ASLKYLYDSLANEWTPYVKIIGRDLHRTFPEIDLFREQEGKGQIMMGKVLRAYSAYDMQV 200

Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
           GYCQG  F+VG LL+ M + +AF VLVK+++ + +R MF   MA L L MFQ E+L+++ 
Sbjct: 201 GYCQGLTFLVGPLLLHMDDCDAFCVLVKLLENYDLRSMFAADMAGLHLKMFQFESLLEQQ 260

Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGI-EIVFKVALALL 395
           LP++H H +S + +T +YA              P+  RI D+   EG+ E + + A+A+L
Sbjct: 261 LPEIHAHLKSLNINT-IYASQWFMSLFAVTCPLPMLVRIYDLMFLEGVTETLMRTAMAIL 319

Query: 396 TLGKNDLLSL-DMESILKYI 414
              K ++L++ + E +L+++
Sbjct: 320 KRNKYNILNMTEEEDVLQHL 339


>UniRef50_A5DY91 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 661

 Score =  159 bits (387), Expect = 2e-37
 Identities = 88/279 (31%), Positives = 149/279 (53%), Gaps = 7/279 (2%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           W  W  +V +++     +   + +L+ QG+P   RGI+WQ++     S  + LY S    
Sbjct: 151 WDFWTWVVDDYDYIVNNKLDQLNELIAQGIPSEIRGIIWQIVTKSKDSNLEDLYRSLKHE 210

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQ-ESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
            S  EK I+RD+ RT     FF   D + + + L+NV+KAYSL+D +VGY QG  FI   
Sbjct: 211 SSIHEKAIKRDLTRT----SFFTNIDAVNKADELYNVIKAYSLYDPDVGYTQGMIFIAVP 266

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           L+M M E E F +LV +M+++++R++F P M  L L ++Q + L+ + +P L+ H   Q 
Sbjct: 267 LIMNMHESECFCLLVLLMKEYQLRELFCPEMKGLHLLLYQFDCLLAKNVPTLYNHLVKQG 326

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
             +S+YA               +  RI DV ++EG+E + K A+ L+   +  LL+L  +
Sbjct: 327 IKSSMYASQWFLTFFAYKFPLDIVLRIYDVIITEGMESILKFAVNLMVQNEASLLALSFD 386

Query: 409 SILKYIQKELPLKAEADQAAFMNLAYSVKV-NPKKMKKL 446
            +L++++ +L      + A   N  +  KV +P K   +
Sbjct: 387 KLLEFLKDKL-FNVYVNPAFIKNTKHDSKVLSPTKFSAI 424


>UniRef50_Q0U1N8 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 962

 Score =  159 bits (386), Expect = 3e-37
 Identities = 99/311 (31%), Positives = 156/311 (50%), Gaps = 8/311 (2%)

Query: 109 LLAKLEEENRRIEADAK---NASLTTVHSRKXXXXXXXXXXXXXXXXHEVETRPTPGTNG 165
           LLA+LE+EN  + +D+K    AS     SR                  +V     P    
Sbjct: 156 LLARLEQENNALMSDSKAGIKASRARSQSRPPSFGQLKRLVQEDEAS-QVRFSQLPSPPP 214

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYAS 225
             +L   W  LV ++    +R      + +R G+P   RG+VWQ  +G      +  Y +
Sbjct: 215 MTEL-EFWAALVRDYPQTVQRLPTLSLNKIRGGIPAPLRGVVWQSASGSREKLIEDQYDT 273

Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
                S  E +I +D+ R++P  + FK+ +G GQ+ L  V+K +SL+D +VGYCQG GF+
Sbjct: 274 LCGESSPHENIINKDLGRSFPGVEMFKDPEGEGQKMLGRVLKCFSLYDHKVGYCQGLGFL 333

Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           VG LLMQM ++EAF VLV++M+ + +R  F P ++ L L ++Q + L+ + +P L  H  
Sbjct: 334 VGPLLMQMGDKEAFCVLVRLMEDYDLRSCFLPDLSGLHLRIYQFQQLLAQHMPQLAKHLD 393

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGI-EIVFKVALALLTLGKNDLLS 404
                 S Y               P+  RI DV  +EG  E + +VALAL+   +  LLS
Sbjct: 394 ELGIE-SAYLSQWFLSFFAVTCPLPMLFRIYDVLFAEGASETIMRVALALMKRNEQKLLS 452

Query: 405 L-DMESILKYI 414
           L + E +++ +
Sbjct: 453 LSEFEDVMQLL 463


>UniRef50_Q54KE5 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1076

 Score =  158 bits (383), Expect = 7e-37
 Identities = 95/286 (33%), Positives = 154/286 (53%), Gaps = 14/286 (4%)

Query: 159  PTPGTNGEEDLWSLWGRLVSNW----ESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV 214
            P  G N EE       ++   W    + E    +  +R+ + +G+P   RG+ W+ L   
Sbjct: 747  PNGGLNDEEVKTKKMEKIEKKWVKLIKFEVSFTSHKIRERLPKGIPSSVRGMAWKKLFET 806

Query: 215  DTSPEKKLYASYIK--AKSACEKV---IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAY 269
             TS + K   +Y +   K   + +   I++D+ RT+P+H FF+EK G+GQ+ L N++ A+
Sbjct: 807  -TSIKNKAKVTYAELLTKPLPQGIHIQIQKDLDRTFPKHSFFQEKGGMGQQILSNILTAF 865

Query: 270  SLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQL 329
            S+++ EVGYCQG GFI  LLL+ M EE+AF  L+++ +++ M +M+KP    L  C   L
Sbjct: 866  SIYNPEVGYCQGMGFITCLLLIYMAEEDAFWSLIQLTERYGMSEMWKPDFPYLQTCFSIL 925

Query: 330  ENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFK 389
            +NL++   P L +HFQ Q+  T L+A                  RI D+FL +G+ I+F 
Sbjct: 926  DNLLEAHFPQLFLHFQKQNVFTPLFASQWFICLLIYNLPFSYIVRIWDLFLYDGLVIIFA 985

Query: 390  VALALLTLGKNDLLSLDMESI---LKYIQKELPLKAEADQAAFMNL 432
              L+L  + ++ LL ++ E I   LK+   E     +AD + FM L
Sbjct: 986  SCLSLFKIYEDHLLKMEFEEIVNLLKFSNGE-DKNIKADVSTFMKL 1030


>UniRef50_UPI00015B48C3 Cluster: PREDICTED: similar to Pollux
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to Pollux protein - Nasonia vitripennis
          Length = 1296

 Score =  157 bits (380), Expect = 2e-36
 Identities = 99/301 (32%), Positives = 152/301 (50%), Gaps = 16/301 (5%)

Query: 169 LWSLWGRLVSNWES-EWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKL----- 222
           L  +W  LVS       K  +Q +   ++QGVP   RG VWQ LA      +  L     
Sbjct: 652 LVEVWDLLVSKESRISTKCDSQMLLQAIKQGVPRGKRGEVWQFLAEQFCMKQPPLDSRDF 711

Query: 223 ------YASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
                 Y   +K  ++ +  I  D+ RT+P H +F    G GQ +LFN++KAYSL D EV
Sbjct: 712 PNYNTPYELLLKQLTSQQHAILIDLGRTFPNHPYFSSPLGPGQLALFNLLKAYSLLDHEV 771

Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
           GYCQG  F+ G+LL+ M E+ AF +L  +M +  +R ++ P MA L L ++QL  L+ + 
Sbjct: 772 GYCQGLSFVAGVLLLHMSEDLAFFLLRHLMFRRGLRKLYLPDMAALQLHLYQLSRLLHDR 831

Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
           LP ++ HF     S +LYA                  R+ D+   E  E++F+VALALL 
Sbjct: 832 LPAIYNHFDKHEVSPTLYAAPWLLTLFASQFPLGFVTRVFDLLFLESSEVIFRVALALLE 891

Query: 397 LGKNDLLSLD-MESILKYIQKELPL--KAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVI 453
             ++ LL  D  E I++Y++ ++P   K   D+     + Y      K++ +   EY V+
Sbjct: 892 EHQDQLLCCDSFEEIMEYLKTKVPAVDKVTLDR-VMKRVFYPDMEMAKQLNEYRVEYQVL 950

Query: 454 K 454
           +
Sbjct: 951 Q 951


>UniRef50_UPI0000519F7A Cluster: PREDICTED: similar to pollux
           CG1093-PA, isoform A; n=1; Apis mellifera|Rep:
           PREDICTED: similar to pollux CG1093-PA, isoform A - Apis
           mellifera
          Length = 1249

 Score =  155 bits (375), Expect = 7e-36
 Identities = 99/323 (30%), Positives = 159/323 (49%), Gaps = 14/323 (4%)

Query: 168 DLWSLWGRLVSNWES-EWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--------VDTSP 218
           +L  +W  LVS       K  NQ +   ++QGVP   RG VWQ LA         +DT  
Sbjct: 610 ELVEVWDLLVSKESRVSTKCDNQMLLQAIKQGVPKGKRGEVWQFLAEQFCLKQPPIDTRD 669

Query: 219 EKKLYASY---IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
                  Y   +K  ++ +  I  D+ RT+P H +F    G GQ +LFN++KAYSL D E
Sbjct: 670 FPNYNTPYDLLLKQLTSQQHAILIDLGRTFPNHPYFSSPLGPGQLALFNLLKAYSLLDHE 729

Query: 276 VGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQE 335
           VGYCQG  F+ G+LL+ M E++AF +L  +M +  +R ++ P MA L L ++QL  L+ +
Sbjct: 730 VGYCQGLSFVAGVLLLHMSEDQAFFLLRHLMFRRGLRKLYLPDMAALQLYLYQLSRLLHD 789

Query: 336 LLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
            L  ++ HF     S +LYA                  R+ D+   E  E++F+V++ALL
Sbjct: 790 RLAPIYNHFDKHEVSPTLYAAPWLLTLFASQFPLGFVTRVFDLLFLESTEVLFRVSMALL 849

Query: 396 TLGKNDLLSLD-MESILKYIQKEL-PLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVI 453
              ++ LL  D  E I++Y++  +  +  +        + Y  +   K++ +   EY V+
Sbjct: 850 QEHQDQLLKCDSFEEIMEYLKTRVSAVDKDILDRVMKRVFYPDQEITKQLNEYRVEYQVL 909

Query: 454 KTKEQGDIAVLRCLRQENRLLKQ 476
           + +       +  L +   L KQ
Sbjct: 910 QEEMMSVKPQIESLEKFKLLNKQ 932


>UniRef50_UPI0000660373 Cluster: TBC1 domain family member 1.; n=1;
            Takifugu rubripes|Rep: TBC1 domain family member 1. -
            Takifugu rubripes
          Length = 1083

 Score =  154 bits (373), Expect = 1e-35
 Identities = 91/267 (34%), Positives = 138/267 (51%), Gaps = 11/267 (4%)

Query: 197  QGVPHHFRGIVWQLLA---------GVDTSPEKKLYASYIKAKSACEKVIRRDIARTYPE 247
            QGVP   RG VW+ L+              P+   Y   +K  S+ +  I  D+ RT+P 
Sbjct: 745  QGVPKQHRGEVWKFLSEQHLLRQTVSSQPPPDNTAYKELLKQVSSEQHAILIDLGRTFPT 804

Query: 248  HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
            H +F+E  G GQ SL+NV+ AYS+ D EVGYCQG  F+ G+LL+ + EE+AF +L  +M 
Sbjct: 805  HPYFEESMGPGQLSLYNVLSAYSVLDPEVGYCQGLCFVTGVLLLHLEEEDAFNMLKFLMF 864

Query: 308  QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
               +R  +KPSM  + + M+QL  L+ +   DL  H + Q  + SLYA            
Sbjct: 865  VLGLRQQYKPSMTAVQIQMYQLSRLLHDYHKDLQCHLEQQDIAPSLYAPPWFLTNFASQY 924

Query: 368  XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLD-MESILKYIQKELPLKAEADQ 426
                  R+ D+   +G E++FKV L+LL   K  ++  D +ESI+  I+ ELP       
Sbjct: 925  PLGFVARVFDMLFLQGPEVIFKVGLSLLGSHKLLIMQHDSLESIVDVIKTELPNLGLVQM 984

Query: 427  AAFMNLAYSVKVNPKKMKKLEKEYTVI 453
               +N    + +  K+++  E EY V+
Sbjct: 985  EKTVNQVCEMDLT-KQLQAYEVEYQVL 1010


>UniRef50_Q174R1 Cluster: Rab6 gtpase activating protein, gapcena;
            n=1; Aedes aegypti|Rep: Rab6 gtpase activating protein,
            gapcena - Aedes aegypti (Yellowfever mosquito)
          Length = 1318

 Score =  153 bits (372), Expect = 2e-35
 Identities = 92/300 (30%), Positives = 158/300 (52%), Gaps = 18/300 (6%)

Query: 195  VRQGVPHHFRGIVWQLLAG--------VDTSPEKKLYASY---IKAKSACEKVIRRDIAR 243
            ++ GVP   RG VW  LA         VD S     +  Y   +K+ +  +  I  D+ R
Sbjct: 770  IKNGVPRAKRGEVWMFLANQHSFNTAPVDVSNFPNYHTPYQTLLKSLTEHQHAIFIDLGR 829

Query: 244  TYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLV 303
            T+P+H ++K+  G+GQ SLFN++KAYS+ D E+GYCQG GFI  +LL+ + E +AF +L 
Sbjct: 830  TFPDHKYYKDALGVGQLSLFNLLKAYSILDPELGYCQGLGFICAVLLLHLEEADAFNLLK 889

Query: 304  KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
             +M + +MR  + P M +  L ++QL  L+++ +P+L+  F     S +LYA        
Sbjct: 890  HLMFKRQMRAKYLPDMKQFQLQLYQLSRLLKDHIPELYDWFDQHDISPTLYAAPWILTVF 949

Query: 364  XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLD-MESILKYIQKELP-LK 421
                      R+ D+   E  +++F+ A+ALL + K  LL  D  E I+ Y++  +P + 
Sbjct: 950  SSHFPLGFVARVFDLLFLESFDVIFRCAIALLEVHKEQLLQRDNFEEIMNYLKTVVPKID 1009

Query: 422  AEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK---TKEQGDIAVLRCLRQENRLLKQRV 478
            A   +  F N+  S     +++ + + EY V+K   T +   +     +++EN  L+ ++
Sbjct: 1010 ANVMEKVFRNVFKS--DFSRQLIEYQVEYNVLKEEMTSQNHHLENFNRVKEENHQLETQL 1067


>UniRef50_A5AB01 Cluster: Function: GAPCenA is a GTPase activating
           protein for Rab6; n=8; Eurotiomycetidae|Rep: Function:
           GAPCenA is a GTPase activating protein for Rab6 -
           Aspergillus niger
          Length = 902

 Score =  153 bits (371), Expect = 2e-35
 Identities = 94/317 (29%), Positives = 156/317 (49%), Gaps = 17/317 (5%)

Query: 109 LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETR---------P 159
           LLA+LE+EN  +  + K+A  +  H+++                 + + R         P
Sbjct: 135 LLARLEQENNALATNPKSALASKSHAQRVTRPSRAQSLHQIKRLIDEDPRSSLRYSQLPP 194

Query: 160 TPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE 219
            P T  E      W  LV+++    +R      + +R GVP   RG+VW  LAG   +  
Sbjct: 195 PPMTELE-----FWAALVADYPQTAQRLPTLTSNKIRSGVPPPLRGVVWPSLAGARDNTL 249

Query: 220 KKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYC 279
              Y       S  E +I +DI R++P  + F++ +G GQ+ L  V+K +SL+D ++GYC
Sbjct: 250 LTEYQRLCGETSPYEGLIGKDIGRSFPNVEMFRDPNGEGQQMLARVLKCFSLYDTKIGYC 309

Query: 280 QGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPD 339
           QG GF+VG LLM M + EAF VLV++M  + +R  + P ++ L L ++Q +NL+  L P 
Sbjct: 310 QGLGFVVGPLLMHMTDAEAFCVLVRLMDHYDLRTCYLPDLSGLHLRVYQFQNLLARLRPG 369

Query: 340 LHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG-IEIVFKVALALLTLG 398
           L  H +       +Y               P+  RI DV   EG  E + +VAL+L+T  
Sbjct: 370 LFAHLEMLHVE-PVYVSQWFLSFFAVACPLPMLLRIYDVIFLEGACETLMRVALSLMTRN 428

Query: 399 KNDLLS-LDMESILKYI 414
           +  +++  + E +++ +
Sbjct: 429 EKKIMACAEFEDVMQLL 445


>UniRef50_Q4Q0F3 Cluster: Rab-like GTPase activating protein,
           putative; n=5; Trypanosomatidae|Rep: Rab-like GTPase
           activating protein, putative - Leishmania major
          Length = 498

 Score =  152 bits (368), Expect = 5e-35
 Identities = 88/287 (30%), Positives = 147/287 (51%), Gaps = 12/287 (4%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
           W  + ++W     + +  +++  R+G+P  FRG+ WQLL G    +++     +Y +   
Sbjct: 205 WANMAADWNKTNTKMHAKLKERCRKGIPSRFRGVAWQLLMGSFHQLNSEENNGVYVALRD 264

Query: 229 AKSACEK---VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
            K A ++   +I RD+ART+P H  F++  G+GQ  L N++ AY+  D EVGY QG GF+
Sbjct: 265 KKLADKETDVIISRDLARTFPTHVLFQDPGGVGQTFLRNILHAYAGCDPEVGYVQGMGFL 324

Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
           V  L  QM EEE+F  L ++M  ++++MR++F+P    L    +QL+ L+  LLP L   
Sbjct: 325 VAALSTQMAEEESFWALHEMMYNERYKMRELFRPGFPLLQQFFYQLKRLIARLLPRLSKR 384

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
                   S +A                  R+ D+F SEG +I+F+  +ALL   ++ LL
Sbjct: 385 LDELEIQPSFFASQWFLTLFVGHFPFRALLRVWDIFFSEGWKIIFRTGIALLKWEESHLL 444

Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           +L  E  L  ++    L+   D    +  A+ VK    ++ +   EY
Sbjct: 445 TLPFEDTLLALK---GLQDGKDAYELLRRAHRVKFKTAELNRYGDEY 488


>UniRef50_Q9P4Y9 Cluster: Putative uncharacterized protein
           B11B22.030; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein B11B22.030 - Neurospora crassa
          Length = 876

 Score =  151 bits (365), Expect = 1e-34
 Identities = 87/254 (34%), Positives = 132/254 (51%), Gaps = 8/254 (3%)

Query: 170 WSLWGRLVSNWESEWKRRN-QWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIK 228
           W LW  +V    +   R + + +++ + +G+P   RG++WQ+LA       + +Y     
Sbjct: 392 WDLWQTVVYEGPAAVARTSPEQLKEAIAKGIPSAIRGVIWQVLAQSKNEELETVYRDLED 451

Query: 229 AK--SACEKVIRRDI-ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
            +  S  EKVIRRD+ ART   +  F    GL QE LF V KAY+L D  VGY QG  F+
Sbjct: 452 KEMLSRLEKVIRRDLGART--SYSKFAAAQGL-QEGLFGVCKAYALFDEAVGYAQGMNFL 508

Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           V  LL  MPEEEAF +LV++M Q+ +R++F   M  L  C++Q E ++++L P L+ H  
Sbjct: 509 VMPLLFNMPEEEAFCLLVRLMNQYHLRELFIQDMPGLHKCLYQFERILEDLEPALYCHLH 568

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            +  S  LYA               L  RI D+  SEG+  + K  + L+      LL +
Sbjct: 569 RRGISPHLYATQWFLTLFAYRFPLQLVLRIYDLIFSEGLSAIIKFGIVLMQKNATALLGM 628

Query: 406 -DMESILKYIQKEL 418
            DM  +  +++  L
Sbjct: 629 SDMSQLTTFLKDRL 642


>UniRef50_A4R5D7 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 1131

 Score =  150 bits (364), Expect = 1e-34
 Identities = 95/314 (30%), Positives = 158/314 (50%), Gaps = 20/314 (6%)

Query: 109 LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETRPTPGTNGEED 168
           LLA+LE+EN ++  + K+A    +  ++                  + T PTP       
Sbjct: 241 LLARLEQENAKLATNPKSAKARLIDDKRKSRPPSMAQL------RNMVTGPTPSALRYSM 294

Query: 169 L-------WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEK 220
           L          +  LV ++E    R    +   +R+G+P   RG+VW  ++G  D + E+
Sbjct: 295 LPPPPMTDLEFYAALVKDYEQTAARLPTLLSHKIRKGIPPPLRGVVWTSMSGARDVALEE 354

Query: 221 KLYASYIKAKSA-CEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYC 279
           +    Y+  +S+  E +I +D+ R++P  D F+E DG GQ  L  V+K YS++D E+GYC
Sbjct: 355 QF--EYLSGESSPFECIISKDLGRSFPGVDMFREADGEGQRMLGRVLKCYSIYDPEIGYC 412

Query: 280 QGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPD 339
           QG  F+VG LLM MP+++AF VLV++M+ + +R  F P ++ L + ++Q   L+ E LP 
Sbjct: 413 QGLAFLVGPLLMHMPDKQAFCVLVRLMENYDLRSCFLPDLSGLHVRIWQFNQLIHEHLPV 472

Query: 340 LHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG-IEIVFKVALALLTLG 398
           L  H         +Y               P   RI DV  +EG  E + +VAL+L+   
Sbjct: 473 LSSHLDDLQVD-PVYVSQWFLSFFGTAAPLPFLFRIYDVLFAEGSTETLLRVALSLMRKN 531

Query: 399 KNDLLS-LDMESIL 411
           +  LL+  +++ +L
Sbjct: 532 ERRLLACTELDGVL 545


>UniRef50_Q3UWI2 Cluster: 15 days embryo male testis cDNA, RIKEN
           full-length enriched library, clone:8030466D01
           product:ecotropic viral integration site 5, full insert
           sequence; n=11; Euteleostomi|Rep: 15 days embryo male
           testis cDNA, RIKEN full-length enriched library,
           clone:8030466D01 product:ecotropic viral integration
           site 5, full insert sequence - Mus musculus (Mouse)
          Length = 425

 Score =  149 bits (362), Expect = 2e-34
 Identities = 104/351 (29%), Positives = 174/351 (49%), Gaps = 38/351 (10%)

Query: 494 RGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG 553
           +GQV RA+  EE + + RE+  ++       Q+   A  ++   E TI E    +     
Sbjct: 15  KGQVTRAQEAEENYLIKRELATIK-------QQTDAARAKLEQAESTIRELRHHRH---- 63

Query: 554 TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV 613
               S   +E+    L+                       + ++E +N S   +   NN+
Sbjct: 64  WHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPDE---NNI 120

Query: 614 AHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
           A LQ+ELIAVKLREAEA + LK+LRQ+V  L E WQRHL          P + N V++  
Sbjct: 121 ARLQEELIAVKLREAEAIMGLKELRQQVRTLEEHWQRHLARTSGRWKDPP-KKNAVNE-- 177

Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
                              L +ELM+ R+RE E   E++ ++ ++ME+ETQ Q+++NQLR
Sbjct: 178 -------------------LQDELMSIRLREAETQAEIRGMKQRMMEMETQNQINSNQLR 218

Query: 734 RQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
           R ++E   L+E + +   + + L  +  E + + A++E K K E M   +R  +    +A
Sbjct: 219 RAEQEVNSLQEKVCSLSVKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVA 278

Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
           EL+  ++E +++ E    +G+L  N  D +  +REL++Q+AEL  E+  L+
Sbjct: 279 ELQQHIAELEIQKEEGKLQGQL--NRSDSNQYIRELKDQIAELTHELRCLK 327


>UniRef50_A7TDN1 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 938

 Score =  149 bits (361), Expect = 3e-34
 Identities = 82/256 (32%), Positives = 135/256 (52%), Gaps = 9/256 (3%)

Query: 165 GEEDL-WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLY 223
           G  D+ W  W  +V+++ +  +     +  ++  G+P   RGI+WQL+A   +   + LY
Sbjct: 417 GTPDIDWEFWSEVVNDFATVTQENADKLESMITDGIPSEIRGIIWQLIANSKSKEYEDLY 476

Query: 224 ASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
            S +K +S  E +IRRD+ RT     F   +     ESLFNV+K YSL D EVGY QG  
Sbjct: 477 ESLLKLESTEESIIRRDLKRT----TFIPPEK---VESLFNVIKVYSLFDTEVGYTQGMA 529

Query: 284 FIVGLLLMQM-PEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHV 342
           FIV  LL+    E +AF +L+ +M+ + +R+ F P M  L L ++Q + LV+E  P L+ 
Sbjct: 530 FIVTPLLLNCDTEADAFGLLISLMKNYGLREFFLPGMPGLMLMLYQFDRLVEENSPLLYN 589

Query: 343 HFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
           +   Q   +++YA                  RI D+   EG+E + K A+ L+   + ++
Sbjct: 590 YLGRQGIRSTMYATQWFLTFFAYKFPLCFVLRIFDIVFVEGVESILKFAVILMLKNEEEI 649

Query: 403 LSLDMESILKYIQKEL 418
           L+L  + +L +++  L
Sbjct: 650 LNLKFDQLLDFLKTGL 665



 Score = 37.5 bits (83), Expect = 1.6
 Identities = 24/98 (24%), Positives = 49/98 (50%), Gaps = 3/98 (3%)

Query: 677 KKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQD 736
           +KL   +   + + + +  EL+ +R++    L E  ++ L V++L+ Q+     +    +
Sbjct: 798 RKLEHDYTLLNREHITIANELIQSRLKIETILDEKNDMNLTVLDLKRQLAEEIRKQNLPN 857

Query: 737 EEARL---LRENLDAALQRERALQTRQREFQHKYADLE 771
            +A L   L+ +L  A+QR   + T   + Q K +DLE
Sbjct: 858 PDASLPSDLKFDLQQAMQRNEEVMTENMKLQDKVSDLE 895


>UniRef50_Q755I4 Cluster: GTPase-activating protein GYP5; n=1;
           Eremothecium gossypii|Rep: GTPase-activating protein
           GYP5 - Ashbya gossypii (Yeast) (Eremothecium gossypii)
          Length = 829

 Score =  149 bits (361), Expect = 3e-34
 Identities = 84/250 (33%), Positives = 135/250 (54%), Gaps = 8/250 (3%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           W  W  +V+N+ +  K  +  + + V  G+P   RGI+WQL++   +   ++LY   ++ 
Sbjct: 343 WQFWTSVVNNFATVAKNDSAKLEEKVSDGIPKQIRGIIWQLISNSKSKEIRQLYQDLLQI 402

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
            S  EK I+RDI+RT      F   D    ESLFNV+KAYSL D EVGY QG  F+   L
Sbjct: 403 PSEHEKAIQRDISRTK-----FIPVD--KTESLFNVLKAYSLFDPEVGYTQGMAFVTAPL 455

Query: 290 LMQMPEE-EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           L+ + EE +AF +L+K+M+ + +R+ F P M  L L +++ + L++E  P L+ H     
Sbjct: 456 LINVWEEADAFGLLIKLMKNYGLREFFLPDMPGLQLKLYEFDRLLEENSPQLYNHLIRLG 515

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
             +S+YA                  RI+DV   EGIE + K A+ L+   ++ L+ L  +
Sbjct: 516 IRSSMYATQWFLTLFAYKFPLGFVLRILDVIFVEGIESLLKFAVILMLKNESVLVQLKFD 575

Query: 409 SILKYIQKEL 418
            +L +++  L
Sbjct: 576 KLLDFLKDGL 585


>UniRef50_A5K2X7 Cluster: TBC domain containing protein; n=1;
           Plasmodium vivax|Rep: TBC domain containing protein -
           Plasmodium vivax
          Length = 547

 Score =  145 bits (352), Expect = 4e-33
 Identities = 84/280 (30%), Positives = 141/280 (50%), Gaps = 17/280 (6%)

Query: 185 KRRNQWVRDLVRQGVPHHFRGIVWQLLA-GVDTSPEKKL-------------YASYIKAK 230
           K+ + ++++ V++GVP H RG VWQ+L    +   E K              Y  Y+   
Sbjct: 256 KQLDGYIKEEVKRGVPDHLRGFVWQILVQSYEYKKESKFTERNRANGRGRNTYQHYLSIT 315

Query: 231 SACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLL 290
           +  E  I++D+ RTYP+H  FK     GQ+ LFNV+KAYS ++R +GYCQG  FIV   +
Sbjct: 316 NQYETAIKKDMNRTYPKHILFKNNYEQGQQILFNVLKAYSNYNRSLGYCQGMAFIVATFI 375

Query: 291 MQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFS 350
           + + EE+AF +L+ +++++ + D+F   M+ L   ++ L+ L+    P + +H + ++  
Sbjct: 376 LYVNEEDAFFMLIALIEKYHLNDLFSSDMSLLNEDLYILDQLLLLFFPKISLHLKKENVH 435

Query: 351 TSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESI 410
           +S++A                  RI D F       +F+VALA   L +  LL    E I
Sbjct: 436 SSMFASQWFITLFSYSISIVYVVRIWDFFFIHSHSFLFRVALAYFKLQEEALLGESFEGI 495

Query: 411 LKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           L  + K L    E D    ++ A  + + P  + +L  EY
Sbjct: 496 LNRL-KVLSRHVELD--LLIDTALGLDLPPATIARLSAEY 532


>UniRef50_Q7S9U4 Cluster: Putative uncharacterized protein
           NCU06362.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU06362.1 - Neurospora crassa
          Length = 1092

 Score =  142 bits (344), Expect = 4e-32
 Identities = 88/315 (27%), Positives = 155/315 (49%), Gaps = 12/315 (3%)

Query: 109 LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETRPTPGTNGEED 168
           LLAKLE+EN +I  + K+  +  V   K                 ++   PTP       
Sbjct: 187 LLAKLEQENNKIATNPKSVKVAAVE--KVASPGRKPRPPSMAQLRQMVNGPTPPALRYSV 244

Query: 169 L-------WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK 221
           L          +  LV + +    R    + + +R+G+P   RG+VWQ + G      + 
Sbjct: 245 LPPPPMTELEFYMALVKDPKQTAARLPTLLSNKIRKGIPPPLRGVVWQSMCGARDKDLED 304

Query: 222 LYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQG 281
           ++       S  E +I +D+ R++P  + F++ +G GQ  L  V+K +SL+D ++GYCQG
Sbjct: 305 VFERLSGESSPYEGIIGKDLGRSFPGVEMFRDPEGDGQRMLGRVLKTFSLYDTKIGYCQG 364

Query: 282 SGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLH 341
             F+VG LLM MP++ AF VLV++M+ + +R  F P ++ L + ++Q   L+++ LP + 
Sbjct: 365 LAFLVGPLLMHMPDKHAFCVLVRLMENYDLRHCFVPDLSGLHVRIYQFTELLKQHLPVVA 424

Query: 342 VHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGI-EIVFKVALALLTLGKN 400
            H +      + Y               P+  RI DV  +EG  E + +VAL+L+   + 
Sbjct: 425 DHLEDLGVEPA-YVSQWFLSFFAVTCPLPMLFRIYDVIFAEGASETIMRVALSLMRKNEG 483

Query: 401 DLLS-LDMESILKYI 414
            +L+  +ME +++ +
Sbjct: 484 RILACTEMEDVMQLL 498


>UniRef50_Q5VSE2 Cluster: Novel protein; n=6; Euteleostomi|Rep:
           Novel protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 423

 Score =  141 bits (342), Expect = 7e-32
 Identities = 85/253 (33%), Positives = 134/253 (52%), Gaps = 9/253 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASY-IKA 229
           W +++ +WE ++K  ++ VR + + G+P   RG VW LL  +    E+K   Y    I+A
Sbjct: 93  WLKMLKSWE-KYKNSDKLVRRIYK-GIPLQLRGQVWCLLLDIPKIKEEKKDFYEKLKIRA 150

Query: 230 KSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
           +     V  I  D+ RTY  H  F  +  + Q+ LF+V+ AYS+++ EVGYCQG   I  
Sbjct: 151 RGLSPDVRQIDLDVNRTYRNHIMFMHRYDVKQQDLFHVLTAYSVYNTEVGYCQGMSQITA 210

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           LLL+ M EE+AF  LVK++  Q+H M   F P   +L       + ++Q+++P L  H  
Sbjct: 211 LLLIYMNEEDAFWALVKLLSGQRHTMHGFFVPGFPKLMRFQEHHDRILQKMMPKLKQHLD 270

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
           +Q   TSLY                L  RI D+++ EG  ++  ++  +L L K  LL L
Sbjct: 271 NQEVYTSLYTMKWFFQCFLDRTPFTLTLRIWDIYILEGERVLTAMSYTILKLHKKTLLKL 330

Query: 406 DMESILKYIQKEL 418
            ME ++K++Q  L
Sbjct: 331 SMEELVKFLQVTL 343


>UniRef50_Q86AV7 Cluster: Similar to Dictyostelium discoideum (Slime
           mold). Hypothetical 58.0 kDa protein; n=3; Dictyostelium
           discoideum|Rep: Similar to Dictyostelium discoideum
           (Slime mold). Hypothetical 58.0 kDa protein -
           Dictyostelium discoideum (Slime mold)
          Length = 531

 Score =  141 bits (342), Expect = 7e-32
 Identities = 77/282 (27%), Positives = 148/282 (52%), Gaps = 9/282 (3%)

Query: 172 LWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKL--YASYI-K 228
           +W +L+ N+  +    N+ ++  +R G+P   RG +W+  +G      K +  Y  ++ K
Sbjct: 246 IWLQLIQNYTHDNIINNEILKS-IRIGLPKRIRGYIWRFFSGAIELERKNIGVYQHFLGK 304

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
                E  I +DI+RT+P + +F  + G  Q SLF ++KAYS+ D E+GY QG  FI  +
Sbjct: 305 HSEEYEYKISKDISRTFPNNPYFNNEQG--QNSLFRILKAYSIMDPEIGYTQGMSFIAAV 362

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LL +M E E+F     IM+ +++  +F   ++ L   ++ ++ L++ LLP L  HF+   
Sbjct: 363 LLSEMDETESFWTFTSIMKNYKLSTLFCHDLSLLRQYLYVIDRLIETLLPKLFSHFKEIG 422

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
            +  L+A              P++ R++DVF  EG   + +++LA+L + +  L+  + E
Sbjct: 423 VTPVLFASEWISTLFTYNFDLPISKRLLDVFFIEGRFYLHRMSLAILKIYEKQLIEFEFE 482

Query: 409 SILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
             +++++K   L  + D    +  + S+ +    ++  EKE+
Sbjct: 483 DAVEFLKK---LGTQIDPDLLLKTSDSLPLTIPMIESFEKEF 521


>UniRef50_Q12344 Cluster: GTPase-activating protein GYP5; n=3;
           Saccharomyces|Rep: GTPase-activating protein GYP5 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 894

 Score =  141 bits (341), Expect = 9e-32
 Identities = 77/250 (30%), Positives = 133/250 (53%), Gaps = 8/250 (3%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           WS W ++V+++ +      + +   V  G+P   RGI+WQL+A   +   + +Y + +  
Sbjct: 423 WSFWTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMANSKSREMEDIYETLLDT 482

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
           +   E  IRRD+ RT      F  +D +  ESL+ V+K YS++D +VGY QG GFI   L
Sbjct: 483 ECLHEATIRRDLRRTK-----FVAEDKM--ESLYKVIKVYSVYDPDVGYTQGMGFIAAPL 535

Query: 290 LMQMPEE-EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           L+    E E+F +LV +M+ + +R++F P M  L L ++Q + L++E  P L+     + 
Sbjct: 536 LINCENEAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSPSLYNRLIREG 595

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
            S+++YA                  RI D+   EGIE++ K A+ L+   +  L+ L  +
Sbjct: 596 ISSTMYATQWFLTFFAYKFPLEFVLRIFDIVFVEGIEVLLKFAVNLMLKNEETLVKLRFD 655

Query: 409 SILKYIQKEL 418
            +L +++ EL
Sbjct: 656 ELLDFLKDEL 665


>UniRef50_Q7RNT0 Cluster: Plant adhesion molecule 1-related; n=2;
           Plasmodium (Vinckeia)|Rep: Plant adhesion molecule
           1-related - Plasmodium yoelii yoelii
          Length = 515

 Score =  140 bits (338), Expect = 2e-31
 Identities = 87/290 (30%), Positives = 144/290 (49%), Gaps = 27/290 (9%)

Query: 185 KRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-----DTSPEKKLY-----ASYIKAKSACE 234
           K+ N  +++ + +G+P + RG VWQ+L         T  +K +      + YI   + CE
Sbjct: 225 KKINSIIKNEIVKGIPDYLRGFVWQILLQSYVYKDRTYADKDINNNENNSEYINQSNKCE 284

Query: 235 K--------------VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQ 280
           K               I++DI RTYP+H  FK     GQ+ LFNV+KAYS +++++GYCQ
Sbjct: 285 KGYKYYLSITNKYESSIKKDINRTYPKHILFKNNYEKGQKILFNVLKAYSNYNQDLGYCQ 344

Query: 281 GSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDL 340
           G  FIV   ++ M EE++F +L+ ++ ++++ D+F  SM  L   ++ L+ L+    P +
Sbjct: 345 GMAFIVATFILYMNEEDSFYMLIALIDKYKLNDLFSSSMPLLNEYLYILDKLLLHFFPKI 404

Query: 341 HVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKN 400
           + H + ++  +S+YA                A RI D F       +FKVALA   L + 
Sbjct: 405 YNHLEKENVHSSMYASQWFITLFSYNINILYAIRIWDFFFIHNYTFLFKVALAFFKLQEE 464

Query: 401 DLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           ++L    E IL  + K L    E D    +  A  +K+    + K+  EY
Sbjct: 465 EILKESFEEILNRL-KVLSKHVELD--VLLKTALDIKIKNGLITKIISEY 511


>UniRef50_A2QJ75 Cluster: Complex: human GAPCenA interacts with
           Rab6; n=1; Aspergillus niger|Rep: Complex: human GAPCenA
           interacts with Rab6 - Aspergillus niger
          Length = 782

 Score =  138 bits (334), Expect = 6e-31
 Identities = 85/260 (32%), Positives = 133/260 (51%), Gaps = 14/260 (5%)

Query: 170 WSLWGRLVSNWESEWKRRNQ-WVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI- 227
           W LW +LV+N     K  N   +   +++G+P   RG++WQ+LA       +++Y   + 
Sbjct: 332 WELWQQLVNNGAQALKGANSDELNAAIKRGIPQTIRGVIWQVLADSRNPELEEVYRELVA 391

Query: 228 ------KAKSACEKVIRRDI-ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQ 280
                 K  S  EK IRRD+ ART     F  + +   QE LF + KAY+L+D  VGY Q
Sbjct: 392 RGTDKEKQSSPNEKTIRRDLGARTSYSRYFVSQGN---QEGLFGLCKAYALYDEAVGYAQ 448

Query: 281 GSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDL 340
           G  FIV  LL  M E EAF +LVK+M Q+ +R++F   M  L   ++  E L++++ P L
Sbjct: 449 GMNFIVMPLLFNMDEAEAFTLLVKLMNQYGLRELFIHDMPGLHRSLYLFERLLEDVEPAL 508

Query: 341 HVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIE-IVFKVALALLTLGK 399
           + H + +     LYA               L  R+ D+   EG+E  + K ALA++    
Sbjct: 509 YCHLRRRGVPPQLYATQWFLTLFAYRFPLQLVLRVYDLIFEEGLENTILKFALAIMRRNA 568

Query: 400 NDLLSL-DMESILKYIQKEL 418
           + LL + DM  +  ++++ L
Sbjct: 569 DTLLGMKDMAPLTTFLKERL 588


>UniRef50_Q4SF41 Cluster: Chromosome 1 SCAF14609, whole genome
           shotgun sequence; n=7; Euteleostomi|Rep: Chromosome 1
           SCAF14609, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 161

 Score =  138 bits (333), Expect = 8e-31
 Identities = 65/152 (42%), Positives = 93/152 (61%)

Query: 231 SACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLL 290
           SA E VI RDI RT+P HD+FK+ DG GQ+SL+ + KAYS++D E+GYC G  F+  +LL
Sbjct: 10  SAQEAVITRDIHRTFPAHDYFKDSDGDGQDSLYKICKAYSVYDDEIGYCPGQSFLAAVLL 69

Query: 291 MQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFS 350
           + MPEE+AF V+VKIM  + +R +++ +  +L    +QLE L+QE L DL  HFQ+ +  
Sbjct: 70  LHMPEEQAFCVMVKIMYDYGLRALYRNNFEDLHCKFYQLERLMQEQLSDLWSHFQALNLE 129

Query: 351 TSLYAXXXXXXXXXXXXXXPLACRIMDVFLSE 382
             +YA               +   I D+ L E
Sbjct: 130 AHMYASQWFLTLFTAKFPLCMVFHITDLLLCE 161


>UniRef50_Q9Y1V8 Cluster: HrPET-1; n=1; Halocynthia roretzi|Rep:
           HrPET-1 - Halocynthia roretzi (Sea squirt)
          Length = 532

 Score =  138 bits (333), Expect = 8e-31
 Identities = 75/237 (31%), Positives = 126/237 (53%), Gaps = 7/237 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAK 230
           W  ++++W+    +R   V++  R+G+P   RG  WQLL+G     E+    Y  Y+K +
Sbjct: 71  WLSMLNSWDKWMAKRFPQVKNRCRKGIPSSLRGRAWQLLSGSKALYEQNPGKYEEYLKMQ 130

Query: 231 --SACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
               C + I +D+ R +P H+ F +K G GQ+ L +V+ AYS+++RE GYCQ    I  +
Sbjct: 131 PDQNCVEDIEKDLHRQFPFHEMFVQKGGTGQQDLRDVLLAYSVYNREDGYCQAQAPIAAV 190

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LLM MP E+AF  +V  M +H ++  F P +  + +    ++ L++++    + H +   
Sbjct: 191 LLMHMPAEQAFWCIV-AMCEHYLQGYFSPGLEAIQVDGLVMQGLLRKVSGVAYKHLEKHQ 249

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLL 403
            S  LY               P   R+ D+F  EGI+++F+ AL +L  TLG +D L
Sbjct: 250 VSPVLYMTEWFMCVFSRTLSWPAVLRLWDMFFCEGIKVIFRCALVILRNTLGSSDKL 306


>UniRef50_A7S777 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 490

 Score =  138 bits (333), Expect = 8e-31
 Identities = 89/296 (30%), Positives = 148/296 (50%), Gaps = 11/296 (3%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLA---GVDTSPEKKLY---ASYIKAKS-AC--EKVIRRDI 241
           +RD V+ GVP   RG +W+ LA    V +   K  +    SY + +  +C  +  I  D+
Sbjct: 63  LRDAVKAGVPKDKRGEIWEFLAKQYSVRSPASKDAFWKAGSYEEMRDGSCNHQHSIFIDL 122

Query: 242 ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
            RT+P H +F  + G GQ SLFN++KAYS+ D +VGYCQG  F+ G+LLM M E +AF V
Sbjct: 123 GRTFPRHPYFTSQFGPGQLSLFNLLKAYSVLDTDVGYCQGLSFVAGILLMHMEEAKAFDV 182

Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
           +  ++    +R ++K  M EL +  + L  L+ +    L+   +    + +LYA      
Sbjct: 183 MRHLLFALDLRKLYKSDMTELQIQFYVLSRLLHDYHTPLYEFLEELDITPTLYAAAWFLT 242

Query: 362 XXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLD-MESILKYIQKELPL 420
                       R+MD+   +GI + FKV L LL+  K  ++  D  E  + YI+  +P 
Sbjct: 243 LFASQFPVGFVVRVMDMIFLQGITVCFKVMLLLLSRCKEGIMECDGFECAVDYIKTHVPP 302

Query: 421 KAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQ 476
            A A   + +     + +  K+++    EY V++ ++    +V     Q  + L+Q
Sbjct: 303 YAFAHMDSLVAQVLDMDI-CKELESYVIEYNVLREEDLSLASVEEFEHQRAKKLEQ 357


>UniRef50_Q92738 Cluster: USP6 N-terminal-like protein; n=34;
           Eumetazoa|Rep: USP6 N-terminal-like protein - Homo
           sapiens (Human)
          Length = 828

 Score =  136 bits (330), Expect = 2e-30
 Identities = 81/253 (32%), Positives = 129/253 (50%), Gaps = 9/253 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE--KKLYASYIKAK 230
           W +++  WE ++K   ++ R + + G+P   RG VW LL  +    E  + LY+      
Sbjct: 77  WLKMLKGWE-KYKNTEKFHRRIYK-GIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRA 134

Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
             C   IR+   D+ RT+ +H  F+++ G+ Q+SLF+V+ AYS+++ EVGYCQG   I  
Sbjct: 135 RGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITA 194

Query: 288 LLLMQMPEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           LLLM M EE+AF  LVK+    +H M   F     +L       E ++ + L  L  H  
Sbjct: 195 LLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD 254

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
           SQ   TS Y                L  RI D+++ EG  ++  ++  +L L K  L+ L
Sbjct: 255 SQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKL 314

Query: 406 DMESILKYIQKEL 418
            ME ++++ Q+ L
Sbjct: 315 SMEELVEFFQETL 327


>UniRef50_A6SIN1 Cluster: Putative uncharacterized protein; n=4;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 1023

 Score =  135 bits (327), Expect = 4e-30
 Identities = 87/316 (27%), Positives = 153/316 (48%), Gaps = 13/316 (4%)

Query: 109 LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETRPTPGTNGEE- 167
           LLA+LE+EN  I ++ K+  +  V   +                 ++   PTP       
Sbjct: 157 LLARLEQENNAIASNPKSG-IAKVQKVEKQRARAQSRPPSMQHLKKLVNGPTPSALRYSV 215

Query: 168 -------DLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK 220
                  DL   +  LV ++    +     +   +R G+P   RG+VWQ ++G      +
Sbjct: 216 TPPPPMTDL-EFYAALVQDYPRTAQYLPTLLSKKIRSGIPPPLRGVVWQSMSGARDRLLE 274

Query: 221 KLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQ 280
           + +       S  E +I +D+ R++P  + F++ +G GQ  L  V+K +SL+D ++GYCQ
Sbjct: 275 EQFDRLCGESSPYEGIIGKDLGRSFPGVEMFRDPEGDGQRMLGRVLKCFSLYDHKIGYCQ 334

Query: 281 GSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDL 340
           G GF+VG LLM M +++AF VLV++M+ + +R+ F P ++ L + + Q   L++  LP L
Sbjct: 335 GLGFLVGPLLMHMGDKQAFCVLVRLMEHYDLRNCFLPDLSGLHVRIHQFRELLKLHLPAL 394

Query: 341 HVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGI-EIVFKVALALLTLGK 399
             H        + Y               P+  RI DV  +EG  E + +VAL+L+   +
Sbjct: 395 STHLDVLQVEPA-YVSQWFLSFFATTCPLPMLFRIYDVIFAEGASETIMRVALSLMRKNE 453

Query: 400 NDLLS-LDMESILKYI 414
             +LS  + E +++ +
Sbjct: 454 TKILSCTEFEDVMQLL 469


>UniRef50_Q54YL8 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 933

 Score =  135 bits (326), Expect = 6e-30
 Identities = 93/291 (31%), Positives = 140/291 (48%), Gaps = 11/291 (3%)

Query: 164 NGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK-- 221
           N E+     W +L++N     K +N     L  + VP   R ++W+L+   D   E    
Sbjct: 612 NKEKRREKKWVKLIANHGKRSKMQN-----LAWKSVPESTRSVLWRLVLNPDKVKENANV 666

Query: 222 LYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQG 281
            +   ++  S   K I  DI RTY  H  F+E+   GQ++LFNV+KAYS++D EVGYCQG
Sbjct: 667 TFEQLLERDSEFVKQIDLDIDRTYRNHIIFRERFNSGQQALFNVLKAYSIYDSEVGYCQG 726

Query: 282 SGFIVGLLLMQMPEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPD 339
              I  LLLM M EEEAF  LV +M+  + + R +F PS   L       E L+ E LP 
Sbjct: 727 MSSIASLLLMYMTEEEAFWCLVALMENDKFQFRGLFLPSFPLLYRNYAIHEQLLHEELPK 786

Query: 340 LHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGK 399
           +  +F  +  + S+YA              PL  R  D+ +  G  IV  + + +L   +
Sbjct: 787 VASNFGVEGITFSMYATKWFLTIFSGNIPFPLLVRFWDLVMLHGYFIVHTLVIHILRTYE 846

Query: 400 NDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           + L     E IL +      +  E D  +F+  A   K+  K++ KL ++Y
Sbjct: 847 STLGKDPFEKILNFFSNLDSI--EIDVYSFIKSAKKYKITEKRIAKLGQKY 895


>UniRef50_Q4DHN9 Cluster: Rab6 GTPase activating protein, putative;
           n=1; Trypanosoma cruzi|Rep: Rab6 GTPase activating
           protein, putative - Trypanosoma cruzi
          Length = 385

 Score =  134 bits (325), Expect = 8e-30
 Identities = 78/236 (33%), Positives = 123/236 (52%), Gaps = 11/236 (4%)

Query: 192 RDLVRQGVPHH-FRGIVWQLLAGVDTSPEKKL---YASYIKAKSA-----CEKVIRRDIA 242
           R L+  GV H   R ++W    G    PE  +   +A+Y+  KS+       + I+RD++
Sbjct: 103 RILLFGGVRHETLRRLLWGFFTGSLQRPESVVRAHHATYVSLKSSPPDKKTVEAIQRDLS 162

Query: 243 RTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVL 302
           RT+P H  F  +  +GQ  L  ++  YS  D  VGYCQG  F+V +LL+  PEEEAF +L
Sbjct: 163 RTFPTHCLFVGEGSVGQVELRRILSVYSRLDPAVGYCQGMAFVVAMLLLHAPEEEAFGML 222

Query: 303 VKIMQQ--HRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           + +       MR+MF P    L + +  L  L++ LLP L+ HF     +   +A     
Sbjct: 223 LHLFYSPPFLMREMFLPGFTRLRVFLAVLRRLIERLLPALNRHFLDIGLNVFFFAPQWFL 282

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQK 416
                       CR+ D+FL +G  ++F+ A+A+L   +  LLSLDME+ L ++++
Sbjct: 283 TLYTYHFPLDFVCRLWDIFLVDGWRVLFQAAIAILQGEQEQLLSLDMEATLLWLKE 338


>UniRef50_Q6FSG3 Cluster: Candida glabrata strain CBS138 chromosome
           H complete sequence; n=1; Candida glabrata|Rep: Candida
           glabrata strain CBS138 chromosome H complete sequence -
           Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 1042

 Score =  134 bits (323), Expect = 1e-29
 Identities = 71/250 (28%), Positives = 129/250 (51%), Gaps = 8/250 (3%)

Query: 170 WSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA 229
           W+ W  +V+++ +   +  + +   V  G+P   RGI+WQL+    +   + +Y + +  
Sbjct: 563 WTFWTEVVNDFPAVASQEPEKLEQQVIAGIPTQIRGIIWQLMTNSKSKEMEDIYNTLLPE 622

Query: 230 KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
            +  +  IRRD+ RT    +F  ++     E L+NV+K Y++ D EVGY QG  F++  L
Sbjct: 623 PTPHDAAIRRDLKRT----NFIPQEK---IEPLYNVIKVYTIFDPEVGYTQGMAFVIAPL 675

Query: 290 LMQMPEE-EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           L+    E +AF +LV +M+ + +RD + P M  L L ++Q + +++E    L  H   + 
Sbjct: 676 LLNCETEADAFGLLVGLMKNYGLRDFYLPEMPGLVLSLYQFDRIIEENSSQLSNHLNREG 735

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
              S+YA                  RI+DV   EG+E + K A+ L+   +  +LSL  +
Sbjct: 736 VRASMYATQWFLTMFAYKFPLSFVLRILDVIFVEGLESILKFAVNLMLKNEAKILSLKFD 795

Query: 409 SILKYIQKEL 418
            +L ++++EL
Sbjct: 796 QLLSFLKEEL 805


>UniRef50_Q5ZMK6 Cluster: Putative uncharacterized protein; n=12;
           Amniota|Rep: Putative uncharacterized protein - Gallus
           gallus (Chicken)
          Length = 481

 Score =  130 bits (313), Expect = 2e-28
 Identities = 77/279 (27%), Positives = 140/279 (50%), Gaps = 9/279 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP---EKKLYASYIKA 229
           W +++  W  +++  ++  R  V +G+P   RG VW LL  V+      E K      +A
Sbjct: 76  WLKMLKKW-GKYRNSDKMCRR-VYKGIPLQVRGQVWSLLLDVEKMKKENEGKYEQMKQQA 133

Query: 230 KSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
           KS   ++  I  D+ RT+  H  F+++ G+ Q++LF+V+ AYS+++ EV YCQG   I  
Sbjct: 134 KSWSSEIKQIDLDVNRTFRNHIMFRDRYGVKQQALFHVLSAYSVYNTEVSYCQGMSQIAA 193

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           +LLM + EE+AF  L +++  Q+H M   F P   +L       E ++ +L P L  H  
Sbjct: 194 ILLMYLNEEDAFWALAQLLTNQKHAMHGFFIPGFPKLQRFQAHHEQILSKLFPKLKKHMD 253

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            +  +T +Y                L  R+ D+++ EG  ++  +A  +L L K  LL +
Sbjct: 254 KEQMTTGIYTTKWFLQCFIDRTPFTLTLRLWDIYILEGERVLTAMAYTILKLHKKRLLKM 313

Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMK 444
            +E + +++Q+++    + +  A ++         +KMK
Sbjct: 314 TLEDLREFLQEKIAASLQYEDDAVIDQLQVSMSELRKMK 352


>UniRef50_Q54SQ5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 787

 Score =  130 bits (313), Expect = 2e-28
 Identities = 83/283 (29%), Positives = 137/283 (48%), Gaps = 7/283 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLL--AGVDTSPEKKLYASYIKAK 230
           W  ++  +    K   ++    ++ G+P   R  VW LL  A  + S    L+   +   
Sbjct: 499 WNAMIKRYNLNHKFTGKFKSRSIK-GIPDRMRSEVWPLLSHAQEEKSRNPGLFNQLVNQH 557

Query: 231 SACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLL 290
           SA E  I  D+ R Y  H FF+E+ G+GQ SLFNV+K YSL+D+ VGY QG   I  LL+
Sbjct: 558 SANEIYIDLDVNRAYRNHIFFRERYGMGQVSLFNVLKVYSLYDQGVGYTQGMSSIASLLV 617

Query: 291 MQMPEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           M + EE+AF  L  +M   ++ MR MF   +  L    F  ENL+    P       + +
Sbjct: 618 MYLSEEDAFWTLQSLMSRPEYSMRSMFLSGLPGLIRMSFVFENLLNHYFPAAKNALDNIN 677

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
            +T+LY+               ++ R+ D+  SEG  IV+ +A+AL  L +  +L+ + +
Sbjct: 678 LTTTLYSTKWFLIGFLDSFPFHISLRVWDLIFSEGYTIVYSIAMALFRLNEKSILA-NKD 736

Query: 409 SILKYIQKELPLKA-EADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           S  K        +  E D+  F+      +++ K+++  E ++
Sbjct: 737 SFEKCYNILRSFETFEIDEDIFIKYVIKHRISSKRIQYWEDKH 779


>UniRef50_Q8IV04 Cluster: Carabin; n=12; Eutheria|Rep: Carabin -
           Homo sapiens (Human)
          Length = 446

 Score =  130 bits (313), Expect = 2e-28
 Identities = 85/281 (30%), Positives = 134/281 (47%), Gaps = 11/281 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAK 230
           W  + S+WE    RR + V+   R+G+P   R   W LL G     +     Y    +A 
Sbjct: 67  WVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAEAP 126

Query: 231 SACE--KVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
              +  + I RD+ R +P H+ F    G GQ+ L  V+KAY+L+  E GYCQ  G +  +
Sbjct: 127 GDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAV 186

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LLM +P EEAF  LV+I + + +   + P M  + L       L++ LLP +H H Q   
Sbjct: 187 LLMHLPPEEAFWCLVQICEVY-LPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVG 245

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL--LTLGKNDLLSLD 406
               LY               P   R+ D FLSEG  ++F+V L L  L LG  +     
Sbjct: 246 VGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAEQRGA- 304

Query: 407 MESILKYI--QKELPLKAEADQAAFMNLAYSVKVNPKKMKK 445
              +L+ +   + +P  A+  + AFM+  +SV ++ + +++
Sbjct: 305 CPGLLETLGALRAIP-PAQLQEEAFMSQVHSVVLSERDLQR 344


>UniRef50_Q245C4 Cluster: TBC domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: TBC domain containing
           protein - Tetrahymena thermophila SB210
          Length = 454

 Score =  129 bits (311), Expect = 4e-28
 Identities = 71/236 (30%), Positives = 127/236 (53%), Gaps = 5/236 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASY---IK- 228
           W +++ N E   + +N+ ++  +R+G+P   R  VW  L  ++   +K +   Y   IK 
Sbjct: 48  WRKMLPNIEQLIQSKNEKLKTRIRKGIPDGIRLKVWPHLGQIEALKKKYINQGYNYLIKQ 107

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
           A    E  I  D+ RT+P H  F+++   G ESL NV+KA SL   ++GYCQG  FI   
Sbjct: 108 ADFPYETDIDADLNRTFPNHQLFRDQKNTGIESLKNVLKAVSLTHEDMGYCQGLNFIAAA 167

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
            ++ + +EE++ +++ +++ +  + M++  +A +   +F  ++LV++ LPD+  HFQ+  
Sbjct: 168 FMIYINDEESYYMIISLLENYDCKKMYE-DVASIRKQLFVHDHLVKKFLPDISEHFQNYG 226

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
             +  +                   RIMD+F  E  +IV++VALA+L L K  LL+
Sbjct: 227 IESITFGTSWYMTLFSSVLPFQYFLRIMDIFFFEKWKIVYRVALAMLKLKKKRLLN 282


>UniRef50_Q7RUP0 Cluster: Putative uncharacterized protein
           B11B22.30; n=6; Pezizomycotina|Rep: Putative
           uncharacterized protein B11B22.30 - Neurospora crassa
          Length = 951

 Score =  128 bits (310), Expect = 5e-28
 Identities = 73/190 (38%), Positives = 102/190 (53%), Gaps = 5/190 (2%)

Query: 231 SACEKVIRRDI-ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
           S  EKVIRRD+ ART   +  F    GL QE LF V KAY+L D  VGY QG  F+V  L
Sbjct: 531 SRLEKVIRRDLGART--SYSKFAAAQGL-QEGLFGVCKAYALFDEAVGYAQGMNFLVMPL 587

Query: 290 LMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSF 349
           L  MPEEEAF +LV++M Q+ +R++F   M  L  C++Q E ++++L P L+ H   +  
Sbjct: 588 LFNMPEEEAFCLLVRLMNQYHLRELFIQDMPGLHKCLYQFERILEDLEPALYCHLHRRGI 647

Query: 350 STSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DME 408
           S  LYA               L  RI D+  SEG+  + K  + L+      LL + DM 
Sbjct: 648 SPHLYATQWFLTLFAYRFPLQLVLRIYDLIFSEGLSAIIKFGIVLMQKNATALLGMSDMS 707

Query: 409 SILKYIQKEL 418
            +  +++  L
Sbjct: 708 QLTTFLKDRL 717


>UniRef50_Q9BXI6 Cluster: TBC1 domain family member 10A; n=32;
           Coelomata|Rep: TBC1 domain family member 10A - Homo
           sapiens (Human)
          Length = 508

 Score =  128 bits (308), Expect = 9e-28
 Identities = 86/302 (28%), Positives = 144/302 (47%), Gaps = 10/302 (3%)

Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASY 226
           S W  +++NW+    ++++ +R   ++G+P   RG  WQ L+G    +  +P K      
Sbjct: 84  SKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDM 143

Query: 227 IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
                    VI RD+ R +P H+ F  + G GQ+ LF V+KAY+L+  E GYCQ    I 
Sbjct: 144 SPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIA 203

Query: 287 GLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
            +LLM MP E+AF  LV+I +++ +   +   +  + L    L +L+Q++ P  H H   
Sbjct: 204 AVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR 262

Query: 347 QSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLLS 404
           Q     LY                   R+ D+F  EG++I+F+V L LL   LG  + + 
Sbjct: 263 QKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVK 322

Query: 405 LDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVL 464
              +   + I++   L  +  Q AF  L   V   P   +++E+E+ +   + Q     L
Sbjct: 323 A-CQGQYETIERLRSLSPKIMQEAF--LVQEVVELPVTERQIEREHLIQLRRWQETRGEL 379

Query: 465 RC 466
           +C
Sbjct: 380 QC 381


>UniRef50_UPI000054717C Cluster: PREDICTED: similar to TBC1 domain
           family, member 10C; n=2; Danio rerio|Rep: PREDICTED:
           similar to TBC1 domain family, member 10C - Danio rerio
          Length = 1383

 Score =  126 bits (303), Expect = 4e-27
 Identities = 82/288 (28%), Positives = 141/288 (48%), Gaps = 10/288 (3%)

Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIK 228
           S W  L++ WE   ++++  V+   ++G+P   R   W LL G     EK   LY S ++
Sbjct: 51  SKWLGLMTQWEQVMEKKSHKVKSQCQKGIPASVRIKCWPLLCGAKDRKEKNSTLYNSLVE 110

Query: 229 AKS--ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
           A       ++I+RD  R +P H+ F  KDG GQ+ L  V+KAY+ +  + GYCQ  G + 
Sbjct: 111 APDHQGWIEIIKRDTDRQFPFHEMFLSKDGHGQKDLLEVLKAYTQYRPDEGYCQAQGPVA 170

Query: 287 GLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
            +LLM MP EEAF  LV+I + + +   + P +  +      L +++++L P  H H Q 
Sbjct: 171 AVLLMNMPAEEAFWCLVQISELY-LPGYYSPLLEGVLFDAAVLSSVLKKLCPAAHKHLQG 229

Query: 347 QSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKND-LLSL 405
           Q     ++A                  R+ D+F   G+ ++F+VA+ L+     D  L  
Sbjct: 230 QGVEPLMFATDWLMCLFSRHLPFNTLLRVWDLFFCYGVRVLFQVAVVLVRRCLGDGRLRK 289

Query: 406 DMESILKYIQKELPLKAEADQA---AFMNLAYSVKVNPKKM-KKLEKE 449
           + +  ++ +++   +K         AF+N   SV ++   + K+ EKE
Sbjct: 290 ECDGQMETLERLRSVKQRVQNEQTDAFINEVCSVSLSLADLQKQTEKE 337


>UniRef50_Q4Q0F2 Cluster: Rab-like GTPase activating protein,
           putative; n=3; Leishmania|Rep: Rab-like GTPase
           activating protein, putative - Leishmania major
          Length = 414

 Score =  124 bits (298), Expect = 1e-26
 Identities = 85/288 (29%), Positives = 145/288 (50%), Gaps = 16/288 (5%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA---GV-DTSPE--KKLYASY 226
           W  ++++W +    R   ++   R+GVP   R  VWQ L    G+ D  P    +L++  
Sbjct: 128 WEYMMTHWANV---RQDTLKRYCRRGVPQPKRCAVWQHLLQSWGMKDRFPGVYMRLHSQP 184

Query: 227 IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
           + +K   + VI RD+ RT+P +  F  K G GQ+ L  ++ AY+ ++  VGYCQG GF+ 
Sbjct: 185 LDSKDLAD-VIARDLDRTFPTNRLFSVKSGQGQQILRRLLHAYANYNPGVGYCQGMGFLA 243

Query: 287 GLLLMQMPEEE-AFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
             L++Q+ EEE AF   V +M+  ++ M+ +F PS  +L    +  E L+++ +P L+ H
Sbjct: 244 ATLILQVEEEEDAFWAFVAVMENAKYNMKAVFAPSFPQLQCAFYVFEALMRQKMPKLYAH 303

Query: 344 FQSQ-SFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
              +     S YA               L  RI D+F  EG + V+++ALALL + +  L
Sbjct: 304 LHDRHPIPPSFYAVHWFMTIFTYHFNFGLVSRIWDMFFCEGWKPVYRIALALLKIEERRL 363

Query: 403 LSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           LSL+ ++ L  + K   ++        +  A  ++     M +L  E+
Sbjct: 364 LSLNTDTELLLVLK--GIQESKRPVELLKTALKIRFKSAYMNQLMAEF 409


>UniRef50_Q553Q2 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 702

 Score =  122 bits (294), Expect = 4e-26
 Identities = 79/256 (30%), Positives = 133/256 (51%), Gaps = 10/256 (3%)

Query: 178 SNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKA----KS 231
           S+++S  ++  + +++L+R G+P  +R ++W   +G     S  +  Y + +K     KS
Sbjct: 402 SSYKSYRQKIPKPLKELIRGGIPGEYRSMLWFRASGGYARLSENQDEYFNILKENAGKKS 461

Query: 232 ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM 291
              K I  D+ RT+P+H F   K+ +  ESL NV+ AYS  + +VGYCQ   FI G LL+
Sbjct: 462 VAVKQILMDVDRTFPDHKFLNTKEKM--ESLTNVLVAYSWRNPKVGYCQCMNFIAGYLLI 519

Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGL-CMFQLENLVQELLPDLHVHFQSQSFS 350
            M E EA+  LV I+++    + F  +M +  +   F  ++L+Q+ +P LH H  S + +
Sbjct: 520 YMSEPEAYWTLVSIIEELLPTEYFTNTMIDSSVDVRFVFDDLLQKKIPRLHQHLTSFNLT 579

Query: 351 TSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMES 409
             L                    RI DVF SEG +++F+VAL+   L +  +LS  D  +
Sbjct: 580 LPLIITQWFLCIMATTTPTETTFRIWDVFFSEGSKVLFRVALSFFKLSEEKILSCRDYGT 639

Query: 410 ILKYIQKELPLKAEAD 425
           +   I+K   +  +AD
Sbjct: 640 LYNLIKKVPSVMYDAD 655


>UniRef50_Q54WP7 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1229

 Score =  122 bits (294), Expect = 4e-26
 Identities = 73/234 (31%), Positives = 116/234 (49%), Gaps = 6/234 (2%)

Query: 218  PEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVG 277
            P K  Y S IK     ++ I  D+ R++PE +    +   GQ  L NV+KA SL D E+G
Sbjct: 849  PHKCFYRSIIKFPCKDDEQIEVDLIRSFPETESELVEIYTGQ--LRNVLKAISLFDPEIG 906

Query: 278  YCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELL 337
            YCQG  F+  L++  + EEEAF +LV++     MRD +   M  L L +FQL+  V+ L 
Sbjct: 907  YCQGMSFVAALIIPYLSEEEAFHILVRLFNGV-MRDFYGVGMKALQLRVFQLKKFVELLF 965

Query: 338  PDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTL 397
            P LH H        S++                +A RI+DV   +G+E  F VALA+  +
Sbjct: 966  PKLHAHLNEIELDISIFTSPWFLTVFAYHFSDEVATRILDVIFLQGLEAFFSVALAIFQI 1025

Query: 398  GKNDLLSLDMES-ILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
             + DL+     S  + Y +     K + D    M  A+ ++V+  ++   ++++
Sbjct: 1026 IEADLMECSENSQAMAYFRNNTKTKIDVD--TLMTTAFKIRVSQTQLANFKQQF 1077


>UniRef50_UPI000065EE1A Cluster: TBC1 domain family, member 3C
           (TBC1D3C), mRNA; n=1; Takifugu rubripes|Rep: TBC1 domain
           family, member 3C (TBC1D3C), mRNA - Takifugu rubripes
          Length = 723

 Score =  122 bits (293), Expect = 6e-26
 Identities = 80/280 (28%), Positives = 134/280 (47%), Gaps = 18/280 (6%)

Query: 153 HEVETRPTPGTNGE----EDLWSL--WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGI 206
           HE E  PTP    E    +DL  +  W ++V NW+    R ++ +   V +G+P   RG 
Sbjct: 54  HEEEL-PTPSALEEKQKQQDLKRVEKWLKMVKNWDKY--RNSEKLVKRVYKGIPLQLRGQ 110

Query: 207 VWQLLAGVDTSPEKKLYASYIKAKSACE------KVIRRDIARTYPEHDFFKEKDGLGQE 260
            W LL  ++   +      Y K K          K I  D+ RT+  H  F+E+ G+ Q+
Sbjct: 111 AWALLLDIEKVKQDN-EGKYEKMKQQARTFSTEIKQIDLDVNRTFRNHIMFRERFGVKQQ 169

Query: 261 SLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPS 318
           +LF+V+ AYS+++ EV YCQG   I  +LLM + EE+AF  L +++   +H M   F P 
Sbjct: 170 ALFHVLAAYSVYNTEVSYCQGMSQIAAILLMYLNEEDAFWALSQLLTNSKHAMHGFFIPG 229

Query: 319 MAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDV 378
             +L       E ++ ++LP L  H   +  +T +Y                L  R+ D+
Sbjct: 230 FPKLHRFQAHHELILSKMLPKLKKHLDKEQMTTGIYTTKWFLQCFIDRTPFTLTLRLWDI 289

Query: 379 FLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKEL 418
           ++ +G + +  +A     L K  L  L +E + +++Q+ L
Sbjct: 290 YILDGEKTLTAMAYTTFKLHKKHLQKLQLEDLREFLQERL 329


>UniRef50_Q019L3 Cluster: Predicted GTPase activator NB4S/EVI5
           (Contains TBC domain)/Calmodulin- binding protein
           Pollux; n=2; Ostreococcus|Rep: Predicted GTPase
           activator NB4S/EVI5 (Contains TBC domain)/Calmodulin-
           binding protein Pollux - Ostreococcus tauri
          Length = 430

 Score =  122 bits (293), Expect = 6e-26
 Identities = 66/186 (35%), Positives = 102/186 (54%), Gaps = 5/186 (2%)

Query: 237 IRRDIARTYPEHDFF---KEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQM 293
           I RD+ RT+P H+FF     K   G+ +L N++KAY++HD +VGYCQG  F+ GLLL+ +
Sbjct: 172 IERDLKRTFPHHEFFVASTAKGDAGRAALANILKAYAMHDSKVGYCQGMAFVAGLLLIYL 231

Query: 294 PEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSL 353
           PE  AFA  V +M+    R M+  SM  L + + QL  +V+   P L  H ++   +  L
Sbjct: 232 PENRAFAAFVTLMEGSDFRSMYVHSMEGLKVRLRQLGAVVRAKNPTLAHHLEAHDVTPVL 291

Query: 354 YAXXXXXXXXXXXXXXPLACRIMDVFLSE-GIEIVFKVALALLTLGKNDLLSL-DMESIL 411
           YA                + R+MD  L++    ++ ++ LA+L     DLL L D E+I+
Sbjct: 292 YASGWFMSAFASDFPVRFSGRVMDCLLAQRSPSLIMRICLAILNEAAGDLLKLGDFEAIV 351

Query: 412 KYIQKE 417
            Y++ E
Sbjct: 352 VYLRTE 357


>UniRef50_Q16XR6 Cluster: Ecotropic viral integration site; n=4;
           Endopterygota|Rep: Ecotropic viral integration site -
           Aedes aegypti (Yellowfever mosquito)
          Length = 526

 Score =  121 bits (292), Expect = 8e-26
 Identities = 76/236 (32%), Positives = 121/236 (51%), Gaps = 10/236 (4%)

Query: 195 VRQGVPHHFRGIVWQLLAGV-----DTSPEKKLYASYIKAK--SACEKVIRRDIARTYPE 247
           V +G+P   R  VW  L  +     D     K       A+  S   + I  D+ R + E
Sbjct: 100 VYKGIPDSLRHTVWSRLLNLGKVMEDAKNRNKYQEMLTLARTWSTEARQIDSDVNRQFRE 159

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM- 306
           H F++E+  + Q+SLFNV+ AYS+++ EVGYCQG   + GLLLM M EEEAF  L  ++ 
Sbjct: 160 HVFYRERYSVKQKSLFNVLVAYSMYNTEVGYCQGMSGLAGLLLMYMDEEEAFWALSILLS 219

Query: 307 -QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXX 365
            +++ M  +F     +L   +   + ++ + +P L  HF   +  + LY+          
Sbjct: 220 DRKYAMHGLFIEGFPKLTRFLAHHDKIIAKFIPKLKKHFDQYNLDSILYSLKWFFVVFIE 279

Query: 366 XXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQKELPL 420
                L  R+ DV+L +G ++V  +A  +L L K  +L L DM+ I++YIQ +L L
Sbjct: 280 RIPFSLCLRVWDVYLLDGEKVVTAMAYTILRLHKTKILKLKDMDLIVQYIQTKLHL 335


>UniRef50_UPI0000ECBE92 Cluster: EVI5-like protein (Ecotropic viral
           integration site 5-like protein).; n=2; Gallus
           gallus|Rep: EVI5-like protein (Ecotropic viral
           integration site 5-like protein). - Gallus gallus
          Length = 292

 Score =  120 bits (290), Expect = 1e-25
 Identities = 58/125 (46%), Positives = 82/125 (65%)

Query: 333 VQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL 392
           VQE LP+L++HF+SQSF TS+YA              P+A R+ D+F+ EG+EIVF+V +
Sbjct: 160 VQEQLPELNIHFRSQSFLTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGM 219

Query: 393 ALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTV 452
           ALL   + +L+ LDME + +Y QK +P + ++     +  A+ VK NPKKMK+LEKEY  
Sbjct: 220 ALLQFNQAELVQLDMEGMSQYFQKVIPHQFDSCPDKLILRAFQVKYNPKKMKRLEKEYKG 279

Query: 453 IKTKE 457
           IK KE
Sbjct: 280 IKNKE 284



 Score = 37.5 bits (83), Expect = 1.6
 Identities = 12/24 (50%), Positives = 19/24 (79%), Gaps = 1/24 (4%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQ 189
           EED W LWGR+V+ W+ EW+++ +
Sbjct: 38  EEDTWILWGRIVNEWD-EWRKKKE 60


>UniRef50_Q9VGL8 Cluster: CG5344-PA, isoform A; n=5;
           Endopterygota|Rep: CG5344-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 363

 Score =  120 bits (290), Expect = 1e-25
 Identities = 67/227 (29%), Positives = 112/227 (49%), Gaps = 5/227 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAK 230
           W  ++ NW     +  + +RD  R+G+P   R   W  L+G     +K   +Y   ++  
Sbjct: 52  WLYMIDNWSIYMSKNYKKIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKP 111

Query: 231 SACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
                +  I++D  R +P H+ F ++  +GQ  LFNV+KAYS+++ +VG+CQ    I   
Sbjct: 112 GNPTTIEEIKKDKHRQFPFHEMFLDEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIAAF 171

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LLM +P E+AF V V +   + ++D F P +  +      LE L+++  P ++ H Q   
Sbjct: 172 LLMHLPAEDAFWVFVSVCDVY-LQDYFIPGLEVIQNDAGILEGLLKKTCPPVYRHLQKHK 230

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
               LY                   R+ D FL+EGI ++FKVAL ++
Sbjct: 231 VEPLLYMTDWFLCAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVII 277


>UniRef50_Q0UL58 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Phaeosphaeria nodorum (Septoria nodorum)
          Length = 867

 Score =  120 bits (288), Expect = 2e-25
 Identities = 70/191 (36%), Positives = 106/191 (55%), Gaps = 6/191 (3%)

Query: 231 SACEKVIRRDI-ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
           S  EK I+RD+ ART   +  +    GL Q+ LF + KAY+L+D  VGY QG  FI   L
Sbjct: 474 SKLEKTIKRDLGART--SYSKYVMAAGL-QDGLFGICKAYALYDEAVGYAQGMNFIAMPL 530

Query: 290 LMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSF 349
           L  MPEEEAF++ V +M ++ +RD+F   MA L L ++Q E L++E  P L+ H + +  
Sbjct: 531 LFNMPEEEAFSLFVTLMNKYGLRDLFVADMAGLHLHLYQFERLLEEFEPALYCHLRRREV 590

Query: 350 STSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEI-VFKVALALLTLGKNDLLSL-DM 407
              LYA               L  RI D+ LSEG+E+ + K  + L+      LL + DM
Sbjct: 591 KPQLYATQWFLTLFAYRFPLQLVLRIYDLILSEGLELAILKFGIVLMQKNAEALLGMKDM 650

Query: 408 ESILKYIQKEL 418
            ++  +++++L
Sbjct: 651 STLTTFLKEKL 661



 Score = 38.3 bits (85), Expect = 0.91
 Identities = 55/242 (22%), Positives = 112/242 (46%), Gaps = 22/242 (9%)

Query: 621 IAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP--VQSNVVSDIMATPKK 678
           I +  + AEA L +KD+    + L E   +    +  +AP+A   +++          K+
Sbjct: 634 IVLMQKNAEALLGMKDMSTLTTFLKE---KLFDVYIDKAPSANSILENGFFGSTAGIDKE 690

Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDE 737
           + RA      DML  D   +      ++  T E KE R    + ET++    +++   + 
Sbjct: 691 VYRA------DMLVKDAVAIKISPEMLKQYTAEWKEQRRIDKDRETELHGLKDRVASLET 744

Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELET 797
           + RLL EN       E  +Q      + K  + +   + E+++  +   E+ Q+I + + 
Sbjct: 745 KVRLL-ENRAEQSDMEH-VQVASELIKTKVENEQIAEENETLKTKV---EELQKIVDTQA 799

Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSRALGHTEL 856
           E  E +LK+E+   E  ++ N +  ++  R L+EQ+AE++ E++  +  W +    H +L
Sbjct: 800 EEVEARLKSEM---ETVMQKNIVVHNEN-RALEEQMAEMEKELVAAKMEWATINEEHEKL 855

Query: 857 SR 858
           ++
Sbjct: 856 TQ 857



 Score = 36.3 bits (80), Expect = 3.7
 Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 1/93 (1%)

Query: 170 WSLWGRLVSNWESEWKRRN-QWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIK 228
           W LW  +V+   +   R + + +   +  G+P   RG++WQ+LA   +   + +Y   + 
Sbjct: 329 WDLWQSVVNEGPTAIARTSSEELSRAIANGIPQVIRGVIWQVLAQSKSEELEGMYRELVA 388

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQES 261
             +  E +  +    + P +   +EKD +   S
Sbjct: 389 RGTDKEHMTVKTPNTSAPTNGNGREKDSVASSS 421


>UniRef50_Q4SDZ5 Cluster: Chromosome 13 SCAF14627, whole genome
           shotgun sequence; n=7; Clupeocephala|Rep: Chromosome 13
           SCAF14627, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 691

 Score =  119 bits (287), Expect = 3e-25
 Identities = 70/253 (27%), Positives = 127/253 (50%), Gaps = 9/253 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK---KLYASYIKA 229
           W ++V NW+    R ++ +   V +G+P   RG  W LL  ++   +    K     ++A
Sbjct: 80  WLKMVKNWDKY--RNSEKLVKRVYKGIPLQLRGQAWALLLDIEKVKQDNKGKYEKMKLQA 137

Query: 230 KSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
           ++   ++  I  D+ RT+  H  F+E+ G+ Q++LF+V+ AYS+++ EV YCQG   I  
Sbjct: 138 RTFSTEIKQIDLDVNRTFRNHIMFRERFGVKQQALFHVLAAYSVYNTEVSYCQGMSQIAA 197

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           +LLM + EE+AF  L +++   +H M   F P   +L       E ++ ++LP L  H  
Sbjct: 198 ILLMYLNEEDAFWALSQLLTNSKHAMHGFFIPGFPKLQRFQAHHELILSKMLPKLKKHLD 257

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            +  +T +Y                L  R+ DV++ +G + +  +A     L K  L  L
Sbjct: 258 KEQMTTGIYTTKWFLQCFIDRTPFTLTLRLWDVYILDGEKTLTAMAYTTFKLHKKHLQKL 317

Query: 406 DMESILKYIQKEL 418
            +E + +++Q+ L
Sbjct: 318 LLEDLREFLQERL 330


>UniRef50_UPI00015B5223 Cluster: PREDICTED: similar to ecotropic
           viral integration site; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ecotropic viral integration site -
           Nasonia vitripennis
          Length = 594

 Score =  117 bits (282), Expect = 1e-24
 Identities = 77/286 (26%), Positives = 138/286 (48%), Gaps = 13/286 (4%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDT--SPEKKLYASYIKAK 230
           W ++   WES   +    +R  + +G+P  FRG VW LL G+    S +   Y   +   
Sbjct: 78  WEKMTKQWESPATKEK--LRRRIYKGIPDRFRGQVWVLLLGITKLKSEQAGKYEEMLALA 135

Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
                 IR+   D+AR Y +H  ++E+  L Q S+F V+ AYS+++ EVGYCQG   + G
Sbjct: 136 RQWSTEIRQIDADVARQYRDHINYRERYSLKQRSMFYVLAAYSMYNMEVGYCQGMSVLAG 195

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           LLL+ M EEEAF  L  ++  +++ M   +     +L   +   + ++ + LP L     
Sbjct: 196 LLLLYMDEEEAFWGLSVLLTDKKYSMHGFYVDGFPKLNRYIEHHDKIMGKFLPKLKRKLD 255

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
                + LYA               L  RI D+FL +G  ++  +A  ++ + K  L+++
Sbjct: 256 KCGCDSILYALKWFFVVFQERTPVSLGLRIWDIFLLDGDRVLPAIAYTVMKMHKRQLMTM 315

Query: 406 D-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           + ++    Y+Q +L      D    +N   +V+ +  ++K+ + +Y
Sbjct: 316 ESLDEFCNYLQIKLEKDFGYDDDTVIN---TVERSMDELKRAKLDY 358


>UniRef50_Q10496 Cluster: Uncharacterized protein C26F1.09; n=1;
           Schizosaccharomyces pombe|Rep: Uncharacterized protein
           C26F1.09 - Schizosaccharomyces pombe (Fission yeast)
          Length = 1031

 Score =  117 bits (281), Expect = 2e-24
 Identities = 75/303 (24%), Positives = 145/303 (47%), Gaps = 18/303 (5%)

Query: 192 RDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKVIRRDIARTY-PE--H 248
           R+L+     H    +VW+ ++   +   +  Y+S        +K IR+D+ RT+ PE   
Sbjct: 604 RNLILMHNSHTVHTVVWKTISSWTSYDYEMQYSSLSIKNCDSDKAIRKDLDRTFAPEILS 663

Query: 249 DFFKEK------DGLGQES--LFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
            FF  +      D + + +  L  V+++ ++   +VGY QG  +I G LLM +P  +AFA
Sbjct: 664 HFFSNRQQLEPTDNIAESTANLHRVLRSLAIVLPQVGYTQGMSWIAGALLMHLPAPQAFA 723

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           +LV + + + ++++F   M  L   + Q   LV++ +P L +HF+ Q   T  YA     
Sbjct: 724 LLVFLFKNYHLQNIFSSEMRGLSRVLHQFTRLVEDYMPSLAIHFKRQDIKTCSYASEWFL 783

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
                     +   + D+    G  I+F   LALL+  +  LL L+M+ ++ Y+++++ L
Sbjct: 784 TLFAYKFPLEVVAHLYDILFLYGPGILFNFGLALLSHSQESLLKLNMDRLISYLKEDIFL 843

Query: 421 KAEA-------DQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRL 473
             +        D + F+  A+S ++ P  + +   EY ++   E    + L  +R  ++ 
Sbjct: 844 AFKETQEGENYDTSLFVKTAFSFEIQPDVLDRYGNEYDILLKSEHELDSSLEEMRNRHKS 903

Query: 474 LKQ 476
           L +
Sbjct: 904 LNE 906


>UniRef50_A1Z9K4 Cluster: CG8085-PA, isoform A; n=6; Sophophora|Rep:
           CG8085-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 571

 Score =  116 bits (280), Expect = 2e-24
 Identities = 69/245 (28%), Positives = 126/245 (51%), Gaps = 8/245 (3%)

Query: 182 SEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK----LYASYIKAKSACE-KV 236
           ++W      +   V +G+P   R + W  L  +  S        L    +  K + E + 
Sbjct: 87  NQWPPPQDKLHKRVYKGIPDRVRMVAWNKLLDIQQSINNNAGVYLRMLQLARKYSTETRQ 146

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
           I  D+ R + ++  F+E+  + Q SLFNV+ AYS+++ E+GYCQG   + G+LL+ + EE
Sbjct: 147 IDADVNRQFRDNLAFRERYSVKQCSLFNVLNAYSIYNSELGYCQGMACVAGVLLLYLHEE 206

Query: 297 EAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLY 354
           EAF  L  ++  Q++ M  +F     +L   +   + ++ +++  LH HF   +    LY
Sbjct: 207 EAFWALNTLITDQKYGMHGLFIEGFPKLTRFIDHHDRIMSKIMRKLHKHFTKHNVDALLY 266

Query: 355 AXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKY 413
           A               L+ R+ D+F+ +G  ++  +A+ +L L K++LL L DM++I++Y
Sbjct: 267 AIKWFFVVFVERVPFSLSLRVWDIFMLDGDRVILSMAITILYLHKDELLRLKDMDAIIEY 326

Query: 414 IQKEL 418
           +Q  L
Sbjct: 327 LQVRL 331


>UniRef50_UPI00015614CA Cluster: PREDICTED: hypothetical protein;
           n=3; Laurasiatheria|Rep: PREDICTED: hypothetical protein
           - Equus caballus
          Length = 651

 Score =  116 bits (279), Expect = 3e-24
 Identities = 81/281 (28%), Positives = 137/281 (48%), Gaps = 13/281 (4%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD-TSPEKKLYASYIKAKS 231
           W +++ +W      +    R  V +G+P   RG VW LL  ++    E K     +K ++
Sbjct: 76  WLKMLRDWGQYQGSKKMHKR--VFKGIPPQVRGRVWSLLLDLEKVKAENKGKYERMKEQA 133

Query: 232 ACE----KVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
                  K I  D+ RT+  H  + ++ G+ Q++LF+V+ AYS+++ EVGYCQG   +V 
Sbjct: 134 RLFSDDIKQIDLDVNRTFRNHIMYWDRYGIKQQALFHVLAAYSVYNTEVGYCQGMSEVVA 193

