Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000540-TA|BGIBMGA000540-PA|IPR000195|RabGAP/TBC
(894 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC014111-1|AAH14111.1| 794|Homo sapiens ecotropic viral integra... 530 e-150
AL354890-2|CAI21914.1| 810|Homo sapiens ecotropic viral integra... 448 e-125
AL133332-1|CAC19437.2| 810|Homo sapiens ecotropic viral integra... 448 e-125
AF008915-1|AAC16031.1| 810|Homo sapiens EVI-5 homolog protein. 442 e-123
AF042345-1|AAC16041.1| 607|Homo sapiens truncated EVI5 protein. 422 e-117
BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein. 251 7e-66
AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating p... 251 7e-66
AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating ... 251 7e-66
Z99127-7|CAI18937.1| 815|Homo sapiens RAB GTPase activating pro... 244 8e-64
AY364260-1|AAQ76819.1| 468|Homo sapiens HHL protein. 244 8e-64
AL591108-1|CAH70225.1| 815|Homo sapiens RAB GTPase activating p... 244 8e-64
AL161671-6|CAI16281.1| 815|Homo sapiens RAB GTPase activating p... 244 8e-64
AL136377-4|CAI22935.1| 815|Homo sapiens RAB GTPase activating p... 244 8e-64
AL031286-3|CAI22382.1| 815|Homo sapiens RAB GTPase activating p... 244 8e-64
AL022400-4|CAI22878.1| 815|Homo sapiens RAB GTPase activating p... 244 8e-64
AL022171-4|CAI20384.1| 815|Homo sapiens RAB GTPase activating p... 244 8e-64
AK095838-1|BAC04635.1| 815|Homo sapiens protein ( Homo sapiens ... 244 8e-64
AB209513-1|BAD92750.1| 307|Homo sapiens ecotropic viral integra... 168 7e-41
BC126979-1|AAI26980.1| 432|Homo sapiens TBC1D1 protein protein. 165 6e-40
BC053648-1|AAH53648.1| 891|Homo sapiens TBC1D1 protein protein. 165 6e-40
BC050321-1|AAH50321.3| 1168|Homo sapiens TBC1 (tre-2/USP6, BUB2,... 165 6e-40
BC014529-1|AAH14529.1| 900|Homo sapiens TBC1D1 protein protein. 165 6e-40
AK027355-1|BAB55057.1| 674|Homo sapiens protein ( Homo sapiens ... 165 6e-40
AB029031-1|BAA83060.1| 763|Homo sapiens KIAA1108 protein protein. 165 6e-40
AL162571-2|CAI39591.1| 1298|Homo sapiens TBC1 domain family, mem... 163 2e-39
AL139230-1|CAH70991.1| 1298|Homo sapiens TBC1 domain family, mem... 163 2e-39
AB011175-1|BAA25529.2| 1348|Homo sapiens KIAA0603 protein protein. 163 2e-39
D13644-1|BAA02807.2| 838|Homo sapiens KIAA0019 protein protein. 136 2e-31
BC042943-1|AAH42943.1| 828|Homo sapiens USP6 N-terminal like pr... 136 2e-31
AL590416-1|CAI16966.1| 828|Homo sapiens USP6 N-terminal like pr... 136 2e-31
AL512631-1|CAH70484.1| 828|Homo sapiens USP6 N-terminal like pr... 136 2e-31
BC062999-1|AAH62999.1| 446|Homo sapiens TBC1 domain family, mem... 130 3e-29
BC036873-1|AAH36873.3| 446|Homo sapiens TBC1 domain family, mem... 130 3e-29
CT841514-1|CAJ86444.1| 508|Homo sapiens dJ130H16.2 protein. 128 1e-28
AK074656-1|BAC11117.1| 508|Homo sapiens protein ( Homo sapiens ... 128 1e-28
AF331038-1|AAK35048.1| 508|Homo sapiens EPI64 protein. 128 1e-28
AC004997-3|AAC23434.1| 438|Homo sapiens WUGSC:H_DJ130H16.2 prot... 128 1e-28
BC098419-1|AAH98419.1| 668|Homo sapiens TBC1D10B protein protein. 116 5e-25
BC093816-1|AAH93816.1| 533|Homo sapiens TBC1 domain family, mem... 116 5e-25
BC093814-1|AAH93814.1| 533|Homo sapiens TBC1 domain family, mem... 116 5e-25
BC072453-1|AAH72453.2| 533|Homo sapiens TBC1 domain family, mem... 116 5e-25
BC063112-1|AAH63112.1| 622|Homo sapiens TBC1D10B protein protein. 116 5e-25
AK023192-1|BAB14454.1| 533|Homo sapiens protein ( Homo sapiens ... 116 5e-25
BC033712-1|AAH33712.1| 415|Homo sapiens TBC1D2B protein protein. 105 9e-22
AB028978-1|BAA83007.1| 868|Homo sapiens KIAA1055 protein protein. 103 2e-21
AL355341-2|CAH70583.2| 775|Homo sapiens TBC1 domain family, mem... 103 4e-21
AL138759-3|CAH70223.2| 775|Homo sapiens TBC1 domain family, mem... 103 4e-21
AB011180-1|BAA25534.1| 775|Homo sapiens KIAA0608 protein protein. 103 4e-21
CR456441-1|CAG30327.1| 749|Homo sapiens dJ1042K10.2 protein. 97 3e-19
BC041167-1|AAH41167.1| 678|Homo sapiens TBC1 domain family, mem... 97 3e-19
BC008078-1|AAH08078.1| 749|Homo sapiens RUN and TBC1 domain con... 97 3e-19
AY308849-1|AAQ81879.1| 749|Homo sapiens merlin binding protein ... 97 3e-19
AL833868-1|CAD38726.1| 381|Homo sapiens hypothetical protein pr... 97 3e-19
AL022238-3|CAA18266.1| 777|Homo sapiens protein ( Human DNA seq... 97 3e-19
AK000006-1|BAA92231.1| 401|Homo sapiens FLJ00006 protein protein. 97 3e-19
AB196956-1|BAE02561.1| 749|Homo sapiens Rab-GTPase-activating-p... 97 3e-19
AB037743-1|BAA92560.1| 702|Homo sapiens KIAA1322 protein protein. 97 3e-19
BC080640-1|AAH80640.1| 354|Homo sapiens Unknown (protein for IM... 95 7e-19
BC062461-1|AAH62461.1| 317|Homo sapiens GRTP1 protein protein. 95 7e-19
AL136221-9|CAI13799.2| 336|Homo sapiens growth hormone regulate... 95 7e-19
AL591849-3|CAI40161.1| 1178|Homo sapiens novel protein protein. 95 1e-18
AL391315-4|CAI39548.1| 1178|Homo sapiens novel protein protein. 95 1e-18
Z99127-4|CAI18934.1| 378|Homo sapiens RAB GTPase activating pro... 93 3e-18
BC071978-1|AAH71978.1| 502|Homo sapiens TBC1D2 protein protein. 93 3e-18
BC033071-1|AAH33071.2| 276|Homo sapiens GRTP1 protein protein. 93 3e-18
BC028918-1|AAH28918.1| 468|Homo sapiens TBC1D2 protein protein. 93 3e-18
AL360081-1|CAH71884.1| 710|Homo sapiens TBC1 domain family, mem... 93 3e-18
AL161671-3|CAI16278.1| 378|Homo sapiens RAB GTPase activating p... 93 3e-18
AL137073-10|CAI13894.1| 468|Homo sapiens TBC1 domain family, me... 93 3e-18
AL137073-1|CAI13883.1| 710|Homo sapiens TBC1 domain family, mem... 93 3e-18
AL136377-1|CAI22932.1| 378|Homo sapiens RAB GTPase activating p... 93 3e-18
AK026105-1|BAB15361.1| 710|Homo sapiens protein ( Homo sapiens ... 93 3e-18
AB019491-1|BAA77332.1| 378|Homo sapiens IDN4-GGTR8 protein. 93 3e-18
X63546-1|CAA45108.1| 786|Homo sapiens oncogene protein. 93 4e-18
AY143550-1|AAN38838.1| 1406|Homo sapiens ubiquitin-specific prot... 93 4e-18
Z99127-5|CAI18935.1| 377|Homo sapiens RAB GTPase activating pro... 93 5e-18
AL161671-4|CAI16279.1| 377|Homo sapiens RAB GTPase activating p... 93 5e-18
AL136377-2|CAI22933.1| 377|Homo sapiens RAB GTPase activating p... 93 5e-18
AB019489-1|BAA77330.1| 377|Homo sapiens IDN4-GGTR6 protein. 93 5e-18
AC016738-3|AAY14824.1| 897|Homo sapiens unknown protein. 92 7e-18
AB024057-1|BAA75489.1| 897|Homo sapiens vascular Rab-GAP/TBC-co... 92 7e-18
AB017114-1|BAA76517.1| 733|Homo sapiens AD 3 protein. 92 7e-18
X63547-1|CAA45110.1| 376|Homo sapiens oncogene protein. 92 9e-18
AK131086-1|BAC85136.1| 217|Homo sapiens FLJ00288 protein protein. 90 3e-17
AK127020-1|BAC86789.1| 1015|Homo sapiens protein ( Homo sapiens ... 90 4e-17
AB020689-1|BAA74905.2| 1291|Homo sapiens KIAA0882 protein protein. 90 4e-17
BC018630-1|AAH18630.2| 140|Homo sapiens RABGAP1L protein protein. 89 9e-17
BC129994-1|AAI29995.1| 1232|Homo sapiens TBC1 domain family, mem... 88 1e-16
AB014576-1|BAA31651.1| 1262|Homo sapiens KIAA0676 protein protein. 88 1e-16
BC071680-1|AAH71680.1| 549|Homo sapiens TBC1 domain family, mem... 87 3e-16
AF540953-1|AAN33117.1| 549|Homo sapiens Rab GTPase-activating p... 87 3e-16
BC058890-1|AAH58890.1| 346|Homo sapiens TBC1D3P2 protein protein. 86 5e-16
AK131449-1|BAD18594.1| 599|Homo sapiens d) (GAPCENA). protein. 85 8e-16
AK000173-1|BAA90990.1| 312|Homo sapiens protein ( Homo sapiens ... 84 2e-15
BC075809-1|AAH75809.1| 549|Homo sapiens TBC1 domain family, mem... 83 3e-15
BC078140-1|AAH78140.1| 291|Homo sapiens TBC1D3 protein protein. 82 1e-14
AL591502-1|CAI12579.1| 860|Homo sapiens TBC1 domain family, mem... 81 1e-14
AL360081-3|CAH71886.1| 860|Homo sapiens TBC1 domain family, mem... 81 1e-14
AL137073-2|CAI13884.1| 860|Homo sapiens TBC1 domain family, mem... 81 1e-14
BC112125-1|AAI12126.1| 257|Homo sapiens GRTP1 protein protein. 80 4e-14
BC112123-1|AAI12124.1| 257|Homo sapiens GRTP1 protein protein. 80 4e-14
AL136221-8|CAI13800.2| 266|Homo sapiens growth hormone regulate... 80 4e-14
AK026127-1|BAB15368.1| 257|Homo sapiens protein ( Homo sapiens ... 79 5e-14
BC050523-1|AAH50523.2| 385|Homo sapiens TBC1D10B protein protein. 79 9e-14
AK074954-1|BAC11312.1| 265|Homo sapiens protein ( Homo sapiens ... 79 9e-14
Z99127-6|CAI18936.1| 358|Homo sapiens RAB GTPase activating pro... 77 4e-13
AL161671-5|CAI16280.1| 358|Homo sapiens RAB GTPase activating p... 77 4e-13
AL136377-3|CAI22934.1| 358|Homo sapiens RAB GTPase activating p... 77 4e-13
AK091248-1|BAC03620.1| 340|Homo sapiens protein ( Homo sapiens ... 77 4e-13
AB019493-1|BAA77334.1| 358|Homo sapiens IDN4-GGTR9 protein. 77 4e-13
AB019492-1|BAA77333.2| 358|Homo sapiens IDN4-GGTR14 protein. 77 4e-13
AK123957-1|BAC85735.1| 632|Homo sapiens protein ( Homo sapiens ... 76 5e-13
AY026527-1|AAK07684.1| 917|Homo sapiens prostate antigen PARIS-... 75 8e-13
AL591502-2|CAI12580.1| 917|Homo sapiens TBC1 domain family, mem... 75 8e-13
AL360081-4|CAH71887.1| 917|Homo sapiens TBC1 domain family, mem... 75 8e-13
AL137073-3|CAI13885.1| 917|Homo sapiens TBC1 domain family, mem... 75 8e-13
BC122564-1|AAI22565.1| 632|Homo sapiens TBC1 domain family, mem... 75 1e-12
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 65 1e-09
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 65 1e-09
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 65 1e-09
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 65 1e-09
BC047400-1|AAH47400.1| 250|Homo sapiens hypothetical protein MG... 65 1e-09
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 65 1e-09
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 64 2e-09
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 64 2e-09
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 64 2e-09
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 64 2e-09
D11393-1|BAA01989.1| 208|Homo sapiens human non-muscle myosin h... 62 8e-09
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 61 2e-08
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 61 2e-08
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 61 2e-08
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 61 2e-08
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 61 2e-08
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 61 2e-08
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 60 3e-08
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 59 6e-08
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 59 6e-08
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 59 6e-08
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 59 6e-08
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 59 6e-08
AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein. 58 1e-07
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 58 2e-07
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 57 3e-07
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 57 3e-07
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 57 3e-07
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 57 3e-07
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 57 3e-07
Z99127-3|CAI18933.1| 370|Homo sapiens RAB GTPase activating pro... 56 7e-07
AL161671-2|CAI16277.1| 370|Homo sapiens RAB GTPase activating p... 56 7e-07
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 56 7e-07
AB007940-1|BAA32316.2| 413|Homo sapiens KIAA0471 protein protein. 56 7e-07
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 55 1e-06
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 55 1e-06
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 55 1e-06
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 55 1e-06
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 55 1e-06
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 55 1e-06
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 55 1e-06
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 55 1e-06
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 55 1e-06
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 55 1e-06
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 55 1e-06
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 54 2e-06
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 54 2e-06
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 54 3e-06
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 54 3e-06
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 54 3e-06
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 54 3e-06
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 54 3e-06
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 53 4e-06
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 53 4e-06
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 53 5e-06
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 53 5e-06
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 52 7e-06
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 52 9e-06
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 52 9e-06
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 52 9e-06
BX640704-1|CAE45824.1| 594|Homo sapiens hypothetical protein pr... 52 9e-06
BX530088-3|CAI95786.1| 841|Homo sapiens GRIP1 associated protei... 52 9e-06
BX530088-2|CAI95785.1| 796|Homo sapiens GRIP1 associated protei... 52 9e-06
BC101546-1|AAI01547.1| 841|Homo sapiens GRIP1 associated protei... 52 9e-06
BC101544-1|AAI01545.1| 841|Homo sapiens GRIP1 associated protei... 52 9e-06
BC001522-1|AAH01522.2| 557|Homo sapiens GRIPAP1 protein protein. 52 9e-06
AB032993-1|BAA86481.1| 834|Homo sapiens KIAA1167 protein protein. 52 9e-06
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 52 1e-05
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 52 1e-05
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 52 1e-05
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 52 1e-05
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 51 2e-05
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 51 2e-05
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 51 2e-05
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 51 2e-05
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 51 2e-05
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 51 2e-05
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 51 2e-05
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 51 2e-05
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 51 2e-05
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 51 2e-05
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 50 3e-05
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 50 3e-05
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 50 3e-05
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 50 3e-05
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 50 3e-05
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 50 3e-05
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 50 3e-05
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 50 3e-05
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 50 3e-05
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 50 4e-05
AL137265-1|CAB70664.1| 992|Homo sapiens hypothetical protein pr... 50 4e-05
AK125995-1|BAC86384.1| 842|Homo sapiens protein ( Homo sapiens ... 50 4e-05
AB028975-1|BAA83004.2| 1456|Homo sapiens KIAA1052 protein protein. 50 4e-05
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 50 4e-05
L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein. 50 5e-05
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 50 5e-05
BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for IM... 50 5e-05
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 50 5e-05
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2... 50 5e-05
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 49 6e-05
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 49 8e-05
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 49 8e-05
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 49 8e-05
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 49 8e-05
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 49 8e-05
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 49 8e-05
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 49 8e-05
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 49 8e-05
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 49 8e-05
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 49 8e-05
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 49 8e-05
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 49 8e-05
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 48 1e-04
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 48 1e-04
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 48 1e-04
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 48 1e-04
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 48 1e-04
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 48 1e-04
AL136093-3|CAI42825.1| 1285|Homo sapiens myosin VI protein. 48 1e-04
AL109897-3|CAI19521.1| 1285|Homo sapiens myosin VI protein. 48 1e-04
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 48 1e-04
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 48 1e-04
AB002387-1|BAA20843.2| 1296|Homo sapiens KIAA0389 protein. 48 1e-04
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 48 2e-04
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 48 2e-04
U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein. 48 2e-04
L16782-1|AAC37542.1| 566|Homo sapiens putative M phase phosphop... 48 2e-04
BC028366-1|AAH28366.1| 698|Homo sapiens testis specific, 10 pro... 48 2e-04
AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein. 48 2e-04
AF254756-1|AAK13079.1| 698|Homo sapiens predicted testis protei... 48 2e-04
AF229111-1|AAK00229.1| 1285|Homo sapiens myosin VI protein. 48 2e-04
AC019097-1|AAY14820.1| 698|Homo sapiens unknown protein. 48 2e-04
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 47 3e-04
BX530088-4|CAI95787.1| 625|Homo sapiens GRIP1 associated protei... 47 3e-04
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 47 3e-04
BC021134-1|AAH21134.1| 903|Homo sapiens centrobin, centrosomal ... 47 3e-04
BC014055-1|AAH14055.3| 805|Homo sapiens CNTROB protein protein. 47 3e-04
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 47 3e-04
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 47 3e-04
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 47 3e-04
AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein. 47 3e-04
AY160227-1|AAO22136.1| 925|Homo sapiens centrobin beta protein. 47 3e-04
AY160226-1|AAO22135.1| 903|Homo sapiens centrobin alpha protein. 47 3e-04
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 47 3e-04
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 47 3e-04
AL137068-4|CAI12357.1| 994|Homo sapiens centrosomal protein 110... 47 3e-04
AL137068-3|CAI12356.1| 828|Homo sapiens centrosomal protein 110... 47 3e-04
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 47 3e-04
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 47 3e-04
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 47 3e-04
AK024453-1|BAB15743.1| 272|Homo sapiens FLJ00045 protein protein. 47 3e-04
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 47 3e-04
AF331638-1|AAL56068.2| 903|Homo sapiens PP1221 protein. 47 3e-04
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 47 3e-04
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 47 3e-04
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 47 3e-04
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 47 3e-04
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 47 3e-04
BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, mem... 47 3e-04
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 47 3e-04
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 47 3e-04
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 47 3e-04
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 47 3e-04
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 47 3e-04
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 47 3e-04
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 47 3e-04
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 47 3e-04
AK022147-1|BAB13971.1| 674|Homo sapiens protein ( Homo sapiens ... 47 3e-04
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 47 3e-04
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 46 5e-04
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 46 5e-04
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 46 5e-04
AL590431-12|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 46 5e-04
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 46 5e-04
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 46 5e-04
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 46 5e-04
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 46 5e-04
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 46 5e-04
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 46 5e-04
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 46 5e-04
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 46 5e-04
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 46 5e-04
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 46 6e-04
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 46 6e-04
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 46 6e-04
BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein. 46 6e-04
BC068997-1|AAH68997.1| 541|Homo sapiens centrosomal protein 63k... 46 6e-04
BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting p... 46 6e-04
BC014109-1|AAH14109.1| 670|Homo sapiens leucine rich repeat con... 46 6e-04
BC012295-1|AAH12295.1| 586|Homo sapiens lamin B1 protein. 46 6e-04
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 46 6e-04
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 46 6e-04
AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 pro... 46 6e-04
AK124447-1|BAC85854.1| 434|Homo sapiens protein ( Homo sapiens ... 46 6e-04
AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens ... 46 6e-04
AK056465-1|BAB71192.1| 703|Homo sapiens protein ( Homo sapiens ... 46 6e-04
AK023448-1|BAB14578.1| 541|Homo sapiens protein ( Homo sapiens ... 46 6e-04
AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen... 46 6e-04
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 46 6e-04
AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein. 46 6e-04
Z97832-4|CAI20190.1| 631|Homo sapiens differentially expressed ... 46 8e-04
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 46 8e-04
M34458-1|AAA36162.1| 586|Homo sapiens protein ( Human lamin B m... 46 8e-04
L37747-1|AAC37575.1| 586|Homo sapiens lamin B1 protein. 46 8e-04
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 46 8e-04
BC103723-1|AAI03724.1| 586|Homo sapiens lamin B1 protein. 46 8e-04
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 46 8e-04
BC048304-1|AAH48304.1| 597|Homo sapiens HOOK3 protein protein. 46 8e-04
AY241694-1|AAO91767.1| 631|Homo sapiens IRF4-binding protein pr... 46 8e-04
AJ276095-1|CAC08450.1| 631|Homo sapiens Def-6 protein protein. 46 8e-04
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 46 8e-04
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 45 0.001
U53445-1|AAA98972.1| 752|Homo sapiens DOC1 protein. 45 0.001
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 45 0.001
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 45 0.001
BC115384-1|AAI15385.1| 684|Homo sapiens taxilin beta protein. 45 0.001
BC115383-1|AAI15384.1| 684|Homo sapiens taxilin beta protein. 45 0.001
AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kin... 45 0.001
AL834248-1|CAD38924.2| 715|Homo sapiens hypothetical protein pr... 45 0.001
AL831988-1|CAD91140.1| 718|Homo sapiens hypothetical protein pr... 45 0.001
AL592434-1|CAH73884.1| 684|Homo sapiens RP3-522B19.2 protein. 45 0.001
AL158850-1|CAI42896.1| 684|Homo sapiens RP3-522B19.2 protein. 45 0.001
AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens ... 45 0.001
AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK... 45 0.001
AC005035-1|AAY14969.1| 1260|Homo sapiens unknown protein. 45 0.001
AB085905-1|BAC92688.1| 684|Homo sapiens muscle-derived protein ... 45 0.001
AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein. 45 0.001
Z22664-1|CAA80377.1| 595|Homo sapiens membrane organizing prote... 45 0.001
Y18000-2|CAA76993.1| 615|Homo sapiens NF2 protein protein. 45 0.001
Y18000-1|CAA76992.1| 595|Homo sapiens NF2 protein protein. 45 0.001
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 45 0.001
X72655-1|CAA51220.1| 595|Homo sapiens schwannomin protein. 45 0.001
L11353-1|AAA36212.1| 595|Homo sapiens moesin-ezrin-radixin-like... 45 0.001
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 45 0.001
CR456530-1|CAG30416.1| 595|Homo sapiens NF2 protein. 45 0.001
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 45 0.001
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 45 0.001
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 45 0.001
BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein. 45 0.001
BC020257-1|AAH20257.1| 595|Homo sapiens neurofibromin 2 (bilate... 45 0.001
BC003112-1|AAH03112.2| 507|Homo sapiens neurofibromin 2 (bilate... 45 0.001
BC002700-1|AAH02700.1| 469|Homo sapiens keratin 7 protein. 45 0.001
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 45 0.001
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 45 0.001
AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens ... 45 0.001
AJ238246-1|CAB41416.1| 469|Homo sapiens sarcolectin protein. 45 0.001
AF509892-1|AAN64035.1| 469|Homo sapiens keratin 7 protein. 45 0.001
AF509887-1|AAN64031.1| 469|Homo sapiens keratin 7 protein. 45 0.001
AF369701-1|AAK54196.1| 590|Homo sapiens neurofibromatosis type ... 45 0.001
AF369665-1|AAK54166.1| 507|Homo sapiens neurofibromatosis type ... 45 0.001
AF369664-1|AAK54165.1| 549|Homo sapiens neurofibromatosis type ... 45 0.001
AF369663-1|AAK54164.1| 548|Homo sapiens neurofibromatosis type ... 45 0.001
AF369662-1|AAK54163.1| 590|Homo sapiens neurofibromatosis type ... 45 0.001
AF369661-1|AAK54162.1| 595|Homo sapiens neurofibromatosis type ... 45 0.001
AF369658-1|AAK54161.1| 590|Homo sapiens neurofibromatosis type ... 45 0.001
AF369657-1|AAK54160.1| 595|Homo sapiens neurofibromatosis type ... 45 0.001
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 45 0.001
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 45 0.001
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 45 0.001
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 45 0.001
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 45 0.001
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 44 0.002
X13320-1|CAA31695.1| 469|Homo sapiens keratin protein. 44 0.002
X03212-1|CAA26956.2| 489|Homo sapiens put. keratin K7 protein. 44 0.002
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 44 0.002
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 44 0.002
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 44 0.002
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 44 0.002
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 44 0.002
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 44 0.002
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 44 0.002
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 44 0.002
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 44 0.002
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 44 0.002
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 44 0.002
BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20 ... 44 0.002
BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20 ... 44 0.002
BC041888-1|AAH41888.1| 605|Homo sapiens RABGAP1L protein protein. 44 0.002
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 44 0.002
AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20 ... 44 0.002
AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20 ... 44 0.002
AL157958-1|CAB76100.1| 582|Homo sapiens hypothetical protein pr... 44 0.002
AL031286-2|CAI22381.1| 605|Homo sapiens RAB GTPase activating p... 44 0.002
AL031286-1|CAI22380.1| 582|Homo sapiens RAB GTPase activating p... 44 0.002
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 44 0.002
AL022400-3|CAI22877.1| 605|Homo sapiens RAB GTPase activating p... 44 0.002
AL022400-2|CAI22876.1| 582|Homo sapiens RAB GTPase activating p... 44 0.002
AL022400-1|CAI22875.1| 252|Homo sapiens RAB GTPase activating p... 44 0.002
AL022171-3|CAI20383.1| 605|Homo sapiens RAB GTPase activating p... 44 0.002
AL022171-2|CAI20382.1| 582|Homo sapiens RAB GTPase activating p... 44 0.002
AL022171-1|CAI20381.1| 252|Homo sapiens RAB GTPase activating p... 44 0.002
AL021069-2|CAI23486.1| 605|Homo sapiens RAB GTPase activating p... 44 0.002
AL021069-1|CAI23485.1| 252|Homo sapiens RAB GTPase activating p... 44 0.002
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK002051-1|BAA92057.1| 333|Homo sapiens protein ( Homo sapiens ... 44 0.002
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 44 0.002
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 44 0.002
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 44 0.002
AB058696-1|BAB47422.1| 1270|Homo sapiens KIAA1793 protein protein. 44 0.002
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 44 0.002
U90236-1|AAC51654.2| 1262|Homo sapiens myosin VI protein. 44 0.002
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 44 0.002
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 44 0.002
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 44 0.002
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 44 0.002
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 44 0.002
BC023021-1|AAH23021.1| 731|Homo sapiens golgi autoantigen, golg... 44 0.002
BC014983-1|AAH14983.1| 403|Homo sapiens TBC1D20 protein protein. 44 0.002
AY644768-1|AAV85456.1| 731|Homo sapiens cell proliferation-indu... 44 0.002
AL442071-4|CAH73671.1| 5938|Homo sapiens microtubule-actin cross... 44 0.002
AL442071-2|CAH73669.1| 4433|Homo sapiens microtubule-actin cross... 44 0.002
AL442071-1|CAH73668.1| 5430|Homo sapiens microtubule-actin cross... 44 0.002
AL365277-12|CAI16422.1| 5938|Homo sapiens microtubule-actin cros... 44 0.002
AL365277-10|CAI16420.1| 4433|Homo sapiens microtubule-actin cros... 44 0.002
AL365277-7|CAI16417.1| 5430|Homo sapiens microtubule-actin cross... 44 0.002
AL355477-1|CAH70156.1| 5430|Homo sapiens microtubule-actin cross... 44 0.002
AL137853-3|CAI21816.1| 5938|Homo sapiens microtubule-actin cross... 44 0.002
AL137853-2|CAI21815.1| 4433|Homo sapiens microtubule-actin cross... 44 0.002
AL137853-1|CAI21814.1| 5430|Homo sapiens microtubule-actin cross... 44 0.002
AL136093-4|CAI42826.1| 1253|Homo sapiens myosin VI protein. 44 0.002
AL136093-2|CAI42824.1| 1262|Homo sapiens myosin VI protein. 44 0.002
AL121747-1|CAI23015.1| 403|Homo sapiens TBC1 domain family, mem... 44 0.002
AL109897-2|CAI19522.1| 1253|Homo sapiens myosin VI protein. 44 0.002
AL109897-1|CAI19520.1| 1262|Homo sapiens myosin VI protein. 44 0.002
AL049761-1|CAI23048.1| 403|Homo sapiens TBC1 domain family, mem... 44 0.002
AJ132949-1|CAB36967.1| 585|Homo sapiens rfg5 protein protein. 44 0.002
AF325341-2|AAL38997.1| 5314|Homo sapiens macrophin 1 isoform 4 p... 44 0.002
AF325341-1|AAL39000.1| 4631|Homo sapiens macrophin 1 isoform 2 p... 44 0.002
AF317696-1|AAL09459.1| 5938|Homo sapiens macrophin 1 isoform 4 p... 44 0.002
AF141968-1|AAF06360.1| 5373|Homo sapiens trabeculin-alpha protein. 44 0.002
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 44 0.002
AF085199-1|AAD09753.1| 731|Homo sapiens golgin-84 protein. 44 0.002
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 44 0.002
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 44 0.002
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 44 0.002
AB029290-1|BAA83821.1| 5430|Homo sapiens actin binding protein A... 44 0.002
AB007934-1|BAA32310.3| 4433|Homo sapiens KIAA0465 protein protein. 44 0.002
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 44 0.002
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 44 0.003
AF282265-1|AAF87584.1| 919|Homo sapiens inner centromere protei... 44 0.003
AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20 ... 44 0.003
AF223939-1|AAK00630.1| 2073|Homo sapiens ninein isotype 3 protein. 44 0.003
AF223938-1|AAK00629.1| 2069|Homo sapiens ninein isotype 2 protein. 44 0.003
AF223937-1|AAK00628.1| 2029|Homo sapiens ninein isotype 1 protein. 44 0.003
AB252981-1|BAF48798.1| 506|Homo sapiens Nef-associated factor 1... 44 0.003
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 44 0.003
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 43 0.004
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 43 0.004
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 43 0.004
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 43 0.004
AY834276-1|AAV97884.1| 1042|Homo sapiens mitogen-activated prote... 43 0.004
AY736182-1|AAU86898.1| 1989|Homo sapiens ninein isoform 6 protein. 43 0.004
AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein. 43 0.004
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 43 0.004
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 43 0.004
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 43 0.004
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 43 0.004
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 43 0.006
U39403-1|AAC99999.1| 500|Homo sapiens protein ( Human fetal cra... 43 0.006
D30755-1|BAA06416.2| 636|Homo sapiens KIAA0113 protein. 43 0.006
BX530088-1|CAI95784.1| 810|Homo sapiens GRIP1 associated protei... 43 0.006
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 43 0.006
BC050548-1|AAH50548.1| 1127|Homo sapiens KIF4A protein protein. 43 0.006
BC036947-1|AAH36947.1| 405|Homo sapiens TBC1D16 protein protein. 43 0.006
BC030802-1|AAH30802.2| 661|Homo sapiens Similar to ring finger ... 43 0.006
BC028290-1|AAH28290.1| 767|Homo sapiens TBC1 domain family, mem... 43 0.006
BC018647-1|AAH18647.1| 1001|Homo sapiens ring finger protein 40 ... 43 0.006
BC014008-1|AAH14008.1| 636|Homo sapiens TNIP1 protein protein. 43 0.006
BC012133-1|AAH12133.1| 636|Homo sapiens TNFAIP3 interacting pro... 43 0.006
BC011769-1|AAH11769.1| 1001|Homo sapiens ring finger protein 40 ... 43 0.006
BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein. 43 0.006
BC006133-1|AAH06133.1| 1001|Homo sapiens ring finger protein 40 ... 43 0.006
BC001525-1|AAH01525.2| 300|Homo sapiens TBC1D16 protein protein. 43 0.006
AL357752-3|CAI41487.1| 1232|Homo sapiens kinesin family member 4... 43 0.006
AL139398-5|CAI41024.1| 1232|Homo sapiens kinesin family member 4... 43 0.006
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 43 0.006
AK127062-1|BAC86808.1| 428|Homo sapiens protein ( Homo sapiens ... 43 0.006
AK027406-1|BAB55092.1| 901|Homo sapiens protein ( Homo sapiens ... 43 0.006
AJ271784-1|CAB75427.1| 1232|Homo sapiens chromokinesin protein. 43 0.006
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 43 0.006
AJ011896-1|CAA09856.1| 635|Homo sapiens Naf1 beta protein protein. 43 0.006
>BC014111-1|AAH14111.1| 794|Homo sapiens ecotropic viral
integration site 5-like protein.
Length = 794
Score = 530 bits (1309), Expect = e-150
Identities = 301/747 (40%), Positives = 433/747 (57%), Gaps = 67/747 (8%)
Query: 99 SETIPTPDRALLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEVETR 158
SE + + LLAKLEE+NR +EAD+K+ R H
Sbjct: 27 SENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHL---- 82
Query: 159 PTPGTNGEEDLWSLWGRLVSNWESEWKRRNQ-WVRDLVRQGVPHHFRGIVWQLLAGVDTS 217
EED W LWGR+ + WE EW+RR + +++L+R+G+PHHFR IVWQLL
Sbjct: 83 -------EEDTWILWGRIANEWE-EWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDM 134
Query: 218 PEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVG 277
P K Y+ +K S CEK+IRRDIARTYPEH+FFK +D LGQE LFNVMKAYSL DREVG
Sbjct: 135 PVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVG 194
Query: 278 YCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELL 337
YCQGS FIVGLLLMQMPEEEAF V V++MQ++R+R++FKPSMAELGLC++Q E ++QE L
Sbjct: 195 YCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQL 254
Query: 338 PDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTL 397
PDL+ HF+SQSF TS+YA P+A R+ D+F+ EG+EIVF+V LALL +
Sbjct: 255 PDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQV 314
Query: 398 GKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
+ +L+ LDME + +Y Q+ +P + ++ + AY VK NPKKMK+LEKEY +K+KE
Sbjct: 315 NQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKE 374
Query: 458 QGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALR 517
+ ++ LR ENRLLKQR+ +GQV RA+ EE + + RE+ +R
Sbjct: 375 MEEQIEIKRLRTENRLLKQRIETLE-----------KGQVTRAQEAEENYVIKRELAVVR 423
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
Q+ + A ++++ + TI + +Q + TE EL +
Sbjct: 424 -------QQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQ--------SR 468
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+ ++E N SL +NNVA LQ+EL A+K+RE +A S ++L
Sbjct: 469 LRETETLGALREMQDKVLDMEKRNSSLPD---ENNVAQLQEELKALKVREGQAVASTREL 525
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
+ ++ ELS++WQ HL + +P+KL+ + +L +EL
Sbjct: 526 KLQLQELSDTWQAHLARGGR--------------WKESPRKLV---------VGELQDEL 562
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQ 757
M+ R+RE +AL E +ELR +V+ELETQ + N L R + E L+E L + + LQ
Sbjct: 563 MSVRLREAQALAEGRELRQRVVELETQDHIHRNLLNRVEAERAALQEKLQYLAAQNKGLQ 622
Query: 758 TRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRN 817
T+ E + K A+ E K+K E M +R + +AE+ ++E +++ E +G+L
Sbjct: 623 TQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQL-- 680
Query: 818 NNMDDSDRVRELQEQVAELKAEIMRLE 844
N+ D S +REL++Q+ ELKAE+ L+
Sbjct: 681 NHSDSSQYIRELKDQIEELKAEVRLLK 707
Score = 41.1 bits (92), Expect = 0.017
Identities = 67/273 (24%), Positives = 116/273 (42%), Gaps = 36/273 (13%)
Query: 616 LQDELIAVKLREAEANLSLKDLR-------QRVSELSESWQRHLQEH------KQEAPAA 662
L+ E A+K +E E + +K LR QR+ L + QE K+E
Sbjct: 363 LEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKGQVTRAQEAEENYVIKRELAVV 422
Query: 663 PVQ-SNVVSDIMATPKKLLRAWEGRSADMLK------LDEELMTTRIREVEALTELKELR 715
Q S+ D+ + + E + L L+ EL +R+RE E L L+E++
Sbjct: 423 RQQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQ 482
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
KV+++E + N + L+E L A RE RE + + +L
Sbjct: 483 DKVLDMEKR-----NSSLPDENNVAQLQEELKALKVREGQAVASTRELKLQLQELSD--T 535
Query: 776 YESMQANIRNMEDAQR---IAELETEVSEYKLKNEVMATEG-ELRNN--NMDDSDRV-RE 828
+++ A +++ R + EL+ E+ +L+ EG ELR ++ D + R
Sbjct: 536 WQAHLARGGRWKESPRKLVVGELQDELMSVRLREAQALAEGRELRQRVVELETQDHIHRN 595
Query: 829 LQEQV-AELKAEIMRLEAWKSRALG-HTELSRA 859
L +V AE A +L+ ++ G T+LS +
Sbjct: 596 LLNRVEAERAALQEKLQYLAAQNKGLQTQLSES 628
>AL354890-2|CAI21914.1| 810|Homo sapiens ecotropic viral
integration site 5 protein.
Length = 810
Score = 448 bits (1105), Expect = e-125
Identities = 269/676 (39%), Positives = 367/676 (54%), Gaps = 40/676 (5%)
Query: 97 PTSETIPTPDRA-LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEV 155
P+S + +PD LLAKLEE+NR +E D+K+ R H
Sbjct: 72 PSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHL- 130
Query: 156 ETRPTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD 215
EED W LWGR+V+ WE K++ + V++LV +G+PHHFR IVWQLL
Sbjct: 131 ----------EEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQ 180
Query: 216 TSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
+ P K Y+ +K S CEK+IRRDIARTYPEH+FFKEKD LGQE LFNVMKAYSL DRE
Sbjct: 181 SMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRE 240
Query: 276 VGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQE 335
VGYCQGS FIVGLLLMQMPEEEAF V VK+MQ +R+R++FKPSMAELGLCM+Q E ++QE
Sbjct: 241 VGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQE 300
Query: 336 LLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
LP+L VHFQSQSF TS+YA P+A RI D+F+SEG+EIVF+V LALL
Sbjct: 301 HLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALL 360
Query: 396 TLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
+ + +L+ LDME +L++ QK +P + + + AY VK N KKMKKLEKEYT IKT
Sbjct: 361 QMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKT 420
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
KE + ++ LR ENRLLKQR+ + + E+ L++E+
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLE-----------KHKCSSNYNEDFVLQLEKELVQ 469
Query: 516 LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXX 575
R + + Q L D++ +E R +SL E+ + EEL
Sbjct: 470 ARLSEAESQCALKEMQDKVLDIE-------KRNNSLP-DENNIARLQEELIAVKLREAEA 521
Query: 576 XXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLK 635
L + N + LQDEL+ ++LREAE ++
Sbjct: 522 IMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIR 581
Query: 636 DLRQRVSELSESWQ---RHLQEHKQEAPAAPVQSNVVS-DIMATPKKLLRAWEGRSADML 691
+++QR+ E+ Q HL+ +QE + + +S +L A ++
Sbjct: 582 EIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIEC 641
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVS--TNQLRRQDEEARL--LRENLD 747
K EE+M R+RE +++ + ELR + ELE Q + QL + D + L++ +
Sbjct: 642 KNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQI- 700
Query: 748 AALQRERALQTRQREF 763
A L E QR F
Sbjct: 701 AELNHELRCLKGQRGF 716
Score = 146 bits (354), Expect = 3e-34
Identities = 90/249 (36%), Positives = 140/249 (56%), Gaps = 27/249 (10%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
++E N SL + NN+A LQ+ELIAVKLREAEA + LK+LRQ+V +L E WQRHL
Sbjct: 490 DIEKRNNSLPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHL--- 543
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+ PKK M +L +ELMT R+RE E E++E++
Sbjct: 544 ----------ARTTGRWKDPPKK---------NAMNELQDELMTIRLREAETQAEIREIK 584
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ME+ETQ Q+++N LRR ++E L+E + + + L T+ E + K A++E K K
Sbjct: 585 QRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNK 644
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
E M +R + +AEL ++E +++ E +G+L N D + + EL++Q+AE
Sbjct: 645 EEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQL--NKSDSNQYIGELKDQIAE 702
Query: 836 LKAEIMRLE 844
L E+ L+
Sbjct: 703 LNHELRCLK 711
Score = 49.2 bits (112), Expect = 6e-05
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 690 MLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAA 749
+L+L++EL+ R+ E E+ LKE++ KV+++E + N L ++ AR L+E L A
Sbjct: 460 VLQLEKELVQARLSEAESQCALKEMQDKVLDIEKR----NNSLPDENNIAR-LQEELIAV 514
Query: 750 LQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA--ELETEVSEYKLK-- 805
RE +E + + DLE + + R + ++ A EL+ E+ +L+
Sbjct: 515 KLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREA 574
Query: 806 ------NEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSRA 859
E+ E+ N +S+ +R +++V L+ ++ L A L T+LS A
Sbjct: 575 ETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLL--TQLSEA 632
Score = 42.3 bits (95), Expect = 0.007
Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 13/207 (6%)
Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW---EGRSADMLKLDEELMTTRIREV 705
Q L + E Q + P KL++A + S M KL++E T + +E+
Sbjct: 364 QAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEM 423
Query: 706 EALTELKEL----RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
E E+K L RL +ET + + +D +L +E + A L E Q +
Sbjct: 424 EEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLS-EAESQCALK 482
Query: 762 EFQHKYADLESKAKYESMQANIRNMED---AQRIAELETEVSEYKLKNEVMATEGELRNN 818
E Q K D+E + + NI +++ A ++ E E + +L+ +V E + +
Sbjct: 483 EMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRH 542
Query: 819 NMDDSDRVRELQEQVA--ELKAEIMRL 843
+ R ++ ++ A EL+ E+M +
Sbjct: 543 LARTTGRWKDPPKKNAMNELQDELMTI 569
>AL133332-1|CAC19437.2| 810|Homo sapiens ecotropic viral
integration site 5 protein.
Length = 810
Score = 448 bits (1105), Expect = e-125
Identities = 269/676 (39%), Positives = 367/676 (54%), Gaps = 40/676 (5%)
Query: 97 PTSETIPTPDRA-LLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEV 155
P+S + +PD LLAKLEE+NR +E D+K+ R H
Sbjct: 72 PSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHL- 130
Query: 156 ETRPTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD 215
EED W LWGR+V+ WE K++ + V++LV +G+PHHFR IVWQLL
Sbjct: 131 ----------EEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQ 180
Query: 216 TSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
+ P K Y+ +K S CEK+IRRDIARTYPEH+FFKEKD LGQE LFNVMKAYSL DRE
Sbjct: 181 SMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRE 240
Query: 276 VGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQE 335
VGYCQGS FIVGLLLMQMPEEEAF V VK+MQ +R+R++FKPSMAELGLCM+Q E ++QE
Sbjct: 241 VGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQE 300
Query: 336 LLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
LP+L VHFQSQSF TS+YA P+A RI D+F+SEG+EIVF+V LALL
Sbjct: 301 HLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALL 360
Query: 396 TLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
+ + +L+ LDME +L++ QK +P + + + AY VK N KKMKKLEKEYT IKT
Sbjct: 361 QMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKT 420
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
KE + ++ LR ENRLLKQR+ + + E+ L++E+
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLE-----------KHKCSSNYNEDFVLQLEKELVQ 469
Query: 516 LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXX 575
R + + Q L D++ +E R +SL E+ + EEL
Sbjct: 470 ARLSEAESQCALKEMQDKVLDIE-------KRNNSLP-DENNIARLQEELIAVKLREAEA 521
Query: 576 XXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLK 635
L + N + LQDEL+ ++LREAE ++
Sbjct: 522 IMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIR 581
Query: 636 DLRQRVSELSESWQ---RHLQEHKQEAPAAPVQSNVVS-DIMATPKKLLRAWEGRSADML 691
+++QR+ E+ Q HL+ +QE + + +S +L A ++
Sbjct: 582 EIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIEC 641
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVS--TNQLRRQDEEARL--LRENLD 747
K EE+M R+RE +++ + ELR + ELE Q + QL + D + L++ +
Sbjct: 642 KNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQI- 700
Query: 748 AALQRERALQTRQREF 763
A L E QR F
Sbjct: 701 AELNHELRCLKGQRGF 716
Score = 146 bits (354), Expect = 3e-34
Identities = 90/249 (36%), Positives = 140/249 (56%), Gaps = 27/249 (10%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
++E N SL + NN+A LQ+ELIAVKLREAEA + LK+LRQ+V +L E WQRHL
Sbjct: 490 DIEKRNNSLPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHL--- 543
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+ PKK M +L +ELMT R+RE E E++E++
Sbjct: 544 ----------ARTTGRWKDPPKK---------NAMNELQDELMTIRLREAETQAEIREIK 584
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ME+ETQ Q+++N LRR ++E L+E + + + L T+ E + K A++E K K
Sbjct: 585 QRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNK 644
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
E M +R + +AEL ++E +++ E +G+L N D + + EL++Q+AE
Sbjct: 645 EEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQL--NKSDSNQYIGELKDQIAE 702
Query: 836 LKAEIMRLE 844
L E+ L+
Sbjct: 703 LNHELRCLK 711
Score = 49.2 bits (112), Expect = 6e-05
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 690 MLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAA 749
+L+L++EL+ R+ E E+ LKE++ KV+++E + N L ++ AR L+E L A
Sbjct: 460 VLQLEKELVQARLSEAESQCALKEMQDKVLDIEKR----NNSLPDENNIAR-LQEELIAV 514
Query: 750 LQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA--ELETEVSEYKLK-- 805
RE +E + + DLE + + R + ++ A EL+ E+ +L+
Sbjct: 515 KLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREA 574
Query: 806 ------NEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSRA 859
E+ E+ N +S+ +R +++V L+ ++ L A L T+LS A
Sbjct: 575 ETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLL--TQLSEA 632
Score = 42.3 bits (95), Expect = 0.007
Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 13/207 (6%)
Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW---EGRSADMLKLDEELMTTRIREV 705
Q L + E Q + P KL++A + S M KL++E T + +E+
Sbjct: 364 QAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEM 423
Query: 706 EALTELKEL----RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
E E+K L RL +ET + + +D +L +E + A L E Q +
Sbjct: 424 EEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLS-EAESQCALK 482
Query: 762 EFQHKYADLESKAKYESMQANIRNMED---AQRIAELETEVSEYKLKNEVMATEGELRNN 818
E Q K D+E + + NI +++ A ++ E E + +L+ +V E + +
Sbjct: 483 EMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRH 542
Query: 819 NMDDSDRVRELQEQVA--ELKAEIMRL 843
+ R ++ ++ A EL+ E+M +
Sbjct: 543 LARTTGRWKDPPKKNAMNELQDELMTI 569
>AF008915-1|AAC16031.1| 810|Homo sapiens EVI-5 homolog protein.
Length = 810
Score = 442 bits (1090), Expect = e-123
Identities = 260/647 (40%), Positives = 355/647 (54%), Gaps = 37/647 (5%)
Query: 97 PTSETIPTPD-RALLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEV 155
P+S + +PD LLAKLEE+N +E D+K+ R H
Sbjct: 72 PSSPSQLSPDVLELLAKLEEQNILLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHL- 130
Query: 156 ETRPTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD 215
EED W LWGR+V+ WE K++ + V++LV +G+PHHFR IVWQLL
Sbjct: 131 ----------EEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQ 180
Query: 216 TSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
+ P K Y+ +K S CEK+IRRDIARTYPEH+FFKEKD LGQE LFNVMKAYSL DRE
Sbjct: 181 SMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRE 240
Query: 276 VGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQE 335
VGYCQGS FIVGLLLMQMPEEEAF V VK+MQ +R+R++FKPSMAELGLCM+Q E ++QE
Sbjct: 241 VGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQE 300
Query: 336 LLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
LP+L VHFQSQSF TS+YA P+A RI D+F+SEG+EIVF+V LALL
Sbjct: 301 HLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPVATRIFDIFMSEGLEIVFRVGLALL 360
Query: 396 TLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
+ + +L+ LDME +L++ QK +P + + + AY V+ N KKMKKLEKEYT IKT
Sbjct: 361 QMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVQYNSKKMKKLEKEYTTIKT 420
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
KE + ++ LR ENRLLKQR+ + + E+ L++E+
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLE-----------KHKCSSNYNEDFVLQLEKELVQ 469
Query: 516 LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXX 575
R + + Q L D++ +E R +SL E+ + EEL
Sbjct: 470 ARLSEAESQCALKEMQDKVLDIE-------KRNNSLP-DENNIARLQEELIAVKLREAEA 521
Query: 576 XXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLK 635
L + N + LQDEL+ ++LREAE ++
Sbjct: 522 IMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIR 581
Query: 636 DLRQRVSELSESWQ---RHLQEHKQEAPAAPVQSNVVS-DIMATPKKLLRAWEGRSADML 691
+++QR+ E+ Q HL+ +QE + + +S +L A ++
Sbjct: 582 EIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIEC 641
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVS--TNQLRRQD 736
K EE+M R+RE +++ + ELR + ELE Q + QL + D
Sbjct: 642 KNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSD 688
Score = 147 bits (357), Expect = 1e-34
Identities = 91/252 (36%), Positives = 141/252 (55%), Gaps = 27/252 (10%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
++E N SL + NN+A LQ+ELIAVKLREAEA + LK+LRQ+V +L E WQRHL
Sbjct: 490 DIEKRNNSLPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHL--- 543
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+ PKK M +L +ELMT R+RE E E++E++
Sbjct: 544 ----------ARTTGRWKDPPKKNA---------MNELQDELMTIRLREAETQAEIREIK 584
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ME+ETQ Q+++N LRR ++E L+E + + + L T+ E + K A++E K K
Sbjct: 585 QRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNK 644
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
E M +R + +AEL ++E +++ E +G+L N D + + EL++Q+AE
Sbjct: 645 EEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQL--NKSDSNQYIGELKDQIAE 702
Query: 836 LKAEIMRLEAWK 847
L E+ L+ K
Sbjct: 703 LNHELRCLKGQK 714
Score = 49.2 bits (112), Expect = 6e-05
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 690 MLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAA 749
+L+L++EL+ R+ E E+ LKE++ KV+++E + N L ++ AR L+E L A
Sbjct: 460 VLQLEKELVQARLSEAESQCALKEMQDKVLDIEKR----NNSLPDENNIAR-LQEELIAV 514
Query: 750 LQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA--ELETEVSEYKLK-- 805
RE +E + + DLE + + R + ++ A EL+ E+ +L+
Sbjct: 515 KLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREA 574
Query: 806 ------NEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSRA 859
E+ E+ N +S+ +R +++V L+ ++ L A L T+LS A
Sbjct: 575 ETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLL--TQLSEA 632
Score = 42.7 bits (96), Expect = 0.006
Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 13/207 (6%)
Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW---EGRSADMLKLDEELMTTRIREV 705
Q L + E Q + P KL++A + S M KL++E T + +E+
Sbjct: 364 QAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVQYNSKKMKKLEKEYTTIKTKEM 423
Query: 706 EALTELKEL----RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
E E+K L RL +ET + + +D +L +E + A L E Q +
Sbjct: 424 EEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLS-EAESQCALK 482
Query: 762 EFQHKYADLESKAKYESMQANIRNMED---AQRIAELETEVSEYKLKNEVMATEGELRNN 818
E Q K D+E + + NI +++ A ++ E E + +L+ +V E + +
Sbjct: 483 EMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRH 542
Query: 819 NMDDSDRVRELQEQVA--ELKAEIMRL 843
+ R ++ ++ A EL+ E+M +
Sbjct: 543 LARTTGRWKDPPKKNAMNELQDELMTI 569
>AF042345-1|AAC16041.1| 607|Homo sapiens truncated EVI5 protein.
Length = 607
Score = 422 bits (1039), Expect = e-117
Identities = 235/549 (42%), Positives = 313/549 (57%), Gaps = 31/549 (5%)
Query: 97 PTSETIPTPD-RALLAKLEEENRRIEADAKNASLTTVHSRKXXXXXXXXXXXXXXXXHEV 155
P+S + +PD LLAKLEE+N +E D+K+ R H
Sbjct: 72 PSSPSQLSPDVLELLAKLEEQNILLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHL- 130
Query: 156 ETRPTPGTNGEEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVD 215
EED W LWGR+V+ WE K++ + V++LV +G+PHHFR IVWQLL
Sbjct: 131 ----------EEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQ 180
Query: 216 TSPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDRE 275
+ P K Y+ +K S CEK+IRRDIARTYPEH+FFKEKD LGQE LFNVMKAYSL DRE
Sbjct: 181 SMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRE 240
Query: 276 VGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQE 335
VGYCQGS FIVGLLLMQMPEEEAF V VK+MQ +R+R++FKPSMAELGLCM+Q E ++QE
Sbjct: 241 VGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQE 300
Query: 336 LLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
LP+L VHFQSQSF TS+YA P+A RI D+F+SEG+EIVF+V LALL
Sbjct: 301 HLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPVATRIFDIFMSEGLEIVFRVGLALL 360
Query: 396 TLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
+ + +L+ LDME +L++ QK +P + + + AY V+ N KKMKKLEKEYT IKT
Sbjct: 361 QMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVQYNSKKMKKLEKEYTTIKT 420
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
KE + ++ LR ENRLLKQR+ + + E+ L++E+
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLE-----------KHKCSSNYNEDFVLQLEKELVQ 469
Query: 516 LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXX 575
R + + Q L D++ +E R +SL E+ + EEL
Sbjct: 470 ARLSEAESQCALKEMQDKVLDIE-------KRNNSLP-DENNIARLQEELIAVKLREAEA 521
Query: 576 XXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLK 635
L + N + LQDEL+ ++LREAE ++
Sbjct: 522 IMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIR 581
Query: 636 DLRQRVSEL 644
+++QR+ E+
Sbjct: 582 EIKQRMMEM 590
Score = 84.2 bits (199), Expect = 2e-15
Identities = 55/135 (40%), Positives = 77/135 (57%), Gaps = 25/135 (18%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
++E N SL + NN+A LQ+ELIAVKLREAEA + LK+LRQ+V +L E WQRHL
Sbjct: 490 DIEKRNNSLPDE---NNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHL--- 543
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+ PKK M +L +ELMT R+RE E E++E++
Sbjct: 544 ----------ARTTGRWKDPPKK---------NAMNELQDELMTIRLREAETQAEIREIK 584
Query: 716 LKVMELETQVQVSTN 730
++ME+ETQ+ S +
Sbjct: 585 QRMMEMETQLVESAD 599
Score = 42.7 bits (96), Expect = 0.006
Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 13/207 (6%)
Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW---EGRSADMLKLDEELMTTRIREV 705
Q L + E Q + P KL++A + S M KL++E T + +E+
Sbjct: 364 QAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVQYNSKKMKKLEKEYTTIKTKEM 423
Query: 706 EALTELKEL----RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
E E+K L RL +ET + + +D +L +E + A L E Q +
Sbjct: 424 EEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLS-EAESQCALK 482
Query: 762 EFQHKYADLESKAKYESMQANIRNMED---AQRIAELETEVSEYKLKNEVMATEGELRNN 818
E Q K D+E + + NI +++ A ++ E E + +L+ +V E + +
Sbjct: 483 EMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRH 542
Query: 819 NMDDSDRVRELQEQVA--ELKAEIMRL 843
+ R ++ ++ A EL+ E+M +
Sbjct: 543 LARTTGRWKDPPKKNAMNELQDELMTI 569
Score = 39.5 bits (88), Expect = 0.052
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 18/184 (9%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
E+E E ++R R +N + L+ + ++ + +N + + Q EL Q L E
Sbjct: 422 EME-EQVEIKRLRTENRL--LKQRIETLEKHKCSSNYNEDFVLQLEKELV---QARLSEA 475
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+ + +Q V+ DI L ++ +L EEL+ ++RE EA+ LKELR
Sbjct: 476 ESQCALKEMQDKVL-DIEKRNNSL-----PDENNIARLQEELIAVKLREAEAIMGLKELR 529
Query: 716 LKVMELET--QVQVSTNQLRRQDEEAR----LLRENLDAALQRERALQTRQREFQHKYAD 769
+V +LE Q ++ R +D + L++ L RE Q RE + + +
Sbjct: 530 QQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMME 589
Query: 770 LESK 773
+E++
Sbjct: 590 METQ 593
>BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein.
Length = 997
Score = 251 bits (615), Expect = 7e-66
Identities = 140/401 (34%), Positives = 215/401 (53%), Gaps = 8/401 (1%)
Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK-KLYAS 225
E + WG L+S W R + + LVR GVP RG VWQLLAG + + Y
Sbjct: 463 EKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRI 522
Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
I +S + I RDI RT+P HD+FK+ G GQ+SL+ + KAYS++D E+GYCQG F+
Sbjct: 523 LITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFL 582
Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
+LL+ MPEE+AF+VLVKIM + +R++FK + +L +QLE L+QE +PDL+ HF
Sbjct: 583 AAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFL 642
Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
S +YA + I+D+ L EGI ++F VAL LL K+DLL
Sbjct: 643 DISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLT 702
Query: 406 DMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAV 463
D E LK+ + +LP + +++ A M LA ++K++ KK+KK EKEY ++ ++
Sbjct: 703 DFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDP 762
Query: 464 LRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFALDREVQALRRA 519
+ +ENR L++ V ++ D EE+ AL++E+ ++
Sbjct: 763 IERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQK 822
Query: 520 NVDMQQRLAVALDEIRSL-EMTIAENNSRQSSLEGTESASG 559
+D ++ +E L EM E + +S ++ S G
Sbjct: 823 LIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIG 863
Score = 35.1 bits (77), Expect = 1.1
Identities = 32/135 (23%), Positives = 68/135 (50%), Gaps = 9/135 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH-KYADLESKAK 775
K+MEL +++S +L++ ++E +RE Q+E ++ +RE + + A++ + +
Sbjct: 727 KLMELACNMKISQKKLKKYEKEYHTMREQ---QAQQEDPIERFERENRRLQEANMRLEQE 783
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
+ + + + A R E L E++ T+ +L +D + R L+E+ A+
Sbjct: 784 NDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKL----IDAEEEKRRLEEESAQ 839
Query: 836 LKAEIMRLEAWKSRA 850
LK E+ R E K+ +
Sbjct: 840 LK-EMCRRELDKAES 853
>AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating
protein 1 protein.
Length = 997
Score = 251 bits (615), Expect = 7e-66
Identities = 140/401 (34%), Positives = 215/401 (53%), Gaps = 8/401 (1%)
Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK-KLYAS 225
E + WG L+S W R + + LVR GVP RG VWQLLAG + + Y
Sbjct: 463 EKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRI 522
Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
I +S + I RDI RT+P HD+FK+ G GQ+SL+ + KAYS++D E+GYCQG F+
Sbjct: 523 LITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFL 582
Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
+LL+ MPEE+AF+VLVKIM + +R++FK + +L +QLE L+QE +PDL+ HF
Sbjct: 583 AAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFL 642
Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
S +YA + I+D+ L EGI ++F VAL LL K+DLL
Sbjct: 643 DISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLT 702
Query: 406 DMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAV 463
D E LK+ + +LP + +++ A M LA ++K++ KK+KK EKEY ++ ++
Sbjct: 703 DFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDP 762
Query: 464 LRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFALDREVQALRRA 519
+ +ENR L++ V ++ D EE+ AL++E+ ++
Sbjct: 763 IERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQK 822
Query: 520 NVDMQQRLAVALDEIRSL-EMTIAENNSRQSSLEGTESASG 559
+D ++ +E L EM E + +S ++ S G
Sbjct: 823 LIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIG 863
Score = 35.1 bits (77), Expect = 1.1
Identities = 32/135 (23%), Positives = 68/135 (50%), Gaps = 9/135 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH-KYADLESKAK 775
K+MEL +++S +L++ ++E +RE Q+E ++ +RE + + A++ + +
Sbjct: 727 KLMELACNMKISQKKLKKYEKEYHTMREQ---QAQQEDPIERFERENRRLQEANMRLEQE 783
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
+ + + + A R E L E++ T+ +L +D + R L+E+ A+
Sbjct: 784 NDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKL----IDAEEEKRRLEEESAQ 839
Query: 836 LKAEIMRLEAWKSRA 850
LK E+ R E K+ +
Sbjct: 840 LK-EMCRRELDKAES 853
>AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating
protein, GAPCenA protein.
Length = 997
Score = 251 bits (615), Expect = 7e-66
Identities = 140/401 (34%), Positives = 215/401 (53%), Gaps = 8/401 (1%)
Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEK-KLYAS 225
E + WG L+S W R + + LVR GVP RG VWQLLAG + + Y
Sbjct: 463 EKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRI 522
Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
I +S + I RDI RT+P HD+FK+ G GQ+SL+ + KAYS++D E+GYCQG F+
Sbjct: 523 LITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFL 582
Query: 286 VGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
+LL+ MPEE+AF+VLVKIM + +R++FK + +L +QLE L+QE +PDL+ HF
Sbjct: 583 AAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFL 642
Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
S +YA + I+D+ L EGI ++F VAL LL K+DLL
Sbjct: 643 DISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLT 702
Query: 406 DMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAV 463
D E LK+ + +LP + +++ A M LA ++K++ KK+KK EKEY ++ ++
Sbjct: 703 DFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDP 762
Query: 464 LRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFALDREVQALRRA 519
+ +ENR L++ V ++ D EE+ AL++E+ ++
Sbjct: 763 IERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQK 822
Query: 520 NVDMQQRLAVALDEIRSL-EMTIAENNSRQSSLEGTESASG 559
+D ++ +E L EM E + +S ++ S G
Sbjct: 823 LIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIG 863
Score = 35.1 bits (77), Expect = 1.1
Identities = 32/135 (23%), Positives = 68/135 (50%), Gaps = 9/135 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH-KYADLESKAK 775
K+MEL +++S +L++ ++E +RE Q+E ++ +RE + + A++ + +
Sbjct: 727 KLMELACNMKISQKKLKKYEKEYHTMREQ---QAQQEDPIERFERENRRLQEANMRLEQE 783
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
+ + + + A R E L E++ T+ +L +D + R L+E+ A+
Sbjct: 784 NDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKL----IDAEEEKRRLEEESAQ 839
Query: 836 LKAEIMRLEAWKSRA 850
LK E+ R E K+ +
Sbjct: 840 LK-EMCRRELDKAES 853
>Z99127-7|CAI18937.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AY364260-1|AAQ76819.1| 468|Homo sapiens HHL protein.
Length = 468
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 160 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 218
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 219 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 278
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 279 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 338
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 339 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 398
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 399 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 453
>AL591108-1|CAH70225.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AL161671-6|CAI16281.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AL136377-4|CAI22935.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AL031286-3|CAI22382.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AL022400-4|CAI22878.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AL022171-4|CAI20384.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AK095838-1|BAC04635.1| 815|Homo sapiens protein ( Homo sapiens
cDNA FLJ38519 fis, clone HCHON2000751, moderately
similar to Rab6 GTPase activating protein. ).
Length = 815
Score = 244 bits (598), Expect = 8e-64
Identities = 126/295 (42%), Positives = 173/295 (58%), Gaps = 4/295 (1%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV-DTSPEKKLYA 224
E+ L+S WG L+ W S R + + LV+ GVP R VWQLLAG D Y
Sbjct: 507 EKILYS-WGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYR 565
Query: 225 SYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGF 284
I SA E VI RDI RT+P HD+FK+ G GQESL+ + KAYS++D ++GYCQG F
Sbjct: 566 ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
Query: 285 IVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHF 344
+ +LL+ MPEE+AF VLVKIM + +RD+++ + +L +QLE L+QE LPDLH HF
Sbjct: 626 LAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHF 685
Query: 345 QSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
+ +YA + I+D+ L EG+ I+F VALALL K DLL
Sbjct: 686 SDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQ 745
Query: 405 LDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTVIKTKE 457
D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY ++ +
Sbjct: 746 ADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQ 800
>AB209513-1|BAD92750.1| 307|Homo sapiens ecotropic viral
integration site 5 variant protein.
Length = 307
Score = 168 bits (409), Expect = 7e-41
Identities = 112/328 (34%), Positives = 167/328 (50%), Gaps = 36/328 (10%)
Query: 397 LGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTK 456
+ + +L+ LDME +L++ QK +P + + + AY VK N KKMKKLEKEYT IKTK
Sbjct: 1 MNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTK 60
Query: 457 EQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQAL 516
E + ++ LR ENRLLKQR+ ++GQV RA+ EE + + RE+ +
Sbjct: 61 EMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATI 120
Query: 517 RRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXX 576
++ + + +L A + IR L+ + +Q S +E+ L+
Sbjct: 121 KQQSDEASAKLEQAENTIRKLQ------HQQQ-----WHKCSSNYNEDFVLQLEKELVQA 169
Query: 577 XXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKD 636
+ ++E N SL + NN+A LQ+ELIAVKLREAEA + LK+
Sbjct: 170 RLSEAESQCALKEMQDKVLDIEKRNNSLPDE---NNIARLQEELIAVKLREAEAIMGLKE 226
Query: 637 LRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEE 696
LRQ+V +L E WQRHL + PKK M +L +E
Sbjct: 227 LRQQVKDLEEHWQRHL-------------ARTTGRWKDPPKK---------NAMNELQDE 264
Query: 697 LMTTRIREVEALTELKELRLKVMELETQ 724
LMT R+RE E E++E++ ++ME+ETQ
Sbjct: 265 LMTIRLREAETQAEIREIKQRMMEMETQ 292
Score = 44.4 bits (100), Expect = 0.002
Identities = 59/237 (24%), Positives = 109/237 (45%), Gaps = 25/237 (10%)
Query: 594 IDELENENKSLRR--QRVDNNVAHLQDELI---AVKLREAEANLSLKDLRQRVSELSESW 648
I L EN+ L++ + ++ A L D LI + +EAE N +K EL+
Sbjct: 68 IKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIK------RELAT-- 119
Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSAD-MLKLDEELMTTRIREVEA 707
+++ EA A Q+ + ++ + + D +L+L++EL+ R+ E E+
Sbjct: 120 ---IKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLSEAES 176
Query: 708 LTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKY 767
LKE++ KV+++E + N L ++ AR L+E L A RE +E + +
Sbjct: 177 QCALKEMQDKVLDIEKR----NNSLPDENNIAR-LQEELIAVKLREAEAIMGLKELRQQV 231
Query: 768 ADLESKAKYESMQANIRNMEDAQRIA--ELETEVSEYKLKN-EVMATEGELRNNNMD 821
DLE + + R + ++ A EL+ E+ +L+ E A E++ M+
Sbjct: 232 KDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMME 288
Score = 41.9 bits (94), Expect = 0.010
Identities = 41/193 (21%), Positives = 85/193 (44%), Gaps = 8/193 (4%)
Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW---EGRSADMLKLDEELMTTRIREV 705
Q L + E Q + P KL++A + S M KL++E T + +E+
Sbjct: 3 QAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEM 62
Query: 706 EALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
E E+K LR + L+ +++ T + RL++ + A + E ++
Sbjct: 63 EEQVEIKRLRTENRLLKQRIE--TLEKESASLADRLIQGQVTRAQEAEENYLIKRELATI 120
Query: 766 KYADLESKAKYESMQANIRNMEDAQRIAELETEVSE-YKLKNEVMATEGELRNNNMDDSD 824
K E+ AK E + IR ++ Q+ + + +E + L+ E + L + +
Sbjct: 121 KQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARL--SEAESQC 178
Query: 825 RVRELQEQVAELK 837
++E+Q++V +++
Sbjct: 179 ALKEMQDKVLDIE 191
Score = 40.7 bits (91), Expect = 0.022
Identities = 50/212 (23%), Positives = 91/212 (42%), Gaps = 31/212 (14%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQD---------ELIAVKLREAEANLSLKDLRQRVSEL 644
I+ LE E+ SL + + V Q+ EL +K + EA+ L+ + +L
Sbjct: 82 IETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEASAKLEQAENTIRKL 141
Query: 645 SESWQRH-----------LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSA----- 688
Q H LQ K+ A ++ + K+L + ++
Sbjct: 142 QHQQQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPDEN 201
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELET--QVQVSTNQLRRQDEEAR----LL 742
++ +L EEL+ ++RE EA+ LKELR +V +LE Q ++ R +D + L
Sbjct: 202 NIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNEL 261
Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKA 774
++ L RE Q RE + + ++E+++
Sbjct: 262 QDELMTIRLREAETQAEIREIKQRMMEMETQS 293
>BC126979-1|AAI26980.1| 432|Homo sapiens TBC1D1 protein protein.
Length = 432
Score = 165 bits (401), Expect = 6e-40
Identities = 113/394 (28%), Positives = 192/394 (48%), Gaps = 16/394 (4%)
Query: 167 EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------DT 216
+++ ++W +++S S+ K + + V QGVP H RG +W+ LA
Sbjct: 32 KEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQ 91
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P+ Y +K ++ + I D+ RT+P H +F + G GQ SL+N++KAYSL D+EV
Sbjct: 92 QPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEV 151
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EEEAF +L +M +R ++P M L + M+QL L+ +
Sbjct: 152 GYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 211
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + SLYA R+ D+ +G E++FKVAL+LL
Sbjct: 212 HRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLG 271
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
K +L + +E+I+ +I+ LP +N + + + K+++ E EY V++
Sbjct: 272 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ- 329
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
+E D + L ++ ++L K V G++ E E L E
Sbjct: 330 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-S 387
Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQ 548
L++A + ++ + L + L AE + R+
Sbjct: 388 KLKQAMLTLELERSALLQTVEELRRRSAEPSDRE 421
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/44 (38%), Positives = 29/44 (65%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
L++ +LR+ N+D+ ++L VA I+SLE TI + S +S L+
Sbjct: 347 LEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK 390
>BC053648-1|AAH53648.1| 891|Homo sapiens TBC1D1 protein protein.
Length = 891
Score = 165 bits (401), Expect = 6e-40
Identities = 113/394 (28%), Positives = 192/394 (48%), Gaps = 16/394 (4%)
Query: 167 EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------DT 216
+++ ++W +++S S+ K + + V QGVP H RG +W+ LA
Sbjct: 491 KEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQ 550
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P+ Y +K ++ + I D+ RT+P H +F + G GQ SL+N++KAYSL D+EV
Sbjct: 551 QPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEV 610
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EEEAF +L +M +R ++P M L + M+QL L+ +
Sbjct: 611 GYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 670
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + SLYA R+ D+ +G E++FKVAL+LL
Sbjct: 671 HRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLG 730
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
K +L + +E+I+ +I+ LP +N + + + K+++ E EY V++
Sbjct: 731 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ- 788
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
+E D + L ++ ++L K V G++ E E L E
Sbjct: 789 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-S 846
Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQ 548
L++A + ++ + L + L AE + R+
Sbjct: 847 KLKQAMLTLELERSALLQTVEELRRRSAEPSDRE 880
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/44 (38%), Positives = 29/44 (65%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
L++ +LR+ N+D+ ++L VA I+SLE TI + S +S L+
Sbjct: 806 LEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK 849
>BC050321-1|AAH50321.3| 1168|Homo sapiens TBC1 (tre-2/USP6, BUB2,
cdc16) domain family, member 1 protein.
Length = 1168
Score = 165 bits (401), Expect = 6e-40
Identities = 113/394 (28%), Positives = 192/394 (48%), Gaps = 16/394 (4%)
Query: 167 EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------DT 216
+++ ++W +++S S+ K + + V QGVP H RG +W+ LA
Sbjct: 768 KEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQ 827
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P+ Y +K ++ + I D+ RT+P H +F + G GQ SL+N++KAYSL D+EV
Sbjct: 828 QPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEV 887
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EEEAF +L +M +R ++P M L + M+QL L+ +
Sbjct: 888 GYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 947
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + SLYA R+ D+ +G E++FKVAL+LL
Sbjct: 948 HRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLG 1007
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
K +L + +E+I+ +I+ LP +N + + + K+++ E EY V++
Sbjct: 1008 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ- 1065
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
+E D + L ++ ++L K V G++ E E L E
Sbjct: 1066 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-S 1123
Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQ 548
L++A + ++ + L + L AE + R+
Sbjct: 1124 KLKQAMLTLELERSALLQTVEELRRRSAEPSDRE 1157
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/44 (38%), Positives = 29/44 (65%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
L++ +LR+ N+D+ ++L VA I+SLE TI + S +S L+
Sbjct: 1083 LEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK 1126
>BC014529-1|AAH14529.1| 900|Homo sapiens TBC1D1 protein protein.
Length = 900
Score = 165 bits (401), Expect = 6e-40
Identities = 113/394 (28%), Positives = 192/394 (48%), Gaps = 16/394 (4%)
Query: 167 EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------DT 216
+++ ++W +++S S+ K + + V QGVP H RG +W+ LA
Sbjct: 500 KEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQ 559
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P+ Y +K ++ + I D+ RT+P H +F + G GQ SL+N++KAYSL D+EV
Sbjct: 560 QPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEV 619
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EEEAF +L +M +R ++P M L + M+QL L+ +
Sbjct: 620 GYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 679
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + SLYA R+ D+ +G E++FKVAL+LL
Sbjct: 680 HRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLG 739
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
K +L + +E+I+ +I+ LP +N + + + K+++ E EY V++
Sbjct: 740 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ- 797
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
+E D + L ++ ++L K V G++ E E L E
Sbjct: 798 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-S 855
Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQ 548
L++A + ++ + L + L AE + R+
Sbjct: 856 KLKQAMLTLELERSALLQTVEELRRRSAEPSDRE 889
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/44 (38%), Positives = 29/44 (65%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
L++ +LR+ N+D+ ++L VA I+SLE TI + S +S L+
Sbjct: 815 LEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK 858
>AK027355-1|BAB55057.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ14449 fis, clone HEMBB1001684. ).
Length = 674
Score = 165 bits (401), Expect = 6e-40
Identities = 113/394 (28%), Positives = 192/394 (48%), Gaps = 16/394 (4%)
Query: 167 EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------DT 216
+++ ++W +++S S+ K + + V QGVP H RG +W+ LA
Sbjct: 274 KEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQ 333
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P+ Y +K ++ + I D+ RT+P H +F + G GQ SL+N++KAYSL D+EV
Sbjct: 334 QPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEV 393
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EEEAF +L +M +R ++P M L + M+QL L+ +
Sbjct: 394 GYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 453
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + SLYA R+ D+ +G E++FKVAL+LL
Sbjct: 454 HRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLG 513
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
K +L + +E+I+ +I+ LP +N + + + K+++ E EY V++
Sbjct: 514 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ- 571
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
+E D + L ++ ++L K V G++ E E L E
Sbjct: 572 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-S 629
Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQ 548
L++A + ++ + L + L AE + R+
Sbjct: 630 KLKQAMLTLELERSALLQTVEELRRRSAEPSDRE 663
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/44 (38%), Positives = 29/44 (65%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
L++ +LR+ N+D+ ++L VA I+SLE TI + S +S L+
Sbjct: 589 LEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK 632
>AB029031-1|BAA83060.1| 763|Homo sapiens KIAA1108 protein protein.
Length = 763
Score = 165 bits (401), Expect = 6e-40
Identities = 113/394 (28%), Positives = 192/394 (48%), Gaps = 16/394 (4%)
Query: 167 EDLWSLWGRLVSN-WESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGV---------DT 216
+++ ++W +++S S+ K + + V QGVP H RG +W+ LA
Sbjct: 363 KEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQ 422
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P+ Y +K ++ + I D+ RT+P H +F + G GQ SL+N++KAYSL D+EV
Sbjct: 423 QPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEV 482
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EEEAF +L +M +R ++P M L + M+QL L+ +
Sbjct: 483 GYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDY 542
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + SLYA R+ D+ +G E++FKVAL+LL
Sbjct: 543 HRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLG 602
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
K +L + +E+I+ +I+ LP +N + + + K+++ E EY V++
Sbjct: 603 SHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ- 660
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQ 514
+E D + L ++ ++L K V G++ E E L E
Sbjct: 661 EELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-S 718
Query: 515 ALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQ 548
L++A + ++ + L + L AE + R+
Sbjct: 719 KLKQAMLTLELERSALLQTVEELRRRSAEPSDRE 752
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/44 (38%), Positives = 29/44 (65%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
L++ +LR+ N+D+ ++L VA I+SLE TI + S +S L+
Sbjct: 678 LEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK 721
>AL162571-2|CAI39591.1| 1298|Homo sapiens TBC1 domain family, member 4
protein.
Length = 1298
Score = 163 bits (397), Expect = 2e-39
Identities = 91/303 (30%), Positives = 159/303 (52%), Gaps = 11/303 (3%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA---------GVDT 216
++++ W + + N ++ + + + L+++GVP RG +WQ LA
Sbjct: 886 QKEVLITWDKKLLNCRAKIRCDMEDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNKQ 945
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P Y +K +A + I D+ RT+P H +F + G GQ SLFN++KAYSL D+EV
Sbjct: 946 QPPDISYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEV 1005
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EE+AF +L +M R ++P M L + M+QL L+ +
Sbjct: 1006 GYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDY 1065
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + S SLYA R+ D+ +G E++FKVAL+LL+
Sbjct: 1066 HRDLYNHLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLS 1125
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
+ ++ + E+I+++++ LP ++ + + + ++ K++ E EY V++
Sbjct: 1126 SQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDIS-KQLHAYEVEYHVLQD 1184
Query: 456 KEQ 458
+ Q
Sbjct: 1185 ELQ 1187
>AL139230-1|CAH70991.1| 1298|Homo sapiens TBC1 domain family, member 4
protein.
