SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000538-TA|BGIBMGA000538-PA|IPR004481|K+-dependent
Na+/Ca+ exchanger related-protein, IPR004836|Sodium/calcium exchanger
protein, IPR004837|Sodium/calcium exchanger membrane region
         (459 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogast...   458   e-127
UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB....   320   4e-86
UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exch...   320   5e-86
UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-...   280   6e-74
UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; ...   266   1e-69
UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella ve...   263   8e-69
UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:1...   261   3e-68
UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-...   260   7e-68
UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-...   243   9e-63
UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute car...   241   3e-62
UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exch...   219   9e-56
UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exch...   193   7e-48
UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|...   193   9e-48
UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 pr...   176   9e-43
UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchang...   175   2e-42
UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium excha...   173   1e-41
UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchang...   167   4e-40
UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchang...   158   2e-37
UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isof...   157   6e-37
UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 pr...   154   4e-36
UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella ve...   151   3e-35
UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 pr...   151   4e-35
UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exch...   151   5e-35
UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exch...   150   9e-35
UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchang...   149   1e-34
UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute car...   145   2e-33
UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gamb...   142   2e-32
UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein,...   140   9e-32
UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve...   138   2e-31
UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome sh...   136   9e-31
UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaste...   134   3e-30
UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependen...   130   6e-29
UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogas...   126   1e-27
UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx...   125   2e-27
UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potass...   121   3e-26
UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:...   121   3e-26
UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - M...   120   1e-25
UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodiu...   119   2e-25
UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;...   118   3e-25
UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella ve...   118   3e-25
UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 pr...   118   3e-25
UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/pot...   117   7e-25
UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Eut...   116   1e-24
UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleosto...   115   3e-24
UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus nor...   115   3e-24
UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (N...   115   3e-24
UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N...   114   4e-24
UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchang...   109   2e-22
UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exch...   108   3e-22
UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n...   107   8e-22
UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amure...   106   1e-21
UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome s...   103   7e-21
UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to potassium-...   102   2e-20
UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calci...    98   4e-19
UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061...    97   6e-19
UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis ...    73   2e-11
UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger...    72   4e-11
UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-...    71   5e-11
UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella ve...    67   1e-09
UniRef50_Q4SAM5 Cluster: Chromosome undetermined SCAF14681, whol...    66   2e-09
UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole geno...    59   2e-07
UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a; ...    59   2e-07
UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus ...    56   1e-06
UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, e...    54   1e-05
UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 pre...    53   1e-05
UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to sodium-cal...    53   2e-05
UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeb...    53   2e-05
UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 pr...    53   2e-05
UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7 pre...    52   3e-05
UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein;...    51   6e-05
UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella ve...    51   6e-05
UniRef50_A0CH97 Cluster: Chromosome undetermined scaffold_18, wh...    51   6e-05
UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;...    50   1e-04
UniRef50_A0DA69 Cluster: Chromosome undetermined scaffold_43, wh...    50   1e-04
UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antip...    50   1e-04
UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:...    50   1e-04
UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1; Schizosa...    50   1e-04
UniRef50_Q59GN4 Cluster: Solute carrier family 8 (Sodium/calcium...    50   2e-04
UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (N...    50   2e-04
UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc...    49   2e-04
UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6; ...    49   2e-04
UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precu...    48   4e-04
UniRef50_UPI0000DB6F63 Cluster: PREDICTED: similar to solute car...    48   5e-04
UniRef50_Q2UDY9 Cluster: K+-dependent Na+:Ca2+ antiporter; n=1; ...    48   7e-04
UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family tr...    47   0.001
UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Re...    47   0.001
UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome s...    47   0.001
UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; ...    47   0.001
UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/cal...    47   0.001
UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2; ...    47   0.001
UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger prote...    46   0.002
UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-...    46   0.002
UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; A...    46   0.002
UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related ...    46   0.002
UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella ve...    46   0.002
UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces cap...    46   0.002
UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whol...    46   0.003
UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3; Caenorha...    46   0.003
UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precu...    45   0.004
UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-...    45   0.004
UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus...    45   0.004
UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr...    45   0.005
UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobac...    45   0.005
UniRef50_Q8KU52 Cluster: EF0109; n=1; Enterococcus faecalis|Rep:...    44   0.006
UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-...    44   0.006
UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-...    44   0.006
UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (N...    44   0.006
UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    44   0.008
UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2; Caeno...    44   0.008
UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, wh...    44   0.008
UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; ...    44   0.008
UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1; ...    44   0.011
UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whol...    43   0.015
UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyce...    43   0.015
UniRef50_Q2HE40 Cluster: Putative uncharacterized protein; n=1; ...    43   0.015
UniRef50_Q4RST3 Cluster: Chromosome 12 SCAF14999, whole genome s...    43   0.020
UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane regio...    43   0.020
UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; ...    42   0.026
UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger prote...    42   0.026
UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis th...    42   0.026
UniRef50_Q9VC56 Cluster: CG5794-PD, isoform D; n=7; Eukaryota|Re...    42   0.026
UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na...    42   0.026
UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2; ...    42   0.026
UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2; ...    42   0.026
UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: ...    42   0.034
UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; T...    42   0.034
UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    42   0.034
UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; ...    42   0.034
UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter therma...    42   0.034
UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; H...    42   0.034
UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum sy...    42   0.034
UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|...    42   0.045
UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein B14D6....    42   0.045
UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1; ...    42   0.045
UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; ...    41   0.060
UniRef50_A5Z8F4 Cluster: Putative uncharacterized protein; n=1; ...    41   0.060
UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P...    41   0.060
UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein...    41   0.060
UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillat...    41   0.060
UniRef50_Q6JAE1 Cluster: Putative K-exchanger-like protein; n=1;...    41   0.060
UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenor...    41   0.060
UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halob...    41   0.060
UniRef50_UPI000049A3AC Cluster: hypothetical protein 24.t00059; ...    41   0.079
UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep...    41   0.079
UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteob...    41   0.079
UniRef50_A2F8N8 Cluster: Putative uncharacterized protein; n=2; ...    41   0.079
UniRef50_UPI0000498A17 Cluster: sodium/calcium exchanger protein...    40   0.10 
UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-...    40   0.10 
UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    40   0.10 
UniRef50_A0V1B3 Cluster: Putative uncharacterized protein; n=1; ...    40   0.10 
UniRef50_UPI0000E494AB Cluster: PREDICTED: hypothetical protein;...    40   0.14 
UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteob...    40   0.14 
UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacte...    40   0.14 
UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; ...    40   0.14 
UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; R...    40   0.14 
UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-...    40   0.14 
UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella ve...    40   0.14 
UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriacea...    40   0.14 
UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Ente...    40   0.14 
UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    40   0.18 
UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamm...    40   0.18 
UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    40   0.18 
UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    40   0.18 
UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    40   0.18 
UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole gen...    40   0.18 
UniRef50_Q59NL4 Cluster: Putative uncharacterized protein; n=1; ...    40   0.18 
UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; M...    40   0.18 
UniRef50_UPI00006CB3BD Cluster: hypothetical protein TTHERM_0047...    39   0.24 
UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-...    39   0.24 
UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger related-...    39   0.24 
UniRef50_A2FHT1 Cluster: Putative uncharacterized protein; n=1; ...    39   0.24 
UniRef50_A2DZZ4 Cluster: Putative uncharacterized protein; n=1; ...    39   0.24 
UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; ...    39   0.24 
UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane pro...    39   0.24 
UniRef50_UPI00006CB708 Cluster: hypothetical protein TTHERM_0049...    39   0.32 
UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-...    39   0.32 
UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like pro...    39   0.32 
UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    39   0.32 
UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; ...    39   0.32 
UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;...    39   0.32 
UniRef50_UPI00006CE59A Cluster: probable Mg2+-specific channel-l...    38   0.42 
UniRef50_UPI000023F701 Cluster: hypothetical protein FG10084.1; ...    38   0.42 
UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.42 
UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; ...    38   0.42 
UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; ...    38   0.42 
UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; ...    38   0.42 
UniRef50_A4RX12 Cluster: CaCA family transporter: sodium ion/pot...    38   0.42 
UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces c...    38   0.42 
UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1; ...    38   0.42 
UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloa...    38   0.42 
UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca exch...    38   0.55 
UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.55 
UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.55 
UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.55 
UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.55 
UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;...    38   0.55 
UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; ...    38   0.55 
UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; ...    38   0.55 
UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; S...    38   0.55 
UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|...    38   0.55 
UniRef50_Q4YXS7 Cluster: Erythrocyte membrane protein 3, putativ...    38   0.55 
UniRef50_A2G605 Cluster: Putative uncharacterized protein; n=1; ...    38   0.55 
UniRef50_Q59TE2 Cluster: Putative uncharacterized protein SWI3; ...    38   0.55 
UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.73 
UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.73 
UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomon...    38   0.73 
UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein...    38   0.73 
UniRef50_A2Q9Q0 Cluster: Contig An01c0300, complete genome; n=1;...    38   0.73 
UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2; ...    38   0.73 
UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; ...    38   0.73 
UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; C...    38   0.73 
UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1; Methanobrevib...    38   0.73 
UniRef50_UPI00004D858F Cluster: serine arginine-rich pre-mRNA sp...    37   0.97 
UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    37   0.97 
UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; F...    37   0.97 
UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-...    37   0.97 
UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    37   0.97 
UniRef50_A7NTE6 Cluster: Chromosome chr18 scaffold_1, whole geno...    37   0.97 
UniRef50_Q6CSX0 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    37   0.97 
UniRef50_A7THF3 Cluster: Putative uncharacterized protein; n=1; ...    37   0.97 
UniRef50_Q9NEU2 Cluster: Protein SDA1 homolog; n=4; Caenorhabdit...    37   0.97 
UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan...    37   1.3  
UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria...    37   1.3  
UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-...    37   1.3  
UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; ...    37   1.3  
UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; A...    37   1.3  
UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    37   1.3  
UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriph...    37   1.3  
UniRef50_Q55CW2 Cluster: SAM domain-containing protein; n=1; Dic...    37   1.3  
UniRef50_A2FNC4 Cluster: Variable membrane protein, putative; n=...    37   1.3  
UniRef50_A2E032 Cluster: Putative uncharacterized protein; n=1; ...    37   1.3  
UniRef50_Q5A5C0 Cluster: Potential Sit4 phosphatase complex comp...    37   1.3  
UniRef50_A5E2T9 Cluster: Putative uncharacterized protein; n=2; ...    37   1.3  
UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:...    37   1.3  
UniRef50_UPI000150A186 Cluster: Zinc finger, C2H2 type family pr...    36   1.7  
UniRef50_Q4A126 Cluster: Putative uncharacterized protein; n=1; ...    36   1.7  
UniRef50_Q8KK76 Cluster: Putative uncharacterized protein orf66;...    36   1.7  
UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P...    36   1.7  
UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger related-...    36   1.7  
UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Re...    36   1.7  
UniRef50_Q337V5 Cluster: Sodium/calcium exchanger protein, expre...    36   1.7  
UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:...    36   1.7  
UniRef50_Q6LFD0 Cluster: Putative myosin-like protein; n=2; cell...    36   1.7  
UniRef50_Q54G75 Cluster: Putative uncharacterized protein; n=1; ...    36   1.7  
UniRef50_Q23ZF3 Cluster: UV-endonuclease uvde family protein; n=...    36   1.7  
UniRef50_Q23YU2 Cluster: Putative uncharacterized protein; n=1; ...    36   1.7  
UniRef50_Q22MU0 Cluster: Putative uncharacterized protein; n=1; ...    36   1.7  
UniRef50_A5K441 Cluster: Putative uncharacterized protein; n=2; ...    36   1.7  
UniRef50_Q6BIV5 Cluster: Similar to sp|P38759 Saccharomyces cere...    36   1.7  
UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep: Myo...    36   1.7  
UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; ...    36   1.7  
UniRef50_UPI0000F1F30E Cluster: PREDICTED: hypothetical protein;...    36   2.2  
UniRef50_UPI0000F1D8B9 Cluster: PREDICTED: similar to Rho GTPase...    36   2.2  
UniRef50_UPI0000E49984 Cluster: PREDICTED: similar to bromodomai...    36   2.2  
UniRef50_Q800H4 Cluster: Novel protein similar to human matrin 3...    36   2.2  
UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisph...    36   2.2  
UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; A...    36   2.2  
UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole geno...    36   2.2  
UniRef50_A5KAV0 Cluster: Merozoite surface protein 3 gamma (MSP3...    36   2.2  
UniRef50_UPI00006CE921 Cluster: hypothetical protein TTHERM_0056...    36   3.0  
UniRef50_UPI000049872F Cluster: hypothetical protein 882.t00001;...    36   3.0  
UniRef50_UPI000023F113 Cluster: hypothetical protein FG10529.1; ...    36   3.0  
UniRef50_Q4T3X3 Cluster: Chromosome 2 SCAF9897, whole genome sho...    36   3.0  
UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; ...    36   3.0  
UniRef50_Q189V4 Cluster: Ca2+/Na+ antiporter; n=3; Clostridium d...    36   3.0  
UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;...    36   3.0  
UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;...    36   3.0  
UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneum...    36   3.0  
UniRef50_A5GJM9 Cluster: Ca2+/Na+ antiporter; n=23; Cyanobacteri...    36   3.0  
UniRef50_Q0DZ55 Cluster: Os02g0644900 protein; n=3; Oryza sativa...    36   3.0  
UniRef50_A7Q0D0 Cluster: Chromosome chr7 scaffold_42, whole geno...    36   3.0  
UniRef50_Q54IP8 Cluster: Putative uncharacterized protein; n=1; ...    36   3.0  
UniRef50_A2FDS6 Cluster: Variable membrane protein, putative; n=...    36   3.0  
UniRef50_A2EVM3 Cluster: Viral A-type inclusion protein, putativ...    36   3.0  
UniRef50_A2ETV5 Cluster: Putative uncharacterized protein; n=1; ...    36   3.0  
UniRef50_A2E9E1 Cluster: Putative uncharacterized protein; n=1; ...    36   3.0  
UniRef50_A0BP45 Cluster: Chromosome undetermined scaffold_12, wh...    36   3.0  
UniRef50_UPI00015B6253 Cluster: PREDICTED: similar to CG33715-PD...    35   3.9  
UniRef50_UPI0001555A51 Cluster: PREDICTED: similar to solute car...    35   3.9  
UniRef50_UPI00006D0DB6 Cluster: Kinesin motor domain containing ...    35   3.9  
UniRef50_UPI00004990BF Cluster: hypothetical protein 1.t00068; n...    35   3.9  
UniRef50_Q9YH83 Cluster: Sodium-calcium exchanger; n=31; Coeloma...    35   3.9  
UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protei...    35   3.9  
UniRef50_A4BIS1 Cluster: Still frameshift probable component of ...    35   3.9  
UniRef50_Q9NDI9 Cluster: Merozoite surface protein 3g; n=1; Plas...    35   3.9  
UniRef50_Q8IKF6 Cluster: Putative uncharacterized protein; n=1; ...    35   3.9  
UniRef50_Q7PDT1 Cluster: Formin Homology 2 Domain, putative; n=8...    35   3.9  
UniRef50_Q611S6 Cluster: Putative uncharacterized protein CBG169...    35   3.9  
UniRef50_Q4Z134 Cluster: Putative uncharacterized protein; n=1; ...    35   3.9  
UniRef50_Q22PL1 Cluster: MNN4 protein, putative; n=3; Tetrahymen...    35   3.9  
UniRef50_A2G927 Cluster: Putative uncharacterized protein; n=1; ...    35   3.9  
UniRef50_A2DJQ2 Cluster: Putative uncharacterized protein; n=1; ...    35   3.9  
UniRef50_A2DFD4 Cluster: Putative uncharacterized protein; n=2; ...    35   3.9  
UniRef50_A2DCD2 Cluster: Putative uncharacterized protein; n=1; ...    35   3.9  
UniRef50_A0CQH1 Cluster: Chromosome undetermined scaffold_24, wh...    35   3.9  
UniRef50_A0C569 Cluster: Chromosome undetermined scaffold_15, wh...    35   3.9  
UniRef50_A0BTS9 Cluster: Chromosome undetermined scaffold_128, w...    35   3.9  
UniRef50_Q5AKZ6 Cluster: Putative uncharacterized protein; n=1; ...    35   3.9  
UniRef50_A3GGW1 Cluster: Sodium/calcium exchanger protein; n=2; ...    35   3.9  
UniRef50_UPI0000E481C5 Cluster: PREDICTED: hypothetical protein;...    35   5.2  
UniRef50_UPI00006CC9FF Cluster: NLI interacting factor-like phos...    35   5.2  
UniRef50_UPI0000498FCC Cluster: U2 snRNP auxiliary factor large ...    35   5.2  
UniRef50_Q4SI51 Cluster: Chromosome 5 SCAF14581, whole genome sh...    35   5.2  
UniRef50_Q8JS31 Cluster: Putative uncharacterized protein PhopGV...    35   5.2  
UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-...    35   5.2  
UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antip...    35   5.2  
UniRef50_A3TSR9 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_A0VUH2 Cluster: Sodium/calcium exchanger membrane regio...    35   5.2  
UniRef50_Q9VL48 Cluster: CG13131-PA; n=2; Drosophila melanogaste...    35   5.2  
UniRef50_Q8IIN2 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_Q8IHS4 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_Q8I511 Cluster: DEAD/DEAH box helicase, putative; n=6; ...    35   5.2  
UniRef50_Q7RRD1 Cluster: Putative uncharacterized protein PY0080...    35   5.2  
UniRef50_Q612K1 Cluster: Putative uncharacterized protein CBG166...    35   5.2  
UniRef50_Q54LA6 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_Q4YRZ4 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_A2G4G3 Cluster: Auxin Efflux Carrier family protein; n=...    35   5.2  
UniRef50_A2FYM4 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_A2FMK4 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_A2DT19 Cluster: Putative uncharacterized protein; n=1; ...    35   5.2  
UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, who...    35   5.2  
UniRef50_A0CFE1 Cluster: Chromosome undetermined scaffold_175, w...    35   5.2  
UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; ...    35   5.2  
UniRef50_Q9C2H4 Cluster: Putative uncharacterized protein 93G11....    35   5.2  
UniRef50_Q2UEZ7 Cluster: Predicted protein; n=4; Aspergillus|Rep...    35   5.2  
UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; ...    35   5.2  
UniRef50_Q3IN47 Cluster: Probable cell surface glycoprotein; n=1...    35   5.2  
UniRef50_Q9HC35 Cluster: Echinoderm microtubule-associated prote...    35   5.2  
UniRef50_UPI000023E8AF Cluster: hypothetical protein FG08070.1; ...    34   6.8  
UniRef50_UPI0000E4ED42 Cluster: X-linked retinitis pigmentosa GT...    34   6.8  
UniRef50_Q4TEE8 Cluster: Chromosome undetermined SCAF5461, whole...    34   6.8  
UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH04...    34   6.8  
UniRef50_Q6FEF3 Cluster: Vitamin B12 receptor; n=2; Acinetobacte...    34   6.8  
UniRef50_Q5HNF3 Cluster: Cell wall surface anchor family protein...    34   6.8  
UniRef50_Q4HQJ8 Cluster: Poly E-rich protein, putative; n=1; Cam...    34   6.8  
UniRef50_Q019W0 Cluster: Putative sodium/calcium exchanger prote...    34   6.8  
UniRef50_Q7RTC8 Cluster: Cation-transporting ATPase; n=10; Eukar...    34   6.8  
UniRef50_Q7RT66 Cluster: Putative uncharacterized protein PY0012...    34   6.8  
UniRef50_Q55C97 Cluster: Putative uncharacterized protein; n=1; ...    34   6.8  
UniRef50_Q54ZS3 Cluster: Putative uncharacterized protein; n=2; ...    34   6.8  
UniRef50_Q54X08 Cluster: Myb domain-containing protein; n=1; Dic...    34   6.8  
UniRef50_Q54AQ1 Cluster: Xeroderma pigmentosum group G (XPG) fam...    34   6.8  
UniRef50_Q4Y8M1 Cluster: Putative uncharacterized protein; n=4; ...    34   6.8  
UniRef50_Q23KL3 Cluster: Putative uncharacterized protein; n=1; ...    34   6.8  
UniRef50_Q17IV5 Cluster: Chromodomain helicase DNA binding prote...    34   6.8  
UniRef50_A7SKD8 Cluster: Predicted protein; n=2; Nematostella ve...    34   6.8  
UniRef50_A2G287 Cluster: Beige/BEACH domain containing protein; ...    34   6.8  
UniRef50_A2EBY4 Cluster: Putative uncharacterized protein; n=1; ...    34   6.8  
UniRef50_A0DKK0 Cluster: Chromosome undetermined scaffold_54, wh...    34   6.8  
UniRef50_A0CQY1 Cluster: Chromosome undetermined scaffold_241, w...    34   6.8  
UniRef50_Q5JXK9 Cluster: PHD finger protein 20; n=2; Eutheria|Re...    34   6.8  
UniRef50_Q6CBD5 Cluster: Similar to tr|Q91255 Petromyzon marinus...    34   6.8  
UniRef50_Q6BUF0 Cluster: Similarities with sp|P32466 Saccharomyc...    34   6.8  
UniRef50_A7TER5 Cluster: Putative uncharacterized protein; n=1; ...    34   6.8  
UniRef50_A7EES1 Cluster: Putative uncharacterized protein; n=1; ...    34   6.8  
UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091...    34   6.8  
UniRef50_Q9BVI0 Cluster: PHD finger protein 20; n=33; Eutheria|R...    34   6.8  
UniRef50_UPI000150A4B5 Cluster: SET domain containing protein; n...    34   9.0  
UniRef50_UPI0000F1EF2D Cluster: PREDICTED: similar to RPGR; n=2;...    34   9.0  
UniRef50_UPI0000E4778D Cluster: PREDICTED: hypothetical protein;...    34   9.0  
UniRef50_UPI0000D56B63 Cluster: PREDICTED: similar to CG12301-PA...    34   9.0  
UniRef50_UPI00006CB381 Cluster: hypothetical protein TTHERM_0065...    34   9.0  
UniRef50_UPI0000ECA833 Cluster: PREDICTED: Gallus gallus similar...    34   9.0  
UniRef50_Q4T999 Cluster: Chromosome undetermined SCAF7612, whole...    34   9.0  
UniRef50_Q4SWH1 Cluster: Chromosome undetermined SCAF13621, whol...    34   9.0  
UniRef50_Q11LZ9 Cluster: Sensor protein; n=1; Mesorhizobium sp. ...    34   9.0  
UniRef50_A6DM68 Cluster: Putative uncharacterized protein; n=1; ...    34   9.0  
UniRef50_A5VW73 Cluster: Phage scaffold protein; n=4; Escherichi...    34   9.0  
UniRef50_Q8IDY5 Cluster: Putative uncharacterized protein PF13_0...    34   9.0  
UniRef50_Q8I2V5 Cluster: Putative uncharacterized protein PFI097...    34   9.0  
UniRef50_Q7RDA2 Cluster: Krox-like protein; n=3; Plasmodium (Vin...    34   9.0  
UniRef50_Q6BFU1 Cluster: Putative uncharacterized protein; n=1; ...    34   9.0  
UniRef50_Q24DQ7 Cluster: Putative uncharacterized protein; n=1; ...    34   9.0  
UniRef50_Q179R7 Cluster: Putative uncharacterized protein; n=1; ...    34   9.0  
UniRef50_A7S9W3 Cluster: Predicted protein; n=2; Nematostella ve...    34   9.0  
UniRef50_A2FKT9 Cluster: Viral A-type inclusion protein, putativ...    34   9.0  
UniRef50_A2E7M0 Cluster: Putative uncharacterized protein; n=1; ...    34   9.0  
UniRef50_A2E7B0 Cluster: Putative uncharacterized protein; n=5; ...    34   9.0  
UniRef50_Q7RYV1 Cluster: Putative uncharacterized protein NCU064...    34   9.0  
UniRef50_Q6BSX2 Cluster: Similar to CA1231|IPF11817 Candida albi...    34   9.0  
UniRef50_O42882 Cluster: Conserved fungal protein; n=1; Schizosa...    34   9.0  

>UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila
           melanogaster|Rep: CG2893-PC.3 - Drosophila melanogaster
           (Fruit fly)
          Length = 542

 Score =  458 bits (1128), Expect = e-127
 Identities = 235/463 (50%), Positives = 291/463 (62%), Gaps = 8/463 (1%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           M+NDV            PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM
Sbjct: 80  MSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 139

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
            +PLDWWPLTRD +AYG+TV+ILIC++HDE V+WYEA +LVSLY VY+ +MY+DK  Q  
Sbjct: 140 TIPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKC 199

Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIK-----TSPL 175
           AKG  K   +  + +      +N  + +      +I   +     + G  K     TS  
Sbjct: 200 AKGGVKQARSRSRSSNCSIHTKNSNEKEPELVENRICQNMANIQLNGGLNKEQAKATSTS 259

Query: 176 RQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDV 235
                   + +  ++  +S +         + + S P  +   +P ++    +       
Sbjct: 260 GAGTTAISITTSTMTTTLSTTHSAGGGGGAVGLCSGPGAIVQMAPLDDAEAESHVAVAAA 319

Query: 236 EDGSEN---SLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCI 292
           ++G +    SL  +P +KSC A+ T ++ WPIHL+F   IPDC+K +    FPLTFIMCI
Sbjct: 320 DEGRKEEGYSLLSYPKDKSCFAQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCI 379

Query: 293 VWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXX 352
           VWIGSLSY+VAWMITIIGDTL IPDSVMGITFLAAGTSVPEAVSSVIVAK+         
Sbjct: 380 VWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICN 439

Query: 353 XXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWF 412
                TFDILLCLG+PWLIKA   P +PG  +V INS GLEYSAI            F  
Sbjct: 440 SIGSNTFDILLCLGVPWLIKAVFFPIQPGQNYVAINSAGLEYSAITLLSTLFLLYLTFST 499

Query: 413 NKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNVRTCKRA 455
           NKFKLD  VG ACL MY +F++ A+LIELNVFF VN+ TC R+
Sbjct: 500 NKFKLDKKVGTACLVMYLVFMVFASLIELNVFFRVNLPTCGRS 542


>UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.3;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG2893-PB.3 - Tribolium castaneum
          Length = 480

 Score =  320 bits (787), Expect = 4e-86
 Identities = 156/292 (53%), Positives = 195/292 (66%), Gaps = 5/292 (1%)

Query: 168 GNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSK---PNEME--IASPEE 222
           G  K++    D+  + +E+ +    +  ++E KD + N + ++    P+ +   +  PE 
Sbjct: 189 GGFKSAQPPHDSTPQSIEAAEAHLPLQPNKEIKDISDNHNTENVVVVPSHLNGSLKVPEA 248

Query: 223 NLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKN 282
              +    + T++ +   +SLWKWP+ +S   + T ++TWPIHL+FLFTIPDCEKPRFK 
Sbjct: 249 ETEEAKKTEPTNMVEDEPHSLWKWPAGRSKFTQFTWVITWPIHLIFLFTIPDCEKPRFKK 308

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           WFPLTFIMCI+WIGSLSY+VAWMITIIGDTL IPDSVMGITFLAAGTS+PEAVSSVIVAK
Sbjct: 309 WFPLTFIMCIIWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSIPEAVSSVIVAK 368

Query: 343 QXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXX 402
           Q              TFDILLCLGLPW IKA+  P   G +WV INS G+EYSAI     
Sbjct: 369 QGHGSMGISNSIGSNTFDILLCLGLPWFIKATFMPTIAGKHWVGINSAGIEYSAISLLSS 428

Query: 403 XXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNVRTCKR 454
                  F  NKF+LD  VGR CL MYA+FLILA+LIELN FF VN+ TC R
Sbjct: 429 LLLLYLVFAVNKFRLDKRVGRICLLMYAIFLILASLIELNAFFRVNLPTCGR 480



 Score =  202 bits (492), Expect = 2e-50
 Identities = 97/130 (74%), Positives = 103/130 (79%), Gaps = 4/130 (3%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           M+ DV            PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG+
Sbjct: 63  MSADVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGL 122

Query: 61  ----VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKP 116
               VVPLDWWPLTRDCLAYGITVSILICIIHDE V+WYEA  LV LY VYI IMY+DK 
Sbjct: 123 CGVKVVPLDWWPLTRDCLAYGITVSILICIIHDERVEWYEALTLVLLYTVYILIMYFDKS 182

Query: 117 IQNFAKGSWK 126
           IQ  A+G +K
Sbjct: 183 IQRCARGGFK 192


>UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=1; Aedes aegypti|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 492

 Score =  320 bits (786), Expect = 5e-86
 Identities = 166/297 (55%), Positives = 195/297 (65%), Gaps = 9/297 (3%)

Query: 160 IEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIAS 219
           I++RH       T+ L +D +     S       SAS E    ++N D   K      A 
Sbjct: 203 IKRRHSAGSMNGTASLDEDDQRPPPPSPSTPPVSSASAESMKNSLNGDHSEKD-----AG 257

Query: 220 PEENLYQPTAEDNTDVEDGSENS--LWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEK 277
              N    T  ++ DV D  +    L+K+PS +S L + + I+TWPI+L+F+FTIP+C K
Sbjct: 258 ALGN--GATGGESVDVSDDKDEEFQLFKYPSGQSKLRQFSWIITWPIYLLFVFTIPNCAK 315

Query: 278 PRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSS 337
           PR+K WFPLTFIMCIVWIGSLSY+VAWMITIIGDTL IPDSVMGITFLAAGTSVPEAVSS
Sbjct: 316 PRYKKWFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSS 375

Query: 338 VIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAI 397
           VIVAKQ              TFDILLCLGLPW IKA+ +P E GH+WV INS GLEYSAI
Sbjct: 376 VIVAKQGYGSMGISNSIGSNTFDILLCLGLPWFIKAAFSPIEKGHHWVGINSAGLEYSAI 435

Query: 398 XXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNVRTCKR 454
                       FW NKF+LD  VG ACL MYA+FLILA+LIELNVFFPVN+ TC R
Sbjct: 436 SLLSTLLMLYIAFWLNKFRLDRRVGYACLIMYAVFLILASLIELNVFFPVNLPTCVR 492



 Score =  207 bits (506), Expect = 4e-52
 Identities = 95/122 (77%), Positives = 101/122 (82%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           M+NDV            PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM
Sbjct: 1   MSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           VVPLDWWPLTRDCLAYGITV+ILICIIHDE V+WYEA +LV LY VYI +MYYDK  Q  
Sbjct: 61  VVPLDWWPLTRDCLAYGITVAILICIIHDERVEWYEALILVLLYIVYIAVMYYDKAFQKC 120

Query: 121 AK 122
           A+
Sbjct: 121 AR 122


>UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to
           potassium-dependent Na/Ca exchanger NCKX3; n=2;
           Deuterostomia|Rep: PREDICTED: similar to
           potassium-dependent Na/Ca exchanger NCKX3 -
           Strongylocentrotus purpuratus
          Length = 570

 Score =  280 bits (686), Expect = 6e-74
 Identities = 162/455 (35%), Positives = 231/455 (50%), Gaps = 21/455 (4%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +T DV            PELF +VIG FI +GD+GVGTIVGSAVFNIL +   CG+ AG 
Sbjct: 134 LTEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGLCGLFAGQ 193

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           VV L WWPL RD L Y I+V  L+ +I D Y+ WYEA +++ +Y  Y+ IM +D  I   
Sbjct: 194 VVHLSWWPLFRDTLVYAISVVTLVLVIRDGYINWYEALVMLLMYLCYVIIMCFD--IITP 251

Query: 121 AKGSWKWVSNMFKDNEEKQDAE-NGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDA 179
              +    +N  K   E+ D E +    +L+     + + + ++      ++T+      
Sbjct: 252 LNATEDITTNGEKKEVEEVDGEFSNSPKRLTFSDAGLRLMLTKQFPARTRLRTACWLIIT 311

Query: 180 KEKILESVDVSDKVSASEEGKDKNVNIDMDSK-PNEMEIASPEENLYQPTAEDNTDVEDG 238
           ++K LE+ +   K   +   +      + +   P    I   E        E   DV  G
Sbjct: 312 EQKQLEA-ESGGKFPTTYTHRPSLPETEKNGNVPRSDSICKDESVDLSIDKEGTEDVISG 370

Query: 239 SENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSL 298
             N L KW            IVT PI ++  FTIPDC + RF  W+ +TF + + WI   
Sbjct: 371 IINIL-KW------------IVTLPICILLFFTIPDCRRKRFDRWYMVTFFISVAWIAIF 417

Query: 299 SYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXT 358
           SY++ WM+  IG TL IPD++MGITFLAAGTSVP+A++S++VA++               
Sbjct: 418 SYVMVWMVAYIGHTLHIPDTIMGITFLAAGTSVPDAIASLLVAREGLGDMAVSNSIGSNV 477

Query: 359 FDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLD 418
           FDIL+ L LPW IK +          +KINS GL YS +              FNK++LD
Sbjct: 478 FDILIGLALPWFIKTAFVSYGTR---IKINSKGLLYSVLLLFASVTATILAIHFNKWRLD 534

Query: 419 AAVGRACLAMYAMFLILATLIELNVFFPVNVRTCK 453
             +G      Y +FL  + ++E+NVF  VN   CK
Sbjct: 535 KRLGVLLTCFYVVFLSFSIMVEMNVFGYVNPPMCK 569



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 20/59 (33%), Positives = 29/59 (49%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           I + L + + V G TF+AAG+S PE  +SVI                   F+IL+ +GL
Sbjct: 128 ICENLSLTEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGL 186


>UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           RE34149p - Nasonia vitripennis
          Length = 542

 Score =  266 bits (651), Expect = 1e-69
 Identities = 156/449 (34%), Positives = 225/449 (50%), Gaps = 23/449 (5%)

Query: 4   DVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP 63
           DV            PELFVNV+GTF+TE D+GVG +VG AVFN  A  A   + A   + 
Sbjct: 117 DVAGATFLATASCFPELFVNVVGTFLTESDLGVGAVVGGAVFNTFATPAVGALFAAKGIQ 176

Query: 64  LDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKG 123
           L W  L+RDC+ Y  +V +L+ ++ D  V WYE+ +L+ L+  Y  +++ +  I    + 
Sbjct: 177 LQWHILSRDCVIYSFSVGVLVLVMWDGLVTWYESVILLFLFASYFTLLFVNDSIVRVFR- 235

Query: 124 SWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKI 183
                   F  NE K  A+   D+K         V  E      G  K      +   + 
Sbjct: 236 ------RFFSRNEVKP-ADTPIDVKAEA------VKHENYQMPFGTYKPY-FHGELVTEY 281

Query: 184 LESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSL 243
             S+      S SE G +    +++ ++P    I+   E    PT    T       +++
Sbjct: 282 RNSLSKIKAQSNSEAGVNHKPILEVYTEPGIKTISRASETTSAPTT---TSKSCNLSDTI 338

Query: 244 WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVA 303
           + WPS  S   K   + TWPI L+   TIPD    R + ++P+TFIMC++WI   SY+V+
Sbjct: 339 FMWPSKSSTSEKFWFLFTWPIKLILFVTIPDSRYKRLRKFYPITFIMCVMWIAVSSYMVS 398

Query: 304 WMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILL 363
           WM T++GDT+ IPDSVMGITFL+AG ++PE VS VI+++Q              T DILL
Sbjct: 399 WMTTVVGDTVGIPDSVMGITFLSAGGNLPEMVSIVILSRQGHGDMAMSNTIGANTLDILL 458

Query: 364 CLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGR 423
           CL LPW I+  +T  +     V I S  L YS +                 F L+  VG 
Sbjct: 459 CLSLPWAIRNFMTGKD-----VTIVSSALVYSNLSIIVCVAGFYAVTALYGFILNKRVGI 513

Query: 424 ACLAMYAMFLILATLIELNVFFPVNVRTC 452
            CL MY +FL+++ ++ELNVFF VN+  C
Sbjct: 514 ICLIMYCLFLVISVMMELNVFFFVNLPMC 542


>UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 490

 Score =  263 bits (644), Expect = 8e-69
 Identities = 156/455 (34%), Positives = 236/455 (51%), Gaps = 31/455 (6%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +  DV            PELF +VIG FIT+GDIGVGTI+GSAVFN+L V   CG+GAG 
Sbjct: 60  LQTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGT 119

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V+ L WWP+ RD + Y  ++  L+ ++ D  V W EA  +VS Y VY+ IMY++  I+ +
Sbjct: 120 VLYLAWWPMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLLIMYFNPRIEAY 179

Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAK 180
                K  +  +K +  +Q A             K D P++Q               + +
Sbjct: 180 LYRVTKTTTPEYKSDLHEQKATK----------TKYD-PVQQTDN------------EVE 216

Query: 181 EKILESVDVSDKVSASEE-GKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNT--DVED 237
            +IL++V+ SD  +     G+   +  + +   + + +   E   +    E +   DV D
Sbjct: 217 AEILDNVNGSDDTTKKGLLGRIYELYFNKEKVKSPLIVGFGEHLAHHHEYEQHVPHDVPD 276

Query: 238 GSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGS 297
            +  S +  P N     +I  ++  PI+L F  TIPD +KP  + W  L+FI+CIVWIG 
Sbjct: 277 LTLGSPFSPPEN--VWPRICWVLGLPINLSFFLTIPDVKKPSCEKWVVLSFIICIVWIGV 334

Query: 298 LSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXX 357
            SY++ WM+T+IG T +IPDSVMG++ +A G+SVP+ +SS+ VA++              
Sbjct: 335 TSYVLVWMVTVIGYTFLIPDSVMGLSLVAFGSSVPDCLSSLFVARKGDGDMAVSHTVGSN 394

Query: 358 TFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKL 417
            FDILLCLG+PWLIK ++   +     V INS GL  S               W+ K+ L
Sbjct: 395 VFDILLCLGIPWLIKTTVWEYDSS---VVINSHGLFISCFFILGSIAVTLIIIWYYKWTL 451

Query: 418 DAAVGRACLAMYAMFLILATLIELNVFFPVNVRTC 452
           +  VG   L  Y +F+ ++ ++E+N F   N   C
Sbjct: 452 NKKVGCIYLVFYFIFMSISVVVEMNAFGNFNPPMC 486


>UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep:
           Zgc:112072 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 569

 Score =  261 bits (639), Expect = 3e-68
 Identities = 163/456 (35%), Positives = 236/456 (51%), Gaps = 14/456 (3%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FIT GD+GVGTIVGSAVFNIL +   CGI AG 
Sbjct: 119 LSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQ 178

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           VV L  + + RD   Y I+V  LI  I+D+ + W+E+ +L+ +Y  YI +M ++  +QN 
Sbjct: 179 VVFLTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLGYIIVMKFNTSLQNL 238

Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTH--ILKIDVPIEQRHQHNGNIKTSPLRQD 178
             G  K    +   N    + E  K  K+ T   ++ +D  +     H      + LR  
Sbjct: 239 FNG--KEDKRVTNGNAVSSEMEPVKPNKIYTRGSVVMVDEMMNSSPPHY-RFPEAGLRVM 295

Query: 179 AKEKI--LESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVE 236
                     + ++ ++  +E+ +       +DS     + A   EN     AED    E
Sbjct: 296 ITNHFGPKTRLRMASRLIINEQQRLVKSANGVDSVLVSDQKADTMEN--GNVAEDKLSEE 353

Query: 237 DGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIG 296
             +E S ++ P       K    ++WPI L+  FTIP+C K R++  F L+F +  VWI 
Sbjct: 354 QENEISPFRLPEGAVDTVKF--FISWPISLLLYFTIPNCAKKRWECCFMLSFFLSTVWIA 411

Query: 297 SLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXX 356
           + SYI+ WM+TI+G TL IPD +MGITFLAAGTSVP+ ++S+IVA+Q             
Sbjct: 412 AFSYILVWMVTIVGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGS 471

Query: 357 XTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFK 416
             FDIL+ LG+PW I+   T A      VKINS GL YS +               N+++
Sbjct: 472 NVFDILVGLGVPWGIQ---TMAVNYGSVVKINSRGLVYSVVLLLGSVALTVLGIHVNRWR 528