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           +LLM + EE+AF  L ++M  ++H M   F P   +L       E ++ + LP L  H  
Sbjct: 194 VLLMFLGEEDAFWALAQLMVSERHAMHGFFVPGFPKLLRFQAHHEQVLTKGLPKLKQHLD 253

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            +   T +Y                L  ++ D ++ EG  ++  +A  +L L K  LL L
Sbjct: 254 EEHMCTGIYTAKWFLQCFIGRTPFSLTLKLWDTYILEGERVLTAMAYTVLKLHKKRLLKL 313

Query: 406 DMESILKYIQKEL--PLKAEADQAAFMNLAYSVKVNPKKMK 444
            +E + +++Q  L  P   E D A   +L  S+ V  ++MK
Sbjct: 314 PLEGLREFLQDGLCQPWALE-DDAVLRHLQASM-VELQRMK 352


>UniRef50_A7SA57 Cluster: Predicted protein; n=7; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 303

 Score =  116 bits (279), Expect = 3e-24
 Identities = 65/229 (28%), Positives = 113/229 (49%), Gaps = 6/229 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK---LYASYI-K 228
           W  +++N+E    ++ + +R+  R+G+P   RG+ W+ L+G     EK+   L+     K
Sbjct: 65  WLEMLNNYEKWITKKYKKLRERCRKGIPPAVRGLAWRHLSG-SIKMEKQNPNLFEDLASK 123

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
                E  I +D+ R +P H+ F +  G GQ+ LF V+KAYSL+D   GYCQ    +V +
Sbjct: 124 PSPEWENTIEKDLCRVFPYHEQFTDTGGQGQKDLFRVLKAYSLYDSHTGYCQAMAPVVAV 183

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LLM M  EEAF  LV I  ++ +   + P +  + L       L+ + +P +  H +   
Sbjct: 184 LLMHMTAEEAFWCLVMICSKY-LPGYYGPKLEAIQLDGAIFGGLLSKTVPHISKHMKQHH 242

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTL 397
               +Y                   R+ D+F  EGI+++F+  +A++ +
Sbjct: 243 IDPLMYMTEWYMCLLARNLPFATVLRVWDMFFCEGIKVLFRTTIAIMKI 291


>UniRef50_Q4DFJ7 Cluster: Rab-like GTPase activating protein,
           putative; n=2; Trypanosoma cruzi|Rep: Rab-like GTPase
           activating protein, putative - Trypanosoma cruzi
          Length = 341

 Score =  116 bits (278), Expect = 4e-24
 Identities = 76/240 (31%), Positives = 117/240 (48%), Gaps = 13/240 (5%)

Query: 172 LWGRLVSNWE-SEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP----EK-KLYAS 225
           +W R++  W+ + +K++ +    L R+G+P   R IVW LL     S     EK  +  S
Sbjct: 57  MWARVLVRWDHTSYKKKKK----LAREGIPQSMRRIVWPLLLNSHESSGLSHEKYHVLKS 112

Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
              A      VI RD+ RT+P H +F   DG+GQ  L  +++AY+    EVGY QG  F+
Sbjct: 113 RPPADPEVFAVIERDLGRTFPAHQWFARADGVGQTKLRGILRAYANIHPEVGYVQGMAFL 172

Query: 286 VGLLLMQM-PEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHV 342
              LL+ +  EE+ F     +M+  +H +  MF P    L +  +QL+ L+Q     L  
Sbjct: 173 ASTLLLHIEDEEDTFWAFFSLMRNPKHSIWKMFTPGFPSLYMRFYQLKKLMQRNCMSLFR 232

Query: 343 HFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
             ++      +YA               L  RI D+FL EG +I+F+VA+AL  L +  L
Sbjct: 233 LLEAFHVEPEVYATHWFLTLFSYCLEFDLLSRIWDMFLCEGWKIIFRVAIALFLLCEKTL 292


>UniRef50_Q4KMP7 Cluster: TBC1 domain family member 10B; n=23;
           Theria|Rep: TBC1 domain family member 10B - Homo sapiens
           (Human)
          Length = 668

 Score =  116 bits (278), Expect = 4e-24
 Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 17/242 (7%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
           W  + SNW+    RR Q V+   R+G+P   R   WQ L+     ++ +P K        
Sbjct: 195 WLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP 254

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
                  VI +D+ R +P H+ F  + G GQ+ L+ ++KAY+++  + GYCQ    +  +
Sbjct: 255 GDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAV 314

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN-----LVQELLPDLHVH 343
           LLM MP E+AF  LV+I       D + P     GL   QL+      L++   P  H H
Sbjct: 315 LLMHMPAEQAFWCLVQIC------DKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRH 368

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
            + Q     LY                   R+ D+F  EG++I+F+VAL LL  TLG  +
Sbjct: 369 LRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVE 428

Query: 402 LL 403
            L
Sbjct: 429 KL 430


>UniRef50_Q9U2D8 Cluster: Putative uncharacterized protein; n=4;
           Bilateria|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 1085

 Score =  115 bits (276), Expect = 7e-24
 Identities = 71/255 (27%), Positives = 129/255 (50%), Gaps = 10/255 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAK 230
           W +++  W+S    +   + D + +G+P   R ++W  L G +    ++  +YA  +   
Sbjct: 569 WLKMIEVWKSGGPSKK--MEDRIWKGIPEKLRIVIWPRLLGAERLKHERRDVYAELLLRA 626

Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
               K I++   DI RTY +H  F+++  + Q+SL NV+ AYS+ + EVGYCQG   I  
Sbjct: 627 RLVSKDIKQIDLDINRTYRDHLAFRKRYDVKQKSLLNVLAAYSMFNTEVGYCQGMSQIAA 686

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           L LM + EE+AF  L ++M   +H M   F P   +L       + ++++  P ++ H +
Sbjct: 687 LFLMYLDEEDAFWSLHQLMVSPKHTMHGFFVPGFPKLQRYEEHFKRVLKKYKPRVYKHLE 746

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            Q     +Y                LA R+ DVFL EG  I+  +A  ++ + + ++   
Sbjct: 747 KQDI-PYIYLTKWWFGCFLDRVPFSLALRLWDVFLVEGDCILIAMAYNIMKMHEKNVRKH 805

Query: 406 DMESILKYIQKELPL 420
           +MES +++IQ ++ +
Sbjct: 806 NMESFMEFIQNDIAI 820


>UniRef50_Q7RN69 Cluster: Homo sapiens dJ846D11.1, putative; n=4;
           Plasmodium (Vinckeia)|Rep: Homo sapiens dJ846D11.1,
           putative - Plasmodium yoelii yoelii
          Length = 891

 Score =  115 bits (276), Expect = 7e-24
 Identities = 74/254 (29%), Positives = 122/254 (48%), Gaps = 17/254 (6%)

Query: 175 RLVSNWESEWKRRNQWVRDL--------VRQGVPHHFRGIVWQLLAGVDT---SPEKKLY 223
           R++  W S   R   W +          V++G+P  +R  VW  +    +     EKK Y
Sbjct: 160 RILEKWSSMIDRNINWFKKAHKTTFLRRVKRGIPQKYRWKVWMHITNSTSLINKFEKKYY 219

Query: 224 ASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
             Y K  S    +I  DI+RT+PE   F   D   Q+ L+ ++ AY+ ++  VGYCQG  
Sbjct: 220 YLY-KKTSNYSNLIYIDISRTFPELLIF---DKYAQDQLYRILNAYANYESSVGYCQGMN 275

Query: 284 FIVGLLLM--QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLH 341
           FIVGLLL+     E E F VLV +M  + +++ +K     L   ++  E +++  +PDL+
Sbjct: 276 FIVGLLLIVSNFNELETFCVLVTLMDNYHLKNFYKEKFPLLNRFIYVFEKILKFEIPDLY 335

Query: 342 VHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKND 401
            HF+++     +Y                    I D   S  I+++  +++ALL + KN 
Sbjct: 336 QHFKNEEVHPPVYLHQWFLTLFIASLPIKSVIVIWDYLFSTSIKMILIISIALLKILKNY 395

Query: 402 LLSLDMESILKYIQ 415
           L+  + E ILK ++
Sbjct: 396 LIKNNFEKILKLLK 409


>UniRef50_Q8SU09 Cluster: Similarity to HYPOTHETICAL TRANSMEMBRANE
           PROTEIN YADA_SCHPO; n=2; Apansporoblastina|Rep:
           Similarity to HYPOTHETICAL TRANSMEMBRANE PROTEIN
           YADA_SCHPO - Encephalitozoon cuniculi
          Length = 320

 Score =  114 bits (274), Expect = 1e-23
 Identities = 71/244 (29%), Positives = 118/244 (48%), Gaps = 6/244 (2%)

Query: 173 WGRLVSNWES--EWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAK 230
           W  L++  ++  E  RR++  R L+ QG+P   +  +W L     +  +   Y++ I  K
Sbjct: 48  WYDLITRCKNSGERLRRSESARRLIYQGIPLSLKYRLWGLFTQRTSDFD---YSALISRK 104

Query: 231 SACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLL 290
           S  E  I  D+ RT+  H  F  + G GQ  LFN++ AYS ++ EVGYCQG      LLL
Sbjct: 105 SGYEHQIHVDVQRTFRRHFLFSREYGRGQCELFNILTAYSNYNPEVGYCQGMSSAAALLL 164

Query: 291 MQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFS 350
           M  PEEEAF +LV I++ + +  +F   ++++       + + + L+P+++ H   Q+  
Sbjct: 165 MYFPEEEAFEMLVSIIRNNHLEALFDKKLSKVPRVQKIQDEIFKALIPEVYSHLLHQNID 224

Query: 351 TSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESI 410
             +YA               L  R+ D FL     I    A  +L      +L L  E +
Sbjct: 225 IGVYA-VGWYLTLFTRFDIKLVLRMWDFFLFFDFSIFMFFAAGILKFFAMGILELQGEQL 283

Query: 411 LKYI 414
           +++I
Sbjct: 284 IEFI 287


>UniRef50_UPI0000F1DA62 Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 849

 Score =  113 bits (273), Expect = 2e-23
 Identities = 73/242 (30%), Positives = 115/242 (47%), Gaps = 17/242 (7%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
           W  +  NW+    RR Q V+   R+G+P   R   WQLL+     +D++P K       +
Sbjct: 298 WLDMFRNWDKWVSRRFQKVKMRCRKGIPSSLRAKAWQLLSNSQELLDSNPGKFEELEQEQ 357

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
                  +I +D+ R +P H+ F  + G GQ+ L+ ++KAY+++  + GYCQ    +  +
Sbjct: 358 GDPKWLDIIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTVYRPDEGYCQAQAPVAAV 417

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLE-----NLVQELLPDLHVH 343
           LLM MP E+AF  LV+I ++      F P     GL   QL+     +L++ + P  + H
Sbjct: 418 LLMHMPAEQAFWCLVQICEK------FLPGYYSAGLEAIQLDGEIFFSLLRRVCPMAYRH 471

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
            +       LY                   R+ D+F  EG++IVF+V L LL   LG  D
Sbjct: 472 LKKFKIDPILYMTEWFMCIFSRTLPWSCVLRVWDMFFCEGVKIVFRVGLVLLKQMLGSVD 531

Query: 402 LL 403
            L
Sbjct: 532 KL 533


>UniRef50_A6RG76 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 755

 Score =  113 bits (271), Expect = 3e-23
 Identities = 68/197 (34%), Positives = 100/197 (50%), Gaps = 5/197 (2%)

Query: 109 LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXH-EVETRPTPGTNGEE 167
           LLA+LE+EN  +  + K+ S     SR                        PTP    E 
Sbjct: 129 LLARLEQENNALAGNPKSGSHVRKDSRPPSLHQIRKLVDEPQRASLRFSQLPTPQMT-EL 187

Query: 168 DLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI 227
           D W+    LV+++     R      + +R GVP   RG+VW  LAG   S     +A   
Sbjct: 188 DFWAA---LVADYNHTASRLPTLTSNKIRAGVPPPLRGVVWPSLAGARDSDLLDEFARLT 244

Query: 228 KAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
              S  E +I +DI R++P  + F++ +G GQ+ L  V++++SL+D ++GYCQG GF+VG
Sbjct: 245 GVTSPYEGLIGKDIGRSFPSVEMFRDPNGEGQQMLGRVLRSFSLYDEKIGYCQGLGFVVG 304

Query: 288 LLLMQMPEEEAFAVLVK 304
            LLM M + EAF VLV+
Sbjct: 305 PLLMHMSDAEAFCVLVR 321


>UniRef50_A7SQE4 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 291

 Score =  111 bits (267), Expect = 8e-23
 Identities = 72/237 (30%), Positives = 119/237 (50%), Gaps = 8/237 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA-KS 231
           WG ++    S   ++++ ++  VR+GVP   R  VW  ++G      KKL   Y    +S
Sbjct: 35  WGSVLKG--SSKVKKSRKIKRFVRKGVPSSHRAQVWMDISGA-RKRMKKLPGYYQSLLES 91

Query: 232 ACEKVIRR----DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
             + ++R     DI RT+PE+ +F       ++ L N++ AY++H+ ++GYCQG  +I G
Sbjct: 92  ELDDIVRNSILTDIDRTFPENIYFGSSSDSLKQKLKNILVAYAVHNPKIGYCQGLNYIAG 151

Query: 288 LLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQ 347
           LLL+ +  EE    L++ M   R+ D +   M  L +    L  LV+  LP LH H +S 
Sbjct: 152 LLLLIIKTEEPAFWLLEAMMMKRLPDYYAKDMMGLQVEQEVLSELVKIKLPTLHHHIESI 211

Query: 348 SFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
             S S+++                  RI D    EG +I+ +VA+ LL L ++ LL+
Sbjct: 212 GLSYSIFSTKWFICLYIDVLPVETVLRIWDSLFYEGSKILLRVAITLLALHQDKLLA 268


>UniRef50_UPI0000E475AE Cluster: PREDICTED: similar to mKIAA1108
           protein, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to mKIAA1108 protein,
           partial - Strongylocentrotus purpuratus
          Length = 904

 Score =  110 bits (264), Expect = 2e-22
 Identities = 58/141 (41%), Positives = 77/141 (54%), Gaps = 9/141 (6%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLA---------GVDTSPEKKLYASYIKAKSACEKVIRRDI 241
           +  L ++GVP   RG +W +L+         G    PE + Y+  IK  +  +  I  D+
Sbjct: 763 INKLFKEGVPKTRRGDIWMMLSEQHLLRMVPGASQIPESEPYSELIKHLTTHQHAILIDL 822

Query: 242 ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
            RTYP H +F    G GQ SLFN++KAYSL D EVGYCQG  F+ G+LLM M E  AF +
Sbjct: 823 GRTYPNHPYFSNALGHGQLSLFNLLKAYSLLDGEVGYCQGLSFVAGILLMHMEEPAAFKM 882

Query: 302 LVKIMQQHRMRDMFKPSMAEL 322
           L  +M     R  +KP M  L
Sbjct: 883 LTYLMFSWGFRSQYKPDMTAL 903


>UniRef50_UPI00015B5228 Cluster: PREDICTED: similar to gh regulated
           tbc protein-1; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to gh regulated tbc protein-1 - Nasonia
           vitripennis
          Length = 369

 Score =  109 bits (263), Expect = 2e-22
 Identities = 73/234 (31%), Positives = 114/234 (48%), Gaps = 8/234 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAK 230
           W R+++ W +      + VR+  R+G+P   R   W  L G  +       LY   IK  
Sbjct: 67  WIRMLNKWSTFMSTNYRKVRERCRKGIPPSVRPRAWLNLCGGALLLKENPNLYQELIKRP 126

Query: 231 SACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
              + +  I++D+ R +P H+ F E +  GQ+ LF ++KAYS+ + +VGYCQ    I   
Sbjct: 127 GDPKYIDDIKKDLHRQFPHHEMFVE-NAPGQQELFQILKAYSILNSKVGYCQAQAPIAAF 185

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LLM MP  +AF  LV I  ++ +   +   M  L      L  L++++ P  + H + Q 
Sbjct: 186 LLMHMPAVQAFWCLVAICDKY-LVGYYSHGMETLQRDGDILFALLKKVSPVTYKHLKKQK 244

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKN 400
               LY                   RI D+FL EG++I+FKVAL LL  +LG++
Sbjct: 245 MEPILYMTEWFLCVYTRTLPWESILRIWDMFLCEGVKIIFKVALVLLKGSLGRS 298


>UniRef50_A7AST0 Cluster: TBC domain containing protein; n=1;
           Babesia bovis|Rep: TBC domain containing protein -
           Babesia bovis
          Length = 229

 Score =  109 bits (263), Expect = 2e-22
 Identities = 59/199 (29%), Positives = 101/199 (50%), Gaps = 7/199 (3%)

Query: 204 RGIVWQLLAGVDTSPEKK---LYASYIKAKSACEK--VIRRDIARTYPEHDFFKEKDGLG 258
           RGI+W++ A  +   E+    LY   +   + CE    I+ D+ RT+P H  F E +   
Sbjct: 24  RGIMWKIWAHTEEYKERSPRGLYTHLVNF-NMCEHDAAIKNDVNRTFPNHSVFNESN-YT 81

Query: 259 QESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPS 318
           Q+ LFNV++AY++++ +VGYCQG  FI G+L++ M EE+AF  ++ +M++H +   F P 
Sbjct: 82  QQILFNVLRAYAMYNPDVGYCQGMAFIAGMLVIYMDEEDAFYTMISVMEKHDINKFFLPQ 141

Query: 319 MAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDV 378
           M  L      L+  +   +  L++H Q  + +T + A                A  + D 
Sbjct: 142 MKHLEKYCHVLDLYLNRKMNQLYLHLQKNNVNTKIIASQWFLTLFTYSFSVETAAILWDA 201

Query: 379 FLSEGIEIVFKVALALLTL 397
            L+     V  +A+A+  L
Sbjct: 202 ILAMEDNYVLSIAVAIFKL 220


>UniRef50_Q8I379 Cluster: Putative uncharacterized protein PFI0345w;
           n=1; Plasmodium falciparum 3D7|Rep: Putative
           uncharacterized protein PFI0345w - Plasmodium falciparum
           (isolate 3D7)
          Length = 1133

 Score =  109 bits (262), Expect = 3e-22
 Identities = 69/225 (30%), Positives = 108/225 (48%), Gaps = 7/225 (3%)

Query: 195 VRQGVPHHFRGIVWQLLAGVDTSPEK--KLYASYIKAKSACEKVIRRDIARTYPEHDFFK 252
           V++G+P  +R  +W  +        K  K Y    K KS    +I  DI+RT+PE   F 
Sbjct: 305 VKRGIPQKYRWKIWFHITNAKNLYNKFQKKYYYLSKKKSNYTNLILIDISRTFPELLIF- 363

Query: 253 EKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM--QMPEEEAFAVLVKIMQQHR 310
             D   Q+ L+ V+ AYS ++  VGYCQG  F+VGLLL+     E E F VLV +M  + 
Sbjct: 364 --DKYAQQQLYRVLNAYSNYEPSVGYCQGMNFLVGLLLIISNFNELETFCVLVSLMNNYY 421

Query: 311 MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXP 370
           ++D +K     L   ++  E ++Q  +PDL  HF ++     +Y                
Sbjct: 422 LKDFYKEKFPLLNRFIYLFERIMQNEIPDLVDHFNNEEVYPPVYLHQWLLTLFIASLPIK 481

Query: 371 LACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQ 415
               I D   S  I+ +  +++ALL + K+ L+    E ILK ++
Sbjct: 482 SVIVIWDYLFSTSIKKIIIISVALLKILKSYLMKHKFEKILKLLK 526


>UniRef50_Q7PPV8 Cluster: ENSANGP00000014519; n=5; Coelomata|Rep:
           ENSANGP00000014519 - Anopheles gambiae str. PEST
          Length = 384

 Score =  109 bits (262), Expect = 3e-22
 Identities = 70/282 (24%), Positives = 130/282 (46%), Gaps = 10/282 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAK 230
           W ++  NW++   + N  +R  V +G+P   R  +W+ L  +D    +   +Y   +   
Sbjct: 78  WVKMHKNWDAAATKEN--LRRRVMKGIPDRMRSAIWRKLLDLDRQIRENGGMYDRMLDCA 135

Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
                 IR+   D+ R +  H F++E+  + Q+SLF V+ AYS+++ EVGYCQG   +  
Sbjct: 136 RRHSPDIRQIDFDVNRQFRNHVFYRERYSVKQQSLFRVLAAYSMYNTEVGYCQGMSTVAA 195

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           +LLM   EE+ F  L  +M  Q++ M  ++     +L   +   + ++ + LP +  H  
Sbjct: 196 VLLMYFDEEDTFWALDVLMTNQRYAMHGLYIVGFPKLMRFLAHHDRILTKCLPKVKKHLD 255

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
                + LY+               L  R+ D+++  G  ++  +A  +L + K  LL +
Sbjct: 256 KHEVHSVLYSLKWFFVIFIERIPFSLCLRVWDIYMMYGERVLTAMAYTILKVHKTKLLRM 315

Query: 406 -DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
            DM+ +  ++Q  L  +   D    +    S     KK+K L
Sbjct: 316 KDMDQVTDFLQTSLHKQFGYDDDYVIKALQSSMDELKKLKLL 357


>UniRef50_A5K6E2 Cluster: TBC domain containing protein; n=2;
           Plasmodium|Rep: TBC domain containing protein -
           Plasmodium vivax
          Length = 1220

 Score =  109 bits (262), Expect = 3e-22
 Identities = 83/280 (29%), Positives = 127/280 (45%), Gaps = 17/280 (6%)

Query: 173 WGRLVS---NWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK--KLYASYI 227
           W  +++   NW  +   R  ++R  V++G+P  +R  VW  +        K  K Y    
Sbjct: 204 WSSMINRDINWFMK-THRTTFLRR-VKRGIPQKYRWKVWFQITNSKILLNKFQKKYYFLS 261

Query: 228 KAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
           K KS    +I  DI+RT+PE   F   D   QE LF ++ AYS  +  VGYCQG  F+VG
Sbjct: 262 KKKSNYTNLIMIDISRTFPELLIF---DKYAQEQLFRILNAYSNFEPSVGYCQGMNFLVG 318

Query: 288 LLLM--QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           LLL+     E E F VLV +M  + +++ +K     L   ++  E ++Q  +PDL  HF 
Sbjct: 319 LLLIVSNFNEIETFCVLVSLMNNYHLKEFYKEKFPLLNRYIYLFEKILQCEVPDLVDHFN 378

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            +     +Y                    I D   S  I+ +  +++ALL + K+ L+  
Sbjct: 379 REEVFPPVYLHQWLLTLFIASLPIKSVIVIWDYLFSTSIKTILIISVALLKILKSYLMKH 438

Query: 406 DMESILKYIQKELPLKAEADQAAFMNL----AYSVKVNPK 441
             E ILK + K L      D      L    + SV +NP+
Sbjct: 439 KFEKILKLL-KSLKYNESNDDILIAKLLIKKSESVNLNPE 477


>UniRef50_UPI00015B478A Cluster: PREDICTED: similar to MGC155085
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to MGC155085 protein - Nasonia vitripennis
          Length = 621

 Score =  109 bits (261), Expect = 4e-22
 Identities = 76/267 (28%), Positives = 126/267 (47%), Gaps = 9/267 (3%)

Query: 186 RRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA-----KSACEKVIRRD 240
           R  + VR+L  +G+P   RG VW+L      +   +LY   ++      +S     IR D
Sbjct: 350 RDTRRVRELWWRGLPPSIRGRVWRLAIPNSLNVTSQLYRLCLERAMTSPQSEALAAIRLD 409

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
           +ART+P    F+E   L  ESL  V+ AY+L+  ++GY QG  FI  +L + M   +AF 
Sbjct: 410 VARTFPTLCVFQEGGPLS-ESLQAVLAAYALYRPDIGYVQGMSFIGAVLALNMDAPDAFT 468

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
               ++ +      F      +G+        +   LP L+ HF +   S  LY      
Sbjct: 469 CFANLLNRPCHLAAFSLDQHRMGVYYKAYSAALANRLPKLYAHFLAAGLSPDLYLLDWLY 528

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
                     +ACR+ D+FL +G E +F+ AL +L L +++LL +D     +++ + LP 
Sbjct: 529 TIYAKAMPLDVACRVWDLFLRDGEEFLFRAALGVLHLYQDELLGMDFVRAAQFLTR-LPE 587

Query: 421 KAEADQAAFMNLA-YSVKVNPKKMKKL 446
              AD A F +++  S  V P   +++
Sbjct: 588 NMHAD-ALFNSISQMSTSVGPTSFQQM 613


>UniRef50_A1CI02 Cluster: GTPase activating protein (Gyp5),
           putative; n=7; Eurotiomycetidae|Rep: GTPase activating
           protein (Gyp5), putative - Aspergillus clavatus
          Length = 904

 Score =  109 bits (261), Expect = 4e-22
 Identities = 66/188 (35%), Positives = 100/188 (53%), Gaps = 6/188 (3%)

Query: 234 EKVIRRDI-ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQ 292
           EK IRRD+ ART     F  + +   QESLF + KAY+L+D  VGY QG  FIV  LL  
Sbjct: 514 EKAIRRDLGARTSYSRYFVSQGN---QESLFGLCKAYALYDEAVGYAQGMNFIVMPLLFN 570

Query: 293 MPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTS 352
           M E EAF ++VK+M ++ +R+MF   M  L   ++  E L+++  P L+ H + +     
Sbjct: 571 MDEAEAFTLMVKLMNKYGLREMFIHDMPGLHRSLYVFERLLEDWEPALYCHLRRRGVHPQ 630

Query: 353 LYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIE-IVFKVALALLTLGKNDLLSL-DMESI 410
           LYA               L  RI D+   EG+E  + K A+A++      LL++ DM  +
Sbjct: 631 LYATQWFLTLFAYRFPLQLVLRIYDLIFEEGLESAILKFAIAIMRRNAQTLLTMKDMTPL 690

Query: 411 LKYIQKEL 418
             ++++ L
Sbjct: 691 TTFLKERL 698



 Score = 39.5 bits (88), Expect = 0.40
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 170 WSLWGRLVSNWESEWKRRN-QWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIK 228
           W LW +LV++     K  N + +   +++G+P   RG++WQ+LA       +++Y   + 
Sbjct: 374 WELWQQLVNHGPQALKGANSEELNAAIKRGIPQTIRGVIWQILADSRNPELEEVYRELVV 433

Query: 229 AKSACEK 235
             +  EK
Sbjct: 434 RGTDKEK 440


>UniRef50_Q4P413 Cluster: Putative uncharacterized protein; n=1;
            Ustilago maydis|Rep: Putative uncharacterized protein -
            Ustilago maydis (Smut fungus)
          Length = 1871

 Score =  107 bits (258), Expect = 1e-21
 Identities = 73/301 (24%), Positives = 136/301 (45%), Gaps = 11/301 (3%)

Query: 159  PTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP 218
            P+   + + +L   W  +++  +    ++++ V+ LVR GVP   R  VW  LA      
Sbjct: 894  PSLPPSDDPELREKWLAVLAENDVAAAQKSRKVKKLVRTGVPGSVRREVWLFLANASVRR 953

Query: 219  EKKLYASYIKA---------KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAY 269
               L+    K          K    + I +D+ RT P+H  F   +  G+  L  ++K+Y
Sbjct: 954  RPGLFEQLCKTSQGTKGKRGKEEAYETIEKDLHRTLPDHRLFMGDNATGRADLEGILKSY 1013

Query: 270  SLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQL 329
               +  +GY QG G + G  L+QMP E+AF +L  +++  +M + +   M +L +     
Sbjct: 1014 VHFNPMLGYTQGMGLLAGFALIQMPAEDAFWLLCAVLRNPQMEEYYSAGMKQLHVDSVVF 1073

Query: 330  ENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFK 389
            +NL++ + P+L   F+     + ++                   R+ DVF  EG   + +
Sbjct: 1074 DNLLKTMDPELQARFEEAGLQSIMFTPNWFLALFTRVLPWTTLLRVWDVFFYEGPTWMLR 1133

Query: 390  VALALLTLGKNDLLSLD-MESILKYIQKEL-PLKAEADQAAFMNLAYSVKVNPKKMKKLE 447
            VALA++ + +  L+      +  + +Q  L P          +N A+SVK+   +M+KL 
Sbjct: 1134 VALAIVRILREQLVDQQACPTAGEMLQLLLHPPPHNLTVENVLNCAFSVKLKDGEMRKLS 1193

Query: 448  K 448
            +
Sbjct: 1194 R 1194


>UniRef50_UPI000155D1B1 Cluster: PREDICTED: similar to TBC1
           (tre-2/USP6, BUB2, cdc16) domain family, member 1; n=1;
           Ornithorhynchus anatinus|Rep: PREDICTED: similar to TBC1
           (tre-2/USP6, BUB2, cdc16) domain family, member 1 -
           Ornithorhynchus anatinus
          Length = 1090

 Score =  107 bits (257), Expect = 1e-21
 Identities = 50/112 (44%), Positives = 70/112 (62%)

Query: 244 TYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLV 303
           T+P H +F  + G GQ SL+N++KAYSL D+EVGYCQG  F+ G+LL+ M EE+AF +L 
Sbjct: 721 TFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGVLLLHMAEEDAFRMLK 780

Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
            +M    +R  + P M  L + M+QL  L+ +   DLH H +      SLYA
Sbjct: 781 FLMFDAGLRKQYCPDMTILQIQMYQLSRLLHDYHRDLHDHLEEHEIGPSLYA 832


>UniRef50_O44873 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 445

 Score =  107 bits (257), Expect = 1e-21
 Identities = 78/298 (26%), Positives = 143/298 (47%), Gaps = 18/298 (6%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE---KKLYASYIKA 229
           W +++ NW      + + V++  R+G+P   RG  W+ L+G     E    +    Y   
Sbjct: 149 WIQMLDNWRYFMDEKFELVKNRCRKGIPPSLRGRAWKYLSGATYQMEVSSNRFVFDYCVK 208

Query: 230 KSACEKV---IRRDIARTYPEHDFFKE--KDGL-GQESLFNVMKAYSLHDREVGYCQGSG 283
           ++   K    I++D++R +PEH+ F    K G  G+  LF+++KA+++   E GYCQG  
Sbjct: 209 QAGDPKWNDDIQKDLSRQFPEHEMFARVGKYGNNGKNDLFDLLKAWTILHPEEGYCQGQA 268

Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
            I  +LLM MP  +AF   V+I  ++ +   +   +  +      L  L+++     + H
Sbjct: 269 PIAAVLLMHMPVRDAFYCFVQICHKY-LPGYYSSGLEAVQTDGDILTKLIKDRSKLTYRH 327

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
           F++     +LY               P   R+ D+FL EG++I+FKVAL LL  G     
Sbjct: 328 FKANGVDPALYMIEWFMCCFCRTLPWPTVLRVWDMFLCEGVKILFKVALVLLKFGIGTPS 387

Query: 404 SL----DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
            +    DM +I+  + + LP++   ++     ++    +N   M+KL   +  +KT++
Sbjct: 388 QIKQYPDMPAIVTRL-RNLPVEIMEEEFLVQKIS-ETNLNDADMEKL--HFGAMKTRQ 441


>UniRef50_Q38A99 Cluster: GTPase activating protein, putative; n=1;
           Trypanosoma brucei|Rep: GTPase activating protein,
           putative - Trypanosoma brucei
          Length = 340

 Score =  107 bits (256), Expect = 2e-21
 Identities = 73/238 (30%), Positives = 113/238 (47%), Gaps = 11/238 (4%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA-----GVDTSPEKKLYASYI 227
           W + +  W+     +    + L R GVP   R  VW LL       ++   +  L  S  
Sbjct: 56  WSKALLRWDGCAHMKK---KKLCRVGVPQSQRKTVWPLLLMTYGWQLEKYGDYHLLMSQQ 112

Query: 228 KAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
              +A  ++I RD+ RT+P H  F +    GQ  L ++++AY+  + E GY QG GF+VG
Sbjct: 113 PRDAAMFEIIERDLGRTFPTHRLFNKPGSTGQMGLRSILRAYANLNPETGYVQGMGFLVG 172

Query: 288 LLLMQMPEEEA-FAVLVKIMQQHR--MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
            LL+Q+ +EE+ F+  V IM+  R  M  ++ P    L + + QL+ L+      L    
Sbjct: 173 TLLIQIGDEESTFSAFVSIMENPRYSMAKLYAPGFPLLFVRLHQLQKLLGRHCKKLLKRL 232

Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
                  S +A               L  RI D+FL EG +I+ +VA+ALL L K+ L
Sbjct: 233 MEYGIELSTFAANWYLTLFAYHFNFGLLSRIWDMFLCEGWKIIHRVAIALLLLHKSAL 290


>UniRef50_UPI00005A12CF Cluster: PREDICTED: similar to USP6
           N-terminal like protein (Related to the N terminus of
           tre) (RN-tre); n=3; Canis lupus familiaris|Rep:
           PREDICTED: similar to USP6 N-terminal like protein
           (Related to the N terminus of tre) (RN-tre) - Canis
           familiaris
          Length = 672

 Score =  105 bits (252), Expect = 5e-21
 Identities = 72/250 (28%), Positives = 117/250 (46%), Gaps = 11/250 (4%)

Query: 195 VRQGVPHHFRGIVWQLLAGVDTSPEKKL--YASYIKAKSACEKVIRR---DIARTYPEHD 249
           V + VP   RG VW  L  +D    +    Y    +A     + I     DI  T+  H 
Sbjct: 29  VYKRVPPQVRGQVWLRLLNIDQVKARNAGKYQEMKEAALVSSRDIMHIDLDINWTFSSHS 88

Query: 250 FFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM--Q 307
            F ++   G  +LF+V+ AYS++D E+GYCQG   I   +LM +PEE++F  L ++M   
Sbjct: 89  MFWDR--YGAVTLFHVLAAYSVYDTEMGYCQGMSEIAA-ILMFLPEEDSFWALAQLMTND 145

Query: 308 QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
           +H M   F P   +L       E ++Q  LPDL  H   +  ST +Y             
Sbjct: 146 RHAMHGFFVPGFPKLLRFQAHQERVLQRALPDLRKHMDEEQMSTGIYTPKWFLQCFLSRT 205

Query: 368 XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLK-AEADQ 426
              L  ++ DV++ +G  ++  +A  +L + +  LL L +E + +++Q  L    A  D+
Sbjct: 206 PFSLTLKLWDVYVLDGERVLTAMAYTILKVHRKRLLKLPLEGLQEFLQDSLAQPWALEDE 265

Query: 427 AAFMNLAYSV 436
           A   +L  S+
Sbjct: 266 AVLRHLRASM 275


>UniRef50_Q16V33 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 517

 Score =  105 bits (252), Expect = 5e-21
 Identities = 67/252 (26%), Positives = 122/252 (48%), Gaps = 12/252 (4%)

Query: 173 WGRLVSNWES-EWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKL--YASYIKA 229
           W ++ +NW S E K R Q     V +G+P   R  +W+LL  +D +  + +  Y   +K 
Sbjct: 85  WLKMRNNWTSAETKERLQ---RRVMKGIPDRLRAAIWKLLLNLDQTLAENVGVYDKMLKF 141

Query: 230 KSACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
                  IR+   D+ R +  H  ++E+  + Q+SLF V+ AYS+++ EVGYCQG   + 
Sbjct: 142 ARQYSPDIRQIDFDVNRQFRNHINYRERYSVKQQSLFRVLAAYSMYNMEVGYCQGMSTVA 201

Query: 287 GLLLMQMPEEEAFAVLVKIMQQHR--MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
           G+LLM   EE+ F  L  ++   R  M  ++     +L   +   + ++ + +P +  H 
Sbjct: 202 GVLLMYFDEEDTFWALNALLSNERYAMHGLYVEGFPKLMRFLQHHDKILTKCMPKVKKHL 261

Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
                 + LY+               L  R+ D+++  G  ++  +A  +L + K  LL 
Sbjct: 262 DKHGVDSVLYSLKWFFVIFIERIPFSLCLRVWDIYMLYGERVLTAMAYTILKVHKVKLLR 321

Query: 405 L-DMESILKYIQ 415
           + DM+ I +++Q
Sbjct: 322 MKDMDQITEFLQ 333


>UniRef50_Q9UPU7 Cluster: TBC1 domain family member 2B; n=36;
           Eumetazoa|Rep: TBC1 domain family member 2B - Homo
           sapiens (Human)
          Length = 868

 Score =  103 bits (248), Expect = 2e-20
 Identities = 65/235 (27%), Positives = 111/235 (47%), Gaps = 10/235 (4%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK---------LYASYIKAKSACEKVIRRDI 241
           +++L+R G+PH  R  VW+      T   K          L    ++ ++   K I  D+
Sbjct: 609 LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDL 668

Query: 242 ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
            RT P +  +      G + L NV+ A+S  + ++GYCQG   +V + L+ + +E+AF  
Sbjct: 669 LRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWC 728

Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
           LV I++    RD +  ++    +      +L+ E LP LH HF+      +L        
Sbjct: 729 LVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLV 788

Query: 362 XXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQ 415
                    +  +I D FL EG +++F+ ALAL    + ++L L D  SI KY++
Sbjct: 789 VFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLR 843


>UniRef50_UPI0000D558F9 Cluster: PREDICTED: similar to TBC1 domain
           family member 12; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to TBC1 domain family member 12 -
           Tribolium castaneum
          Length = 535

 Score =  103 bits (247), Expect = 2e-20
 Identities = 72/269 (26%), Positives = 122/269 (45%), Gaps = 22/269 (8%)

Query: 176 LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAK----- 230
           ++ NWE      N+  R+L  QG+P   RG VW+L  G + +   +LY   +        
Sbjct: 258 VLPNWEQ--MHTNKKTRELWWQGLPSSVRGKVWRLAIGNELNLTPQLYEICLSRAQNRLN 315

Query: 231 ----SACEK---------VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVG 277
               S CE          VI+ DI+RT+P    F+E  G   + L +++ AY  +  +VG
Sbjct: 316 SPEPSHCESDIDQESSMDVIQLDISRTFPHLCIFQE-GGPYSDILHSLLAAYVCYRPDVG 374

Query: 278 YCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELL 337
           Y QG  +I  +L++ M   +AF     ++ Q      F  +  ++         +    L
Sbjct: 375 YVQGMSYIAAILILNMEPFDAFICFANLLNQPLHLSAFTLNQEQMEAYYSAYNEVFSYNL 434

Query: 338 PDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTL 397
           P LH HF+    +  LY                +ACR+ D+FL +G E +F+ AL +L L
Sbjct: 435 PKLHAHFKEAKLTPDLYLLDWIYTIFAKAMPLDVACRVWDIFLRDGFEFIFRTALGILHL 494

Query: 398 GKNDLLSLDMESILKYIQKELPLKAEADQ 426
            ++ L+++D     +++ + LP    +DQ
Sbjct: 495 NQDILITMDFLHGAQFLTR-LPDDLSSDQ 522


>UniRef50_O60347 Cluster: TBC1 domain family member 12; n=11;
           Eumetazoa|Rep: TBC1 domain family member 12 - Homo
           sapiens (Human)
          Length = 775

 Score =  103 bits (246), Expect = 3e-20
 Identities = 83/314 (26%), Positives = 148/314 (47%), Gaps = 31/314 (9%)

Query: 172 LW-GRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPE--------- 219
           +W   ++ NWE    R  + VR+L  QG+P   RG VW L  G  ++ +PE         
Sbjct: 459 IWINEILPNWEV--MRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRA 516

Query: 220 KKLYASYIKAKS-------------ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVM 266
           K+ + S+ +  S             A  ++I+ DI+RT+P    F +K G   + L +++
Sbjct: 517 KERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIF-QKGGPYHDVLHSIL 575

Query: 267 KAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCM 326
            AY+ +  +VGY QG  FI  +L++ + E +AF     ++ +      F+   + +    
Sbjct: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYF 635

Query: 327 FQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEI 386
              E   +E L  L +HF+S S +  +Y                LACR+ DVF  +G E 
Sbjct: 636 ATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEF 695

Query: 387 VFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
           +F+  L +L L ++ LL +D   I +++ K LP    +++      A  ++ + KK  ++
Sbjct: 696 LFRTGLGILRLYEDILLQMDFIHIAQFLTK-LPEDITSEKLFSCIAAIQMQNSTKKWTQV 754

Query: 447 EKEYTVIKTKEQGD 460
               +V+K  ++GD
Sbjct: 755 FA--SVMKDIKEGD 766


>UniRef50_Q6CG19 Cluster: Similar to sp|P53258 Saccharomyces
           cerevisiae YGR100w MIC1 MAC1P interacting protein; n=1;
           Yarrowia lipolytica|Rep: Similar to sp|P53258
           Saccharomyces cerevisiae YGR100w MIC1 MAC1P interacting
           protein - Yarrowia lipolytica (Candida lipolytica)
          Length = 967

 Score =  102 bits (245), Expect = 4e-20
 Identities = 77/275 (28%), Positives = 127/275 (46%), Gaps = 11/275 (4%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG------VDTSPEKKLYASYIKAKSACEKVIRRD 240
           R Q    L+R G+P+  RG +W+L +G         S    L   Y    S   + I +D
Sbjct: 251 RQQTFYKLIRVGLPNRLRGEIWELTSGSLYLRLAHQSMYNDLLEEYEGKTSQATEEIEKD 310

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
           + R+ PE+  +++++G+ +  L  V+  YS  + +VGYCQ    ++   L+ M EE+AF 
Sbjct: 311 LNRSLPEYSAYQDEEGIAR--LRRVLTVYSWKNPDVGYCQAMNIVIAAFLIYMSEEQAFW 368

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
            L  ++    +   +  SM    L     E+LV++ +P L  H Q      S+ +     
Sbjct: 369 CL-NVLCDKMLPGYYSKSMYGTLLDQKVFESLVEKTMPLLWDHLQRCDVQLSVVSLPWFL 427

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKE--L 418
                      A RI+DVF  EG +++F+VALA+L +    LL  D + ++  I KE  L
Sbjct: 428 SIFINSMPLVFAFRIIDVFFLEGPKLLFQVALAILRINGERLLEADDDGLMIGIIKEYFL 487

Query: 419 PLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVI 453
            L   A   +      S+    + M    KE++VI
Sbjct: 488 TLDQSAHPTSKNEKLRSITKFQELMVVAMKEFSVI 522


>UniRef50_Q6PBU5 Cluster: Growth hormone-regulated TBC protein 1;
           n=11; Euteleostomi|Rep: Growth hormone-regulated TBC
           protein 1 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 356

 Score =  101 bits (242), Expect = 9e-20
 Identities = 65/214 (30%), Positives = 104/214 (48%), Gaps = 5/214 (2%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKA--KSACEKVIRRDIA 242
           RN  V+  VR+GVP+  R +VW + +G     ++    Y S +    +   E+ IR D+ 
Sbjct: 76  RNLKVKRYVRKGVPNEHRPLVWMVCSGAQEQMDRNPGYYQSLLDTHHEPKLEESIRTDLH 135

Query: 243 RTYPEHDFF-KEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
           RT+P++ +F K  +   Q++L+NV+ AY  H++ VGYCQG  FI G L++   +EE    
Sbjct: 136 RTFPDNIYFRKSAEPCLQQALYNVLVAYGHHNKAVGYCQGMNFIAGYLILVSKDEETSFW 195

Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
           L++ +    + D + P+M  L      L  LV+   P +    Q Q    +L        
Sbjct: 196 LMEALLSRILPDYYTPAMLGLKTDQEVLGELVRLKAPAVWKLMQDQGVMWTLVVSRWFIC 255

Query: 362 XXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
                       RI D    EG +I+F+VAL L+
Sbjct: 256 LFIDVLPVETVLRIWDCLFYEGSKILFRVALTLI 289


>UniRef50_O43048 Cluster: GTPase activating protein; n=2;
           Schizosaccharomyces pombe|Rep: GTPase activating protein
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 834

 Score =  101 bits (241), Expect = 1e-19
 Identities = 63/229 (27%), Positives = 117/229 (51%), Gaps = 9/229 (3%)

Query: 194 LVRQGVPHHFRGIVWQLLAG-----VDTSPE-KKLYASYIKAKSACEKVIRRDIARTYPE 247
           LVR  +P+  RG +W+L +G     ++ S E   L   Y    S   + I +D+ R+ PE
Sbjct: 216 LVRIELPNKLRGEIWELTSGSMYFRLENSDEYDHLLKVYSGQTSFSLEEIEKDLGRSLPE 275

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
           +  ++ ++G+   +L NV+ A+S  ++EVGYCQ    +   LL+   EE+ F ++ KI +
Sbjct: 276 YPAYQNEEGIN--ALRNVLVAFSWKNQEVGYCQAMNIVAAALLIHCTEEQTFFLMHKICE 333

Query: 308 QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
            + +   +  +M    +     E+LVQ  +P+LH HF S+    S+ +            
Sbjct: 334 DY-IPGYYSKTMYGTLIDQQVYESLVQRSMPNLHAHFVSKDIQLSIISLPWFLSLFLCTM 392

Query: 368 XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQK 416
             P A R++D F  EG  ++F++ +A+L   + +++    +++L  I K
Sbjct: 393 PLPYAFRLLDFFFLEGPRVLFQIGMAILYDNEAEIMKATEDTMLISILK 441


>UniRef50_A3GF95 Cluster: GTPase activating protein; n=5;
           Saccharomycetales|Rep: GTPase activating protein -
           Pichia stipitis (Yeast)
          Length = 938

 Score =  101 bits (241), Expect = 1e-19
 Identities = 67/219 (30%), Positives = 106/219 (48%), Gaps = 9/219 (4%)

Query: 194 LVRQGVPHHFRGIVWQLLAG-----VDTSPE-KKLYASYIKAKSACEKVIRRDIARTYPE 247
           L+R G+P+  RG +W+L  G     +D   E K++    +  KS     I +D+ R+ PE
Sbjct: 234 LIRVGLPNRLRGELWELCCGSMYLRLDYQDEYKEILEKNLHKKSLATDEIEKDLNRSLPE 293

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
           +  ++  +G+  E L  V+ AYS  + EVGYCQ    +V  LL+ M EE+AF  L  ++ 
Sbjct: 294 YAAYQSPEGI--ERLRRVLTAYSWKNPEVGYCQAMNIVVAALLIYMSEEQAFWAL-NLLC 350

Query: 308 QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
              +   +  +M    L     E+LVQ  +P L  H        S+ +            
Sbjct: 351 DRIVPGYYSKTMYGTLLDQRVFESLVQNTMPMLWDHITKNDIQLSVVSLPWFLSLYLSSM 410

Query: 368 XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLD 406
               A RI+DVF  +G + +F+VALA+L +   +LL  D
Sbjct: 411 PLVFAFRILDVFFLQGPQTLFQVALAILKINGEELLKTD 449


>UniRef50_Q4T9Z2 Cluster: Chromosome undetermined SCAF7482, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7482,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 404

 Score =  100 bits (240), Expect = 2e-19
 Identities = 63/215 (29%), Positives = 102/215 (47%), Gaps = 5/215 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYA-SYIKAKS 231
           W  ++ +W+    +R   VR   ++G+P   RG  W  L+G     E+       +  +S
Sbjct: 16  WLDMLGHWDKWIMKRFNKVRLRCQKGIPPALRGRTWLYLSGGKVKKEQNQGKFQELDHQS 75

Query: 232 ACEK---VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
              K   VI +D+ R +P H+ F  + G GQ+ LF V+KAY+L+  E GYCQ    I  +
Sbjct: 76  GDPKWVDVIEKDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAV 135

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LLM MP E+AF VLV+I +++ +   + P +  + L    L  L++ + P  + H +   
Sbjct: 136 LLMHMPAEDAFWVLVQICEKY-LPGYYSPGLEAIQLDGEILFALLRRISPVAYRHLEKHK 194

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG 383
               LY                   R+ D+FL +G
Sbjct: 195 IDPILYMTEWFMCAFSRTLPWASVLRVWDMFLCDG 229


>UniRef50_A0DZJ7 Cluster: Chromosome undetermined scaffold_70, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_70,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 320

 Score =  100 bits (239), Expect = 2e-19
 Identities = 68/289 (23%), Positives = 131/289 (45%), Gaps = 7/289 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP--EKKLYASYIKAK 230
           W +++          +  ++  +R+G+P   R ++W  LA +D      K+ Y   ++++
Sbjct: 34  WRKMIPKIPQLMANNDSKLKSRLRKGIPEGIRMLIWPCLAEIDQMKIQAKRTYKELVESQ 93

Query: 231 --SACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
             S  +  I  D+ RT+  +D  K  D +  +SLF V++A SL  +++GYCQG  ++ G 
Sbjct: 94  EISPHDSQITLDVMRTFQTNDLIK-MDTITSQSLFTVLRAISLTFQDMGYCQGLNYLAGS 152

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
            L+ M +E  +  L  ++ ++   D +      L    + L+ LV++ LPDLH  F   +
Sbjct: 153 FLLLMNDELVYWHLYSLLTKYGCLDTYINPTNTLKY-FYALDILVKQFLPDLHAKFTKFN 211

Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
                YA               +  R+ D+F  E  +  F+ +LA+L + K ++L+    
Sbjct: 212 IVPFYYAAEWFITLFSSILPMQIFLRVTDIFWHEHHKTTFRASLAILKIRKEEILTAKTM 271

Query: 409 SILKYIQKELPLKAEADQAAFMNLAYSVKVNPKK-MKKLEKEYTVIKTK 456
                I K+       D   F+ +A    +  KK ++K   ++   + K
Sbjct: 272 EQAITILKDQKFFNNYDPDKFIKIAMKDFIFSKKDLRKYYDQFAASQKK 320


>UniRef50_Q55TD4 Cluster: Putative uncharacterized protein; n=2;
            Filobasidiella neoformans|Rep: Putative uncharacterized
            protein - Cryptococcus neoformans (Filobasidiella
            neoformans)
          Length = 1106

 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 67/227 (29%), Positives = 108/227 (47%), Gaps = 10/227 (4%)

Query: 181  ESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASY-IKAKSACEKV--- 236
            + +WK  ++    L R+G+P  +RG +W   +G         YA   I  K     V   
Sbjct: 825  QEDWKTFSR----LTRRGIPLKYRGDIWAECSGAKDLMVPGEYAEILIVHKDDISPVMAD 880

Query: 237  IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQMPE 295
            I +D++RT+P + FF   DG G E L  V+ AYS ++  VGYCQG   +   LLL    E
Sbjct: 881  IEKDVSRTFPGNVFFGG-DGPGVEKLRRVLVAYSWYNPGVGYCQGMNMVAATLLLTHSDE 939

Query: 296  EEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
            E+AF +L+ I+ +    + F PS+         L  +V ++LP LH HF +     +   
Sbjct: 940  EQAFWILICIIDRLLPPNYFSPSLVGSRADQLVLSQIVAQILPKLHAHFVALGVDLASIT 999

Query: 356  XXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
                              R+ D+F  EG + +F+VA+A+L + + ++
Sbjct: 1000 FGWFLSLFTDCLPVETLFRVWDLFFVEGHDSIFRVAVAILKINEIEI 1046


>UniRef50_Q4PG28 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 785

 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 65/226 (28%), Positives = 113/226 (50%), Gaps = 10/226 (4%)

Query: 186 RRNQWVRDLVRQGVPHHFRGIVWQLLAG------VDTSPEKKLYASYIKAKSACEKVIRR 239
           R  Q++R LV+ G+P+  RG +W+L +G            + +   Y    S   + I +
Sbjct: 254 RYPQFLR-LVQVGLPNRLRGEIWELTSGSIYNRFAHAGEYQAILKRYEGITSTSTEEIEK 312

Query: 240 DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAF 299
           D+ R+ PE+  ++  +G+  E+L  V+ AYS  + E+GYCQ    +V  +L+ M EE+ F
Sbjct: 313 DLNRSLPEYPAYQTPEGI--ETLRRVLVAYSWKNPELGYCQAMNIVVAAILIYMSEEQCF 370

Query: 300 AVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
            +L  + ++  +   +  SM+   L     ENLVQ  LP +H HF       S+ +    
Sbjct: 371 WLLDTLCER-LLPGYYTQSMSGTLLDQKVFENLVQRTLPMIHEHFVKTDIQLSVASLPWF 429

Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
                       A RI+D F++ G +++F+V LA+L +   +LL +
Sbjct: 430 LSLYINSMPMIFAFRIVDCFMAMGPKVLFQVGLAILKINGEELLQV 475


>UniRef50_A7TSB1 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 957

 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 65/226 (28%), Positives = 110/226 (48%), Gaps = 9/226 (3%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG------VDTSPEKKLYASYIKAKSACEKVIRRD 240
           +N   + L+R G+P+  RG +W+L +G       ++   +K+        S     I +D
Sbjct: 235 KNHMFQKLIRVGLPNRIRGEIWELCSGSIYLRHANSGEYQKILRDNEGKTSQAIDEIEKD 294

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
           + R+ PE+  ++ ++G+G+  L NV+ AYS  + +VGYCQ    +V  LL+ M EE+AF 
Sbjct: 295 LKRSLPEYRAYQSEEGIGR--LRNVLTAYSWKNPDVGYCQAMNIVVAGLLIFMTEEQAFW 352

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
            L K+   + +   +  +M    L     E  V++ LP L  H        S+ +     
Sbjct: 353 CLTKLCDIY-VPGYYSKTMYGTLLDQKVFEAFVEDRLPILWKHIVQNDIQLSVISLPWFL 411

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLD 406
                      A RIMD+F   G + +F+VALA+L +  +DL S +
Sbjct: 412 SLFFTSMPLEYAFRIMDIFFLNGAKTLFQVALAVLKVNADDLSSAE 457


>UniRef50_A2EVI1 Cluster: TBC domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: TBC domain containing
           protein - Trichomonas vaginalis G3
          Length = 329

 Score = 99.1 bits (236), Expect = 5e-19
 Identities = 64/233 (27%), Positives = 108/233 (46%), Gaps = 7/233 (3%)

Query: 172 LWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYAS-YIKAK 230
           LW   + NW+ E K+    + +L+++G+P   RG VW  +  +++ P    Y   Y KA+
Sbjct: 39  LWSNYLKNWKREMKKSRDDIAELIKRGIPETMRGTVWSKILDIESLPADINYKDLYQKAE 98

Query: 231 SACEKV-IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
                + I +D+ R+ P+   F +K+ L  E L +++ AY  +D E+GY QG  FI GLL
Sbjct: 99  GQEFTITIDKDLTRSLPQIKSFSQKETL--ERLKHILYAYGQYDHELGYTQGENFIAGLL 156

Query: 290 LMQMPEEEAFAVLVKIMQQHRM--RDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQ 347
           +    EE AF   ++IM   R   R  F      L + +  L  L+Q+  P +     ++
Sbjct: 157 IHYQEEEIAFKSFIQIMNHPRCLHRFYFTEGFPRLDIAINILRILLQKKYPKILKKIDNE 216

Query: 348 SFSTSLYAXXXXXXXXXXXXXXP-LACRIMDVFLSEGIEIVFKVALALLTLGK 399
           +   S++A              P    RI + F+  G   +   AL + +  K
Sbjct: 217 NMPISMFATQWFMTAFMAFNWDPEFQMRIFERFIFYGTRGLLGFALVIFSRHK 269


>UniRef50_UPI0000588ED3 Cluster: PREDICTED: hypothetical protein
           isoform 2; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein isoform 2 -
           Strongylocentrotus purpuratus
          Length = 379

 Score = 98.7 bits (235), Expect = 6e-19
 Identities = 61/200 (30%), Positives = 104/200 (52%), Gaps = 9/200 (4%)

Query: 333 VQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL 392
           +Q+ +PDL+ HF      T ++A                   IMDVFLSEG+ +++ V+L
Sbjct: 1   MQDNVPDLYSHFVHIGIETHMFASQWFLTLFTAKFPLHTVFHIMDVFLSEGMIVIYHVSL 60

Query: 393 ALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEY 450
           ALL L K +LL  D E +LK+ +  LP K  +D++A   M +A S KV+ +K+KK EKE+
Sbjct: 61  ALLKLSKKELLGQDFEGVLKFFRVTLPKKYRSDESAVELMQVAMSTKVSQRKLKKYEKEF 120

Query: 451 TVIKTKEQGDIAVLRCLRQENRLLK-----QRVXXXXXXXXXXXXXXVRGQVDRAEGEEE 505
             +K +E+ +  V R  R+  ++++     +R               +  Q+D+     +
Sbjct: 121 YAMKEEEEREDPVDRLERENKQMMEANLHLERENDELAHELITHKLMMEKQLDKERDRAD 180

Query: 506 TFALDREVQALRRANVDMQQ 525
              L++E++ALR A  D ++
Sbjct: 181 --ELEKELKALRLALHDSEE 198


>UniRef50_Q76LY3 Cluster: KIAA1322; n=22; Deuterostomia|Rep:
           KIAA1322 - Mus musculus (Mouse)
          Length = 413

 Score = 98.7 bits (235), Expect = 6e-19
 Identities = 75/277 (27%), Positives = 127/277 (45%), Gaps = 30/277 (10%)

Query: 176 LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI-KAK---- 230
           ++ NWE+ W  +   VRDL  QG+P   RG VW L  G + +   +L+   I +AK    
Sbjct: 101 ILPNWETMWCSKK--VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICIARAKERWR 158

Query: 231 ----------------SACEK-----VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAY 269
                           SA ++     +I+ DI+RT+P   FF++  G   + L +++ AY
Sbjct: 159 SLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCFFQQ-GGPYHDMLHSILGAY 217

Query: 270 SLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQL 329
           + +  +VGY QG  FI  +L++ +   +AF     ++ +      F+     +       
Sbjct: 218 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAF 277

Query: 330 ENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFK 389
           E   +E LP L  HF+  + +  +Y                LACRI DVF  +G E +F+
Sbjct: 278 EVFFEENLPKLFAHFKKNNLTADIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFR 337

Query: 390 VALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQ 426
            AL +L L ++ L  +D     +++ + LP    AD+
Sbjct: 338 TALGILKLFEDILTRMDFIHSAQFLTR-LPEDLPADE 373


>UniRef50_Q4RGZ6 Cluster: Chromosome undetermined SCAF15081, whole
           genome shotgun sequence; n=4; Deuterostomia|Rep:
           Chromosome undetermined SCAF15081, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 883

 Score = 98.3 bits (234), Expect = 8e-19
 Identities = 60/194 (30%), Positives = 97/194 (50%), Gaps = 3/194 (1%)

Query: 224 ASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
           A+ +  + +   +I+ DI+RT+P    F +K G   + L +V+ AY+ +  ++GY QG  
Sbjct: 662 AASVADRESSLDLIKLDISRTFPSLFIF-QKGGPYHDLLHSVLGAYTCYRPDIGYVQGMS 720

Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMF-QLENLVQELLPDLHV 342
           FI  +L++ + E EAF     ++ +      F+    EL L  F   E   QE LP L  
Sbjct: 721 FIAAVLILNLEEAEAFITFANLLNKPCQMAFFRVDH-ELMLKYFGAFEIFFQENLPQLFS 779

Query: 343 HFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
           HFQS S +  LY                +ACR+ DVF  +G E +F+ AL +L L +  L
Sbjct: 780 HFQSNSLTPDLYLIDWIFTLYSKSLPLDVACRVWDVFCRDGEESLFRTALGILRLFEEVL 839

Query: 403 LSLDMESILKYIQK 416
           L +D   I +++ +
Sbjct: 840 LQMDFIHIAQFLSR 853


>UniRef50_Q23MA0 Cluster: TBC domain containing protein; n=2;
           Alveolata|Rep: TBC domain containing protein -
           Tetrahymena thermophila SB210
          Length = 2075

 Score = 98.3 bits (234), Expect = 8e-19
 Identities = 54/194 (27%), Positives = 100/194 (51%), Gaps = 3/194 (1%)

Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
           + K K+  E+VI+ D+ RT+ + +FFK      +  L  ++KA S  + ++GY QG  +I
Sbjct: 209 FSKLKNEYEEVIQNDVERTFQDQEFFKSVRN--KICLNQILKAISSSNSQLGYIQGINYI 266

Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
             +LL  MP EE + V  +I++++ +  +F      L L  FQ     +  +PDL  H +
Sbjct: 267 AAILLSIMPPEETYWVTKQILEKYNLASLFLDQFQNLELFTFQASCFFKNFIPDLFNHMK 326

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
             S    +                 L  +I+++F+ +G +I+ K  +ALL++ K ++L L
Sbjct: 327 IFSVQYEITIQRWVLSFFANDLDVQLMIKILNLFIFKGFKIIIKAVIALLSVHKKNILQL 386

Query: 406 -DMESILKYIQKEL 418
              E I +Y+Q+++
Sbjct: 387 KSQEEIYEYLQEKI 400


>UniRef50_UPI0000E46298 Cluster: PREDICTED: similar to mKIAA4104
           protein; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to mKIAA4104 protein -
           Strongylocentrotus purpuratus
          Length = 752

 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 50/130 (38%), Positives = 77/130 (59%), Gaps = 3/130 (2%)

Query: 162 GTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK- 220
           G + EE +   WG L++ W        + ++  VR+ VP   RG +WQLLAGV  S    
Sbjct: 562 GKDCEESILLGWGELLAKWRVNLSVHPKQLKGYVRKSVPEALRGEIWQLLAGVHESENLL 621

Query: 221 KLYASYIKAKSACEKVIRRDIARTYPEHD-FFKEKDGLGQESLFNVMKAYSLHDREVGYC 279
           + Y   I  +S  E+VI RDI+RT+  H+ F+ E +G GQ++++ + KAYS++D +VGY 
Sbjct: 622 EDYRILITKESPAEQVILRDISRTFTAHEKFYNENEG-GQDAMYKISKAYSVYDNDVGYT 680

Query: 280 QGSGFIVGLL 289
           QG  F+  +L
Sbjct: 681 QGLSFLAAVL 690


>UniRef50_A7AQU6 Cluster: RabGAP/TBC domain-containing protein,
           putative; n=4; Piroplasmida|Rep: RabGAP/TBC
           domain-containing protein, putative - Babesia bovis
          Length = 385

 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 72/262 (27%), Positives = 118/262 (45%), Gaps = 20/262 (7%)

Query: 175 RLVSNWESEWKRRNQW--------VRDLVRQGVPHHFRGIVWQLLAGVDT--SPEKKLYA 224
           R +  WE+  K +N+W        ++ L+R+G+P  +R  +W  L+G D   +    LY 
Sbjct: 80  RRLKRWEN-MKSKNEWTTSTNPFALKVLIRKGIPDEYRAKMWFQLSGADQLGAQISDLYP 138

Query: 225 SYIKAKSACE--KVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGS 282
             +    A E  + I  DI RT+P H  +K +   G +SL NV+ A++      GY Q  
Sbjct: 139 RLVSQPLAPEIAQQIEMDIYRTFPTHRNYK-RHSAGTQSLKNVLTAFANFVPSAGYTQSF 197

Query: 283 GFIVGLLLMQMPEEEAFAVLVKIMQQH------RMRDMFKPSMAELGLCMFQLENLVQEL 336
            F+  + L+ M EE+AF  LV+++          +   +K  M  L   +  LE L+Q+ 
Sbjct: 198 NFLAAIFLVFMEEEQAFLTLVQMIDSRISGKGLNVLGYYKDGMLALKRDVLVLEMLLQQR 257

Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
           L  L+ H ++     +                 P   RI DV   EG +++F+V  AL  
Sbjct: 258 LKKLYNHLKANGVDFTCVCAEWLLCHFSISLPIPTVLRIWDVLFHEGEKVLFRVCFALFK 317

Query: 397 LGKNDLLSLDMESILKYIQKEL 418
           + +  LL L M+  L    K +
Sbjct: 318 VHEKQLLRLTMDQDLLMYMKSM 339


>UniRef50_Q04322 Cluster: Uncharacterized protein YMR192W; n=2;
           Saccharomyces cerevisiae|Rep: Uncharacterized protein
           YMR192W - Saccharomyces cerevisiae (Baker's yeast)
          Length = 720

 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 73/328 (22%), Positives = 149/328 (45%), Gaps = 22/328 (6%)

Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASY 226
           E++ S W +++ ++++      + +   + +G+P  +R +VWQL++   +     +Y +Y
Sbjct: 266 EEVSSFWLKVIGDYQNILINDIETLHFQLSRGIPAAYRLVVWQLVSYAKSKSFDPIYETY 325

Query: 227 IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
           +   +        D+     +     E      + + NV+KAY L D E  +     +I+
Sbjct: 326 LTEMAPF------DVQEFENQLKMMDEVPSEYVKRISNVLKAYLLFDPECEFSTDIAYII 379

Query: 287 GLLLMQMPEE-EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
            ++L    EE  AF +LV++M+ + +R +F PS +E+ +  ++ + LV+E  P++H H  
Sbjct: 380 NMILDVCEEEANAFGLLVRLMKVYGLRLLFLPSASEIDILCYKFDRLVEEFYPEIHNHMV 439

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            +   +S++                +  RI D+   EGI+ + ++   LL+  ++ LL +
Sbjct: 440 EKGVRSSMFLPGFFTTLFQKKLPTEIQPRIGDMVFLEGIDSIMRILATLLSNSRDHLLKM 499

Query: 406 ---DMESILK------YIQK------ELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
              DM  +LK      YI++      +  L  E       +    V + PK MKK   EY
Sbjct: 500 GFDDMLELLKSGLLDAYIKQNDGTRGDTLLSNECMDKLLQDSMMKVAITPKTMKKYSSEY 559

Query: 451 TVIKTKEQGDIAVLRCLRQENRLLKQRV 478
             I   +       + + ++N  L++ V
Sbjct: 560 EEIHRLDNEKEVQYKSITEKNLHLQKHV 587


>UniRef50_Q96HU1 Cluster: RUN and TBC1 domain containing 3; n=34;
           Eumetazoa|Rep: RUN and TBC1 domain containing 3 - Homo
           sapiens (Human)
          Length = 749

 Score = 96.7 bits (230), Expect = 2e-18
 Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
           R++ +R LV  G+PH  R  +W  L+G +      +L Y   +K  S  E    K I +D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
           + RT P +  F     +G   L  V++A +    E+GYCQG+G +   LL+ + EE+AF 
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           ++  I++       F  ++  +      L +L+ + LP L    Q      SL       
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
                     L  RI D+F  EG  ++F++ L +L L + +L+  +  + +     ++P 
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 342

Query: 421 KAE 423
           + E
Sbjct: 343 QME 345


>UniRef50_Q7Z709 Cluster: RUN and TBC1 domain-containing protein 3;
           n=11; Tetrapoda|Rep: RUN and TBC1 domain-containing
           protein 3 - Homo sapiens (Human)
          Length = 777

 Score = 96.7 bits (230), Expect = 2e-18
 Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
           R++ +R LV  G+PH  R  +W  L+G +      +L Y   +K  S  E    K I +D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
           + RT P +  F     +G   L  V++A +    E+GYCQG+G +   LL+ + EE+AF 
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           ++  I++       F  ++  +      L +L+ + LP L    Q      SL       
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
                     L  RI D+F  EG  ++F++ L +L L + +L+  +  + +     ++P 
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 342

Query: 421 KAE 423
           + E
Sbjct: 343 QME 345


>UniRef50_Q9P2M4 Cluster: TBC1 domain family member 14; n=29;
           Coelomata|Rep: TBC1 domain family member 14 - Homo
           sapiens (Human)
          Length = 678

 Score = 96.7 bits (230), Expect = 2e-18
 Identities = 73/273 (26%), Positives = 122/273 (44%), Gaps = 32/273 (11%)

Query: 176 LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLY------------ 223
           ++ NWE+ W  R   VRDL  QG+P   RG VW L  G + +   +L+            
Sbjct: 366 ILPNWETMWCSRK--VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWR 423

Query: 224 -------------ASYIKA-KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAY 269
                        A +  A + A  ++I+ DI+RT+P    F++  G   + L +++ AY
Sbjct: 424 SLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ-GGPYHDMLHSILGAY 482

Query: 270 SLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQL 329
           + +  +VGY QG  FI  +L++ +   +AF     ++ +      F+     +       
Sbjct: 483 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAF 542

Query: 330 ENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFK 389
           E   +E LP L  HF+  + +  +Y                LACRI DVF  +G E +F+
Sbjct: 543 EVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFR 602

Query: 390 VALALLTLGKNDLLSLD---MESILKYIQKELP 419
            AL +L L ++ L  +D   M   L  + ++LP
Sbjct: 603 TALGILKLFEDILTKMDFIHMAQFLTRLPEDLP 635


>UniRef50_Q1H5B2 Cluster: At3g07890; n=7; Magnoliophyta|Rep:
           At3g07890 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 400

 Score = 96.3 bits (229), Expect = 3e-18
 Identities = 64/236 (27%), Positives = 112/236 (47%), Gaps = 13/236 (5%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAGV----DTSPEKKLYASYIKAKSA----CEKVIRRDIA 242
           ++ L+R+G+P   R  VW  L+G      T PE   Y+   KA         + I  D+ 
Sbjct: 109 LKRLIRKGIPPVLRPKVWFSLSGAAKKKSTVPES-YYSDLTKAVEGMVTPATRQIDHDLP 167

Query: 243 RTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQM-PEEEAFAV 301
           RT+P H +    +G    +L  V+  YS  D +VGYCQG  ++  LLL+ M  EE+AF +
Sbjct: 168 RTFPGHPWLDTPEG--HAALRRVLVGYSFRDSDVGYCQGLNYVAALLLLVMKTEEDAFWM 225

Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
           L  +++   +RD +  +++   +     ++L+ +    +  H +   F  SL A      
Sbjct: 226 LAVLLENVLVRDCYTTNLSGCHVEQRVFKDLLAQKCSRIATHLEDMGFDVSLVATEWFLC 285

Query: 362 XXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL-SLDMESILKYIQK 416
                       R+ DV   EG +++F  ALA+  + +N+LL +  +  ++  +QK
Sbjct: 286 LFSKSLPSETTLRVWDVLFYEGAKVLFHAALAIFKMKENELLMTHQVGDVINILQK 341


>UniRef50_Q9VP46 Cluster: CG7324-PA; n=3; Diptera|Rep: CG7324-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 1291

 Score = 96.3 bits (229), Expect = 3e-18
 Identities = 63/221 (28%), Positives = 108/221 (48%), Gaps = 13/221 (5%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAKSACEK------VIRRDIA 242
           V +L+ +G+P   R  +W + +G   D      LY   ++ K+AC K       I RD+ 
Sbjct: 455 VINLIVEGIPDKLRQEIWLIFSGAIHDKEMNPGLYEDLVE-KAACIKNCFAHDEIDRDLP 513

Query: 243 RTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVL 302
           R+ PEH  F+  DG+G  +L  V++AY+L + +VGYCQ    +  + L+   EE AF +L
Sbjct: 514 RSLPEHPAFQSTDGIG--ALRRVLQAYALRNPQVGYCQAMNIVSSVFLLFCDEENAFWML 571

Query: 303 VKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXX 362
             +  ++ + D +K  +    +    L  LV+  LPDLH H + Q     + +       
Sbjct: 572 ASLC-ENLLPDYYKDKVVGAQIDQGVLNELVETHLPDLHGHLE-QLGVIKMISISWFLTI 629

Query: 363 XXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
                    +  I+D F  EG +I+F ++L ++   ++ LL
Sbjct: 630 FMSVISYESSLHILDCFFYEGAKIIFMISLQIIEWNRDKLL 670


>UniRef50_Q553U1 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1223

 Score = 95.9 bits (228), Expect = 4e-18
 Identities = 65/242 (26%), Positives = 121/242 (50%), Gaps = 13/242 (5%)

Query: 191 VRDLVRQG-VPHHFRGIVWQLLAGVDT-----SPE--KKLYASYIKAKSACEKVIRRDIA 242
           ++ L+R G VP   R  +W L +G        SP+  + L  ++    ++    I +DI 
Sbjct: 746 LKSLIRNGGVPDVLRRKIWFLTSGAFYKSCCHSPDYYRSLIQTHQGDSNSSYVDIEKDIH 805

Query: 243 RTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVL 302
           R++P+H +F+EK+  GQ++L N+++AYS  +  +GYCQ    +  +LL+ + EEE F +L
Sbjct: 806 RSFPKHPWFREKEAGGQDALKNILQAYSWRNPSIGYCQSMNIVAAVLLIYLQEEEVFWLL 865

Query: 303 VKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXX 362
             + +   + D ++P M          ENL+ + LP +  H +  +   S+         
Sbjct: 866 CTLCED-LVPDYYRPGMVGSIADQKTFENLLAQYLPQVDQHLKRINCPLSMLILPRFLCL 924

Query: 363 XXXXXXXPLACRIMDVFLSEGI-EIVFKVALALLTLGKNDLLS--LDMESILKYIQKELP 419
                   L+ RI+D    EG  EI+FK+ L+   + + ++L      E I+ +++ + P
Sbjct: 925 FIGYAEMELSLRILDCLFFEGTSEILFKILLSFFKVNEYEILQNCKSTEDIMSFMRIQ-P 983

Query: 420 LK 421
           +K
Sbjct: 984 VK 985


>UniRef50_Q54H32 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 541

 Score = 95.9 bits (228), Expect = 4e-18
 Identities = 65/258 (25%), Positives = 126/258 (48%), Gaps = 20/258 (7%)

Query: 199 VPHHFRGIVWQLLAGV----DTSPEKKLYASYIKAKSA-CEKVIRRDIARTYPEHDF--- 250
           +P  +R  +W L+  +    D    K +Y   ++ K+   E  +R D  RT+P   +   
Sbjct: 155 LPDEYRTRIWALMEDLEKLKDNENNKNVYQQCLETKNEDIENDVRTDAVRTFPSSQYKVK 214

Query: 251 FKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHR 310
            K+K    +ESL+ V+KAY++++ EV Y QG  ++  +LL    EEE+F ++  ++++H 
Sbjct: 215 MKDKQSQNKESLYKVLKAYAIYNEEVQYTQGMNYLCLVLLCYFHEEESFWMMDLLIKKHG 274

Query: 311 MRDMF-KPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXX 369
           MR  F K S     L +F+LE  +++ LP+L  H + +     ++               
Sbjct: 275 MRHFFKKKSFLPSYLTIFELE--LEKHLPNLSKHLKDEGIQMYMFIQGWWSTIFVYVLPV 332

Query: 370 PLACRIMDVFL------SEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
                I D F          IE++F++++ALL + +++LL + M    + +++      +
Sbjct: 333 ETISTIWDYFFWGANGNGNSIEVLFRLSIALLKMLQSELLKVGMTEFFETLKEH---STK 389

Query: 424 ADQAAFMNLAYSVKVNPK 441
            D    +  AYS++++ K
Sbjct: 390 IDSLELVYQAYSIRLSIK 407


>UniRef50_UPI00004286DB Cluster: growth hormone regulated TBC
           protein 1; n=2; Homo/Pan/Gorilla group|Rep: growth
           hormone regulated TBC protein 1 - Homo sapiens
          Length = 354

 Score = 95.5 bits (227), Expect = 6e-18
 Identities = 67/215 (31%), Positives = 106/215 (49%), Gaps = 7/215 (3%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAKS--ACEKVIRRDIA 242
           R++ V+  VR+GVP   R  VW +L+G     ++    Y   ++ +     E  IR D+ 
Sbjct: 75  RSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLN 134

Query: 243 RTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQMPEEEAFA 300
           RT+P++  F K  D   Q +L+NV+ AY  H++ VGYCQG  FI G L+L+   EEE+F 
Sbjct: 135 RTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFW 194

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           +L  ++ +  + D + P+M  L      L  LV+  LP +    +      +L       
Sbjct: 195 LLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFI 253

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
                        RI D   +EG +I+F+VAL L+
Sbjct: 254 CLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 288


>UniRef50_Q9VEY4 Cluster: CG5916-PA; n=5; Endopterygota|Rep:
           CG5916-PA - Drosophila melanogaster (Fruit fly)
          Length = 330

 Score = 95.5 bits (227), Expect = 6e-18
 Identities = 64/261 (24%), Positives = 126/261 (48%), Gaps = 11/261 (4%)

Query: 195 VRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAKSACEKV---IRRDIARTYPEHD 249
           +R+G+P  +R  VW  ++G   +  +   L+ + ++ +   +++   I  D+ RT+P++ 
Sbjct: 67  IRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLPRTFPDNI 126

Query: 250 FFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQH 309
            F  K    ++ L+N++ AY+ H+R+VGYCQG  +I GLLL+   +EE    L+K + ++
Sbjct: 127 HFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVEN 182

Query: 310 RMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXX 369
            +      +MA L   +     LV   +P ++ H  +      + A              
Sbjct: 183 IVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPV 242

Query: 370 PLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE--ADQA 427
               RI D   +EG +IVF+ AL +    KN +L  D  + L  + ++  ++     D  
Sbjct: 243 ETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDNIVTDCH 302

Query: 428 AFMNLAYSVKVNPKKMKKLEK 448
            F+   +S+++   +++ L K
Sbjct: 303 GFVEAMFSLRLKRSELESLRK 323


>UniRef50_Q5TC63 Cluster: Growth hormone-regulated TBC protein 1;
           n=23; Eukaryota|Rep: Growth hormone-regulated TBC
           protein 1 - Homo sapiens (Human)
          Length = 336

 Score = 95.5 bits (227), Expect = 6e-18
 Identities = 67/215 (31%), Positives = 106/215 (49%), Gaps = 7/215 (3%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAKS--ACEKVIRRDIA 242
           R++ V+  VR+GVP   R  VW +L+G     ++    Y   ++ +     E  IR D+ 
Sbjct: 57  RSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLN 116

Query: 243 RTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQMPEEEAFA 300
           RT+P++  F K  D   Q +L+NV+ AY  H++ VGYCQG  FI G L+L+   EEE+F 
Sbjct: 117 RTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFW 176

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           +L  ++ +  + D + P+M  L      L  LV+  LP +    +      +L       
Sbjct: 177 LLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFI 235

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
                        RI D   +EG +I+F+VAL L+
Sbjct: 236 CLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 270


>UniRef50_A7ARE0 Cluster: GTPase activator protein, putative; n=1;
           Babesia bovis|Rep: GTPase activator protein, putative -
           Babesia bovis
          Length = 376

 Score = 95.1 bits (226), Expect = 8e-18
 Identities = 68/253 (26%), Positives = 118/253 (46%), Gaps = 13/253 (5%)

Query: 167 EDLW-SLWGRLVSNW-ESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD--TSPEKKL 222
           E+ W S+  R +S++ ++ W   N +VR   R G+P  FR   W++    D   +     
Sbjct: 35  EEKWVSMMKRGLSSFAKAHW---NTFVRRTNR-GIPQKFRWESWKVAMKFDENVATASPD 90

Query: 223 YASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGS 282
           Y ++    +    +I+ D+ RT+PE   F   D   Q+ L  ++ AYS +  EVGYCQG 
Sbjct: 91  YHTFASQPNEYMSIIQIDVPRTFPELQVF---DTEAQQQLSRILLAYSNYHPEVGYCQGM 147

Query: 283 GFIVGLLLM--QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDL 340
            FI G++L+     E E++   V +M++  + + +KPS   +   +   + L  E+ PDL
Sbjct: 148 NFIAGMILLVSGFNEMESYVGFVGLMKELGLAEFYKPSFPLIQKYIRAFDALTAEMWPDL 207

Query: 341 HVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKN 400
           H HF+ +  S +++                    + D  L  G+  +  VAL L  L   
Sbjct: 208 HRHFEREEISVAVFLNQWFLTMFVIILPLRTVIALWDYILFNGLSSILSVALGLQYLLAP 267

Query: 401 DLLSLDMESILKY 413
            +  L  E+I+ +
Sbjct: 268 QMKQLKFEAIMTF 280


>UniRef50_Q2H4R6 Cluster: Putative uncharacterized protein; n=3;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Chaetomium globosum (Soil fungus)
          Length = 1240

 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 69/239 (28%), Positives = 114/239 (47%), Gaps = 10/239 (4%)

Query: 172 LWGR-LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKK-LYASYIK 228
           LW   L  N  +    R      L+R G+P+  RG +W+L +G +    E   LYA  + 
Sbjct: 302 LWAEYLRDNGRNTTLIRQPTFHKLIRVGLPNRLRGEMWELTSGSIYLRLESPTLYADTLA 361

Query: 229 AKSACEKV----IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
             S  E +    I +D+ R+ PE+  F+ ++G+G+  L  V+ AYS  + +VGYCQ    
Sbjct: 362 KFSGQESLAIDEIEKDLNRSLPEYPGFQSEEGIGR--LRRVLTAYSWVNADVGYCQAMNI 419

Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
           +V  LL+ M E +AF  L+  +    +   +  +M    L     E+LV++ +P L  H 
Sbjct: 420 VVAALLIYMSEAQAF-FLLSALCDRLVPGYYSTTMYGTLLDQKVFESLVEKTMPILWEHL 478

Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
                  S+ +                A R++DVF  EG +++F+V LA+L +   +LL
Sbjct: 479 VKSDVQLSVVSLPWFLSLYINSMPLVFAFRVLDVFFVEGPKVLFQVGLAILRINGEELL 537


>UniRef50_UPI000051A1A7 Cluster: PREDICTED: similar to TBC1 domain
           family, member 14; n=1; Apis mellifera|Rep: PREDICTED:
           similar to TBC1 domain family, member 14 - Apis
           mellifera
          Length = 620

 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 68/241 (28%), Positives = 112/241 (46%), Gaps = 9/241 (3%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAK-----SACEKVIRRDIARTY 245
           VR+L  +G+P   RG VW+L    + +    LY   ++       S     I+ D+ RT+
Sbjct: 355 VRELWWRGLPPSVRGKVWKLAIPNNLNITTHLYNICLERAISSPISETLAAIKLDVFRTF 414

Query: 246 PEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKI 305
           P    F+E   L   SL  ++ AY+++  +VGY QG  F+  +L + M   +AF     +
Sbjct: 415 PTLCVFQEGGPLSN-SLQGILAAYAVYRPDVGYVQGMSFVGAVLSLNMEAPDAFTCFANL 473

Query: 306 MQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXX 365
           +     R  F  +  ++ +      + +   LP +  HF     S  LY           
Sbjct: 474 LNHPCHRAAFTLNQKQMDIYYKVYSSALAHKLPKIFSHFTVAGLSPDLYLLDWLYTIYAK 533

Query: 366 XXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELP--LKAE 423
                +ACRI DVFL +G E +F+ AL +L L + +LL +D     +++ + LP  L+AE
Sbjct: 534 AMPLDVACRIWDVFLRDGDEFLFRTALGVLHLYQEELLKMDFVHGAQFLTR-LPETLQAE 592

Query: 424 A 424
           A
Sbjct: 593 A 593


>UniRef50_Q7RB90 Cluster: Plant adhesion molecule 1; n=4;
           Plasmodium|Rep: Plant adhesion molecule 1 - Plasmodium
           yoelii yoelii
          Length = 376

 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 50/217 (23%), Positives = 104/217 (47%), Gaps = 2/217 (0%)

Query: 204 RGIVWQ-LLAGVDTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESL 262
           R  +W+ +L   +    +  Y  Y K KS  + +I +DI RT+P + +F  +    Q  L
Sbjct: 160 RKFIWKAILLAENIYMNENQYNEYQKKKSCYDNIIEKDINRTFPNNPYFINRKEDMQNKL 219

Query: 263 FNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE-EAFAVLVKIMQQHRMRDMFKPSMAE 321
            N++K  SL+ +++GYCQG  ++  +LL+      +A    + +++   ++ MF     +
Sbjct: 220 SNILKICSLYFKDIGYCQGMNYVAAILLLVFQNNLDAIRCFIALLKGFNLKGMFIYKFPQ 279

Query: 322 LGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLS 381
           L   ++QL  L++  +P L  +F+ +      +                   ++ D+F  
Sbjct: 280 LKKIIYQLNILIKAYMPKLFYYFKRKKIKIDFFCINWFMTLFSQDLSFENTLKLWDMFFL 339

Query: 382 EGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKEL 418
            GI+I+ K +LA+L   +  +L++  +  L ++ + L
Sbjct: 340 FGIKILIKFSLAILYHHQQKILTMSYDQALIFLNQLL 376


>UniRef50_Q54Z16 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1047

 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 58/228 (25%), Positives = 107/228 (46%), Gaps = 7/228 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA--- 229
           W  +V+NW      + + +  L  +G+P++ R +VW+ +  ++   + + + +Y K    
Sbjct: 108 WIHIVNNWNDYLINQPEKLLYLSSKGIPNNLRPLVWRKMLNINYF-KNQYHENYFKELCN 166

Query: 230 KSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
           K + E    I  DI RT+P H  F  + G  +  L +V+++YS H+  VGYCQG  +I G
Sbjct: 167 KPSNEHTEQIELDIPRTFPNHKRFFTQRGYVKNDLLDVLQSYSYHNPNVGYCQGMSYIAG 226

Query: 288 LLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQ 347
           +LLM +  E+ F + V ++++  M   + P M +L       + +++     L  H    
Sbjct: 227 VLLMFLSPEDTFWLFVSLLERETM-GYYIPGMPQLIFDSILFQKILEIENKPLGQHLLKN 285

Query: 348 SFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
                LY                   R+ D+ L EG+  +F+ +L +L
Sbjct: 286 GIDPLLYVTPWWMCFFTTLPDWGTVLRLWDLILLEGVNSLFRFSLVIL 333


>UniRef50_Q5KAJ1 Cluster: Mic1-like protein, putative; n=1;
           Filobasidiella neoformans|Rep: Mic1-like protein,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 1053

 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 63/218 (28%), Positives = 112/218 (51%), Gaps = 9/218 (4%)

Query: 194 LVRQGVPHHFRGIVWQLLAGVD----TSPEK-KLYASYIKAK-SACEKVIRRDIARTYPE 247
           L++ G+P   RG +W++++G      ++P+   L  S    K S     I +D+ R+ PE
Sbjct: 270 LLQVGLPSRLRGELWEVMSGSIYLRFSNPQTYDLLLSQNAGKHSQSTDEIEKDLNRSLPE 329

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
           +  ++ ++GL +  L  V+ AYS  + E+GYCQ    +V  LL+ M E++AF  L++++ 
Sbjct: 330 YKAYQSEEGLAR--LRRVLVAYSFRNPELGYCQALNIVVAGLLIYMSEQQAF-WLLEVLC 386