Length = 1298
Score = 163 bits (397), Expect = 2e-39
Identities = 91/303 (30%), Positives = 159/303 (52%), Gaps = 11/303 (3%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA---------GVDT 216
++++ W + + N ++ + + + L+++GVP RG +WQ LA
Sbjct: 886 QKEVLITWDKKLLNCRAKIRCDMEDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNKQ 945
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P Y +K +A + I D+ RT+P H +F + G GQ SLFN++KAYSL D+EV
Sbjct: 946 QPPDISYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEV 1005
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EE+AF +L +M R ++P M L + M+QL L+ +
Sbjct: 1006 GYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDY 1065
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + S SLYA R+ D+ +G E++FKVAL+LL+
Sbjct: 1066 HRDLYNHLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLS 1125
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
+ ++ + E+I+++++ LP ++ + + + ++ K++ E EY V++
Sbjct: 1126 SQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDIS-KQLHAYEVEYHVLQD 1184
Query: 456 KEQ 458
+ Q
Sbjct: 1185 ELQ 1187
>AB011175-1|BAA25529.2| 1348|Homo sapiens KIAA0603 protein protein.
Length = 1348
Score = 163 bits (397), Expect = 2e-39
Identities = 91/303 (30%), Positives = 159/303 (52%), Gaps = 11/303 (3%)
Query: 166 EEDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLA---------GVDT 216
++++ W + + N ++ + + + L+++GVP RG +WQ LA
Sbjct: 936 QKEVLITWDKKLLNCRAKIRCDMEDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNKQ 995
Query: 217 SPEKKLYASYIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREV 276
P Y +K +A + I D+ RT+P H +F + G GQ SLFN++KAYSL D+EV
Sbjct: 996 QPPDISYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEV 1055
Query: 277 GYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQEL 336
GYCQG F+ G+LL+ M EE+AF +L +M R ++P M L + M+QL L+ +
Sbjct: 1056 GYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDY 1115
Query: 337 LPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLT 396
DL+ H + S SLYA R+ D+ +G E++FKVAL+LL+
Sbjct: 1116 HRDLYNHLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLS 1175
Query: 397 LGKNDLLSLD-MESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKT 455
+ ++ + E+I+++++ LP ++ + + + ++ K++ E EY V++
Sbjct: 1176 SQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDIS-KQLHAYEVEYHVLQD 1234
Query: 456 KEQ 458
+ Q
Sbjct: 1235 ELQ 1237
>D13644-1|BAA02807.2| 838|Homo sapiens KIAA0019 protein protein.
Length = 838
Score = 136 bits (330), Expect = 2e-31
Identities = 81/253 (32%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE--KKLYASYIKAK 230
W +++ WE ++K ++ R + + G+P RG VW LL + E + LY+
Sbjct: 87 WLKMLKGWE-KYKNTEKFHRRIYK-GIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRA 144
Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
C IR+ D+ RT+ +H F+++ G+ Q+SLF+V+ AYS+++ EVGYCQG I
Sbjct: 145 RGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITA 204
Query: 288 LLLMQMPEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
LLLM M EE+AF LVK+ +H M F +L E ++ + L L H
Sbjct: 205 LLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD 264
Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
SQ TS Y L RI D+++ EG ++ ++ +L L K L+ L
Sbjct: 265 SQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKL 324
Query: 406 DMESILKYIQKEL 418
ME ++++ Q+ L
Sbjct: 325 SMEELVEFFQETL 337
>BC042943-1|AAH42943.1| 828|Homo sapiens USP6 N-terminal like
protein.
Length = 828
Score = 136 bits (330), Expect = 2e-31
Identities = 81/253 (32%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE--KKLYASYIKAK 230
W +++ WE ++K ++ R + + G+P RG VW LL + E + LY+
Sbjct: 77 WLKMLKGWE-KYKNTEKFHRRIYK-GIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRA 134
Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
C IR+ D+ RT+ +H F+++ G+ Q+SLF+V+ AYS+++ EVGYCQG I
Sbjct: 135 RGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITA 194
Query: 288 LLLMQMPEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
LLLM M EE+AF LVK+ +H M F +L E ++ + L L H
Sbjct: 195 LLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD 254
Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
SQ TS Y L RI D+++ EG ++ ++ +L L K L+ L
Sbjct: 255 SQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKL 314
Query: 406 DMESILKYIQKEL 418
ME ++++ Q+ L
Sbjct: 315 SMEELVEFFQETL 327
>AL590416-1|CAI16966.1| 828|Homo sapiens USP6 N-terminal like
protein.
Length = 828
Score = 136 bits (330), Expect = 2e-31
Identities = 81/253 (32%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE--KKLYASYIKAK 230
W +++ WE ++K ++ R + + G+P RG VW LL + E + LY+
Sbjct: 77 WLKMLKGWE-KYKNTEKFHRRIYK-GIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRA 134
Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
C IR+ D+ RT+ +H F+++ G+ Q+SLF+V+ AYS+++ EVGYCQG I
Sbjct: 135 RGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITA 194
Query: 288 LLLMQMPEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
LLLM M EE+AF LVK+ +H M F +L E ++ + L L H
Sbjct: 195 LLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD 254
Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
SQ TS Y L RI D+++ EG ++ ++ +L L K L+ L
Sbjct: 255 SQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKL 314
Query: 406 DMESILKYIQKEL 418
ME ++++ Q+ L
Sbjct: 315 SMEELVEFFQETL 327
>AL512631-1|CAH70484.1| 828|Homo sapiens USP6 N-terminal like
protein.
Length = 828
Score = 136 bits (330), Expect = 2e-31
Identities = 81/253 (32%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE--KKLYASYIKAK 230
W +++ WE ++K ++ R + + G+P RG VW LL + E + LY+
Sbjct: 77 WLKMLKGWE-KYKNTEKFHRRIYK-GIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRA 134
Query: 231 SACEKVIRR---DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
C IR+ D+ RT+ +H F+++ G+ Q+SLF+V+ AYS+++ EVGYCQG I
Sbjct: 135 RGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITA 194
Query: 288 LLLMQMPEEEAFAVLVKIMQ--QHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQ 345
LLLM M EE+AF LVK+ +H M F +L E ++ + L L H
Sbjct: 195 LLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD 254
Query: 346 SQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
SQ TS Y L RI D+++ EG ++ ++ +L L K L+ L
Sbjct: 255 SQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKL 314
Query: 406 DMESILKYIQKEL 418
ME ++++ Q+ L
Sbjct: 315 SMEELVEFFQETL 327
>BC062999-1|AAH62999.1| 446|Homo sapiens TBC1 domain family, member
10C protein.
Length = 446
Score = 130 bits (313), Expect = 3e-29
Identities = 85/281 (30%), Positives = 134/281 (47%), Gaps = 11/281 (3%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAK 230
W + S+WE RR + V+ R+G+P R W LL G + Y +A
Sbjct: 67 WVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAEAP 126
Query: 231 SACE--KVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
+ + I RD+ R +P H+ F G GQ+ L V+KAY+L+ E GYCQ G + +
Sbjct: 127 GDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAV 186
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
LLM +P EEAF LV+I + + + + P M + L L++ LLP +H H Q
Sbjct: 187 LLMHLPPEEAFWCLVQICEVY-LPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVG 245
Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL--LTLGKNDLLSLD 406
LY P R+ D FLSEG ++F+V L L L LG +
Sbjct: 246 VGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAEQRGA- 304
Query: 407 MESILKYI--QKELPLKAEADQAAFMNLAYSVKVNPKKMKK 445
+L+ + + +P A+ + AFM+ +SV ++ + +++
Sbjct: 305 CPGLLETLGALRAIP-PAQLQEEAFMSQVHSVVLSERDLQR 344
>BC036873-1|AAH36873.3| 446|Homo sapiens TBC1 domain family, member
10C protein.
Length = 446
Score = 130 bits (313), Expect = 3e-29
Identities = 85/281 (30%), Positives = 134/281 (47%), Gaps = 11/281 (3%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAK 230
W + S+WE RR + V+ R+G+P R W LL G + Y +A
Sbjct: 67 WVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAEAP 126
Query: 231 SACE--KVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
+ + I RD+ R +P H+ F G GQ+ L V+KAY+L+ E GYCQ G + +
Sbjct: 127 GDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAV 186
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQS 348
LLM +P EEAF LV+I + + + + P M + L L++ LLP +H H Q
Sbjct: 187 LLMHLPPEEAFWCLVQICEVY-LPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVG 245
Query: 349 FSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL--LTLGKNDLLSLD 406
LY P R+ D FLSEG ++F+V L L L LG +
Sbjct: 246 VGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAEQRGA- 304
Query: 407 MESILKYI--QKELPLKAEADQAAFMNLAYSVKVNPKKMKK 445
+L+ + + +P A+ + AFM+ +SV ++ + +++
Sbjct: 305 CPGLLETLGALRAIP-PAQLQEEAFMSQVHSVVLSERDLQR 344
>CT841514-1|CAJ86444.1| 508|Homo sapiens dJ130H16.2 protein.
Length = 508
Score = 128 bits (308), Expect = 1e-28
Identities = 86/302 (28%), Positives = 144/302 (47%), Gaps = 10/302 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASY 226
S W +++NW+ ++++ +R ++G+P RG WQ L+G + +P K
Sbjct: 84 SKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDM 143
Query: 227 IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
VI RD+ R +P H+ F + G GQ+ LF V+KAY+L+ E GYCQ I
Sbjct: 144 SPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIA 203
Query: 287 GLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
+LLM MP E+AF LV+I +++ + + + + L L +L+Q++ P H H
Sbjct: 204 AVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR 262
Query: 347 QSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLLS 404
Q LY R+ D+F EG++I+F+V L LL LG + +
Sbjct: 263 QKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVK 322
Query: 405 LDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVL 464
+ + I++ L + Q AF L V P +++E+E+ + + Q L
Sbjct: 323 A-CQGQYETIERLRSLSPKIMQEAF--LVQEVVELPVTERQIEREHLIQLRRWQETRGEL 379
Query: 465 RC 466
+C
Sbjct: 380 QC 381
>AK074656-1|BAC11117.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ90175 fis, clone MAMMA1000496, weakly similar to
MIC1 PROTEIN. ).
Length = 508
Score = 128 bits (308), Expect = 1e-28
Identities = 86/302 (28%), Positives = 144/302 (47%), Gaps = 10/302 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASY 226
S W +++NW+ ++++ +R ++G+P RG WQ L+G + +P K
Sbjct: 84 SKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDM 143
Query: 227 IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
VI RD+ R +P H+ F + G GQ+ LF V+KAY+L+ E GYCQ I
Sbjct: 144 SPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIA 203
Query: 287 GLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
+LLM MP E+AF LV+I +++ + + + + L L +L+Q++ P H H
Sbjct: 204 AVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR 262
Query: 347 QSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLLS 404
Q LY R+ D+F EG++I+F+V L LL LG + +
Sbjct: 263 QKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVK 322
Query: 405 LDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVL 464
+ + I++ L + Q AF L V P +++E+E+ + + Q L
Sbjct: 323 A-CQGQYETIERLRSLSPKIMQEAF--LVQEVVELPVTERQIEREHLIQLRRWQETRGEL 379
Query: 465 RC 466
+C
Sbjct: 380 QC 381
>AF331038-1|AAK35048.1| 508|Homo sapiens EPI64 protein.
Length = 508
Score = 128 bits (308), Expect = 1e-28
Identities = 86/302 (28%), Positives = 144/302 (47%), Gaps = 10/302 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASY 226
S W +++NW+ ++++ +R ++G+P RG WQ L+G + +P K
Sbjct: 84 SKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDM 143
Query: 227 IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
VI RD+ R +P H+ F + G GQ+ LF V+KAY+L+ E GYCQ I
Sbjct: 144 SPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIA 203
Query: 287 GLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
+LLM MP E+AF LV+I +++ + + + + L L +L+Q++ P H H
Sbjct: 204 AVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR 262
Query: 347 QSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLLS 404
Q LY R+ D+F EG++I+F+V L LL LG + +
Sbjct: 263 QKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVK 322
Query: 405 LDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVL 464
+ + I++ L + Q AF L V P +++E+E+ + + Q L
Sbjct: 323 A-CQGQYETIERLRSLSPKIMQEAF--LVQEVVELPVTERQIEREHLIQLRRWQETRGEL 379
Query: 465 RC 466
+C
Sbjct: 380 QC 381
>AC004997-3|AAC23434.1| 438|Homo sapiens WUGSC:H_DJ130H16.2
protein.
Length = 438
Score = 128 bits (308), Expect = 1e-28
Identities = 86/302 (28%), Positives = 144/302 (47%), Gaps = 10/302 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASY 226
S W +++NW+ ++++ +R ++G+P RG WQ L+G + +P K
Sbjct: 14 SKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDM 73
Query: 227 IKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIV 286
VI RD+ R +P H+ F + G GQ+ LF V+KAY+L+ E GYCQ I
Sbjct: 74 SPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIA 133
Query: 287 GLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQS 346
+LLM MP E+AF LV+I +++ + + + + L L +L+Q++ P H H
Sbjct: 134 AVLLMHMPAEQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR 192
Query: 347 QSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKNDLLS 404
Q LY R+ D+F EG++I+F+V L LL LG + +
Sbjct: 193 QKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVK 252
Query: 405 LDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVL 464
+ + I++ L + Q AF L V P +++E+E+ + + Q L
Sbjct: 253 A-CQGQYETIERLRSLSPKIMQEAF--LVQEVVELPVTERQIEREHLIQLRRWQETRGEL 309
Query: 465 RC 466
+C
Sbjct: 310 QC 311
>BC098419-1|AAH98419.1| 668|Homo sapiens TBC1D10B protein protein.
Length = 668
Score = 116 bits (278), Expect = 5e-25
Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
W + SNW+ RR Q V+ R+G+P R WQ L+ ++ +P K
Sbjct: 195 WLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP 254
Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
VI +D+ R +P H+ F + G GQ+ L+ ++KAY+++ + GYCQ + +
Sbjct: 255 GDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAV 314
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN-----LVQELLPDLHVH 343
LLM MP E+AF LV+I D + P GL QL+ L++ P H H
Sbjct: 315 LLMHMPAEQAFWCLVQIC------DKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRH 368
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
+ Q LY R+ D+F EG++I+F+VAL LL TLG +
Sbjct: 369 LRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVE 428
Query: 402 LL 403
L
Sbjct: 429 KL 430
>BC093816-1|AAH93816.1| 533|Homo sapiens TBC1 domain family, member
10B protein.
Length = 533
Score = 116 bits (278), Expect = 5e-25
Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
W + SNW+ RR Q V+ R+G+P R WQ L+ ++ +P K
Sbjct: 60 WLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP 119
Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
VI +D+ R +P H+ F + G GQ+ L+ ++KAY+++ + GYCQ + +
Sbjct: 120 GDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAV 179
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN-----LVQELLPDLHVH 343
LLM MP E+AF LV+I D + P GL QL+ L++ P H H
Sbjct: 180 LLMHMPAEQAFWCLVQIC------DKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRH 233
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
+ Q LY R+ D+F EG++I+F+VAL LL TLG +
Sbjct: 234 LRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVE 293
Query: 402 LL 403
L
Sbjct: 294 KL 295
>BC093814-1|AAH93814.1| 533|Homo sapiens TBC1 domain family, member
10B protein.
Length = 533
Score = 116 bits (278), Expect = 5e-25
Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
W + SNW+ RR Q V+ R+G+P R WQ L+ ++ +P K
Sbjct: 60 WLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP 119
Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
VI +D+ R +P H+ F + G GQ+ L+ ++KAY+++ + GYCQ + +
Sbjct: 120 GDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAV 179
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN-----LVQELLPDLHVH 343
LLM MP E+AF LV+I D + P GL QL+ L++ P H H
Sbjct: 180 LLMHMPAEQAFWCLVQIC------DKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRH 233
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
+ Q LY R+ D+F EG++I+F+VAL LL TLG +
Sbjct: 234 LRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVE 293
Query: 402 LL 403
L
Sbjct: 294 KL 295
>BC072453-1|AAH72453.2| 533|Homo sapiens TBC1 domain family, member
10B protein.
Length = 533
Score = 116 bits (278), Expect = 5e-25
Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
W + SNW+ RR Q V+ R+G+P R WQ L+ ++ +P K
Sbjct: 60 WLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP 119
Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
VI +D+ R +P H+ F + G GQ+ L+ ++KAY+++ + GYCQ + +
Sbjct: 120 GDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAV 179
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN-----LVQELLPDLHVH 343
LLM MP E+AF LV+I D + P GL QL+ L++ P H H
Sbjct: 180 LLMHMPAEQAFWCLVQIC------DKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRH 233
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
+ Q LY R+ D+F EG++I+F+VAL LL TLG +
Sbjct: 234 LRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVE 293
Query: 402 LL 403
L
Sbjct: 294 KL 295
>BC063112-1|AAH63112.1| 622|Homo sapiens TBC1D10B protein protein.
Length = 622
Score = 116 bits (278), Expect = 5e-25
Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
W + SNW+ RR Q V+ R+G+P R WQ L+ ++ +P K
Sbjct: 149 WLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP 208
Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
VI +D+ R +P H+ F + G GQ+ L+ ++KAY+++ + GYCQ + +
Sbjct: 209 GDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAV 268
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN-----LVQELLPDLHVH 343
LLM MP E+AF LV+I D + P GL QL+ L++ P H H
Sbjct: 269 LLMHMPAEQAFWCLVQIC------DKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRH 322
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
+ Q LY R+ D+F EG++I+F+VAL LL TLG +
Sbjct: 323 LRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVE 382
Query: 402 LL 403
L
Sbjct: 383 KL 384
>AK023192-1|BAB14454.1| 533|Homo sapiens protein ( Homo sapiens
cDNA FLJ13130 fis, clone NT2RP3002972, weakly similar to
Halocynthia roretzi mRNA for HrPET-1. ).
Length = 533
Score = 116 bits (278), Expect = 5e-25
Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG----VDTSPEKKLYASYIK 228
W + SNW+ RR Q V+ R+G+P R WQ L+ ++ +P K
Sbjct: 60 WLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAP 119
Query: 229 AKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGL 288
VI +D+ R +P H+ F + G GQ+ L+ ++KAY+++ + GYCQ + +
Sbjct: 120 GDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAV 179
Query: 289 LLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLEN-----LVQELLPDLHVH 343
LLM MP E+AF LV+I D + P GL QL+ L++ P H H
Sbjct: 180 LLMHMPAEQAFWCLVQIC------DKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRH 233
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL--TLGKND 401
+ Q LY R+ D+F EG++I+F+VAL LL TLG +
Sbjct: 234 LRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVE 293
Query: 402 LL 403
L
Sbjct: 294 KL 295
>BC033712-1|AAH33712.1| 415|Homo sapiens TBC1D2B protein protein.
Length = 415
Score = 105 bits (251), Expect = 9e-22
Identities = 71/290 (24%), Positives = 134/290 (46%), Gaps = 13/290 (4%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK---------LYASYIKAKSACEKVIRRDI 241
+++L+R G+PH R VW+ T K L ++ ++ K I D+
Sbjct: 107 LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDL 166
Query: 242 ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
RT P + + G + L NV+ A+S + ++GYCQG +V + L+ + +E+AF
Sbjct: 167 LRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWC 226
Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
LV I++ RD + ++ + +L+ E LP LH HF+ +L
Sbjct: 227 LVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLV 286
Query: 362 XXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQKELPL 420
+ +I D FL EG +++F+ ALAL + ++L L D SI KY++
Sbjct: 287 VFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLR--YFT 344
Query: 421 KAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
+ D +++++ +NP ++++ K + ++ L +R++
Sbjct: 345 RTILDARKLISISFG-DLNPFPLRQIRNRRAYHLEKVRLELTELEAIRED 393
>AB028978-1|BAA83007.1| 868|Homo sapiens KIAA1055 protein protein.
Length = 868
Score = 103 bits (248), Expect = 2e-21
Identities = 65/235 (27%), Positives = 111/235 (47%), Gaps = 10/235 (4%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK---------LYASYIKAKSACEKVIRRDI 241
+++L+R G+PH R VW+ T K L ++ ++ K I D+
Sbjct: 609 LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDL 668
Query: 242 ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
RT P + + G + L NV+ A+S + ++GYCQG +V + L+ + +E+AF
Sbjct: 669 LRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWC 728
Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
LV I++ RD + ++ + +L+ E LP LH HF+ +L
Sbjct: 729 LVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLV 788
Query: 362 XXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL-DMESILKYIQ 415
+ +I D FL EG +++F+ ALAL + ++L L D SI KY++
Sbjct: 789 VFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLR 843
>AL355341-2|CAH70583.2| 775|Homo sapiens TBC1 domain family, member
12 protein.
Length = 775
Score = 103 bits (246), Expect = 4e-21
Identities = 83/314 (26%), Positives = 148/314 (47%), Gaps = 31/314 (9%)
Query: 172 LW-GRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPE--------- 219
+W ++ NWE R + VR+L QG+P RG VW L G ++ +PE
Sbjct: 459 IWINEILPNWEV--MRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRA 516
Query: 220 KKLYASYIKAKS-------------ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVM 266
K+ + S+ + S A ++I+ DI+RT+P F +K G + L +++
Sbjct: 517 KERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIF-QKGGPYHDVLHSIL 575
Query: 267 KAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCM 326
AY+ + +VGY QG FI +L++ + E +AF ++ + F+ + +
Sbjct: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYF 635
Query: 327 FQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEI 386
E +E L L +HF+S S + +Y LACR+ DVF +G E
Sbjct: 636 ATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEF 695
Query: 387 VFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
+F+ L +L L ++ LL +D I +++ K LP +++ A ++ + KK ++
Sbjct: 696 LFRTGLGILRLYEDILLQMDFIHIAQFLTK-LPEDITSEKLFSCIAAIQMQNSTKKWTQV 754
Query: 447 EKEYTVIKTKEQGD 460
+V+K ++GD
Sbjct: 755 FA--SVMKDIKEGD 766
>AL138759-3|CAH70223.2| 775|Homo sapiens TBC1 domain family, member
12 protein.
Length = 775
Score = 103 bits (246), Expect = 4e-21
Identities = 83/314 (26%), Positives = 148/314 (47%), Gaps = 31/314 (9%)
Query: 172 LW-GRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPE--------- 219
+W ++ NWE R + VR+L QG+P RG VW L G ++ +PE
Sbjct: 459 IWINEILPNWEV--MRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRA 516
Query: 220 KKLYASYIKAKS-------------ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVM 266
K+ + S+ + S A ++I+ DI+RT+P F +K G + L +++
Sbjct: 517 KERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIF-QKGGPYHDVLHSIL 575
Query: 267 KAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCM 326
AY+ + +VGY QG FI +L++ + E +AF ++ + F+ + +
Sbjct: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYF 635
Query: 327 FQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEI 386
E +E L L +HF+S S + +Y LACR+ DVF +G E
Sbjct: 636 ATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEF 695
Query: 387 VFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
+F+ L +L L ++ LL +D I +++ K LP +++ A ++ + KK ++
Sbjct: 696 LFRTGLGILRLYEDILLQMDFIHIAQFLTK-LPEDITSEKLFSCIAAIQMQNSTKKWTQV 754
Query: 447 EKEYTVIKTKEQGD 460
+V+K ++GD
Sbjct: 755 FA--SVMKDIKEGD 766
>AB011180-1|BAA25534.1| 775|Homo sapiens KIAA0608 protein protein.
Length = 775
Score = 103 bits (246), Expect = 4e-21
Identities = 83/314 (26%), Positives = 148/314 (47%), Gaps = 31/314 (9%)
Query: 172 LW-GRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAG--VDTSPE--------- 219
+W ++ NWE R + VR+L QG+P RG VW L G ++ +PE
Sbjct: 459 IWINEILPNWEV--MRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRA 516
Query: 220 KKLYASYIKAKS-------------ACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVM 266
K+ + S+ + S A ++I+ DI+RT+P F +K G + L +++
Sbjct: 517 KERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIF-QKGGPYHDVLHSIL 575
Query: 267 KAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCM 326
AY+ + +VGY QG FI +L++ + E +AF ++ + F+ + +
Sbjct: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYF 635
Query: 327 FQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEI 386
E +E L L +HF+S S + +Y LACR+ DVF +G E
Sbjct: 636 ATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEF 695
Query: 387 VFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKL 446
+F+ L +L L ++ LL +D I +++ K LP +++ A ++ + KK ++
Sbjct: 696 LFRTGLGILRLYEDILLQMDFIHIAQFLTK-LPEDITSEKLFSCIAAIQMQNSTKKWTQV 754
Query: 447 EKEYTVIKTKEQGD 460
+V+K ++GD
Sbjct: 755 FA--SVMKDIKEGD 766
>CR456441-1|CAG30327.1| 749|Homo sapiens dJ1042K10.2 protein.
Length = 749
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
R++ +R LV G+PH R +W L+G + +L Y +K S E K I +D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ RT P + F +G L V++A + E+GYCQG+G + LL+ + EE+AF
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
++ I++ F ++ + L +L+ + LP L Q SL
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
L RI D+F EG ++F++ L +L L + +L+ + + + ++P
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 342
Query: 421 KAE 423
+ E
Sbjct: 343 QME 345
>BC041167-1|AAH41167.1| 678|Homo sapiens TBC1 domain family, member
14 protein.
Length = 678
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/273 (26%), Positives = 122/273 (44%), Gaps = 32/273 (11%)
Query: 176 LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLY------------ 223
++ NWE+ W R VRDL QG+P RG VW L G + + +L+
Sbjct: 366 ILPNWETMWCSRK--VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWR 423
Query: 224 -------------ASYIKA-KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAY 269
A + A + A ++I+ DI+RT+P F++ G + L +++ AY
Sbjct: 424 SLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ-GGPYHDMLHSILGAY 482
Query: 270 SLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQL 329
+ + +VGY QG FI +L++ + +AF ++ + F+ +
Sbjct: 483 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAF 542
Query: 330 ENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFK 389
E +E LP L HF+ + + +Y LACRI DVF +G E +F+
Sbjct: 543 EVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFR 602
Query: 390 VALALLTLGKNDLLSLD---MESILKYIQKELP 419
AL +L L ++ L +D M L + ++LP
Sbjct: 603 TALGILKLFEDILTKMDFIHMAQFLTRLPEDLP 635
>BC008078-1|AAH08078.1| 749|Homo sapiens RUN and TBC1 domain
containing 3 protein.
Length = 749
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
R++ +R LV G+PH R +W L+G + +L Y +K S E K I +D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ RT P + F +G L V++A + E+GYCQG+G + LL+ + EE+AF
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
++ I++ F ++ + L +L+ + LP L Q SL
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
L RI D+F EG ++F++ L +L L + +L+ + + + ++P
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 342
Query: 421 KAE 423
+ E
Sbjct: 343 QME 345
>AY308849-1|AAQ81879.1| 749|Homo sapiens merlin binding protein
protein.
Length = 749
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
R++ +R LV G+PH R +W L+G + +L Y +K S E K I +D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ RT P + F +G L V++A + E+GYCQG+G + LL+ + EE+AF
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
++ I++ F ++ + L +L+ + LP L Q SL
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
L RI D+F EG ++F++ L +L L + +L+ + + + ++P
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 342
Query: 421 KAE 423
+ E
Sbjct: 343 QME 345
>AL833868-1|CAD38726.1| 381|Homo sapiens hypothetical protein
protein.
Length = 381
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/273 (26%), Positives = 122/273 (44%), Gaps = 32/273 (11%)
Query: 176 LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLY------------ 223
++ NWE+ W R VRDL QG+P RG VW L G + + +L+
Sbjct: 69 ILPNWETMWCSRK--VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWR 126
Query: 224 -------------ASYIKA-KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAY 269
A + A + A ++I+ DI+RT+P F++ G + L +++ AY
Sbjct: 127 SLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ-GGPYHDMLHSILGAY 185
Query: 270 SLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQL 329
+ + +VGY QG FI +L++ + +AF ++ + F+ +
Sbjct: 186 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAF 245
Query: 330 ENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFK 389
E +E LP L HF+ + + +Y LACRI DVF +G E +F+
Sbjct: 246 EVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFR 305
Query: 390 VALALLTLGKNDLLSLD---MESILKYIQKELP 419
AL +L L ++ L +D M L + ++LP
Sbjct: 306 TALGILKLFEDILTKMDFIHMAQFLTRLPEDLP 338
>AL022238-3|CAA18266.1| 777|Homo sapiens protein ( Human DNA
sequence from clone RP5-1042K10 on chromosome
22q13.1-13.2. ).
Length = 777
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
R++ +R LV G+PH R +W L+G + +L Y +K S E K I +D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ RT P + F +G L V++A + E+GYCQG+G + LL+ + EE+AF
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
++ I++ F ++ + L +L+ + LP L Q SL
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
L RI D+F EG ++F++ L +L L + +L+ + + + ++P
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 342
Query: 421 KAE 423
+ E
Sbjct: 343 QME 345
>AK000006-1|BAA92231.1| 401|Homo sapiens FLJ00006 protein protein.
Length = 401
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
R++ +R LV G+PH R +W L+G + +L Y +K S E K I +D
Sbjct: 47 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 106
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ RT P + F +G L V++A + E+GYCQG+G + LL+ + EE+AF
Sbjct: 107 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 166
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
++ I++ F ++ + L +L+ + LP L Q SL
Sbjct: 167 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 226
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
L RI D+F EG ++F++ L +L L + +L+ + + + ++P
Sbjct: 227 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 286
Query: 421 KAE 423
+ E
Sbjct: 287 QME 289
>AB196956-1|BAE02561.1| 749|Homo sapiens
Rab-GTPase-activating-protein-like protein protein.
Length = 749
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 6/243 (2%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAG-VDTSPEKKL-YASYIKAKSACE----KVIRRD 240
R++ +R LV G+PH R +W L+G + +L Y +K S E K I +D
Sbjct: 103 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 162
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ RT P + F +G L V++A + E+GYCQG+G + LL+ + EE+AF
Sbjct: 163 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 222
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
++ I++ F ++ + L +L+ + LP L Q SL
Sbjct: 223 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 282
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPL 420
L RI D+F EG ++F++ L +L L + +L+ + + + ++P
Sbjct: 283 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 342
Query: 421 KAE 423
+ E
Sbjct: 343 QME 345
>AB037743-1|BAA92560.1| 702|Homo sapiens KIAA1322 protein protein.
Length = 702
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/273 (26%), Positives = 122/273 (44%), Gaps = 32/273 (11%)
Query: 176 LVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLY------------ 223
++ NWE+ W R VRDL QG+P RG VW L G + + +L+
Sbjct: 390 ILPNWETMWCSRK--VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWR 447
Query: 224 -------------ASYIKA-KSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAY 269
A + A + A ++I+ DI+RT+P F++ G + L +++ AY
Sbjct: 448 SLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ-GGPYHDMLHSILGAY 506
Query: 270 SLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQL 329
+ + +VGY QG FI +L++ + +AF ++ + F+ +
Sbjct: 507 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAF 566
Query: 330 ENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFK 389
E +E LP L HF+ + + +Y LACRI DVF +G E +F+
Sbjct: 567 EVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFR 626
Query: 390 VALALLTLGKNDLLSLD---MESILKYIQKELP 419
AL +L L ++ L +D M L + ++LP
Sbjct: 627 TALGILKLFEDILTKMDFIHMAQFLTRLPEDLP 659
>BC080640-1|AAH80640.1| 354|Homo sapiens Unknown (protein for
IMAGE:6644085) protein.
Length = 354
Score = 95.5 bits (227), Expect = 7e-19
Identities = 67/215 (31%), Positives = 106/215 (49%), Gaps = 7/215 (3%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAKS--ACEKVIRRDIA 242
R++ V+ VR+GVP R VW +L+G ++ Y ++ + E IR D+
Sbjct: 75 RSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLN 134
Query: 243 RTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQMPEEEAFA 300
RT+P++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+ EEE+F
Sbjct: 135 RTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFW 194
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
+L ++ + + D + P+M L L LV+ LP + + +L
Sbjct: 195 LLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFI 253
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
RI D +EG +I+F+VAL L+
Sbjct: 254 CLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 288
>BC062461-1|AAH62461.1| 317|Homo sapiens GRTP1 protein protein.
Length = 317
Score = 95.5 bits (227), Expect = 7e-19
Identities = 67/215 (31%), Positives = 106/215 (49%), Gaps = 7/215 (3%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAKS--ACEKVIRRDIA 242
R++ V+ VR+GVP R VW +L+G ++ Y ++ + E IR D+
Sbjct: 38 RSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLN 97
Query: 243 RTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQMPEEEAFA 300
RT+P++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+ EEE+F
Sbjct: 98 RTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFW 157
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
+L ++ + + D + P+M L L LV+ LP + + +L
Sbjct: 158 LLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFI 216
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
RI D +EG +I+F+VAL L+
Sbjct: 217 CLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 251
>AL136221-9|CAI13799.2| 336|Homo sapiens growth hormone regulated
TBC protein 1 protein.
Length = 336
Score = 95.5 bits (227), Expect = 7e-19
Identities = 67/215 (31%), Positives = 106/215 (49%), Gaps = 7/215 (3%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAKS--ACEKVIRRDIA 242
R++ V+ VR+GVP R VW +L+G ++ Y ++ + E IR D+
Sbjct: 57 RSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLN 116
Query: 243 RTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQMPEEEAFA 300
RT+P++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+ EEE+F
Sbjct: 117 RTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFW 176
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
+L ++ + + D + P+M L L LV+ LP + + +L
Sbjct: 177 LLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFI 235
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
RI D +EG +I+F+VAL L+
Sbjct: 236 CLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 270
>AL591849-3|CAI40161.1| 1178|Homo sapiens novel protein protein.
Length = 1178
Score = 94.7 bits (225), Expect = 1e-18
Identities = 61/224 (27%), Positives = 107/224 (47%), Gaps = 10/224 (4%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK-SACE---KVIRRD 240
R + RDLV +G+P RG +W L +G D + Y ++ C + I RD
Sbjct: 534 RTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERD 593
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ R+ PEH F+ G+ +L V+ AY+ + ++GYCQ + +LL+ EEEAF
Sbjct: 594 LRRSLPEHPAFQSDTGIS--ALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFW 651
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
+LV + ++ + D F + + E L+++ LP L H +F +S+ +
Sbjct: 652 LLVAVCER-MLPDYFNRRIIGALVDQAVFEELIRDHLPQLTEHMTDMTFFSSV-SLSWFL 709
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
A ++D F +GI+ + ++ LA+L + LL+
Sbjct: 710 TLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLT 753
>AL391315-4|CAI39548.1| 1178|Homo sapiens novel protein protein.
Length = 1178
Score = 94.7 bits (225), Expect = 1e-18
Identities = 61/224 (27%), Positives = 107/224 (47%), Gaps = 10/224 (4%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK-SACE---KVIRRD 240
R + RDLV +G+P RG +W L +G D + Y ++ C + I RD
Sbjct: 534 RTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERD 593
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ R+ PEH F+ G+ +L V+ AY+ + ++GYCQ + +LL+ EEEAF
Sbjct: 594 LRRSLPEHPAFQSDTGIS--ALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFW 651
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
+LV + ++ + D F + + E L+++ LP L H +F +S+ +
Sbjct: 652 LLVAVCER-MLPDYFNRRIIGALVDQAVFEELIRDHLPQLTEHMTDMTFFSSV-SLSWFL 709
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
A ++D F +GI+ + ++ LA+L + LL+
Sbjct: 710 TLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLT 753
>Z99127-4|CAI18934.1| 378|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 378
Score = 93.5 bits (222), Expect = 3e-18
Identities = 59/212 (27%), Positives = 100/212 (47%), Gaps = 6/212 (2%)
Query: 333 VQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL 392
++E LPDLH HF + +YA + I+D+ L EG+ I+F VAL
Sbjct: 1 MKEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVAL 60
Query: 393 ALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEY 450
ALL K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 61 ALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEY 120
Query: 451 TVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEET 506
++ + + ++ENR L++ V ++ D + E++
Sbjct: 121 QTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKA 180
Query: 507 FALDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 181 DVLNKELLLTKQRLVETEEEKRKQEEETAQLK 212
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 98 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 151
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 152 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 210
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 211 LK-EVFRKQLEKA 222
>BC071978-1|AAH71978.1| 502|Homo sapiens TBC1D2 protein protein.
Length = 502
Score = 93.5 bits (222), Expect = 3e-18
Identities = 74/287 (25%), Positives = 126/287 (43%), Gaps = 9/287 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 192 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 251
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 252 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 311
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 312 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 371
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG ++VF+ ALA+ + ++L L + Y K
Sbjct: 372 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL-QNGLEIYQYLRFFTKTI 430
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 431 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 476
>BC033071-1|AAH33071.2| 276|Homo sapiens GRTP1 protein protein.
Length = 276
Score = 93.5 bits (222), Expect = 3e-18
Identities = 66/211 (31%), Positives = 103/211 (48%), Gaps = 7/211 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK--LYASYIKAKS--ACEKVIRRDIARTYP 246
V+ VR+GVP R VW +L+G ++ Y ++ + E IR D+ RT+P
Sbjct: 1 VKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLNRTFP 60
Query: 247 EH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLMQMPEEEAFAVLVK 304
++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+ EEE+F +L
Sbjct: 61 DNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFWLLDA 120
Query: 305 IMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXX 364
++ + + D + P+M L L LV+ LP + + +L
Sbjct: 121 LVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFICLFV 179
Query: 365 XXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
RI D +EG +I+F+VAL L+
Sbjct: 180 DILPVETVLRIWDCLFNEGSKIIFRVALTLI 210
>BC028918-1|AAH28918.1| 468|Homo sapiens TBC1D2 protein protein.
Length = 468
Score = 93.5 bits (222), Expect = 3e-18
Identities = 74/287 (25%), Positives = 126/287 (43%), Gaps = 9/287 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 158 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 217
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 218 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 277
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 278 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 337
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG ++VF+ ALA+ + ++L L + Y K
Sbjct: 338 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL-QNGLEIYQYLRFFTKTI 396
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 397 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 442
>AL360081-1|CAH71884.1| 710|Homo sapiens TBC1 domain family, member
2 protein.
Length = 710
Score = 93.5 bits (222), Expect = 3e-18
Identities = 74/287 (25%), Positives = 126/287 (43%), Gaps = 9/287 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 400 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 459
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 460 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 519
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 520 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 579
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG ++VF+ ALA+ + ++L L + Y K
Sbjct: 580 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL-QNGLEIYQYLRFFTKTI 638
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 639 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 684
>AL161671-3|CAI16278.1| 378|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 378
Score = 93.5 bits (222), Expect = 3e-18
Identities = 59/212 (27%), Positives = 100/212 (47%), Gaps = 6/212 (2%)
Query: 333 VQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL 392
++E LPDLH HF + +YA + I+D+ L EG+ I+F VAL
Sbjct: 1 MKEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVAL 60
Query: 393 ALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEY 450
ALL K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 61 ALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEY 120
Query: 451 TVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEET 506
++ + + ++ENR L++ V ++ D + E++
Sbjct: 121 QTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKA 180
Query: 507 FALDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 181 DVLNKELLLTKQRLVETEEEKRKQEEETAQLK 212
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 98 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 151
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 152 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 210
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 211 LK-EVFRKQLEKA 222
>AL137073-10|CAI13894.1| 468|Homo sapiens TBC1 domain family,
member 2 protein.
Length = 468
Score = 93.5 bits (222), Expect = 3e-18
Identities = 74/287 (25%), Positives = 126/287 (43%), Gaps = 9/287 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 158 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 217
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 218 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 277
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 278 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 337
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG ++VF+ ALA+ + ++L L + Y K
Sbjct: 338 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL-QNGLEIYQYLRFFTKTI 396
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 397 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 442
>AL137073-1|CAI13883.1| 710|Homo sapiens TBC1 domain family, member
2 protein.
Length = 710
Score = 93.5 bits (222), Expect = 3e-18
Identities = 74/287 (25%), Positives = 126/287 (43%), Gaps = 9/287 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 400 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 459
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 460 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 519
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 520 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 579
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG ++VF+ ALA+ + ++L L + Y K
Sbjct: 580 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL-QNGLEIYQYLRFFTKTI 638
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 639 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 684
>AL136377-1|CAI22932.1| 378|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 378
Score = 93.5 bits (222), Expect = 3e-18
Identities = 59/212 (27%), Positives = 100/212 (47%), Gaps = 6/212 (2%)
Query: 333 VQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL 392
++E LPDLH HF + +YA + I+D+ L EG+ I+F VAL
Sbjct: 1 MKEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVAL 60
Query: 393 ALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEY 450
ALL K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 61 ALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEY 120
Query: 451 TVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEET 506
++ + + ++ENR L++ V ++ D + E++
Sbjct: 121 QTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKA 180
Query: 507 FALDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 181 DVLNKELLLTKQRLVETEEEKRKQEEETAQLK 212
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 98 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 151
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 152 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 210
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 211 LK-EVFRKQLEKA 222
>AK026105-1|BAB15361.1| 710|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22452 fis, clone HRC09667. ).
Length = 710
Score = 93.5 bits (222), Expect = 3e-18
Identities = 74/287 (25%), Positives = 126/287 (43%), Gaps = 9/287 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 400 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 459
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 460 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 519
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 520 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 579
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG ++VF+ ALA+ + ++L L + Y K
Sbjct: 580 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL-QNGLEIYQYLRFFTKTI 638
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 639 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 684
>AB019491-1|BAA77332.1| 378|Homo sapiens IDN4-GGTR8 protein.
Length = 378
Score = 93.5 bits (222), Expect = 3e-18
Identities = 59/212 (27%), Positives = 100/212 (47%), Gaps = 6/212 (2%)
Query: 333 VQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVAL 392
++E LPDLH HF + +YA + I+D+ L EG+ I+F VAL
Sbjct: 1 MKEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVAL 60
Query: 393 ALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEY 450
ALL K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 61 ALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEY 120
Query: 451 TVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEET 506
++ + + ++ENR L++ V ++ D + E++
Sbjct: 121 QTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKA 180
Query: 507 FALDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 181 DVLNKELLLTKQRLVETEEEKRKQEEETAQLK 212
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 98 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 151
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 152 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 210
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 211 LK-EVFRKQLEKA 222
>X63546-1|CAA45108.1| 786|Homo sapiens oncogene protein.
Length = 786
Score = 93.1 bits (221), Expect = 4e-18
Identities = 71/300 (23%), Positives = 133/300 (44%), Gaps = 14/300 (4%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W ++ WE+ +K ++ + D V +G+P + RG VW +L + K I
Sbjct: 75 SKWMEMLGEWET-YKHSSKLI-DRVYKGIPMNIRGPVWSVLLNIQEIKLKNPGRYQIMKE 132
Query: 228 KAKSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
+ K + E + I D+ T H FF+++ G Q LF ++ AYS ++ EVGYC+ I
Sbjct: 133 RGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNPEVGYCRDLSHI 192
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H + P+ + Q E++V + P H
Sbjct: 193 TALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHVVPKSQPKTMWH 252
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
+ + L R+ DV+L EG +++ + L + + L+
Sbjct: 253 QDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPITSIALKVQQKRLM 312
Query: 404 SLDMESILKYIQKE-LPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIA 462
+ ++ + A D +L + + KK+ + + + +EQG +A
Sbjct: 313 KTSRCGLWARLRNQFFDTWAMNDDTVLKHL----RASTKKLTRKQGDLPPPAKREQGSLA 368
>AY143550-1|AAN38838.1| 1406|Homo sapiens ubiquitin-specific
protease USP6 protein.
Length = 1406
Score = 93.1 bits (221), Expect = 4e-18
Identities = 71/300 (23%), Positives = 133/300 (44%), Gaps = 14/300 (4%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W ++ WE+ +K ++ + D V +G+P + RG VW +L + K I
Sbjct: 75 SKWMEMLGEWET-YKHSSKLI-DRVYKGIPMNIRGPVWSVLLNIQEIKLKNPGRYQIMKE 132
Query: 228 KAKSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
+ K + E + I D+ T H FF+++ G Q LF ++ AYS ++ EVGYC+ I
Sbjct: 133 RGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNPEVGYCRDLSHI 192
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H + P+ + Q E++V + P H
Sbjct: 193 TALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHVVPKSQPKTMWH 252
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
+ + L R+ DV+L EG +++ + L + + L+
Sbjct: 253 QDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPITSIALKVQQKRLM 312
Query: 404 SLDMESILKYIQKE-LPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIA 462
+ ++ + A D +L + + KK+ + + + +EQG +A
Sbjct: 313 KTSRCGLWARLRNQFFDTWAMNDDTVLKHL----RASTKKLTRKQGDLPPPAKREQGSLA 368
>Z99127-5|CAI18935.1| 377|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 377
Score = 92.7 bits (220), Expect = 5e-18
Identities = 59/210 (28%), Positives = 98/210 (46%), Gaps = 6/210 (2%)
Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
E LPDLH HF + +YA + I+D+ L EG+ I+F VALAL
Sbjct: 2 EQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALAL 61
Query: 395 LTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTV 452
L K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 62 LKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQT 121
Query: 453 IKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFA 508
++ + + ++ENR L++ V ++ D + E++
Sbjct: 122 MRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADV 181
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 182 LNKELLLTKQRLVETEEEKRKQEEETAQLK 211
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 97 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 150
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 151 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 209
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 210 LK-EVFRKQLEKA 221
>AL161671-4|CAI16279.1| 377|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 377
Score = 92.7 bits (220), Expect = 5e-18
Identities = 59/210 (28%), Positives = 98/210 (46%), Gaps = 6/210 (2%)
Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
E LPDLH HF + +YA + I+D+ L EG+ I+F VALAL
Sbjct: 2 EQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALAL 61
Query: 395 LTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTV 452
L K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 62 LKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQT 121
Query: 453 IKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFA 508
++ + + ++ENR L++ V ++ D + E++
Sbjct: 122 MRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADV 181
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 182 LNKELLLTKQRLVETEEEKRKQEEETAQLK 211
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 97 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 150
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 151 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 209
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 210 LK-EVFRKQLEKA 221
>AL136377-2|CAI22933.1| 377|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 377
Score = 92.7 bits (220), Expect = 5e-18
Identities = 59/210 (28%), Positives = 98/210 (46%), Gaps = 6/210 (2%)
Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
E LPDLH HF + +YA + I+D+ L EG+ I+F VALAL
Sbjct: 2 EQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALAL 61
Query: 395 LTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTV 452
L K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 62 LKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQT 121
Query: 453 IKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFA 508
++ + + ++ENR L++ V ++ D + E++
Sbjct: 122 MRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADV 181
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 182 LNKELLLTKQRLVETEEEKRKQEEETAQLK 211
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 97 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 150
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 151 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 209
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 210 LK-EVFRKQLEKA 221
>AB019489-1|BAA77330.1| 377|Homo sapiens IDN4-GGTR6 protein.
Length = 377
Score = 92.7 bits (220), Expect = 5e-18
Identities = 59/210 (28%), Positives = 98/210 (46%), Gaps = 6/210 (2%)
Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
E LPDLH HF + +YA + I+D+ L EG+ I+F VALAL
Sbjct: 2 EQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALAL 61
Query: 395 LTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTV 452
L K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 62 LKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQT 121
Query: 453 IKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQV----DRAEGEEETFA 508
++ + + ++ENR L++ V ++ D + E++
Sbjct: 122 MRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADV 181
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLE 538
L++E+ ++ V+ ++ +E L+
Sbjct: 182 LNKELLLTKQRLVETEEEKRKQEEETAQLK 211
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 97 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 150
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 151 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 209
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 210 LK-EVFRKQLEKA 221
>AC016738-3|AAY14824.1| 897|Homo sapiens unknown protein.
Length = 897
Score = 92.3 bits (219), Expect = 7e-18
Identities = 68/243 (27%), Positives = 112/243 (46%), Gaps = 15/243 (6%)
Query: 171 SLWG-RLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLL--AGVDTSPEKKLYASYI 227
SLW V + R + +R LV G+P RG +W L A D + Y + +
Sbjct: 234 SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLV 293
Query: 228 KAK--SAC--EKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
+ C + I RD+ R+ PEH F+ + G+ +L V+ AY+ + ++GYCQ
Sbjct: 294 EESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMN 351
Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
+ +LL+ EEEAF +LV + ++ + D F + + E L++ LP+L H
Sbjct: 352 ILTSVLLLYTKEEEAFWLLVAVCER-MLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEH 410
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPL--ACRIMDVFLSEGIEIVFKVALALLTLGKND 401
S +L + PL A ++D F +GI+ +F++ LA+L D
Sbjct: 411 MNDLS---ALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAED 467
Query: 402 LLS 404
L S
Sbjct: 468 LCS 470
>AB024057-1|BAA75489.1| 897|Homo sapiens vascular
Rab-GAP/TBC-containing protein protein.
Length = 897
Score = 92.3 bits (219), Expect = 7e-18
Identities = 68/243 (27%), Positives = 112/243 (46%), Gaps = 15/243 (6%)
Query: 171 SLWG-RLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLL--AGVDTSPEKKLYASYI 227
SLW V + R + +R LV G+P RG +W L A D + Y + +
Sbjct: 234 SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLV 293
Query: 228 KAK--SAC--EKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
+ C + I RD+ R+ PEH F+ + G+ +L V+ AY+ + ++GYCQ
Sbjct: 294 EESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMN 351
Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
+ +LL+ EEEAF +LV + ++ + D F + + E L++ LP+L H
Sbjct: 352 ILTSVLLLYTKEEEAFWLLVAVCER-MLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEH 410
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPL--ACRIMDVFLSEGIEIVFKVALALLTLGKND 401
S +L + PL A ++D F +GI+ +F++ LA+L D
Sbjct: 411 MNDLS---ALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAED 467
Query: 402 LLS 404
L S
Sbjct: 468 LCS 470
>AB017114-1|BAA76517.1| 733|Homo sapiens AD 3 protein.
Length = 733
Score = 92.3 bits (219), Expect = 7e-18
Identities = 68/243 (27%), Positives = 112/243 (46%), Gaps = 15/243 (6%)
Query: 171 SLWG-RLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLL--AGVDTSPEKKLYASYI 227
SLW V + R + +R LV G+P RG +W L A D + Y + +
Sbjct: 230 SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLV 289
Query: 228 KAK--SAC--EKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSG 283
+ C + I RD+ R+ PEH F+ + G+ +L V+ AY+ + ++GYCQ
Sbjct: 290 EESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMN 347
Query: 284 FIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
+ +LL+ EEEAF +LV + ++ + D F + + E L++ LP+L H
Sbjct: 348 ILTSVLLLYTKEEEAFWLLVAVCER-MLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEH 406
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPL--ACRIMDVFLSEGIEIVFKVALALLTLGKND 401
S +L + PL A ++D F +GI+ +F++ LA+L D
Sbjct: 407 MNDLS---ALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAED 463
Query: 402 LLS 404
L S
Sbjct: 464 LCS 466
>X63547-1|CAA45110.1| 376|Homo sapiens oncogene protein.
Length = 376
Score = 91.9 bits (218), Expect = 9e-18
Identities = 62/240 (25%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W ++ WE+ +K ++ + D V +G+P + RG VW +L + K I
Sbjct: 75 SKWMEMLGEWET-YKHSSKLI-DRVYKGIPMNIRGPVWSVLLNIQEIKLKNPGRYQIMKE 132
Query: 228 KAKSACEKV--IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
+ K + E + I D+ T H FF+++ G Q LF ++ AYS ++ EVGYC+ I
Sbjct: 133 RGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNPEVGYCRDLSHI 192
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H + P+ + Q E++V + P H
Sbjct: 193 TALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHVVPKSQPKTMWH 252
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLL 403
+ + L R+ DV+L EG +++ + L + + L+
Sbjct: 253 QDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPITSIALKVQQKRLM 312
>AK131086-1|BAC85136.1| 217|Homo sapiens FLJ00288 protein protein.
Length = 217
Score = 90.2 bits (214), Expect = 3e-17
Identities = 50/148 (33%), Positives = 74/148 (50%), Gaps = 1/148 (0%)
Query: 236 VIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPE 295
VI RD+ R +P H+ F + G GQ+ LF V+KAY+L+ E GYCQ I +LLM MP
Sbjct: 14 VIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPA 73
Query: 296 EEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYA 355
E+AF LV+I +++ + + + + L L +L+Q++ P H H Q LY
Sbjct: 74 EQAFWCLVQICEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYM 132
Query: 356 XXXXXXXXXXXXXXPLACRIMDVFLSEG 383
R+ D+F EG
Sbjct: 133 TEWFMCAFSRTLPWSSVLRVWDMFFCEG 160
>AK127020-1|BAC86789.1| 1015|Homo sapiens protein ( Homo sapiens
cDNA FLJ45076 fis, clone BRAWH3027574, weakly similar
to Homo sapiens vascular Rab-GAP/TBC-containing (VRP).
).
Length = 1015
Score = 89.8 bits (213), Expect = 4e-17
Identities = 64/225 (28%), Positives = 111/225 (49%), Gaps = 12/225 (5%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV----DTSP---EKKLYASYIKAKSACEKVIRR 239
R + R+LV +G+P RG +W LL+G T P E + S K A E+ I R
Sbjct: 351 RTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEE-IER 409
Query: 240 DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAF 299
D+ R+ PEH F+ + G+ +L V+ AY+ + +GYCQ + +LL+ EEEAF
Sbjct: 410 DLHRSLPEHPAFQNEMGIA--ALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAF 467
Query: 300 AVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
+LV + ++ + D + + + E L ++ +P L+ Q +++ +
Sbjct: 468 WLLVALCER-MLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTI-SLSWF 525
Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
A ++D F EGI+++F++ALA+L + LL+
Sbjct: 526 LTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLN 570
>AB020689-1|BAA74905.2| 1291|Homo sapiens KIAA0882 protein protein.
Length = 1291
Score = 89.8 bits (213), Expect = 4e-17
Identities = 64/225 (28%), Positives = 111/225 (49%), Gaps = 12/225 (5%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV----DTSP---EKKLYASYIKAKSACEKVIRR 239
R + R+LV +G+P RG +W LL+G T P E + S K A E+ I R
Sbjct: 529 RTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEE-IER 587
Query: 240 DIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAF 299
D+ R+ PEH F+ + G+ +L V+ AY+ + +GYCQ + +LL+ EEEAF
Sbjct: 588 DLHRSLPEHPAFQNEMGIA--ALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAF 645
Query: 300 AVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXX 359
+LV + ++ + D + + + E L ++ +P L+ Q +++ +
Sbjct: 646 WLLVALCER-MLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTI-SLSWF 703
Query: 360 XXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
A ++D F EGI+++F++ALA+L + LL+
Sbjct: 704 LTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLN 748
>BC018630-1|AAH18630.2| 140|Homo sapiens RABGAP1L protein protein.
Length = 140
Score = 88.6 bits (210), Expect = 9e-17
Identities = 47/125 (37%), Positives = 66/125 (52%), Gaps = 2/125 (1%)
Query: 335 ELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALAL 394
E LPDLH HF + +YA + I+D+ L EG+ I+F VALAL
Sbjct: 1 EQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALAL 60
Query: 395 LTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNLAYSVKVNPKKMKKLEKEYTV 452
L K DLL D E LK+ + +LP + A++ A M A ++KV KK+KK EKEY
Sbjct: 61 LKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQT 120
Query: 453 IKTKE 457
++ +
Sbjct: 121 MRESQ 125
>BC129994-1|AAI29995.1| 1232|Homo sapiens TBC1 domain family, member
9B (with GRAM domain) protein.
Length = 1232
Score = 87.8 bits (208), Expect = 1e-16
Identities = 64/228 (28%), Positives = 103/228 (45%), Gaps = 10/228 (4%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK----SACEKVIRRD 240
R R LV +G+P RG +W L +G + YA ++ S + I RD
Sbjct: 497 RTAKTRALVLKGIPESLRGELWLLFSGAWNEMVTHPGYYAELVEKSTGKYSLATEEIERD 556
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ R+ PEH F+ + LG +L V+ AY+ + +GYCQ + +LL+ EEEAF
Sbjct: 557 LHRSMPEHPAFQNE--LGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFW 614
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
+LV + ++ + D + + + E L ++ LP L Q +S+ +
Sbjct: 615 LLVALCER-MLPDYYNTRVVGALVDQGIFEELTRDFLPQLSEKMQDLGVISSI-SLSWFL 672
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
A I+D F EGI+++ +VALA+L LL E
Sbjct: 673 TLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQLLGCSDE 720
>AB014576-1|BAA31651.1| 1262|Homo sapiens KIAA0676 protein protein.
Length = 1262
Score = 87.8 bits (208), Expect = 1e-16
Identities = 64/228 (28%), Positives = 103/228 (45%), Gaps = 10/228 (4%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK----SACEKVIRRD 240
R R LV +G+P RG +W L +G + YA ++ S + I RD
Sbjct: 509 RTAKTRALVLKGIPESLRGELWLLFSGAWNEMVTHPGYYAELVEKSTGKYSLATEEIERD 568
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ R+ PEH F+ + LG +L V+ AY+ + +GYCQ + +LL+ EEEAF
Sbjct: 569 LHRSMPEHPAFQNE--LGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFW 626
Query: 301 VLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXX 360
+LV + ++ + D + + + E L ++ LP L Q +S+ +
Sbjct: 627 LLVALCER-MLPDYYNTRVVGALVDQGIFEELTRDFLPQLSEKMQDLGVISSI-SLSWFL 684
Query: 361 XXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDME 408
A I+D F EGI+++ +VALA+L LL E
Sbjct: 685 TLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQLLGCSDE 732
>BC071680-1|AAH71680.1| 549|Homo sapiens TBC1 domain family, member
3C protein.
Length = 549
Score = 87.0 bits (206), Expect = 3e-16
Identities = 59/227 (25%), Positives = 106/227 (46%), Gaps = 9/227 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W ++ +WE ++K + + D +G+P + RG +W +L ++ K I
Sbjct: 76 SKWVDMLGDWE-KYKSSRKLI-DRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKE 133
Query: 228 KAKSACEKVIR--RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
K K + E + R RDI+ T +H FF+++ G Q L +++ AY ++ EVGYC+ I
Sbjct: 134 KGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHI 193
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H ++ P+ + Q E++V P H
Sbjct: 194 AALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGH 253
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKV 390
+ L R+ DV+L EG + + +
Sbjct: 254 QDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
>AF540953-1|AAN33117.1| 549|Homo sapiens Rab GTPase-activating
protein PRC17 protein.
Length = 549
Score = 86.6 bits (205), Expect = 3e-16
Identities = 58/227 (25%), Positives = 106/227 (46%), Gaps = 9/227 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W ++ +WE ++K + + D +G+P + RG +W +L ++ K I
Sbjct: 76 SKWVDMLGDWE-KYKSSRKLI-DRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKE 133
Query: 228 KAKSACEKVIR--RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
K K + E + R RD++ T +H FF+++ G Q L +++ AY ++ EVGYC+ I
Sbjct: 134 KGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHI 193
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H ++ P+ + Q E++V P H
Sbjct: 194 AALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGH 253
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKV 390
+ L R+ DV+L EG + + +
Sbjct: 254 QDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
>BC058890-1|AAH58890.1| 346|Homo sapiens TBC1D3P2 protein protein.
Length = 346
Score = 86.2 bits (204), Expect = 5e-16
Identities = 57/220 (25%), Positives = 102/220 (46%), Gaps = 9/220 (4%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W +++ W++ +K + + D QG+P + RG +W +L ++ K I
Sbjct: 76 SKWVKMLGEWDT-YKNSRKLI-DRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKE 133
Query: 228 KAKSACEKVIRRD--IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
K K + E + + D ++ T H FF+++ G Q L ++ AY ++ EVGYC+ I
Sbjct: 134 KGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGTKQRELLYILLAYEEYNPEVGYCRDLSHI 193
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H ++ P+ + Q E++V LP H
Sbjct: 194 AALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSLPKTMWH 253
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEG 383
+ + L R+ DV+L EG
Sbjct: 254 QDKKDLCGQCSSLGCLIRILIDGISLGLTLRLWDVYLVEG 293
>AK131449-1|BAD18594.1| 599|Homo sapiens d) (GAPCENA). protein.
Length = 599
Score = 85.4 bits (202), Expect = 8e-16
Identities = 43/116 (37%), Positives = 61/116 (52%), Gaps = 1/116 (0%)
Query: 167 EDLWSLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPE-KKLYAS 225
E + WG L+S W R + + LVR GVP RG VWQLLAG + + Y
Sbjct: 467 EKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRI 526
Query: 226 YIKAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQG 281
I +S + I RDI RT+P HD+FK+ G GQ+SL+ + K + + ++ G
Sbjct: 527 LITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKVFHVKKKKDSILSG 582
>AK000173-1|BAA90990.1| 312|Homo sapiens protein ( Homo sapiens
cDNA FLJ20166 fis, clone COL09511. ).
Length = 312
Score = 83.8 bits (198), Expect = 2e-15
Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 9/205 (4%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAGVDTSPEKK---------LYASYIKAKSACEKVIRRDI 241
+++L+R G+PH R VW+ T K L ++ ++ K I D+
Sbjct: 107 LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDL 166
Query: 242 ARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAV 301
RT P + + G + L NV+ A+S + ++GYCQG +V + L+ + +E+AF
Sbjct: 167 LRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWC 226
Query: 302 LVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXX 361
LV I++ RD + ++ + +L+ E LP LH HF+ +L
Sbjct: 227 LVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLV 286
Query: 362 XXXXXXXXPLACRIMDVFLSEGIEI 386
+ +I D FL EG ++
Sbjct: 287 VFVDSVVSDILFKIWDSFLYEGPKV 311
>BC075809-1|AAH75809.1| 549|Homo sapiens TBC1 domain family, member
3G protein.
Length = 549
Score = 83.4 bits (197), Expect = 3e-15
Identities = 58/227 (25%), Positives = 104/227 (45%), Gaps = 9/227 (3%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W ++ +WE ++K + + D +G+P + RG +W +L ++ K I
Sbjct: 76 SKWVDMLGDWE-KYKSSRKLI-DRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKE 133
Query: 228 KAKSACEKVIR--RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
K K + E + R RDI+ T H FF+++ G Q L +++ AY ++ EVGYC+ I
Sbjct: 134 KGKRSSEHIQRIDRDISGTLRRHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHI 193
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H ++ P+ + Q E++V H
Sbjct: 194 AALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGH 253
Query: 344 FQSQSFSTSLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKV 390
+ L R+ DV+L EG + + +
Sbjct: 254 QDKKDLCGQCSPLGCLIRILIDRISLGLTLRLWDVYLVEGEQALMPI 300
>BC078140-1|AAH78140.1| 291|Homo sapiens TBC1D3 protein protein.
Length = 291
Score = 81.8 bits (193), Expect = 1e-14
Identities = 54/185 (29%), Positives = 95/185 (51%), Gaps = 10/185 (5%)
Query: 171 SLWGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDTSPEKKLYASYI--- 227
S W ++ +WE ++K + + D +G+P + RG +W +L + K I
Sbjct: 76 SKWVDMLGDWE-KYKSSRKLI-DRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKE 133
Query: 228 KAKSACEKVIR--RDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFI 285
K K + E + R RD++ T +H FF+++ G Q L +++ AY ++ EVGYC+ I
Sbjct: 134 KGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHI 193
Query: 286 VGLLLMQMPEEEAFAVLVKIM--QQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVH 343
L L+ +PEE+AF LV+++ ++H ++ P+ + Q E++V P H
Sbjct: 194 AALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGH 253
Query: 344 FQSQS 348
QS S
Sbjct: 254 -QSAS 257
>AL591502-1|CAI12579.1| 860|Homo sapiens TBC1 domain family, member
2 protein.
Length = 860
Score = 81.4 bits (192), Expect = 1e-14
Identities = 60/222 (27%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
+ R+ D FL EG ++VF+ ALA+ + ++L L
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL 839
>AL360081-3|CAH71886.1| 860|Homo sapiens TBC1 domain family, member
2 protein.
Length = 860
Score = 81.4 bits (192), Expect = 1e-14
Identities = 60/222 (27%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
+ R+ D FL EG ++VF+ ALA+ + ++L L
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL 839
>AL137073-2|CAI13884.1| 860|Homo sapiens TBC1 domain family, member
2 protein.
Length = 860
Score = 81.4 bits (192), Expect = 1e-14
Identities = 60/222 (27%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSL 405
+ R+ D FL EG ++VF+ ALA+ + ++L L
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRL 839
>BC112125-1|AAI12126.1| 257|Homo sapiens GRTP1 protein protein.
Length = 257
Score = 79.8 bits (188), Expect = 4e-14
Identities = 54/164 (32%), Positives = 82/164 (50%), Gaps = 3/164 (1%)
Query: 234 EKVIRRDIARTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLM 291
E IR D+ RT+P++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+
Sbjct: 21 EDAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILI 80
Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFST 351
EEE+F +L ++ + + D + P+M L L LV+ LP + +
Sbjct: 81 TNNEEESFWLLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLW 139
Query: 352 SLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
+L RI D +EG +I+F+VAL L+
Sbjct: 140 TLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 183
>BC112123-1|AAI12124.1| 257|Homo sapiens GRTP1 protein protein.
Length = 257
Score = 79.8 bits (188), Expect = 4e-14
Identities = 54/164 (32%), Positives = 82/164 (50%), Gaps = 3/164 (1%)
Query: 234 EKVIRRDIARTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLM 291
E IR D+ RT+P++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+
Sbjct: 21 EDAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILI 80
Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFST 351
EEE+F +L ++ + + D + P+M L L LV+ LP + +
Sbjct: 81 TNNEEESFWLLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLW 139
Query: 352 SLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
+L RI D +EG +I+F+VAL L+
Sbjct: 140 TLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 183
>AL136221-8|CAI13800.2| 266|Homo sapiens growth hormone regulated
TBC protein 1 protein.
Length = 266
Score = 79.8 bits (188), Expect = 4e-14
Identities = 54/164 (32%), Positives = 82/164 (50%), Gaps = 3/164 (1%)
Query: 234 EKVIRRDIARTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLM 291
E IR D+ RT+P++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+
Sbjct: 30 EDAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILI 89
Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFST 351
EEE+F +L ++ + + D + P+M L L LV+ LP + +
Sbjct: 90 TNNEEESFWLLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLW 148
Query: 352 SLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
+L RI D +EG +I+F+VAL L+
Sbjct: 149 TLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 192
>AK026127-1|BAB15368.1| 257|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22474 fis, clone HRC10568. ).
Length = 257
Score = 79.4 bits (187), Expect = 5e-14
Identities = 54/164 (32%), Positives = 82/164 (50%), Gaps = 3/164 (1%)
Query: 234 EKVIRRDIARTYPEH-DFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG-LLLM 291
E IR D+ RT+P++ F K D Q +L+NV+ AY H++ VGYCQG FI G L+L+
Sbjct: 21 EDAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLVLI 80
Query: 292 QMPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFST 351
EEE+F +L ++ + + D + P+M L L LV+ LP + +
Sbjct: 81 TNNEEESFWLLDALVGR-ILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLW 139
Query: 352 SLYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALL 395
+L RI D +EG +I+F+VAL L+
Sbjct: 140 TLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI 183
>BC050523-1|AAH50523.2| 385|Homo sapiens TBC1D10B protein protein.
Length = 385
Score = 78.6 bits (185), Expect = 9e-14
Identities = 50/153 (32%), Positives = 74/153 (48%), Gaps = 13/153 (8%)
Query: 258 GQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVKIMQQHRMRDMFKP 317
GQ+ L+ ++KAY+++ + GYCQ + +LLM MP E+AF LV+I D + P
Sbjct: 1 GQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQIC------DKYLP 54
Query: 318 SMAELGLCMFQLEN-----LVQELLPDLHVHFQSQSFSTSLYAXXXXXXXXXXXXXXPLA 372
GL QL+ L++ P H H + Q LY
Sbjct: 55 GYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASV 114
Query: 373 CRIMDVFLSEGIEIVFKVALALL--TLGKNDLL 403
R+ D+F EG++I+F+VAL LL TLG + L
Sbjct: 115 LRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKL 147
>AK074954-1|BAC11312.1| 265|Homo sapiens protein ( Homo sapiens
cDNA FLJ90473 fis, clone NT2RP3002571, highly similar to
TBC1 domain family member 1. ).
Length = 265
Score = 78.6 bits (185), Expect = 9e-14
Identities = 65/258 (25%), Positives = 115/258 (44%), Gaps = 6/258 (2%)
Query: 293 MPEEEAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTS 352
M EEEAF +L +M +R ++P M L + M+QL L+ + DL+ H + S
Sbjct: 1 MSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPS 60
Query: 353 LYAXXXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLD-MESIL 411
LYA R+ D+ +G E++FKVAL+LL K +L + +E+I+
Sbjct: 61 LYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIV 120
Query: 412 KYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQEN 471
+I+ LP +N + + + K+++ E EY V++ +E D + L ++ +
Sbjct: 121 DFIKSTLPNLGLVQMEKTINQVFEMDI-AKQLQAYEVEYHVLQ-EELIDSSPLSDNQRMD 178
Query: 472 RLLKQRVXXXXXXXXXXXXXXV-RGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVA 530
+L K V G++ E E L E L++A + ++ +
Sbjct: 179 KLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKL-LSSE-SKLKQAMLTLELERSAL 236
Query: 531 LDEIRSLEMTIAENNSRQ 548
L + L AE + R+
Sbjct: 237 LQTVEELRRRSAEPSDRE 254
Score = 33.1 bits (72), Expect = 4.5
Identities = 17/44 (38%), Positives = 29/44 (65%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
L++ +LR+ N+D+ ++L VA I+SLE TI + S +S L+
Sbjct: 180 LEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK 223
>Z99127-6|CAI18936.1| 358|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 358
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/170 (28%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
Query: 375 IMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNL 432
I+D+ L EG+ I+F VALALL K DLL D E LK+ + +LP + A++ A M
Sbjct: 23 IIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQ 82
Query: 433 AYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXX 492
A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 83 ACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHEL 142
Query: 493 VRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 143 VTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 192
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 78 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 131
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 132 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 190
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 191 LK-EVFRKQLEKA 202
>AL161671-5|CAI16280.1| 358|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 358
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/170 (28%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
Query: 375 IMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNL 432
I+D+ L EG+ I+F VALALL K DLL D E LK+ + +LP + A++ A M
Sbjct: 23 IIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQ 82
Query: 433 AYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXX 492
A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 83 ACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHEL 142
Query: 493 VRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 143 VTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 192
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 78 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 131
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 132 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 190
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 191 LK-EVFRKQLEKA 202
>AL136377-3|CAI22934.1| 358|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 358
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/170 (28%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
Query: 375 IMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNL 432
I+D+ L EG+ I+F VALALL K DLL D E LK+ + +LP + A++ A M
Sbjct: 23 IIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQ 82
Query: 433 AYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXX 492
A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 83 ACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHEL 142
Query: 493 VRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 143 VTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 192
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 78 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 131
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 132 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 190
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 191 LK-EVFRKQLEKA 202
>AK091248-1|BAC03620.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ33929 fis, clone CTONG2017458, moderately
similar to Homo sapiens mRNA for vascular
Rab-GAP/TBC-containing ).
Length = 340
Score = 76.6 bits (180), Expect = 4e-13
Identities = 46/168 (27%), Positives = 83/168 (49%), Gaps = 4/168 (2%)
Query: 237 IRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEE 296
I RD+ R+ PEH F+ G+ +L V+ AY+ + ++GYCQ + +LL+ EE
Sbjct: 26 IERDLRRSLPEHPAFQSDTGIS--ALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEE 83
Query: 297 EAFAVLVKIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAX 356
EAF +LV + ++ + D F + + E L+++ LP L H +F +S+ +
Sbjct: 84 EAFWLLVAVCER-MLPDYFNRRIIGALVDQAVFEELIKDHLPQLTEHMTDMTFFSSV-SL 141
Query: 357 XXXXXXXXXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLS 404
A ++D F +GI+ + ++ LA+L + LL+
Sbjct: 142 SWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLT 189
>AB019493-1|BAA77334.1| 358|Homo sapiens IDN4-GGTR9 protein.
Length = 358
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/170 (28%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
Query: 375 IMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNL 432
I+D+ L EG+ I+F VALALL K DLL D E LK+ + +LP + A++ A M
Sbjct: 23 IIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQ 82
Query: 433 AYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXX 492
A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 83 ACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHEL 142
Query: 493 VRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 143 VTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 192
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 78 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 131
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 132 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 190
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 191 LK-EVFRKQLEKA 202
>AB019492-1|BAA77333.2| 358|Homo sapiens IDN4-GGTR14 protein.
Length = 358
Score = 76.6 bits (180), Expect = 4e-13
Identities = 49/170 (28%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
Query: 375 IMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--FMNL 432
I+D+ L EG+ I+F VALALL K DLL D E LK+ + +LP + A++ A M
Sbjct: 23 IIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQ 82
Query: 433 AYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXX 492
A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 83 ACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHEL 142
Query: 493 VRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 143 VTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 192
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 78 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 131
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 132 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 190
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 191 LK-EVFRKQLEKA 202
>AK123957-1|BAC85735.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ41963 fis, clone PUAEN2006328, moderately
similar to Homo sapiens TBC1 domain family, member 8
(with GRAM ).
Length = 632
Score = 76.2 bits (179), Expect = 5e-13
Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 8/128 (6%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK-SACE---KVIRRD 240
R + RDLV +G+P RG +W L +GV D + Y ++ C + I RD
Sbjct: 476 RTKKTRDLVVRGIPETLRGELWMLFSGVVNDMATNPDYYTEVVEQSLGTCNLATEEIERD 535
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ R+ PEH F+ G+ +L V+ AY+ + ++GYCQ + +LL+ EEEAF
Sbjct: 536 LRRSLPEHPAFQSDTGIS--ALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFW 593
Query: 301 VLVKIMQQ 308
+LV + ++
Sbjct: 594 LLVAVCER 601
>AY026527-1|AAK07684.1| 917|Homo sapiens prostate antigen PARIS-1
protein.
Length = 917
Score = 75.4 bits (177), Expect = 8e-13
Identities = 71/287 (24%), Positives = 121/287 (42%), Gaps = 20/287 (6%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG + K L L L++ L++ K +
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKYNEKEILRLQN-------GLEIYQYLRFFTKTI----- 845
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 846 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 891
>AL591502-2|CAI12580.1| 917|Homo sapiens TBC1 domain family, member
2 protein.
Length = 917
Score = 75.4 bits (177), Expect = 8e-13
Identities = 71/287 (24%), Positives = 121/287 (42%), Gaps = 20/287 (6%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG + K L L L++ L++ K +
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKYNEKEILRLQN-------GLEIYQYLRFFTKTI----- 845
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 846 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 891
>AL360081-4|CAH71887.1| 917|Homo sapiens TBC1 domain family, member
2 protein.
Length = 917
Score = 75.4 bits (177), Expect = 8e-13
Identities = 71/287 (24%), Positives = 121/287 (42%), Gaps = 20/287 (6%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG + K L L L++ L++ K +
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKYNEKEILRLQN-------GLEIYQYLRFFTKTI----- 845
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 846 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 891
>AL137073-3|CAI13885.1| 917|Homo sapiens TBC1 domain family, member
2 protein.
Length = 917
Score = 75.4 bits (177), Expect = 8e-13
Identities = 71/287 (24%), Positives = 121/287 (42%), Gaps = 20/287 (6%)
Query: 191 VRDLVRQGVPHHFRGIVWQLLAG--VDTSPEKKLYASYIKAKSACE----KVIRRDIART 244
++ L+R GVP R VW+ L V Y + A E + I D+ RT
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRT 677
Query: 245 YPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLV 303
+P + F + L V+ A+S + +GYCQG + + L+ + EEE AF LV
Sbjct: 678 FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLV 737
Query: 304 KIMQQHRMRDMFKPSMAELGLCMFQLENLVQELLPDLHVHFQSQSFSTSLYAXXXXXXXX 363
I++ D + ++ + L++L+ E LP L H SL
Sbjct: 738 AIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 364 XXXXXXPLACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAE 423
+ R+ D FL EG + K L L L++ L++ K +
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKYNEKEILRLQN-------GLEIYQYLRFFTKTI----- 845
Query: 424 ADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE 470
++ MN+A++ +NP +MK+L + V + + + ++ L L+ E
Sbjct: 846 SNSRKLMNIAFN-DMNPFRMKQLRQLRMVHRERLEAELRELEQLKAE 891
>BC122564-1|AAI22565.1| 632|Homo sapiens TBC1 domain family, member
8B (with GRAM domain) protein.