Query: 417 LDAAVGRACLAMYAMFLILATLIELNVFFPVNVRTC 452
           LD  +G   L +YA+FL  + +IE NVF  VN+  C
Sbjct: 529 LDLRLGIYVLVLYAVFLTFSIMIEYNVFTFVNLPMC 564


>UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative -
           Nasonia vitripennis
          Length = 692

 Score =  260 bits (636), Expect = 7e-68
 Identities = 155/479 (32%), Positives = 238/479 (49%), Gaps = 31/479 (6%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PEL   VIG F  + DIGV  ++GSAVFNI+ V + CG+ +  
Sbjct: 214 LSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAVFNIMFVISVCGLCSST 273

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V  L+WWPL RDC  Y I++ +++  I +E + W EA  ++ +YGVY   + ++  ++ +
Sbjct: 274 VSKLNWWPLCRDCFFYFISILVMLGTIANESISWGEALFMLIMYGVYCVALAFNSTLERW 333

Query: 121 AKG-SWKWVSNMFKDNEEKQDAENGKDLK------LSTHILKIDVPIEQRHQHNGNIKTS 173
           AK  +  W+    +   E+      K L+         +   +D P        G+   +
Sbjct: 334 AKSYNIPWLPKDEEQPAEQSALVTYKSLQEERQGYTDPNTTAVDQPKTNEGYSTGDAGYN 393

Query: 174 PLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSK------PNEMEIASP-----EE 222
              QD+    +   D +D  S+  +    N N    S       P++ ++ SP     +E
Sbjct: 394 QW-QDSNAPAVNQWDPNDAWSSGGQADQWNPNDAWSSDHHQQQYPSQQQMQSPPQQQQQE 452

Query: 223 NLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTW---------PIHLVFLFTIP 273
              Q  A+     +     +    P+  S L K T   TW         PIH +   T+P
Sbjct: 453 QQQQQPAKPPVPKQPQYYKAKEPDPNEVSPLVKPTDGGTWGLFTWGLVYPIHYMGRLTMP 512

Query: 274 DCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPE 333
           DC + +++NW+P TF + ++WI   SYI+ WMITIIG TL IPD+VMG+TF+AAG SVP+
Sbjct: 513 DCRQEKYRNWYPFTFCISMIWISFYSYIMVWMITIIGSTLGIPDTVMGLTFVAAGVSVPD 572

Query: 334 AVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLE 393
           A+SS+ V K+               FDIL+CLGLPW I+ ++   +PG + V + S GL 
Sbjct: 573 ALSSLAVIKEGLGDMAVSNAVGSNVFDILVCLGLPWFIQTAM--IQPGSH-VNVTSRGLT 629

Query: 394 YSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNVRTC 452
           YS +              FN +KLD   G   +  Y +F++LA+L ELNVF  +N  +C
Sbjct: 630 YSTLSLLSTVVFLVVATHFNGWKLDRRYGVVLMIWYLIFIVLASLYELNVFGQMNPPSC 688


>UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative -
           Nasonia vitripennis
          Length = 561

 Score =  243 bits (594), Expect = 9e-63
 Identities = 127/252 (50%), Positives = 155/252 (61%), Gaps = 11/252 (4%)

Query: 210 SKPNEMEIASPE--ENLYQP-TAEDNTDVE--DGSEN----SLWKWPSNKSCLAKITKIV 260
           SK NE    +P+  + +YQ        DVE  + SE     ++ +WP N     +   + 
Sbjct: 310 SKSNENFFTNPKAKDPIYQNGDCNGVMDVESLESSEELEIVNMTEWPDN--VWERCWWVF 367

Query: 261 TWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVM 320
           TWPI+ + L TIPDC +P  +NW+PLTFIMCIVWI  +SYIV W ITIIGDTLMIPDSVM
Sbjct: 368 TWPINAILLITIPDCRRPSLRNWYPLTFIMCIVWIALMSYIVGWDITIIGDTLMIPDSVM 427

Query: 321 GITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEP 380
           G+TFLAAG SVPEAVSSVIV  Q               FD+LLCLGLPW IKAS  P   
Sbjct: 428 GLTFLAAGMSVPEAVSSVIVTNQGHGTMGISNSIGSNVFDVLLCLGLPWFIKASFFPTAA 487

Query: 381 GHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIE 440
           G ++V+INS GL YS++               N++KLD  VG  CL MY++FL+ A LIE
Sbjct: 488 GEHFVQINSEGLIYSSVSLMSTLILLYTVLACNRYKLDKRVGFICLGMYSIFLVFAALIE 547

Query: 441 LNVFFPVNVRTC 452
           LNVFF VN  TC
Sbjct: 548 LNVFFVVNRPTC 559



 Score =  155 bits (377), Expect = 2e-36
 Identities = 67/117 (57%), Positives = 85/117 (72%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           M+ DV            PELF+N++GTF+TEGD+GVGTIVGSAVFNILAV ACCG+ A  
Sbjct: 154 MSKDVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNILAVPACCGLFASQ 213

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 117
           V+ LDWWP++RD LAYG+TV +LI  +HD  ++WYEAF+LV  Y  YI  M ++K I
Sbjct: 214 VLDLDWWPISRDSLAYGVTVLLLIFTLHDGRIEWYEAFILVLFYIFYILAMVFNKRI 270


>UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute
           carrier family 24, member 5; n=1; Apis mellifera|Rep:
           PREDICTED: similar to solute carrier family 24, member 5
           - Apis mellifera
          Length = 439

 Score =  241 bits (590), Expect = 3e-62
 Identities = 111/211 (52%), Positives = 141/211 (66%), Gaps = 2/211 (0%)

Query: 242 SLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYI 301
           ++  WP +K C  +I  ++TWPI+ V L TIPDC +   K+W+PLTFIMCI+WI S SYI
Sbjct: 229 NMTNWPKSK-C-ERIWWLITWPINFVLLITIPDCRRNTLKSWYPLTFIMCIIWIASTSYI 286

Query: 302 VAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDI 361
           V W+IT+IGDT  IPDS+MG+TFLAAG SVPEAVSSVIVA Q               FD+
Sbjct: 287 VGWVITVIGDTFRIPDSIMGLTFLAAGMSVPEAVSSVIVANQGHGAMGISNSIGSNVFDV 346

Query: 362 LLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAV 421
           LLCLGLPW +KA+L   EPG+++V INS GL YS+I                KFKL  +V
Sbjct: 347 LLCLGLPWFLKAALFSKEPGNHYVTINSQGLVYSSISLFSTLTVLYLSLLVGKFKLTRSV 406

Query: 422 GRACLAMYAMFLILATLIELNVFFPVNVRTC 452
           G  CL MY +FL+ A+++ELN+FF VN+  C
Sbjct: 407 GIICLTMYIIFLVFASILELNIFFMVNLPIC 437



 Score =  144 bits (349), Expect = 4e-33
 Identities = 63/120 (52%), Positives = 84/120 (70%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF+N++GTFITEGD+GVGTIVGSAVFNILAV ACCG+ A  
Sbjct: 82  VSEDVAGATIMATATSSPELFINIVGTFITEGDLGVGTIVGSAVFNILAVPACCGLFANQ 141

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L+ WP+TRD +AY ITV +LI  + D  ++WYEA +LV  Y +YI +M +D+ I  F
Sbjct: 142 ILNLEAWPVTRDTIAYAITVFLLILTLRDGRIEWYEALILVLSYFLYILVMCFDRNIHQF 201


>UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=3; Endopterygota|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 542

 Score =  219 bits (536), Expect = 9e-56
 Identities = 109/194 (56%), Positives = 125/194 (64%), Gaps = 2/194 (1%)

Query: 259 IVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDS 318
           I  WPI  +   TIPDC   R+     LTF +CI WIG  SY VA++IT++GDT+ IPDS
Sbjct: 349 ICRWPITFLLWATIPDCR--RYPKLRILTFFVCIFWIGITSYFVAFLITVVGDTMDIPDS 406

Query: 319 VMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPA 378
           VMG+TFLAAGTSVPEAVSS+IV  Q              TFDILLCLGLPWLIKA   PA
Sbjct: 407 VMGLTFLAAGTSVPEAVSSIIVTNQGHGEMGISNSIGSNTFDILLCLGLPWLIKALAFPA 466

Query: 379 EPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATL 438
            PG  WV +NS GL YSAI            FW NKFKLD  VG  C +MY  FL +++L
Sbjct: 467 IPGENWVALNSSGLTYSAISLLSTLCGLYIAFWSNKFKLDWKVGLTCTSMYIAFLTVSSL 526

Query: 439 IELNVFFPVNVRTC 452
           IELNVFF VN+ TC
Sbjct: 527 IELNVFFKVNLPTC 540



 Score =  134 bits (323), Expect = 6e-30
 Identities = 61/123 (49%), Positives = 79/123 (64%)

Query: 4   DVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP 63
           D+            PELF+N +GTFIT+GDIGVG +VGSAVFNILAV A CG+  G VV 
Sbjct: 158 DIAGATFMAAASSSPELFINCVGTFITKGDIGVGAVVGSAVFNILAVPAVCGLFGGQVVQ 217

Query: 64  LDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKG 123
           L WWP+TRD + YG+ V  LI +++D  V WYEA +LVS Y +YI  M  +  I  F   
Sbjct: 218 LRWWPVTRDSMMYGMAVIGLITVLNDGKVMWYEATILVSAYVLYITAMICNDSINRFMSR 277

Query: 124 SWK 126
           +++
Sbjct: 278 TFR 280


>UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca
           exchanger 5; n=1; Apis mellifera|Rep: PREDICTED: similar
           to Na-Ca exchanger 5 - Apis mellifera
          Length = 489

 Score =  193 bits (471), Expect = 7e-48
 Identities = 99/251 (39%), Positives = 139/251 (55%), Gaps = 7/251 (2%)

Query: 204 VNIDMDSKPNEMEIASPEENLYQPTAEDNTD--VEDGSENSLWKWPSNKSCLAKITKIVT 261
           V +D     N  E+   +  ++ P   +N +  ++      L+ WP  ++ + K   +  
Sbjct: 242 VVVDHRKNSNIQELEREQNRIHDPENVENFEKSIKRSIFEYLFTWPIERTIIEKCWFMFG 301

Query: 262 WPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMG 321
           WP+  +   TIPD +  R K+W+PLTFIMCI+WIG  SY+V+WM T+IGD + IPDS+MG
Sbjct: 302 WPLKFLLFITIPDPKIERLKHWYPLTFIMCIIWIGISSYLVSWMTTVIGDIIGIPDSIMG 361

Query: 322 ITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPG 381
           +TFLAAG ++PE  S VI+A+Q                DILLCLGLPW+IK  +      
Sbjct: 362 LTFLAAGGNMPEVASIVILARQGDGNMAMSNTLGANILDILLCLGLPWMIKCLMEKR--- 418

Query: 382 HYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIEL 441
             +V+I S  L+YS                  KFKL+  VG  CL +Y +FLI A LIEL
Sbjct: 419 --YVEIESGALKYSVFSTIICVIVLYTVIACFKFKLNKKVGIICLFLYMIFLIFAILIEL 476

Query: 442 NVFFPVNVRTC 452
           NVFF +N+  C
Sbjct: 477 NVFFIINLPMC 487



 Score =  112 bits (270), Expect = 2e-23
 Identities = 51/118 (43%), Positives = 73/118 (61%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELFVNVIGTF+TE D+G GT+VGSAVF+  A  AC  +    
Sbjct: 84  ISTDVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFDTFATPACGALMTFY 143

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 118
            + L+W  L+RDCL Y I+V  L+ I+ D  +QWYEA +L+ L+  Y+ +++  K I+
Sbjct: 144 AISLEWQVLSRDCLMYVISVGTLVIIMWDAKIQWYEAMILLILFCFYLILLFCGKHIR 201


>UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4;
           Caenorhabditis|Rep: Na/Ca,K-exchanger - Caenorhabditis
           elegans
          Length = 596

 Score =  193 bits (470), Expect = 9e-48
 Identities = 129/468 (27%), Positives = 228/468 (48%), Gaps = 29/468 (6%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PE F +VIG FI + ++G+GTIVGSA FNIL V A C + +  
Sbjct: 137 LSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCTLFSKS 196

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + +++L+    DE + + EA  + S+Y VY  +M ++  ++  
Sbjct: 197 ILDLTWWPLFRDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYIVYCTVMKFNGQLEQL 256

Query: 121 A-KGS----------WKWVSNMFKDNEEKQDAE-NGKDLKLSTHILKIDVPIEQRHQHNG 168
             KGS           K  +++  +N     A+  G +L+  +   +  VPI     H+G
Sbjct: 257 VKKGSDSEEASAHETQKLAADVPHNNNNNDLAQLEGSELRRRSSARRQSVPI----LHSG 312

Query: 169 NIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDM-DSKPNEMEIASPEENLYQP 227
            +  + + Q   + + +  + S++  +S      NVNI+  D     +  + P+    Q 
Sbjct: 313 TMFRNGIMQLMNQTLEQLPEDSEEDDSSR--SRSNVNIESHDMHRLNVNQSMPDRRSSQ- 369

Query: 228 TAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPL 286
             E  + +E+  E  L   WP  ++ + ++T ++  P+ +    TIPD  K   +  +P 
Sbjct: 370 IEEIKSLLEEQEEKPLDMTWP--ETWVKRLTYVLLAPVVIPMWVTIPDVRKSHNRGLYPA 427

Query: 287 TFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXX 346
           TFI+ I+WI   SY++ W    IG+T +IP  ++G+T LAAGTS+P+ ++SVIVA++   
Sbjct: 428 TFIISILWIAFFSYLMVWWANTIGETFVIPTEIIGLTILAAGTSIPDLITSVIVARKGLG 487

Query: 347 XXXXXXXXXXXTFDILLCLGLPW----LIKASLTPAEPGHYWVKINSMGLEYSAIXXXXX 402
                       FD+ + L +PW    LI+    P EP    + ++S GL  S       
Sbjct: 488 DMAVSSSVGSNIFDVCVGLPIPWLLYFLIEYIKHPNEPLSP-ISVSSKGLLCSVGMLFIM 546

Query: 403 XXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELN-VFFPVNV 449
                   + + +K++   G   +  Y  F + +  +E + +  P+N+
Sbjct: 547 LIVLVFAIFLSGWKMNKIFGILMIVSYVFFCVFSVSLETDKLVCPLNI 594



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 22/70 (31%), Positives = 31/70 (44%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           + ++ + L + D V G TF+AAG S PE  +SVI                  TF+IL  L
Sbjct: 128 LDVLTEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVL 187

Query: 366 GLPWLIKASL 375
               L   S+
Sbjct: 188 AFCTLFSKSI 197


>UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3); n=55;
           Eumetazoa|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) - Homo
           sapiens (Human)
          Length = 644

 Score =  176 bits (429), Expect = 9e-43
 Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)

Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
           D+ VN    D    E    +  EN      E+  + ED  E     + +    L  +   
Sbjct: 392 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 451

Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
            TWP+  V  FT+P+C KPR++ WF +TF    +WI + SY++ WM+TIIG TL IPD +
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511

Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
           MGITFLAAGTSVP+ ++S+IVA+Q               FDIL+ LGLPW ++      +
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 569

Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
            G Y +++NS GL YS                 NK++LD  +G  CL +Y +FL  + + 
Sbjct: 570 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 628

Query: 440 ELNVFFPVNVRTC 452
           E NVF  VN+  C
Sbjct: 629 EFNVFTFVNLPMC 641



 Score =  126 bits (303), Expect = 2e-27
 Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF +VIG FIT+GD+GVGTIVGSAVFNIL +   CG+ AG 
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           VV L  W L RD + Y ++V  LI  I+DE V W+E+ +LV +Y +YI IM Y+  I   
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 264

Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
            +   K   NM     +N E  D+ N
Sbjct: 265 FERRTKGAGNMVNGLANNAEIDDSSN 290


>UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchanger
           3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3).; n=2;
           Tetrapoda|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3). - Xenopus
           tropicalis
          Length = 524

 Score =  175 bits (426), Expect = 2e-42
 Identities = 95/256 (37%), Positives = 142/256 (55%), Gaps = 4/256 (1%)

Query: 194 SASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCL 253
           +++E   + N   D+    NE E  + E+N      E+  + ED ++     +       
Sbjct: 273 NSTERNGNSNRRDDVAEAGNETENEN-EDNENNENDEEEEEEEDDNDGPFTPFEVPSGNA 331

Query: 254 AKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTL 313
            K+  +VTWP+ L+  FT+P+C KPR++ WF +TF+   +WI +LSY++ WM+TIIG TL
Sbjct: 332 DKVKWMVTWPLCLLLYFTVPNCAKPRWEKWFMVTFVSSSMWIAALSYVMVWMVTIIGFTL 391

Query: 314 MIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKA 373
            IPD +MGITFLAAGTSVP+ ++S+IVA+Q               FDIL+ LGLPW ++ 
Sbjct: 392 GIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT 451

Query: 374 SLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFL 433
                + G Y VK   +  +   +              FNK++LD  +G ACL +Y +FL
Sbjct: 452 --LAVDYGSYNVKKCLLNAQL-LLLCIWLQRMQVCGVRFNKWRLDKKLGVACLLLYGVFL 508

Query: 434 ILATLIELNVFFPVNV 449
            L+ L E NVF  VN+
Sbjct: 509 CLSILTEFNVFTFVNL 524



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 40/90 (44%), Positives = 52/90 (57%), Gaps = 2/90 (2%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF +VIG FIT+GD+GVGTIVGSAVFNIL +   CG+ AG 
Sbjct: 52  LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 111

Query: 61  V--VPLDWWPLTRDCLAYGITVSILICIIH 88
           V  + L   P    CL Y   + I + +I+
Sbjct: 112 VRSMLLVSLPSPLQCLIYTHILYIYVFLIN 141



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 19/59 (32%), Positives = 28/59 (47%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           I + L + + V G TF+AAG+S PE  +SVI                   F+IL  +G+
Sbjct: 46  ISERLQLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 104


>UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium
           exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein
           CG1090); n=5; Bilateria|Rep: Probable
           sodium/potassium/calcium exchanger CG1090
           (Na(+)/K(+)/Ca(2+)- exchange protein CG1090) -
           Drosophila melanogaster (Fruit fly)
          Length = 642

 Score =  173 bits (420), Expect = 1e-41
 Identities = 83/199 (41%), Positives = 118/199 (59%), Gaps = 3/199 (1%)

Query: 254 AKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTL 313
           A ++  V +PIH +   T+PDC + +++NW+P TF+M +VWI   SY + WMIT+IG TL
Sbjct: 445 ALVSWYVVYPIHFLCKKTMPDCRQEQYRNWYPFTFLMSMVWISFYSYFMVWMITVIGSTL 504

Query: 314 MIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKA 373
            IPD+VMG+TF+AAG SVP+A+SS+ V K+               FDIL+CLGLPW I+ 
Sbjct: 505 AIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQT 564

Query: 374 SLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFL 433
           ++   +PG + V + S GL YS +               N +KLD  +G   +  Y  F+
Sbjct: 565 AI--IKPGSH-VNVISKGLAYSTLSLFSTVVFLILSTHLNGWKLDKRLGIILMVWYLFFI 621

Query: 434 ILATLIELNVFFPVNVRTC 452
            LA+L ELNVF  +N   C
Sbjct: 622 TLASLYELNVFGYMNPPEC 640



 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 39/123 (31%), Positives = 71/123 (57%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PEL   VIG F  + DIG+  ++GSAVFNI+ V + C + +G 
Sbjct: 160 LSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGT 219

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V  L+WWPL RDC  Y +++ +++ II ++ +  +E+ +++  Y  Y   ++++  ++ +
Sbjct: 220 VCQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVGYCVALHFNTELERW 279

Query: 121 AKG 123
           A G
Sbjct: 280 ALG 282


>UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchanger
           3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3).; n=1; Danio
           rerio|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3). - Danio rerio
          Length = 419

 Score =  167 bits (407), Expect = 4e-40
 Identities = 81/199 (40%), Positives = 118/199 (59%), Gaps = 3/199 (1%)

Query: 255 KITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLM 314
           K+  ++ WP+ ++  FT+P+   PR++ W+ ++FI   +WI   SYI+ WM+T+IG T+ 
Sbjct: 223 KLKWLLAWPLSMLLFFTVPNSANPRWERWYMVSFISSTIWIAFFSYIMVWMVTVIGYTMG 282

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
           IPD +MGITFLAAGTSVP+ ++S+IVA+Q               FDIL+ LGLPW ++  
Sbjct: 283 IPDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQ-- 340

Query: 375 LTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLI 434
            T A      + +NS GL +S                 N +KLD  +G ACL MYA+FL 
Sbjct: 341 -TLAINYGSTIHLNSKGLIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLC 399

Query: 435 LATLIELNVFFPVNVRTCK 453
            + LIE N+F  VN+ TC+
Sbjct: 400 FSILIEFNIFTFVNLPTCR 418



 Score =  124 bits (300), Expect = 4e-27
 Identities = 62/146 (42%), Positives = 83/146 (56%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF +VIG FIT+GD+GVGTIVGSAVFNIL +   CGI    
Sbjct: 28  LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGIFTAQ 87

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
            V L  W L RD   Y I V+ LI  I+DE V W+E+ +L+ LY VYI IM ++  + +F
Sbjct: 88  AVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVTWWESLILIVLYLVYILIMKFNSRVVHF 147

Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKD 146
            +   K  +N+        D ++G D
Sbjct: 148 IERRKKNPANLGNGTASNTDIDDGCD 173


>UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchanger
           5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5).; n=2;
           Tetrapoda|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5). - Xenopus
           tropicalis
          Length = 555

 Score =  158 bits (384), Expect = 2e-37
 Identities = 78/211 (36%), Positives = 118/211 (55%), Gaps = 5/211 (2%)

Query: 242 SLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYI 301
           S++  P N   L +I  +++ PI  +   T+PDC + R+KN F LTF+M  VWI +++YI
Sbjct: 348 SVFTMPEND--LKRIIWVLSLPIITLLYLTVPDCRRKRWKNLFILTFLMSAVWISAVTYI 405

Query: 302 VAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDI 361
           + WM+T++G+TL IPD+VMG+T LAAGTS+P+ V+SV+VA++                  
Sbjct: 406 LVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREAGKGDMAMSNIVGSNVFD 465

Query: 362 LLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAV 421
           +LCLG+PW IK            V++NS G+ Y+ I               N +KLD  +
Sbjct: 466 MLCLGVPWFIKTVFVDRSAP---VEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKL 522

Query: 422 GRACLAMYAMFLILATLIELNVFFPVNVRTC 452
           G  CL MY +F+ L+ L EL +     +  C
Sbjct: 523 GVMCLLMYLLFVTLSILYELGIIGNTAIVMC 553



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 9/121 (7%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAV-AACCGIGAG 59
           ++ DV            PE     +G F+T+GDIGV TIVGSAV+N+L + AACC +   
Sbjct: 65  LSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLS 124

Query: 60  MVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQN 119
           ++  L  W      + +          IH +    YE+  L+ +YG+YI  M +D  I  
Sbjct: 125 LLYMLKVWRYVCPWMYFS--------TIHWDAWNRYESASLILIYGIYIVTMCFDIRINQ 176

Query: 120 F 120
           +
Sbjct: 177 Y 177


>UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isoform
           1; n=2; Ostreococcus|Rep: Solute carrier family 24
           member 4, isoform 1 - Ostreococcus tauri
          Length = 545

 Score =  157 bits (381), Expect = 6e-37
 Identities = 113/440 (25%), Positives = 199/440 (45%), Gaps = 16/440 (3%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD--IGVGTIVGSAVFNILAVAACCGIGA 58
           +++DV            PEL  + +    +  D  IGVGTIVGSAVFNIL +     I A
Sbjct: 101 LSDDVAGATFMAAGSSAPELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIGATVIFA 160

Query: 59  GMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 118
           G  + LDW PL RDC  Y   +  +    +   V W+E  + V LY +YI  M+ ++   
Sbjct: 161 GETLKLDWRPLARDCTFYFAAIIGITLTFNGGVVNWWEGLIYVCLYMLYIAFMWKNQYFM 220

Query: 119 NFAKGSW-KWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVP--IEQRHQHNGNIKTSPL 175
                 + K++ +M     + +D      +++     + + P  I+Q+    G+I     
Sbjct: 221 ELLDRKFGKYMKSMTDSASDMEDGLGDGAVEMKDQASRRNEPGDIKQQLSVTGSIYVG-- 278

Query: 176 RQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDV 235
              A ++   ++D +    A   G+ + +    +         +   +   P  E + D 
Sbjct: 279 --FAAQRFKAALDKNKIKKALSVGELRAIRQQTEKVTWFHHHVNRPPSPRSPADEQDADE 336

Query: 236 EDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWI 295
           +D  E +   +   +    +   +++ P + V  FT+P C +  ++NW+ ++F + + +I
Sbjct: 337 DDDDEETN-PFAMPEDWKKRPMWVLSLPWYTVLTFTVPPCHRKEWENWYIVSFCVSVAYI 395

Query: 296 GSLS-YIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXX 354
           G +S Y+V W   I G  L IP  VMG T LAAGTS+P+A+SS+ VA+            
Sbjct: 396 GVISHYMVEWCARI-GCILSIPPVVMGTTVLAAGTSIPDALSSISVARDGFADMAVANAV 454

Query: 355 XXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNK 414
               FDI L LGLPW +   L+   P   ++ +++  L  S++               N 
Sbjct: 455 GSNVFDIWLGLGLPWTL--YLSWQNPS--YIVVSTAELLPSSLILLGVLFMYVSSVAMNG 510

Query: 415 FKLDAAVGRACLAMYAMFLI 434
           F++   +G+  +  YA++ +
Sbjct: 511 FQITRKMGQTYVGTYAVYAL 530


>UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=7;
           Murinae|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Mus
           musculus (Mouse)
          Length = 501

 Score =  154 bits (374), Expect = 4e-36
 Identities = 76/200 (38%), Positives = 112/200 (56%), Gaps = 4/200 (2%)

Query: 253 LAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDT 312
           L +I  +++ PI  +   T PDC +  +KN+F +TF M  +WI + +YI+ WM+T+ G+T
Sbjct: 304 LRRIFWVLSLPIITLLALTTPDCRRKFWKNYFVITFFMSALWISAFTYILVWMVTVTGET 363

Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           L IPD+VMG+T LAAGTS+P+ V+SV+VA++               FD +LCLGLPW IK
Sbjct: 364 LGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFD-MLCLGLPWFIK 422

Query: 373 ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMF 432
            + T A      +++NS GL Y  I              FN +KLD  +G  CL +Y   
Sbjct: 423 TAFTNASAP---IEVNSKGLTYITISLNISILFLFLAVHFNGWKLDRKLGVVCLVLYLGL 479

Query: 433 LILATLIELNVFFPVNVRTC 452
             L+ L E+ +     +R C
Sbjct: 480 ATLSVLYEIGIIGNNRIRGC 499



 Score =  109 bits (263), Expect = 1e-22
 Identities = 46/117 (39%), Positives = 69/117 (58%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PEL    +G FIT+GDIG+ TI+GSA++N+L + A CG+ + M
Sbjct: 104 LSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNM 163

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 117
           V  L  WPL RDC  Y ++V  +  II D  + WYE   L+ +YG+Y+ ++ +D  I
Sbjct: 164 VSTLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTI 220



 Score = 34.7 bits (76), Expect = 5.2
 Identities = 15/34 (44%), Positives = 23/34 (67%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
           + II D+L +   V G TF+AAG+S PE V++ +
Sbjct: 95  LEIISDSLGLSQDVAGATFMAAGSSAPELVTAFL 128


>UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 429

 Score =  151 bits (367), Expect = 3e-35
 Identities = 81/195 (41%), Positives = 115/195 (58%), Gaps = 7/195 (3%)

Query: 247 PSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMI 306
           P   +C A+   + T P  LVF  TIPDC K  ++ ++ +TF + ++W+  LSY + WM+
Sbjct: 230 PPEGAC-ARALWVFTLPSILVFYVTIPDCRKKTWRKFYLVTFTVAVIWMAVLSYFLVWMV 288

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
            IIG T  IP+ VMG+TFLAAG+S+P+A++S++VAKQ               FD +LCLG
Sbjct: 289 AIIGYTYTIPECVMGMTFLAAGSSLPDAIASLVVAKQGSGDMAVSNCIGSNVFD-MLCLG 347

Query: 367 LPWLIK-ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRAC 425
           +PWLIK A L P +P    V I S  + +++               FNK+KL+  VG A 
Sbjct: 348 IPWLIKSAFLQPGKP----VVIQSENIFFTSAMLIGSIAVTFLLIQFNKWKLNVKVGIAF 403

Query: 426 LAMYAMFLILATLIE 440
           L MY +FLI+AT IE
Sbjct: 404 LIMYFLFLIVATYIE 418



 Score =  110 bits (265), Expect = 6e-23
 Identities = 48/119 (40%), Positives = 70/119 (58%)

Query: 4   DVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP 63
           DV            P LF+ +I  F TEGDIG+GTIVGS +FN L + A C IG+G+ + 
Sbjct: 62  DVAGATFMAVGSSAPTLFIAIISIFFTEGDIGLGTIVGSTIFNTLFIIALCAIGSGVTLQ 121

Query: 64  LDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 122
           L  +P++RD   Y  +V +L+  I+D  V WYE  + V +Y +YI IMY++  ++   K
Sbjct: 122 LACYPISRDSTVYVASVIVLMVSIYDNKVYWYEGLIFVIVYAIYIVIMYFNDQVEGLCK 180


>UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=20;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Homo
           sapiens (Human)
          Length = 500

 Score =  151 bits (366), Expect = 4e-35
 Identities = 76/200 (38%), Positives = 109/200 (54%), Gaps = 4/200 (2%)

Query: 253 LAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDT 312
           L +I  +++ PI  +   T PDC K  +KN+F +TF M  +WI + +YI+ WM+TI G+T
Sbjct: 303 LKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGET 362

Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           L IPD+VMG+T LAAGTS+P+ ++SV+VA++               FD +LCLG+PW IK
Sbjct: 363 LEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFD-MLCLGIPWFIK 421

Query: 373 ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMF 432
            +      G    ++NS GL Y  I              FN +KLD  +G  CL  Y   
Sbjct: 422 TAFI---NGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGL 478

Query: 433 LILATLIELNVFFPVNVRTC 452
             L+ L EL +     +R C
Sbjct: 479 ATLSVLYELGIIGNNKIRGC 498



 Score =  114 bits (274), Expect = 5e-24
 Identities = 48/120 (40%), Positives = 73/120 (60%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PEL    +G FIT+GDIG+ TI+GSA++N+L + A CG+ +  
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNT 163

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V  L  WPL RDC AY I+ + ++ II+D  V WYE  LL+ +YG+Y+ ++ +D  I  +
Sbjct: 164 VSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQY 223


>UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=2; Culicidae|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 549

 Score =  151 bits (365), Expect = 5e-35
 Identities = 81/228 (35%), Positives = 122/228 (53%), Gaps = 5/228 (2%)

Query: 223 NLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRF-K 281
           +L  P+     D E+    SLWK  + ++ L  I  + +WPI  V  FTIP+   P + +
Sbjct: 324 DLQIPSRHVLPDTEEYPPMSLWKI-ARETKLRTIWWLYSWPIRFVLTFTIPN---PTYMR 379

Query: 282 NWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA 341
            W+PLTFIMCI++IG  S++  WM++IIG TL IPD VMG+TFLA G  +PEA+S+V++ 
Sbjct: 380 RWYPLTFIMCIIFIGLTSFLTFWMMSIIGYTLGIPDGVMGLTFLAMGGCMPEAISAVLII 439

Query: 342 KQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXX 401
           +               +  I+  LGLPW I+     A   + +V I S G++YS I    
Sbjct: 440 RTGNGAVGVSNALGANSLSIVFSLGLPWFIRTVADGASTTNAYVIIASHGMQYSIIALLF 499

Query: 402 XXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNV 449
                    +  K+KL   +G A +  Y + +    L EL++FFP  +
Sbjct: 500 AVGSLYVVIYIGKYKLRRRIGVALIFCYVILVTFMLLNELDIFFPSGI 547



 Score =  121 bits (291), Expect = 5e-26
 Identities = 54/145 (37%), Positives = 77/145 (53%), Gaps = 4/145 (2%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +T DV            PE F N I TFI + D+G+GTI+GS +FN L VA   G+    
Sbjct: 141 LTQDVAAATFMAIAGTIPEFFTNTISTFIADSDMGIGTIMGSLLFNTLGVACLAGLACKK 200

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
            V LDWWP+TRDC+ +   +S+L+    D  + WYE+ + V L   Y  +M+ +KPI   
Sbjct: 201 PVQLDWWPITRDCIVFAFHISVLVGFAWDGRIYWYESMVFVILLFTYFVVMFQNKPIMKL 260

Query: 121 AKG----SWKWVSNMFKDNEEKQDA 141
           AK      W   + + +D EE + A
Sbjct: 261 AKKYIEVKWNLCARVIRDIEETEQA 285


>UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=1; Aedes aegypti|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 520

 Score =  150 bits (363), Expect = 9e-35
 Identities = 81/214 (37%), Positives = 111/214 (51%), Gaps = 3/214 (1%)

Query: 233 TDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCI 292
           +D  D S   L K  S  S L       TWP  ++   TIPD  K R    +PLTF MCI
Sbjct: 305 SDQSDDSRMHLLKI-SKDSWLGVFWWFYTWPFRVIVNVTIPDPRKHR--KLYPLTFFMCI 361

Query: 293 VWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXX 352
            WIG  +Y+V WM+TIIG T  +P++VMG+TFLA G  +PEAVS++ V ++         
Sbjct: 362 AWIGGTAYMVFWMMTIIGSTFDVPETVMGLTFLAFGGCMPEAVSAITVIRKGNGSMGVSN 421

Query: 353 XXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWF 412
                T  IL  LGLPW I+  +        +++INS G++YS +             + 
Sbjct: 422 SLGANTLAILFSLGLPWFIRNMMEGGATTGAYIEINSYGMQYSVLALFLAVGILYLVLYL 481

Query: 413 NKFKLDAAVGRACLAMYAMFLILATLIELNVFFP 446
           +KF L   VG A L  Y + +    L+EL+VFFP
Sbjct: 482 SKFTLRKLVGLALLIAYLIIVSFMILVELDVFFP 515



 Score =  106 bits (254), Expect = 1e-21
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 4/158 (2%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PE F N I T + + D+G+GTI+GS +FN L VAA  G+    
Sbjct: 120 LSEDVAAATFMATATSMPEFFTNTISTLVVDSDMGLGTIMGSMLFNTLGVAALVGLLTKS 179

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
            V LDWWPLTRD +   I+ S L+  + DE V WYE+ + V LY +Y  +M+ +  ++  
Sbjct: 180 HVKLDWWPLTRDSIIVIISTSSLVSCLWDERVYWYESLVFVVLYVLYFLVMFQNDRMKRI 239

Query: 121 A----KGSWKWVSNMFKDNEEKQDAENGKDLKLSTHIL 154
           A    +  W     + K + ++  +E     K S  +L
Sbjct: 240 AVSLIEDRWNLCRRLEKKSSDEPQSEYKNHRKYSIAVL 277


>UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchanger
           5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5).; n=1; Takifugu
           rubripes|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5). - Takifugu rubripes
          Length = 473

 Score =  149 bits (362), Expect = 1e-34
 Identities = 74/194 (38%), Positives = 108/194 (55%), Gaps = 4/194 (2%)

Query: 250 KSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITII 309
           +S L +I  +++ PI  +   T PDC +  +K WF +TF M  VWI   +YI+ WM+T++
Sbjct: 282 ESDLKRIFWVLSLPIITLLFLTTPDCRRSFWKKWFMVTFFMSAVWISGFTYILVWMVTVV 341

Query: 310 GDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPW 369
           G+TL IPD+VMG+T LAAGTS+P+ V+SV+VA++               FD +LCLGLPW
Sbjct: 342 GETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFD-MLCLGLPW 400

Query: 370 LIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMY 429
            IK +          V++NS GL + +                N +KLD  +G  CL  Y
Sbjct: 401 FIKTAFVDTNNP---VEVNSSGLVFISSTLLLSIVFLFVAIHINGWKLDWKLGIVCLICY 457

Query: 430 AMFLILATLIELNV 443
            +F  L+ L EL +
Sbjct: 458 ILFATLSILYELGI 471



 Score =  118 bits (283), Expect = 4e-25
 Identities = 54/120 (45%), Positives = 74/120 (61%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PEL    +G F+T+GDIGV TIVGSAV+N+L + A CG+   +
Sbjct: 60  LSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGLLTTV 119

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
              L  WPL RDCLAYGI+V+ +I II+D  V WY+A  L+ +Y VYI ++ +D  I  F
Sbjct: 120 AGRLTCWPLFRDCLAYGISVTAVIAIIYDNKVYWYDAASLLLVYMVYIVVLCFDLRISEF 179


>UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute
           carrier family 24, member 5; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to solute carrier
           family 24, member 5 - Tribolium castaneum
          Length = 488

 Score =  145 bits (352), Expect = 2e-33
 Identities = 87/262 (33%), Positives = 136/262 (51%), Gaps = 9/262 (3%)

Query: 183 ILESVDVSDKVSASEEGK---DKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGS 239
           +L  +   +KVS  E+G     + ++I + S       A  + N Y  T        +  
Sbjct: 221 VLRLIKRGNKVSDCEKGAAATPRRMSIAVVSSYGSY--AEEQINKYTETKNIAETATEEE 278

Query: 240 ENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLS 299
             SL++ P   S   K     +WPI  +   T+PD    R+   FP+TFI+CI WIGS S
Sbjct: 279 SFSLFRMPKG-SIWKKAFFYYSWPIKFILFCTVPD--PMRYPKLFPVTFILCIFWIGSNS 335

Query: 300 YIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTF 359
           YIV+WMI IIG+   IPD+V+G+TFLAAG  +PEA+S  I++++              T 
Sbjct: 336 YIVSWMIAIIGNMFKIPDAVLGLTFLAAGGCLPEAISITIMSRRGEGSMGVSNSLGANTM 395

Query: 360 DILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDA 419
           +ILL LG+PW +K ++        +++I+S  LE++              F+FNKF++  
Sbjct: 396 NILLSLGMPWFLK-TIVMGTDEQAFIRISSGSLEFTISALIPVAIILYLTFYFNKFQMCR 454

Query: 420 AVGRACLAMYAMFLILATLIEL 441
            VG   +++Y + +ILA L E+
Sbjct: 455 KVGFILISVYTVCIILAILGEM 476



 Score =  121 bits (291), Expect = 5e-26
 Identities = 51/120 (42%), Positives = 76/120 (63%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PELFVN+IGTFITE DIG+GT+VGS++FN L VA+   + A  
Sbjct: 101 LSHDVAAATFMSVATSTPELFVNIIGTFITESDIGIGTVVGSSLFNTLGVASLGSLAAST 160

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
            V L WWP++RD + Y +++ +L+ I  D Y+ WYE  +L  +Y +Y  +M+ +  I NF
Sbjct: 161 PVQLHWWPISRDVIIYILSILLLVGITWDGYIYWYEGLVLFLVYFIYFTVMFQNVRISNF 220


>UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000012714 - Anopheles gambiae
           str. PEST
          Length = 386

 Score =  142 bits (343), Expect = 2e-32
 Identities = 71/192 (36%), Positives = 101/192 (52%), Gaps = 2/192 (1%)

Query: 259 IVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDS 318
           I TWP   V   TIPD    RF+  +PLTF+ CI WIG  +Y+V WMI++IG+T  IPD+
Sbjct: 196 IFTWPYRFVVFLTIPD--PLRFRKLYPLTFVCCIGWIGVSAYLVFWMISVIGNTFGIPDT 253

Query: 319 VMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPA 378
           VMG+TFLA G  +PEA S++ + ++              T  IL  LGLPW I+  +   
Sbjct: 254 VMGMTFLAFGGCMPEAASAITLIRRGNGAMGVSNSLGANTLAILFSLGLPWFIRTMIDGG 313