Query: 308 QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
              +   + PSM    L     E+LV   LP +H HF+S     S+ +            
Sbjct: 387 DRILPGYYSPSMEGTLLDQRVFESLVHRCLPMIHEHFKSVDVQISVASLPWFLSLYINSM 446

Query: 368 XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
               A RI+D  L+ G++++F++ LA+L +    LL +
Sbjct: 447 PLIFAFRIVDCVLAMGVKVLFQIGLAVLKINGEALLQV 484


>UniRef50_Q9Z1A9 Cluster: TBC1 domain family member 8; n=22;
           Amniota|Rep: TBC1 domain family member 8 - Mus musculus
           (Mouse)
          Length = 891

 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 66/241 (27%), Positives = 111/241 (46%), Gaps = 11/241 (4%)

Query: 171 SLWG-RLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLL--AGVDTSPEKKLYASYI 227
           SLW    V    +    R + +R LV  G+P   RG +W L   A  D +     Y + +
Sbjct: 233 SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLV 292

Query: 228 KAK--SAC--EKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
           +      C   + I RD+ R+ PEH  F+ + G+   +L  V+ AY+  + ++GYCQ   
Sbjct: 293 EQSLGRCCLVTEEIERDLHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMN 350

Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
            +  +LL+   EEEAF +LV + ++  + D F   +    +     E L++E LP+L  H
Sbjct: 351 ILTSVLLLYAKEEEAFWLLVAVCER-MLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEH 409

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
               S   S+ +                A  ++D F  +GI+ +F++ LA+L     +L 
Sbjct: 410 MSDLSALASI-SLSWFLTLFLSIMPLESAVHVVDCFFYDGIKAIFQLGLAVLEANAEELC 468

Query: 404 S 404
           S
Sbjct: 469 S 469


>UniRef50_A0DWA3 Cluster: Chromosome undetermined scaffold_67, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_67,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 388

 Score = 93.1 bits (221), Expect = 3e-17
 Identities = 76/302 (25%), Positives = 145/302 (48%), Gaps = 29/302 (9%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-------DTSPEKKLYAS 225
           W ++++ ++   K+  Q +++  R+G+P   R + W LLA +       +T  +   Y+ 
Sbjct: 87  WRQMINEFD---KQNIQLIKERTRKGIPDGLRILAWPLLANIKKAKETANTIQKTSKYSD 143

Query: 226 YI-KAKSACEKVIRRDIARTYPEHDFFK------EKDGLGQESLFNVMKAYSLHDREVGY 278
           ++ K +   E  IR D+ RT+P++  F+      +   +  ESL NV+KA S    ++GY
Sbjct: 144 FLTKNEFKFEHQIRLDVHRTFPDNINFQVSILQIQDQTVLSESLVNVLKALSEAIPDMGY 203

Query: 279 CQGSGFIVGLLLMQMPEE--------EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLE 330
           CQG  F+   L+M   +E        EAF +L ++M  + +   +K   + L    + L+
Sbjct: 204 CQGLNFLTAALIMVTNDENVRILNNFEAFWILYRLMTHYNLTAKYKDPNS-LYREFYILD 262

Query: 331 NLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKV 390
           NL+Q+  P      +  +     +                L  R+ ++FL EG + +F+ 
Sbjct: 263 NLIQQYHPITSKILKRHNIDLFYFTTEWFITLFSTALPINLFYRVFEIFLVEGEKTIFRC 322

Query: 391 ALALLTLGKNDLLSL-DMESILKYIQKELPLKAEADQAAFMNLAYS-VKVNPKKMKKLEK 448
           ALA++   +  L+ L D E+ L+Y++    L    D   F+NL  S  K +   +++L++
Sbjct: 323 ALAIIHYKEQKLIQLNDFENGLQYLRSNEDL-LHLDSNQFINLMLSKYKFSKTTIQQLDQ 381

Query: 449 EY 450
           +Y
Sbjct: 382 KY 383


>UniRef50_P53258 Cluster: GTPase-activating protein GYP2; n=5;
           Saccharomycetales|Rep: GTPase-activating protein GYP2 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 950

 Score = 93.1 bits (221), Expect = 3e-17
 Identities = 68/247 (27%), Positives = 118/247 (47%), Gaps = 15/247 (6%)

Query: 192 RDLVRQGVPHHFRGIVWQLLAGV-------DTSPEKKLYASYIKAKSACEKVIRRDIART 244
           R L+R GVP+  RG +W+L +G            E+ L  +  K   A ++ I +D+ R+
Sbjct: 238 RKLIRIGVPNRMRGEIWELCSGAMYMRYANSGEYERILNENAGKTSQAIDE-IEKDLKRS 296

Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVK 304
            PE+  ++ ++G+  + L NV+ AYS  + +VGYCQ    +V   L+ M EE+AF  L  
Sbjct: 297 LPEYSAYQTEEGI--QRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEEQAFWCLCN 354

Query: 305 IMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXX 364
           +   + +   +  +M    L     E+ V++ +P L  +        S+ +         
Sbjct: 355 LCDIY-VPGYYSKTMYGTLLDQRVFESFVEDRMPVLWEYILQHDIQLSVVSLPWFLSLFF 413

Query: 365 XXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME----SILKYIQKELPL 420
                  A RIMD+F   G   +F+VALA+L +  +D+L  D +    +I+K+  + L  
Sbjct: 414 TSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINADDILQADDDGMFIAIIKHYFQTLGQ 473

Query: 421 KAEADQA 427
            A  D +
Sbjct: 474 SAHPDSS 480


>UniRef50_Q23419 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 908

 Score = 92.7 bits (220), Expect = 4e-17
 Identities = 64/221 (28%), Positives = 101/221 (45%), Gaps = 14/221 (6%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAG---VDTSPE--KKLYASYIK---------AKSACEKV 236
           ++ L+R GVP  +RG VW+++      D   E     Y S ++         +  A  K 
Sbjct: 623 LKTLIRTGVPPAYRGRVWKIIVTHWVKDKQAELGNGYYQSMLRKAGTKKQDGSYDAAIKQ 682

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
           I  D+ART P +  F E D    E L NV+ A+  H+  VGYCQG   +  + L+ + E+
Sbjct: 683 IDLDLARTLPTNKLFDEPDSANIEKLRNVLYAFRYHNSHVGYCQGLNRLAAIALLNLDEQ 742

Query: 297 EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAX 356
           ++F  LV  ++  +    +  S+         L +LV E LP L  H ++     SL+A 
Sbjct: 743 DSFWFLVACVEHLQPEGYYTSSLIGAVADQKVLRDLVAEKLPKLAAHLRALEVDLSLFAL 802

Query: 357 XXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTL 397
                         +   I D FL EG +++F+ ALAL  +
Sbjct: 803 SWFLTCFVDVLPHSIYLTIFDAFLYEGNKVLFRFALALFKI 843


>UniRef50_A2EQP1 Cluster: TBC domain containing protein; n=2;
           Trichomonas vaginalis G3|Rep: TBC domain containing
           protein - Trichomonas vaginalis G3
          Length = 323

 Score = 92.7 bits (220), Expect = 4e-17
 Identities = 78/315 (24%), Positives = 135/315 (42%), Gaps = 12/315 (3%)

Query: 164 NGEEDLWSL--WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPE 219
           N   DL  L  W  ++ NW++  K     +   +R GVP  +RG VW LL    V  S  
Sbjct: 4   NKSRDLTHLRDWKYIIQNWDTLMKESRSLIIRSLRLGVPTKYRGDVWALLTNQKVVKSKA 63

Query: 220 KKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYC 279
              Y    K  S    +I  D+ RT P   +  +     ++ L  ++ AY+  D E+GY 
Sbjct: 64  NFTYEQIDKVNSNSSHIISLDVPRTMPS--WTNDTSQKFRDELSRILNAYANVDPELGYT 121

Query: 280 QGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRM--RDMFKPSMAELGLCMFQLENLVQELL 337
           QG  FI  + L+  PEE+AF     +M Q  +  R  F     +L L    +  L+ E  
Sbjct: 122 QGMNFIASMFLIYQPEEQAFWSFYSLMFQSSLPHRLFFIQDFPKLNLLKALVTRLIHENF 181

Query: 338 PDLHVHFQSQSFSTSLYA-XXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
           PD++   + +    +L+                 L+  I + FL+ G+  +    L +L 
Sbjct: 182 PDIYEALEERRLDCTLFTPMWLMVCFLSGNFGLELSTFIFEQFLAFGVPPLLSFGLGILE 241

Query: 397 LGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAY-SVKVNPKKMKKLEKEYTVIKT 455
           + KN L     E +L  +          D+ A +N A+  + +  ++  +L KE  + + 
Sbjct: 242 IHKNVLKEKGFEDLLHVLTNPGSSPLMNDKQA-VNAAWDKMWITTRRYHQLLKE-IIEEE 299

Query: 456 KEQGDIAVLRCLRQE 470
           K++ D  +L+ + ++
Sbjct: 300 KKKDDSKLLKYIDKD 314


>UniRef50_Q7RRJ2 Cluster: Putative uncharacterized protein PY00727;
           n=5; Plasmodium|Rep: Putative uncharacterized protein
           PY00727 - Plasmodium yoelii yoelii
          Length = 391

 Score = 92.3 bits (219), Expect = 5e-17
 Identities = 69/281 (24%), Positives = 132/281 (46%), Gaps = 13/281 (4%)

Query: 186 RRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACEKV--IRRDI 241
           ++N +++ L+R+G+P  FR  +W  L G  V  +    +Y   + ++   + +  I  D+
Sbjct: 108 KKNYYLKKLIRKGIPDKFRMNIWPYLLGSVVLYTKYPTIYERCLNSEIEPKVLSQIELDM 167

Query: 242 ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
            RT+P H+   + +  G   L NV++A++++  ++ YCQ   FI  + L+ + EE AF  
Sbjct: 168 LRTFP-HNKNYQLNAQGLTKLRNVLRAFAIYKPKINYCQSMNFIAAITLLFLKEELAFWS 226

Query: 302 LVKIMQ---QHR---MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
           +V+++     H+   + D +   M  L   +  +E L++   P++++H +      S   
Sbjct: 227 IVQLIDSDYSHKKINISDYYNHEMRGLRRDIIVIEELIKIKFPNIYMHMKEFDVDVSWIC 286

Query: 356 XXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL-SLDMESILKYI 414
                             RI D    EG +I+F++ LAL  + +  L+ S  +ESIL   
Sbjct: 287 SEWLLCLFCTAFPITTTLRIWDCLFYEGDKILFRIVLALFKMNQEKLIKSNSLESILYLF 346

Query: 415 QKELPLKAEADQAAFMNLAYSVKVNPKKMKKLE-KEYTVIK 454
           ++      E+D+           +  KK+KKL  K   +IK
Sbjct: 347 KESTKNMVESDKLMHTAFKEIGSLKKKKIKKLRMKADDIIK 387


>UniRef50_Q4UCH6 Cluster: Putative uncharacterized protein; n=2;
           Theileria|Rep: Putative uncharacterized protein -
           Theileria annulata
          Length = 346

 Score = 92.3 bits (219), Expect = 5e-17
 Identities = 62/233 (26%), Positives = 103/233 (44%), Gaps = 17/233 (7%)

Query: 197 QGVPHHFRGIVWQLLAGVDT--SPEKKLYASYIKAKSACEKVIRRDIAR----------T 244
           +G+P  +R   W++    +   S    LY SY    +    +I  D+ R          T
Sbjct: 63  RGIPQRYRWESWKVALNYNHYFSIVGDLYESYSTKHNEYSSIINIDVPRLSNYSLISFRT 122

Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQ--MPEEEAFAVL 302
           +PE   F ++    Q  L  ++ AY  +  E+GYCQG  F+ GLLL+     E+EAF   
Sbjct: 123 FPELKVFNKES---QNQLHRILSAYGNYQPEIGYCQGMNFVAGLLLLVSGFNEKEAFVAF 179

Query: 303 VKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXX 362
           V +M + ++ + +KPS   + L     ENL++ L P L+ H + +  S S++        
Sbjct: 180 VGLMNEFKLLEFYKPSFPVIKLYTAGFENLLKRLSPQLYDHLKKEDVSVSVFLNQWFLTL 239

Query: 363 XXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQ 415
                       + D  L  G+  V  V+L L+ L    +  L+ E IL  ++
Sbjct: 240 FVASLPLRTVVALWDYMLYNGLSSVLTVSLGLMWLLMPQITRLNFEGILTLLK 292


>UniRef50_O95759 Cluster: TBC1 domain family member 8; n=45;
           Euteleostomi|Rep: TBC1 domain family member 8 - Homo
           sapiens (Human)
          Length = 897

 Score = 92.3 bits (219), Expect = 5e-17
 Identities = 68/243 (27%), Positives = 112/243 (46%), Gaps = 15/243 (6%)

Query: 171 SLWG-RLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLL--AGVDTSPEKKLYASYI 227
           SLW    V    +    R + +R LV  G+P   RG +W L   A  D +     Y + +
Sbjct: 234 SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLV 293

Query: 228 KAK--SAC--EKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
           +      C   + I RD+ R+ PEH  F+ + G+   +L  V+ AY+  + ++GYCQ   
Sbjct: 294 EESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMN 351

Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
            +  +LL+   EEEAF +LV + ++  + D F   +    +     E L++  LP+L  H
Sbjct: 352 ILTSVLLLYTKEEEAFWLLVAVCER-MLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEH 410

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPL--ACRIMDVFLSEGIEIVFKVALALLTLGKND 401
               S   +L +              PL  A  ++D F  +GI+ +F++ LA+L     D
Sbjct: 411 MNDLS---ALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAED 467

Query: 402 LLS 404
           L S
Sbjct: 468 LCS 470


>UniRef50_UPI000150A407 Cluster: TBC domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: TBC domain containing
           protein - Tetrahymena thermophila SB210
          Length = 389

 Score = 91.9 bits (218), Expect = 7e-17
 Identities = 71/269 (26%), Positives = 129/269 (47%), Gaps = 26/269 (9%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP-EKKL--YASYIKA 229
           W ++V     E + +NQ ++  + +G+P+  R  VW +L+ V+    + K+  Y    K 
Sbjct: 82  WKQIVVKKSLE-EFQNQRIQFSLLKGIPYDVRKDVWLILSKVEELKIQNKMFNYEVMSKT 140

Query: 230 KSACEKVIRRDIARTYPEHDFFK-----EKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
           +   +K+I +D+ RT+ +  FF+     +K   G+E LF V++AYS  D+E+GY QG  F
Sbjct: 141 EGPSDKLILKDLNRTFSDMRFFQIYDKHDKIYEGREKLFRVLRAYSHFDQEIGYTQGMNF 200

Query: 285 IVGLLLMQMP----------------EEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQ 328
           I   LL+ +                 EE  F +LV IM     R +F      +   +  
Sbjct: 201 IAASLLVHLNPDNEKDLEVEFINKEYEENTFWILVHIMHVKNWRILFLDGTPGIHQMIKT 260

Query: 329 LENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVF 388
           L+  ++E +P +  H       +                   +  RI+D+FL EG +I++
Sbjct: 261 LDQKMKEYVPQIFQHIADVGLDSYSCFSQYFFTILLYNAPKTVQKRILDLFLFEGEQILY 320

Query: 389 KVALALLTLGKNDLLSL-DMESILKYIQK 416
            V + +LTL  + +LS+ DM+ ++++ +K
Sbjct: 321 SVIIKMLTLCSDIILSIYDMQKMMEFFKK 349


>UniRef50_UPI00006CB764 Cluster: TBC domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: TBC domain containing
           protein - Tetrahymena thermophila SB210
          Length = 883

 Score = 91.9 bits (218), Expect = 7e-17
 Identities = 64/252 (25%), Positives = 126/252 (50%), Gaps = 12/252 (4%)

Query: 180 WESEWKRR--NQWVRDLVRQGV-PHHFRGIVWQLLAGVDT-----SPEKKLYASYIKAKS 231
           + S+ +RR  N+ ++ L+ +G+ P + R   W  ++  +      +PE   Y +    + 
Sbjct: 435 FRSKRQRRLINKQLKFLMIKGLLPKNMRAKYWVHISRANDFKKTFTPEN--YRTLSVCEP 492

Query: 232 ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM 291
            CE+ I +DI RT+P    FK K+   +  L  V++A S    ++ YCQG  ++VG LL+
Sbjct: 493 RCEREIVQDIDRTFPNIKEFKTKEKTFK--LQKVLRALSFCLPDMEYCQGLNYVVGSLLL 550

Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFST 351
              EEE+F + V +++ +  +D +   +  L   +  L+NL++   P +      ++  T
Sbjct: 551 YADEEESFYICVSMLKNYGFKDCYFEDLNGLQQAVKILDNLIKLYFPHVADFLNKKNIQT 610

Query: 352 SLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESIL 411
            L+A                  R++D+FL  G +I+F+++LA++   +  + + D + I+
Sbjct: 611 GLFATSWFNTLFAYDFPRQFFIRVIDLFLFSGWKILFQISLAIIQEAQFTIFTADEDDIV 670

Query: 412 KYIQKELPLKAE 423
             I+K L +  E
Sbjct: 671 NIIKKGLSMNQE 682


>UniRef50_UPI000049837E Cluster: Rab GTPase activating protein; n=1;
           Entamoeba histolytica HM-1:IMSS|Rep: Rab GTPase
           activating protein - Entamoeba histolytica HM-1:IMSS
          Length = 624

 Score = 91.5 bits (217), Expect = 9e-17
 Identities = 73/287 (25%), Positives = 135/287 (47%), Gaps = 25/287 (8%)

Query: 180 WE---SEWKRRNQWVRDL---VRQGVPHHFRGIVWQLLAGVDTSPEKKLYASY------I 227
           WE    EW +  +  R L   V + VP + R   W++   ++ S ++  Y  Y      +
Sbjct: 331 WEIMLDEWNKSGKVPRALFHRVYKFVPLNKRKKYWEIELKINQSIQE--YNGYFARITEL 388

Query: 228 KAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
             +   ++ I +D+ R +  +  F  K   GQ +LF V++A+S+ D ++GY QG   + G
Sbjct: 389 PERGKDDEQIHKDVMRAHQNNIHFMAKFNDGQRTLFRVLRAWSMQD-DLGYVQGMSDLCG 447

Query: 288 LLLMQMPEEE----AFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
            L++ + EEE     F+ L+    ++ +R+MF P    +  C F    ++++  P +  H
Sbjct: 448 FLILILQEEEEVYWGFSALMN-NPKYNLREMFLPGFPGINKCAFVAMKVMKKYHPKIFYH 506

Query: 344 FQSQSF---STSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKN 400
            +S+ +   +   Y                   RI+D+ L EG EIVF +  A+L   K 
Sbjct: 507 LKSKEYDFDNWKTYMLEYFMLWFCRCFHPEFEVRILDLILMEGWEIVFSIFSAILHYSKV 566

Query: 401 DLLSLDMESIL-KYIQKELPLK-AEADQAAFMNLAYSVKVNPKKMKK 445
           ++L +D    + K +   + L  ++ DQ  F+N     ++ PK++KK
Sbjct: 567 EILKMDEYIFIDKALADPMTLMGSQFDQDKFINFVKKARITPKEIKK 613


>UniRef50_Q54UM5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 717

 Score = 91.5 bits (217), Expect = 9e-17
 Identities = 66/295 (22%), Positives = 135/295 (45%), Gaps = 21/295 (7%)

Query: 167 EDLWSLWGR-LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYAS 225
           E+   +W   ++ NW+   ++  +  R++V QG+P   R  VW LL G D +   +L++ 
Sbjct: 426 EESLKIWNEDMIPNWDK--RKGTKKCREMVLQGIPSLVRSKVWPLLIGNDLNITPELFSI 483

Query: 226 Y-IKAKSACEK-------------VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSL 271
           +  +A+ A +K             +I  D+ RT+P    F+++  L Q SL NV++AY  
Sbjct: 484 FGARAERAKQKSEARSLGREKTVSLIHLDLPRTFPMLSIFQDEGPLHQ-SLANVLEAYVC 542

Query: 272 HDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN 331
           +  +VGY QG  ++  + L+ + E  +F  L   +        +  ++ ++ + M  ++ 
Sbjct: 543 YRPDVGYVQGMSYLAAVFLLILDEFNSFVCLSNFLNNPCYMTFYTMNLDQMAVYMNTMDQ 602

Query: 332 LVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVA 391
           L+ + LP +  H +       ++                +A  + D    +G  ++F+ A
Sbjct: 603 LMAQNLPKIQKHLKELGIQPDIFMIDWVLTVFSKALPLDVASHVWDTIFLDGEVVIFQTA 662

Query: 392 LALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
           L +L +   DL   D + +   +   LP   + D+  F ++  S ++N K + K+
Sbjct: 663 LGILKMYSKDLEFGDFD-VCMTLLTHLPTDIDEDE-LFQHI-NSFQINQKLLNKM 714


>UniRef50_UPI000065F402 Cluster: Homolog of Homo sapiens "TBC1
           domain family member 10A; n=1; Takifugu rubripes|Rep:
           Homolog of Homo sapiens "TBC1 domain family member 10A -
           Takifugu rubripes
          Length = 293

 Score = 91.1 bits (216), Expect = 1e-16
 Identities = 65/252 (25%), Positives = 110/252 (43%), Gaps = 31/252 (12%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDT--SPEKKLYASYIKAK 230
           W  ++  W+    +R   ++   ++G+P   R   W LL G        + LY   + ++
Sbjct: 10  WINIIVQWDQILLKRTNKIKVQCQKGIPASLRAKCWPLLCGAAARMKQNENLYQC-LDSQ 68

Query: 231 SACEK---VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
           SA +    VI RD+ R +P H+ F  KDG GQ  LF V+K+Y+ +  E GYCQ  G +  
Sbjct: 69  SALQSWVDVINRDLDRQFPFHEMFLSKDGHGQRGLFRVLKSYTQYKPEEGYCQAQGPVAA 128

Query: 288 LLLMQMPEE------------------------EAFAVLVKIMQQHRMRDMFKPSMAELG 323
           +LLM MP E                        EAF  LV+I +Q+ +   + P +  + 
Sbjct: 129 VLLMNMPAEVPKHAAETAFTVEPDSGLCFVTMQEAFWCLVQISEQY-LPGYYSPLLEGVL 187

Query: 324 LCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG 383
                L+ +++ + P  H H Q       ++A                  R+ D+F   G
Sbjct: 188 FDAALLDWVLKRICPAAHKHLQHHDVEPLMFATDWLMCLFTRHLPFNALLRVWDLFFCYG 247

Query: 384 IEIVFKVALALL 395
           + ++ +VA+ L+
Sbjct: 248 VRVLLQVAVVLV 259


>UniRef50_Q93316 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 1272

 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 62/275 (22%), Positives = 122/275 (44%), Gaps = 21/275 (7%)

Query: 194 LVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSAC---------------EKVIR 238
           + R+G+P+  R  VW++L        K +Y  Y   ++ C               +K I 
Sbjct: 371 MCRKGIPNSLRATVWKILINQQVEDLKNVYGKYYY-RNLCNIQGGEDEKTYSDVHQKQIN 429

Query: 239 RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEA 298
            D+ RT P +  F   +  G   L  V+ A+ LH+ ++GYCQG  F+    L+ +  E+A
Sbjct: 430 LDLLRTMPNNVHFMSANSKGVTQLLQVLHAFCLHNSQIGYCQGMNFLAATALLFVGPEDA 489

Query: 299 FAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXX 358
           F  L+ + +++  +  F  ++         L+ L++   P +  H +S     + +    
Sbjct: 490 FWFLIAVTERYFDKTYFDSNLTGAQADQEVLKGLLEVQHPKIMKHLKSLDIDVASFTLNW 549

Query: 359 XXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQKE 417
                          RI D FL EG +++F+ A+ L+   + +++S  D   I++    +
Sbjct: 550 FISLFFDAVPFNTLLRIWDCFLLEGPKVLFRFAIVLIGKHEEEIISRGDAIGIMRV--SK 607

Query: 418 LPLKAEADQAAFMNLAYSVKVNPKK--MKKLEKEY 450
              K   D+ A +N+A+ +   P +  +K ++ +Y
Sbjct: 608 AATKLAFDEEAIVNMAFRIPNLPTRIELKNMQLQY 642


>UniRef50_Q55E78 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 831

 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 48/182 (26%), Positives = 97/182 (53%), Gaps = 3/182 (1%)

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
           I +D+ RT+  H +F++ +G G +SL  ++ AYS  +  +GYCQG   + G++L+ M EE
Sbjct: 579 IEKDVRRTFSHHPYFRD-NGAGVDSLRRILIAYSRRNPTIGYCQGMNNVAGIMLLYMKEE 637

Query: 297 EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAX 356
            AF VL K+++ + + D +   M    +     E+L +E LP++  H +       + + 
Sbjct: 638 AAFWVLCKVVELY-LCDYYSKEMIGSIVDQNIFEDLCKEYLPEVFNHLERIGLPVKILST 696

Query: 357 XXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS-LDMESILKYIQ 415
                         +A R++D    +G  ++F+V LA+L + KN +++  + E +++ ++
Sbjct: 697 PWFICLFVSYIPFYVATRVIDCLFLDGTTVLFQVGLAILKINKNAIIAERESEVVIELVR 756

Query: 416 KE 417
            +
Sbjct: 757 NK 758


>UniRef50_A7REP1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1168

 Score = 89.8 bits (213), Expect = 3e-16
 Identities = 62/247 (25%), Positives = 113/247 (45%), Gaps = 12/247 (4%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LY 223
           +E LW L   L          R     +L+ +G+P + R  +W + +G     E     Y
Sbjct: 490 KEHLWRL--HLAEYGRGVCMYRTVKTHELILKGIPDNLRAEIWLIFSGAINEIETHPGYY 547

Query: 224 ASYIKA----KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYC 279
            S ++      S     I RD+ R+ PEH  F+   G+G  +L  V+ AY+  +  +GYC
Sbjct: 548 VSLVEQCEGKSSLAFDEIERDLHRSLPEHPAFQSDVGIG--ALRRVLTAYAWRNPSIGYC 605

Query: 280 QGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPD 339
           Q    +  +LL+   EE+AF +LV + ++  + D +   +    +     E+L ++ LP+
Sbjct: 606 QAMNIVASVLLLYCTEEQAFWLLVAVCER-LLPDYYNTKVVGALVDQGVFEDLTRDHLPE 664

Query: 340 LHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGK 399
           L+ H +      ++ +                A  I+D F  +G +++F++ALA L   +
Sbjct: 665 LYDHLKDLGI-LNMISLSWFLTLFLSVMPFVCAVNIIDCFFYDGAKVLFQIALACLDANR 723

Query: 400 NDLLSLD 406
             LLS++
Sbjct: 724 TKLLSIE 730


>UniRef50_Q09830 Cluster: Uncharacterized protein C4G8.04; n=1;
           Schizosaccharomyces pombe|Rep: Uncharacterized protein
           C4G8.04 - Schizosaccharomyces pombe (Fission yeast)
          Length = 772

 Score = 89.8 bits (213), Expect = 3e-16
 Identities = 66/232 (28%), Positives = 109/232 (46%), Gaps = 6/232 (2%)

Query: 185 KRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDT--SPE--KKLYASYIKAKSACEKVIRRD 240
           K+R    R+LV+ GVP  ++  VW   +G     SP   ++L +   + +SA    I  D
Sbjct: 491 KKRWHKFRELVKNGVPLCYKAKVWLECSGAYQLHSPGYYEELLSRTDEVESASVAQIDMD 550

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI-VGLLLMQMPEEEAF 299
           I RT  ++ FF  K G G   L  ++ AYS H+  +GYCQG   I   LLL+   EE+AF
Sbjct: 551 INRTMAKNVFFGGK-GPGIPKLRRILVAYSRHNPHIGYCQGMNVIGAFLLLLYASEEDAF 609

Query: 300 AVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
            +L+ I++       F P +         L++ V+E LP+++ H +         +    
Sbjct: 610 YMLMSIIENVLPPKYFTPDLMTSRADQLVLKSFVKESLPEIYSHLELLGVDLDAISFHWF 669

Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESIL 411
                      ++ RI D+   +G   +F+VAL +L   K  +L+ +  S +
Sbjct: 670 LSVYTDTLPTNISFRIFDMLFCDGYVCLFRVALTILKSLKQQILACNSSSAI 721


>UniRef50_Q6ZT07 Cluster: TBC1 domain family member 9; n=76;
           Deuterostomia|Rep: TBC1 domain family member 9 - Homo
           sapiens (Human)
          Length = 1266

 Score = 89.8 bits (213), Expect = 3e-16
 Identities = 64/225 (28%), Positives = 111/225 (49%), Gaps = 12/225 (5%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV----DTSP---EKKLYASYIKAKSACEKVIRR 239
           R +  R+LV +G+P   RG +W LL+G      T P   E  +  S  K   A E+ I R
Sbjct: 504 RTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEE-IER 562

Query: 240 DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAF 299
           D+ R+ PEH  F+ + G+   +L  V+ AY+  +  +GYCQ    +  +LL+   EEEAF
Sbjct: 563 DLHRSLPEHPAFQNEMGIA--ALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAF 620

Query: 300 AVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
            +LV + ++  + D +   +    +     E L ++ +P L+   Q     +++ +    
Sbjct: 621 WLLVALCER-MLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTI-SLSWF 678

Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
                       A  ++D F  EGI+++F++ALA+L    + LL+
Sbjct: 679 LTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLN 723


>UniRef50_Q5CZG9 Cluster: TBS1 protein; n=2; Paramecium
           tetraurelia|Rep: TBS1 protein - Paramecium tetraurelia
          Length = 773

 Score = 88.6 bits (210), Expect = 7e-16
 Identities = 54/235 (22%), Positives = 109/235 (46%), Gaps = 3/235 (1%)

Query: 185 KRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKVIRRDIART 244
           K ++  +  L + G+P   R  +W ++ G +    ++LYA Y+K     ++ IR DI R 
Sbjct: 498 KNKSMLLMILWKLGLPDFTRRTLWPIIIGNNLKIREELYAYYVKDSKIIQESIRGDIERA 557

Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVK 304
             ++ F  +   +  + L N++ A+S +  + GY      I  +L+  + E + F  LV 
Sbjct: 558 KQQYPFITD---VKAKELSNILHAFSNYRPDFGYIPDLIDIAVVLIKHLQEYDCFQALVN 614

Query: 305 IMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXX 364
           ++ Q+    +F+  + ++   +   E  +Q +LP +H H ++    T LY          
Sbjct: 615 LLHQYHFLSVFQNDIRQIEWRLRFFEENLQRILPFVHNHLKAIKLETKLYLMKWFLKIFL 674

Query: 365 XXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELP 419
                P+  R+ D FL EG   +FKV +  L   + +L   +++ +++ +    P
Sbjct: 675 HQFKFPMLSRLWDNFLLEGEIYLFKVGICYLKYFQIELKMSNLDEVVRILTNWQP 729


>UniRef50_A4RBP4 Cluster: Putative uncharacterized protein; n=2;
           Sordariomycetes|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 1186

 Score = 88.6 bits (210), Expect = 7e-16
 Identities = 66/239 (27%), Positives = 114/239 (47%), Gaps = 10/239 (4%)

Query: 172 LWGR-LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEK-KLYASYIK 228
           LW   L  N  +    R      L+R G+P+  RG +W+L +G V    E   +Y   ++
Sbjct: 263 LWAEYLRDNGRNFTLLRQPTFHKLIRVGLPNRLRGEMWELTSGSVYLRLENPSMYEETLE 322

Query: 229 AKSACEKV----IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
             S  E +    I +D+ R+ PE+  ++++ G+ +  L  V+ AYS  + +VGYCQ    
Sbjct: 323 KFSGQESLAIDEIEKDLNRSLPEYPGYQDQIGINR--LRRVLTAYSWVNADVGYCQAMNI 380

Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
           +V  LL+ M E +AF +L  +  +  +   +  +M    L     E+LV++ +P L  H 
Sbjct: 381 VVAALLIYMSEVQAFFLLTALCDR-LVPGYYSTTMYGTLLDQKVFESLVEKTMPILWEHL 439

Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
                  S+ +                A R++DVF  EG +++F+V LA+L +   +LL
Sbjct: 440 VKSDVQLSVVSLPWFLSLYINSMPLVFAFRVLDVFFVEGPKVLFQVGLAILRINGEELL 498


>UniRef50_Q21928 Cluster: Putative uncharacterized protein R11B5.1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein R11B5.1 - Caenorhabditis elegans
          Length = 614

 Score = 87.8 bits (208), Expect = 1e-15
 Identities = 65/261 (24%), Positives = 110/261 (42%), Gaps = 22/261 (8%)

Query: 175 RLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIK------ 228
           +++  WE    + ++  R+L  QGVP   RG +W L  G      K+LY   +       
Sbjct: 277 QILPKWEE--MKDSKRCRELWWQGVPAKVRGELWFLTIGNQIEITKELYDGLMDQAEEKI 334

Query: 229 AKSACEK-------------VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
           AK   E+              I  D  RT+     F +KDG   + L  ++ AY++   +
Sbjct: 335 AKQLAEQNKNSAERKETSVTQIHLDATRTFTSLGMF-QKDGPYYDHLLKLLSAYAILRPD 393

Query: 276 VGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQE 335
           +GY Q   FI  +LL+QM    AF     ++ +      F     ++       +  +++
Sbjct: 394 IGYVQSMTFIAAVLLIQMDPYPAFISFANLLDRSLQSAFFGLKQPQMTEYFIAYDRYLEQ 453

Query: 336 LLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
            LP LH H         LY                + CRI DV+  +G E +FK AL +L
Sbjct: 454 ELPALHQHLDKLDVRPDLYLIEWTFAMYAKSLPLDVTCRIWDVYFRDGEEFLFKAALGIL 513

Query: 396 TLGKNDLLSLDMESILKYIQK 416
            + +  LL++D +  ++++ K
Sbjct: 514 RMYEPKLLTMDFDDCVEFLTK 534


>UniRef50_Q4RWK8 Cluster: Chromosome 3 SCAF14987, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 3
           SCAF14987, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 885

 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 66/252 (26%), Positives = 110/252 (43%), Gaps = 29/252 (11%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
           W  +  +W+   K R Q V+   R+G+P   R   WQLL+     ++ +P +        
Sbjct: 327 WLDMFHHWDKWIKHRFQKVKLRCRKGIPSSLRAKAWQLLSNSQELLEANPGRFEELEREP 386

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
            ++    +I +D+ R +P H+ F  + G GQ+ LF ++KAY+++  + GYCQ    +  +
Sbjct: 387 GEAKWLDIIEKDLHRQFPFHEMFAARGGHGQQDLFRILKAYTVYRPDEGYCQAQAPVAAV 446

Query: 289 LLMQMPEEE------------AFAV---LVKIMQQH-----RMRDMFKPSMAELGLCMFQ 328
           LLM MP E              FA+      + QQ      ++ + F P     GL   Q
Sbjct: 447 LLMHMPAEVRDTSNPRPQHPIMFALTPGYASVPQQAFWCLVQICEKFLPGYYSAGLEAIQ 506

Query: 329 LE-----NLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG 383
           L+     +L++   P  + H +       LY                   R+ D+F  EG
Sbjct: 507 LDGEIFFSLLRRTCPMAYRHLKKFKIDPILYMTEWFMCIFSRTLPWACVLRVWDMFFCEG 566

Query: 384 IEIVFKVALALL 395
           ++IVF+V L LL
Sbjct: 567 VKIVFRVGLVLL 578


>UniRef50_Q4RTM1 Cluster: Chromosome 2 SCAF14997, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
           SCAF14997, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1053

 Score = 87.0 bits (206), Expect = 2e-15
 Identities = 58/215 (26%), Positives = 99/215 (46%), Gaps = 10/215 (4%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK------KLYASYIKAKSACEKVIRRD 240
           R +  + LV  G+P   RG +W  L+   +  E       KL    +   S   + I RD
Sbjct: 387 RTEKTQRLVAMGIPESLRGELWMTLSDASSELESHQGYYSKLVQQSMGHSSLATEEIERD 446

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
           + R+ P+H  F+   G+   +L  V+ AY+  + ++GYCQ    +  +LL+   EEEAF 
Sbjct: 447 LHRSLPDHPAFQNPTGIA--ALRRVLTAYAHRNPKIGYCQSMNILASVLLLYAREEEAFW 504

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           +LV ++ +  + D F   +    +     E L++E LP+L  H    S  +S+       
Sbjct: 505 LLV-VVCERMLPDYFNRRVIGAQVDQSVFEELIRERLPELAEHVPDLSALSSVSLSWFLT 563

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
                       C ++D F   GI+ +F++ LA+L
Sbjct: 564 LFLSVLPFHSAVC-VVDCFFFHGIKAIFQLGLAVL 597


>UniRef50_Q7YYL8 Cluster: GTPase activator protein, possible; n=3;
           Cryptosporidium|Rep: GTPase activator protein, possible
           - Cryptosporidium parvum
          Length = 414

 Score = 87.0 bits (206), Expect = 2e-15
 Identities = 51/182 (28%), Positives = 88/182 (48%), Gaps = 4/182 (2%)

Query: 236 VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM--QM 293
           +I  D+ RT+PE + F+  D   QE LF V+ A + H  +VGYCQG  FI  LLL+    
Sbjct: 199 LISIDVPRTFPELNIFR--DQASQECLFRVLNATANHIPDVGYCQGMNFIAALLLITSNF 256

Query: 294 PEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSL 353
            +E +F  L+ I++ + +   +K     L   +   + + Q  +P L  HFQ +     +
Sbjct: 257 DQERSFYSLILILETYGLSGFYKDQFPLLTKYIQAFDTMFQTNIPKLWKHFQDEGIFDPV 316

Query: 354 YAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKY 413
           Y                    I D  L+ G++ +  +A+ALL   ++ L+   ME+I+++
Sbjct: 317 YLHPWFLTLFVSTLPLKTVVIIWDYLLANGLQSLISIAIALLKTLESSLIGQSMENIIQF 376

Query: 414 IQ 415
            +
Sbjct: 377 FK 378


>UniRef50_Q7R5W8 Cluster: GLP_81_109382_107820; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_81_109382_107820 - Giardia lamblia
           ATCC 50803
          Length = 520

 Score = 87.0 bits (206), Expect = 2e-15
 Identities = 61/240 (25%), Positives = 118/240 (49%), Gaps = 18/240 (7%)

Query: 169 LWSLWGRLVSNWESEWK--RRNQW--VRDLVRQGVPHHFRGIVWQLLAGV-------DTS 217
           L   W  +++NW++  K  + N +  +++L R+G+P  +R  VW  L          +  
Sbjct: 172 LMQQWEIIITNWKAHNKTLQPNDYRAIKELGREGIPDCYRQDVWPRLLNAQNLYQQNEKY 231

Query: 218 PEKKLYASYIKAKSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
            ++  + +Y++ +   E V  I +DI RT P+H +F+  +G  +++LF V+KA++ HD +
Sbjct: 232 TDRSTFGAYLQREICSEVVTQIGKDIDRTLPKHVYFRSLEG--RQALFLVLKAFASHDED 289

Query: 276 VGYCQGSGFIVGLLLMQMPE-EEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQ 334
           + YCQG      +LL+ + +   AF    + ++  R  +M+ PS+  L L    L +L++
Sbjct: 290 ITYCQGMNCPAAILLIYIRDIPLAFWCFYRFIK--RFGNMYLPSLYGLKLRALTLMHLLR 347

Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
           E+ P +  + Q                         ++ RI D  L EG + +F+ A+A+
Sbjct: 348 EIEPKIASYLQEVGIDLLCITPGWFMTVFSNCLKFSVSLRIFDSLLCEGEKAIFRAAVAI 407


>UniRef50_UPI0000F1EDBF Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 1175

 Score = 86.6 bits (205), Expect = 3e-15
 Identities = 59/222 (26%), Positives = 102/222 (45%), Gaps = 10/222 (4%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTS--PEKKLYASYIKA----KSACEKVIRRD 240
           R++ +R LV  G+P   RG +W   +   +S       YA  ++      S   + I RD
Sbjct: 612 RSEKIRTLVSLGLPESLRGELWLHFSDASSSLAAHPNYYADLLEKCRGESSVATEEIERD 671

Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
           + R+ PEH  F+ + G+   +L  V+ AY+  +  +GYCQ    +  ++L+ + EEEAF 
Sbjct: 672 LHRSLPEHPAFQSETGIS--ALRRVLTAYAYRNPSIGYCQSMNILASVMLLYLREEEAFW 729

Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
           +LV + ++  + D F   +    +     E L++E LPDL       S   S        
Sbjct: 730 LLVTVCER-MLPDYFNRRVIGAQVDQSVFEELIRERLPDLAAAVGDVSPLASASLTWFLT 788

Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
                       C ++D F  +GI  +F+++LA+L     +L
Sbjct: 789 LFVSVLPFRSALC-VLDGFFYQGIRAIFQISLAVLEANAAEL 829


>UniRef50_Q5KGA6 Cluster: GTPase activating protein, putative; n=2;
           Filobasidiella neoformans|Rep: GTPase activating
           protein, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 647

 Score = 86.6 bits (205), Expect = 3e-15
 Identities = 76/269 (28%), Positives = 115/269 (42%), Gaps = 22/269 (8%)

Query: 162 GTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA--------- 212
           G N  E  WS  G    N     K  N+     V +G+P  +R   W   A         
Sbjct: 335 GGNIIEWQWSRDGEGAKNLMKRTKLANR-----VYKGIPDRWRMAAWWTFAEEQAQKWNG 389

Query: 213 -GVDTSPEKKLYASYIKA---KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKA 268
            G   S  ++L + Y +A    S  +  I  D+ RT   H  F  + G GQ +L++V+ A
Sbjct: 390 KGKGKSTAQELTSDYTEAVNLPSTFDVQIDLDVPRTISGHTMFVTRYGTGQRNLWHVLHA 449

Query: 269 YSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQ 328
           +S      GY QG G IV  LL     E A++++V++   + M ++F+P    L    + 
Sbjct: 450 FSQRCPTCGYVQGMGPIVATLLCYYDPERAYSLMVRLHDVYGMHEIFEPGFPGLLEAFYV 509

Query: 329 LENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVF 388
            E L++ L+PDL+  FQ    ST+ +                   RI DV   EG + + 
Sbjct: 510 QERLMEWLIPDLYQSFQRNMISTTAWGTKWYITLFVNTVPFSQQLRIWDVLWMEGRDAII 569

Query: 389 KVALALLTLGKNDLL---SLDMESILKYI 414
             +LA+L     DLL   +   ESIL  +
Sbjct: 570 ITSLAIL-WSFRDLLAAPNASFESILSLL 597


>UniRef50_Q8IZP1 Cluster: TBC1 domain family member 3; n=79;
           Catarrhini|Rep: TBC1 domain family member 3 - Homo
           sapiens (Human)
          Length = 549

 Score = 86.6 bits (205), Expect = 3e-15
 Identities = 58/227 (25%), Positives = 106/227 (46%), Gaps = 9/227 (3%)

Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
           S W  ++ +WE ++K   + + D   +G+P + RG +W +L  ++    K      I   
Sbjct: 76  SKWVDMLGDWE-KYKSSRKLI-DRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKE 133