Length = 632
Score = 74.5 bits (175), Expect = 1e-12
Identities = 41/128 (32%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 187 RNQWVRDLVRQGVPHHFRGIVWQLLAGV--DTSPEKKLYASYIKAK-SACE---KVIRRD 240
R + RDLV +G+P RG +W L +G D + Y ++ C + I RD
Sbjct: 476 RTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERD 535
Query: 241 IARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFA 300
+ R+ PEH F+ G+ +L V+ AY+ + ++GYCQ + +LL+ EEEAF
Sbjct: 536 LRRSLPEHPAFQSDTGIS--ALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFW 593
Query: 301 VLVKIMQQ 308
+LV + ++
Sbjct: 594 LLVAVCER 601
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 64.9 bits (151), Expect = 1e-09
Identities = 65/264 (24%), Positives = 123/264 (46%), Gaps = 20/264 (7%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + ++EL+ V+ ++ A L ++ S+L + LQE Q
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAE-KLQLQEQLQAETELC 896
Query: 664 VQSNVVSDIMATPKKLLRAW----------EGRSADMLKLDEELMTTRIREVEALTELKE 713
++ + + K+ L E L+ +++ M I+E+E E +E
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 714 LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERAL-QTRQREFQHKYADLES 772
+ ++LE +V+T ++ EE +++ E+ + L +E+ L + R EF + E
Sbjct: 957 SARQKLQLE---KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
K+K A ++N +A I +LE + E K + E+ T +L ++ D SD++ ELQ
Sbjct: 1014 KSK---SLAKLKNKHEAM-ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
Query: 832 QVAELKAEIMRLEAWKSRALGHTE 855
Q+AELK ++ + E AL E
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVE 1093
Score = 47.2 bits (107), Expect = 3e-04
Identities = 74/362 (20%), Positives = 150/362 (41%), Gaps = 20/362 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLA--------VALDEIRSLEMTIAENN--SRQSSLE 552
EEE A + E+ +R + + RL + ++++ E AE + L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+A Q+ EE+ L+ I ELE + + R
Sbjct: 904 ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
+ + E KL E + + L+D ++++ + + + E +S ++ +
Sbjct: 964 LEKVTTEAKLKKLEEEQ--IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
+ ++ E R K +EL TR R++E + +L ++ EL+ Q+ QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTR-RKLEG--DSTDLSDQIAELQAQIAELKMQL 1078
Query: 733 RRQDEE--ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
+++EE A L R +AA Q+ AL+ + RE + + ++L+ + E N +
Sbjct: 1079 AKKEEELQAALARVEEEAA-QKNMALK-KIRELESQISELQEDLESERASRNKAEKQKRD 1136
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLEAWKSR 849
ELE +E + + A + ELR+ + + +++ L+E+ +A+I + S+
Sbjct: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
Query: 850 AL 851
A+
Sbjct: 1197 AV 1198
Score = 46.0 bits (104), Expect = 6e-04
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 16/230 (6%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E LSL ++V + S++ L+E ++ Q + +A KK +
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED---- 1375
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQVQVSTNQLRRQDEEARLL 742
S L+ EE+ +++E L++ E ++ K+ + +T++Q + L + R
Sbjct: 1376 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY 802
NL+ ++ L ++ KYA+ +A+ E+ + + + A+ + E + +E
Sbjct: 1436 ACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495
Query: 803 KLKNEVMATEGELRNNNMDDSDR--------VRELQEQVAELKAEIMRLE 844
+ N+ TE E ++ DD + R L++QV E+K ++ LE
Sbjct: 1496 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
Score = 38.7 bits (86), Expect = 0.090
Identities = 76/442 (17%), Positives = 168/442 (38%), Gaps = 25/442 (5%)
Query: 416 KELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE----- 470
+EL + E +++A L K+KKLE+E +++ + + L
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 471 -NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEE-ETFALDREVQALRRANVDMQQRLA 528
N ++ + +R EE + L++ + L + D+ ++A
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 529 VALDEIRSLEMTIAENNSR-QSSLEGTESASGQKHEELARC--LQXXXXXXXXXXXXXXX 585
+I L+M +A+ Q++L E + QK+ L + L+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+L E ++L+ + D + + + K RE E N+ K L +
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK-REQEVNILKKTLEEEAKTHE 1184
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELM----TTR 701
Q Q+H Q Q + A +K + E ++ + L+ +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 702 IREVEALTELKELRLKVME---LETQVQVSTNQLRRQ-DEEARLLRENLDAALQRERALQ 757
+ + +L+EL++K E + T++ +L+ + D LL ++ + + +
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 758 TRQREFQHKYADLESKAKYE-SMQANIRNMEDAQ---RIAELETEVSEYKLKNEVMATEG 813
+ + Q L+ + + + S+ ++ +ED + R E E +++ L+ ++
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
Query: 814 ELRN--NNMDDSDRVRELQEQV 833
++ + M+DS E E+V
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEV 1386
Score = 38.3 bits (85), Expect = 0.12
Identities = 51/257 (19%), Positives = 113/257 (43%), Gaps = 21/257 (8%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDEL----IAVKLREAEANLSLKDLRQRVSELSESWQR 650
DE E K ++V A L+DE +AV R+ + + LKDL + +++
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARK-KLEMDLKDLEAHIDSANKNRDE 1635
Query: 651 HLQE-HKQEAPAAPVQSNVVS------DIMATPKKLLRAWEGRSADMLKLDEELMTTRIR 703
+++ K +A + +I+A K+ + + A+M++L EEL
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 704 EVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREF 763
+ +A E EL ++ + ++ + RR + L E L+ + R ++
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Query: 764 QHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS 823
+ + + E +++ + E+A++ +LE + E K+K + M EG +++
Sbjct: 1756 NLQIDQINTDLNLE--RSHAQKNENARQ--QLERQNKELKVKLQEM--EGTVKSKY---K 1806
Query: 824 DRVRELQEQVAELKAEI 840
+ L+ ++A+L+ ++
Sbjct: 1807 ASITALEAKIAQLEEQL 1823
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 64.9 bits (151), Expect = 1e-09
Identities = 65/264 (24%), Positives = 123/264 (46%), Gaps = 20/264 (7%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + ++EL+ V+ ++ A L ++ S+L + LQE Q
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAE-KLQLQEQLQAETELC 896
Query: 664 VQSNVVSDIMATPKKLLRAW----------EGRSADMLKLDEELMTTRIREVEALTELKE 713
++ + + K+ L E L+ +++ M I+E+E E +E
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 714 LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERAL-QTRQREFQHKYADLES 772
+ ++LE +V+T ++ EE +++ E+ + L +E+ L + R EF + E
Sbjct: 957 SARQKLQLE---KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
K+K A ++N +A I +LE + E K + E+ T +L ++ D SD++ ELQ
Sbjct: 1014 KSK---SLAKLKNKHEAM-ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
Query: 832 QVAELKAEIMRLEAWKSRALGHTE 855
Q+AELK ++ + E AL E
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVE 1093
Score = 47.2 bits (107), Expect = 3e-04
Identities = 74/362 (20%), Positives = 150/362 (41%), Gaps = 20/362 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLA--------VALDEIRSLEMTIAENN--SRQSSLE 552
EEE A + E+ +R + + RL + ++++ E AE + L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+A Q+ EE+ L+ I ELE + + R
Sbjct: 904 ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
+ + E KL E + + L+D ++++ + + + E +S ++ +
Sbjct: 964 LEKVTTEAKLKKLEEEQ--IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
+ ++ E R K +EL TR R++E + +L ++ EL+ Q+ QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTR-RKLEG--DSTDLSDQIAELQAQIAELKMQL 1078
Query: 733 RRQDEE--ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
+++EE A L R +AA Q+ AL+ + RE + + ++L+ + E N +
Sbjct: 1079 AKKEEELQAALARVEEEAA-QKNMALK-KIRELESQISELQEDLESERASRNKAEKQKRD 1136
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLEAWKSR 849
ELE +E + + A + ELR+ + + +++ L+E+ +A+I + S+
Sbjct: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
Query: 850 AL 851
A+
Sbjct: 1197 AV 1198
Score = 34.7 bits (76), Expect = 1.5
Identities = 71/388 (18%), Positives = 147/388 (37%), Gaps = 29/388 (7%)
Query: 416 KELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE----- 470
+EL + E +++A L K+KKLE+E +++ + + L
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 471 -NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEE-ETFALDREVQALRRANVDMQQRLA 528
N ++ + +R EE + L++ + L + D+ ++A
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 529 VALDEIRSLEMTIAENNSR-QSSLEGTESASGQKHEELARC--LQXXXXXXXXXXXXXXX 585
+I L+M +A+ Q++L E + QK+ L + L+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRV---- 641
+L E ++L+ + D + + + K RE E N+ K L +
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK-REQEVNILKKTLEEEAKTHE 1184
Query: 642 SELSESWQRHLQEHKQEAPAAPVQSNVVSDI-------------MATPKKLLRAWEGRSA 688
+++ E Q+H Q ++ A V +++ +A K+L +G S
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 689 -DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
K++ +L +++ E EL KV +L+ ++ T L + D ++ L ++
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 748 AALQRERALQTRQREFQHKYADLESKAK 775
A + + Q +E + L +K K
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLK 1332
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 64.9 bits (151), Expect = 1e-09
Identities = 65/264 (24%), Positives = 123/264 (46%), Gaps = 20/264 (7%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + ++EL+ V+ ++ A L ++ S+L + LQE Q
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAE-KLQLQEQLQAETELC 896
Query: 664 VQSNVVSDIMATPKKLLRAW----------EGRSADMLKLDEELMTTRIREVEALTELKE 713
++ + + K+ L E L+ +++ M I+E+E E +E
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 714 LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERAL-QTRQREFQHKYADLES 772
+ ++LE +V+T ++ EE +++ E+ + L +E+ L + R EF + E
Sbjct: 957 SARQKLQLE---KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
K+K A ++N +A I +LE + E K + E+ T +L ++ D SD++ ELQ
Sbjct: 1014 KSK---SLAKLKNKHEAM-ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
Query: 832 QVAELKAEIMRLEAWKSRALGHTE 855
Q+AELK ++ + E AL E
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVE 1093
Score = 47.2 bits (107), Expect = 3e-04
Identities = 74/362 (20%), Positives = 150/362 (41%), Gaps = 20/362 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLA--------VALDEIRSLEMTIAENN--SRQSSLE 552
EEE A + E+ +R + + RL + ++++ E AE + L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+A Q+ EE+ L+ I ELE + + R
Sbjct: 904 ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
+ + E KL E + + L+D ++++ + + + E +S ++ +
Sbjct: 964 LEKVTTEAKLKKLEEEQ--IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
+ ++ E R K +EL TR R++E + +L ++ EL+ Q+ QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTR-RKLEG--DSTDLSDQIAELQAQIAELKMQL 1078
Query: 733 RRQDEE--ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
+++EE A L R +AA Q+ AL+ + RE + + ++L+ + E N +
Sbjct: 1079 AKKEEELQAALARVEEEAA-QKNMALK-KIRELESQISELQEDLESERASRNKAEKQKRD 1136
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLEAWKSR 849
ELE +E + + A + ELR+ + + +++ L+E+ +A+I + S+
Sbjct: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
Query: 850 AL 851
A+
Sbjct: 1197 AV 1198
Score = 46.0 bits (104), Expect = 6e-04
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 16/230 (6%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E LSL ++V + S++ L+E ++ Q + +A KK +
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED---- 1375
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQVQVSTNQLRRQDEEARLL 742
S L+ EE+ +++E L++ E ++ K+ + +T++Q + L + R
Sbjct: 1376 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY 802
NL+ ++ L ++ KYA+ +A+ E+ + + + A+ + E + +E
Sbjct: 1436 ACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495
Query: 803 KLKNEVMATEGELRNNNMDDSDR--------VRELQEQVAELKAEIMRLE 844
+ N+ TE E ++ DD + R L++QV E+K ++ LE
Sbjct: 1496 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
Score = 38.7 bits (86), Expect = 0.090
Identities = 76/442 (17%), Positives = 168/442 (38%), Gaps = 25/442 (5%)
Query: 416 KELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE----- 470
+EL + E +++A L K+KKLE+E +++ + + L
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 471 -NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEE-ETFALDREVQALRRANVDMQQRLA 528
N ++ + +R EE + L++ + L + D+ ++A
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 529 VALDEIRSLEMTIAENNSR-QSSLEGTESASGQKHEELARC--LQXXXXXXXXXXXXXXX 585
+I L+M +A+ Q++L E + QK+ L + L+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+L E ++L+ + D + + + K RE E N+ K L +
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK-REQEVNILKKTLEEEAKTHE 1184
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELM----TTR 701
Q Q+H Q Q + A +K + E ++ + L+ +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 702 IREVEALTELKELRLKVME---LETQVQVSTNQLRRQ-DEEARLLRENLDAALQRERALQ 757
+ + +L+EL++K E + T++ +L+ + D LL ++ + + +
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 758 TRQREFQHKYADLESKAKYE-SMQANIRNMEDAQ---RIAELETEVSEYKLKNEVMATEG 813
+ + Q L+ + + + S+ ++ +ED + R E E +++ L+ ++
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
Query: 814 ELRN--NNMDDSDRVRELQEQV 833
++ + M+DS E E+V
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEV 1386
Score = 38.3 bits (85), Expect = 0.12
Identities = 51/257 (19%), Positives = 113/257 (43%), Gaps = 21/257 (8%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDEL----IAVKLREAEANLSLKDLRQRVSELSESWQR 650
DE E K ++V A L+DE +AV R+ + + LKDL + +++
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARK-KLEMDLKDLEAHIDSANKNRDE 1635
Query: 651 HLQE-HKQEAPAAPVQSNVVS------DIMATPKKLLRAWEGRSADMLKLDEELMTTRIR 703
+++ K +A + +I+A K+ + + A+M++L EEL
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 704 EVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREF 763
+ +A E EL ++ + ++ + RR + L E L+ + R ++
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Query: 764 QHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS 823
+ + + E +++ + E+A++ +LE + E K+K + M EG +++
Sbjct: 1756 NLQIDQINTDLNLE--RSHAQKNENARQ--QLERQNKELKVKLQEM--EGTVKSKY---K 1806
Query: 824 DRVRELQEQVAELKAEI 840
+ L+ ++A+L+ ++
Sbjct: 1807 ASITALEAKIAQLEEQL 1823
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 64.9 bits (151), Expect = 1e-09
Identities = 65/264 (24%), Positives = 123/264 (46%), Gaps = 20/264 (7%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + ++EL+ V+ ++ A L ++ S+L + LQE Q
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAE-KLQLQEQLQAETELC 896
Query: 664 VQSNVVSDIMATPKKLLRAW----------EGRSADMLKLDEELMTTRIREVEALTELKE 713
++ + + K+ L E L+ +++ M I+E+E E +E
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 714 LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERAL-QTRQREFQHKYADLES 772
+ ++LE +V+T ++ EE +++ E+ + L +E+ L + R EF + E
Sbjct: 957 SARQKLQLE---KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
K+K A ++N +A I +LE + E K + E+ T +L ++ D SD++ ELQ
Sbjct: 1014 KSK---SLAKLKNKHEAM-ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
Query: 832 QVAELKAEIMRLEAWKSRALGHTE 855
Q+AELK ++ + E AL E
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVE 1093
Score = 47.2 bits (107), Expect = 3e-04
Identities = 74/362 (20%), Positives = 150/362 (41%), Gaps = 20/362 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLA--------VALDEIRSLEMTIAENN--SRQSSLE 552
EEE A + E+ +R + + RL + ++++ E AE + L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+A Q+ EE+ L+ I ELE + + R
Sbjct: 904 ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
+ + E KL E + + L+D ++++ + + + E +S ++ +
Sbjct: 964 LEKVTTEAKLKKLEEEQ--IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
+ ++ E R K +EL TR R++E + +L ++ EL+ Q+ QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTR-RKLEG--DSTDLSDQIAELQAQIAELKMQL 1078
Query: 733 RRQDEE--ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
+++EE A L R +AA Q+ AL+ + RE + + ++L+ + E N +
Sbjct: 1079 AKKEEELQAALARVEEEAA-QKNMALK-KIRELESQISELQEDLESERASRNKAEKQKRD 1136
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLEAWKSR 849
ELE +E + + A + ELR+ + + +++ L+E+ +A+I + S+
Sbjct: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
Query: 850 AL 851
A+
Sbjct: 1197 AV 1198
Score = 38.3 bits (85), Expect = 0.12
Identities = 75/435 (17%), Positives = 163/435 (37%), Gaps = 23/435 (5%)
Query: 416 KELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE----- 470
+EL + E +++A L K+KKLE+E +++ + + L
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 471 -NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEE-ETFALDREVQALRRANVDMQQRLA 528
N ++ + +R EE + L++ + L + D+ ++A
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 529 VALDEIRSLEMTIAENNSR-QSSLEGTESASGQKHEELARC--LQXXXXXXXXXXXXXXX 585
+I L+M +A+ Q++L E + QK+ L + L+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+L E ++L+ + D + + + K RE E N+ K L +
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK-REQEVNILKKTLEEEAKTHE 1184
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV 705
Q Q+H Q Q + A +K + E + L E+ +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGE---LANEVKVLLQGKG 1241
Query: 706 EALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
++ + K++ ++ EL+ + ++ L+ LD ++ +
Sbjct: 1242 DSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTK 1301
Query: 766 KYADLESKAK--YESMQ-ANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD 822
++ LES+ + E +Q N + + + ++ ++E E + ++ E + E E ++N
Sbjct: 1302 DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR---EQLEEEEEAKHNL--- 1355
Query: 823 SDRVRELQEQVAELK 837
++ L QVA++K
Sbjct: 1356 EKQIATLHAQVADMK 1370
>BC047400-1|AAH47400.1| 250|Homo sapiens hypothetical protein
MGC51025 protein.
Length = 250
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/143 (27%), Positives = 73/143 (51%), Gaps = 7/143 (4%)
Query: 173 WGRLVSNWESEWKRRNQWVRDLVRQGVPHHFRGIVWQLLAGVDT----SPEK-KLYASYI 227
W +++++W R + + V + +P RG W LL +D +P K K+
Sbjct: 78 WQKMLADWTKY--RSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
Query: 228 KAKSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSGFIVG 287
K S I+ D++ T +H F ++ G+ Q+ L +++ AYS ++ EVGY + I
Sbjct: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
Query: 288 LLLMQMPEEEAFAVLVKIMQQHR 310
+LL+ +PEE+ F L +++ R
Sbjct: 196 ILLLCLPEEDVFWALTQLLAGER 218
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 64.9 bits (151), Expect = 1e-09
Identities = 65/264 (24%), Positives = 123/264 (46%), Gaps = 20/264 (7%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + ++EL+ V+ ++ A L ++ S+L + LQE Q
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAE-KLQLQEQLQAETELC 896
Query: 664 VQSNVVSDIMATPKKLLRAW----------EGRSADMLKLDEELMTTRIREVEALTELKE 713
++ + + K+ L E L+ +++ M I+E+E E +E
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 714 LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERAL-QTRQREFQHKYADLES 772
+ ++LE +V+T ++ EE +++ E+ + L +E+ L + R EF + E
Sbjct: 957 SARQKLQLE---KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
K+K A ++N +A I +LE + E K + E+ T +L ++ D SD++ ELQ
Sbjct: 1014 KSK---SLAKLKNKHEAM-ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
Query: 832 QVAELKAEIMRLEAWKSRALGHTE 855
Q+AELK ++ + E AL E
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVE 1093
Score = 47.2 bits (107), Expect = 3e-04
Identities = 74/362 (20%), Positives = 150/362 (41%), Gaps = 20/362 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLA--------VALDEIRSLEMTIAENN--SRQSSLE 552
EEE A + E+ +R + + RL + ++++ E AE + L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+A Q+ EE+ L+ I ELE + + R
Sbjct: 904 ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
+ + E KL E + + L+D ++++ + + + E +S ++ +
Sbjct: 964 LEKVTTEAKLKKLEEEQ--IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
+ ++ E R K +EL TR R++E + +L ++ EL+ Q+ QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTR-RKLEG--DSTDLSDQIAELQAQIAELKMQL 1078
Query: 733 RRQDEE--ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
+++EE A L R +AA Q+ AL+ + RE + + ++L+ + E N +
Sbjct: 1079 AKKEEELQAALARVEEEAA-QKNMALK-KIRELESQISELQEDLESERASRNKAEKQKRD 1136
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLEAWKSR 849
ELE +E + + A + ELR+ + + +++ L+E+ +A+I + S+
Sbjct: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
Query: 850 AL 851
A+
Sbjct: 1197 AV 1198
Score = 46.0 bits (104), Expect = 6e-04
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 16/230 (6%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E LSL ++V + S++ L+E ++ Q + +A KK +
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED---- 1375
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQVQVSTNQLRRQDEEARLL 742
S L+ EE+ +++E L++ E ++ K+ + +T++Q + L + R
Sbjct: 1376 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY 802
NL+ ++ L ++ KYA+ +A+ E+ + + + A+ + E + +E
Sbjct: 1436 ACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495
Query: 803 KLKNEVMATEGELRNNNMDDSDR--------VRELQEQVAELKAEIMRLE 844
+ N+ TE E ++ DD + R L++QV E+K ++ LE
Sbjct: 1496 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
Score = 38.7 bits (86), Expect = 0.090
Identities = 76/442 (17%), Positives = 168/442 (38%), Gaps = 25/442 (5%)
Query: 416 KELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE----- 470
+EL + E +++A L K+KKLE+E +++ + + L
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 471 -NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEE-ETFALDREVQALRRANVDMQQRLA 528
N ++ + +R EE + L++ + L + D+ ++A
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 529 VALDEIRSLEMTIAENNSR-QSSLEGTESASGQKHEELARC--LQXXXXXXXXXXXXXXX 585
+I L+M +A+ Q++L E + QK+ L + L+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+L E ++L+ + D + + + K RE E N+ K L +
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK-REQEVNILKKTLEEEAKTHE 1184
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELM----TTR 701
Q Q+H Q Q + A +K + E ++ + L+ +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 702 IREVEALTELKELRLKVME---LETQVQVSTNQLRRQ-DEEARLLRENLDAALQRERALQ 757
+ + +L+EL++K E + T++ +L+ + D LL ++ + + +
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 758 TRQREFQHKYADLESKAKYE-SMQANIRNMEDAQ---RIAELETEVSEYKLKNEVMATEG 813
+ + Q L+ + + + S+ ++ +ED + R E E +++ L+ ++
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
Query: 814 ELRN--NNMDDSDRVRELQEQV 833
++ + M+DS E E+V
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEV 1386
Score = 38.3 bits (85), Expect = 0.12
Identities = 51/257 (19%), Positives = 113/257 (43%), Gaps = 21/257 (8%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDEL----IAVKLREAEANLSLKDLRQRVSELSESWQR 650
DE E K ++V A L+DE +AV R+ + + LKDL + +++
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARK-KLEMDLKDLEAHIDSANKNRDE 1635
Query: 651 HLQE-HKQEAPAAPVQSNVVS------DIMATPKKLLRAWEGRSADMLKLDEELMTTRIR 703
+++ K +A + +I+A K+ + + A+M++L EEL
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 704 EVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREF 763
+ +A E EL ++ + ++ + RR + L E L+ + R ++
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Query: 764 QHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS 823
+ + + E +++ + E+A++ +LE + E K+K + M EG +++
Sbjct: 1756 NLQIDQINTDLNLE--RSHAQKNENARQ--QLERQNKELKVKLQEM--EGTVKSKY---K 1806
Query: 824 DRVRELQEQVAELKAEI 840
+ L+ ++A+L+ ++
Sbjct: 1807 ASITALEAKIAQLEEQL 1823
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 64.5 bits (150), Expect = 2e-09
Identities = 86/371 (23%), Positives = 149/371 (40%), Gaps = 29/371 (7%)
Query: 496 QVDRAEGEEETFALDR-EVQA-LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG 553
Q++ + E T A + ++QA + + Q+ A L E E + +S + L+
Sbjct: 414 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQS 473
Query: 554 TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV 613
+ S Q EEL + Q I + + E L++Q +
Sbjct: 474 SISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEK-- 531
Query: 614 AHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
Q +L ++ +A+ + LR +V +LS S ++ Q+ K+ A + +
Sbjct: 532 ---QAQLAQTLQQQEQAS---QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQL 585
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVM---ELETQVQVSTN 730
AT A E R A + + D L E E +L+ L+ ++ E Q S
Sbjct: 586 AT------AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVT 639
Query: 731 QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
Q +R+ E E L A ++ R Q E Q + A+LE + + E +A + +
Sbjct: 640 QAQREKAELSRKVEELQACVETARQ---EQHEAQAQVAELELQLRSEQQKAT-----EKE 691
Query: 791 RIAELETEVSEY--KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKS 848
R+A+ + ++ E LK + T+G L +D + E Q ++ELKAE L
Sbjct: 692 RVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK 751
Query: 849 RALGHTELSRA 859
R E RA
Sbjct: 752 RERKELEEERA 762
Score = 46.8 bits (106), Expect = 3e-04
Identities = 62/223 (27%), Positives = 101/223 (45%), Gaps = 24/223 (10%)
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
EL ++ EA L++LRQ V +L E + +EH A + QS T K
Sbjct: 1065 ELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEH---ASGSGAQSEAAGRTEPTGPK 1121
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
L E A++ KL+++ + + L+ R E ++ ++ QL + +E
Sbjct: 1122 L----EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQE 1177
Query: 739 ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQR----IAE 794
+ L A+ QRE A F+ K D SKA+ E R ++A+R I+
Sbjct: 1178 LGHSQSAL-ASAQRELA------AFRTKVQD-HSKAEDEWKAQVARGRQEAERKNSLISS 1229
Query: 795 LETEVSEYKLKNEVMATEG---ELRNNNMDDSDRVRELQEQVA 834
LE EVS L +V+ EG EL+ M +S++ ++L+E A
Sbjct: 1230 LEEEVS--ILNRQVLEKEGESKELKRLVMAESEKSQKLEESCA 1270
Score = 42.3 bits (95), Expect = 0.007
Identities = 85/362 (23%), Positives = 151/362 (41%), Gaps = 32/362 (8%)
Query: 500 AEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASG 559
A EE A RE A + +++ A L EI ++ +A N +R S+ A
Sbjct: 586 ATAAEEREASLRERDAALKQLEALEKEKAAKL-EILQQQLQVA-NEARDSAQTSVTQAQR 643
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENEN-KSLRRQRVDNNVAHLQD 618
+K EL+R ++ +L +E K+ ++RV LQ+
Sbjct: 644 EK-AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQE 702
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSN----VVSDIMA 674
+L A+K SL++ ++R ++ E QR + E K E + Q + + A
Sbjct: 703 QLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERA 762
Query: 675 TPK----KLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTN 730
K +LL+ E A+ L EL + A +E ++L V E+ +
Sbjct: 763 GRKGLEARLLQLGEAHQAETEVLRRELAEAMAAQHTAESECEQL---VKEVAAWRDGYED 819
Query: 731 QLRRQDEEARLLRENLDAALQR-ERALQTRQREFQHKYADLESKAKYE-SMQANIRNMED 788
+ + + + +E L + E+A Q Q E + K A +ES ++ + S Q N
Sbjct: 820 SQQEEAQYGAMFQEQLMTLKEECEKARQELQ-EAKEKVAGIESHSELQISRQQN------ 872
Query: 789 AQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKS 848
++AEL ++ + +V E E+R + +D + LQE++A E+ RLE
Sbjct: 873 --KLAELHANLA--RALQQVQ--EKEVRAQKL--ADDLSTLQEKMAATSKEVARLETLVR 924
Query: 849 RA 850
+A
Sbjct: 925 KA 926
Score = 37.5 bits (83), Expect = 0.21
Identities = 83/375 (22%), Positives = 143/375 (38%), Gaps = 17/375 (4%)
Query: 447 EKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEET 506
++E ++ E I L LRQ + LK+++ +
Sbjct: 1063 DQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKL 1122
Query: 507 FALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELA 566
AL EV L + QQ A +L+ RSLE A R S+LE + +K +EL
Sbjct: 1123 EALRAEVSKLEQ-QCQKQQEQADSLE--RSLEAERASRAERDSALETLQGQLEEKAQELG 1179
Query: 567 RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRR--QRVDNNVAHLQDELIAVK 624
Q DE + + R+ +R ++ ++ L++E+ +
Sbjct: 1180 HS-QSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILN 1238
Query: 625 LREAEANLSLKDLRQRVSELSESWQRHLQEH----KQEAPA-APVQSNVVSDIMATPKKL 679
+ E K+L++ V SE Q+ L+E +Q PA P N +
Sbjct: 1239 RQVLEKEGESKELKRLVMAESEKSQK-LEESCACCRQRQPATVPELQNAALLCGRRCRAS 1297
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEA 739
R E + L +EL + R E ELK + K + E +ST QL +A
Sbjct: 1298 GREAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQ--ALSTLQLEHTSTQA 1355
Query: 740 RLLRENLDAA-LQRERALQTRQREFQHKYADLESKAKYESMQAN-IRNMEDAQRIAELET 797
L+ E L A L ++ + E +H+ +SK ++A +R + + L
Sbjct: 1356 -LVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQ 1414
Query: 798 EVSEYKLKNEVMATE 812
+V+E + + + E
Sbjct: 1415 KVAEQERTAQQLRAE 1429
Score = 36.3 bits (80), Expect = 0.48
Identities = 90/360 (25%), Positives = 144/360 (40%), Gaps = 50/360 (13%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAEN--NSRQSSLEGTESASG- 559
E E L +EV A R D QQ A + MT+ E +RQ E E +G
Sbjct: 800 ESECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGI 859
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDE 619
+ H EL Q + + K +R Q++ ++++ LQ++
Sbjct: 860 ESHSELQISRQQNKLAELHANLARALQ-----------QVQEKEVRAQKLADDLSTLQEK 908
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
+ A A L+ L ++ E E+ R L K+ A A Q +
Sbjct: 909 MAATSKEVAR----LETLVRKAGEQQETASRELV--KEPARAGDRQP-----------EW 951
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEAL-TELKELRLKVMELETQVQVSTNQLRRQDEE 738
L +GR + + M RE E + EL+ LR +ME + Q Q Q R E
Sbjct: 952 LEEQQGRQFCSTQAALQAME---REAEQMGNELERLRAALMESQGQQQEERGQQER--EV 1006
Query: 739 ARLLRE--NLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
ARL +E A L E+A + + E + + A E + ++ ++Q + A + E E
Sbjct: 1007 ARLTQERGRAQADLALEKAARA-ELEMRLQNALNEQRVEFATLQEAL-----AHALTEKE 1060
Query: 797 TEVSEY-KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
+ E KL+ A EL + V++L+EQ+A+ + E +S A G TE
Sbjct: 1061 GKDQELAKLRGLEAAQIKELE----ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTE 1116
Score = 33.9 bits (74), Expect = 2.6
Identities = 46/236 (19%), Positives = 103/236 (43%), Gaps = 12/236 (5%)
Query: 630 ANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRA-WEGRSA 688
ANL + L + + E + + L + +A + + A +++ A +EG
Sbjct: 1458 ANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV 1517
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR---RQDEEARLLREN 745
+L EE + + +++EL K+ + + +V +L+ Q E++ +
Sbjct: 1518 KVL---EERQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR 1574
Query: 746 LDAALQRERA-LQTRQREFQHKYADLE-SKAKYES-MQANIRNMEDAQRIAELETEVSEY 802
A L +A L +++ +H +E +K Y++ Q N E + + +L+ E E
Sbjct: 1575 FQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKEL 1634
Query: 803 KLKNEVMATEGELRNNNMDDSDRV-RELQEQVAELKAEIMRLEAWKSRALGHTELS 857
+ + E + E + ++++ R L QV L+A++ + + R LG +++
Sbjct: 1635 RAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ-QLRDLGKFQVA 1689
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 64.5 bits (150), Expect = 2e-09
Identities = 86/371 (23%), Positives = 149/371 (40%), Gaps = 29/371 (7%)
Query: 496 QVDRAEGEEETFALDR-EVQA-LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG 553
Q++ + E T A + ++QA + + Q+ A L E E + +S + L+
Sbjct: 414 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQS 473
Query: 554 TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV 613
+ S Q EEL + Q I + + E L++Q +
Sbjct: 474 SISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEK-- 531
Query: 614 AHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
Q +L ++ +A+ + LR +V +LS S ++ Q+ K+ A + +
Sbjct: 532 ---QAQLAQTLQQQEQAS---QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQL 585
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVM---ELETQVQVSTN 730
AT A E R A + + D L E E +L+ L+ ++ E Q S
Sbjct: 586 AT------AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVT 639
Query: 731 QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
Q +R+ E E L A ++ R Q E Q + A+LE + + E +A + +
Sbjct: 640 QAQREKAELSRKVEELQACVETARQ---EQHEAQAQVAELELQLRSEQQKAT-----EKE 691
Query: 791 RIAELETEVSEY--KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKS 848
R+A+ + ++ E LK + T+G L +D + E Q ++ELKAE L
Sbjct: 692 RVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK 751
Query: 849 RALGHTELSRA 859
R E RA
Sbjct: 752 RERKELEEERA 762
Score = 50.4 bits (115), Expect = 3e-05
Identities = 64/228 (28%), Positives = 106/228 (46%), Gaps = 24/228 (10%)
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
EL ++ EA L++LRQ V +L E + +EH A + QS T K
Sbjct: 1065 ELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEH---ASGSGAQSEAAGRTEPTGPK 1121
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
L E A++ KL+++ + + L+ R E ++ ++ QL + +E
Sbjct: 1122 L----EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQE 1177
Query: 739 ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQR----IAE 794
+ L A+ QRE A F+ K D SKA+ E R ++A+R I+
Sbjct: 1178 LGHSQSAL-ASAQRELA------AFRTKVQD-HSKAEDEWKAQVARGRQEAERKNSLISS 1229
Query: 795 LETEVSEYKLKNEVMATEG---ELRNNNMDDSDRVRELQEQVAELKAE 839
LE EVS L +V+ EG EL+ M +S++ ++L+E++ L+AE
Sbjct: 1230 LEEEVS--ILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAE 1275
Score = 42.3 bits (95), Expect = 0.007
Identities = 80/357 (22%), Positives = 144/357 (40%), Gaps = 22/357 (6%)
Query: 500 AEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASG 559
A EE A RE A + +++ A L EI ++ +A N +R S+ A
Sbjct: 586 ATAAEEREASLRERDAALKQLEALEKEKAAKL-EILQQQLQVA-NEARDSAQTSVTQAQR 643
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENEN-KSLRRQRVDNNVAHLQD 618
+K EL+R ++ +L +E K+ ++RV LQ+
Sbjct: 644 EK-AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQE 702
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
+L A+K SL++ ++R ++ E QR + E K E ++V K+
Sbjct: 703 QLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAET------RSLVEQHKRERKE 756
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALT-ELKELRLKVMELETQVQVSTNQL---RR 734
L GR +L ++L E E L EL E E++ + ++ R
Sbjct: 757 LEEERAGRKGLEARL-QQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRE 815
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADL-ESKAKYESMQANIRNMEDAQRIA 793
+ E+++ A Q + L T + E + +L E+K K ++++ Q+
Sbjct: 816 RYEDSQQEEAQYGAMFQEQ--LMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNE 873
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
E + + +V E E+R + +D + LQE++A E+ RLE +A
Sbjct: 874 LAELHANLARALQQVQ--EKEVRAQKL--ADDLSTLQEKMAATSKEVARLETLVRKA 926
Score = 37.1 bits (82), Expect = 0.28
Identities = 74/420 (17%), Positives = 159/420 (37%), Gaps = 30/420 (7%)
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
+ Q D+A+ + R E + Q + + EG+++ A R ++A
Sbjct: 1015 RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 1074
Query: 516 LRRANVD-MQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXX 574
+ ++ ++Q + +++ E A + QS G +G K E L +
Sbjct: 1075 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRA--EVSKL 1132
Query: 575 XXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSL 634
+ + + + + EL + A A L
Sbjct: 1133 EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQREL 1192
Query: 635 KDLRQRV---SELSESWQRHLQEHKQEAPAA-PVQSNVVSDIMATPKKLLRAWEGRSADM 690
R +V S+ + W+ + +QEA + S++ ++ +++L EG S ++
Sbjct: 1193 AAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEK-EGESKEL 1251
Query: 691 LKL------DEELMTTRIREVEALTELKELRL--KVMELETQVQVSTNQLRRQDEEARLL 742
+L + + R+R ++A T R + L +VQ + +Q + L
Sbjct: 1252 KRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENL 1311
Query: 743 RENLDAALQRERALQTRQREFQHKYADLES-----KAKYESMQANIRNMEDAQRIA---E 794
R+ L + +R L + +Q K+ E + ++ S QA + + A+ + +
Sbjct: 1312 RQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQ 1371
Query: 795 LETEVSEYKLKNEVMATE---GELRNNNMDDSDRVRE---LQEQVAELKAEIMRLEAWKS 848
E +E + + E+ ++ G LR + + E L+++VAE + +L A K+
Sbjct: 1372 AEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKA 1431
Score = 36.7 bits (81), Expect = 0.36
Identities = 90/360 (25%), Positives = 144/360 (40%), Gaps = 50/360 (13%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAEN--NSRQSSLEGTESASG- 559
E E L +EV A R D QQ A + MT+ E +RQ E E +G
Sbjct: 800 ESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGI 859
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDE 619
+ H EL Q + + K +R Q++ ++++ LQ++
Sbjct: 860 ESHSELQISRQQNELAELHANLARALQ-----------QVQEKEVRAQKLADDLSTLQEK 908
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
+ A A L+ L ++ E E+ R L K+ A A Q +
Sbjct: 909 MAATSKEVAR----LETLVRKAGEQQETASRELV--KEPARAGDRQP-----------EW 951
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEAL-TELKELRLKVMELETQVQVSTNQLRRQDEE 738
L +GR + + M RE E + EL+ LR +ME + Q Q Q R E
Sbjct: 952 LEEQQGRQFCSTQAALQAME---REAEQMGNELERLRAALMESQGQQQEERGQQER--EV 1006
Query: 739 ARLLRE--NLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
ARL +E A L E+A + + E + + A E + ++ ++Q + A + E E
Sbjct: 1007 ARLTQERGRAQADLALEKAARA-ELEMRLQNALNEQRVEFATLQEAL-----AHALTEKE 1060
Query: 797 TEVSEY-KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
+ E KL+ A EL + V++L+EQ+A+ + E +S A G TE
Sbjct: 1061 GKDQELAKLRGLEAAQIKELE----ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTE 1116
Score = 36.3 bits (80), Expect = 0.48
Identities = 43/229 (18%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK-KLLRAWEG 685
E E + + + Q ++ + + L E ++EA + + V++ K K+L +
Sbjct: 1466 EVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQR 1525
Query: 686 RSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR---QDEEARLL 742
+ KL ++ + + E +++EL K+ + + +V +L+ Q E++
Sbjct: 1526 FQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQE 1585
Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY 802
+ L A L +A +++ + Y KAK +N E +++ LE +
Sbjct: 1586 AQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLE----QL 1641
Query: 803 KLKNEVMATEGELRNNNMDDSD-RVRELQEQVAELKAEIMRLEAWKSRA 850
+ +N+ + E E + + + + +E ++ L A++ LEA + A
Sbjct: 1642 QKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHA 1690
Score = 33.9 bits (74), Expect = 2.6
Identities = 64/369 (17%), Positives = 143/369 (38%), Gaps = 15/369 (4%)
Query: 498 DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAEN-NSRQSSLEGTES 556
++ E + + L+ ++++ ++ + ++R+A D+++ + E+ + SLE +
Sbjct: 665 EQHEAQAQVAELELQLRSEQQKATE-KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKR 723
Query: 557 ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH- 615
+ EE RC+ ++E K L + AH
Sbjct: 724 RAADALEEQQRCISELKAETRSLVEQHKRERKE----LEEERAGRKGLEARLQQLGEAHQ 779
Query: 616 LQDELIAVKLREAEA--NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
+ E++ +L EA A + + + Q V E++ +W+ ++ +QE A + +M
Sbjct: 780 AETEVLRRELAEAMAAQHTAESECEQLVKEVA-AWRERYEDSQQEE--AQYGAMFQEQLM 836
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
++ +A + K+ + ++ EL EL + QVQ + +
Sbjct: 837 TLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQ 896
Query: 734 RQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN---MEDAQ 790
+ ++ L+E + A + L+T R+ + + E +A R +E+ Q
Sbjct: 897 KLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQ 956
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
T+ + ++ E EL + + QE+ + + E+ RL + RA
Sbjct: 957 GRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRA 1016
Query: 851 LGHTELSRA 859
L +A
Sbjct: 1017 QADLALEKA 1025
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/167 (29%), Positives = 89/167 (53%), Gaps = 9/167 (5%)
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
L+ +++ M I+E+E E +E + ++LE +V+T ++ EE +++ E+ + L
Sbjct: 220 LQAEKKKMQQNIQELEEQLEEEESARQKLQLE---KVTTEAKLKKLEEEQIILEDQNCKL 276
Query: 751 QRERAL-QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEV 808
+E+ L + R EF + E K+K A ++N +A I +LE + E K + E+
Sbjct: 277 AKEKKLLEDRIAEFTTNLTEEEEKSK---SLAKLKNKHEAM-ITDLEERLRREEKQRQEL 332
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
T +L ++ D SD++ ELQ Q+AELK ++ + E AL E
Sbjct: 333 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVE 379
Score = 47.2 bits (107), Expect = 3e-04
Identities = 74/362 (20%), Positives = 150/362 (41%), Gaps = 20/362 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLA--------VALDEIRSLEMTIAENN--SRQSSLE 552
EEE A + E+ +R + + RL + ++++ E AE + L
Sbjct: 130 EEEMMAKEEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 189
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+A Q+ EE+ L+ I ELE + + R
Sbjct: 190 ARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 249
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
+ + E KL E + + L+D ++++ + + + E +S ++ +
Sbjct: 250 LEKVTTEAKLKKLEEEQ--IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 307
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
+ ++ E R K +EL TR R++E + +L ++ EL+ Q+ QL
Sbjct: 308 KNKHEAMITDLEERLRREEKQRQELEKTR-RKLEG--DSTDLSDQIAELQAQIAELKMQL 364
Query: 733 RRQDEE--ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
+++EE A L R +AA Q+ AL+ + RE + + ++L+ + E N +
Sbjct: 365 AKKEEELQAALARVEEEAA-QKNMALK-KIRELESQISELQEDLESERASRNKAEKQKRD 422
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLEAWKSR 849
ELE +E + + A + ELR+ + + +++ L+E+ +A+I + S+
Sbjct: 423 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 482
Query: 850 AL 851
A+
Sbjct: 483 AV 484
Score = 47.2 bits (107), Expect = 3e-04
Identities = 49/230 (21%), Positives = 105/230 (45%), Gaps = 15/230 (6%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E LSL ++V + S++ L+E ++EA + ++ + A + + E
Sbjct: 606 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQ--IATLHAQVADMKKKMED- 662
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQVQVSTNQLRRQDEEARLL 742
S L+ EE+ +++E L++ E ++ K+ + +T++Q + L + R
Sbjct: 663 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 722
Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY 802
NL+ ++ L ++ KYA+ +A+ E+ + + + A+ + E + +E
Sbjct: 723 ACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 782
Query: 803 KLKNEVMATEGELRNNNMDDSDR--------VRELQEQVAELKAEIMRLE 844
+ N+ TE E ++ DD + R L++QV E+K ++ LE
Sbjct: 783 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 832
Score = 40.7 bits (91), Expect = 0.022
Identities = 75/438 (17%), Positives = 168/438 (38%), Gaps = 22/438 (5%)
Query: 416 KELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQE----- 470
+EL + E +++A L K+KKLE+E +++ + + L
Sbjct: 232 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 291
Query: 471 -NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEE-ETFALDREVQALRRANVDMQQRLA 528
N ++ + +R EE + L++ + L + D+ ++A
Sbjct: 292 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 351
Query: 529 VALDEIRSLEMTIAENNSR-QSSLEGTESASGQKHEELARC--LQXXXXXXXXXXXXXXX 585
+I L+M +A+ Q++L E + QK+ L + L+
Sbjct: 352 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 411
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+L E ++L+ + D + + + K RE E N+ K L +
Sbjct: 412 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK-REQEVNILKKTLEEEAKTHE 470
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV 705
Q Q+H Q Q + A +K + E ++ + +++ R+
Sbjct: 471 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN-EVKVLLQGGRDS 529
Query: 706 EALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
E + K++ ++ EL+ + ++ L+ LD ++ +
Sbjct: 530 E--HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTK 587
Query: 766 KYADLESKAK--YESMQ-ANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD 822
++ LES+ + E +Q N + + + ++ ++E E + ++ E + E E +N++
Sbjct: 588 DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR---EQLEEEEEEAKHNLE- 643
Query: 823 SDRVRELQEQVAELKAEI 840
++ L QVA++K ++
Sbjct: 644 -KQIATLHAQVADMKKKM 660
Score = 37.9 bits (84), Expect = 0.16
Identities = 51/257 (19%), Positives = 112/257 (43%), Gaps = 21/257 (8%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDEL----IAVKLREAEANLSLKDLRQRVSELSESWQR 650
DE E K ++V A L+DE +AV R+ + + LKDL + +++
Sbjct: 864 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARK-KLEMDLKDLEAHIDSANKNRDE 922
Query: 651 HLQE-HKQEAPAAPVQSNVVS------DIMATPKKLLRAWEGRSADMLKLDEELMTTRIR 703
+++ K +A + +I+A K+ + + A+M++L EEL
Sbjct: 923 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 982
Query: 704 EVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREF 763
+ +A E EL ++ + ++ + RR + L E L+ + R ++
Sbjct: 983 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1042
Query: 764 QHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS 823
+ + + E + + + E+A++ +LE + E K+K + M EG +++
Sbjct: 1043 NLQIDQINADLNLE--RGHAQKNENARQ--QLERQNKELKVKLQEM--EGTVKSKY---K 1093
Query: 824 DRVRELQEQVAELKAEI 840
+ L+ ++A+L+ ++
Sbjct: 1094 ASITALEAKIAQLEEQL 1110
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 64.5 bits (150), Expect = 2e-09
Identities = 86/371 (23%), Positives = 149/371 (40%), Gaps = 29/371 (7%)
Query: 496 QVDRAEGEEETFALDR-EVQA-LRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG 553
Q++ + E T A + ++QA + + Q+ A L E E + +S + L+
Sbjct: 420 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQS 479
Query: 554 TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV 613
+ S Q EEL + Q I + + E L++Q +
Sbjct: 480 SISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEK-- 537
Query: 614 AHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
Q +L ++ +A+ + LR +V +LS S ++ Q+ K+ A + +
Sbjct: 538 ---QAQLAQTLQQQEQAS---QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQL 591
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVM---ELETQVQVSTN 730
AT A E R A + + D L E E +L+ L+ ++ E Q S
Sbjct: 592 AT------AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVT 645
Query: 731 QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
Q +R+ E E L A ++ R Q E Q + A+LE + + E +A + +
Sbjct: 646 QAQREKAELSRKVEELQACVETARQ---EQHEAQAQVAELELQLRSEQQKAT-----EKE 697
Query: 791 RIAELETEVSEY--KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKS 848
R+A+ + ++ E LK + T+G L +D + E Q ++ELKAE L
Sbjct: 698 RVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK 757
Query: 849 RALGHTELSRA 859
R E RA
Sbjct: 758 RERKELEEERA 768
Score = 50.4 bits (115), Expect = 3e-05
Identities = 64/228 (28%), Positives = 106/228 (46%), Gaps = 24/228 (10%)
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
EL ++ EA L++LRQ V +L E + +EH A + QS T K
Sbjct: 1071 ELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEH---ASGSGAQSEAAGRTEPTGPK 1127
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
L E A++ KL+++ + + L+ R E ++ ++ QL + +E
Sbjct: 1128 L----EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQE 1183
Query: 739 ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQR----IAE 794
+ L A+ QRE A F+ K D SKA+ E R ++A+R I+
Sbjct: 1184 LGHSQSAL-ASAQRELA------AFRTKVQD-HSKAEDEWKAQVARGRQEAERKNSLISS 1235
Query: 795 LETEVSEYKLKNEVMATEG---ELRNNNMDDSDRVRELQEQVAELKAE 839
LE EVS L +V+ EG EL+ M +S++ ++L+E++ L+AE
Sbjct: 1236 LEEEVS--ILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAE 1281
Score = 42.3 bits (95), Expect = 0.007
Identities = 80/357 (22%), Positives = 144/357 (40%), Gaps = 22/357 (6%)
Query: 500 AEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASG 559
A EE A RE A + +++ A L EI ++ +A N +R S+ A
Sbjct: 592 ATAAEEREASLRERDAALKQLEALEKEKAAKL-EILQQQLQVA-NEARDSAQTSVTQAQR 649
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENEN-KSLRRQRVDNNVAHLQD 618
+K EL+R ++ +L +E K+ ++RV LQ+
Sbjct: 650 EK-AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQE 708
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
+L A+K SL++ ++R ++ E QR + E K E ++V K+
Sbjct: 709 QLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAET------RSLVEQHKRERKE 762
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALT-ELKELRLKVMELETQVQVSTNQL---RR 734
L GR +L ++L E E L EL E E++ + ++ R
Sbjct: 763 LEEERAGRKGLEARL-QQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRE 821
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADL-ESKAKYESMQANIRNMEDAQRIA 793
+ E+++ A Q + L T + E + +L E+K K ++++ Q+
Sbjct: 822 RYEDSQQEEAQYGAMFQEQ--LMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNE 879
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
E + + +V E E+R + +D + LQE++A E+ RLE +A
Sbjct: 880 LAELHANLARALQQVQ--EKEVRAQKL--ADDLSTLQEKMAATSKEVARLETLVRKA 932
Score = 37.1 bits (82), Expect = 0.28
Identities = 74/420 (17%), Positives = 159/420 (37%), Gaps = 30/420 (7%)
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
+ Q D+A+ + R E + Q + + EG+++ A R ++A
Sbjct: 1021 RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 1080
Query: 516 LRRANVD-MQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXX 574
+ ++ ++Q + +++ E A + QS G +G K E L +
Sbjct: 1081 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRA--EVSKL 1138
Query: 575 XXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSL 634
+ + + + + EL + A A L
Sbjct: 1139 EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQREL 1198
Query: 635 KDLRQRV---SELSESWQRHLQEHKQEAPAA-PVQSNVVSDIMATPKKLLRAWEGRSADM 690
R +V S+ + W+ + +QEA + S++ ++ +++L EG S ++
Sbjct: 1199 AAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEK-EGESKEL 1257
Query: 691 LKL------DEELMTTRIREVEALTELKELRL--KVMELETQVQVSTNQLRRQDEEARLL 742
+L + + R+R ++A T R + L +VQ + +Q + L
Sbjct: 1258 KRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENL 1317
Query: 743 RENLDAALQRERALQTRQREFQHKYADLES-----KAKYESMQANIRNMEDAQRIA---E 794
R+ L + +R L + +Q K+ E + ++ S QA + + A+ + +
Sbjct: 1318 RQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQ 1377
Query: 795 LETEVSEYKLKNEVMATE---GELRNNNMDDSDRVRE---LQEQVAELKAEIMRLEAWKS 848
E +E + + E+ ++ G LR + + E L+++VAE + +L A K+
Sbjct: 1378 AEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKA 1437
Score = 36.7 bits (81), Expect = 0.36
Identities = 90/360 (25%), Positives = 144/360 (40%), Gaps = 50/360 (13%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAEN--NSRQSSLEGTESASG- 559
E E L +EV A R D QQ A + MT+ E +RQ E E +G
Sbjct: 806 ESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGI 865
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDE 619
+ H EL Q + + K +R Q++ ++++ LQ++
Sbjct: 866 ESHSELQISRQQNELAELHANLARALQ-----------QVQEKEVRAQKLADDLSTLQEK 914
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
+ A A L+ L ++ E E+ R L K+ A A Q +
Sbjct: 915 MAATSKEVAR----LETLVRKAGEQQETASRELV--KEPARAGDRQP-----------EW 957
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEAL-TELKELRLKVMELETQVQVSTNQLRRQDEE 738
L +GR + + M RE E + EL+ LR +ME + Q Q Q R E
Sbjct: 958 LEEQQGRQFCSTQAALQAME---REAEQMGNELERLRAALMESQGQQQEERGQQER--EV 1012
Query: 739 ARLLRE--NLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
ARL +E A L E+A + + E + + A E + ++ ++Q + A + E E
Sbjct: 1013 ARLTQERGRAQADLALEKAARA-ELEMRLQNALNEQRVEFATLQEAL-----AHALTEKE 1066
Query: 797 TEVSEY-KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
+ E KL+ A EL + V++L+EQ+A+ + E +S A G TE
Sbjct: 1067 GKDQELAKLRGLEAAQIKELE----ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTE 1122
Score = 36.3 bits (80), Expect = 0.48
Identities = 43/229 (18%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK-KLLRAWEG 685
E E + + + Q ++ + + L E ++EA + + V++ K K+L +
Sbjct: 1472 EVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQR 1531
Query: 686 RSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR---QDEEARLL 742
+ KL ++ + + E +++EL K+ + + +V +L+ Q E++
Sbjct: 1532 FQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQE 1591
Query: 743 RENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY 802
+ L A L +A +++ + Y KAK +N E +++ LE +
Sbjct: 1592 AQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLE----QL 1647
Query: 803 KLKNEVMATEGELRNNNMDDSD-RVRELQEQVAELKAEIMRLEAWKSRA 850
+ +N+ + E E + + + + +E ++ L A++ LEA + A
Sbjct: 1648 QKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHA 1696
Score = 33.9 bits (74), Expect = 2.6
Identities = 64/369 (17%), Positives = 143/369 (38%), Gaps = 15/369 (4%)
Query: 498 DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAEN-NSRQSSLEGTES 556
++ E + + L+ ++++ ++ + ++R+A D+++ + E+ + SLE +
Sbjct: 671 EQHEAQAQVAELELQLRSEQQKATE-KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKR 729
Query: 557 ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH- 615
+ EE RC+ ++E K L + AH
Sbjct: 730 RAADALEEQQRCISELKAETRSLVEQHKRERKE----LEEERAGRKGLEARLQQLGEAHQ 785
Query: 616 LQDELIAVKLREAEA--NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
+ E++ +L EA A + + + Q V E++ +W+ ++ +QE A + +M
Sbjct: 786 AETEVLRRELAEAMAAQHTAESECEQLVKEVA-AWRERYEDSQQEE--AQYGAMFQEQLM 842
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
++ +A + K+ + ++ EL EL + QVQ + +
Sbjct: 843 TLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQ 902
Query: 734 RQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN---MEDAQ 790
+ ++ L+E + A + L+T R+ + + E +A R +E+ Q
Sbjct: 903 KLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQ 962
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
T+ + ++ E EL + + QE+ + + E+ RL + RA
Sbjct: 963 GRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRA 1022
Query: 851 LGHTELSRA 859
L +A
Sbjct: 1023 QADLALEKA 1031
>D11393-1|BAA01989.1| 208|Homo sapiens human non-muscle myosin
heavy chain protein.
Length = 208
Score = 62.1 bits (144), Expect = 8e-09
Identities = 48/160 (30%), Positives = 84/160 (52%), Gaps = 9/160 (5%)
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERAL- 756
M I+E+E E +E + ++LE +V+T ++ EE +++ E+ + L +E+ L
Sbjct: 1 MQQNIQELEEQLEEEESARQKLQLE---KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLL 57
Query: 757 QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGEL 815
+ R EF + E K+K A ++N +A I +LE + E K + E+ T +L
Sbjct: 58 EDRIAEFTTNLTEEEEKSK---SLAKLKNKHEAM-ITDLEERLRREEKQRQELEKTRRKL 113
Query: 816 RNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
++ D SD++ ELQ Q+AELK ++ + E AL E
Sbjct: 114 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVE 153
Score = 36.3 bits (80), Expect = 0.48
Identities = 52/215 (24%), Positives = 105/215 (48%), Gaps = 22/215 (10%)
Query: 594 IDELENENKSLRRQRV--DNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++E E+ + L+ ++V + + L++E I ++ + + K L R++E + +
Sbjct: 12 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 71
Query: 652 LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTEL 711
++ K A +++D+ ++ LR E K +EL TR R++E +
Sbjct: 72 EEKSKSLAKLKNKHEAMITDL----EERLRREE-------KQRQELEKTR-RKLEG--DS 117
Query: 712 KELRLKVMELETQVQVSTNQLRRQDEE--ARLLRENLDAALQRERALQTRQREFQHKYAD 769
+L ++ EL+ Q+ QL +++EE A L R +AA Q+ AL+ + RE + + ++
Sbjct: 118 TDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA-QKNMALK-KIRELESQISE 175
Query: 770 LESKAKYESMQANIRNMEDAQRIAELETEVSEYKL 804
L+ ES +A+ E +R E EV + +L
Sbjct: 176 LQE--DLESERASRNKAEKQKRDLGEELEVLKTEL 208
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 60.9 bits (141), Expect = 2e-08
Identities = 57/261 (21%), Positives = 122/261 (46%), Gaps = 14/261 (5%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + +DEL K R+ +A LK+L Q+ S+L+E + LQE Q
Sbjct: 845 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETELY 903
Query: 664 VQSNVVSDIMATPKK----LLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL----R 715
++ + +A K+ +L E R + ++L R + + + +L+E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
+L+ + + ++++ ++E ++ + + + + L+ R + A+ E KAK
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 776 YESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ ++N ++ I+ELE + E K + E+ + +L + D +++ +LQ Q+A
Sbjct: 1024 NLT---KLKNKHESM-ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 835 ELKAEIMRLEAWKSRALGHTE 855
ELK ++ + E AL +
Sbjct: 1080 ELKMQLAKKEEELQAALARLD 1100
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 1604
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1724
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 1725 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 1777
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 1778 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 1811
Score = 45.6 bits (103), Expect = 8e-04
Identities = 98/480 (20%), Positives = 196/480 (40%), Gaps = 48/480 (10%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSV--KVNP-KKMKKLEKEYTVIKTKEQGDIA 462
D+++ + ++ +L K E QAA L + K N KK+++LE + ++ + A
Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1132
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETF----ALDRE------ 512
++ R L + + Q RA+ E+E ALD E
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1192
Query: 513 -VQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESASGQKHEELA- 566
VQ +R+ + + L L++ + + + +N + L G GQ +E+
Sbjct: 1193 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 567 --RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RRQRVDNNVA- 614
+ L+ + +L+NE +S+ + ++ +VA
Sbjct: 1253 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1312
Query: 615 ---HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
LQD EL+ + R+ + N+S K LRQ + E S Q L E + + +
Sbjct: 1313 LSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQV 725
+ ++ KK L+ + A ++ EE +E+E LT+ E + K+ + + ++
Sbjct: 1370 NIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 726 QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN 785
Q + L + R L NL+ ++ L ++ KYAD +A+ E+ + +
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAELKAEIMRLE 844
+ A+ + E E + N+++ E E ++ DD V EL++ L+ ++ ++
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/258 (18%), Positives = 111/258 (43%), Gaps = 15/258 (5%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+E + L + + + L+DE++ + + + + K L +R+S+L+ + ++
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K +++S++ KK E +S L E+L R++E + +
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKK-----EEKSRQEL---EKLK----RKLEG--DASDF 1067
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
++ +L+ Q+ QL +++EE + LD + ++ + RE + +DL+
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQV 833
E N + ELE +E + + AT+ ELR + +++ L E+
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1187
Query: 834 AELKAEIMRLEAWKSRAL 851
+A++ + ++A+
Sbjct: 1188 RSHEAQVQEMRQKHAQAV 1205
Score = 41.5 bits (93), Expect = 0.013
Identities = 59/264 (22%), Positives = 117/264 (44%), Gaps = 19/264 (7%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
ENE K+ + ++ ++ LQ++L A + +A+L ++L + ++ S S + LQ+ K+
Sbjct: 1677 ENEKKA---KSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS-SLSGRNALQDEKR 1732
Query: 658 EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLK 717
A Q + + + + + A R + E+L E + + R
Sbjct: 1733 RLEARIAQ---LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-- 1787
Query: 718 VMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ--REFQHKYADLES-KA 774
+LE Q + ++L + + ++ AAL+ + A Q +E + K A +S K
Sbjct: 1788 -QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEY------KLKNEVMATEGELRNNNMDDSDRVRE 828
K + ++ + +ED +++AE E +E +LK ++ E E + N + RE
Sbjct: 1847 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Query: 829 LQEQVAELKAEIMRLEAWKSRALG 852
L E +A + A KS+ G
Sbjct: 1907 LDEATESNEAMGREVNALKSKLRG 1930
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 60.9 bits (141), Expect = 2e-08
Identities = 57/261 (21%), Positives = 122/261 (46%), Gaps = 14/261 (5%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + +DEL K R+ +A LK+L Q+ S+L+E + LQE Q
Sbjct: 845 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETELY 903
Query: 664 VQSNVVSDIMATPKK----LLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL----R 715
++ + +A K+ +L E R + ++L R + + + +L+E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
+L+ + + ++++ ++E ++ + + + + L+ R + A+ E KAK
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 776 YESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ ++N ++ I+ELE + E K + E+ + +L + D +++ +LQ Q+A
Sbjct: 1024 NLT---KLKNKHESM-ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 835 ELKAEIMRLEAWKSRALGHTE 855
ELK ++ + E AL +
Sbjct: 1080 ELKMQLAKKEEELQAALARLD 1100
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 1604
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1724
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 1725 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 1777
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 1778 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 1811
Score = 45.6 bits (103), Expect = 8e-04
Identities = 98/480 (20%), Positives = 196/480 (40%), Gaps = 48/480 (10%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSV--KVNP-KKMKKLEKEYTVIKTKEQGDIA 462
D+++ + ++ +L K E QAA L + K N KK+++LE + ++ + A
Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1132
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETF----ALDRE------ 512
++ R L + + Q RA+ E+E ALD E
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1192
Query: 513 -VQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESASGQKHEELA- 566
VQ +R+ + + L L++ + + + +N + L G GQ +E+
Sbjct: 1193 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 567 --RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RRQRVDNNVA- 614
+ L+ + +L+NE +S+ + ++ +VA
Sbjct: 1253 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1312
Query: 615 ---HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
LQD EL+ + R+ + N+S K LRQ + E S Q L E + + +
Sbjct: 1313 LSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQV 725
+ ++ KK L+ + A ++ EE +E+E LT+ E + K+ + + ++
Sbjct: 1370 NIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 726 QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN 785
Q + L + R L NL+ ++ L ++ KYAD +A+ E+ + +
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAELKAEIMRLE 844
+ A+ + E E + N+++ E E ++ DD V EL++ L+ ++ ++
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/258 (18%), Positives = 111/258 (43%), Gaps = 15/258 (5%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+E + L + + + L+DE++ + + + + K L +R+S+L+ + ++
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K +++S++ KK E +S L E+L R++E + +
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKK-----EEKSRQEL---EKLK----RKLEG--DASDF 1067
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
++ +L+ Q+ QL +++EE + LD + ++ + RE + +DL+
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQV 833
E N + ELE +E + + AT+ ELR + +++ L E+
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1187
Query: 834 AELKAEIMRLEAWKSRAL 851
+A++ + ++A+
Sbjct: 1188 RSHEAQVQEMRQKHAQAV 1205
Score = 41.5 bits (93), Expect = 0.013
Identities = 59/264 (22%), Positives = 117/264 (44%), Gaps = 19/264 (7%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
ENE K+ + ++ ++ LQ++L A + +A+L ++L + ++ S S + LQ+ K+
Sbjct: 1677 ENEKKA---KSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS-SLSGRNALQDEKR 1732
Query: 658 EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLK 717
A Q + + + + + A R + E+L E + + R
Sbjct: 1733 RLEARIAQ---LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-- 1787
Query: 718 VMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ--REFQHKYADLES-KA 774
+LE Q + ++L + + ++ AAL+ + A Q +E + K A +S K
Sbjct: 1788 -QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEY------KLKNEVMATEGELRNNNMDDSDRVRE 828
K + ++ + +ED +++AE E +E +LK ++ E E + N + RE
Sbjct: 1847 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Query: 829 LQEQVAELKAEIMRLEAWKSRALG 852
L E +A + A KS+ G
Sbjct: 1907 LDEATESNEAMGREVNALKSKLRG 1930
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 60.9 bits (141), Expect = 2e-08
Identities = 57/261 (21%), Positives = 122/261 (46%), Gaps = 14/261 (5%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + +DEL K R+ +A LK+L Q+ S+L+E + LQE Q
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETELY 910
Query: 664 VQSNVVSDIMATPKK----LLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL----R 715
++ + +A K+ +L E R + ++L R + + + +L+E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
+L+ + + ++++ ++E ++ + + + + L+ R + A+ E KAK
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 776 YESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ ++N ++ I+ELE + E K + E+ + +L + D +++ +LQ Q+A
Sbjct: 1031 NLT---KLKNKHESM-ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 835 ELKAEIMRLEAWKSRALGHTE 855
ELK ++ + E AL +
Sbjct: 1087 ELKMQLAKKEEELQAALARLD 1107
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 1611
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 1672 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1731
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 1732 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 1784
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 1785 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 1818
Score = 45.6 bits (103), Expect = 8e-04
Identities = 98/480 (20%), Positives = 196/480 (40%), Gaps = 48/480 (10%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSV--KVNP-KKMKKLEKEYTVIKTKEQGDIA 462
D+++ + ++ +L K E QAA L + K N KK+++LE + ++ + A
Sbjct: 1080 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1139
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETF----ALDRE------ 512
++ R L + + Q RA+ E+E ALD E
Sbjct: 1140 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1199
Query: 513 -VQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESASGQKHEELA- 566
VQ +R+ + + L L++ + + + +N + L G GQ +E+
Sbjct: 1200 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1259
Query: 567 --RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RRQRVDNNVA- 614
+ L+ + +L+NE +S+ + ++ +VA
Sbjct: 1260 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1319
Query: 615 ---HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
LQD EL+ + R+ + N+S K LRQ + E S Q L E + + +
Sbjct: 1320 LSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQV 725
+ ++ KK L+ + A ++ EE +E+E LT+ E + K+ + + ++
Sbjct: 1377 NIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 726 QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN 785
Q + L + R L NL+ ++ L ++ KYAD +A+ E+ + +
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAELKAEIMRLE 844
+ A+ + E E + N+++ E E ++ DD V EL++ L+ ++ ++
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/258 (18%), Positives = 111/258 (43%), Gaps = 15/258 (5%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+E + L + + + L+DE++ + + + + K L +R+S+L+ + ++
Sbjct: 969 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K +++S++ KK E +S L E+L R++E + +
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKK-----EEKSRQEL---EKLK----RKLEG--DASDF 1074
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
++ +L+ Q+ QL +++EE + LD + ++ + RE + +DL+
Sbjct: 1075 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQV 833
E N + ELE +E + + AT+ ELR + +++ L E+
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1194
Query: 834 AELKAEIMRLEAWKSRAL 851
+A++ + ++A+
Sbjct: 1195 RSHEAQVQEMRQKHAQAV 1212
Score = 41.5 bits (93), Expect = 0.013
Identities = 59/264 (22%), Positives = 117/264 (44%), Gaps = 19/264 (7%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
ENE K+ + ++ ++ LQ++L A + +A+L ++L + ++ S S + LQ+ K+
Sbjct: 1684 ENEKKA---KSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS-SLSGRNALQDEKR 1739
Query: 658 EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLK 717
A Q + + + + + A R + E+L E + + R
Sbjct: 1740 RLEARIAQ---LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-- 1794
Query: 718 VMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ--REFQHKYADLES-KA 774
+LE Q + ++L + + ++ AAL+ + A Q +E + K A +S K
Sbjct: 1795 -QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEY------KLKNEVMATEGELRNNNMDDSDRVRE 828
K + ++ + +ED +++AE E +E +LK ++ E E + N + RE
Sbjct: 1854 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Query: 829 LQEQVAELKAEIMRLEAWKSRALG 852
L E +A + A KS+ G
Sbjct: 1914 LDEATESNEAMGREVNALKSKLRG 1937
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 60.9 bits (141), Expect = 2e-08
Identities = 57/261 (21%), Positives = 122/261 (46%), Gaps = 14/261 (5%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + +DEL K R+ +A LK+L Q+ S+L+E + LQE Q
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETELY 910
Query: 664 VQSNVVSDIMATPKK----LLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL----R 715
++ + +A K+ +L E R + ++L R + + + +L+E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
+L+ + + ++++ ++E ++ + + + + L+ R + A+ E KAK
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 776 YESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ ++N ++ I+ELE + E K + E+ + +L + D +++ +LQ Q+A
Sbjct: 1031 NLT---KLKNKHESM-ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 835 ELKAEIMRLEAWKSRALGHTE 855
ELK ++ + E AL +
Sbjct: 1087 ELKMQLAKKEEELQAALARLD 1107
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 1611
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 1672 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1731
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 1732 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 1784
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 1785 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 1818
Score = 45.6 bits (103), Expect = 8e-04
Identities = 98/480 (20%), Positives = 196/480 (40%), Gaps = 48/480 (10%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSV--KVNP-KKMKKLEKEYTVIKTKEQGDIA 462
D+++ + ++ +L K E QAA L + K N KK+++LE + ++ + A
Sbjct: 1080 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1139
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETF----ALDRE------ 512
++ R L + + Q RA+ E+E ALD E
Sbjct: 1140 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1199
Query: 513 -VQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESASGQKHEELA- 566
VQ +R+ + + L L++ + + + +N + L G GQ +E+
Sbjct: 1200 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1259
Query: 567 --RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RRQRVDNNVA- 614
+ L+ + +L+NE +S+ + ++ +VA
Sbjct: 1260 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1319
Query: 615 ---HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
LQD EL+ + R+ + N+S K LRQ + E S Q L E + + +
Sbjct: 1320 LSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQV 725
+ ++ KK L+ + A ++ EE +E+E LT+ E + K+ + + ++
Sbjct: 1377 NIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 726 QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN 785
Q + L + R L NL+ ++ L ++ KYAD +A+ E+ + +
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAELKAEIMRLE 844
+ A+ + E E + N+++ E E ++ DD V EL++ L+ ++ ++
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/258 (18%), Positives = 111/258 (43%), Gaps = 15/258 (5%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+E + L + + + L+DE++ + + + + K L +R+S+L+ + ++
Sbjct: 969 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K +++S++ KK E +S L E+L R++E + +
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKK-----EEKSRQEL---EKLK----RKLEG--DASDF 1074
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
++ +L+ Q+ QL +++EE + LD + ++ + RE + +DL+
Sbjct: 1075 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQV 833
E N + ELE +E + + AT+ ELR + +++ L E+
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1194
Query: 834 AELKAEIMRLEAWKSRAL 851
+A++ + ++A+
Sbjct: 1195 RSHEAQVQEMRQKHAQAV 1212
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 60.9 bits (141), Expect = 2e-08
Identities = 57/261 (21%), Positives = 122/261 (46%), Gaps = 14/261 (5%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + +DEL K R+ +A LK+L Q+ S+L+E + LQE Q
Sbjct: 730 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETELY 788
Query: 664 VQSNVVSDIMATPKK----LLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL----R 715
++ + +A K+ +L E R + ++L R + + + +L+E
Sbjct: 789 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 848
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
+L+ + + ++++ ++E ++ + + + + L+ R + A+ E KAK
Sbjct: 849 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 908
Query: 776 YESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ ++N ++ I+ELE + E K + E+ + +L + D +++ +LQ Q+A
Sbjct: 909 NLT---KLKNKHESM-ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 964
Query: 835 ELKAEIMRLEAWKSRALGHTE 855
ELK ++ + E AL +
Sbjct: 965 ELKMQLAKKEEELQAALARLD 985
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 1433 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 1489
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 1490 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1549
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 1550 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1609
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 1610 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 1662
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 1663 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 1696
Score = 45.6 bits (103), Expect = 8e-04
Identities = 98/480 (20%), Positives = 196/480 (40%), Gaps = 48/480 (10%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSV--KVNP-KKMKKLEKEYTVIKTKEQGDIA 462
D+++ + ++ +L K E QAA L + K N KK+++LE + ++ + A
Sbjct: 958 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1017
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETF----ALDRE------ 512
++ R L + + Q RA+ E+E ALD E
Sbjct: 1018 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1077
Query: 513 -VQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESASGQKHEELA- 566
VQ +R+ + + L L++ + + + +N + L G GQ +E+
Sbjct: 1078 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1137
Query: 567 --RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RRQRVDNNVA- 614
+ L+ + +L+NE +S+ + ++ +VA
Sbjct: 1138 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1197
Query: 615 ---HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
LQD EL+ + R+ + N+S K LRQ + E S Q L E + + +
Sbjct: 1198 LSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQNLERHISTL 1254
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQV 725
+ ++ KK L+ + A ++ EE +E+E LT+ E + K+ + + ++
Sbjct: 1255 NIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1310
Query: 726 QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN 785
Q + L + R L NL+ ++ L ++ KYAD +A+ E+ + +
Sbjct: 1311 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1370
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAELKAEIMRLE 844
+ A+ + E E + N+++ E E ++ DD V EL++ L+ ++ ++
Sbjct: 1371 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1430
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/258 (18%), Positives = 111/258 (43%), Gaps = 15/258 (5%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+E + L + + + L+DE++ + + + + K L +R+S+L+ + ++
Sbjct: 847 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 906
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K +++S++ KK E +S L E+L R++E + +
Sbjct: 907 AKNLTKLKNKHESMISELEVRLKK-----EEKSRQEL---EKLK----RKLEG--DASDF 952
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
++ +L+ Q+ QL +++EE + LD + ++ + RE + +DL+
Sbjct: 953 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1012
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQV 833
E N + ELE +E + + AT+ ELR + +++ L E+
Sbjct: 1013 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1072
Query: 834 AELKAEIMRLEAWKSRAL 851
+A++ + ++A+
Sbjct: 1073 RSHEAQVQEMRQKHAQAV 1090
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 60.9 bits (141), Expect = 2e-08
Identities = 57/261 (21%), Positives = 122/261 (46%), Gaps = 14/261 (5%)
Query: 604 LRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAP 663
L+ R + + +DEL K R+ +A LK+L Q+ S+L+E + LQE Q
Sbjct: 857 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-KNLLQEQLQAETELY 915
Query: 664 VQSNVVSDIMATPKK----LLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL----R 715
++ + +A K+ +L E R + ++L R + + + +L+E
Sbjct: 916 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 975
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
+L+ + + ++++ ++E ++ + + + + L+ R + A+ E KAK
Sbjct: 976 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1035
Query: 776 YESMQANIRNMEDAQRIAELETEVS-EYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ ++N ++ I+ELE + E K + E+ + +L + D +++ +LQ Q+A
Sbjct: 1036 NLT---KLKNKHESM-ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1091
Query: 835 ELKAEIMRLEAWKSRALGHTE 855
ELK ++ + E AL +
Sbjct: 1092 ELKMQLAKKEEELQAALARLD 1112
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 1560 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 1616
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 1617 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1676
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 1677 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1736
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 1737 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 1789
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 1790 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 1823
Score = 45.6 bits (103), Expect = 8e-04
Identities = 98/480 (20%), Positives = 196/480 (40%), Gaps = 48/480 (10%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSV--KVNP-KKMKKLEKEYTVIKTKEQGDIA 462
D+++ + ++ +L K E QAA L + K N KK+++LE + ++ + A
Sbjct: 1085 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1144
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETF----ALDRE------ 512
++ R L + + Q RA+ E+E ALD E
Sbjct: 1145 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1204
Query: 513 -VQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESASGQKHEELA- 566
VQ +R+ + + L L++ + + + +N + L G GQ +E+
Sbjct: 1205 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1264
Query: 567 --RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RRQRVDNNVA- 614
+ L+ + +L+NE +S+ + ++ +VA
Sbjct: 1265 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1324
Query: 615 ---HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
LQD EL+ + R+ + N+S K LRQ + E S Q L E + + +
Sbjct: 1325 LSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQNLERHISTL 1381
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQV 725
+ ++ KK L+ + A ++ EE +E+E LT+ E + K+ + + ++
Sbjct: 1382 NIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1437
Query: 726 QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN 785
Q + L + R L NL+ ++ L ++ KYAD +A+ E+ + +
Sbjct: 1438 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1497
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAELKAEIMRLE 844
+ A+ + E E + N+++ E E ++ DD V EL++ L+ ++ ++
Sbjct: 1498 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1557
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/258 (18%), Positives = 111/258 (43%), Gaps = 15/258 (5%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+E + L + + + L+DE++ + + + + K L +R+S+L+ + ++
Sbjct: 974 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1033
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K +++S++ KK E +S L E+L R++E + +
Sbjct: 1034 AKNLTKLKNKHESMISELEVRLKK-----EEKSRQEL---EKLK----RKLEG--DASDF 1079
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
++ +L+ Q+ QL +++EE + LD + ++ + RE + +DL+
Sbjct: 1080 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1139
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQV 833
E N + ELE +E + + AT+ ELR + +++ L E+
Sbjct: 1140 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1199
Query: 834 AELKAEIMRLEAWKSRAL 851
+A++ + ++A+
Sbjct: 1200 RSHEAQVQEMRQKHAQAV 1217
>AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1
variant protein.
