Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000535-TA|BGIBMGA000535-PA|IPR008937|Ras guanine
nucleotide exchange factor, IPR001895|Guanine-nucleotide dissociation
stimulator CDC25
(433 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q28EC1 Cluster: Ras-GEF domain-containing family member... 198 3e-49
UniRef50_Q4SDT4 Cluster: Chromosome 1 SCAF14632, whole genome sh... 180 7e-44
UniRef50_Q8N431 Cluster: Ras-GEF domain-containing family member... 171 2e-41
UniRef50_A7S619 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 162 1e-38
UniRef50_Q8N9B8 Cluster: Ras-GEF domain-containing family member... 155 2e-36
UniRef50_Q8SYL9 Cluster: RE54096p; n=4; Sophophora|Rep: RE54096p... 150 6e-35
UniRef50_Q7QFQ1 Cluster: ENSANGP00000007336; n=1; Anopheles gamb... 149 1e-34
UniRef50_Q21758 Cluster: Putative uncharacterized protein; n=2; ... 117 7e-25
UniRef50_Q95S44 Cluster: GM09415p; n=4; Sophophora|Rep: GM09415p... 116 1e-24
UniRef50_Q9VQM8 Cluster: CG15405-PA; n=4; Diptera|Rep: CG15405-P... 113 1e-23
UniRef50_A4RFZ9 Cluster: Putative uncharacterized protein; n=2; ... 80 1e-13
UniRef50_Q4WNQ3 Cluster: Ras guanine-nucleotide exchange protein... 79 2e-13
UniRef50_A1CGW5 Cluster: Ras guanine-nucleotide exchange protein... 77 1e-12
UniRef50_Q23867 Cluster: Aimless RasGEF; n=3; Dictyostelium disc... 76 2e-12
UniRef50_Q0UTD8 Cluster: Putative uncharacterized protein; n=1; ... 75 5e-12
UniRef50_UPI00015A6BDA Cluster: UPI00015A6BDA related cluster; n... 73 1e-11
UniRef50_Q6C637 Cluster: YlCDC25 protein; n=2; Yarrowia lipolyti... 73 2e-11
UniRef50_UPI0000498DA7 Cluster: Ras guanine nucleotide exchange ... 71 6e-11
UniRef50_A7SLX0 Cluster: Predicted protein; n=1; Nematostella ve... 71 8e-11
UniRef50_Q4RS43 Cluster: Chromosome 7 SCAF15001, whole genome sh... 70 1e-10
UniRef50_Q54F62 Cluster: RasGEF domain-containing protein; n=2; ... 70 1e-10
UniRef50_Q55CK1 Cluster: Ras guanine nucleotide exchange factor;... 69 2e-10
UniRef50_Q8IZJ4 Cluster: Ral-GDS-related protein; n=32; Catarrhi... 69 2e-10
UniRef50_UPI00006A087A Cluster: Ral guanine nucleotide dissociat... 67 7e-10
UniRef50_Q5K6X7 Cluster: Cell division control protein 25, putat... 67 7e-10
UniRef50_Q552M5 Cluster: RasGEF domain-containing protein; n=2; ... 67 1e-09
UniRef50_Q9Y4G8 Cluster: Rap guanine nucleotide exchange factor ... 67 1e-09
UniRef50_O15059 Cluster: Ral GEF with PH domain and SH3-binding ... 66 2e-09
UniRef50_A2QFY6 Cluster: Contig An03c0040, complete genome; n=2;... 66 2e-09
UniRef50_Q16MY3 Cluster: Ral guanine nucleotide exchange factor ... 66 2e-09
UniRef50_Q875L6 Cluster: Guanyl nucleotide exchange factor Sql2;... 66 2e-09
UniRef50_Q95WR8 Cluster: PXF isoform C; n=4; Caenorhabditis|Rep:... 65 3e-09
UniRef50_Q7Q955 Cluster: ENSANGP00000013079; n=1; Anopheles gamb... 65 3e-09
UniRef50_Q7S0V9 Cluster: Putative uncharacterized protein NCU097... 64 5e-09
UniRef50_Q3MIN7 Cluster: Ral guanine nucleotide dissociation sti... 64 5e-09
UniRef50_UPI000069F86C Cluster: Ral guanine nucleotide dissociat... 64 7e-09
UniRef50_Q6CRG2 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 64 7e-09
UniRef50_Q9NZL6 Cluster: Ral guanine nucleotide dissociation sti... 64 7e-09
UniRef50_P28818 Cluster: Guanine nucleotide-releasing protein; n... 64 7e-09
UniRef50_Q54RZ8 Cluster: RasGEF; n=2; Dictyostelium discoideum|R... 64 9e-09
UniRef50_O14827 Cluster: Ras protein-specific guanine nucleotide... 63 1e-08
UniRef50_UPI00015616A3 Cluster: PREDICTED: similar to ral guanin... 63 2e-08
UniRef50_Q9DE48 Cluster: Ras-associated protein; n=11; Clupeocep... 63 2e-08
UniRef50_Q54H95 Cluster: Putative uncharacterized protein; n=1; ... 63 2e-08
UniRef50_UPI00015616DC Cluster: PREDICTED: hypothetical protein,... 62 3e-08
UniRef50_UPI00004D6636 Cluster: ral guanine nucleotide dissociat... 62 3e-08
UniRef50_Q4RPN7 Cluster: Chromosome 12 SCAF15007, whole genome s... 62 3e-08
UniRef50_Q12967 Cluster: Ral guanine nucleotide dissociation sti... 62 3e-08
UniRef50_Q8TEU7 Cluster: Rap guanine nucleotide exchange factor ... 62 4e-08
UniRef50_Q0E949 Cluster: CG5522-PA, isoform A; n=5; Endopterygot... 61 5e-08
UniRef50_Q54H67 Cluster: Ras guanine nucleotide exchange factor;... 61 6e-08
UniRef50_UPI00015A741B Cluster: Hypothetical protein; n=3; Danio... 60 8e-08
UniRef50_A4QP96 Cluster: Putative uncharacterized protein; n=4; ... 60 8e-08
UniRef50_Q0ULM6 Cluster: Putative uncharacterized protein; n=1; ... 60 8e-08