Query: 228 KAKSACEKVIR--RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
           K K + E + R  RD++ T  +H FF+++ G  Q  L +++ AY  ++ EVGYC+    I
Sbjct: 134 KGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHI 193

Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
             L L+ +PEE+AF  LV+++  ++H ++    P+   +     Q E++V    P    H
Sbjct: 194 AALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGH 253

Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKV 390
              +                       L  R+ DV+L EG + +  +
Sbjct: 254 QDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300


>UniRef50_UPI0000DB6E56 Cluster: PREDICTED: similar to CG7324-PA;
           n=3; Endopterygota|Rep: PREDICTED: similar to CG7324-PA
           - Apis mellifera
          Length = 1115

 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 60/217 (27%), Positives = 98/217 (45%), Gaps = 10/217 (4%)

Query: 194 LVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK--SACE--KVIRRDIARTYPE 247
           L+ QGVP   RG VW   +G   +      LY S +      +C+  + I RD+ R+ PE
Sbjct: 483 LIIQGVPQSLRGEVWLTFSGALNEMVMNPGLYKSLVDQSLGKSCQANEEIERDLHRSLPE 542

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
           H  F+   G+   +L  V+ AY+  + ++GYCQ    +  +LL+   EE AF  L  + +
Sbjct: 543 HPAFQSDTGIS--ALRRVLSAYAWKNPQIGYCQAMNIVASVLLIYCSEESAFWQLCNVCE 600

Query: 308 QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
              + D +   +    +    LE L  E LP LH   Q       + +            
Sbjct: 601 S-LLPDYYDRRVVGALVDQGLLEELAAEHLPTLHARLQELGL-IKVISLSWFLTIFLSVM 658

Query: 368 XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
               A  IMD F  +G +++F++AL +L   ++ LL+
Sbjct: 659 PTSSAVNIMDCFFYDGAKVIFQIALTVLEWNQDKLLN 695


>UniRef50_Q4SM04 Cluster: Chromosome 13 SCAF14555, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
           SCAF14555, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1057

 Score = 85.8 bits (203), Expect = 5e-15
 Identities = 57/220 (25%), Positives = 93/220 (42%), Gaps = 9/220 (4%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP-----EKKLYASYIKAK----SACEKVI 237
           R+  ++ L+R GVPH  R  VWQ              E   Y + +       +   K I
Sbjct: 632 RSPELKALIRCGVPHEHRSRVWQWCVSSRVKKFRDNLEPDYYETLLNVARDKPNPASKQI 691

Query: 238 RRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE 297
             D+ RT P +  +      G + L NV+ A+S  + ++GYCQG   +  + L+ + +E+
Sbjct: 692 ELDLLRTLPNNKHYSSPGAGGIQKLRNVLMAFSWRNPDIGYCQGLNRLAAIALLYLDQED 751

Query: 298 AFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXX 357
           AF  LV I++    RD +  ++    +      +L+ E LP LH HF+      SL    
Sbjct: 752 AFWSLVAIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHAHFEQHKVDFSLITFN 811

Query: 358 XXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTL 397
                        +  +I D FL EG ++  +     L L
Sbjct: 812 WFLVVFVDSVVSDILFKIWDAFLFEGPKVRSRTVRTCLQL 851


>UniRef50_Q4DET3 Cluster: GTPase activator protein, putative; n=2;
           Trypanosoma cruzi|Rep: GTPase activator protein,
           putative - Trypanosoma cruzi
          Length = 562

 Score = 85.8 bits (203), Expect = 5e-15
 Identities = 67/290 (23%), Positives = 126/290 (43%), Gaps = 22/290 (7%)

Query: 183 EWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK------LYASYIKAKSACEKV 236
           E+ RR  W       G+P H RG++W  ++GV +  ++       L   +   +    + 
Sbjct: 129 EFMRRAMW-----HHGIPQHLRGVLWLTISGVASKMDENQGFCRALLKRHGYIRGEYAEA 183

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
           I +D+ RT+PEH +F +  GLG     NV+ A    +  + YCQ   ++V  +L+ + +E
Sbjct: 184 IEKDLHRTFPEHRYFAD-GGLGIRKARNVLHALCWRNPLLNYCQSFNYLVAFILLVVDDE 242

Query: 297 EA-FAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
           E+ F ++  +++     D++  S+    +    L+ L+Q+ LP L  HF    F      
Sbjct: 243 ESTFWLMCHLLENLLPNDLYSESLIGTKVDQLVLQALLQQRLPRLAQHFSEVHFEVETLV 302

Query: 356 XXXXXXXXXXXXXXPLACRIMDVFL------SEGIEIVFKVALALLTLGKNDLLSL-DME 408
                             R+ D  L      SE   +  +V LA+L L +N+LL   D  
Sbjct: 303 SAWVMALFINVVPVQTLLRVWDCLLAGWSHSSEHSCVPLEVVLAVLKLHQNELLRCNDAG 362

Query: 409 SILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQ 458
            +L  +  +   K   D    + L   ++++P  ++++ +       +EQ
Sbjct: 363 DVLMCL--DHATKRLFDAEKLVRLIREMRLSPSNVRQMRRSARPTVAEEQ 410


>UniRef50_A2EN43 Cluster: TBC domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: TBC domain containing
           protein - Trichomonas vaginalis G3
          Length = 344

 Score = 85.8 bits (203), Expect = 5e-15
 Identities = 62/278 (22%), Positives = 120/278 (43%), Gaps = 14/278 (5%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LY 223
           + D+W+ + +     E  + + +++ + L+R G+P   R ++W  + G++    K   +Y
Sbjct: 36  QSDVWTNYIKSAGGIEKIYVKSSKF-KKLIRAGIPQGLRPMIWGQILGLEEKISKSNDIY 94

Query: 224 ASYIKAKSACEK----VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYC 279
               K      K    +I  D+ RT      F + + L ++ L  ++ A+++   E+GYC
Sbjct: 95  HRSYKMVEVVPKNYRDIIENDLKRT------FNDAENLSKDILRKILIAFAVTHPEIGYC 148

Query: 280 QGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPD 339
           Q   FI  LLL+ + +E A+  L  I++     D +   M    + +    +++ E  P+
Sbjct: 149 QSLNFIAALLLVVLGDEPAYHALCTIVEDFLPADYYTAGMHGFRVDLQLFNSILHERTPE 208

Query: 340 LHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGK 399
           +  H         L A              P   RI D FL EG +I+++VA+  L + +
Sbjct: 209 VWKHATKLHHEWMLTASGWLLTVFSNSFPIPTVLRIWDSFLVEGPKIIYRVAVGFLRIHQ 268

Query: 400 NDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVK 437
            + L     S    +      K   DQ   M +A+ ++
Sbjct: 269 EEFLKAQKLSQFTNLLSNCE-KNMIDQDQLMEMAFGLR 305


>UniRef50_UPI00015B49B5 Cluster: PREDICTED: similar to TBC1 domain
           family, member 9; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to TBC1 domain family, member 9 -
           Nasonia vitripennis
          Length = 1417

 Score = 85.4 bits (202), Expect = 6e-15
 Identities = 61/216 (28%), Positives = 98/216 (45%), Gaps = 10/216 (4%)

Query: 194 LVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK--SACE--KVIRRDIARTYPE 247
           LV  G+P + RG VW   +G   + +    LY S +       C+  + I RD+ R+ PE
Sbjct: 467 LVITGIPQNLRGEVWLTFSGALNEMAVNPGLYKSLVDQSLGKTCQANEEIERDLHRSLPE 526

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
           H  F+   G+   +L  V+ AY+  + ++GYCQ    +  +LL+   EE AF  L  + +
Sbjct: 527 HPAFQSDIGIS--ALRRVLSAYAYRNPQIGYCQAMNIVASVLLIYCSEESAFWQLCNVCE 584

Query: 308 QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
              + D +   +    +    LE L QE LP L+V  Q       + +            
Sbjct: 585 S-LLPDYYDRRVVGALVDQGLLEELAQEHLPALYVKLQELGL-IRVISLSWFLTIFLSVM 642

Query: 368 XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
               A  IMD F  +G +++F+VAL +L   +  LL
Sbjct: 643 PTSSAVNIMDCFFYDGAKVIFQVALTVLEWNQEKLL 678


>UniRef50_UPI0000DBF1CE Cluster: similar to FLJ20298 protein isoform
           a (predicted) (RGD1563084_predicted), mRNA; n=5; Rattus
           norvegicus|Rep: similar to FLJ20298 protein isoform a
           (predicted) (RGD1563084_predicted), mRNA - Rattus
           norvegicus
          Length = 1067

 Score = 85.0 bits (201), Expect = 8e-15
 Identities = 70/276 (25%), Positives = 123/276 (44%), Gaps = 21/276 (7%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRG--IVWQLLAGV--DTSPEKKLYASYIK 228
           W  L S        R +  R LV +G+P   RG  +   + AG   D +     YA  ++
Sbjct: 485 WNVLFSECGQVRLSRTKNTRGLVARGIPQTLRGGDVNAIVFAGAVNDMAANPGYYAEVVE 544

Query: 229 ----AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
                 +   + I RD+ R+ PEH  F+   G+   +L  V+ AY+  + ++GYCQ    
Sbjct: 545 QSLGTSNLATEEIERDLRRSLPEHPAFQSDTGIS--ALRRVLTAYAYRNPKIGYCQAMNI 602

Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
           +  +LL+   EEEAF +LV + ++  + D F   +    +     E L+++ LP L  H 
Sbjct: 603 LTSVLLLYAKEEEAFWLLVAVCER-MLPDYFNRRIIGALVDQAVFEELIRDHLPQLTDHM 661

Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
              +F +S+ +                A  ++D F  +GI+ + ++ LA+L    + LL+
Sbjct: 662 TDMTFFSSV-SLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLT 720

Query: 405 L--DMESIL-------KYIQKELPLKAEADQAAFMN 431
              D E++          I K+ PL +   Q + +N
Sbjct: 721 CKDDAEAVTALNRFFDNVINKDSPLPSNVQQGSNIN 756


>UniRef50_Q4SJ91 Cluster: Chromosome 4 SCAF14575, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 4 SCAF14575, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 463

 Score = 85.0 bits (201), Expect = 8e-15
 Identities = 41/128 (32%), Positives = 68/128 (53%), Gaps = 4/128 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKL----YASYIK 228
           W  ++++W+    ++++ V++  ++G+P   RG  W  L G     E+          + 
Sbjct: 56  WLEMLNSWDKWMAKKHKKVKERCQKGIPPSLRGRAWLYLTGGKVKREQNAGKFQELQSLP 115

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
                  +I RD+ R +P H+ F  + G GQ+SLF+V+KAYSL+  + GYCQ    I  +
Sbjct: 116 GDPTWVDIIERDLHRQFPFHEMFSARGGHGQQSLFDVLKAYSLYRPDEGYCQAQAPIAAV 175

Query: 289 LLMQMPEE 296
           LLM MP E
Sbjct: 176 LLMHMPAE 183



 Score = 39.1 bits (87), Expect = 0.52
 Identities = 31/137 (22%), Positives = 62/137 (45%), Gaps = 4/137 (2%)

Query: 296 EEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
           ++AF VLV+I +++ +   +   +  + L    L  L+ ++ P  H H +       +Y 
Sbjct: 263 KDAFWVLVQICEKY-LPGYYSTGLEAIQLDGEILYALLPKVSPVAHRHLKKHHLEPIMYM 321

Query: 356 XXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLLSLDMESILKY 413
                             R+ D+FL EG++I+F+V L LL  TL   + L    + + + 
Sbjct: 322 TEWFMCAFSRTLPWASVLRVWDMFLCEGVKILFRVGLILLKCTLSSQEKLK-SCQGLYET 380

Query: 414 IQKELPLKAEADQAAFM 430
           +Q    ++ +  Q +F+
Sbjct: 381 MQVLRAIEPQYTQESFL 397


>UniRef50_A0CUC2 Cluster: Chromosome undetermined scaffold_28, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_28,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 276

 Score = 85.0 bits (201), Expect = 8e-15
 Identities = 62/233 (26%), Positives = 104/233 (44%), Gaps = 10/233 (4%)

Query: 221 KLYASYIKAKSACEKV---IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVG 277
           ++Y   +KA+   EK+   I++D  RT+  H +FK+ +  GQE L++V+ A S+   E+G
Sbjct: 34  QIYMLLLKAQPLPEKIQDDIKKDQNRTFTRHSYFKDPNK-GQEQLYSVLHALSIQYPEIG 92

Query: 278 YCQGSGFIVGLLLMQM--PEEEAFAVLVKIMQQHRMR--DMFKPSMA-ELGLCMFQLENL 332
           Y QG  F+VG  L+     EE+ F  +  I Q  R    ++++        LC    ENL
Sbjct: 93  YAQGMNFVVGFCLIMSGGNEEDVFWFINFINQNERFNWWEIYRGEFTFAQNLCQIFQENL 152

Query: 333 VQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL 392
            Q  LP L  HFQ        Y                +     D  L+  I  + K+ L
Sbjct: 153 -QRQLPQLFNHFQKNGIFAFQYFWQWILTQFLYSFPIEIVIFFWDFILATDIYSILKIGL 211

Query: 393 ALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKK 445
           A L   +N L+  D+  + +Y   +   +   D    +N A ++++   + +K
Sbjct: 212 AFLRDMENILIGYDLTQLSEYFSYQTKKQNNIDITDLLNKAKNIEITMSEEQK 264


>UniRef50_UPI0000E247DD Cluster: PREDICTED: TBC1 domain family,
           member 3B isoform 3; n=10; Catarrhini|Rep: PREDICTED:
           TBC1 domain family, member 3B isoform 3 - Pan
           troglodytes
          Length = 452

 Score = 84.6 bits (200), Expect = 1e-14
 Identities = 50/155 (32%), Positives = 86/155 (55%), Gaps = 9/155 (5%)

Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
           S W  ++ +WE ++K   + + D V +G+P + RG +W +L  V+    K      I   
Sbjct: 76  SKWVDMLGDWE-KYKSSRKLI-DRVYKGMPMNIRGPMWSVLLNVEEMKLKNPGRYQIMKE 133

Query: 228 KAKSACEKVIR--RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
           K K + E + R  RD++ T  +H FF+E+ G  Q  L +V+ AY  ++ EVGYC+    I
Sbjct: 134 KGKRSSEHIQRIDRDVSGTLRKHIFFRERYGTKQRELLHVLLAYEEYNPEVGYCRDLSHI 193

Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPS 318
             L L+ +PEE+AF  LV+++  ++H ++    P+
Sbjct: 194 AALFLLYLPEEDAFWALVQLLASERHSLQGFHSPN 228


>UniRef50_UPI00005A604F Cluster: PREDICTED: similar to USP6
           N-terminal like; n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to USP6 N-terminal like - Canis
           familiaris
          Length = 752

 Score = 84.6 bits (200), Expect = 1e-14
 Identities = 51/172 (29%), Positives = 81/172 (47%), Gaps = 3/172 (1%)

Query: 268 AYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLC 325
           A  L   EVGYCQG   I  +LLM +PEE+AF  L ++M   +H M   F P   +L   
Sbjct: 196 ARQLQGSEVGYCQGMSEITAILLMFLPEEDAFWALAQLMTDDRHAMHGFFVPGFPKLLRF 255

Query: 326 MFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIE 385
               E ++Q  LPDL  H + +   T +Y                L  ++ D ++ +G  
Sbjct: 256 QAHHERVLQRALPDLRKHMEEEQMCTGIYTPKWFLQCFLGRTPFLLTLKLWDAYILDGER 315

Query: 386 IVFKVALALLTLGKNDLLSLDMESILKYIQKELPLK-AEADQAAFMNLAYSV 436
           ++  +A  +L + +  LL L +E + +++Q  L    A  D+A   +L  SV
Sbjct: 316 VLTAMAYTILKVHRKHLLKLPLEGLREFLQDSLAQPWALEDEAVLRHLWASV 367


>UniRef50_Q5CLC5 Cluster: GTPase activator protein; n=3;
           Cryptosporidium|Rep: GTPase activator protein -
           Cryptosporidium hominis
          Length = 408

 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 67/288 (23%), Positives = 126/288 (43%), Gaps = 19/288 (6%)

Query: 179 NWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKVIR 238
           NW +      + +  L   G+P   RG VW  L G D          + +   + +K I 
Sbjct: 122 NWANYKDFTQKKLLKLCISGIPSDIRGEVWCYLLGSDRMLRNNSNVYFNELNGSIDKNIE 181

Query: 239 R----DIARTYPEHDFFKEKDGLGQE-SLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQM 293
                D+ RT+P   ++       +  +L  V+ A++ +D+ +GYCQ   FI  +LL+ M
Sbjct: 182 NQIILDLHRTFPNSKYYSNSSNFNKVGTLSRVLYAFASYDKVIGYCQSMNFIAAILLINM 241

Query: 294 PEEEAFAVLVKIMQQHRMRDMFKPSMAEL---------GLC--MFQLENLVQELLPDLHV 342
            EE AF  LV+++  +R ++    S  +L         G+   +  LE L ++ +P +  
Sbjct: 242 KEEAAFWSLVQLVSSNRNKEFMVCSWGDLETYYGERMDGIIRDIAILETLCRKFIPKVSQ 301

Query: 343 HFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDL 402
             ++   +   +A                   I+D+    G +++F +++ALL + K  L
Sbjct: 302 KLENIGINFQWFALEWFLCFFVTSLPLKSIMEILDLIFCFGSDVLFNISIALLDINKKKL 361

Query: 403 L-SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKE 449
           L S++ME  ++ I K +  K   D    +  A    ++   ++KL +E
Sbjct: 362 LSSVNMEECME-ILKNI-TKNITDSTKIIRKAMKYNISSNYIQKLREE 407


>UniRef50_A0DIR4 Cluster: Chromosome undetermined scaffold_52, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_52,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 529

 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 71/269 (26%), Positives = 126/269 (46%), Gaps = 28/269 (10%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSA 232
           W  ++ N      +  Q  + ++ Q + +  R   W  ++  + + ++    SY K K A
Sbjct: 241 WQIILKNKSFTGYKVQQIHQSIMLQTMEYDIRRQWWIFVSNQEQNKKELRNQSYQKLKKA 300

Query: 233 --CEKV-IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLL 289
               K+ I +D+ART   HD F  ++   Q+SL N++ AY+ +D+E+GY QG   IV  L
Sbjct: 301 DTLHKIQIEKDVARTII-HDMFNMRN---QQSLKNILIAYANYDKELGYVQGLNIIVANL 356

Query: 290 LM------------------QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN 331
           L+                  +  +E  F + + IM+    R +F      L L +  LE 
Sbjct: 357 LVCYDLSVNDQQLNDFEVMDEERDETVFFIFLYIMKDQNWRVVFLEGFEGLRLKIDVLEQ 416

Query: 332 LVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXP--LACRIMDVFLSEGIEIVFK 389
           ++++ +P+LH HF  +   T  +               P   +  I+D+FL EG EI+ K
Sbjct: 417 MMKKKIPELHRHFYDEGI-TDFFPFFSRFYMTLLMYNIPWRFSGMILDLFLIEGEEIIHK 475

Query: 390 VALALLTLGKNDLLSLDMESILKYIQKEL 418
           + LA+L+  KN L++ +   I  + Q++L
Sbjct: 476 LILAMLSYHKNKLITRNYSDIRTFCQEQL 504


>UniRef50_Q873F9 Cluster: Putative uncharacterized protein B10C3.030;
            n=3; Sordariomycetes|Rep: Putative uncharacterized
            protein B10C3.030 - Neurospora crassa
          Length = 1137

 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 66/236 (27%), Positives = 101/236 (42%), Gaps = 11/236 (4%)

Query: 192  RDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKV-----IRRDIARTYP 246
            R L+  G+P  +R  +W    G         Y   +      +       I+ DI RT  
Sbjct: 794  RQLILGGIPVAYRSKIWSECCGAKALRIPGYYDDLVNQAGDQDDPQVVAQIKADITRTLT 853

Query: 247  EHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMP-EEEAFAVLVKI 305
            ++ FF++  G G   L  V+ AY+  + +VGYCQG   +V  LL+  P  E+AF +LV I
Sbjct: 854  DNIFFRK--GPGVNKLNEVLLAYARRNPDVGYCQGMNLVVANLLLITPCAEDAFWILVSI 911

Query: 306  MQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXX 365
            ++     + F  S+         L   V E+LP L  HF+    +               
Sbjct: 912  VENILPPNYFDHSLLASRADQQVLRQYVSEVLPKLSAHFEELGITLETMTFQWFLSVFTD 971

Query: 366  XXXXPLACRIMDVFL--SEGIEIVFKVALALLTLGKNDLLSLDMES-ILKYIQKEL 418
                    R+ DV L   +G   +F+VALALL L +  LL+ D  + I  YI  ++
Sbjct: 972  CLSAEALFRVWDVLLCTHDGGVFLFQVALALLKLNERQLLACDSAAHIYSYINHQM 1027


>UniRef50_A5E5S6 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 767

 Score = 83.8 bits (198), Expect = 2e-14
 Identities = 59/222 (26%), Positives = 111/222 (50%), Gaps = 13/222 (5%)

Query: 195 VRQGVPHHFRGIVWQLLAGVDTSPEKK----LYASYIKAKSA-CEKVIRRDIARTYPEHD 249
           ++QG+P+  R  +W  L  ++++   K    +Y ++  + SA   + I++D+ RT+P   
Sbjct: 147 LKQGIPNSLRSAIWTKLFLLNSATVPKSMSLIYHNFQHSYSAEVSEQIKKDLNRTFPTIP 206

Query: 250 FFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPE--EEAFAVLVKIMQ 307
           FFK+   +    L  ++  Y+ +D E+GYCQG  F+VG+L        E  F  L  +M 
Sbjct: 207 FFKQPQTIND--LSTILNVYANYDAELGYCQGLLFLVGVLYHHFKGDCEMTFFALTNVMD 264

Query: 308 -QHRMRDMFKPSMAELGLCMF--QLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXX 364
            +  + D+F P++    L  +  Q  N+ Q++  +L+ H    +  T+            
Sbjct: 265 LETELHDIFTPNLMSQTLSSWYRQFCNIFQQVDSELYNHLTGFTDMTTFLYQWWLTFKTS 324

Query: 365 XXXXXPLACRIMDVFLSEGIEI-VFKVALALLTLGKNDLLSL 405
                 +  R+MD  + +G ++ +FKV+LAL+ + K  L+SL
Sbjct: 325 HTPDTSIINRVMDFCMFQGWKLGIFKVSLALILVNKPILMSL 366


>UniRef50_UPI000065E779 Cluster: TBC1 domain family member 10A
           (EBP50-PDX interactor of 64 kDa) (EPI64 protein).; n=1;
           Takifugu rubripes|Rep: TBC1 domain family member 10A
           (EBP50-PDX interactor of 64 kDa) (EPI64 protein). -
           Takifugu rubripes
          Length = 437

 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 4/128 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKL--YASYIKAK 230
           W  ++++W+    ++++ V++  ++G+P   RG  W  L G     E+    Y   +  +
Sbjct: 54  WLEMLNSWDKWMAKKHKKVKERCQKGIPPSLRGRAWLYLTGGKVKREQNAGKYQELLSQQ 113

Query: 231 S--ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
                  +I RD+ R +P H+ F  + G GQ+ LF+V+KAYSL   + GYCQ    +  +
Sbjct: 114 GDPTWVDIIERDLHRQFPFHEMFSARGGHGQQGLFDVLKAYSLFRPDEGYCQAQAPVAAV 173

Query: 289 LLMQMPEE 296
           LLM MP E
Sbjct: 174 LLMHMPAE 181



 Score = 42.7 bits (96), Expect = 0.042
 Identities = 40/157 (25%), Positives = 71/157 (45%), Gaps = 6/157 (3%)

Query: 296 EEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
           ++AF VLV+I +++ +   +   +  + L    L  L+ ++ P  H H +  +    L  
Sbjct: 237 KDAFWVLVQICEKY-LPGYYSTGLEAIQLDGEILYALLHKVSPTAHRHLKKHNLEPVLCM 295

Query: 356 XXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLLSLDMESILKY 413
                             RI D+FL EG++I+F+V L LL  TLG  + L    + + + 
Sbjct: 296 TEWFMCAFSRTLPWASVLRIWDMFLCEGVKILFRVGLVLLKCTLGSQEKLK-SCQGLYET 354

Query: 414 IQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEY 450
           +Q    ++ +  Q +F  LA  V       K +EKE+
Sbjct: 355 MQLLRAIQPQYMQESF--LAQEVVELHVTEKDIEKEH 389


>UniRef50_A5KAZ5 Cluster: TBC domain containing protein; n=1;
           Plasmodium vivax|Rep: TBC domain containing protein -
           Plasmodium vivax
          Length = 553

 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 51/237 (21%), Positives = 108/237 (45%), Gaps = 17/237 (7%)

Query: 196 RQGVPHHFRGIVWQL-LAGVDTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKE- 253
           R+ +P   R ++W+L L G  T   + L+    + +S  E++I +D+ RT+P  D     
Sbjct: 67  RKFMPSEKRSLIWKLILLGESTHLSEDLFGELTRRRSTYERIIEKDVPRTFPHRDATANT 126

Query: 254 --------------KDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE-EA 298
                         +    QE LF+V+K  SL+ + VGYCQG  ++  +L + + ++   
Sbjct: 127 AADPTADPTATAVPRGPPPQEELFDVLKTCSLYFQNVGYCQGMNYVAAVLFLVLKDKLHT 186

Query: 299 FAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXX 358
               + +++   ++ M+     +L   ++QL+ L++   P L  + + +      ++   
Sbjct: 187 ARCFIALLKIFNLKGMYMHKFPQLKKTIYQLKILIRAYFPKLSSYLRRKKIKIDFFSINW 246

Query: 359 XXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQ 415
                          ++ D F   G++I+ K++L  L+  +  +LSL  E  L +++
Sbjct: 247 FMTLFSQDLTFEQTVKLWDSFFLFGVKILIKLSLIFLSHFERKILSLSYEEALTFLK 303


>UniRef50_A4VDB7 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 616

 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 65/279 (23%), Positives = 124/279 (44%), Gaps = 24/279 (8%)

Query: 192 RDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAK--SACEKVIRRDIARTYPEHD 249
           + L+ QG+P + R  VW++        ++ LY   ++       E  I +D+ RT+P H 
Sbjct: 122 QSLIEQGIPLNLRWNVWKVQLFNKDIYDEHLYEKLLQQPIDEHYEHAIMKDLPRTFPSHP 181

Query: 250 FFKEKD------------GLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMP--E 295
           +F+ K+              GQ+ L+NV+KA S+H   VGY QG  F+V  LLM     E
Sbjct: 182 YFQSKEPGGGGYLKISQLNQGQKQLYNVLKALSIHMPNVGYTQGMNFVVAFLLMMSAGNE 241

Query: 296 EEAFAVLVKIMQQHR--MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSL 353
            E+F + + + +        +F+ ++  + + +   E   + +LP+L+ +FQ+    + L
Sbjct: 242 NESFWIFLLLARDPNFLFMGLFEETLPLMHILICIFEKKFKIVLPELYEYFQNIMLDSML 301

Query: 354 YAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKY 413
           +                +  ++ D  +  G      + LAL    + + L  DME I   
Sbjct: 302 WVWKWFITVYLYSFPIEIVAKLWDYIIINGGLSTISLGLALAEYFQKEFLVRDMEDIQTL 361

Query: 414 IQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTV 452
           ++     +   D+ +   L ++      K++K  K+YT+
Sbjct: 362 LRDMKDTEILLDKNSKYYLDFT------KLQKSAKKYTI 394


>UniRef50_UPI00005A08B8 Cluster: PREDICTED: similar to USP6
           N-terminal like protein (Related to the N terminus of
           tre) (RN-tre); n=2; Canis lupus familiaris|Rep:
           PREDICTED: similar to USP6 N-terminal like protein
           (Related to the N terminus of tre) (RN-tre) - Canis
           familiaris
          Length = 616

 Score = 83.0 bits (196), Expect = 3e-14
 Identities = 48/162 (29%), Positives = 78/162 (48%), Gaps = 3/162 (1%)

Query: 274 REVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLEN 331
           +EVGYCQG   I   LLM +PEE+AF  L ++M   +H M   F P   +L       E 
Sbjct: 237 QEVGYCQGMSEIAATLLMFLPEEDAFWALAQLMTDDRHAMHGFFVPGFPKLLRFQAHHER 296

Query: 332 LVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVA 391
           +++  LPDL  H   +  ST +Y                L  ++ DV++ +G  ++  +A
Sbjct: 297 VLERALPDLRKHMDEEQMSTGIYTPKWFLQCFLGRTPFSLTLKLWDVYMLDGERVLTAMA 356

Query: 392 LALLTLGKNDLLSLDMESILKYIQKELPLK-AEADQAAFMNL 432
             +L + +  LL L +E + +++Q  L    A  D+A   +L
Sbjct: 357 YTILKVHRKRLLKLPLEGLREFLQDSLAQPWALKDEAVLRHL 398


>UniRef50_Q2GVF3 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 1082

 Score = 82.6 bits (195), Expect = 4e-14
 Identities = 65/221 (29%), Positives = 95/221 (42%), Gaps = 11/221 (4%)

Query: 192 RDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKV-----IRRDIARTYP 246
           R LV  GVP   R  +W    G +       YAS +    + +       I+ DI RT  
Sbjct: 746 RSLVLGGVPVASRSKIWSECCGANALRIPGYYASLMARPESSDDAQVVAQIKADITRTLT 805

Query: 247 EHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPE-EEAFAVLVKI 305
           ++ FF++  G G + L +V+ AYS  + +VGYCQG   +V  LL+  P  E+AF +L  +
Sbjct: 806 DNIFFRK--GPGVQKLHDVLLAYSRRNPDVGYCQGMNLVVANLLLITPSAEDAFWILCSM 863

Query: 306 MQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXX 365
           ++       F  S+         L   V ELLP L  HF   +                 
Sbjct: 864 VETILPPHYFDHSLLASRADQVVLRQYVAELLPKLSAHFDDLAIDLETMTFQWFLSLFTD 923

Query: 366 XXXXPLACRIMDVFLSEGIE---IVFKVALALLTLGKNDLL 403
                   R+ DV L   ++    +F+VALALL L +  LL
Sbjct: 924 CLSAEALFRVWDVVLCSPLDAAAFLFQVALALLKLNEAHLL 964


>UniRef50_O62462 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 1247

 Score = 82.2 bits (194), Expect = 6e-14
 Identities = 72/305 (23%), Positives = 126/305 (41%), Gaps = 19/305 (6%)

Query: 102 IPTPDRALLAKLEE--ENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETRP 159
           +P  DR +L+K+    E  +IE   + A   +   R                   +E  P
Sbjct: 392 VPDRDR-VLSKITVFLERGKIERTMEKAKADSERGRSSTSSSSSSFDKLIWDCPLIEKYP 450

Query: 160 TPGTNGEEDLWSLWGRLVSNWESE-WKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSP 218
             G +  +     W + +  + +     R   +  L+ +GVP   RG +W + +G   + 
Sbjct: 451 F-GADASDKCREKWNKYLQEYGTGVCMYRTVELHRLLLEGVPLQLRGQIWMVCSGA--AA 507

Query: 219 EKKLYASYIK--------AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYS 270
           E  L   Y +          S   + I RD+ R+ PEH  F++  G G ++L  ++ AY+
Sbjct: 508 EMALNPGYYRELLHKNQGVYSVALEEIERDLHRSLPEHPAFQQ--GPGIDALRRILTAYA 565

Query: 271 LHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLE 330
             +  +GYCQ    +  +LL+   EEEAF +LV + ++  + D +   +    +      
Sbjct: 566 FRNPNIGYCQAMNIVGSVLLLFTKEEEAFWLLVAVCER-LLPDYYNTKVVGALVDQGVFS 624

Query: 331 NLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKV 390
            LV+ LLP +            + A                A RI+D+F  EG  ++F+V
Sbjct: 625 ELVERLLPTVGAQLTRLGLD-DMVALSWFLTVFLSAIKFDAAVRILDLFFFEGARLMFQV 683

Query: 391 ALALL 395
           AL +L
Sbjct: 684 ALEML 688


>UniRef50_Q4CMS8 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 480

 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 10/234 (4%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDT--SPEKKLYASYIKAKSACE----KVIRRDIART 244
           +R + R G+P   R  +W   +G  T      ++Y   ++          + I +D+ RT
Sbjct: 212 LRCVYRYGLPQCLRSALWLEWSGGSTLLRESPRMYDELLERSDRVHGQPLQDILQDVVRT 271

Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVK 304
            P H FF +K G G E L NV+ A  L      Y Q   +IV  +L+ +P  EAF V+  
Sbjct: 272 APRHPFFAKKGG-GAEDLRNVLLALELACVLPSYHQAFSYIVATVLLNLPAREAFWVVTA 330

Query: 305 IMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXX 364
           +          +    +  L ++    +V    PD+HVHF S+S   S++A         
Sbjct: 331 LFSGFLPSGYHEHYTLQYDLQVY--NEIVAHKFPDVHVHFASKSIDVSVFASGWLQGLFC 388

Query: 365 XXXXXPLACRIMDVFLSEG-IEIVFKVALALLTLGKNDLLSLDMESILKYIQKE 417
                  A R++DV L+EG    + +  +A     ++++L++D    L Y   E
Sbjct: 389 AHFPFCTAARVLDVLLAEGDSSTLVRFLVAFTGKFRSEILTMDSSGSLGYFANE 442


>UniRef50_Q0UN04 Cluster: Putative uncharacterized protein; n=1;
            Phaeosphaeria nodorum|Rep: Putative uncharacterized
            protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 1240

 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 69/249 (27%), Positives = 103/249 (41%), Gaps = 9/249 (3%)

Query: 177  VSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKV 236
            + N  S  + + Q  R LV  G+P   R  VW   +G         Y   +        +
Sbjct: 783  LGNKGSVGRAKWQEFRRLVLGGIPVALRAKVWAECSGASALRVPGYYEDIVSNGEDDPTI 842

Query: 237  ---IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQM 293
               I+ DI RT  ++ FF+   G G + L  V+ AYS  + EVGYCQG   I   LL+ +
Sbjct: 843  ATQIQMDITRTLTDNIFFRT--GPGVQKLNEVLLAYSRRNPEVGYCQGMNLITACLLLIL 900

Query: 294  P-EEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTS 352
            P  E+AF VL  +++    ++ +   +         L + V ELLP L  H         
Sbjct: 901  PTAEDAFWVLATMIENILPQNYYDAHLLTSRADQSVLRSYVVELLPRLSAHLDELEIELE 960

Query: 353  LYAXXXXXXXXXXXXXXPLACRIMDVFL--SEGIEIVFKVALALLTLGKNDLLSLDMES- 409
                                 R+ DV L   +G   +F+VALALL L +  LL  D  + 
Sbjct: 961  ALTFQWFLSVFTDCLSAEALFRVWDVVLCMHDGSTFLFQVALALLKLNEKALLQCDTPAG 1020

Query: 410  ILKYIQKEL 418
            +  YI  ++
Sbjct: 1021 VYHYINHQM 1029


>UniRef50_UPI0000E4616F Cluster: PREDICTED: similar to mKIAA1055
            protein; n=1; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to mKIAA1055 protein -
            Strongylocentrotus purpuratus
          Length = 1076

 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 2/209 (0%)

Query: 262  LFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAE 321
            L  V+ AYS+H+  +GYCQG   +  + L+ + EE+AF  L+ I++     D +  ++  
Sbjct: 840  LRRVLLAYSVHNPAIGYCQGLNRVAAIALLYLEEEDAFWCLIAIVEYIMPMDYYSKTLIG 899

Query: 322  LGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLS 381
                      L+ E +P LH HF+  S   SL                    RI D FLS
Sbjct: 900  SQTDQRVFRELLAEKIPRLHSHFEEYSIDLSLVTFNWFVTCFCDNIPAETMLRIWDTFLS 959

Query: 382  EGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPK 441
            EG +++F+ +LA   + + +LL  +    +  + + +P +   D      +A+  ++NP 
Sbjct: 960  EGNKVLFRYSLAAFKIFEEELLKQNDYLRIFAVLRRMP-EMLTDVQKLTQIAFD-ELNPF 1017

Query: 442  KMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
              + +  + T+ +   +  +  L  +R E
Sbjct: 1018 PRRHINNKRTIHRAHVKQQLDELEAIRAE 1046


>UniRef50_A4HHG8 Cluster: GTPase activator protein, putative; n=3;
           Leishmania|Rep: GTPase activator protein, putative -
           Leishmania braziliensis
          Length = 586

 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 78/328 (23%), Positives = 140/328 (42%), Gaps = 23/328 (7%)

Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQ-GVPHHFRGIVWQLLAGVDTSPEKKLY-- 223
           ED W+   R VS   S        +R + R+ G+PHH R ++W  L G+    ++  Y  
Sbjct: 249 EDKWNRRCRGVSLLASASPDVIVKLRAVAREYGIPHHLRSVMWLTLTGMALKVDENEYFC 308

Query: 224 ------ASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVG 277
                   Y+   +A    I  D+ RT+P+H +F ++D +G   L NV+ A    +  + 
Sbjct: 309 AKLLRRNGYVTGSNA--DAIAADVQRTFPDHPYFSDQD-VGTYKLTNVLHALCWRNPLLS 365

Query: 278 YCQGSGFIVGLLLMQMPEEE-AFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
           YCQ   F+   LL+ + +EE AF +LV I ++    D +  ++    +    LE LV++ 
Sbjct: 366 YCQSFNFLAAFLLLVLDDEERAFWLLVHIFEELLPNDFYGETLLGANVEQAVLEYLVEKQ 425

Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMD-VFL---SEGIEIVFKVAL 392
           LP +   F+       +                     + D VF    S G      + +
Sbjct: 426 LPRVAAKFREAGLQVKVLVANWIMSLFVNVFPIETTLHVWDYVFCRTPSPGERTPAHLEI 485

Query: 393 ALLTLGKNDLLSL----DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEK 448
            L TL   D  SL    +   +L  ++K      +A+  A + LA S+ + P ++ +L +
Sbjct: 486 TLATLKYLDDASLLSSGNAGELLVSLRKHTACLFDAE--ALVRLAQSMTIAPAQLHQLRR 543

Query: 449 EYTVIKTKEQGDIAVLRCLRQENRLLKQ 476
           +      ++       R ++QE R+ ++
Sbjct: 544 QCKPAVVQQMKAREQARVVQQERRVAQE 571


>UniRef50_UPI00006CA417 Cluster: TBC domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: TBC domain containing
           protein - Tetrahymena thermophila SB210
          Length = 560

 Score = 79.8 bits (188), Expect = 3e-13
 Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 13/261 (4%)

Query: 204 RGIVW--QLLAGVDTSPEKKLYASYIKAKSACEKV---IRRDIARTYPEHDFFKEKDGLG 258
           + I W  Q     D    K+ Y S ++ K   ++    I  D  RTYP    F E   L 
Sbjct: 293 QAIAWLKQQYRNNDFQKMKEQYKSLLQMKEIYQQYKHQIDLDAVRTYPSSGLFHEGAPLC 352

Query: 259 QESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPS 318
           Q SL NV+ A+S++D +VGY QG  FIVGL+L    E  AF +   I +   MRD++ P 
Sbjct: 353 Q-SLKNVLYAFSVYDIQVGYVQGINFIVGLMLYHAEEYIAFWLTCMIFESLEMRDIYLPQ 411

Query: 319 MAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDV 378
           +  +    + +E L+ +  P +H  F                             + +D 
Sbjct: 412 LPGIKKHTYLIEFLMWKHTPYIHQIFFDNDIKIEQICQSWIISLCGILIPLDQMTQFVDK 471

Query: 379 FLSEGIEIVFKVALALLTLGKNDLLSLDM-ESILKYI-----QKELPLKAEADQ-AAFMN 431
            L EG    ++  +  +   ++D+L  ++ E ++  +     Q E   + E  Q    M 
Sbjct: 472 LLKEGWSFFYRFVITYILFHEDDILKQEVPEDVVALLTSQSYQLEFQTREEGIQWDQLMK 531

Query: 432 LAYSVKVNPKKMKKLEKEYTV 452
            A ++KVN   +++L +++ +
Sbjct: 532 SALNIKVNESIIRELHEKFDI 552


>UniRef50_Q4UF50 Cluster: GTPase activator, putative; n=3;
           Theileria|Rep: GTPase activator, putative - Theileria
           annulata
          Length = 589

 Score = 79.8 bits (188), Expect = 3e-13
 Identities = 67/239 (28%), Positives = 103/239 (43%), Gaps = 13/239 (5%)

Query: 186 RRNQWVRDLVRQGVPHHFRGIVW---QLLAGVDTSPEKKLYASYIKAKSACEKVIRRDIA 242
           R NQW     +  V    +G+ W   QLL        K+   S +         I  DI 
Sbjct: 112 RFNQWWLKCCQSAVLKQ-QGVYWNLIQLLGAKVVVNSKETSVSELVLGRRITLAIEMDIK 170

Query: 243 RTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVL 302
           RTYP   FF      G+  +  ++ AY+  D EVGY QG  FIV  LL    EE+AF  L
Sbjct: 171 RTYPSLRFFTR---YGRSMMRRILLAYAFFDTEVGYVQGLNFIVANLLWHSSEEQAFWAL 227

Query: 303 VKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS-----QSFSTSLYAXX 357
           + +M  + +R MF P +  +      LE+ + + +P LH H +S        ++  +   
Sbjct: 228 ISMMYLYDLRCMFLPGLPGVFKRCEILEHCMIKYIPKLHDHLKSVGVHIPMIASDWFMTL 287

Query: 358 XXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQ 415
                        L   + D F SEG   +F+  L  L   ++ L+++ D+  I+K I+
Sbjct: 288 CANSIPIKALVLSLPGLLWDCFFSEGWIAIFRFILYRLKQFEDYLVTMSDIADIMKVIK 346


>UniRef50_A2DSN7 Cluster: TBC domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: TBC domain containing
           protein - Trichomonas vaginalis G3
          Length = 354

 Score = 79.8 bits (188), Expect = 3e-13
 Identities = 61/261 (23%), Positives = 107/261 (40%), Gaps = 10/261 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD-----TSPEKKLYASYI 227
           W ++ +NW     +  + + + +R G+P   R   W+++   D           L +   
Sbjct: 65  WMKMYNNWIYYSGKGREKLCEFIRHGIPDSCRERAWKIILQPDFLNPLADTSVDLDSLIN 124

Query: 228 KAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
           K  ++  + I  D+ RT P    F     L   SL  ++KAYS  D E+GY QG  FI  
Sbjct: 125 KGATSVWRTIEADLDRTMPNCPMFYNDKCLN--SLRRILKAYSNQDPELGYTQGMSFIAA 182

Query: 288 LLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
           +LL+ + E  A+    K+M  ++H +R+ F P        +   + + +   P +H H  
Sbjct: 183 MLLLYLDENTAYNCFAKLMSGEKHLLRNHFLPGFPRYKEILKIWDVVFRAKYPKVHEHLL 242

Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXP-LACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
             +  ++ Y               P +   I D ++  G   +   AL +++  K  L+S
Sbjct: 243 RLNCDSNFYTPSWFLTGFLNVEFPPIIRLHIFDCWIEFGSRALLSFALVIISRNKKALVS 302