Length = 459
Score = 60.5 bits (140), Expect = 3e-08
Identities = 54/198 (27%), Positives = 97/198 (48%), Gaps = 10/198 (5%)
Query: 665 QSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQ 724
+S + +D A+P L+ EG A + L+E+L T R++ E +LKEL ++LE
Sbjct: 27 RSGLCTDREASP---LQEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLE-- 81
Query: 725 VQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR--EFQHKYADLESKAKYESMQAN 782
QV + + Q+++A L R +A + + AL+ ++R E AD A + A
Sbjct: 82 -QVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAE 140
Query: 783 IRNMEDAQRIAELETEVSEYKLKNEVMATEGELR-NNNMDDSDRVRELQEQVAELKAEIM 841
R Q + L+ V E E++ E E + ++ S ++++L+EQ A LK ++
Sbjct: 141 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALV 200
Query: 842 RL-EAWKSRALGHTELSR 858
R+ + S H +L +
Sbjct: 201 RMRDLSSSEKQEHVKLQK 218
Score = 53.6 bits (123), Expect = 3e-06
Identities = 61/249 (24%), Positives = 116/249 (46%), Gaps = 29/249 (11%)
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELS--ESWQRHLQEHKQEAPAAPVQSNVVS 670
V L+++L ++L+ AE LK+L + +L + W+ +QE + + ++ +
Sbjct: 49 VRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEA 108
Query: 671 DIMATPKKLLRAWEGRSAD---MLKLDEELMTTRI----REVEAL--------TELKELR 715
K+ +AD M LD+E+ R +EVEAL T+L+ L+
Sbjct: 109 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 168
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ E + S+ QL++ +E+ L++ AL R R L + +++ K L K
Sbjct: 169 AEIEEKGSDGAASSYQLKQLEEQNARLKD----ALVRMRDLSSSEKQEHVKLQKLMEKKN 224
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGE------LRNNNMDDSDRVREL 829
E + + +++ E+ + E LK +V A G L + N++ ++VREL
Sbjct: 225 QELEVVRQQRERLQEELSQAESTIDE--LKEQVDAALGAEEMVEMLTDRNLNLEEKVREL 282
Query: 830 QEQVAELKA 838
+E V +L+A
Sbjct: 283 RETVGDLEA 291
Score = 43.6 bits (98), Expect = 0.003
Identities = 64/278 (23%), Positives = 121/278 (43%), Gaps = 19/278 (6%)
Query: 516 LRRANVDMQQRLAVALDEIR-SLEMTIAENNSRQSSLEGTESASGQKH--EELARCLQXX 572
++ D+Q+RL A E + +LE + + E A+ K EE A LQ
Sbjct: 90 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 149
Query: 573 XXXXXXXXXXXXXXXXXXXXXIDELENEN--KSLRRQRVDNNVAHLQDELIAVKLREAEA 630
I+E ++ S + ++++ A L+D L V++R+ +
Sbjct: 150 VEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL--VRMRDLSS 207
Query: 631 NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADM 690
S K ++ +L E + L+ +Q+ + + + K+ + A G + +M
Sbjct: 208 --SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEM 264
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDAA 749
+ E++T R +E +++ELR V +LE +++ ++L+ E L LRE LD A
Sbjct: 265 V----EMLTDRNLNLEE--KVRELRETVGDLEAMNEMN-DELQENARETELELREQLDMA 317
Query: 750 LQRERALQTRQREFQHKYADLESK-AKYESMQANIRNM 786
R R Q R Q AD + KY + A+++++
Sbjct: 318 GARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 355
>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
Length = 1263
Score = 59.3 bits (137), Expect = 6e-08
Identities = 59/232 (25%), Positives = 103/232 (44%), Gaps = 18/232 (7%)
Query: 642 SELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATP-----------KKLLRAWEGRSADM 690
S L S E P+ P Q+ + + I+ TP + EG A +
Sbjct: 150 SSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQV 209
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
L+E+L T R++ E +LKEL ++LE QV + + Q+++A L R +A
Sbjct: 210 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLE---QVQEWKSKMQEQQADLQRRLKEARK 266
Query: 751 QRERALQTRQR--EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEV 808
+ + AL+ ++R E AD A + A R Q + L+ V E E+
Sbjct: 267 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 326
Query: 809 MATEGELR-NNNMDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSR 858
+ E E + ++ S ++++L+EQ A LK ++R+ + S H +L +
Sbjct: 327 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 378
Score = 53.6 bits (123), Expect = 3e-06
Identities = 61/249 (24%), Positives = 116/249 (46%), Gaps = 29/249 (11%)
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELS--ESWQRHLQEHKQEAPAAPVQSNVVS 670
V L+++L ++L+ AE LK+L + +L + W+ +QE + + ++ +
Sbjct: 209 VRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEA 268
Query: 671 DIMATPKKLLRAWEGRSAD---MLKLDEELMTTRI----REVEAL--------TELKELR 715
K+ +AD M LD+E+ R +EVEAL T+L+ L+
Sbjct: 269 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 328
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ E + S+ QL++ +E+ L++ AL R R L + +++ K L K
Sbjct: 329 AEIEEKGSDGAASSYQLKQLEEQNARLKD----ALVRMRDLSSSEKQEHVKLQKLMEKKN 384
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGE------LRNNNMDDSDRVREL 829
E + + +++ E+ + E LK +V A G L + N++ ++VREL
Sbjct: 385 QELEVVRQQRERLQEELSQAESTIDE--LKEQVDAALGAEEMVEMLTDRNLNLEEKVREL 442
Query: 830 QEQVAELKA 838
+E V +L+A
Sbjct: 443 RETVGDLEA 451
Score = 43.6 bits (98), Expect = 0.003
Identities = 64/278 (23%), Positives = 121/278 (43%), Gaps = 19/278 (6%)
Query: 516 LRRANVDMQQRLAVALDEIR-SLEMTIAENNSRQSSLEGTESASGQKH--EELARCLQXX 572
++ D+Q+RL A E + +LE + + E A+ K EE A LQ
Sbjct: 250 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 309
Query: 573 XXXXXXXXXXXXXXXXXXXXXIDELENEN--KSLRRQRVDNNVAHLQDELIAVKLREAEA 630
I+E ++ S + ++++ A L+D L V++R+ +
Sbjct: 310 VEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL--VRMRDLSS 367
Query: 631 NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADM 690
S K ++ +L E + L+ +Q+ + + + K+ + A G + +M
Sbjct: 368 --SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEM 424
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDAA 749
+ E++T R +E +++ELR V +LE +++ ++L+ E L LRE LD A
Sbjct: 425 V----EMLTDRNLNLEE--KVRELRETVGDLEAMNEMN-DELQENARETELELREQLDMA 477
Query: 750 LQRERALQTRQREFQHKYADLESK-AKYESMQANIRNM 786
R R Q R Q AD + KY + A+++++
Sbjct: 478 GARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 515
>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
Length = 1139
Score = 59.3 bits (137), Expect = 6e-08
Identities = 59/232 (25%), Positives = 103/232 (44%), Gaps = 18/232 (7%)
Query: 642 SELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATP-----------KKLLRAWEGRSADM 690
S L S E P+ P Q+ + + I+ TP + EG A +
Sbjct: 31 SSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQV 90
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
L+E+L T R++ E +LKEL ++LE QV + + Q+++A L R +A
Sbjct: 91 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLE---QVQEWKSKMQEQQADLQRRLKEARK 147
Query: 751 QRERALQTRQR--EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEV 808
+ + AL+ ++R E AD A + A R Q + L+ V E E+
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 207
Query: 809 MATEGELR-NNNMDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSR 858
+ E E + ++ S ++++L+EQ A LK ++R+ + S H +L +
Sbjct: 208 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 259
Score = 53.6 bits (123), Expect = 3e-06
Identities = 61/249 (24%), Positives = 116/249 (46%), Gaps = 29/249 (11%)
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELS--ESWQRHLQEHKQEAPAAPVQSNVVS 670
V L+++L ++L+ AE LK+L + +L + W+ +QE + + ++ +
Sbjct: 90 VRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEA 149
Query: 671 DIMATPKKLLRAWEGRSAD---MLKLDEELMTTRI----REVEAL--------TELKELR 715
K+ +AD M LD+E+ R +EVEAL T+L+ L+
Sbjct: 150 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 209
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ E + S+ QL++ +E+ L++ AL R R L + +++ K L K
Sbjct: 210 AEIEEKGSDGAASSYQLKQLEEQNARLKD----ALVRMRDLSSSEKQEHVKLQKLMEKKN 265
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGE------LRNNNMDDSDRVREL 829
E + + +++ E+ + E LK +V A G L + N++ ++VREL
Sbjct: 266 QELEVVRQQRERLQEELSQAESTIDE--LKEQVDAALGAEEMVEMLTDRNLNLEEKVREL 323
Query: 830 QEQVAELKA 838
+E V +L+A
Sbjct: 324 RETVGDLEA 332
Score = 45.6 bits (103), Expect = 8e-04
Identities = 65/278 (23%), Positives = 121/278 (43%), Gaps = 19/278 (6%)
Query: 516 LRRANVDMQQRLAVALDEIR-SLEMTIAENNSRQSSLEGTESASGQKH--EELARCLQXX 572
++ D+Q+RL A E + +LE + + E A+ K EE A LQ
Sbjct: 131 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 190
Query: 573 XXXXXXXXXXXXXXXXXXXXXIDELENEN--KSLRRQRVDNNVAHLQDELIAVKLREAEA 630
I+E ++ S + ++++ A L+D L V++R+ +
Sbjct: 191 VEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL--VRMRDLSS 248
Query: 631 NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADM 690
S K ++ +L E + L+ +Q+ + + + K+ + A G + +M
Sbjct: 249 --SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEM 305
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDAA 749
+ E++T R +E +++ELR V +LE +++ ++L+ E L LRE LD A
Sbjct: 306 V----EMLTDRNLNLEE--KVRELRETVGDLEAMNEMN-DELQENARETELELREQLDMA 358
Query: 750 LQRERALQTRQREFQHKYADLESK-AKYESMQANIRNM 786
R R Q R Q AD + KY + AN++++
Sbjct: 359 GARVREAQKRVEAAQETVADYQQTIKKYRQLTANLQDV 396
>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
Length = 1261
Score = 59.3 bits (137), Expect = 6e-08
Identities = 59/232 (25%), Positives = 103/232 (44%), Gaps = 18/232 (7%)
Query: 642 SELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATP-----------KKLLRAWEGRSADM 690
S L S E P+ P Q+ + + I+ TP + EG A +
Sbjct: 148 SSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQV 207
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
L+E+L T R++ E +LKEL ++LE QV + + Q+++A L R +A
Sbjct: 208 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLE---QVQEWKSKMQEQQADLQRRLKEARK 264
Query: 751 QRERALQTRQR--EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEV 808
+ + AL+ ++R E AD A + A R Q + L+ V E E+
Sbjct: 265 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 324
Query: 809 MATEGELR-NNNMDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSR 858
+ E E + ++ S ++++L+EQ A LK ++R+ + S H +L +
Sbjct: 325 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 376
Score = 53.6 bits (123), Expect = 3e-06
Identities = 61/249 (24%), Positives = 116/249 (46%), Gaps = 29/249 (11%)
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELS--ESWQRHLQEHKQEAPAAPVQSNVVS 670
V L+++L ++L+ AE LK+L + +L + W+ +QE + + ++ +
Sbjct: 207 VRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEA 266
Query: 671 DIMATPKKLLRAWEGRSAD---MLKLDEELMTTRI----REVEAL--------TELKELR 715
K+ +AD M LD+E+ R +EVEAL T+L+ L+
Sbjct: 267 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 326
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ E + S+ QL++ +E+ L++ AL R R L + +++ K L K
Sbjct: 327 AEIEEKGSDGAASSYQLKQLEEQNARLKD----ALVRMRDLSSSEKQEHVKLQKLMEKKN 382
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGE------LRNNNMDDSDRVREL 829
E + + +++ E+ + E LK +V A G L + N++ ++VREL
Sbjct: 383 QELEVVRQQRERLQEELSQAESTIDE--LKEQVDAALGAEEMVEMLTDRNLNLEEKVREL 440
Query: 830 QEQVAELKA 838
+E V +L+A
Sbjct: 441 RETVGDLEA 449
Score = 43.6 bits (98), Expect = 0.003
Identities = 64/278 (23%), Positives = 121/278 (43%), Gaps = 19/278 (6%)
Query: 516 LRRANVDMQQRLAVALDEIR-SLEMTIAENNSRQSSLEGTESASGQKH--EELARCLQXX 572
++ D+Q+RL A E + +LE + + E A+ K EE A LQ
Sbjct: 248 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 307
Query: 573 XXXXXXXXXXXXXXXXXXXXXIDELENEN--KSLRRQRVDNNVAHLQDELIAVKLREAEA 630
I+E ++ S + ++++ A L+D L V++R+ +
Sbjct: 308 VEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL--VRMRDLSS 365
Query: 631 NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADM 690
S K ++ +L E + L+ +Q+ + + + K+ + A G + +M
Sbjct: 366 --SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEM 422
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDAA 749
+ E++T R +E +++ELR V +LE +++ ++L+ E L LRE LD A
Sbjct: 423 V----EMLTDRNLNLEE--KVRELRETVGDLEAMNEMN-DELQENARETELELREQLDMA 475
Query: 750 LQRERALQTRQREFQHKYADLESK-AKYESMQANIRNM 786
R R Q R Q AD + KY + A+++++
Sbjct: 476 GARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 513
>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
protein.
Length = 1144
Score = 59.3 bits (137), Expect = 6e-08
Identities = 59/232 (25%), Positives = 103/232 (44%), Gaps = 18/232 (7%)
Query: 642 SELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATP-----------KKLLRAWEGRSADM 690
S L S E P+ P Q+ + + I+ TP + EG A +
Sbjct: 31 SSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQV 90
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
L+E+L T R++ E +LKEL ++LE QV + + Q+++A L R +A
Sbjct: 91 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLE---QVQEWKSKMQEQQADLQRRLKEARK 147
Query: 751 QRERALQTRQR--EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEV 808
+ + AL+ ++R E AD A + A R Q + L+ V E E+
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 207
Query: 809 MATEGELR-NNNMDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSR 858
+ E E + ++ S ++++L+EQ A LK ++R+ + S H +L +
Sbjct: 208 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 259
Score = 53.6 bits (123), Expect = 3e-06
Identities = 61/249 (24%), Positives = 116/249 (46%), Gaps = 29/249 (11%)
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELS--ESWQRHLQEHKQEAPAAPVQSNVVS 670
V L+++L ++L+ AE LK+L + +L + W+ +QE + + ++ +
Sbjct: 90 VRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEA 149
Query: 671 DIMATPKKLLRAWEGRSAD---MLKLDEELMTTRI----REVEAL--------TELKELR 715
K+ +AD M LD+E+ R +EVEAL T+L+ L+
Sbjct: 150 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 209
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ E + S+ QL++ +E+ L++ AL R R L + +++ K L K
Sbjct: 210 AEIEEKGSDGAASSYQLKQLEEQNARLKD----ALVRMRDLSSSEKQEHVKLQKLMEKKN 265
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGE------LRNNNMDDSDRVREL 829
E + + +++ E+ + E LK +V A G L + N++ ++VREL
Sbjct: 266 QELEVVRQQRERLQEELSQAESTIDE--LKEQVDAALGAEEMVEMLTDRNLNLEEKVREL 323
Query: 830 QEQVAELKA 838
+E V +L+A
Sbjct: 324 RETVGDLEA 332
Score = 43.6 bits (98), Expect = 0.003
Identities = 64/278 (23%), Positives = 121/278 (43%), Gaps = 19/278 (6%)
Query: 516 LRRANVDMQQRLAVALDEIR-SLEMTIAENNSRQSSLEGTESASGQKH--EELARCLQXX 572
++ D+Q+RL A E + +LE + + E A+ K EE A LQ
Sbjct: 131 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 190
Query: 573 XXXXXXXXXXXXXXXXXXXXXIDELENEN--KSLRRQRVDNNVAHLQDELIAVKLREAEA 630
I+E ++ S + ++++ A L+D L V++R+ +
Sbjct: 191 VEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL--VRMRDLSS 248
Query: 631 NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADM 690
S K ++ +L E + L+ +Q+ + + + K+ + A G + +M
Sbjct: 249 --SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEM 305
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDAA 749
+ E++T R +E +++ELR V +LE +++ ++L+ E L LRE LD A
Sbjct: 306 V----EMLTDRNLNLEE--KVRELRETVGDLEAMNEMN-DELQENARETELELREQLDMA 358
Query: 750 LQRERALQTRQREFQHKYADLESK-AKYESMQANIRNM 786
R R Q R Q AD + KY + A+++++
Sbjct: 359 GARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 396
>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
protein.
Length = 1278
Score = 59.3 bits (137), Expect = 6e-08
Identities = 59/232 (25%), Positives = 103/232 (44%), Gaps = 18/232 (7%)
Query: 642 SELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATP-----------KKLLRAWEGRSADM 690
S L S E P+ P Q+ + + I+ TP + EG A +
Sbjct: 165 SSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQV 224
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
L+E+L T R++ E +LKEL ++LE QV + + Q+++A L R +A
Sbjct: 225 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLE---QVQEWKSKMQEQQADLQRRLKEARK 281
Query: 751 QRERALQTRQR--EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEV 808
+ + AL+ ++R E AD A + A R Q + L+ V E E+
Sbjct: 282 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 341
Query: 809 MATEGELR-NNNMDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSR 858
+ E E + ++ S ++++L+EQ A LK ++R+ + S H +L +
Sbjct: 342 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 393
Score = 53.6 bits (123), Expect = 3e-06
Identities = 61/249 (24%), Positives = 116/249 (46%), Gaps = 29/249 (11%)
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELS--ESWQRHLQEHKQEAPAAPVQSNVVS 670
V L+++L ++L+ AE LK+L + +L + W+ +QE + + ++ +
Sbjct: 224 VRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEA 283
Query: 671 DIMATPKKLLRAWEGRSAD---MLKLDEELMTTRI----REVEAL--------TELKELR 715
K+ +AD M LD+E+ R +EVEAL T+L+ L+
Sbjct: 284 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 343
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
++ E + S+ QL++ +E+ L++ AL R R L + +++ K L K
Sbjct: 344 AEIEEKGSDGAASSYQLKQLEEQNARLKD----ALVRMRDLSSSEKQEHVKLQKLMEKKN 399
Query: 776 YESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGE------LRNNNMDDSDRVREL 829
E + + +++ E+ + E LK +V A G L + N++ ++VREL
Sbjct: 400 QELEVVRQQRERLQEELSQAESTIDE--LKEQVDAALGAEEMVEMLTDRNLNLEEKVREL 457
Query: 830 QEQVAELKA 838
+E V +L+A
Sbjct: 458 RETVGDLEA 466
Score = 43.6 bits (98), Expect = 0.003
Identities = 64/278 (23%), Positives = 121/278 (43%), Gaps = 19/278 (6%)
Query: 516 LRRANVDMQQRLAVALDEIR-SLEMTIAENNSRQSSLEGTESASGQKH--EELARCLQXX 572
++ D+Q+RL A E + +LE + + E A+ K EE A LQ
Sbjct: 265 MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQE 324
Query: 573 XXXXXXXXXXXXXXXXXXXXXIDELENEN--KSLRRQRVDNNVAHLQDELIAVKLREAEA 630
I+E ++ S + ++++ A L+D L V++R+ +
Sbjct: 325 VEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL--VRMRDLSS 382
Query: 631 NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADM 690
S K ++ +L E + L+ +Q+ + + + K+ + A G + +M
Sbjct: 383 --SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEM 439
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDAA 749
+ E++T R +E +++ELR V +LE +++ ++L+ E L LRE LD A
Sbjct: 440 V----EMLTDRNLNLEE--KVRELRETVGDLEAMNEMN-DELQENARETELELREQLDMA 492
Query: 750 LQRERALQTRQREFQHKYADLESK-AKYESMQANIRNM 786
R R Q R Q AD + KY + A+++++
Sbjct: 493 GARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 530
>AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein.
Length = 3284
Score = 58.0 bits (134), Expect = 1e-07
Identities = 71/335 (21%), Positives = 135/335 (40%), Gaps = 24/335 (7%)
Query: 522 DMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
D+Q+ L+ ++ S++ +A + L+ S QK E+L+R L
Sbjct: 2607 DLQKTLSEEQEKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLRS 2666
Query: 582 XXXXXXXXXXXXIDELENEN---KSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLR 638
+ ELE+E ++L+ Q + + HLQ E + K E E SL+ R
Sbjct: 2667 MLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALE-ELRASLETQR 2725
Query: 639 QRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELM 698
+ S L + + H+Q A + N+ ++ + + + +L ++L
Sbjct: 2726 AQSSRLCVALK-----HEQTA-----KDNLQKELRIEHSRCEALLAQERSQLSELQKDLA 2775
Query: 699 TTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARL--LRENLDAALQRERAL 756
+ R +E L+ RL +L + Q + Q A L L+E + + L
Sbjct: 2776 AEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKSRVVDLQAML 2835
Query: 757 QTRQREFQHKYADLESKA--------KYESMQANIRNMEDAQRIAELETEVSEYKLKNEV 808
+ Q++ H LE++A + + + ++ D +I +L+ V + + K+EV
Sbjct: 2836 EKVQQQALHSQQQLEAEAQKHCEALRREKERELELQRQRDLHKIKQLQQTVRDLESKDEV 2895
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
+ L + L+EQ EL+A RL
Sbjct: 2896 PGSRLHLGSARRAAGSDADHLREQQRELEAMRQRL 2930
Score = 37.5 bits (83), Expect = 0.21
Identities = 40/205 (19%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
Query: 645 SESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIRE 704
+E + +++H++ +S +++ K EG + L E L E
Sbjct: 1326 NEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVETADLKEVLAGKEDSE 1385
Query: 705 VEALTELKELRLKVMEL---ETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ EL+ LR ++ + + ++ +L + E E +AAL++E T+++
Sbjct: 1386 HRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALRKEVEDLTKEQ 1445
Query: 762 EFQHKYADLESKAKYESMQANIRNMED--AQRIAELETEVSEYKLKNEVMATEGELRNNN 819
K A+ + A M+ +E+ +Q + + L+ +V + + LRN
Sbjct: 1446 SETRKQAEKDRSALLSQMKILESELEEQLSQHRGCAKQAEAVTALEQQVASLDKHLRNQR 1505
Query: 820 MDDSDRVRELQEQVAELKAEIMRLE 844
++ E + + E + EI RLE
Sbjct: 1506 QFMDEQAAEREHEREEFQQEIQRLE 1530
Score = 36.7 bits (81), Expect = 0.36
Identities = 37/178 (20%), Positives = 79/178 (44%), Gaps = 11/178 (6%)
Query: 677 KKLLRAWEGRSADMLK-LDEELMTTRIREVEALT-----ELKELRLKVMELETQVQVSTN 730
K L WE L+ L +EL E+E L EL E R ++ ++ +
Sbjct: 371 KTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAER 430
Query: 731 QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNM--ED 788
LR + + E L LQ E EF+ K ++ E + + E++QA+ ++ +
Sbjct: 431 ALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKAQS 490
Query: 789 AQRIAELETEVSEYKLKNEVMATEGE---LRNNNMDDSDRVRELQEQVAELKAEIMRL 843
+ I L +++ + + ++ E R + ++D +++++ ++ E + E +R+
Sbjct: 491 QEEIRRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRI 548
Score = 35.9 bits (79), Expect = 0.64
Identities = 55/230 (23%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Query: 622 AVKLREAEA-NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLL 680
AV E EA LSL ++ EL+ Q +LQ+ K+ A +++ A LL
Sbjct: 268 AVHGLELEALRLSLSNMHTAQLELT---QANLQKEKETALTE--LREMLNSRRAQELALL 322
Query: 681 RAWEGRSADMLKLDE--ELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
++ + ++L+ E +R + ELKE +L+ E+E Q+ + E
Sbjct: 323 QSRQQHELELLREQHAREKEEVVLRCGQEAAELKE-KLQ-SEMEKNAQIVKTLKEDWESE 380
Query: 739 ARLLRENL--DAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
L ENL + + + + ++ Q +FQ + A E +A+ E + + E A R E
Sbjct: 381 KDLCLENLRKELSAKHQSEMEDLQNQFQKELA--EQRAELEKIFQDKNQAERALRNLESH 438
Query: 797 TEVSEYKLKNEVMATEGE-LRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
+ + KL+ ++ + G L + + +E Q ++ L+A L+A
Sbjct: 439 HQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKA 488
Score = 33.1 bits (72), Expect = 4.5
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAE 794
Q++ AR L + L Q++ T + E +H+ A E A ES Q + A R+AE
Sbjct: 921 QEQHAREL-QLLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALL----AARVAE 975
Query: 795 LETEVSEY--KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALG 852
L+T+ + L+ +++ L + + + +RE Q EL + WK +L
Sbjct: 976 LQTKHAADLGALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLH 1035
Query: 853 HTELSRAI 860
T L++ +
Sbjct: 1036 QTILTQEL 1043
>AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparatus
protein 1 variant protein.
Length = 1585
Score = 57.6 bits (133), Expect = 2e-07
Identities = 60/228 (26%), Positives = 97/228 (42%), Gaps = 19/228 (8%)
Query: 637 LRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEE 696
LR +V +LS S ++ Q+ K+ A + +AT A E R A + + D
Sbjct: 33 LRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLAT------AAEEREASLRERDAA 86
Query: 697 LMTTRIREVEALTELKELRLKVM---ELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
L E E +L+ L+ ++ E Q S Q +R+ E E L A ++
Sbjct: 87 LKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETA 146
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY--KLKNEVMAT 811
R Q E Q + A+LE + + E +A + +R+A+ + ++ E LK + T
Sbjct: 147 RQ---EQHEAQAQVAELELQLRSEQQKAT-----EKERVAQEKDQLQEQLQALKESLKVT 198
Query: 812 EGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSRA 859
+G L +D + E Q ++ELKAE L R E RA
Sbjct: 199 KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERA 246
Score = 50.8 bits (116), Expect = 2e-05
Identities = 65/320 (20%), Positives = 118/320 (36%), Gaps = 22/320 (6%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
Q + + E L R+V+ L+ +Q A ++ LE+ + + + E
Sbjct: 119 QTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVA 178
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
Q E+L + D LE + + + + +
Sbjct: 179 QEKDQLQEQLQALKESLKVTKGSLEEEKRRAA-------DALEEQQRCISELKAETRSLV 231
Query: 616 LQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMAT 675
Q + +L E A K L R+ +L E+ Q + ++E A +
Sbjct: 232 EQHKRERKELEEERA--GRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQ 289
Query: 676 PKKLLRAWEGRSADMLK--------LDEELMTTRIREVEALTELKELRLKVMELETQVQV 727
K + AW R D + E+LMT + +A EL+E + KV +E+ ++
Sbjct: 290 LVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSEL 349
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
Q+ RQ E L NL ALQ+ + + R ++ + L+ K S + + +E
Sbjct: 350 ---QISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKE--VARLE 404
Query: 788 DAQRIAELETEVSEYKLKNE 807
R A + E + +L E
Sbjct: 405 TLVRKAGEQQETASRELVKE 424
Score = 50.4 bits (115), Expect = 3e-05
Identities = 64/228 (28%), Positives = 106/228 (46%), Gaps = 24/228 (10%)
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
EL ++ EA L++LRQ V +L E + +EH A + QS T K
Sbjct: 549 ELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEH---ASGSGAQSEAAGRTEPTGPK 605
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
L E A++ KL+++ + + L+ R E ++ ++ QL + +E
Sbjct: 606 L----EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQE 661
Query: 739 ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQR----IAE 794
+ L A+ QRE A F+ K D SKA+ E R ++A+R I+
Sbjct: 662 LGHSQSAL-ASAQRELA------AFRTKVQD-HSKAEDEWKAQVARGRQEAERKNSLISS 713
Query: 795 LETEVSEYKLKNEVMATEG---ELRNNNMDDSDRVRELQEQVAELKAE 839
LE EVS L +V+ EG EL+ M +S++ ++L+E++ L+AE
Sbjct: 714 LEEEVS--ILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAE 759
Score = 42.3 bits (95), Expect = 0.007
Identities = 80/357 (22%), Positives = 144/357 (40%), Gaps = 22/357 (6%)
Query: 500 AEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASG 559
A EE A RE A + +++ A L EI ++ +A N +R S+ A
Sbjct: 70 ATAAEEREASLRERDAALKQLEALEKEKAAKL-EILQQQLQVA-NEARDSAQTSVTQAQR 127
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENEN-KSLRRQRVDNNVAHLQD 618
+K EL+R ++ +L +E K+ ++RV LQ+
Sbjct: 128 EK-AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQE 186
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
+L A+K SL++ ++R ++ E QR + E K E ++V K+
Sbjct: 187 QLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAET------RSLVEQHKRERKE 240
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEAL-TELKELRLKVMELETQVQVSTNQL---RR 734
L GR +L ++L E E L EL E E++ + ++ R
Sbjct: 241 LEEERAGRKGLEARL-QQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRE 299
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADL-ESKAKYESMQANIRNMEDAQRIA 793
+ E+++ A Q + L T + E + +L E+K K ++++ Q+
Sbjct: 300 RYEDSQQEEAQYGAMFQEQ--LMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNE 357
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
E + + +V E E+R + +D + LQE++A E+ RLE +A
Sbjct: 358 LAELHANLARALQQVQ--EKEVRAQKL--ADDLSTLQEKMAATSKEVARLETLVRKA 410
Score = 37.1 bits (82), Expect = 0.28
Identities = 74/420 (17%), Positives = 159/420 (37%), Gaps = 30/420 (7%)
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
+ Q D+A+ + R E + Q + + EG+++ A R ++A
Sbjct: 499 RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 558
Query: 516 LRRANVD-MQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXX 574
+ ++ ++Q + +++ E A + QS G +G K E L +
Sbjct: 559 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRA--EVSKL 616
Query: 575 XXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSL 634
+ + + + + EL + A A L
Sbjct: 617 EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQREL 676
Query: 635 KDLRQRV---SELSESWQRHLQEHKQEAPAA-PVQSNVVSDIMATPKKLLRAWEGRSADM 690
R +V S+ + W+ + +QEA + S++ ++ +++L EG S ++
Sbjct: 677 AAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEK-EGESKEL 735
Query: 691 LKL------DEELMTTRIREVEALTELKELRL--KVMELETQVQVSTNQLRRQDEEARLL 742
+L + + R+R ++A T R + L +VQ + +Q + L
Sbjct: 736 KRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENL 795
Query: 743 RENLDAALQRERALQTRQREFQHKYADLES-----KAKYESMQANIRNMEDAQRIA---E 794
R+ L + +R L + +Q K+ E + ++ S QA + + A+ + +
Sbjct: 796 RQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQ 855
Query: 795 LETEVSEYKLKNEVMATE---GELRNNNMDDSDRVRE---LQEQVAELKAEIMRLEAWKS 848
E +E + + E+ ++ G LR + + E L+++VAE + +L A K+
Sbjct: 856 AEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKA 915
Score = 36.7 bits (81), Expect = 0.36
Identities = 90/360 (25%), Positives = 144/360 (40%), Gaps = 50/360 (13%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAEN--NSRQSSLEGTESASG- 559
E E L +EV A R D QQ A + MT+ E +RQ E E +G
Sbjct: 284 ESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGI 343
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDE 619
+ H EL Q + + K +R Q++ ++++ LQ++
Sbjct: 344 ESHSELQISRQQNELAELHANLARALQ-----------QVQEKEVRAQKLADDLSTLQEK 392
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
+ A A L+ L ++ E E+ R L K+ A A Q +
Sbjct: 393 MAATSKEVAR----LETLVRKAGEQQETASRELV--KEPARAGDRQP-----------EW 435
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEAL-TELKELRLKVMELETQVQVSTNQLRRQDEE 738
L +GR + + M RE E + EL+ LR +ME + Q Q Q R E
Sbjct: 436 LEEQQGRQFCSTQAALQAME---REAEQMGNELERLRAALMESQGQQQEERGQQER--EV 490
Query: 739 ARLLRE--NLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
ARL +E A L E+A + + E + + A E + ++ ++Q + A + E E
Sbjct: 491 ARLTQERGRAQADLALEKAARA-ELEMRLQNALNEQRVEFATLQEAL-----AHALTEKE 544
Query: 797 TEVSEY-KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
+ E KL+ A EL + V++L+EQ+A+ + E +S A G TE
Sbjct: 545 GKDQELAKLRGLEAAQIKELE----ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTE 600
Score = 35.5 bits (78), Expect = 0.84
Identities = 47/236 (19%), Positives = 104/236 (44%), Gaps = 12/236 (5%)
Query: 630 ANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRA-WEGRSA 688
ANL + L + + E + + L + +A + + A +++ A +EG
Sbjct: 942 ANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV 1001
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR---RQDEEARLLREN 745
+L EE + + +++EL K+ + + +V +L+ Q E++ +
Sbjct: 1002 KVL---EERQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR 1058
Query: 746 LDAALQRERA-LQTRQREFQHKYADLE-SKAKYES-MQANIRNMEDAQRIAELETEVSEY 802
L A L +A L +++ +H +E +K Y++ Q N E + + +L+ E E
Sbjct: 1059 LQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKEL 1118
Query: 803 KLKNEVMATEGELRNNNMDDSDRV-RELQEQVAELKAEIMRLEAWKSRALGHTELS 857
+ + E + E + ++++ R L QV L+A++ + + R LG +++
Sbjct: 1119 RAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ-QLRDLGKFQVA 1173
Score = 33.9 bits (74), Expect = 2.6
Identities = 64/369 (17%), Positives = 143/369 (38%), Gaps = 15/369 (4%)
Query: 498 DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAEN-NSRQSSLEGTES 556
++ E + + L+ ++++ ++ + ++R+A D+++ + E+ + SLE +
Sbjct: 149 EQHEAQAQVAELELQLRSEQQKATE-KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKR 207
Query: 557 ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH- 615
+ EE RC+ ++E K L + AH
Sbjct: 208 RAADALEEQQRCISELKAETRSLVEQHKRERKE----LEEERAGRKGLEARLQQLGEAHQ 263
Query: 616 LQDELIAVKLREAEA--NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
+ E++ +L EA A + + + Q V E++ +W+ ++ +QE A + +M
Sbjct: 264 AETEVLRRELAEAMAAQHTAESECEQLVKEVA-AWRERYEDSQQEE--AQYGAMFQEQLM 320
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
++ +A + K+ + ++ EL EL + QVQ + +
Sbjct: 321 TLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQ 380
Query: 734 RQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN---MEDAQ 790
+ ++ L+E + A + L+T R+ + + E +A R +E+ Q
Sbjct: 381 KLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQ 440
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
T+ + ++ E EL + + QE+ + + E+ RL + RA
Sbjct: 441 GRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRA 500
Query: 851 LGHTELSRA 859
L +A
Sbjct: 501 QADLALEKA 509
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 56.8 bits (131), Expect = 3e-07
Identities = 69/282 (24%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 595 DELENENKSLRRQRVDNNVAHLQ---DELIAVKLREAEANLSLKDLRQRVSEL------- 644
+E EN +L+ QR++ + L+ +EL VK+ + ++DL+ ++SE+
Sbjct: 659 NEKVEENSTLQ-QRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSA 717
Query: 645 --SESWQR-----HLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
SE ++ L + KQ+ + D++ ++ L A +G + + ++
Sbjct: 718 KRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQE 777
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQV--STNQLRRQDE-----EARLLRENLDAAL 750
M + +A EL+ LR V E V+V S + QD+ +LL+E +
Sbjct: 778 MDKLKEQYDA--ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQ 835
Query: 751 QRERALQTRQREFQHKYADL---ESKAK--YESMQANIRNMEDA---QRIAELETEVSEY 802
R L+ R + Q + DL E+KAK + + IR +E+A R E E +
Sbjct: 836 GRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARR 895
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
L+NE+ A +G L + +L+E+ +E K ++ RL+
Sbjct: 896 ALENELEAAQGNLSQTTQEQKQLSEKLKEE-SEQKEQLRRLK 936
Score = 51.2 bits (117), Expect = 2e-05
Identities = 69/344 (20%), Positives = 142/344 (41%), Gaps = 15/344 (4%)
Query: 510 DREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCL 569
D E+QALR + + + + V + E A R L+ + EEL R +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 845
Query: 570 QXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAE 629
E+ ++L R + A + +L A+
Sbjct: 846 AQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQ 905
Query: 630 ANLS--LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
NLS ++ +Q +L E ++ Q + + + ++ I K++ E
Sbjct: 906 GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 965
Query: 688 ADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQ---VQVSTNQLRRQDEEARLLR 743
L+L +L + + L E+ ++L+ K +E E +++R +EE R +
Sbjct: 966 TSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQ 1025
Query: 744 ENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN-IRNMEDAQRIAELETEVSEY 802
D AL + + L+ ++ ++ +LE+K+ + ++ ++ MED ++++LE E+ E
Sbjct: 1026 RAQDEALTKRQLLEQTLKDLEY---ELEAKSHLKDDRSRLVKQMED--KVSQLEMELEEE 1080
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVA--ELKAEIMRLE 844
+ N + +E R+ + R LQE+ A +L+ + + LE
Sbjct: 1081 R-NNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLE 1123
Score = 33.9 bits (74), Expect = 2.6
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 17/159 (10%)
Query: 704 EVEALTELK-ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD-------AALQRERA 755
EV+ L E K +L ++V EL+ Q+Q+ + EE +R NL+ ++
Sbjct: 608 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENST 667
Query: 756 LQTRQREFQHKY-ADLES----KAKYESMQANIRNMEDAQRIAELETEVSEYKLK--NEV 808
LQ R E + + +LE K + E Q IR+++D +++E+ E+ K E
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQD--QLSEMHDELDSAKRSEDREK 725
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
A EL D D + +EQ L+ L A K
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 56.8 bits (131), Expect = 3e-07
Identities = 69/282 (24%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 595 DELENENKSLRRQRVDNNVAHLQ---DELIAVKLREAEANLSLKDLRQRVSEL------- 644
+E EN +L+ QR++ + L+ +EL VK+ + ++DL+ ++SE+
Sbjct: 659 NEKVEENSTLQ-QRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSA 717
Query: 645 --SESWQR-----HLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
SE ++ L + KQ+ + D++ ++ L A +G + + ++
Sbjct: 718 KRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQE 777
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQV--STNQLRRQDE-----EARLLRENLDAAL 750
M + +A EL+ LR V E V+V S + QD+ +LL+E +
Sbjct: 778 MDKLKEQYDA--ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQ 835
Query: 751 QRERALQTRQREFQHKYADL---ESKAK--YESMQANIRNMEDA---QRIAELETEVSEY 802
R L+ R + Q + DL E+KAK + + IR +E+A R E E +
Sbjct: 836 GRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARR 895
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
L+NE+ A +G L + +L+E+ +E K ++ RL+
Sbjct: 896 ALENELEAAQGNLSQTTQEQKQLSEKLKEE-SEQKEQLRRLK 936
Score = 51.2 bits (117), Expect = 2e-05
Identities = 69/344 (20%), Positives = 142/344 (41%), Gaps = 15/344 (4%)
Query: 510 DREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCL 569
D E+QALR + + + + V + E A R L+ + EEL R +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 845
Query: 570 QXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAE 629
E+ ++L R + A + +L A+
Sbjct: 846 AQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQ 905
Query: 630 ANLS--LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
NLS ++ +Q +L E ++ Q + + + ++ I K++ E
Sbjct: 906 GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 965
Query: 688 ADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQ---VQVSTNQLRRQDEEARLLR 743
L+L +L + + L E+ ++L+ K +E E +++R +EE R +
Sbjct: 966 TSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQ 1025
Query: 744 ENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN-IRNMEDAQRIAELETEVSEY 802
D AL + + L+ ++ ++ +LE+K+ + ++ ++ MED ++++LE E+ E
Sbjct: 1026 RAQDEALTKRQLLEQTLKDLEY---ELEAKSHLKDDRSRLVKQMED--KVSQLEMELEEE 1080
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVA--ELKAEIMRLE 844
+ N + +E R+ + R LQE+ A +L+ + + LE
Sbjct: 1081 R-NNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLE 1123
Score = 33.9 bits (74), Expect = 2.6
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 17/159 (10%)
Query: 704 EVEALTELK-ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD-------AALQRERA 755
EV+ L E K +L ++V EL+ Q+Q+ + EE +R NL+ ++
Sbjct: 608 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENST 667
Query: 756 LQTRQREFQHKY-ADLES----KAKYESMQANIRNMEDAQRIAELETEVSEYKLK--NEV 808
LQ R E + + +LE K + E Q IR+++D +++E+ E+ K E
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQD--QLSEMHDELDSAKRSEDREK 725
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
A EL D D + +EQ L+ L A K
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 56.8 bits (131), Expect = 3e-07
Identities = 69/282 (24%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 595 DELENENKSLRRQRVDNNVAHLQ---DELIAVKLREAEANLSLKDLRQRVSEL------- 644
+E EN +L+ QR++ + L+ +EL VK+ + ++DL+ ++SE+
Sbjct: 659 NEKVEENSTLQ-QRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSA 717
Query: 645 --SESWQR-----HLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
SE ++ L + KQ+ + D++ ++ L A +G + + ++
Sbjct: 718 KRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQE 777
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQV--STNQLRRQDE-----EARLLRENLDAAL 750
M + +A EL+ LR V E V+V S + QD+ +LL+E +
Sbjct: 778 MDKLKEQYDA--ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQ 835
Query: 751 QRERALQTRQREFQHKYADL---ESKAK--YESMQANIRNMEDA---QRIAELETEVSEY 802
R L+ R + Q + DL E+KAK + + IR +E+A R E E +
Sbjct: 836 GRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARR 895
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
L+NE+ A +G L + +L+E+ +E K ++ RL+
Sbjct: 896 ALENELEAAQGNLSQTTQEQKQLSEKLKEE-SEQKEQLRRLK 936
Score = 51.2 bits (117), Expect = 2e-05
Identities = 69/344 (20%), Positives = 142/344 (41%), Gaps = 15/344 (4%)
Query: 510 DREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCL 569
D E+QALR + + + + V + E A R L+ + EEL R +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 845
Query: 570 QXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAE 629
E+ ++L R + A + +L A+
Sbjct: 846 AQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQ 905
Query: 630 ANLS--LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
NLS ++ +Q +L E ++ Q + + + ++ I K++ E
Sbjct: 906 GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 965
Query: 688 ADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQ---VQVSTNQLRRQDEEARLLR 743
L+L +L + + L E+ ++L+ K +E E +++R +EE R +
Sbjct: 966 TSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQ 1025
Query: 744 ENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN-IRNMEDAQRIAELETEVSEY 802
D AL + + L+ ++ ++ +LE+K+ + ++ ++ MED ++++LE E+ E
Sbjct: 1026 RAQDEALTKRQLLEQTLKDLEY---ELEAKSHLKDDRSRLVKQMED--KVSQLEMELEEE 1080
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVA--ELKAEIMRLE 844
+ N + +E R+ + R LQE+ A +L+ + + LE
Sbjct: 1081 R-NNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLE 1123
Score = 33.9 bits (74), Expect = 2.6
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 17/159 (10%)
Query: 704 EVEALTELK-ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD-------AALQRERA 755
EV+ L E K +L ++V EL+ Q+Q+ + EE +R NL+ ++
Sbjct: 608 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENST 667
Query: 756 LQTRQREFQHKY-ADLES----KAKYESMQANIRNMEDAQRIAELETEVSEYKLK--NEV 808
LQ R E + + +LE K + E Q IR+++D +++E+ E+ K E
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQD--QLSEMHDELDSAKRSEDREK 725
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
A EL D D + +EQ L+ L A K
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 56.8 bits (131), Expect = 3e-07
Identities = 69/282 (24%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 595 DELENENKSLRRQRVDNNVAHLQ---DELIAVKLREAEANLSLKDLRQRVSEL------- 644
+E EN +L+ QR++ + L+ +EL VK+ + ++DL+ ++SE+
Sbjct: 659 NEKVEENSTLQ-QRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSA 717
Query: 645 --SESWQR-----HLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
SE ++ L + KQ+ + D++ ++ L A +G + + ++
Sbjct: 718 KRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQE 777
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQV--STNQLRRQDE-----EARLLRENLDAAL 750
M + +A EL+ LR V E V+V S + QD+ +LL+E +
Sbjct: 778 MDKLKEQYDA--ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQ 835
Query: 751 QRERALQTRQREFQHKYADL---ESKAK--YESMQANIRNMEDA---QRIAELETEVSEY 802
R L+ R + Q + DL E+KAK + + IR +E+A R E E +
Sbjct: 836 GRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARR 895
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
L+NE+ A +G L + +L+E+ +E K ++ RL+
Sbjct: 896 ALENELEAAQGNLSQTTQEQKQLSEKLKEE-SEQKEQLRRLK 936
Score = 51.2 bits (117), Expect = 2e-05
Identities = 69/344 (20%), Positives = 142/344 (41%), Gaps = 15/344 (4%)
Query: 510 DREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCL 569
D E+QALR + + + + V + E A R L+ + EEL R +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 845
Query: 570 QXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAE 629
E+ ++L R + A + +L A+
Sbjct: 846 AQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQ 905
Query: 630 ANLS--LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
NLS ++ +Q +L E ++ Q + + + ++ I K++ E
Sbjct: 906 GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 965
Query: 688 ADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQ---VQVSTNQLRRQDEEARLLR 743
L+L +L + + L E+ ++L+ K +E E +++R +EE R +
Sbjct: 966 TSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQ 1025
Query: 744 ENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN-IRNMEDAQRIAELETEVSEY 802
D AL + + L+ ++ ++ +LE+K+ + ++ ++ MED ++++LE E+ E
Sbjct: 1026 RAQDEALTKRQLLEQTLKDLEY---ELEAKSHLKDDRSRLVKQMED--KVSQLEMELEEE 1080
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVA--ELKAEIMRLE 844
+ N + +E R+ + R LQE+ A +L+ + + LE
Sbjct: 1081 R-NNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLE 1123
Score = 33.9 bits (74), Expect = 2.6
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 17/159 (10%)
Query: 704 EVEALTELK-ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD-------AALQRERA 755
EV+ L E K +L ++V EL+ Q+Q+ + EE +R NL+ ++
Sbjct: 608 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENST 667
Query: 756 LQTRQREFQHKY-ADLES----KAKYESMQANIRNMEDAQRIAELETEVSEYKLK--NEV 808
LQ R E + + +LE K + E Q IR+++D +++E+ E+ K E
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQD--QLSEMHDELDSAKRSEDREK 725
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
A EL D D + +EQ L+ L A K
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 56.8 bits (131), Expect = 3e-07
Identities = 69/282 (24%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 595 DELENENKSLRRQRVDNNVAHLQ---DELIAVKLREAEANLSLKDLRQRVSEL------- 644
+E EN +L+ QR++ + L+ +EL VK+ + ++DL+ ++SE+
Sbjct: 404 NEKVEENSTLQ-QRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSA 462
Query: 645 --SESWQR-----HLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
SE ++ L + KQ+ + D++ ++ L A +G + + ++
Sbjct: 463 KRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQE 522
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQV--STNQLRRQDE-----EARLLRENLDAAL 750
M + +A EL+ LR V E V+V S + QD+ +LL+E +
Sbjct: 523 MDKLKEQYDA--ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQ 580
Query: 751 QRERALQTRQREFQHKYADL---ESKAK--YESMQANIRNMEDA---QRIAELETEVSEY 802
R L+ R + Q + DL E+KAK + + IR +E+A R E E +
Sbjct: 581 GRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARR 640
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
L+NE+ A +G L + +L+E+ +E K ++ RL+
Sbjct: 641 ALENELEAAQGNLSQTTQEQKQLSEKLKEE-SEQKEQLRRLK 681
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/344 (20%), Positives = 142/344 (41%), Gaps = 15/344 (4%)
Query: 510 DREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCL 569
D E+QALR + + + + V + E A R L+ + EEL R +
Sbjct: 531 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 590
Query: 570 QXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAE 629
E+ ++L R + A + +L A+
Sbjct: 591 AQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQ 650
Query: 630 ANLS--LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
NLS ++ +Q +L E ++ Q + + + ++ I K++ E
Sbjct: 651 GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 710
Query: 688 ADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQ---VQVSTNQLRRQDEEARLLR 743
L+L +L + + L E+ ++L+ K +E E +++R +EE R +
Sbjct: 711 TSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQ 770
Query: 744 ENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN-IRNMEDAQRIAELETEVSEY 802
D AL + + L+ ++ ++ +LE+K+ + ++ ++ MED ++++LE E+ E
Sbjct: 771 RAQDEALTKRQLLEQTLKDLEY---ELEAKSHLKDDRSRLVKQMED--KVSQLEMELEEE 825
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVA--ELKAEIMRLE 844
+ N + +E R+ + R LQE+ A +L+ + + LE
Sbjct: 826 R-NNSDLLSERISRSREQMEQVRNELLQERAARQDLECDKISLE 868
Score = 33.9 bits (74), Expect = 2.6
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 17/159 (10%)
Query: 704 EVEALTELK-ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD-------AALQRERA 755
EV+ L E K +L ++V EL+ Q+Q+ + EE +R NL+ ++
Sbjct: 353 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENST 412
Query: 756 LQTRQREFQHKY-ADLES----KAKYESMQANIRNMEDAQRIAELETEVSEYKLK--NEV 808
LQ R E + + +LE K + E Q IR+++D +++E+ E+ K E
Sbjct: 413 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQD--QLSEMHDELDSAKRSEDREK 470
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
A EL D D + +EQ L+ L A K
Sbjct: 471 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 509
>Z99127-3|CAI18933.1| 370|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 370
Score = 55.6 bits (128), Expect = 7e-07
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 372 ACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--F 429
ACR++++ L G + LL K DLL D E LK+ + +LP + A++ A
Sbjct: 36 ACRVLEL-LGMGHRLFVP---RLLATSKEDLLQADFEGALKFFRVQLPKRYRAEENARRL 91
Query: 430 MNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXX 489
M A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 92 MEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLA 151
Query: 490 XXXVRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 152 HELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 204
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 90 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 143
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 144 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 202
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 203 LK-EVFRKQLEKA 214
>AL161671-2|CAI16277.1| 370|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 370
Score = 55.6 bits (128), Expect = 7e-07
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 372 ACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--F 429
ACR++++ L G + LL K DLL D E LK+ + +LP + A++ A
Sbjct: 36 ACRVLEL-LGMGHRLFVP---RLLATSKEDLLQADFEGALKFFRVQLPKRYRAEENARRL 91
Query: 430 MNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXX 489
M A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 92 MEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLA 151
Query: 490 XXXVRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 152 HELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 204
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 90 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 143
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 144 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 202
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 203 LK-EVFRKQLEKA 214
>AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein.
Length = 1257
Score = 55.6 bits (128), Expect = 7e-07
Identities = 74/350 (21%), Positives = 155/350 (44%), Gaps = 30/350 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSR--QSSLEGTESASGQ 560
EEE A ++E+ ALR NV +Q+++A + S + E + + L S
Sbjct: 206 EEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTD 265
Query: 561 KHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDEL 620
+ ++ LQ + E+E E ++ R+ + + + +
Sbjct: 266 ETSQIVE-LQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQR 324
Query: 621 IAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLL 680
+REA A +D+ +R++ L +R+L ++ + + ++ +A + +L
Sbjct: 325 ---DIREAMA--QKEDMEERITTLE---KRYLSAQRESTSIHDMNDKLENE-LANKEAIL 375
Query: 681 RAWEGRSADM---LKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQVSTN-QLRRQ 735
R E ++ + L+L EE + +R+ E L E++ EL ++ L + N + R +
Sbjct: 376 RQMEEKNRQLQERLELAEEKLQQTMRKAETLPEVEAELAQRIAALTKAEETHGNIEERMR 435
Query: 736 DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAEL 795
E +L +N + LQR R + E + +D + ES + +++ +R+A L
Sbjct: 436 HLEGQLEEKNQE--LQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLK--ERMAAL 491
Query: 796 ETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLE 844
E + V+ E E N+++S +E L E++ +L++E+ +L+
Sbjct: 492 E--------EKNVLIQESETFRKNLEESLHDKESLAEEIEKLRSELDQLK 533
>AB007940-1|BAA32316.2| 413|Homo sapiens KIAA0471 protein protein.
Length = 413
Score = 55.6 bits (128), Expect = 7e-07
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 372 ACRIMDVFLSEGIEIVFKVALALLTLGKNDLLSLDMESILKYIQKELPLKAEADQAA--F 429
ACR++++ L G + LL K DLL D E LK+ + +LP + A++ A
Sbjct: 79 ACRVLEL-LGMGHRLFVP---RLLATSKEDLLQADFEGALKFFRVQLPKRYRAEENARRL 134
Query: 430 MNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXX 489
M A ++KV KK+KK EKEY ++ + + ++ENR L++
Sbjct: 135 MEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLA 194
Query: 490 XXXVRGQV----DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLE 538
V ++ D + E++ L++E+ ++ V+ ++ +E L+
Sbjct: 195 HELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLK 247
Score = 33.1 bits (72), Expect = 4.5
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 9/133 (6%)
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
++ME ++V T +L++ ++E + +RE + LQ+E + +RE + E+ +
Sbjct: 133 RLMEQACNIKVPTKKLKKYEKEYQTMRE---SQLQQEDPMDRYKRENRRLQ---EASMRL 186
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM-DDSDRVRELQEQVAE 835
E ++ + +IA L ++ + + K +V+ E L + + + R+ +E+ A+
Sbjct: 187 EQENDDLAHELVTSKIA-LRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQ 245
Query: 836 LKAEIMRLEAWKS 848
LK E+ R + K+
Sbjct: 246 LK-EVFRKQLEKA 257
>BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein.
Length = 913
Score = 55.2 bits (127), Expect = 1e-06
Identities = 76/369 (20%), Positives = 160/369 (43%), Gaps = 34/369 (9%)
Query: 500 AEGEEETFALDRE-----VQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGT 554
AE E+E F L ++ + L NV + + + + + +S I E +R L G
Sbjct: 322 AEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGE 381
Query: 555 ESASG-------QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLR-R 606
S Q+ EL RC Q +++ E K L+ +
Sbjct: 382 AENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTK 441
Query: 607 QRVDNNVAHLQDELIAVK----LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAA 662
D N+ + L A K + E E N+ + + SEL Q QE+K + +
Sbjct: 442 YDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKS 501
Query: 663 PVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL-----MTTRIREVEALTELKELRLK 717
++ +L + E + K +E L TR+ EV+ L + ++
Sbjct: 502 HLKHIYEEKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRL-QAQQADAA 560
Query: 718 VMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ-REFQHKYADLESKAKY 776
+ E + QV++++ ++ + +E E ++A L R ++L+ +Q +EF + D+ + +
Sbjct: 561 LEEFKRQVELNSEKVYAEMKEQM---EKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQ 617
Query: 777 ESMQANIRNMEDA-----QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
+ ++ + + ++ Q AE ++ V +++ E+ E +LR NM+ ++++E ++
Sbjct: 618 QIVELKLEHEQEKTHLLQQHNAEKDSLVRDHE--REIENLEKQLRAANMEHENQIQEFKK 675
Query: 832 QVAELKAEI 840
+ A++ A++
Sbjct: 676 RDAQVIADM 684
Score = 41.1 bits (92), Expect = 0.017
Identities = 60/281 (21%), Positives = 121/281 (43%), Gaps = 27/281 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAE-------ANLSLKDLRQRVSELS- 645
+ E+E E L++Q +N L+D + + E+E N +K+L RV +L+
Sbjct: 321 VAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTG 380
Query: 646 ESWQRHLQEHK--QEAP----AAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
E+ +LQ K QE + + + ++ A L + + D + + L T
Sbjct: 381 EAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQT 440
Query: 700 TRIREVEALTELKELRL-KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
++ L + L K + +++ + QL++Q +E+ L R+ +E Q
Sbjct: 441 KYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRK--QQLRDQENKFQM 498
Query: 759 RQREFQHKYA----DLESKAK--YESMQANIRNMEDAQRIAELE----TEVSEYKLKNEV 808
+ +H Y DL+S+ E Q I E+A + E + TEV + +
Sbjct: 499 EKSHLKHIYEEKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQAD 558
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSR 849
A E R ++ E++EQ+ +++A++ R ++ + +
Sbjct: 559 AALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREK 599
Score = 39.1 bits (87), Expect = 0.068
Identities = 50/237 (21%), Positives = 104/237 (43%), Gaps = 28/237 (11%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
+LE+ + +Q V+ + H Q++ ++ AE + ++D + + L + + EH
Sbjct: 607 QLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEH 666
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+ N + + +++ E A + KL EEL+ + + L EL LR
Sbjct: 667 E----------NQIQEFKKRDAQVIADME---AQVHKLREELINVNSQRKQQLVELGLLR 713
Query: 716 LKVMELETQV-QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
+ + T+ ++ N+L+ + E+ ++ + AA + E L+ SK
Sbjct: 714 EEEKQRATREHEIVVNKLKAESEKMKIELKKTHAA-ETEMTLEKAN-----------SKL 761
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKN--EVMATEGELRNNNMDDSDRVREL 829
K + + + +Q IAEL+T +S K +N + +A E L++ D ++L
Sbjct: 762 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 818
Score = 38.7 bits (86), Expect = 0.090
Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 23/207 (11%)
Query: 634 LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKL 693
L+D+RQR + + EH+QE Q N D L+R E ++ L
Sbjct: 608 LEDIRQRYEQQIVELKL---EHEQEKTHLLQQHNAEKD------SLVRDHE---REIENL 655
Query: 694 DEELMTTRIREVEALTELKELRLKVM-ELETQVQVSTNQLRRQDEEARLLRENLDAALQR 752
+++L + + E K+ +V+ ++E QV +L + + + ++ ++ L R
Sbjct: 656 EKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRK--QQLVELGLLR 713
Query: 753 ERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATE 812
E Q RE H+ + KA+ E M+ ++ A ETE++ K +++ E
Sbjct: 714 EEEKQRATRE--HEIVVNKLKAESEKMKIELKKTHAA------ETEMTLEKANSKLKQIE 765
Query: 813 GELRNNNMDDSDRVRELQEQVAELKAE 839
E S + ELQ ++ LK E
Sbjct: 766 KEYTQKLAKSSQIIAELQTTISSLKEE 792
Score = 36.7 bits (81), Expect = 0.36
Identities = 38/173 (21%), Positives = 75/173 (43%), Gaps = 6/173 (3%)
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQV-STNQLRRQDEEA--RLLRE 744
A+M + +L ++ L E +RL ME E Q STN + ++ E +L E
Sbjct: 322 AEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGE 381
Query: 745 NLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVS--EY 802
++ LQR++ +Q + E + Y S+ + + N + E + + E + +
Sbjct: 382 AENSNLQRQKLIQEKA-ELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQT 440
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
K ++ + E + S + EL++ V +LK ++ E + + L E
Sbjct: 441 KYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQE 493
Score = 33.9 bits (74), Expect = 2.6
Identities = 48/220 (21%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL-SESWQRHL 652
I ++E + LR + ++ N Q + LRE E + ++ V++L +ES + +
Sbjct: 681 IADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKI 740
Query: 653 QEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+ K A + + + K++ + + + A ++ EL TT ++ LK
Sbjct: 741 ELKKTHAAETEMTLEKANSKL---KQIEKEYTQKLAKSSQIIAELQTT-------ISSLK 790
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDA--ALQRE---RALQTR--QREFQH 765
E + +L + ++ + + +DE+ +L+R+N A LQ E R+ Q R +++ QH
Sbjct: 791 EENSQ-QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQH 849
Query: 766 KYADLESKAKY--ESMQANIRNMEDAQRIAELETEVSEYK 803
K + + + Y + + ++ + A ELE +S K
Sbjct: 850 KELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLK 889
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1435 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1494
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1495 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEA 1554
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1555 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1613
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1614 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1673
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1674 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1733
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1734 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1793
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1794 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1850
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1851 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1910
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1911 AAQHKADIEERLA-QLRKASDSELER 1935
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEA 2069
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2070 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2124
Query: 616 LQDELIAVKL-REAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2125 VQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2178
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2239 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2292
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2293 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2351
Query: 848 SRA 850
+A
Sbjct: 2352 LKA 2354
Score = 47.2 bits (107), Expect = 3e-04
Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E R R+VE
Sbjct: 2085 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQAR-RQVEEAER 2143
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2144 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2203
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2204 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2260
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2261 RVQMEELSKLKA---RIEA-ENRAL 2281
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/280 (20%), Positives = 114/280 (40%), Gaps = 17/280 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1371 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1430
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1431 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1490
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRER--ALQTRQREFQ 764
+ ++ L + + + Q R+ EEA LR + QR+R ++ R
Sbjct: 1491 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1550
Query: 765 HKYADLESKAKYESMQANIRNMEDAQ-RIAELETEVS---EYKLKNEVMATEGELRNNNM 820
A E + ++++ E+A+ R+ + E E + + L+ + E EL++
Sbjct: 1551 ETEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1610
Query: 821 DDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1650
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2163 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2221
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2222 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2278
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2279 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2337
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2338 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2388
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2389 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2448
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2449 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2508
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2509 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2564
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2565 QQQMEQERQRLVASME 2580
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1798 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1851
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1852 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1899
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1900 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1959
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1960 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 2019
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 2020 SLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2079
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2080 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVE 2139
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2140 EAERLKQSA 2148
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1435 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1494
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1495 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEA 1554
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1555 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1613
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1614 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1673
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1674 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1733
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1734 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1793
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1794 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1850
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1851 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1910
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1911 AAQHKADIEERLA-QLRKASDSELER 1935
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEA 2069
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2070 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2124
Query: 616 LQDELIAVKL-REAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2125 VQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2178
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2239 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2292
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2293 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2351
Query: 848 SRA 850
+A
Sbjct: 2352 LKA 2354
Score = 47.2 bits (107), Expect = 3e-04
Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E R R+VE
Sbjct: 2085 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQAR-RQVEEAER 2143
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2144 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2203
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2204 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2260
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2261 RVQMEELSKLKA---RIEA-ENRAL 2281
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/280 (20%), Positives = 114/280 (40%), Gaps = 17/280 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1371 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1430
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1431 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1490
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRER--ALQTRQREFQ 764
+ ++ L + + + Q R+ EEA LR + QR+R ++ R
Sbjct: 1491 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1550
Query: 765 HKYADLESKAKYESMQANIRNMEDAQ-RIAELETEVS---EYKLKNEVMATEGELRNNNM 820
A E + ++++ E+A+ R+ + E E + + L+ + E EL++
Sbjct: 1551 ETEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRA 1610
Query: 821 DDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1650
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2163 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2221
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2222 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2278
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2279 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2337
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2338 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2388
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2389 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2448
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2449 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2508
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2509 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2564
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2565 QQQMEQERQRLVASME 2580
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1798 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1851
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1852 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1899
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1900 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1959
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1960 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 2019
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 2020 SLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2079
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2080 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVE 2139
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2140 EAERLKQSA 2148
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1408 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1467
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1468 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1527
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1528 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1586
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1587 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1646
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1647 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1706
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1766
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1767 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1884 AAQHKADIEERLA-QLRKASDSELER 1908
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2043 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2097
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2098 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2151
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2212 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2265
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2266 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2324
Query: 848 SRA 850
+A
Sbjct: 2325 LKA 2327
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2058 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2116
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2176
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2177 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2233
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2234 RVQMEELSKLKA---RIEA-ENRAL 2254
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1464 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1523
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1524 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1582
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1583 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1623
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2136 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2194
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2195 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2251
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2252 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2311 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2361
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2362 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2421
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2422 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2481
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2482 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2537
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2538 QQQMEQERQRLVASME 2553
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1771 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1824
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1825 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1872
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1932
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1933 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 1992
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 1993 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2052
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2053 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2112
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2113 EAERLKQSA 2121
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1412 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1471
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1472 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1531
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1532 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1590
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1591 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1650
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1651 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1710
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1711 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1770
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1771 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1827
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1828 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1887
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1888 AAQHKADIEERLA-QLRKASDSELER 1912
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 1987 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2046
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2047 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2101
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2102 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2155
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2156 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2215
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2216 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2269
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2270 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2328
Query: 848 SRA 850
+A
Sbjct: 2329 LKA 2331
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2062 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2120
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2121 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2180
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2181 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2237
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2238 RVQMEELSKLKA---RIEA-ENRAL 2258
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1348 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1407
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1408 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1467
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1468 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1527
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1528 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1586
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1587 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1627
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2140 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2198
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2199 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2255
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2256 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2314
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2315 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2365
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2366 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2425
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2426 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2485
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2486 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2541
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2542 QQQMEQERQRLVASME 2557
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1775 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1828
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1829 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1876
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1877 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1936
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1937 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 1996
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 1997 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2056
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2057 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2116
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2117 EAERLKQSA 2125
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1408 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1467
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1468 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1527
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1528 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1586
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1587 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1646
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1647 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1706
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1766
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1767 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1884 AAQHKADIEERLA-QLRKASDSELER 1908
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2043 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2097
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2098 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2151
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2212 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2265
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2266 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2324
Query: 848 SRA 850
+A
Sbjct: 2325 LKA 2327
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2058 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2116
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2176
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2177 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2233
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2234 RVQMEELSKLKA---RIEA-ENRAL 2254
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1464 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1523
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1524 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1582
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1583 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1623
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2136 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2194
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2195 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2251
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2252 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2311 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2361
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2362 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2421
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2422 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2481
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2482 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2537
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2538 QQQMEQERQRLVASME 2553
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1771 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1824
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1825 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1872
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1932
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1933 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 1992
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 1993 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2052
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2053 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2112
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2113 EAERLKQSA 2121
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1376 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1435
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1436 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1495
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1496 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1554
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1555 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1614
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1615 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1674
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1675 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1734
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1735 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1791
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1792 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1851
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1852 AAQHKADIEERLA-QLRKASDSELER 1876
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 1951 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2010
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2011 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2065
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2066 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2119
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2120 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2179
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2180 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2233
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2234 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2292
Query: 848 SRA 850
+A
Sbjct: 2293 LKA 2295
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2026 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2084
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2085 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2144
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2145 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2201
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2202 RVQMEELSKLKA---RIEA-ENRAL 2222
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1312 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1371
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1372 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1431
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1432 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1491
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1492 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1550
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1551 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1591
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2104 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2162
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2163 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2219
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2220 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2278
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2279 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2329
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2330 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2389
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2390 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2449
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2450 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2505
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2506 QQQMEQERQRLVASME 2521
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1739 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1792
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1793 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1840
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1841 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1900
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1901 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 1960
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 1961 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2020
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2021 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2080
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2081 EAERLKQSA 2089
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1545 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1604
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1605 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1664
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1665 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1723
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1724 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1783
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1784 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1843
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1844 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1903
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1904 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1960
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1961 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 2020
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 2021 AAQHKADIEERLA-QLRKASDSELER 2045
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2179
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2180 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2234
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2235 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2288
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2289 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2348
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2349 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2402
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2403 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2461
Query: 848 SRA 850
+A
Sbjct: 2462 LKA 2464
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2195 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2253
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2254 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2313
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2314 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2370
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2371 RVQMEELSKLKA---RIEA-ENRAL 2391
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1481 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1540
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1600
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1601 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1660
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1661 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1719
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1720 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1760
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2273 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2331
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2332 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2388
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2389 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2447
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2448 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2498
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2499 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2558
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2559 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2618
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2619 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2674
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2675 QQQMEQERQRLVASME 2690
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1908 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1961
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1962 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 2009
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 2010 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 2069
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 2070 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 2129
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 2130 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2189
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2190 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2249
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2250 EAERLKQSA 2258
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1386 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1445
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1446 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1505
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1506 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1564
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1565 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1624
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1625 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1684
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1685 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1744
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1745 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1801
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1802 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1861
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1862 AAQHKADIEERLA-QLRKASDSELER 1886
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 1961 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2020
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2021 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2075
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2076 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2129
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2130 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2189
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2190 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2243
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2244 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2302
Query: 848 SRA 850
+A
Sbjct: 2303 LKA 2305
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2036 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2094
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2095 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2154
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2155 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2211
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2212 RVQMEELSKLKA---RIEA-ENRAL 2232
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1322 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1381
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1382 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1441
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1442 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1501
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1502 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1560
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1561 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1601
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2114 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2172
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2173 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2229
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2230 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2288
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2289 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2339
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2340 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2399
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2400 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2459
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2460 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2515
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2516 QQQMEQERQRLVASME 2531
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1749 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1802
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1803 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1850
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1851 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1910
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1911 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 1970
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 1971 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2030
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2031 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2090
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2091 EAERLKQSA 2099
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1394 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1453
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1454 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1513
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1514 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1572
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1573 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1632
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1633 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1692
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1693 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1752
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1753 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1809
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1810 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1869
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1870 AAQHKADIEERLA-QLRKASDSELER 1894
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 1969 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2028
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2029 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2083
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2084 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2137
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2138 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2197
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2198 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2251
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2252 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2310
Query: 848 SRA 850
+A
Sbjct: 2311 LKA 2313
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2044 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2102
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2103 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2162
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2163 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2219
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2220 RVQMEELSKLKA---RIEA-ENRAL 2240
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1330 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1389
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1390 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1449
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1450 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1509
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1510 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1568
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1569 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1609
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2122 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2180
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2181 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2237
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2238 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2296
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2297 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2347
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2348 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2407
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2408 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2467
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2468 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2523
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2524 QQQMEQERQRLVASME 2539
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1757 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1810
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1811 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1858
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1859 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1918
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1919 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 1978
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 1979 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2038
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2039 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2098
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2099 EAERLKQSA 2107
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 54.8 bits (126), Expect = 1e-06
Identities = 109/506 (21%), Positives = 200/506 (39%), Gaps = 56/506 (11%)
Query: 404 SLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIK-----TKEQ 458
++D + + IQ+EL ++ +A A + + ++E+E V++ T+ Q
Sbjct: 1435 AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1494
Query: 459 -----GDIAVLRCLRQE------------NRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
G++ LR +E RL +Q R + +
Sbjct: 1495 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1554
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVA-LDEIRSLEMTI-AENNSRQSSLEGTESASG 559
E+ AL + ++ LR + ++RL A ++ R +++ + S ++ L+ ++
Sbjct: 1555 AREKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1613
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA---HL 616
+K +L R LQ E + L R ++ N A L
Sbjct: 1614 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1673
Query: 617 QDELIAVK--LREAEANLSLKDL-----RQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
Q E +A + L +AEA ++ R+ +E QR L E + E +
Sbjct: 1674 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1733
Query: 670 SDIMATPKKL-LRAWEGRSADMLKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQV 727
+ A + + LRA + +L EE + RE A T+ + EL ++ ++ +++V
Sbjct: 1734 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV 1793
Query: 728 STNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNME 787
R +EE+R E + QR A R RE + A L + A+ Q + +
Sbjct: 1794 LLASKARAEEESRSTSEK---SKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1850
Query: 788 DAQRIAELET----------EVSEYKLKNEVMATEGELRNNNM-----DDSDRVRELQEQ 832
A++ AE E E + K + E+ E E N + D++ + R L+EQ
Sbjct: 1851 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1910
Query: 833 VAELKAEIMRLEAWKSRALGHTELSR 858
A+ KA+I A + R +EL R
Sbjct: 1911 AAQHKADIEERLA-QLRKASDSELER 1935
Score = 49.6 bits (113), Expect = 5e-05
Identities = 79/363 (21%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2069
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 2070 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2124
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2125 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2178
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2239 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2292
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2293 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2351
Query: 848 SRA 850
+A
Sbjct: 2352 LKA 2354
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E +R R+VE
Sbjct: 2085 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAER 2143
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 2144 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2203
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 2204 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 2260
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 2261 RVQMEELSKLKA---RIEA-ENRAL 2281
Score = 45.2 bits (102), Expect = 0.001
Identities = 57/281 (20%), Positives = 114/281 (40%), Gaps = 19/281 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1371 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1430
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1431 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1490
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
+ ++ L + + + Q R+ EEA LR + QR+R +
Sbjct: 1491 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1550
Query: 767 YADLESKAKYESMQA----NIRNMEDAQRIAELETEVS---EYKLKNEVMATEGELRNNN 819
A+ ++ K ++QA ++ E +R+ + E E + + L+ + E EL++
Sbjct: 1551 EAE-AAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKR 1609
Query: 820 MDDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1610 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1650
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2163 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2221
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2222 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2278
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2279 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2337
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2338 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2388
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2389 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2448
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2449 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2508
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2509 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2564
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2565 QQQMEQERQRLVASME 2580
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1798 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1851
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1852 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 1899
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 1900 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1959
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 1960 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 2019
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 2020 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2079
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2080 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2139
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2140 EAERLKQSA 2148
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/282 (24%), Positives = 127/282 (45%), Gaps = 36/282 (12%)
Query: 595 DELENENKSLRRQRVDNNVAHLQ---DELIAVKLREAEANLSLKDLRQRVSEL------- 644
+E EN +L+ QR++ + L+ +EL VK+ + ++DL+ ++SE+
Sbjct: 659 NEKVEENSTLQ-QRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSA 717
Query: 645 --SESWQR-----HLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
SE ++ L + KQ+ + D++ ++ L A +G + + ++
Sbjct: 718 KRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQE 777
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQV--STNQLRRQDE-----EARLLRENLDAAL 750
M + +A EL+ LR V E V+V S + QD+ +LL+E +
Sbjct: 778 MDKLKEQYDA--ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQ 835
Query: 751 QRERALQTRQREFQHKYADL---ESKAK--YESMQANIRNMEDA---QRIAELETEVSEY 802
R L+ R + Q + DL E+KAK + + IR +E+A R E E +
Sbjct: 836 GRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARR 895
Query: 803 KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
L+NE+ +G L + +L+E+ +E K ++ RL+
Sbjct: 896 ALENELEGAQGNLSQTTQEQKQLSEKLKEE-SEQKEQLRRLK 936
Score = 46.0 bits (104), Expect = 6e-04
Identities = 65/336 (19%), Positives = 133/336 (39%), Gaps = 11/336 (3%)
Query: 510 DREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCL 569
D E+QALR + + + + V + E A R L+ + EEL R +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 845
Query: 570 QXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAE 629
E+ ++L R + A + +L A+
Sbjct: 846 AQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEGAQ 905
Query: 630 ANLS--LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
NLS ++ +Q +L E ++ Q + + + ++ I K++ E
Sbjct: 906 GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 965
Query: 688 ADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQVQVSTNQ---LRRQDEEARLLR 743
L+L +L + + L E+ ++L+ K +E E + +R +EE R +
Sbjct: 966 TSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQ 1025
Query: 744 ENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYK 803
D AL + + L+ ++ ++ +LE+K+ + ++ + +A ++++LE E+ E +
Sbjct: 1026 RAQDEALTKRQLLEQTLKDLEY---ELEAKSHLKDDRSRLVKQMEA-KVSQLEMELEEER 1081
Query: 804 LKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
N + +E R+ + R LQE+ A E
Sbjct: 1082 -NNSDLLSERISRSREQMEQLRNGLLQERAARQDLE 1116
Score = 33.1 bits (72), Expect = 4.5
Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 4/102 (3%)
Query: 704 EVEALTELK-ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQRE 762
EV+ L E K +L ++V EL+ Q+Q+ + EE +R NL+ +
Sbjct: 608 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENST 667
Query: 763 FQHKYADLESKAK---YESMQANIRNMEDAQRIAELETEVSE 801
Q + + E + + E Q + + I +L+ ++SE
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSE 709
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal
Nek2-associated protein 1 protein.
