Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000538-TA|BGIBMGA000538-PA|IPR004481|K+-dependent
Na+/Ca+ exchanger related-protein, IPR004836|Sodium/calcium exchanger
protein, IPR004837|Sodium/calcium exchanger membrane region
(459 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF520705-1|AAM76071.1| 586|Homo sapiens K-dependent Na/Ca excha... 277 5e-74
AL158206-3|CAH73021.1| 644|Homo sapiens solute carrier family 2... 191 5e-48
AL158077-1|CAH74109.1| 644|Homo sapiens solute carrier family 2... 191 5e-48
AL133281-1|CAH71737.1| 644|Homo sapiens solute carrier family 2... 191 5e-48
AF177987-1|AAF25811.1| 644|Homo sapiens cone sodium-calcium pot... 191 5e-48
AL139429-1|CAC13155.2| 644|Homo sapiens solute carrier family 2... 176 1e-43
AL136090-1|CAI17163.1| 644|Homo sapiens solute carrier family 2... 176 1e-43
AL121830-1|CAC36052.2| 644|Homo sapiens solute carrier family 2... 176 1e-43
AL121761-1|CAC12640.2| 644|Homo sapiens solute carrier family 2... 176 1e-43
AL049647-1|CAC36050.2| 644|Homo sapiens solute carrier family 2... 176 1e-43
AL034425-1|CAC36051.2| 644|Homo sapiens solute carrier family 2... 176 1e-43
AF169257-1|AAG12988.2| 625|Homo sapiens potassium-dependent Na/... 176 1e-43
BC069653-1|AAH69653.1| 605|Homo sapiens solute carrier family 2... 168 4e-41
AL834225-1|CAD38903.1| 316|Homo sapiens hypothetical protein pr... 168 4e-41
AF520706-1|AAM76072.1| 558|Homo sapiens K-dependent Na/Ca excha... 168 4e-41
AF520704-1|AAM76070.1| 605|Homo sapiens K-dependent Na/Ca excha... 168 4e-41
BC113630-1|AAI13631.1| 500|Homo sapiens solute carrier family 2... 151 5e-36
BC113628-1|AAI13629.1| 500|Homo sapiens solute carrier family 2... 151 5e-36
BC073944-1|AAH73944.1| 218|Homo sapiens SLC24A5 protein protein. 151 5e-36
AF348468-1|AAQ15116.1| 500|Homo sapiens ion transporter JSX pro... 151 5e-36
BC069622-1|AAH69622.1| 661|Homo sapiens solute carrier family 2... 118 4e-26
AL158206-2|CAH73020.1| 661|Homo sapiens solute carrier family 2... 118 4e-26
AL158077-2|CAH74108.1| 661|Homo sapiens solute carrier family 2... 118 4e-26
AL133281-2|CAH71736.1| 661|Homo sapiens solute carrier family 2... 118 4e-26
AF097366-1|AAF21810.1| 661|Homo sapiens cone sodium-calcium pot... 118 4e-26
AF062922-1|AAC77912.1| 1099|Homo sapiens retinal rod Na-Ca+K exc... 114 5e-25
AF062921-1|AAC16732.1| 1099|Homo sapiens retinal rod Na-Ca+K exc... 114 5e-25
AF026132-1|AAB97832.1| 1081|Homo sapiens retinal rod Na+/Ca+, K+... 114 5e-25
BC117263-1|AAI17264.1| 1069|Homo sapiens SLC24A1 protein protein. 109 2e-23
AB014602-1|BAA31677.2| 988|Homo sapiens KIAA0702 protein protein. 102 3e-21
AK096171-1|BAC04715.1| 352|Homo sapiens protein ( Homo sapiens ... 54 1e-06
BC098360-1|AAH98360.1| 584|Homo sapiens SLC24A6 protein protein. 53 2e-06
AY601760-1|AAT35808.1| 528|Homo sapiens Na+/Ca2+ K+ independent... 53 2e-06
AY601759-1|AAT35807.1| 584|Homo sapiens Na+/Ca2+ K+ independent... 53 2e-06
AK025886-1|BAB15271.1| 389|Homo sapiens protein ( Homo sapiens ... 53 2e-06
M91368-1|AAA35702.1| 973|Homo sapiens Na+/Ca+ exchanger protein. 50 2e-05
BC098308-1|AAH98308.1| 335|Homo sapiens SLC8A1 protein protein. 50 2e-05
BC098285-1|AAH98285.1| 384|Homo sapiens SLC8A1 protein protein. 50 2e-05
AF128524-1|AAD26362.1| 960|Homo sapiens sodium-calcium exchange... 50 2e-05
AF108389-1|AAF08988.1| 937|Homo sapiens sodium/calcium exchange... 50 2e-05
AF108388-1|AAF08987.1| 960|Homo sapiens sodium/calcium exchange... 50 2e-05
AB209075-1|BAD92312.1| 411|Homo sapiens solute carrier family 8... 50 2e-05
AJ745102-1|CAG33740.1| 298|Homo sapiens Na+/Ca2+ exchanger 3 pr... 44 9e-04
AJ745101-1|CAG33739.1| 284|Homo sapiens Na+/Ca2+ exchanger 3 pr... 44 9e-04
AJ508602-1|CAD48420.1| 771|Homo sapiens Na+/Ca2+ exchanger isof... 44 9e-04
AJ304853-1|CAC40985.1| 924|Homo sapiens sodium/calcium exchange... 44 9e-04
AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchange... 44 9e-04
AF510502-1|AAN60791.1| 927|Homo sapiens Na+/Ca2+ exchanger isof... 44 9e-04
AF510501-1|AAN60790.1| 921|Homo sapiens Na+/Ca2+ exchanger isof... 44 9e-04
AF508982-1|AAM90955.1| 927|Homo sapiens Na+/Ca2+ exchanger isof... 44 9e-04
AB029010-1|BAA83039.1| 952|Homo sapiens KIAA1087 protein protein. 42 0.003
AC007377-1|AAX81985.1| 245|Homo sapiens unknown protein. 40 0.014
AC007281-1|AAF19237.1| 603|Homo sapiens unknown protein. 38 0.056
AF461266-1|AAL67520.1| 606|Homo sapiens RUFY2 protein. 37 0.13
AF411980-1|AAL04164.1| 590|Homo sapiens Run- and FYVE-domain co... 37 0.13
AB040970-1|BAA96061.1| 619|Homo sapiens KIAA1537 protein protein. 37 0.13
BC114217-1|AAI14218.1| 210|Homo sapiens SLC8A3 protein protein. 36 0.23
AF177377-1|AAG09279.2| 981|Homo sapiens cytoplasmic protein pro... 35 0.69
AC006038-1|AAY15086.1| 911|Homo sapiens unknown protein. 35 0.69
BC093405-1|AAH93405.1| 550|Homo sapiens PHF20 protein protein. 34 0.91
BC080598-1|AAH80598.1| 550|Homo sapiens PHF20 protein protein. 34 0.91
BC048210-1|AAH48210.1| 549|Homo sapiens PHF20 protein protein. 34 0.91
AY134747-1|AAN08621.1| 550|Homo sapiens medulloblastoma antigen... 34 0.91
AY027523-1|AAK13046.1| 1012|Homo sapiens transcription factor TZ... 34 0.91
AL109965-3|CAI19247.1| 1012|Homo sapiens PHD finger protein 20 p... 34 0.91
AL109965-2|CAM27594.1| 549|Homo sapiens PHD finger protein 20 p... 34 0.91
AL109965-1|CAI19246.1| 543|Homo sapiens PHD finger protein 20 p... 34 0.91
AL078461-5|CAI43148.1| 256|Homo sapiens PHD finger protein 20 p... 34 0.91
AL078461-3|CAI43145.1| 1012|Homo sapiens PHD finger protein 20 p... 34 0.91
AL078461-2|CAI43146.2| 549|Homo sapiens PHD finger protein 20 p... 34 0.91
AL078461-1|CAI43144.1| 543|Homo sapiens PHD finger protein 20 p... 34 0.91
AF348207-1|AAK19748.1| 639|Homo sapiens C2H2 zinc finger protei... 34 0.91
M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase p... 33 2.1
AL512764-1|CAC21681.1| 793|Homo sapiens hypothetical protein pr... 33 2.1
AF510503-1|AAN60792.1| 620|Homo sapiens Na+/Ca2+ exchanger isof... 33 2.1
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 32 4.9
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 32 4.9
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 32 4.9
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 32 4.9
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 32 4.9
X98332-1|CAA66977.1| 554|Homo sapiens organic cation transporte... 31 6.4
U77086-1|AAB67703.1| 554|Homo sapiens organic cation transporte... 31 6.4
CR456730-1|CAG33011.1| 422|Homo sapiens NOL4 protein. 31 6.4
BT006763-1|AAP35409.1| 422|Homo sapiens nucleolar protein 4 pro... 31 6.4
BC126364-1|AAI26365.1| 554|Homo sapiens solute carrier family 2... 31 6.4
BC041092-1|AAH41092.1| 403|Homo sapiens RUN and FYVE domain con... 31 6.4
BC000313-1|AAH00313.1| 422|Homo sapiens NOL4 protein protein. 31 6.4
AL353625-3|CAH72016.1| 554|Homo sapiens solute carrier family 2... 31 6.4
AJ243995-1|CAB95971.1| 554|Homo sapiens protein ( Homo sapiens ... 31 6.4
AB017800-1|BAA34576.1| 524|Homo sapiens nolp protein. 31 6.4
Z84487-2|CAI42675.1| 2454|Homo sapiens alpha thalassemia/mental ... 31 8.5
Z84487-1|CAI42674.1| 2492|Homo sapiens alpha thalassemia/mental ... 31 8.5
U97103-1|AAC51657.1| 2375|Homo sapiens X-linked nuclear protein ... 31 8.5
U75653-1|AAC51655.1| 2492|Homo sapiens zinc finger helicase prot... 31 8.5
U72938-1|AAB49971.2| 2454|Homo sapiens putative DNA dependent AT... 31 8.5
U72937-1|AAB49970.2| 2492|Homo sapiens putative DNA dependent AT... 31 8.5
U72936-1|AAB49969.1| 2288|Homo sapiens putative DNA dependent AT... 31 8.5
U72935-3|AAB40700.1| 2288|Homo sapiens putative DNA dependent AT... 31 8.5