Query: 405 LDMESILKYIQKELPLKAEAD 425
              E IL  +Q    L    D
Sbjct: 303 DPFELILPNLQNPQNLPTMQD 323


>UniRef50_A6RXA8 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 1048

 Score = 79.8 bits (188), Expect = 3e-13
 Identities = 68/243 (27%), Positives = 104/243 (42%), Gaps = 13/243 (5%)

Query: 187 RNQW--VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI-KAKSACEKV----IRR 239
           R +W   ++LV  G+P  +R  +W   +G         Y   I +++   + V    I+ 
Sbjct: 708 RAKWNEFKNLVLGGIPVAYRAKIWAECSGASAMRIPGYYDDLIARSEEDDDPVVVAQIQM 767

Query: 240 DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMP-EEEA 298
           DI RT  ++ +F++  G G   L  V+ AYS  + EVGYCQG   I   LL+ MP  E+A
Sbjct: 768 DINRTLTDNIYFRK--GPGVAKLNEVLLAYSRRNHEVGYCQGMNLITACLLLIMPTAEDA 825

Query: 299 FAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXX 358
           F VL  I++       +  S+         L   V E+LP L  H               
Sbjct: 826 FWVLTSIIEHTLPPGYYDHSLLASRADQQVLRQYVSEILPKLSQHLDDLCIELEALTFQW 885

Query: 359 XXXXXXXXXXXPLACRIMDVFL--SEGIEIVFKVALALLTLGKNDLLSLDM-ESILKYIQ 415
                          R+ DV L  ++G   +F+VALALL L +  LL      ++  YI 
Sbjct: 886 FLSVFTDCLSAEALFRVWDVVLCMNDGSTFLFQVALALLKLNEQQLLQCSSPANVYTYIN 945

Query: 416 KEL 418
            ++
Sbjct: 946 HQM 948


>UniRef50_Q12317 Cluster: GTPase-activating protein MSB4; n=2;
           Saccharomyces cerevisiae|Rep: GTPase-activating protein
           MSB4 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 492

 Score = 79.8 bits (188), Expect = 3e-13
 Identities = 54/174 (31%), Positives = 90/174 (51%), Gaps = 16/174 (9%)

Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEK---------VI 237
           R   +   VR+G+P  +RG  W   AG     +  +   Y + KS C +          I
Sbjct: 136 RTDELSKFVRKGIPAEWRGNAWWYFAGGQRQLDANV-GVYDRLKSDCREGAVSGKDMEAI 194

Query: 238 RRDIARTYPEH-DFFKEKDGLGQ----ESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQ 292
            RD+ RT+P++  F KE    G+     SL  V+ A+S++D+ +GYCQ   F+VGLLL+ 
Sbjct: 195 ERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTIGYCQSMNFLVGLLLLF 254

Query: 293 MPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
           M EE+AF +LV I  ++ +  +++  +    +    L   ++E LP++  H +S
Sbjct: 255 MEEEKAFWMLVIITGKY-LPGVYESDLEGANVDQGVLVLCIKEYLPEIWSHIES 307


>UniRef50_Q4S8R1 Cluster: Chromosome 7 SCAF14703, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 7 SCAF14703, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1060

 Score = 79.4 bits (187), Expect = 4e-13
 Identities = 66/245 (26%), Positives = 112/245 (45%), Gaps = 35/245 (14%)

Query: 192 RDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAKSACEKV----IRRDIARTY 245
           RDL+ +GVP   RG +W L +G   D +     Y+  ++       +    I RD+ R+ 
Sbjct: 447 RDLIVRGVPEALRGELWMLFSGAVNDMATHPGYYSELVEQSLGTSTLATDEIERDLHRSL 506

Query: 246 PEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKI 305
           PEH  F+   G+   +L  V+ AY+  + ++GYCQ    +  +LL+   EEEAF +LV +
Sbjct: 507 PEHPAFQSDTGIS--ALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAV 564

Query: 306 MQQ------------HRMRDM-----------FKPSMA-ELGLCMFQ--LENLVQELLPD 339
            ++             + R+            FKP +   LG  + Q   E+L++E LP 
Sbjct: 565 CERMLPDYFNRRIIGEKRRESVVSLTVSVLAHFKPLLRFSLGALVDQAVFEDLIREHLPQ 624

Query: 340 LHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGK 399
           L  H    SF +S+ +                A  ++D F  +GI+ + ++ LA+L    
Sbjct: 625 LVEHMTDLSFFSSV-SLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAVLDYNM 683

Query: 400 NDLLS 404
           + L+S
Sbjct: 684 DALIS 688


>UniRef50_A0D1G2 Cluster: Chromosome undetermined scaffold_34, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_34,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 420

 Score = 79.4 bits (187), Expect = 4e-13
 Identities = 66/272 (24%), Positives = 122/272 (44%), Gaps = 12/272 (4%)

Query: 188 NQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKV---IRRDIART 244
           N+  ++++  G    +R   W      +   +  LY   +K ++  +KV   I +D+ RT
Sbjct: 146 NEDFKNILMDGAISKYRWNFWMAQVYRNQDYDPLLYQK-LKNETPSQKVLEDITKDVNRT 204

Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG--LLLMQMPEEEAFAVL 302
           +P HD FK+ +  GQ+ L +V+KA S+ + ++GY QG  +IVG  L++    EEE F ++
Sbjct: 205 FPSHDHFKDNNQ-GQQQLLSVLKALSILNEDIGYVQGMNYIVGFSLIVSGGKEEEVFWLI 263

Query: 303 --VKIMQQHRMRDMFKPSM-AELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
             +         ++++ +      LC   L+N  ++ LP L+ HFQ +  S   Y     
Sbjct: 264 HFINTNPLFFWWEIYRVNFNYTKALCQVFLKNFYEQ-LPGLYQHFQDEGISEQQYIWQWI 322

Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELP 419
                            D  L+  I  + ++++A L     DL++ D+  I +Y    + 
Sbjct: 323 LTQFLYTFPIDNVIFFWDFILATDIFSIIRISIAFLKEYGFDLVNKDIGEISEYFTGFIK 382

Query: 420 LKAEADQAAFMNLAYSVKVN-PKKMKKLEKEY 450
            + + D    +  A  + VN     K+  K Y
Sbjct: 383 DQLQIDIPQIIEAAKKIDVNMTDDQKQFFKNY 414


>UniRef50_Q0DSW7 Cluster: Os03g0283800 protein; n=7;
           Magnoliophyta|Rep: Os03g0283800 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 883

 Score = 79.0 bits (186), Expect = 5e-13
 Identities = 72/245 (29%), Positives = 102/245 (41%), Gaps = 31/245 (12%)

Query: 179 NWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------------------DTS 217
           N ES +  R + +  LVR GVP   RG +WQ   GV                     + +
Sbjct: 305 NGESYFPWREE-LESLVRGGVPMALRGEMWQAFVGVGARKITGYYNKLLDEGTEELDEKN 363

Query: 218 PEKKLYASYIKA-KSACEK---VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHD 273
           PE +       A K   EK    I +D+ RT+P H    E    G+ +L  ++ AY+ H+
Sbjct: 364 PEDQELKDQTNAQKKPPEKWKGQIEKDLPRTFPGHPALDED---GRNALRRLLTAYARHN 420

Query: 274 REVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLV 333
             VGYCQ   F  GL L+ MPEE AF  LV ++ ++     +   M E  +    LE +V
Sbjct: 421 PSVGYCQAMNFFAGLFLLFMPEEHAFWALVGVIDEY-FDGYYTEEMIESQVDQLVLEEVV 479

Query: 334 QELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIE-IVFKVAL 392
           +E  P L  H        +                     R+ DV L EG   ++F+  L
Sbjct: 480 RERFPKLAKHMDFLGVQVAWVTGPWFLSIFINMLPWESVLRVWDVILFEGNRTMLFRTTL 539

Query: 393 ALLTL 397
           ALL L
Sbjct: 540 ALLDL 544



 Score = 35.5 bits (78), Expect = 6.4
 Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 12/114 (10%)

Query: 689 DMLKLDEE-LMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
           +M+K D   +++ ++ ++EA  E+ ELR    + + Q Q     L R ++E ++     D
Sbjct: 716 EMVKQDNRHMLSAKVEKLEA--EVSELRKSFADKQEQEQAMLQVLIRMEQEQKVAE---D 770

Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSE 801
           A +  ER    +      KYA    + KY++  A +R ME    +AE   E ++
Sbjct: 771 ARIAAERDAADK------KYAAQLLQEKYDAAMAALRQMEKRAVMAETMLEATK 818


>UniRef50_A2FGC2 Cluster: TBC domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: TBC domain containing
           protein - Trichomonas vaginalis G3
          Length = 345

 Score = 79.0 bits (186), Expect = 5e-13
 Identities = 66/289 (22%), Positives = 126/289 (43%), Gaps = 23/289 (7%)

Query: 182 SEWKRRNQWVRDLVRQGVPHHFRGIVW----QLLAGVDTSPE--KKLYASYIKAKSACEK 235
           S +K  ++  +  +R+G+P   R ++W    +L   +D       +  + +       ++
Sbjct: 49  SHFKLDDKKFKKQIRKGIPMEVRPLIWAKITKLYEIMDARANIWDEAPSKFNTIHEDVKR 108

Query: 236 VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPE 295
            I  DI RT+P +  F        E L  ++  +++   E+GYCQ   F+  + L  M  
Sbjct: 109 TIDVDIPRTFPRNKAFSS------EYLKKILYVFAVAHPEIGYCQSLNFVAAICLFVMKS 162

Query: 296 E-EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLY 354
           + +AF +L+ I++ +  +  F P M +    +  L+ L+ E  P++    ++ ++  +  
Sbjct: 163 DIQAFYLLLIIVENYLPKGYFTPDMKDYQTDICMLQILINERQPEVAAIAKAANYQWAQC 222

Query: 355 AXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL----DMESI 410
                              RI D F  EG +++F+VALA+L +  NDLL      D   +
Sbjct: 223 TSNWILTLFSNTLPVSTVMRIWDSFFLEGQKVIFRVALAILKI-NNDLLKAAKPSDFTKV 281

Query: 411 LKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQG 459
           LK +Q  +      DQ   M  A+ +K   +   K  +E  V   ++ G
Sbjct: 282 LKTVQGSI-----VDQEQLMTTAFGLKAFSRAHLKALREKAVELVEKSG 325


>UniRef50_Q4PEJ4 Cluster: Putative uncharacterized protein; n=1;
            Ustilago maydis|Rep: Putative uncharacterized protein -
            Ustilago maydis (Smut fungus)
          Length = 1447

 Score = 79.0 bits (186), Expect = 5e-13
 Identities = 59/216 (27%), Positives = 95/216 (43%), Gaps = 6/216 (2%)

Query: 194  LVRQGVPHHFRGIVWQLLAGVDTSPE----KKLYASYIKAKSACEKVIRRDIARTYPEHD 249
            L + G+P  +R  +W   +G +   E    ++L + +    + C   I  D+ RT P + 
Sbjct: 1166 LCQSGIPLCYRARIWAECSGANDVAEPGRYQELLSDHQGETNDCLTQIDLDVHRTMPTNV 1225

Query: 250  FFKEKDGLGQESLFNVMKAYSLHDREVGYCQG-SGFIVGLLLMQMPEEEAFAVLVKIMQQ 308
            +F   DG G   L  ++ A+S ++   GYCQG +     LLL    EEEAF VLV ++++
Sbjct: 1226 YFGG-DGQGVPKLRRLLVAFSWYNPSTGYCQGMNNLAATLLLTHATEEEAFWVLVCLIEK 1284

Query: 309  HRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXX 368
                + +   +         L  LV E +P LH H                         
Sbjct: 1285 ILPSEYYTSHLLVSQADQRVLIELVSEHMPALHAHMAQLGVDLPAITFAWFLSLYTDCLP 1344

Query: 369  XPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
                 R+ DV   EG+ I+F+VA+A+L L +  LL+
Sbjct: 1345 VETLFRVWDVMFVEGMVILFRVAMAILKLYEKQLLA 1380


>UniRef50_Q22P21 Cluster: TBC domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: TBC domain containing
           protein - Tetrahymena thermophila SB210
          Length = 583

 Score = 78.6 bits (185), Expect = 7e-13
 Identities = 54/197 (27%), Positives = 97/197 (49%), Gaps = 17/197 (8%)

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
           I +DI RT+PE  FF++K  +GQ+ L   + A S   R+VGYCQG  FI+G+LL+    +
Sbjct: 289 IVKDITRTFPEIKFFEDKQ-MGQDQLKRTLMATSNLFRKVGYCQGMNFIMGMLLLVSGGD 347

Query: 297 EAFA----VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTS 352
           E+      + +    ++ +  +F+     L    +  E+L +  L +L++HF+ Q    +
Sbjct: 348 ESSVFDCFISLSFRPEYMLVGLFENGFPLLRFLEYVFEDLFKTHLNELYLHFKDQEIVNT 407

Query: 353 LYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILK 412
           ++                   RIMD  +S  I  +  VAL +L   K  LL +D   ++ 
Sbjct: 408 IWLTKWLMTK---------CIRIMDYVISTNIFALIYVALEILVQYKEQLLKMDNMDMIH 458

Query: 413 YIQKELPLKAEADQAAF 429
           +  K++    + D+++F
Sbjct: 459 FFSKKM---CKVDESSF 472


>UniRef50_A0EBU5 Cluster: Chromosome undetermined scaffold_88, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_88,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 496

 Score = 78.6 bits (185), Expect = 7e-13
 Identities = 58/248 (23%), Positives = 110/248 (44%), Gaps = 10/248 (4%)

Query: 185 KRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA-------KSACEKVI 237
           K  N  +RDL+R   P   RG +W  L G      K+LY   + +        +  + +I
Sbjct: 223 KAINGKLRDLLRNSYPEQHRGKIWSFLIGNQLQINKQLYEKLLLSIPNHPLITNELKNLI 282

Query: 238 RRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE 297
             D+ RT+   + F+  D L ++ L  ++  + ++  ++GY QG  ++  + L++MP+++
Sbjct: 283 NNDLQRTFTIINDFENSDKL-KDDLREILTIFHIYRPDMGYIQGMTYLAFMFLIRMPKQK 341

Query: 298 AFAVLVKIM-QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAX 356
           A   L  I+ +   +R  ++     L       ++  QE LP L   F   +     +  
Sbjct: 342 ALKCLANILFKSQLLRTFYQFKSHYLEAYFLLFDSFFQEKLPVLANKFNQINLPKQSFLV 401

Query: 357 XXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYI-Q 415
                          + ++ D FL EG   + ++ LA+L+  + +LL  + E IL  I Q
Sbjct: 402 EWFYTVFSRAFNLITSSKVWDYFLCEGDLFLIRLTLAVLSNLEPELLKCEYEDILMLIRQ 461

Query: 416 KELPLKAE 423
           K   +K +
Sbjct: 462 KTYQIKID 469


>UniRef50_A0CVA1 Cluster: Chromosome undetermined scaffold_29, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_29,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 949

 Score = 78.6 bits (185), Expect = 7e-13
 Identities = 62/247 (25%), Positives = 117/247 (47%), Gaps = 22/247 (8%)

Query: 234 EKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQM 293
           E+ I+ D+ R+   H   KEK  +    L ++++ Y+ +++EVGYCQG  +I G L +  
Sbjct: 697 EETIKLDVQRSLHLH---KEK--INSSVLQSLLRIYAFYNQEVGYCQGMNYIAGYLYLTF 751

Query: 294 PEE-EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTS 352
            ++  A+    ++M  +  +D++    ++L +  +Q + L+Q  LP+L  H + Q    S
Sbjct: 752 QDQVTAYKAFDRMMNLY-FKDLYINDFSKLKIGFYQFDRLLQVFLPELSQHLKDQKIDPS 810

Query: 353 LYAX----XXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
            Y                    L   I D+FL+E  +  FKV   LL L +  +L L+ +
Sbjct: 811 YYVASWFITLYSNVFQFSQRSALLNIIWDIFLAEEWKGFFKVTFYLLWLLQQKILDLEFD 870

Query: 409 SILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLR 468
            IL Y+ +   +K+E     F  +   +++    +K ++     +K  E     +L+  R
Sbjct: 871 DILHYLGQ--LIKSE-----FFTIDNEIEL----IKLVQNYDKTVKENESIKTTILQKFR 919

Query: 469 QENRLLK 475
             NR+L+
Sbjct: 920 VTNRMLR 926


>UniRef50_Q5KC17 Cluster: Rab GTPase activator, putative; n=2;
            Filobasidiella neoformans|Rep: Rab GTPase activator,
            putative - Cryptococcus neoformans (Filobasidiella
            neoformans)
          Length = 1137

 Score = 78.2 bits (184), Expect = 9e-13
 Identities = 68/261 (26%), Positives = 115/261 (44%), Gaps = 8/261 (3%)

Query: 191  VRDLVRQ-GVPHHFRGIVWQ-LLAGVDTSPEKKLYASYIKA-KSACEKVIRRDIARTYPE 247
            VR LV + G+P+  RG VW   +A    +    LY   ++  K   ++ I +D+   YP+
Sbjct: 863  VRKLVLEAGIPNSLRGKVWAWFMAKALLARVPGLYHELLEHDKRPEDERIEQDVLAAYPD 922

Query: 248  HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
            H  F E +  GQ+ L  +++AYS H    GY      I G LL+    E++F +L  ++ 
Sbjct: 923  HSIFAESNCPGQQDLRYILRAYS-HFAPDGYRPEMALIAGALLIHCVAEDSFWLLSGLVN 981

Query: 308  QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
               ++D +      L +     E L+    P L   F+        +             
Sbjct: 982  S-VLKDFYGKEKVGLKIEAGVFEKLLSSAEPKLAKLFKEIGLQPVEFLGKWFGQLFIRCL 1040

Query: 368  XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL--DMESILKYIQKELPLKAEAD 425
              P A R++D  + EG   +   +LA+L+L ++ LL L  + + IL Y+   LP  +   
Sbjct: 1041 PWPTALRVIDAVVCEGTRFLLVASLAVLSLSRDRLLRLPPNHDIILNYLH-NLPQDSLLL 1099

Query: 426  QAAFMNLAYSVKVNPKKMKKL 446
             A FM     +K   K+ +K+
Sbjct: 1100 PAHFMKACEEIKFEEKEYRKI 1120


>UniRef50_A3LRK5 Cluster: Predicted protein; n=3;
           Saccharomycetaceae|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 558

 Score = 78.2 bits (184), Expect = 9e-13
 Identities = 60/223 (26%), Positives = 109/223 (48%), Gaps = 13/223 (5%)

Query: 195 VRQGVPHHFRGIVWQ--LLAGVDTSPE--KKLYASYIKAKSACEKV-IRRDIARTYPEHD 249
           +RQG+P+  R  +WQ  LL    + P+  K ++ ++  + SA   V I +D+ RT+P  +
Sbjct: 133 LRQGIPNQIRSTIWQKLLLLNHTSIPQTTKLIFRNFQHSYSAEISVQISKDLNRTFPTVN 192

Query: 250 FFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQM--PEEEAFAVLVKIMQ 307
           FF+ ++ +  + L  ++  Y+ +D E+GYCQG  F+VG+L  Q     E     L+ IM+
Sbjct: 193 FFRSQEAI--DGLLTILNVYANYDAELGYCQGLLFLVGVLYYQFKGDAEMTLHALITIME 250

Query: 308 -QHRMRDMFKPS--MAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXX 364
            +  + D+F  S   + L     +   +++E    L+ H        S            
Sbjct: 251 SETELHDIFTTSSMCSTLNKWYGEFLYILKETDEKLYDHLTGFVELQSFLFQWWLSFISS 310

Query: 365 XXXXXPLACRIMDVFLSEGIEI-VFKVALALLTLGKNDLLSLD 406
                 +  ++MD  + EG ++ +FK++L LL   K  L++LD
Sbjct: 311 HSPDLSIVNKVMDFCMLEGWKVGLFKISLGLLVSNKPILMTLD 353


>UniRef50_Q4T9M9 Cluster: Chromosome undetermined SCAF7533, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF7533, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 646

 Score = 77.8 bits (183), Expect = 1e-12
 Identities = 80/344 (23%), Positives = 139/344 (40%), Gaps = 37/344 (10%)

Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTS------PE 219
           E  L   W   ++   ++  R +  ++ L+R GVP  +R  +W  +  V T       P+
Sbjct: 290 ERPLLERWAHFLAARSAQDLRASPELKGLLRGGVPQEYRRQLWTWMVHVRTGSIREQEPD 349

Query: 220 --KKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVG 277
             ++L      +     + I  D+ RT   +  F        + L  ++ A+S  +  +G
Sbjct: 350 GYQQLCQKSGTSPHPASRQIELDLPRTLTTNQLFSSPSSAALQQLRRILLAFSWRNPAIG 409

Query: 278 YCQG---------------SGFI---------VGLLLMQMPEEEAFAVLVKIMQQHRMRD 313
           YCQG               SG +         V LL++Q  EEEAF  LV I++    +D
Sbjct: 410 YCQGLNRCWALAAACAGGRSGDLRCAAPRLAAVALLVLQS-EEEAFWCLVAIVETIMPQD 468

Query: 314 MFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLAC 373
            +  ++         L++ + E LP +  HF SQ    SL                 +  
Sbjct: 469 YYTQNLVASQADQRVLKDFLSEKLPRISAHFASQGVDVSLVTFNWFLVVFVESLPSDILL 528

Query: 374 RIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLA 433
            + D FL EG +++F+ ALAL    ++D+L +   S+  Y       K   D     N+A
Sbjct: 529 PLWDAFLYEGTKVIFRYALALFKYKEDDILKIH-SSVELYQYLRFFTKTITDTRRLSNMA 587

Query: 434 YSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQR 477
           +   +NP   + L     +   + QG++   R  +Q+   L +R
Sbjct: 588 FG-DMNPFPGRLLRSRRALHLERLQGELQ--RLAQQQEAFLAER 628


>UniRef50_A7AUV6 Cluster: TBC domain containing protein; n=1;
           Babesia bovis|Rep: TBC domain containing protein -
           Babesia bovis
          Length = 463

 Score = 77.8 bits (183), Expect = 1e-12
 Identities = 66/250 (26%), Positives = 106/250 (42%), Gaps = 7/250 (2%)

Query: 205 GIVWQLLAGVD---TSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQES 261
           G+ W L+  +D   T    K+  + I         I  DI RTYP   F+      G+  
Sbjct: 62  GVYWNLVEYLDEKVTIDGVKMTVADIVLGQKTTTAIMLDIRRTYPSLRFYTR---YGRIM 118

Query: 262 LFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAE 321
           L  ++ AY+  D EVGY QG  FIV  LL    EE+AF   + +M  +  R MF   +  
Sbjct: 119 LRRILLAYAFFDPEVGYVQGLNFIVANLLWHSTEEQAFWSFLSMMYMYDCRCMFLQGLPG 178

Query: 322 LGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLS 381
           +      +E  +Q+ +P L  H ++      + A                  R+ D F +
Sbjct: 179 VFKRCDIIEKCMQDHVPKLTEHLRNVGVHIPMIASDWLMTLCANSIPIKPLARLWDSFFA 238

Query: 382 EGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNP 440
           EG  ++F+  L  L   +  LL++ D+  I+K I+     KAE+     +   +   +  
Sbjct: 239 EGWIVIFRFVLCRLKQFEPYLLTINDVADIMKVIKYGHAQKAESWNFIELIPGFGQTLEN 298

Query: 441 KKMKKLEKEY 450
           K +K +E  Y
Sbjct: 299 KGVKLVEDAY 308


>UniRef50_Q4P6P1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 1357

 Score = 77.8 bits (183), Expect = 1e-12
 Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)

Query: 240 DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAF 299
           D+ RT   H  F  + G GQ +LF+V+ A S+   + GYCQG G I   LL     E A+
Sbjct: 439 DVPRTISGHIQFHTRYGQGQRALFHVLHAMSMLCDQCGYCQGMGPIAATLLCYFSPERAY 498

Query: 300 AVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
           A +  +     +   F P    L   +F  + L+++ +P+L   F  Q   +S YA    
Sbjct: 499 AAMTMMHNHLNLHSTFAPGFPGLVENLFVQDQLLRKYMPELVEVFDEQMVVSSSYATKWF 558

Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL--SLDMESIL 411
                         R+ D +L +G +++  VAL ++   +  +L    D E+IL
Sbjct: 559 ITLFSNSIPFETQLRVWDAWLLDGQDVISLVALGIIWAHRGVILEPDADFETIL 612


>UniRef50_A2EC67 Cluster: TBC domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: TBC domain containing
           protein - Trichomonas vaginalis G3
          Length = 292

 Score = 77.4 bits (182), Expect = 2e-12
 Identities = 62/269 (23%), Positives = 110/269 (40%), Gaps = 9/269 (3%)

Query: 176 LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEK 235
           ++S+W+    + +  +R+ +++G+P   R   W  L       +        K      +
Sbjct: 1   MLSHWDEFTGKHHNKLRERIKKGIPDSLRSRAWPKLIIPHYGTQDYHPTDVDKLLEGGNQ 60

Query: 236 V----IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM 291
           V    I +D+ART P +  F  +      SL  V+ AYS  D E+GY QG   I GLLL+
Sbjct: 61  VGYQTIEKDLARTMPNYPMFNNEKVFN--SLRRVLYAYSNKDPELGYTQGMSAIAGLLLL 118

Query: 292 QMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSF 349
            + E  A+     +M  +++ +R  F      L L     E +++E  P +   F   + 
Sbjct: 119 YLDESTAYDCFETLMLDERYGLRHYFIQEFPRLKLLNKVWEEIMKERYPKVWKTFTKVNL 178

Query: 350 STSLYAXXXXXXXXXXXXXXP-LACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
            +  Y               P L  RI D F   G + +    L +++  K+DL++   E
Sbjct: 179 ESLYYTPSWFLTLFFNQKIAPILKFRIFDRFCEFGSKALISFGLVIVSRHKDDLINKPFE 238

Query: 409 SILKYIQKELPLKAEADQAAFMNLAYSVK 437
            ++  +Q      +  D     +  Y +K
Sbjct: 239 KVIMTMQHPFKRGSSEDSGKMDDWRYVLK 267


>UniRef50_UPI00005A1247 Cluster: PREDICTED: similar to USP6
           N-terminal like protein (Related to the N terminus of
           tre) (RN-tre); n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to USP6 N-terminal like protein
           (Related to the N terminus of tre) (RN-tre) - Canis
           familiaris
          Length = 502

 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 2/147 (1%)

Query: 274 REVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLEN 331
           +EVGYCQG   I   LLM +PEE+AF  L ++M   +H M   F P   +L       E+
Sbjct: 249 QEVGYCQGMTEIAATLLMFLPEEDAFWALAQLMTDDRHAMHSFFVPGFQKLLRFQAHHEH 308

Query: 332 LVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVA 391
           +++  LP L  H   +  ST +Y                L  ++ D ++ +G  ++  +A
Sbjct: 309 VLERALPYLRKHVDEEQMSTGIYTPKWFLQCFLGRTPFSLTLKLWDAYILDGERVLTAMA 368

Query: 392 LALLTLGKNDLLSLDMESILKYIQKEL 418
             +L + +  LL L +E + +++Q  L
Sbjct: 369 YTILKVHRKRLLKLPLEGLREFLQDSL 395


>UniRef50_Q94222 Cluster: Putative uncharacterized protein; n=3;
           Bilateria|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 826

 Score = 75.4 bits (177), Expect = 6e-12
 Identities = 52/216 (24%), Positives = 98/216 (45%), Gaps = 10/216 (4%)

Query: 198 GVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEK-------VIRRDIARTYPEHDF 250
           G+PH  R  +W  L+G  T  +K    +Y      C +        I RD+ RT P +  
Sbjct: 150 GIPHSMRPFLWPRLSGA-TKKQKDAKYTYESVLQQCAQDKPSIGVQIERDLLRTLPNNIC 208

Query: 251 FKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHR 310
           F +K+  G E+L  ++K  +    ++GYCQG G IV  LL+   EE  F ++  +++   
Sbjct: 209 FWKKNSEGIEALRRILKCVAFIYPDLGYCQGMGVIVATLLLYCSEETTFWMMTALIEDIL 268

Query: 311 MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXP 370
             + +  ++  L        +L++  +PDL+   +      SL                 
Sbjct: 269 PPNFYTQTLLGLQADERVSRHLMKCHVPDLNKALEDYEVEVSLLTVSWLLTLFGSVFRTR 328

Query: 371 LACRIMD-VFLSEGIEIVFKVALALLTLGKNDLLSL 405
           +  R+ D +F S G+ I F+V +++L + + +++ +
Sbjct: 329 VMLRVWDFIFYSGGVNI-FRVIISILKMKEQEIVEI 363


>UniRef50_Q5CTF9 Cluster: Tbc domain-containing protein; n=2;
           Cryptosporidium|Rep: Tbc domain-containing protein -
           Cryptosporidium parvum Iowa II
          Length = 678

 Score = 75.4 bits (177), Expect = 6e-12
 Identities = 54/185 (29%), Positives = 86/185 (46%), Gaps = 5/185 (2%)

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM-QMPE 295
           I  D+ RTYP   +FK +   G+  L  ++  YSL D +VGY QG  F+VG +L     E
Sbjct: 165 IYMDVCRTYPSISYFKFE---GKSYLSKILLIYSLMDIDVGYVQGMNFLVGCILWHSSSE 221

Query: 296 EEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
           E+AF +LV +M  + MR+MF   +  L +    L  L+++ L  +  H   Q  +  + A
Sbjct: 222 EQAFELLVSLMFNYGMREMFVSGLPGLRVKCLILNQLMEKELHIIWDHIIRQGGTIDMLA 281

Query: 356 XXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL-ALLTLGKNDLLSLDMESILKYI 414
                          +  +  D F  +G   ++K+ L  L  +  N L S D+  I+  I
Sbjct: 282 TDWFLTLFSYSIPLNIIGKFWDDFFQQGWVPLYKLILYRLQRIESNILYSNDIADIMNAI 341

Query: 415 QKELP 419
           +   P
Sbjct: 342 KYSTP 346


>UniRef50_Q9BYX2 Cluster: TBC1 domain family member 2; n=36;
           Euteleostomi|Rep: TBC1 domain family member 2 - Homo
           sapiens (Human)
          Length = 917

 Score = 75.4 bits (177), Expect = 6e-12
 Identities = 71/287 (24%), Positives = 121/287 (42%), Gaps = 20/287 (6%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
           ++ L+R GVP   R  VW+ L    V        Y   +    A E    + I  D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677

Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
           +P +  F        + L  V+ A+S  +  +GYCQG   +  + L+ + EEE AF  LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737

Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
            I++     D +  ++    +    L++L+ E LP L  H        SL          
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797

Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
                  +  R+ D FL EG +   K  L L          L++   L++  K +     
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKYNEKEILRLQN-------GLEIYQYLRFFTKTI----- 845

Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
           ++    MN+A++  +NP +MK+L +   V + + + ++  L  L+ E
Sbjct: 846 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 891


>UniRef50_A2ELI1 Cluster: TBC domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: TBC domain containing
           protein - Trichomonas vaginalis G3
          Length = 331

 Score = 74.9 bits (176), Expect = 9e-12
 Identities = 61/284 (21%), Positives = 114/284 (40%), Gaps = 10/284 (3%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLL----AGVDTSPEKKLYASYIK 228
           W  + SNWE     +   V   +R+G+P  FR   W LL    A ++ +PE  +     K
Sbjct: 42  WAEMTSNWEYWITHKRDKVARRIRKGIPDSFRAKAWDLLTNAEASLNAAPE-NIEQLMQK 100

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
            +    K I  D+ RT+    +F   +   Q+SL  V+ +++  + E+GY  G   +   
Sbjct: 101 PELPTYKSIEADVQRTFTHTAYFSNPE--MQQSLRKVLCSFAQINPELGYVFGMSNLAAT 158

Query: 289 LLMQMPEEEAFAVLVKIMQQHRM--RDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
            LM + E         ++   R   +D F        L    L+ ++++ LP +H HFQ 
Sbjct: 159 FLMYLDENTTLWAFYNVLTGFRTLHKDYFTTGTPRWKLANQMLDIVLKDKLPKIHKHFQD 218

Query: 347 QSFS-TSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
            +     + A                  RI D+FL  G   +   A+++  + +++L++ 
Sbjct: 219 INLDLKQITAKWFIPAFLSYEWPSEFMLRIFDIFLFYGTRALLVFAISIFWVHRDELITD 278

Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKE 449
            +  ++  +          D   F+     + +N K    L K+
Sbjct: 279 SLADVITLMDNLDSSSKLKDWRVFLKNFDDLWINKKYYLSLLKQ 322


>UniRef50_Q6CGJ8 Cluster: Similar to DEHA0D17149g Debaryomyces
           hansenii IPF 2883.1; n=1; Yarrowia lipolytica|Rep:
           Similar to DEHA0D17149g Debaryomyces hansenii IPF 2883.1
           - Yarrowia lipolytica (Candida lipolytica)
          Length = 734

 Score = 74.9 bits (176), Expect = 9e-12
 Identities = 64/226 (28%), Positives = 94/226 (41%), Gaps = 16/226 (7%)

Query: 194 LVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--KAKSACE---------KVIRRDIA 242
           LV  G+P   R  +W   +G ++     LY   +     SA +           I  D+ 
Sbjct: 464 LVLGGIPVKLRPQIWSQCSGAESITIPGLYQELLTDSNSSATDYDPIAAQNTSQIDLDLY 523

Query: 243 RTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMP-EEEAFAV 301
           RT P + FF +  G G   L NV+ A S H+ + GYCQG   +  +LL+  P EE+AF  
Sbjct: 524 RTMPHNIFFGK--GPGVAKLRNVLVAVSRHNPDTGYCQGMNIMAAVLLLAFPTEEDAFWA 581

Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
           LV +       D   P +         L++ + + LP ++ H                  
Sbjct: 582 LVALTNL-LPTDYLAPPLLTSRADQRVLKSYIVQHLPQINQHMDQLEIDLEAITFSWFLS 640

Query: 362 XXXXXXXXPLACRIMDVFLS-EGIEIVFKVALALLTLGKNDLLSLD 406
                    +  RI DVFL  EG+  +FK ALAL  + K+ LL  D
Sbjct: 641 CFADTLPPEVLFRIWDVFLCLEGMSFLFKTALALFKMHKSQLLEFD 686


>UniRef50_UPI0000F33224 Cluster: TBC1 domain family member 1
            (Lyncein); n=2; Bos taurus|Rep: TBC1 domain family member
            1 (Lyncein) - Bos Taurus
          Length = 1056

 Score = 74.5 bits (175), Expect = 1e-11
 Identities = 35/83 (42%), Positives = 50/83 (60%)

Query: 273  DREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENL 332
            D+EVGYCQG  F+ G+LL+ M EEEAF +L  +M    +R  ++P M  L + M+QL  L
Sbjct: 927  DQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRL 986

Query: 333  VQELLPDLHVHFQSQSFSTSLYA 355
            + +   DL+ H +      SLYA
Sbjct: 987  LHDYHRDLYNHLEEHEIGPSLYA 1009


>UniRef50_Q9Y7J5 Cluster: GTPase activating protein; n=1;
           Schizosaccharomyces pombe|Rep: GTPase activating protein
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 414

 Score = 74.5 bits (175), Expect = 1e-11
 Identities = 42/122 (34%), Positives = 67/122 (54%), Gaps = 4/122 (3%)

Query: 197 QGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKA-KSACEKVIR--RDIARTYPEHDFFKE 253
           +G+P  +R I W     VD+ P+KKL   Y +  +  C+  ++   D+ RT   H  F++
Sbjct: 157 KGIPDCWRSIAWWSFL-VDSLPDKKLIDKYYQLNEQICDYDVQIDLDVPRTAATHFLFRK 215

Query: 254 KDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRD 313
           +   GQ  LF V+ A +L+   VGY QG   I   LL+  PEE+AF ++V +++   M D
Sbjct: 216 RYIGGQRLLFRVLHAVALYIPRVGYVQGMASIAATLLIYYPEEQAFIMMVNLLENRGMGD 275

Query: 314 MF 315
           +F
Sbjct: 276 LF 277


>UniRef50_Q6CDM5 Cluster: Similar to sp|P48566 Saccharomyces
           cerevisiae YNL293w MSB3; n=1; Yarrowia lipolytica|Rep:
           Similar to sp|P48566 Saccharomyces cerevisiae YNL293w
           MSB3 - Yarrowia lipolytica (Candida lipolytica)
          Length = 660

 Score = 74.1 bits (174), Expect = 2e-11
 Identities = 51/180 (28%), Positives = 92/180 (51%), Gaps = 12/180 (6%)

Query: 175 RLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA------GVDTSPEKKLYASYIK 228
           R+ S   + +  +++ ++  VR+G+P  +RG  W   A        +     KL      
Sbjct: 308 RVPSTGPTRFPPKSEKLKRYVRKGIPAEWRGQAWFWFARGYEYLNANVGVYDKLCEKSAT 367

Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQES-----LFNVMKAYSLHDREVGYCQGSG 283
             +   ++I RD+ RT+P++ +F++ +G   E+     L  V++A++LH  +VGYCQ   
Sbjct: 368 MDTVDAELIERDLYRTFPDNVYFRKAEGEVDETPMIMALRRVLRAFALHHPKVGYCQSLN 427

Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
           F+ GLLL+ M EE AF +L  I+ Q  +  +   ++  + +    L  LVQ+ LP +  H
Sbjct: 428 FLAGLLLLFMDEERAFWML-HIITQKYLPGVHDTNLEGVNVDQGVLMLLVQKSLPAVWRH 486


>UniRef50_O94711 Cluster: GTPase activating protein Gyp2; n=1;
           Schizosaccharomyces pombe|Rep: GTPase activating protein
           Gyp2 - Schizosaccharomyces pombe (Fission yeast)
          Length = 720

 Score = 74.1 bits (174), Expect = 2e-11
 Identities = 54/230 (23%), Positives = 106/230 (46%), Gaps = 10/230 (4%)

Query: 194 LVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKA--KSACE--KVIRRDIARTYPE 247
           LV+ G+P++ R  +W+  +G        K  YA  I +   + CE  + I +D+ R+ P+
Sbjct: 212 LVQSGIPNNLRADIWETCSGSLFPRWKSKGFYAKNIDSVINNRCEYSEEIEKDLTRSLPD 271

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQ 307
           +  ++   G+   +L  ++  YS  ++EVGYCQ    ++  LL+   EE+A+ +  ++ +
Sbjct: 272 YPAYQSPTGIN--TLRRILLFYSETNKEVGYCQAMNIVLAALLVYCTEEQAYFLFSQLCE 329

Query: 308 QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXX 367
            + +   +   +  L L +   E +++  LP L+           L              
Sbjct: 330 FY-IPGYYAKIIHGLLLDLTVFEYVLEHTLPHLYQKIIELDMDLKLITINWFFSLFIKDF 388

Query: 368 XXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL-SLDMESILKYIQK 416
               A RI+D     G  ++F+VALAL  +    +L + D  S++K  ++
Sbjct: 389 RLDYAFRILDCLFVNGPRVLFQVALALFKVNAQGILNATDDSSVMKVFRQ 438


>UniRef50_A6QZT7 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 892

 Score = 73.7 bits (173), Expect = 2e-11
 Identities = 43/158 (27%), Positives = 79/158 (50%), Gaps = 3/158 (1%)

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
           I +D+ R+ PE+  F+ ++G+G+  L  V+ AYS  + E+GYCQ    +V  LL+   E 
Sbjct: 289 IEKDLNRSLPEYPGFQSEEGIGR--LRRVLTAYSWINEEIGYCQAMNIVVAALLIYTSET 346

Query: 297 EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAX 356
           +AF  L+ ++ Q  +   +  +M    L     E+LV++ +P L  H        S+ + 
Sbjct: 347 QAF-FLLSVLCQRLLPGYYSTTMYGTLLDQKVFESLVEKTMPVLWEHLVRSDVQLSVVSL 405

Query: 357 XXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
                          A R++DVF  EG +++F++ + +
Sbjct: 406 PWFLSLYINSMPLVFAFRVLDVFFLEGPKVLFQIGVGV 443


>UniRef50_Q09445 Cluster: Uncharacterized protein C04A2.1; n=2;
           Caenorhabditis|Rep: Uncharacterized protein C04A2.1 -
           Caenorhabditis elegans
          Length = 330

 Score = 73.7 bits (173), Expect = 2e-11
 Identities = 57/217 (26%), Positives = 102/217 (47%), Gaps = 10/217 (4%)

Query: 180 WESEWKRRNQWV-RDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKVIR 238
           WE E  RRN  + +  VR+G+PH FR  +W        S    ++  + +      K I+
Sbjct: 59  WEKENPRRNSHLLQRFVRKGIPHTFRKELWLRSC---PSRADGVWQRH-EVPDEVIKQIK 114

Query: 239 RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE-E 297
            D+ RT+P++ F K +    +++L   + A + H   VGYCQG  F+ G++L+ + +E  
Sbjct: 115 LDLPRTFPDNKFLKTEGT--RKTLGRALFAVAEHIPSVGYCQGLNFVAGVILLVVNDESR 172

Query: 298 AFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXX 357
           A  +LV ++ Q   ++ +  +M  L   M  L +L++E  P + V  +       +    
Sbjct: 173 AIDLLVHLVSQR--QEYYGKNMIGLRRDMHVLHSLLREHCPRVVVTLEKLDVGLDMLVGK 230

Query: 358 XXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
                           R+ D  + EG E +F++A+AL
Sbjct: 231 WFVCWFVESLPMETVLRLWDCLIYEGDEWLFRIAVAL 267


>UniRef50_A6QUK8 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 1043

 Score = 73.3 bits (172), Expect = 3e-11
 Identities = 51/166 (30%), Positives = 77/166 (46%), Gaps = 11/166 (6%)

Query: 187 RNQW--VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACE------KVIR 238
           R +W   R+LV  G+P  +R  +W   +G         Y   +K  +  +        I 
Sbjct: 668 RAKWREFRNLVIGGIPVAYRAKIWSECSGASAMRVPGYYDDLVKGNTNLDTDPSVVSQIE 727

Query: 239 RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMP-EEE 297
            DI RT  ++ FF++  G G E L+ V+ AYS  + +VGYCQG   I G LL+ MP  E+
Sbjct: 728 MDIHRTLTDNVFFRK--GPGVEKLYEVLLAYSRRNPDVGYCQGMNLIAGSLLLIMPTAED 785

Query: 298 AFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
           AF +LV +++       +   +         L   V E+LP L  H
Sbjct: 786 AFWILVSLIENILPAHYYDHGLLASRADQQILRQYVAEILPKLSAH 831


>UniRef50_UPI00005A4648 Cluster: PREDICTED: similar to USP6
           N-terminal like protein (Related to the N terminus of
           tre) (RN-tre); n=2; Canis lupus familiaris|Rep:
           PREDICTED: similar to USP6 N-terminal like protein
           (Related to the N terminus of tre) (RN-tre) - Canis
           familiaris
          Length = 557

 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 38/124 (30%), Positives = 60/124 (48%), Gaps = 2/124 (1%)