UniRef50_Q13972 Cluster: Guanine nucleotide-releasing protein; n... 60 8e-08
UniRef50_Q19852 Cluster: Putative uncharacterized protein F28B4.... 60 1e-07
UniRef50_A4QNU6 Cluster: Zgc:162151 protein; n=6; Euteleostomi|R... 60 1e-07
UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella ve... 60 1e-07
UniRef50_A7SDN8 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 60 1e-07
UniRef50_A3LZZ6 Cluster: Predicted protein; n=2; Pichia|Rep: Pre... 60 1e-07
UniRef50_Q555R4 Cluster: Ras guanine nucleotide exchange factor;... 59 2e-07
UniRef50_Q02342 Cluster: Cell division control protein 25; n=1; ... 59 2e-07
UniRef50_UPI00015616C2 Cluster: PREDICTED: similar to ral guanin... 59 3e-07
UniRef50_UPI0000E47C73 Cluster: PREDICTED: similar to conserved ... 59 3e-07
UniRef50_Q179F5 Cluster: Guanine nucleotide exchange factor; n=2... 59 3e-07
UniRef50_A7SU64 Cluster: Predicted protein; n=1; Nematostella ve... 59 3e-07
UniRef50_UPI0000E478B1 Cluster: PREDICTED: similar to RALGPS1 pr... 58 3e-07
UniRef50_A6R1V9 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07
UniRef50_P04821 Cluster: Cell division control protein 25; n=2; ... 58 3e-07
UniRef50_Q5TND5 Cluster: ENSANGP00000025467; n=1; Anopheles gamb... 58 4e-07
UniRef50_Q553C1 Cluster: Ras guanine nucleotide exchange factor;... 58 4e-07
UniRef50_A6R7Z9 Cluster: Putative uncharacterized protein; n=1; ... 58 4e-07
UniRef50_Q6C867 Cluster: Similarities with sp|P43069 Candida alb... 58 6e-07
UniRef50_Q5K7Q6 Cluster: Putative uncharacterized protein; n=1; ... 58 6e-07
UniRef50_P14771 Cluster: Guanine nucleotide exchange factor SDC2... 58 6e-07
UniRef50_Q8IS10 Cluster: Nucleotide exchange factor RasGEF P; n=... 57 8e-07
UniRef50_A7TNK1 Cluster: Putative uncharacterized protein; n=1; ... 57 8e-07
UniRef50_Q8IV61 Cluster: RAS guanyl-releasing protein 3; n=79; E... 57 8e-07
UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p - ... 57 1e-06
UniRef50_P26674 Cluster: Protein ste6; n=1; Schizosaccharomyces ... 57 1e-06
UniRef50_Q4SD50 Cluster: Chromosome 1 SCAF14643, whole genome sh... 56 2e-06
UniRef50_A2R650 Cluster: Similarity: N-terminal half differs fro... 56 2e-06
UniRef50_P43069 Cluster: Cell division control protein 25; n=5; ... 56 2e-06
UniRef50_UPI00015B5B5D Cluster: PREDICTED: similar to conserved ... 56 2e-06
UniRef50_UPI00015B5B51 Cluster: PREDICTED: similar to ENSANGP000... 56 2e-06
UniRef50_UPI0000DB6F3E Cluster: PREDICTED: similar to Gef26 CG94... 56 2e-06
UniRef50_A7S186 Cluster: Predicted protein; n=1; Nematostella ve... 56 2e-06
UniRef50_Q6P112 Cluster: Ral guanine nucleotide dissociation sti... 56 2e-06
UniRef50_Q6FVA6 Cluster: Candida glabrata strain CBS138 chromoso... 55 3e-06
UniRef50_Q4PAN1 Cluster: Putative uncharacterized protein; n=1; ... 55 4e-06
UniRef50_UPI00005A1264 Cluster: PREDICTED: similar to Ral guanin... 54 6e-06
UniRef50_Q95V18 Cluster: Guanine nucleotide exchange factor; n=3... 54 6e-06
UniRef50_Q55GH9 Cluster: RasGEF domain-containing protein; n=1; ... 54 6e-06
UniRef50_Q555T3 Cluster: Ras guanine nucleotide exchange factor;... 54 6e-06
UniRef50_Q9USU1 Cluster: Exchange factor Cdc25p-like; n=1; Schiz... 54 6e-06
UniRef50_Q0UD52 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06
UniRef50_UPI0001561664 Cluster: PREDICTED: similar to ral guanin... 54 7e-06
UniRef50_Q5B8H1 Cluster: Putative uncharacterized protein; n=1; ... 54 7e-06
UniRef50_UPI0001561431 Cluster: PREDICTED: similar to pleckstrin... 54 1e-05
UniRef50_Q8MVR0 Cluster: Cyclic GMP-binding protein D; n=2; Dict... 54 1e-05
UniRef50_Q1DXK6 Cluster: Putative uncharacterized protein; n=1; ... 54 1e-05
UniRef50_A7TSP6 Cluster: Putative uncharacterized protein; n=1; ... 54 1e-05
UniRef50_Q17MY4 Cluster: Ral guanine nucleotide exchange factor,... 53 1e-05
UniRef50_A7TRY3 Cluster: Putative uncharacterized protein; n=1; ... 53 1e-05
UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor ... 53 1e-05
UniRef50_UPI0000E1F333 Cluster: PREDICTED: RAS guanyl releasing ... 53 2e-05
UniRef50_Q9UL65 Cluster: RAS guanyl-releasing protein 2; n=35; E... 53 2e-05
UniRef50_UPI00015B534D Cluster: PREDICTED: similar to CG5522-PD;... 52 2e-05
UniRef50_UPI00015617B8 Cluster: PREDICTED: similar to ral guanin... 52 2e-05
UniRef50_Q55AB0 Cluster: Ras guanine nucleotide exchange factor;... 52 2e-05
UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor ... 52 2e-05