U72935-2|AAB40699.1| 2337|Homo sapiens putative DNA dependent AT... 31 8.5
U72935-1|AAB40698.1| 2375|Homo sapiens putative DNA dependent AT... 31 8.5
U09820-1|AAC50069.1| 1641|Homo sapiens helicase II protein. 31 8.5
L34363-1|AAA20872.1| 1298|Homo sapiens X-linked nuclear protein ... 31 8.5
EF467914-1|ABO43036.1| 2492|Homo sapiens alpha thalassemia/menta... 31 8.5
AL354890-2|CAI21914.1| 810|Homo sapiens ecotropic viral integra... 31 8.5
AL133332-1|CAC19437.2| 810|Homo sapiens ecotropic viral integra... 31 8.5
AL121874-2|CAB90351.2| 2454|Homo sapiens alpha thalassemia/menta... 31 8.5
AL121874-1|CAI40710.1| 2492|Homo sapiens alpha thalassemia/menta... 31 8.5
AL109753-2|CAI43115.1| 2492|Homo sapiens alpha thalassemia/menta... 31 8.5
AL109753-1|CAI43116.1| 2454|Homo sapiens alpha thalassemia/menta... 31 8.5
AK125340-1|BAC86137.1| 292|Homo sapiens protein ( Homo sapiens ... 31 8.5
AF042345-1|AAC16041.1| 607|Homo sapiens truncated EVI5 protein. 31 8.5
AF008915-1|AAC16031.1| 810|Homo sapiens EVI-5 homolog protein. 31 8.5
AB209545-1|BAD92782.1| 1224|Homo sapiens transcriptional regulat... 31 8.5
AB208928-1|BAD92165.1| 1383|Homo sapiens transcriptional regulat... 31 8.5
AB102641-1|BAC81110.1| 2492|Homo sapiens ATRX protein. 31 8.5
>AF520705-1|AAM76071.1| 586|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 586
Score = 277 bits (680), Expect = 5e-74
Identities = 170/473 (35%), Positives = 247/473 (52%), Gaps = 21/473 (4%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 118 LSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 177
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L WW + RD + Y I+V +LI I+DE + W+E +L+ LY YI IM Y+ +Q F
Sbjct: 178 VVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAF 237
Query: 121 AKGSWKWVSNMFKDNEE----KQDAENGKDLKLSTHILKIDVPIEQRHQHNG-----NIK 171
K ++N N E K+ + GK+ + + P + G K
Sbjct: 238 FTVKQKSIANGNPVNSELEAVKEKPQYGKNPVVMVDEIMSSSPPKFTFPEAGLRIMITNK 297
Query: 172 TSP---LRQDAKEKILES---VDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLY 225
P LR ++ I E ++ ++ VS+ ++ NI+ + P E P++N
Sbjct: 298 FGPRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHENIENGNVPVENP-EDPQQNQE 356
Query: 226 Q--PTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNW 283
Q P + E + L + ++ K+ + TWP+ + TIP+C KPR++ +
Sbjct: 357 QQPPPQPPPPEPEPVEADFLSPFSVPEARGDKVKWVFTWPLIFLLCVTIPNCSKPRWEKF 416
Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
F +TFI +WI SYI+ W++TIIG TL IPD +MGITFLAAGTSVP+ ++S+IVA+Q
Sbjct: 417 FMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQ 476
Query: 344 XXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXX 403
FDIL+ LG+PW ++ + VKINS GL YS +
Sbjct: 477 GLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGS---TVKINSRGLVYSVVLLLGSV 533
Query: 404 XXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVFFPVNVRTCKRAD 456
NK++LD +G L +YA+FL + +IE NVF VN+ C+ D
Sbjct: 534 ALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEFNVFTFVNLPMCREDD 586
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 112 ICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
>AL158206-3|CAH73021.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 191 bits (465), Expect = 5e-48
Identities = 131/488 (26%), Positives = 228/488 (46%), Gaps = 52/488 (10%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKID--VPIEQRHQHNGN---IKTSPL 175
KWV M N+ + K S K + +P + R Q G+ + S +
Sbjct: 288 -----KWVKQMINRNKVVKVTAPEAQAKPSAARDKDEPTLPAKPRLQRGGSSASLHNSLM 342
Query: 176 RQDAKEKILESVD------VSDKVSASEEGKDKNVNIDMDSKPN-------EMEIAS--- 219
R + ++ ++D +K S + K ++D + + N ++E+ +
Sbjct: 343 RNSIFQLMIHTLDPLAEGRFREKASILHKIAKKKCHVDENERQNGAANHVEKIELPNSTS 402
Query: 220 ------PEENLYQPT-----------AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTW 262
P + +P AE T E+ + WPS ++T ++ +
Sbjct: 403 TDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSLAWPSETR--KQVTFLIVF 460
Query: 263 PIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGI 322
PI T+PD KP + +FP+TF I WI SY++ W +G+T+ I + +MG+
Sbjct: 461 PIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGL 520
Query: 323 TFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGH 382
T LAAGTS+P+ ++SVIVA++ FDI + L LPWL+ + +P
Sbjct: 521 TILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP-- 578
Query: 383 YWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELN 442
V ++S GL + + K++++ +G +Y +FL+++ L+E
Sbjct: 579 --VAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDR 636
Query: 443 VF-FPVNV 449
+ PV++
Sbjct: 637 ILTCPVSI 644
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AL158077-1|CAH74109.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 191 bits (465), Expect = 5e-48
Identities = 131/488 (26%), Positives = 228/488 (46%), Gaps = 52/488 (10%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKID--VPIEQRHQHNGN---IKTSPL 175
KWV M N+ + K S K + +P + R Q G+ + S +
Sbjct: 288 -----KWVKQMINRNKVVKVTAPEAQAKPSAARDKDEPTLPAKPRLQRGGSSASLHNSLM 342
Query: 176 RQDAKEKILESVD------VSDKVSASEEGKDKNVNIDMDSKPN-------EMEIAS--- 219
R + ++ ++D +K S + K ++D + + N ++E+ +
Sbjct: 343 RNSIFQLMIHTLDPLAEGRFREKASILHKIAKKKCHVDENERQNGAANHVEKIELPNSTS 402
Query: 220 ------PEENLYQPT-----------AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTW 262
P + +P AE T E+ + WPS ++T ++ +
Sbjct: 403 TDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSLAWPSETR--KQVTFLIVF 460
Query: 263 PIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGI 322
PI T+PD KP + +FP+TF I WI SY++ W +G+T+ I + +MG+
Sbjct: 461 PIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGL 520
Query: 323 TFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGH 382
T LAAGTS+P+ ++SVIVA++ FDI + L LPWL+ + +P
Sbjct: 521 TILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP-- 578
Query: 383 YWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELN 442
V ++S GL + + K++++ +G +Y +FL+++ L+E
Sbjct: 579 --VAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDR 636
Query: 443 VF-FPVNV 449
+ PV++
Sbjct: 637 ILTCPVSI 644
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AL133281-1|CAH71737.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 191 bits (465), Expect = 5e-48
Identities = 131/488 (26%), Positives = 228/488 (46%), Gaps = 52/488 (10%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKID--VPIEQRHQHNGN---IKTSPL 175
KWV M N+ + K S K + +P + R Q G+ + S +
Sbjct: 288 -----KWVKQMINRNKVVKVTAPEAQAKPSAARDKDEPTLPAKPRLQRGGSSASLHNSLM 342
Query: 176 RQDAKEKILESVD------VSDKVSASEEGKDKNVNIDMDSKPN-------EMEIAS--- 219
R + ++ ++D +K S + K ++D + + N ++E+ +
Sbjct: 343 RNSIFQLMIHTLDPLAEGRFREKASILHKIAKKKCHVDENERQNGAANHVEKIELPNSTS 402
Query: 220 ------PEENLYQPT-----------AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTW 262
P + +P AE T E+ + WPS ++T ++ +
Sbjct: 403 TDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSLAWPSETR--KQVTFLIVF 460
Query: 263 PIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGI 322
PI T+PD KP + +FP+TF I WI SY++ W +G+T+ I + +MG+
Sbjct: 461 PIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGL 520
Query: 323 TFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGH 382
T LAAGTS+P+ ++SVIVA++ FDI + L LPWL+ + +P
Sbjct: 521 TILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP-- 578
Query: 383 YWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELN 442
V ++S GL + + K++++ +G +Y +FL+++ L+E
Sbjct: 579 --VAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDR 636
Query: 443 VF-FPVNV 449
+ PV++
Sbjct: 637 ILTCPVSI 644
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AF177987-1|AAF25811.1| 644|Homo sapiens cone sodium-calcium
potassium exchanger splice variant protein.