Query: 379 EPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATL 438
                ++ I S G++YS +             +  K+ L   VG A    Y + +    L
Sbjct: 314 PSTGAYIAIQSYGIQYSVLALFGAIFTLYAVLYVAKYTLRKMVGLALAVGYLVIVTFMIL 373

Query: 439 IELNVFFPVNVR 450
           +EL+VFFP + R
Sbjct: 374 VELDVFFPADNR 385



 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 24/56 (42%), Positives = 30/56 (53%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 56
           ++ DV            PE F N I T   + DIGVGTI+GS +FN L VAA  G+
Sbjct: 56  LSQDVAAATFMATATSMPEFFTNTISTLAVDSDIGVGTIMGSMLFNTLGVAALVGL 111


>UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 346

 Score =  140 bits (338), Expect = 9e-32
 Identities = 97/354 (27%), Positives = 170/354 (48%), Gaps = 20/354 (5%)

Query: 96  EAFLLVSLYGVYICIMYYDKPIQNF-AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHIL 154
           ++  L++LY  Y  +M++++PI+   +K +    ++  KD   +Q  +NG          
Sbjct: 2   DSVTLLALYVSYCILMFFNRPIEQMVSKITPGCCTHKQKDITVEQPIQNGH--------A 53

Query: 155 KIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNE 214
           + D     R     ++  SP+R     ++   V   +      +G + N +  + S P+ 
Sbjct: 54  RGDEMESTRLLDGSDVDCSPVRHQMNFQVTTGVHDPNGGDDEGDGGENNNDKAVRSDPHR 113

Query: 215 MEIASPEENLYQPTAEDN-TDVEDGSE-NSLWKWPSNKSCLAKITKIVTWPIHLVFLFTI 272
                 E N  + T  DN  D E+ +E  S ++ P     + +  +++ +PI  VF  +I
Sbjct: 114 ----DLERNDRRNTDNDNFVDDENETEPGSPFRLPEKG--VNRYAQMLAFPIIAVFFISI 167

Query: 273 PDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVP 332
           PDC + R+K  + LTFI  ++WIG L+YI+ WM+T  GDT+ IPD+VMG+T LAAG S P
Sbjct: 168 PDCRRKRWKRCYVLTFICSLLWIGFLTYILVWMVTAFGDTIGIPDTVMGLTLLAAGASTP 227

Query: 333 EAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGL 392
           + + S+I A+                FDIL+ LGLPW I+  +         V + S  +
Sbjct: 228 DTMLSIIAARGGYGDMAISHSIGSNLFDILVGLGLPWFIQTVIIDHRS---TVTVYSGAI 284

Query: 393 EYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFP 446
            Y ++                +F+L   +G   +  + +F++++ L ELN+  P
Sbjct: 285 SYISMLLLLTVVIAVVLINVCRFRLGKTLGVFFIIFFVIFIMVSILFELNLIVP 338


>UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 639

 Score =  138 bits (335), Expect = 2e-31
 Identities = 93/300 (31%), Positives = 145/300 (48%), Gaps = 29/300 (9%)

Query: 162 QRHQHNGNIK-TSPLRQDAKEKILE------SVDVSDKVSASEEGKDKNVNIDMDSKP-N 213
           +R  HN   K T P   + + K+ E      +    DK+    E +   +N   +    N
Sbjct: 310 KRKGHNERRKETEPKESEKRNKLTELDGATHNKQNEDKIDEKNENEHNKLNEHCEGDSHN 369

Query: 214 EMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSN-----KSCL----AKITKIVTW-- 262
           E ++    E + Q   ED T  + G+  S    PS+      SC     +  +K + W  
Sbjct: 370 EGKMDKENERIEQK--EDAT--KSGASGSHQNTPSHIHGFKPSCPFTPPSTFSKRIVWIF 425

Query: 263 --PIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVM 320
             P+HL F  T+PDC   +++ W+P TF + I+W+ +LSY++ W ++IIG+T  IP+ +M
Sbjct: 426 MLPVHLAFYVTMPDCRVKKWEAWYPATFALSIIWMAALSYVLVWTVSIIGETFSIPEYIM 485

Query: 321 GITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEP 380
           G+T LAAG+SVP+ +SS+IVAK                FD+ LCLGLPWL+  + T   P
Sbjct: 486 GLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDV-LCLGLPWLL--ATTAVHP 542

Query: 381 GHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIE 440
               V I+S  + Y ++               N ++LD  +G      YA FL  A ++E
Sbjct: 543 NSV-VLIHSGHIVYVSMCLFGTVLTIVSAIHLNGWRLDRRLGVILFIAYAFFLTSAVILE 601



 Score =  106 bits (255), Expect = 1e-21
 Identities = 48/133 (36%), Positives = 77/133 (57%)

Query: 4   DVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP 63
           DV            P LF+ +   F+ EGDIG+GTI+GS++FNIL + A CG+ +GMV+ 
Sbjct: 88  DVAGATFMAAGSSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNILFITAICGLFSGMVIS 147

Query: 64  LDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKG 123
           L  WP+ RD   Y + +  L+ +IHD  + +YEA +   LY  YI IM ++  ++N  + 
Sbjct: 148 LHTWPIVRDSCVYVVNLVGLLIVIHDNVIHFYEALIFPVLYTGYILIMVFNTRLENAFES 207

Query: 124 SWKWVSNMFKDNE 136
           +++   ++ K  E
Sbjct: 208 AFETCCDINKGME 220


>UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF15008, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 557

 Score =  136 bits (330), Expect = 9e-31
 Identities = 57/122 (46%), Positives = 81/122 (66%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FITEGD+GVGTIVGSAVFNIL +   CGI AG 
Sbjct: 29  LSQDVAGATFMAAGSSAPELFTSLIGVFITEGDVGVGTIVGSAVFNILVIIGICGIFAGQ 88

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
            + L WWPL RD + Y +++ +LI +I+DE V W+E  +L+S+YG+YI IM +++ +   
Sbjct: 89  PISLSWWPLFRDAVFYILSILVLILVIYDEKVMWWETIILISMYGIYIIIMKFNRSLHGL 148

Query: 121 AK 122
            +
Sbjct: 149 VE 150



 Score =  126 bits (304), Expect = 1e-27
 Identities = 59/139 (42%), Positives = 87/139 (62%), Gaps = 3/139 (2%)

Query: 259 IVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDS 318
           +++WP+ ++   T+P+C  P+++ W+ LTF+   +WI   SY++ WM+TII  TL IP+ 
Sbjct: 326 LLSWPVSVLLHCTVPNCSLPQWERWYLLTFLTSTLWIALFSYLMVWMVTIISFTLGIPEV 385

Query: 319 VMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPA 378
           +MGITFLAAGTSVP+ ++S+IVA+Q               FD+LL LG PW ++  +   
Sbjct: 386 IMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDVLLGLGFPWALRTLI--V 443

Query: 379 EPGHYWVKINSMGLEYSAI 397
             G   V INS GL YS I
Sbjct: 444 SYGSV-VTINSKGLVYSVI 461


>UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila
           melanogaster|Rep: CG17167-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 441

 Score =  134 bits (325), Expect = 3e-30
 Identities = 74/218 (33%), Positives = 115/218 (52%), Gaps = 8/218 (3%)

Query: 231 DNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIM 290
           D  DV D    S++ +P + S   +   I  +PI +     IP   K  ++  +PL+FIM
Sbjct: 225 DEDDVADVVPGSIYAYPRDASGWMQFWWIFVFPIKVTLSLLIPHPMK--YRRLYPLSFIM 282

Query: 291 CIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXX 350
           CI+ IG  +Y++ WM+T  G  + +P  VMG+TFLAAG+++PEAVSS+I  +        
Sbjct: 283 CILCIGGNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGV 342

Query: 351 XXXXXXXTFDILLCLGLPWLIKASL--TPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXX 408
                  +  ILL LG+PW IK  +     EP     ++ + G+EY+ +           
Sbjct: 343 SNSLGANSLAILLSLGVPWFIKNCIHYGTGEP----QQVGTQGIEYNILILIISTMALFI 398

Query: 409 XFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFP 446
              F+ ++L   VG A   +Y +F++L  LIE+NVFFP
Sbjct: 399 ILSFSGYRLTKRVGVALFTVYGVFIVLQILIEMNVFFP 436



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 22/56 (39%), Positives = 29/56 (51%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 56
           ++ DV            PE F N I T I E D+G+GTI+GS +FN L VA    +
Sbjct: 118 LSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAAL 173


>UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependent
           Na,Ca exchanger; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to K-dependent Na,Ca exchanger -
           Strongylocentrotus purpuratus
          Length = 259

 Score =  130 bits (315), Expect = 6e-29
 Identities = 72/212 (33%), Positives = 110/212 (51%), Gaps = 6/212 (2%)

Query: 233 TDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPR-FKNWFPLTFIMC 291
           TD    SE     +    S   ++   V  P+ L+   T+PDC KP  ++  +  TF + 
Sbjct: 39  TDHPPLSEQDSHVFSPPSSWFFRVLWFVGLPVILIMFLTVPDCRKPGLWRRLYFFTFFIS 98

Query: 292 IVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXX 351
            VW+  L+Y++ WMI +IG TL IPD+VMGI+ LAAGTSVP+A++SV+VA+         
Sbjct: 99  TVWLAGLAYVLYWMIVVIGYTLDIPDTVMGISLLAAGTSVPDAIASVLVARDGYGDMALS 158

Query: 352 XXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFW 411
                  F++ +CLGL W I   L    P    V+I S GL ++ +              
Sbjct: 159 NIVGSNIFEVFICLGLLWFI-YGLVYQRP----VEIASEGLLFTTVALLVTVAFILLAIH 213

Query: 412 FNKFKLDAAVGRACLAMYAMFLILATLIELNV 443
            N +KLD  +G  C+ +Y +F+ +A + EL +
Sbjct: 214 LNGWKLDKKMGVLCMCVYLIFITIAIVWELGL 245


>UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila
           melanogaster|Rep: CG12061-PA.3 - Drosophila melanogaster
           (Fruit fly)
          Length = 353

 Score =  126 bits (304), Expect = 1e-27
 Identities = 59/122 (48%), Positives = 75/122 (61%), Gaps = 1/122 (0%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           MT DV            PELFVN +GTF+T GDIG+GTIVGS+VFNIL +A  CGI    
Sbjct: 1   MTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-Q 59

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
              LDWWP+TRD   Y I ++ L  ++ D  V WYEAF L+ LY  Y+  + +D+ IQN 
Sbjct: 60  PTKLDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNL 119

Query: 121 AK 122
            +
Sbjct: 120 VR 121



 Score =  117 bits (282), Expect = 6e-25
 Identities = 61/167 (36%), Positives = 89/167 (53%), Gaps = 5/167 (2%)

Query: 275 CEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEA 334
           C  P  ++ F L+ I  I+WI  +SY++ W +TI+G  L IPD++MG+T LAAGTSVPE 
Sbjct: 180 CTVPSARSIFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVPEV 239

Query: 335 VSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEY 394
            SS IV+K+              TFDIL+CLGLPWL+K  +   +     + I+S  L  
Sbjct: 240 ASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLKILIYQQK-----IDIDSTALTI 294

Query: 395 SAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIEL 441
           +                  +F +   VG   +  YA+FLI+A  +E+
Sbjct: 295 TTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACTLEI 341


>UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx30C
           (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C); n=7;
           Diptera|Rep: Sodium/potassium/calcium exchanger Nckx30C
           (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) -
           Drosophila melanogaster (Fruit fly)
          Length = 888

 Score =  125 bits (302), Expect = 2e-27
 Identities = 70/233 (30%), Positives = 117/233 (50%), Gaps = 14/233 (6%)

Query: 220 PEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPR 279
           P  N+   T +   ++ED  E     WP   +   ++T ++  P+ +    T+PD   PR
Sbjct: 668 PNGNI-DTTLDSAPEIEDEPEPLSMAWPD--TARKRLTYVLVAPLLVPMWLTLPDTRTPR 724

Query: 280 FKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
            K +FP+TFI  IVWI + SY++ W   + GDT  IP  VMG+TFLAAGTS+P+ ++SVI
Sbjct: 725 GKRFFPVTFIGSIVWIAAFSYLMVWWANVAGDTARIPPEVMGLTFLAAGTSIPDLITSVI 784

Query: 340 VAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXX 399
           VA++               FD+ + L +PWL+   +  A      V++NS+G+  S    
Sbjct: 785 VARKGFGDMAVSSSVGSNIFDVTVGLPIPWLLYGIIYGAP-----VEVNSVGMVCSITIL 839

Query: 400 XXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNVRTC 452
                         +++++  +G      + MFL+    + +++ F  +V TC
Sbjct: 840 FMMLVFVVMSIACFRWRMNKGLG------FTMFLLYFAFVAVSLMFEYDVITC 886



 Score =  110 bits (265), Expect = 6e-23
 Identities = 49/122 (40%), Positives = 72/122 (59%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +T+DV            PELF +VIG F++  D+G+GTIVGSAVFNIL V   C + +  
Sbjct: 368 ITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKT 427

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V+ L WWPL RDC  Y I++ +LI    D  + W+EA +L ++Y  Y+  M ++  ++  
Sbjct: 428 VLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETC 487

Query: 121 AK 122
            K
Sbjct: 488 VK 489



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 21/62 (33%), Positives = 29/62 (46%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           + +I + L I D V G TF+AAG S PE  +SVI                   F+IL  +
Sbjct: 359 LDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVI 418

Query: 366 GL 367
           G+
Sbjct: 419 GM 420


>UniRef50_Q91WD8 Cluster: Solute carrier family 24
            (Sodium/potassium/calcium exchanger), member 1; n=2;
            Eutheria|Rep: Solute carrier family 24
            (Sodium/potassium/calcium exchanger), member 1 - Mus
            musculus (Mouse)
          Length = 1130

 Score =  121 bits (292), Expect = 3e-26
 Identities = 80/317 (25%), Positives = 153/317 (48%), Gaps = 11/317 (3%)

Query: 136  EEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILES-VDVSDKVS 194
            E K++ E   + +      + +   E + +H G  +T P   + K+   E+  +  D+  
Sbjct: 822  EGKEEQEGETEAESKEVEQERETEAEGKDKHEGQGETQPDDTEVKDGEGETEANAEDQCE 881

Query: 195  ASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCL 253
            A++  K  +   + D   +E E    EE+  +   ED  + E+ +E  L  +WP ++   
Sbjct: 882  ATQGEKGADGGGESDGGDSEEE--EDEEDEEEEEEEDEEEEEEENEEPLSLEWPDSRQKQ 939

Query: 254  AKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTL 313
            A    ++  PI      TIPD  +   + +F +TF+  I+WI   SY++ W    +G+T+
Sbjct: 940  AIYLFLL--PIVFPLWLTIPDVRRQESRKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 997

Query: 314  MIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKA 373
             I + +MG+T LAAGTS+P+ ++SVIVA++               FDI + L +PWL+ +
Sbjct: 998  GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1057

Query: 374  SLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFL 433
             +   +P    V ++S GL  + +                K++++  +G     +Y +FL
Sbjct: 1058 LINALQP----VPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLLYFVFL 1113

Query: 434  ILATLIELNVF-FPVNV 449
            +++ ++E  +   PV+V
Sbjct: 1114 VISVMLEDRIISCPVSV 1130



 Score =  111 bits (266), Expect = 5e-23
 Identities = 64/226 (28%), Positives = 117/226 (51%), Gaps = 4/226 (1%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 457 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSRE 516

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + +S+LI    D ++ W+E+ LL+  Y +Y+  M ++K I+ +
Sbjct: 517 ILNLTWWPLFRDVSFYILDLSMLIVFFLDSFIAWWESLLLLLAYALYVFTMKWNKQIELW 576

Query: 121 AKG--SWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVP-IEQRHQHNGNIKTSPLRQ 177
            K   S + V+ +    +  + +E+  +        K+ +P +  R   + ++  S +R 
Sbjct: 577 VKEQLSRRPVAKVMALGDLSKPSEDAVEENEQQDSKKLKLPSVLTRGSSSASLHNSIIRN 636

Query: 178 DAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEEN 223
                +L S+D   +   S++ K +++N +          +SP+E+
Sbjct: 637 TIYHLMLHSLDPLGEARPSKD-KQESLNQEARVLSQTKAESSPDED 681



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 1/83 (1%)

Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           F + ++   + I    Y V   + +I   L I + V G TF+AAG S PE  +S+I    
Sbjct: 427 FGMMYVFVALAIVCDEYFVP-ALGVITHKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 485

Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
                          F+IL  +G
Sbjct: 486 SHSNVGIGTIVGSAVFNILFVIG 508


>UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:
           Slc24a2 protein - Mus musculus (Mouse)
          Length = 711

 Score =  121 bits (292), Expect = 3e-26
 Identities = 69/224 (30%), Positives = 113/224 (50%), Gaps = 8/224 (3%)

Query: 227 PTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPL 286
           P A +  + ED    SL  WP+N    A  T ++ +PI      T+PD  KP  + +FP+
Sbjct: 495 PKATETAEEEDDQPLSL-SWPTNTRKQA--TFLIVFPIVFPLWITLPDVRKPASRKFFPI 551

Query: 287 TFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXX 346
           TF   I WI   SY++ W    +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++   
Sbjct: 552 TFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLG 611

Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXX 406
                       FDI + L LPWL+   +    P    V ++S GL  + +         
Sbjct: 612 DMAVSSSVGSNIFDITVGLPLPWLLYTIIHRFSP----VTVSSNGLFCAIVLLFIMLLFV 667

Query: 407 XXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFF-PVNV 449
                  K++++  +G     +Y +FL+++ L+E  V   PV++
Sbjct: 668 ILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDKVLVCPVSI 711



 Score =  101 bits (242), Expect = 4e-20
 Identities = 44/122 (36%), Positives = 70/122 (57%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PELF ++IG FI   ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 171 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 230

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + + +LI    D  + W+E+ LL++ Y  Y+  M ++  ++ +
Sbjct: 231 ILNLTWWPLFRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVVFMKFNVQVERW 290

Query: 121 AK 122
            K
Sbjct: 291 VK 292



 Score = 38.7 bits (86), Expect = 0.32
 Identities = 21/62 (33%), Positives = 30/62 (48%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           +T+I + L I D V G TF+AAG S PE  +S+I                   F+IL  +
Sbjct: 162 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 221

Query: 366 GL 367
           G+
Sbjct: 222 GM 223


>UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 -
           Morone saxatilis (Striped bass)
          Length = 749

 Score =  120 bits (288), Expect = 1e-25
 Identities = 75/266 (28%), Positives = 130/266 (48%), Gaps = 9/266 (3%)

Query: 185 ESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLW 244
           E+ D     S   E  D + + D D   ++ +  + EE   +   E+  + E+    SL 
Sbjct: 492 ENSDEGSSDSGEGEDDDDDDDDDDDDDDDDDDDGNKEEE-GKGEGEEEEEEEENEPLSL- 549

Query: 245 KWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAW 304
           +WP  +    ++T ++  PI      T+PD      + +F +TFI  I+WIG  SY++ W
Sbjct: 550 EWPETRR--KQVTYLLLLPIVFPLWLTLPDVRNLASRKYFVITFIGSILWIGVFSYMMVW 607

Query: 305 MITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLC 364
               +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++               FDI + 
Sbjct: 608 WAHQVGETVGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITIG 667

Query: 365 LGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRA 424
           L +PWLI   L   EP    V ++S GL  + +                ++K+   +G  
Sbjct: 668 LPVPWLIYTLLHNGEP----VAVSSNGLFCAIVLLFLMLLFVIISIAACRWKMSRMLGLT 723

Query: 425 CLAMYAMFLILATLIELNVF-FPVNV 449
             A+Y +FL+L+ ++E  +   PV++
Sbjct: 724 MFALYFVFLVLSVMLEDRILTCPVSI 749



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 47/122 (38%), Positives = 69/122 (56%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C I +  
Sbjct: 191 ISDDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCAIFSRE 250

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + + +LI    D  + W+E+ LLV  Y  Y+  M ++  I+  
Sbjct: 251 MLHLTWWPLFRDVSFYILDLIMLIVFFLDNTILWWESILLVLGYISYVSFMKFNSQIEQA 310

Query: 121 AK 122
            K
Sbjct: 311 VK 312



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 20/62 (32%), Positives = 29/62 (46%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           + +I + L I D V G TF+AAG S PE  +S+I                   F+IL  +
Sbjct: 182 LEVITNKLQISDDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVI 241

Query: 366 GL 367
           G+
Sbjct: 242 GM 243


>UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone
           sodium-calcium potassium exchanger; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           cone sodium-calcium potassium exchanger -
           Strongylocentrotus purpuratus
          Length = 651

 Score =  119 bits (286), Expect = 2e-25
 Identities = 72/224 (32%), Positives = 109/224 (48%), Gaps = 11/224 (4%)

Query: 216 EIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDC 275
           ++ SPE    QP   D  +VE+  + S   WP  K    ++T I+  P+  V  FT+PD 
Sbjct: 428 DVESPEST-EQPDMAD-MEVEEPLDIS---WP--KGWRKQVTYILLAPLVYVLYFTLPDV 480

Query: 276 EKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAV 335
            +   + W+ +TFI CI WI   SY++ WM   +GDT+ I + VMG+T LAAGTS+P+ +
Sbjct: 481 RRVESRKWYSVTFIGCIFWIAGFSYLMVWMAKEVGDTIGIEERVMGLTILAAGTSIPDLI 540

Query: 336 SSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYS 395
           +SVIVA++               FDI + L LPW+    L         V ++S GL  S
Sbjct: 541 TSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWI----LWSISQNGASVSVDSKGLFCS 596

Query: 396 AIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
                            NK+++   +G      Y  FL ++ L+
Sbjct: 597 IFLLFGMLILVVILIAVNKWRMTKIMGGCMFLFYLAFLAISLLL 640



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 24/48 (50%), Positives = 30/48 (62%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 48
           +++DV            PELF ++IG F    D+GVGTIVGSAVFNIL
Sbjct: 157 LSDDVAGATFMAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFNIL 204



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 16/34 (47%), Positives = 23/34 (67%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
           +++I D L + D V G TF+AAG S PE  +S+I
Sbjct: 148 LSVITDKLDLSDDVAGATFMAAGGSAPELFTSLI 181


>UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein ncx-5 - Caenorhabditis elegans
          Length = 591

 Score =  118 bits (284), Expect = 3e-25
 Identities = 88/331 (26%), Positives = 143/331 (43%), Gaps = 27/331 (8%)

Query: 134 DNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQ-DAK-------EKILE 185
           D ++   + +    + S  I  +   + +  Q+   I   P    DAK       + ++ 
Sbjct: 252 DEDDTSSSSSSSSSERSNKIKPVSNGVPEIRQNGRTIMVKPANDPDAKFNNQNSIKTVIT 311

Query: 186 SVDVSDK----VSASEEGKDKNVNIDMDSKPNE--------MEIASPEENLYQPTAEDNT 233
            +D  D     ++ +  GK KN N      P E        +E+A    N   P A DN 
Sbjct: 312 PIDFGDDHTIVINNNNNGKRKNGNNGTYLTPVEAINPSNGHLELAQTNGNPVPPIALDNL 371

Query: 234 DVEDGS-ENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMC 291
            +   + E  L   WP       K+  +   PI     +T+PD  KP  + +F +TFI  
Sbjct: 372 SIASSTAEKPLDLSWPEANH--KKLIYLFLAPITFPLAYTLPDVRKPSLRKFFAITFIGA 429

Query: 292 IVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXX 351
           I+WI + SY++ W    IG+T  IP  +MG+T LAAGTS+P+ ++SVIVA++        
Sbjct: 430 ILWIAAYSYLMVWWANTIGETFGIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVS 489

Query: 352 XXXXXXTFDILLCLGLPWLIKASL--TPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXX 409
                  FD+ + L +PWLI  ++    +EP    + + S GL  S              
Sbjct: 490 SSIGSNLFDVCVGLPIPWLIHFAIGVFKSEPTQN-ISVTSNGLVCSLGLLFAMLIVLLTC 548

Query: 410 FWFNKFKLDAAVGRACLAMYAMFLILATLIE 440
              +++K+D   G   +  Y  F +L  L+E
Sbjct: 549 VAISRWKMDKFFGLLMIFSYCGFCMLCILLE 579



 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 42/114 (36%), Positives = 66/114 (57%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PE F ++ G F+ + ++GVGTIVGSA FNIL V A C + +  
Sbjct: 69  ISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFSRQ 128

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 114
           V+ L WWPL RD   Y +++ +L+    DE ++W EA ++ S+Y  Y   M ++
Sbjct: 129 VLHLTWWPLFRDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAYGFFMKFN 182



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 20/60 (33%), Positives = 28/60 (46%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           +++I + L I D V G TF+AAG S PE  +S+                   TF+IL  L
Sbjct: 60  LSVITEVLAISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVL 119


>UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 643

 Score =  118 bits (284), Expect = 3e-25
 Identities = 71/251 (28%), Positives = 124/251 (49%), Gaps = 18/251 (7%)

Query: 191 DKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNK 250
           +K  A+EE   K+      S+ +++E+    +   +   E++    D S      WP  +
Sbjct: 408 EKCRANEESMSKH------SRESKVELCGVSDETEEELLEEDEQPIDLS------WP--E 453

Query: 251 SCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIG 310
           S   ++  ++  P+  +  +T+ D  +P  ++ +P+TF+M I WI   SY + W  T +G
Sbjct: 454 SGRDRVFYVIKAPLMFLMYYTMVDVRRPERRHLYPITFLMSIFWIAFFSYFMVWWATEVG 513

Query: 311 DTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWL 370
            T  IP  VMG+TFLAAGTSVP+ ++SV+VA++               FDI + L LPWL
Sbjct: 514 YTFDIPTEVMGLTFLAAGTSVPDLITSVLVARKGFGDMAVSSSIGSNLFDITVGLPLPWL 573

Query: 371 IKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYA 430
             +++         V ++S G+ YS I               +++++  ++G      Y 
Sbjct: 574 CYSAVNLG----LAVNVSSRGILYSVIMLFCMLIAVVVSIAASRWRMSKSLGACMFVFYI 629

Query: 431 MFLILATLIEL 441
           +FL+LA L+ L
Sbjct: 630 IFLVLAVLLAL 640



 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 47/125 (37%), Positives = 71/125 (56%), Gaps = 2/125 (1%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFIT-EGDIGVGTIVGSAVFNILAVAACCGIGAG 59
           +  DV            PELF + IGTFI  + ++G+GTIVGSAVFN+L V   C + + 
Sbjct: 143 LKEDVAGATFMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGMCAMFSK 202

Query: 60  MVVPLDWWPLTRDCLAYGITVSILIC-IIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 118
            V+ L WWPL RDC+ Y + + ILI   +  + + W+E+ +L+  Y  Y+  M Y+  ++
Sbjct: 203 GVLELTWWPLFRDCIFYSLALIILIIFFLSGDVIVWWESLVLLLCYFAYVIFMKYNHNVE 262

Query: 119 NFAKG 123
              KG
Sbjct: 263 RRIKG 267


>UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2); n=34;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 2
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) - Homo
           sapiens (Human)
          Length = 661

 Score =  118 bits (284), Expect = 3e-25
 Identities = 65/222 (29%), Positives = 112/222 (50%), Gaps = 7/222 (3%)

Query: 229 AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTF 288
           AE  T  E+  +     WPS      ++T ++ +PI      T+PD  KP  + +FP+TF
Sbjct: 446 AEAQTADEEEDQPLSLAWPSETR--KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITF 503

Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
              I WI   SY++ W    +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++     
Sbjct: 504 FGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDM 563

Query: 349 XXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXX 408
                     FDI + L LPWL+   +   +P    V ++S GL  + +           
Sbjct: 564 AVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP----VAVSSNGLFCAIVLLFIMLLFVIL 619

Query: 409 XFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
                K++++  +G     +Y +FL+++ L+E  +   PV++
Sbjct: 620 SIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI 661



 Score =  101 bits (242), Expect = 4e-20
 Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 7/136 (5%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PELF ++IG FI   ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + + +LI    D  + W+E+ LL++ Y  Y+  M ++  ++  
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287

Query: 121 AKGSWKWVSNMFKDNE 136
                KWV  M   N+
Sbjct: 288 -----KWVKQMINRNK 298



 Score = 38.7 bits (86), Expect = 0.32
 Identities = 21/62 (33%), Positives = 30/62 (48%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           +T+I + L I D V G TF+AAG S PE  +S+I                   F+IL  +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220

Query: 366 GL 367
           G+
Sbjct: 221 GM 222


>UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to
           Sodium/potassium/calcium exchanger
           (Na(+)/K(+)/Ca(2+)-exchange protein); n=2;
           Endopterygota|Rep: PREDICTED: similar to
           Sodium/potassium/calcium exchanger
           (Na(+)/K(+)/Ca(2+)-exchange protein) - Apis mellifera
          Length = 658

 Score =  117 bits (281), Expect = 7e-25
 Identities = 64/195 (32%), Positives = 101/195 (51%), Gaps = 7/195 (3%)

Query: 246 WPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWM 305
           WPS  S   ++T I+  PI      T+PD   PR K +F +TFI  I WI + SY++ W 
Sbjct: 463 WPS--SARKRLTYILVAPILFPLWLTLPDTRTPRGKKFFAVTFIGSIFWIAAYSYLMVWW 520

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
             + GDT+ IP  VMG+TFLAAGTS+P+ ++SVIVA++               FD+ + L
Sbjct: 521 ANVAGDTVRIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGL 580

Query: 366 GLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRAC 425
            +PWL+   L    P    V++NS+G+  S                  K++++  +G   
Sbjct: 581 PVPWLL-YGLIYGRP----VEVNSVGMVCSIAILFCMLLFVILSIACFKWRMNKGLGFTM 635

Query: 426 LAMYAMFLILATLIE 440
             +Y +F+ ++ + E
Sbjct: 636 FLLYFVFVAVSLMFE 650



 Score =  116 bits (279), Expect = 1e-24
 Identities = 50/122 (40%), Positives = 70/122 (57%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           + +DV            PELF ++IG F++  D+G+GTIVGSAVFNIL V   C I +  
Sbjct: 162 IADDVAGATFMAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAIFSRT 221

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V+ L WWPL RDC  Y  ++  LI    D Y+ WYEA +L   Y  Y+  M +++P++  
Sbjct: 222 VLSLTWWPLFRDCTFYSASLLTLIYFFRDNYIHWYEALVLFGFYLAYVSFMKWNQPMEKL 281

Query: 121 AK 122
            K
Sbjct: 282 VK 283



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 20/62 (32%), Positives = 29/62 (46%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           + +I + L I D V G TF+AAG S PE  +S+I                   F+IL  +
Sbjct: 153 LDVIIEKLEIADDVAGATFMAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVI 212

Query: 366 GL 367
           G+
Sbjct: 213 GM 214


>UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3;
            Euteleostomi|Rep: Retinal rod Na/Ca+K exchanger -
            Tursiops truncatus (Atlantic bottle-nosed dolphin)
          Length = 1014

 Score =  116 bits (279), Expect = 1e-24
 Identities = 72/264 (27%), Positives = 126/264 (47%), Gaps = 8/264 (3%)

Query: 188  DVSDKVSASEEGKDKNVNIDM-DSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKW 246
            D  D     E+G D     D  +S+  E E    EE   Q   E+  + E+  E    +W
Sbjct: 757  DNQDDAKEDEKGIDGEEEGDGGESEDEEEEEEEGEEEEEQEEEEEEQEEEEEEEPLSLEW 816

Query: 247  PSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMI 306
            P  +   A    ++  PI      T+PD  +   + +F +TF+  I+WI   SY++ W  
Sbjct: 817  PETRQKQAIYLFLL--PIVFPLWLTVPDVRRLEARKFFVITFLGSIMWIAMFSYLMVWWA 874

Query: 307  TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
              +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++               FDI + L 
Sbjct: 875  HQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLP 934

Query: 367  LPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACL 426
            LPW++ + +   +P    V ++S GL  + +                K++++  +G    
Sbjct: 935  LPWMLFSFINGLQP----VPVSSNGLFCAIVLLFLMLLFVISSIALCKWRMNKILGFTMF 990

Query: 427  AMYAMFLILATLIELNVF-FPVNV 449
             +Y +FLI++ ++E  +   PV+V
Sbjct: 991  LLYFVFLIISVMLEDRIISCPVSV 1014



 Score =  101 bits (241), Expect = 5e-20
 Identities = 45/122 (36%), Positives = 71/122 (58%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 486 ISEDVAGATFMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCALFSRE 545

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + + +LI    D  + W+E+ LL+  Y +Y+  M ++K ++ +
Sbjct: 546 ILNLTWWPLFRDITFYILDLMMLILFFLDSLIVWWESLLLLLAYALYVFTMKWNKQLELW 605

Query: 121 AK 122
            K
Sbjct: 606 VK 607



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           F + ++   + I    Y V   + +I D L I + V G TF+AAG S PE  +S+I    
Sbjct: 456 FGMLYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGIFI 514

Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
                          F+IL  +G
Sbjct: 515 SHSNVGIGTIVGSAVFNILFVIG 537


>UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3;
            Euteleostomi|Rep: Isoform 4 of Q9QZM6 - Rattus norvegicus
            (Rat)
          Length = 1153

 Score =  115 bits (276), Expect = 3e-24
 Identities = 72/290 (24%), Positives = 141/290 (48%), Gaps = 9/290 (3%)

Query: 162  QRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPE 221
            ++ +H G  +T     + K+   E+   ++    + +G +K  +    S   + E    E
Sbjct: 871  EKDEHEGQSETQADDTEVKDGEGEAEANAEDQCETAQG-EKGADGGGGSDGGDSEEEEDE 929

Query: 222  ENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRF 280
            E+  +   E+  + E+ SE  L  +WP ++   A    ++  PI      TIPD  +   
Sbjct: 930  EDEEEEEEEEEEEEEEESEEPLSLEWPESRQKQAIYLFLL--PIVFPLWLTIPDVRRQEA 987

Query: 281  KNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIV 340
            + +F +TF+  I+WI   SY++ W    +G+T+ I + +MG+T LAAGTS+P+ ++SVIV
Sbjct: 988  RKFFVITFLGSIIWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIV 1047

Query: 341  AKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXX 400
            A++               FDI + L +PWL+ + +   +P    + ++S GL  + +   
Sbjct: 1048 ARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINALQP----IPVSSNGLFCAIVLLF 1103

Query: 401  XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
                         K++++  +G     +Y +FL+++ ++E  +   PV+V
Sbjct: 1104 LMLLFVIFSIASCKWRMNKILGFTMFLLYFVFLVISVMLEDRIISCPVSV 1153



 Score =  105 bits (252), Expect = 2e-21
 Identities = 47/122 (38%), Positives = 72/122 (59%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 457 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSRE 516

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + +S+LI    D  + W+E+ LL+  Y +Y+  M ++K I+ +
Sbjct: 517 ILNLTWWPLFRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERW 576

Query: 121 AK 122
            K
Sbjct: 577 VK 578



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           F +T++   + I    Y V   + +I D L I + V G TF+AAG S PE  +S+I    
Sbjct: 427 FGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 485

Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
                          F+IL  +G
Sbjct: 486 SHSNVGIGTIVGSAVFNILFVIG 508


>UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus
            norvegicus|Rep: Isoform 3 of Q9QZM6 - Rattus norvegicus
            (Rat)
          Length = 1086

 Score =  115 bits (276), Expect = 3e-24
 Identities = 72/290 (24%), Positives = 141/290 (48%), Gaps = 9/290 (3%)

Query: 162  QRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPE 221
            ++ +H G  +T     + K+   E+   ++    + +G +K  +    S   + E    E
Sbjct: 804  EKDEHEGQSETQADDTEVKDGEGEAEANAEDQCETAQG-EKGADGGGGSDGGDSEEEEDE 862

Query: 222  ENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRF 280
            E+  +   E+  + E+ SE  L  +WP ++   A    ++  PI      TIPD  +   
Sbjct: 863  EDEEEEEEEEEEEEEEESEEPLSLEWPESRQKQAIYLFLL--PIVFPLWLTIPDVRRQEA 920

Query: 281  KNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIV 340
            + +F +TF+  I+WI   SY++ W    +G+T+ I + +MG+T LAAGTS+P+ ++SVIV
Sbjct: 921  RKFFVITFLGSIIWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIV 980

Query: 341  AKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXX 400
            A++               FDI + L +PWL+ + +   +P    + ++S GL  + +   
Sbjct: 981  ARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINALQP----IPVSSNGLFCAIVLLF 1036

Query: 401  XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
                         K++++  +G     +Y +FL+++ ++E  +   PV+V
Sbjct: 1037 LMLLFVIFSIASCKWRMNKILGFTMFLLYFVFLVISVMLEDRIISCPVSV 1086



 Score =  105 bits (252), Expect = 2e-21
 Identities = 47/122 (38%), Positives = 72/122 (59%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 457 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSRE 516

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + +S+LI    D  + W+E+ LL+  Y +Y+  M ++K I+ +
Sbjct: 517 ILNLTWWPLFRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERW 576

Query: 121 AK 122
            K
Sbjct: 577 VK 578



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           F +T++   + I    Y V   + +I D L I + V G TF+AAG S PE  +S+I    
Sbjct: 427 FGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 485

Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
                          F+IL  +G
Sbjct: 486 SHSNVGIGTIVGSAVFNILFVIG 508


>UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1
            (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=13;
            Fungi/Metazoa group|Rep: Sodium/potassium/calcium
            exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) -
            Rattus norvegicus (Rat)
          Length = 1181

 Score =  115 bits (276), Expect = 3e-24
 Identities = 72/290 (24%), Positives = 141/290 (48%), Gaps = 9/290 (3%)

Query: 162  QRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPE 221
            ++ +H G  +T     + K+   E+   ++    + +G +K  +    S   + E    E
Sbjct: 899  EKDEHEGQSETQADDTEVKDGEGEAEANAEDQCETAQG-EKGADGGGGSDGGDSEEEEDE 957

Query: 222  ENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRF 280
            E+  +   E+  + E+ SE  L  +WP ++   A    ++  PI      TIPD  +   
Sbjct: 958  EDEEEEEEEEEEEEEEESEEPLSLEWPESRQKQAIYLFLL--PIVFPLWLTIPDVRRQEA 1015

Query: 281  KNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIV 340
            + +F +TF+  I+WI   SY++ W    +G+T+ I + +MG+T LAAGTS+P+ ++SVIV
Sbjct: 1016 RKFFVITFLGSIIWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIV 1075

Query: 341  AKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXX 400
            A++               FDI + L +PWL+ + +   +P    + ++S GL  + +   
Sbjct: 1076 ARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINALQP----IPVSSNGLFCAIVLLF 1131

Query: 401  XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
                         K++++  +G     +Y +FL+++ ++E  +   PV+V
Sbjct: 1132 LMLLFVIFSIASCKWRMNKILGFTMFLLYFVFLVISVMLEDRIISCPVSV 1181



 Score =  108 bits (259), Expect = 3e-22
 Identities = 65/226 (28%), Positives = 116/226 (51%), Gaps = 5/226 (2%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 457 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSRE 516

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + +S+LI    D  + W+E+ LL+  Y +Y+  M ++K I+ +
Sbjct: 517 ILNLTWWPLFRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERW 576

Query: 121 AKG--SWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVP-IEQRHQHNGNIKTSPLRQ 177
            K   S + V+ +    +  + ++   +        K+ +P +  R   + ++  S +R 
Sbjct: 577 VKEQLSRRPVAKVMALGDLSKPSDGAIEENEQQDNKKLKLPSVLTRGSSSASLHNSIIRS 636

Query: 178 DAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKP-NEMEIASPEE 222
                +L S+D   +   S++ K +++N +    P  + E +S EE
Sbjct: 637 TIYHLMLHSLDPLGEARPSKD-KQESLNQEARVLPQTKAESSSDEE 681



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           F +T++   + I    Y V   + +I D L I + V G TF+AAG S PE  +S+I    
Sbjct: 427 FGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 485

Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
                          F+IL  +G
Sbjct: 486 SHSNVGIGTIVGSAVFNILFVIG 508


>UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1
            (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=12;
            Euarchontoglires|Rep: Sodium/potassium/calcium exchanger
            1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Homo sapiens
            (Human)
          Length = 1099

 Score =  114 bits (275), Expect = 4e-24
 Identities = 74/291 (25%), Positives = 136/291 (46%), Gaps = 11/291 (3%)

Query: 164  HQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEE---GKDKNVNIDMDSKPNEMEIASP 220
            H  +G +K +    +++E   E+   +       E   G D   + + + +  E E    
Sbjct: 815  HAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE 874

Query: 221  EENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPR 279
            EE   +   E+  + E G+E  L   WP  +   A    ++  PI      T+PD  +  
Sbjct: 875  EEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLL--PIVFPLWLTVPDVRRQE 932

Query: 280  FKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
             + +F  TF+  I+WI   SY++ W    +G+T+ I + +MG+T LAAGTS+P+ ++SVI
Sbjct: 933  SRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVI 992

Query: 340  VAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXX 399
            VA++               FDI + L +PWL+ + +   +P    V ++S GL  + +  
Sbjct: 993  VARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQP----VPVSSNGLFCAIVLL 1048

Query: 400  XXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
                          K++++  +G     +Y +FLI++ ++E  +   PV+V
Sbjct: 1049 FLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1099



 Score =  109 bits (263), Expect = 1e-22
 Identities = 66/226 (29%), Positives = 115/226 (50%), Gaps = 5/226 (2%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSRE 549

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RD   Y + + +LI    D  + W+E+ LL+  Y  Y+  M ++K I+ +
Sbjct: 550 ILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVW 609

Query: 121 AKG--SWKWVSNM--FKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
            K   S + V+ +   +D  +  D     D       LK+   +  R   + ++  S +R
Sbjct: 610 VKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLP-SLLTRGSSSTSLHNSTIR 668

Query: 177 QDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEE 222
               + +L S+D   +V  ++E +++++N    ++P     + PEE
Sbjct: 669 STIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEE 714



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           F + ++   + I    Y V   + +I D L I + V G TF+AAG S PE  +S+I    
Sbjct: 460 FGMMYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518

Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
                          F+IL  +G
Sbjct: 519 SHSNVGIGTIVGSAVFNILFVIG 541


>UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchanger
           2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2)
           (Retinal cone Na-Ca+K exchanger) (Solute carrier family
           24 member 2).; n=1; Takifugu rubripes|Rep:
           Sodium/potassium/calcium exchanger 2 precursor
           (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone
           Na-Ca+K exchanger) (Solute carrier family 24 member 2).
           - Takifugu rubripes
          Length = 449

 Score =  109 bits (262), Expect = 2e-22
 Identities = 65/228 (28%), Positives = 110/228 (48%), Gaps = 8/228 (3%)

Query: 223 NLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKN 282
           NL  P   +  + ++    SL  WP   +   +IT +V  PI      T+PD  +   + 
Sbjct: 229 NLKVPQILEEEEEDEDQPLSL-AWPD--TLRKQITYLVILPIVFPLWLTLPDVRRESSER 285

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           +FP+TFI  I WI   SY++ W    +G+T  + + +MG+T LAAGTS+P+ ++SVIVA+
Sbjct: 286 FFPITFIGSISWIAFFSYLMVWWAHQVGETFWVTEEIMGLTILAAGTSIPDLITSVIVAR 345

Query: 343 QXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXX 402
           +               FDI + L  PWL+   +   +P    V ++S GL  + +     
Sbjct: 346 KGLGDMAVSSSVGSNIFDITVGLPFPWLLFNIINDFQP----VGVSSNGLFCAIVLLFLM 401

Query: 403 XXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
                      K+K+   +G     +Y +FL+++ ++E  +   PV V
Sbjct: 402 LLFVIMSIAACKWKMSKILGSTMFLLYFVFLVVSVMLEDKIISCPVTV 449



 Score = 99.1 bits (236), Expect = 2e-19
 Identities = 46/125 (36%), Positives = 70/125 (56%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PELF +VIG F++  ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 53  ISDDVAGATFMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVIGMCALFSKE 112

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V+ L WWPL RD   Y + + +LI    D  +   E+  L+S YG Y+  M ++   + F
Sbjct: 113 VLHLTWWPLFRDVSFYIVGLLMLIYFFLDNQITVLESVSLLSFYGCYVTFMKFNSKFERF 172

Query: 121 AKGSW 125
            K ++
Sbjct: 173 IKSAF 177



 Score = 40.7 bits (91), Expect = 0.079
 Identities = 22/62 (35%), Positives = 30/62 (48%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           +T+I + L I D V G TF+AAG S PE  +SVI                   F+IL  +
Sbjct: 44  LTVITEKLEISDDVAGATFMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVI 103

Query: 366 GL 367
           G+
Sbjct: 104 GM 105


>UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium
           exchanger; n=5; Coelomata|Rep: Potassium-dependent
           sodium-calcium exchanger - Aedes aegypti (Yellowfever
           mosquito)
          Length = 207

 Score =  108 bits (260), Expect = 3e-22
 Identities = 47/123 (38%), Positives = 71/123 (57%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +T+DV            PELF +VIG F++  D+G+GTIVGSAVFNIL V   C + +  
Sbjct: 51  ITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKT 110

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           ++ L WWPL RDC  Y +++  LI    D  ++W+EA +L  +Y  Y   M +++ ++  
Sbjct: 111 LLTLTWWPLFRDCTFYSVSLLTLIYFFRDNSIEWWEALVLFIIYIAYAVFMKFNQTVERC 170

Query: 121 AKG 123
             G
Sbjct: 171 CGG 173



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 23/70 (32%), Positives = 32/70 (45%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           + +I + L I D V G TF+AAG S PE  +SVI                   F+IL  +
Sbjct: 42  LDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVI 101

Query: 366 GLPWLIKASL 375
           G+  L   +L
Sbjct: 102 GMCALFSKTL 111


>UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n=2;
           Ostreococcus|Rep: K-independent Na+/Ca2+ exchanger JSX -
           Ostreococcus tauri
          Length = 443

 Score =  107 bits (256), Expect = 8e-22
 Identities = 64/198 (32%), Positives = 97/198 (48%), Gaps = 8/198 (4%)

Query: 235 VEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVW 294
           VED  E+  ++WP   S L     +++ P    F F+IP+C   + +NWF +TF+  I W
Sbjct: 237 VED--EDKSFEWPD--SSLGIPLHVISLPWRFAFHFSIPNCALKQRENWFAMTFLASISW 292

Query: 295 IGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXX 354
           I  +SY +      +G  + IP+ VMG   +AAGTS+P+A+ S+ VAK            
Sbjct: 293 ISLISYCMVSWAARVGCVIGIPEVVMGTLVVAAGTSIPDALGSIAVAKAGEGDMAVANAV 352

Query: 355 XXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNK 414
               FDI L LGLPWLI   + P +PG   + I +  L  S               +FN+
Sbjct: 353 GSNIFDIWLGLGLPWLI---ILPTKPGR-MISIQTSQLIPSMSILFGVLLLYYLMLFFNR 408

Query: 415 FKLDAAVGRACLAMYAMF 432
           ++L  + G   +  Y +F
Sbjct: 409 WQLTRSAGIVFMCTYVVF 426



 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 42/128 (32%), Positives = 66/128 (51%), Gaps = 2/128 (1%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEG--DIGVGTIVGSAVFNILAVAACCGIGA 58
           ++ DV            PELF + +     +   +IG+  IVGSAVFN+L +     + A
Sbjct: 74  LSEDVAGATFMAAGSSAPELFSSGMSLISPDATNEIGISAIVGSAVFNMLFIVGATVLCA 133

Query: 59  GMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 118
           G  + LDW P+TRDC+ Y + V  ++ I +D  + WYE  + V LY  Y+  M Y+  + 
Sbjct: 134 GCSLDLDWRPVTRDCMFYAMAVLTVLLIFYDGRITWYEGLICVLLYATYVLCMCYNDVLM 193

Query: 119 NFAKGSWK 126
            +  G+ K
Sbjct: 194 RWMGGASK 201


>UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias
           amurensis|Rep: Na+/Ca2+ exchanger - Asterias amurensis
           (Starfish)
          Length = 616

 Score =  106 bits (254), Expect = 1e-21
 Identities = 51/121 (42%), Positives = 71/121 (58%), Gaps = 1/121 (0%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF+++IG    E D+GVGTIVG+AVFNIL + A     AG 
Sbjct: 135 LSEDVAGATFMAAGSSAPELFISIIGVS-KESDVGVGTIVGTAVFNILIIIALTAALAGQ 193

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V+ LDW PL RDC++YGI++   I    D  ++ YEA +L+ LY  YI +M  +  I N 
Sbjct: 194 VLKLDWRPLVRDCISYGISIICFIIFAWDGVIEIYEAIILLGLYVAYIVLMKLNSRIMNL 253

Query: 121 A 121
           +
Sbjct: 254 S 254



 Score = 94.7 bits (225), Expect = 5e-18
 Identities = 63/207 (30%), Positives = 100/207 (48%), Gaps = 15/207 (7%)

Query: 248 SNKSCLAKITK----IVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVA 303
           S   CL  + K    IV++P    F +TIP+C  P++K  + ++F+M IVWI  LS  + 
Sbjct: 404 SRCGCLRLVLKWAMFIVSFPFMCAFTWTIPNCSNPKYKRLYLVSFLMSIVWIAGLSTAMV 463

Query: 304 WMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILL 363
            ++   G  L I    MG+ F+A GTSVP+A+SS++VA+                FDI L
Sbjct: 464 TLVERAGCILNIDHYFMGLVFVAVGTSVPDALSSILVARDGFGDMAVSNAIGSNVFDINL 523

Query: 364 CLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXX----------XXXXXXXXXFWFN 413
            LGLP+ I+  +T + P +   + + M L   A+                      F   
Sbjct: 524 GLGLPFFIRILIT-SSPINLLSETDEMMLASGALLMAPHAKFGFILLAILFFTLIVFCGV 582

Query: 414 KFKLDAAVGRACLAMYAMFLILATLIE 440
           +F+L+  VG + + +Y  F++ A L E
Sbjct: 583 RFQLNKFVGVSFVMLYVAFIVYALLQE 609


>UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome
           shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 13
           SCAF14555, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 647

 Score =  103 bits (248), Expect = 7e-21
 Identities = 61/194 (31%), Positives = 98/194 (50%), Gaps = 6/194 (3%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           +++DV            PELF ++IG FI   ++G+GTIVGSAVFNIL V   C + +  
Sbjct: 183 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 242

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V+ L WWPL RD   Y + + +LI    D  + W+E+ +LV  Y VY+  M ++  I+  
Sbjct: 243 VLHLTWWPLFRDVSFYILDLVMLIVFFLDNVIMWWESMMLVGGYTVYVIFMKFNVQIERA 302

Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKD-----LKLSTHILKIDV-PIEQRHQHNGNIKTSP 174
            K       N+ K    ++  +  KD     L L T  L + + P  QR   + ++  S 
Sbjct: 303 FKTQLYKHRNIVKIIAVEEPEKVSKDVIQVRLLLMTTPLSVQLKPSLQRGGSSASLHNST 362

Query: 175 LRQDAKEKILESVD 188
           +R    + ++ ++D
Sbjct: 363 MRNTIFQLMIHTLD 376



 Score = 97.5 bits (232), Expect = 6e-19
 Identities = 50/175 (28%), Positives = 94/175 (53%), Gaps = 5/175 (2%)

Query: 276 EKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAV 335
           +K + + +F +TF+  I+WI   SY++ W    +G+T+ I + +MG+T LAAGTS+P+ +
Sbjct: 477 DKKKSRRFFVVTFLGSILWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLI 536

Query: 336 SSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYS 395
           +SVIVA++               FDI + L +PWL+ +++    P    V ++S GL  +
Sbjct: 537 TSVIVARKGMGDMAVSSSVGSNIFDITVGLPVPWLMYSAIHGLAP----VAVSSNGLFCA 592

Query: 396 AIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFF-PVNV 449
            +                 +K++ A+G     +Y +FL+L+ ++E  +   PV++
Sbjct: 593 IVLLFIMLLFVIISIASCNWKMNKALGSTMFLLYFIFLVLSVMLEDRIIICPVSI 647



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 20/60 (33%), Positives = 27/60 (45%)

Query: 308 IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           +I   L I D V G TF+AAG S PE  +S+I                   F+IL  +G+
Sbjct: 176 VITHKLAISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 235


>UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger; n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger - Nasonia
           vitripennis
          Length = 418

 Score =  102 bits (245), Expect = 2e-20
 Identities = 52/160 (32%), Positives = 87/160 (54%), Gaps = 5/160 (3%)

Query: 281 KNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIV 340
           K +F +TFI  I+WI + SY++ W   ++GDT+ IP  VMG+TFLAAGTS+P+ ++SVIV
Sbjct: 256 KKFFAVTFIGSILWIAAYSYLMVWWANVVGDTVQIPPEVMGLTFLAAGTSIPDLITSVIV 315

Query: 341 AKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXX 400
           A++               FD+ + L +PWL+   L    P    V++NS+G+  S     
Sbjct: 316 ARKGFGDMAVSSSVGSNIFDVTVGLPVPWLL-YGLIYGTP----VEVNSVGMVCSIAILF 370

Query: 401 XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIE 440
                      F K++++  +G     +Y +F+ ++ + E
Sbjct: 371 CMLLFVILSIAFFKWRMNKGLGFTMFLLYFVFVAVSLMFE 410


>UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calcium
           exchanger; n=2; Eumetazoa|Rep: Testis potassium
           dependent sodium/calcium exchanger - Strongylocentrotus
           purpuratus (Purple sea urchin)
          Length = 652

 Score = 98.3 bits (234), Expect = 4e-19
 Identities = 57/194 (29%), Positives = 97/194 (50%), Gaps = 11/194 (5%)

Query: 259 IVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDS 318
           ++++P    F +TIP+C  PR + W+  +F++ I WI +LS+ +  ++  IG  L I D 
Sbjct: 453 VISFPFMCAFSWTIPNCSVPRLRKWYVASFLLSIFWIAALSFGMVTLVVKIGCILNISDY 512

Query: 319 VMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK------ 372
            MG+  +A GTSVP+A+SS++VA+                FDI L +GLP+LI+      
Sbjct: 513 TMGLVIVAVGTSVPDALSSILVARDGYGDMAVSNAIGSNVFDINLGIGLPYLIRIAINGG 572

Query: 373 ---ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFN--KFKLDAAVGRACLA 427
              A L PA+   +          ++              F F   +F+L+A +G +   
Sbjct: 573 TNIALLNPADQLRFDDGAFGPIPPHAKFGFILLLILLFTIFAFTAVRFRLNAVIGVSFAI 632

Query: 428 MYAMFLILATLIEL 441
           MY +F++ A + E+
Sbjct: 633 MYVLFMVYAFVQEI 646



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 50/122 (40%), Positives = 66/122 (54%), Gaps = 1/122 (0%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++ DV            PELF  VIG    E D+GVGTIVGSAVFNIL + A     AG 
Sbjct: 149 LSEDVAGATFMAAGSSAPELFTAVIGVAF-ESDVGVGTIVGSAVFNILIIIALTAALAGQ 207

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
           V+ LDW PL RD   YG+++   I    D    W+E+ +LV LY +Y+ +M  +  I + 
Sbjct: 208 VLNLDWRPLARDSFFYGLSLVCFIVFSWDTEFTWWESLILVILYVIYLILMKVNPIIMDK 267

Query: 121 AK 122
            K
Sbjct: 268 TK 269



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 15/34 (44%), Positives = 24/34 (70%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
           + +I +TL + + V G TF+AAG+S PE  ++VI
Sbjct: 140 LEVISETLSLSEDVAGATFMAAGSSAPELFTAVI 173


>UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep:
           CG12061-PB.3 - Drosophila melanogaster (Fruit fly)
          Length = 110

 Score = 97.5 bits (232), Expect = 6e-19
 Identities = 46/92 (50%), Positives = 56/92 (60%), Gaps = 1/92 (1%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           MT DV            PELFVN +GTF+T GDIG+GTIVGS+VFNIL +A  CGI    
Sbjct: 19  MTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-Q 77

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYV 92
              LDWWP+TRD   Y I ++ L  ++ D  V
Sbjct: 78  PTKLDWWPVTRDTAWYLIAIASLTYVLWDSLV 109


>UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis
           pacifica SIR-1|Rep: Ca2+/Na+ antiporter - Plesiocystis
           pacifica SIR-1
          Length = 361

 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 4/114 (3%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFI--TEGDIGVGTIVGSAVFNILAVAACCGIGA 58
           +++ V            PEL   ++  F        GVG+IVGSA+F IL V     +  
Sbjct: 38  LSSSVAGATLLAFGTSAPELSTALVALFAEGAHASTGVGSIVGSAIFQILVVVGFAAVVR 97

Query: 59  GMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
                LDW P+ RD L Y +++ +LI  +HD+ +   EA +LV  YG+Y+ +M+
Sbjct: 98  AST--LDWRPVIRDALFYALSIVLLIAFVHDDRLTLVEAAILVGSYGLYLGVMW 149



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 8/185 (4%)

Query: 254 AKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTL 313
           A++ + +TWPI  + L  +PD        W    F + +  IG   Y + +    I   L
Sbjct: 181 ARLRRALTWPIDRL-LALVPDPASQA--RWTLPVFALSLGLIGFSCYWLVFAAEAIAQAL 237

Query: 314 MIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKA 373
            +P +++ +T LA G+S+PE VSS  VA+Q               FDIL+ LGLP L+  
Sbjct: 238 AVPPAIIALTILAGGSSIPELVSSATVARQGRADMAVANAVGSNIFDILVSLGLPVLLYC 297

Query: 374 SLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFL 433
            L     G     I S     S +                +F+   A G   ++ YA ++
Sbjct: 298 LLHGDLVGLGGATITS-----SLVLLGATLAMVVGLLAAQRFRASRAFGALLISAYAAYV 352

Query: 434 ILATL 438
           + A L
Sbjct: 353 VAAYL 357


>UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+
           exchanger-like protein; n=1; Microscilla marina ATCC
           23134|Rep: Putative K+-dependent Na+/Ca+ exchanger-like
           protein - Microscilla marina ATCC 23134
          Length = 389

 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 9/182 (4%)

Query: 256 ITKIVTWPIHLVFLFTIPDCE-KPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLM 314
           + K + +P+  + +  IPD E KPR   W    F++ +V I   SY +      +   + 
Sbjct: 209 LQKTLGYPVEFL-MNLIPDPEEKPR---WTIPVFLLSLVIIAGASYFLVVAAEALAKAMD 264

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
           IP +++ +T LA G+S+PE +SS IVAKQ               FDIL+ LGLP LI   
Sbjct: 265 IPPAIIALTILAGGSSIPEMISSAIVAKQGRGDMAIANAIGSNIFDILMSLGLPVLIYIL 324

Query: 375 LTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLI 434
           +     G     +    +  S I             +  KFK     G   + +Y ++++
Sbjct: 325 I----KGQPLTDLGGANITSSIILLFTTLIVVVLLLFVQKFKATRPFGLFLIFLYLIYVV 380

Query: 435 LA 436
            A
Sbjct: 381 AA 382



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 18  PELFVNVIGTFITEGD--IGVGTIVGSAVFNILAVAACCGIGAGMVVP---LDWWPLTRD 72
           PE+   +   F+   +   GVGTIVGSA+F IL V     IG   VV    L+W P+ RD
Sbjct: 55  PEISTALFALFLEGANPATGVGTIVGSAIFQILVV-----IGFAAVVKTSYLNWRPVMRD 109

Query: 73  CLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
            + Y  +V +LI  + D      E    V  Y +Y+ +++
Sbjct: 110 SIFYAFSVGLLILFVADNKFTLIEGIAFVCSYFLYLFVLF 149


>UniRef50_UPI000155609B Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger NCKX1; n=1;
           Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger NCKX1 -
           Ornithorhynchus anatinus
          Length = 543

 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 38/148 (25%), Positives = 74/148 (50%), Gaps = 4/148 (2%)

Query: 293 VWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXX 352
           V + + S++V      +G+T+ I + +MG++ LAAGTS+P+ ++SVIVA++         
Sbjct: 390 VQVWAFSFLVFLWAAQVGETIGISEEIMGLSILAAGTSIPDLITSVIVARKGLGDMAVSS 449

Query: 353 XXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWF 412
                 FDI + L +PW + +      P    V ++S GL  + +               
Sbjct: 450 SVGSNIFDITVGLPVPWFLYSLFNGLRP----VAVSSNGLFCAIVLLFLMLLFVITSIAS 505

Query: 413 NKFKLDAAVGRACLAMYAMFLILATLIE 440
            K+K++  +G     +Y +FL+++ ++E
Sbjct: 506 CKWKMNKLLGFTMFVLYFVFLVISVMLE 533



 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 23/70 (32%), Positives = 42/70 (60%)

Query: 54  CGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 113
           C + +  ++ L WWPL RD   Y + + +LI    D  V W+E+ LL++ Y +Y+  M +
Sbjct: 144 CALCSREILRLTWWPLFRDVSFYILDLLMLIAFFSDGTVAWWESLLLLAAYALYVFAMKW 203

Query: 114 DKPIQNFAKG 123
           ++P++ + KG
Sbjct: 204 NRPLEAWVKG 213


>UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 209

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 30/60 (50%), Positives = 37/60 (61%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           + +DV            PE F +VIG FIT+GDIG+GTIVGSAVFNIL + A C  G  +
Sbjct: 126 LKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVFNILFIVAICAGGTAL 185


>UniRef50_Q4SAM5 Cluster: Chromosome undetermined SCAF14681, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14681,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 473

 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 42/140 (30%), Positives = 66/140 (47%), Gaps = 7/140 (5%)

Query: 171 KTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAE 230
           K S L + AK+K    V+ S+K +      DKN+    +S   E+E+  P         E
Sbjct: 59  KASILHKIAKKKC--QVEDSEKANGVASRSDKNLP---NSSSVEVEVTPPMNGTAGQEGE 113

Query: 231 DNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIM 290
              + E+  +     WP  +S   ++T ++  PI L    T+PD  KP  K +FP+TF+ 
Sbjct: 114 TAEEEEEEDQPLSLSWP--ESTRKRLTYLLIVPIVLPLWLTLPDVRKPSSKKFFPITFLG 171

Query: 291 CIVWIGSLSYIVAWMITIIG 310
            I WI   SY++ W    +G
Sbjct: 172 AICWIAFFSYLMVWWAHQVG 191


>UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr7 scaffold_42, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 560

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 85/354 (24%), Positives = 148/354 (41%), Gaps = 40/354 (11%)

Query: 32  GDIGVGTIVGSAVFNILAVAACCGI--GAGMVVPLD----WW-PLTRDCLAYGITVSILI 84
           G +G GT+VGSA F++  + A C +   AG +  +     W   L     AY + + I++
Sbjct: 156 GGLGPGTLVGSAAFDLFPIHAVCVVVPKAGELKKISDVGVWLVELFWSFWAY-VWLYIIL 214

Query: 85  CIIHDEYVQWYEAFLLVSLYGVYICIMY-YDKPIQNFAKGSWKWVSNMFKDNEEKQDAEN 143
            +     +  +EA L V  +G+ +   Y  DK         W ++S      E  +D   
Sbjct: 215 EVWTPNVITIWEALLTVLQFGLLLIHAYAQDK--------QWPYLSLPLPRTERPEDWVP 266

Query: 144 GKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKN 203
            +        +  D    +  Q NGNI            +   +  S+    S E   KN
Sbjct: 267 DEAASRKQDKIAGD-ECSELFQENGNIVDIFSIHSGDGSVYHRISGSEVAEPSNEHFQKN 325

Query: 204 VNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT-KIVTW 262
           + ++ DS    +     ++ +   T E +   E    ++++ W      +A+I  +++  
Sbjct: 326 IILE-DS---HLLSLWKQQFVDAFTLESS---ESRKLDNIYLW------VARIFWQLLLL 372

Query: 263 PIHLVFLFTIPDCEKPRFKN-WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMG 321
           P   +F F  P    P   + WF   FI  +++I  ++YIV  +  +I  T  I   V+ 
Sbjct: 373 PWRFLFAFVPP----PHIAHGWF--AFICSLIFISGIAYIVTKLTDLISCTSGINSYVIA 426

Query: 322 ITFLAAGTSVPEAVSSVIVA-KQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
            T LAAGTS P+ V+S I A +Q              + +I + +G+PWLI  +
Sbjct: 427 FTALAAGTSWPDLVASKIAAERQTTADSAIANIICSNSVNIYMGIGIPWLINTT 480


>UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a;
           n=7; Caenorhabditis|Rep: Na/ca exchangers protein 2,
           isoform a - Caenorhabditis elegans
          Length = 975

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 42/153 (27%), Positives = 70/153 (45%), Gaps = 6/153 (3%)

Query: 222 ENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFK 281
           E L     +D+ D  +  E+   K P    C+  +  ++T P  L F  TIP  +   F 
Sbjct: 745 EALVVSAGDDDDDEGEDGEDGEEKEPEEPGCMDYVMHVLTVPWKLTFA-TIPPTDY--FG 801

Query: 282 NWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA 341
            W   TF++ I  IG L+ +V  + +  G  + + D+V  I+F+A GTSVP+  +S + A
Sbjct: 802 GW--ATFVVAIFMIGVLTAVVGDLASQFGCWVGLKDAVTAISFVALGTSVPDTFASKVSA 859

Query: 342 KQ-XXXXXXXXXXXXXXTFDILLCLGLPWLIKA 373
            Q                 ++ L +G+ W + A
Sbjct: 860 VQDKYADNAVGNVTGSNAVNVFLGIGIAWSMAA 892



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 22  VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
           + VI      GD+G  TIVGSA FN+  + A C
Sbjct: 135 IEVIARGFEAGDLGPNTIVGSAAFNLFMIIAIC 167


>UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus
           kandleri|Rep: Ca2+/Na+ antiporter - Methanopyrus
           kandleri
          Length = 329

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 1/111 (0%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           ++  V            PE   ++    +   ++GVGTI+GSAV+N+  +     + AG 
Sbjct: 56  LSESVAGATLAAIGTSAPEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGLAALAAGG 115

Query: 61  VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 111
           +  L+     RD L Y + + +++  + D  V   EA   V+LYG+Y+ +M
Sbjct: 116 LT-LERAVYRRDVLFYLLALVVVLVSLWDRVVLRVEALAWVALYGLYVLLM 165



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXX 349
           + +V I +LS ++        +   + +S + +   AAGTSVP+ ++SV  A++      
Sbjct: 193 VAVVGIAALSDLMVRATVDFCEGFGLSESRVSLLLNAAGTSVPDTLASVHAARRGFGSLA 252

Query: 350 XXXXXXXXTFDILLCLGLPWLIKASLTP 377
                   TFD+L+CLG+P L   S TP
Sbjct: 253 VSNAVGSNTFDLLVCLGVP-LSLVSRTP 279


>UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative,
           expressed; n=6; Magnoliophyta|Rep: Magnesium/proton
           exchanger, putative, expressed - Oryza sativa subsp.
           japonica (Rice)
          Length = 523

 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 85/355 (23%), Positives = 143/355 (40%), Gaps = 43/355 (12%)

Query: 29  ITEGDIGVGTIVGSAVFNILAVAACCGI--GAGM---VVPLDWW--PLTRDCLAYGITVS 81
           +T G +G GT+VGSA F++  + A C +   AG    +  L  W   L     AY I + 
Sbjct: 117 LTAGGLGPGTLVGSAAFDLFPIHAVCVVMPRAGSKKKISDLGVWLVELFWSFWAY-IWLY 175

Query: 82  ILICIIHDEYVQWYEAFLLVSLYGVYICIMY-YDKPIQNFAKGSWKWVSNMFKDNEEKQD 140
           I++ +     +  +EA L V  YG+ +   Y  DK         W +VS      E  +D
Sbjct: 176 IILEVWTPRVITLWEALLTVLQYGLLLLHAYAQDK--------RWPYVSIPLARGERPED 227

Query: 141 AENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGK 200
               +D           V  +  +   G+I          E I   VD+    S S EG 
Sbjct: 228 WVPAEDAS---------VDYDDNYDGIGDILPGQ-----NEDI---VDIFSAHSYSNEGY 270

Query: 201 DKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT--- 257
                 D++     + + +  E+ +  +      V+  +  S      + +CL  I    
Sbjct: 271 HHVSEEDVEESSTGLTLKNKWEDTHWFSIWWQQFVDAATLESSVSRKMDSTCLRVIGISW 330

Query: 258 KIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPD 317
            ++  P  ++F F +P  E      W  + FI  +++I  ++Y V  +   I     +  
Sbjct: 331 NLIIAPWKMLFAF-VPPYEIAH--GW--IAFICSLIFISGIAYGVTKITDQISCVTGVSP 385

Query: 318 SVMGITFLAAGTSVPEAVSSVIVA-KQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
            V+  T LAAGTS P+ V+S I A +Q              + +I + +G+PWL+
Sbjct: 386 YVIAFTALAAGTSWPDLVASKIAAERQITADSAITNITCSNSVNIYVGIGVPWLV 440


>UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6
           precursor (Na(+)/Ca(2+)-exchange protein 6); n=2;
           Caenorhabditis|Rep: Putative sodium/calcium exchanger 6
           precursor (Na(+)/Ca(2+)-exchange protein 6) -
           Caenorhabditis elegans
          Length = 590

 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 1/106 (0%)

Query: 267 VFLFTIPDCEKPRFKNWFPLT-FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFL 325
           V  FT    E P +K+      F+M I WI  +S  V  ++T++G    +   V+G+T L
Sbjct: 414 VLFFTELHKEPPFYKSLISYAGFLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTIL 473

Query: 326 AAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
           A   S+ + ++ V VAKQ               F++L+  GLP+ I
Sbjct: 474 AWSNSIGDLIADVSVAKQGYPRMAMAAAIGGQLFNLLIGFGLPFTI 519


>UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to
           sodium-calcium exchanger; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to sodium-calcium
           exchanger - Strongylocentrotus purpuratus
          Length = 766

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 9/127 (7%)

Query: 247 PSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMI 306
           PS   C   I   +T+   ++F    P   K  F  W P  F+  +++I +L+ +V  + 
Sbjct: 567 PSKMDC---IMHFITFFWKVIFAMVPP---KNYFGGW-P-AFLGSLLFIFALTAVVEQIA 618

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXXXXXXXXXXXTFDILLCL 365
           T++    +I  SV GIT +A GTSVP+  +S   A Q               + ++ L L
Sbjct: 619 TLLSCVALIEPSVAGITIIALGTSVPDTFASRTAAIQDQHADAAIGNITGSNSVNVFLGL 678

Query: 366 GLPWLIK 372
           GLPW+IK
Sbjct: 679 GLPWIIK 685


>UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeba
           histolytica HM-1:IMSS|Rep: Na/Ca,K-exchanger - Entamoeba
           histolytica HM-1:IMSS
          Length = 575

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 23/117 (19%), Positives = 53/117 (45%)

Query: 255 KITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLM 314
           +I  +  WP+ ++  +TIPD +        P+T ++ +++IG  +++  +    + + + 
Sbjct: 379 RIVYVFNWPLLVILAYTIPDVKIKTCARMTPVTILISLLYIGVFAFVGVFCGYRLSEVIT 438

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
            P  V+G TF+A   S+   +S  +  +                F   + + +PW+I
Sbjct: 439 CPPDVLGFTFVALFLSIRHIISGWVSGRMMCANLAILNSYSMSLFFTNVAIVIPWMI 495


>UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6); n=30;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 6
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) - Homo
           sapiens (Human)
          Length = 584

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 8/180 (4%)

Query: 267 VFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFL 325
           V  F   D + PR    F  L F+   +WI + +  V  ++  +G    + ++V+G+T L
Sbjct: 404 VTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLL 463

Query: 326 AAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWV 385
           A G S+ +A S   +A+Q               F+IL+ +GL  L++ S +     H  V
Sbjct: 464 AWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRS-----HTEV 518

Query: 386 KINSMGLEYSAIXXX--XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNV 443
           K+   GL    +                   F+L    G   L  Y  FL++A L E  V
Sbjct: 519 KLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGV 578


>UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7
           precursor (Na(+)/Ca(2+)-exchange protein 7); n=2;
           Caenorhabditis|Rep: Putative sodium/calcium exchanger 7
           precursor (Na(+)/Ca(2+)-exchange protein 7) -
           Caenorhabditis elegans
          Length = 672

 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 42/179 (23%), Positives = 72/179 (40%), Gaps = 6/179 (3%)

Query: 266 LVFLFTIPDCEKPRFKNWFPLT-FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITF 324
           L+ +FT    +   +K  +  + FIM I WI  +S  V  ++T++G    +   V+G+T 
Sbjct: 495 LIMVFTELSVQPKYYKEIYSYSGFIMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTI 554

Query: 325 LAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYW 384
           LA   S+ + ++ V V KQ               F++L+  GLP+ I A L     G Y 
Sbjct: 555 LAWSNSIGDLIADVSVVKQGYPRMAMAAAIGGPLFNLLMGFGLPFTI-AKL----QGKYI 609

Query: 385 VKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNV 443
               +       +                KF+L        +++Y  F++   L E  V
Sbjct: 610 SMTINPTYRLLILFLAISLLATLIGIPVQKFRLQRPHAAVLISIYIAFIVFVILSETGV 668


>UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 441

 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA-KQX 344
           +TF++ + +I  L+ I+  + TI G  + +   V  ITF+A GTS+P+  +S   A  + 
Sbjct: 269 ITFVVALCFIAVLTAIIGDLATIFGCLIGLLAPVTAITFVALGTSLPDTFASKTAAVNEA 328

Query: 345 XXXXXXXXXXXXXTFDILLCLGLPWLIKA 373
                        + ++ L LGLPWLI A
Sbjct: 329 TADNSIGNVTGSNSVNVFLGLGLPWLIAA 357


>UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 837

 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 37/143 (25%), Positives = 71/143 (49%), Gaps = 8/143 (5%)

Query: 256 ITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMI 315
           I   +T+   ++F F  P   +P    W P  F++ +++I +L+ ++  +  ++G  + +
Sbjct: 641 IMHFLTFFWKVLFAFIPP---RPLLGGW-P-AFVVSLLFIAALTAVIEQLGKLLGCVVDL 695

Query: 316 PDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
            +SV GIT +A GTS+P+ ++S   A Q               + ++ L LGLPW++   
Sbjct: 696 RNSVTGITIIAIGTSLPDTMASRSAALQDTGADAAIGNITGYNSVNVFLGLGLPWVMSTC 755

Query: 375 LTPAEPGHYWVKINSMGLEYSAI 397
              A    Y  K++S  L +S +
Sbjct: 756 YHAARGTVY--KVSSGNLAFSVL 776


>UniRef50_A0CH97 Cluster: Chromosome undetermined scaffold_18, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_18,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 543

 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 54/258 (20%), Positives = 97/258 (37%), Gaps = 7/258 (2%)

Query: 191 DKVSASEEGKDKNVNID---MDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWP 247
           +  S+  +   +N+N D   M++    +E    +E + +   E     +   E    K  
Sbjct: 286 EPASSVPDSHHQNINEDIPLMENNDIPIEHQKDQEGVQENDQEQEQQQQQEQEGGKQKLT 345

Query: 248 SNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMIT 307
             K  L K   I+ +P HL+  F     +   + N   L  ++ +  +  L +++ W I 
Sbjct: 346 LPKGGLDKFLFILFFPAHLICHFIPTPKDDADYVNII-LDLLISLAIVTGLYFLIDWWIF 404

Query: 308 IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
            I D   IP  V+G  FL    S   A   + +AK+                   LC+G+
Sbjct: 405 EIFDGTGIPIQVLGFIFLGVLVSTQLAYHQIDIAKEELQLKFTQAFFQTAICKSSLCMGI 464

Query: 368 PWLIKASLTPAEPGHY-WVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACL 426
            W I+ SL   + G       +S       I             W  +F L  +  +  +
Sbjct: 465 TWGIQ-SLINIDTGLVRRSSKHSKTFAVCIIIVCGLVAFLLFQCWLKRFILAKSEAQKYM 523

Query: 427 AMYAMFL-ILATLIELNV 443
            +Y + L I+A ++ L+V
Sbjct: 524 VVYCLLLIIIAVIVPLDV 541



 Score = 34.7 bits (76), Expect = 5.2
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 4/96 (4%)

Query: 27  TFITEGDIGVGTIVGSAVFNILAVAA--CCGIGAGMVVPLDWWPLTRDCLAYGITVSIL- 83
           TF +E D+ V TI+GS  F I  V +             LD W   RD   Y +++ +L 
Sbjct: 79  TFSSESDLAVSTIIGSDAFMIFFVFSYILYKYPTHSHGVLDTWITIRDAFFYILSLFVLF 138

Query: 84  ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQN 119
           ICI+ D ++    A +L+ +Y   I  ++  + +++
Sbjct: 139 ICILLD-FLNIGTAVILLVVYFANIIFIFNSENVKS 173


>UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein ncx-3 - Caenorhabditis elegans
          Length = 807

 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 2/95 (2%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXX 347
           F++ ++ IG ++ +V  + +I G  + + D+V  IT +A GTS+P+  +S I A+     
Sbjct: 637 FVVALIGIGLVTAVVGDVASIFGCMVGLKDAVTAITLVALGTSLPDTFASKIAAESDDTA 696

Query: 348 XXXXXXXXXX-TFDILLCLGLPWLIKASLTPAEPG 381
                      + ++ L LGLPW+I ASL  A  G
Sbjct: 697 DNAVGNVTGSNSVNVFLGLGLPWVI-ASLYWASKG 730



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 5/96 (5%)

Query: 22  VNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG-MVVPLDWWPLTRDCLAYG--- 77
           + ++G     GD+G GTIVGSA FN+  ++A C    G     ++ + +      +G   
Sbjct: 112 IEIVGNGFKAGDLGPGTIVGSAAFNLFCISAICVFAVGTQTKRIELYRVFVVTAFFGTFA 171

Query: 78  -ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
            I V +++ +I    V  +EA L +  + + + + Y
Sbjct: 172 YIWVFLVLIVITPNVVDVWEAILTLLFFIILVVVSY 207


>UniRef50_A0DA69 Cluster: Chromosome undetermined scaffold_43, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_43,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 198

 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 1/123 (0%)

Query: 250 KSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITII 309
           K  L K+  I+ +PIHL+ L+ +P   +        L F + +V +    Y++ W    +
Sbjct: 3   KESLDKVLFIIFFPIHLI-LYLLPSYNENVVPKKLVLCFFLNLVLLCGCYYLIDWWAFEL 61

Query: 310 GDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPW 369
                IP  ++G+ FL   T +  A  ++ VAK                  I LC GLPW
Sbjct: 62  ALATGIPLQLIGMIFLGFFTQIQFANYNLEVAKIETKLEFTQAFFQTAICKISLCTGLPW 121

Query: 370 LIK 372
           +++
Sbjct: 122 VLR 124


>UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger
           antiporter; n=1; Pirellula sp.|Rep: Probable
           sodium/calcium exchanger antiporter - Rhodopirellula
           baltica
          Length = 432

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 13/107 (12%)

Query: 18  PELFVNVIGTFITEG----DIGVGTIVGSAVFNILAVAACCGIGA-GMVVP--------L 64
           PELF  +I  F+        IG+GT  GSA+FN + + A C +   G VV         +
Sbjct: 52  PELFTTLIALFVLSDRDGFSIGIGTTAGSALFNGMIIPAVCILSVVGFVVMGVRVTSVNV 111

Query: 65  DWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 111
               L RD ++  +   ILI +I+ E + W++  +L+ +Y  Y+  M
Sbjct: 112 STRVLLRDGISLILCEFILILLINGEQLHWWQGLILMLMYATYLVYM 158


>UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:
           CG5685-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 950

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           +TF++ I  IG ++ I+    +  G  L I DSV  I F+A GTS+P+  +S+I AK   
Sbjct: 779 VTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDE 838