Length = 2442
Score = 54.4 bits (125), Expect = 2e-06
Identities = 85/380 (22%), Positives = 156/380 (41%), Gaps = 28/380 (7%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVAL----DEIRSLEMTIAENNSRQSSL 551
Q R E ++ L++E LRR NV++Q + A D+ L + + E Q L
Sbjct: 469 QKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEDQQEELHLAVRERERLQEML 528
Query: 552 EGTESASGQKHEELARCLQXXXXX------XXXXXXXXXXXXXXXXXXIDELENENKSLR 605
G E+ + EL + I EL + +L+
Sbjct: 529 MGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 588
Query: 606 RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQ 665
+ D A + +L A L EA A L L Q++ +L E Q + EA A +
Sbjct: 589 TEVADLRAAAV--KLSA--LNEALA-LDKVGLNQQLLQLEEENQSVCS--RMEA-AEQAR 640
Query: 666 SNVVSDIMATPKKLLRAWEGRS---ADMLKLDEELMTTRIREVEALTELKELRLKVMELE 722
+ + D+ K+ WE + A + K +E + + E +E++ K+ E
Sbjct: 641 NALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESR 700
Query: 723 TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN 782
Q + +T QL + +EA+ E L A+Q + AL + + + +E + +
Sbjct: 701 HQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDR--QDLAEQ 758
Query: 783 IRNMEDAQRIAELETEVSEYKLKNEVM-ATEGELRNNNMDDSDRVRELQEQVAELKAEI- 840
++ + A+ + LE+ + E + +N V+ T+G+L + +Q +V LK E+
Sbjct: 759 LQGLSSAKEL--LESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELD 816
Query: 841 -MRLEAWKSRALGHTELSRA 859
R +A + R +L++A
Sbjct: 817 TERSQAEQERDAAARQLAQA 836
Score = 47.2 bits (107), Expect = 3e-04
Identities = 66/332 (19%), Positives = 142/332 (42%), Gaps = 25/332 (7%)
Query: 512 EVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQX 571
+VQ L D + + E++ L+ +++N +S EG +++ + EL +
Sbjct: 1265 QVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMAS 1324
Query: 572 XXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEAN 631
E E ++ + V HLQ ++ + + + A
Sbjct: 1325 LQSRLRRAELQRMEAQG---------ERELLQAAKENLTAQVEHLQAAVVEARAQASAAG 1375
Query: 632 LSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADML 691
+ +DLR S L ++ ++ A A Q + +A K L + +
Sbjct: 1376 ILEEDLRTARSALKLK-NEEVESERERAQALQEQGELK---VAQGKALQENLALLTQTLA 1431
Query: 692 KLDEELMTTR--IREVEALTELKELRLKVMELETQ---VQVSTNQLRRQD-EEARLLREN 745
+ +EE+ T R I+E+E E+++ L+++ L+ + +V Q + Q+ E+ R + E+
Sbjct: 1432 EREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEH 1491
Query: 746 LDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELET-EVSEYK- 803
L A+Q T QRE Q + + + + + ++ + +E ++ E + +V + K
Sbjct: 1492 LPMAVQEREQKLTVQRE-QIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKK 1550
Query: 804 --LKNEVMATEGELRNNNMDDSDR-VRELQEQ 832
+ E +A E E ++ M+ + ++EL+ Q
Sbjct: 1551 QLVTLECLALELEENHHKMECQQKLIKELEGQ 1582
Score = 45.6 bits (103), Expect = 8e-04
Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 15/246 (6%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
E E +Q+ ++++ A++ +A+++LK+ + + E +R +E
Sbjct: 1818 ELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAV 1877
Query: 658 EAPAAPVQSNVVSDIMATPK---KLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
E V+ D+ A + K L A + + A+ + E + TR + L L
Sbjct: 1878 EGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQ--EHEVETRALQDSWLQAQAVL 1935
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
+ + ELE ++ + R Q+E AR E L AL + A Q + QH E
Sbjct: 1936 KERDQELEA-LRAESQSSRHQEEAARARAEALQEALGKAHA--ALQGKEQHLLEQAELSR 1992
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
E+ A ++ DA + +L+ + EGE+++ ++ + V++LQ+ +A
Sbjct: 1993 SLEASTATLQASLDA-------CQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALA 2045
Query: 835 ELKAEI 840
+ E+
Sbjct: 2046 QRDEEL 2051
Score = 42.3 bits (95), Expect = 0.007
Identities = 54/255 (21%), Positives = 107/255 (41%), Gaps = 19/255 (7%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+++E E + L+ Q+ + Q E + A + L+ ++RVS L + LQ
Sbjct: 883 EKMELEMR-LKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLL----ETLLQT 937
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE- 713
K+ A A+ + D+ K + + EL + + L L+E
Sbjct: 938 QKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 997
Query: 714 ---LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADL 770
L M+L+ QV+ +QL QD+ RL+ + + L+ + Q+E + + A L
Sbjct: 998 SSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASL 1057
Query: 771 ESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQ 830
+ + + D+ R EL L+ ++ +GE + + S ++ L+
Sbjct: 1058 TLSLMEKEQRLLVLQEADSIRQQELSA------LRQDMQEAQGEQK----ELSAQMELLR 1107
Query: 831 EQVAELKAEIMRLEA 845
++V E +A+ + EA
Sbjct: 1108 QEVKEKEADFLAQEA 1122
Score = 40.7 bits (91), Expect = 0.022
Identities = 59/272 (21%), Positives = 120/272 (44%), Gaps = 16/272 (5%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLR--EAEANLSLKDLRQR-VSELS--ESWQR 650
ELE +++ + QR V L+ +L+ ++ E E N + +Q+ + EL QR
Sbjct: 1530 ELEKKDQMIESQR--GQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQR 1587
Query: 651 HLQEH-----KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV 705
H ++ + QS+ + D+ + L R + R ++ E++ + R+
Sbjct: 1588 VALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQ-RQK 1646
Query: 706 EALTELKELRLKVMELETQ-VQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQ 764
E LT+ E R + + L+ + +QV +Q RQ + E + +L+ T QR+
Sbjct: 1647 EHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLM 1706
Query: 765 HKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSD 824
+ A+ E K ++ + ++ +M+ R E E E + + +E+ + +L
Sbjct: 1707 QERAE-EGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHI-HELQELKDQLEQQLQGLHR 1764
Query: 825 RVRELQEQVAELKAEIMRLEAWKSRALGHTEL 856
+V E +++ + EI+ L+ A EL
Sbjct: 1765 KVGETSLLLSQREQEIVVLQQQLQEAREQGEL 1796
Score = 39.9 bits (89), Expect = 0.039
Identities = 49/218 (22%), Positives = 102/218 (46%), Gaps = 18/218 (8%)
Query: 632 LSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV--SDIMATPKKLL--RAWEGRS 687
L L R + + ++ R L + +QE A Q ++ +K R+W +
Sbjct: 813 LELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQE 872
Query: 688 -ADMLK-LDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLREN 745
A L+ L+ E M +R E TE++ ++ + E TQ + + Q++ + E+ R+
Sbjct: 873 LAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERV--SL 930
Query: 746 LDAALQRERALQTRQREFQHKYADLESKAKYESMQANI--RNMEDAQRIAELETEVSEYK 803
L+ LQ ++ L ++ + D++ + E I +++AQR EL+ ++
Sbjct: 931 LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQR--ELKEAARQH- 987
Query: 804 LKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIM 841
++++ A + E + D D LQ+QV +LK++++
Sbjct: 988 -RDDLAALQEESSSLLQDKMD----LQKQVEDLKSQLV 1020
Score = 39.5 bits (88), Expect = 0.052
Identities = 76/370 (20%), Positives = 145/370 (39%), Gaps = 29/370 (7%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSL-EMTIAENNSRQSSLEGTESASGQK 561
E++ L R+V +Q + V +++ E + S QS L+ + A Q+
Sbjct: 1756 EQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815
Query: 562 HEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV-AHLQDEL 620
+EL LQ +++ K + D+ A +E
Sbjct: 1816 DQEL-EALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEE 1874
Query: 621 IAVKLREAEA-NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
+AV+ R +A L DLR E ++ Q+ ++A V++ + D + +
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAV 1934
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEA 739
L+ R ++ L E ++R +E A + L+ + + +Q L Q E +
Sbjct: 1935 LKE---RDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELS 1991
Query: 740 R-------LLRENLDA----ALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMED 788
R L+ +LDA + Q E AL+ ++ E Q + DL + + +Q + ++
Sbjct: 1992 RSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQ--DLRYQEDVQQLQQALAQRDE 2049
Query: 789 AQRIAELETEVSEYKLKNEV---MATEGELRNNNMDDSD------RVRELQEQVAELKAE 839
R + ++ E L V M E + ++ + VRELQ +A+ + E
Sbjct: 2050 ELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQE 2109
Query: 840 IMRLEAWKSR 849
I+ L + R
Sbjct: 2110 ILELRETQQR 2119
Score = 37.5 bits (83), Expect = 0.21
Identities = 36/150 (24%), Positives = 73/150 (48%), Gaps = 9/150 (6%)
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQ 751
KL+E L T + + TEL++L+ ++ + + + + + E L E + +
Sbjct: 1268 KLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQS 1327
Query: 752 RERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMAT 811
R R + ++ E Q + +L AK E++ A + +++ A + E + S + E + T
Sbjct: 1328 RLRRAELQRMEAQGE-RELLQAAK-ENLTAQVEHLQAA--VVEARAQASAAGILEEDLRT 1383
Query: 812 EG---ELRNNNMD-DSDRVRELQEQVAELK 837
+L+N ++ + +R + LQEQ ELK
Sbjct: 1384 ARSALKLKNEEVESERERAQALQEQ-GELK 1412
Score = 36.7 bits (81), Expect = 0.36
Identities = 57/259 (22%), Positives = 112/259 (43%), Gaps = 30/259 (11%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIA-VKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+LE ++ L Q+ + L+D+ K+ E + LR+R EL+ QR L +
Sbjct: 1652 DLERRDQELMLQK--ERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTT--QRQLMQ 1707
Query: 655 HKQEAPAAPVQSNVVSD-----IMATPKKLLRAWEGRSADMLKLDEEL------MTTRIR 703
+ E P ++ S I+ +K + + ++ +L ++L + ++
Sbjct: 1708 ERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVG 1767
Query: 704 EVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRER---ALQTRQ 760
E L +E + V++ + Q +L+ Q +++L E A QR++ ALQ Q
Sbjct: 1768 ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQL-DEAQRALAQRDQELEALQQEQ 1826
Query: 761 REFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM 820
++ Q + ++ KA +M +R EL+ + + E +A EG
Sbjct: 1827 QQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGR------ 1880
Query: 821 DDSDRVRELQEQVAELKAE 839
RV+ L+E + +L+AE
Sbjct: 1881 ----RVQALEEVLGDLRAE 1895
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 53.6 bits (123), Expect = 3e-06
Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 15/253 (5%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+ L +++L D + L +E+ +K + A++N + L V+ E +
Sbjct: 468 VQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQER-----E 522
Query: 654 EHKQEAPAAPVQSNVV-SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+ Q Q VV + K+L+ A E + +L + ++ AL E
Sbjct: 523 DSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKL----ALQEFS 578
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
EL ++ EL Q Q + QLR ++EE + + +DA Q R + ++E + A L+
Sbjct: 579 ELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELE---AQLDD 635
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
S + +R + ++E+E+ K+K G + + S EL+++
Sbjct: 636 AVAEASKERKLREHSE-NFCKQMESELEALKVKQGGRGA-GATLEHQQEISKIKSELEKK 693
Query: 833 VAELKAEIMRLEA 845
V + E++R EA
Sbjct: 694 VLFYEEELVRREA 706
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 53.6 bits (123), Expect = 3e-06
Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 15/253 (5%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+ L +++L D + L +E+ +K + A++N + L V+ E +
Sbjct: 468 VQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQER-----E 522
Query: 654 EHKQEAPAAPVQSNVV-SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+ Q Q VV + K+L+ A E + +L + ++ AL E
Sbjct: 523 DSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKL----ALQEFS 578
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
EL ++ EL Q Q + QLR ++EE + + +DA Q R + ++E + A L+
Sbjct: 579 ELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELE---AQLDD 635
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
S + +R + ++E+E+ K+K G + + S EL+++
Sbjct: 636 AVAEASKERKLREHSE-NFCKQMESELEALKVKQGGRGA-GATLEHQQEISKIKSELEKK 693
Query: 833 VAELKAEIMRLEA 845
V + E++R EA
Sbjct: 694 VLFYEEELVRREA 706
>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
Length = 1943
Score = 53.6 bits (123), Expect = 3e-06
Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 17/271 (6%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
E E + ++R + Q+E + RE L ++ R++ + +R +E ++
Sbjct: 461 EEETERHEQERRKQQLKRDQEE----ERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 658 EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLK 717
+ + + + + ++L R E R +LK +EE + R + L +E R
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 718 VMELETQVQVSTNQLRRQDE---EARLLRENLDAALQ---RERALQTRQREFQHKYADLE 771
+ L+ + + +L+R+ E E RL RE ++ Q RE+ L+ + E + + L+
Sbjct: 577 QL-LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
S+ + E Q +R + +R L+ E E +L+ + E R + + E QE
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR----EQELAEEEQE 691
Query: 832 QVAE-LKAEIMRLEAWKSRALGHTELSRAIS 861
Q E +K+ I + + W+ + S+ S
Sbjct: 692 QARERIKSRIPKWQ-WQLESEADARQSKVYS 721
Score = 53.2 bits (122), Expect = 4e-06
Identities = 64/275 (23%), Positives = 125/275 (45%), Gaps = 22/275 (8%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
+LE E + +++R + + Q+E +L+ E + L+QR+ SE R QE
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEE---ERLQQRLR--SEQQLRREQEE 544
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRI-REVEALTELKEL 714
++E + + ++L R E R +LK +EE R+ RE E E +
Sbjct: 545 RREQLLKREEEKRLEQ-ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD-LESK 773
R +V LE Q + +L+R++ E ++ L + Q ER Q +RE Q + L+ +
Sbjct: 604 REEVERLE-QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 774 AKYESMQANIRNMEDAQR----IAELETEVSEYKLKNEV------MATEGELRNNNMDDS 823
+ E ++ ++ + +R +AE E E + ++K+ + + +E + R + +
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722
Query: 824 DRVRELQEQVAELKAEIMRLEA---WKSRALGHTE 855
R +E Q + E + + R E+ W+ H +
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757
Score = 46.8 bits (106), Expect = 3e-04
Identities = 58/265 (21%), Positives = 111/265 (41%), Gaps = 17/265 (6%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSE---LSESWQRHLQE 654
E E + L RQ D + +L + +E + ++LR + E L E Q H Q+
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQL---RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
+++ + + ++ R + R + L+ + E +E + L+E
Sbjct: 1529 RQRKF--LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
+++ E E + QLRRQ+ + +L +E + E+ LQ R+ + H+ E
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ---ERDR 1643
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDR-VRELQEQV 833
K+ + +R E Q +L + + E + EGE + + DR RE ++Q+
Sbjct: 1644 KFLEEEPQLRRQEREQ---QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Query: 834 AELKAEIMRLEAWKSRALGHTELSR 858
+ E L+ + + L EL R
Sbjct: 1701 RRQERERKFLQ--EEQQLRRQELER 1723
Score = 39.1 bits (87), Expect = 0.068
Identities = 57/257 (22%), Positives = 103/257 (40%), Gaps = 12/257 (4%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
+LE E RRQ+ L + + E + L +D ++R EL Q +
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAE---GEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE 184
Query: 656 KQEAPAAPVQSNVVSDIMATP-KKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
++ A +QS + P ++ LR E +E+ R R+ E +E
Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK 244
Query: 715 RLKVMEL-----ETQVQVSTNQLRRQ-DEEARLLRENLDAALQRERALQTRQREFQHKYA 768
+ E E ++Q Q +R+ EE LR+ L+RER + +Q++ +
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ 304
Query: 769 DLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE 828
L K + E + E +R E + E E +L+ E + ++ R ++
Sbjct: 305 QLRRKQEEERREQQEERREQQER-REQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 829 L-QEQVAELKAEIMRLE 844
L +EQ E + + +R E
Sbjct: 364 LRREQEEERREQQLRRE 380
Score = 37.9 bits (84), Expect = 0.16
Identities = 74/346 (21%), Positives = 126/346 (36%), Gaps = 19/346 (5%)
Query: 493 VRGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
+R + R EEE +RE Q L R Q+R L+E + L + R+ L
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHR-----QERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 553 GTESASG--QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVD 610
E ++ ++L R + D E + LR++R +
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 611 NNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVS 670
++ + + K R E + ++ ++ E + +R QE +Q+
Sbjct: 1570 QQLSRQERDR---KFRLEEQKVRRQEQERKFMEDEQQLRR--QEGQQQLRQER-DRKFRE 1623
Query: 671 DIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR-LKVMELETQVQVST 729
D ++ + + D L+EE ++R E +L+ R K E E +Q
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEE---PQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
Query: 730 NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDA 789
Q R+ E R RE ++ER + Q E Q + +LE K + E E
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 790 QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAE 835
+R + E +L+ E E +LR D R E Q E
Sbjct: 1741 RRQERYRKILEEEQLRPE--REEQQLRRQERDRKFREEEQLRQERE 1784
Score = 36.7 bits (81), Expect = 0.36
Identities = 52/238 (21%), Positives = 101/238 (42%), Gaps = 15/238 (6%)
Query: 605 RRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPV 664
R+ R D + +++L+ + + K R+ EL + ++ L+E +++
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE-EELQQEEEQLLREEREKRRRQEW 1016
Query: 665 --QSNVVSDIMATPKKLLRAW--EGRSADMLKLDEELMTTRIREVEALTELKELRLKVME 720
Q ++ ++LLR + R + + E + E + L E +E R + E
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR-QE 1075
Query: 721 LETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR-----QREFQHKYADLESKAK 775
LE Q + + Q EE +LLRE + ++ER Q R Q+E + + K +
Sbjct: 1076 LERQYR---KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 776 YESMQANIRNMEDAQRIAE-LETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
+ ++ R E+ Q+ E L E E + + E+ E ++ +RE QE+
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK 1190
Score = 36.3 bits (80), Expect = 0.48
Identities = 37/171 (21%), Positives = 71/171 (41%), Gaps = 6/171 (3%)
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEA 739
LR E + + +EE R+R + L +E + + E + Q + + + E
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 740 RLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESM--QANIRNMEDAQRIAELET 797
+L RE + Q+ R Q +R Q + E + + + + + +R + +R +L
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Query: 798 EVS---EYKLKNE-VMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
E E +L+ E + E +LR ++ E EQ E + RL+
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Score = 36.3 bits (80), Expect = 0.48
Identities = 68/339 (20%), Positives = 122/339 (35%), Gaps = 18/339 (5%)
Query: 498 DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESA 557
DR EEE +RE Q L R D + RL + E E+ + EG +
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ-- 1611
Query: 558 SGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQ 617
Q +E R + ++E LRRQ + + H +
Sbjct: 1612 --QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE----EPQLRRQEREQQLRHDR 1665
Query: 618 DELIAVK---LREAEANLSLKDLRQR-VSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
D + L+E E + R R E + +R +E K ++ +
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 674 ATPKKLLRAWEG----RSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVST 729
++L + E R K+ EE RE + L + R E + + +
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 730 NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDA 789
QLR Q+ + + E + E+ L+ +QR+ ++++ E + + E + +R D
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE--EEQLQLEEQEQRLRQERDR 1843
Query: 790 QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE 828
Q AE + E + E + E + + ++RE
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Score = 35.9 bits (79), Expect = 0.64
Identities = 51/248 (20%), Positives = 105/248 (42%), Gaps = 11/248 (4%)
Query: 596 ELENENKSLRR-QRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
EL+ E + LR+ +R + ++E +LR E L K +R + E +R QE
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRR-EQQLRRKQEEERREQQEE--RREQQE 326
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEG-RSADMLKLD--EELMTTRIREVEALTEL 711
+++ Q ++L R E R L+ + EE ++R + L
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 712 KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
++LR + Q QLRR+ + R + + L+RE+ + +++ + + +
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
K + E + ++ E+ +R E E + K E E L+ +++ +R + +
Sbjct: 447 LKREQEERRDWLKREEETER-HEQERRKQQLKRDQEEERRERWLK---LEEEERREQQER 502
Query: 832 QVAELKAE 839
+ +L+ E
Sbjct: 503 REQQLRRE 510
Score = 35.5 bits (78), Expect = 0.84
Identities = 51/251 (20%), Positives = 108/251 (43%), Gaps = 19/251 (7%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQ--RHL 652
+E E + RR++ + Q+E +LR + + LR+ E Q R
Sbjct: 311 EEERREQQEERREQQERR--EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 653 QEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRI--REVEALTE 710
+E ++E Q + ++L R + R L+ +++L + RE + E
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEAR--LLRENLDAALQRERALQTRQREFQH--- 765
+E R E + + + +L+R+ EE R L RE ++ER Q +R+ +
Sbjct: 429 QEEER---HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 766 ----KYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
K + E + + E + +R ++ +R L+ + E +L+ + +E +LR +
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR-LRSEQQLRREQEE 544
Query: 822 DSDRVRELQEQ 832
+++ + +E+
Sbjct: 545 RREQLLKREEE 555
Score = 35.5 bits (78), Expect = 0.84
Identities = 53/249 (21%), Positives = 95/249 (38%), Gaps = 15/249 (6%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
E E + ++ RR R L E K R E + ++ Q + E E R QE
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR-QER 1358
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT-RIREVEALTELK-- 712
++ ++ ++ LR E R LK +++L R +++ + K
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQE-RERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 713 --ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQR-------ERALQTRQREF 763
E +L E + + + Q+RRQ+ E + L E +R E+ LQ R+ +
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Query: 764 QHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS 823
H+ + + K E Q + + R EL ++ E K E + R
Sbjct: 1478 LHR-QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
Query: 824 DRVRELQEQ 832
++ QE+
Sbjct: 1537 EQQLRRQER 1545
Score = 35.1 bits (77), Expect = 1.1
Identities = 59/277 (21%), Positives = 120/277 (43%), Gaps = 31/277 (11%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELI------AVKLREAEANLSLKDLRQRVSEL--SE 646
+E E E + +R+ + + L++E A +L+E E L R+R E +
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Query: 647 SWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
W+ L+E ++ + + + ++LL+ E + L+ +E R +
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE----EELQREEREKRRRQEQER 928
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERAL-----QTRQR 761
E ++L+ + E Q+ + RR+ E R R++ + E+ L + R++
Sbjct: 929 QYREEEQLQQE----EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + KY + E + + E Q +R + +R E E +Y+ K+E+ E +L +
Sbjct: 985 EREKKYRE-EEELQQEEEQL-LREEREKRRRQEWE---RQYRKKDELQQEEEQL----LR 1035
Query: 822 DSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSR 858
+ R LQE+ + + E L+ + + LG +R
Sbjct: 1036 EEREKRRLQERERQYREE-EELQQEEEQLLGEERETR 1071
Score = 33.9 bits (74), Expect = 2.6
Identities = 37/220 (16%), Positives = 91/220 (41%), Gaps = 6/220 (2%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELI-AVKLREAEANLSLKDLRQRVSELSESWQRHLQEHK 656
E E + +++ + H +E +LR E L +LR++ E + +R Q+
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRE----LLELRRKGREEKQQQRRERQDRV 237
Query: 657 QEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL 716
+ + + +KL R ++ + +E+L +E+ + +E +
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
+ + E Q++ + RR+ +E R ++ + R Q R+ + + + L + +
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELR 816
E + +R ++ +R E + + + + + E +LR
Sbjct: 358 ERREQQLRREQEEER-REQQLRREQQLRREQQLRREQQLR 396
Score = 33.1 bits (72), Expect = 4.5
Identities = 64/340 (18%), Positives = 123/340 (36%), Gaps = 12/340 (3%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
R + E L RE + R + Q+ +RS + E R+ L E
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
+ E + L+ ++ E + L+R+ V+ Q+
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE---QE 613
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
E +L+ E + + E E Q+ L+ +QE ++ + + K
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK 673
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELK---ELRLKVMELETQVQVSTNQLRRQ 735
E R ++ + ++E RI+ + + E + ++ ++ + Q RRQ
Sbjct: 674 REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQ 733
Query: 736 D-EEARLLRENLDAALQRERALQTRQREFQHK----YADLESKAKYESMQANIRNMEDAQ 790
+ EE R RE+ + ERA + +Q E Q + E K++ + + R Q
Sbjct: 734 EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQ 830
R +L E + + + + E E +R +ELQ
Sbjct: 794 RERQLRAEERQQR-EQRFLPEEEEKEQRRRQRREREKELQ 832
Score = 32.3 bits (70), Expect = 7.8
Identities = 47/241 (19%), Positives = 95/241 (39%), Gaps = 14/241 (5%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
E + E + +R R + + Q+E + + E ++ R++ E E R QE
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEE---ERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEG-RSADMLKLDEELMTTRIREVEALTELKEL 714
++E Q + ++L R E R L+ +++L RE + E +
Sbjct: 346 RREQQLRREQEEERRE-----QQLRREQEEERREQQLRREQQLR----REQQLRREQQLR 396
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
R + + E Q++ QLRR+ + R + + +R ++R Q + E +
Sbjct: 397 REQQLRREQQLR-REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ + E +R +L+ + E + + + E E R ++R QE+
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 835 E 835
E
Sbjct: 516 E 516
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 53.6 bits (123), Expect = 3e-06
Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 15/253 (5%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+ L +++L D + L +E+ +K + A++N + L V+ E +
Sbjct: 468 VQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQER-----E 522
Query: 654 EHKQEAPAAPVQSNVV-SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+ Q Q VV + K+L+ A E + +L + ++ AL E
Sbjct: 523 DSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKL----ALQEFS 578
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
EL ++ EL Q Q + QLR ++EE + + +DA Q R + ++E + A L+
Sbjct: 579 ELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELE---AQLDD 635
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
S + +R + ++E+E+ K+K G + + S EL+++
Sbjct: 636 AVAEASKERKLREHSE-NFCKQMESELEALKVKQGGRGA-GATLEHQQEISKIKSELEKK 693
Query: 833 VAELKAEIMRLEA 845
V + E++R EA
Sbjct: 694 VLFYEEELVRREA 706
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 53.6 bits (123), Expect = 3e-06
Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 15/253 (5%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+ L +++L D + L +E+ +K + A++N + L V+ E +
Sbjct: 517 VQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQER-----E 571
Query: 654 EHKQEAPAAPVQSNVV-SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+ Q Q VV + K+L+ A E + +L + ++ AL E
Sbjct: 572 DSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKL----ALQEFS 627
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
EL ++ EL Q Q + QLR ++EE + + +DA Q R + ++E + A L+
Sbjct: 628 ELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELE---AQLDD 684
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
S + +R + ++E+E+ K+K G + + S EL+++
Sbjct: 685 AVAEASKERKLREHSE-NFCKQMESELEALKVKQGGRGA-GATLEHQQEISKIKSELEKK 742
Query: 833 VAELKAEIMRLEA 845
V + E++R EA
Sbjct: 743 VLFYEEELVRREA 755
>BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein.
Length = 1236
Score = 53.2 bits (122), Expect = 4e-06
Identities = 73/350 (20%), Positives = 155/350 (44%), Gaps = 30/350 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSR--QSSLEGTESASGQ 560
EEE A ++E+ ALR NV +Q+++A + S + E + + L S
Sbjct: 206 EEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTD 265
Query: 561 KHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDEL 620
+ ++ LQ + E+E E ++ R+ + + + +
Sbjct: 266 ETSQIVE-LQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQR 324
Query: 621 IAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLL 680
+REA A +D+ +R++ L +R+L ++ + + ++ +A + +L
Sbjct: 325 ---DIREAMA--QKEDMEERITTLE---KRYLSAQRESTSIHDMNDKLENE-LANKEAIL 375
Query: 681 RAWEGRSADM---LKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQVSTN-QLRRQ 735
R E ++ + L+L E+ + +R+ E L E++ EL ++ L + N + R +
Sbjct: 376 RQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMR 435
Query: 736 DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAEL 795
E +L +N + LQR R + E + +D + ES + +++ +R+A L
Sbjct: 436 HLEGQLEEKNQE--LQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLK--ERMAAL 491
Query: 796 ETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLE 844
E + V+ E E N+++S +E L E++ +L++E+ +L+
Sbjct: 492 E--------EKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLK 533
>AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein
protein.
Length = 1258
Score = 53.2 bits (122), Expect = 4e-06
Identities = 73/350 (20%), Positives = 155/350 (44%), Gaps = 30/350 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSR--QSSLEGTESASGQ 560
EEE A ++E+ ALR NV +Q+++A + S + E + + L S
Sbjct: 217 EEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTD 276
Query: 561 KHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDEL 620
+ ++ LQ + E+E E ++ R+ + + + +
Sbjct: 277 ETSQIVE-LQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQR 335
Query: 621 IAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLL 680
+REA A +D+ +R++ L +R+L ++ + + ++ +A + +L
Sbjct: 336 ---DIREAMA--QKEDMEERITTLE---KRYLSAQRESTSIHDMNDKLENE-LANKEAIL 386
Query: 681 RAWEGRSADM---LKLDEELMTTRIREVEALTELK-ELRLKVMELETQVQVSTN-QLRRQ 735
R E ++ + L+L E+ + +R+ E L E++ EL ++ L + N + R +
Sbjct: 387 RQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMR 446
Query: 736 DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAEL 795
E +L +N + LQR R + E + +D + ES + +++ +R+A L
Sbjct: 447 HLEGQLEEKNQE--LQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLK--ERMAAL 502
Query: 796 ETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQVAELKAEIMRLE 844
E + V+ E E N+++S +E L E++ +L++E+ +L+
Sbjct: 503 E--------EKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLK 544
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 52.8 bits (121), Expect = 5e-06
Identities = 84/380 (22%), Positives = 156/380 (41%), Gaps = 28/380 (7%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVAL----DEIRSLEMTIAENNSRQSSL 551
Q R E ++ L++E LRR NV++Q + A ++ L + + E Q L
Sbjct: 469 QKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEML 528
Query: 552 EGTESASGQKHEELARCLQXXXXX------XXXXXXXXXXXXXXXXXXIDELENENKSLR 605
G E+ + EL + I EL + +L+
Sbjct: 529 MGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 588
Query: 606 RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQ 665
+ D A + +L A L EA A L L Q++ +L E Q + EA A +
Sbjct: 589 TEVADLRAAAV--KLSA--LNEALA-LDKVGLNQQLLQLEEENQSVCS--RMEA-AEQAR 640
Query: 666 SNVVSDIMATPKKLLRAWEGRS---ADMLKLDEELMTTRIREVEALTELKELRLKVMELE 722
+ + D+ K+ WE + A + K +E + + E +E++ K+ E
Sbjct: 641 NALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESR 700
Query: 723 TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN 782
Q + +T QL + +EA+ E L A+Q + AL + + + +E + +
Sbjct: 701 HQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDR--QDLAEQ 758
Query: 783 IRNMEDAQRIAELETEVSEYKLKNEVM-ATEGELRNNNMDDSDRVRELQEQVAELKAEI- 840
++ + A+ + LE+ + E + +N V+ T+G+L + +Q +V LK E+
Sbjct: 759 LQGLSSAKEL--LESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELD 816
Query: 841 -MRLEAWKSRALGHTELSRA 859
R +A + R +L++A
Sbjct: 817 TERSQAEQERDAAARQLAQA 836
Score = 47.2 bits (107), Expect = 3e-04
Identities = 66/332 (19%), Positives = 142/332 (42%), Gaps = 25/332 (7%)
Query: 512 EVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQX 571
+VQ L D + + E++ L+ +++N +S EG +++ + EL +
Sbjct: 1265 QVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMAS 1324
Query: 572 XXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEAN 631
E E ++ + V HLQ ++ + + + A
Sbjct: 1325 LQSRLRRAELQRMEAQG---------ERELLQAAKENLTAQVEHLQAAVVEARAQASAAG 1375
Query: 632 LSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADML 691
+ +DLR S L ++ ++ A A Q + +A K L + +
Sbjct: 1376 ILEEDLRTARSALKLK-NEEVESERERAQALQEQGELK---VAQGKALQENLALLTQTLA 1431
Query: 692 KLDEELMTTR--IREVEALTELKELRLKVMELETQ---VQVSTNQLRRQD-EEARLLREN 745
+ +EE+ T R I+E+E E+++ L+++ L+ + +V Q + Q+ E+ R + E+
Sbjct: 1432 EREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEH 1491
Query: 746 LDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELET-EVSEYK- 803
L A+Q T QRE Q + + + + + ++ + +E ++ E + +V + K
Sbjct: 1492 LPMAVQEREQKLTVQRE-QIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKK 1550
Query: 804 --LKNEVMATEGELRNNNMDDSDR-VRELQEQ 832
+ E +A E E ++ M+ + ++EL+ Q
Sbjct: 1551 QLVTLECLALELEENHHKMECQQKLIKELEGQ 1582
Score = 45.6 bits (103), Expect = 8e-04
Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 15/246 (6%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
E E +Q+ ++++ A++ +A+++LK+ + + E +R +E
Sbjct: 1818 ELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAV 1877
Query: 658 EAPAAPVQSNVVSDIMATPK---KLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
E V+ D+ A + K L A + + A+ + E + TR + L L
Sbjct: 1878 EGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQ--EHEVETRALQDSWLQAQAVL 1935
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
+ + ELE ++ + R Q+E AR E L AL + A Q + QH E
Sbjct: 1936 KERDQELEA-LRAESQSSRHQEEAARARAEALQEALGKAHA--ALQGKEQHLLEQAELSR 1992
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
E+ A ++ DA + +L+ + EGE+++ ++ + V++LQ+ +A
Sbjct: 1993 SLEASTATLQASLDA-------CQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALA 2045
Query: 835 ELKAEI 840
+ E+
Sbjct: 2046 QRDEEL 2051
Score = 42.3 bits (95), Expect = 0.007
Identities = 54/255 (21%), Positives = 107/255 (41%), Gaps = 19/255 (7%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+++E E + L+ Q+ + Q E + A + L+ ++RVS L + LQ
Sbjct: 883 EKMELEMR-LKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLL----ETLLQT 937
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE- 713
K+ A A+ + D+ K + + EL + + L L+E
Sbjct: 938 QKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 997
Query: 714 ---LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADL 770
L M+L+ QV+ +QL QD+ RL+ + + L+ + Q+E + + A L
Sbjct: 998 SSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASL 1057
Query: 771 ESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQ 830
+ + + D+ R EL L+ ++ +GE + + S ++ L+
Sbjct: 1058 TLSLMEKEQRLLVLQEADSIRQQELSA------LRQDMQEAQGEQK----ELSAQMELLR 1107
Query: 831 EQVAELKAEIMRLEA 845
++V E +A+ + EA
Sbjct: 1108 QEVKEKEADFLAQEA 1122
Score = 40.7 bits (91), Expect = 0.022
Identities = 59/272 (21%), Positives = 120/272 (44%), Gaps = 16/272 (5%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLR--EAEANLSLKDLRQR-VSELS--ESWQR 650
ELE +++ + QR V L+ +L+ ++ E E N + +Q+ + EL QR
Sbjct: 1530 ELEKKDQMIESQR--GQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQR 1587
Query: 651 HLQEH-----KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV 705
H ++ + QS+ + D+ + L R + R ++ E++ + R+
Sbjct: 1588 VALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQ-RQK 1646
Query: 706 EALTELKELRLKVMELETQ-VQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQ 764
E LT+ E R + + L+ + +QV +Q RQ + E + +L+ T QR+
Sbjct: 1647 EHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLM 1706
Query: 765 HKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSD 824
+ A+ E K ++ + ++ +M+ R E E E + + +E+ + +L
Sbjct: 1707 QERAE-EGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHI-HELQELKDQLEQQLQGLHR 1764
Query: 825 RVRELQEQVAELKAEIMRLEAWKSRALGHTEL 856
+V E +++ + EI+ L+ A EL
Sbjct: 1765 KVGETSLLLSQREQEIVVLQQQLQEAREQGEL 1796
Score = 39.9 bits (89), Expect = 0.039
Identities = 49/218 (22%), Positives = 102/218 (46%), Gaps = 18/218 (8%)
Query: 632 LSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV--SDIMATPKKLL--RAWEGRS 687
L L R + + ++ R L + +QE A Q ++ +K R+W +
Sbjct: 813 LELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQE 872
Query: 688 -ADMLK-LDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLREN 745
A L+ L+ E M +R E TE++ ++ + E TQ + + Q++ + E+ R+
Sbjct: 873 LAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERV--SL 930
Query: 746 LDAALQRERALQTRQREFQHKYADLESKAKYESMQANI--RNMEDAQRIAELETEVSEYK 803
L+ LQ ++ L ++ + D++ + E I +++AQR EL+ ++
Sbjct: 931 LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQR--ELKEAARQH- 987
Query: 804 LKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIM 841
++++ A + E + D D LQ+QV +LK++++
Sbjct: 988 -RDDLAALQEESSSLLQDKMD----LQKQVEDLKSQLV 1020
Score = 39.5 bits (88), Expect = 0.052
Identities = 76/370 (20%), Positives = 145/370 (39%), Gaps = 29/370 (7%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSL-EMTIAENNSRQSSLEGTESASGQK 561
E++ L R+V +Q + V +++ E + S QS L+ + A Q+
Sbjct: 1756 EQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815
Query: 562 HEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV-AHLQDEL 620
+EL LQ +++ K + D+ A +E
Sbjct: 1816 DQEL-EALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEE 1874
Query: 621 IAVKLREAEA-NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
+AV+ R +A L DLR E ++ Q+ ++A V++ + D + +
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAV 1934
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEA 739
L+ R ++ L E ++R +E A + L+ + + +Q L Q E +
Sbjct: 1935 LKE---RDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELS 1991
Query: 740 R-------LLRENLDA----ALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMED 788
R L+ +LDA + Q E AL+ ++ E Q + DL + + +Q + ++
Sbjct: 1992 RSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQ--DLRYQEDVQQLQQALAQRDE 2049
Query: 789 AQRIAELETEVSEYKLKNEV---MATEGELRNNNMDDSD------RVRELQEQVAELKAE 839
R + ++ E L V M E + ++ + VRELQ +A+ + E
Sbjct: 2050 ELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQE 2109
Query: 840 IMRLEAWKSR 849
I+ L + R
Sbjct: 2110 ILELRETQQR 2119
Score = 37.5 bits (83), Expect = 0.21
Identities = 36/150 (24%), Positives = 73/150 (48%), Gaps = 9/150 (6%)
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQ 751
KL+E L T + + TEL++L+ ++ + + + + + E L E + +
Sbjct: 1268 KLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQS 1327
Query: 752 RERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMAT 811
R R + ++ E Q + +L AK E++ A + +++ A + E + S + E + T
Sbjct: 1328 RLRRAELQRMEAQGE-RELLQAAK-ENLTAQVEHLQAA--VVEARAQASAAGILEEDLRT 1383
Query: 812 EG---ELRNNNMD-DSDRVRELQEQVAELK 837
+L+N ++ + +R + LQEQ ELK
Sbjct: 1384 ARSALKLKNEEVESERERAQALQEQ-GELK 1412
Score = 36.7 bits (81), Expect = 0.36
Identities = 57/259 (22%), Positives = 112/259 (43%), Gaps = 30/259 (11%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIA-VKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+LE ++ L Q+ + L+D+ K+ E + LR+R EL+ QR L +
Sbjct: 1652 DLERRDQELMLQK--ERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTT--QRQLMQ 1707
Query: 655 HKQEAPAAPVQSNVVSD-----IMATPKKLLRAWEGRSADMLKLDEEL------MTTRIR 703
+ E P ++ S I+ +K + + ++ +L ++L + ++
Sbjct: 1708 ERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVG 1767
Query: 704 EVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRER---ALQTRQ 760
E L +E + V++ + Q +L+ Q +++L E A QR++ ALQ Q
Sbjct: 1768 ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQL-DEAQRALAQRDQELEALQQEQ 1826
Query: 761 REFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM 820
++ Q + ++ KA +M +R EL+ + + E +A EG
Sbjct: 1827 QQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGR------ 1880
Query: 821 DDSDRVRELQEQVAELKAE 839
RV+ L+E + +L+AE
Sbjct: 1881 ----RVQALEEVLGDLRAE 1895
>AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein
protein.
Length = 590
Score = 52.8 bits (121), Expect = 5e-06
Identities = 74/366 (20%), Positives = 157/366 (42%), Gaps = 34/366 (9%)
Query: 503 EEETFALDRE-----VQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESA 557
E+E F L ++ + L NV + + + + + +S I E +R L G
Sbjct: 2 EQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGEAEN 61
Query: 558 SG-------QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLR-RQRV 609
S Q+ EL RC Q +++ E K L+ +
Sbjct: 62 SNLQRQKLIQEKAELERCYQITSSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDA 121
Query: 610 DNNVAHLQDELIAVK----LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQ 665
D N+ + L A K + E E N+ + + SEL Q QE+K + + ++
Sbjct: 122 DINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLK 181
Query: 666 SNVVSDIMATPKKLLRAWEGRSADMLKLDEEL-----MTTRIREVEALTELKELRLKVME 720
+L + E + K +E L TR+ EV+ L + ++ + E
Sbjct: 182 HIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRL-QAQQADAALEE 240
Query: 721 LETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ-REFQHKYADLESKAKYESM 779
+ QV++++ ++ E + E ++A L R ++L+ +Q +EF + D+ + + + +
Sbjct: 241 FKRQVELNSEKVYA---EMKKQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIV 297
Query: 780 QANIRNMEDA-----QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
+ + + ++ Q AE ++ V +++ E+ E +LR NM+ ++++E +++ A
Sbjct: 298 ELKLEHEQEKTHLLQQHNAEKDSLVRDHE--REIENLEKQLRAANMEHENQIQEFKKRDA 355
Query: 835 ELKAEI 840
++ A++
Sbjct: 356 QVIADM 361
Score = 40.7 bits (91), Expect = 0.022
Identities = 58/280 (20%), Positives = 128/280 (45%), Gaps = 23/280 (8%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLREAE-------ANLSLKDLRQRVSELS-ESW 648
+E E L++Q +N L+D + + E+E N +K+L RV +L+ E+
Sbjct: 1 MEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGEAE 60
Query: 649 QRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEAL 708
+LQ K A ++ I ++ + ++A R + K + L+ + ++ L
Sbjct: 61 NSNLQRQKLIQEKAELER--CYQITSSELQEVKA---RRNTLHKEKDHLVNDYEQNMKLL 115
Query: 709 TELKELRLKVMELETQVQVS--TNQLRRQDEEARLLRENL-DAALQRERALQTRQREFQH 765
+ + +++ E + S ++ + ++ L++ L ++ LQR++ L+ ++ +FQ
Sbjct: 116 QTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQM 175
Query: 766 KYADLES--KAKYESMQANI-RNMEDAQ-RIAELETEVSEYKLKNEVMATEGELRNNNMD 821
+ + L+ + K +Q+ + + ED Q +I + E + E K E + E++
Sbjct: 176 EKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKE---KEEQLTRVTEVQRLQAQ 232
Query: 822 DSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSRAIS 861
+D E ++ EL +E + E K +L+R+ S
Sbjct: 233 QADAALEEFKRQVELNSEKVYAEMKKQMEKVEADLTRSKS 272
Score = 39.1 bits (87), Expect = 0.068
Identities = 50/237 (21%), Positives = 104/237 (43%), Gaps = 28/237 (11%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
+LE+ + +Q V+ + H Q++ ++ AE + ++D + + L + + EH
Sbjct: 284 QLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEH 343
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+ N + + +++ E A + KL EEL+ + + L EL LR
Sbjct: 344 E----------NQIQEFKKRDAQVIADME---AQVHKLREELINVNSQRKQQLVELGLLR 390
Query: 716 LKVMELETQV-QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
+ + T+ ++ N+L+ + E+ ++ + AA + E L+ SK
Sbjct: 391 EEEKQRATREHEIVVNKLKAESEKMKIELKKTHAA-ETEMTLEKAN-----------SKL 438
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKN--EVMATEGELRNNNMDDSDRVREL 829
K + + + +Q IAEL+T +S K +N + +A E L++ D ++L
Sbjct: 439 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 495
Score = 38.7 bits (86), Expect = 0.090
Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 23/207 (11%)
Query: 634 LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKL 693
L+D+RQR + + EH+QE Q N D L+R E ++ L
Sbjct: 285 LEDIRQRYEQQIVELKL---EHEQEKTHLLQQHNAEKD------SLVRDHE---REIENL 332
Query: 694 DEELMTTRIREVEALTELKELRLKVM-ELETQVQVSTNQLRRQDEEARLLRENLDAALQR 752
+++L + + E K+ +V+ ++E QV +L + + + ++ ++ L R
Sbjct: 333 EKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRK--QQLVELGLLR 390
Query: 753 ERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATE 812
E Q RE H+ + KA+ E M+ ++ A ETE++ K +++ E
Sbjct: 391 EEEKQRATRE--HEIVVNKLKAESEKMKIELKKTHAA------ETEMTLEKANSKLKQIE 442
Query: 813 GELRNNNMDDSDRVRELQEQVAELKAE 839
E S + ELQ ++ LK E
Sbjct: 443 KEYTQKLAKSSQIIAELQTTISSLKEE 469
Score = 33.9 bits (74), Expect = 2.6
Identities = 48/220 (21%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL-SESWQRHL 652
I ++E + LR + ++ N Q + LRE E + ++ V++L +ES + +
Sbjct: 358 IADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKI 417
Query: 653 QEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+ K A + + + K++ + + + A ++ EL TT ++ LK
Sbjct: 418 ELKKTHAAETEMTLEKANSKL---KQIEKEYTQKLAKSSQIIAELQTT-------ISSLK 467
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDA--ALQRE---RALQTR--QREFQH 765
E + +L + ++ + + +DE+ +L+R+N A LQ E R+ Q R +++ QH
Sbjct: 468 EENSQ-QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQH 526
Query: 766 KYADLESKAKY--ESMQANIRNMEDAQRIAELETEVSEYK 803
K + + + Y + + ++ + A ELE +S K
Sbjct: 527 KELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLK 566
>AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ36144 fis, clone TESTI2025022, weakly similar to
TRICHOHYALIN. ).
Length = 650
Score = 52.4 bits (120), Expect = 7e-06
Identities = 59/260 (22%), Positives = 120/260 (46%), Gaps = 17/260 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSE----LSESWQRHL 652
LE ++ + + A LQ++L + ++E L++K+L++++ L + L
Sbjct: 211 LELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTL 270
Query: 653 QEH--KQEAPAAPVQSNV--VSDIMATPKKLLRAWEGRSADM-LKLDEELMTTRIREVEA 707
QE +QE + + + M ++ LR EG+ + K+ + R +E E
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 708 LTELKELR--LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
+ KELR K+ E E Q+Q ++ Q+E+ R E + +R + + RE +
Sbjct: 331 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 766 KYADLESK--AKYESMQANIRNMEDAQRIAE-LETEVSEYKLKNEVMATEGELRNNNMDD 822
K D E + + E ++ M + +++ E +E E K++ + T + M +
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ--EEKMQE 448
Query: 823 SDRVRELQEQVAELKAEIMR 842
+R+RE ++++ E + E MR
Sbjct: 449 EERIREREKKMRE-EEETMR 467
Score = 43.6 bits (98), Expect = 0.003
Identities = 54/240 (22%), Positives = 108/240 (45%), Gaps = 19/240 (7%)
Query: 616 LQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHL---QEHKQE----APAAPVQSNV 668
LQ L AV R +A+ +++L + LS R+ +E K++ P+ +
Sbjct: 181 LQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESE 240
Query: 669 VSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVS 728
S+I K+L R E R+ +L ++ T ++E E + +ELR + ++ Q +
Sbjct: 241 KSEIQLNVKELKRKLE-RAKFLLP---QVQTNTLQE-EMWRQEEELREQEKKIRKQEEKM 295
Query: 729 TNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMED 788
Q R E+ +RE + ++E+ L+ +++E + + +L + K + ++ E+
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 355
Query: 789 ---AQRIAELETEVSEYKLKNEVMATEGELRNNNM---DDSDRVRELQEQVAELKAEIMR 842
Q E E ++ + + E ++R D +R+ E E++ E K E MR
Sbjct: 356 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE-KEERMR 414
Score = 39.9 bits (89), Expect = 0.039
Identities = 49/263 (18%), Positives = 110/263 (41%), Gaps = 15/263 (5%)
Query: 596 ELENENKSLRR--QRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
E++ K L+R +R + +Q + ++ E L ++ + R E + W++ +
Sbjct: 243 EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE-EKMWRQEER 301
Query: 654 EHKQEAPAAPVQSNV--VSDIMATPKKLLRAWEGRSADMLKL---DEELMTTRIREVEAL 708
+QE + + + +K LR E + KL +E++ + E
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 361
Query: 709 TELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYA 768
+++E K+ E ++ Q+R Q+++ R E + +R R + R RE + +
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 769 DLESKAKYESMQANIRN-------MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
+E + + MQ + M++ +RI E E ++ E + + + + NM
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Query: 822 DSDRVRELQEQVAELKAEIMRLE 844
+ + Q+++ E K ++ E
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQE 504
Score = 32.7 bits (71), Expect = 5.9
Identities = 39/226 (17%), Positives = 91/226 (40%), Gaps = 10/226 (4%)
Query: 624 KLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW 683
+LRE E L ++ R + + +QE +++ + + M ++ R W
Sbjct: 322 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE--RLW 379
Query: 684 EGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELET---QVQVSTNQLRRQDEEAR 740
E + M + ++++ R E L+E ++ E E QV+ + + Q++E +
Sbjct: 380 E-QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 741 LLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVS 800
+ + +Q E ++ R+++ + + + + E MQ NM + + + +
Sbjct: 439 T--RDQEEKMQEEERIREREKKMREEEETMREQE--EKMQKQEENMWEQEEKEWQQQRLP 494
Query: 801 EYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAW 846
E K K E + +++R+ +E + K + W
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWQEEKMW 540
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 52.0 bits (119), Expect = 9e-06
Identities = 68/362 (18%), Positives = 158/362 (43%), Gaps = 28/362 (7%)
Query: 493 VRGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRS--LEMTIAENNSRQSS 550
++ Q + E+E L + L++++ ++++ E++ L+ T EN +Q
Sbjct: 941 IQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQL 1000
Query: 551 LEGTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVD 610
+ + + +K E LQ + + KS V+
Sbjct: 1001 TQAAQELAAEK--EKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKS-----VE 1053
Query: 611 NNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL---SESWQRHLQEHKQEAPAAPVQSN 667
++ Q++LI+ + + N +++L+ + L S ++ LQE + + +
Sbjct: 1054 EKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKS 1113
Query: 668 VVSDIMATPKKLLRAWEG----RSADMLKLDEELMTTRIREVEALTELKELRLKVMELET 723
+ + K L E + ++ KL+EEL + ++ ++ +T LK+ + +++ +
Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKL 1173
Query: 724 QVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANI 783
++Q + L+ E+ + ++ L +++E + ++EF K A L S+ K + +
Sbjct: 1174 ELQGKADSLKAAVEQEKRNQQILKDQVKKEE--EELKKEFIEKEAKLHSEIK--EKEVGM 1229
Query: 784 RNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
+ E+ + A+L +++ NE + G ++ RV EL++Q +L+ EI L
Sbjct: 1230 KKHEENE--AKLTMQITAL---NENL---GTVKKEWQSSQRRVSELEKQTDDLRGEIAVL 1281
Query: 844 EA 845
EA
Sbjct: 1282 EA 1283
Score = 46.8 bits (106), Expect = 3e-04
Identities = 50/262 (19%), Positives = 120/262 (45%), Gaps = 17/262 (6%)
Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEA 659
+N +L R+R L+DE ++ + A + ++ LR +++ + ++QE ++
Sbjct: 238 DNMTLERERESEK---LKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQK-- 292
Query: 660 PAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVM 719
++S+V +++ + L + D KL+E+ + + L + L
Sbjct: 293 ----LKSSV-NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQ 347
Query: 720 ELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESM 779
+L++++ S L R E L E +A + + L + ++QH A+ + + + +
Sbjct: 348 QLQSRLSASETSLHRIHVE---LSEKGEATQKLKEELSEVETKYQHLKAEFK-QLQQQRE 403
Query: 780 QANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
+ ++ I +L +++ E + ++ G L+ S+++ + ++QVA+L+ +
Sbjct: 404 EKEQHGLQLQSEINQLHSKLLE--TERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLK 461
Query: 840 IMRL-EAWKSRALGHTELSRAI 860
+ RL E K + TEL +
Sbjct: 462 LSRLEEQLKEKVTNSTELQHQL 483
Score = 43.2 bits (97), Expect = 0.004
Identities = 86/442 (19%), Positives = 180/442 (40%), Gaps = 57/442 (12%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQ---GDIA 462
D+E +L+ I + DQ NL ++ + + + LEKE + K Q G+ A
Sbjct: 510 DLEQVLRQI-------GDKDQK-IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETA 561
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRRANVD 522
VL L+++N L+++V ++ Q + + +E L +VQ +
Sbjct: 562 VLNQLQEKNHTLQEQVTQLTEK--------LKNQSESHKQAQEN--LHDQVQ-------E 604
Query: 523 MQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXX 582
+ L A D + SLE ++ E NS+ + S +K +L ++
Sbjct: 605 QKAHLRAAQDRVLSLETSVNELNSQLNE-------SKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 583 XXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVS 642
+D +N +L+ ++ + N Q + + KL++ + + S Q S
Sbjct: 658 KTAQRADLQNHLDTAQN---ALQDKQQELNKITTQLDQVTAKLQDKQEHCS-----QLES 709
Query: 643 ELSESWQRHLQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTR 701
L E +++L E K E ++ + K + + L D EL T
Sbjct: 710 HLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATE 769
Query: 702 I-REVEALTEL-KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ +++E E+ RL + + ++ +L +Q+EE ++L+++ + Q
Sbjct: 770 LSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQ-------- 821
Query: 760 QREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY-KLKNEVMATEGELRNN 818
+ + QH+ +L ++ + + ME + EL T + K+ + + ++ E
Sbjct: 822 ETKIQHE--ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKE 879
Query: 819 NMDDSDRVRELQEQVAELKAEI 840
N + +L++ ELK ++
Sbjct: 880 NQKGKAAILDLEKTCKELKHQL 901
Score = 37.9 bits (84), Expect = 0.16
Identities = 33/158 (20%), Positives = 75/158 (47%), Gaps = 5/158 (3%)
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQ 751
KL+ + + + + +AL +L++ R +LE + + QL + E R +L +
Sbjct: 734 KLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSE 793
Query: 752 RERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMAT 811
+++ + + + + L+ + S + I++ E RI TE+ + K++ E + T
Sbjct: 794 ALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMT 853
Query: 812 E-GELRNNNMDDSDRVR----ELQEQVAELKAEIMRLE 844
E +++ SD ++ E +++ + KA I+ LE
Sbjct: 854 ELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLE 891
Score = 37.5 bits (83), Expect = 0.21
Identities = 53/269 (19%), Positives = 122/269 (45%), Gaps = 31/269 (11%)
Query: 602 KSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQ------RHLQEH 655
K L Q++ + ++ + L + + +E + + L++ +SE+ +Q + LQ+
Sbjct: 342 KDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQ 401
Query: 656 KQEAPAAPVQ-----SNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVE---- 706
++E +Q + + S ++ T ++L A GR + +L E + + ++V
Sbjct: 402 REEKEQHGLQLQSEINQLHSKLLETERQLGEA-HGRLKEQRQLSSEKLMDKEQQVADLQL 460
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQR-ERALQTRQREFQH 765
L+ L+E + + T++Q ++ ++Q +E + L+++ A L+ + L+ R+
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGD 520
Query: 766 KYADLES-KAKYESMQANIRNMEDAQ-------RIAELETEV------SEYKLKNEVMAT 811
K +++ +A + + NI +E + + E ET V + L+ +V
Sbjct: 521 KDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQL 580
Query: 812 EGELRNNNMDDSDRVRELQEQVAELKAEI 840
+L+N + L +QV E KA +
Sbjct: 581 TEKLKNQSESHKQAQENLHDQVQEQKAHL 609
Score = 37.5 bits (83), Expect = 0.21
Identities = 83/439 (18%), Positives = 186/439 (42%), Gaps = 45/439 (10%)
Query: 441 KKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRA 500
K+ ++L E + K ++ D+ L+ R E +L K++V ++ Q+D+
Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQ-LKLSRLEEQL-KEKVTNSTE---------LQHQLDKT 486
Query: 501 EGE-EETFALDREVQA-LRRANVDMQQRLAVALDE---IRSLEMTIAENNSRQSSLEGTE 555
+ + +E AL + A LR A D++Q L D+ I++LE + ++ S LE
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKER 546
Query: 556 S---ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
A Q E L + + ++L Q V
Sbjct: 547 EDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQ-VQEQ 605
Query: 613 VAHL---QDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
AHL QD +++++ E N L + +++VS+L + + A Q +
Sbjct: 606 KAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADL 665
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEEL--MTTRIREVEAL-----TELKELRLKVMELE 722
+ + T + L + + ++ K+ +L +T ++++ + + LKE + K + LE
Sbjct: 666 QNHLDTAQNAL---QDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLE 722
Query: 723 TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYE----- 777
+ + Q+++ + ++ ++ + + ALQ + + + + + +L + + E
Sbjct: 723 QKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVS 782
Query: 778 SMQANIRNMEDA-----QRIAELETEVSEYKLKNEVMATEGELRNNNMDD--SDRVRELQ 830
S + +++ +A Q++ + E E K E ++ E ++++ +++ V ELQ
Sbjct: 783 STRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQ 842
Query: 831 EQVAELKAEIMRLEAWKSR 849
+ E +A + L K +
Sbjct: 843 KVKMEKEALMTELSTVKDK 861
Score = 32.7 bits (71), Expect = 5.9
Identities = 48/252 (19%), Positives = 104/252 (41%), Gaps = 18/252 (7%)
Query: 610 DNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
++N+A +D++ ++ + SLK+ + EL + +++ +QEA +V
Sbjct: 75 ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAK----PDGLV 130
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVST 729
+D A + L + E + + + + + TE+ +++ K E + + +
Sbjct: 131 TDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAE 190
Query: 730 NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDA 789
++ R EE N +A + ++ + QR A L K + +Q + NM
Sbjct: 191 QKVTRLTEEL-----NKEATVIQDLKTELLQRPGIEDVAVL--KKELVQVQTLMDNM--- 240
Query: 790 QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSR 849
LE E KLK+E + + ++ S EL + E+ + L+ KS
Sbjct: 241 ----TLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSS 296
Query: 850 ALGHTELSRAIS 861
T+ ++ ++
Sbjct: 297 VNELTQKNQTLT 308
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 52.0 bits (119), Expect = 9e-06
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 457 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 513
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 514 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 573
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 574 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 633
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 634 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 686
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 687 STAQKN--ESSR-QQLERQNKELRSKLHEMEGAVKSK 720
Score = 44.0 bits (99), Expect = 0.002
Identities = 75/369 (20%), Positives = 156/369 (42%), Gaps = 34/369 (9%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESAS 558
+EET + + +VQ +R+ + + L L++ + + + +N + L G
Sbjct: 93 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 152
Query: 559 GQKHEELA---RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RR 606
GQ +E+ + L+ + +L+NE +S+ +
Sbjct: 153 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA 212
Query: 607 QRVDNNVA----HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAP 660
++ +VA LQD EL+ + R+ + N+S K LRQ + E S Q L E +
Sbjct: 213 IKLAKDVASLSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQ 269
Query: 661 AAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL---- 716
+ ++ ++ KK L+ + A ++ EE +E+E LT+ E +
Sbjct: 270 NLERHISTLNIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 325
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
K+ + + ++Q + L + R L NL+ ++ L ++ KYAD +A+
Sbjct: 326 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 385
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAE 835
E+ + + + A+ + E E + N+++ E E ++ DD V EL++
Sbjct: 386 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 445
Query: 836 LKAEIMRLE 844
L+ ++ ++
Sbjct: 446 LETQMEEMK 454
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 52.0 bits (119), Expect = 9e-06
Identities = 68/362 (18%), Positives = 158/362 (43%), Gaps = 28/362 (7%)
Query: 493 VRGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRS--LEMTIAENNSRQSS 550
++ Q + E+E L + L++++ ++++ E++ L+ T EN +Q
Sbjct: 941 IQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQL 1000
Query: 551 LEGTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVD 610
+ + + +K E LQ + + KS V+
Sbjct: 1001 TQAAQELAAEK--EKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKS-----VE 1053
Query: 611 NNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL---SESWQRHLQEHKQEAPAAPVQSN 667
++ Q++LI+ + + N +++L+ + L S ++ LQE + + +
Sbjct: 1054 EKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKS 1113
Query: 668 VVSDIMATPKKLLRAWEG----RSADMLKLDEELMTTRIREVEALTELKELRLKVMELET 723
+ + K L E + ++ KL+EEL + ++ ++ +T LK+ + +++ +
Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKL 1173
Query: 724 QVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANI 783
++Q + L+ E+ + ++ L +++E + ++EF K A L S+ K + +
Sbjct: 1174 ELQGKADSLKAAVEQEKRNQQILKDQVKKEE--EELKKEFIEKEAKLHSEIK--EKEVGM 1229
Query: 784 RNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
+ E+ + A+L +++ NE + G ++ RV EL++Q +L+ EI L
Sbjct: 1230 KKHEENE--AKLTMQITAL---NENL---GTVKKEWQSSQRRVSELEKQTDDLRGEIAVL 1281
Query: 844 EA 845
EA
Sbjct: 1282 EA 1283
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/262 (19%), Positives = 120/262 (45%), Gaps = 17/262 (6%)
Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEA 659
+N +L R+R L+DE + + A + ++ LR +S+ + + ++QE ++
Sbjct: 238 DNMTLERERESEK---LKDESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQK-- 292
Query: 660 PAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVM 719
++S+V +++ + L + D KL+E+ + + L + L
Sbjct: 293 ----LKSSV-NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQ 347
Query: 720 ELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESM 779
+L++++ S L R E L E +A + + L + ++QH A+ + + + +
Sbjct: 348 QLQSRLSASETSLHRIHVE---LSEKGEATQKLKEELSEVETKYQHLKAEFK-QLQQQRE 403
Query: 780 QANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
+ ++ I +L +++ E + ++ G L+ S+++ + ++QVA+L+ +
Sbjct: 404 EKEQHGLQLQSEINQLHSKLLE--TERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLK 461
Query: 840 IMRL-EAWKSRALGHTELSRAI 860
+ RL E K + TEL +
Sbjct: 462 LSRLEEQLKEKVTNSTELQHQL 483
Score = 44.0 bits (99), Expect = 0.002
Identities = 88/442 (19%), Positives = 177/442 (40%), Gaps = 57/442 (12%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQ---GDIA 462
D+E +L+ I E DQ NL ++ + + + LEKE + K Q G+ A
Sbjct: 510 DLEQVLRQI-------GEKDQK-IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETA 561
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRRANVD 522
VL L+++N L+ V V+ Q + + +E L +VQ +
Sbjct: 562 VLNQLQEKNHTLQDEVTQLTEN--------VKNQSESHKQAQEN--LHDQVQ-------E 604
Query: 523 MQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXX 582
+ L A D + SLE ++ E NS+ + S +K +L ++
Sbjct: 605 QKAHLRAAQDRVLSLETSVNELNSQLNE-------SKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 583 XXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVS 642
+D +N +L+ + + N Q + + KL++ + + S Q S
Sbjct: 658 KTAQRADLQNHLDTAQN---ALQDKHQELNKITTQLDQVTAKLQDKQEHCS-----QLES 709
Query: 643 ELSESWQRHLQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTR 701
L E +++L E K E ++ + K + + L D EL T
Sbjct: 710 HLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATE 769
Query: 702 I-REVEALTEL-KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ +++E E+ RL + + ++ +L +Q+EE ++L+++ + Q
Sbjct: 770 LSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQ-------- 821
Query: 760 QREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY-KLKNEVMATEGELRNN 818
+ + QH+ +L ++ + + ME + EL T + K+ + + ++ E
Sbjct: 822 ETKIQHE--ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKE 879
Query: 819 NMDDSDRVRELQEQVAELKAEI 840
N + +L++ ELK ++
Sbjct: 880 NQKGKAAILDLEKTCKELKHQL 901
Score = 37.9 bits (84), Expect = 0.16
Identities = 33/158 (20%), Positives = 75/158 (47%), Gaps = 5/158 (3%)
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQ 751
KL+ + + + + +AL +L++ R +LE + + QL + E R +L +
Sbjct: 734 KLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSE 793
Query: 752 RERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMAT 811
+++ + + + + L+ + S + I++ E RI TE+ + K++ E + T
Sbjct: 794 ALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMT 853
Query: 812 E-GELRNNNMDDSDRVR----ELQEQVAELKAEIMRLE 844
E +++ SD ++ E +++ + KA I+ LE
Sbjct: 854 ELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLE 891
Score = 35.9 bits (79), Expect = 0.64
Identities = 81/439 (18%), Positives = 186/439 (42%), Gaps = 45/439 (10%)
Query: 441 KKMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRA 500
K+ ++L E + K ++ D+ L+ R E +L K++V ++ Q+D+
Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQ-LKLSRLEEQL-KEKVTNSTE---------LQHQLDKT 486
Query: 501 EGE-EETFALDREVQA-LRRANVDMQQ---RLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
+ + +E AL + A LR A D++Q ++ +I++LE + ++ S LE
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKER 546
Query: 556 S---ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
A Q E L + + ++L Q V
Sbjct: 547 EDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQ-VQEQ 605
Query: 613 VAHL---QDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
AHL QD +++++ E N L + +++VS+L + + A Q +
Sbjct: 606 KAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADL 665
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEEL--MTTRIREVEAL-----TELKELRLKVMELE 722
+ + T + L + + ++ K+ +L +T ++++ + + LKE + K + LE
Sbjct: 666 QNHLDTAQNAL---QDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLE 722
Query: 723 TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYE----- 777
+ + Q+++ + ++ ++ + + ALQ + + + + + +L + + E
Sbjct: 723 QKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVS 782
Query: 778 SMQANIRNMEDA-----QRIAELETEVSEYKLKNEVMATEGELRNNNMDD--SDRVRELQ 830
S + +++ +A Q++ + E E K E ++ E ++++ +++ V ELQ
Sbjct: 783 STRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQ 842
Query: 831 EQVAELKAEIMRLEAWKSR 849
+ E +A + L K +
Sbjct: 843 KVKMEKEALMTELSTVKDK 861
Score = 34.7 bits (76), Expect = 1.5
Identities = 49/252 (19%), Positives = 105/252 (41%), Gaps = 18/252 (7%)
Query: 610 DNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
++N+A +D++ ++ + SLK+ + EL + +++ +QEA +V
Sbjct: 75 ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAK----PDGLV 130
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVST 729
+D A + L + E + + + + + TE+ +++ K E + + +
Sbjct: 131 TDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAE 190
Query: 730 NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDA 789
++ R EE N +A + ++ + QR A L K + +Q + NM
Sbjct: 191 QKVTRLTEEL-----NKEATVIQDLKTELLQRPGIEDVAVL--KKELVQVQTLMDNM--- 240
Query: 790 QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSR 849
LE E KLK+E E + ++ S EL + E++ + L+ KS
Sbjct: 241 ----TLERERESEKLKDESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQKLKSS 296
Query: 850 ALGHTELSRAIS 861
T+ ++ ++
Sbjct: 297 VNELTQKNQTLT 308
>BX640704-1|CAE45824.1| 594|Homo sapiens hypothetical protein
protein.
Length = 594
Score = 52.0 bits (119), Expect = 9e-06
Identities = 72/315 (22%), Positives = 136/315 (43%), Gaps = 13/315 (4%)
Query: 523 MQQRLAV-ALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
+Q ++++ + D +E +AENN+ ++SL E K +EL L+
Sbjct: 203 LQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQEL-NMLREQTTGLAAELQ 261
Query: 582 XXXXXXXXXXXXIDELENE-NKSLR-RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQ 639
D+L ++ +SLR R+ + + E + EA S + +
Sbjct: 262 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKA 321
Query: 640 RVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
+ EL+ + +HK+E A ++ +++ + R D + +EEL
Sbjct: 322 MLDELAMETLQEKSQHKEELGAVRLRHE--KEVLGVRARYERELRELHEDKKRQEEEL-R 378
Query: 700 TRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+IRE +A T EL+ L+ V EL+ QV S + + E R L+E ++ Q+++ +
Sbjct: 379 GQIREEKARTRELETLQQTVEELQAQVH-SMDGAKGWFE--RRLKEAEESLQQQQQEQEE 435
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ + ++A E K K E +Q +E AQ + + LK EV T R
Sbjct: 436 ALKQCREQHA-AELKGKEEELQDVRDQLEQAQEERDCHLKTIS-SLKQEVKDTVDGQRIL 493
Query: 819 NMDDSDRVRELQEQV 833
S +++L+ Q+
Sbjct: 494 EKKGSAALKDLKRQL 508
>BX530088-3|CAI95786.1| 841|Homo sapiens GRIP1 associated protein 1
protein.
Length = 841
Score = 52.0 bits (119), Expect = 9e-06
Identities = 72/315 (22%), Positives = 136/315 (43%), Gaps = 13/315 (4%)
Query: 523 MQQRLAV-ALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
+Q ++++ + D +E +AENN+ ++SL E K +EL L+
Sbjct: 313 LQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQEL-NMLREQTTGLAAELQ 371
Query: 582 XXXXXXXXXXXXIDELENE-NKSLR-RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQ 639
D+L ++ +SLR R+ + + E + EA S + +
Sbjct: 372 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKA 431
Query: 640 RVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
+ EL+ + +HK+E A ++ +++ + R D + +EEL
Sbjct: 432 MLDELAMETLQEKSQHKEELGAVRLRHE--KEVLGVRARYERELRELHEDKKRQEEEL-R 488
Query: 700 TRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+IRE +A T EL+ L+ V EL+ QV S + + E R L+E ++ Q+++ +
Sbjct: 489 GQIREEKARTRELETLQQTVEELQAQVH-SMDGAKGWFE--RRLKEAEESLQQQQQEQEE 545
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ + ++A E K K E +Q +E AQ + + LK EV T R
Sbjct: 546 ALKQCREQHA-AELKGKEEELQDVRDQLEQAQEERDCHLKTIS-SLKQEVKDTVDGQRIL 603
Query: 819 NMDDSDRVRELQEQV 833
S +++L+ Q+
Sbjct: 604 EKKGSAALKDLKRQL 618
>BX530088-2|CAI95785.1| 796|Homo sapiens GRIP1 associated protein 1
protein.
Length = 796
Score = 52.0 bits (119), Expect = 9e-06
Identities = 72/315 (22%), Positives = 136/315 (43%), Gaps = 13/315 (4%)
Query: 523 MQQRLAV-ALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
+Q ++++ + D +E +AENN+ ++SL E K +EL L+
Sbjct: 268 LQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQEL-NMLREQTTGLAAELQ 326
Query: 582 XXXXXXXXXXXXIDELENE-NKSLR-RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQ 639
D+L ++ +SLR R+ + + E + EA S + +
Sbjct: 327 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKA 386
Query: 640 RVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
+ EL+ + +HK+E A ++ +++ + R D + +EEL
Sbjct: 387 MLDELAMETLQEKSQHKEELGAVRLRHE--KEVLGVRARYERELRELHEDKKRQEEEL-R 443
Query: 700 TRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+IRE +A T EL+ L+ V EL+ QV S + + E R L+E ++ Q+++ +
Sbjct: 444 GQIREEKARTRELETLQQTVEELQAQVH-SMDGAKGWFE--RRLKEAEESLQQQQQEQEE 500
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ + ++A E K K E +Q +E AQ + + LK EV T R
Sbjct: 501 ALKQCREQHA-AELKGKEEELQDVRDQLEQAQEERDCHLKTIS-SLKQEVKDTVDGQRIL 558
Query: 819 NMDDSDRVRELQEQV 833
S +++L+ Q+
Sbjct: 559 EKKGSAALKDLKRQL 573
>BC101546-1|AAI01547.1| 841|Homo sapiens GRIP1 associated protein 1
protein.
Length = 841
Score = 52.0 bits (119), Expect = 9e-06
Identities = 72/315 (22%), Positives = 136/315 (43%), Gaps = 13/315 (4%)
Query: 523 MQQRLAV-ALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
+Q ++++ + D +E +AENN+ ++SL E K +EL L+
Sbjct: 313 LQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQEL-NMLREQTTGLAAELQ 371
Query: 582 XXXXXXXXXXXXIDELENE-NKSLR-RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQ 639
D+L ++ +SLR R+ + + E + EA S + +
Sbjct: 372 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKA 431
Query: 640 RVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
+ EL+ + +HK+E A ++ +++ + R D + +EEL
Sbjct: 432 MLDELAMETLQEKSQHKEELGAVRLRHE--KEVLGVRARYERELRELHEDKKRQEEEL-R 488
Query: 700 TRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+IRE +A T EL+ L+ V EL+ QV S + + E R L+E ++ Q+++ +
Sbjct: 489 GQIREEKARTRELETLQQTVEELQAQVH-SMDGAKGWFE--RRLKEAEESLQQQQQEQEE 545
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ + ++A E K K E +Q +E AQ + + LK EV T R
Sbjct: 546 ALKQCREQHA-AELKGKEEELQDVRDQLEQAQEERDCHLKTIS-SLKQEVKDTVDGQRIL 603
Query: 819 NMDDSDRVRELQEQV 833
S +++L+ Q+
Sbjct: 604 EKKGSAALKDLKRQL 618
>BC101544-1|AAI01545.1| 841|Homo sapiens GRIP1 associated protein 1
protein.
Length = 841
Score = 52.0 bits (119), Expect = 9e-06
Identities = 72/315 (22%), Positives = 136/315 (43%), Gaps = 13/315 (4%)
Query: 523 MQQRLAV-ALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
+Q ++++ + D +E +AENN+ ++SL E K +EL L+
Sbjct: 313 LQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQEL-NMLREQTTGLAAELQ 371
Query: 582 XXXXXXXXXXXXIDELENE-NKSLR-RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQ 639
D+L ++ +SLR R+ + + E + EA S + +
Sbjct: 372 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKA 431
Query: 640 RVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
+ EL+ + +HK+E A ++ +++ + R D + +EEL
Sbjct: 432 MLDELAMETLQEKSQHKEELGAVRLRHE--KEVLGVRARYERELRELHEDKKRQEEEL-R 488
Query: 700 TRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+IRE +A T EL+ L+ V EL+ QV S + + E R L+E ++ Q+++ +
Sbjct: 489 GQIREEKARTRELETLQQTVEELQAQVH-SMDGAKGWFE--RRLKEAEESLQQQQQEQEE 545
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ + ++A E K K E +Q +E AQ + + LK EV T R
Sbjct: 546 ALKQCREQHA-AELKGKEEELQDVRDQLEQAQEERDCHLKTIS-SLKQEVKDTVDGQRIL 603
Query: 819 NMDDSDRVRELQEQV 833
S +++L+ Q+
Sbjct: 604 EKKGSAALKDLKRQL 618
>BC001522-1|AAH01522.2| 557|Homo sapiens GRIPAP1 protein protein.
Length = 557
Score = 52.0 bits (119), Expect = 9e-06
Identities = 72/315 (22%), Positives = 136/315 (43%), Gaps = 13/315 (4%)
Query: 523 MQQRLAV-ALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
+Q ++++ + D +E +AENN+ ++SL E K +EL L+
Sbjct: 29 LQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQEL-NMLREQTTGLAAELQ 87
Query: 582 XXXXXXXXXXXXIDELENE-NKSLR-RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQ 639
D+L ++ +SLR R+ + + E + EA S + +
Sbjct: 88 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKA 147
Query: 640 RVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
+ EL+ + +HK+E A ++ +++ + R D + +EEL
Sbjct: 148 MLDELAMETLQEKSQHKEELGAVRLRHE--KEVLGVRARYERELRELHEDKKRQEEEL-R 204
Query: 700 TRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+IRE +A T EL+ L+ V EL+ QV S + + E R L+E ++ Q+++ +
Sbjct: 205 GQIREEKARTRELETLQQTVEELQAQVH-SMDGAKGWFE--RRLKEAEESLQQQQQEQEE 261
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ + ++A E K K E +Q +E AQ + + LK EV T R
Sbjct: 262 ALKQCREQHA-AELKGKEEELQDVRDQLEQAQEERDCHLKTIS-SLKQEVKDTVDGQRIL 319
Query: 819 NMDDSDRVRELQEQV 833
S +++L+ Q+
Sbjct: 320 EKKGSAALKDLKRQL 334
>AB032993-1|BAA86481.1| 834|Homo sapiens KIAA1167 protein protein.
Length = 834
Score = 52.0 bits (119), Expect = 9e-06
Identities = 72/315 (22%), Positives = 136/315 (43%), Gaps = 13/315 (4%)
Query: 523 MQQRLAV-ALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXX 581
+Q ++++ + D +E +AENN+ ++SL E K +EL L+
Sbjct: 306 LQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQEL-NMLREQTTGLAAELQ 364
Query: 582 XXXXXXXXXXXXIDELENE-NKSLR-RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQ 639
D+L ++ +SLR R+ + + E + EA S + +
Sbjct: 365 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKA 424
Query: 640 RVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMT 699
+ EL+ + +HK+E A ++ +++ + R D + +EEL
Sbjct: 425 MLDELAMETLQEKSQHKEELGAVRLRHE--KEVLGVRARYERELRELHEDKKRQEEEL-R 481
Query: 700 TRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+IRE +A T EL+ L+ V EL+ QV S + + E R L+E ++ Q+++ +
Sbjct: 482 GQIREEKARTRELETLQQTVEELQAQVH-SMDGAKGWFE--RRLKEAEESLQQQQQEQEE 538
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ + ++A E K K E +Q +E AQ + + LK EV T R
Sbjct: 539 ALKQCREQHA-AELKGKEEELQDVRDQLEQAQEERDCHLKTIS-SLKQEVKDTVDGQRIL 596
Query: 819 NMDDSDRVRELQEQV 833
S +++L+ Q+
Sbjct: 597 EKKGSAALKDLKRQL 611
>BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein
protein.
Length = 724
Score = 51.6 bits (118), Expect = 1e-05
Identities = 76/364 (20%), Positives = 155/364 (42%), Gaps = 28/364 (7%)
Query: 499 RAEGEEETFALDREVQALRR--ANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTES 556
+ E ++E D ++AL+ + ++ R + EIR E+ + N + + E E
Sbjct: 374 KGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEIRKEELVL-HLNQLEGNKEKFEK 432
Query: 557 ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHL 616
+K EE+ CLQ L+ + + L+++ + N L
Sbjct: 433 QLKKKSEEVY-CLQKELKIKNHSLQETSEQNVILQHT---LQQQQQMLQQETIRNG--EL 486
Query: 617 QDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATP 676
+D KL + + L + +QR S +E ++ ++ + A A ++ V ++ T
Sbjct: 487 EDT--QTKLEKQVSKLEQELQKQRESS-AEKLRKMEEKCESAAHEADLKRQKVIELTGTA 543
Query: 677 KKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQD 736
+++ + ++ K+++E+M + L +L + + + +T+++ TN ++ +
Sbjct: 544 RQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELE 603
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+ L ALQ+ L+T E Q+ + +L+S + ++ + D + A+L
Sbjct: 604 KLQHSTETELTEALQKREVLET---ELQNAHGELKSTLR------QLQELRDVLQKAQLS 654
Query: 797 TEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTEL 856
E +Y ++ A ELR M+ D+ +EL E LK L K RA T L
Sbjct: 655 LE-EKYTTIKDLTA---ELRECKMEIEDKKQELLEMDQALKERNWEL---KQRAAQVTHL 707
Query: 857 SRAI 860
I
Sbjct: 708 DMTI 711
Score = 35.5 bits (78), Expect = 0.84
Identities = 41/236 (17%), Positives = 97/236 (41%), Gaps = 16/236 (6%)
Query: 624 KLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAW 683
++++ ANL+ L Q + ++S + + P V + + +
Sbjct: 174 EIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQ 233
Query: 684 EGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLR 743
+ L E + T++ ++EA E +L++ + +Q Q+ +L + + L
Sbjct: 234 YEKERQGLVTGIEELRTKLIQIEA--ENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLE 291
Query: 744 ENLDAALQRERALQTRQRE-------FQHKYADLESK----AKYESMQANIRNMEDAQRI 792
+ + L+ + E K A+LE + A+ E + E +
Sbjct: 292 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMLEAQLEKKDQQFKEQEKTMSM 351
Query: 793 AELETEVSEYKLKN-EVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
+ + ++ L++ + + TE GE++ NM + ++ LQ QV+E ++ +L++
Sbjct: 352 LQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDS 407
>BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil
domain containing 1 protein.