Length = 644
Score = 191 bits (465), Expect = 5e-48
Identities = 131/488 (26%), Positives = 228/488 (46%), Gaps = 52/488 (10%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKID--VPIEQRHQHNGN---IKTSPL 175
KWV M N+ + K S K + +P + R Q G+ + S +
Sbjct: 288 -----KWVKQMINRNKVVKVTAPEAQAKPSAARDKDEPTLPAKPRLQRGGSSASLHNSLM 342
Query: 176 RQDAKEKILESVD------VSDKVSASEEGKDKNVNIDMDSKPN-------EMEIAS--- 219
R + ++ ++D +K S + K ++D + + N ++E+ +
Sbjct: 343 RNSIFQLMIHTLDPLAEGRFREKASILHKIAKKKCHVDENERQNGAANHVEKIELPNSTS 402
Query: 220 ------PEENLYQPT-----------AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTW 262
P + +P AE T E+ + WPS ++T ++ +
Sbjct: 403 TDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSLAWPSETR--KQVTFLIVF 460
Query: 263 PIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGI 322
PI T+PD KP + +FP+TF I WI SY++ W +G+T+ I + +MG+
Sbjct: 461 PIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGL 520
Query: 323 TFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGH 382
T LAAGTS+P+ ++SVIVA++ FDI + L LPWL+ + +P
Sbjct: 521 TILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP-- 578
Query: 383 YWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELN 442
V ++S GL + + K++++ +G +Y +FL+++ L+E
Sbjct: 579 --VAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDR 636
Query: 443 VF-FPVNV 449
+ PV++
Sbjct: 637 ILTCPVSI 644
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AL139429-1|CAC13155.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 176 bits (429), Expect = 1e-43
Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)
Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
D+ VN D E + EN E+ + ED E + + L +
Sbjct: 392 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 451
Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
TWP+ V FT+P+C KPR++ WF +TF +WI + SY++ WM+TIIG TL IPD +
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511
Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LGLPW ++ +
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 569
Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
G Y +++NS GL YS NK++LD +G CL +Y +FL + +
Sbjct: 570 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 628
Query: 440 ELNVFFPVNVRTC 452
E NVF VN+ C
Sbjct: 629 EFNVFTFVNLPMC 641
Score = 126 bits (303), Expect = 2e-28
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ I
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 264
Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
+ K NM +N E D+ N
Sbjct: 265 FERRTKGAGNMVNGLANNAEIDDSSN 290
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 139 ICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
>AL136090-1|CAI17163.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 176 bits (429), Expect = 1e-43
Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)
Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
D+ VN D E + EN E+ + ED E + + L +
Sbjct: 392 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 451
Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
TWP+ V FT+P+C KPR++ WF +TF +WI + SY++ WM+TIIG TL IPD +
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511
Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LGLPW ++ +
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 569
Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
G Y +++NS GL YS NK++LD +G CL +Y +FL + +
Sbjct: 570 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 628
Query: 440 ELNVFFPVNVRTC 452
E NVF VN+ C
Sbjct: 629 EFNVFTFVNLPMC 641
Score = 126 bits (303), Expect = 2e-28
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ I
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 264
Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
+ K NM +N E D+ N
Sbjct: 265 FERRTKGAGNMVNGLANNAEIDDSSN 290
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 139 ICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
>AL121830-1|CAC36052.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 176 bits (429), Expect = 1e-43
Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)
Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
D+ VN D E + EN E+ + ED E + + L +
Sbjct: 392 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 451
Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
TWP+ V FT+P+C KPR++ WF +TF +WI + SY++ WM+TIIG TL IPD +
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511
Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LGLPW ++ +
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 569
Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
G Y +++NS GL YS NK++LD +G CL +Y +FL + +
Sbjct: 570 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 628
Query: 440 ELNVFFPVNVRTC 452
E NVF VN+ C
Sbjct: 629 EFNVFTFVNLPMC 641
Score = 126 bits (303), Expect = 2e-28
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ I
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 264
Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
+ K NM +N E D+ N
Sbjct: 265 FERRTKGAGNMVNGLANNAEIDDSSN 290
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 139 ICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
>AL121761-1|CAC12640.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 176 bits (429), Expect = 1e-43
Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)
Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
D+ VN D E + EN E+ + ED E + + L +
Sbjct: 392 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 451
Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
TWP+ V FT+P+C KPR++ WF +TF +WI + SY++ WM+TIIG TL IPD +
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511
Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LGLPW ++ +
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 569
Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
G Y +++NS GL YS NK++LD +G CL +Y +FL + +
Sbjct: 570 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 628
Query: 440 ELNVFFPVNVRTC 452
E NVF VN+ C
Sbjct: 629 EFNVFTFVNLPMC 641
Score = 126 bits (303), Expect = 2e-28
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ I
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 264
Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
+ K NM +N E D+ N
Sbjct: 265 FERRTKGAGNMVNGLANNAEIDDSSN 290
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 139 ICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
>AL049647-1|CAC36050.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 176 bits (429), Expect = 1e-43
Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)
Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
D+ VN D E + EN E+ + ED E + + L +
Sbjct: 392 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 451
Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
TWP+ V FT+P+C KPR++ WF +TF +WI + SY++ WM+TIIG TL IPD +
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511
Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LGLPW ++ +
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 569
Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
G Y +++NS GL YS NK++LD +G CL +Y +FL + +
Sbjct: 570 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 628
Query: 440 ELNVFFPVNVRTC 452
E NVF VN+ C
Sbjct: 629 EFNVFTFVNLPMC 641
Score = 126 bits (303), Expect = 2e-28
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ I
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 264
Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
+ K NM +N E D+ N
Sbjct: 265 FERRTKGAGNMVNGLANNAEIDDSSN 290
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 139 ICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
>AL034425-1|CAC36051.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 176 bits (429), Expect = 1e-43
Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)
Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
D+ VN D E + EN E+ + ED E + + L +
Sbjct: 392 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 451
Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
TWP+ V FT+P+C KPR++ WF +TF +WI + SY++ WM+TIIG TL IPD +
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511
Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LGLPW ++ +
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 569
Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
G Y +++NS GL YS NK++LD +G CL +Y +FL + +
Sbjct: 570 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 628
Query: 440 ELNVFFPVNVRTC 452
E NVF VN+ C
Sbjct: 629 EFNVFTFVNLPMC 641
Score = 126 bits (303), Expect = 2e-28
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ I
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 264
Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
+ K NM +N E D+ N
Sbjct: 265 FERRTKGAGNMVNGLANNAEIDDSSN 290
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 139 ICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
>AF169257-1|AAG12988.2| 625|Homo sapiens potassium-dependent Na/Ca
exchanger NCKX3 protein.
Length = 625
Score = 176 bits (429), Expect = 1e-43
Identities = 94/253 (37%), Positives = 133/253 (52%), Gaps = 4/253 (1%)
Query: 201 DKNVN-IDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKI 259
D+ VN D E + EN E+ + ED E + + L +
Sbjct: 373 DRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWA 432
Query: 260 VTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSV 319
TWP+ V FT+P+C KPR++ WF +TF +WI + SY++ WM+TIIG TL IPD +
Sbjct: 433 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 492
Query: 320 MGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAE 379
MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LGLPW ++ +
Sbjct: 493 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT--LAVD 550
Query: 380 PGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLI 439
G Y +++NS GL YS NK++LD +G CL +Y +FL + +
Sbjct: 551 YGSY-IRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMT 609
Query: 440 ELNVFFPVNVRTC 452
E NVF VN+ C
Sbjct: 610 EFNVFTFVNLPMC 622
Score = 126 bits (303), Expect = 2e-28
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 126 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 185
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ I
Sbjct: 186 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 245
Query: 121 AKGSWKWVSNM---FKDNEEKQDAEN 143
+ K NM +N E D+ N
Sbjct: 246 FERRTKGAGNMVNGLANNAEIDDSSN 271
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 120 ICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 178
>BC069653-1|AAH69653.1| 605|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 4 protein.
Length = 605
Score = 168 bits (408), Expect = 4e-41
Identities = 84/202 (41%), Positives = 118/202 (58%), Gaps = 3/202 (1%)
Query: 255 KITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLM 314
K+ + TWP+ + TIP+C KPR++ +F +TFI +WI SYI+ W++TIIG TL
Sbjct: 407 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 466
Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
IPD +MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LG+PW ++
Sbjct: 467 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 526
Query: 375 LTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLI 434
+ VKINS GL YS + NK++LD +G L +YA+FL
Sbjct: 527 VVNYGS---TVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLC 583
Query: 435 LATLIELNVFFPVNVRTCKRAD 456
+ +IE NVF VN+ C+ D
Sbjct: 584 FSIMIEFNVFTFVNLPMCREDD 605
Score = 131 bits (316), Expect = 6e-30
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 118 LSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 177
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L WW + RD + Y I+V +LI I+DE + W+E +L+ LY YI IM Y+ +Q F
Sbjct: 178 VVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAF 237
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKD 146
K ++N N + E G D
Sbjct: 238 FTVKQKSIAN---GNPVNSELEAGND 260
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 112 ICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
>AL834225-1|CAD38903.1| 316|Homo sapiens hypothetical protein
protein.
Length = 316
Score = 168 bits (408), Expect = 4e-41
Identities = 84/202 (41%), Positives = 118/202 (58%), Gaps = 3/202 (1%)
Query: 255 KITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLM 314
K+ + TWP+ + TIP+C KPR++ +F +TFI +WI SYI+ W++TIIG TL
Sbjct: 118 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 177
Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
IPD +MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LG+PW ++
Sbjct: 178 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 237
Query: 375 LTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLI 434
+ VKINS GL YS + NK++LD +G L +YA+FL
Sbjct: 238 VVNYGS---TVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLC 294
Query: 435 LATLIELNVFFPVNVRTCKRAD 456
+ +IE NVF VN+ C+ D
Sbjct: 295 FSIMIEFNVFTFVNLPMCREDD 316
>AF520706-1|AAM76072.1| 558|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 558
Score = 168 bits (408), Expect = 4e-41
Identities = 84/202 (41%), Positives = 118/202 (58%), Gaps = 3/202 (1%)
Query: 255 KITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLM 314
K+ + TWP+ + TIP+C KPR++ +F +TFI +WI SYI+ W++TIIG TL
Sbjct: 360 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 419
Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
IPD +MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LG+PW ++
Sbjct: 420 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 479
Query: 375 LTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLI 434
+ VKINS GL YS + NK++LD +G L +YA+FL
Sbjct: 480 VVNYGS---TVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLC 536
Query: 435 LATLIELNVFFPVNVRTCKRAD 456
+ +IE NVF VN+ C+ D
Sbjct: 537 FSIMIEFNVFTFVNLPMCREDD 558
Score = 131 bits (316), Expect = 6e-30
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 71 LSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 130
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L WW + RD + Y I+V +LI I+DE + W+E +L+ LY YI IM Y+ +Q F
Sbjct: 131 VVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAF 190
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKD 146
K ++N N + E G D
Sbjct: 191 FTVKQKSIAN---GNPVNSELEAGND 213
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 65 ICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 123
>AF520704-1|AAM76070.1| 605|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 605
Score = 168 bits (408), Expect = 4e-41
Identities = 84/202 (41%), Positives = 118/202 (58%), Gaps = 3/202 (1%)
Query: 255 KITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLM 314
K+ + TWP+ + TIP+C KPR++ +F +TFI +WI SYI+ W++TIIG TL
Sbjct: 407 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 466
Query: 315 IPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKAS 374
IPD +MGITFLAAGTSVP+ ++S+IVA+Q FDIL+ LG+PW ++
Sbjct: 467 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 526
Query: 375 LTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLI 434
+ VKINS GL YS + NK++LD +G L +YA+FL
Sbjct: 527 VVNYGS---TVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLC 583
Query: 435 LATLIELNVFFPVNVRTCKRAD 456
+ +IE NVF VN+ C+ D
Sbjct: 584 FSIMIEFNVFTFVNLPMCREDD 605
Score = 131 bits (316), Expect = 6e-30
Identities = 65/146 (44%), Positives = 85/146 (58%), Gaps = 3/146 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF +VIG FIT GD+GVGTIVGSAVFNIL + CG+ AG
Sbjct: 118 LSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 177
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
VV L WW + RD + Y I+V +LI I+DE + W+E +L+ LY YI IM Y+ +Q F
Sbjct: 178 VVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAF 237
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKD 146
K ++N N + E G D
Sbjct: 238 FTVKQKSIAN---GNPVNSELEAGND 260
Score = 33.5 bits (73), Expect = 1.6
Identities = 19/59 (32%), Positives = 28/59 (47%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGL 367
I + L + + V G TF+AAG+S PE +SVI F+IL +G+
Sbjct: 112 ICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
>BC113630-1|AAI13631.1| 500|Homo sapiens solute carrier family 24,
member 5 protein.
Length = 500
Score = 151 bits (366), Expect = 5e-36
Identities = 76/200 (38%), Positives = 109/200 (54%), Gaps = 4/200 (2%)
Query: 253 LAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDT 312
L +I +++ PI + T PDC K +KN+F +TF M +WI + +YI+ WM+TI G+T
Sbjct: 303 LKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGET 362
Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
L IPD+VMG+T LAAGTS+P+ ++SV+VA++ FD +LCLG+PW IK
Sbjct: 363 LEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFD-MLCLGIPWFIK 421
Query: 373 ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMF 432
+ G ++NS GL Y I FN +KLD +G CL Y
Sbjct: 422 TAFI---NGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGL 478
Query: 433 LILATLIELNVFFPVNVRTC 452
L+ L EL + +R C
Sbjct: 479 ATLSVLYELGIIGNNKIRGC 498
Score = 114 bits (274), Expect = 7e-25
Identities = 48/120 (40%), Positives = 73/120 (60%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PEL +G FIT+GDIG+ TI+GSA++N+L + A CG+ +
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNT 163
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
V L WPL RDC AY I+ + ++ II+D V WYE LL+ +YG+Y+ ++ +D I +
Sbjct: 164 VSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQY 223
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/34 (41%), Positives = 23/34 (67%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
+ II ++L + V G TF+AAG+S PE V++ +
Sbjct: 95 LEIISESLGLSQDVAGTTFMAAGSSAPELVTAFL 128
>BC113628-1|AAI13629.1| 500|Homo sapiens solute carrier family 24,
member 5 protein.