Query: 346 XXXX-XXXXXXXXTFDILLCLGLPWLIKA 373
                          ++ L +GL W I A
Sbjct: 839 GADNCIGNVTGSNAVNVFLGIGLAWTIAA 867



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 18/42 (42%), Positives = 27/42 (64%), Gaps = 3/42 (7%)

Query: 18  PELFVNVIGTFITE---GDIGVGTIVGSAVFNILAVAACCGI 56
           PE+ ++VI  +  +   GD+G GTIVGSA +N+  + A C I
Sbjct: 193 PEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMI 234


>UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1;
           Schizosaccharomyces pombe|Rep: Sodium/calcium exchanger
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 743

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 25/101 (24%), Positives = 54/101 (53%), Gaps = 2/101 (1%)

Query: 269 LFTIPDCEKP-RFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLA 326
           L+   D EKP +F  W   + F++ I+WI +++  V  ++  +G    + +S++G+T  A
Sbjct: 568 LYYYTDEEKPPKFLPWVSFIGFVLGIIWISTIANEVVGILRALGVIFNLNESILGLTVFA 627

Query: 327 AGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           AG S+ + ++ +++A+               T +IL+ +G+
Sbjct: 628 AGNSLSDLIADIMIARSGFPEMAMGGVFGGPTLNILIGIGI 668



 Score = 38.7 bits (86), Expect = 0.32
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 1/92 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F+   + I +  +    ++TI    L +PDSV+G+TFLA G   P+ +S+    +   
Sbjct: 119 LIFLFITIGISASDFFSTNLVTISW-LLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNS 177

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKASLTP 377
                        F + +  G   LIK    P
Sbjct: 178 GGMAIGELLGSAFFIVAIVAGSVCLIKPFKIP 209



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 16/96 (16%), Positives = 45/96 (46%), Gaps = 1/96 (1%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           P++        +  G + +G ++GSA F +  VA    +     +P   + L       G
Sbjct: 164 PDILSTFAAVRVNSGGMAIGELLGSAFFIVAIVAGSVCLIKPFKIPRRHF-LRDVAFLTG 222

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 113
             + +++ ++HD  +  +++ +++  Y +Y+  +++
Sbjct: 223 TILLVIMFVLHDGSLSIWQSLVMILYYLLYVLFVFF 258


>UniRef50_Q59GN4 Cluster: Solute carrier family 8 (Sodium/calcium
           exchanger), member 1 variant; n=24; Bilateria|Rep:
           Solute carrier family 8 (Sodium/calcium exchanger),
           member 1 variant - Homo sapiens (Human)
          Length = 411

 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)

Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
           ED+ D E G E    K PS   C   +   +T    ++F F +P  E   +  W    FI
Sbjct: 196 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 243

Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
           + I+ IG L+  +  + +  G T+ + DSV  + F+A GTSVP+  +S + A Q      
Sbjct: 244 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 303

Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
                      ++ L +G+ W I A
Sbjct: 304 SIGNVTGSNAVNVFLGIGVAWSIAA 328


>UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor
           (Na(+)/Ca(2+)-exchange protein 1); n=185;
           Euteleostomi|Rep: Sodium/calcium exchanger 1 precursor
           (Na(+)/Ca(2+)-exchange protein 1) - Homo sapiens (Human)
          Length = 973

 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)

Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
           ED+ D E G E    K PS   C   +   +T    ++F F +P  E   +  W    FI
Sbjct: 758 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 805

Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
           + I+ IG L+  +  + +  G T+ + DSV  + F+A GTSVP+  +S + A Q      
Sbjct: 806 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 865

Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
                      ++ L +G+ W I A
Sbjct: 866 SIGNVTGSNAVNVFLGIGVAWSIAA 890



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)

Query: 18  PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
           PE+ ++VI   G   T GD+G  TIVGSA FN+  + A C
Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186


>UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep:
           Zgc:153443 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 231

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 21/45 (46%), Positives = 29/45 (64%)

Query: 1   MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVF 45
           +++DV            PELF +VIG FI+  ++G+GTIVGSAVF
Sbjct: 167 ISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 18/34 (52%), Positives = 23/34 (67%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
           +T+I + L I D V G TF+AAG S PE  +SVI
Sbjct: 158 LTVITEKLEISDDVAGATFMAAGGSAPELFTSVI 191


>UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6;
           Trichocomaceae|Rep: Sodium/calcium exchanger protein -
           Aspergillus clavatus
          Length = 994

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 37/162 (22%), Positives = 70/162 (43%), Gaps = 6/162 (3%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F++ I WI +++  V  ++  +G  L I DS++G+T  A G S+ + V+ + VA+   
Sbjct: 833 LGFVVAIFWIATIATEVVSLLKTVGVILNISDSLLGLTVFAVGNSLGDLVADITVARLGY 892

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWL-IKASLTP----AEPGHYWVKINSMGLEYSAIXXX 400
                         +ILL +GL  L +  + TP       G Y + + S  L  S     
Sbjct: 893 PVMALSACFGGPMLNILLGIGLGGLYMTLNATPDTIATRTGSYEIAL-SKALIISGATLL 951

Query: 401 XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELN 442
                       N +++D  +G   + ++ +  +   + EL+
Sbjct: 952 ATLLLLLIIIPLNNWRMDRKIGWGLIVLWVISTVGNVIAELS 993


>UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1
           precursor (Na(+)/Ca(2+)-exchange protein 1).; n=1;
           Takifugu rubripes|Rep: Sodium/calcium exchanger 1
           precursor (Na(+)/Ca(2+)-exchange protein 1). - Takifugu
           rubripes
          Length = 900

 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 1/87 (1%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
           FI+CI  IG L+ I+  + +  G T+ + DSV  + F+A GTSVP+  +S + A Q    
Sbjct: 731 FIVCISIIGVLTAIIGDIASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVSAVQDQYA 790

Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
                        ++ L +G+ W I A
Sbjct: 791 DASIGNVTGSNAVNVFLGIGVAWSIAA 817


>UniRef50_UPI0000DB6F63 Cluster: PREDICTED: similar to solute
           carrier family 24 member 6; n=1; Apis mellifera|Rep:
           PREDICTED: similar to solute carrier family 24 member 6
           - Apis mellifera
          Length = 451

 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 2/113 (1%)

Query: 266 LVFLFTIPDCEKPRFKNWFPLT-FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITF 324
           +VFL T  D   P+F N F    F   ++ +  ++  V  ++  +G    I D+++GIT 
Sbjct: 260 IVFLITDKD-RIPKFHNAFAFFGFFTAMMVVYLVAKEVMAVLQCVGYAFSISDAMLGITL 318

Query: 325 LAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTP 377
           LA G S+ + +++V +A+Q               F+ LL LGL + ++A+  P
Sbjct: 319 LAWGNSIGDLIANVTIARQGFPRMGYAACFGGPMFNTLLGLGLTYGVEAAKDP 371


>UniRef50_Q2UDY9 Cluster: K+-dependent Na+:Ca2+ antiporter; n=1;
           Aspergillus oryzae|Rep: K+-dependent Na+:Ca2+ antiporter
           - Aspergillus oryzae
          Length = 785

 Score = 47.6 bits (108), Expect = 7e-04
 Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 6/161 (3%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L FI+ I WI +++  V  ++  +G  L I DS++G+T  A G S+ + V+ + VA+   
Sbjct: 624 LGFIVAICWIATIATEVVSLLKTLGVILNISDSLLGLTVFAVGNSLGDLVADITVARLGY 683

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWL-----IKASLTPAEPGHYWVKINSMGLEYSAIXXX 400
                         +ILL +GL  L      KA     +   Y + I+ + L  S     
Sbjct: 684 PVMALSACFGGPMLNILLGIGLGGLYMTLHAKAETVVTDGVPYEITISKV-LIISGATLL 742

Query: 401 XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIEL 441
                       NK+++D  VG   + ++ +  +   + E+
Sbjct: 743 STLVGLLIVVPLNKWRMDRKVGWGLVILWCISTLTNVIAEV 783


>UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family
           transporter precursor; n=1; Thiomicrospira crunogena
           XCL-2|Rep: Ca2+:cation antiporter (CaCA) family
           transporter precursor - Thiomicrospira crunogena (strain
           XCL-2)
          Length = 329

 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 2/107 (1%)

Query: 271 TIPDCEK-PRFKNWFPLTF-IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAG 328
           TI + E  P+  N   L F I+ +V +   + ++ W    I +   +P+ ++G+T +A G
Sbjct: 164 TIEEIEDLPKLSNQKALVFLILGLVVLMISAKMMVWGAVEIAEFFDVPEMIIGLTIVAIG 223

Query: 329 TSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASL 375
           TS+PE  +++  AK+               F++L  + +P LI  S+
Sbjct: 224 TSLPELAAAITAAKKGEADLMIGNILGSNLFNLLAVMSMPALIAPSV 270


>UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Rep:
           F7G19.17 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 546

 Score = 47.2 bits (107), Expect = 0.001
 Identities = 32/154 (20%), Positives = 70/154 (45%), Gaps = 3/154 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           + FIM + WI +++  +   +  +G  L +P +++G+T LA G SV + V+ V VAK   
Sbjct: 391 VAFIMSVFWISTIAGELLNCLAALGTLLKLPPALLGLTVLAWGNSVGDLVADVAVAKAGR 450

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXX 405
                        F++L+ LG   +++ +     P  Y +  + +G+  + +        
Sbjct: 451 PAMAMAGCFAGPMFNMLVGLGSALVMQTA--NVYPDAYKLGFH-VGIVIAFVFLLLSLMG 507

Query: 406 XXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
                 +++F++    G   + +Y  F  ++ +I
Sbjct: 508 SLLVITWSRFRVPRFWGICLVGLYVAFTFVSLII 541


>UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome
           shotgun sequence; n=10; Clupeocephala|Rep: Chromosome 10
           SCAF15123, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1007

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 1/87 (1%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
           FI+ I+ IG L+ ++  + +  G T+ + DSV  + F+A GTSVP+  +S + A Q    
Sbjct: 796 FIVSIIIIGLLTAVIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDMFASKVSAVQDAYA 855

Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
                        ++ L +G+ W + A
Sbjct: 856 DASIGNVTGSNAVNVFLGIGMAWSVAA 882


>UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 313

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 6/93 (6%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTR-DCLA- 75
           PEL  +++  +  + DI +G IVGS +FNIL +A  C     ++ P++   +   D L  
Sbjct: 217 PELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAGSC----SLIHPIEAKNVNYIDLLVM 272

Query: 76  YGITVSILICIIHDEYVQWYEAFLLVSLYGVYI 108
            GI+V +L  +   + +   E F+L+  Y +Y+
Sbjct: 273 LGISVLLLPLVKSGQKISRTEGFVLILFYVIYM 305



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 18/58 (31%), Positives = 30/58 (51%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           I   L + ++V+G+T +AAGTS+PE  +S++ A +               F+IL   G
Sbjct: 194 IAKELGVSEAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAG 251



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 16/30 (53%), Positives = 21/30 (70%)

Query: 18 PELFVNVIGTFITEGDIGVGTIVGSAVFNI 47
          PEL V++  T   +GDI +G IVGS +FNI
Sbjct: 52 PELVVSLNATLSGQGDIAIGNIVGSNIFNI 81


>UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium
           ion/calcium ion; n=2; Ostreococcus|Rep: CaCA family
           transporter: sodium ion/calcium ion - Ostreococcus
           lucimarinus CCE9901
          Length = 603

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 3/108 (2%)

Query: 35  GVGTIVGSAVFN-ILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQ 93
           G G  + S VF  ++ +A     G G+V  LD W   RD   Y +  ++ +    D  V+
Sbjct: 168 GAGAFIASFVFPCVVLIATRAASGRGLV--LDKWNFGRDVGFYAVASAMALGFFLDGRVE 225

Query: 94  WYEAFLLVSLYGVYICIMYYDKPIQNFAKGSWKWVSNMFKDNEEKQDA 141
            YEA  L SLY  Y+ ++   + ++ FA+     V     D++   D+
Sbjct: 226 AYEAAALFSLYAAYLFVLLSGRRLKRFARAVVALVRYGGDDSDSDSDS 273


>UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 1013

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 1/95 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F++ I WI +L+  V  ++  IG  L I DS++G+T  A G S+ + V+ V VA+   
Sbjct: 835 LGFLVSIAWISTLATEVVNVLKSIGVILSISDSLLGLTVFAVGNSLGDLVADVTVARLGY 894

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEP 380
                         +IL+ +G+  L   +L+P +P
Sbjct: 895 PVMALSACFGGPMLNILIGIGVGGLY-MTLSPNQP 928


>UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger protein;
           n=1; Clostridium tetani|Rep: Putative sodium/calcium
           exchanger protein - Clostridium tetani
          Length = 347

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           +   + ++W+ S+  I+    T+I     IP  ++ +  +AA TS+P+ + S+  ++   
Sbjct: 200 MAITIALIWV-SIDGIIQ-STTVISTFFNIPQYIVSVVIIAACTSIPDTLLSIKSSQDGD 257

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKASLTPA 378
                        FDI +CLG+P +I     PA
Sbjct: 258 VEGAVANAVGSNIFDICICLGVPIIIAGKTLPA 290



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 33  DIGVGTIVGSAVFNILAVAACCGI---GAGMVVPLDWWPLTRDCLAYGITVSILICIIHD 89
           D+GV TI GS VFNIL +         G  +++ +D   + RD + Y + +  L+   + 
Sbjct: 79  DVGVPTIAGSGVFNILIIPMATIFAYRGKDLLIKVDKKVVYRDMIFYTMAIGALVFFTYL 138

Query: 90  EYVQWYEAFLLVSLYGVYICIMY 112
                +   +LV +Y  YI ++Y
Sbjct: 139 GSYTVFAGIVLVLIYIGYIFVLY 161



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 283 WFPLTFIMCIVWIGS-LSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPE---AVSSV 338
           W  +  ++ + WI S  S  +   + I+G  L IP SV G TF A  +S PE   A+ +V
Sbjct: 12  WISIVMLIVMSWIISKASDKLGDALHILGVKLKIPTSVRGATFDAISSSFPEFSTAMIAV 71

Query: 339 IVAKQ 343
           IV K+
Sbjct: 72  IVYKR 76


>UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=3; Gammaproteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM
           17024)
          Length = 331

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 272 IPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSV 331
           IP+  +PR   WF +  I  ++     S I+ W      +   +   ++G+T +A GTS+
Sbjct: 170 IPEMSRPRAILWFAIGLIALMI----SSEILVWGAKTTAEYFSVSPLIIGLTVIAVGTSL 225

Query: 332 PEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPA 378
           PE  +SV+ A +               F++L  + +P +I   +  A
Sbjct: 226 PELAASVMSALKGHHDIALGNIIGSNIFNLLAVMAVPGIISPPIMEA 272



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 18/39 (46%), Positives = 24/39 (61%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 56
           PEL  +V+       DI +G I+GS +FN+LAV A  GI
Sbjct: 226 PELAASVMSALKGHHDIALGNIIGSNIFNLLAVMAVPGI 264


>UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
           Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family
           - Parvibaculum lavamentivorans DS-1
          Length = 334

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PE+  +V+  F  + DI +G +VGS +FN+L +A    +   + VP D      D    G
Sbjct: 240 PEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPVPVPADIAGF--DIWVMG 297

Query: 78  -ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 111
             ++  L+       +   EA LL+  YG Y+ ++
Sbjct: 298 AASLLFLVFAWTGSRIGRVEALLLLGGYGAYVTVL 332



 Score = 40.7 bits (91), Expect = 0.079
 Identities = 20/65 (30%), Positives = 34/65 (52%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
           + DSV+G+T +A GTS+PE  +SV+ A +               F++L   G+  ++K  
Sbjct: 223 VSDSVIGLTLVAVGTSLPEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPV 282

Query: 375 LTPAE 379
             PA+
Sbjct: 283 PVPAD 287


>UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related
           family protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
           K+-dependent Na+-Ca+ exchanger related family protein -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 325

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 23/73 (31%), Positives = 35/73 (47%)

Query: 299 SYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXT 358
           S I+ W    I   L I D ++G+T +A GTS+PE  SS++  ++               
Sbjct: 187 SRIMVWGAVSIAQALNISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALGNIVGSNI 246

Query: 359 FDILLCLGLPWLI 371
           F+ L  +GL  LI
Sbjct: 247 FNALAVVGLSGLI 259



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 6/68 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLA 75
           PEL  +++     + D+ +G IVGS +FN LAV       +G++ P    P  LTRD + 
Sbjct: 220 PELASSIVAVRKNQTDMALGNIVGSNIFNALAVVGL----SGLITPFAAEPEILTRDLVV 275

Query: 76  YGITVSIL 83
             I  ++L
Sbjct: 276 MTIVTAVL 283


>UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 737

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 1/87 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA-KQX 344
           +TF + + +IG L+ IV  + TI G  + + + V   TF+A GTS+P+  +S   A  + 
Sbjct: 647 VTFSVALCFIGILTAIVGDLATIFGCLVGLKNEVTAFTFVALGTSLPDLFASKAAAINEK 706

Query: 345 XXXXXXXXXXXXXTFDILLCLGLPWLI 371
                        + ++ L LG PW+I
Sbjct: 707 YADACIGNVTGSNSVNVFLGLGTPWVI 733



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 12/106 (11%)

Query: 18  PELFVNVIGTFITEG----DIGVGTIVGSAVFNILAVAACCGIG-----AGMVVPLDWWP 68
           PE+ +++I   I  G     +G  TIVGSA FN+L +   C +         +  ++ + 
Sbjct: 111 PEILLSIIEITIMNGFEAGALGPSTIVGSAAFNLLCITGVCVMAVPKFETRRIKSMNVFA 170

Query: 69  LT--RDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
           +T     LAY I + I++ +   + V+ +EA L    + + + I Y
Sbjct: 171 VTAITSLLAY-IWLFIILSVNTKDVVELWEAILTFLFFPILVIIAY 215


>UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 858

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 25/82 (30%), Positives = 42/82 (51%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F++ I WI +L+  V  ++  IG  L I DS++G+T  A G S+ + V+ + VA+   
Sbjct: 683 LGFVVSIAWISTLASEVVNLLKAIGVILSISDSLLGLTIFAVGNSLGDLVADITVARLGY 742

Query: 346 XXXXXXXXXXXXTFDILLCLGL 367
                         +ILL +G+
Sbjct: 743 PVMALSACFGGPMLNILLGVGM 764


>UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14779,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 880

 Score = 45.6 bits (103), Expect = 0.003
 Identities = 42/152 (27%), Positives = 67/152 (44%), Gaps = 11/152 (7%)

Query: 223 NLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKN 282
           +L  P+A  N   +D  E+   + PS   C   I   +T    ++F F +P  E   +  
Sbjct: 657 SLLHPSA--NLGDDDEEESGEERLPS---CFDYIMHFLTVFWKVLFAF-VPPTEY--WSG 708

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           W    F + I  IG L+ I   + +  G T+ + DSV  + F+A GTSVP+  +S + A 
Sbjct: 709 W--ACFFVSISLIGVLTAITGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAI 766

Query: 343 Q-XXXXXXXXXXXXXXTFDILLCLGLPWLIKA 373
           Q                 ++ L +G+ W I A
Sbjct: 767 QDQYADASIGNVTGSNAVNVFLGIGVAWTIAA 798


>UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3;
           Caenorhabditis|Rep: Sodium-calcium exchanger -
           Caenorhabditis elegans
          Length = 880

 Score = 45.6 bits (103), Expect = 0.003
 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 6/122 (4%)

Query: 253 LAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDT 312
           + K+   +  P  L+F   IP  +   F  W  L F++ I  IG L+  +  +    G T
Sbjct: 680 MEKVMHYIALPWKLLFAL-IPPTDY--FNGW--LCFVVAIAMIGLLTAFIGDIAAAFGCT 734

Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVA-KQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
           + + DSV  +T +A GTS+P+  +S   A                   ++ L +G+ W+I
Sbjct: 735 VGLKDSVTALTLVAMGTSLPDTFASRTAAVGDQWADGSIGNVTGSNAVNVFLGIGIAWMI 794

Query: 372 KA 373
            A
Sbjct: 795 AA 796



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%)

Query: 18  PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
           PE+ ++VI   G     G++G  TIVGSA FN+  + A C
Sbjct: 143 PEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVC 182


>UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2
           precursor (Na(+)/Ca(2+)-exchange protein 2).; n=1;
           Takifugu rubripes|Rep: Sodium/calcium exchanger 2
           precursor (Na(+)/Ca(2+)-exchange protein 2). - Takifugu
           rubripes
          Length = 953

 Score = 45.2 bits (102), Expect = 0.004
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 1/104 (0%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXX 347
           FI+ +V IG L+ I+  + +  G T+ + D+V  + F+A GTS+P+  +S   A Q    
Sbjct: 784 FIVSVVGIGFLTAIIGDVASHFGCTVGLRDTVTAVVFVALGTSLPDTFASKFAATQDQYA 843

Query: 348 XX-XXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSM 390
                        ++ L +GL W + A     + G + V   S+
Sbjct: 844 DACVGNVTGSNAVNVFLGIGLAWSVAAVYWKIKGGVFHVDPGSL 887



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%)

Query: 18  PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
           PE+ ++VI   G     G++G GTIVGSA FN+  +   C
Sbjct: 93  PEILLSVIEVCGHGFNAGELGPGTIVGSAAFNMFVIIGLC 132


>UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Firmicutes|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Clostridium
           perfringens (strain SM101 / Type A)
          Length = 331

 Score = 45.2 bits (102), Expect = 0.004
 Identities = 23/59 (38%), Positives = 35/59 (59%)

Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
           L + + ++G+T +A GTS+PE V+S++ AK+              TF+ILL LGL  LI
Sbjct: 213 LGLSEKLVGLTIVAIGTSLPELVTSLVAAKKGENDIALGNILGSNTFNILLILGLSSLI 271



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 17/45 (37%), Positives = 26/45 (57%)

Query: 18 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 62
          PEL V++        DI +G ++GS +FN+LA   C  I A +V+
Sbjct: 50 PELAVSISAALKGSNDITMGNVLGSNLFNLLAALGCTAIVAPLVI 94


>UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus
           ferrooxydans PV-1|Rep: Ca2+/Na+ antiporter -
           Mariprofundus ferrooxydans PV-1
          Length = 322

 Score = 45.2 bits (102), Expect = 0.004
 Identities = 25/86 (29%), Positives = 43/86 (50%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F++ +  +   S +V W    I   L + D ++G+T +A GTS+PE V+S++ A +  
Sbjct: 174 LWFVVGLALLIISSRMVVWGAVEIAHLLGVSDLIIGLTIVAIGTSLPELVASLVSALKGE 233

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLI 371
                        F++L  L +P LI
Sbjct: 234 ADLAIGNVIGSNMFNLLAVLAMPALI 259



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 9/102 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDC-LA 75
           PEL  +++     E D+ +G ++GS +FN+LAV A    I  G   P     L RD  + 
Sbjct: 220 PELVASLVSALKGEADLAIGNVIGSNMFNLLAVLAMPALIHPGAFAP---EALMRDFPIM 276

Query: 76  YGITVSILICII----HDEYVQWYEAFLLVSLYGVYICIMYY 113
            G T+++ +           +  +E  LL + +  Y+ ++Y+
Sbjct: 277 IGFTIALFVVSFALKKSGGVINRFEGGLLTAGFAGYLILLYF 318


>UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep:
           Slr0681 protein - Synechocystis sp. (strain PCC 6803)
          Length = 433

 Score = 44.8 bits (101), Expect = 0.005
 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 1/98 (1%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAY 76
           PEL  +V+ ++  E DI VG +VGS +FNILAV     I +   + +       D  + +
Sbjct: 292 PELATSVVASYRGERDIAVGNVVGSNIFNILAVLGFAAIFSPNGIQVSNSAFNFDIPVMF 351

Query: 77  GITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 114
            + +  L   I    +  +E FL +  Y  Y   +  D
Sbjct: 352 AVALVCLPVFITGRLIDRWEGFLFLFYYIAYTAYLVLD 389



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 15/45 (33%), Positives = 26/45 (57%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 62
           PE+ V++      + DI +G +VGS +FN+L +   C I   ++V
Sbjct: 119 PEMVVSLQAAIAGQADISIGNVVGSNIFNVLLILGVCSIITPLIV 163



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 20/58 (34%), Positives = 31/58 (53%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           I  +L I + V+G+T +AAGTS+PE  +SV+ + +               F+IL  LG
Sbjct: 269 IAKSLGISELVIGLTLIAAGTSLPELATSVVASYRGERDIAVGNVVGSNIFNILAVLG 326


>UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3;
           Flavobacteriales|Rep: Sodium/calcium exchanger -
           Robiginitalea biformata HTCC2501
          Length = 315

 Score = 44.8 bits (101), Expect = 0.005
 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 4/94 (4%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL-AY 76
           PEL  +VI     E  + VG ++GS +FN+LAV     I A + V LD   LTRD     
Sbjct: 218 PELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGLTAILAPVPV-LDDRLLTRDVFWML 276

Query: 77  GITVSILICIIHDEYVQ--WYEAFLLVSLYGVYI 108
           GI+  +L  +   + ++  W +  +L++ YG ++
Sbjct: 277 GISFLVLPLVFFPKGLRLGWRDGIVLLACYGAFL 310



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 293 VWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXX 352
           +W GS   +V    ++  D L + D V+GIT ++ GTS+PE  +SVI   +         
Sbjct: 181 LWAGS-ELLVRGATSLAAD-LGVSDRVIGITVVSVGTSIPELAASVIAMAKREKAMSVGN 238

Query: 353 XXXXXTFDILLCLGL 367
                 F++L  LGL
Sbjct: 239 LIGSNIFNLLAVLGL 253


>UniRef50_Q8KU52 Cluster: EF0109; n=1; Enterococcus faecalis|Rep:
           EF0109 - Enterococcus faecalis (Streptococcus faecalis)
          Length = 1924

 Score = 44.4 bits (100), Expect = 0.006
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 8/103 (7%)

Query: 134 DNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKI-----LESVD 188
           D  +  + EN K+   S+  +  +  IE  +Q N   KTS + QD  + +     ++ V+
Sbjct: 84  DGTKISNGENSKETTTSSGTILAEEAIESSNQKNS--KTSEVEQDLHKDVSGSESVKQVE 141

Query: 189 VSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAED 231
            SD +  SEE   K +N+D DS+ N   I +  EN    T  D
Sbjct: 142 TSDSIKKSEESAVKTLNLD-DSQENTNSITTKAENDALSTVND 183


>UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Reinekea sp. MED297|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Reinekea sp. MED297
          Length = 321

 Score = 44.4 bits (100), Expect = 0.006
 Identities = 25/79 (31%), Positives = 36/79 (45%)

Query: 301 IVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFD 360
           ++ W    I D   I ++V+G T +A GTS+PE  +SV  A +               F+
Sbjct: 188 VLVWGAVGIADMFQISEAVIGATIIAVGTSLPELAASVASALKKHHDIAIGNVLGSNIFN 247

Query: 361 ILLCLGLPWLIKASLTPAE 379
           IL  L +P LI      AE
Sbjct: 248 ILAVLSVPGLIAPGAFDAE 266



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 16/39 (41%), Positives = 23/39 (58%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 56
           PEL  +V        DI +G ++GS +FNILAV +  G+
Sbjct: 219 PELAASVASALKKHHDIAIGNVLGSNIFNILAVLSVPGL 257



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 15/63 (23%), Positives = 31/63 (49%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           + + L +P  ++G+T ++ GTS PE ++++  A +                +I L LG+ 
Sbjct: 29  LANNLGVPHLIIGVTIVSLGTSAPEIIAAIFAALEGRIELAMGNAIGSNVANIGLVLGIT 88

Query: 369 WLI 371
            L+
Sbjct: 89  ALV 91


>UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; Mycobacterium|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 335

 Score = 44.4 bits (100), Expect = 0.006
 Identities = 25/108 (23%), Positives = 49/108 (45%), Gaps = 1/108 (0%)

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           +F +T +   V +    ++V   + I  +   + D+++G+T +A GTS PE V++++   
Sbjct: 188 YFAMTIVGITVVVVGADWLVEGAVGIARE-FGVSDALIGLTIVAIGTSAPELVTTIVSTV 246

Query: 343 QXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSM 390
           +               ++I+L LG   L+ A   P      W+ I  M
Sbjct: 247 RGERDIAIGNLLGSSVYNIVLILGATCLVPADGLPLNSSLVWIDIPVM 294



 Score = 42.7 bits (96), Expect = 0.020
 Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 5/70 (7%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL   ++ T   E DI +G ++GS+V+NI+ +     +GA  +VP D  PL    +   
Sbjct: 236 PELVTTIVSTVRGERDIAIGNLLGSSVYNIVLI-----LGATCLVPADGLPLNSSLVWID 290

Query: 78  ITVSILICII 87
           I V ++  ++
Sbjct: 291 IPVMVVATLL 300


>UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor
           (Na(+)/Ca(2+)-exchange protein 3); n=109; Eumetazoa|Rep:
           Sodium/calcium exchanger 3 precursor
           (Na(+)/Ca(2+)-exchange protein 3) - Homo sapiens (Human)
          Length = 927

 Score = 44.4 bits (100), Expect = 0.006
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
           F + I+ IG L+ I+  + +  G T+ + DSV  + F+A GTSVP+  +S   A Q    
Sbjct: 758 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 817

Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
                        ++ L +GL W + A
Sbjct: 818 DASIGNVTGSNAVNVFLGIGLAWSVAA 844


>UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=2; Chlorobiaceae|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Chlorobium phaeobacteroides BS1
          Length = 325

 Score = 44.0 bits (99), Expect = 0.008
 Identities = 24/87 (27%), Positives = 44/87 (50%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +++ TF  + DI VG +VGS +FN+L V   C     + VP++        +   
Sbjct: 229 PELVTSLVATFQGKTDIAVGNVVGSNIFNLLLVNGVCSSITQIAVPVNGGFYDLFMMILL 288

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLY 104
               + + I H + +  +E  +L+++Y
Sbjct: 289 AVFLLPMSITHKKKIVRWEGAVLLAMY 315



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 23/75 (30%), Positives = 35/75 (46%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           I + L IP  ++G+T +A GTS+PE V+S++   Q               F++LL  G+ 
Sbjct: 206 IAEALEIPQVIIGLTVVAIGTSLPELVTSLVATFQGKTDIAVGNVVGSNIFNLLLVNGVC 265

Query: 369 WLIKASLTPAEPGHY 383
             I     P   G Y
Sbjct: 266 SSITQIAVPVNGGFY 280


>UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2;
           Caenorhabditis|Rep: Na/ca exchangers protein 10 -
           Caenorhabditis elegans
          Length = 668

 Score = 44.0 bits (99), Expect = 0.008
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 1/79 (1%)

Query: 266 LVFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITF 324
           L   FT  D E+  ++  +  L F+M I WI ++S  +  +IT+IG    +   ++G+T 
Sbjct: 474 LALRFTPLDREQKYYREVYSYLGFLMSIAWIYTISSEIINVITMIGVATGVSQEILGLTI 533

Query: 325 LAAGTSVPEAVSSVIVAKQ 343
           +A    + + VS V V KQ
Sbjct: 534 MAWSNCIGDIVSDVAVVKQ 552


>UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_11,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 498

 Score = 44.0 bits (99), Expect = 0.008
 Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
           I+ +VWI  LS I+   +T  G    + ++ +G+T +A G ++P+ + ++ +AKQ     
Sbjct: 338 IVSLVWIYCLSGILIDTLTFFGMLTNLSNTYLGMTIIAMGNALPDGIVTMTLAKQGYAVM 397

Query: 349 XXXXXXXXXTFDILLCLGLPWLIKASL 375
                     F +L+ LG+  L+K +L
Sbjct: 398 GITGAYFGQIFGLLVGLGIS-LLKTNL 423


>UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4;
           Methanosarcinaceae|Rep: Sodium/calcium exchanger protein
           - Methanosarcina acetivorans
          Length = 350

 Score = 44.0 bits (99), Expect = 0.008
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 281 KNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIV 340
           K+ F L      + IG+  Y V   I    + L IPD+V+G T +A GTS+PE V +V  
Sbjct: 206 KDIFTLVLSCAAIVIGA-KYFVEESI-FFAELLGIPDTVIGTTLVAVGTSLPELVVTVSA 263

Query: 341 AKQXXXXXXXXXXXXXXTFDILLCLGLPWL 370
           A+Q                +I L LGL  L
Sbjct: 264 ARQGYGSIALGNVIGSNITNIFLILGLSGL 293



 Score = 34.7 bits (76), Expect = 5.2
 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 3/97 (3%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM-VVPLDWWPLTRDCLAY 76
           PEL V V       G I +G ++GS + NI  +    G+   + V  +  +  T   +A 
Sbjct: 255 PELVVTVSAARQGYGSIALGNVIGSNITNIFLILGLSGLFYPLSVAEMSLFFTTPVMIA- 313

Query: 77  GITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 113
            I++ +LI I     ++ +E  +L+  Y  ++ +++Y
Sbjct: 314 -ISLILLIFISTGWEIKRWEGVVLMMFYVAFLVVLFY 349


>UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 996

 Score = 43.6 bits (98), Expect = 0.011
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 269 LFTIPDCEKPRFKNWFPLT-FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAA 327
           L T      P+++N      F + I WI +++  V  ++  +G  L + D+++G+T  A 
Sbjct: 805 LITTSPNRPPKWRNLLCFVGFAVAIAWISTIANEVVGVLRTLGVILNMSDAILGLTIFAV 864

Query: 328 GTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           G S+ + V+ + VA+                 +ILL +GL
Sbjct: 865 GNSLGDLVADITVARLGFPIMALSACFGGPMLNILLGIGL 904


>UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF10698,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 793

 Score = 43.2 bits (97), Expect = 0.015
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
           F++ I  IG L+ I+  + +  G T+ + DSV  + F+A GTSVP+  +S + A Q    
Sbjct: 624 FMVSISIIGVLTAIIGDIASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVSAVQDQYA 683

Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
                        ++ L +G+ W I A
Sbjct: 684 DASIGNVTGSNAVNVFLGIGVAWSIAA 710


>UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyces
           pombe CaCA sodium/calcium exchanger; n=1; Yarrowia
           lipolytica|Rep: Similar to tr|P87122 Schizosaccharomyces
           pombe CaCA sodium/calcium exchanger - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 812

 Score = 43.2 bits (97), Expect = 0.015
 Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 2/103 (1%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXX 347
           F+  I W+  ++ +V  ++  +G  L I D V+G+T  A G S+ + +++  +AK     
Sbjct: 659 FLTSIAWVSHIADVVVGVLKALGAILGISDPVLGLTVFAFGNSLGDLIANTTIAKMGFPM 718

Query: 348 XXXXXXXXXXTFDILLCLGLPWLIKASL--TPAEPGHYWVKIN 388
                       ++L+ +G+  LI  S      + G Y ++I+
Sbjct: 719 MALSACFGGPLLNVLVGVGVSGLIVTSSPGNAVKNGSYHIEIS 761


>UniRef50_Q2HE40 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 221

 Score = 43.2 bits (97), Expect = 0.015
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)

Query: 269 LFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAA 327
           L T    +KPR+      L FI+ + WI +++  V  ++  +G  L I ++++G+T  A 
Sbjct: 17  LATTTPHKKPRYHFLLCFLGFIISVAWISTIAGEVVGVLKALGVILGISEAILGLTVFAV 76

Query: 328 GTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           G S+ + V+ V VA+                 +ILL +G+
Sbjct: 77  GNSLGDLVADVTVARLGYPVMALAASVGGPMLNILLGVGI 116


>UniRef50_Q4RST3 Cluster: Chromosome 12 SCAF14999, whole genome
            shotgun sequence; n=6; Deuterostomia|Rep: Chromosome 12
            SCAF14999, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1206

 Score = 42.7 bits (96), Expect = 0.020
 Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 7/118 (5%)

Query: 266  LVFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITF 324
            +VF  T  D   P+++  F  L F++  V I + +  V  ++ ++G  L + ++V+G+T 
Sbjct: 1005 IVFCSTTND-RPPKYQPVFAVLGFMVSAVLISAAASEVVSLLHMLGVVLSLSNTVLGLTL 1063

Query: 325  LAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLC----LGLPWLIKASLTPA 378
            LA G S+ +  S + +A+Q               F IL+      G P L  A+LTPA
Sbjct: 1064 LAWGNSIGDCFSDITIARQGYPRMAISACFGGIVFSILVSTRPRAGRPSL-AATLTPA 1120


>UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane region;
           n=1; Pseudoalteromonas atlantica T6c|Rep: Sodium/calcium
           exchanger membrane region - Pseudoalteromonas atlantica
           (strain T6c / BAA-1087)
          Length = 171

 Score = 42.7 bits (96), Expect = 0.020
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD--WWPLTRDCLA 75
           PELFV+V      + DI +G ++G  + N+L +   C     M++PL      L RD L 
Sbjct: 20  PELFVSVNAALNNQPDIAIGNVIGRNIANVLLILGLC----AMIMPLTVATISLRRDALV 75

Query: 76  YGITVSILICIIHDEYV-QWYEAFLLVSLYGVYICIMYYDKPIQN 119
             +  S+L   +  E V  + E   L+     Y+   Y  K  Q+
Sbjct: 76  V-VAASVLCIALSSEGVTSFVEGLFLLGALAAYLTWTYLSKKGQS 119


>UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 320

 Score = 42.3 bits (95), Expect = 0.026
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 302 VAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDI 361
           V W  + I  TL + D V+G+T +A GTS+PE  +SV  A +               F++
Sbjct: 186 VVWGASEIASTLGVSDLVIGLTVVAIGTSLPELAASVASALRGEDAMAIGNVLGSNVFNL 245

Query: 362 LLCLGLPWLIKASLTPAEPGH 382
           L  L  P    A L P E  H
Sbjct: 246 LAVLPFP----AFLDPGEIDH 262


>UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger protein;
           n=1; marine gamma proteobacterium HTCC2080|Rep: Putative
           sodium/calcium exchanger protein - marine gamma
           proteobacterium HTCC2080
          Length = 321

 Score = 42.3 bits (95), Expect = 0.026
 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)

Query: 293 VWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXX 352
           V IGS   +V W    I ++  + + V+G+T +A GTS+PE  +S++ A +         
Sbjct: 177 VLIGSSKALV-WAAVNIAESYGVSELVIGLTIIALGTSLPELAASMVSAIKGHADIAIGA 235

Query: 353 XXXXXTFDILLCLGLPWL 370
                 F++L+ L +P L
Sbjct: 236 VVGSNMFNLLIVLAIPGL 253



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 10/105 (9%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +++       DI +G +VGS +FN+L V A  G+ + +   L    L RD     
Sbjct: 215 PELAASMVSAIKGHADIAIGAVVGSNMFNLLIVLAIPGLFSPL--ELSTTDLQRDLGTVF 272

Query: 78  ITVSILICII--------HDEYVQWYEAFLLVSLYGVYICIMYYD 114
           +T + L   +            +      L +S Y VY   +YYD
Sbjct: 273 VTTAALAVFVGFGWRKEKSHARLGRMAGCLFLSSYVVYCLWLYYD 317


>UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis
           thaliana|Rep: AT5g17860/MVA3_210 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 570

 Score = 42.3 bits (95), Expect = 0.026
 Identities = 40/156 (25%), Positives = 66/156 (42%), Gaps = 6/156 (3%)

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA- 341
           W    F M + W   ++  +  ++  +G+   I  SV+G+T LA G S+ + +++V VA 
Sbjct: 405 WLLGGFTMSVTWTYMIAQELVSLLISLGNIFGISPSVLGLTVLAWGNSLGDLIANVTVAF 464

Query: 342 --KQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXX 399
                              F+ ++ LG+P L+ +SL    PG Y +  ++  LE      
Sbjct: 465 HGGNDGAQIALSGCYAGPLFNTVIGLGVP-LVISSLA-EYPGVYIIPSDNSLLETLGF-L 521

Query: 400 XXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLIL 435
                         K +LD  VG   LA+Y  FL L
Sbjct: 522 MVGLLWALVIMPKKKMRLDKLVGGGLLAIYLCFLSL 557