UniRef50_O15211 Cluster: Ral guanine nucleotide dissociation sti... 52 2e-05
UniRef50_UPI00004996A3 Cluster: Ras guanine nucleotide exchange ... 52 3e-05
UniRef50_Q54YQ2 Cluster: Ras guanine nucleotide exchange factor;... 52 3e-05
UniRef50_Q6BNH1 Cluster: Debaryomyces hansenii chromosome E of s... 52 3e-05
UniRef50_Q5KPL7 Cluster: Ras guanyl-nucleotide exchange factor, ... 52 3e-05
UniRef50_UPI000155FBAC Cluster: PREDICTED: similar to ral guanin... 52 4e-05
UniRef50_UPI0000E485ED Cluster: PREDICTED: similar to Ral guanin... 52 4e-05
UniRef50_Q55EC7 Cluster: RasGEF domain-containing protein; n=1; ... 52 4e-05
UniRef50_Q92565 Cluster: Rap guanine nucleotide exchange factor ... 52 4e-05
UniRef50_A7RH05 Cluster: Predicted protein; n=1; Nematostella ve... 51 5e-05
UniRef50_UPI00015B4D6B Cluster: PREDICTED: similar to ral guanin... 51 7e-05
UniRef50_UPI00005A5919 Cluster: PREDICTED: similar to Ral guanin... 51 7e-05
UniRef50_UPI0000ECA662 Cluster: Rap guanine nucleotide exchange ... 51 7e-05
UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange ... 51 7e-05
UniRef50_Q9U4U5 Cluster: Ral guanine nucleotide exchange factor ... 51 7e-05
UniRef50_Q5C2U2 Cluster: SJCHGC07188 protein; n=1; Schistosoma j... 51 7e-05
UniRef50_Q55FD8 Cluster: RasGEF domain-containing protein; n=2; ... 51 7e-05
UniRef50_Q5JUE6 Cluster: Rap guanine nucleotide exchange factor ... 51 7e-05
UniRef50_Q2H8X6 Cluster: Putative uncharacterized protein; n=1; ... 51 7e-05
UniRef50_Q13905 Cluster: Rap guanine nucleotide exchange factor ... 51 7e-05
UniRef50_UPI00015616C9 Cluster: PREDICTED: similar to ral guanin... 50 9e-05
UniRef50_Q16I23 Cluster: Guanine-nucleotide exchange factor c3g;... 50 9e-05
UniRef50_A7S271 Cluster: Predicted protein; n=1; Nematostella ve... 50 9e-05
UniRef50_Q4P4A0 Cluster: Putative uncharacterized protein; n=1; ... 50 9e-05
UniRef50_Q6FVQ6 Cluster: Candida glabrata strain CBS138 chromoso... 50 1e-04
UniRef50_A2Q880 Cluster: Contig An01c0100, complete genome; n=10... 50 1e-04
UniRef50_UPI0000F20A79 Cluster: PREDICTED: hypothetical protein,... 50 2e-04
UniRef50_UPI000156180A Cluster: PREDICTED: similar to Ral guanin... 49 2e-04
UniRef50_UPI0001561381 Cluster: PREDICTED: similar to guanine nu... 49 2e-04
UniRef50_UPI000049846E Cluster: Ras guanine nucleotide exchange ... 49 2e-04
UniRef50_Q7PSV2 Cluster: ENSANGP00000005326; n=1; Anopheles gamb... 49 2e-04
UniRef50_Q2GVZ4 Cluster: Putative uncharacterized protein; n=3; ... 49 2e-04
UniRef50_Q6CY10 Cluster: Guanine nucleotide exchange factor LTE1... 49 2e-04
UniRef50_UPI000156180E Cluster: PREDICTED: similar to ral guanin... 49 3e-04
UniRef50_Q55AH0 Cluster: Ras guanine nucleotide exchange factor;... 49 3e-04
UniRef50_A7S390 Cluster: Predicted protein; n=2; Nematostella ve... 49 3e-04
UniRef50_A2DHX3 Cluster: RasGEF domain containing protein; n=1; ... 49 3e-04
UniRef50_Q75AF6 Cluster: ADL038Wp; n=1; Eremothecium gossypii|Re... 49 3e-04
UniRef50_Q54H48 Cluster: Ras guanine nucleotide exchange factor;... 48 4e-04
UniRef50_Q29IL8 Cluster: GA16131-PA; n=1; Drosophila pseudoobscu... 48 5e-04
UniRef50_Q19770 Cluster: Putative uncharacterized protein; n=2; ... 48 5e-04
UniRef50_A7RT22 Cluster: Predicted protein; n=1; Nematostella ve... 48 5e-04
UniRef50_UPI0000499F54 Cluster: Ras guanine nucleotide exchange ... 48 6e-04
UniRef50_Q6C3H8 Cluster: Similar to CAGL0G06226g Candida glabrat... 48 6e-04
UniRef50_A6SRC2 Cluster: Putative uncharacterized protein; n=1; ... 48 6e-04
UniRef50_O77086 Cluster: Guanine nucleotide-releasing factor 2; ... 48 6e-04
UniRef50_Q4S5W0 Cluster: Chromosome 9 SCAF14729, whole genome sh... 47 8e-04
UniRef50_Q7JTG3 Cluster: Nucleotide exchange factor RasGEF L; n=... 47 8e-04
UniRef50_Q2URQ9 Cluster: Ras1 guanine nucleotide exchange factor... 47 8e-04
UniRef50_Q4T188 Cluster: Chromosome undetermined SCAF10698, whol... 47 0.001
UniRef50_Q9N468 Cluster: Putative uncharacterized protein; n=3; ... 47 0.001
UniRef50_Q6CUP1 Cluster: Similar to ca|CA0382|IPF16030 Candida a... 47 0.001
UniRef50_A3LVY6 Cluster: GDP/GTP exchange factor; n=2; Saccharom... 47 0.001
UniRef50_Q54WL2 Cluster: RasGEF domain-containing protein; n=3; ... 46 0.001
UniRef50_UPI0000D55549 Cluster: PREDICTED: similar to CG3126-PA,... 46 0.002
UniRef50_A7EYT6 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_Q5B8N8 Cluster: Putative uncharacterized protein; n=1; ... 46 0.003