Length = 500
Score = 151 bits (366), Expect = 5e-36
Identities = 76/200 (38%), Positives = 109/200 (54%), Gaps = 4/200 (2%)
Query: 253 LAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDT 312
L +I +++ PI + T PDC K +KN+F +TF M +WI + +YI+ WM+TI G+T
Sbjct: 303 LKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGET 362
Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
L IPD+VMG+T LAAGTS+P+ ++SV+VA++ FD +LCLG+PW IK
Sbjct: 363 LEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFD-MLCLGIPWFIK 421
Query: 373 ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMF 432
+ G ++NS GL Y I FN +KLD +G CL Y
Sbjct: 422 TAFI---NGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGL 478
Query: 433 LILATLIELNVFFPVNVRTC 452
L+ L EL + +R C
Sbjct: 479 ATLSVLYELGIIGNNKIRGC 498
Score = 114 bits (274), Expect = 7e-25
Identities = 48/120 (40%), Positives = 73/120 (60%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PEL +G FIT+GDIG+ TI+GSA++N+L + A CG+ +
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNT 163
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
V L WPL RDC AY I+ + ++ II+D V WYE LL+ +YG+Y+ ++ +D I +
Sbjct: 164 VSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQY 223
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/34 (41%), Positives = 23/34 (67%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
+ II ++L + V G TF+AAG+S PE V++ +
Sbjct: 95 LEIISESLGLSQDVAGTTFMAAGSSAPELVTAFL 128
>BC073944-1|AAH73944.1| 218|Homo sapiens SLC24A5 protein protein.
Length = 218
Score = 151 bits (366), Expect = 5e-36
Identities = 76/200 (38%), Positives = 109/200 (54%), Gaps = 4/200 (2%)
Query: 253 LAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDT 312
L +I +++ PI + T PDC K +KN+F +TF M +WI + +YI+ WM+TI G+T
Sbjct: 21 LKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGET 80
Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
L IPD+VMG+T LAAGTS+P+ ++SV+VA++ FD +LCLG+PW IK
Sbjct: 81 LEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFD-MLCLGIPWFIK 139
Query: 373 ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMF 432
+ G ++NS GL Y I FN +KLD +G CL Y
Sbjct: 140 TAFI---NGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGL 196
Query: 433 LILATLIELNVFFPVNVRTC 452
L+ L EL + +R C
Sbjct: 197 ATLSVLYELGIIGNNKIRGC 216
>AF348468-1|AAQ15116.1| 500|Homo sapiens ion transporter JSX
protein.
Length = 500
Score = 151 bits (366), Expect = 5e-36
Identities = 76/200 (38%), Positives = 109/200 (54%), Gaps = 4/200 (2%)
Query: 253 LAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDT 312
L +I +++ PI + T PDC K +KN+F +TF M +WI + +YI+ WM+TI G+T
Sbjct: 303 LKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGET 362
Query: 313 LMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIK 372
L IPD+VMG+T LAAGTS+P+ ++SV+VA++ FD +LCLG+PW IK
Sbjct: 363 LEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFD-MLCLGIPWFIK 421
Query: 373 ASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMF 432
+ G ++NS GL Y I FN +KLD +G CL Y
Sbjct: 422 TAFI---NGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGL 478
Query: 433 LILATLIELNVFFPVNVRTC 452
L+ L EL + +R C
Sbjct: 479 ATLSVLYELGIIGNNKIRGC 498
Score = 114 bits (274), Expect = 7e-25
Identities = 48/120 (40%), Positives = 73/120 (60%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PEL +G FIT+GDIG+ TI+GSA++N+L + A CG+ +
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNT 163
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
V L WPL RDC AY I+ + ++ II+D V WYE LL+ +YG+Y+ ++ +D I +
Sbjct: 164 VSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQY 223
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/34 (41%), Positives = 23/34 (67%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
+ II ++L + V G TF+AAG+S PE V++ +
Sbjct: 95 LEIISESLGLSQDVAGTTFMAAGSSAPELVTAFL 128
>BC069622-1|AAH69622.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 118 bits (284), Expect = 4e-26
Identities = 65/222 (29%), Positives = 112/222 (50%), Gaps = 7/222 (3%)
Query: 229 AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTF 288
AE T E+ + WPS ++T ++ +PI T+PD KP + +FP+TF
Sbjct: 446 AEAQTADEEEDQPLSLAWPSETR--KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITF 503
Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
I WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++
Sbjct: 504 FGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDM 563
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXX 408
FDI + L LPWL+ + +P V ++S GL + +
Sbjct: 564 AVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP----VAVSSNGLFCAIVLLFIMLLFVIL 619
Query: 409 XFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FL+++ L+E + PV++
Sbjct: 620 SIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI 661
Score = 101 bits (242), Expect = 5e-21
Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNE 136
KWV M N+
Sbjct: 288 -----KWVKQMINRNK 298
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AL158206-2|CAH73020.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 118 bits (284), Expect = 4e-26
Identities = 65/222 (29%), Positives = 112/222 (50%), Gaps = 7/222 (3%)
Query: 229 AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTF 288
AE T E+ + WPS ++T ++ +PI T+PD KP + +FP+TF
Sbjct: 446 AEAQTADEEEDQPLSLAWPSETR--KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITF 503
Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
I WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++
Sbjct: 504 FGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDM 563
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXX 408
FDI + L LPWL+ + +P V ++S GL + +
Sbjct: 564 AVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP----VAVSSNGLFCAIVLLFIMLLFVIL 619
Query: 409 XFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FL+++ L+E + PV++
Sbjct: 620 SIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI 661
Score = 101 bits (242), Expect = 5e-21
Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNE 136
KWV M N+
Sbjct: 288 -----KWVKQMINRNK 298
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AL158077-2|CAH74108.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 118 bits (284), Expect = 4e-26
Identities = 65/222 (29%), Positives = 112/222 (50%), Gaps = 7/222 (3%)
Query: 229 AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTF 288
AE T E+ + WPS ++T ++ +PI T+PD KP + +FP+TF
Sbjct: 446 AEAQTADEEEDQPLSLAWPSETR--KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITF 503
Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
I WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++
Sbjct: 504 FGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDM 563
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXX 408
FDI + L LPWL+ + +P V ++S GL + +
Sbjct: 564 AVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP----VAVSSNGLFCAIVLLFIMLLFVIL 619
Query: 409 XFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FL+++ L+E + PV++
Sbjct: 620 SIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI 661
Score = 101 bits (242), Expect = 5e-21
Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNE 136
KWV M N+
Sbjct: 288 -----KWVKQMINRNK 298
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AL133281-2|CAH71736.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 118 bits (284), Expect = 4e-26
Identities = 65/222 (29%), Positives = 112/222 (50%), Gaps = 7/222 (3%)
Query: 229 AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTF 288
AE T E+ + WPS ++T ++ +PI T+PD KP + +FP+TF
Sbjct: 446 AEAQTADEEEDQPLSLAWPSETR--KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITF 503
Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
I WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++
Sbjct: 504 FGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDM 563
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXX 408
FDI + L LPWL+ + +P V ++S GL + +
Sbjct: 564 AVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP----VAVSSNGLFCAIVLLFIMLLFVIL 619
Query: 409 XFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FL+++ L+E + PV++
Sbjct: 620 SIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI 661
Score = 101 bits (242), Expect = 5e-21
Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNE 136
KWV M N+
Sbjct: 288 -----KWVKQMINRNK 298
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AF097366-1|AAF21810.1| 661|Homo sapiens cone sodium-calcium
potassium exchanger protein.
Length = 661
Score = 118 bits (284), Expect = 4e-26
Identities = 65/222 (29%), Positives = 112/222 (50%), Gaps = 7/222 (3%)
Query: 229 AEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTF 288
AE T E+ + WPS ++T ++ +PI T+PD KP + +FP+TF
Sbjct: 446 AEAQTADEEEDQPLSLAWPSETR--KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITF 503
Query: 289 IMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXX 348
I WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++
Sbjct: 504 FGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDM 563
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXX 408
FDI + L LPWL+ + +P V ++S GL + +
Sbjct: 564 AVSSSVGSNIFDITVGLPLPWLLYTVIHRFQP----VAVSSNGLFCAIVLLFIMLLFVIL 619
Query: 409 XFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FL+++ L+E + PV++
Sbjct: 620 SIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI 661
Score = 101 bits (242), Expect = 5e-21
Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
+++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + +
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSRE 229
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ ++
Sbjct: 230 ILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVE-- 287
Query: 121 AKGSWKWVSNMFKDNE 136
KWV M N+
Sbjct: 288 -----KWVKQMINRNK 298
Score = 38.7 bits (86), Expect = 0.042
Identities = 21/62 (33%), Positives = 30/62 (48%)
Query: 306 ITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCL 365
+T+I + L I D V G TF+AAG S PE +S+I F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 366 GL 367
G+
Sbjct: 221 GM 222
>AF062922-1|AAC77912.1| 1099|Homo sapiens retinal rod Na-Ca+K
exchanger protein.
Length = 1099
Score = 114 bits (275), Expect = 5e-25
Identities = 74/291 (25%), Positives = 136/291 (46%), Gaps = 11/291 (3%)
Query: 164 HQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEE---GKDKNVNIDMDSKPNEMEIASP 220
H +G +K + +++E E+ + E G D + + + + E E
Sbjct: 815 HAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE 874
Query: 221 EENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPR 279
EE + E+ + E G+E L WP + A ++ PI T+PD +
Sbjct: 875 EEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLL--PIVFPLWLTVPDVRRQE 932
Query: 280 FKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
+ +F TF+ I+WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVI
Sbjct: 933 SRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVI 992
Query: 340 VAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXX 399
VA++ FDI + L +PWL+ + + +P V ++S GL + +
Sbjct: 993 VARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQP----VPVSSNGLFCAIVLL 1048
Query: 400 XXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FLI++ ++E + PV+V
Sbjct: 1049 FLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1099
Score = 109 bits (263), Expect = 2e-23
Identities = 66/226 (29%), Positives = 115/226 (50%), Gaps = 5/226 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + +
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSRE 549
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL+ Y Y+ M ++K I+ +
Sbjct: 550 ILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVW 609
Query: 121 AKG--SWKWVSNM--FKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
K S + V+ + +D + D D LK+ + R + ++ S +R
Sbjct: 610 VKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLP-SLLTRGSSSTSLHNSTIR 668
Query: 177 QDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEE 222
+ +L S+D +V ++E +++++N ++P + PEE
Sbjct: 669 STIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEE 714
Score = 36.7 bits (81), Expect = 0.17
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
F + ++ + I Y V + +I D L I + V G TF+AAG S PE +S+I
Sbjct: 460 FGMMYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518
Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
F+IL +G
Sbjct: 519 SHSNVGIGTIVGSAVFNILFVIG 541
>AF062921-1|AAC16732.1| 1099|Homo sapiens retinal rod Na-Ca+K
exchanger splice variant protein.