>UniRef50_Q9VC56 Cluster: CG5794-PD, isoform D; n=7; Eukaryota|Rep:
            CG5794-PD, isoform D - Drosophila melanogaster (Fruit
            fly)
          Length = 3912

 Score = 42.3 bits (95), Expect = 0.026
 Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 11/116 (9%)

Query: 136  EEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSA 195
            EEK +AE    ++ S+  +K DV +E   +     K +    ++KE   +  +++D  S 
Sbjct: 2403 EEKSEAEEPTKMETSSSEIKADVDVEVEVEEKDKEKPAQTDTESKETPAKE-EIADDKSK 2461

Query: 196  SEEGKDKNV---------NIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENS 242
             +E ++K +           + D KP EM   S EE   QPTA  +   ++ + NS
Sbjct: 2462 QDEPEEKKIEKQSREGEEKSETDEKPTEMTTVSTEEE-KQPTANCDNHQQNNNSNS 2516


>UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na/Ca
           exchanger - Aedes aegypti (Yellowfever mosquito)
          Length = 583

 Score = 42.3 bits (95), Expect = 0.026
 Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 3/164 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F+  I  I  ++  V  ++  +G  L +  S++G++ LA G S+ +  S++ +AK+  
Sbjct: 413 LAFVGSIQVIYVVAQEVVSLLMTLGLVLELSKSMLGLSVLAWGNSIGDLFSNIALAKRGY 472

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXX 405
                        F++ L LG   +++AS         + +  +MG E            
Sbjct: 473 GKMAFAACFGGPLFNLCLGLGSTMIVRASKKKDHVA--FSREGAMG-ENCEWFLVQLLAT 529

Query: 406 XXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNV 449
                    F+   ++G   + +Y MFL+  TL EL V  P  +
Sbjct: 530 ILFVLMLTGFQGRRSLGLIMIIIYLMFLLFCTLGELEVIDPFGI 573


>UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 1060

 Score = 42.3 bits (95), Expect = 0.026
 Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 4/118 (3%)

Query: 277 KPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVS 336
           K RF   F + F++ I WI +++  V  ++   G  L I D+++G+T  A G S+ + V+
Sbjct: 872 KHRFVLCF-VGFVVAIAWISTIANEVVGVLKAFGVILGISDAILGLTIFAVGNSLGDLVA 930

Query: 337 SVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEY 394
            + VA+                 +IL+ +G+     A +T  E  H   K  +  ++Y
Sbjct: 931 DITVARLGYPVMALSACFGGPMLNILIGIGVS---GAYMTIKEANHKHHKHPNKDIKY 985


>UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2;
           Sordariomycetes|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 1004

 Score = 42.3 bits (95), Expect = 0.026
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 1/107 (0%)

Query: 277 KPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAV 335
           +PR+   F  L FI+ + WI +++  V  ++   G  L I ++++G+T  A G S+ + V
Sbjct: 821 RPRYHFLFCFLGFIISVAWISTVAGEVVGVLKAFGVILGISEAILGLTIFAVGNSLGDLV 880

Query: 336 SSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGH 382
           + + VA+                 +ILL +G+      + T  E  H
Sbjct: 881 ADITVARLGYPVMALAACFGGPMLNILLGIGIGGAWMTTKTANERHH 927


>UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep:
           Uvs037 - uncultured bacterium
          Length = 354

 Score = 41.9 bits (94), Expect = 0.034
 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 15/102 (14%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PE+  +V+ T   E DI VG +VGS +FNIL V    GI +G+V P+   PL       G
Sbjct: 218 PEVVTSVVATIKGERDIAVGNVVGSNIFNILCV---LGI-SGLVSPI---PLLAGEQLAG 270

Query: 78  ITVSIL-----ICI---IHDEYVQWYEAFLLVSLYGVYICIM 111
             + ++     +C+        +   E FL ++LY  Y+ I+
Sbjct: 271 FDIPVMLGVAALCVPLFFVGAILNRMEGFLFLTLYVAYVWIL 312



 Score = 39.9 bits (89), Expect = 0.14
 Identities = 19/57 (33%), Positives = 32/57 (56%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
           + ++V+G+T +AAGTS+PE V+SV+   +               F+IL  LG+  L+
Sbjct: 201 VNEAVIGLTIVAAGTSLPEVVTSVVATIKGERDIAVGNVVGSNIFNILCVLGISGLV 257



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 20/57 (35%), Positives = 26/57 (45%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
           +P  V+G+T +A GTS PE   SV  A                 F+IL  LG+  LI
Sbjct: 33  VPALVIGLTVVAFGTSAPELAVSVKAAFSGQAELAIANVVGSNIFNILFILGVAALI 89



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL V+V   F  + ++ +  +VGS +FNIL +     + + +++      L R  +   
Sbjct: 50  PELAVSVKAAFSGQAELAIANVVGSNIFNILFILGVAALISPLIIS---HQLIRQDVPIM 106

Query: 78  ITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYICIMYY 113
           + VSI+ + +  D  +   EA +L      Y   ++Y
Sbjct: 107 VGVSIVAVLMTLDGNINKLEASILTIGLISYTWFLFY 143


>UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
           Thermotogaceae|Rep: Na+/Ca+ antiporter, CaCA family -
           Thermosipho melanesiensis BI429
          Length = 311

 Score = 41.9 bits (94), Expect = 0.034
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PE+ V++I T   E DI VG IVGS +FNIL +     +   + V  D    T D +   
Sbjct: 215 PEIVVSIISTLKNEADILVGNIVGSNIFNILFILGVSSLVGNLYV--DVQNFTIDLIIMN 272

Query: 78  ITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYI 108
           + V IL    +  + +   E    +++Y  YI
Sbjct: 273 LFVFILFFTSLLRKKIGKVEGIFFLTIYVFYI 304



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 293 VWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXX 352
           +W+G    +    +  +  +L + ++ +G+T +A GTS+PE V S+I   +         
Sbjct: 178 IWLGG--DLTIGNVIKLAKSLGLSETFVGLTIVAIGTSLPEIVVSIISTLKNEADILVGN 235

Query: 353 XXXXXTFDILLCLGLPWLI 371
                 F+IL  LG+  L+
Sbjct: 236 IVGSNIFNILFILGVSSLV 254


>UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=3; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Stappia aggregata
           IAM 12614
          Length = 337

 Score = 41.9 bits (94), Expect = 0.034
 Identities = 24/66 (36%), Positives = 34/66 (51%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           I   L IP+ V+G+T +A GTS PE V S+  A +                ++LL LG+P
Sbjct: 29  IAQRLGIPNLVIGLTIVAFGTSAPELVISLKAALEGAGGIAIGNVVGSNIANVLLVLGMP 88

Query: 369 WLIKAS 374
            LI A+
Sbjct: 89  ALIAAT 94



 Score = 38.7 bits (86), Expect = 0.32
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP-----LDWWPLTRD 72
           PEL   V+      G + +G ++GS VFN+LA+     +   + VP     LD W +   
Sbjct: 238 PELATTVMAAIRQHGAVAIGNVIGSNVFNLLAIIGITAVIVPIDVPQEVLKLDIWVMLAC 297

Query: 73  CLAYGITVSILICI 86
            +   I   + IC+
Sbjct: 298 AILLTILAGMRICL 311



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 1/98 (1%)

Query: 283 WFPLTFIMC-IVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA 341
           W  L +I+  +V +   ++      T I  +  + ++V+G+T +A GTS+PE  ++V+ A
Sbjct: 188 WIALAYIVLGLVGLPLGAHFTISGATSIATSWGVSEAVIGLTVIALGTSLPELATTVMAA 247

Query: 342 KQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
            +               F++L  +G+  +I     P E
Sbjct: 248 IRQHGAVAIGNVIGSNVFNLLAIIGITAVIVPIDVPQE 285


>UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 974

 Score = 41.9 bits (94), Expect = 0.034
 Identities = 17/55 (30%), Positives = 37/55 (67%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           FI  ++WI +++  V  +++ +G+ L + D+++G+T  A G S+ + V++V VA+
Sbjct: 819 FICSMMWIAAIADEVVDVLSTLGEILGLSDAIIGLTIFAVGNSLADLVANVTVAQ 873



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 6/93 (6%)

Query: 23  NVIGTF--ITEGDIG--VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGI 78
           +V  TF  ++ G +G  VG ++G+A F +  V           VP +     RD + + I
Sbjct: 132 DVFSTFSAMSSGTLGLAVGELIGAASFIVSIVVGSIAFIRPFHVPKN--AFRRDVIFFTI 189

Query: 79  TVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 111
            V +LI  +HD ++ + E+  +V LY VY+ ++
Sbjct: 190 AVLMLIVALHDGHLTFAESGSMVGLYVVYVGVV 222


>UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter
           thermautotrophicus|Rep: ORF318 - Methanobacterium
           thermoformicicum
          Length = 160

 Score = 41.9 bits (94), Expect = 0.034
 Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 2/72 (2%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           + D   IP  +MG+  LA GTS+PE V ++  A +              TF+IL+ +G+P
Sbjct: 39  LADIAGIPAMIMGLFTLAIGTSIPELVVTLSSAVKGLHELSIGTVLGSNTFNILVGIGVP 98

Query: 369 WLIKASLTPAEP 380
            LI  +  P EP
Sbjct: 99  ALI--APVPVEP 108


>UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Na+/Ca+
           antiporter, CaCA family - Halorubrum lacusprofundi ATCC
           49239
          Length = 326

 Score = 41.9 bits (94), Expect = 0.034
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL V V       G+IGVG I+GS  +N+  +     +    V+P++   + RD  A  
Sbjct: 57  PELVVTVDAALAGLGEIGVGNIIGSNAYNLAFILG--AVSLLRVIPVERSLVHRDGAALV 114

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 115
           ++  +    + D  V   E  LL  L+  Y   +  D+
Sbjct: 115 LSTLVGAAALFDRTVTGVEGALLAGLFVAYTAYLVRDE 152


>UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum
           symbiosum|Rep: Ca2 /Na antiporter - Cenarchaeum
           symbiosum
          Length = 294

 Score = 41.9 bits (94), Expect = 0.034
 Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 292 IVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXX 351
           +  +G+ +++      ++     + + V+G T +A GTS+PE V+SV+  K+        
Sbjct: 161 VALLGAGAWLAVENAVVLARAFGLSEMVIGTTVIAIGTSLPELVTSVVAIKRGHTDIGVG 220

Query: 352 XXXXXXTFDILLCLGLPWLIKASLTPAEPG 381
                  ++IL+ +G+  +I A   P  PG
Sbjct: 221 NIIGSNIYNILMIMGVASMIAA--VPVAPG 248



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 17/45 (37%), Positives = 25/45 (55%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 62
           PEL  +V+       DIGVG I+GS ++NIL +     + A + V
Sbjct: 201 PELVTSVVAIKRGHTDIGVGNIIGSNIYNILMIMGVASMIAAVPV 245


>UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3;
           Poaceae|Rep: K-exchanger-like protein - Sorghum bicolor
           (Sorghum) (Sorghum vulgare)
          Length = 573

 Score = 41.5 bits (93), Expect = 0.045
 Identities = 20/59 (33%), Positives = 35/59 (59%)

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA 341
           W    F+M ++W  +L+  +  ++  IG  + I  SV+G+T LA G S+ + VS+V +A
Sbjct: 411 WLAAGFVMSVLWAYTLARELVALLVSIGYVVGIKPSVLGVTVLAWGDSLGDLVSNVAMA 469



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 18  PELFVNVIGTFITEGD-IGVGTIVGSAVFNILAVAACCGIGAGMV---VPLDWWPLTRDC 73
           P++F +V+     +G  +G+ + +G A+F    VA    +  G     V ++W    RD 
Sbjct: 161 PDVFASVVSFASGDGGGVGLSSALGGALFVSTVVAGVVALAVGGARGGVVVEWRGFVRDL 220

Query: 74  LAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
               + +  L+ ++ +  +  + A   VSLY  Y+ +++
Sbjct: 221 CFLLLALCYLLAVLVNGVITVWVAVSFVSLYVGYVVLVW 259


>UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein
           B14D6.440; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein B14D6.440 - Neurospora crassa
          Length = 898

 Score = 41.5 bits (93), Expect = 0.045
 Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 1/77 (1%)

Query: 267 VFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFL 325
           + L T    +KP++      L F++ I WI +++  V  ++   G  L I ++++G+T  
Sbjct: 738 ILLLTTRADKKPKYHFLLCFLGFVISIAWISTIANEVVGILKAFGVILGISEAILGLTIF 797

Query: 326 AAGTSVPEAVSSVIVAK 342
           A G S+ + V+ V VA+
Sbjct: 798 AVGNSLGDLVADVTVAR 814


>UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 386

 Score = 41.5 bits (93), Expect = 0.045
 Identities = 21/93 (22%), Positives = 46/93 (49%)

Query: 278 PRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSS 337
           PR   +  +  I+ ++ +    YI++  +T +  +L +  +V+G T L+  T++PE + +
Sbjct: 236 PRSTLYHSVHLILGLLALSLSGYILSHSLTSLATSLSLSTNVLGTTILSIATTLPEKLVA 295

Query: 338 VIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWL 370
           ++  K+              TF + LC G+ +L
Sbjct: 296 ILSGKRRQGGIIVANTVGSNTFLLTLCAGILFL 328


>UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Putative
           uncharacterized protein - Candidatus Kuenenia
           stuttgartiensis
          Length = 318

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 9/95 (9%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL ++ +  F  E DI VG ++GS ++NILAV    GI A ++ PL    +    L + 
Sbjct: 220 PELAISTVAAFRKESDICVGNVLGSNIYNILAV---LGITA-IIHPLQ---INTSSLQFD 272

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
           + V I+  ++    +     F+L    GV++ + Y
Sbjct: 273 MPVMIVFSLLLIPMIM--RKFILTRWEGVFLLVGY 305


>UniRef50_A5Z8F4 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 1054

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 4/112 (3%)

Query: 131 MFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVS 190
           + K +EEK+D  N  D++   H L+    ++    ++       +R+  KE   E  D  
Sbjct: 429 VMKSDEEKEDILNVDDVEDILHQLQARGILKAETVNSAVSIIENVRETKKESKEEKPDEK 488

Query: 191 DKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENS 242
           D VS  +  ++ NV +D   KP E E  S E+N      ++ T VED + ++
Sbjct: 489 D-VSTLDRWQEDNVEVD---KPLEKEQTSVEDNTSDNEEKEQTSVEDNTSDN 536


>UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Petrotoga mobilis SJ95|Rep: Na+/Ca+ antiporter, CaCA
           family - Petrotoga mobilis SJ95
          Length = 320

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 20/67 (29%), Positives = 36/67 (53%)

Query: 308 IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           I   ++ I +S++G+T +A GTS+PE V++++ A +              TF+I   LG+
Sbjct: 199 IFAKSIGISESLIGVTIVAVGTSLPELVTAIVAAIKHSDDIVMGNIVGSNTFNIAAILGI 258

Query: 368 PWLIKAS 374
             LI  +
Sbjct: 259 SALINGA 265


>UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein
           precursor; n=5; Proteobacteria|Rep: Na+/Ca+ antiporter,
           CaCA family protein precursor - Psychromonas ingrahamii
           (strain 37)
          Length = 326

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 22/83 (26%), Positives = 41/83 (49%)

Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
           I+ IV + + S ++ W    +     + D ++G+T +A GTS+PE  +++  A++     
Sbjct: 180 IIGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDL 239

Query: 349 XXXXXXXXXTFDILLCLGLPWLI 371
                     F+IL  + LP LI
Sbjct: 240 AVGNIIGSNIFNILGVMALPGLI 262



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 56
           PEL   +      E D+ VG I+GS +FNIL V A  G+
Sbjct: 223 PELAATIAAARKKEFDLAVGNIIGSNIFNILGVMALPGL 261


>UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2;
           Oscillatoriales|Rep: Sodium-calcium exchanger - Lyngbya
           sp. PCC 8106
          Length = 315

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 24/90 (26%), Positives = 41/90 (45%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F++ ++ +   S I       IG +L     ++G+T +A GTS+PE VSS+    Q  
Sbjct: 9   LVFVVSLIVLIKFSDIFTETAGKIGVSLGFSPFIVGVTIVAIGTSLPELVSSIFAVYQGA 68

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKASL 375
                         +I L +G+  L+ + L
Sbjct: 69  TEIVASNVIGSNVANIFLIIGVATLLSSPL 98



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL V    +   + ++ +G ++GS +FN L V    G+   +++P D   + RD L   
Sbjct: 220 PELAVTFSASRRGDAEVAIGNVLGSNIFNSLIVMGVPGLFEDLIIP-D--IIIRDGLPML 276

Query: 78  ITVSILICII-HDEYVQWYEAFLLVSLYGVYI 108
           +  ++L   +  D+ V  +E +L   LY  +I
Sbjct: 277 LASTLLFFFVTQDKKVTKWEGWLFFVLYAWFI 308


>UniRef50_Q6JAE1 Cluster: Putative K-exchanger-like protein; n=1;
           Zea mays|Rep: Putative K-exchanger-like protein - Zea
           mays (Maize)
          Length = 516

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 20/59 (33%), Positives = 34/59 (57%)

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA 341
           W    F+M ++W  +L+  +  ++  IG    I  SV+G+T LA G S+ + VS+V +A
Sbjct: 354 WLAAGFVMSVLWAYTLARELVALLVAIGYVAGIKPSVLGVTVLAWGDSLGDLVSNVAMA 412


>UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3;
           Caenorhabditis|Rep: Na/ca exchangers protein 8 -
           Caenorhabditis elegans
          Length = 703

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 20/89 (22%), Positives = 44/89 (49%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L F+M I WI + +  +  ++T++G    +   ++G+T ++    + + V+ + V KQ  
Sbjct: 547 LGFLMSIAWIYATANEIISVMTMVGVVTGLSQELLGLTVMSWSDCIGDIVADIAVIKQGY 606

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
                        F++L+  GLP+ I ++
Sbjct: 607 PKMAMAAAIGGPLFNLLIGFGLPFTIASA 635


>UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4;
           Halobacteriaceae|Rep: Na+/Ca2+-exchanging protein -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 344

 Score = 41.1 bits (92), Expect = 0.060
 Identities = 22/66 (33%), Positives = 34/66 (51%)

Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
           +T +  T  IP  + G+T LAA TS+P+A+ SV  A+               TFD+L+ +
Sbjct: 212 VTGLAATFDIPSFLAGVTILAAATSLPDALVSVRAARSGHGVTSLGNVLGSNTFDLLVAI 271

Query: 366 GLPWLI 371
            +  LI
Sbjct: 272 PIGVLI 277



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 22/67 (32%), Positives = 32/67 (47%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL   ++        +GVG IVGSA+FNIL V    GI     +      + ++   Y 
Sbjct: 62  PELLSVLVTALDGSFGLGVGAIVGSAIFNILVVPGLAGITTTQPLDATRTVVYKEAQFYM 121

Query: 78  ITVSILI 84
           + VS L+
Sbjct: 122 LAVSTLL 128


>UniRef50_UPI000049A3AC Cluster: hypothetical protein 24.t00059;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 24.t00059 - Entamoeba histolytica HM-1:IMSS
          Length = 1424

 Score = 40.7 bits (91), Expect = 0.079
 Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 10/103 (9%)

Query: 130 NMFKDNEEKQDA------ENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKE-- 181
           N  K+N+ KQD+      E+ K  + + HI + +  I+   + N  IKTS   Q  KE  
Sbjct: 224 NKLKENDNKQDSTEEYKIEDEKSQERNLHIKEENETIKSEKEENQQIKTSTPLQTTKEIE 283

Query: 182 -KILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEEN 223
            +     ++ +KV A+ E ++ N+N +++   NE E    E N
Sbjct: 284 PQQSSQEEILEKVIAN-ENENTNINREVEKTQNETESKERESN 325


>UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep:
           Ca2+/Na+ antiporter - Idiomarina loihiensis
          Length = 325

 Score = 40.7 bits (91), Expect = 0.079
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 8/109 (7%)

Query: 285 PLTFIMCIVW--IGSLSYIVA-----WMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSS 337
           PL     I+W  +G L  IV+     W    I  +L + D V+G+T +A GTS+PE  S+
Sbjct: 167 PLPMKPAIMWLIVGLLLLIVSSRALVWGAVNIAVSLGVSDLVIGLTVVAIGTSLPELASA 226

Query: 338 VIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK-ASLTPAEPGHYWV 385
           +   ++               F+ L  +G+   I+  SL P      WV
Sbjct: 227 IAATRKNEHDLALGNVIGSNMFNTLAVVGIAGAIEPVSLEPLVLSRDWV 275



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 10/96 (10%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLA 75
           PEL   +  T   E D+ +G ++GS +FN LAV    GI AG + P+   P  L+RD +A
Sbjct: 221 PELASAIAATRKNEHDLALGNVIGSNMFNTLAVV---GI-AGAIEPVSLEPLVLSRDWVA 276

Query: 76  YGITVSILICI----IHDEYVQWYEAFLLVSLYGVY 107
             +   +L+           +     F+ + LY +Y
Sbjct: 277 MAVLTLLLMVFGIRKARQGRINRVHGFIFICLYLLY 312


>UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45;
           Proteobacteria|Rep: Sodium-calcium exchanger - Vibrio
           fischeri (strain ATCC 700601 / ES114)
          Length = 323

 Score = 40.7 bits (91), Expect = 0.079
 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 8/94 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRD-CL 74
           PEL  +V G    E D+  G I+GS VFNILAV    GI A ++ P +  P  + RD  +
Sbjct: 225 PELAASVAGVLKGEDDMAAGNIIGSNVFNILAV---MGIPA-LINPSEISPDLMGRDFYV 280

Query: 75  AYGITVSILICII-HDEYVQWYEAFLLVSLYGVY 107
             G+++ +LI  +     +   E  +LV+ + VY
Sbjct: 281 MLGVSILLLIMALGKSRSINRIEGGILVTCFCVY 314



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP-LTRDCLAY 76
           PE+ V+       + D  VG ++GS   NI  +A   GI A ++ PL     + R  L  
Sbjct: 55  PEMMVSAAAALDGKTDTAVGNVIGS---NIANIALILGITA-LIKPLAISSAIIRRELPL 110

Query: 77  GITVSILIC-IIHDEYVQWYEAFLLVSLYGVYICIMYY 113
            + V++L   I+ + Y+ +YE  LL+ L+  +I  M Y
Sbjct: 111 MLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFIIAMLY 148



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 20/67 (29%), Positives = 32/67 (47%)

Query: 308 IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           +I     + + V+G+T +A GTS+PE  +SV    +               F+IL  +G+
Sbjct: 201 VIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDDMAAGNIIGSNVFNILAVMGI 260

Query: 368 PWLIKAS 374
           P LI  S
Sbjct: 261 PALINPS 267


>UniRef50_A2F8N8 Cluster: Putative uncharacterized protein; n=2;
            Eukaryota|Rep: Putative uncharacterized protein -
            Trichomonas vaginalis G3
          Length = 1996

 Score = 40.7 bits (91), Expect = 0.079
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 134  DNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKV 193
            + EEK++ E  K  KL  H  + +   E+ H+     K   L ++ +EK  E  +  +K+
Sbjct: 1479 EEEEKKEEEEEKIEKL--HEEEEEEKKEELHEEEEEEKKEELHEE-EEKKEEEEEKIEKL 1535

Query: 194  SASEEGKDKNVNIDMDSKPNEMEIASP---EENLYQPTAEDNTDVEDGSENSLWKWPSNK 250
               EE K +  N +++  P   E+  P   EEN Y+   ED  D E   E+   K     
Sbjct: 1536 HEEEEKKKEQTNEEINYNPAIKEVEGPESEEENKYRKDEEDFED-EKNEESDYKKQKEES 1594

Query: 251  SCLAK 255
              +AK
Sbjct: 1595 ESVAK 1599


>UniRef50_UPI0000498A17 Cluster: sodium/calcium exchanger protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: sodium/calcium
           exchanger protein - Entamoeba histolytica HM-1:IMSS
          Length = 510

 Score = 40.3 bits (90), Expect = 0.10
 Identities = 22/79 (27%), Positives = 41/79 (51%)

Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXX 347
           F++ +++I   +  +  ++  IG  + I  S++G+T L  G SV + VS+VIV+ Q    
Sbjct: 354 FVISVLYIYIFASELVALLQSIGVAMKIDSSILGLTVLCWGNSVGDFVSNVIVSSQGYSE 413

Query: 348 XXXXXXXXXXTFDILLCLG 366
                      F++L+ LG
Sbjct: 414 MGIIASYGGPCFNLLIGLG 432


>UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Chlorobium|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Chlorobium
           ferrooxidans DSM 13031
          Length = 318

 Score = 40.3 bits (90), Expect = 0.10
 Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD-WWPLTRDCLAY 76
           PEL  ++I  +    ++G+GTI+GS +FN L +    G+ A M+ P+      T   L  
Sbjct: 213 PELASSLIAKYRGHDEVGLGTILGSNIFNGLLIV---GVTA-MINPIQVTLRETGTALLI 268

Query: 77  GITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
           GIT  +L   + D  ++  +   L+ LY  Y+   +
Sbjct: 269 GITALLLTFPLSDGRIKKSQGVFLIMLYAGYLIFCF 304


>UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Beggiatoa sp. PS|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Beggiatoa sp. PS
          Length = 253

 Score = 40.3 bits (90), Expect = 0.10
 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 2/96 (2%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL   +IGTF  E ++ VG +VGS +FNIL V     + + + + +    +  D +   
Sbjct: 115 PELATVIIGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPISIDVSQAAIFLD-MPVM 173

Query: 78  ITVSI-LICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
           I V+I  + I  +  ++ +E  L ++ Y  Y   ++
Sbjct: 174 IAVAIACLPIFFNNLIERWEGGLFLAYYIAYTLYLF 209


>UniRef50_A0V1B3 Cluster: Putative uncharacterized protein; n=1;
           Clostridium cellulolyticum H10|Rep: Putative
           uncharacterized protein - Clostridium cellulolyticum H10
          Length = 413

 Score = 40.3 bits (90), Expect = 0.10
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 7/110 (6%)

Query: 137 EKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSAS 196
           +K D   G  + +   ++K+D PIE+      NI     R    E+I ES +  D   A 
Sbjct: 182 QKTDFSIGA-VSIKAEVVKVD-PIERSEAVKNNISMG--RYKLFEEITESDENIDIEKAK 237

Query: 197 EEGKDKNVNIDMDSKPNEMEIASPE-ENLYQPTAEDNTDVEDGSENSLWK 245
            EG  K +  + ++K  E  IAS + +N Y+P  +DN ++ D  +NS  K
Sbjct: 238 TEGLSKIIE-EYETKEQEKTIASVDKDNSYKPV-QDNKEILDKPKNSTTK 285


>UniRef50_UPI0000E494AB Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 575

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 25/100 (25%), Positives = 44/100 (44%)

Query: 137 EKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSAS 196
           E++D E G+D K S    + D   E+  +     K     +D KE   E  +   +    
Sbjct: 338 EEEDKEEGEDKKDSEDEEETDEEGEEDKEEKDEEKKEEEEEDGKEDRKEKDEEKREEVEE 397

Query: 197 EEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVE 236
           +EG++KN     D + +E E+   +E + +   E+  D E
Sbjct: 398 DEGEEKNKEKKEDEEKDEEEMKEKDEKIEEEEKEEEDDEE 437


>UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23;
           Gammaproteobacteria|Rep: Ca2+/Na+ antiporter - Vibrio
           vulnificus
          Length = 321

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 20/39 (51%), Positives = 24/39 (61%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 56
           PEL  ++ G    E D+ VG I+GS VFNILAV    GI
Sbjct: 222 PELAASLAGALKGEDDMAVGNIIGSNVFNILAVMGIPGI 260



 Score = 38.7 bits (86), Expect = 0.32
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 308 IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           II     + D V+G+T +A GTS+PE  +S+  A +               F+IL  +G+
Sbjct: 198 IIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGALKGEDDMAVGNIIGSNVFNILAVMGI 257

Query: 368 PWLIKASLTP--AEPGHYWVKI 387
           P ++  S     A    +WV +
Sbjct: 258 PGILNPSFISEYAMGRDFWVML 279



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 6/96 (6%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW-WPLTRDCLAY 76
           PE+ V+       + D  VG ++GS   NI  +A   GI A +V PL     + R  L  
Sbjct: 52  PEMMVSATAALDGKTDTAVGNVLGS---NIANIALILGITA-LVRPLSINSAVVRRELPL 107

Query: 77  GITVSILI-CIIHDEYVQWYEAFLLVSLYGVYICIM 111
            I V+IL   ++ D ++ +YE  LL  L+ +++  M
Sbjct: 108 MIGVTILAGILLWDSHLGFYEGVLLFVLFTLFLVAM 143


>UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2;
           Bacteria|Rep: Na+/Ca2+-exchanging protein - Salinibacter
           ruber (strain DSM 13855)
          Length = 350

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 20/66 (30%), Positives = 32/66 (48%)

Query: 310 GDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPW 369
           GD    P  + GIT +AAGTSVP+A  S+  ++                FD+L+C+    
Sbjct: 214 GDIFGTPSFLWGITVVAAGTSVPDAFVSIRASRAGNPVTSVANVLGSNIFDLLVCIPAAA 273

Query: 370 LIKASL 375
           L+  ++
Sbjct: 274 LVAGTV 279



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)

Query: 18 PELFVNVIGTFIT-EGDIGVGTIVGSAVFNILAVAACCGIGA 58
          PEL   V+   +  + ++GV  +VGSA+FNIL + A  G+ A
Sbjct: 58 PELSTAVLSAALHGDFELGVAAVVGSALFNILMIPALAGLWA 99


>UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1;
           Moritella sp. PE36|Rep: Putative uncharacterized protein
           - Moritella sp. PE36
          Length = 340

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 1/82 (1%)

Query: 299 SYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXT 358
           S I+ W    +   + + D ++G+T +A GTS+PE  +++   ++              T
Sbjct: 183 SQIMVWGSVQLAKAMGVSDLLIGLTIVAFGTSLPELAAAIAGVRRGMPEIAFATVIGSNT 242

Query: 359 FDILLCLGLPWLIKASL-TPAE 379
           F++L  L  P LI   L  PAE
Sbjct: 243 FNLLGVLAFPGLIGDGLQLPAE 264



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL V+ I +F     + VG  +GS + N   V A C +   +V+ + +       L + 
Sbjct: 54  PELVVSAIASFNGAEGLAVGNAIGSNIINCGLVLALCALFMPLVIKVRFIKRELPILVFA 113

Query: 78  ITVSILICIIHDEYVQWYE--AFLLVSLYGVYI 108
           +  +I + + +     W      LL++LY VY+
Sbjct: 114 LIATIAL-MSNGSITMWDSLILILLLALYCVYL 145



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCLAY 76
           PEL   + G      +I   T++GS  FN+L V A  G IG G+ +P +   LTRD    
Sbjct: 216 PELAAAIAGVRRGMPEIAFATVIGSNTFNLLGVLAFPGLIGDGLQLPAE--VLTRDLPML 273

Query: 77  GITVSILI 84
            I  + ++
Sbjct: 274 SIMTAFMV 281


>UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
           Rhodobacter sphaeroides|Rep: Na+/Ca+ antiporter, CaCA
           family - Rhodobacter sphaeroides (strain ATCC 17029 /
           ATH 2.4.9)
          Length = 305

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 27/98 (27%), Positives = 52/98 (53%), Gaps = 8/98 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLA 75
           PEL  + I  +    +I VG ++GS +FN+L +    GI  G+V+P+        R+ + 
Sbjct: 211 PELATSAIAAWRKHSEIAVGNVIGSNIFNVLGI---LGI-TGLVLPIQGLDPRFLREDMP 266

Query: 76  YGITVSILICIIHD--EYVQWYEAFLLVSLYGVYICIM 111
           + +  S+L+ ++    + V  +   LL++ YG Y+ +M
Sbjct: 267 WVLGCSLLLVLMAFALKGVPRWAGALLLAAYGGYVALM 304



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 20/65 (30%), Positives = 33/65 (50%)

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           T I  +  I ++V+G+T +A GTS+PE  +S I A +               F++L  LG
Sbjct: 186 TQIARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVGNVIGSNIFNVLGILG 245

Query: 367 LPWLI 371
           +  L+
Sbjct: 246 ITGLV 250


>UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Marinobacter sp. ELB17|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Marinobacter sp. ELB17
          Length = 328

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 288 FIMCIVWIGSL---SYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQX 344
           F+M  + I +L   S ++       G  L +P++V+G+T +A GTS+PE  +SV  A++ 
Sbjct: 175 FVMVTIGIATLVIGSEVLVQGAVAGGFALGVPEAVIGMTVIAFGTSLPELTASVAAARKG 234

Query: 345 XXXXXXXXXXXXXTFDILLCLGLPWLIK 372
                         F+IL  + +  ++K
Sbjct: 235 QSDMIIGGIVGSNIFNILSVMAITAVVK 262


>UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 433

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 18/58 (31%), Positives = 35/58 (60%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           L FI+ +VWI   +  +  ++   G  L + ++++G+TFLA G S+ + V+   +A+Q
Sbjct: 355 LAFIVSVVWIYVTANEIVNILQSFGIVLGLSNAILGLTFLAWGNSIGDLVADTTMARQ 412



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSV 338
           + F+  ++ I +  Y     +T+I  TL +  +V G+TFLA G   P+  S++
Sbjct: 42  MLFLFIVLGITADDYFCP-SLTVISKTLRLSQNVAGVTFLAYGNGAPDIFSAI 93


>UniRef50_Q9HS69 Cluster: Cation antiporter; n=2;
           Halobacteriaceae|Rep: Cation antiporter - Halobacterium
           salinarium (Halobacterium halobium)
          Length = 318

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 13/97 (13%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAY- 76
           PEL  +V+     E D  +G +VGS ++N+LAV    GI A ++VP+    +T+  LA+ 
Sbjct: 224 PELATSVVSALRDEADFSIGNVVGSNIYNVLAV---IGIVA-ILVPI---TVTKGTLAFE 276

Query: 77  -----GITVSILICIIHDEYVQWYEAFLLVSLYGVYI 108
                G TV  L  +   + +   E  +L+  YG ++
Sbjct: 277 LPVMLGFTVLALGMMAVGDRITRVEGAVLIGSYGGFV 313


>UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25;
           Enterobacteriaceae|Rep: Inner membrane protein yrbG -
           Escherichia coli (strain K12)
          Length = 325

 Score = 39.9 bits (89), Expect = 0.14
 Identities = 19/65 (29%), Positives = 34/65 (52%)

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           T++ +   I +  MG+T +A GTS+PE  +++   ++               F+I++ LG
Sbjct: 198 TVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLG 257

Query: 367 LPWLI 371
           LP LI
Sbjct: 258 LPALI 262



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 19/66 (28%), Positives = 33/66 (50%)

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           +I+  T  IP  ++G+T ++ GTS+PE + S+  +                  +ILL LG
Sbjct: 27  SILCRTFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVGTALGSNIINILLILG 86

Query: 367 LPWLIK 372
           L  L++
Sbjct: 87  LAALVR 92



 Score = 34.7 bits (76), Expect = 5.2
 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 8/104 (7%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCLAY 76
           PEL   + G    E DI VG I+G+ +FNI+ V      I  G + PL +   +RD  + 
Sbjct: 223 PELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAY---SRD-YSV 278

Query: 77  GITVSI---LICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 117
            + VSI   L+C             LL   + V++ ++Y+  PI
Sbjct: 279 MLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPI 322


>UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=9; Bacteroidetes|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Flavobacteria
           bacterium BBFL7
          Length = 317

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 293 VWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXX 352
           +W GS   +V   + I   +L IP+S++ ++ +A GTSVPE  +S+I A +         
Sbjct: 178 LWQGS-ELLVKGAVDIAA-SLGIPESIIAVSMVALGTSVPELAASIIAALKKEKAISLGN 235

Query: 353 XXXXXTFDILLCLGLPWLIK 372
                 F+I   LG+  LI+
Sbjct: 236 LIGSNIFNIGSVLGITALIQ 255


>UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamma
           proteobacterium HTCC2207|Rep: Putative Ca2+/Na+
           antiporter - gamma proteobacterium HTCC2207
          Length = 330

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 20/80 (25%), Positives = 40/80 (50%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           L FI+ +  + + + +  W    I  +L I + ++G+T +A GTS+PE  +SV+ A +  
Sbjct: 175 LWFIVGLAVLLASAEVTVWSAKTIAQSLGISELIIGLTVVAIGTSLPELAASVVSAMRGH 234

Query: 346 XXXXXXXXXXXXTFDILLCL 365
                        F+++L +
Sbjct: 235 HDIAIGNVFGSNLFNLMLVM 254



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PLDWWPLTRDCLAY 76
           PEL  +V+       DI +G + GS +FN++ V    GI + M + P+      RD  + 
Sbjct: 221 PELAASVVSAMRGHHDIAIGNVFGSNLFNLMLVMPAAGIISPMTISPM---VFNRDFASL 277

Query: 77  GITVSILICII 87
            I   +LI ++
Sbjct: 278 AIMTLLLIAMV 288


>UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Silicibacter sp. TM1040|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Silicibacter sp. (strain TM1040)
          Length = 327

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +VI     +GD+  G +VGS ++NIL +     + A   +P D        +   
Sbjct: 232 PELVTSVIAALKRQGDVAFGNVVGSNIYNILGIGGTTALIAPSDLPGDILRFDAPVMIL- 290

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
           ++   ++       V   E  +L++ YG+YI +++
Sbjct: 291 VSAGFVLFAATGFRVGRREGAILLAGYGLYIWMIW 325



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 22/65 (33%), Positives = 33/65 (50%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
           I ++V+G+T +A GTS+PE V+SVI A +               ++IL   G   LI  S
Sbjct: 215 ISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFGNVVGSNIYNILGIGGTTALIAPS 274

Query: 375 LTPAE 379
             P +
Sbjct: 275 DLPGD 279


>UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; Marinomonas|Rep: Na+/Ca+ antiporter, CaCA family
           precursor - Marinomonas sp. MWYL1
          Length = 332

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 1/90 (1%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           +  I   V IGS S ++ W    I   L + + V+G+T +A GTS+PE  +SV   ++  
Sbjct: 184 IALIGLAVLIGS-SKLLVWGAIGIATALGVSELVIGLTIVAVGTSLPELAASVSSVRKGH 242

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLIKASL 375
                        F++   L LP L+   L
Sbjct: 243 HDIAIGNILGSNIFNLATVLPLPALLAPGL 272



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 8/100 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAY 76
           PEL  +V        DI +G I+GS +FN+  V     + A  +V  D   ++RD     
Sbjct: 229 PELAASVSSVRKGHHDIAIGNILGSNIFNLATVLPLPALLAPGLV--DQSVISRDFPWVL 286

Query: 77  GITVSILICII-----HDEYVQWYEAFLLVSLYGVYICIM 111
           G+TV++ + I       +  +  +    L++ YGVY+ I+
Sbjct: 287 GLTVALALAIFIFKKTKNNSIPRWVGLPLIASYGVYLFII 326


>UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; sulfur-oxidizing symbionts|Rep: Na+/Ca+ antiporter,
           CaCA family precursor - Ruthia magnifica subsp.
           Calyptogena magnifica
          Length = 317

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 25/96 (26%), Positives = 54/96 (56%), Gaps = 8/96 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL V++      +  + +G ++GS +FN +AV A  G+     VP++   ++RD     
Sbjct: 221 PELAVSITSVLKKQYAMVIGNVIGSNLFNTIAVLAIPGLIHPSDVPVE--VISRD-YPVM 277

Query: 78  ITVSILICIIHDEY-----VQWYEAFLLVSLYGVYI 108
           + ++IL+ I+  ++     +  ++ F+L+ ++G+YI
Sbjct: 278 LLLTILLFIVSYKFNKKHIINRFKGFVLIGMFGLYI 313



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 287 TFIMCIVWIGSL---SYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           T+IM IV + SL   + +V W    +     + D ++G++ +A GT +PE   S+    +
Sbjct: 173 TWIMLIVNLVSLISSAKLVVWGSIEVAKVFGVSDLIIGLSVVALGTGLPELAVSITSVLK 232