UniRef50_UPI0001561679 Cluster: PREDICTED: similar to ral guanin... 45 0.003
UniRef50_Q54XL4 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_Q5T7U6 Cluster: Ral guanine nucleotide dissociation sti... 45 0.003
UniRef50_Q0TX72 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_UPI000049A05E Cluster: Ras guanine nucleotide exchange ... 45 0.004
UniRef50_A4D140 Cluster: Rap guanine nucleotide exchange factor ... 45 0.004
UniRef50_Q8X027 Cluster: Related to aimless RasGEF; n=2; Neurosp... 45 0.004
UniRef50_Q2GV74 Cluster: Putative uncharacterized protein; n=1; ... 45 0.004
UniRef50_Q54GB4 Cluster: Ras guanine nucleotide exchange factor;... 44 0.006
UniRef50_A2QDU9 Cluster: Contig An02c0260, complete genome; n=4;... 44 0.006
UniRef50_Q59Z59 Cluster: Putative uncharacterized protein LTE1; ... 44 0.008
UniRef50_A5DL36 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_Q9UHV5 Cluster: Rap guanine nucleotide exchange factor-... 43 0.014
UniRef50_A7F2T0 Cluster: Putative uncharacterized protein; n=1; ... 43 0.014
UniRef50_A4R2V9 Cluster: Putative uncharacterized protein; n=1; ... 43 0.014
UniRef50_P26675 Cluster: Protein son of sevenless; n=6; Endopter... 43 0.014
UniRef50_Q07889 Cluster: Son of sevenless homolog 1; n=70; cellu... 43 0.014
UniRef50_UPI00015B5730 Cluster: PREDICTED: similar to guanine-nu... 43 0.018
UniRef50_UPI0000519C35 Cluster: PREDICTED: similar to C3G CG3126... 43 0.018
UniRef50_UPI0000498500 Cluster: Ras guanine nucleotide exchange ... 43 0.018
UniRef50_Q4S7S0 Cluster: Chromosome 18 SCAF14712, whole genome s... 43 0.018
UniRef50_Q54FF3 Cluster: Ras guanine nucleotide exchange factor;... 43 0.018
UniRef50_A5E0J4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.024
UniRef50_UPI000049A5AB Cluster: Ras guanine nucleotide exchange ... 42 0.032
UniRef50_A6RN08 Cluster: Putative uncharacterized protein; n=2; ... 42 0.032
UniRef50_A5DX26 Cluster: Putative uncharacterized protein; n=1; ... 42 0.042
UniRef50_A5DA53 Cluster: Putative uncharacterized protein; n=1; ... 42 0.042
UniRef50_UPI000156177D Cluster: PREDICTED: similar to ral guanin... 41 0.055
UniRef50_UPI000065E6FA Cluster: 1-phosphatidylinositol-4,5-bisph... 41 0.055
UniRef50_Q873I0 Cluster: Related to LTE1 protein; n=2; Neurospor... 41 0.055
UniRef50_Q6FT12 Cluster: Guanine nucleotide exchange factor LTE1... 41 0.055
UniRef50_Q4RG56 Cluster: Chromosome 2 SCAF15106, whole genome sh... 41 0.073
UniRef50_A7SA05 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.073
UniRef50_A2F534 Cluster: RasGEF domain containing protein; n=1; ... 41 0.073
UniRef50_Q8TDF6 Cluster: RAS guanyl-releasing protein 4; n=32; T... 41 0.073
UniRef50_Q8N437 Cluster: RASGEF1B protein; n=8; Euteleostomi|Rep... 41 0.073
UniRef50_Q6UNM9 Cluster: LTE1-like protein; n=1; Epichloe festuc... 41 0.073
UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange ... 40 0.096
UniRef50_A2RRV5 Cluster: Histone H2A; n=2; Danio rerio|Rep: Hist... 40 0.13
UniRef50_Q550U8 Cluster: Ras guanine nucleotide exchange factor;... 40 0.13
UniRef50_Q9HF75 Cluster: GTPase-activating protein BEM2; n=1; Er... 40 0.13
UniRef50_UPI0000499791 Cluster: Ras guanine nucleotide exchange ... 40 0.17
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 40 0.17
UniRef50_Q4PFF2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.17
UniRef50_A5E683 Cluster: Putative uncharacterized protein; n=1; ... 40 0.17
UniRef50_UPI00015B5A66 Cluster: PREDICTED: similar to phospholip... 39 0.22
UniRef50_Q5RH52 Cluster: Novel RasGEF domain containing protein;... 39 0.22
UniRef50_Q4T1D4 Cluster: Chromosome undetermined SCAF10661, whol... 39 0.22
UniRef50_Q9GQC2 Cluster: Ras guanine nucleotide exchange factor ... 39 0.22
UniRef50_UPI0000498D55 Cluster: Ras guanine nucleotide exchange ... 39 0.29
UniRef50_Q54L90 Cluster: RasGEF domain-containing protein; n=1; ... 39 0.29
UniRef50_A2DUN7 Cluster: RasGEF domain containing protein; n=1; ... 39 0.29
UniRef50_A3LSD7 Cluster: Bud-emergence protein; n=2; Saccharomyc... 39 0.29
UniRef50_A2DMC1 Cluster: RasGEF domain containing protein; n=1; ... 38 0.39
UniRef50_Q5AGW7 Cluster: Putative uncharacterized protein BEM2; ... 38 0.39
UniRef50_P34578 Cluster: Uncharacterized protein T20G5.5; n=2; C... 38 0.39
UniRef50_UPI000155BE40 Cluster: PREDICTED: similar to ras guanyl... 38 0.68
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 38 0.68