Length = 1099
Score = 114 bits (275), Expect = 5e-25
Identities = 74/291 (25%), Positives = 136/291 (46%), Gaps = 11/291 (3%)
Query: 164 HQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEE---GKDKNVNIDMDSKPNEMEIASP 220
H +G +K + +++E E+ + E G D + + + + E E
Sbjct: 815 HAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE 874
Query: 221 EENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPR 279
EE + E+ + E G+E L WP + A ++ PI T+PD +
Sbjct: 875 EEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLL--PIVFPLWLTVPDVRRQE 932
Query: 280 FKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
+ +F TF+ I+WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVI
Sbjct: 933 SRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVI 992
Query: 340 VAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXX 399
VA++ FDI + L +PWL+ + + +P V ++S GL + +
Sbjct: 993 VARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQP----VPVSSNGLFCAIVLL 1048
Query: 400 XXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FLI++ ++E + PV+V
Sbjct: 1049 FLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1099
Score = 109 bits (263), Expect = 2e-23
Identities = 66/226 (29%), Positives = 115/226 (50%), Gaps = 5/226 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + +
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSRE 549
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL+ Y Y+ M ++K I+ +
Sbjct: 550 ILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVW 609
Query: 121 AKG--SWKWVSNM--FKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
K S + V+ + +D + D D LK+ + R + ++ S +R
Sbjct: 610 VKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLP-SLLTRGSSSTSLHNSTIR 668
Query: 177 QDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEE 222
+ +L S+D +V ++E +++++N ++P + PEE
Sbjct: 669 STIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEE 714
Score = 36.7 bits (81), Expect = 0.17
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
F + ++ + I Y V + +I D L I + V G TF+AAG S PE +S+I
Sbjct: 460 FGMMYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518
Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
F+IL +G
Sbjct: 519 SHSNVGIGTIVGSAVFNILFVIG 541
>AF026132-1|AAB97832.1| 1081|Homo sapiens retinal rod Na+/Ca+, K+
exchanger protein.
Length = 1081
Score = 114 bits (275), Expect = 5e-25
Identities = 74/291 (25%), Positives = 136/291 (46%), Gaps = 11/291 (3%)
Query: 164 HQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEE---GKDKNVNIDMDSKPNEMEIASP 220
H +G +K + +++E E+ + E G D + + + + E E
Sbjct: 797 HAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE 856
Query: 221 EENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPR 279
EE + E+ + E G+E L WP + A ++ PI T+PD +
Sbjct: 857 EEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLL--PIVFPLWLTVPDVRRQE 914
Query: 280 FKNWFPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
+ +F TF+ I+WI SY++ W +G+T+ I + +MG+T LAAGTS+P+ ++SVI
Sbjct: 915 SRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVI 974
Query: 340 VAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWVKINSMGLEYSAIXX 399
VA++ FDI + L +PWL+ + + +P V ++S GL + +
Sbjct: 975 VARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQP----VPVSSNGLFCAIVLL 1030
Query: 400 XXXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNVF-FPVNV 449
K++++ +G +Y +FLI++ ++E + PV+V
Sbjct: 1031 FLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1081
Score = 101 bits (243), Expect = 4e-21
Identities = 64/222 (28%), Positives = 110/222 (49%), Gaps = 15/222 (6%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + +
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCSLFSRE 549
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL+ Y Y+ M ++K I+
Sbjct: 550 ILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIE-- 607
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAK 180
WV E+ K + L + K+ + R + ++ S +R
Sbjct: 608 -----VWV------KEQLSRRPVAKVMALE-DLSKLP-SLLTRGSSSTSLHNSTIRSTIY 654
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEE 222
+ +L S+D +V ++E +++++N ++P + PEE
Sbjct: 655 QLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEE 696
Score = 36.3 bits (80), Expect = 0.23
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
F + ++ + I Y V + +I D L I + V G TF+AAG S PE +S+I
Sbjct: 460 FGMMYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGIFI 518
Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
F+IL +G
Sbjct: 519 SHSNVGIGTIVGSAVFNILFVIG 541
>BC117263-1|AAI17264.1| 1069|Homo sapiens SLC24A1 protein protein.
Length = 1069
Score = 109 bits (263), Expect = 2e-23
Identities = 66/226 (29%), Positives = 115/226 (50%), Gaps = 5/226 (2%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + +
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSRE 549
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL+ Y Y+ M ++K I+ +
Sbjct: 550 ILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVW 609
Query: 121 AKG--SWKWVSNM--FKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
K S + V+ + +D + D D LK+ + R + ++ S +R
Sbjct: 610 VKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLP-SLLTRGSSSTSLHNSTIR 668
Query: 177 QDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEE 222
+ +L S+D +V ++E +++++N ++P + PEE
Sbjct: 669 STIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEE 714
Score = 72.1 bits (169), Expect = 4e-12
Identities = 40/142 (28%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLP 368
+G+T+ I + +MG+T LAAGTS+P+ ++SVIVA++ FDI + L +P
Sbjct: 932 VGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVP 991
Query: 369 WLIKASLTPAEPGHYWVKINSMGLEYSAIXXXXXXXXXXXXFWFNKFKLDAAVGRACLAM 428
WL+ + + +P V ++S GL + + K++++ +G +
Sbjct: 992 WLLFSLINGLQP----VPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLL 1047
Query: 429 YAMFLILATLIELNVF-FPVNV 449
Y +FLI++ ++E + PV+V
Sbjct: 1048 YFVFLIISVMLEDRIISCPVSV 1069
Score = 36.7 bits (81), Expect = 0.17
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
F + ++ + I Y V + +I D L I + V G TF+AAG S PE +S+I
Sbjct: 460 FGMMYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518
Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
F+IL +G
Sbjct: 519 SHSNVGIGTIVGSAVFNILFVIG 541
>AB014602-1|BAA31677.2| 988|Homo sapiens KIAA0702 protein protein.
Length = 988
Score = 102 bits (244), Expect = 3e-21
Identities = 64/222 (28%), Positives = 110/222 (49%), Gaps = 15/222 (6%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60
++ DV PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + +
Sbjct: 493 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSRE 552
Query: 61 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 120
++ L WWPL RD Y + + +LI D + W+E+ LL+ Y Y+ M ++K I+
Sbjct: 553 ILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIE-- 610
Query: 121 AKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAK 180
WV E+ K + L + K+ + R + ++ S +R
Sbjct: 611 -----VWV------KEQLSRRPVAKVMALE-DLSKLP-SLLTRGSSSTSLHNSTIRSTIY 657
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEE 222
+ +L S+D +V ++E +++++N ++P + PEE
Sbjct: 658 QLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEE 699
Score = 49.6 bits (113), Expect = 2e-05
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 6/145 (4%)
Query: 164 HQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEE---GKDKNVNIDMDSKPNEMEIASP 220
H +G +K + +++E E+ + E G D + + + + E E
Sbjct: 800 HAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE 859
Query: 221 EENLYQPTAEDNTDVEDGSENSL-WKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPR 279
EE + E+ + E G+E L WP + A ++ PI T+PD +
Sbjct: 860 EEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLL--PIVFPLWLTVPDVRRQE 917
Query: 280 FKNWFPLTFIMCIVWIGSLSYIVAW 304
+ +F TF+ I+WI SY++ W
Sbjct: 918 SRKFFVFTFLGSIMWIAMFSYLMVW 942
Score = 36.7 bits (81), Expect = 0.17
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 284 FPLTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ 343
F + ++ + I Y V + +I D L I + V G TF+AAG S PE +S+I
Sbjct: 463 FGMMYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 521
Query: 344 XXXXXXXXXXXXXXTFDILLCLG 366
F+IL +G
Sbjct: 522 SHSNVGIGTIVGSAVFNILFVIG 544
>AK096171-1|BAC04715.1| 352|Homo sapiens protein ( Homo sapiens
cDNA FLJ38852 fis, clone MESAN2010312, weakly similar to
Homo sapiens sodium/calcium exchanger NCKX3 (SLC24A3)
mRNA. ).
Length = 352
Score = 54.0 bits (124), Expect = 1e-06
Identities = 20/51 (39%), Positives = 32/51 (62%)
Query: 255 KITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFIMCIVWIGSLSYIVAWM 305
K+ + TWP+ + TIP+ KPR++ +F +TFI +WI SYI+ W+
Sbjct: 276 KVKWVFTWPLIFLLCVTIPNSSKPRWEKFFMVTFITATLWIAVFSYIMVWL 326
Score = 46.0 bits (104), Expect = 3e-04
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 78 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKGSWKWVSNMFKDNEE 137
I+V +LI I+DE + W+E +L+ LY YI IM Y+ +Q F K ++N N
Sbjct: 64 ISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFTVKQKSIAN---GNPV 120
Query: 138 KQDAENGKD 146
+ E G D
Sbjct: 121 NSELEAGND 129
Score = 44.8 bits (101), Expect = 6e-04
Identities = 19/39 (48%), Positives = 23/39 (58%)
Query: 1 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTI 39
++ DV PELF +VIG FIT GD+GVGTI
Sbjct: 26 LSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTI 64
Score = 32.3 bits (70), Expect = 3.7
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 309 IGDTLMIPDSVMGITFLAAGTSVPEAVSSVI 339
I + L + + V G TF+AAG+S PE +SVI
Sbjct: 20 ICERLHLSEDVAGATFMAAGSSTPELFASVI 50
>BC098360-1|AAH98360.1| 584|Homo sapiens SLC24A6 protein protein.
Length = 584
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 8/180 (4%)
Query: 267 VFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFL 325
V F D + PR F L F+ +WI + + V ++ +G + ++V+G+T L
Sbjct: 404 VTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLL 463
Query: 326 AAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWV 385
A G S+ +A S +A+Q F+IL+ +GL L++ S + H V
Sbjct: 464 AWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRS-----HTEV 518
Query: 386 KINSMGLEYSAIXXX--XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNV 443
K+ GL + F+L G L Y FL++A L E V
Sbjct: 519 KLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGV 578
>AY601760-1|AAT35808.1| 528|Homo sapiens Na+/Ca2+ K+ independent
exchanger short splice isoform protein.
Length = 528
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 8/180 (4%)
Query: 267 VFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFL 325
V F D + PR F L F+ +WI + + V ++ +G + ++V+G+T L
Sbjct: 348 VTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLL 407
Query: 326 AAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWV 385
A G S+ +A S +A+Q F+IL+ +GL L++ S + H V
Sbjct: 408 AWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRS-----HTEV 462
Query: 386 KINSMGLEYSAIXXX--XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNV 443
K+ GL + F+L G L Y FL++A L E V
Sbjct: 463 KLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGV 522
>AY601759-1|AAT35807.1| 584|Homo sapiens Na+/Ca2+ K+ independent
exchanger protein.
Length = 584
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 8/180 (4%)
Query: 267 VFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFL 325
V F D + PR F L F+ +WI + + V ++ +G + ++V+G+T L
Sbjct: 404 VTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLL 463
Query: 326 AAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWV 385
A G S+ +A S +A+Q F+IL+ +GL L++ S + H V
Sbjct: 464 AWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRS-----HTEV 518
Query: 386 KINSMGLEYSAIXXX--XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNV 443
K+ GL + F+L G L Y FL++A L E V
Sbjct: 519 KLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGV 578
>AK025886-1|BAB15271.1| 389|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22233 fis, clone HRC02016. ).