Query: 344 XXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
                          F+ +  L +P LI  S  P E
Sbjct: 233 KQYAMVIGNVIGSNLFNTIAVLAIPGLIHPSDVPVE 268


>UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr8 scaffold_150, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 593

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 19  ELFVNVIG-TFITEGDIGVGTIVGSAVFNILAVAACCGIGAG-MVVPLDWWPLTRDCLAY 76
           ++F +++  T  ++GD+G+  ++G A F    V     I  G   + +D     RD + +
Sbjct: 164 DVFASIVSFTRTSDGDVGLNIVLGGAFFVSSVVVGIISIFIGPRQISVDKPSFIRDVIFF 223

Query: 77  GITVSILICIIHDEYVQWYEAFLLVSLYGVYIC 109
            I ++ L+ II    V ++ +   VS+Y  Y+C
Sbjct: 224 LIALASLLVIIIIGKVSFWGSVCFVSIYFFYVC 256



 Score = 39.5 bits (88), Expect = 0.18
 Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 8/157 (5%)

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           W    F+M + W   ++  +  ++   G+ L I  +V+G+T LA G S+ + +++V +A 
Sbjct: 430 WLAGGFLMSVTWTYIIAEELVSLLVSFGNILGISPAVLGLTVLAWGNSLGDLIANVALAA 489

Query: 343 ---QXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXX 399
              Q               F+ L+ LGL  +  A      P  Y + I+     Y  +  
Sbjct: 490 NGGQDGVQIAVSGCYAGAMFNTLVGLGLSMVFSA--WHEYPAPYIIPIDPS--LYETVGF 545

Query: 400 XXXXXXXXXXFWFNK-FKLDAAVGRACLAMYAMFLIL 435
                        NK  K D  +G   LA+Y  FL L
Sbjct: 546 LMSGLLWALVILPNKNMKPDRFLGIGLLAIYVCFLFL 582


>UniRef50_Q59NL4 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 402

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 24/128 (18%), Positives = 56/128 (43%), Gaps = 3/128 (2%)

Query: 133 KDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDK 192
           ++ E+K++    ++ +    ++ +D+ +E+   +N N       +     I+   D  D+
Sbjct: 267 EEKEKKEEDNKEEEEEEEEEVVSMDIDMEENENNNNNTDKEKKEESNTNSIIFHNDEDDQ 326

Query: 193 VSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSC 252
               E   D    + +DS  +  E+  PEE   +    +NT + D  E   +   +N+  
Sbjct: 327 HDDHEINSDA---MSIDSIDSNDELEEPEEEEEEEEETNNTYINDYEEMEGYGGDNNRRY 383

Query: 253 LAKITKIV 260
             ++T+I+
Sbjct: 384 KVQVTEII 391


>UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Methanoculleus marisnigri JR1|Rep: Na+/Ca+ antiporter,
           CaCA family - Methanoculleus marisnigri (strain ATCC
           35101 / DSM 1498 / JR1)
          Length = 311

 Score = 39.5 bits (88), Expect = 0.18
 Identities = 18/63 (28%), Positives = 33/63 (52%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           + +   IP  V+G++ +A GTS+PE  +S++ A +               F++LL LG+ 
Sbjct: 192 LAEAFGIPAFVIGVSVVAVGTSLPELATSIVAAARDEGSISIGNILGSNIFNLLLVLGIS 251

Query: 369 WLI 371
            L+
Sbjct: 252 LLL 254



 Score = 38.7 bits (86), Expect = 0.32
 Identities = 30/101 (29%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +++     EG I +G I+GS +FN+L V    GI   ++ P+    L    +   
Sbjct: 215 PELATSIVAAARDEGSISIGNILGSNIFNLLLV---LGISL-LLAPVTVGSLVDIAVVVL 270

Query: 78  ITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 117
            +V+IL +       V+ + A LL+  Y  YI   +   PI
Sbjct: 271 FSVAILPLLFARPSVVRGWSALLLLG-YAAYIAWSFGAVPI 310


>UniRef50_UPI00006CB3BD Cluster: hypothetical protein
           TTHERM_00473160; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00473160 - Tetrahymena
           thermophila SB210
          Length = 1411

 Score = 39.1 bits (87), Expect = 0.24
 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 5/114 (4%)

Query: 119 NFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQD 178
           NFAK +       FK   E+QD+ N  D    T    ++  ++ + Q  G+ + +    D
Sbjct: 380 NFAKKNQSQKDETFKSGMEEQDSNNTYDNSTKT---PVNTDLKSQIQTKGSEQFALKNSD 436

Query: 179 AKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDN 232
           +  K+ ++V+   K     +    N NI +  K   +E+ S +  L  P    N
Sbjct: 437 SNSKLKKNVNNQSKTLQENQKSKINKNIPITKK--SLELTSSQNKLTSPNTNQN 488


>UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=4; Proteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Desulfovibrio desulfuricans (strain G20)
          Length = 322

 Score = 39.1 bits (87), Expect = 0.24
 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 283 WFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           W  +  ++ +V     S I+ W    I     + D ++G+T +A GTS+PE  SS+I  +
Sbjct: 176 WLSVGLVLLVV----SSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATR 231

Query: 343 QXXXXXXXXXXXXXXTFDILLCLGL 367
           +               F+ L  +G+
Sbjct: 232 KGEHDIALGNVLGSNLFNTLAVVGI 256



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 27/70 (38%), Positives = 40/70 (57%), Gaps = 7/70 (10%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLA 75
           PEL  ++I T   E DI +G ++GS +FN LAV    GI AG + P+   P    RD + 
Sbjct: 221 PELASSIIATRKGEHDIALGNVLGSNLFNTLAVV---GI-AGAIHPMAIGPEVFNRDMMV 276

Query: 76  Y-GITVSILI 84
             G+T+S+ +
Sbjct: 277 MAGLTLSLFV 286


>UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Roseobacter sp. CCS2|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Roseobacter sp. CCS2
          Length = 326

 Score = 39.1 bits (87), Expect = 0.24
 Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 310 GDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPW 369
           G  + +P++V+G+T +A GTS+PE  + +  A++              TF+IL  + L  
Sbjct: 204 GSAIGVPEAVIGMTVVAFGTSLPELSTCIAAARKQSVGLILGNIIGSNTFNILSIIALTA 263

Query: 370 LIK-ASLTPAEPG-HYWVKINSMGLEYSA 396
            IK   + P   G   WV + ++ + +SA
Sbjct: 264 AIKPLDVDPVLLGMELWVTV-AVAVVFSA 291


>UniRef50_A2FHT1 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 766

 Score = 39.1 bits (87), Expect = 0.24
 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 4/110 (3%)

Query: 130 NMFKDNEEKQDAENGKDLKLSTHIL-KIDVPIEQRHQHNGNI-KTSPLRQDAKEKILESV 187
           N F  +  K+ +EN  D+K+S  I  K+D   E+      N+ KT  L    K+  +  +
Sbjct: 619 NDFVIDINKKPSEN--DMKISDEIKEKVDDLDEEEEDEESNLSKTLKLPLQTKKDEINKL 676

Query: 188 DVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVED 237
           D  ++    EE  +     D D K N+ +  + EE+  +   ED  D E+
Sbjct: 677 DEKEEEEQEEEKDENKEEEDNDEKDNDNDEENEEEDKDEKEEEDKDDDEE 726


>UniRef50_A2DZZ4 Cluster: Putative uncharacterized protein; n=1;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 1155

 Score = 39.1 bits (87), Expect = 0.24
 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 4/113 (3%)

Query: 136  EEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSA 195
            + K + E+  + +   + ++I   +E+  + +G      L +   EK  E  + SD+   
Sbjct: 912  QRKAELEDNSEEEEKENQIQIQ-KVEEEEEDDGEDFIKSLERKVAEKKAELEENSDEEDE 970

Query: 196  SEEGKDKNVNIDMDSKPNEME-IASPEENLYQPTAE--DNTDVEDGSENSLWK 245
             E+ K++ VN + +   +E + I S E+ + Q  AE  +N++ ED  EN L K
Sbjct: 971  EEKEKEQEVNEENEDDDDENDFIKSLEKRVAQKRAELEENSEEEDDDENDLIK 1023


>UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1;
            Ustilago maydis|Rep: Putative uncharacterized protein -
            Ustilago maydis (Smut fungus)
          Length = 1117

 Score = 39.1 bits (87), Expect = 0.24
 Identities = 31/160 (19%), Positives = 66/160 (41%), Gaps = 7/160 (4%)

Query: 288  FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXX 347
            F + ++WI ++   V  ++  +G  + + D+++G+T  A G S+ + V+++ +AK     
Sbjct: 950  FTVSVMWIMTIVDEVVSILQTVGIIVGLSDAILGLTVFAVGNSLGDLVANITIAKLGHPV 1009

Query: 348  XXXXXXXXXXTFDILLCLGL--PWLIKASLT----PAEPGHYWVKINSMGLEYSAIXXXX 401
                        ++LL +G+   WL+               Y +  N   L  S +    
Sbjct: 1010 MAISACFAGPMLNLLLGIGISGTWLLSDGNAHWDHTGAADIYPIDFNPT-LLVSGLGLLL 1068

Query: 402  XXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIEL 441
                       N F+L   +G + +A Y + + +  L E+
Sbjct: 1069 ILIGTLIAVPMNNFELTRPIGISLIAAYMLIMTVNLLTEI 1108


>UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane
           protein; n=3; Pyrococcus|Rep: Na+/Ca2+ exchange integral
           membrane protein - Pyrococcus abyssi
          Length = 314

 Score = 39.1 bits (87), Expect = 0.24
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 7/97 (7%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPL--DWWPLTRDCLA 75
           PE  V+ I ++     I +G  VGSA+ NI   A   GI A M+ PL  D        + 
Sbjct: 54  PEATVSAISSYKGNSGIALGNAVGSALANI---ALILGISA-MITPLKVDEVANENSLIM 109

Query: 76  YGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
            G+T+   + +I+ E +   E   LV +YG ++  +Y
Sbjct: 110 LGVTLYAWLLMINGE-ISRIEGLTLVLIYGAFLYYLY 145



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 17/58 (29%), Positives = 31/58 (53%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           IP+ V+G+T ++ GTS+PE  +S+  A +                DIL+ +G+  +I+
Sbjct: 196 IPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADIIDILMVIGIASIIR 253


>UniRef50_UPI00006CB708 Cluster: hypothetical protein
           TTHERM_00494560; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00494560 - Tetrahymena
           thermophila SB210
          Length = 666

 Score = 38.7 bits (86), Expect = 0.32
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 14/116 (12%)

Query: 135 NEEKQDAENGKDLKLSTHILKIDVPIEQRHQ------HNGNIKTSPLRQDAKEKILESVD 188
           NE     E+ ++   S +I   ++P ++R Q      H+G +K  PL Q+ K  ++   D
Sbjct: 180 NENNISTEHNEN---SRYIRSNNLPSQERDQNNSPGAHSGELKLPPL-QEQKNILVSEND 235

Query: 189 VSDKVSASE---EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSEN 241
           +S +  +S+   +G  KN +I      N + + S   N Y    + NT++ +GS N
Sbjct: 236 ISQRSQSSKLVSKGTHKN-SITHGINSNNISLNSGSGNKYNYQVKGNTEINNGSHN 290


>UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Pseudomonas syringae group|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Pseudomonas syringae pv. phaseolicola (strain 1448A /
           Race 6)
          Length = 343

 Score = 38.7 bits (86), Expect = 0.32
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 3/92 (3%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           P L  ++I  F  E DI VG ++GS +FN+L V     + A + + +    +  D L   
Sbjct: 208 PALMTSLIAAFRGERDIAVGNVIGSNLFNLLGVLGVTALFAPVPLTVSPNAMVFD-LPIM 266

Query: 78  ITVSIL-ICIIHDEY-VQWYEAFLLVSLYGVY 107
           + VS+L + + +  Y +   E   L+SLY  Y
Sbjct: 267 LGVSLLCVPLFYSGYRIDRMEGVFLLSLYLTY 298



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 7/70 (10%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           P++ V++   F    DI VG+++G  +FN+L +   C     +++PL    + R  L   
Sbjct: 45  PQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGLC----ALIIPL---RVARQVLHID 97

Query: 78  ITVSILICII 87
           I + I  C++
Sbjct: 98  IPLMIGACLL 107


>UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like
           protein; n=1; Salinibacter ruber DSM 13855|Rep:
           K+-dependent Na+/Ca+ exchanger-like protein -
           Salinibacter ruber (strain DSM 13855)
          Length = 317

 Score = 38.7 bits (86), Expect = 0.32
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDC-L 74
           PE  VNV      E  + +G I+GS + N+  +   C +    V+PL   P  L R+  +
Sbjct: 52  PEYLVNVFALISGESPLAIGNIIGSNISNVALILGACAV----VLPLAVTPEVLRREYPV 107

Query: 75  AYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 114
             G+ V   +C + D  +   +  L+V L       ++YD
Sbjct: 108 MLGVMVLFYLCAL-DGVIGARDGVLMVVLLSGLAAYVFYD 146



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 16/45 (35%), Positives = 25/45 (55%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 62
           PEL  +++GT   E D+ VG ++GS + N+L V     I   + V
Sbjct: 223 PELAASMVGTLKQEVDMTVGNVIGSNLLNVLFVVGTLAIAEPITV 267


>UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: Na+/Ca+
           antiporter, CaCA family precursor - Alkalilimnicola
           ehrlichei (strain MLHE-1)
          Length = 327

 Score = 38.7 bits (86), Expect = 0.32
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 10/106 (9%)

Query: 278 PRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSS 337
           PR   W  L  ++ ++     +    W  T + +   + ++V+G+T +A GTS+PE  + 
Sbjct: 175 PRALLWLLLGLVVLLI----SAQTAVWAATGLAERAGVAETVVGLTLVAVGTSLPELATC 230

Query: 338 VIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPA--EPG 381
           +  A++               F++L  LGL     A+L P   EPG
Sbjct: 231 LAAARRSQGDIAIGNIIGSNIFNLLGVLGL----AATLRPVALEPG 272


>UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein -
           Eubacterium ventriosum ATCC 27560
          Length = 339

 Score = 38.7 bits (86), Expect = 0.32
 Identities = 19/67 (28%), Positives = 31/67 (46%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           +   L +P  V+G+T +A GTS+PE   S   A +               F++L+ +G+ 
Sbjct: 31  VAKRLRVPSIVIGLTIVAVGTSLPELAVSTFAAVKHSNAIALGNVVGSNIFNLLMVIGIT 90

Query: 369 WLIKASL 375
            L K  L
Sbjct: 91  ALFKDML 97



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 17/51 (33%), Positives = 28/51 (54%)

Query: 317 DSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           ++++G+T +A GTS+PE V+S + A +                +ILL LGL
Sbjct: 226 ETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIGNVVGSNISNILLVLGL 276


>UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;
           Loktanella vestfoldensis SKA53|Rep: Putative
           sodium/calcium exchanger - Loktanella vestfoldensis
           SKA53
          Length = 305

 Score = 38.7 bits (86), Expect = 0.32
 Identities = 28/71 (39%), Positives = 39/71 (54%), Gaps = 5/71 (7%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV-VPLDWWPLTRDC-LA 75
           PEL   V+     E DI +G IVGS +FNILA+    GI A +  +P+D   L  D  + 
Sbjct: 210 PELATTVMAAIRGERDIALGNIVGSNIFNILAI---LGITAVVTPIPVDARFLNVDTPVV 266

Query: 76  YGITVSILICI 86
            GIT+ +L  +
Sbjct: 267 IGITLLLLALV 277


>UniRef50_UPI00006CE59A Cluster: probable Mg2+-specific channel-like
           exchanger, putative; n=1; Tetrahymena thermophila
           SB210|Rep: probable Mg2+-specific channel-like
           exchanger, putative - Tetrahymena thermophila SB210
          Length = 625

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 64  LDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQN--FA 121
           +D W L RD + Y + +S+ I  + +  V W+   +++  Y  +I +  Y++ I+   F 
Sbjct: 147 IDGWQLLRDSIWYCVGLSLFIIFLFENLVTWWAGLVMICYYFSHIILQSYNETIREEMFL 206

Query: 122 KGSWKWVSNMFKDNEE 137
               K   ++F  +E+
Sbjct: 207 LVGLKHEDDLFNADEQ 222


>UniRef50_UPI000023F701 Cluster: hypothetical protein FG10084.1; n=1;
            Gibberella zeae PH-1|Rep: hypothetical protein FG10084.1
            - Gibberella zeae PH-1
          Length = 4221

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 134  DNEEKQ--DAENGKDLKLSTHILKIDVPIEQRHQHNGNI--KTSPLRQDAKEKILESVDV 189
            + E KQ  D   G D K  T    +D P       +      T P +Q A++  +   D 
Sbjct: 1946 EEEAKQPIDDATGHDEKPETESPPLDKPANDEPALDDKDLGATRPAQQTAEDVEMCDEDS 2005

Query: 190  SDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENS 242
            +D+  A +E K +     + SKP E+E  + EE     T  D+ D++D +E S
Sbjct: 2006 ADEAPAVDE-KQETPGDPVPSKPEEVEDTTLEEKPVVETLADDKDIQDAAEAS 2057


>UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Halothermothrix orenii H 168|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Halothermothrix orenii H 168
          Length = 383

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV--AACCGIGAGMVVPLDWWPLTRDCLA 75
           PEL   +       G++ VG IVG+ + N+L V  +A      G+ VP +++ L    + 
Sbjct: 284 PELMTAITAVRKGHGELAVGNIVGADILNVLFVVGSAASVTAGGLNVPANFYRLQIPTMV 343

Query: 76  YGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 112
             +    L     +E +   E  +L  LY +Y+ + Y
Sbjct: 344 IILVTFRLFSRGRNEEITKKEGIVLFLLYVIYLILNY 380


>UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus obeum ATCC 29174
          Length = 336

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 6/84 (7%)

Query: 289 IMCIVWIGSLSYIVAWMITI-----IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
           I+CIV  G+++      +T+     I   L +  +++G+T ++ GTS+PE V+SV+ A++
Sbjct: 195 ILCIVG-GAVAIAFGGDMTVDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSVVAARK 253

Query: 344 XXXXXXXXXXXXXXTFDILLCLGL 367
                          F+IL+ LG+
Sbjct: 254 NEVDMAVGNAVGSNIFNILMVLGI 277



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 15/48 (31%), Positives = 26/48 (54%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 65
           PE  V+V  + +   ++ V  +VGS +FN++ V   C I   ++V  D
Sbjct: 61  PETAVSVTASLVHNNELAVSNVVGSNIFNLMFVIGVCAIMTPIMVQKD 108



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +V+     E D+ VG  VGS +FNIL V       + M +  +   +    +  G
Sbjct: 242 PELVTSVVAARKNEVDMAVGNAVGSNIFNILMVLGIASAISPMSLISE--NVIDILVLVG 299

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVY 107
            +V +      D  +   E   +V++Y +Y
Sbjct: 300 FSVVVWFFARSDRKITRNEGIAMVAMYLIY 329


>UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 305

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 4/95 (4%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PE  V++        DI V  I+GS +FN L V   C   +G     D   L RD +   
Sbjct: 50  PEASVSINAALAGNNDIAVSNIIGSNIFNGLIVVGICAFISGFKTNKD--ILKRD-MPVN 106

Query: 78  ITVSILICI-IHDEYVQWYEAFLLVSLYGVYICIM 111
           I +++++CI I +  +   E  LL++    YI  M
Sbjct: 107 ILITVILCIMIANGKLSRIEGILLLAGMIFYILNM 141



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 15/53 (28%), Positives = 28/53 (52%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           +  + +G+T +A GTS+PE V+S++  ++               F+IL  LG+
Sbjct: 194 VSQNFIGLTIVAIGTSLPELVTSIVATRKGDSGLALGNAIGSNIFNILFILGM 246


>UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2;
           Bacteroidetes|Rep: Putative uncharacterized protein -
           Algoriphagus sp. PR1
          Length = 318

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 17/64 (26%), Positives = 34/64 (53%)

Query: 308 IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           ++  +  + + ++G+T +AAGTS+PE  +SV+ + +               F+I L LG+
Sbjct: 196 VMAQSFGVSEKIIGLTIVAAGTSLPELATSVVASLKKNNDIAIGNIIGSNIFNIFLILGV 255

Query: 368 PWLI 371
             +I
Sbjct: 256 SSII 259



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW-WPLTRDC-LA 75
           PEL  +V+ +     DI +G I+GS +FNI  +    G+ + ++ PLD+     +D  + 
Sbjct: 220 PELATSVVASLKKNNDIAIGNIIGSNIFNIFLI---LGV-SSIINPLDYQLSFNKDLYIL 275

Query: 76  YGITVSILICII--HDEYVQWYEAFLLVSLYGVYICIM 111
            G T+ + + +     + +  +EA +L+  Y VYI  +
Sbjct: 276 LGGTIFLFLAMFTGKRKSLDRWEAGILLLTYLVYIAYL 313



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 292 IVWIGSLSYIVA---WMI---TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           I+ IG L  +V    W++   +++  T  + D  +G+T +A GTS PE V + I +    
Sbjct: 6   ILLIGGLLLLVKGADWLVDGASVLAKTHKVSDLAIGLTIVAFGTSAPELVVNSIASSDHL 65

Query: 346 XXXXXXXXXXXXTFDILLCLGLPWLI 371
                        F++ + LG+  LI
Sbjct: 66  PDLVFGNVIGSNNFNLFIILGIAGLI 91


>UniRef50_A4RX12 Cluster: CaCA family transporter: sodium
           ion/potassium ion/calcium ion; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: CaCA family transporter: sodium
           ion/potassium ion/calcium ion - Ostreococcus lucimarinus
           CCE9901
          Length = 569

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 35/168 (20%), Positives = 63/168 (37%), Gaps = 4/168 (2%)

Query: 278 PRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSS 337
           P F + F   F+  I W+  +S  +   +  +     I + V G++F+A G  + + V+ 
Sbjct: 400 PEFASMF--AFVQSICWMHLMSNELVMSLGALAKIFGIDEEVFGVSFVAWGDGIGDLVAC 457

Query: 338 VIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAI 397
             VAK                F++L  +GL   I    T      + VK   + L   ++
Sbjct: 458 HAVAKAGQVTMAVVACFAGPVFNLL--IGLASSIAFLTTILGDLPFNVKQGEIVLAVGSL 515

Query: 398 XXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFF 445
                           +F++  +   A  A Y  FL++  L E  + F
Sbjct: 516 FSVMFTISQLRHRSPREFEIPRSFANAAFATYGAFLLIYLLCEARLLF 563


>UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces
           cerevisiae YDL206w; n=1; Kluyveromyces lactis|Rep:
           Similar to sgd|S0002365 Saccharomyces cerevisiae YDL206w
           - Kluyveromyces lactis (Yeast) (Candida sphaerica)
          Length = 684

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 20/90 (22%), Positives = 41/90 (45%), Gaps = 2/90 (2%)

Query: 285 PLTFIMCIVWIGSLS--YIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           PL+ + C + +G ++  Y+   +  I  + L I D + G+T LA G ++P+  S+    K
Sbjct: 37  PLSLLTCFIALGIITSDYLTPNLTVISQELLFISDRISGMTLLALGNAIPDITSTYKAMK 96

Query: 343 QXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           +               F + + +G   L++
Sbjct: 97  RGTTTLAIGESLGAIFFLLTVVIGSMLLVR 126


>UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 682

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 19/76 (25%), Positives = 35/76 (46%)

Query: 267 VFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLA 326
           +F  TIP C+           F+  I WI   +  +  +   I  +  + D ++G+T  A
Sbjct: 506 LFSLTIPSCKHYIIMTGSLFGFVSSICWIALFATEIISIFQAIATSYNLSDDILGLTVFA 565

Query: 327 AGTSVPEAVSSVIVAK 342
            G SV + +S+  +A+
Sbjct: 566 WGNSVGDLISNFTIAR 581


>UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1;
           Haloarcula marismortui|Rep: Na+/Ca2+-exchanging protein
           - Haloarcula marismortui (Halobacterium marismortui)
          Length = 335

 Score = 38.3 bits (85), Expect = 0.42
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 281 KNWFPLTFIMCIVWIGSLSYIV-AWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
           + W  L   + I+ +G    +  A  + +I DT   P  + G+T +AAGTS+P+A  SV 
Sbjct: 179 REWGMLGVGLVIITVGVEGMVQGALSLGVIFDT---PTFLWGLTVIAAGTSLPDAFVSVR 235

Query: 340 VAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLT 376
            AK               TF++L+ + +  L+    T
Sbjct: 236 AAKDDDSVTSLTNVLGSNTFNLLVAIPVGVLLAGRAT 272



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 19/42 (45%), Positives = 26/42 (61%), Gaps = 1/42 (2%)

Query: 18 PELFVNVIGTFI-TEGDIGVGTIVGSAVFNILAVAACCGIGA 58
          PE+   VI T I  E  +GVG IVGSA+FN+L + A   + +
Sbjct: 55 PEISSVVISTVIHDEFSLGVGAIVGSAIFNLLVIPALAALSS 96


>UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca
           exchanger; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Na/Ca exchanger -
           Strongylocentrotus purpuratus
          Length = 367

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 3/43 (6%)

Query: 18  PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACCGIG 57
           PE+ ++VI   G     G +G  TIVGSA FN+L + A C +G
Sbjct: 105 PEILLSVIEIAGNGFQSGPLGPSTIVGSAAFNLLIITAVCIMG 147


>UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=8; Bacteroidales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 317

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 285 PLTFIMCIVWIGSLSY---IVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVA 341
           PL+ IM I  + +L +   +      ++   + + +SV+ IT +A GTS+PE V++++ A
Sbjct: 170 PLSIIMVIGGLVALVFGGDLFVDNAAMLAGRMGVSESVVAITIVAGGTSLPELVTTLVAA 229

Query: 342 KQXXXXXXXXXXXXXXTFDILLCLGL 367
            +               F+ILL LG+
Sbjct: 230 IKKRPGMAIGNIVGSNLFNILLILGV 255



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 4/47 (8%)

Query: 18 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPL 64
          PEL V+++       DI +G ++GS +FNILA+    GI A +++PL
Sbjct: 52 PELTVSLMAALKGSADIAIGNVIGSNIFNILAIV---GITA-LIMPL 94



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 20/63 (31%), Positives = 29/63 (46%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           I     + D V+G+T LA GTS PE   S++ A +               F+IL  +G+ 
Sbjct: 29  IAKRFRLSDLVIGLTVLAFGTSAPELTVSLMAALKGSADIAIGNVIGSNIFNILAIVGIT 88

Query: 369 WLI 371
            LI
Sbjct: 89  ALI 91


>UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=9; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Silicibacter
           pomeroyi
          Length = 309

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRD-CLAY 76
           PEL  +VI  +  + +I VG IVGS +FN+L +     + A + V   +        LA 
Sbjct: 215 PELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILGATAVIAPIPVASRFALFDLPVALAA 274

Query: 77  GITVSILI 84
            +T S+L+
Sbjct: 275 AVTFSVLL 282



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 18/58 (31%), Positives = 29/58 (50%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           +   L + D+ +G+T +A GTS+PE  +SVI A +               F++L  LG
Sbjct: 192 VAQGLGVSDAFIGLTIVAVGTSLPELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILG 249


>UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Prosthecochloris aestuarii DSM
           271|Rep: K+-dependent Na+/Ca+ exchanger related-protein
           - Prosthecochloris aestuarii DSM 271
          Length = 334

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 5/102 (4%)

Query: 276 EKPRFKNWFPLTFIMCIVWIGSLSYIV-AWMITI----IGDTLMIPDSVMGITFLAAGTS 330
           E P  ++  PL   + +V  GS+     AW        I + L IP   +G++ +A GTS
Sbjct: 167 EAPESQDILPLATSISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTS 226

Query: 331 VPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           +PE  +S++ A +               F+IL  LG   +IK
Sbjct: 227 LPELATSLVGAIRRESEISVGNLIGSNIFNILFVLGGVSMIK 268



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 4/47 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPL 64
           PEL  +++G    E +I VG ++GS +FNIL V      G  M+ P+
Sbjct: 228 PELATSLVGAIRRESEISVGNLIGSNIFNILFVLG----GVSMIKPV 270


>UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Desulfuromonas acetoxidans DSM
           684|Rep: K+-dependent Na+/Ca+ exchanger related-protein
           - Desulfuromonas acetoxidans DSM 684
          Length = 314

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 1/94 (1%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +++     E DI +G ++GS +FNIL V   C I   + V      L    +   
Sbjct: 219 PELAASLMSAAKGEMDISIGNVIGSNIFNILFVLGVCPIFQPIAVEPSILRLELPVVMLF 278

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 111
               + +C       +W  A L+VS Y ++I  M
Sbjct: 279 SVALVPLCWHRHVIGRWKGAVLVVS-YVLFIVAM 311



 Score = 34.7 bits (76), Expect = 5.2
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 3/67 (4%)

Query: 304 WMIT---IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFD 360
           WM++   II  ++ + +  +G+T +A GTS+PE  +S++ A +               F+
Sbjct: 188 WMVSSAVIIARSIGLSELFIGMTIVALGTSLPELAASLMSAAKGEMDISIGNVIGSNIFN 247

Query: 361 ILLCLGL 367
           IL  LG+
Sbjct: 248 ILFVLGV 254


>UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;
           n=1; Sulfurovum sp. NBC37-1|Rep: Calcium:H+/Na+
           antiporter, CaCA family - Sulfurovum sp. (strain
           NBC37-1)
          Length = 310

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PE+  ++  +   + +I +  ++GS + NI  V A   + A  + P   +   +D     
Sbjct: 50  PEMAASIAASMNHKPEIAISNVIGSNILNITLVLASVFLIARNISPKRDF-FAKDSTWAL 108

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 114
           + V + I +I D  +  ++A LL+ L G Y+  +  D
Sbjct: 109 VPVLVFILMILDGVISRFDAVLLLLLMGAYLLFLLQD 145



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 3/95 (3%)

Query: 286 LTFIMCIVWIGSLSY---IVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           + F++ ++ +G+L +   ++      I     IP+ ++G T +A GTS+PE  +S+  + 
Sbjct: 1   MNFVIFVIAMGALIWGAELIIKQSEKIALKFNIPEFIIGATLIALGTSLPEMAASIAASM 60

Query: 343 QXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTP 377
                            +I L L   +LI  +++P
Sbjct: 61  NHKPEIAISNVIGSNILNITLVLASVFLIARNISP 95


>UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1;
           Planctomyces maris DSM 8797|Rep: Sodium/calcium
           exchanger protein - Planctomyces maris DSM 8797
          Length = 368

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG 59
           PEL V+V GT   +GD+ VG  +GS + NI  +   C +  G
Sbjct: 74  PELMVSVTGTLAGKGDLAVGNALGSCLCNIGLIIGSCALLKG 115


>UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21;
           Bacteria|Rep: Na+/Ca+ antiporter, CaCA family -
           Roseiflexus sp. RS-1
          Length = 367

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAY 76
           PE+  +++     E DI VG +VGS +FN+L+V     + A   + +    L  D  +  
Sbjct: 227 PEIATSIVAALRGERDIAVGNVVGSNIFNLLSVLGLSSVVAPAGISVAPAALNFDMPVML 286

Query: 77  GITVSILICIIHDEYVQWYEAFLLVSLYGVY 107
            + V+ L        +  +E +L +  Y  Y
Sbjct: 287 AVAVACLPIFFTGRLIARWEGWLFLGYYIAY 317



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 295 IGSLSYIVA---WMI---TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
           IG L+ +V    WM+           + + V+G+T +A GTS+PE  +S++ A +     
Sbjct: 184 IGGLALLVVGSRWMVDGAVSFARVFGVSELVIGLTIVAVGTSLPEIATSIVAALRGERDI 243

Query: 349 XXXXXXXXXTFDILLCLGL 367
                     F++L  LGL
Sbjct: 244 AVGNVVGSNIFNLLSVLGL 262


>UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
           Salinispora|Rep: Na+/Ca+ antiporter, CaCA family -
           Salinispora tropica CNB-440
          Length = 352

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 18/67 (26%), Positives = 37/67 (55%)

Query: 277 KPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVS 336
           + R   W P+  ++ +V + + + ++      I   L +P  V+G+T +A GTS+PE V+
Sbjct: 203 RQRPARWEPVRTVLGLVGVLAGAQLLVVNAAAIATDLGVPQLVIGMTLVAVGTSLPELVT 262

Query: 337 SVIVAKQ 343
           ++   +Q
Sbjct: 263 TIQAQRQ 269


>UniRef50_Q5CI48 Cluster: Cation exchanger; n=2;
           Cryptosporidium|Rep: Cation exchanger - Cryptosporidium
           hominis
          Length = 940

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 19/54 (35%), Positives = 32/54 (59%)

Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAK 342
           IM I W G L   +   I +IG TL I  +++G+T +A G S+ +  ++V V++
Sbjct: 790 IMSIYWNGVLVNELVECIKVIGLTLGIKPAILGLTIVAMGNSIADLFANVAVSR 843


>UniRef50_Q4YXS7 Cluster: Erythrocyte membrane protein 3, putative;
           n=8; Eukaryota|Rep: Erythrocyte membrane protein 3,
           putative - Plasmodium berghei
          Length = 367

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 2/82 (2%)

Query: 157 DVPIEQRHQHNGNIKTSPLRQ-DAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEM 215
           +V +E +   N +++       D K K  E+VDV +K + + + K+K    ++D K  E 
Sbjct: 13  NVDVENKEAENIDVENKEAENVDVKNKEAENVDVENKEAENIDVKNKEAE-NVDVKNKEA 71

Query: 216 EIASPEENLYQPTAEDNTDVED 237
           E    E    + T  +NTDVE+
Sbjct: 72  ENVDVENTNVENTDVENTDVEN 93



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 157 DVPIEQRHQHNGNIKTSPLRQ-DAKEKILESVDVSDKVSASEEGKDKNV-NID---MDSK 211
           +V +E +   N +++ + +   D K K  E+VDV +K + + + ++ NV N D   +D K
Sbjct: 153 NVDVENKEAENVDVENTDVENIDVKNKEAENVDVKNKEAENVDVENTNVENTDVENIDVK 212

Query: 212 PNEMEIASPEENLYQPTAEDNTDVED 237
             E E    E    +    +NTDVE+
Sbjct: 213 NKEAENVDVENKEAENVDVENTDVEN 238



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 30/119 (25%), Positives = 63/119 (52%), Gaps = 7/119 (5%)

Query: 128 VSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQ-DAKEKILES 186
           V N+   N+E ++ +   + K + ++   +  +E     N ++K    +  D K K  E+
Sbjct: 206 VENIDVKNKEAENVD--VENKEAENVDVENTDVENTDVENIDVKNKEAKNIDVKNKEAEN 263

Query: 187 VDVSDKVSASEEGKDKNV-NIDMDSKPNE-MEIASPE-ENLYQPTAE-DNTDVEDGSEN 241
           VDV +K + + + K+K   N+D+ +K  E +++ + + EN+     E +N DV++ +EN
Sbjct: 264 VDVENKEAENIDVKNKEAENVDVKNKEAENVDVENTDVENIDVKNKEAENVDVKNKAEN 322



 Score = 34.7 bits (76), Expect = 5.2
 Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 5/86 (5%)

Query: 157 DVPIEQRHQHNGNIKTSPLRQ-DAKEKILESVDVSDKVSASEEGKDKNV-NIDMDSK-PN 213
           +V +E  +  N +++ + +   D K K  E+VDV +K + + + K+K   N+D+++K   
Sbjct: 73  NVDVENTNVENTDVENTDVENIDVKNKEAENVDVKNKEAKNIDVKNKEAENVDVENKEAK 132

Query: 214 EMEIASPE-ENLYQPTAE-DNTDVED 237
            +++ + E EN+     E +N DVE+
Sbjct: 133 NIDVKNKEAENVDVKNKEAENVDVEN 158


>UniRef50_A2G605 Cluster: Putative uncharacterized protein; n=1;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 1369

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 24/91 (26%), Positives = 50/91 (54%), Gaps = 2/91 (2%)

Query: 160  IEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIAS 219
            ++   QH+   + SP    ++EKI E  +  +++    E K++NVN  +++     EI  
Sbjct: 1103 MDSESQHSQK-ENSPSLLVSEEKIPEIKENQNEIQTFVEQKEENVNQSIETNNVNDEIPQ 1161

Query: 220  PEENLYQPTAEDNTDVEDGSENSLWKWPSNK 250
             EE + +  ++ ++D+++ SENS  K  +N+
Sbjct: 1162 NEEKISE-ISKISSDIQENSENSTEKVENNE 1191


>UniRef50_Q59TE2 Cluster: Putative uncharacterized protein SWI3;
           n=2; Candida albicans|Rep: Putative uncharacterized
           protein SWI3 - Candida albicans (Yeast)
          Length = 1096

 Score = 37.9 bits (84), Expect = 0.55
 Identities = 27/106 (25%), Positives = 57/106 (53%), Gaps = 6/106 (5%)

Query: 133 KDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDK 192
           K+NE++Q  ++  +   S + ++ +   +  + ++ + + S    D +  I ++ DV D 
Sbjct: 233 KNNEQQQQDDDDAE---SENKVESNEHQDNVNSNDNSKQDSNSDNDMQFDIPDAPDVID- 288

Query: 193 VSASEEGKDKNVNIDMDSKPNEMEIASPEE-NLYQPTAEDNTDVED 237
            SASE GK +  N+D D   ++M++  P+E ++   T   NT+ E+
Sbjct: 289 -SASESGKQEPTNVDADDNQDKMDVDIPQETSIAFTTNTQNTNTEE 333


>UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Clostridium oremlandii OhILAs|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Clostridium oremlandii OhILAs
          Length = 310

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL   ++       DI VG I+GS +FNIL V +     + ++ P+ +       LA+ 
Sbjct: 215 PELITCLVACHKKNDDIAVGNIIGSNIFNILFVLSV----SSLISPIAFSSHLIIDLAFM 270

Query: 78  ITVSILICIIH--DEYVQWYEAFLLVSLYGVYICIMY 112
           +  + L+ I     + +   E F+L+ LY  Y   +Y
Sbjct: 271 LLFTFLLFIFSYTHKKISRLEGFVLMMLYLFYFVFIY 307


>UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Hyphomonas neptunium ATCC
           15444|Rep: K+-dependent Na+/Ca+ exchanger
           related-protein - Hyphomonas neptunium (strain ATCC
           15444)
          Length = 339

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 19/58 (32%), Positives = 32/58 (55%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           I ++V+G+T +A GTS+PE  +SV+ A +               F+IL  LG+  L++
Sbjct: 203 ISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGNVIGSNLFNILGILGITALVQ 260



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 13/33 (39%), Positives = 22/33 (66%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 50
           PEL  +V+  F  + D+ +G ++GS +FNIL +
Sbjct: 220 PELATSVVAAFRKKADVALGNVIGSNLFNILGI 252


>UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2;
           Hyphomonadaceae|Rep: Sodium/calcium exchanger -
           Oceanicaulis alexandrii HTCC2633
          Length = 334

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 11/69 (15%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV-----------VPLDW 66
           PEL   ++     + D+ +G +VGS +FNI AV    G+ A              + LD+
Sbjct: 226 PELATALVAALRKQADMAIGNVVGSNIFNISAVGGITGLAASFATGQPAPVSDQFIQLDF 285

Query: 67  WPLTRDCLA 75
           W +T   LA
Sbjct: 286 WVMTAAALA 294



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 20/65 (30%), Positives = 30/65 (46%)

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           T +     +P  ++G+T +A GTS PE V S   A +                ++LL LG
Sbjct: 30  TALASKAGVPPLLVGLTIVAFGTSAPEMVVSAAAAVEGAPGLAIGNIVGSNIANVLLVLG 89

Query: 367 LPWLI 371
           LP L+
Sbjct: 90  LPALL 94



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 1/66 (1%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
           +PD+V+G+T LA GTS+PE  ++++ A +               F+I    G+  L  AS
Sbjct: 209 VPDAVIGLTILAFGTSLPELATALVAALRKQADMAIGNVVGSNIFNISAVGGITGL-AAS 267