UniRef50_UPI00015603B4 Cluster: PREDICTED: similar to ral guanin... 37 0.90
UniRef50_UPI00005A5D6B Cluster: PREDICTED: similar to Ral guanin... 37 0.90
UniRef50_UPI000049A353 Cluster: hypothetical protein 66.t00031; ... 37 0.90
UniRef50_UPI0000499BEE Cluster: Ras guanine nucleotide exchange ... 37 0.90
UniRef50_A0BXA6 Cluster: Chromosome undetermined scaffold_134, w... 37 1.2
UniRef50_Q6BZP3 Cluster: Yarrowia lipolytica chromosome F of str... 37 1.2
UniRef50_Q4P292 Cluster: Putative uncharacterized protein; n=1; ... 37 1.2
UniRef50_Q9P212 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 37 1.2
UniRef50_UPI000049A3AF Cluster: Ras guanine nucleotide exchange ... 36 1.6
UniRef50_UPI000023DED7 Cluster: hypothetical protein FG06583.1; ... 36 1.6
UniRef50_A4Y0Y3 Cluster: Tetratricopeptide TPR_2 repeat protein ... 36 2.1
UniRef50_A2U669 Cluster: Conserved hypothetical membrane spannin... 36 2.1
UniRef50_Q4E1N0 Cluster: Guanine nucleotide releasing protein, p... 36 2.1
UniRef50_A2EWA8 Cluster: RasGEF domain containing protein; n=1; ... 36 2.1
UniRef50_A7TGB0 Cluster: Putative uncharacterized protein; n=1; ... 36 2.1
UniRef50_Q5ZQY4 Cluster: Portal protein; n=2; root|Rep: Portal p... 35 3.6
UniRef50_UPI0000499FDF Cluster: Ras guanine nucleotide exchange ... 35 4.8
UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1; ... 35 4.8
UniRef50_Q0LJK2 Cluster: Penicillin-binding protein 1A; n=1; Her... 35 4.8
UniRef50_Q4S6H2 Cluster: Chromosome 10 SCAF14728, whole genome s... 34 6.3
UniRef50_A6Q940 Cluster: Putative uncharacterized protein; n=1; ... 34 6.3
UniRef50_A3WLS4 Cluster: Hypothetical FOG: GGDEF domain protein;... 34 6.3
UniRef50_Q1E205 Cluster: Putative uncharacterized protein; n=1; ... 34 6.3
UniRef50_A5WF04 Cluster: Putative uncharacterized protein; n=1; ... 34 8.4
UniRef50_A3HPF1 Cluster: Putative uncharacterized protein; n=1; ... 34 8.4
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 34 8.4
UniRef50_Q6FQG1 Cluster: Similar to sp|P39960 Saccharomyces cere... 34 8.4
>UniRef50_Q28EC1 Cluster: Ras-GEF domain-containing family member
1B; n=5; Coelomata|Rep: Ras-GEF domain-containing family
member 1B - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 472
Score = 198 bits (482), Expect = 3e-49
Identities = 109/245 (44%), Positives = 148/245 (60%), Gaps = 19/245 (7%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
++++L +WT FPYDFRD+R+M ++ R E R + ++ L+ KL +L Q
Sbjct: 110 ILQLLTEWTETFPYDFRDERMMRNLKDTAHRITNGD-EMYRKNVQQIIQNLIRKLASLTQ 168
Query: 169 YEESLVDI--------TQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEF 220
YEE + I T + + Q Q DI+T+ P +A QLT +EL RLS++GPEEF
Sbjct: 169 YEELITKINAQSTDRMTVLKTKPQSIQRDIITVCSDPYTVAQQLTHIELERLSYIGPEEF 228
Query: 221 VQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYR 280
VQ F P + C + D K RNLEAY +WFNRLSYLVAT+I VK K+R
Sbjct: 229 VQAFVQKDPLDNNENC-------YSDRKKPRNLEAYVEWFNRLSYLVATEICMPVKKKHR 281
Query: 281 ARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCV 340
AR+IE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++ + LE +
Sbjct: 282 ARMIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTA---KFDILEHQM 338
Query: 341 EPTGN 345
+P+ N
Sbjct: 339 DPSSN 343
Score = 43.2 bits (97), Expect = 0.014
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 344 GNHARLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLT 403
G +RL VNFEK L+K VS + +++ + Y+ P +
Sbjct: 386 GCTSRLPNGHVNFEKFWELAKQVSEFMTWKQVECP-------FEKDRKILHYVLTAPIFS 438
Query: 404 EPALELVSFEREPPVDHLEKERLKRLRGS 432
E AL L S+E E P +H+EK+R K LR +
Sbjct: 439 EDALYLASYESEGPENHIEKDRWKTLRSA 467
>UniRef50_Q4SDT4 Cluster: Chromosome 1 SCAF14632, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
SCAF14632, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 504
Score = 180 bits (438), Expect = 7e-44
Identities = 109/248 (43%), Positives = 146/248 (58%), Gaps = 21/248 (8%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
++++L++WT FP DFRD++++ + I R AA E+ ++ L+KL +L + Q
Sbjct: 122 ILQLLKEWTETFPSDFRDEKMVGHLEDIIHRIAACD-EAYWKTLNQVLQKLNQRLVLMSQ 180
Query: 169 YEESLVDIT-QVSSL-DQLS---------QGDILTLGLTPVELANQLTIVELHRLSFVGP 217
EES + ++ SS+ D+L Q DIL++ P LA QLT VEL LS +GP
Sbjct: 181 GEESSLKVSVNASSISDKLVAFKTKPPPIQKDILSICNDPYTLAQQLTHVELEHLSHIGP 240
Query: 218 EEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKS 277
EEFVQ F P T C + K + NLEAY WFNRL YLVAT+I K
Sbjct: 241 EEFVQAFVQKDPLDGTQPCFSD------QKKKSSNLEAYVRWFNRLCYLVATEICMPAKK 294