Length = 389
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 8/180 (4%)
Query: 267 VFLFTIPDCEKPRFKNWFP-LTFIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFL 325
V F D + PR F L F+ +WI + + V ++ +G + ++V+G+T L
Sbjct: 209 VTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLL 268
Query: 326 AAGTSVPEAVSSVIVAKQXXXXXXXXXXXXXXTFDILLCLGLPWLIKASLTPAEPGHYWV 385
A G S+ +A S +A+Q F+IL+ +GL L++ S + H V
Sbjct: 269 AWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRS-----HTEV 323
Query: 386 KINSMGLEYSAIXXX--XXXXXXXXXFWFNKFKLDAAVGRACLAMYAMFLILATLIELNV 443
K+ GL + F+L G L Y FL++A L E V
Sbjct: 324 KLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGV 383
>M91368-1|AAA35702.1| 973|Homo sapiens Na+/Ca+ exchanger protein.
Length = 973
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 758 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 805
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP+ +S + A Q
Sbjct: 806 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 865
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +G+ W I A
Sbjct: 866 SIGNVTGSNAVNVFLGIGVAWSIAA 890
Score = 38.3 bits (85), Expect = 0.056
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 18 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
PE+ ++VI G T GD+G TIVGSA FN+ + A C
Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
>BC098308-1|AAH98308.1| 335|Homo sapiens SLC8A1 protein protein.
Length = 335
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 120 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 167
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP+ +S + A Q
Sbjct: 168 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 227
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +G+ W I A
Sbjct: 228 SIGNVTGSNAVNVFLGIGVAWSIAA 252
>BC098285-1|AAH98285.1| 384|Homo sapiens SLC8A1 protein protein.
Length = 384
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 169 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 216
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP+ +S + A Q
Sbjct: 217 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 276
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +G+ W I A
Sbjct: 277 SIGNVTGSNAVNVFLGIGVAWSIAA 301
>AF128524-1|AAD26362.1| 960|Homo sapiens sodium-calcium exchanger
isoform NCX1.7 precursor protein.
Length = 960
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 745 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 792
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP+ +S + A Q
Sbjct: 793 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 852
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +G+ W I A
Sbjct: 853 SIGNVTGSNAVNVFLGIGVAWSIAA 877
Score = 38.3 bits (85), Expect = 0.056
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 18 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
PE+ ++VI G T GD+G TIVGSA FN+ + A C
Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
>AF108389-1|AAF08988.1| 937|Homo sapiens sodium/calcium exchanger
isoform NaCa3 protein.
Length = 937
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 722 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 769
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP+ +S + A Q
Sbjct: 770 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 829
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +G+ W I A
Sbjct: 830 SIGNVTGSNAVNVFLGIGVAWSIAA 854
Score = 38.3 bits (85), Expect = 0.056
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 18 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
PE+ ++VI G T GD+G TIVGSA FN+ + A C
Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
>AF108388-1|AAF08987.1| 960|Homo sapiens sodium/calcium exchanger
isoform NaCa7 protein.
Length = 960
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 745 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 792
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP+ +S + A Q
Sbjct: 793 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 852
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +G+ W I A
Sbjct: 853 SIGNVTGSNAVNVFLGIGVAWSIAA 877
Score = 38.3 bits (85), Expect = 0.056
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 18 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
PE+ ++VI G T GD+G TIVGSA FN+ + A C
Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
>AB209075-1|BAD92312.1| 411|Homo sapiens solute carrier family 8
(sodium/calcium exchanger), member 1 variant protein.
Length = 411
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 13/145 (8%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 196 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 243
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXXXX 348
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP+ +S + A Q
Sbjct: 244 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 303
Query: 349 XXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +G+ W I A
Sbjct: 304 SIGNVTGSNAVNVFLGIGVAWSIAA 328
>AJ745102-1|CAG33740.1| 298|Homo sapiens Na+/Ca2+ exchanger 3
protein.
Length = 298
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 129 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 188
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 189 DASIGNVTGSNAVNVFLGIGLAWSVAA 215
>AJ745101-1|CAG33739.1| 284|Homo sapiens Na+/Ca2+ exchanger 3
protein.
Length = 284
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 115 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 174
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 175 DASIGNVTGSNAVNVFLGIGLAWSVAA 201
>AJ508602-1|CAD48420.1| 771|Homo sapiens Na+/Ca2+ exchanger isoform
4 protein.
Length = 771
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 602 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 661
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 662 DASIGNVTGSNAVNVFLGIGLAWSVAA 688
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 22 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
+ V G GD+G TIVGSA FN+ + C
Sbjct: 3 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 35
>AJ304853-1|CAC40985.1| 924|Homo sapiens sodium/calcium exchanger
SCL8A3 protein.
Length = 924
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 755 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 814
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 815 DASIGNVTGSNAVNVFLGIGLAWSVAA 841
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 22 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
+ V G GD+G TIVGSA FN+ + C
Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
>AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchanger
SCL8A3 protein.
Length = 925
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 756 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 815
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 816 DASIGNVTGSNAVNVFLGIGLAWSVAA 842
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 22 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
+ V G GD+G TIVGSA FN+ + C
Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
>AF510502-1|AAN60791.1| 927|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 3 protein.
Length = 927
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 758 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 817
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 818 DASIGNVTGSNAVNVFLGIGLAWSVAA 844
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 22 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
+ V G GD+G TIVGSA FN+ + C
Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
>AF510501-1|AAN60790.1| 921|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 2 protein.
Length = 921
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 752 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 811
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 812 DASIGNVTGSNAVNVFLGIGLAWSVAA 838
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 22 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
+ V G GD+G TIVGSA FN+ + C
Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
>AF508982-1|AAM90955.1| 927|Homo sapiens Na+/Ca2+ exchanger isoform
3 protein.
Length = 927
Score = 44.4 bits (100), Expect = 9e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQ-XXX 346
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP+ +S A Q
Sbjct: 758 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 817
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L +GL W + A
Sbjct: 818 DASIGNVTGSNAVNVFLGIGLAWSVAA 844
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 22 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
+ V G GD+G TIVGSA FN+ + C
Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
>AB029010-1|BAA83039.1| 952|Homo sapiens KIAA1087 protein protein.
Length = 952
Score = 42.3 bits (95), Expect = 0.003
Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVPEAVSSVIVAKQXX-X 346
F + I+ IG L+ ++ + + G T+ + DSV + F+A GTS+P+ +S + A Q
Sbjct: 783 FGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCA 842
Query: 347 XXXXXXXXXXXTFDILLCLGLPWLIKA 373
++ L LG+ W + A
Sbjct: 843 DASIGNVTGSNAVNVFLGLGVAWSVAA 869
Score = 37.5 bits (83), Expect = 0.098
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 18 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
PE+ ++VI G G++G GTIVGSA FN+ V A C
Sbjct: 172 PEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVC 211
>AC007377-1|AAX81985.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 40.3 bits (90), Expect = 0.014
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 12/103 (11%)
Query: 230 EDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVFLFTIPDCEKPRFKNWFPLTFI 289
ED+ D E G E K PS C + +T ++F F +P E + W FI
Sbjct: 155 EDDDDDECGEE----KLPS---CFDYVMHFLTVFWKVLFAF-VPPTEY--WNGW--ACFI 202
Query: 290 MCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVP 332
+ I+ IG L+ + + + G T+ + DSV + F+A GTSVP
Sbjct: 203 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVP 245
>AC007281-1|AAF19237.1| 603|Homo sapiens unknown protein.
Length = 603
Score = 38.3 bits (85), Expect = 0.056
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 18 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 54
PE+ ++VI G T GD+G TIVGSA FN+ + A C
Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
>AF461266-1|AAL67520.1| 606|Homo sapiens RUFY2 protein.
Length = 606
Score = 37.1 bits (82), Expect = 0.13
Identities = 30/126 (23%), Positives = 61/126 (48%), Gaps = 4/126 (3%)
Query: 134 DNEEKQDAENGKDLKLST-HILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDK 192
+++ +QD EN +++S H +++ + + ++ H LRQ +E ++++ K
Sbjct: 308 ESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQK 367
Query: 193 VSASEEG-KDKN-VNIDMDSKPNEMEIASPE-ENLYQPTAEDNTDVEDGSENSLWKWPSN 249
+ SE+G K+KN + ++ K N++ A + E Q + + ED E L + S
Sbjct: 368 LQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSK 427
Query: 250 KSCLAK 255
L K
Sbjct: 428 SDSLQK 433
>AF411980-1|AAL04164.1| 590|Homo sapiens Run- and FYVE-domain
containing protein Rabip4R protein.
Length = 590
Score = 37.1 bits (82), Expect = 0.13
Identities = 30/126 (23%), Positives = 61/126 (48%), Gaps = 4/126 (3%)
Query: 134 DNEEKQDAENGKDLKLST-HILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDK 192
+++ +QD EN +++S H +++ + + ++ H LRQ +E ++++ K
Sbjct: 292 ESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQK 351
Query: 193 VSASEEG-KDKN-VNIDMDSKPNEMEIASPE-ENLYQPTAEDNTDVEDGSENSLWKWPSN 249
+ SE+G K+KN + ++ K N++ A + E Q + + ED E L + S
Sbjct: 352 LQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSK 411
Query: 250 KSCLAK 255
L K
Sbjct: 412 SDSLQK 417
>AB040970-1|BAA96061.1| 619|Homo sapiens KIAA1537 protein protein.
Length = 619
Score = 37.1 bits (82), Expect = 0.13
Identities = 30/126 (23%), Positives = 61/126 (48%), Gaps = 4/126 (3%)
Query: 134 DNEEKQDAENGKDLKLST-HILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDK 192
+++ +QD EN +++S H +++ + + ++ H LRQ +E ++++ K
Sbjct: 321 ESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQK 380
Query: 193 VSASEEG-KDKN-VNIDMDSKPNEMEIASPE-ENLYQPTAEDNTDVEDGSENSLWKWPSN 249
+ SE+G K+KN + ++ K N++ A + E Q + + ED E L + S
Sbjct: 381 LQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSK 440
Query: 250 KSCLAK 255
L K
Sbjct: 441 SDSLQK 446
>BC114217-1|AAI14218.1| 210|Homo sapiens SLC8A3 protein protein.
Length = 210
Score = 36.3 bits (80), Expect = 0.23
Identities = 18/45 (40%), Positives = 28/45 (62%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVP 332
F + I+ IG L+ I+ + + G T+ + DSV + F+A GTSVP
Sbjct: 115 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVP 159
>AF177377-1|AAG09279.2| 981|Homo sapiens cytoplasmic protein
protein.