Query: 274 REVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLEN 331
           +EVGYCQG   I  +LLM +PEE+AF  L ++M   +H M   F P   +L       E 
Sbjct: 282 QEVGYCQGMSEIAAILLMFLPEEDAFWALAQLMTNDRHAMHGFFIPGFPKLLRFQAHHER 341

Query: 332 LVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVA 391
           +++  LPDL  H   +  ST +Y               PL  ++ D ++ +G  ++  +A
Sbjct: 342 VLERALPDLRKHMDEEQMSTGIYTPKRFLQCFLGRTPFPLTLKLWDAYVLDGERVLTAMA 401

Query: 392 LALL 395
             +L
Sbjct: 402 YTIL 405


>UniRef50_O96904 Cluster: Drainin; n=2; Dictyostelium
           discoideum|Rep: Drainin - Dictyostelium discoideum
           (Slime mold)
          Length = 438

 Score = 72.5 bits (170), Expect = 5e-11
 Identities = 50/211 (23%), Positives = 93/211 (44%), Gaps = 3/211 (1%)

Query: 236 VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPE 295
           +I +DI  T+P    F +K G     L +V+ AY  +  ++GY  G  F+  + L+ M +
Sbjct: 228 LILQDIQDTFPSLMIF-QKGGPLHSDLIDVLGAYICYRPDIGYVPGMTFLAAMFLLNMEK 286

Query: 296 EEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
            +AF  L   +        F+   + +   +  +++ V+ L P LH HF+    S   Y 
Sbjct: 287 CDAFLSLSNHINSVCFLPFFRQDQSGIPKYLAAMDSTVEALTPPLHKHFKEIGISAKNYL 346

Query: 356 XXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQ 415
                          +A RI D+   EG   +++ AL++L    +DL+    +  +    
Sbjct: 347 VDWITTLFSKALPLDVATRIWDLVFIEGEIFIYRTALSILRYFISDLIQATYDECIDLFN 406

Query: 416 KELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
           K LP +  ++   F  +  S+ ++ +K  KL
Sbjct: 407 K-LPQRKISEDKLFEEI-QSIVLDQRKFDKL 435


>UniRef50_Q5DGV1 Cluster: SJCHGC08537 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC08537 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 197

 Score = 71.7 bits (168), Expect = 8e-11
 Identities = 43/139 (30%), Positives = 74/139 (53%), Gaps = 12/139 (8%)

Query: 171 SLWGRLVSNWESEWK----RRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKL 222
           S+  R VS WE  +     +R+   +   R+G+P H R  VW  L+G    + ++P+   
Sbjct: 34  SVLQRRVSRWEKYFSALPSKRSARFKRFCRKGIPDHIRSTVWMHLSGAYERMKSNPDAYQ 93

Query: 223 YASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQE--SLFNVMKAYSLHDREVGYCQ 280
            A      +    VI  D+ RT+PE+  F++ DG   +  SL  V+ A+++H  ++GYCQ
Sbjct: 94  LAVSKTPPANIWNVILADVPRTFPENKHFQDTDGPNNKLVSLKRVLSAFAVHFPQIGYCQ 153

Query: 281 GSGFIVGLLLMQM--PEEE 297
           G  +I  +LL+ +  P++E
Sbjct: 154 GMNYIAAVLLLVLDCPQDE 172


>UniRef50_A0ECU1 Cluster: Chromosome undetermined scaffold_9, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_9,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 948

 Score = 71.7 bits (168), Expect = 8e-11
 Identities = 47/189 (24%), Positives = 83/189 (43%), Gaps = 11/189 (5%)

Query: 234 EKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQM 293
           E++I  D+ R+   H      D +    L + ++ Y+ H++EVGYCQG  +IVG L +  
Sbjct: 696 EEIITMDVQRSLQLHF-----DRVPSSKLQSFLRTYAFHNKEVGYCQGMNYIVGYLYLTF 750

Query: 294 PEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSL 353
            +EE   ++   + ++     F+     L    +Q E L+   LP+L+ HF+ Q    S 
Sbjct: 751 EDEEVTYIVFDYIMRNYFSQYFENEFEMLKKVFYQYERLLFLFLPNLYHHFKKQKVDASY 810

Query: 354 YAXXXXXXXXXXXXXXPLACRIMDV------FLSEGIEIVFKVALALLTLGKNDLLSLDM 407
           Y                +   I  +       + E I   +K  L LL   + +LL L+ 
Sbjct: 811 YLTAWFITFTLQSALLNIIWDIFIIQQWKGNIIKEQILGFYKCVLFLLYFYQKELLLLEF 870

Query: 408 ESILKYIQK 416
           + IL ++ +
Sbjct: 871 DQILHFLSE 879


>UniRef50_UPI0000498A13 Cluster: Rab GTPase activating protein; n=1;
           Entamoeba histolytica HM-1:IMSS|Rep: Rab GTPase
           activating protein - Entamoeba histolytica HM-1:IMSS
          Length = 618

 Score = 71.3 bits (167), Expect = 1e-10
 Identities = 68/313 (21%), Positives = 140/313 (44%), Gaps = 18/313 (5%)

Query: 153 HEVETRPTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA 212
           ++V+ +       E++    W +++  W+     +   + + V +GVP ++R  +W+ L 
Sbjct: 311 YDVKIQSNQKIKQEKNRNKKWKKMIEIWKETVPHK---LSERVMKGVPMNYRRDLWKKLL 367

Query: 213 GVDTSPEK--KLYASYIKA--KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKA 268
            +D   EK  K Y    +   +S  +K I  DI RT+  H  FK +   GQ+ LFNV+ +
Sbjct: 368 EIDNIDEKILKEYKELNEKDNRSEHDKQIDLDINRTFQLHYNFKIRYCGGQKELFNVLHS 427

Query: 269 YSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIM-QQHRMRDMFKPSMAELGLCMF 327
            S  + E+GY QG   ++ +  M + EEEA+A   KI   +++ ++MF     +L   ++
Sbjct: 428 LSETEPELGYVQGMSSVISVFTMFLKEEEAYAGAKKICGDKYKWKEMF--LNFDLIQKLW 485

Query: 328 QLENLV-QELLPDLHVHFQSQSF---STSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG 383
           ++  ++ +E  P +  H +           +                ++ R+ D  L +G
Sbjct: 486 KITGIIMKEHYPQMFDHLKKLEIIDCPMPFFIFEWHYLWYVHAFNFEISLRVFDFILMDG 545

Query: 384 IEIVFKVALALLTLGKNDLLSL----DMESILKYIQKELPLKAEADQAAFMNLAYSVKVN 439
              +  VA  ++   ++++L +    D++  LK     LP +       FM+     +  
Sbjct: 546 FCALMSVARTIMFYIQDEVLKIKTNEDLQQKLKTPLLLLPKEKRPTANMFMSTVEKKRFT 605

Query: 440 PKKMKKLEKEYTV 452
             ++ +L  + T+
Sbjct: 606 QDQVNELLNQCTL 618


>UniRef50_A7SUG8 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 543

 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 35/98 (35%), Positives = 59/98 (60%), Gaps = 3/98 (3%)

Query: 214 VDTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQE---SLFNVMKAYS 270
           V +SP+++  ++ + AK    + I  D+ R++P H  F +    G+E   SLF V+  Y+
Sbjct: 154 VPSSPKQETTSNELHAKMTHMRQIMLDVERSFPTHKMFIDGSTEGKEGRASLFRVLAVYA 213

Query: 271 LHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQ 308
            ++ +V YCQG  +I G+LLM M EE+AF  LV + ++
Sbjct: 214 HYNTQVSYCQGMSYIAGMLLMNMDEEDAFWCLVSLFER 251


>UniRef50_A0D8F0 Cluster: Chromosome undetermined scaffold_41, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_41,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 345

 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 48/185 (25%), Positives = 90/185 (48%), Gaps = 13/185 (7%)

Query: 248 HDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMP--------EEEAF 299
           +DFF     L Q  LF +++AY+  D  +GY QG  +I+GLLL  +         E +A+
Sbjct: 150 NDFFS----LNQRRLFYLLRAYANQDPSIGYVQGMNYIMGLLLFLLDDSNSLFSGEMKAY 205

Query: 300 AVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
            + + I  +      +  SM +L   +  +E L+Q+ LPD++    +       +     
Sbjct: 206 QMFLFINVKMNWSQTYNKSMKKLKSMVQHVEVLLQQNLPDVYKVICNLDQPFIFFMDQYF 265

Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQKEL 418
                       + +I+D+F+ +G +I+F V L + TL +N++  L D +   ++I++ L
Sbjct: 266 FGLMSYKTPLEFSAKILDIFIIQGEQIIFDVLLRVFTLNRNEIKQLYDKDEQTQFIKEIL 325

Query: 419 PLKAE 423
           P+  E
Sbjct: 326 PMSIE 330



 Score = 35.9 bits (79), Expect = 4.9
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSA 232
           W   + N + ++  RNQ +  L +   P   R I++  +A   T P    Y  + +   A
Sbjct: 43  WKEYIQNVDFQYMDRNQVLSQLKKNFDPS-LRSIIYPWIAN-KTVPSPIDYKLFAQNPCA 100

Query: 233 CEKVIRRDIARTYPEHDFFKEK 254
            + +I RDI RT+    F+K K
Sbjct: 101 QDNIIFRDIERTHSHLQFYKSK 122


>UniRef50_UPI0000ECC2F9 Cluster: TBC1 domain family member 2
           (Prostate antigen recognized and identified by SEREX)
           (PARIS-1).; n=2; Gallus gallus|Rep: TBC1 domain family
           member 2 (Prostate antigen recognized and identified by
           SEREX) (PARIS-1). - Gallus gallus
          Length = 807

 Score = 70.5 bits (165), Expect = 2e-10
 Identities = 48/201 (23%), Positives = 83/201 (41%), Gaps = 5/201 (2%)

Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACE----KVIRRDIARTYP 246
           ++ L+R G+P   R  VW+ +     S     Y   ++   + E    + I  D+ RT  
Sbjct: 607 LKSLIRSGIPVEHRQRVWKWIVSQHCSYLPDHYQRLLRQSKSTEHPACRQIELDLPRTLT 666

Query: 247 EHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLVKI 305
            +  F          L  V+ A+S H+  +GYCQG   +  + L+ + +EE AF  LV I
Sbjct: 667 NNKHFSSPTSQLIPKLRRVLLAFSWHNPAIGYCQGLNRLAAVALLVLEDEENAFWCLVHI 726

Query: 306 MQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXX 365
           ++     D +  ++    +     ++ + E LP L  HF+      SL            
Sbjct: 727 VENLMPADYYSDTLITSQVDQRVFKDFLAEKLPRLMAHFEHYQIDVSLITFNWFLVAFVD 786

Query: 366 XXXXPLACRIMDVFLSEGIEI 386
                +  R+ D FL EG ++
Sbjct: 787 SLVSDILLRVWDAFLYEGTKV 807


>UniRef50_Q1EB21 Cluster: Putative uncharacterized protein; n=2;
           Eurotiomycetidae|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 1136

 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 58/171 (33%), Positives = 82/171 (47%), Gaps = 21/171 (12%)

Query: 187 RNQW--VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKS---ACEKVIRR-- 239
           R +W   R LV  G+P  +R  +W   +G         Y   +K  S   A   +I +  
Sbjct: 773 RAKWREFRTLVLGGIPVAYRAKIWAECSGASAMRVPGYYEDLVKESSNHDADPSIIAQID 832

Query: 240 -DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMP-EEE 297
            DI RT  ++ FF++  G G   L  V+ AYS  + EVGYCQG   I G LL+ MP  E+
Sbjct: 833 MDINRTLTDNVFFRK--GPGVAKLKEVLLAYSRRNPEVGYCQGMNLIAGSLLLIMPTAED 890

Query: 298 AFAVLVKIMQQHRMRDMFKPSMAELGLCMFQ-----LENLVQELLPDLHVH 343
           AF VL  I+++     +F P   + GL   +     L   V E+LP L +H
Sbjct: 891 AFWVLTSIIEK-----IFPPHYYDHGLVASRADQQVLRQYVAEILPKLSLH 936


>UniRef50_UPI00006CBFC6 Cluster: TBC domain containing protein; n=1;
            Tetrahymena thermophila SB210|Rep: TBC domain containing
            protein - Tetrahymena thermophila SB210
          Length = 1753

 Score = 69.7 bits (163), Expect = 3e-10
 Identities = 54/246 (21%), Positives = 108/246 (43%), Gaps = 16/246 (6%)

Query: 186  RRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAK---------SACEKV 236
            ++N++++ L ++G P  +R   W++   ++    ++ Y      +            +K 
Sbjct: 1336 QKNEFLKAL-KKGPPMWYRWSAWKVALDLNVEEYRETYEKLKPTEPLNFDHTYTDPIDKQ 1394

Query: 237  IRRDIARTYPEHDFFKEKDGLGQ--ESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM--Q 292
            I +DI RT P+  FF +     +  +SL NV+KA SL+   VGYCQG  F+   LL+   
Sbjct: 1395 INKDITRTIPDEPFFSDPQYSQKSLQSLRNVLKAVSLYYDNVGYCQGMNFLAAFLLLING 1454

Query: 293  MPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTS 352
              E +AF++ +++ ++  +  +F+     +    F  +       P L  HF       +
Sbjct: 1455 GDELQAFSMFIQMEKKLNIMGLFEEEFPLIQFMNFVFQREFGRKFPKLFRHFNKLKIPET 1514

Query: 353  LYAXXXXXXXXXXXXXXPLACRIMD-VFLSEGIEIVFKVALALLTLGKNDLLSL-DMESI 410
            ++                + CR  D +F    I     ++L+L+      L+   +++ I
Sbjct: 1515 MWVVQWFQTIFLNSLSLNVVCRFWDYIFYQGSIISAISISLSLIHEYNAHLIKKNELDEI 1574

Query: 411  LKYIQK 416
             ++IQK
Sbjct: 1575 SQFIQK 1580


>UniRef50_Q55EP9 Cluster: RabGAP/TBC domain-containing protein; n=1;
           Dictyostelium discoideum AX4|Rep: RabGAP/TBC
           domain-containing protein - Dictyostelium discoideum AX4
          Length = 366

 Score = 69.7 bits (163), Expect = 3e-10
 Identities = 52/214 (24%), Positives = 97/214 (45%), Gaps = 5/214 (2%)

Query: 191 VRDLVRQ-GVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHD 249
           + D  +Q G     RG++W++L GVD     K      K  S   + IR+DI RT+    
Sbjct: 55  IEDRTKQDGSKCSLRGMIWKILLGVDKIQPDKYIELIEKGPSNRYQKIRKDIGRTFNRDS 114

Query: 250 FFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQH 309
            F +   + Q+ L   + A++    E+GY QG   I G  L  +PE EAF     ++ Q 
Sbjct: 115 QFSQ--AVSQDQLSRCLNAFAHQCEELGYVQGMNAICGTFLYVLPEVEAFQCFYSLLTQ- 171

Query: 310 RMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXX 369
              + F  +++ +      L+ +++ + P+L+ + Q++S+   L+               
Sbjct: 172 CCPNYFTSNISGVNDASKLLDRILEFVDPELYEYLQNRSYHPLLFTPPILSLGTATPPLD 231

Query: 370 PLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
            L  ++ D FL+ G  +     ++ + L ++ LL
Sbjct: 232 EL-LKLWDFFLAFGFHLNVICTISQILLMRDVLL 264


>UniRef50_Q6CXK6 Cluster: Similarities with sp|P48566 Saccharomyces
           cerevisiae YNL293w MSB3; n=2; Saccharomycetaceae|Rep:
           Similarities with sp|P48566 Saccharomyces cerevisiae
           YNL293w MSB3 - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 619

 Score = 69.7 bits (163), Expect = 3e-10
 Identities = 52/182 (28%), Positives = 93/182 (51%), Gaps = 18/182 (9%)

Query: 182 SEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKL-----YASYIKAKSACEK- 235
           S +  +++ ++  VR+G+P  +RG  W   A       K +       + I   S   K 
Sbjct: 238 SRFPSKSEKLKRYVRKGIPAEWRGNAWWYFARGQELLNKNIGVYDKLLTKINDPSFTSKD 297

Query: 236 --VIRRDIARTYPEHDFFKE-----KDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
             +I RD+ RT+P++  F+      +D L  +SL  ++KA+++++ ++GYCQ   F+VGL
Sbjct: 298 TEIIERDLHRTFPDNIHFQRSKVSSEDPLIIKSLRRILKAFAIYNAKIGYCQSMNFLVGL 357

Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
           LL+ M EE AF +LV IM    +  +   ++  + +    L   ++E LP    HF  + 
Sbjct: 358 LLLFMDEERAFWMLV-IMTSRYLPGVHSINLEGVNINQGVLLLCIKEYLP----HFWQRI 412

Query: 349 FS 350
           +S
Sbjct: 413 YS 414


>UniRef50_UPI000049A372 Cluster: Rab GTPase activating protein; n=1;
           Entamoeba histolytica HM-1:IMSS|Rep: Rab GTPase
           activating protein - Entamoeba histolytica HM-1:IMSS
          Length = 478

 Score = 69.3 bits (162), Expect = 4e-10
 Identities = 63/249 (25%), Positives = 111/249 (44%), Gaps = 13/249 (5%)

Query: 173 WGRLVS-NWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDT-SPEKK---LYASYI 227
           W R++  NW+     + Q   + V +GVP  +R + W+ + G++  S E K      + I
Sbjct: 197 WERMLDKNWDENIPVKLQ---ERVYKGVPDDYRILYWKRILGIEEISQELKEEFKRNTQI 253

Query: 228 KAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
            ++S  +K +  D+ R++  H  F  +   GQ+ LF VM A SLHD    Y QG      
Sbjct: 254 YSRSPHDKQLDLDVNRSFQFHYKFHVRYSGGQKELFYVMHAISLHDISFDYVQGISCAPS 313

Query: 288 LLLMQMPEEEAFAVLVKIM-QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
           +L + + E  AFA  +K+   ++R+++MF+     +  C    + L+    P +   F+ 
Sbjct: 314 VLCIFLDELSAFAGTLKLFTSKYRLKEMFQ-DFNFIKKCWIVTKKLLDTRHPKIAEKFRQ 372

Query: 347 ---QSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
                 S   +                LA R+ DV L EG   +F V+  +    +  +L
Sbjct: 373 CGIMDQSLPFFMFEWNYLWFIHSLKFELAIRVFDVILLEGFTAMFSVSDTIFHFIEEGIL 432

Query: 404 SLDMESILK 412
           +    +IL+
Sbjct: 433 NEKDPNILQ 441


>UniRef50_Q9ZUT7 Cluster: Putative uncharacterized protein
           At2g37290; n=2; Arabidopsis thaliana|Rep: Putative
           uncharacterized protein At2g37290 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 544

 Score = 69.3 bits (162), Expect = 4e-10
 Identities = 55/175 (31%), Positives = 75/175 (42%), Gaps = 32/175 (18%)

Query: 194 LVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI-----------KAKSACEKVIRRDIA 242
           LVR GVP   RG VWQ   GV     ++ Y   +             +   +K I +DI 
Sbjct: 183 LVRLGVPKDLRGEVWQAFVGVKARRVERYYQDLLAQITNSDENSSDVQRKWKKQIEKDIP 242

Query: 243 RTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQ-----------------GSGFI 285
           RT+P H    E    G++SL  ++ AY+ H+  VGYCQ                    F 
Sbjct: 243 RTFPGHPALNEN---GRDSLRRILLAYACHNPSVGYCQVTWARKSIFEYPIALIVAMNFF 299

Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDL 340
            GLLL+ MPEE AF  LV I+  +     +   M E  +     E L++E  P L
Sbjct: 300 AGLLLLLMPEENAFWTLVGIIDDY-FDGYYTEEMIESQVDQLVFEELMRERFPKL 353


>UniRef50_A0CB10 Cluster: Chromosome undetermined scaffold_163,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_163,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 288

 Score = 69.3 bits (162), Expect = 4e-10
 Identities = 58/233 (24%), Positives = 103/233 (44%), Gaps = 18/233 (7%)

Query: 193 DLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFK 252
           +LVRQG P   R   W+ +   +  P          +K + E +I +DI RT   H FF+
Sbjct: 8   NLVRQGPPSKLRWAAWKSILLKNEYP--------FNSKGSSE-LINKDIKRTLINHPFFQ 58

Query: 253 EKDG---LGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE--AFAVLVKIMQ 307
                  +GQ  L+N+++A S +  ++GYCQG  F+ G LL+    +E  ++  LV ++ 
Sbjct: 59  STQDDYTIGQYQLYNILQALSNYYPKLGYCQGMNFLAGFLLLVSGGDEYYSYQCLVTLLT 118

Query: 308 QHRMRDMFK--PSMAELGLCMFQLENLVQELLPDLHVHFQSQ-SFSTSLYAXXXXXXXXX 364
             +    F    +   LG   F  + L+Q  LP L+ H   Q ++  S +          
Sbjct: 119 HPKFMLYFNYDSNFQLLGFLEFITQKLLQLHLPSLYKHLYRQLNYPESFWLTKIILTLFL 178

Query: 365 XXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQK 416
                    R  D  + EGI  +  + + +L   ++ +L++ +   I  + Q+
Sbjct: 179 YNFQLQHCLRFWDYIIVEGIFYLPSLVIKILDQFQSQILAIHEFSDIAMWFQQ 231


>UniRef50_A4R2B1 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 982

 Score = 69.3 bits (162), Expect = 4e-10
 Identities = 57/214 (26%), Positives = 91/214 (42%), Gaps = 14/214 (6%)

Query: 181 ESEWKRRNQWVRDLVRQGVPHHFRGIVW-QLLAGV-----DTSPEKKLYASYIKAK---S 231
           E E+   N  V D   +G+P  +R   W   LA        T+ +K L A + + +   S
Sbjct: 695 EFEFDPTNSKVIDRTWKGIPDRWRAAAWYSFLASSAKKHGSTTTDKDLVAEFQRLQYVSS 754

Query: 232 ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM 291
           + +  I  D+ RT   H  F+ +   GQ  LF V+ A SLH  + GY QG   +   LL 
Sbjct: 755 SDDTQIDLDVPRTINRHIMFRRRYRGGQRLLFRVLHALSLHFPDTGYVQGMAPLAATLLC 814

Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLP--DLHVHFQSQSF 349
              EE+ F +LV++ +   +  +++P  A L   M  L++  ++ LP  D+         
Sbjct: 815 YYDEEKTFIMLVRMWRYRGLERLYQPGFASL---MTALKDFERDWLPSNDIARKLSELCI 871

Query: 350 STSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG 383
             + YA                  R+ DVF+  G
Sbjct: 872 DPTAYATRWYLTLFNLSIPFQAQLRVWDVFMLLG 905


>UniRef50_UPI0000F216EC Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 540

 Score = 68.9 bits (161), Expect = 6e-10
 Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 4/190 (2%)

Query: 235 KVIRRDIARTYPEHDFFK--EKDGL-GQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLM 291
           K I  D+ R++P H        + + GQ  LF V+ A++ ++  +GY QG  +I  +LLM
Sbjct: 166 KQIALDLQRSFPTHRTLMGDRPEAIEGQAKLFRVLSAFARYNPLIGYVQGMSYIAAVLLM 225

Query: 292 QMPEEEAFAVLVKIMQQHR-MRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFS 350
            + EEEAF  LV ++++ + + ++F  SM ++         L++   P L  H ++   S
Sbjct: 226 ILSEEEAFWALVALLEKPKYLSELFDSSMKKIQHQALVFHQLLKHRKPLLFQHLETLGVS 285

Query: 351 TSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESI 410
              +                    I D+ +  G++ VF+  L ++ L ++ ++++  E+ 
Sbjct: 286 CVHFIMQWFLTLFTSLPCWDSVLAIWDLIMLHGLQAVFRTGLTIILLLESRIMNMTEEAT 345

Query: 411 LKYIQKELPL 420
           +  +   +P+
Sbjct: 346 VLPLLLRVPI 355


>UniRef50_Q940C5 Cluster: AT3g55020/T15C9_20; n=11;
           Magnoliophyta|Rep: AT3g55020/T15C9_20 - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 465

 Score = 68.5 bits (160), Expect = 7e-10
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 4/107 (3%)

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
           I +D+ RT+P H      D  G+ +L  ++ AY+ H+  VGYCQ   F   LLL+ MPEE
Sbjct: 310 IEKDLPRTFPGHPAL---DDDGRNALRRLLTAYARHNPSVGYCQAMNFFAALLLLLMPEE 366

Query: 297 EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
            AF  L+ ++  +     +   M E  +    LE LV+E  P L  H
Sbjct: 367 NAFWALIGLIDDY-FNGYYSEEMIESQVDQLVLEELVRERFPKLVHH 412


>UniRef50_A2EMR6 Cluster: Viral A-type inclusion protein, putative;
            n=4; cellular organisms|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2416

 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 79/351 (22%), Positives = 162/351 (46%), Gaps = 37/351 (10%)

Query: 493  VRGQVDRAEGEEETFA-LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSL 551
            ++ +++R EG +E    L +E   L + N +++++L     +I+S E    E     + +
Sbjct: 735  LKDRINRGEGGDEVVEELAKENDELSKENEELKEKLK----DIKSSE----EIEELTNQI 786

Query: 552  EGTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDN 611
            E  E    +K E+L +                          I+ L+NE + L ++    
Sbjct: 787  EELEKELNEKKEQLEQTENELTQQIEEIEEEKSEELKKKNEEIERLQNEIEELNKE---- 842

Query: 612  NVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD 671
             +  L +E+  ++ +   A   +++L++   +  E+ ++ + E K++   A      V+D
Sbjct: 843  -IKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTIDELKEKLRLA--NETKVTD 899

Query: 672  IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTEL--KELRLKVMELETQVQVST 729
              +  K L+ + E     +L L++E+   +I E+E L  +  +E   KV   E +     
Sbjct: 900  --SDTKVLVESKEAAEQKVLLLEKEISDLKI-EIEDLKSVIDEENEQKVSNTEAE----- 951

Query: 730  NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDA 789
            N++   + E   L++ LD    ++     +  + Q +  DL+S    E+ Q  + N E  
Sbjct: 952  NRIHELESEISELKKELDQNNNQQN--DEKIEKLQKEIEDLKSVIDEENEQ-KVSNTEAE 1008

Query: 790  QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
             RI ELE+E+SE  LK E+       +NNN  + +++ +LQ+++ +LK E+
Sbjct: 1009 NRIHELESEISE--LKKELD------QNNNQQNDEKIEKLQKEIEDLKNEL 1051



 Score = 51.2 bits (117), Expect = 1e-04
 Identities = 83/458 (18%), Positives = 195/458 (42%), Gaps = 34/458 (7%)

Query: 408  ESILKYIQKELPLKAEADQA--AFMNLAYSVKVNPKKMKK--LEKEYTVIKTKEQGDIAV 463
            E+IL+       +K + +Q      +L+ S  +N +K+ +  LE    + K KE+ D   
Sbjct: 1465 ETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAKEENDN-- 1522

Query: 464  LRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRRANVDM 523
               L +    L Q++                 +       E++F+L++EV+ L+      
Sbjct: 1523 ---LSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIF 1579

Query: 524  QQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXX 583
             ++     ++++S   T+ E +   ++L+     S +++E+L   L              
Sbjct: 1580 VEKSEEEKNKLKSEVTTLTEIS---ANLKQEIEISKEQNEKLKSML----SEVESNNEEL 1632

Query: 584  XXXXXXXXXXIDELENENKSLRRQRVD-NNVAHLQDELIAVKLREAEANLSLKDLRQRVS 642
                      I++L+ +N  + +Q  + N     +DE I   +  ++      D  +R +
Sbjct: 1633 KHTIEELSSQINDLQTQNDKVEKQIENLNKTIEEKDETINKMIANSD------DSEKRDN 1686

Query: 643  ELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRI 702
            E+ E + +   +  + +     +++    +++  K L +  E  +  + + ++E  T ++
Sbjct: 1687 EMKELFNKQNNKINELSKLIESKTSENDKLLSEIKDLNKENEELAVLVDEKEDENHTLQV 1746

Query: 703  REVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQRE 762
            R  E  +E  +L+  + ++E ++      L    +E   L +++++       L +   +
Sbjct: 1747 RIDEKDSENSQLKTDLSDIENKLNSGKELLNHTIDE---LTKSIESKSNENSKLMSAIDQ 1803

Query: 763  FQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD 822
                  DLE+K K     AN +N E+  ++ +L   V E K + E +  + E  +   + 
Sbjct: 1804 LN---KDLENKNKITEEIAN-KNEENESKLLDLNKVVEELKKQLEHVLIDNE--SEKQEK 1857

Query: 823  SDRVRELQEQVAELKAEIMRLEAWKSRALGH--TELSR 858
            SD  ++L+E++   + EI +L+    + + H  T++S+
Sbjct: 1858 SDTEQKLREEIEIKEKEIDKLKKQNDQQIDHFTTQISQ 1895



 Score = 46.8 bits (106), Expect = 0.003
 Identities = 68/346 (19%), Positives = 146/346 (42%), Gaps = 26/346 (7%)

Query: 499  RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
            + E E+    +D E +  + +N + + R+     EI  L+  + +NN++Q+         
Sbjct: 927  KIEIEDLKSVIDEENEQ-KVSNTEAENRIHELESEISELKKELDQNNNQQND-------- 977

Query: 559  GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
             +K E+L + ++                       I ELE+E   L+++ +D N     D
Sbjct: 978  -EKIEKLQKEIEDLKSVIDEENEQKVSNTEAENR-IHELESEISELKKE-LDQNNNQQND 1034

Query: 619  ELIAVKLREAE-ANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK 677
            E I    +E E     L+  +    EL   +++ + +  QE      Q   + +     K
Sbjct: 1035 EKIEKLQKEIEDLKNELESSKAENEELQNEFEKEIDQISQEKQNLESQIKYLQE--KGDK 1092

Query: 678  KLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDE 737
              +     ++ + L+   E M T+    E  +E++ L+ ++  +E   Q+S  + +  +E
Sbjct: 1093 SEIIDKLNQTIEELRAKVEHMFTQEDIDEYKSEIENLKQELSNIEKSKQISEEKSQDYEE 1152

Query: 738  EARLLRENLDA------ALQRERALQTRQRE-FQHKYADLESKAKYESMQANIRNMEDAQ 790
                L   L+A       L+ +   QTR+ E  +    +LE++ + E      RN  D +
Sbjct: 1153 IVHELENKLEAKETELSKLKSDFEQQTREIETLKENITNLENEMEIEKKN---RNSADNE 1209

Query: 791  RIAELETEVSEYKLK-NEVMATEGELRNNNMDDSDRVRELQEQVAE 835
            +I+ LE ++S+ + K  + + ++ E+      D   ++   +++ E
Sbjct: 1210 KISHLEKQISDLQNKLQDKIKSQNEMVEKFKRDFQEMQAKDQKIRE 1255



 Score = 42.3 bits (95), Expect = 0.056
 Identities = 37/165 (22%), Positives = 71/165 (43%), Gaps = 10/165 (6%)

Query: 684 EGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLR 743
           EG  A + K +EE      R++  L +LK   LK++E + +     N+   ++ + R+ R
Sbjct: 687 EGNLAMLQKENEEYQ----RQINELKDLKTEYLKLIEEKRETDEKYNK-EIEELKDRINR 741

Query: 744 -----ENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETE 798
                E ++   +    L     E + K  D++S  + E +   I  +E      + + E
Sbjct: 742 GEGGDEVVEELAKENDELSKENEELKEKLKDIKSSEEIEELTNQIEELEKELNEKKEQLE 801

Query: 799 VSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
            +E +L  ++   E E        ++ +  LQ ++ EL  EI  L
Sbjct: 802 QTENELTQQIEEIEEEKSEELKKKNEEIERLQNEIEELNKEIKSL 846



 Score = 39.9 bits (89), Expect = 0.30
 Identities = 62/342 (18%), Positives = 131/342 (38%), Gaps = 20/342 (5%)

Query: 512  EVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQX 571
            E++ L + N ++   +    DE  +L++ I E +S  S L+   S    K       L  
Sbjct: 1719 EIKDLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIENKLNSGKELLNH 1778

Query: 572  XXXXXXXXXXXXXXXXXXXXXXIDELEN--ENKSLRRQRVDNNVAHLQDELIAVKLREAE 629
                                  ID+L    ENK+   + + N     + +L+ +     E
Sbjct: 1779 TIDELTKSIESKSNENSKLMSAIDQLNKDLENKNKITEEIANKNEENESKLLDLNKVVEE 1838

Query: 630  ANLSLKDL-------RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRA 682
                L+ +       +Q  S+  +  +  ++  ++E      Q++   D   T    +  
Sbjct: 1839 LKKQLEHVLIDNESEKQEKSDTEQKLREEIEIKEKEIDKLKKQNDQQIDHFTTQISQIND 1898

Query: 683  WEGRSADMLKLDEELMTTRIRE--VEALTELKELRLKVMELETQ-VQVSTNQLR----RQ 735
                  D +  D +    +I+      + +LKE     +E   Q ++   +Q +    + 
Sbjct: 1899 DHNNEIDQINEDYQTQIDQIKHDHEREMNKLKENHQHEIESYKQNIEDLEHQFKEIGCKN 1958

Query: 736  DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI-AE 794
            DE    L + ++   + E  ++    +F  + +++    K E  Q NI+N E+  +I  +
Sbjct: 1959 DEYFNNLIDQINTKNKEE--IEKLNVQFTSQISEINENHKNEIEQINIKNQEEIMKINYQ 2016

Query: 795  LETEVSEY-KLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
              +++SE  +LK E      EL  +N +    +  L +++ E
Sbjct: 2017 FTSQISELNELKEEDNKKIYELCQDNSEKKKEIDRLNKEIEE 2058


>UniRef50_A0CZM7 Cluster: Chromosome undetermined scaffold_32, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_32,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 306

 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 50/188 (26%), Positives = 96/188 (51%), Gaps = 11/188 (5%)

Query: 235 KVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQM 293
           ++I RDI RTY +  +FK+K    Q+ +  ++  Y+ HD +VGY QG  FI G L+  Q+
Sbjct: 93  ELIDRDIGRTYQQIPYFKDKQN--QDKIRQLLVNYAQHDPDVGYVQGMNFIAGTLVYFQV 150

Query: 294 PEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSL 353
           P+ +   +  +++ +H  R+ +      L   + +L+  ++  +P L  H Q    +  L
Sbjct: 151 PQNQ--KIFNELIYKH--RNNYVTGTPGLFENLAKLKFKLKAKIPQLFKHLQEIGLN-DL 205

Query: 354 YAXXXXXXXXXXXXXXPLACR--IMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESI 410
                           P+  +  I++++   G + + K+ +A+L L K  L+ L D+E++
Sbjct: 206 GISFSPFYLTMMLQSTPIQYQMIILNIYQLMGQKYITKLLVAMLKLSKKALMKLKDVENV 265

Query: 411 LKYIQKEL 418
            KYI+ +L
Sbjct: 266 NKYIRTQL 273


>UniRef50_UPI00005A2F5A Cluster: PREDICTED: similar to USP6
           N-terminal like; n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to USP6 N-terminal like - Canis
           familiaris
          Length = 279

 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 36/79 (45%), Positives = 51/79 (64%), Gaps = 3/79 (3%)

Query: 235 KVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHD---REVGYCQGSGFIVGLLLM 291
           K I  DI RT+  H  F ++ G+GQ++LF+V+ AYS+++   +EVGYCQG   IV  LLM
Sbjct: 50  KQIDLDINRTFRNHIMFWDRYGVGQQALFHVLLAYSVYNILLQEVGYCQGMSQIVATLLM 109

Query: 292 QMPEEEAFAVLVKIMQQHR 310
            + EEEA   L ++M   R
Sbjct: 110 FLTEEEALWSLAQLMTNER 128


>UniRef50_UPI00006607B9 Cluster: Homolog of Homo sapiens "Plectin 3;
           n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens
           "Plectin 3 - Takifugu rubripes
          Length = 1246

 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 63/262 (24%), Positives = 130/262 (49%), Gaps = 14/262 (5%)

Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ-E 658
           E+K L +QR+D      Q  L A + R+ E     + L+ +VS+LSE+  +  +E K+ +
Sbjct: 414 EDKQLMQQRLDEETEEYQKSLEAERKRQMEITAEAEKLKLQVSQLSEAQAKAQEEAKKFK 473

Query: 659 APAAPVQSNVVSDIMATPKKLLRAWEGRSADM-LKLDEELMTTRIREVEALTELKELRLK 717
             A  + S +    MAT +K+    +   A M    + + + T I E+E   E   L+L+
Sbjct: 474 KQADSIASRLHETEMATKEKVTEVHKLELARMNTSKEADDLRTAIAELE--KEKARLKLE 531

Query: 718 VMELETQVQVSTNQLRRQDE-EARLLRENL----DAALQRERALQTRQREFQHKYADLES 772
             EL+ + +   +  ++Q E E  LL++         L++ER ++  +++ ++++ +   
Sbjct: 532 AEELQNKSKEMADAQQKQIELEKTLLQQTFLSEKQMLLEKERLIEEEKKKLENQFEEEVK 591

Query: 773 KAK--YESMQANIRNMEDAQR--IAELETEVSEYK-LKNEVMATEGELRNNNMDDSDRVR 827
           KAK   +  +   + MED ++   A +   +S+ K  + E+   + E++       ++ R
Sbjct: 592 KAKALQDEQERQRQQMEDEKKKLQATMNAALSKQKEAEKEMENKQKEMKELEEKRLEQER 651

Query: 828 ELQEQVAELKAEIMRLEAWKSR 849
            L E+  +L+ ++ +LEA K +
Sbjct: 652 LLAEENQKLREKLQQLEAQKEQ 673


>UniRef50_A0DIR7 Cluster: Chromosome undetermined scaffold_52, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_52,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 377

 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 50/186 (26%), Positives = 92/186 (49%), Gaps = 6/186 (3%)

Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV-GLLLMQMPE 295
           I +D+ RT+   D+F++++ L  + L +++ AYS  D EV Y QG  FIV  L+ +    
Sbjct: 131 IIKDVHRTFKSSDYFQKEEVL--QRLQDILVAYSNLDSEVSYGQGMNFIVAALMYLDFNN 188

Query: 296 EEA-FAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSF-STSL 353
           +EA F +L  I+     R ++      L L M +     ++ +P L+ HF        S+
Sbjct: 189 DEAIFEILRTIIMDKEWRQLYINGTPGLFLLMAKFNFKFKKRMPALYQHFLKLGIEDMSM 248

Query: 354 YAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILK 412
            A                +  ++ +F  EG +I+ K+ L+++   +N LL L D + I++
Sbjct: 249 CASAFYLTLCMQHAPIQFSLVLLAMFFIEGDDIITKMILSMIKYFENYLLKLNDFQQIIE 308

Query: 413 YIQKEL 418
           +I++ L
Sbjct: 309 FIKRGL 314


>UniRef50_UPI00006CB3B2 Cluster: TBC domain containing protein; n=1;
            Tetrahymena thermophila SB210|Rep: TBC domain containing
            protein - Tetrahymena thermophila SB210
          Length = 1092

 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 42/179 (23%), Positives = 81/179 (45%), Gaps = 2/179 (1%)

Query: 233  CEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQ 292
            C + I +D+ RT+P+ + F+ +  +   SL N+++  + +D  +GY QG   I   LL  
Sbjct: 864  CMQQIEKDLQRTFPQLEMFQNEKHIN--SLRNLLQTVAKYDPIIGYVQGMNMIGASLLYH 921

Query: 293  MPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTS 352
              E  +F ++  I ++  MRD++ P +  L   +  ++ +    + DL+ HF  Q  +  
Sbjct: 922  AEEYISFWIMQIIFEKLEMRDIYMPKLPGLSKHIQLIDFITLTRISDLYSHFCEQKITFD 981

Query: 353  LYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESIL 411
            ++                    ++   L EG  + +K+ +A L   K  L   DM  +L
Sbjct: 982  MFTTPWIFSLFGVVLTPQKLTILITELLEEGWLMFYKLVIAFLCYNKELLFQQDMGEML 1040


>UniRef50_UPI00005A05A7 Cluster: PREDICTED: similar to USP6
           N-terminal like, partial; n=4; Canis lupus
           familiaris|Rep: PREDICTED: similar to USP6 N-terminal
           like, partial - Canis familiaris
          Length = 738

 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 3/159 (1%)

Query: 281 GSGFIVGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLP 338
           G+  I  +LLM +PEE+AF  L ++M   +H M   F P   +L       E ++Q  LP
Sbjct: 428 GAQAIAAILLMFLPEEDAFWALAQLMTNDRHAMHGFFVPGFPKLLRFQAHHERVLQRALP 487

Query: 339 DLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLG 398
           +L  H   +  ST +Y                L  ++ D ++ +G  ++  +A  +L + 
Sbjct: 488 NLRKHMDEEQMSTDIYTPKCFLQCFLGRTPFLLTLKLWDAYIFDGERVLTAMAYTILKVH 547

Query: 399 KNDLLSLDMESILKYIQKELPLK-AEADQAAFMNLAYSV 436
           +  LL L +E + +++Q  L    A  D+A   +L  S+
Sbjct: 548 RKRLLKLPLEGLQEFLQDSLAQPWALEDEAVLRHLRASM 586


>UniRef50_A0E2P6 Cluster: Chromosome undetermined scaffold_75, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_75,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 473

 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 56/235 (23%), Positives = 105/235 (44%), Gaps = 7/235 (2%)

Query: 240 DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLL--MQMPEEE 297
           D  RT    D  K+K    ++ +  V+ AYS+ + E+GYCQG  FIV  L+  ++   E+
Sbjct: 154 DSVRTLNHLDSIKKKQI--EKQIETVLIAYSIRNPEIGYCQGQNFIVNYLINTLKFDLED 211

Query: 298 AFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXX 357
           AF    +I++     D +   ++ L      L+  +QE +P+L  HF   +  +  +   
Sbjct: 212 AFWTFTQILETIMPIDYYTNILSALTDQQI-LDYYIQEYIPELKTHFHKINLQSDFFTVQ 270

Query: 358 XXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMES-ILKYIQK 416
                        L   IM +   +GI+ +   AL LL L KN+LL  +  S + ++I +
Sbjct: 271 WYLCIFTNQVKPQLTNFIMLMLYIDGIKALTISALILLILLKNELLKFNQFSKLFRFIYQ 330

Query: 417 ELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTK-EQGDIAVLRCLRQE 470
            +     ++   ++ ++  + +   K K   K   + + K E     + + + QE
Sbjct: 331 LMQSIIYSNMQTYIAISKYLNITISKSKLKNKPLILPEKKLELNQFVIFKVISQE 385


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.316    0.130    0.360 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 781,669,045
Number of Sequences: 1657284
Number of extensions: 28637911
Number of successful extensions: 145019
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 532
Number of HSP's successfully gapped in prelim test: 4156
Number of HSP's that attempted gapping in prelim test: 128135
Number of HSP's gapped (non-prelim): 16945
length of query: 894
length of database: 575,637,011
effective HSP length: 107
effective length of query: 787
effective length of database: 398,307,623
effective search space: 313468099301
effective search space used: 313468099301
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 77 (35.1 bits)

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