Query: 278 KYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLE 337
K RA+VIE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW + + LE
Sbjct: 295 KQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWGKAKTA---KFFILE 351
Query: 338 LCVEPTGN 345
++PTGN
Sbjct: 352 HQMDPTGN 359
Score = 39.1 bits (87), Expect = 0.22
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L++ V + +++ + YL+ P +E L
Sbjct: 429 RLPNGHVNFEKFVELARQVGEFMTWKQVECP-------FEEDRAILHYLHTAPVFSEDGL 481
Query: 408 ELVSFEREPPVDHLEKERLKRLR 430
L S+E E P + +EK+R K LR
Sbjct: 482 YLASYESESPENQVEKDRWKALR 504
>UniRef50_Q8N431 Cluster: Ras-GEF domain-containing family member
1C; n=57; Euteleostomi|Rep: Ras-GEF domain-containing
family member 1C - Homo sapiens (Human)
Length = 466
Score = 171 bits (417), Expect = 2e-41
Identities = 107/241 (44%), Positives = 135/241 (56%), Gaps = 17/241 (7%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
L+++L +WT FP DF+++ + ++ + R A E+ R M L+ L KL AL Q
Sbjct: 110 LLQLLAEWTETFPRDFQEESTIGHLKDVVGRIAPCD-EAYRKRMHQLLQALHQKLAALRQ 168
Query: 169 YEESLVDITQVSSLDQLSQGDILT--LGLT--PVELANQLTIVELHRLSFVGPEEFVQTF 224
E LV + S I LG+ P LA QLT VEL RL +GPEEFVQ F
Sbjct: 169 GPEGLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAF 228
Query: 225 APIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVI 284
P ST C + T NLEAY WFNRL YLVAT+I K K RA+VI
Sbjct: 229 VNKDPLASTKPCFSDK---------TSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVI 279
Query: 285 EQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTG 344
E ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++ + LE ++PTG
Sbjct: 280 EFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVRTA---KFFILEHQMDPTG 336
Query: 345 N 345
N
Sbjct: 337 N 337
Score = 40.7 bits (91), Expect = 0.073
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L+K V + +++ + YL P +E L
Sbjct: 384 RLPNGHVNFEKFLELAKQVGEFITWKQVECP-------FEQDASITHYLYTAPIFSEDGL 436
Query: 408 ELVSFEREPPVDHLEKERLKRLRGS 432
L S+E E P + EKER K LR S
Sbjct: 437 YLASYESESPENQTEKERWKALRSS 461
>UniRef50_A7S619 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 417
Score = 162 bits (394), Expect = 1e-38
Identities = 98/261 (37%), Positives = 148/261 (56%), Gaps = 17/261 (6%)
Query: 93 AEVKDLVEKELNDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESV--RV 150
++VK L ++ L+++L +W F DFRD+ +M + IT C S R
Sbjct: 52 SQVKILSDETKKLAFNLLQLLSEWAETFTNDFRDEVMMMHFKDITTYCGTLSAVSKEHRK 111
Query: 151 EMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQGD----ILTLGLTPVELANQLTI 206
+ T + L K +L++Y+E L T +L+ +L + +P +A QL++
Sbjct: 112 VVGDTTQSLFKKFASLDKYDEVLSRATAAVEDRKLTTSSHYKSVLEVCSSPTIMAQQLSL 171
Query: 207 VELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYL 266
+EL RL+ +GPEEFVQTF P + + K+++S K T +LEAY +WFNRL YL
Sbjct: 172 IELERLANIGPEEFVQTFIP----RDEADFKSTLSY----IKRTSSLEAYVEWFNRLGYL 223
Query: 267 VATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
VAT+I G K RA+VI+ ++ +C++ GNFNS MAII+ +NMSPV RLKKTWS+
Sbjct: 224 VATEICLGHNKKVRAKVIDYFIEVATDCYDRGNFNSAMAIIAGINMSPVARLKKTWSK-- 281
Query: 327 AVCGQQLRQLELCVEPTGNHA 347
V ++ +LE + P N A
Sbjct: 282 -VKNRKFDRLEREMNPASNFA 301
>UniRef50_Q8N9B8 Cluster: Ras-GEF domain-containing family member
1A; n=21; Amniota|Rep: Ras-GEF domain-containing family
member 1A - Homo sapiens (Human)
Length = 481
Score = 155 bits (376), Expect = 2e-36
Identities = 95/248 (38%), Positives = 149/248 (60%), Gaps = 23/248 (9%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAA--EHMESVRVEMSTTLEKLLDKLTAL 166
+V++L++WT FPYDF+D++ MA +++IT R E +V+ ++ + LL L A
Sbjct: 117 IVQLLKEWTEAFPYDFQDEKAMAELKAITHRVTQCDEENGTVKKAIAQMTQSLLLSLAAR 176
Query: 167 EQYEESLVDITQVSSLDQ---------LSQGDILTLGLTPVELANQLTIVELHRLSFVGP 217
Q +E L + + ++D+ +Q DIL + P+ LA QLT +EL R+S + P
Sbjct: 177 SQLQE-LREKLRPPAVDKGPILKTKPPAAQKDILGVCCDPLVLAQQLTHIELDRVSSIYP 235
Query: 218 EEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKS 277
E+ +Q + + + C+ + TK T +LEAY +WFN LS LVAT++ + VK
Sbjct: 236 EDLMQIVSHMDSLDN-HRCRGDL------TK-TYSLEAYDNWFNCLSMLVATEVCRVVKK 287
Query: 278 KYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLE 337
K+R R++E ++ RECFN+GNFNS+MAIIS +N+SPV RLKKTWS+ + LE
Sbjct: 288 KHRTRMLEFFIDVARECFNIGNFNSMMAIISGMNLSPVARLKKTWSKVKTA---KFDVLE 344
Query: 338 LCVEPTGN 345
++P+ N
Sbjct: 345 HHMDPSSN 352
Score = 35.1 bits (77), Expect = 3.6
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 395 YLNDRPTLTEPALELVSFEREPPVDHLEKERLKRLR 430