Length = 981
Score = 34.7 bits (76), Expect = 0.69
Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 171 KTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAE 230
K P Q K++ S D S ++ AS + + + + + E + A+P +++ +P+
Sbjct: 119 KEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPA 178
Query: 231 DNT----DVEDGSENSLWKWPSNKSCLAKITK 258
+ + + D S N L K PS + K+TK
Sbjct: 179 EKSHNSWENSDDSRNKLSKIPSTPKLIPKVTK 210
>AC006038-1|AAY15086.1| 911|Homo sapiens unknown protein.
Length = 911
Score = 34.7 bits (76), Expect = 0.69
Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 171 KTSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAE 230
K P Q K++ S D S ++ AS + + + + + E + A+P +++ +P+
Sbjct: 49 KEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPA 108
Query: 231 DNT----DVEDGSENSLWKWPSNKSCLAKITK 258
+ + + D S N L K PS + K+TK
Sbjct: 109 EKSHNSWENSDDSRNKLSKIPSTPKLIPKVTK 140
>BC093405-1|AAH93405.1| 550|Homo sapiens PHF20 protein protein.
Length = 550
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>BC080598-1|AAH80598.1| 550|Homo sapiens PHF20 protein protein.
Length = 550
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>BC048210-1|AAH48210.1| 549|Homo sapiens PHF20 protein protein.
Length = 549
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AY134747-1|AAN08621.1| 550|Homo sapiens medulloblastoma antigen
MU-MB-50.72 protein.
Length = 550
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AY027523-1|AAK13046.1| 1012|Homo sapiens transcription factor TZP
protein.
Length = 1012
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AL109965-3|CAI19247.1| 1012|Homo sapiens PHD finger protein 20
protein.
Length = 1012
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AL109965-2|CAM27594.1| 549|Homo sapiens PHD finger protein 20
protein.
Length = 549
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AL109965-1|CAI19246.1| 543|Homo sapiens PHD finger protein 20
protein.
Length = 543
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AL078461-5|CAI43148.1| 256|Homo sapiens PHD finger protein 20
protein.
Length = 256
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 104 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 150
>AL078461-3|CAI43145.1| 1012|Homo sapiens PHD finger protein 20
protein.
Length = 1012
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AL078461-2|CAI43146.2| 549|Homo sapiens PHD finger protein 20
protein.
Length = 549
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AL078461-1|CAI43144.1| 543|Homo sapiens PHD finger protein 20
protein.
Length = 543
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>AF348207-1|AAK19748.1| 639|Homo sapiens C2H2 zinc finger protein
protein.
Length = 639
Score = 34.3 bits (75), Expect = 0.91
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 181 EKILESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQP 227
EK L + DK + SE ++ + + +D KP + SP+ENL +P
Sbjct: 210 EKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREP 256
>M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase
protein.
Length = 1142
Score = 33.1 bits (72), Expect = 2.1
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
Query: 128 VSNMFKDNEEKQDAENGKDLKLSTHILKID--VPIEQRHQHNGN--IKTSPLRQDAKEKI 183
++N+FKD ++ + + D +STH LK+ +E +H G +TS L ++ ++
Sbjct: 228 INNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEM 287
Query: 184 --LESVDVSDKVSASEEGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSEN 241
S D V E N+ I KPN + + E+N + +N D +D +N
Sbjct: 288 NWFHSND-GGNVLYYEVMVTGNLGIQWRHKPNVVSV-EKEKNKLKRKKLENKDKKDEEKN 345
Query: 242 SLWKWPSNKSCLAKITKIV 260
+ + +N S +IT IV
Sbjct: 346 KIREEWNNFSFFPEITHIV 364
>AL512764-1|CAC21681.1| 793|Homo sapiens hypothetical protein
protein.
Length = 793
Score = 33.1 bits (72), Expect = 2.1
Identities = 16/45 (35%), Positives = 28/45 (62%)
Query: 288 FIMCIVWIGSLSYIVAWMITIIGDTLMIPDSVMGITFLAAGTSVP 332
F + I+ IG L+ ++ + + G T+ + DSV + F+A GTS+P
Sbjct: 548 FGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIP 592
>AF510503-1|AAN60792.1| 620|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 4 protein.
Length = 620
Score = 33.1 bits (72), Expect = 2.1
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 22 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 54
+ V G GD+G TIVGSA FN+ + C
Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 31.9 bits (69), Expect = 4.9
Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 117 IQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
I+ +K + + + N K+ E A G + +D PIE+ HQ +I+ R
Sbjct: 2249 IKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2308
Query: 177 QDAKEK----ILESVDVSDKVSASEEGKDKNVNIDMD-SKPNEMEIASPEEN 223
+A EK +L+ + S+ + +G+ +N+ +++ ++ N+ A EN
Sbjct: 2309 LEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAEN 2360
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 31.9 bits (69), Expect = 4.9
Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 117 IQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
I+ +K + + + N K+ E A G + +D PIE+ HQ +I+ R
Sbjct: 153 IKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 212
Query: 177 QDAKEK----ILESVDVSDKVSASEEGKDKNVNIDMD-SKPNEMEIASPEEN 223
+A EK +L+ + S+ + +G+ +N+ +++ ++ N+ A EN
Sbjct: 213 LEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAEN 264
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 31.9 bits (69), Expect = 4.9
Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 117 IQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
I+ +K + + + N K+ E A G + +D PIE+ HQ +I+ R
Sbjct: 2346 IKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2405
Query: 177 QDAKEK----ILESVDVSDKVSASEEGKDKNVNIDMD-SKPNEMEIASPEEN 223
+A EK +L+ + S+ + +G+ +N+ +++ ++ N+ A EN
Sbjct: 2406 LEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAEN 2457
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 31.9 bits (69), Expect = 4.9
Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 117 IQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
I+ +K + + + N K+ E A G + +D PIE+ HQ +I+ R
Sbjct: 2250 IKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2309
Query: 177 QDAKEK----ILESVDVSDKVSASEEGKDKNVNIDMD-SKPNEMEIASPEEN 223
+A EK +L+ + S+ + +G+ +N+ +++ ++ N+ A EN
Sbjct: 2310 LEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAEN 2361
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 31.9 bits (69), Expect = 4.9
Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 117 IQNFAKGSWKWVSNMFKDNEEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLR 176
I+ +K + + + N K+ E A G + +D PIE+ HQ +I+ R
Sbjct: 2250 IKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2309
Query: 177 QDAKEK----ILESVDVSDKVSASEEGKDKNVNIDMD-SKPNEMEIASPEEN 223
+A EK +L+ + S+ + +G+ +N+ +++ ++ N+ A EN
Sbjct: 2310 LEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAEN 2361
>X98332-1|CAA66977.1| 554|Homo sapiens organic cation transporter
protein.
Length = 554
Score = 31.5 bits (68), Expect = 6.4
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 9/91 (9%)
Query: 22 VNVIGTFITEGDIG-VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLA-YGIT 79
V + G FI I VG I A+ N+LA AAC + + L W + C+ GIT
Sbjct: 385 VEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL-VMIFISPDLHWLNIIIMCVGRMGIT 443
Query: 80 VSI-LICIIHDEYVQWYEAFLLVSLYGVYIC 109
++I +IC+++ E Y F V GV +C
Sbjct: 444 IAIQMICLVNAEL---YPTF--VRNLGVMVC 469
>U77086-1|AAB67703.1| 554|Homo sapiens organic cation transporter 1
protein.
Length = 554
Score = 31.5 bits (68), Expect = 6.4
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 9/91 (9%)
Query: 22 VNVIGTFITEGDIG-VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLA-YGIT 79
V + G FI I VG I A+ N+LA AAC + + L W + C+ GIT
Sbjct: 385 VEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL-VMIFISPDLHWLNIIIMCVGRMGIT 443
Query: 80 VSI-LICIIHDEYVQWYEAFLLVSLYGVYIC 109
++I +IC+++ E Y F V GV +C
Sbjct: 444 IAIQMICLVNAEL---YPTF--VRNLGVMVC 469
>CR456730-1|CAG33011.1| 422|Homo sapiens NOL4 protein.
Length = 422
Score = 31.5 bits (68), Expect = 6.4
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 142 ENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKD 201
+NGK L T ++ ++PI + + ++ +QD E +E SD+ S+ +
Sbjct: 62 DNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIE----SDEFDMSDSTRM 117
Query: 202 KNVNIDMDSKPNEMEIASPEENLYQPTAEDN 232
VN D+ S E + SP +NL+ +D+
Sbjct: 118 SAVNSDLSSNLEE-RMQSP-QNLHGQQDDDS 146
>BT006763-1|AAP35409.1| 422|Homo sapiens nucleolar protein 4
protein.
Length = 422
Score = 31.5 bits (68), Expect = 6.4
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 142 ENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKD 201
+NGK L T ++ ++PI + + ++ +QD E +E SD+ S+ +
Sbjct: 62 DNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIE----SDEFDMSDSTRM 117
Query: 202 KNVNIDMDSKPNEMEIASPEENLYQPTAEDN 232
VN D+ S E + SP +NL+ +D+
Sbjct: 118 SAVNSDLSSNLEE-RMQSP-QNLHGQQDDDS 146
>BC126364-1|AAI26365.1| 554|Homo sapiens solute carrier family 22
(organic cation transporter), member 1 protein.
Length = 554
Score = 31.5 bits (68), Expect = 6.4
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 9/91 (9%)
Query: 22 VNVIGTFITEGDIG-VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLA-YGIT 79
V + G FI I VG I A+ N+LA AAC + + L W + C+ GIT
Sbjct: 385 VEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL-VMIFISPDLHWLNIIIMCVGRMGIT 443
Query: 80 VSI-LICIIHDEYVQWYEAFLLVSLYGVYIC 109
++I +IC+++ E Y F V GV +C
Sbjct: 444 IAIQMICLVNAEL---YPTF--VRNLGVMVC 469
>BC041092-1|AAH41092.1| 403|Homo sapiens RUN and FYVE domain
containing 2 protein.
Length = 403
Score = 31.5 bits (68), Expect = 6.4
Identities = 21/88 (23%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Query: 134 DNEEKQDAENGKDLKLST-HILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDK 192
+++ +QD EN +++S H +++ + + ++ H LRQ +E ++++ K
Sbjct: 274 ESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQK 333
Query: 193 VSASEEG-KDKN-VNIDMDSKPNEMEIA 218
+ SE+G K+KN + ++ K N++ A
Sbjct: 334 LQGSEDGLKEKNEIIARLEEKTNKITAA 361
>BC000313-1|AAH00313.1| 422|Homo sapiens NOL4 protein protein.
Length = 422
Score = 31.5 bits (68), Expect = 6.4
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 142 ENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKD 201
+NGK L T ++ ++PI + + ++ +QD E +E SD+ S+ +
Sbjct: 62 DNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIE----SDEFDMSDSTRM 117
Query: 202 KNVNIDMDSKPNEMEIASPEENLYQPTAEDN 232
VN D+ S E + SP +NL+ +D+
Sbjct: 118 SAVNSDLSSNLEE-RMQSP-QNLHGQQDDDS 146
>AL353625-3|CAH72016.1| 554|Homo sapiens solute carrier family 22
(organic cation transporter), member 1 protein.