Length = 1478
Score = 51.6 bits (118), Expect = 1e-05
Identities = 88/370 (23%), Positives = 145/370 (39%), Gaps = 38/370 (10%)
Query: 504 EETFALDREVQALRRANVDMQQRLAVALDEIR-------SLEMTIAENNSRQSSLEGTES 556
E+ AL+RE + N +L + E++ SLE + E Q L G
Sbjct: 405 EKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSG--- 461
Query: 557 ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDE---LENENKSLRRQRVDNNV 613
GQ+ ++L R LQ +E LE E +SL RQ +
Sbjct: 462 -KGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQ-----L 515
Query: 614 AHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
L+ +L V ++ K L Q LS+ + P PV ++
Sbjct: 516 QFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALV 575
Query: 674 ATPKKLLRAWEGRSADMLKLDE-ELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
L AW + L E +L T+++E EL++ + +E E Q V NQL
Sbjct: 576 PVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQAN-RELEKELQNVVGRNQL 634
Query: 733 RRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
+A L+ + A QRE A+Q S A E+ QA+IR++ D
Sbjct: 635 LEGKLQA--LQADYQALQQRESAIQ-------------GSLASLEAEQASIRHLGDQMEA 679
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAEL-KAEIMRLEAWKSRAL 851
+ L ++ +K ++ E L++ + ++RE EQ +L +A L A +S+
Sbjct: 680 SLLAVRKAKEAMKAQMAEKEAILQSKE-GECQQLREEVEQCQQLAEARHRELRALESQCQ 738
Query: 852 GHTELSRAIS 861
T+L ++
Sbjct: 739 QQTQLIEVLT 748
Score = 39.5 bits (88), Expect = 0.052
Identities = 81/364 (22%), Positives = 148/364 (40%), Gaps = 42/364 (11%)
Query: 512 EVQALRRANVDMQQRLAVALD-------EIRSLEMTIAENNSRQSSLEGTESASGQKH-E 563
EVQ L+ VD+Q ++ ALD ++ E + E+ + L+ A + H +
Sbjct: 784 EVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQ 843
Query: 564 ELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAV 623
EL +C + +EL S ++++ A LQ++L
Sbjct: 844 ELLQCSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEH--AELQEQLHRA 901
Query: 624 KLREAEANLSLKDL---RQRVSELSESWQRHLQEHKQEAP-AAPVQSNVVSDIMATPKKL 679
AE + + L ++RV E + LQ+ K+ A V+ + + L
Sbjct: 902 NTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESL 961
Query: 680 ---LRAWEGRSADMLKLDEELMTTRIREVEALTEL--KELRLKVMELETQVQVSTNQLRR 734
L+A + + + L +L R ++L E +EL +L ++ ++L+
Sbjct: 962 QEKLKAAKAAAGSLPGLQAQLAQAEQR-AQSLQEAAHQELNTLKFQLSAEIMDYQSRLKN 1020
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK------YESMQANIRN--- 785
EE + LR L+ ++ +A + + + AD+ K E A +R
Sbjct: 1021 AGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKE 1080
Query: 786 ----MEDAQRI-AELE---TEVSEY--KLKNEVMATE--GELRNNNMDDSDRVRE-LQEQ 832
ED +R ELE T++ EY KL EV E + ++DD +R ++ L+E+
Sbjct: 1081 GAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEER 1140
Query: 833 VAEL 836
+ EL
Sbjct: 1141 LIEL 1144
Score = 38.3 bits (85), Expect = 0.12
Identities = 95/429 (22%), Positives = 161/429 (37%), Gaps = 37/429 (8%)
Query: 442 KMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
K++ L+ +Y ++ +E L L E ++ + AE
Sbjct: 638 KLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAE 697
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQK 561
E + + E Q LR V+ Q+LA E R E+ E+ +Q + + E + +K
Sbjct: 698 KEAILQSKEGECQQLRE-EVEQCQQLA----EARHRELRALESQCQQQT-QLIEVLTAEK 751
Query: 562 HEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV---AHLQD 618
+ Q ++ + E + L+ Q VD A L D
Sbjct: 752 GQ------QGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDD 805
Query: 619 E-LIAVKLREAEANL-SLKDLRQRVSELSESWQR-HLQEHKQEAPAAPVQSNVVSDIMAT 675
+ + +L AEA L K L Q++ E +E+ R H+QE Q + +D
Sbjct: 806 QDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQ 865
Query: 676 PKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQ 735
++ LRA + + EE ++ E +L EL QV T + R
Sbjct: 866 REEELRALQEELSQAKCSSEE---AQLEHAELQEQLHRANTDTAELGIQVCALTVEKERV 922
Query: 736 DEE-ARLLRENLDA--ALQRER--------ALQTRQREFQHKYADLESKA-KYESMQANI 783
+E A ++E DA A RER LQ + Q K ++ A +QA +
Sbjct: 923 EEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQL 982
Query: 784 RNMEDA----QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E Q A E +++L E+M + L+N + +L+EQ +L+A
Sbjct: 983 AQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAA 1042
Query: 840 IMRLEAWKS 848
+E K+
Sbjct: 1043 EEAVEKLKA 1051
Score = 34.7 bits (76), Expect = 1.5
Identities = 66/300 (22%), Positives = 110/300 (36%), Gaps = 25/300 (8%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG-- 553
+V + E LDRE Q LR A ++L + R T AE+N R + L
Sbjct: 243 EVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGR----TAAEDNVRLTCLVAEL 298
Query: 554 -----TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQR 608
A+ +EL CLQ + L E ++ R
Sbjct: 299 QKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATR-DS 357
Query: 609 VDNNVAHLQD--ELIAVKLREAEANLSLK--------DLRQRVSELSESWQRHLQEHKQE 658
+D HL +A+ ++A+ K D Q + EL E Q +E +
Sbjct: 358 LDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKV 417
Query: 659 APAAPVQSNVVSDIMATP--KKLLRA-WEGRSADMLKLDEELMTTRIREVEALTELKELR 715
QS + ++ K+ RA E +M L EEL + L+EL
Sbjct: 418 EEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELL 477
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
E ++ + ++Q EE LL + + + ++ + L+T+ + +DLE + K
Sbjct: 478 AHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKK 537
>BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil
domain containing 1 protein.
Length = 1478
Score = 51.6 bits (118), Expect = 1e-05
Identities = 88/370 (23%), Positives = 145/370 (39%), Gaps = 38/370 (10%)
Query: 504 EETFALDREVQALRRANVDMQQRLAVALDEIR-------SLEMTIAENNSRQSSLEGTES 556
E+ AL+RE + N +L + E++ SLE + E Q L G
Sbjct: 405 EKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSG--- 461
Query: 557 ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDE---LENENKSLRRQRVDNNV 613
GQ+ ++L R LQ +E LE E +SL RQ +
Sbjct: 462 -KGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQ-----L 515
Query: 614 AHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
L+ +L V ++ K L Q LS+ + P PV ++
Sbjct: 516 QFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALV 575
Query: 674 ATPKKLLRAWEGRSADMLKLDE-ELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
L AW + L E +L T+++E EL++ + +E E Q V NQL
Sbjct: 576 PVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQAN-RELEKELQNVVGRNQL 634
Query: 733 RRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
+A L+ + A QRE A+Q S A E+ QA+IR++ D
Sbjct: 635 LEGKLQA--LQADYQALQQRESAIQ-------------GSLASLEAEQASIRHLGDQMEA 679
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAEL-KAEIMRLEAWKSRAL 851
+ L ++ +K ++ E L++ + ++RE EQ +L +A L A +S+
Sbjct: 680 SLLAVRKAKEAMKAQMAEKEAILQSKE-GECQQLREEVEQCQQLAEARHRELRALESQCQ 738
Query: 852 GHTELSRAIS 861
T+L ++
Sbjct: 739 QQTQLIEVLT 748
Score = 39.5 bits (88), Expect = 0.052
Identities = 81/364 (22%), Positives = 148/364 (40%), Gaps = 42/364 (11%)
Query: 512 EVQALRRANVDMQQRLAVALD-------EIRSLEMTIAENNSRQSSLEGTESASGQKH-E 563
EVQ L+ VD+Q ++ ALD ++ E + E+ + L+ A + H +
Sbjct: 784 EVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQ 843
Query: 564 ELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAV 623
EL +C + +EL S ++++ A LQ++L
Sbjct: 844 ELLQCSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEH--AELQEQLHRA 901
Query: 624 KLREAEANLSLKDL---RQRVSELSESWQRHLQEHKQEAP-AAPVQSNVVSDIMATPKKL 679
AE + + L ++RV E + LQ+ K+ A V+ + + L
Sbjct: 902 NTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESL 961
Query: 680 ---LRAWEGRSADMLKLDEELMTTRIREVEALTEL--KELRLKVMELETQVQVSTNQLRR 734
L+A + + + L +L R ++L E +EL +L ++ ++L+
Sbjct: 962 QEKLKAAKAAAGSLPGLQAQLAQAEQR-AQSLQEAAHQELNTLKFQLSAEIMDYQSRLKN 1020
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK------YESMQANIRN--- 785
EE + LR L+ ++ +A + + + AD+ K E A +R
Sbjct: 1021 AGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKE 1080
Query: 786 ----MEDAQRI-AELE---TEVSEY--KLKNEVMATE--GELRNNNMDDSDRVRE-LQEQ 832
ED +R ELE T++ EY KL EV E + ++DD +R ++ L+E+
Sbjct: 1081 GAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEER 1140
Query: 833 VAEL 836
+ EL
Sbjct: 1141 LIEL 1144
Score = 38.3 bits (85), Expect = 0.12
Identities = 95/429 (22%), Positives = 161/429 (37%), Gaps = 37/429 (8%)
Query: 442 KMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
K++ L+ +Y ++ +E L L E ++ + AE
Sbjct: 638 KLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAE 697
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQK 561
E + + E Q LR V+ Q+LA E R E+ E+ +Q + + E + +K
Sbjct: 698 KEAILQSKEGECQQLRE-EVEQCQQLA----EARHRELRALESQCQQQT-QLIEVLTAEK 751
Query: 562 HEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV---AHLQD 618
+ Q ++ + E + L+ Q VD A L D
Sbjct: 752 GQ------QGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDD 805
Query: 619 E-LIAVKLREAEANL-SLKDLRQRVSELSESWQR-HLQEHKQEAPAAPVQSNVVSDIMAT 675
+ + +L AEA L K L Q++ E +E+ R H+QE Q + +D
Sbjct: 806 QDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQ 865
Query: 676 PKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQ 735
++ LRA + + EE ++ E +L EL QV T + R
Sbjct: 866 REEELRALQEELSQAKCSSEE---AQLEHAELQEQLHRANTDTAELGIQVCALTVEKERV 922
Query: 736 DEE-ARLLRENLDA--ALQRER--------ALQTRQREFQHKYADLESKA-KYESMQANI 783
+E A ++E DA A RER LQ + Q K ++ A +QA +
Sbjct: 923 EEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQL 982
Query: 784 RNMEDA----QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E Q A E +++L E+M + L+N + +L+EQ +L+A
Sbjct: 983 AQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAA 1042
Query: 840 IMRLEAWKS 848
+E K+
Sbjct: 1043 EEAVEKLKA 1051
Score = 34.7 bits (76), Expect = 1.5
Identities = 66/300 (22%), Positives = 110/300 (36%), Gaps = 25/300 (8%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG-- 553
+V + E LDRE Q LR A ++L + R T AE+N R + L
Sbjct: 243 EVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGR----TAAEDNVRLTCLVAEL 298
Query: 554 -----TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQR 608
A+ +EL CLQ + L E ++ R
Sbjct: 299 QKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATR-DS 357
Query: 609 VDNNVAHLQD--ELIAVKLREAEANLSLK--------DLRQRVSELSESWQRHLQEHKQE 658
+D HL +A+ ++A+ K D Q + EL E Q +E +
Sbjct: 358 LDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKV 417
Query: 659 APAAPVQSNVVSDIMATP--KKLLRA-WEGRSADMLKLDEELMTTRIREVEALTELKELR 715
QS + ++ K+ RA E +M L EEL + L+EL
Sbjct: 418 EEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELL 477
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
E ++ + ++Q EE LL + + + ++ + L+T+ + +DLE + K
Sbjct: 478 AHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKK 537
>AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil
domain containing 1 protein.
Length = 1478
Score = 51.6 bits (118), Expect = 1e-05
Identities = 88/370 (23%), Positives = 145/370 (39%), Gaps = 38/370 (10%)
Query: 504 EETFALDREVQALRRANVDMQQRLAVALDEIR-------SLEMTIAENNSRQSSLEGTES 556
E+ AL+RE + N +L + E++ SLE + E Q L G
Sbjct: 405 EKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSG--- 461
Query: 557 ASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDE---LENENKSLRRQRVDNNV 613
GQ+ ++L R LQ +E LE E +SL RQ +
Sbjct: 462 -KGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQ-----L 515
Query: 614 AHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
L+ +L V ++ K L Q LS+ + P PV ++
Sbjct: 516 QFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALV 575
Query: 674 ATPKKLLRAWEGRSADMLKLDE-ELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
L AW + L E +L T+++E EL++ + +E E Q V NQL
Sbjct: 576 PVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQAN-RELEKELQNVVGRNQL 634
Query: 733 RRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
+A L+ + A QRE A+Q S A E+ QA+IR++ D
Sbjct: 635 LEGKLQA--LQADYQALQQRESAIQ-------------GSLASLEAEQASIRHLGDQMEA 679
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAEL-KAEIMRLEAWKSRAL 851
+ L ++ +K ++ E L++ + ++RE EQ +L +A L A +S+
Sbjct: 680 SLLAVRKAKEAMKAQMAEKEAILQSKE-GECQQLREEVEQCQQLAEARHRELRALESQCQ 738
Query: 852 GHTELSRAIS 861
T+L ++
Sbjct: 739 QQTQLIEVLT 748
Score = 39.5 bits (88), Expect = 0.052
Identities = 81/364 (22%), Positives = 148/364 (40%), Gaps = 42/364 (11%)
Query: 512 EVQALRRANVDMQQRLAVALD-------EIRSLEMTIAENNSRQSSLEGTESASGQKH-E 563
EVQ L+ VD+Q ++ ALD ++ E + E+ + L+ A + H +
Sbjct: 784 EVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQ 843
Query: 564 ELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAV 623
EL +C + +EL S ++++ A LQ++L
Sbjct: 844 ELLQCSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEH--AELQEQLHRA 901
Query: 624 KLREAEANLSLKDL---RQRVSELSESWQRHLQEHKQEAP-AAPVQSNVVSDIMATPKKL 679
AE + + L ++RV E + LQ+ K+ A V+ + + L
Sbjct: 902 NTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESL 961
Query: 680 ---LRAWEGRSADMLKLDEELMTTRIREVEALTEL--KELRLKVMELETQVQVSTNQLRR 734
L+A + + + L +L R ++L E +EL +L ++ ++L+
Sbjct: 962 QEKLKAAKAAAGSLPGLQAQLAQAEQR-AQSLQEAAHQELNTLKFQLSAEIMDYQSRLKN 1020
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK------YESMQANIRN--- 785
EE + LR L+ ++ +A + + + AD+ K E A +R
Sbjct: 1021 AGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKE 1080
Query: 786 ----MEDAQRI-AELE---TEVSEY--KLKNEVMATE--GELRNNNMDDSDRVRE-LQEQ 832
ED +R ELE T++ EY KL EV E + ++DD +R ++ L+E+
Sbjct: 1081 GAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEER 1140
Query: 833 VAEL 836
+ EL
Sbjct: 1141 LIEL 1144
Score = 38.3 bits (85), Expect = 0.12
Identities = 95/429 (22%), Positives = 161/429 (37%), Gaps = 37/429 (8%)
Query: 442 KMKKLEKEYTVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAE 501
K++ L+ +Y ++ +E L L E ++ + AE
Sbjct: 638 KLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAE 697
Query: 502 GEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQK 561
E + + E Q LR V+ Q+LA E R E+ E+ +Q + + E + +K
Sbjct: 698 KEAILQSKEGECQQLRE-EVEQCQQLA----EARHRELRALESQCQQQT-QLIEVLTAEK 751
Query: 562 HEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV---AHLQD 618
+ Q ++ + E + L+ Q VD A L D
Sbjct: 752 GQ------QGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDD 805
Query: 619 E-LIAVKLREAEANL-SLKDLRQRVSELSESWQR-HLQEHKQEAPAAPVQSNVVSDIMAT 675
+ + +L AEA L K L Q++ E +E+ R H+QE Q + +D
Sbjct: 806 QDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQ 865
Query: 676 PKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQ 735
++ LRA + + EE ++ E +L EL QV T + R
Sbjct: 866 REEELRALQEELSQAKCSSEE---AQLEHAELQEQLHRANTDTAELGIQVCALTVEKERV 922
Query: 736 DEE-ARLLRENLDA--ALQRER--------ALQTRQREFQHKYADLESKA-KYESMQANI 783
+E A ++E DA A RER LQ + Q K ++ A +QA +
Sbjct: 923 EEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQL 982
Query: 784 RNMEDA----QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E Q A E +++L E+M + L+N + +L+EQ +L+A
Sbjct: 983 AQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAA 1042
Query: 840 IMRLEAWKS 848
+E K+
Sbjct: 1043 EEAVEKLKA 1051
Score = 36.3 bits (80), Expect = 0.48
Identities = 66/300 (22%), Positives = 112/300 (37%), Gaps = 25/300 (8%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEG-- 553
+V + +E LDRE Q LR A ++L + R T AE+N R + L
Sbjct: 243 EVREKQLQERMQQLDRENQELRAAVSQQGEQLQTERERGR----TAAEDNVRLTCLVAEL 298
Query: 554 -----TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQR 608
A+ +EL CLQ + L E ++ R
Sbjct: 299 QKQWEVTQATQNTVKELQTCLQALELGAAEKEEDYHTALRRLESMLQPLAQELEATR-DS 357
Query: 609 VDNNVAHLQD--ELIAVKLREAEANLSLK--------DLRQRVSELSESWQRHLQEHKQE 658
+D HL +A+ ++A++ K D Q + EL E Q +E +
Sbjct: 358 LDKKNQHLASFPGWLAMAQQKADSASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKV 417
Query: 659 APAAPVQSNVVSDIMATP--KKLLRA-WEGRSADMLKLDEELMTTRIREVEALTELKELR 715
QS + ++ K+ RA E +M L EEL + L+EL
Sbjct: 418 EEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELL 477
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK 775
E ++ + ++Q EE LL + + + ++ + L+T+ + +DLE + K
Sbjct: 478 AHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKK 537
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 51.2 bits (117), Expect = 2e-05
Identities = 99/473 (20%), Positives = 189/473 (39%), Gaps = 32/473 (6%)
Query: 399 KNDLLSLDMESILKYIQKE-LPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTK- 456
+ND LD + K + L K E +QA M L +K ++++LE+E +T
Sbjct: 11 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSR 70
Query: 457 ---EQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREV 513
E+ + R L + + L++ V Q R + EE T +
Sbjct: 71 AKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQHEATA 130
Query: 514 QALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELAR-CLQXX 572
LR+ + D L +D ++ ++ + E + +E + AS + A+ L+
Sbjct: 131 ATLRKKHADSVAELGEQIDNLQRVKQKL-EKEKSEMKMEIDDLASNMETVSKAKGNLEKM 189
Query: 573 XXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANL 632
I++L + L++ +V+ + + + + +L +
Sbjct: 190 CRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRGKQAF 249
Query: 633 S--LKDLRQRVSE--LSESWQRH-LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
+ +++L++++ E ++S H LQ + + Q + A +L RA +
Sbjct: 250 TQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKA---ELQRAMSKAN 306
Query: 688 ADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQVQ-VSTNQLRRQDEEARLLREN 745
+++ + + T I+ E L E K+L ++ + E V+ V+ + + RL E
Sbjct: 307 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEV 366
Query: 746 LDAALQRER------ALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEV 799
D + ER AL +Q F A E K K E A + + + R L TE+
Sbjct: 367 EDLMIDVERTNAACAALDKKQTNFDKILA--EWKQKCEETHAVLESFQKESR--SLSTEL 422
Query: 800 SEYKLKN---EVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSR 849
+K+KN E + L+ N + + +L EQ+AE I LE K +
Sbjct: 423 --FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 473
Score = 42.3 bits (95), Expect = 0.007
Identities = 63/340 (18%), Positives = 145/340 (42%), Gaps = 17/340 (5%)
Query: 512 EVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQX 571
+++ L+R N ++QQ ++ ++I I E + +E +S EE L+
Sbjct: 435 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEH 494
Query: 572 XXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEAN 631
I E + E ++R + + + ++R
Sbjct: 495 EEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHI--RIEESMQSTLNAEIRSRNDA 552
Query: 632 LSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADML 691
+ LK ++ +L+E + ++ A N + + T L A RS + L
Sbjct: 553 IRLK--KKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQLHLDDAL--RSQEDL 608
Query: 692 KLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQ 751
K ++ R ++A E++ELR + + E +++ +L E +LL + +
Sbjct: 609 KEQLAMVERRANLLQA--EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 666
Query: 752 RERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAE---LETEVSEY--KLKN 806
++ L+T + Q + D+ +A+ +A + + DA +AE E + S + ++K
Sbjct: 667 TKKKLETDISQIQGEMEDIIKEARNAEEKAK-KAITDAAMMAEELKKEQDTSAHLERMKK 725
Query: 807 EVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLE 844
+ T +L+ + +D++++ ++ ++Q+ +L+A++ LE
Sbjct: 726 NLEQTVKDLQ-HRLDEAEQLALKGGKKQIQKLEAKVRELE 764
Score = 37.1 bits (82), Expect = 0.28
Identities = 42/195 (21%), Positives = 97/195 (49%), Gaps = 26/195 (13%)
Query: 671 DIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVS-T 729
DI ++L + + +M L ++ + ++ ++KEL+ ++ ELE +++ T
Sbjct: 9 DIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERT 68
Query: 730 NQLRRQDEEARLLRENLDAALQRERAL----------QTRQREFQHKYADL-ESKAKYES 778
++ + + + L RE + + + E A+ + R+ EFQ DL E+ ++E+
Sbjct: 69 SRAKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQHEA 128
Query: 779 MQANIR------------NMEDAQRIAE-LETEVSEYKLKNEVMATEGELRNNNMDDSDR 825
A +R +++ QR+ + LE E SE K++ + +A+ E + + ++
Sbjct: 129 TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEK 188
Query: 826 V-RELQEQVAELKAE 839
+ R L++Q++E+K +
Sbjct: 189 MCRALEDQLSEIKTK 203
Score = 37.1 bits (82), Expect = 0.28
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 17/203 (8%)
Query: 597 LENENKSL--RRQRVDNNVAHLQDEL--IAVKLREAE--ANLSLKDLRQRVSELS--ESW 648
L +N SL +++++ +++ +Q E+ I + R AE A ++ D EL +
Sbjct: 657 LHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDT 716
Query: 649 QRHLQEHKQ--EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
HL+ K+ E +Q + K + + A + +L+ E+ + + R VE
Sbjct: 717 SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVE 776
Query: 707 ALTELKELRLKVMELETQVQVST-NQLRRQD------EEARLLRENLDAALQRERALQTR 759
A+ L + KV EL Q + N LR QD + + + + A ++ ++
Sbjct: 777 AVKGLHKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSK 836
Query: 760 QREFQHKYADLESKAKYESMQAN 782
R QH+ + E +A Q N
Sbjct: 837 FRRIQHELEEAEERADIAESQVN 859
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 74 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 130
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 131 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 190
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 191 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 250
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 251 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 303
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 304 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 337
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 51.2 bits (117), Expect = 2e-05
Identities = 76/347 (21%), Positives = 146/347 (42%), Gaps = 21/347 (6%)
Query: 510 DREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC- 568
D E+QALR + + + + V + E A R L+ + EEL R
Sbjct: 96 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 155
Query: 569 --LQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH--LQDELIAVK 624
LQ I +LE +R++ + A L++EL A +
Sbjct: 156 AQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHVRKEEKEAVSARRALENELEAAQ 215
Query: 625 LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWE 684
++ K L +++ E SE + L+ K E + ++ I K++ E
Sbjct: 216 GNLSQTTQEQKQLSEKLKEESEQ-KEQLRRLKNEMENE--RWHLGKTIEKLQKEMADIVE 272
Query: 685 GRSADMLKLDEELMTTRIREVEALTEL-KELRLKVMELETQVQVSTNQ---LRRQDEEAR 740
L+L +L + + L E+ ++L+ K +E E + +R +EE R
Sbjct: 273 ASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELR 332
Query: 741 LLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQAN-IRNMEDAQRIAELETEV 799
+ D AL + + L+ ++ ++ +LE+K+ + ++ ++ MED ++++LE E+
Sbjct: 333 DYQRAQDEALTKRQLLEQTLKDLEY---ELEAKSHLKDDRSRLVKQMED--KVSQLEMEL 387
Query: 800 SEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA--ELKAEIMRLE 844
E + N + TE R+ + R LQE+ A +L+ + + LE
Sbjct: 388 EEER-NNSDLLTERISRSREQMEQLRNELLQERAARQDLECDKISLE 433
Score = 48.4 bits (110), Expect = 1e-04
Identities = 70/358 (19%), Positives = 152/358 (42%), Gaps = 30/358 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEI-RSLEMTIAENNSRQSSLEGTESASGQK 561
+EE + D+E+ L+ Q L +++E +++E+ + +N+ + GTE
Sbjct: 78 KEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMR---- 133
Query: 562 HEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRR--QRVDNNVAHLQDE 619
+ LQ I++L+ + + ++ + + L++
Sbjct: 134 ----VKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEA 189
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
L+ V+ E EA + + L + + + QE KQ + +S + ++
Sbjct: 190 LVHVRKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEM 249
Query: 680 LRA-WE-GRSADMLKLD-----EELMTTRIREVEALTELKEL-RLKVMELETQVQVSTNQ 731
W G++ + L+ + E T+ + L E KE R ++ E++ Q++ T +
Sbjct: 250 ENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLE 309
Query: 732 LRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAK---YESMQANIRNMED 788
+ A +++ + + R Q Q E K LE K YE ++A +D
Sbjct: 310 AEKSRLTAMKMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYE-LEAKSHLKDD 368
Query: 789 AQRIA-ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
R+ ++E +VS+ +++ E E RNN+ ++R+ +EQ+ +L+ E+++ A
Sbjct: 369 RSRLVKQMEDKVSQLEMELE------EERNNSDLLTERISRSREQMEQLRNELLQERA 420
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 198 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 254
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 255 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDA 314
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 315 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 374
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 375 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 427
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 428 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 461
Score = 38.3 bits (85), Expect = 0.12
Identities = 31/147 (21%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 703 REVEALTELKELRL----KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+E+E LT+ E + K+ + + ++Q + L + R L NL+ ++ L
Sbjct: 49 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 108
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ KYAD +A+ E+ + + + A+ + E E + N+++ E E +
Sbjct: 109 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 168
Query: 819 NMDD-SDRVRELQEQVAELKAEIMRLE 844
+ DD V EL++ L+ ++ ++
Sbjct: 169 SKDDVGKNVHELEKSKRALETQMEEMK 195
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 51.2 bits (117), Expect = 2e-05
Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 34/277 (12%)
Query: 594 IDELENENKSLR--RQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
++ELE+E ++ + R++ N+ L+ + E N ++ R+++ ++
Sbjct: 198 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETE 254
Query: 652 LQ-EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS----------ADMLKLDEELMTT 700
L+ E KQ A AA + + D+ + A +GR A M EL
Sbjct: 255 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDA 314
Query: 701 RIREVEALTELKE-------LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
R E KE L +M+L+ + + ++ D E L E L ++L
Sbjct: 315 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 374
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 375 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 427
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 428 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 461
Score = 42.3 bits (95), Expect = 0.007
Identities = 78/362 (21%), Positives = 149/362 (41%), Gaps = 27/362 (7%)
Query: 501 EGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSR-QSSLEGTESASG 559
+ EE+ L R++ D +++ A+A + LE + + + S+++G E A
Sbjct: 236 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI- 294
Query: 560 QKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDE 619
KH R LQ E E + KSL + ++ LQ++
Sbjct: 295 -KH---VRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL-----EADLMQLQED 345
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
L A + +A+L ++L + ++ S S + LQ+ K+ A Q + + + +
Sbjct: 346 LAAAERARKQADLEKEELAEELAS-SLSGRNALQDEKRRLEARIAQ---LEEELEEEQGN 401
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEA 739
+ A R + E+L E + + R +LE Q + ++L +
Sbjct: 402 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR---QQLERQNKELRSKLHEMEGAV 458
Query: 740 RLLRENLDAALQRERALQTRQ--REFQHKYADLES-KAKYESMQANIRNMEDAQRIAELE 796
+ ++ AAL+ + A Q +E + K A +S K K + ++ + +ED +++AE
Sbjct: 459 KSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 518
Query: 797 TEVSEY------KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
E +E +LK ++ E E + N + REL E +A + A KS+
Sbjct: 519 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 578
Query: 851 LG 852
G
Sbjct: 579 RG 580
Score = 38.3 bits (85), Expect = 0.12
Identities = 31/147 (21%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 703 REVEALTELKELRL----KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
+E+E LT+ E + K+ + + ++Q + L + R L NL+ ++ L
Sbjct: 49 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 108
Query: 759 RQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN 818
++ KYAD +A+ E+ + + + A+ + E E + N+++ E E +
Sbjct: 109 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 168
Query: 819 NMDD-SDRVRELQEQVAELKAEIMRLE 844
+ DD V EL++ L+ ++ ++
Sbjct: 169 SKDDVGKNVHELEKSKRALETQMEEMK 195
>Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.
Length = 4684
Score = 50.8 bits (116), Expect = 2e-05
Identities = 80/363 (22%), Positives = 149/363 (41%), Gaps = 29/363 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E RSL + ++RQ L
Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEA 2179
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D L E ++ RR + A
Sbjct: 2180 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDRLRGEAEAARRAAEEAEEAR 2234
Query: 616 LQDELIAVK-LREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 2235 VQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 2288
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 2289 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2348
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 2349 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 2402
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWK 847
+ E E V+E + V A E LR +D + R L E++ + K + ++ EA +
Sbjct: 2403 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATR 2461
Query: 848 SRA 850
+A
Sbjct: 2462 LKA 2464
Score = 48.4 bits (110), Expect = 1e-04
Identities = 81/362 (22%), Positives = 147/362 (40%), Gaps = 36/362 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRL----AVALDEIRSLEMTIAENNSRQSSLEGT 554
R + EEE AL + +++ L + A D +RS E E +RQ L
Sbjct: 2057 RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAE 2115
Query: 555 ESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA 614
E ++ EE + ++E +SLR + +
Sbjct: 2116 EERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA----RSLRERAEQESAR 2171
Query: 615 HLQ-DELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
LQ + A K +AE ++Q+ EL ++ Q+ + +V+ +
Sbjct: 2172 QLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ--------------EQSVLDRLR 2217
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
+ RA E ++ + E +R R+VE LK+ + + Q Q + +LR
Sbjct: 2218 GEAEAARRAAEEAEEARVQAEREAAQSR-RQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2276
Query: 734 RQDEEARLLRENLDAALQRERALQTRQREFQHKYAD--LESKAKYESMQANIR-NMEDAQ 790
++ E+ R + A R++ + E K+A+ L KA+ E +R +E+
Sbjct: 2277 KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2336
Query: 791 RIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRVRELQEQVAELKAEIMRLEAWKSR 849
L E + +LK E ATE + + +++ VR E++++LKA R+EA ++R
Sbjct: 2337 HQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSVRVQMEELSKLKA---RIEA-ENR 2389
Query: 850 AL 851
AL
Sbjct: 2390 AL 2391
Score = 44.8 bits (101), Expect = 0.001
Identities = 57/280 (20%), Positives = 114/280 (40%), Gaps = 17/280 (6%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLRE-AEANLSLKDLRQR-VSELSESWQRHLQE 654
+E E + +QR + + E K R+ AEA+ K +R EL + Q +
Sbjct: 1481 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRIQEEVVR 1540
Query: 655 HKQEAPAAPVQSNVVSDIM--------ATPKKLLRAWEGRSADMLKLDEELMTTRIREVE 706
++ A A Q + + + A + R E L+++EE+ R++
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1600
Query: 707 ALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRER--ALQTRQREFQ 764
+ ++ L + + + Q R+ EEA LR + QR+R ++ R
Sbjct: 1601 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKA 1660
Query: 765 HKYADLESKAKYESMQANIRNMEDAQR-IAELETEVS---EYKLKNEVMATEGELRNNNM 820
A E + ++++ E+A+R + + E E + + L+ + E EL++
Sbjct: 1661 EAEAAREKQRALQALEELRLQAEEAERWLCQAEVERARQVQVALETAQRSAEAELQSKRA 1720
Query: 821 DDSDRVRELQEQVAELKAEIMRL-EAWKSRALGHTELSRA 859
+++ +L+ + E + +L E + RA E RA
Sbjct: 1721 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA 1760
Score = 41.1 bits (92), Expect = 0.017
Identities = 85/439 (19%), Positives = 179/439 (40%), Gaps = 43/439 (9%)
Query: 451 TVIKTKEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALD 510
T+ + +E+ +A + + RL + + Q +R E +E +
Sbjct: 1477 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER-EAKELQQRIQ 1535
Query: 511 REVQALRRANVDMQQRLAVALDEIRSLEMTI-AENNSRQSSLEGTESASGQKHEELARCL 569
EV A VD QQ+ +E++ L + AE ++ E E + + EE+ R +
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI-RVV 1594
Query: 570 QXXXXXXXXXXXXXXXXXXXXXXXIDELE-------NENKSLRRQRVDNNVAHLQDELIA 622
+ +E E E + LRRQ D + Q E+
Sbjct: 1595 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1654
Query: 623 VKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQ-SNVVSDIMATPKKLLR 681
+AEA + + +QR + E + +E ++ A V+ + V + T ++
Sbjct: 1655 ASRVKAEAEAARE--KQRALQALEELRLQAEEAERWLCQAEVERARQVQVALETAQRSAE 1712
Query: 682 A-WEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEAR 740
A + + A + +L + E A+ +L+E + + + + + + + RQ E +
Sbjct: 1713 AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERQLERWQ 1772
Query: 741 L-LRENLDAALQRERALQTR-----QREFQHKYADLESKAKYESMQANIRNMEDAQRIAE 794
L E L LQ E LQ + + E Q + A+ E++ + ++ + +R E A++ E
Sbjct: 1773 LKANEALRLRLQAEEVLQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1832
Query: 795 LETEVSEYKLKNEVMATE-----------GELRNNNMDD------------SDRVRELQE 831
+ +++E + + A + GE + +++ + + +EL+
Sbjct: 1833 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1892
Query: 832 QVAELKAEIMRLEAWKSRA 850
++A+++AE+ L A K++A
Sbjct: 1893 ELAKVRAEMEVLLASKAKA 1911
Score = 38.7 bits (86), Expect = 0.090
Identities = 76/369 (20%), Positives = 145/369 (39%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A+ EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 1908 KAKAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 1961
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 1962 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 2009
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 2010 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 2069
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 2070 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 2129
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R+L+ R + + L +A + +QA +
Sbjct: 2130 SLAAEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAEEK 2189
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 2190 AHAFAVQQKEQELQQTLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2249
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 2250 EAERLKQSA 2258
Score = 38.7 bits (86), Expect = 0.090
Identities = 71/436 (16%), Positives = 163/436 (37%), Gaps = 24/436 (5%)
Query: 408 ESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDIAVLRCL 467
E + K ++E +A+A+QAA + + +K KK ++ K + + ++ LR
Sbjct: 2273 EKLRKEAEQEAARRAQAEQAA-LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2331
Query: 468 RQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALRR--ANVDMQQ 525
+E K + R R++ EEE F++ +++ L + A ++ +
Sbjct: 2332 LEETDHQKNLLDEELQRLKAEATEAAR---QRSQVEEELFSVRVQMEELSKLKARIEAEN 2388
Query: 526 RLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXXXXXXX 585
R + D+ + + + E + + + +E AR Q
Sbjct: 2389 RALILRDKDNT-QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2447
Query: 586 XXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS 645
+ E R + + + Q EL + R + + + + Q+++E +
Sbjct: 2448 MLKEKMQAVQEAT-------RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEET 2498
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLK----LDEELMTTR 701
+ +QR L+ +Q ++ + +A + E + K + E+L T
Sbjct: 2499 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2558
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ E +T ++ L ++ + + + + + E L++ + +QT Q+
Sbjct: 2559 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2618
Query: 762 EFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
E + E++A +S + ++ +R E E E ++EV +
Sbjct: 2619 EQLLQ----ETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ 2674
Query: 822 DSDRVRELQEQVAELK 837
+E Q VA ++
Sbjct: 2675 QQQMEQERQRLVASME 2690
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 50.8 bits (116), Expect = 2e-05
Identities = 55/261 (21%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 594 IDELENENKSLRRQRV--DNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
+DE E + L+ ++V + + +++E++ ++ + ++ K + R++E S
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 652 LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTEL 711
++ K A Q ++SD+ KK + + KLD E + + E ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 712 KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
EL+L++ + E ++Q L R D+E L + AL+ RE Q + A+L+
Sbjct: 1079 DELKLQLAKKEEELQ---GALARGDDE----------TLHKNNALKV-VRELQAQIAELQ 1124
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQ 830
+ E N + ELE +E + + A + ELR + ++ + L+
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1184
Query: 831 EQVAELKAEIMRLEAWKSRAL 851
E+ +A+I + + AL
Sbjct: 1185 EETKNHEAQIQDMRQRHATAL 1205
Score = 50.0 bits (114), Expect = 4e-05
Identities = 68/372 (18%), Positives = 156/372 (41%), Gaps = 33/372 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSS-----------L 551
EEET + ++Q +R+ + + L+ L++ + + + +N + L
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 552 EGTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQ---- 607
+ ++ S K ++L +Q +EL+N + L
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 608 -RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQS 666
+ + A L+ +L + E +L R+ +L E + LQE ++E A +
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE-KNSLQEQQEEEEEA--RK 1360
Query: 667 NVVSDIMATPKKLLRAWEGRSADMLKLD--EELMTTRIREVEALTE-LKELRLKVMELE- 722
N+ ++A +L + D+ ++ EE +++ EAL++ L+E L +LE
Sbjct: 1361 NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEK 1420
Query: 723 --TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQ 780
++Q + L + R + NL+ ++ L ++ +YA+ +A+ E+ +
Sbjct: 1421 TKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 781 ANIRNMEDAQRIAELETEVSEYKLKN--------EVMATEGELRNNNMDDSDRVRELQEQ 832
+ + A+ + E E++ +N ++M+++ ++ N + R L++Q
Sbjct: 1481 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Query: 833 VAELKAEIMRLE 844
V E++ ++ LE
Sbjct: 1541 VEEMRTQLEELE 1552
Score = 41.1 bits (92), Expect = 0.017
Identities = 70/282 (24%), Positives = 131/282 (46%), Gaps = 36/282 (12%)
Query: 600 ENKSLRRQRVDNNVAHLQDEL--IAVKL---REAEANLSLKDLR--QRVSELSESWQRHL 652
E K+L +++ LQ EL + V L R+ +NL K + Q ++E R+
Sbjct: 1409 EEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYA 1468
Query: 653 QEH-KQEAPAAPVQSNVVSDIMATPKKLLRAWE-GRSADMLKLD-EELMTTR------IR 703
+E + EA A ++ +S A + L E R L+ D E+LM+++ +
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 704 EVE----ALTE-LKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDA-ALQRERAL 756
E+E AL + ++E+R ++ ELE ++Q + E+A+L L N+ A Q ER L
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLEELEDELQAT--------EDAKLRLEVNMQAMKAQFERDL 1580
Query: 757 QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELR 816
QTR + + K L + + ++A + + + +A + E LK+ + + E
Sbjct: 1581 QTRDEQNEEKKRLLIKQVR--ELEAELEDERKQRALAVASKKKMEIDLKD--LEAQIEAA 1636
Query: 817 NNNMDD-SDRVRELQEQVAELKAEIMRLEAWKSRALGHTELS 857
N D+ ++R+LQ Q+ + + E+ A + ++ S
Sbjct: 1637 NKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Score = 34.7 bits (76), Expect = 1.5
Identities = 33/145 (22%), Positives = 70/145 (48%), Gaps = 12/145 (8%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
DEEL+ + ++ + EL+E+ K +L + + QL+ + E L A +
Sbjct: 858 DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE--------LFAEAEEM 909
Query: 754 RA-LQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATE 812
RA L +++E + DLES+ + E + I E + A ++ E +L E A +
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD--LEEQLDEEEGARQ 967
Query: 813 GELRNNNMDDSDRVRELQEQVAELK 837
+L+ + ++++++E++ L+
Sbjct: 968 -KLQLEKVTAEAKIKKMEEEILLLE 991
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 50.8 bits (116), Expect = 2e-05
Identities = 55/261 (21%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 594 IDELENENKSLRRQRV--DNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
+DE E + L+ ++V + + +++E++ ++ + ++ K + R++E S
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 652 LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTEL 711
++ K A Q ++SD+ KK + + KLD E + + E ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 712 KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
EL+L++ + E ++Q L R D+E L + AL+ RE Q + A+L+
Sbjct: 1079 DELKLQLAKKEEELQ---GALARGDDE----------TLHKNNALKV-VRELQAQIAELQ 1124
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQ 830
+ E N + ELE +E + + A + ELR + ++ + L+
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1184
Query: 831 EQVAELKAEIMRLEAWKSRAL 851
E+ +A+I + + AL
Sbjct: 1185 EETKNHEAQIQDMRQRHATAL 1205
Score = 50.0 bits (114), Expect = 4e-05
Identities = 68/372 (18%), Positives = 156/372 (41%), Gaps = 33/372 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSS-----------L 551
EEET + ++Q +R+ + + L+ L++ + + + +N + L
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 552 EGTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQ---- 607
+ ++ S K ++L +Q +EL+N + L
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 608 -RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQS 666
+ + A L+ +L + E +L R+ +L E + LQE ++E A +
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE-KNSLQEQQEEEEEA--RK 1360
Query: 667 NVVSDIMATPKKLLRAWEGRSADMLKLD--EELMTTRIREVEALTE-LKELRLKVMELE- 722
N+ ++A +L + D+ ++ EE +++ EAL++ L+E L +LE
Sbjct: 1361 NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEK 1420
Query: 723 --TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQ 780
++Q + L + R + NL+ ++ L ++ +YA+ +A+ E+ +
Sbjct: 1421 TKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 781 ANIRNMEDAQRIAELETEVSEYKLKN--------EVMATEGELRNNNMDDSDRVRELQEQ 832
+ + A+ + E E++ +N ++M+++ ++ N + R L++Q
Sbjct: 1481 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Query: 833 VAELKAEIMRLE 844
V E++ ++ LE
Sbjct: 1541 VEEMRTQLEELE 1552
Score = 41.1 bits (92), Expect = 0.017
Identities = 70/282 (24%), Positives = 131/282 (46%), Gaps = 36/282 (12%)
Query: 600 ENKSLRRQRVDNNVAHLQDEL--IAVKL---REAEANLSLKDLR--QRVSELSESWQRHL 652
E K+L +++ LQ EL + V L R+ +NL K + Q ++E R+
Sbjct: 1409 EEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYA 1468
Query: 653 QEH-KQEAPAAPVQSNVVSDIMATPKKLLRAWE-GRSADMLKLD-EELMTTR------IR 703
+E + EA A ++ +S A + L E R L+ D E+LM+++ +
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 704 EVE----ALTE-LKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDA-ALQRERAL 756
E+E AL + ++E+R ++ ELE ++Q + E+A+L L N+ A Q ER L
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLEELEDELQAT--------EDAKLRLEVNMQAMKAQFERDL 1580
Query: 757 QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELR 816
QTR + + K L + + ++A + + + +A + E LK+ + + E
Sbjct: 1581 QTRDEQNEEKKRLLIKQVR--ELEAELEDERKQRALAVASKKKMEIDLKD--LEAQIEAA 1636
Query: 817 NNNMDD-SDRVRELQEQVAELKAEIMRLEAWKSRALGHTELS 857
N D+ ++R+LQ Q+ + + E+ A + ++ S
Sbjct: 1637 NKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Score = 34.7 bits (76), Expect = 1.5
Identities = 33/145 (22%), Positives = 70/145 (48%), Gaps = 12/145 (8%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
DEEL+ + ++ + EL+E+ K +L + + QL+ + E L A +
Sbjct: 858 DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE--------LFAEAEEM 909
Query: 754 RA-LQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATE 812
RA L +++E + DLES+ + E + I E + A ++ E +L E A +
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD--LEEQLDEEEGARQ 967
Query: 813 GELRNNNMDDSDRVRELQEQVAELK 837
+L+ + ++++++E++ L+
Sbjct: 968 -KLQLEKVTAEAKIKKMEEEILLLE 991
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 50.8 bits (116), Expect = 2e-05
Identities = 55/261 (21%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 594 IDELENENKSLRRQRV--DNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
+DE E + L+ ++V + + +++E++ ++ + ++ K + R++E S
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 652 LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTEL 711
++ K A Q ++SD+ KK + + KLD E + + E ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 712 KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
EL+L++ + E ++Q L R D+E L + AL+ RE Q + A+L+
Sbjct: 1079 DELKLQLAKKEEELQ---GALARGDDE----------TLHKNNALKV-VRELQAQIAELQ 1124
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQ 830
+ E N + ELE +E + + A + ELR + ++ + L+
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1184
Query: 831 EQVAELKAEIMRLEAWKSRAL 851
E+ +A+I + + AL
Sbjct: 1185 EETKNHEAQIQDMRQRHATAL 1205
Score = 50.0 bits (114), Expect = 4e-05
Identities = 68/372 (18%), Positives = 156/372 (41%), Gaps = 33/372 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSS-----------L 551
EEET + ++Q +R+ + + L+ L++ + + + +N + L
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 552 EGTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQ---- 607
+ ++ S K ++L +Q +EL+N + L
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 608 -RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQS 666
+ + A L+ +L + E +L R+ +L E + LQE ++E A +
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE-KNSLQEQQEEEEEA--RK 1360
Query: 667 NVVSDIMATPKKLLRAWEGRSADMLKLD--EELMTTRIREVEALTE-LKELRLKVMELE- 722
N+ ++A +L + D+ ++ EE +++ EAL++ L+E L +LE
Sbjct: 1361 NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEK 1420
Query: 723 --TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQ 780
++Q + L + R + NL+ ++ L ++ +YA+ +A+ E+ +
Sbjct: 1421 TKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 781 ANIRNMEDAQRIAELETEVSEYKLKN--------EVMATEGELRNNNMDDSDRVRELQEQ 832
+ + A+ + E E++ +N ++M+++ ++ N + R L++Q
Sbjct: 1481 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Query: 833 VAELKAEIMRLE 844
V E++ ++ LE
Sbjct: 1541 VEEMRTQLEELE 1552
Score = 38.3 bits (85), Expect = 0.12
Identities = 69/282 (24%), Positives = 130/282 (46%), Gaps = 36/282 (12%)
Query: 600 ENKSLRRQRVDNNVAHLQDEL--IAVKL---REAEANLSLKDLR--QRVSELSESWQRHL 652
E K+L +++ LQ E + V L R+ +NL K + Q ++E R+
Sbjct: 1409 EEKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYA 1468
Query: 653 QEH-KQEAPAAPVQSNVVSDIMATPKKLLRAWE-GRSADMLKLD-EELMTTR------IR 703
+E + EA A ++ +S A + L E R L+ D E+LM+++ +
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 704 EVE----ALTE-LKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDA-ALQRERAL 756
E+E AL + ++E+R ++ ELE ++Q + E+A+L L N+ A Q ER L
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLEELEDELQAT--------EDAKLRLEVNMQAMKAQFERDL 1580
Query: 757 QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELR 816
QTR + + K L + + ++A + + + +A + E LK+ + + E
Sbjct: 1581 QTRDEQNEEKKRLLIKQVR--ELEAELEDERKQRALAVASKKKMEIDLKD--LEAQIEAA 1636
Query: 817 NNNMDD-SDRVRELQEQVAELKAEIMRLEAWKSRALGHTELS 857
N D+ ++R+LQ Q+ + + E+ A + ++ S
Sbjct: 1637 NKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Score = 34.7 bits (76), Expect = 1.5
Identities = 33/145 (22%), Positives = 70/145 (48%), Gaps = 12/145 (8%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
DEEL+ + ++ + EL+E+ K +L + + QL+ + E L A +
Sbjct: 858 DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE--------LFAEAEEM 909
Query: 754 RA-LQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATE 812
RA L +++E + DLES+ + E + I E + A ++ E +L E A +
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD--LEEQLDEEEGARQ 967
Query: 813 GELRNNNMDDSDRVRELQEQVAELK 837
+L+ + ++++++E++ L+
Sbjct: 968 -KLQLEKVTAEAKIKKMEEEILLLE 991
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 50.8 bits (116), Expect = 2e-05
Identities = 55/261 (21%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 594 IDELENENKSLRRQRV--DNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
+DE E + L+ ++V + + +++E++ ++ + ++ K + R++E S
Sbjct: 1001 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1060
Query: 652 LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTEL 711
++ K A Q ++SD+ KK + + KLD E + + E ++
Sbjct: 1061 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1120
Query: 712 KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
EL+L++ + E ++Q L R D+E L + AL+ RE Q + A+L+
Sbjct: 1121 DELKLQLAKKEEELQ---GALARGDDE----------TLHKNNALKV-VRELQAQIAELQ 1166
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQ 830
+ E N + ELE +E + + A + ELR + ++ + L+
Sbjct: 1167 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1226
Query: 831 EQVAELKAEIMRLEAWKSRAL 851
E+ +A+I + + AL
Sbjct: 1227 EETKNHEAQIQDMRQRHATAL 1247
Score = 50.0 bits (114), Expect = 4e-05
Identities = 68/372 (18%), Positives = 156/372 (41%), Gaps = 33/372 (8%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSS-----------L 551
EEET + ++Q +R+ + + L+ L++ + + + +N + L
Sbjct: 1226 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1285
Query: 552 EGTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQ---- 607
+ ++ S K ++L +Q +EL+N + L
Sbjct: 1286 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1345
Query: 608 -RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQS 666
+ + A L+ +L + E +L R+ +L E + LQE ++E A +
Sbjct: 1346 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE-KNSLQEQQEEEEEA--RK 1402
Query: 667 NVVSDIMATPKKLLRAWEGRSADMLKLD--EELMTTRIREVEALTE-LKELRLKVMELE- 722
N+ ++A +L + D+ ++ EE +++ EAL++ L+E L +LE
Sbjct: 1403 NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEK 1462
Query: 723 --TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQ 780
++Q + L + R + NL+ ++ L ++ +YA+ +A+ E+ +
Sbjct: 1463 TKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1522
Query: 781 ANIRNMEDAQRIAELETEVSEYKLKN--------EVMATEGELRNNNMDDSDRVRELQEQ 832
+ + A+ + E E++ +N ++M+++ ++ N + R L++Q
Sbjct: 1523 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1582
Query: 833 VAELKAEIMRLE 844
V E++ ++ LE
Sbjct: 1583 VEEMRTQLEELE 1594
Score = 41.1 bits (92), Expect = 0.017
Identities = 70/282 (24%), Positives = 131/282 (46%), Gaps = 36/282 (12%)
Query: 600 ENKSLRRQRVDNNVAHLQDEL--IAVKL---REAEANLSLKDLR--QRVSELSESWQRHL 652
E K+L +++ LQ EL + V L R+ +NL K + Q ++E R+
Sbjct: 1451 EEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYA 1510
Query: 653 QEH-KQEAPAAPVQSNVVSDIMATPKKLLRAWE-GRSADMLKLD-EELMTTR------IR 703
+E + EA A ++ +S A + L E R L+ D E+LM+++ +
Sbjct: 1511 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1570
Query: 704 EVE----ALTE-LKELRLKVMELETQVQVSTNQLRRQDEEARL-LRENLDA-ALQRERAL 756
E+E AL + ++E+R ++ ELE ++Q + E+A+L L N+ A Q ER L
Sbjct: 1571 ELEKSKRALEQQVEEMRTQLEELEDELQAT--------EDAKLRLEVNMQAMKAQFERDL 1622
Query: 757 QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELR 816
QTR + + K L + + ++A + + + +A + E LK+ + + E
Sbjct: 1623 QTRDEQNEEKKRLLIKQVR--ELEAELEDERKQRALAVASKKKMEIDLKD--LEAQIEAA 1678
Query: 817 NNNMDD-SDRVRELQEQVAELKAEIMRLEAWKSRALGHTELS 857
N D+ ++R+LQ Q+ + + E+ A + ++ S
Sbjct: 1679 NKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1720
Score = 34.7 bits (76), Expect = 1.5
Identities = 33/145 (22%), Positives = 70/145 (48%), Gaps = 12/145 (8%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
DEEL+ + ++ + EL+E+ K +L + + QL+ + E L A +
Sbjct: 900 DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE--------LFAEAEEM 951
Query: 754 RA-LQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATE 812
RA L +++E + DLES+ + E + I E + A ++ E +L E A +
Sbjct: 952 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD--LEEQLDEEEGARQ 1009
Query: 813 GELRNNNMDDSDRVRELQEQVAELK 837
+L+ + ++++++E++ L+
Sbjct: 1010 -KLQLEKVTAEAKIKKMEEEILLLE 1033
>BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein.
Length = 1193
Score = 50.4 bits (115), Expect = 3e-05
Identities = 64/228 (28%), Positives = 106/228 (46%), Gaps = 24/228 (10%)
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKK 678
EL ++ EA L++LRQ V +L E + +EH A + QS T K
Sbjct: 157 ELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEH---ASGSGAQSEAAGRTEPTGPK 213
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
L E A++ KL+++ + + L+ R E ++ ++ QL + +E
Sbjct: 214 L----EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQE 269
Query: 739 ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQR----IAE 794
+ L A+ QRE A F+ K D SKA+ E R ++A+R I+
Sbjct: 270 LGHSQSAL-ASAQRELA------AFRTKVQD-HSKAEDEWKAQVARGRQEAERKNSLISS 321
Query: 795 LETEVSEYKLKNEVMATEG---ELRNNNMDDSDRVRELQEQVAELKAE 839
LE EVS L +V+ EG EL+ M +S++ ++L+E++ L+AE
Sbjct: 322 LEEEVS--ILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAE 367
Score = 37.5 bits (83), Expect = 0.21
Identities = 74/420 (17%), Positives = 159/420 (37%), Gaps = 30/420 (7%)
Query: 456 KEQGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA 515
+ Q D+A+ + R E + Q + + EG+++ A R ++A
Sbjct: 107 RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 166
Query: 516 LRRANVD-MQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXX 574
+ ++ ++Q + +++ E A + QS G +G K E L +
Sbjct: 167 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRA--EVSKL 224
Query: 575 XXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSL 634
+ + + + + EL + A A L
Sbjct: 225 EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQREL 284
Query: 635 KDLRQRV---SELSESWQRHLQEHKQEAPAA-PVQSNVVSDIMATPKKLLRAWEGRSADM 690
R +V S+ + W+ + +QEA + S++ ++ +++L EG S ++
Sbjct: 285 AAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEK-EGESKEL 343
Query: 691 LKL------DEELMTTRIREVEALTELKELRL--KVMELETQVQVSTNQLRRQDEEARLL 742
+L + + R+R ++A T R + L +VQ + +Q + L
Sbjct: 344 KRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENL 403
Query: 743 RENLDAALQRERALQTRQREFQHKYADLES-----KAKYESMQANIRNMEDAQRIA---E 794
R+ L + +R L + +Q K+ E + ++ S QA + + A+ + +
Sbjct: 404 RQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQ 463
Query: 795 LETEVSEYKLKNEVMATE---GELRNNNMDDSDRVRE---LQEQVAELKAEIMRLEAWKS 848
E +E + + E+ ++ G LR + + E L+++VAE + +L A K+
Sbjct: 464 AEQAAAEKRHREELEQSKQAAGALRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKA 523
Score = 35.5 bits (78), Expect = 0.84
Identities = 47/236 (19%), Positives = 104/236 (44%), Gaps = 12/236 (5%)
Query: 630 ANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRA-WEGRSA 688
ANL + L + + E + + L + +A + + A +++ A +EG
Sbjct: 550 ANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV 609
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR---RQDEEARLLREN 745
+L EE + + +++EL K+ + + +V +L+ Q E++ +
Sbjct: 610 KVL---EERQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR 666
Query: 746 LDAALQRERA-LQTRQREFQHKYADLE-SKAKYES-MQANIRNMEDAQRIAELETEVSEY 802
L A L +A L +++ +H +E +K Y++ Q N E + + +L+ E E
Sbjct: 667 LQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKEL 726
Query: 803 KLKNEVMATEGELRNNNMDDSDRV-RELQEQVAELKAEIMRLEAWKSRALGHTELS 857
+ + E + E + ++++ R L QV L+A++ + + R LG +++
Sbjct: 727 RAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ-QLRDLGKFQVA 781
Score = 34.3 bits (75), Expect = 1.9
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 16/157 (10%)
Query: 703 REVEAL-TELKELRLKVMELETQVQVSTNQLRRQDEEARLLRE--NLDAALQRERALQTR 759
RE E + EL+ LR +ME + Q Q Q R E ARL +E A L E+A +
Sbjct: 64 REAEQMGNELERLRAALMESQGQQQEERGQQER--EVARLTQERGRAQADLALEKAARA- 120
Query: 760 QREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY-KLKNEVMATEGELRNN 818
+ E + + A E + ++ ++Q + A + E E + E KL+ A EL
Sbjct: 121 ELEMRLQNALNEQRVEFATLQEAL-----AHALTEKEGKDQELAKLRGLEAAQIKELE-- 173
Query: 819 NMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
+ V++L+EQ+A+ + E +S A G TE
Sbjct: 174 --ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTE 208
>AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protein
130d protein.
Length = 1135
Score = 50.4 bits (115), Expect = 3e-05
Identities = 89/468 (19%), Positives = 193/468 (41%), Gaps = 42/468 (8%)
Query: 402 LLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI 461
LL + E + K I +E+ + E +Q K++ L++E T +K+ +
Sbjct: 195 LLEQECERLKKLIDQEIKSQEEKEQE-----------KEKRVTTLKEELTKLKSFALMVV 243
Query: 462 AVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA-LRRAN 520
+ L + L +Q++ + E E++ L++E+Q + +
Sbjct: 244 DEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFH 303
Query: 521 VDMQQRLAVALDEI---RSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
D +A +E R L+ +A + + LE T + + EEL +
Sbjct: 304 QDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+D +E +++ L + ++ L L L+ + L ++ L
Sbjct: 364 GNAGIMAEVEELRKRVLD-MEGKDEELIK--MEEQCRDLNKRLERETLQSKDFKLEVEKL 420
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK--KLLRAWEGRSADMLKLDE 695
+R+ L E + + KQE + ++ N+ + M T + + L + + R ++ ++
Sbjct: 421 SKRIMAL-EKLEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRIKELEAIES 477
Query: 696 ELMTTRIREVEALTELKELRL-----------KVMELETQVQVSTNQLRRQDEEARLLRE 744
L T E LT+LK L + K+ + E ++Q +++QL+ + + + E
Sbjct: 478 RLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTE 537
Query: 745 NL----DAALQRERALQTRQREFQHKYADLESKAKYESMQAN---IRNMEDAQRIAELET 797
L AL+ + ++ + + DL++K K E + N R R+ LE
Sbjct: 538 KLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEA 597
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
++ LKN++ G+ ++++++EL ++V LK ++ ++A
Sbjct: 598 IEKDF-LKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKA 644
>AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 720
Score = 50.4 bits (115), Expect = 3e-05
Identities = 57/264 (21%), Positives = 120/264 (45%), Gaps = 21/264 (7%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHK 656
L+ + + L+++ + N L+D KL + + L + +QR S +E ++ ++ +
Sbjct: 468 LQQQQQMLQQETIRNG--ELEDT--QTKLEKQVSKLEQELQKQRESS-AEKLRKMEEKCE 522
Query: 657 QEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL 716
A A ++ V ++ T +++ + ++ K+++E+M + L +L +
Sbjct: 523 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDM 582
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
+ + +T+++ TN ++ ++ L ALQ+ L+T E Q+ + +L+S +
Sbjct: 583 ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLET---ELQNAHGELKSTLR- 638
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAEL 836
++ + D + A+L E +Y ++ A ELR M+ D+ +EL E L
Sbjct: 639 -----QLQELRDVLQKAQLSLE-EKYTTIKDLTA---ELRECKMEIEDKKQELLEMDQAL 689
Query: 837 KAEIMRLEAWKSRALGHTELSRAI 860
K L K RA T L I
Sbjct: 690 KERNWEL---KQRAAQVTHLDMTI 710
Score = 35.5 bits (78), Expect = 0.84
Identities = 24/172 (13%), Positives = 80/172 (46%), Gaps = 6/172 (3%)
Query: 677 KKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQD 736
++L+ E +++++ E ++ ++ + ++ +++E + +++ ++
Sbjct: 238 QRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKC 297
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+ L + L+ + ++ + E + +L +A+ E + E + + +
Sbjct: 298 SQLLTLEKQLEEKIVAYSSIAAKNAELEQ---ELMLEAQLEKKDQQFKEQEKTMSMLQQD 354
Query: 797 TEVSEYKLKN-EVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
++ L++ + + TE GE++ NM + ++ LQ QV+E ++ +L++
Sbjct: 355 IICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDS 406
Score = 35.1 bits (77), Expect = 1.1
Identities = 43/217 (19%), Positives = 96/217 (44%), Gaps = 18/217 (8%)
Query: 621 IAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLL 680
IA K E E L L+ ++ + + ++ + +Q+ + ++ K +
Sbjct: 317 IAAKNAELEQELMLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEM 376
Query: 681 RAWEGRSADMLK-LDEELM--TTRIREVEALTEL--KELRLKVMELETQVQVSTNQLRRQ 735
+ + + LK L ++ T ++R++++ E+ +EL L + +LE + QL+++
Sbjct: 377 KKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKK 436
Query: 736 DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAEL 795
EE L++ L + + QH + + E+ IRN EL
Sbjct: 437 SEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQET----IRN-------GEL 485
Query: 796 ETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
E ++ KL+ +V E EL+ ++++R+++E+
Sbjct: 486 ED--TQTKLEKQVSKLEQELQKQRESSAEKLRKMEEK 520
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 50.4 bits (115), Expect = 3e-05
Identities = 57/264 (21%), Positives = 120/264 (45%), Gaps = 21/264 (7%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHK 656
L+ + + L+++ + N L+D KL + + L + +QR S +E ++ ++ +
Sbjct: 538 LQQQQQMLQQETIRNG--ELEDT--QTKLEKQVSKLEQELQKQRESS-AEKLRKMEEKCE 592
Query: 657 QEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL 716
A A ++ V ++ T +++ + ++ K+++E+M + L +L +
Sbjct: 593 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDM 652
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
+ + +T+++ TN ++ ++ L ALQ+ L+T E Q+ + +L+S +
Sbjct: 653 ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLET---ELQNAHGELKSTLR- 708
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAEL 836
++ + D + A+L E +Y ++ A ELR M+ D+ +EL E L
Sbjct: 709 -----QLQELRDVLQKAQLSLE-EKYTTIKDLTA---ELRECKMEIEDKKQELLEMDQAL 759
Query: 837 KAEIMRLEAWKSRALGHTELSRAI 860
K L K RA T L I
Sbjct: 760 KERNWEL---KQRAAQVTHLDMTI 780
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/161 (18%), Positives = 72/161 (44%), Gaps = 4/161 (2%)
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
++M K +L+T + E + + K ELE ++ ++R + E +
Sbjct: 317 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKIC 376
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKN- 806
A ++ + + Q + K + +A+ E + E + + + ++ L++
Sbjct: 377 LAFEKAKKIHLEQHKEMEKQIE-RLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESL 435
Query: 807 EVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
+ + TE GE++ NM + ++ LQ QV+E ++ +L++
Sbjct: 436 DRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDS 476
Score = 40.7 bits (91), Expect = 0.022
Identities = 53/252 (21%), Positives = 113/252 (44%), Gaps = 29/252 (11%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
EL +N+ +R + N H + L K ++ K++ +++ L ++ Q+
Sbjct: 353 ELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQH-KEMEKQIERLEAQLEKKDQQF 411
Query: 656 K-QEAPAAPVQSNVV--SDIMATPKKLLRAWEGR-SADMLKLDEELM---------TTRI 702
K QE + +Q +++ + + +LL +G + +K DE L T ++
Sbjct: 412 KEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKV 471
Query: 703 REVEALTEL--KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ 760
R++++ E+ +EL L + +LE + QL+++ EE L++ L + +
Sbjct: 472 RQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQN 531
Query: 761 REFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM 820
QH + + E+ IRN ELE ++ KL+ +V E EL+
Sbjct: 532 VILQHTLQQQQQMLQQET----IRN-------GELED--TQTKLEKQVSKLEQELQKQRE 578
Query: 821 DDSDRVRELQEQ 832
++++R+++E+
Sbjct: 579 SSAEKLRKMEEK 590
Score = 38.3 bits (85), Expect = 0.12
Identities = 54/245 (22%), Positives = 100/245 (40%), Gaps = 27/245 (11%)
Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEA 659
E L + + + L D+L K + E + Q +S+L + +R Q K+
Sbjct: 799 EKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEME 858
Query: 660 PAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVM 719
Q + AT K + + L +EL TR + + TEL E R + +
Sbjct: 859 SVMKEQEQYI----ATQYK----------EAIDLGQELRLTREQVQNSHTELAEARHQQV 904
Query: 720 ELETQVQVSTNQL-------RRQDEEARLLRENLDAALQRERALQTR-QREFQHKYADLE 771
+ + +++ +++L + +D L E L A+ RE L+ R Q E + A++E
Sbjct: 905 QAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVE 964
Query: 772 S-KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQ 830
S K Y + + +I+ + S +L ++ + EL + D V L
Sbjct: 965 SLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELE----EAQDTVSNLH 1020
Query: 831 EQVAE 835
+QV +
Sbjct: 1021 QQVQD 1025
Score = 35.1 bits (77), Expect = 1.1
Identities = 59/352 (16%), Positives = 144/352 (40%), Gaps = 19/352 (5%)
Query: 504 EETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHE 563
EE + L +E++ + + ++ + ++ + + + R LE T++ ++
Sbjct: 508 EEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVS 567
Query: 564 ELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLR--RQRVDNNVAHLQDELI 621
+L + LQ D + L ++V + ++EL
Sbjct: 568 KLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELS 627
Query: 622 AVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLR 681
++ ++ +S+L + E +++ A + + L+
Sbjct: 628 KMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ 687
Query: 682 AWEGRSADMLKLDEELMTTRIREVEALTE-LKELRLKVMELETQVQVSTNQLRR-----Q 735
E ++ EL +T +R+++ L + L++ +L + E T ++ T +LR +
Sbjct: 688 KREVLETELQNAHGELKST-LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIE 746
Query: 736 DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAEL 795
D++ LL +D AL +ER + +QR Q + D+ + M+ I +E +EL
Sbjct: 747 DKKQELLE--MDQAL-KERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL 803
Query: 796 ETEVSEYKLKNEVMATEGELRNNNMDDSDR---VRELQEQVAELKAEIMRLE 844
E + + ++ + +L+N ++ + + ++++++LK EI R +
Sbjct: 804 ELK----ECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQ 851
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 50.4 bits (115), Expect = 3e-05
Identities = 57/264 (21%), Positives = 120/264 (45%), Gaps = 21/264 (7%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHK 656
L+ + + L+++ + N L+D KL + + L + +QR S +E ++ ++ +
Sbjct: 792 LQQQQQMLQQETIRNG--ELEDT--QTKLEKQVSKLEQELQKQRESS-AEKLRKMEEKCE 846
Query: 657 QEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL 716
A A ++ V ++ T +++ + ++ K+++E+M + L +L +
Sbjct: 847 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDM 906
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
+ + +T+++ TN ++ ++ L ALQ+ L+T E Q+ + +L+S +
Sbjct: 907 ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLET---ELQNAHGELKSTLR- 962
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAEL 836
++ + D + A+L E +Y ++ A ELR M+ D+ +EL E L
Sbjct: 963 -----QLQELRDVLQKAQLSLE-EKYTTIKDLTA---ELRECKMEIEDKKQELLEMDQAL 1013
Query: 837 KAEIMRLEAWKSRALGHTELSRAI 860
K L K RA T L I
Sbjct: 1014 KERNWEL---KQRAAQVTHLDMTI 1034
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/161 (18%), Positives = 72/161 (44%), Gaps = 4/161 (2%)
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
++M K +L+T + E + + K ELE ++ ++R + E +
Sbjct: 571 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKIC 630
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKN- 806
A ++ + + Q + K + +A+ E + E + + + ++ L++
Sbjct: 631 LAFEKAKKIHLEQHKEMEKQIE-RLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESL 689
Query: 807 EVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
+ + TE GE++ NM + ++ LQ QV+E ++ +L++
Sbjct: 690 DRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDS 730
Score = 44.0 bits (99), Expect = 0.002
Identities = 61/265 (23%), Positives = 112/265 (42%), Gaps = 33/265 (12%)
Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEA 659
E L + + + L D+L K + E + Q +S+L + +R Q K+
Sbjct: 1053 EKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEME 1112
Query: 660 PAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVM 719
Q + AT K + + L +EL TR + + TEL E R + +
Sbjct: 1113 SVMKEQEQYI----ATQYK----------EAIDLGQELRLTREQVQNSHTELAEARHQQV 1158
Query: 720 ELETQVQVSTNQL-------RRQDEEARLLRENLDAALQRERALQTR-QREFQHKYADLE 771
+ + +++ +++L + +D L E L A+ RE L+ R Q E + A++E
Sbjct: 1159 QAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVE 1218
Query: 772 S-KAKYE----SMQANIRNME---DAQR--IAELETEVSEYKLK-NEVMATEGELRNNNM 820
S K Y S Q N + D+Q+ + +L ++ + KL+ E T L
Sbjct: 1219 SLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQ 1278
Query: 821 DDSDRVRELQEQVAELKAEIMRLEA 845
D ++ + E + ++E+ RL+A
Sbjct: 1279 DRNEVIEAANEALLTKESELTRLQA 1303
Score = 40.7 bits (91), Expect = 0.022
Identities = 53/252 (21%), Positives = 113/252 (44%), Gaps = 29/252 (11%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
EL +N+ +R + N H + L K ++ K++ +++ L ++ Q+
Sbjct: 607 ELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQH-KEMEKQIERLEAQLEKKDQQF 665
Query: 656 K-QEAPAAPVQSNVV--SDIMATPKKLLRAWEGR-SADMLKLDEELM---------TTRI 702
K QE + +Q +++ + + +LL +G + +K DE L T ++
Sbjct: 666 KEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKV 725
Query: 703 REVEALTEL--KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ 760
R++++ E+ +EL L + +LE + QL+++ EE L++ L + +
Sbjct: 726 RQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQN 785
Query: 761 REFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM 820
QH + + E+ IRN ELE ++ KL+ +V E EL+
Sbjct: 786 VILQHTLQQQQQMLQQET----IRN-------GELED--TQTKLEKQVSKLEQELQKQRE 832
Query: 821 DDSDRVRELQEQ 832
++++R+++E+
Sbjct: 833 SSAEKLRKMEEK 844
Score = 38.3 bits (85), Expect = 0.12
Identities = 48/231 (20%), Positives = 105/231 (45%), Gaps = 14/231 (6%)
Query: 612 NVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHK--QEAPAAPVQSNVV 669
+V L++++I + EAE + K LR+ ++L +S + +++ + QE+ ++ V
Sbjct: 167 SVPILEEQIINL---EAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKV- 222
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVST 729
D++ K+ RA R+ + +E + + + +L++++ + LE +
Sbjct: 223 -DLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCE 281
Query: 730 NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDA 789
+ +R E L + L+ ++ R L+ + K + K + A + E
Sbjct: 282 KENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMA--VKNSEVMAQLT--ESR 337
Query: 790 QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
Q I +LE+E+ K+E++ + L N N + RV E++ + EI
Sbjct: 338 QSILKLESELEN---KDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEI 385
Score = 35.1 bits (77), Expect = 1.1
Identities = 59/352 (16%), Positives = 144/352 (40%), Gaps = 19/352 (5%)
Query: 504 EETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHE 563
EE + L +E++ + + ++ + ++ + + + R LE T++ ++
Sbjct: 762 EEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVS 821
Query: 564 ELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLR--RQRVDNNVAHLQDELI 621
+L + LQ D + L ++V + ++EL
Sbjct: 822 KLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELS 881
Query: 622 AVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLR 681
++ ++ +S+L + E +++ A + + L+
Sbjct: 882 KMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ 941
Query: 682 AWEGRSADMLKLDEELMTTRIREVEALTE-LKELRLKVMELETQVQVSTNQLRR-----Q 735
E ++ EL +T +R+++ L + L++ +L + E T ++ T +LR +
Sbjct: 942 KREVLETELQNAHGELKST-LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIE 1000
Query: 736 DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAEL 795
D++ LL +D AL +ER + +QR Q + D+ + M+ I +E +EL
Sbjct: 1001 DKKQELLE--MDQAL-KERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL 1057
Query: 796 ETEVSEYKLKNEVMATEGELRNNNMDDSDR---VRELQEQVAELKAEIMRLE 844
E + + ++ + +L+N ++ + + ++++++LK EI R +
Sbjct: 1058 ELK----ECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQ 1105
Score = 34.7 bits (76), Expect = 1.5
Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 736 DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAEL 795
D+E + LRE L+ Q+ L T+ K+ + + +A + +E AQ+ A
Sbjct: 110 DQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIH--FELTQSRAKVSMLESAQQQAAS 167
Query: 796 ETEVSE--YKLKNEVMATEGELR--NNNMDDSDR-VRELQEQVAELKAEIMRLE 844
+ E L+ EV A + LR N ++ S + V E ++ + E K E ++L+
Sbjct: 168 VPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLK 221
>AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protein
130c protein.
Length = 1133
Score = 50.4 bits (115), Expect = 3e-05
Identities = 89/468 (19%), Positives = 193/468 (41%), Gaps = 42/468 (8%)
Query: 402 LLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI 461
LL + E + K I +E+ + E +Q K++ L++E T +K+ +
Sbjct: 195 LLEQECERLKKLIDQEIKSQEEKEQE-----------KEKRVTTLKEELTKLKSFALMVV 243
Query: 462 AVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA-LRRAN 520
+ L + L +Q++ + E E++ L++E+Q + +
Sbjct: 244 DEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFH 303
Query: 521 VDMQQRLAVALDEI---RSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
D +A +E R L+ +A + + LE T + + EEL +
Sbjct: 304 QDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+D +E +++ L + ++ L L L+ + L ++ L
Sbjct: 364 GNAGIMAEVEELRKRVLD-MEGKDEELIK--MEEQCRDLNKRLERETLQSKDFKLEVEKL 420
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK--KLLRAWEGRSADMLKLDE 695
+R+ L E + + KQE + ++ N+ + M T + + L + + R ++ ++
Sbjct: 421 SKRIMAL-EKLEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRIKELEAIES 477
Query: 696 ELMTTRIREVEALTELKELRL-----------KVMELETQVQVSTNQLRRQDEEARLLRE 744
L T E LT+LK L + K+ + E ++Q +++QL+ + + + E
Sbjct: 478 RLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTE 537
Query: 745 NL----DAALQRERALQTRQREFQHKYADLESKAKYESMQAN---IRNMEDAQRIAELET 797
L AL+ + ++ + + DL++K K E + N R R+ LE
Sbjct: 538 KLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEA 597
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
++ LKN++ G+ ++++++EL ++V LK ++ ++A
Sbjct: 598 IEKDF-LKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKA 644
>AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protein
130b protein.
Length = 1133
Score = 50.4 bits (115), Expect = 3e-05
Identities = 89/468 (19%), Positives = 193/468 (41%), Gaps = 42/468 (8%)
Query: 402 LLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI 461
LL + E + K I +E+ + E +Q K++ L++E T +K+ +
Sbjct: 195 LLEQECERLKKLIDQEIKSQEEKEQE-----------KEKRVTTLKEELTKLKSFALMVV 243
Query: 462 AVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA-LRRAN 520
+ L + L +Q++ + E E++ L++E+Q + +
Sbjct: 244 DEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFH 303
Query: 521 VDMQQRLAVALDEI---RSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
D +A +E R L+ +A + + LE T + + EEL +
Sbjct: 304 QDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+D +E +++ L + ++ L L L+ + L ++ L
Sbjct: 364 GNAGIMAEVEELRKRVLD-MEGKDEELIK--MEEQCRDLNKRLERETLQSKDFKLEVEKL 420
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK--KLLRAWEGRSADMLKLDE 695
+R+ L E + + KQE + ++ N+ + M T + + L + + R ++ ++
Sbjct: 421 SKRIMAL-EKLEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRIKELEAIES 477
Query: 696 ELMTTRIREVEALTELKELRL-----------KVMELETQVQVSTNQLRRQDEEARLLRE 744
L T E LT+LK L + K+ + E ++Q +++QL+ + + + E
Sbjct: 478 RLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTE 537
Query: 745 NL----DAALQRERALQTRQREFQHKYADLESKAKYESMQAN---IRNMEDAQRIAELET 797
L AL+ + ++ + + DL++K K E + N R R+ LE
Sbjct: 538 KLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEA 597
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
++ LKN++ G+ ++++++EL ++V LK ++ ++A
Sbjct: 598 IEKDF-LKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKA 644
>AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protein
130a protein.
Length = 1135
Score = 50.4 bits (115), Expect = 3e-05
Identities = 89/468 (19%), Positives = 193/468 (41%), Gaps = 42/468 (8%)
Query: 402 LLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI 461
LL + E + K I +E+ + E +Q K++ L++E T +K+ +
Sbjct: 195 LLEQECERLKKLIDQEIKSQEEKEQE-----------KEKRVTTLKEELTKLKSFALMVV 243
Query: 462 AVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA-LRRAN 520
+ L + L +Q++ + E E++ L++E+Q + +
Sbjct: 244 DEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFH 303
Query: 521 VDMQQRLAVALDEI---RSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
D +A +E R L+ +A + + LE T + + EEL +
Sbjct: 304 QDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+D +E +++ L + ++ L L L+ + L ++ L
Sbjct: 364 GNAGIMAEVEELRKRVLD-MEGKDEELIK--MEEQCRDLNKRLERETLQSKDFKLEVEKL 420
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK--KLLRAWEGRSADMLKLDE 695
+R+ L E + + KQE + ++ N+ + M T + + L + + R ++ ++
Sbjct: 421 SKRIMAL-EKLEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRIKELEAIES 477
Query: 696 ELMTTRIREVEALTELKELRL-----------KVMELETQVQVSTNQLRRQDEEARLLRE 744
L T E LT+LK L + K+ + E ++Q +++QL+ + + + E
Sbjct: 478 RLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTE 537
Query: 745 NL----DAALQRERALQTRQREFQHKYADLESKAKYESMQAN---IRNMEDAQRIAELET 797
L AL+ + ++ + + DL++K K E + N R R+ LE
Sbjct: 538 KLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEA 597
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
++ LKN++ G+ ++++++EL ++V LK ++ ++A
Sbjct: 598 IEKDF-LKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKA 644
>AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protein
90 protein.