YL P +E AL + SFE E P +H+EK+ K LR
Sbjct: 439 YLLTAPIYSEEALFVASFESEGPENHMEKDSWKTLR 474
>UniRef50_Q8SYL9 Cluster: RE54096p; n=4; Sophophora|Rep: RE54096p -
Drosophila melanogaster (Fruit fly)
Length = 691
Score = 150 bits (364), Expect = 6e-35
Identities = 78/154 (50%), Positives = 100/154 (64%), Gaps = 11/154 (7%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQS--------TSACKTSISLHHIDTKCTR 251
LA+QLT +EL RLS +GPEEFVQ FA + Q+ S C D K TR
Sbjct: 389 LAHQLTAIELERLSHIGPEEFVQAFAKDYQQQAKDGSREANNSKCSGGGGGSLNDMKKTR 448
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NLE+Y WFNRLSYL A++I+K K K R R+IE W+ T RECFN+GNFNSLMAII+ LN
Sbjct: 449 NLESYVQWFNRLSYLTASEIVKYPKKKQRVRIIEYWIETARECFNIGNFNSLMAIIAGLN 508
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
++P+ RLKKTW++ + + LE ++PT N
Sbjct: 509 LAPIGRLKKTWAKVQSA---KFSVLEHQMDPTSN 539
Score = 63.7 bits (148), Expect = 9e-09
Identities = 31/78 (39%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Query: 110 VRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQY 169
+R+L +W +FPYDFRD+R+M VR + ++C S+ ++S L+ L+ +LT LEQY
Sbjct: 235 IRLLSEWIEIFPYDFRDERLMQQVRILARKCVYID-NSLGKQVSRILQLLVSRLTTLEQY 293
Query: 170 EESLVDITQVSSLDQLSQ 187
EE L I+ + Q Q
Sbjct: 294 EEFLQTISSEEAQSQQQQ 311
Score = 42.7 bits (96), Expect = 0.018
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL N +NFEKC+ L+K V +++ V YL + L E L
Sbjct: 586 RLPNNHINFEKCSQLAKQVMEFNEWKKVNCP-------FERLPNVIAYLQNSAVLNENTL 638
Query: 408 ELVSFEREPPVDHLEKERLKRLRG 431
+ SFE EPP + EK+R + ++G
Sbjct: 639 SMASFECEPPENTEEKDRYRTVKG 662
>UniRef50_Q7QFQ1 Cluster: ENSANGP00000007336; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000007336 - Anopheles gambiae
str. PEST
Length = 277
Score = 149 bits (361), Expect = 1e-34
Identities = 94/220 (42%), Positives = 121/220 (55%), Gaps = 25/220 (11%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
L +L W + FPYDFRD+R+M LVRS T+ +H +S L +L +L LE+
Sbjct: 66 LPHLLAAWMNDFPYDFRDERMMRLVRSFTE----QHT------LSRALRRLAHRLAKLER 115
Query: 169 YEES---LVDITQVSSLDQLSQGDILT--LGLTPVELANQLTIVELHRLSFVGPEEFVQT 223
YE L + LD L +PV +AN LT +E R SF+G EEF
Sbjct: 116 YEVEKGPLGPPAKGGGLDDWKTAPALVELASGSPVLMANTLTAIEAERFSFIGLEEFF-- 173
Query: 224 FAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARV 283
PP SA S + NL AY W+NRL+Y+VATDIL+ + ++RAR
Sbjct: 174 -----PPSGQSA---GASCYRGTGPTGSNLLAYVQWYNRLTYVVATDILRSPRKRHRARA 225
Query: 284 IEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
+E W+ TGRECFN GNFNSLMAII+ L P+ RLKKT S
Sbjct: 226 VEFWIETGRECFNRGNFNSLMAIIATLTGGPIGRLKKTVS 265
>UniRef50_Q21758 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 461
Score = 117 bits (281), Expect = 7e-25
Identities = 78/246 (31%), Positives = 131/246 (53%), Gaps = 24/246 (9%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHM-ESVRVEMSTTLEKLLDKLTALE 167
++R+ +W + PYDF+ + + + + + CA + + E+ +TL L+KL +
Sbjct: 106 ILRLCSEWATNIPYDFKTEYMRTRLNELLRLCAVDKTYQQKTTELQSTLRSSLNKL---D 162
Query: 168 QYEESLVDITQVSS--LDQLSQGDILTLGLTPV-----ELANQLTIVELHRLSFVGPEEF 220
+YE+++ ++ + S + Q D +T GL + +A QLT +E+ R S VG +E
Sbjct: 163 RYEKAVANLQKALSENTNLPEQSDSMT-GLFVLCNDAKTVAQQLTHIEMERFSMVGVDEI 221
Query: 221 VQTFAPIHPPQSTSACKTSISLHHIDTKCT-RNLEAYADWFNRLSYLVATDILKGVKSKY 279
VQ+ A P S I H + + T ++ Y +WFNRLS A ++LK K +
Sbjct: 222 VQSLAS--DPLS------EIGRHSKNKEGTISSISFYIEWFNRLSAFAAIEVLKQTKKRN 273
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELC 339
R V E + +EC +GNFNS+MAI++ L++ V RLKKTW R +L L+
Sbjct: 274 RVAVFEFMIDIAKECCEIGNFNSMMAIVAGLSLPAVSRLKKTWCRVEKA---KLEILQHQ 330
Query: 340 VEPTGN 345
++P+GN
Sbjct: 331 LDPSGN 336
>UniRef50_Q95S44 Cluster: GM09415p; n=4; Sophophora|Rep: GM09415p -
Drosophila melanogaster (Fruit fly)
Length = 709
Score = 116 bits (279), Expect = 1e-24
Identities = 79/259 (30%), Positives = 130/259 (50%), Gaps = 18/259 (6%)
Query: 98 LVEKELNDMIALVRVLRQWTSMFPYDFRDDRVMA-LVRSITQRCAAEHMESVRVEMSTTL 156
++ K N+ ++R+L +W P DF + ++ L + A ++ + ++
Sbjct: 328 IIAKIDNEEENVLRLLNEWLDTCPGDFSHELLLQELENKRNVKGLAAFLDGIPQALAQKD 387
Query: 157 EKLLDKLTALEQYEESLVDITQVSSLDQLSQ--------GDILTLGLTPVELANQLTIVE 208
E +L L + S + + SS+ L + ++L + ELA+QL +E
Sbjct: 388 ENGRSQLNNLLTKQSSASSLGRQSSIKSLKRFAANVYKTDNVLNNCSSAFELAHQLYAIE 447
Query: 209 LHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN--LEAYADWFNRLSYL 266
LS + EEFV+ I C + + + C +++Y WFN+LSYL
Sbjct: 448 YAYLSQIRLEEFVE----ILEKDELKTCISQTKAGTLGSNCISQVTIDSYVQWFNQLSYL 503