Length = 554
Score = 31.5 bits (68), Expect = 6.4
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 9/91 (9%)
Query: 22 VNVIGTFITEGDIG-VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLA-YGIT 79
V + G FI I VG I A+ N+LA AAC + + L W + C+ GIT
Sbjct: 385 VEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL-VMIFISPDLHWLNIIIMCVGRMGIT 443
Query: 80 VSI-LICIIHDEYVQWYEAFLLVSLYGVYIC 109
++I +IC+++ E Y F V GV +C
Sbjct: 444 IAIQMICLVNAEL---YPTF--VRNLGVMVC 469
>AJ243995-1|CAB95971.1| 554|Homo sapiens protein ( Homo sapiens
partial oct1 gene for organic cation transporter, exon 1
and joined CDS. ).
Length = 554
Score = 31.5 bits (68), Expect = 6.4
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 9/91 (9%)
Query: 22 VNVIGTFITEGDIG-VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLA-YGIT 79
V + G FI I VG I A+ N+LA AAC + + L W + C+ GIT
Sbjct: 385 VEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL-VMIFISPDLHWLNIIIMCVGRMGIT 443
Query: 80 VSI-LICIIHDEYVQWYEAFLLVSLYGVYIC 109
++I +IC+++ E Y F V GV +C
Sbjct: 444 IAIQMICLVNAEL---YPTF--VRNLGVMVC 469
>AB017800-1|BAA34576.1| 524|Homo sapiens nolp protein.
Length = 524
Score = 31.5 bits (68), Expect = 6.4
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 142 ENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASEEGKD 201
+NGK L T ++ ++PI + + ++ +QD E +E SD+ S+ +
Sbjct: 62 DNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIE----SDEFDMSDSTRM 117
Query: 202 KNVNIDMDSKPNEMEIASPEENLYQPTAEDN 232
VN D+ S E + SP +NL+ +D+
Sbjct: 118 SAVNSDLSSNLEE-RMQSP-QNLHGQQDDDS 146
>Z84487-2|CAI42675.1| 2454|Homo sapiens alpha thalassemia/mental
retardation syndrome X-linked (RAD54 homolog, S. cerev
protein.
Length = 2454
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1080 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1133
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1134 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1192
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1193 ENLVLSSHTGF 1203
>Z84487-1|CAI42674.1| 2492|Homo sapiens alpha thalassemia/mental
retardation syndrome X-linked (RAD54 homolog, S. cerev
protein.
Length = 2492
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1118 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1230
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1231 ENLVLSSHTGF 1241
>U97103-1|AAC51657.1| 2375|Homo sapiens X-linked nuclear protein
protein.
Length = 2375
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1001 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1054
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1055 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1113
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1114 ENLVLSSHTGF 1124
>U75653-1|AAC51655.1| 2492|Homo sapiens zinc finger helicase protein.
Length = 2492
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1118 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1230
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1231 ENLVLSSHTGF 1241
>U72938-1|AAB49971.2| 2454|Homo sapiens putative DNA dependent ATPase
and helicase protein.
Length = 2454
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1080 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1133
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1134 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1192
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1193 ENLVLSSHTGF 1203
>U72937-1|AAB49970.2| 2492|Homo sapiens putative DNA dependent ATPase
and helicase protein.
Length = 2492
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1118 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1230
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1231 ENLVLSSHTGF 1241
>U72936-1|AAB49969.1| 2288|Homo sapiens putative DNA dependent ATPase
and helicase protein.
Length = 2288
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 914 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 967
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 968 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1026
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1027 ENLVLSSHTGF 1037
>U72935-3|AAB40700.1| 2288|Homo sapiens putative DNA dependent ATPase
and helicase protein.
Length = 2288
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 914 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 967
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 968 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1026
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1027 ENLVLSSHTGF 1037
>U72935-2|AAB40699.1| 2337|Homo sapiens putative DNA dependent ATPase
and helicase protein.
Length = 2337
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 963 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1016
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1017 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1075
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1076 ENLVLSSHTGF 1086
>U72935-1|AAB40698.1| 2375|Homo sapiens putative DNA dependent ATPase
and helicase protein.
Length = 2375
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1001 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1054
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1055 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1113
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1114 ENLVLSSHTGF 1124
>U09820-1|AAC50069.1| 1641|Homo sapiens helicase II protein.
Length = 1641
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 259 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 312
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 313 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 371
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 372 ENLVLSSHTGF 382
>L34363-1|AAA20872.1| 1298|Homo sapiens X-linked nuclear protein
protein.
Length = 1298
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/120 (19%), Positives = 50/120 (41%), Gaps = 3/120 (2%)
Query: 151 THILKIDVPIEQRHQHNGNIK--TSPLRQDAKEKILESVDVSDKVSASEEGKDKNVNIDM 208
T +++ IE R + N + K T ++ + E +K K I
Sbjct: 4 TLLIRDSTRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVK 63
Query: 209 DSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKITKIVTWPIHLVF 268
+ K N + ++ + T+ ++D+ED +NS+ + S++ + +T+ + H F
Sbjct: 64 EKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGF 122
>EF467914-1|ABO43036.1| 2492|Homo sapiens alpha thalassemia/mental
retardation syndrome X-linked protein.
Length = 2492
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1118 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1230
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1231 ENLVLSSHTGF 1241
>AL354890-2|CAI21914.1| 810|Homo sapiens ecotropic viral
integration site 5 protein.
Length = 810
Score = 31.1 bits (67), Expect = 8.5
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 136 EEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSA 195
+E ++ K L+ +LK + ++H+ + N + Q KE + + ++ A
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLSEAESQCA 480
Query: 196 SEEGKDKNVNIDM--DSKPNEMEIASPEENL 224
+E +DK ++I+ +S P+E IA +E L
Sbjct: 481 LKEMQDKVLDIEKRNNSLPDENNIARLQEEL 511
>AL133332-1|CAC19437.2| 810|Homo sapiens ecotropic viral
integration site 5 protein.
Length = 810
Score = 31.1 bits (67), Expect = 8.5
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 136 EEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSA 195
+E ++ K L+ +LK + ++H+ + N + Q KE + + ++ A
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLSEAESQCA 480
Query: 196 SEEGKDKNVNIDM--DSKPNEMEIASPEENL 224
+E +DK ++I+ +S P+E IA +E L
Sbjct: 481 LKEMQDKVLDIEKRNNSLPDENNIARLQEEL 511
>AL121874-2|CAB90351.2| 2454|Homo sapiens alpha thalassemia/mental
retardation syndrome X-linked (RAD54 homolog, S. cerev
protein.
Length = 2454
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1080 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1133
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1134 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1192
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1193 ENLVLSSHTGF 1203
>AL121874-1|CAI40710.1| 2492|Homo sapiens alpha thalassemia/mental
retardation syndrome X-linked (RAD54 homolog, S. cerev
protein.
Length = 2492
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1118 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1230
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1231 ENLVLSSHTGF 1241
>AL109753-2|CAI43115.1| 2492|Homo sapiens alpha thalassemia/mental
retardation syndrome X-linked (RAD54 homolog, S. cerev
protein.
Length = 2492
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1118 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1230
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1231 ENLVLSSHTGF 1241
>AL109753-1|CAI43116.1| 2454|Homo sapiens alpha thalassemia/mental
retardation syndrome X-linked (RAD54 homolog, S. cerev
protein.
Length = 2454
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1080 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1133
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1134 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1192
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1193 ENLVLSSHTGF 1203
>AK125340-1|BAC86137.1| 292|Homo sapiens protein ( Homo sapiens
cDNA FLJ43350 fis, clone NT2RP7004123. ).
Length = 292
Score = 31.1 bits (67), Expect = 8.5
Identities = 33/120 (27%), Positives = 58/120 (48%), Gaps = 13/120 (10%)
Query: 132 FKDNEEKQDAENGK----DLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESV 187
F+ N ++QD NGK +K STH + ++ H+ K S +Q +K E+
Sbjct: 121 FETNSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQK-KRSHKKQKKSKK--EAT 177
Query: 188 DVSDKVSASEEGKDKNVNIDMDSK-PNEMEIASPEENLYQPT----AEDNTDVEDGSENS 242
D++ S+SE ++ + K P++ + S +++L +P AE NT D S +S
Sbjct: 178 DITAD-SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASS 236
>AF042345-1|AAC16041.1| 607|Homo sapiens truncated EVI5 protein.
Length = 607
Score = 31.1 bits (67), Expect = 8.5
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 136 EEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSA 195
+E ++ K L+ +LK + ++H+ + N + Q KE + + ++ A
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLSEAESQCA 480
Query: 196 SEEGKDKNVNIDM--DSKPNEMEIASPEENL 224
+E +DK ++I+ +S P+E IA +E L
Sbjct: 481 LKEMQDKVLDIEKRNNSLPDENNIARLQEEL 511
>AF008915-1|AAC16031.1| 810|Homo sapiens EVI-5 homolog protein.
Length = 810
Score = 31.1 bits (67), Expect = 8.5
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 136 EEKQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSA 195
+E ++ K L+ +LK + ++H+ + N + Q KE + + ++ A
Sbjct: 421 KEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLSEAESQCA 480
Query: 196 SEEGKDKNVNIDM--DSKPNEMEIASPEENL 224
+E +DK ++I+ +S P+E IA +E L
Sbjct: 481 LKEMQDKVLDIEKRNNSLPDENNIARLQEEL 511
>AB209545-1|BAD92782.1| 1224|Homo sapiens transcriptional regulator
ATRX isoform 1 variant protein.
Length = 1224
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 415 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 468
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 469 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 527
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 528 ENLVLSSHTGF 538
>AB208928-1|BAD92165.1| 1383|Homo sapiens transcriptional regulator
ATRX isoform 2 variant protein.
Length = 1383
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1083 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1136
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1137 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1195
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1196 ENLVLSSHTGF 1206
>AB102641-1|BAC81110.1| 2492|Homo sapiens ATRX protein.
Length = 2492
Score = 31.1 bits (67), Expect = 8.5
Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 138 KQDAENGKDLKLSTHILKIDVPIEQRHQHNGNIKTSPLRQDAKEKILESVDVSDKVSASE 197
K+D N D +L + + +R + T ++ + E +K
Sbjct: 1118 KEDGCNSSDKRLKR------IELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171
Query: 198 EGKDKNVNIDMDSKPNEMEIASPEENLYQPTAEDNTDVEDGSENSLWKWPSNKSCLAKIT 257
K I + K N + ++ + T+ ++D+ED +NS+ + S++ + +T
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQA-DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT 1230
Query: 258 KIVTWPIHLVF 268
+ + H F
Sbjct: 1231 ENLVLSSHTGF 1241
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.138 0.435
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 65,752,579
Number of Sequences: 224733
Number of extensions: 2799555
Number of successful extensions: 12672
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 12403
Number of HSP's gapped (non-prelim): 274
length of query: 459
length of database: 73,234,838
effective HSP length: 92
effective length of query: 367
effective length of database: 52,559,402
effective search space: 19289300534
effective search space used: 19289300534
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 67 (31.1 bits)
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