Query: 375 LTPAEP 380
               +P
Sbjct: 268 FATGQP 273


>UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein
           precursor; n=3; Gammaproteobacteria|Rep: Na+/Ca+
           antiporter, CaCA family protein precursor - Psychromonas
           ingrahamii (strain 37)
          Length = 320

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 5/71 (7%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLT-RDCLAY 76
           PEL V+V      + DI +G +VGS + NIL +   C +    + PL   PL  R   A 
Sbjct: 51  PELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGICAV----ITPLAVKPLVLRRDAAT 106

Query: 77  GITVSILICII 87
            +  SIL  I+
Sbjct: 107 VVAASILFLIL 117



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 19/59 (32%), Positives = 31/59 (52%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           I +   +P++V+G+T +A GTS+PE   SVI A +               F++L  LG+
Sbjct: 199 IAEHFNVPEAVIGLTLVAIGTSLPELSISVIAAIRRHADVAVGNILGSNIFNLLGILGV 257



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 14/33 (42%), Positives = 21/33 (63%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 50
           PEL ++VI       D+ VG I+GS +FN+L +
Sbjct: 222 PELSISVIAAIRRHADVAVGNILGSNIFNLLGI 254


>UniRef50_A2Q9Q0 Cluster: Contig An01c0300, complete genome; n=1;
           Aspergillus niger|Rep: Contig An01c0300, complete genome
           - Aspergillus niger
          Length = 429

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 3/119 (2%)

Query: 135 NEEKQDAENGKDLKLSTHILKIDVPIEQRHQHN--GNIKTSPLRQDAKEKILESVDVSDK 192
           +E   ++  GK  + +  +      +E+  Q+       +S   QD+ E+ L+   +  +
Sbjct: 179 DESAPESRPGKQTRTAAVLSSGKDQVEETDQNGMTDEDSSSDYEQDSDEETLQGPSLPFE 238

Query: 193 VSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKS 251
              S++G +  V  D ++ P   +    E  +++P AE+NTD E  S +++   P  KS
Sbjct: 239 EEESQDGIETIVIDDGNNDPESHQNGEEEAEVHRPDAEENTD-EPVSRSTVRLMPGRKS 296


>UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2;
           Methanosarcinaceae|Rep: Sodium/calcium exchanger protein
           - Methanosarcina acetivorans
          Length = 315

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 20/78 (25%), Positives = 40/78 (51%), Gaps = 5/78 (6%)

Query: 295 IGSLSYIVAWMITI-----IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXX 349
           +GSLS ++   I +     I + + IP+ ++ +T +A GTS+PE V+++   ++      
Sbjct: 176 LGSLSVVIGSRILVDSGIKIAEWIGIPEVIIALTAVAIGTSLPELVTAIASLRKGHQDLS 235

Query: 350 XXXXXXXXTFDILLCLGL 367
                   T D+ + LG+
Sbjct: 236 IGNILGANTMDVAMILGV 253


>UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           Na(+)/Ca(2+) antiporter - Uncultured methanogenic
           archaeon RC-I
          Length = 308

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 4/91 (4%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PE+   ++ +   EGD+ +G  +GS + N L +       A +V PL    +    +  G
Sbjct: 213 PEMVTALVASRKDEGDLVMGNCIGSVIVNTLFILG----AAAIVSPLPIAGVIDILILLG 268

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLYGVYI 108
           I V +L  ++    +   E  LLV LY +++
Sbjct: 269 IIVLLLPILVTRSQIGHREGILLVVLYVIFV 299



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLM---IPDSVMGITFLAAGTSVPEAVSSV 338
           L  I  +V IG L     W++    D      IP SV+G+T +A GTSVPE V  +
Sbjct: 5   LELIGLLVGIGLLVKGADWLVESARDLAFAAGIPASVIGLTLVAMGTSVPEFVVGI 60


>UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep: Na+/Ca+
           antiporter, CaCA family - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 296

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 18/43 (41%), Positives = 26/43 (60%), Gaps = 3/43 (6%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
           PEL  ++I       DIGVG I+GS ++NIL +    G+GA +
Sbjct: 203 PELITSIIAIRKGHSDIGVGNIIGSNIYNILMI---MGVGAAL 242



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 16/76 (21%), Positives = 40/76 (52%), Gaps = 2/76 (2%)

Query: 292 IVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXX 351
           ++++G+L  +      I+     + + ++G+T +A GTS+PE ++S+I  ++        
Sbjct: 165 LLYVGAL--LTVDNAVILAKEFGLSEKIIGLTVIAIGTSLPELITSIIAIRKGHSDIGVG 222

Query: 352 XXXXXXTFDILLCLGL 367
                  ++IL+ +G+
Sbjct: 223 NIIGSNIYNILMIMGV 238


>UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1;
           Methanobrevibacter smithii ATCC 35061|Rep: Ca2+/Na+
           antiporter - Methanobrevibacter smithii (strain PS /
           ATCC 35061 / DSM 861)
          Length = 313

 Score = 37.5 bits (83), Expect = 0.73
 Identities = 21/64 (32%), Positives = 31/64 (48%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           I   L IP  ++G+T +A GTS PEA  S+  + Q               F+IL  +G+ 
Sbjct: 32  IATILKIPTLIVGLTIVAFGTSAPEAAVSISSSIQGSNALAVSNVIGSNIFNILGIIGIC 91

Query: 369 WLIK 372
            L+K
Sbjct: 92  ALLK 95



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 17/51 (33%), Positives = 28/51 (54%)

Query: 317 DSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
           ++++G+T +A GTS+PE V+S+   K+               F+IL  LGL
Sbjct: 203 ETLVGLTIVAIGTSLPELVTSLTALKRDENQLVIGNVIGSNIFNILFVLGL 253


>UniRef50_UPI00004D858F Cluster: serine arginine-rich pre-mRNA
           splicing factor SR-A1; n=2; Xenopus tropicalis|Rep:
           serine arginine-rich pre-mRNA splicing factor SR-A1 -
           Xenopus tropicalis
          Length = 1130

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 7/120 (5%)

Query: 135 NEEKQDAENGKDLKLSTHILKID-VPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKV 193
           + E++D E  +  +L     K+D  P+ +R + +      P  QD     L S+  +  V
Sbjct: 513 SNERRDKEKVRS-RLPVDEPKLDNPPLLERRRRDSRSVVPPSIQDLNNADLFSIKRTITV 571

Query: 194 SASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAED--NTDVEDGSENSLWKWPSNKS 251
           +  E+  D+    D+ + P + E+    E L   T  D  N D  DG  N +++ PS KS
Sbjct: 572 NPEEKLDDRE---DLLNTPRKREVLYDSEGLSFDTFSDRENLDDRDGKSNRIFERPSGKS 628


>UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=11; Proteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Azotobacter vinelandii AvOP
          Length = 360

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 17/33 (51%), Positives = 22/33 (66%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 50
           PEL  +++     E DI VG IVGS +FN+LAV
Sbjct: 225 PELATSLVAAIKGERDIAVGNIVGSNIFNLLAV 257



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 7/70 (10%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PE+ V+V      +GDI VG  +GS +FN+L +    G+ A +V+PL    ++R  + + 
Sbjct: 53  PEMAVSVRSASGGQGDIAVGNAIGSNIFNVLMI---LGLSA-LVIPL---RVSRQLIRFD 105

Query: 78  ITVSILICII 87
           + V I + ++
Sbjct: 106 VPVMIGVSLL 115



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 19/68 (27%), Positives = 33/68 (48%)

Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           L + +  +G+T +AAGTS+PE  +S++ A +               F++L  LGL  L+ 
Sbjct: 206 LGLSELAIGLTMVAAGTSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAVLGLAALVS 265

Query: 373 ASLTPAEP 380
            +     P
Sbjct: 266 PAPIEVSP 273



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 9/93 (9%)

Query: 285 PLTFIMCIVWIGSLSYIVAWMITIIGDTLM------IPDSVMGITFLAAGTSVPEAVSSV 338
           PLTFI C+  I  L+ ++A    ++           IP  ++G+T +A GTS PE   SV
Sbjct: 3   PLTFI-CL--IAGLALLIAGAEALVRGAARLAARFGIPPLIIGLTVVAFGTSAPEMAVSV 59

Query: 339 IVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
             A                 F++L+ LGL  L+
Sbjct: 60  RSASGGQGDIAVGNAIGSNIFNVLMILGLSALV 92


>UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Fervidobacterium nodosum Rt17-B1|Rep: Na+/Ca+
           antiporter, CaCA family - Fervidobacterium nodosum
           Rt17-B1
          Length = 314

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 287 TFIMCIVWIGSLSYIV---AWMIT---IIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIV 340
           T I  +  IG L+ +V    W++     I     + D ++G+T +AAGTS+PE  +S+  
Sbjct: 169 TIISILYIIGGLAGLVFGGRWIVNGAVDIAKAFGVSDKLIGLTIVAAGTSIPELATSLAA 228

Query: 341 AKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
             +               F++   LG+  +IK
Sbjct: 229 IIKGNNEIALGNAVGSNIFNVFFILGISAVIK 260



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 15/45 (33%), Positives = 26/45 (57%)

Query: 18 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 62
          PEL VN++ +     +I +G ++GS +FNIL V     +   ++V
Sbjct: 52 PELAVNIVSSIKGTSNISLGNVIGSNIFNILVVVGLSAVIRPVIV 96



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP-LTRDCLAY 76
           PEL  ++        +I +G  VGS +FN+  +    GI A ++ P+ +   L  D    
Sbjct: 220 PELATSLAAIIKGNNEIALGNAVGSNIFNVFFI---LGISA-VIKPIVYTTVLNFDVTLL 275

Query: 77  GITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 113
            I   IL+    +  ++ +E  L+VS Y  Y   + Y
Sbjct: 276 VIITVILLLFSKNLKIEKFEGLLMVSTYVGYTIYLIY 312


>UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=5; Bacteria|Rep: K+-dependent Na+/Ca+
           exchanger related-protein - Pseudomonas stutzeri (strain
           A1501)
          Length = 361

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 5/45 (11%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 62
           PEL  +V+     E DI VG +VGS +FN+L V     +GAG  V
Sbjct: 226 PELATSVLAVIKGERDIAVGNVVGSCIFNLLLV-----LGAGAAV 265



 Score = 33.9 bits (74), Expect = 9.0
 Identities = 17/45 (37%), Positives = 25/45 (55%)

Query: 18 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 62
          PE  V+V  +    GDI VG ++GS + NIL +     + A +VV
Sbjct: 53 PETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLSALIAPLVV 97


>UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Parvularcula bermudensis
           HTCC2503|Rep: K+-dependent Na+/Ca+ exchanger
           related-protein - Parvularcula bermudensis HTCC2503
          Length = 327

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 1/73 (1%)

Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
           I   L IP  ++G+T +A GTS PE V S+                     ++ L LGLP
Sbjct: 29  IATRLGIPSLLIGLTIVAFGTSAPELVVSINAVVTGDNGIAVGNIVGSNIANVFLVLGLP 88

Query: 369 WLIKASLTPAEPG 381
            LI A ++ + PG
Sbjct: 89  ALISA-ISLSGPG 100


>UniRef50_A7NTE6 Cluster: Chromosome chr18 scaffold_1, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr18 scaffold_1, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 778

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 25/68 (36%), Positives = 40/68 (58%), Gaps = 4/68 (5%)

Query: 184 LESVDVSDKVSASEEGKDKNVNIDMDS-KPNEMEIASPEENLYQPTAEDNTDVEDGSENS 242
           L+S  V D VS++EE  DK  NID D  +P E+  +SP+ +  +   +D  + ED S+N 
Sbjct: 396 LDSAPVDD-VSSNEEDNDKE-NIDPDPHRPIEL-CSSPKGDPVKAFVDDEAEEEDDSDND 452

Query: 243 LWKWPSNK 250
           L ++  N+
Sbjct: 453 LIRFQENE 460


>UniRef50_Q6CSX0 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome C of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome C of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 768

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 115 KPIQNFAKGSWKWVSNMFKDNE--EKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKT 172
           K I+N  K + KW +   K+N   E    ENGK L     +L+  +   Q  + N N + 
Sbjct: 427 KRIENLNKETAKWKNESQKNNGNLESYIKENGK-LSERLEVLQEKLETLQNLKSNSNDQV 485

Query: 173 SPLRQDAKEKILESVDVSDKVSASEEGKDKNVNI 206
             +R+  +E   +  D + K+ + E+  ++N NI
Sbjct: 486 ETIRKQCEELSFKLKDANKKILSLEDELNENANI 519


>UniRef50_A7THF3 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 1204

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 161 EQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKD--KNVNIDMDSKPN-EMEI 217
           EQRHQH+ + +     Q++  ++ +  + + K+   +   +  KN NI+ DS P   +  
Sbjct: 188 EQRHQHSYHKEDQITGQNSHSQVSDEEEANAKIEQDKSSSEVNKNKNIENDSNPTISLSR 247

Query: 218 ASPEENLYQPTAEDNTDVEDGSEN 241
              +  L  PT  +  D+E G  +
Sbjct: 248 TQLKSMLTDPTEIERKDIEAGQSS 271


>UniRef50_Q9NEU2 Cluster: Protein SDA1 homolog; n=4;
           Caenorhabditis|Rep: Protein SDA1 homolog -
           Caenorhabditis elegans
          Length = 801

 Score = 37.1 bits (82), Expect = 0.97
 Identities = 21/83 (25%), Positives = 41/83 (49%)

Query: 179 AKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDG 238
           AK+K +E   V +   +  + ++     +MD +  E+EI+  EE      AE+   VE+ 
Sbjct: 571 AKKKRVEQKSVENDAESDADDEEIEDEEEMDDEEEEIEISDEEEEEIDDEAEEEAVVEEE 630

Query: 239 SENSLWKWPSNKSCLAKITKIVT 261
           +  ++ K P  K+    + +I+T
Sbjct: 631 ASEAVEKDPKLKASKNSMDRIMT 653


>UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan
           hydroxylase D1; n=7; Danio rerio|Rep: PREDICTED: similar
           to tryptophan hydroxylase D1 - Danio rerio
          Length = 488

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 29/124 (23%), Positives = 67/124 (54%), Gaps = 8/124 (6%)

Query: 134 DNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQ--DAKEKILESVDVS- 190
           +NEEK++ +N + +K++   +K +   E++++    +    +++  + +EK  E V ++ 
Sbjct: 217 ENEEKEE-KNEEMVKMNKDRIKENEEKEEKNEEMVKMNKDRMKENEEKEEKNEEMVKMNE 275

Query: 191 DKVSASEEGKDKN----VNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKW 246
           D++  +EE ++KN    +  +M S+ +E+E  + E  + +    DN +VE+ +E    K 
Sbjct: 276 DRMKENEEKEEKNEEMVIKEEMISENDEVEEENEEMVIKEEMITDNDEVEEENEEEREKT 335

Query: 247 PSNK 250
              K
Sbjct: 336 KKEK 339


>UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6;
           Bacteria|Rep: Sodium/calcium exchanger - Shewanella
           oneidensis
          Length = 316

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 16/39 (41%), Positives = 22/39 (56%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 56
           PEL  +V+     + DI +G IVGS +FNIL +     I
Sbjct: 215 PELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAI 253



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 17/57 (29%), Positives = 31/57 (54%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLI 371
           + + ++G+T +A GTS+PE V+SV+ A +               F+IL  LG+  ++
Sbjct: 198 VSEIIIGLTIVAIGTSMPELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAIV 254


>UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=17; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Silicibacter
           pomeroyi
          Length = 319

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 17/61 (27%), Positives = 33/61 (54%)

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           +II  T  + ++V+G+T +A GTS+PE  ++V+ A +               F++L  +G
Sbjct: 200 SIIARTYGVSETVIGLTLVAVGTSLPELATTVMAALRRQADVALGNVIGSNMFNLLAIIG 259

Query: 367 L 367
           +
Sbjct: 260 V 260



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           L +P  ++ +T +A GTS PE + S+    +              T +ILL LG+P L+ 
Sbjct: 32  LGVPALIVSLTIVAFGTSAPELLISIKAVLEHAPGIALGNVVGSNTANILLVLGVPALL- 90

Query: 373 ASLTPAE 379
           A+L  +E
Sbjct: 91  ATLHTSE 97


>UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1;
           Aquifex aeolicus|Rep: Putative uncharacterized protein -
           Aquifex aeolicus
          Length = 322

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 21/58 (36%), Positives = 30/58 (51%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           IP+ V+G+T +A GTS+PE   +V  A +                +ILL LG+  LIK
Sbjct: 35  IPEFVIGLTLVAFGTSLPEFTVNVSAALKDASGISLGNVIGSNIANILLILGVASLIK 92


>UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Na+/Ca+
           antiporter, CaCA family - Alkaliphilus metalliredigens
           QYMF
          Length = 334

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 21/82 (25%), Positives = 40/82 (48%)

Query: 286 LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX 345
           + FI+  V+I   + ++     II + L +P+ V+ +T +A GTS+PE  +++    +  
Sbjct: 176 IMFIVGAVFIALGARLLVNNGVIIANILGVPEQVVSLTLIALGTSLPELTTAISSVVKGH 235

Query: 346 XXXXXXXXXXXXTFDILLCLGL 367
                         DI++ LGL
Sbjct: 236 QGISVGNILGANILDIVMVLGL 257


>UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; Psychrobacter|Rep: Na+/Ca+ antiporter, CaCA family
           precursor - Psychrobacter sp. PRwf-1
          Length = 322

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 287 TFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXX 346
           T I+ +  + + S  + W    +     + + ++G+T +A GTS+PE V+SV  A++   
Sbjct: 175 TLILGLSLLIASSRAIVWGAVELATLWGMSELLIGLTIVAIGTSLPELVASVAAARRGEH 234

Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIK 372
                       F+ L  +GL  +IK
Sbjct: 235 DMALGNVIGSNLFNTLGVVGLAAIIK 260



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 2/70 (2%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +V      E D+ +G ++GS +FN L V     I   M   +D   L+RD +  G
Sbjct: 220 PELVASVAAARRGEHDMALGNVIGSNLFNTLGVVGLAAIIKPM-QHIDPQILSRDVMMVG 278

Query: 78  ITVSILICII 87
           + VS+L+ I+
Sbjct: 279 M-VSVLLFIL 287


>UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1;
           Algoriphagus sp. PR1|Rep: Sodium/calcium exchanger -
           Algoriphagus sp. PR1
          Length = 312

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 17/58 (29%), Positives = 30/58 (51%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
           + + V+GIT +A GTS+PE ++S++ A                  ++L  LG+  +IK
Sbjct: 202 VSERVIGITIIAIGTSLPELITSIMAALSKKTDMAIGNILGSNIMNVLSILGITAIIK 259



 Score = 35.5 bits (78), Expect = 3.0
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 5/108 (4%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL V+V        DI VG ++GS + NI  V    G+   +++      L  D     
Sbjct: 51  PELLVSVNAALKGNSDISVGNVIGSNIANIGMVLGISGLFYPILIRKS--TLRFDYFITV 108

Query: 78  ITVSILICIIHDEYVQWYEAFLLVSLY-GVYICIMYYDKPIQNFAKGS 124
           +   +   + ++  ++ +E  LL SL+ G  + +  Y    Q  A+GS
Sbjct: 109 LVTLLFYAVSYNGMIELWEGILLFSLFIGFNLYLFKYTD--QGLAEGS 154


>UniRef50_Q55CW2 Cluster: SAM domain-containing protein; n=1;
           Dictyostelium discoideum AX4|Rep: SAM domain-containing
           protein - Dictyostelium discoideum AX4
          Length = 875

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 11/150 (7%)

Query: 100 LVSLYGVYICIMYYDKPIQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVP 159
           ++  YG Y    YY    + + KGS K  S     NE       GK LK   ++  +D P
Sbjct: 237 IIKTYGYYKDENYYYVASKFYPKGSIKTKSKSTPYNEINAKKVFGKVLKAIDYLHSLDPP 296

Query: 160 IEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIAS 219
           I  R  ++ NI    L  +  E IL    +S K     E KD N N D D+  N     +
Sbjct: 297 IIHRDINSDNI----LFDENDEPILIDFGLSYK-----ELKDDN-NNDDDNYDNHNHNHN 346

Query: 220 PEENLYQPTAEDN-TDVEDGSENSLWKWPS 248
              N       DN T+V+  ++    +WPS
Sbjct: 347 HNHNHNHDNDNDNDTNVKIKTQCMEPRWPS 376


>UniRef50_A2FNC4 Cluster: Variable membrane protein, putative; n=1;
            Trichomonas vaginalis G3|Rep: Variable membrane protein,
            putative - Trichomonas vaginalis G3
          Length = 2191

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 5/118 (4%)

Query: 133  KDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDK 192
            K +EEK++ EN +    +  I   +V  E+  + +   K     +D K   +ES    D+
Sbjct: 1659 KSDEEKKEEENPQ--AQTKEIDLNEVHPEEEKKSDEEKKDEKSDEDVK---IESDKSEDE 1713

Query: 193  VSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNK 250
                EE K  + +I +DS  ++ E   PEE       E  +D E+  + +  K P N+
Sbjct: 1714 KKPEEEKKSDDEDIKIDSDKSDDEEKKPEEEKKSDNEERKSDHEEEKKENEEKEPENE 1771



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 25/109 (22%), Positives = 48/109 (44%), Gaps = 2/109 (1%)

Query: 134  DNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKV 193
            + E+K + E   + K S   +KI+   E+  Q          + D + K+ +S +  +K 
Sbjct: 1131 EEEKKSEEEKPTEEKKSDEEIKIEKSSEEEKQDEEKKPEEEKKSDEEIKVEKSSE-EEKK 1189

Query: 194  SASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENS 242
               E+  D+ + I+  S+  E ++   +    +PT E  +D E   E S
Sbjct: 1190 PEEEKKSDEEIKIEKSSE-EEKQVEEKKSEEEKPTEEKKSDEEIKVEKS 1237



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 133  KDNEEKQDAENGKD--LKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVS 190
            K  EEK+  E  KD  +K+      ++   E++ Q     +     ++ K    ES D  
Sbjct: 1466 KPEEEKKSDEEVKDREIKIEEETQPVEENKEEKLQEEEKKEEEKPVEEKKSDDFESDDKK 1525

Query: 191  DKVSASEEGKDKNVNI---DMDSKPNEMEIASPEENLYQPTAEDNTDVE 236
             +    EE  DK + I   D + KP E E   PEE   +   E+N  VE
Sbjct: 1526 SEEEKKEEKSDKEIKIEKSDEEEKPAEEE-KKPEEE--EKKEEENPPVE 1571


>UniRef50_A2E032 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 1042

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 5/113 (4%)

Query: 129 SNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVD 188
           S+  KDNE +Q  EN ++ +     +   +  +   Q   N +TSP  +  KE+I +  +
Sbjct: 393 SSSQKDNENEQKLENSQEPRTQKEEIAETIQEDTEKQQENN-ETSP--EPVKEEIND--E 447

Query: 189 VSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSEN 241
              ++S S + + +  NI    + N+    S +E   Q T   N + E  +EN
Sbjct: 448 EQKEISNSTQNELEPENIPEQEQENQEVTESVKELNQQKTESQNPEQEQNTEN 500


>UniRef50_Q5A5C0 Cluster: Potential Sit4 phosphatase complex
           component; n=3; Saccharomycetales|Rep: Potential Sit4
           phosphatase complex component - Candida albicans (Yeast)
          Length = 861

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 1/97 (1%)

Query: 165 QHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENL 224
           + N +IK S  + D KE   +   V  K S S+  KDK V+ ++  K +E E    ++N 
Sbjct: 88  EDNPSIKDSKNKIDTKESTSDRKTVEKKSSKSDSKKDKTVD-NVKEKGDEKEKGDEKDNE 146

Query: 225 YQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVT 261
                ED+ D ++   + + +    +S   K T+  T
Sbjct: 147 DDDDDEDDDDDDEEKNDEIDEQDLEESAEQKATRRAT 183


>UniRef50_A5E2T9 Cluster: Putative uncharacterized protein; n=2;
           Fungi/Metazoa group|Rep: Putative uncharacterized
           protein - Lodderomyces elongisporus (Yeast)
           (Saccharomyces elongisporus)
          Length = 1068

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 20/81 (24%), Positives = 40/81 (49%)

Query: 161 EQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASP 220
           E+R+  N N K    ++  KEK  E  +  ++    EE +++   + M+SK N+ +  + 
Sbjct: 427 EKRNNDNNNKKKKKKKKKKKEKEEEEEEEEEEEEEEEEEEEEKEKMMMNSKTNDGDDENE 486

Query: 221 EENLYQPTAEDNTDVEDGSEN 241
           E+   + T  +N +    S+N
Sbjct: 487 EDKKIEDTDNENKENSLSSQN 507


>UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:
           NEQ486 - Nanoarchaeum equitans
          Length = 308

 Score = 36.7 bits (81), Expect = 1.3
 Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 9/101 (8%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PL--DWWPLTRDCL 74
           PEL V ++     + +I +G I+GS   N+       G+G G+++ PL      L  +  
Sbjct: 56  PELAVAILAALDNKSEIVLGDIIGSNFANL-----GLGLGIGLIISPLVIKKETLFNEVP 110

Query: 75  AYG-ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 114
            +G IT++ L+ I++D  +  YEA  ++  + + +  +Y D
Sbjct: 111 IHGAITLATLLLILNDSVLDKYEALTILIFFALMLLNIYKD 151


>UniRef50_UPI000150A186 Cluster: Zinc finger, C2H2 type family
           protein; n=1; Tetrahymena thermophila SB210|Rep: Zinc
           finger, C2H2 type family protein - Tetrahymena
           thermophila SB210
          Length = 577

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 4/102 (3%)

Query: 126 KWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQH-NGNIKTSPLRQDAKEKIL 184
           K +SN  K++E KQ    G   KLS     ++  +EQ +   N N+ +  L Q+ K K  
Sbjct: 85  KVISNSLKEHESKQTNHLGNHEKLSKTQHTLNKSLEQSYSDINNNLSSQSLSQNTKIKKE 144

Query: 185 ESVDVSDKVSASE-EGKDKNVNIDMDSKPNEMEIASPEENLY 225
           ES + SD+ +  E +   ++ N  + SK  E +    +EN Y
Sbjct: 145 ESENQSDQQTQIENQSHIQDQNQKLISK--EKQDGKDKENGY 184


>UniRef50_Q4A126 Cluster: Putative uncharacterized protein; n=1;
           Staphylococcus saprophyticus subsp. saprophyticus ATCC
           15305|Rep: Putative uncharacterized protein -
           Staphylococcus saprophyticus subsp. saprophyticus
           (strain ATCC 15305 /DSM 20229)
          Length = 357

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 33/124 (26%), Positives = 60/124 (48%), Gaps = 9/124 (7%)

Query: 112 YYDKPIQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIK 171
           Y+ K  Q +   S +  SN  +   EK++ +   + K ST   K D  ++Q  +   NI+
Sbjct: 215 YWQKE-QGYDNESNQSTSNNNQSQNEKENNQTSDNSKQST---KKDAKVDQNRE---NIE 267

Query: 172 TSPLRQDAKEKILESVDVS-DKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAE 230
           T+    + K+   E  + S ++ S +EE +D N  I+  S  ++    + +EN  Q   +
Sbjct: 268 TNNDESNQKQNNEEQQENSNEEASQNEEREDPNQQIEQPSSEDKQNPDAAQENNNQ-NND 326

Query: 231 DNTD 234
           +NTD
Sbjct: 327 ENTD 330


>UniRef50_Q8KK76 Cluster: Putative uncharacterized protein orf66;
           n=1; Proteus vulgaris|Rep: Putative uncharacterized
           protein orf66 - Proteus vulgaris
          Length = 279

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 8/108 (7%)

Query: 227 PTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNW--- 283
           P   D      GS  SL+    N   L   T  +  P+ L+F+ T+  CE   F+N+   
Sbjct: 157 PLVMDPVSQPQGSL-SLFPVYFNMYSLVTFTTFIILPMMLMFIGTVVRCESSLFRNFKTV 215

Query: 284 ----FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAA 327
               F    IM I+ + SL+ +  W  T +    ++  S++ I  L A
Sbjct: 216 FLAVFRNVSIMIIIAMLSLAVLALWSYTSLNSDWLVFSSIVPIALLTA 263


>UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: Na+/Ca+
           antiporter, CaCA family - Parvibaculum lavamentivorans
           DS-1
          Length = 350

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 307 TIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLG 366
           T I     + D+V+G++ +A GTS+PE  +SV+   +                +IL  LG
Sbjct: 223 TEIAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAILG 282

Query: 367 LPWLIKASLTPAEPG----HYWVKI 387
           +  LI A L P +P     H WV +
Sbjct: 283 VTALI-APL-PIDPDFLRFHLWVML 305



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 7/70 (10%)

Query: 18  PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 77
           PEL  +V+  F    D+ VG I+GS + NILA+    G+ A ++ PL   P+  D L + 
Sbjct: 248 PELATSVMAVFRRNNDMVVGNIIGSNIMNILAI---LGVTA-LIAPL---PIDPDFLRFH 300

Query: 78  ITVSILICII 87
           + V +   ++
Sbjct: 301 LWVMLAAVVM 310


>UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; Erythrobacter|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Erythrobacter sp.
           NAP1
          Length = 328

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
           +P++V+G+T +A GTS+PE  +S+  A +               ++ILL  G    I   
Sbjct: 197 VPETVIGLTVVAIGTSLPELAASIAAALRGKSGLAIGNVLGSNIYNILLIGGATMSIAPF 256

Query: 375 LTPAE 379
             P E
Sbjct: 257 ALPQE 261


>UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Rep:
           F15I1.21 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 644

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)

Query: 265 HLVFLFTIPDCEKPRFK-NWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGIT 323
           +L F  T PD     +   W    FIM IVW   ++  +  ++   G    I  S++G+T
Sbjct: 461 YLAFKNTEPDRPPQIYLIPWVLGGFIMSIVWFYMIANELVALLVTFGGIYGINPSILGLT 520

Query: 324 FLAAGTSVPEAVSSVIVA 341
            LA G S+ + VS++ ++
Sbjct: 521 VLAWGNSMGDLVSNIALS 538


>UniRef50_Q337V5 Cluster: Sodium/calcium exchanger protein,
           expressed; n=8; Oryza sativa|Rep: Sodium/calcium
           exchanger protein, expressed - Oryza sativa subsp.
           japonica (Rice)
          Length = 597

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 24/120 (20%), Positives = 50/120 (41%), Gaps = 5/120 (4%)

Query: 266 LVFLFTIPDCEKP-RFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITF 324
           + F  T PD         W    F+M + W  +++  +  ++      + +  + +G+T 
Sbjct: 417 VAFFTTSPDAPPADHLAAWLAAGFVMSVAWAYAVATELLALLVSAAHVMGVDSAALGLTV 476

Query: 325 LAAGTSVPEAVSSVIVAKQXXXXXXXXXXXX----XXTFDILLCLGLPWLIKASLTPAEP 380
           LA G S+ + V+++ VA +                   FD+L+ LG+  L+ +  +   P
Sbjct: 477 LAWGNSLGDLVANLAVASRGGGGGGAQVAVAGCYGGPVFDVLVGLGVSMLLSSWASHPRP 536


>UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:
           ENSANGP00000016911 - Anopheles gambiae str. PEST
          Length = 563

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 13/33 (39%), Positives = 20/33 (60%)

Query: 22  VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
           + ++      GD+G GTIVGSA +N+  + A C
Sbjct: 147 IEIVAKNFNAGDLGPGTIVGSAAYNLFVIMAIC 179


>UniRef50_Q6LFD0 Cluster: Putative myosin-like protein; n=2; cellular
            organisms|Rep: Putative myosin-like protein - Plasmodium
            falciparum (isolate 3D7)
          Length = 2153

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 29/136 (21%), Positives = 64/136 (47%), Gaps = 12/136 (8%)

Query: 112  YYDKPIQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHIL-KIDVPIEQRHQHNGNI 170
            +++  IQNF      +  +  + ++  +  E  KD + + +    IDV   +  + N ++
Sbjct: 1214 FFNMGIQNFYNKKKNFFLDSKRGSDASKKGEENKDEQENKNEEDNIDVKDNKGEEDNIDV 1273

Query: 171  KTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPT-- 228
            + +   +D       ++DV +  +  E+ KD+ VNID++   N  +    E+N+ +    
Sbjct: 1274 EDNKGEED-------NIDVEENKNV-EDNKDEEVNIDVEENKNVEDNKDVEDNIDEEVNI 1325

Query: 229  -AEDNTDVEDGSENSL 243
              E+N +VED  +  +
Sbjct: 1326 DVEENKNVEDNKDEEV 1341



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 16/114 (14%)

Query: 134  DNEEKQDAENGKDLKLST-HILKIDVP----IEQRHQHNGNIKTSPLRQDAKEKILE-SV 187
            D EE ++ E+ KD++ +    + IDV     +E       NI     +     K  E ++
Sbjct: 1302 DVEENKNVEDNKDVEDNIDEEVNIDVEENKNVEDNKDEEVNIDVEENKNVEDNKDEEVNI 1361

Query: 188  DVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSEN 241
            DV +  +  E+ KD+ VNID++   N       E+NL     EDN DVED   N
Sbjct: 1362 DVEENKNV-EDNKDEEVNIDVEENKN------VEDNL---DVEDNLDVEDNLIN 1405


>UniRef50_Q54G75 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1886

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 28/130 (21%), Positives = 48/130 (36%), Gaps = 4/130 (3%)

Query: 116  PIQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPL 175
            PI    + +   +    +  +++Q+ EN     +   +L I+    Q   HN N     +
Sbjct: 1725 PIPTIGQKNNSQIQQQQQQEQQEQNLENASHYTVKDKVLIIEDNQNQNQNHNQNNNDDNI 1784

Query: 176  RQDAKEKILESVDVSDKVSASEEGKDKNVNID---MDSKPNEMEIASPEENLYQPTAEDN 232
                    +E +   D         D N NI+    D   N  EI   +EN      +D+
Sbjct: 1785 TIKESNTSIEIIQADDNDDDDNNNNDNNNNINEKRNDEDDNSNEIKQNDENEKIEIIQDD 1844

Query: 233  TDVEDGSENS 242
             + ED S N+
Sbjct: 1845 -ETEDLSNNT 1853


>UniRef50_Q23ZF3 Cluster: UV-endonuclease uvde family protein; n=1;
           Tetrahymena thermophila SB210|Rep: UV-endonuclease uvde
           family protein - Tetrahymena thermophila SB210
          Length = 503

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 6/122 (4%)

Query: 122 KGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKE 181
           K   K  S+   D+ +  + EN ++ K  +         +Q+ ++  N+K +   QD + 
Sbjct: 357 KEKTKLKSDCCDDDTDGSEEENNEEQKEESEKQNKKKTTKQQIKNQKNVKQNKDTQDLEV 416

Query: 182 KILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEE-NLY-QPTAEDNTDVEDGS 239
           KI+E  + SD+V   E+ K K  + D+D  P+E  +      N Y Q   + NTD ED  
Sbjct: 417 KIIEKQNKSDQV---EKNKKKQQS-DVDLLPSEKIVRRLRSGNKYTQVLDKTNTDNEDKL 472

Query: 240 EN 241
            N
Sbjct: 473 AN 474


>UniRef50_Q23YU2 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 2381

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 4/67 (5%)

Query: 142  ENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKD 201
            EN  +L L   + K DVP+EQ  Q  G++ T  L+    E I  S+  +D++   ++ +D
Sbjct: 1083 ENEDNLILDIKLKKKDVPLEQGPQIEGSVPTKKLK---SENIALSLLFNDRIHPKDKNED 1139

Query: 202  KN-VNID 207
             + VNID
Sbjct: 1140 SSYVNID 1146


>UniRef50_Q22MU0 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 3499

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 30/128 (23%), Positives = 59/128 (46%), Gaps = 11/128 (8%)

Query: 124  SWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKI 183
            +++++ N+ K  ++ Q  +N +  + S   L     + Q+ +   N +T P   D     
Sbjct: 1894 TYQYIINVIKFKKKFQSNKNQQSSQNSNEYLGSPRDMIQKKERTKNQQTFPTDDD----- 1948

Query: 184  LESVDVSDKVSASEEGKDK-NVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENS 242
                D  D+ +   E KDK   N +++S+ NE+E+   +   YQP       +   S ++
Sbjct: 1949 ----DDLDEEALEAELKDKIEQNFNINSETNELELMDDQSYSYQPLQHQKLFINPQSNSN 2004

Query: 243  LWKWPSNK 250
            L K P+N+
Sbjct: 2005 L-KTPANQ 2011


>UniRef50_A5K441 Cluster: Putative uncharacterized protein; n=2;
            Plasmodium|Rep: Putative uncharacterized protein -
            Plasmodium vivax
          Length = 5540

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 9/105 (8%)

Query: 134  DNEEKQDAENGK--DLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSD 191
            D +++ DAE  +  D  +   I + +   E++ ++ G  K +  R DAKEK+ E  D  +
Sbjct: 2014 DEDKENDAEINRLMDEGMRRMIEQKEKEQEEKAENGGEEKDAKER-DAKEKVDEEKDAKE 2072

Query: 192  KVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVE 236
            + +  E+ K+       D + NE E  + +EN  +  A+D  D E
Sbjct: 2073 EDAKEEDAKES------DDEENEEEEYADDENEEEEYADDEKDDE 2111


>UniRef50_Q6BIV5 Cluster: Similar to sp|P38759 Saccharomyces
           cerevisiae PEP11 protein; n=1; Debaryomyces
           hansenii|Rep: Similar to sp|P38759 Saccharomyces
           cerevisiae PEP11 protein - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 320

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 3/121 (2%)

Query: 124 SWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKI 183
           ++ W     +  EE+++ E+ KD K        +   E+      + K      D K++I
Sbjct: 163 NFDWPEKEDESEEEEEEGESQKDSKEGNSEPAKEESKEKEIAEEESKKDEENNADKKDEI 222

Query: 184 LESVDVSDKVSASEEGKDKNVNIDMDSKPNE--MEIASPEENLYQPTAEDNTDVEDGSEN 241
            ES +  +K  A EE K+ +   ++DSK NE  +E    +E+     ++D   +E+  E+
Sbjct: 223 -ESNEQENKEGAHEEVKEPSEQKNVDSKDNEGVVEKNKNKEDANDSDSDDTNLIEEVKES 281

Query: 242 S 242
           +
Sbjct: 282 T 282


>UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep:
           Myosin-1 - Pichia stipitis (Yeast)
          Length = 1874

 Score = 36.3 bits (80), Expect = 1.7
 Identities = 22/121 (18%), Positives = 58/121 (47%), Gaps = 7/121 (5%)

Query: 129 SNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIK------TSPLRQDAKEK 182
           +N+ KD + K +    ++ K+S+ I + +  I Q  Q N  +        S L++ ++  
Sbjct: 876 TNLVKDKDLKLEKAKSEEAKISSRIREFESKINQMKQENNKLSEEKKLLDSKLKESSENS 935

Query: 183 ILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENS 242
                D+S      ++ K K  ++++  K +++E    E+++ +   +++  ++  SE+ 
Sbjct: 936 NRNIADLSSLTKERDDFKSKLADLELVVKKHKLEKVEREKHI-EDLKKEHASLKSSSESK 994

Query: 243 L 243
           +
Sbjct: 995 V 995


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.322    0.138    0.435 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 486,417,782
Number of Sequences: 1657284
Number of extensions: 20275237
Number of successful extensions: 60508
Number of sequences better than 10.0: 381
Number of HSP's better than 10.0 without gapping: 229
Number of HSP's successfully gapped in prelim test: 152
Number of HSP's that attempted gapping in prelim test: 59392
Number of HSP's gapped (non-prelim): 1173
length of query: 459
length of database: 575,637,011
effective HSP length: 103
effective length of query: 356
effective length of database: 404,936,759
effective search space: 144157486204
effective search space used: 144157486204
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 74 (33.9 bits)

- SilkBase 1999-2023 -