Length = 764
Score = 50.4 bits (115), Expect = 3e-05
Identities = 89/468 (19%), Positives = 193/468 (41%), Gaps = 42/468 (8%)
Query: 402 LLSLDMESILKYIQKELPLKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI 461
LL + E + K I +E+ + E +Q K++ L++E T +K+ +
Sbjct: 195 LLEQECERLKKLIDQEIKSQEEKEQE-----------KEKRVTTLKEELTKLKSFALMVV 243
Query: 462 AVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQA-LRRAN 520
+ L + L +Q++ + E E++ L++E+Q + +
Sbjct: 244 DEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFH 303
Query: 521 VDMQQRLAVALDEI---RSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
D +A +E R L+ +A + + LE T + + EEL +
Sbjct: 304 QDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+D +E +++ L + ++ L L L+ + L ++ L
Sbjct: 364 GNAGIMAEVEELRKRVLD-MEGKDEELIK--MEEQCRDLNKRLERETLQSKDFKLEVEKL 420
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPK--KLLRAWEGRSADMLKLDE 695
+R+ L E + + KQE + ++ N+ + M T + + L + + R ++ ++
Sbjct: 421 SKRIMAL-EKLEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRIKELEAIES 477
Query: 696 ELMTTRIREVEALTELKELRL-----------KVMELETQVQVSTNQLRRQDEEARLLRE 744
L T E LT+LK L + K+ + E ++Q +++QL+ + + + E
Sbjct: 478 RLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTE 537
Query: 745 NL----DAALQRERALQTRQREFQHKYADLESKAKYESMQAN---IRNMEDAQRIAELET 797
L AL+ + ++ + + DL++K K E + N R R+ LE
Sbjct: 538 KLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEA 597
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
++ LKN++ G+ ++++++EL ++V LK ++ ++A
Sbjct: 598 IEKDF-LKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKA 644
>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
Length = 2479
Score = 50.0 bits (114), Expect = 4e-05
Identities = 54/269 (20%), Positives = 124/269 (46%), Gaps = 23/269 (8%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
D L+ +N ++R +N+ HL+ E I++K + N L+ ++++ + ++W++ +
Sbjct: 978 DILQKDNMLVQRT---SNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKL 1034
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV-EAL-TELK 712
+ + +S SDI++ KK+ +M +L+E +++ E L T LK
Sbjct: 1035 GNESSMDKAKKSITNSDIVSISKKI------TMLEMKELNERQRAEHCQKMYEHLRTSLK 1088
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENL---------DAALQRERALQTRQREF 763
++ + ELET+ T + ++LR+ L DA QR L+ + E
Sbjct: 1089 QMEERNFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMEL 1148
Query: 764 QHKYADLESKAKYESMQANIRNMEDAQRIAELET---EVSEYKLKNEVMATEGELRNNNM 820
+ + + L + Q I N + R E+E+ ++ +Y+ +++ + +L +N+
Sbjct: 1149 KVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNV 1208
Query: 821 DDSDRVRELQEQVAELKAEIMRLEAWKSR 849
++ + +++ ++EA+ R
Sbjct: 1209 SLQLSEATALGKLESITSKLQKMEAYNLR 1237
Score = 41.5 bits (93), Expect = 0.013
Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 690 MLKLDEELMTTRIREVEALTELK-----ELRLKVMELETQVQVSTNQLRRQDEEARLLRE 744
++K+ + + + EVE E + +L+ KVM+LE +++++ +D R LR
Sbjct: 58 LMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRD--TRFLRN 115
Query: 745 NLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKL 804
+ Q E+ L+ + RE + +LE + K A +RN E ++L E K
Sbjct: 116 EI---CQLEKQLEQKDRELEDMEKELEKEKKVNEQLA-LRNEEAENENSKLRRENKRLKK 171
Query: 805 KNEVMATE 812
KNE + +
Sbjct: 172 KNEQLCQD 179
Score = 41.5 bits (93), Expect = 0.013
Identities = 99/459 (21%), Positives = 184/459 (40%), Gaps = 42/459 (9%)
Query: 406 DMESILKYIQKELP-LKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI--A 462
D++ +L QKE LK+E N +++L K +K K+Q + A
Sbjct: 1689 DLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERL-KSQLALKEKQQKALSRA 1747
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFA--LDREVQALRRAN 520
+L + ++R+ V+ VDR E +T L+ + L+ A
Sbjct: 1748 LLELRAEMTAAAEERIISATSQKEAHLN--VQQIVDRHTRELKTQVEDLNENLLKLKEAL 1805
Query: 521 VDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXX 580
+ R D + L + + + + + Q+++EL R ++
Sbjct: 1806 KTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKP 1865
Query: 581 XXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQR 640
I+EL+ + K L Q ++ V + +L +K + A+ L + ++
Sbjct: 1866 LTDNKQSL-----IEELQRKVKKLENQ-LEGKVEEV--DLKPMKEKNAKEELIRWEEGKK 1917
Query: 641 VSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA-TPKKLLRAWEGRSADMLKLDEELMT 699
E + L+E + E Q N + D+ A K+ L + +D+ L
Sbjct: 1918 WQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTTGMTVDQVL-- 1975
Query: 700 TRIREVEALTELKELRLKVMELETQV-QVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
IR +E+ EL+EL+ + ++LE + + +Q +D D LQ R LQ
Sbjct: 1976 -GIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVE------DLHLQ-NRYLQE 2027
Query: 759 RQREFQHKYA-DLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRN 817
+ + +++ D SK ++++ + QR EL+ E KL +E + + +L
Sbjct: 2028 KLHALEKQFSKDTYSKPSISGIESD----DHCQREQELQKE--NLKLSSENIELKFQLEQ 2081
Query: 818 NNMD---DSDRVRELQEQVAELKAEIMRLEAWKSRALGH 853
N D ++VR+L+E LK E +A R LGH
Sbjct: 2082 ANKDLPRLKNQVRDLKEMCEFLKKE----KAEVQRKLGH 2116
Score = 37.1 bits (82), Expect = 0.28
Identities = 45/188 (23%), Positives = 85/188 (45%), Gaps = 19/188 (10%)
Query: 686 RSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDE----EARL 741
R++++ L+ E ++ + +VE++ KEL + +L T Q + + +E +A+
Sbjct: 989 RTSNLEHLECENISLK-EQVESIN--KELEITKEKLHTIEQAWEQETKLGNESSMDKAKK 1045
Query: 742 LRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSE 801
N D ++ +E + + YE ++ +++ ME+ R ELET+ +E
Sbjct: 1046 SITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEE--RNFELETKFAE 1103
Query: 802 Y-KLKNEVMATEGELRNNNMD-------DSDRVR--ELQEQVAELKAEIMRLEAWKSRAL 851
K+ + E LR+ D D+DR R EL++ ELK E+ +L A
Sbjct: 1104 LTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEVSKLREISDIAR 1163
Query: 852 GHTELSRA 859
E+ A
Sbjct: 1164 RQVEILNA 1171
Score = 35.9 bits (79), Expect = 0.64
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 16/185 (8%)
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
A+ N S+ DL+Q V E +E Q+ + ++ ++ V + T + L R +
Sbjct: 2287 AKKNQSITDLKQLVKEATEREQK-VNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLR 2345
Query: 688 ADMLKLDEELMTTRIREVEA----------LTELKELRLKVMELETQVQVSTNQLRRQDE 737
+LD+E I ++EA + + +L+ K+ +LETQ+++S + + E
Sbjct: 2346 LANHQLDKE-KAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQHLKE 2404
Query: 738 EARLLR---ENLDAALQRE-RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
E + L+ EN D + E L+ +E K LE K K S Q +
Sbjct: 2405 EIKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQLGVELTSPVAASE 2464
Query: 794 ELETE 798
E E E
Sbjct: 2465 EFEDE 2469
Score = 35.5 bits (78), Expect = 0.84
Identities = 33/157 (21%), Positives = 71/157 (45%), Gaps = 10/157 (6%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+ E +++N+ L R+ ++ + + K + LK+L + +L E + LQ
Sbjct: 602 MSEAQSKNEFLSRELIEKERDLERSRTVIAKFQN-----KLKELVEENKQLEEGMKEILQ 656
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSAD-----MLKLDEELMTTRIREVEAL 708
K+ V+ S I+ + ++L+ A E ++A+ L L ++ R E
Sbjct: 657 AIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELR 716
Query: 709 TELKELRLKVMELETQVQVSTNQLRRQDEEARLLREN 745
EL+E R + + Q+ + ++ ++E LLR++
Sbjct: 717 QELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQS 753
Score = 35.5 bits (78), Expect = 0.84
Identities = 62/343 (18%), Positives = 137/343 (39%), Gaps = 20/343 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKH 562
EE F L+ + L + N+D Q+ + DE+ + RQ LE E +
Sbjct: 1091 EERNFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILE-LEKNEMELK 1149
Query: 563 EELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN-VAHLQDELI 621
E+++ L+ ++ L + + Q + + +A L +
Sbjct: 1150 VEVSK-LREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNV 1208
Query: 622 AVKLREAEANLSLKDLRQRVSELSE---SWQRHLQEHKQEAPAAPVQS-NVVSDIMATPK 677
+++L EA A L+ + ++ ++ ++ L E +Q A ++ N + T +
Sbjct: 1209 SLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQ 1268
Query: 678 KLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDE 737
L R + G A L E+ T I +L+ +LK+M+ Q + +
Sbjct: 1269 SLRRQFSG--ALPLAQQEKFSKTMI-------QLQNDKLKIMQEMKNSQQEHRNMENKTL 1319
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELET 797
E L + L+ + + + Q+ + + +E + + + ++ N ++D + I L
Sbjct: 1320 EMELKLKGLEELISTLKDTKGAQKVI-NWHMKIE-ELRLQELKLNRELVKDKEEIKYLNN 1377
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
+SEY + + + E E+ N +R ++ +L+ ++
Sbjct: 1378 IISEY--ERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQL 1418
Score = 33.9 bits (74), Expect = 2.6
Identities = 49/243 (20%), Positives = 97/243 (39%), Gaps = 9/243 (3%)
Query: 595 DELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHL 652
+E ENEN LRR+ R+ L ++I + + +L R S+ +
Sbjct: 153 EEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKN 212
Query: 653 QEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
E Q + I +++ + E +M K+ +E + + +
Sbjct: 213 YELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVID 272
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR----EFQHKYA 768
+L+ + + QVQ T+ L+ ++EE + ++A ++ + + + + E+Q
Sbjct: 273 QLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLH 332
Query: 769 DLESKAKYESMQANIRN-MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR 827
+L K K + A+ N M Q I E ++++ L +V E+ N D
Sbjct: 333 NLREKLKNAQLDADKSNVMALQQGIQERDSQIK--MLTEQVEQYTKEMEKNTCIIEDLKN 390
Query: 828 ELQ 830
ELQ
Sbjct: 391 ELQ 393
Score = 32.7 bits (71), Expect = 5.9
Identities = 42/183 (22%), Positives = 86/183 (46%), Gaps = 17/183 (9%)
Query: 695 EELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDA--ALQR 752
+EL T ++ +++T+LK+L + E E +V L +Q + + + E + L+R
Sbjct: 2280 KELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKR 2339
Query: 753 E-RALQTRQREFQHKYADL----ESKAKYESMQANIRNMED-AQRIAELET-----EVSE 801
E + L+ + + A+L E+ ++ I + + ++I +LET ++ +
Sbjct: 2340 ELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEK 2399
Query: 802 YKLKNEVMATEGELRNNNMDDSDRVRELQ-EQVAELKAEIMRLEAWK--SRALGHTELSR 858
LK E+ + EL N + + + +L+ E+K I+ E K S LG EL+
Sbjct: 2400 QHLKEEIKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQLG-VELTS 2458
Query: 859 AIS 861
++
Sbjct: 2459 PVA 2461
>AL137265-1|CAB70664.1| 992|Homo sapiens hypothetical protein
protein.
Length = 992
Score = 50.0 bits (114), Expect = 4e-05
Identities = 61/239 (25%), Positives = 111/239 (46%), Gaps = 18/239 (7%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E + +LK + + V+++ E QRHL E KQE +Q +++LR + +
Sbjct: 359 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQE----KMQQLREKLCQEEEEEILRLHQQK 414
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRLKVM--ELETQVQVSTNQLRRQDEEA-RLLR 743
+ L E L E + E + RL + ++++ Q +Q+R + E + + LR
Sbjct: 415 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR 474
Query: 744 ENLDAALQRERA-LQTRQRE-FQHKYADLESKAKYESMQANIRNMEDAQRIAE-LETEVS 800
E L++ + ERA L+ + R+ + ++E+ K E N + Q++ E LE E
Sbjct: 475 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 534
Query: 801 E--YKLKNEVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLEAWKSRALGHTE 855
E L+ E A E E ++++ R V LQ+++ E + + EA + LG E
Sbjct: 535 EAVATLEKEHSA-ELERLCSSLEAKHREVVSSLQKKIQEAQ---QKEEAQLQKCLGQVE 589
Score = 36.7 bits (81), Expect = 0.36
Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 9/204 (4%)
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE 713
E + P AP + + + A + + + E +L+ +E M ++RE E +E
Sbjct: 348 EVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKM-QQLREKLCQEEEEE 406
Query: 714 LRLKVMELETQVQVSTNQLRR--QDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
+ + E + +L++ ++EEAR +RE L RA + E
Sbjct: 407 ILRLHQQKEQSLSSLRERLQKAIEEEEAR-MREEESQRLSWLRAQVQSSTQADEDQIRAE 465
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEY--KLKNEVMATE-GELRNNNMDDSDRVRE 828
+A + ++ + + + A+R A LE + + +LK E+ A+E E N +++
Sbjct: 466 QEASLQKLREELESQQKAER-ASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQ 524
Query: 829 LQEQV-AELKAEIMRLEAWKSRAL 851
L+EQ+ E K + LE S L
Sbjct: 525 LREQLEGERKEAVATLEKEHSAEL 548
Score = 36.7 bits (81), Expect = 0.36
Identities = 39/177 (22%), Positives = 79/177 (44%), Gaps = 12/177 (6%)
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
+ +A E A+ K EL+ E+E L E L+ + E ++ + R +++E
Sbjct: 636 MAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQE 695
Query: 739 ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETE 798
+L LD L+TR ++ + + A LE + E+ + + + D QR L++E
Sbjct: 696 RKLQDLELD--------LETRAKDVKARLALLE--VQEETARREKQQLLDVQRQVALKSE 745
Query: 799 --VSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGH 853
+ ++ E L +N + + ELQ + +L++++ L+A + H
Sbjct: 746 EATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKH 802
>AK125995-1|BAC86384.1| 842|Homo sapiens protein ( Homo sapiens
cDNA FLJ44007 fis, clone TESTI4023762. ).
Length = 842
Score = 50.0 bits (114), Expect = 4e-05
Identities = 61/239 (25%), Positives = 111/239 (46%), Gaps = 18/239 (7%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E + +LK + + V+++ E QRHL E KQE +Q +++LR + +
Sbjct: 467 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQE----KMQQLREKLCQEEEEEILRLHQQK 522
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRLKVM--ELETQVQVSTNQLRRQDEEA-RLLR 743
+ L E L E + E + RL + ++++ Q +Q+R + E + + LR
Sbjct: 523 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR 582
Query: 744 ENLDAALQRERA-LQTRQRE-FQHKYADLESKAKYESMQANIRNMEDAQRIAE-LETEVS 800
E L++ + ERA L+ + R+ + ++E+ K E N + Q++ E LE E
Sbjct: 583 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 642
Query: 801 E--YKLKNEVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLEAWKSRALGHTE 855
E L+ E A E E ++++ R V LQ+++ E + + EA + LG E
Sbjct: 643 EAVATLEKEHSA-ELERLCSSLEAKHREVVSSLQKKIQEAQ---QKEEAQLQKCLGQVE 697
Score = 39.5 bits (88), Expect = 0.052
Identities = 53/216 (24%), Positives = 94/216 (43%), Gaps = 10/216 (4%)
Query: 642 SELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTR 701
S S S Q LQ E P AP + + + A + + + E +L+ +E M +
Sbjct: 445 SAASLSLQLSLQRRSTE-PVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKM-QQ 502
Query: 702 IREVEALTELKELRLKVMELETQVQVSTNQLRR--QDEEARLLRENLDAALQRERALQTR 759
+RE E +E+ + E + +L++ ++EEAR +RE L RA
Sbjct: 503 LREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEAR-MREEESQRLSWLRAQVQS 561
Query: 760 QREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY--KLKNEVMATE-GELR 816
+ E +A + ++ + + + A+R A LE + + +LK E+ A+E E
Sbjct: 562 STQADEDQIRAEQEASLQKLREELESQQKAER-ASLEQKNRQMLEQLKEEIEASEKSEQA 620
Query: 817 NNNMDDSDRVRELQEQV-AELKAEIMRLEAWKSRAL 851
N +++L+EQ+ E K + LE S L
Sbjct: 621 ALNAAKEKALQQLREQLEGERKEAVATLEKEHSAEL 656
>AB028975-1|BAA83004.2| 1456|Homo sapiens KIAA1052 protein protein.
Length = 1456
Score = 50.0 bits (114), Expect = 4e-05
Identities = 61/239 (25%), Positives = 111/239 (46%), Gaps = 18/239 (7%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E + +LK + + V+++ E QRHL E KQE +Q +++LR + +
Sbjct: 589 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQE----KMQQLREKLCQEEEEEILRLHQQK 644
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRLKVM--ELETQVQVSTNQLRRQDEEA-RLLR 743
+ L E L E + E + RL + ++++ Q +Q+R + E + + LR
Sbjct: 645 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR 704
Query: 744 ENLDAALQRERA-LQTRQRE-FQHKYADLESKAKYESMQANIRNMEDAQRIAE-LETEVS 800
E L++ + ERA L+ + R+ + ++E+ K E N + Q++ E LE E
Sbjct: 705 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 764
Query: 801 E--YKLKNEVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLEAWKSRALGHTE 855
E L+ E A E E ++++ R V LQ+++ E + + EA + LG E
Sbjct: 765 EAVATLEKEHSA-ELERLCSSLEAKHREVVSSLQKKIQEAQ---QKEEAQLQKCLGQVE 819
Score = 36.7 bits (81), Expect = 0.36
Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 9/204 (4%)
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE 713
E + P AP + + + A + + + E +L+ +E M ++RE E +E
Sbjct: 578 EVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKM-QQLREKLCQEEEEE 636
Query: 714 LRLKVMELETQVQVSTNQLRR--QDEEARLLRENLDAALQRERALQTRQREFQHKYADLE 771
+ + E + +L++ ++EEAR +RE L RA + E
Sbjct: 637 ILRLHQQKEQSLSSLRERLQKAIEEEEAR-MREEESQRLSWLRAQVQSSTQADEDQIRAE 695
Query: 772 SKAKYESMQANIRNMEDAQRIAELETEVSEY--KLKNEVMATE-GELRNNNMDDSDRVRE 828
+A + ++ + + + A+R A LE + + +LK E+ A+E E N +++
Sbjct: 696 QEASLQKLREELESQQKAER-ASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQ 754
Query: 829 LQEQV-AELKAEIMRLEAWKSRAL 851
L+EQ+ E K + LE S L
Sbjct: 755 LREQLEGERKEAVATLEKEHSAEL 778
Score = 36.7 bits (81), Expect = 0.36
Identities = 39/177 (22%), Positives = 79/177 (44%), Gaps = 12/177 (6%)
Query: 679 LLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
+ +A E A+ K EL+ E+E L E L+ + E ++ + R +++E
Sbjct: 866 MAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQE 925
Query: 739 ARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETE 798
+L LD L+TR ++ + + A LE + E+ + + + D QR L++E
Sbjct: 926 RKLQDLELD--------LETRAKDVKARLALLE--VQEETARREKQQLLDVQRQVALKSE 975
Query: 799 --VSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGH 853
+ ++ E L +N + + ELQ + +L++++ L+A + H
Sbjct: 976 EATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKH 1032
>AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.
Length = 1540
Score = 50.0 bits (114), Expect = 4e-05
Identities = 54/269 (20%), Positives = 124/269 (46%), Gaps = 23/269 (8%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
D L+ +N ++R +N+ HL+ E I++K + N L+ ++++ + ++W++ +
Sbjct: 39 DILQKDNMLVQRT---SNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKL 95
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV-EAL-TELK 712
+ + +S SDI++ KK+ +M +L+E +++ E L T LK
Sbjct: 96 GNESSMDKAKKSITNSDIVSISKKI------TMLEMKELNERQRAEHCQKMYEHLRTSLK 149
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENL---------DAALQRERALQTRQREF 763
++ + ELET+ T + ++LR+ L DA QR L+ + E
Sbjct: 150 QMEERNFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMEL 209
Query: 764 QHKYADLESKAKYESMQANIRNMEDAQRIAELET---EVSEYKLKNEVMATEGELRNNNM 820
+ + + L + Q I N + R E+E+ ++ +Y+ +++ + +L +N+
Sbjct: 210 KVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNV 269
Query: 821 DDSDRVRELQEQVAELKAEIMRLEAWKSR 849
++ + +++ ++EA+ R
Sbjct: 270 SLQLSEATALGKLESITSKLQKMEAYNLR 298
Score = 41.5 bits (93), Expect = 0.013
Identities = 99/459 (21%), Positives = 184/459 (40%), Gaps = 42/459 (9%)
Query: 406 DMESILKYIQKELP-LKAEADQAAFMNLAYSVKVNPKKMKKLEKEYTVIKTKEQGDI--A 462
D++ +L QKE LK+E N +++L K +K K+Q + A
Sbjct: 750 DLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERL-KSQLALKEKQQKALSRA 808
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFA--LDREVQALRRAN 520
+L + ++R+ V+ VDR E +T L+ + L+ A
Sbjct: 809 LLELRAEMTAAAEERIISATSQKEAHLN--VQQIVDRHTRELKTQVEDLNENLLKLKEAL 866
Query: 521 VDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXXXXX 580
+ R D + L + + + + + Q+++EL R ++
Sbjct: 867 KTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKP 926
Query: 581 XXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQR 640
I+EL+ + K L Q ++ V + +L +K + A+ L + ++
Sbjct: 927 LTDNKQSL-----IEELQRKVKKLENQ-LEGKVEEV--DLKPMKEKNAKEELIRWEEGKK 978
Query: 641 VSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA-TPKKLLRAWEGRSADMLKLDEELMT 699
E + L+E + E Q N + D+ A K+ L + +D+ L
Sbjct: 979 WQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTTGMTVDQVL-- 1036
Query: 700 TRIREVEALTELKELRLKVMELETQV-QVSTNQLRRQDEEARLLRENLDAALQRERALQT 758
IR +E+ EL+EL+ + ++LE + + +Q +D D LQ R LQ
Sbjct: 1037 -GIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVE------DLHLQ-NRYLQE 1088
Query: 759 RQREFQHKYA-DLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRN 817
+ + +++ D SK ++++ + QR EL+ E KL +E + + +L
Sbjct: 1089 KLHALEKQFSKDTYSKPSISGIESD----DHCQREQELQKE--NLKLSSENIELKFQLEQ 1142
Query: 818 NNMD---DSDRVRELQEQVAELKAEIMRLEAWKSRALGH 853
N D ++VR+L+E LK E +A R LGH
Sbjct: 1143 ANKDLPRLKNQVRDLKEMCEFLKKE----KAEVQRKLGH 1177
Score = 37.1 bits (82), Expect = 0.28
Identities = 45/188 (23%), Positives = 85/188 (45%), Gaps = 19/188 (10%)
Query: 686 RSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDE----EARL 741
R++++ L+ E ++ + +VE++ KEL + +L T Q + + +E +A+
Sbjct: 50 RTSNLEHLECENISLK-EQVESIN--KELEITKEKLHTIEQAWEQETKLGNESSMDKAKK 106
Query: 742 LRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSE 801
N D ++ +E + + YE ++ +++ ME+ R ELET+ +E
Sbjct: 107 SITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEE--RNFELETKFAE 164
Query: 802 Y-KLKNEVMATEGELRNNNMD-------DSDRVR--ELQEQVAELKAEIMRLEAWKSRAL 851
K+ + E LR+ D D+DR R EL++ ELK E+ +L A
Sbjct: 165 LTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEVSKLREISDIAR 224
Query: 852 GHTELSRA 859
E+ A
Sbjct: 225 RQVEILNA 232
Score = 35.9 bits (79), Expect = 0.64
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 16/185 (8%)
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
A+ N S+ DL+Q V E +E Q+ + ++ ++ V + T + L R +
Sbjct: 1348 AKKNQSITDLKQLVKEATEREQK-VNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLR 1406
Query: 688 ADMLKLDEELMTTRIREVEA----------LTELKELRLKVMELETQVQVSTNQLRRQDE 737
+LD+E I ++EA + + +L+ K+ +LETQ+++S + + E
Sbjct: 1407 LANHQLDKE-KAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQHLKE 1465
Query: 738 EARLLR---ENLDAALQRE-RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
E + L+ EN D + E L+ +E K LE K K S Q +
Sbjct: 1466 EIKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQLGVELTSPVAASE 1525
Query: 794 ELETE 798
E E E
Sbjct: 1526 EFEDE 1530
Score = 35.5 bits (78), Expect = 0.84
Identities = 62/343 (18%), Positives = 137/343 (39%), Gaps = 20/343 (5%)
Query: 503 EEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKH 562
EE F L+ + L + N+D Q+ + DE+ + RQ LE E +
Sbjct: 152 EERNFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILE-LEKNEMELK 210
Query: 563 EELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN-VAHLQDELI 621
E+++ L+ ++ L + + Q + + +A L +
Sbjct: 211 VEVSK-LREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNV 269
Query: 622 AVKLREAEANLSLKDLRQRVSELSE---SWQRHLQEHKQEAPAAPVQS-NVVSDIMATPK 677
+++L EA A L+ + ++ ++ ++ L E +Q A ++ N + T +
Sbjct: 270 SLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQ 329
Query: 678 KLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDE 737
L R + G A L E+ T I +L+ +LK+M+ Q + +
Sbjct: 330 SLRRQFSG--ALPLAQQEKFSKTMI-------QLQNDKLKIMQEMKNSQQEHRNMENKTL 380
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELET 797
E L + L+ + + + Q+ + + +E + + + ++ N ++D + I L
Sbjct: 381 EMELKLKGLEELISTLKDTKGAQKVI-NWHMKIE-ELRLQELKLNRELVKDKEEIKYLNN 438
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
+SEY + + + E E+ N +R ++ +L+ ++
Sbjct: 439 IISEY--ERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQL 479
Score = 32.7 bits (71), Expect = 5.9
Identities = 42/183 (22%), Positives = 86/183 (46%), Gaps = 17/183 (9%)
Query: 695 EELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDA--ALQR 752
+EL T ++ +++T+LK+L + E E +V L +Q + + + E + L+R
Sbjct: 1341 KELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKR 1400
Query: 753 E-RALQTRQREFQHKYADL----ESKAKYESMQANIRNMED-AQRIAELET-----EVSE 801
E + L+ + + A+L E+ ++ I + + ++I +LET ++ +
Sbjct: 1401 ELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEK 1460
Query: 802 YKLKNEVMATEGELRNNNMDDSDRVRELQ-EQVAELKAEIMRLEAWK--SRALGHTELSR 858
LK E+ + EL N + + + +L+ E+K I+ E K S LG EL+
Sbjct: 1461 QHLKEEIKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQLG-VELTS 1519
Query: 859 AIS 861
++
Sbjct: 1520 PVA 1522
>L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein.
Length = 579
Score = 49.6 bits (113), Expect = 5e-05
Identities = 78/342 (22%), Positives = 139/342 (40%), Gaps = 27/342 (7%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC 568
LD E++ LR+ + + A E+ L +A+ + LEG ++ ++ +E+
Sbjct: 107 LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETH 166
Query: 569 LQXXXXXXXXXXXXXXXXXXXXXXXIDELENE-NKSLRRQRVDNNVAHLQDELIAVKLRE 627
LQ I+EL+ E K++ Q+ + L +L + +
Sbjct: 167 LQSLQFDKEQMVAVTEANEALKKQ-IEELQQEARKAITEQK--QKMRRLGSDLTSA---Q 220
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
E K V LS Q L K+ A A Q + L +
Sbjct: 221 KEMKTKHKAYENAVGILSRRLQEALAA-KEAADAELGQLRAQGGSSDSSLALHERIQALE 279
Query: 688 ADMLKLDEE--LMTTRIREVEALT--ELKELRLKVMELETQVQVS---TNQLRRQDEEAR 740
A++ + L+ ++EV ALT EL+E R KV+ELE ++Q S +++R +E +
Sbjct: 280 AELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNK 339
Query: 741 LLRENLDAALQRERALQTRQREFQHKYADLE---SKAKYESMQANIRNMEDAQRIAELET 797
L L+ + L + + LE +K + + +Q N++ QR
Sbjct: 340 KLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQR-----K 394
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E + ++K+ V A + L + ++V L+EQVA K E
Sbjct: 395 EEEDRQMKHLVQALQASLEK----EKEKVNSLKEQVAAAKVE 432
Score = 42.7 bits (96), Expect = 0.006
Identities = 53/244 (21%), Positives = 112/244 (45%), Gaps = 20/244 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSA 688
E + +L+ LR+ ++ + HLQ QE A Q + + K ++ A+ +
Sbjct: 36 ETSETLEKLREELA-IKSGQVEHLQ---QETAALKKQMQKIKEQFLQQKVMVEAYRRDAT 91
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD- 747
+L EL TR R +ELKELR ++M++ + + + +L R E +R+++
Sbjct: 92 SKDQLISELKATRKR---LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMAD 148
Query: 748 -----AALQRER-ALQTRQREFQHKYADLESKAK-YESMQANIRNMEDAQRIAELETEVS 800
+ Q+ER ++T + Q + + + E+++ I ++ R A E +
Sbjct: 149 LEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQK 208
Query: 801 EYKLKNEVMATEGELRNNNMDDSDRV----RELQEQVAELKAEIMRLEAWKSRALGHTEL 856
+L +++ + + E++ + + V R LQE +A +A L +++ G ++
Sbjct: 209 MRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQG-GSSDS 267
Query: 857 SRAI 860
S A+
Sbjct: 268 SLAL 271
Score = 36.3 bits (80), Expect = 0.48
Identities = 43/204 (21%), Positives = 95/204 (46%), Gaps = 22/204 (10%)
Query: 612 NVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSN---- 667
++ L ++ AV R+ E + +K L Q + E + + K++ AA V++
Sbjct: 379 DLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRR 438
Query: 668 ---VVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQ 724
S ++ KK L+A E + KL E +IRE + E+ + + ++ E Q
Sbjct: 439 HFKAASLELSEVKKELQAKEHL---VQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQ 495
Query: 725 VQVSTNQLRRQ-------DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYE 777
+Q+ QL Q ++E L+ +D Q+ER +Q+ +++ + + + + E
Sbjct: 496 LQLLQKQLDEQLSKQPVGNQEMENLKWEVD---QKEREIQSLKQQLD--LTEQQGRKELE 550
Query: 778 SMQANIRNMEDAQRIAELETEVSE 801
+Q ++N++ +A+ + +++
Sbjct: 551 GLQQLLQNVKSELEMAQEDLSMTQ 574
>D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein.
Length = 1530
Score = 49.6 bits (113), Expect = 5e-05
Identities = 78/342 (22%), Positives = 139/342 (40%), Gaps = 27/342 (7%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC 568
LD E++ LR+ + + A E+ L +A+ + LEG ++ ++ +E+
Sbjct: 876 LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETH 935
Query: 569 LQXXXXXXXXXXXXXXXXXXXXXXXIDELENE-NKSLRRQRVDNNVAHLQDELIAVKLRE 627
LQ I+EL+ E K++ Q+ + L +L + +
Sbjct: 936 LQSLQFDKEQMVAVTEANEALKKQ-IEELQQEARKAITEQK--QKMRRLGSDLTSA---Q 989
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
E K V LS Q L K+ A A Q + L +
Sbjct: 990 KEMKTKHKAYENAVGILSRRLQEALAA-KEAADAELGQLRAQGGSSDSSLALHERIQALE 1048
Query: 688 ADMLKLDEE--LMTTRIREVEALT--ELKELRLKVMELETQVQVS---TNQLRRQDEEAR 740
A++ + L+ ++EV ALT EL+E R KV+ELE ++Q S +++R +E +
Sbjct: 1049 AELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNK 1108
Query: 741 LLRENLDAALQRERALQTRQREFQHKYADLE---SKAKYESMQANIRNMEDAQRIAELET 797
L L+ + L + + LE +K + + +Q N++ QR
Sbjct: 1109 KLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQR-----K 1163
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E + ++K+ V A + L + ++V L+EQVA K E
Sbjct: 1164 EEEDRQMKHLVQALQASLEK----EKEKVNSLKEQVAAAKVE 1201
Score = 45.2 bits (102), Expect = 0.001
Identities = 79/379 (20%), Positives = 152/379 (40%), Gaps = 25/379 (6%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
+++ EGE E L R + ++Q L + LE E+ L T+
Sbjct: 673 RLEEFEGERER--LQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQ 730
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
A Q E+ LQ I L+NE L
Sbjct: 731 EAL-QSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGK 789
Query: 616 LQDELIAVKLREA--EANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
+ + A +L E E + +L+ LR+ ++ + HLQ QE A Q + +
Sbjct: 790 EELDRGARRLEEGTEETSETLEKLREELA-IKSGQVEHLQ---QETAALKKQMQKIKEQF 845
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
K ++ A+ + +L EL TR R +ELKELR ++M++ + + + +L
Sbjct: 846 LQQKVMVEAYRRDATSKDQLISELKATRKR---LDSELKELRQELMQVHGEKRTAEAELS 902
Query: 734 RQDEEARLLRENLD------AALQRER-ALQTRQREFQHKYADLESKAK-YESMQANIRN 785
R E +R+++ + Q+ER ++T + Q + + + E+++ I
Sbjct: 903 RLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEE 962
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRV----RELQEQVAELKAEIM 841
++ R A E + +L +++ + + E++ + + V R LQE +A +A
Sbjct: 963 LQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADA 1022
Query: 842 RLEAWKSRALGHTELSRAI 860
L +++ G ++ S A+
Sbjct: 1023 ELGQLRAQG-GSSDSSLAL 1040
Score = 43.2 bits (97), Expect = 0.004
Identities = 55/245 (22%), Positives = 115/245 (46%), Gaps = 30/245 (12%)
Query: 612 NVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSN---- 667
++ L ++ AV R+ E + +K L Q + E + + K++ AA V++
Sbjct: 1148 DLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRR 1207
Query: 668 ---VVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQ 724
S ++ KK L+A E + KL E +IRE + E+ + + ++ E Q
Sbjct: 1208 HFKAASLELSEVKKELQAKEHL---VQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQ 1264
Query: 725 VQVSTNQLRRQ-------DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYE 777
+Q+ QL Q ++E L+ +D Q+ER +Q+ +++ + + + + E
Sbjct: 1265 LQLLQKQLDEQLSKQPVGNQEMENLKWEVD---QKEREIQSLKQQLD--LTEQQGRKELE 1319
Query: 778 SMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELK 837
+Q ++N++ +A+ + +++ K K + A EL+NN ++ L +Q +LK
Sbjct: 1320 GLQQLLQNVKSELEMAQEDLSMTQ-KDKFMLQAKVSELKNN-------MKTLLQQNQQLK 1371
Query: 838 AEIMR 842
++ R
Sbjct: 1372 LDLRR 1376
>BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for
IMAGE:4139784) protein.
Length = 663
Score = 49.6 bits (113), Expect = 5e-05
Identities = 78/342 (22%), Positives = 139/342 (40%), Gaps = 27/342 (7%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC 568
LD E++ LR+ + + A E+ L +A+ + LEG ++ ++ +E+
Sbjct: 88 LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETH 147
Query: 569 LQXXXXXXXXXXXXXXXXXXXXXXXIDELENE-NKSLRRQRVDNNVAHLQDELIAVKLRE 627
LQ I+EL+ E K++ Q+ + L +L + +
Sbjct: 148 LQSLQFDKEQMVAVTEANEALKKQ-IEELQQEARKAITEQK--QKMRRLGSDLTSA---Q 201
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
E K V LS Q L K+ A A Q + L +
Sbjct: 202 KEMKTKHKAYENAVGILSRRLQEALAA-KEAADAELGQLRAQGGSSDSSLALHERIQALE 260
Query: 688 ADMLKLDEE--LMTTRIREVEALT--ELKELRLKVMELETQVQVS---TNQLRRQDEEAR 740
A++ + L+ ++EV ALT EL+E R KV+ELE ++Q S +++R +E +
Sbjct: 261 AELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNK 320
Query: 741 LLRENLDAALQRERALQTRQREFQHKYADLE---SKAKYESMQANIRNMEDAQRIAELET 797
L L+ + L + + LE +K + + +Q N++ QR
Sbjct: 321 KLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQR-----K 375
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E + ++K+ V A + L + ++V L+EQVA K E
Sbjct: 376 EEEDRQMKHLVQALQASLEK----EKEKVNSLKEQVAAAKVE 413
Score = 43.2 bits (97), Expect = 0.004
Identities = 55/245 (22%), Positives = 115/245 (46%), Gaps = 30/245 (12%)
Query: 612 NVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSN---- 667
++ L ++ AV R+ E + +K L Q + E + + K++ AA V++
Sbjct: 360 DLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRR 419
Query: 668 ---VVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQ 724
S ++ KK L+A E + KL E +IRE + E+ + + ++ E Q
Sbjct: 420 HFKAASLELSEVKKELQAKEHL---VQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQ 476
Query: 725 VQVSTNQLRRQ-------DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYE 777
+Q+ QL Q ++E L+ +D Q+ER +Q+ +++ + + + + E
Sbjct: 477 LQLLQKQLDEQLSKQPVGNQEMENLKWEVD---QKEREIQSLKQQLD--LTEQQGRKELE 531
Query: 778 SMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELK 837
+Q ++N++ +A+ + +++ K K + A EL+NN ++ L +Q +LK
Sbjct: 532 GLQQLLQNVKSELEMAQEDLSMTQ-KDKFMLQAKVSELKNN-------MKTLLQQNQQLK 583
Query: 838 AEIMR 842
++ R
Sbjct: 584 LDLRR 588
Score = 42.7 bits (96), Expect = 0.006
Identities = 53/244 (21%), Positives = 112/244 (45%), Gaps = 20/244 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSA 688
E + +L+ LR+ ++ + HLQ QE A Q + + K ++ A+ +
Sbjct: 17 ETSETLEKLREELA-IKSGQVEHLQ---QETAALKKQMQKIKEQFLQQKVMVEAYRRDAT 72
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD- 747
+L EL TR R +ELKELR ++M++ + + + +L R E +R+++
Sbjct: 73 SKDQLISELKATRKR---LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMAD 129
Query: 748 -----AALQRER-ALQTRQREFQHKYADLESKAK-YESMQANIRNMEDAQRIAELETEVS 800
+ Q+ER ++T + Q + + + E+++ I ++ R A E +
Sbjct: 130 LEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQK 189
Query: 801 EYKLKNEVMATEGELRNNNMDDSDRV----RELQEQVAELKAEIMRLEAWKSRALGHTEL 856
+L +++ + + E++ + + V R LQE +A +A L +++ G ++
Sbjct: 190 MRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQG-GSSDS 248
Query: 857 SRAI 860
S A+
Sbjct: 249 SLAL 252
>AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ43937 fis, clone TESTI4013924. ).
Length = 623
Score = 49.6 bits (113), Expect = 5e-05
Identities = 53/249 (21%), Positives = 112/249 (44%), Gaps = 20/249 (8%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
ELEN K + Q +D + +Q+ + A+L + +L + + ++ +R+L E
Sbjct: 44 ELENGEKQ-QLQMLDR-LKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSEL 101
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
+Q D+ ++ +R W+ + + E + + V+ LT
Sbjct: 102 QQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKL----ERALEKQSETVDELTGKNNQI 157
Query: 716 LKVM-ELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ---REFQHKYADLE 771
LK EL+TQ+ + Q+ +E L + L +E L +++ R+ + ADLE
Sbjct: 158 LKEKDELKTQLYAALQQIENLRKE---LNDVLTKRALQEEELHSKEEKLRDIKSHQADLE 214
Query: 772 SKAKYESMQANIRNMEDAQRIAELETE--VSEYKLKNEVMATEGELRNNNMDDSDRVREL 829
+ K S+ R + ++ ++++++ V + L+ E+ EL+ + D ++ E+
Sbjct: 215 LEVK-NSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEI----AELKKSQAQDKAKLLEM 269
Query: 830 QEQVAELKA 838
QE + +L A
Sbjct: 270 QESIKDLSA 278
Score = 35.5 bits (78), Expect = 0.84
Identities = 48/259 (18%), Positives = 102/259 (39%), Gaps = 16/259 (6%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
RA EEE + + +++ ++ D++ + +LD I LE + + + QS ++ ++
Sbjct: 189 RALQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHL 248
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVD----NNVA 614
++ EL + ++L E ++ + D A
Sbjct: 249 EEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQA 308
Query: 615 HLQDE-----LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE----HKQEAPAAPVQ 665
+DE + +KL LKDL + + ++++QE K+E A
Sbjct: 309 KSRDEETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENH 368
Query: 666 SNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQV 725
+ K + + G+ + LK + +T + + E E K+L+LK L+ Q+
Sbjct: 369 IRTLKAESLEEKNMAKIHRGQ-LEKLKSQCDRLTEELTQNE--NENKKLKLKYQCLKDQL 425
Query: 726 QVSTNQLRRQDEEARLLRE 744
+ + ++E R + E
Sbjct: 426 EEREKHISIEEEHLRRMEE 444
Score = 32.7 bits (71), Expect = 5.9
Identities = 31/148 (20%), Positives = 69/148 (46%), Gaps = 7/148 (4%)
Query: 693 LDEELMTTRIREVEALTELKELR--LKVMELETQ-VQVSTNQLRRQDEEARLLRENLDAA 749
L EL ++++ L LKE++ E E + + ++L R E+A E +
Sbjct: 41 LTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSE 100
Query: 750 LQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLK-NEV 808
LQ+ AL + E + + DL+ KA+ Q +++ + + + + V E K N++
Sbjct: 101 LQQSEAL---KEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQI 157
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAEL 836
+ + EL+ ++ L++++ ++
Sbjct: 158 LKEKDELKTQLYAALQQIENLRKELNDV 185
>AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2
protein.
Length = 1390
Score = 49.6 bits (113), Expect = 5e-05
Identities = 78/342 (22%), Positives = 139/342 (40%), Gaps = 27/342 (7%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC 568
LD E++ LR+ + + A E+ L +A+ + LEG ++ ++ +E+
Sbjct: 876 LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETH 935
Query: 569 LQXXXXXXXXXXXXXXXXXXXXXXXIDELENE-NKSLRRQRVDNNVAHLQDELIAVKLRE 627
LQ I+EL+ E K++ Q+ + L +L + +
Sbjct: 936 LQSLQFDKEQMVAVTEANEALKKQ-IEELQQEARKAITEQK--QKMRRLGSDLTSA---Q 989
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
E K V LS Q L K+ A A Q + L +
Sbjct: 990 KEMKTKHKAYENAVGILSRRLQEALAA-KEAADAELGQLRAQGGSSDSSLALHERIQALE 1048
Query: 688 ADMLKLDEE--LMTTRIREVEALT--ELKELRLKVMELETQVQVS---TNQLRRQDEEAR 740
A++ + L+ ++EV ALT EL+E R KV+ELE ++Q S +++R +E +
Sbjct: 1049 AELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNK 1108
Query: 741 LLRENLDAALQRERALQTRQREFQHKYADLE---SKAKYESMQANIRNMEDAQRIAELET 797
L L+ + L + + LE +K + + +Q N++ QR
Sbjct: 1109 KLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQR-----K 1163
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E + ++K+ V A + L + ++V L+EQVA K E
Sbjct: 1164 EEEDRQMKHLVQALQASLEK----EKEKVNSLKEQVAAAKVE 1201
Score = 45.2 bits (102), Expect = 0.001
Identities = 79/379 (20%), Positives = 152/379 (40%), Gaps = 25/379 (6%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
+++ EGE E L R + ++Q L + LE E+ L T+
Sbjct: 673 RLEEFEGERER--LQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQ 730
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
A Q E+ LQ I L+NE L
Sbjct: 731 EAL-QSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGK 789
Query: 616 LQDELIAVKLREA--EANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
+ + A +L E E + +L+ LR+ ++ + HLQ QE A Q + +
Sbjct: 790 EELDRGARRLEEGTEETSETLEKLREELA-IKSGQVEHLQ---QETAALKKQMQKIKEQF 845
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
K ++ A+ + +L EL TR R +ELKELR ++M++ + + + +L
Sbjct: 846 LQQKVMVEAYRRDATSKDQLISELKATRKR---LDSELKELRQELMQVHGEKRTAEAELS 902
Query: 734 RQDEEARLLRENLD------AALQRER-ALQTRQREFQHKYADLESKAK-YESMQANIRN 785
R E +R+++ + Q+ER ++T + Q + + + E+++ I
Sbjct: 903 RLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEE 962
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRV----RELQEQVAELKAEIM 841
++ R A E + +L +++ + + E++ + + V R LQE +A +A
Sbjct: 963 LQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADA 1022
Query: 842 RLEAWKSRALGHTELSRAI 860
L +++ G ++ S A+
Sbjct: 1023 ELGQLRAQG-GSSDSSLAL 1040
Score = 43.2 bits (97), Expect = 0.004
Identities = 55/245 (22%), Positives = 115/245 (46%), Gaps = 30/245 (12%)
Query: 612 NVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSN---- 667
++ L ++ AV R+ E + +K L Q + E + + K++ AA V++
Sbjct: 1148 DLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRR 1207
Query: 668 ---VVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQ 724
S ++ KK L+A E + KL E +IRE + E+ + + ++ E Q
Sbjct: 1208 HFKAASLELSEVKKELQAKEHL---VQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQ 1264
Query: 725 VQVSTNQLRRQ-------DEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYE 777
+Q+ QL Q ++E L+ +D Q+ER +Q+ +++ + + + + E
Sbjct: 1265 LQLLQKQLDEQLSKQPVGNQEMENLKWEVD---QKEREIQSLKQQLD--LTEQQGRKELE 1319
Query: 778 SMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELK 837
+Q ++N++ +A+ + +++ K K + A EL+NN ++ L +Q +LK
Sbjct: 1320 GLQQLLQNVKSELEMAQEDLSMTQ-KDKFMLQAKVSELKNN-------MKTLLQQNQQLK 1371
Query: 838 AEIMR 842
++ R
Sbjct: 1372 LDLRR 1376
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 49.2 bits (112), Expect = 6e-05
Identities = 47/157 (29%), Positives = 77/157 (49%), Gaps = 15/157 (9%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
DE T + E +A K L +M+L+ + + ++ D E L E L ++L
Sbjct: 783 DEIFATAKENEKKA----KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 838
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 839 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 891
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 892 STAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 925
Score = 46.0 bits (104), Expect = 6e-04
Identities = 40/167 (23%), Positives = 85/167 (50%), Gaps = 9/167 (5%)
Query: 691 LKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
L+ + + M ++ ++E E +E + ++LE +V+ ++ E+ L+ ++ + L
Sbjct: 55 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLE---KVTAEAKIKKLEDEILVMDDQNNKL 111
Query: 751 QRERAL-QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVS-EYKLKNEV 808
+ER L + R + A+ E KAK + ++N ++ I+ELE + E K + E+
Sbjct: 112 SKERKLLEERISDLTTNLAEEEEKAKNLT---KLKNKHESM-ISELEVRLKKEEKSRQEL 167
Query: 809 MATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
+ +L + D +++ +LQ Q+AELK ++ + E AL +
Sbjct: 168 EKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 214
Score = 45.6 bits (103), Expect = 8e-04
Identities = 98/480 (20%), Positives = 196/480 (40%), Gaps = 48/480 (10%)
Query: 406 DMESILKYIQKELPLKAEADQAAFMNLAYSV--KVNP-KKMKKLEKEYTVIKTKEQGDIA 462
D+++ + ++ +L K E QAA L + K N KK+++LE + ++ + A
Sbjct: 187 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 246
Query: 463 VLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETF----ALDRE------ 512
++ R L + + Q RA+ E+E ALD E
Sbjct: 247 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 306
Query: 513 -VQALRRANVDMQQRLAVALDEIRSLEMTIAENNS----RQSSLEGTESASGQKHEELA- 566
VQ +R+ + + L L++ + + + +N + L G GQ +E+
Sbjct: 307 QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 366
Query: 567 --RCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSL---------RRQRVDNNVA- 614
+ L+ + +L+NE +S+ + ++ +VA
Sbjct: 367 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 426
Query: 615 ---HLQD--ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVV 669
LQD EL+ + R+ + N+S K LRQ + E S Q L E + + +
Sbjct: 427 LSSQLQDTQELLQEETRQ-KLNVSTK-LRQ-LEEERNSLQDQLDEEMEAKQNLERHISTL 483
Query: 670 SDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL----KVMELETQV 725
+ ++ KK L+ + A ++ EE +E+E LT+ E + K+ + + ++
Sbjct: 484 NIQLSDSKKKLQDF----ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 539
Query: 726 QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRN 785
Q + L + R L NL+ ++ L ++ KYAD +A+ E+ + +
Sbjct: 540 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 599
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SDRVRELQEQVAELKAEIMRLE 844
+ A+ + E E + N+++ E E ++ DD V EL++ L+ ++ ++
Sbjct: 600 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 659
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/258 (18%), Positives = 111/258 (43%), Gaps = 15/258 (5%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
+E + L + + + L+DE++ + + + + K L +R+S+L+ + ++
Sbjct: 76 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 135
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K +++S++ KK E +S L E+L R++E + +
Sbjct: 136 AKNLTKLKNKHESMISELEVRLKK-----EEKSRQEL---EKLK----RKLEG--DASDF 181
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
++ +L+ Q+ QL +++EE + LD + ++ + RE + +DL+
Sbjct: 182 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 241
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE-LQEQV 833
E N + ELE +E + + AT+ ELR + +++ L E+
Sbjct: 242 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 301
Query: 834 AELKAEIMRLEAWKSRAL 851
+A++ + ++A+
Sbjct: 302 RSHEAQVQEMRQKHAQAV 319
Score = 41.9 bits (94), Expect = 0.010
Identities = 49/228 (21%), Positives = 100/228 (43%), Gaps = 15/228 (6%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E +A+ ++K + + +L + Q +++ ++E A + +I AT K+ + +
Sbjct: 744 ELQADSAIKGREEAIKQLRKL-QAQMKDFQRELEDARASRD---EIFATAKENEKKAKSL 799
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRLKVME-------LETQVQVSTNQLRRQDEEA 739
AD+++L E+L +A E +EL ++ L+ + + ++ + +EE
Sbjct: 800 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 859
Query: 740 RLLRENLDAALQRERALQTRQREFQHKYADLESKA-KYES--MQANIRNMEDAQRIAELE 796
+ N++A R R + + ++ A S A K ES Q +N E ++ E+E
Sbjct: 860 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME 919
Query: 797 TEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
V K K+ + A E ++ RE Q LK + +L+
Sbjct: 920 GAVKS-KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 966
Score = 41.5 bits (93), Expect = 0.013
Identities = 59/264 (22%), Positives = 117/264 (44%), Gaps = 19/264 (7%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
ENE K+ + ++ ++ LQ++L A + +A+L ++L + ++ S S + LQ+ K+
Sbjct: 791 ENEKKA---KSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS-SLSGRNALQDEKR 846
Query: 658 EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLK 717
A Q + + + + + A R + E+L E + + R
Sbjct: 847 RLEARIAQ---LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-- 901
Query: 718 VMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ--REFQHKYADLES-KA 774
+LE Q + ++L + + ++ AAL+ + A Q +E + K A +S K
Sbjct: 902 -QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 960
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEY------KLKNEVMATEGELRNNNMDDSDRVRE 828
K + ++ + +ED +++AE E +E +LK ++ E E + N + RE
Sbjct: 961 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1020
Query: 829 LQEQVAELKAEIMRLEAWKSRALG 852
L E +A + A KS+ G
Sbjct: 1021 LDEATESNEAMGREVNALKSKLRG 1044
>X97053-1|CAA65765.1| 566|Homo sapiens plectin protein.
Length = 566
Score = 48.8 bits (111), Expect = 8e-05
Identities = 76/355 (21%), Positives = 144/355 (40%), Gaps = 28/355 (7%)
Query: 499 RAEGEE---ETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
R E EE ++ A + E R+A ++ +RL ++E R L + ++RQ L
Sbjct: 227 RREAEERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEA 286
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+ + EE A +D+L E ++ RR + A
Sbjct: 287 AQKRLQAEEKAHAF-----AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 341
Query: 616 LQDELIAVKL-REAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
+Q E A + R+ E LK + ++ Q ++ ++EA +
Sbjct: 342 VQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR------AQ 395
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+ LR + A+M K + T ++ + EL LRL++ E + Q + +L+R
Sbjct: 396 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 455
Query: 735 QDEEARLLRENLDAALQRERALQT--RQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
EA +AA QR + + R + + L+++ + E+ +R+ ++ QR
Sbjct: 456 LKAEA------TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRF 509
Query: 793 AELETE----VSEYKLKNEVMATE-GELRNNNMDDSDRVRELQEQVAELKAEIMR 842
+ E E V+E + V A E LR +D + R L E++ + K + ++
Sbjct: 510 LQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 564
Score = 47.2 bits (107), Expect = 3e-04
Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 13/205 (6%)
Query: 652 LQEHKQEAPAAPVQSNVVSD-IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
+Q+ +QE Q V D + + RA E ++ + E R R+VE
Sbjct: 302 VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQAR-RQVEEAER 360
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD- 769
LK+ + + Q Q + +LR++ E+ R + A R++ + E K+A+
Sbjct: 361 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 420
Query: 770 -LESKAKYESMQANIR-NMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDS-DRV 826
L KA+ E +R +E+ L E + +LK E ATE + + +++ V
Sbjct: 421 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ-RLKAE--ATEAARQRSQVEEELFSV 477
Query: 827 RELQEQVAELKAEIMRLEAWKSRAL 851
R E++++LKA R+EA ++RAL
Sbjct: 478 RVQMEELSKLKA---RIEA-ENRAL 498
Score = 37.9 bits (84), Expect = 0.16
Identities = 76/369 (20%), Positives = 143/369 (38%), Gaps = 35/369 (9%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESAS 558
+A EEE+ + + + A + LA +R+L AE RQ L E +
Sbjct: 15 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRAL----AEEAKRQRQL--AEEDA 68
Query: 559 GQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQD 618
++ E R L + E E EN+ LRR +D
Sbjct: 69 ARQRAEAERVL----AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA--------ED 116
Query: 619 ELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD-IMATPK 677
E + E +A D+ +R+++L ++ L+ K Q V + I+A
Sbjct: 117 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 176
Query: 678 KLLRAWEGRSADMLKL-------DEELMTTRIREVEALTELK---ELRLKVMELETQVQV 727
+A G++ L+L ++ L + E+EA + + E + E E +VQ
Sbjct: 177 SFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQK 236
Query: 728 ST---NQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIR 784
S + RQ + A E L A ++ R L+ R + + L +A + +QA +
Sbjct: 237 SLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 296
Query: 785 NMEDA--QRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVR-ELQEQVAELKAEIM 841
A Q+ EL+ + + + + + E E ++++ R + + + A+ + ++
Sbjct: 297 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVE 356
Query: 842 RLEAWKSRA 850
E K A
Sbjct: 357 EAERLKQSA 365
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 48.8 bits (111), Expect = 8e-05
Identities = 71/344 (20%), Positives = 147/344 (42%), Gaps = 18/344 (5%)
Query: 508 ALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELAR 567
ALD +++ ++R N +++Q +A ++I TI E + +E ++ EE
Sbjct: 637 ALD-QLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA 695
Query: 568 CLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLRE 627
L+ I E + E + L+R V +Q L A ++R
Sbjct: 696 ALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRN-YQRTVETMQSALDA-EVRR 753
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
A + LK ++ +L+E + ++Q A +V + T L A G+
Sbjct: 754 ANEAIRLK--KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 811
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
L E+L R E++ELR + + E +++ +L +E +LL
Sbjct: 812 ----DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 867
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAE---LETEVSEY-- 802
+ + ++ L+T + Q + D A+ +A + + DA +AE E + S +
Sbjct: 868 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK-KAITDAAMMAEELKKEQDTSAHLE 926
Query: 803 KLKNEVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLE 844
++K + T +L+ + +D++++ ++ ++Q+ +L+ I LE
Sbjct: 927 RMKKNLEQTVKDLQ-HRLDEAEQLALKGGKKQIQKLETRIRELE 969
Score = 41.9 bits (94), Expect = 0.010
Identities = 54/268 (20%), Positives = 111/268 (41%), Gaps = 5/268 (1%)
Query: 596 ELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+LE+E L++ ++ +A ++ E A + + L L + +++L+ + +
Sbjct: 88 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQE 147
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALT-ELK 712
H+Q + + V+ + T KL + E + L+ +++L R L +LK
Sbjct: 148 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS-LEQEKKLRVDLERNKRKLEGDLK 206
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
+ +++LE Q +L+++D E L+ ++ Q + +E Q + +LE
Sbjct: 207 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 266
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
+ + E + + ELE + V +T+ EL + ++R E+
Sbjct: 267 EIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEE 326
Query: 833 VAELKAEIMRLEAWKSRALGHTELSRAI 860
A L+ E M K A EL I
Sbjct: 327 -ATLQHEAMVATLRKKHADSVAELGEQI 353
Score = 41.1 bits (92), Expect = 0.017
Identities = 58/254 (22%), Positives = 105/254 (41%), Gaps = 18/254 (7%)
Query: 597 LENENKSLRRQRVDNNVAHLQ--DELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
L+ L R++ AH Q D+L A + + N + L Q+V +L S + QE
Sbjct: 131 LDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLE---QE 187
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
K + + D+ + +L D +LDE L + +++++
Sbjct: 188 KKLRVDLERNKRKLEGDLKLAQESILDL----ENDKQQLDERLKKKDFEYCQLQSKVEDE 243
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA 774
+ + L+ Q ++ Q R ++ E + E A + E+ RE + LE
Sbjct: 244 Q--TLGLQFQKKIKELQARIEELEEEIEAERATRA-KTEKQRSDYARELEELSERLEEAG 300
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVA 834
S Q + +A+ + +L ++ E L++E M LR + +D V EL EQ+
Sbjct: 301 GVTSTQIELNKKREAEFL-KLRRDLEEATLQHEAMVAT--LRKKH---ADSVAELGEQID 354
Query: 835 ELKAEIMRLEAWKS 848
L+ +LE KS
Sbjct: 355 NLQRVKQKLEKEKS 368
Score = 39.1 bits (87), Expect = 0.068
Identities = 46/246 (18%), Positives = 106/246 (43%), Gaps = 17/246 (6%)
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSE---------SWQRHLQEHKQEAPAAP 663
+ L++E+ A + A+ D + + ELSE S Q L + K+EA
Sbjct: 261 IEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNK-KREAEFLK 319
Query: 664 VQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELET 723
++ ++ + + + + + +L E++ + + + E E +L++ +L +
Sbjct: 320 LRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSS 379
Query: 724 QVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA-----KYES 778
++ + ++ R L + L A + +Q E + + L+++A + E
Sbjct: 380 SMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEE 439
Query: 779 MQANIRNMEDAQRIAELETEVSEYKLKNEVMATE--GELRNNNMDDSDRVRELQEQVAEL 836
++ + + +++ +TE + +L+ E A G ++ D D +RE E+ E
Sbjct: 440 KESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEG 499
Query: 837 KAEIMR 842
KAE+ R
Sbjct: 500 KAELQR 505
Score = 35.9 bits (79), Expect = 0.64
Identities = 83/429 (19%), Positives = 170/429 (39%), Gaps = 28/429 (6%)
Query: 401 DLLSLDMESILKYIQKELPLKAEADQAAFMNL-AYSVKVNP--KKMKKLEKEYTVIKTKE 457
+L LD E+I K +++ L+ EA Q A +L A KVN K KLE++ +++
Sbjct: 127 ELSGLD-ETIAKLTREKKALQ-EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL 184
Query: 458 QGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALR 517
+ + + L + R L+ + + + + E L +V+ +
Sbjct: 185 EQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQ 244
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
+ Q+++ I LE I + ++ E S ++ EEL+ L+
Sbjct: 245 TLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTS 304
Query: 578 XXXXXXXXXXXXXXXXIDELENEN-------KSLRRQRVDNNVAHLQDEL-----IAVKL 625
+LE +LR++ D+ VA L +++ + KL
Sbjct: 305 TQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS-VAELGEQIDNLQRVKQKL 363
Query: 626 RE--AEANLSLKDLRQRVSELSESWQ------RHLQEHKQEAPAAPVQSNVVSDIMATPK 677
+ +E L + DL + +S+S R L++ EA + + T K
Sbjct: 364 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 423
Query: 678 KLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQ-LRRQD 736
L+ G + L+ E +++ R +A T+ E + +E E + + + L+
Sbjct: 424 SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSR 483
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+ LLRE + + + LQ + + A +K + +++Q +E+A++
Sbjct: 484 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ-RTEELEEAKKKLAQR 542
Query: 797 TEVSEYKLK 805
+ SE +++
Sbjct: 543 LQDSEEQVE 551
Score = 32.3 bits (70), Expect = 7.8
Identities = 56/288 (19%), Positives = 115/288 (39%), Gaps = 17/288 (5%)
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC---LQXXXX 574
R D++++LA+ L+ AE +++LE TE A +EL +Q
Sbjct: 808 RGQEDLKEQLAIVERRANLLQ---AEVEELRATLEQTERARKLAEQELLDSNERVQLLHT 864
Query: 575 XXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLR-EAEANLS 633
E+E+ ++ R A ++A +L+ E + +
Sbjct: 865 QNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAH 924
Query: 634 LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKL 693
L+ +++ + + + Q L E +Q A + + + ++L EG +
Sbjct: 925 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ--IQKLETRIRELEFELEGEQKKNTES 982
Query: 694 DEELMTTRIREVEALTELKELR---LKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
+ L R E + +E R L++ +L ++QV +RQ EEA E +A L
Sbjct: 983 VKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEA---DEQANAHL 1039
Query: 751 QRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETE 798
+ R Q E + + AD+ ++++ ++A R+ ++ + E
Sbjct: 1040 TKFRKAQHELEEAEER-ADI-AESQVNKLRAKTRDFTSSRMVVHESEE 1085
>S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 330
Score = 48.8 bits (111), Expect = 8e-05
Identities = 47/157 (29%), Positives = 77/157 (49%), Gaps = 15/157 (9%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
DE T + E +A K L +M+L+ + + ++ D E L E L ++L
Sbjct: 27 DEIFATAKENEKKA----KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 82
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 83 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 135
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 136 TTAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 169
Score = 37.1 bits (82), Expect = 0.28
Identities = 41/184 (22%), Positives = 79/184 (42%), Gaps = 11/184 (5%)
Query: 671 DIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVME-------LET 723
+I AT K+ + + AD+++L E+L +A E +EL ++ L+
Sbjct: 28 EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD 87
Query: 724 QVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA-KYES--MQ 780
+ + ++ + +EE + N++A R R + + ++ A + A K ES Q
Sbjct: 88 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERTTAQKNESARQQ 147
Query: 781 ANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
+N E ++ E+E V K K+ + A E ++ RE Q LK +
Sbjct: 148 LERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 206
Query: 841 MRLE 844
+L+
Sbjct: 207 KKLK 210
>S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 296
Score = 48.8 bits (111), Expect = 8e-05
Identities = 47/157 (29%), Positives = 77/157 (49%), Gaps = 15/157 (9%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
DE T + E +A K L +M+L+ + + ++ D E L E L ++L
Sbjct: 27 DEIFATAKENEKKA----KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 82
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEG 813
ALQ +R + + A LE + + E Q N+ M D R A + E +L NE +ATE
Sbjct: 83 NALQDEKRRLEARIAQLEEELEEE--QGNMEAMSDRVRKATQQAE----QLSNE-LATER 135
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLE-AWKSR 849
N +S R ++L+ Q EL++++ +E A KS+
Sbjct: 136 TTAQKN--ESAR-QQLERQNKELRSKLHEMEGAVKSK 169
Score = 41.1 bits (92), Expect = 0.017
Identities = 59/264 (22%), Positives = 117/264 (44%), Gaps = 19/264 (7%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
ENE K+ + ++ ++ LQ++L A + +A+L ++L + ++ S S + LQ+ K+
Sbjct: 35 ENEKKA---KSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS-SLSGRNALQDEKR 90
Query: 658 EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLK 717
A Q + + + + + A R + E+L E + + R
Sbjct: 91 RLEARIAQ---LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERTTAQKNESAR-- 145
Query: 718 VMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ--REFQHKYADLES-KA 774
+LE Q + ++L + + ++ AAL+ + A Q +E + K A +S K
Sbjct: 146 -QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 204
Query: 775 KYESMQANIRNMEDAQRIAELETEVSEY------KLKNEVMATEGELRNNNMDDSDRVRE 828
K + ++ + +ED +++AE E +E +LK ++ E E + N + RE
Sbjct: 205 KDKKLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRE 264
Query: 829 LQEQVAELKAEIMRLEAWKSRALG 852
L E +A + A KS+ G
Sbjct: 265 LDEATESNEAMGREVNALKSKLRG 288
Score = 37.1 bits (82), Expect = 0.28
Identities = 41/184 (22%), Positives = 79/184 (42%), Gaps = 11/184 (5%)
Query: 671 DIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVME-------LET 723
+I AT K+ + + AD+++L E+L +A E +EL ++ L+
Sbjct: 28 EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD 87
Query: 724 QVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKA-KYES--MQ 780
+ + ++ + +EE + N++A R R + + ++ A + A K ES Q
Sbjct: 88 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERTTAQKNESARQQ 147
Query: 781 ANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
+N E ++ E+E V K K+ + A E ++ RE Q LK +
Sbjct: 148 LERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 206
Query: 841 MRLE 844
+L+
Sbjct: 207 KKLK 210
>L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein.
Length = 1898
Score = 48.8 bits (111), Expect = 8e-05
Identities = 55/228 (24%), Positives = 105/228 (46%), Gaps = 13/228 (5%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
+LE E + +++R + + Q+E +L+ E + L+QR+ SE R QE
Sbjct: 509 KLEEEERREQQERREQQLRREQEERREQRLKRQEEE---ERLQQRLR--SEQQLRREQEE 563
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRI-REVEALTELKEL 714
+ E + + ++L R E R +LK +EE R+ RE E E +
Sbjct: 564 RLEQLLKREEEKRLEQ-ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 622
Query: 715 RLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD-LESK 773
R +V LE Q + +L+R++ E E L + Q ER + +RE Q + L+ +
Sbjct: 623 REEVERLE-QEERRDERLKREEPEEERRHELLKSEEQEERRHEQLRREQQERREQRLKRE 681
Query: 774 AKYESMQANIRNMEDAQR----IAELETEVSEYKLKNEVMATEGELRN 817
+ E ++ ++ + +R +AE E E + ++K+ + + +L +
Sbjct: 682 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 729
Score = 42.3 bits (95), Expect = 0.007
Identities = 58/275 (21%), Positives = 113/275 (41%), Gaps = 27/275 (9%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQ 657
E E + ++R + Q+E + RE L ++ R++ + +R +E ++
Sbjct: 480 EEETERHEQERRKQQLKRDQEE----ERRERWLKLEEEERREQQERREQQLRREQEERRE 535
Query: 658 EAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR-- 715
+ + + + + ++L R E R +LK +EE + R + L +E R
Sbjct: 536 QRLKRQEEEERLQQRLRSEQQLRREQEERLEQLLKREEEKRLEQERREQRLKREQEERRD 595
Query: 716 --LKVMELETQVQVSTNQ-------LRRQDEEARLLRENLDAALQRERALQTRQREFQHK 766
LK E Q ++ Q L+R++ E E D L+RE + R+ E
Sbjct: 596 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRDERLKREEPEEERRHEL--- 652
Query: 767 YADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRV 826
L+S+ + E +R + +R L+ E E +L+ + E R + +
Sbjct: 653 ---LKSEEQEERRHEQLRREQQERREQRLKREEEEERLEQRLKREHEEERR----EQELA 705
Query: 827 RELQEQVAE-LKAEIMRLEAWKSRALGHTELSRAI 860
E QEQ E +K+ I + + W+ + S+ +
Sbjct: 706 EEEQEQARERIKSRIPKWQ-WQLESEADARQSKVL 739
Score = 39.9 bits (89), Expect = 0.039
Identities = 58/262 (22%), Positives = 105/262 (40%), Gaps = 12/262 (4%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
+LE E RRQ+ L + + E + L +D ++R EL Q +
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAE---GEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE 184
Query: 656 KQEAPAAPVQSNVVSDIMATP-KKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKEL 714
++ A +QS + P ++ LR E +E+ R R+ E +E
Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK 244
Query: 715 RLKVMEL-----ETQVQVSTNQLRRQ-DEEARLLRENLDAALQRERALQTRQREFQHKYA 768
+ E E ++Q Q +R+ EE LR+ L+RER + +Q++ +
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ 304
Query: 769 DLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE 828
L K + E + E +R E + E E +L+ E + ++ R ++
Sbjct: 305 QLRRKQEEERREQQEERREQQER-REQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 829 L-QEQVAELKAEIMRLEAWKSR 849
L +EQ E + + +R E + R
Sbjct: 364 LRREQEEERREQQLRREQEEER 385
Score = 38.3 bits (85), Expect = 0.12
Identities = 55/264 (20%), Positives = 115/264 (43%), Gaps = 21/264 (7%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELIAVKLR-EAEANLSLKDLRQRVSELSESWQ--RHLQE 654
+ E + + +R + + Q+E +LR E E + LR+ E Q R +E
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQEE 383
Query: 655 HKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTR-IREVEALTELKE 713
++E Q + ++L R + R L+ +++L + +R + L ++
Sbjct: 384 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 443
Query: 714 LRLKVME----LETQVQVSTNQLRRQDEEAR--LLRENLDAALQRERALQTRQREFQH-- 765
LR + E + + + +L+R+ EE R L RE ++ER Q +R+ +
Sbjct: 444 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 503
Query: 766 -----KYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM 820
K + E + + E + +R ++ +R L+ + E +L+ + +E +LR
Sbjct: 504 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR-LRSEQQLRR--- 559
Query: 821 DDSDRVRELQEQVAELKAEIMRLE 844
+ +R+ +L ++ E + E R E
Sbjct: 560 EQEERLEQLLKREEEKRLEQERRE 583
Score = 37.5 bits (83), Expect = 0.21
Identities = 56/250 (22%), Positives = 97/250 (38%), Gaps = 16/250 (6%)
Query: 600 ENKSLRRQ------RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELS---ESWQR 650
E + LRRQ R D + ++E + + E + + +D + R+ E + +R
Sbjct: 1492 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1551
Query: 651 HLQEHKQEAPAAPVQSNVVSDI--MATPKKLLRAWEGRSADMLKLDEELMTT--RIREVE 706
E +Q+ Q + + ++LL+ E + + D + + ++R E
Sbjct: 1552 KFMEDEQQLRRQEGQQQLRQEDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1611
Query: 707 ALTELKELR-LKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
+L+ R K E E +Q Q R+ E R RE ++ER + Q E Q
Sbjct: 1612 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1671
Query: 766 KYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDR 825
+ +LE K + E E +R + E +L+ E E +LR D R
Sbjct: 1672 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE--REEQQLRRQERDRKFR 1729
Query: 826 VRELQEQVAE 835
E Q E
Sbjct: 1730 EEEQLRQGRE 1739
Score = 37.1 bits (82), Expect = 0.28
Identities = 40/236 (16%), Positives = 97/236 (41%), Gaps = 6/236 (2%)
Query: 598 ENENKSLRRQRVDNNVAHLQDELI-AVKLREAEANLSLKDLRQRVSELSESWQRHLQEHK 656
E E + +++ + H +E +LR E L +LR++ E + +R Q+
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRE----LLELRRKGREEKQQQRRERQDRV 237
Query: 657 QEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL 716
+ + + +KL R ++ + +E+L +E+ + +E +
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
+ + E Q++ + RR+ +E R ++ + R Q R+ + + + L + +
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 777 ESMQANI-RNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQE 831
E + + R E+ +R +L E E + + ++ + R + ++R Q+
Sbjct: 358 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 413
Score = 36.7 bits (81), Expect = 0.36
Identities = 49/249 (19%), Positives = 100/249 (40%), Gaps = 13/249 (5%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
E + E + +R R + + Q+E + + E ++ R++ E E R QE
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEE---ERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEG-RSADMLKLD--EELMTTRIREVEALTELK 712
++E Q + ++L R E R L+ + EE ++R + L +
Sbjct: 346 RREQQLRREQEEERRE-----QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 400
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
+LR + Q QLRR+ + R + + L+RE+ L+ Q E +H+ +
Sbjct: 401 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 460
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNN--NMDDSDRVRELQ 830
+ + + + +R E E E + + E E R +++ +R + +
Sbjct: 461 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 520
Query: 831 EQVAELKAE 839
+ +L+ E
Sbjct: 521 RREQQLRRE 529
Score = 36.3 bits (80), Expect = 0.48
Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 5/160 (3%)
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQD-EEARLLR---E 744
D + +EE R RE E ++L+ + + + ++Q QLR+ + +E R R E
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 745 NLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKL 804
L+RE+ L+ +Q E + + + E + + E + E R + E + +
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQE-ERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 805 KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
+ E E +LR ++ + +EQ E + + +R E
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 393
Score = 35.1 bits (77), Expect = 1.1
Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 12/165 (7%)
Query: 701 RIREVEALTELKELRLKVMELETQVQVSTNQLRRQDE----EARLLRENLDAALQRERAL 756
+ RE E L + +E L+ + + Q Q R++DE E +LLRE + +R L
Sbjct: 1006 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE-----REKRRL 1060
Query: 757 QTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEV---SEYKLKNEVMATEG 813
Q R+R+++ + + + + + R ++ +R E E+ E L+ E
Sbjct: 1061 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1120
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSR 858
+ R + + +++ +EQ+ + E R + + + EL R
Sbjct: 1121 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEELQR 1165
Score = 34.3 bits (75), Expect = 1.9
Identities = 68/350 (19%), Positives = 126/350 (36%), Gaps = 11/350 (3%)
Query: 496 QVDRAEGEEETFALDR-EVQALRRANVDMQQRLAVALDEIRSLEMTIAENNS-RQSSLEG 553
Q + E EE+ L+R E++ R+ QQRL R E E R+ E
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 554 TESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNV 613
E ++ ++L R + +E E + R Q +
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQEEERRE 387
Query: 614 AHLQDE--LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSD 671
L+ E L + E L + +R +L Q ++ + + + +
Sbjct: 388 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 447
Query: 672 IMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQ 731
+ E R + + EE RE E +E R + ++ + + +
Sbjct: 448 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 507
Query: 732 LRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQR 791
L+ ++EE R +E + L+RE Q +RE + K + E + + E +R
Sbjct: 508 LKLEEEERREQQERREQQLRRE---QEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 564
Query: 792 IAELETEVSEYKLKNEVMATEGELRNNNMDDSDRV--RELQEQVAELKAE 839
+ +L E +L+ E E L+ + D++ RE + + LK E
Sbjct: 565 LEQLLKREEEKRLEQE--RREQRLKREQEERRDQLLKREEERRQQRLKRE 612
Score = 33.5 bits (73), Expect = 3.4
Identities = 48/247 (19%), Positives = 90/247 (36%), Gaps = 13/247 (5%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
E E + ++ RR R L E K R E + ++ Q + E E +
Sbjct: 1258 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLLRQERD 1317
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGR---SADMLKLDEELMTTRIREVEALTELK 712
++ + + ++L E + L+L+E + R+ + E
Sbjct: 1318 RKFREEELLHQEQGRKFLEEEQRLREERERKFLKEEQQLRLEEREQLRQDRDRKFREE-- 1375
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQR-------ERALQTRQREFQH 765
E +L E + + + Q+RRQ+ E + L E +R E+ LQ R+ + H
Sbjct: 1376 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1435
Query: 766 KYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDR 825
+ + + K E Q + + R EL ++ E K E + R ++
Sbjct: 1436 R-QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1494
Query: 826 VRELQEQ 832
QE+
Sbjct: 1495 QLRRQER 1501
Score = 33.5 bits (73), Expect = 3.4
Identities = 67/335 (20%), Positives = 125/335 (37%), Gaps = 11/335 (3%)
Query: 498 DRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESA 557
DR EEE +RE Q L R D + RL + E E+ + EG +
Sbjct: 1510 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1569
Query: 558 --SGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
+K E + LQ + + R R
Sbjct: 1570 RQEDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1629
Query: 616 LQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA- 674
L E +LR E + ++ Q++ E ++ LQE +Q + + +
Sbjct: 1630 LLQEGEEQQLRRQERDRKFREEEQQLRR-QERERKFLQEEQQLRRQELERKFREEEQLRQ 1688
Query: 675 -TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
T ++ LR E R +L+ +E+L R E + + ++ + + E Q + QLR
Sbjct: 1689 ETEQEQLRRQE-RYRKILE-EEQLRPER-EEQQLRRQERDRKFREEEQLRQGR-EEQQLR 1744
Query: 734 RQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
Q+ + + E + E+ L+ +QR+ ++++ E + + E + +R D Q A
Sbjct: 1745 SQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE--EEQLQLEEQEQRLRQERDRQYRA 1802
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRE 828
E + E + E + E + + ++RE
Sbjct: 1803 EEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1837
Score = 33.5 bits (73), Expect = 3.4
Identities = 40/148 (27%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMEL----ETQVQVSTNQ--LRRQDEEARLLRENLD 747
+E+ + + RE + L E ++LR + +E E Q++ T Q LRRQ+ ++L E
Sbjct: 1651 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE-Q 1709
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNE 807
+RE Q R++E K+ + E + + + +R+ E ++ E E +L+ E
Sbjct: 1710 LRPEREEQ-QLRRQERDRKFRE-EEQLRQGREEQQLRSQESDRKFRE------EEQLRQE 1761
Query: 808 VMATEGELRNNNMDDSDRVRELQEQVAE 835
E +LR D R E Q Q+ E
Sbjct: 1762 --REEQQLRPQQRDGKYRWEEEQLQLEE 1787
Score = 32.3 bits (70), Expect = 7.8
Identities = 50/221 (22%), Positives = 93/221 (42%), Gaps = 15/221 (6%)
Query: 627 EAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGR 686
E E L ++ Q++ E + Q + +QE + + + L A +
Sbjct: 853 EEEEQLQRRERAQQLQEEEDGLQEDQERRRQEQRRDQKWRWQLEEERKRRRHTLYA-KPA 911
Query: 687 SADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENL 746
+ L+ +++L+ E++ E +E R + E E Q + QL Q EE +LLRE
Sbjct: 912 LQEQLRKEQQLLQEEEEELQR--EEREKRRR-QEQERQYR-EEEQL--QQEEEQLLREER 965
Query: 747 DAALQRERALQTRQ-REFQHKYADL--ESKAKYESMQANIRNMEDAQRIAELETEVSEYK 803
+ ++ER Q R+ ++ Q K L E K + + E+ + E E + E +
Sbjct: 966 EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1025
Query: 804 LKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLE 844
K E + R D +++ +EQ+ + E RL+
Sbjct: 1026 EKRRRQEWERQYRK-----KDELQQEEEQLLREEREKRRLQ 1061
>AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 48.8 bits (111), Expect = 8e-05
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 342 IEELEETNKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 399
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 400 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 459
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 460 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 519
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 520 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 578
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 579 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 621
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E+ ++LQ+ ++E A S++++++ K++L
Sbjct: 330 QLRLKLVGLTQRIEELEET-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 388
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 389 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 447
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 448 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 507
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 508 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
Score = 40.3 bits (90), Expect = 0.030
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 630 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 685
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ +V LK +I L
Sbjct: 686 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 734
>AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 48.8 bits (111), Expect = 8e-05
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 243 IEELEETNKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 300
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 301 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 360
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 361 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 420
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 421 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 479
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 480 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 522
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E+ ++LQ+ ++E A S++++++ K++L
Sbjct: 231 QLRLKLVGLTQRIEELEET-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 289
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 290 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 348
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 349 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 408
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 409 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 460
Score = 40.3 bits (90), Expect = 0.030
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 531 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 586
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ +V LK +I L
Sbjct: 587 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 635
>AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 48.8 bits (111), Expect = 8e-05
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 342 IEELEETNKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 399
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 400 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 459
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 460 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 519
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 520 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 578
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 579 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 621
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E+ ++LQ+ ++E A S++++++ K++L
Sbjct: 330 QLRLKLVGLTQRIEELEET-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 388
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 389 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 447
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 448 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 507
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 508 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
Score = 40.3 bits (90), Expect = 0.030
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 630 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 685
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ +V LK +I L
Sbjct: 686 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 734
>AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 48.8 bits (111), Expect = 8e-05
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 243 IEELEETNKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 300
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 301 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 360
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 361 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 420
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 421 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 479
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 480 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 522
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E+ ++LQ+ ++E A S++++++ K++L
Sbjct: 231 QLRLKLVGLTQRIEELEET-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 289
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 290 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 348
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 349 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 408
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 409 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 460
Score = 40.3 bits (90), Expect = 0.030
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 531 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 586
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ +V LK +I L
Sbjct: 587 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 635
>AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens
cDNA FLJ14799 fis, clone NT2RP4001351, weakly similar to
Human ovarian cancer downregulated myosin heavy chain
homolog ).
Length = 965
Score = 48.8 bits (111), Expect = 8e-05
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 94 IEELEETNKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 151
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 152 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 211
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 212 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 271
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 272 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 330
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 331 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 373
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E+ ++LQ+ ++E A S++++++ K++L
Sbjct: 82 QLRLKLVGLTQRIEELEET-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 140
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 141 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 199
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 200 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 259
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 260 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 311
Score = 38.7 bits (86), Expect = 0.090
Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 382 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 437
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ V LK +I L
Sbjct: 438 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAGVQALKEKIHEL 486
>AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein.
Length = 1213
Score = 48.8 bits (111), Expect = 8e-05
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 342 IEELEETNKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 399
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 400 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 459
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 460 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 519
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 520 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 578
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 579 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 621
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E+ ++LQ+ ++E A S++++++ K++L
Sbjct: 330 QLRLKLVGLTQRIEELEET-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 388
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 389 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 447
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 448 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 507
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 508 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
Score = 40.3 bits (90), Expect = 0.030
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 630 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 685
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ +V LK +I L
Sbjct: 686 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 734
>AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein.
Length = 1140
Score = 48.8 bits (111), Expect = 8e-05
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 269 IEELEETNKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 326
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 327 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 386
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 387 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 446
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 447 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 505
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 506 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 548
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E+ ++LQ+ ++E A S++++++ K++L
Sbjct: 257 QLRLKLVGLTQRIEELEET-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 315
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 316 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 374
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 375 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 434
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 435 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 486
Score = 40.3 bits (90), Expect = 0.030
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 557 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 612
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ +V LK +I L
Sbjct: 613 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 661
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 48.4 bits (110), Expect = 1e-04
Identities = 48/261 (18%), Positives = 115/261 (44%), Gaps = 13/261 (4%)
Query: 594 IDELENENKSLRRQ---RVDNNVAHLQDELIAVKLREAEANLS-----LKDLRQRVSELS 645
+++ E EN LR + R +N + + + + ++ +S L+DL + + L
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLK 409
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV 705
+ +E ++E V + + ++L + A +L ++ +
Sbjct: 410 SNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIG 469
Query: 706 EALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
+ EL +++ L+T+++ TNQ + +L+E+L A QR LQT +
Sbjct: 470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Query: 766 KYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SD 824
+ + E+ ++ Q I++M A+ E+ + K +V + + +++ +
Sbjct: 530 RLEEKETMLNKKTKQ--IQDM--AEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQE 585
Query: 825 RVRELQEQVAELKAEIMRLEA 845
++R+ ++Q++ LK + L+A
Sbjct: 586 QLRDKEKQMSSLKERVKSLQA 606
Score = 41.5 bits (93), Expect = 0.013
Identities = 50/273 (18%), Positives = 126/273 (46%), Gaps = 24/273 (8%)
Query: 595 DELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHL 652
+EL+ + L+ + +V ++ EL+A++ + D +Q + L ES L
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKES----L 510
Query: 653 QEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+Q A + + + + + +L + DM + ++ I +++ + ++K
Sbjct: 511 TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE-EKGTQAGEIHDLKDMLDVK 569
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRE----------NLDAALQR-ERALQTRQR 761
E ++ V L+ +++ QLR ++++ L+E N D AL E AL ++R
Sbjct: 570 ERKVNV--LQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 627
Query: 762 EFQH--KYADLESKAKYESMQANIRNMED-AQRIAELETEVSEYKLK-NEVMATEGELRN 817
+ + D + + K E + ++++D ++++ L+ ++SE + ++ L +
Sbjct: 628 TIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLAS 687
Query: 818 NNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
+ + R++ L+ + + K E +++E+ +A
Sbjct: 688 SGLKKDSRLKTLEIALEQKKEECLKMESQLKKA 720
Score = 35.1 bits (77), Expect = 1.1
Identities = 36/172 (20%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Query: 686 RSADMLKLDEELMTTRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRE 744
R ++LK E + +++ L ++K+ KV L+ + QV + + EEAR +
Sbjct: 760 RLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 819
Query: 745 NL-DAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI-AELETE---V 799
NL D++ Q + +L+ + + L + + + + E++ R AE + E +
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 800 SEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRAL 851
+ K+K E+ + + +L + +++ L AE + + + K AL
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEAL 931
Score = 35.1 bits (77), Expect = 1.1
Identities = 48/216 (22%), Positives = 87/216 (40%), Gaps = 13/216 (6%)
Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSE----LSESWQRHLQEH 655
E R ++++ LQD L R E +L++ Q +E L++
Sbjct: 812 EEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAE 871
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE-- 713
KQ V ++ + KL + + L L R + +E + E+K+
Sbjct: 872 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTN-LRAERRKHLEEVLEMKQEA 930
Query: 714 LRLKVMELETQV---QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADL 770
L + E + + ++S+++ + Q+E A L RE Q ++ Q R + Y D
Sbjct: 931 LLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDD 990
Query: 771 ESKAKYESMQANIRNMED--AQRIAELETEVSEYKL 804
K+ + S Q N + D Q + EL+ S+ KL
Sbjct: 991 HFKSSH-SNQTNHKPSPDQIIQPLLELDQNRSKLKL 1025
Score = 33.1 bits (72), Expect = 4.5
Identities = 28/132 (21%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
Query: 710 ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD 769
EL LR + E+E +++ L +DE + L E L + +A + E + A+
Sbjct: 280 ELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATE-EDHERTRRLAE 338
Query: 770 LESKAKYESMQANIRNMEDAQRIAELET--EVSEYKLKNEVMATEGELRNNNMDDSDR-V 826
E + + E++ E+ E + K + + T E++++ + +R +
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGL 398
Query: 827 RELQEQVAELKA 838
R+L+E++ LK+
Sbjct: 399 RDLEEEIQMLKS 410
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 48.4 bits (110), Expect = 1e-04
Identities = 48/261 (18%), Positives = 115/261 (44%), Gaps = 13/261 (4%)
Query: 594 IDELENENKSLRRQ---RVDNNVAHLQDELIAVKLREAEANLS-----LKDLRQRVSELS 645
+++ E EN LR + R +N + + + + ++ +S L+DL + + L
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLK 409
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV 705
+ +E ++E V + + ++L + A +L ++ +
Sbjct: 410 SNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIG 469
Query: 706 EALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
+ EL +++ L+T+++ TNQ + +L+E+L A QR LQT +
Sbjct: 470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Query: 766 KYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SD 824
+ + E+ ++ Q I++M A+ E+ + K +V + + +++ +
Sbjct: 530 RLEEKETMLNKKTKQ--IQDM--AEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQE 585
Query: 825 RVRELQEQVAELKAEIMRLEA 845
++R+ ++Q++ LK + L+A
Sbjct: 586 QLRDKEKQMSSLKERVKSLQA 606
Score = 41.5 bits (93), Expect = 0.013
Identities = 50/273 (18%), Positives = 126/273 (46%), Gaps = 24/273 (8%)
Query: 595 DELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHL 652
+EL+ + L+ + +V ++ EL+A++ + D +Q + L ES L
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKES----L 510
Query: 653 QEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+Q A + + + + + +L + DM + ++ I +++ + ++K
Sbjct: 511 TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE-EKGTQAGEIHDLKDMLDVK 569
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRE----------NLDAALQR-ERALQTRQR 761
E ++ V L+ +++ QLR ++++ L+E N D AL E AL ++R
Sbjct: 570 ERKVNV--LQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 627
Query: 762 EFQH--KYADLESKAKYESMQANIRNMED-AQRIAELETEVSEYKLK-NEVMATEGELRN 817
+ + D + + K E + ++++D ++++ L+ ++SE + ++ L +
Sbjct: 628 TIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLAS 687
Query: 818 NNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
+ + R++ L+ + + K E +++E+ +A
Sbjct: 688 SGLKKDSRLKTLEIALEQKKEECLKMESQLKKA 720
Score = 35.1 bits (77), Expect = 1.1
Identities = 36/172 (20%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Query: 686 RSADMLKLDEELMTTRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRE 744
R ++LK E + +++ L ++K+ KV L+ + QV + + EEAR +
Sbjct: 760 RLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 819
Query: 745 NL-DAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI-AELETE---V 799
NL D++ Q + +L+ + + L + + + + E++ R AE + E +
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 800 SEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRAL 851
+ K+K E+ + + +L + +++ L AE + + + K AL
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEAL 931
Score = 35.1 bits (77), Expect = 1.1
Identities = 48/216 (22%), Positives = 87/216 (40%), Gaps = 13/216 (6%)
Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSE----LSESWQRHLQEH 655
E R ++++ LQD L R E +L++ Q +E L++
Sbjct: 812 EEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAE 871
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE-- 713
KQ V ++ + KL + + L L R + +E + E+K+
Sbjct: 872 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTN-LRAERRKHLEEVLEMKQEA 930
Query: 714 LRLKVMELETQV---QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADL 770
L + E + + ++S+++ + Q+E A L RE Q ++ Q R + Y D
Sbjct: 931 LLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDD 990
Query: 771 ESKAKYESMQANIRNMED--AQRIAELETEVSEYKL 804
K+ + S Q N + D Q + EL+ S+ KL
Sbjct: 991 HFKSSH-SNQTNHKPSPDQIIQPLLELDQNRSKLKL 1025
Score = 33.1 bits (72), Expect = 4.5
Identities = 28/132 (21%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
Query: 710 ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD 769
EL LR + E+E +++ L +DE + L E L + +A + E + A+
Sbjct: 280 ELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATE-EDHERTRRLAE 338
Query: 770 LESKAKYESMQANIRNMEDAQRIAELET--EVSEYKLKNEVMATEGELRNNNMDDSDR-V 826
E + + E++ E+ E + K + + T E++++ + +R +
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGL 398
Query: 827 RELQEQVAELKA 838
R+L+E++ LK+
Sbjct: 399 RDLEEEIQMLKS 410
>AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein.
Length = 1498
Score = 48.4 bits (110), Expect = 1e-04
Identities = 77/342 (22%), Positives = 142/342 (41%), Gaps = 27/342 (7%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC 568
LD E++ LR+ + + A E+ L +A+ + LEG ++ ++ +E+
Sbjct: 876 LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEVETH 935
Query: 569 LQXXXXXXXXXXXXXXXXXXXXXXXIDELENE-NKSLRRQRVDNNVAHLQDELIAVKLRE 627
LQ I+EL+ E K++ Q+ + L +L + +
Sbjct: 936 LQSLQFDKEQMVAVTEANEALKKQ-IEELQQEARKAITEQK--QKMRRLGSDLTSA---Q 989
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQ-EAPAAPVQSNV-VSDIMATPKKLLRAWEG 685
E K V LS Q L + +A +++ SD + ++A E
Sbjct: 990 KEMKTKHKAYENAVGILSRRLQEALAAREAADAELGQLRAQGGSSDSSLALHERIQALEA 1049
Query: 686 RSADMLKLDEELMTTRIREVEALT--ELKELRLKVMELETQVQVS---TNQLRRQDEEAR 740
+ + L+ ++EV ALT EL+E R KV+ELE ++Q S +++R +E +
Sbjct: 1050 E-LQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNK 1108
Query: 741 LLRENLDAALQRERALQTRQREFQHKYADLE---SKAKYESMQANIRNMEDAQRIAELET 797
L L+ + L + + LE +K + + +Q N++ QR
Sbjct: 1109 KLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQR-----K 1163
Query: 798 EVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
E + ++K+ V A + L + ++V L+EQVA K E
Sbjct: 1164 EEEDRQMKHLVQALQASLEK----EKEKVNSLKEQVAAAKVE 1201
Score = 44.8 bits (101), Expect = 0.001
Identities = 79/379 (20%), Positives = 152/379 (40%), Gaps = 25/379 (6%)
Query: 496 QVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTE 555
+++ EGE E L R + ++Q L + LE E+ L T+
Sbjct: 673 RLEEFEGERER--LQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQ 730
Query: 556 SASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAH 615
A Q E+ LQ I L+NE L
Sbjct: 731 EAL-QSREQSLDALQTRYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGK 789
Query: 616 LQDELIAVKLREA--EANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIM 673
+ + A +L E E + +L+ LR+ ++ + HLQ QE A Q + +
Sbjct: 790 EELDRGARRLEEGTEETSETLEKLREELA-IKSGQVEHLQ---QETAALKKQMQKIKEQF 845
Query: 674 ATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLR 733
K ++ A+ + +L EL TR R +ELKELR ++M++ + + + +L
Sbjct: 846 LQQKVMVEAYRRDATSKDQLISELKATRKR---LDSELKELRQELMQVHGEKRTAEAELS 902
Query: 734 RQDEEARLLRENLD------AALQRER-ALQTRQREFQHKYADLESKAK-YESMQANIRN 785
R E +R+++ + Q+ER ++T + Q + + + E+++ I
Sbjct: 903 RLHREVAQVRQHMADLEGHLQSAQKERDEVETHLQSLQFDKEQMVAVTEANEALKKQIEE 962
Query: 786 MEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRV----RELQEQVAELKAEIM 841
++ R A E + +L +++ + + E++ + + V R LQE +A +A
Sbjct: 963 LQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAREAADA 1022
Query: 842 RLEAWKSRALGHTELSRAI 860
L +++ G ++ S A+
Sbjct: 1023 ELGQLRAQG-GSSDSSLAL 1040
Score = 41.5 bits (93), Expect = 0.013
Identities = 55/242 (22%), Positives = 111/242 (45%), Gaps = 24/242 (9%)
Query: 612 NVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSN---- 667
++ L ++ AV R+ E + +K L Q + E + + K++ AA V++
Sbjct: 1148 DLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRR 1207
Query: 668 ---VVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQ 724
S ++ KK L+A E + KL E +IRE + E+ + + ++ E Q
Sbjct: 1208 HFKAASLELSEVKKELQAKEHL---VQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQ 1264
Query: 725 VQVSTNQLRRQ---DEEARLLRENLDAAL-QRERALQTRQREFQHKYADLESKAKYESMQ 780
+Q+ QL Q ENL + Q+ER +Q+ +++ + + + E +Q
Sbjct: 1265 LQLLQKQLDEQLSKQPAGNQEMENLKWEVDQKEREIQSLKQQLD--LTEQQGWKELEGLQ 1322
Query: 781 ANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
++N++ +A+ + +++ K K + A EL+NN ++ L +Q +LK ++
Sbjct: 1323 QLLQNVKSELEMAQEDLSMTQ-KDKFMLQAKVSELKNN-------MKTLLQQNQQLKLDL 1374
Query: 841 MR 842
R
Sbjct: 1375 RR 1376
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 48.4 bits (110), Expect = 1e-04
Identities = 48/261 (18%), Positives = 115/261 (44%), Gaps = 13/261 (4%)
Query: 594 IDELENENKSLRRQ---RVDNNVAHLQDELIAVKLREAEANLS-----LKDLRQRVSELS 645
+++ E EN LR + R +N + + + + ++ +S L+DL + + L
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLK 409
Query: 646 ESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREV 705
+ +E ++E V + + ++L + A +L ++ +
Sbjct: 410 SNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIG 469
Query: 706 EALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQH 765
+ EL +++ L+T+++ TNQ + +L+E+L A QR LQT +
Sbjct: 470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Query: 766 KYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDD-SD 824
+ + E+ ++ Q I++M A+ E+ + K +V + + +++ +
Sbjct: 530 RLEEKETMLNKKTKQ--IQDM--AEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQE 585
Query: 825 RVRELQEQVAELKAEIMRLEA 845
++R+ ++Q++ LK + L+A
Sbjct: 586 QLRDKEKQMSSLKERVKSLQA 606
Score = 41.5 bits (93), Expect = 0.013
Identities = 50/273 (18%), Positives = 126/273 (46%), Gaps = 24/273 (8%)
Query: 595 DELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHL 652
+EL+ + L+ + +V ++ EL+A++ + D +Q + L ES L
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKES----L 510
Query: 653 QEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELK 712
+Q A + + + + + +L + DM + ++ I +++ + ++K
Sbjct: 511 TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE-EKGTQAGEIHDLKDMLDVK 569
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRE----------NLDAALQR-ERALQTRQR 761
E ++ V L+ +++ QLR ++++ L+E N D AL E AL ++R
Sbjct: 570 ERKVNV--LQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 627
Query: 762 EFQH--KYADLESKAKYESMQANIRNMED-AQRIAELETEVSEYKLK-NEVMATEGELRN 817
+ + D + + K E + ++++D ++++ L+ ++SE + ++ L +
Sbjct: 628 TIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLAS 687
Query: 818 NNMDDSDRVRELQEQVAELKAEIMRLEAWKSRA 850
+ + R++ L+ + + K E +++E+ +A
Sbjct: 688 SGLKKDSRLKTLEIALEQKKEECLKMESQLKKA 720
Score = 35.1 bits (77), Expect = 1.1
Identities = 36/172 (20%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Query: 686 RSADMLKLDEELMTTRIREVEALT-ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRE 744
R ++LK E + +++ L ++K+ KV L+ + QV + + EEAR +
Sbjct: 760 RLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 819
Query: 745 NL-DAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI-AELETE---V 799
NL D++ Q + +L+ + + L + + + + E++ R AE + E +
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 800 SEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRAL 851
+ K+K E+ + + +L + +++ L AE + + + K AL
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEAL 931
Score = 35.1 bits (77), Expect = 1.1
Identities = 48/216 (22%), Positives = 87/216 (40%), Gaps = 13/216 (6%)
Query: 600 ENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSE----LSESWQRHLQEH 655
E R ++++ LQD L R E +L++ Q +E L++
Sbjct: 812 EEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAE 871
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE-- 713
KQ V ++ + KL + + L L R + +E + E+K+
Sbjct: 872 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTN-LRAERRKHLEEVLEMKQEA 930
Query: 714 LRLKVMELETQV---QVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADL 770
L + E + + ++S+++ + Q+E A L RE Q ++ Q R + Y D
Sbjct: 931 LLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDD 990
Query: 771 ESKAKYESMQANIRNMED--AQRIAELETEVSEYKL 804
K+ + S Q N + D Q + EL+ S+ KL
Sbjct: 991 HFKSSH-SNQTNHKPSPDQIIQPLLELDQNRSKLKL 1025
Score = 33.1 bits (72), Expect = 4.5
Identities = 28/132 (21%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
Query: 710 ELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYAD 769
EL LR + E+E +++ L +DE + L E L + +A + E + A+
Sbjct: 280 ELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATE-EDHERTRRLAE 338
Query: 770 LESKAKYESMQANIRNMEDAQRIAELET--EVSEYKLKNEVMATEGELRNNNMDDSDR-V 826
E + + E++ E+ E + K + + T E++++ + +R +
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGL 398
Query: 827 RELQEQVAELKA 838
R+L+E++ LK+
Sbjct: 399 RDLEEEIQMLKS 410
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 48.0 bits (109), Expect = 1e-04
Identities = 106/478 (22%), Positives = 199/478 (41%), Gaps = 55/478 (11%)
Query: 401 DLLSLDMESILKYIQKELPLKAEADQAAFMNL-AYSVKVNP--KKMKKLEKEYTVIKTKE 457
+L LD E+I K +++ L+ EA Q A +L A KVN K KLE++ +++
Sbjct: 127 ELSGLD-ETIAKLTREKKALQ-EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL 184
Query: 458 QGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALR 517
+ + + L + R L+ + + + + E L +V+ +
Sbjct: 185 EQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQ 244
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
+ Q+++ I LE I + ++ E S ++ EEL+ L+
Sbjct: 245 TLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTS 304
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+ E E LRR D A LQ E + LR+ A+ S+ +L
Sbjct: 305 TQIELNK-----------KREAEFLKLRR---DLEEATLQHEAMVATLRKKHAD-SVAEL 349
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
+++ L Q+ L++ K E + D+ ++ + + ++ L+++L
Sbjct: 350 GEQIDNLQRVKQK-LEKEKSEFKLE------IDDLSSSMESVSKSKANLEKICRTLEDQL 402
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQ 757
R + E L EL + L+T+ +L RQ EE +E++ + L R +
Sbjct: 403 SEARGKNEEIQRSLSELTTQKSRLQTEA----GELSRQLEE----KESIVSQLSRSKQAF 454
Query: 758 TRQREFQHKYADLESKAK---YESMQAN------IRNM--EDAQRIAELE-------TEV 799
T+Q E + + E+KAK ++Q++ +R E+ + AEL+ +EV
Sbjct: 455 TQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEV 514
Query: 800 SEYKLKNEVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
++++ K E A + EL + R+++ +EQV + A+ LE K R G E
Sbjct: 515 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVE 572
Score = 46.8 bits (106), Expect = 3e-04
Identities = 70/344 (20%), Positives = 146/344 (42%), Gaps = 18/344 (5%)
Query: 508 ALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELAR 567
ALD +++ ++R N +++Q +A ++I TI E + +E ++ EE
Sbjct: 637 ALD-QLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA 695
Query: 568 CLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLRE 627
L+ I E + E + L+R V +Q L A ++R
Sbjct: 696 ALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRN-YQRTVETMQSALDA-EVRS 753
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
+ LK ++ +L+E + ++Q A +V + T L A G+
Sbjct: 754 RNEAIRLK--KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 811
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
L E+L R E++ELR + + E +++ +L +E +LL
Sbjct: 812 ----DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 867
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAE---LETEVSEY-- 802
+ + ++ L+T + Q + D A+ +A + + DA +AE E + S +
Sbjct: 868 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK-KAITDAAMMAEELKKEQDTSAHLE 926
Query: 803 KLKNEVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLE 844
++K + T +L+ + +D++++ ++ ++Q+ +L+ I LE
Sbjct: 927 RMKKNLEQTVKDLQ-HRLDEAEQLALKGGKKQIQKLETRIRELE 969
Score = 41.9 bits (94), Expect = 0.010
Identities = 54/268 (20%), Positives = 111/268 (41%), Gaps = 5/268 (1%)
Query: 596 ELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+LE+E L++ ++ +A ++ E A + + L L + +++L+ + +
Sbjct: 88 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQE 147
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALT-ELK 712
H+Q + + V+ + T KL + E + L+ +++L R L +LK
Sbjct: 148 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS-LEQEKKLRVDLERNKRKLEGDLK 206
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
+ +++LE Q +L+++D E L+ ++ Q + +E Q + +LE
Sbjct: 207 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 266
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
+ + E + + ELE + V +T+ EL + ++R E+
Sbjct: 267 EIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEE 326
Query: 833 VAELKAEIMRLEAWKSRALGHTELSRAI 860
A L+ E M K A EL I
Sbjct: 327 -ATLQHEAMVATLRKKHADSVAELGEQI 353
Score = 32.3 bits (70), Expect = 7.8
Identities = 56/288 (19%), Positives = 115/288 (39%), Gaps = 17/288 (5%)
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC---LQXXXX 574
R D++++LA+ L+ AE +++LE TE A +EL +Q
Sbjct: 808 RGQEDLKEQLAIVERRANLLQ---AEVEELRATLEQTERARKLAEQELLDSNERVQLLHT 864
Query: 575 XXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLR-EAEANLS 633
E+E+ ++ R A ++A +L+ E + +
Sbjct: 865 QNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAH 924
Query: 634 LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKL 693
L+ +++ + + + Q L E +Q A + + + ++L EG +
Sbjct: 925 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ--IQKLETRIRELEFELEGEQKKNTES 982
Query: 694 DEELMTTRIREVEALTELKELR---LKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
+ L R E + +E R L++ +L ++QV +RQ EEA E +A L
Sbjct: 983 VKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEA---DEQANAHL 1039
Query: 751 QRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETE 798
+ R Q E + + AD+ ++++ ++A R+ ++ + E
Sbjct: 1040 TKFRKAQHELEEAEER-ADI-AESQVNKLRAKTRDFTSSRMVVHESEE 1085
>AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein
protein.
Length = 1177
Score = 48.0 bits (109), Expect = 1e-04
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 28/283 (9%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSEL--------- 644
I+ELE NK+L Q+ + + L+D++ + + +++LR+RV E+
Sbjct: 342 IEELEEINKNL--QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK 399
Query: 645 SES----WQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTT 700
+ES ++ LQE + + ++ + M+ +KL A+ ++ +L L
Sbjct: 400 TESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE 459
Query: 701 RIREVEALTELKELRLKVMELE-TQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + L EL+ ++ +V ELE ++ ++ +L +D+ +L + +R+ ++
Sbjct: 460 KNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKI 519
Query: 760 QREFQHKYADLESKAKYES---MQANIRNMEDAQRIAELETEVSE--YKLKNEVMATEGE 814
++E + K L K E M + +E+++++ +L++E+ E Y L E G+
Sbjct: 520 KQE-ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 578
Query: 815 LRNNNMDDS------DRVRELQEQVAELKAEIMRLEAWKSRAL 851
L++ S D +++ + + E++ EI R + K L
Sbjct: 579 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSEL 621
Score = 40.3 bits (90), Expect = 0.030
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 6/109 (5%)
Query: 737 EEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
+E L E L LQ+ ++ + + +Y LE K + E +AN + Q++ E++
Sbjct: 630 KELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS----QQLEEIK 685
Query: 797 TEVSEYKL--KNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
++++ K K EV++ E ELR+ + + R+L+ +V LK +I L
Sbjct: 686 HQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 734
Score = 39.1 bits (87), Expect = 0.068
Identities = 48/233 (20%), Positives = 107/233 (45%), Gaps = 19/233 (8%)
Query: 629 EANLSLKDLRQRVSELSESWQRHLQEHKQE--------APAAPVQSNVVSDIMATPKKLL 680
+ L L L QR+ EL E ++LQ+ ++E A S++++++ K++L
Sbjct: 330 QLRLKLVGLTQRIEELEEI-NKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 388
Query: 681 RAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELE---TQVQVSTNQLRRQDE 737
EG+ ++ K + + R + E KELRL+V +L+ ++++ +
Sbjct: 389 EM-EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 447
Query: 738 EARLLRENLDAALQRERALQTRQREFQHKYADLE-SKAKYE----SMQANIRNMEDAQRI 792
E L NL+ + L + + +LE S+++ E S++ ++ ++ +
Sbjct: 448 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 507
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
E + K+K E +G L N + +V ++ E++ E ++++L++
Sbjct: 508 LVDERKNMMEKIKQEERKVDG-LNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
>AL136093-3|CAI42825.1| 1285|Homo sapiens myosin VI protein.
Length = 1285
Score = 48.0 bits (109), Expect = 1e-04
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 13/171 (7%)
Query: 690 MLKLDEELMTTRI--REVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
M K+ +MT +E +AL + E L ++ + Q + +LRR EE R+
Sbjct: 882 MAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERK--- 938
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNE 807
+RE + R++E + + LE +AK + + + ED ++ + E E + K E
Sbjct: 939 ---RREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE 995
Query: 808 VMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSR 858
+ L D REL ++A+ +AE++ EA AL + +R
Sbjct: 996 ESQQQAVLEQERRD-----RELALRIAQSEAELISDEAQADLALRRNDGTR 1041
Score = 37.9 bits (84), Expect = 0.16
Identities = 58/228 (25%), Positives = 107/228 (46%), Gaps = 28/228 (12%)
Query: 618 DELIAV-KLREAEANLSLKDLRQRVSELSESWQRHL--QEHKQEAPAAPVQSNVVSDIMA 674
+E+++V K + E N +K+L + L + + QE Q+ A V+S+ ++++
Sbjct: 854 NEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSS--EELLS 911
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+K + E + + ++ EE+ R R E E R + E E ++++ R+
Sbjct: 912 ALQKK-KQQEEEAERLRRIQEEMEKERKRREE-----DEKRRRKEEEERRMKLEMEAKRK 965
Query: 735 QDEEARLLRENLDAALQRE-RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
Q+EE R RE+ + +Q E A RQ+E E + ++ R+ E A RIA
Sbjct: 966 QEEEERKKREDDEKRIQAEVEAQLARQKE--------EESQQQAVLEQERRDRELALRIA 1017
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIM 841
+ E E+ + +E A + LR N D R + EQ+A+ +E +
Sbjct: 1018 QSEAEL----ISDEAQA-DLALRRN---DGTRPKMTPEQMAKEMSEFL 1057
>AL109897-3|CAI19521.1| 1285|Homo sapiens myosin VI protein.
Length = 1285
Score = 48.0 bits (109), Expect = 1e-04
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 13/171 (7%)
Query: 690 MLKLDEELMTTRI--REVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
M K+ +MT +E +AL + E L ++ + Q + +LRR EE R+
Sbjct: 882 MAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERK--- 938
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNE 807
+RE + R++E + + LE +AK + + + ED ++ + E E + K E
Sbjct: 939 ---RREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE 995
Query: 808 VMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSR 858
+ L D REL ++A+ +AE++ EA AL + +R
Sbjct: 996 ESQQQAVLEQERRD-----RELALRIAQSEAELISDEAQADLALRRNDGTR 1041
Score = 37.9 bits (84), Expect = 0.16
Identities = 58/228 (25%), Positives = 107/228 (46%), Gaps = 28/228 (12%)
Query: 618 DELIAV-KLREAEANLSLKDLRQRVSELSESWQRHL--QEHKQEAPAAPVQSNVVSDIMA 674
+E+++V K + E N +K+L + L + + QE Q+ A V+S+ ++++
Sbjct: 854 NEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSS--EELLS 911
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+K + E + + ++ EE+ R R E E R + E E ++++ R+
Sbjct: 912 ALQKK-KQQEEEAERLRRIQEEMEKERKRREE-----DEKRRRKEEEERRMKLEMEAKRK 965
Query: 735 QDEEARLLRENLDAALQRE-RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
Q+EE R RE+ + +Q E A RQ+E E + ++ R+ E A RIA
Sbjct: 966 QEEEERKKREDDEKRIQAEVEAQLARQKE--------EESQQQAVLEQERRDRELALRIA 1017
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIM 841
+ E E+ + +E A + LR N D R + EQ+A+ +E +
Sbjct: 1018 QSEAEL----ISDEAQA-DLALRRN---DGTRPKMTPEQMAKEMSEFL 1057
>AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransferase
9 protein.
Length = 978
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/264 (21%), Positives = 118/264 (44%), Gaps = 21/264 (7%)
Query: 597 LENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHK 656
L+ + + L+++ + N L+D KL + + L + +QR S +E ++ ++ +
Sbjct: 472 LQQQQQMLQQETIRNG--ELEDT--QTKLEKQVSKLEQELQKQRESS-AEKLRKMEEKCE 526
Query: 657 QEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRL 716
A A ++ V ++ T +++ + ++ K+++E+M + +L +
Sbjct: 527 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHFSQLDM 586
Query: 717 KVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKY 776
+ + +T+++ TN ++ ++ L ALQ+ L+T E Q+ + +L+S +
Sbjct: 587 ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLET---ELQNAHGELKSTLR- 642
Query: 777 ESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAEL 836
++ + D + A+L E +Y ++ A ELR M+ D +EL E L
Sbjct: 643 -----QLQELRDVLQKAQLSLE-EKYTTIKDLTA---ELRECKMEIEDEKQELLEMDQAL 693
Query: 837 KAEIMRLEAWKSRALGHTELSRAI 860
K L K RA T L I
Sbjct: 694 KERNWEL---KQRAAQVTHLDMTI 714
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/161 (18%), Positives = 72/161 (44%), Gaps = 4/161 (2%)
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
++M K +L+T + E + + K ELE ++ ++R + E +
Sbjct: 251 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKIC 310
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKN- 806
A ++ + + Q + K + +A+ E + E + + + ++ L++
Sbjct: 311 LAFEKAKKIHLEQHKEMEKQIE-RLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESL 369
Query: 807 EVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
+ + TE GE++ NM + ++ LQ QV+E ++ +L++
Sbjct: 370 DRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDS 410
Score = 40.7 bits (91), Expect = 0.022
Identities = 53/252 (21%), Positives = 113/252 (44%), Gaps = 29/252 (11%)
Query: 596 ELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEH 655
EL +N+ +R + N H + L K ++ K++ +++ L ++ Q+
Sbjct: 287 ELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQH-KEMEKQIERLEAQLEKKDQQF 345
Query: 656 K-QEAPAAPVQSNVV--SDIMATPKKLLRAWEGR-SADMLKLDEELM---------TTRI 702
K QE + +Q +++ + + +LL +G + +K DE L T ++
Sbjct: 346 KEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKV 405
Query: 703 REVEALTEL--KELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQ 760
R++++ E+ +EL L + +LE + QL+++ EE L++ L + +
Sbjct: 406 RQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQN 465
Query: 761 REFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNM 820
QH + + E+ IRN ELE ++ KL+ +V E EL+
Sbjct: 466 VILQHTLQQQQQMLQQET----IRN-------GELED--TQTKLEKQVSKLEQELQKQRE 512
Query: 821 DDSDRVRELQEQ 832
++++R+++E+
Sbjct: 513 SSAEKLRKMEEK 524
Score = 33.5 bits (73), Expect = 3.4
Identities = 63/316 (19%), Positives = 121/316 (38%), Gaps = 22/316 (6%)
Query: 499 RAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQS----SLEGT 554
+ E E+E L QAL+ N +++QR A ++ L+MTI E+ LEGT
Sbjct: 676 KMEIEDEKQELLEMDQALKERNWELKQRAA----QVTHLDMTIREHRGEMEQKIIKLEGT 731
Query: 555 ESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRR--QRVD-- 610
S + +E + ++ E+ K + R QR+
Sbjct: 732 LEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEM 791
Query: 611 NNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVS 670
+V Q++ IA + +EA + L + E ++ L E + + A + +S
Sbjct: 792 ESVMKEQEQYIATQCKEA---IDLGQKLRLTREQVQNSHTELAEARHQQVQAQREIERLS 848
Query: 671 DIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTN 730
+ K+L + + A L EEL +++RE L + +K + E +
Sbjct: 849 SELEDMKQLSKE---KDAHGNHLAEELGASKVREAH-LEARMQAEIKKLSAEVESLKEAY 904
Query: 731 QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQ 790
+ + + + A Q+ Q + Q + A LE + +++ + ++D
Sbjct: 905 HMEMISHQENHAKWKISADSQKSSVQQLNE---QLEKAKLELEEAQDTVSNLHQQVQDRN 961
Query: 791 RIAELETEVSEYKLKN 806
+ E E K +N
Sbjct: 962 EVIEAANEALLTKGEN 977
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 48.0 bits (109), Expect = 1e-04
Identities = 65/274 (23%), Positives = 130/274 (47%), Gaps = 19/274 (6%)
Query: 597 LENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQE 654
LE++ SL+R ++ + ++ E A + + + + L + +S+L++ ++ LQE
Sbjct: 947 LEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKE-KKSLQE 1005
Query: 655 -HKQEAPAAPVQSNVVSDIMATPKKLLRAW---EGRSADMLKLDEELMTTRIREVEALTE 710
H+Q V+ + V+ ++ KL + EG KL +L + R++E +
Sbjct: 1006 AHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAK-RKLEG--D 1062
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADL 770
LK + +M+LE + Q +L++++ E L+ +D Q + +E Q + +L
Sbjct: 1063 LKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEEL 1122
Query: 771 ESKAKYE-SMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSD---RV 826
E + + E +++A I + + ELE E+SE +L+ AT ++ N +++
Sbjct: 1123 EEEIEAEHTLRAKIEK-QRSDLARELE-EISE-RLEEASGATSAQIEMNKKREAEFQKMR 1179
Query: 827 RELQEQVAELKAEIMRLEAWKSRALGHTELSRAI 860
R+L+E A L+ E K +A EL I
Sbjct: 1180 RDLEE--ATLQHEATAATLRKKQADSVAELGEQI 1211
Score = 42.3 bits (95), Expect = 0.007
Identities = 58/276 (21%), Positives = 131/276 (47%), Gaps = 32/276 (11%)
Query: 594 IDELENENKSLRR--QRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
I +L E KSL+ Q+ +++ +D++ + A+ DL + E + +
Sbjct: 993 ISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSL-EQEKKLRAD 1051
Query: 652 LQEHKQEAPA-APVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE 710
L+ K++ + + D+ +++ + + ++ +L + ++ ++ +
Sbjct: 1052 LERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKK 1111
Query: 711 LKELRLKVMELETQVQVSTNQLRRQDEEAR--LLRENLDAALQRERAL----------QT 758
+KEL+ ++ ELE +++ + LR + E+ R L RE + + + E A +
Sbjct: 1112 IKELQARIEELEEEIEAE-HTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKK 1170
Query: 759 RQREFQHKYADL-ESKAKYESMQANIR------------NMEDAQRIAE-LETEVSEYKL 804
R+ EFQ DL E+ ++E+ A +R +++ QR+ + LE E SE K+
Sbjct: 1171 REAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKM 1230
Query: 805 KNEVMATEGELRNNNMDDSDRV-RELQEQVAELKAE 839
+ + MA+ E + + + +R R +++Q +E+KA+
Sbjct: 1231 EIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAK 1266
Score = 41.1 bits (92), Expect = 0.017
Identities = 59/277 (21%), Positives = 120/277 (43%), Gaps = 30/277 (10%)
Query: 594 IDELENENKSLRRQR--VDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRH 651
ID+LE + +++ +N V +L +E+ A++ ++ K L++ + + Q
Sbjct: 958 IDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQ-- 1015
Query: 652 LQEHKQEA-----PAAPVQSNVVSDIMATPKKLL----RAWEGRSADMLKLDEELMTTRI 702
++E K Q++ + + KKL RA D+ E +M
Sbjct: 1016 VEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEN 1075
Query: 703 REVEALTELKELRLKVMELETQV---QVSTNQLRRQDEEARLLRENLDAALQRERALQTR 759
+ + +LK+ ++ +L+ ++ QV + Q +++ +E + E L+ ++ E L+ +
Sbjct: 1076 EKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAK 1135
Query: 760 --------QREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMAT 811
RE + LE + S Q + +A+ ++ ++ E L++E AT
Sbjct: 1136 IEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAE-FQKMRRDLEEATLQHE--AT 1192
Query: 812 EGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKS 848
LR +D V EL EQ+ L+ +LE KS
Sbjct: 1193 AATLRKKQ---ADSVAELGEQIDNLQRVKQKLEKEKS 1226
Score = 40.3 bits (90), Expect = 0.030
Identities = 67/369 (18%), Positives = 147/369 (39%), Gaps = 19/369 (5%)
Query: 444 KKLEKEYTVIKTKEQGDIAV----LRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDR 499
KKL + K K +GD+ + + L E + +++++ QV
Sbjct: 1046 KKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHS 1105
Query: 500 AEGEEETFALDREVQALRRANVDMQQRLAVALDEIRS-LEMTIAENNSRQSSLEGTESAS 558
+ +++ L ++ L ++ + L +++ RS L + E + R G SA
Sbjct: 1106 LQFQKKIKELQARIEELEE-EIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQ 1164
Query: 559 ---GQKHE-ELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVA 614
+K E E + + + EL + +L+R +
Sbjct: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVK-----Q 1219
Query: 615 HLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMA 674
L+ E +K+ + +++ L + S + + R +++ E A Q + +
Sbjct: 1220 KLEKEKSELKMEIDDMASNIEALSKSKSNIERTC-RTVEDQFSEIKAKDEQQTQLIHDLN 1278
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTE-LKELRLKVMELETQVQ-VSTNQL 732
K L+ G + ++ E L++ + +ALT+ L+EL+ + ME ET+ + + L
Sbjct: 1279 MQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK-RQMEEETKAKNAMAHAL 1337
Query: 733 RRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
+ + LLRE + + + LQ + + A ++K + +++Q E +++
Sbjct: 1338 QSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKL 1397
Query: 793 AELETEVSE 801
A+ E E
Sbjct: 1398 AQRLQEAEE 1406
Score = 40.3 bits (90), Expect = 0.030
Identities = 60/282 (21%), Positives = 125/282 (44%), Gaps = 36/282 (12%)
Query: 594 IDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
I+ + ++ R D A LQ E A LR+ +A+ S+ +L +++ L Q+ L+
Sbjct: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD-SVAELGEQIDNLQRVKQK-LE 1222
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKE 713
+ K E + D+ + + L ++ ++++ + ++ + + +
Sbjct: 1223 KEKSELKME------IDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHD 1276
Query: 714 LRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESK 773
L ++ L+TQ +L + EE +E+L + L + + T+Q E + + E+K
Sbjct: 1277 LNMQKARLQTQ----NGELSHRVEE----KESLISQLTKSKQALTQQLEELKRQMEEETK 1328
Query: 774 AKY---ESMQAN------IRNM--EDAQRIAELE-------TEVSEYKLKNEVMATE--G 813
AK ++Q++ +R E+ + AEL+ +EV+++K K E A +
Sbjct: 1329 AKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTE 1388
Query: 814 ELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
EL + R++E +E+ ++ LE K R G E
Sbjct: 1389 ELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVE 1430
Score = 33.9 bits (74), Expect = 2.6
Identities = 36/159 (22%), Positives = 66/159 (41%), Gaps = 8/159 (5%)
Query: 689 DMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDA 748
D + EEL + R E ++ L + +L+ QVQ T L +E L ++
Sbjct: 859 DFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIL 918
Query: 749 ALQRERALQTRQREFQHKYADLESKA-----KYESMQANIRNMEDAQRIAELETEVSEYK 803
+ + L R E + ++L +K K S++ +I ++E E E +E K
Sbjct: 919 LEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENK 978
Query: 804 LKN---EVMATEGELRNNNMDDSDRVRELQEQVAELKAE 839
+KN E+ A E + + Q+ + +L+ E
Sbjct: 979 VKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE 1017
>AB002387-1|BAA20843.2| 1296|Homo sapiens KIAA0389 protein.
Length = 1296
Score = 48.0 bits (109), Expect = 1e-04
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 13/171 (7%)
Query: 690 MLKLDEELMTTRI--REVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
M K+ +MT +E +AL + E L ++ + Q + +LRR EE R+
Sbjct: 893 MAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERK--- 949
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNE 807
+RE + R++E + + LE +AK + + + ED ++ + E E + K E
Sbjct: 950 ---RREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE 1006
Query: 808 VMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSR 858
+ L D REL ++A+ +AE++ EA AL + +R
Sbjct: 1007 ESQQQAVLEQERRD-----RELALRIAQSEAELISDEAQADLALRRNDGTR 1052
Score = 37.9 bits (84), Expect = 0.16
Identities = 58/228 (25%), Positives = 107/228 (46%), Gaps = 28/228 (12%)
Query: 618 DELIAV-KLREAEANLSLKDLRQRVSELSESWQRHL--QEHKQEAPAAPVQSNVVSDIMA 674
+E+++V K + E N +K+L + L + + QE Q+ A V+S+ ++++
Sbjct: 865 NEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSS--EELLS 922
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+K + E + + ++ EE+ R R E E R + E E ++++ R+
Sbjct: 923 ALQKK-KQQEEEAERLRRIQEEMEKERKRREE-----DEKRRRKEEEERRMKLEMEAKRK 976
Query: 735 QDEEARLLRENLDAALQRE-RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
Q+EE R RE+ + +Q E A RQ+E E + ++ R+ E A RIA
Sbjct: 977 QEEEERKKREDDEKRIQAEVEAQLARQKE--------EESQQQAVLEQERRDRELALRIA 1028
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIM 841
+ E E+ + +E A + LR N D R + EQ+A+ +E +
Sbjct: 1029 QSEAEL----ISDEAQA-DLALRRN---DGTRPKMTPEQMAKEMSEFL 1068
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 47.6 bits (108), Expect = 2e-04
Identities = 106/478 (22%), Positives = 199/478 (41%), Gaps = 55/478 (11%)
Query: 401 DLLSLDMESILKYIQKELPLKAEADQAAFMNL-AYSVKVNP--KKMKKLEKEYTVIKTKE 457
+L LD E+I K +++ L+ EA Q A +L A KVN K KLE++ +++
Sbjct: 982 ELSGLD-ETIAKLTREKKALQ-EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL 1039
Query: 458 QGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALR 517
+ + + L + R L+ + + + + E L +V+ +
Sbjct: 1040 EQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQ 1099
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
+ Q+++ I LE I + ++ E S ++ EEL+ L+
Sbjct: 1100 TLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTS 1159
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+ E E LRR D A LQ E + LR+ A+ S+ +L
Sbjct: 1160 TQIELNK-----------KREAEFLKLRR---DLEEATLQHEAMVATLRKKHAD-SVAEL 1204
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
+++ L Q+ L++ K E + D+ ++ + + ++ L+++L
Sbjct: 1205 GEQIDNLQRVKQK-LEKEKSEFKLE------IDDLSSSMESVSKSKANLEKICRTLEDQL 1257
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQ 757
R + E L EL + L+T+ +L RQ EE +E++ + L R +
Sbjct: 1258 SEARGKNEEIQRSLSELTTQKSRLQTEA----GELSRQLEE----KESIVSQLSRSKQAF 1309
Query: 758 TRQREFQHKYADLESKAK---YESMQAN------IRNM--EDAQRIAELE-------TEV 799
T+Q E + + E+KAK ++Q++ +R E+ + AEL+ +EV
Sbjct: 1310 TQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEV 1369
Query: 800 SEYKLKNEVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
++++ K E A + EL + R+++ +EQV + A+ LE K R G E
Sbjct: 1370 AQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVE 1427
Score = 46.8 bits (106), Expect = 3e-04
Identities = 70/344 (20%), Positives = 146/344 (42%), Gaps = 18/344 (5%)
Query: 508 ALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELAR 567
ALD +++ ++R N +++Q +A ++I TI E + +E ++ EE
Sbjct: 1492 ALD-QLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA 1550
Query: 568 CLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLRE 627
L+ I E + E + L+R V +Q L A ++R
Sbjct: 1551 ALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRN-YQRTVETMQSALDA-EVRS 1608
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
+ LK ++ +L+E + ++Q A +V + T L A G+
Sbjct: 1609 RNEAIRLK--KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 1666
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
L E+L R E++ELR + + E +++ +L +E +LL
Sbjct: 1667 ----DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 1722
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAE---LETEVSEY-- 802
+ + ++ L+T + Q + D A+ +A + + DA +AE E + S +
Sbjct: 1723 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK-KAITDAAMMAEELKKEQDTSAHLE 1781
Query: 803 KLKNEVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLE 844
++K + T +L+ + +D++++ ++ ++Q+ +L+ I LE
Sbjct: 1782 RMKKNLEQTVKDLQ-HRLDEAEQLALKGGKKQIQKLETRIRELE 1824
Score = 41.9 bits (94), Expect = 0.010
Identities = 54/268 (20%), Positives = 111/268 (41%), Gaps = 5/268 (1%)
Query: 596 ELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+LE+E L++ ++ +A ++ E A + + L L + +++L+ + +
Sbjct: 943 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQE 1002
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALT-ELK 712
H+Q + + V+ + T KL + E + L+ +++L R L +LK
Sbjct: 1003 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS-LEQEKKLRVDLERNKRKLEGDLK 1061
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
+ +++LE Q +L+++D E L+ ++ Q + +E Q + +LE
Sbjct: 1062 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 1121
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
+ + E + + ELE + V +T+ EL + ++R E+
Sbjct: 1122 EIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEE 1181
Query: 833 VAELKAEIMRLEAWKSRALGHTELSRAI 860
A L+ E M K A EL I
Sbjct: 1182 -ATLQHEAMVATLRKKHADSVAELGEQI 1208
Score = 32.3 bits (70), Expect = 7.8
Identities = 56/288 (19%), Positives = 115/288 (39%), Gaps = 17/288 (5%)
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC---LQXXXX 574
R D++++LA+ L+ AE +++LE TE A +EL +Q
Sbjct: 1663 RGQEDLKEQLAIVERRANLLQ---AEVEELRATLEQTERARKLAEQELLDSNERVQLLHT 1719
Query: 575 XXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLR-EAEANLS 633
E+E+ ++ R A ++A +L+ E + +
Sbjct: 1720 QNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1779
Query: 634 LKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKL 693
L+ +++ + + + Q L E +Q A + + + ++L EG +
Sbjct: 1780 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ--IQKLETRIRELEFELEGEQKKNTES 1837
Query: 694 DEELMTTRIREVEALTELKELR---LKVMELETQVQVSTNQLRRQDEEARLLRENLDAAL 750
+ L R E + +E R L++ +L ++QV +RQ EEA E +A L
Sbjct: 1838 VKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEA---DEQANAHL 1894
Query: 751 QRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETE 798
+ R Q E + + AD+ ++++ ++A R+ ++ + E
Sbjct: 1895 TKFRKAQHELEEAEER-ADI-AESQVNKLRAKTRDFTSSRMVVHESEE 1940
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 47.6 bits (108), Expect = 2e-04
Identities = 106/478 (22%), Positives = 199/478 (41%), Gaps = 55/478 (11%)
Query: 401 DLLSLDMESILKYIQKELPLKAEADQAAFMNL-AYSVKVNP--KKMKKLEKEYTVIKTKE 457
+L LD E+I K +++ L+ EA Q A +L A KVN K KLE++ +++
Sbjct: 209 ELSGLD-ETIAKLTREKKALQ-EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL 266
Query: 458 QGDIAVLRCLRQENRLLKQRVXXXXXXXXXXXXXXVRGQVDRAEGEEETFALDREVQALR 517
+ + + L + R L+ + + + + E L +V+ +
Sbjct: 267 EQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQ 326
Query: 518 RANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARCLQXXXXXXX 577
+ Q+++ I LE I + ++ E S ++ EEL+ L+
Sbjct: 327 TLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTS 386
Query: 578 XXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSLKDL 637
+ E E LRR D A LQ E + LR+ A+ S+ +L
Sbjct: 387 TQIELNK-----------KREAEFLKLRR---DLEEATLQHEAMVATLRKKHAD-SVAEL 431
Query: 638 RQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEEL 697
+++ L Q+ L++ K E + D+ ++ + + ++ L+++L
Sbjct: 432 GEQIDNLQRVKQK-LEKEKSEFKLE------IDDLSSSMESVSKSKANLEKICRTLEDQL 484
Query: 698 MTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQ 757
R + E L EL + L+T+ +L RQ EE +E++ + L R +
Sbjct: 485 SEARGKNEEIQRSLSELTTQKSRLQTEA----GELSRQLEE----KESIVSQLSRSKQAF 536
Query: 758 TRQREFQHKYADLESKAK---YESMQAN------IRNM--EDAQRIAELE-------TEV 799
T+Q E + + E+KAK ++Q++ +R E+ + AEL+ +EV
Sbjct: 537 TQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEV 596
Query: 800 SEYKLKNEVMATE--GELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTE 855
++++ K E A + EL + R+++ +EQV + A+ LE K R G E
Sbjct: 597 AQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVE 654
Score = 44.4 bits (100), Expect = 0.002
Identities = 69/344 (20%), Positives = 146/344 (42%), Gaps = 18/344 (5%)
Query: 508 ALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELAR 567
ALD +++ ++R N +++Q +A ++I TI E + +E ++ EE
Sbjct: 719 ALD-QLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA 777
Query: 568 CLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNNVAHLQDELIAVKLRE 627
L+ I E + E + L+R V +Q L A ++R
Sbjct: 778 ALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRN-YQRTVETMQSALDA-EVRS 835
Query: 628 AEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRS 687
+ LK ++ +L+E + ++Q A +V + T L A + +
Sbjct: 836 RNEAIRLK--KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQE 893
Query: 688 ADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
L E+L R E++ELR + + E +++ +L +E +LL
Sbjct: 894 ----DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 949
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAE---LETEVSEY-- 802
+ + ++ L+T + Q + D A+ +A + + DA +AE E + S +
Sbjct: 950 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK-KAITDAAMMAEELKKEQDTSAHLE 1008
Query: 803 KLKNEVMATEGELRNNNMDDSDR--VRELQEQVAELKAEIMRLE 844
++K + T +L+ + +D++++ ++ ++Q+ +L+ I LE
Sbjct: 1009 RMKKNLEQTVKDLQ-HRLDEAEQLALKGGKKQIQKLETRIRELE 1051
Score = 41.9 bits (94), Expect = 0.010
Identities = 54/268 (20%), Positives = 111/268 (41%), Gaps = 5/268 (1%)
Query: 596 ELENENKSLRRQ--RVDNNVAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQ 653
+LE+E L++ ++ +A ++ E A + + L L + +++L+ + +
Sbjct: 170 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQE 229
Query: 654 EHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALT-ELK 712
H+Q + + V+ + T KL + E + L+ +++L R L +LK
Sbjct: 230 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS-LEQEKKLRVDLERNKRKLEGDLK 288
Query: 713 ELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLES 772
+ +++LE Q +L+++D E L+ ++ Q + +E Q + +LE
Sbjct: 289 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 348
Query: 773 KAKYESMQANIRNMEDAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQ 832
+ + E + + ELE + V +T+ EL + ++R E+
Sbjct: 349 EIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEE 408
Query: 833 VAELKAEIMRLEAWKSRALGHTELSRAI 860
A L+ E M K A EL I
Sbjct: 409 -ATLQHEAMVATLRKKHADSVAELGEQI 435
>U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein.
Length = 3321
Score = 47.6 bits (108), Expect = 2e-04
Identities = 80/358 (22%), Positives = 134/358 (37%), Gaps = 28/358 (7%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC 568
+ +EV LR + L AL E+ S + + + QS LE + Q+ + A+
Sbjct: 2619 VQQEVLQLRSMLSSKENELKAALQELESEQ---GKGRALQSQLEEEQLRHLQRESQSAKA 2675
Query: 569 LQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLR--RQRVD-------NNVAHLQDE 619
L+ +N K LR R + + ++ LQ +
Sbjct: 2676 LEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKD 2735
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
L A K R E + +L+ R +LS+ Q +A A +Q + + + L
Sbjct: 2736 LAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQK--LKEEKSRVVDL 2793
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEALTELKE----LRLKVMELETQVQVSTNQLRRQ 735
E L ++L + EAL KE L+ V L TQ + L R+
Sbjct: 2794 QAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLERE 2853
Query: 736 DEEARLLRENLDAAL-----QRERALQTRQREFQHKYADLESKAKYESMQANIRNME--- 787
E+ L+ L+ + Q R R E + A E K++ + +R +E
Sbjct: 2854 REKPAWLQAELEQSHPRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQR 2913
Query: 788 --DAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
D +I +L+ V + + K+EV + L + L+EQ EL+A RL
Sbjct: 2914 QRDLHKIKQLQQTVRDLESKDEVPGSRLHLGSARRAAGSDADHLREQQRELEAMRQRL 2971
Score = 37.5 bits (83), Expect = 0.21
Identities = 40/205 (19%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
Query: 645 SESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIRE 704
+E + +++H++ +S +++ K EG + L E L E
Sbjct: 1288 NEETAQVVRKHQELLECLTEESAAKAELALELHKTQGTLEGFKVETADLKEVLAGKEDSE 1347
Query: 705 VEALTELKELRLKVMEL---ETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ EL+ LR ++ + + ++ +L + E E +AAL++E T+++
Sbjct: 1348 HRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALRKEVEDLTKEQ 1407
Query: 762 EFQHKYADLESKAKYESMQANIRNMED--AQRIAELETEVSEYKLKNEVMATEGELRNNN 819
K A+ + A M+ +E+ +Q + + L+ +V + + LRN
Sbjct: 1408 SETRKQAEKDRSALLSQMKILESELEEQLSQHRGCAKQAEAVTALEQQVASLDKHLRNQR 1467
Query: 820 MDDSDRVRELQEQVAELKAEIMRLE 844
++ E + + E + EI RLE
Sbjct: 1468 QFMDEQAAEREHEREEFQQEIQRLE 1492
Score = 36.7 bits (81), Expect = 0.36
Identities = 37/178 (20%), Positives = 79/178 (44%), Gaps = 11/178 (6%)
Query: 677 KKLLRAWEGRSADMLK-LDEELMTTRIREVEALT-----ELKELRLKVMELETQVQVSTN 730
K L WE L+ L +EL E+E L EL E R ++ ++ +
Sbjct: 344 KTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAER 403
Query: 731 QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNM--ED 788
LR + + E L LQ E EF+ K ++ E + + E++QA+ ++ +
Sbjct: 404 ALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKAQS 463
Query: 789 AQRIAELETEVSEYKLKNEVMATEGE---LRNNNMDDSDRVRELQEQVAELKAEIMRL 843
+ I L +++ + + ++ E R + ++D +++++ ++ E + E +R+
Sbjct: 464 QEEIRRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRI 521
Score = 36.3 bits (80), Expect = 0.48
Identities = 44/169 (26%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 694 DEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRE 753
D EL ++E AL +L R + LE + +++ QD +LL+E Q++
Sbjct: 848 DGELAALHVKEDCAL-QLMLARSRF--LEERKEIAEKFSAEQDAFLQLLQERH----QQQ 900
Query: 754 RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEY--KLKNEVMAT 811
T + E +H+ A E A ES Q + A R+AEL+T+ + L+ ++T
Sbjct: 901 LLSVTAELEARHQAALGELTASLESKQGALL----AARVAELQTKHAADLGALETRHLST 956
Query: 812 EGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSRAI 860
L + + + +RE Q EL + WK +L T L++ +
Sbjct: 957 LDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLHQTILTQEL 1005
Score = 35.9 bits (79), Expect = 0.64
Identities = 55/230 (23%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Query: 622 AVKLREAEA-NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLL 680
AV E EA LSL ++ EL+ Q +LQ+ K+ A +++ A LL
Sbjct: 241 AVHGLELEALRLSLSNMHTAQLELT---QANLQKEKETALTE--LREMLNSRRAQELALL 295
Query: 681 RAWEGRSADMLKLDE--ELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
++ + ++L+ E +R + ELKE +L+ E+E Q+ + E
Sbjct: 296 QSRQQHELELLREQHAREKEEVVLRCGQEAAELKE-KLQ-SEMEKNAQIVKTLKEDWESE 353
Query: 739 ARLLRENL--DAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
L ENL + + + + ++ Q +FQ + A E +A+ E + + E A R E
Sbjct: 354 KDLCLENLRKELSAKHQSEMEDLQNQFQKELA--EQRAELEKIFQDKNQAERALRNLESH 411
Query: 797 TEVSEYKLKNEVMATEGE-LRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
+ + KL+ ++ + G L + + +E Q ++ L+A L+A
Sbjct: 412 HQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKA 461
>L16782-1|AAC37542.1| 566|Homo sapiens putative M phase
phosphoprotein (MPP1 protein.
Length = 566
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/262 (24%), Positives = 119/262 (45%), Gaps = 28/262 (10%)
Query: 595 DELENENKSLRRQRVDNNVAHLQDELIAVKLREAEANLSL----KDLRQR-VSELSESWQ 649
++L + K +++++ + +V +D+L+ +K+ E E + D++QR + +L E
Sbjct: 36 EKLTDAKKQIKQEQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLN 95
Query: 650 RH-LQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEAL 708
++E Q+ A NV I+ + L E + ++++ ++ EVE L
Sbjct: 96 NQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQ----DQVLEAKLEEVERL 151
Query: 709 -TELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQREFQHKY 767
TEL++ + K +LET+ NQ R ++E EN L + LQ +E + KY
Sbjct: 152 ATELEKWKEKCNDLETK----NNQ--RSNKE----HENNTDVLGKLTNLQDELQESEQKY 201
Query: 768 ADLESKAKYESMQANIRNMEDAQRIAELE----TEVSE--YKLKNEVMATEGELRNNNMD 821
+ +SK E I ++A+ I E E E +K +NE+ +L + D
Sbjct: 202 -NADSKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSD 260
Query: 822 DSDRVRELQEQVAELKAEIMRL 843
E + VA L+ ++ L
Sbjct: 261 LQKWREERDQLVAALEIQLKAL 282
>BC028366-1|AAH28366.1| 698|Homo sapiens testis specific, 10
protein.
Length = 698
Score = 47.6 bits (108), Expect = 2e-04
Identities = 73/348 (20%), Positives = 142/348 (40%), Gaps = 49/348 (14%)
Query: 493 VRGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
+R Q+D E A +R++ L N ++Q++ A A E ++L + + ++ + ++
Sbjct: 329 MRRQLDETNDELAQIARERDI--LAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIK 386
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+ + +L L+ ++ EN R+ DNN
Sbjct: 387 QKVQDTNLEVNKLKNILKSEESENRQMMEQLRKAN-------EDAENWENKARQSEADNN 439
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
L ELI EAE N L+++V L+ ++HL + + S I
Sbjct: 440 TLKL--ELITA---EAEGNR----LKEKVDSLNREVEQHLNAER----------SYKSQI 480
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
K ++ K++EEL + +V AL +L R ++L++ ++ QL
Sbjct: 481 STLHKSVV-----------KMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELLNRQL 529
Query: 733 RRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
+D+E + LD+A L+++ + +LE+ + AN R+ E +I
Sbjct: 530 VAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEA-----LLVAN-RDKEYQSQI 583
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
A E E LK + E ++ + D V + + V +L+A++
Sbjct: 584 ALQEKESEIQLLKEHLCLAENKMAIQSRD----VAQFRNVVTQLEADL 627
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 22/196 (11%)
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
K E A +Q NV + + K+ +E ++ +L E+M + + ++ T LR
Sbjct: 42 KYERHLAEIQGNV-KVLKSERDKIFLLYEQAQEEITRLRREMMKS-CKSPKSTTAHAILR 99
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENL----DAALQRERALQTRQREFQ---HKYA 768
+ET+ V+ LRR E LRE L + A + L+ R E + H
Sbjct: 100 ----RVETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLD 155
Query: 769 D--LESKAKYESMQANIRNMED-----AQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
D +E + M+ I +E A++ + E+E+ K +N + E N D
Sbjct: 156 DERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYE--NTEKD 213
Query: 822 DSDRVRELQEQVAELK 837
SD R L ++ EL+
Sbjct: 214 LSDTQRHLAKKKYELQ 229
>AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein.
Length = 3336
Score = 47.6 bits (108), Expect = 2e-04
Identities = 80/358 (22%), Positives = 134/358 (37%), Gaps = 28/358 (7%)
Query: 509 LDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLEGTESASGQKHEELARC 568
+ +EV LR + L AL E+ S + + + QS LE + Q+ + A+
Sbjct: 2630 VQQEVLQLRSMLSSKENELKAALQELESEQ---GKGRALQSQLEEEQLRHLQRESQSAKA 2686
Query: 569 LQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLR--RQRVD-------NNVAHLQDE 619
L+ +N K LR R + + ++ LQ +
Sbjct: 2687 LEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKD 2746
Query: 620 LIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKL 679
L A K R E + +L+ R +LS+ Q +A A +Q + + + L
Sbjct: 2747 LAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQK--LKEEKSRVVDL 2804
Query: 680 LRAWEGRSADMLKLDEELMTTRIREVEALTELKE----LRLKVMELETQVQVSTNQLRRQ 735
E L ++L + EAL KE L+ V L TQ + L R+
Sbjct: 2805 QAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLERE 2864
Query: 736 DEEARLLRENLDAAL-----QRERALQTRQREFQHKYADLESKAKYESMQANIRNME--- 787
E+ L+ L+ + Q R R E + A E K++ + +R +E
Sbjct: 2865 REKPAWLQAELEQSHPRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQR 2924
Query: 788 --DAQRIAELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRL 843
D +I +L+ V + + K+EV + L + L+EQ EL+A RL
Sbjct: 2925 QRDLHKIKQLQQTVRDLESKDEVPGSRLHLGSARRAAGSDADHLREQQRELEAMRQRL 2982
Score = 37.5 bits (83), Expect = 0.21
Identities = 40/205 (19%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
Query: 645 SESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIRE 704
+E + +++H++ +S +++ K EG + L E L E
Sbjct: 1299 NEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVETADLKEVLAGKEDSE 1358
Query: 705 VEALTELKELRLKVMEL---ETQVQVSTNQLRRQDEEARLLRENLDAALQRERALQTRQR 761
+ EL+ LR ++ + + ++ +L + E E +AAL++E T+++
Sbjct: 1359 HRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALRKEVEDLTKEQ 1418
Query: 762 EFQHKYADLESKAKYESMQANIRNMED--AQRIAELETEVSEYKLKNEVMATEGELRNNN 819
K A+ + A M+ +E+ +Q + + L+ +V + + LRN
Sbjct: 1419 SETRKQAEKDRSALLSQMKILESELEEQLSQHRGCAKQAEAVTALEQQVASLDKHLRNQR 1478
Query: 820 MDDSDRVRELQEQVAELKAEIMRLE 844
++ E + + E + EI RLE
Sbjct: 1479 QFMDEQAAEREHEREEFQQEIQRLE 1503
Score = 36.7 bits (81), Expect = 0.36
Identities = 37/178 (20%), Positives = 79/178 (44%), Gaps = 11/178 (6%)
Query: 677 KKLLRAWEGRSADMLK-LDEELMTTRIREVEALT-----ELKELRLKVMELETQVQVSTN 730
K L WE L+ L +EL E+E L EL E R ++ ++ +
Sbjct: 344 KTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAER 403
Query: 731 QLRRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNM--ED 788
LR + + E L LQ E EF+ K ++ E + + E++QA+ ++ +
Sbjct: 404 ALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKAQS 463
Query: 789 AQRIAELETEVSEYKLKNEVMATEGE---LRNNNMDDSDRVRELQEQVAELKAEIMRL 843
+ I L +++ + + ++ E R + ++D +++++ ++ E + E +R+
Sbjct: 464 QEEIRRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRI 521
Score = 35.9 bits (79), Expect = 0.64
Identities = 55/230 (23%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Query: 622 AVKLREAEA-NLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDIMATPKKLL 680
AV E EA LSL ++ EL+ Q +LQ+ K+ A +++ A LL
Sbjct: 241 AVHGLELEALRLSLSNMHTAQLELT---QANLQKEKETALTE--LREMLNSRRAQELALL 295
Query: 681 RAWEGRSADMLKLDE--ELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRRQDEE 738
++ + ++L+ E +R + ELKE +L+ E+E Q+ + E
Sbjct: 296 QSRQQHELELLREQHAREKEEVVLRCGQEAAELKE-KLQ-SEMEKNAQIVKTLKEDWESE 353
Query: 739 ARLLRENL--DAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELE 796
L ENL + + + + ++ Q +FQ + A E +A+ E + + E A R E
Sbjct: 354 KDLCLENLRKELSAKHQSEMEDLQNQFQKELA--EQRAELEKIFQDKNQAERALRNLESH 411
Query: 797 TEVSEYKLKNEVMATEGE-LRNNNMDDSDRVRELQEQVAELKAEIMRLEA 845
+ + KL+ ++ + G L + + +E Q ++ L+A L+A
Sbjct: 412 HQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKA 461
Score = 33.1 bits (72), Expect = 4.5
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 735 QDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAE 794
Q++ AR L + L Q++ T + E +H+ A E A ES Q + A R+AE
Sbjct: 894 QEQHAREL-QLLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALL----AARVAE 948
Query: 795 LETEVSEY--KLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALG 852
L+T+ + L+ +++ L + + + +RE Q EL + WK +L
Sbjct: 949 LQTKHAADLGALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLH 1008
Query: 853 HTELSRAI 860
T L++ +
Sbjct: 1009 QTILTQEL 1016
>AF254756-1|AAK13079.1| 698|Homo sapiens predicted testis protein
protein.
Length = 698
Score = 47.6 bits (108), Expect = 2e-04
Identities = 73/348 (20%), Positives = 142/348 (40%), Gaps = 49/348 (14%)
Query: 493 VRGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
+R Q+D E A +R++ L N ++Q++ A A E ++L + + ++ + ++
Sbjct: 329 MRRQLDETNDELAQIARERDI--LAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIK 386
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+ + +L L+ ++ EN R+ DNN
Sbjct: 387 QKVQDTNLEVNKLKNILKSEESENRQMMEQLRKAN-------EDAENWENKARQSEADNN 439
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
L ELI EAE N L+++V L+ ++HL + + S I
Sbjct: 440 TLKL--ELITA---EAEGNR----LKEKVDSLNREVEQHLNAER----------SYKSQI 480
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
K ++ K++EEL + +V AL +L R ++L++ ++ QL
Sbjct: 481 STLHKSVV-----------KMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELLNRQL 529
Query: 733 RRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
+D+E + LD+A L+++ + +LE+ + AN R+ E +I
Sbjct: 530 VAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEA-----LLVAN-RDKEYQSQI 583
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
A E E LK + E ++ + D V + + V +L+A++
Sbjct: 584 ALQEKESEIQLLKEHLCLAENKMAIQSRD----VAQFRNVVTQLEADL 627
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 22/196 (11%)
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
K E A +Q NV + + K+ +E ++ +L E+M + + ++ T LR
Sbjct: 42 KYERHLAEIQGNV-KVLKSERDKIFLLYEQAQEEITRLRREMMKS-CKSPKSTTAHAILR 99
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENL----DAALQRERALQTRQREFQ---HKYA 768
+ET+ V+ LRR E LRE L + A + L+ R E + H
Sbjct: 100 ----RVETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLD 155
Query: 769 D--LESKAKYESMQANIRNMED-----AQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
D +E + M+ I +E A++ + E+E+ K +N + E N D
Sbjct: 156 DERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYE--NTEKD 213
Query: 822 DSDRVRELQEQVAELK 837
SD R L ++ EL+
Sbjct: 214 LSDTQRHLAKKKYELQ 229
>AF229111-1|AAK00229.1| 1285|Homo sapiens myosin VI protein.
Length = 1285
Score = 47.6 bits (108), Expect = 2e-04
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 13/171 (7%)
Query: 690 MLKLDEELMTTRI--REVEALTELKELRLKVMELETQVQVSTNQLRRQDEEARLLRENLD 747
M K+ +MT +E +AL + E L ++ + Q + +LRR EE R+
Sbjct: 882 MAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERK--- 938
Query: 748 AALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIAELETEVSEYKLKNE 807
+RE + R++E + + LE +AK + + + ED ++ + E E + K E
Sbjct: 939 ---RREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKXREDDEKRIQAEVEAQLARQKEE 995
Query: 808 VMATEGELRNNNMDDSDRVRELQEQVAELKAEIMRLEAWKSRALGHTELSR 858
+ L D REL ++A+ +AE++ EA AL + +R
Sbjct: 996 ESQQQAVLEQERRD-----RELALRIAQSEAELISDEAQADLALRRNDGTR 1041
Score = 38.3 bits (85), Expect = 0.12
Identities = 58/228 (25%), Positives = 107/228 (46%), Gaps = 28/228 (12%)
Query: 618 DELIAV-KLREAEANLSLKDLRQRVSELSESWQRHL--QEHKQEAPAAPVQSNVVSDIMA 674
+E+++V K + E N +K+L + L + + QE Q+ A V+S+ ++++
Sbjct: 854 NEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSS--EELLS 911
Query: 675 TPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQLRR 734
+K + E + + ++ EE+ R R E E R + E E ++++ R+
Sbjct: 912 ALQKK-KQQEEEAERLRRIQEEMEKERKRREE-----DEKRRRKEEEERRMKLEMEAKRK 965
Query: 735 QDEEARLLRENLDAALQRE-RALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRIA 793
Q+EE R RE+ + +Q E A RQ+E E + ++ R+ E A RIA
Sbjct: 966 QEEEERKXREDDEKRIQAEVEAQLARQKE--------EESQQQAVLEQERRDRELALRIA 1017
Query: 794 ELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEIM 841
+ E E+ + +E A + LR N D R + EQ+A+ +E +
Sbjct: 1018 QSEAEL----ISDEAQA-DLALRRN---DGTRPKMTPEQMAKEMSEFL 1057
>AC019097-1|AAY14820.1| 698|Homo sapiens unknown protein.
Length = 698
Score = 47.6 bits (108), Expect = 2e-04
Identities = 73/348 (20%), Positives = 142/348 (40%), Gaps = 49/348 (14%)
Query: 493 VRGQVDRAEGEEETFALDREVQALRRANVDMQQRLAVALDEIRSLEMTIAENNSRQSSLE 552
+R Q+D E A +R++ L N ++Q++ A A E ++L + + ++ + ++
Sbjct: 329 MRRQLDETNDELAQIARERDI--LAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIK 386
Query: 553 GTESASGQKHEELARCLQXXXXXXXXXXXXXXXXXXXXXXXIDELENENKSLRRQRVDNN 612
+ + +L L+ ++ EN R+ DNN
Sbjct: 387 QKVQDTNLEVNKLKNILKSEESENRQMMEQLRKAN-------EDAENWENKARQSEADNN 439
Query: 613 VAHLQDELIAVKLREAEANLSLKDLRQRVSELSESWQRHLQEHKQEAPAAPVQSNVVSDI 672
L ELI EAE N L+++V L+ ++HL + + S I
Sbjct: 440 TLKL--ELITA---EAEGNR----LKEKVDSLNREVEQHLNAER----------SYKSQI 480
Query: 673 MATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELRLKVMELETQVQVSTNQL 732
K ++ K++EEL + +V AL +L R ++L++ ++ QL
Sbjct: 481 STLHKSVV-----------KMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELLNRQL 529
Query: 733 RRQDEEARLLRENLDAALQRERALQTRQREFQHKYADLESKAKYESMQANIRNMEDAQRI 792
+D+E + LD+A L+++ + +LE+ + AN R+ E +I
Sbjct: 530 VAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEA-----LLVAN-RDKEYQSQI 583
Query: 793 AELETEVSEYKLKNEVMATEGELRNNNMDDSDRVRELQEQVAELKAEI 840
A E E LK + E ++ + D V + + V +L+A++
Sbjct: 584 ALQEKESEIQLLKEHLCLAENKMAIQSRD----VAQFRNVVTQLEADL 627
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 22/196 (11%)
Query: 656 KQEAPAAPVQSNVVSDIMATPKKLLRAWEGRSADMLKLDEELMTTRIREVEALTELKELR 715
K E A +Q NV + + K+ +E ++ +L E+M + + ++ T LR
Sbjct: 42 KYERHLAEIQGNV-KVLKSERDKIFLLYEQAQEEITRLRREMMKS-CKSPKSTTAHAILR 99
Query: 716 LKVMELETQVQVSTNQLRRQDEEARLLRENL----DAALQRERALQTRQREFQ---HKYA 768
+ET+ V+ LRR E LRE L + A + L+ R E + H
Sbjct: 100 ----RVETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLD 155
Query: 769 D--LESKAKYESMQANIRNMED-----AQRIAELETEVSEYKLKNEVMATEGELRNNNMD 821
D +E + M+ I +E A++ + E+E+ K +N + E N D
Sbjct: 156 DERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYE--NTEKD 213
Query: 822 DSDRVRELQEQVAELK 837
SD R L ++ EL+
Sbjct: 214 LSDTQRHLAKKKYELQ 229
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.130 0.360
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,118,535
Number of Sequences: 224733
Number of extensions: 3609309
Number of successful extensions: 21968
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 288
Number of HSP's successfully gapped in prelim test: 1421
Number of HSP's that attempted gapping in prelim test: 16360
Number of HSP's gapped (non-prelim): 5793
length of query: 894
length of database: 73,234,838
effective HSP length: 97
effective length of query: 797
effective length of database: 51,435,737
effective search space: 40994282389
effective search space used: 40994282389
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 70 (32.3 bits)
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