Query: 267 VATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
AT+ILK K RA++I+ WV T ECFN GNFNSLMAI++ALN++ + RLKKTW++
Sbjct: 504 TATEILKLGKKSQRAQMIDFWVETALECFNTGNFNSLMAILTALNLTAIARLKKTWAKVQ 563
Query: 327 AVCGQQLRQLELCVEPTGN 345
+ LE ++P+ N
Sbjct: 564 TT---KFEGLEHQMDPSSN 579
>UniRef50_Q9VQM8 Cluster: CG15405-PA; n=4; Diptera|Rep: CG15405-PA -
Drosophila melanogaster (Fruit fly)
Length = 471
Score = 113 bits (271), Expect = 1e-23
Identities = 76/219 (34%), Positives = 112/219 (51%), Gaps = 10/219 (4%)
Query: 108 ALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALE 167
+LV +L +WT FPYD+RD+R+M+ V+ I RC+ H+E+ +S TL LL +LT LE
Sbjct: 248 SLVSLLAEWTMKFPYDYRDERMMSHVKHIVARCSNSHLEAA---VSQTLSALLKRLTDLE 304
Query: 168 QYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPI 227
++E D+ + D+ L T + A + VE +G EEF+Q + I
Sbjct: 305 RHE---ADLRACQTNDKSGPETPLNCP-TATQYAQIVCRVEKKLAKHIGGEEFLQCSSMI 360
Query: 228 HPPQSTSACKTSIS---LHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVI 284
+ + S S D K T NLE Y DW RL V +IL+ V + R+R +
Sbjct: 361 LLDKQKKWDQPSTSGAPPGAQDPKKTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTV 420
Query: 285 EQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
E W + C +GN+NS AI+ +L + RLK T S
Sbjct: 421 ELWSGVAQYCLLVGNYNSATAILESLESPAIARLKITVS 459
>UniRef50_A4RFZ9 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1295
Score = 80.2 bits (189), Expect = 1e-13
Identities = 40/100 (40%), Positives = 63/100 (63%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N++A + + N LS LV+ IL + K RA V++QW+ +C +L N+++LMAII +LN
Sbjct: 1016 NVKAMSTFSNDLSSLVSDTILHYNEVKKRAAVLKQWIKIAHQCLDLNNYDALMAIICSLN 1075
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSG 351
S + RL++TW S + L+QL+ VEP+ N+ L G
Sbjct: 1076 SSTITRLRRTWEAVSPRRRELLKQLQAIVEPSQNNKVLRG 1115
>UniRef50_Q4WNQ3 Cluster: Ras guanine-nucleotide exchange protein,
putative; n=5; Trichocomaceae|Rep: Ras guanine-nucleotide
exchange protein, putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 1167
Score = 79.0 bits (186), Expect = 2e-13
Identities = 61/174 (35%), Positives = 86/174 (49%), Gaps = 19/174 (10%)
Query: 178 QVSSLDQLSQGD--ILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSA 235
+V+ L Q G+ I L P+ELA QLTI E + PEE + +T
Sbjct: 861 EVNLLKQWKNGEAAISILDFDPLELARQLTIKESRIFCAILPEELL----------ATEW 910
Query: 236 CKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECF 295
K S SL N+ A + L++LVA IL+ + K RA +I+QWV +C
Sbjct: 911 MKKSASL-------AVNVRAMSTLSTDLAHLVADSILQLEEPKKRAAIIKQWVKIANKCL 963
Query: 296 NLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
L N+++LMAII +LN S + RLK+TW S L L V+ + N+A L
Sbjct: 964 ELNNYDTLMAIICSLNSSMISRLKRTWEVVSQKTKATLETLRGIVDVSRNYAVL 1017
>UniRef50_A1CGW5 Cluster: Ras guanine-nucleotide exchange protein,
putative; n=3; Eurotiomycetidae|Rep: Ras
guanine-nucleotide exchange protein, putative -
Aspergillus clavatus
Length = 1187
Score = 76.6 bits (180), Expect = 1e-12
Identities = 59/174 (33%), Positives = 85/174 (48%), Gaps = 19/174 (10%)
Query: 178 QVSSLDQLSQGD--ILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSA 235
+V+ L Q GD + L P+ELA QLTI E + PEE + +T
Sbjct: 879 EVNLLKQWKNGDGALSILDFDPMELARQLTIKESRIFCTILPEELL----------ATEW 928
Query: 236 CKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECF 295
K + SL N+ A + L++LVA IL+ + K RA +I+ WV +C
Sbjct: 929 MKKTASL-------AVNVRAMSTLSTDLAHLVADSILQLEEPKKRAAIIKHWVKIANKCL 981
Query: 296 NLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
L N++SLMAII +LN S + RL++TW S L L V+ + N+A L
Sbjct: 982 ELNNYDSLMAIICSLNSSMISRLRRTWEVVSHKTKTTLEMLRGIVDVSRNYAVL 1035
>UniRef50_Q23867 Cluster: Aimless RasGEF; n=3; Dictyostelium
discoideum|Rep: Aimless RasGEF - Dictyostelium
discoideum (Slime mold)
Length = 605
Score = 76.2 bits (179), Expect = 2e-12
Identities = 65/243 (26%), Positives = 114/243 (46%), Gaps = 19/243 (7%)
Query: 104 NDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKL 163
N I ++ VL+ W + DF DD+++A++R+ + + ++ +L K+++KL
Sbjct: 262 NIQIRVINVLKGWVDNYYSDF-DDKLIAMLRTFIDQIQIKFPAPASA-VNKSLTKMVEKL 319
Query: 164 TALEQYEESLVDITQVSSLDQ-LSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQ 222
+ + + + T + + + ++ + E+A QLT++E + P E +
Sbjct: 320 SPVNDSKHIFNEKTPEPMVPKNIFSNNLSIYDIDEEEIARQLTLIEFEIYRNIKPPELLN 379
Query: 223 TFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRAR 282
QS + KT + N+ D FN +S VAT I++ K K RAR
Sbjct: 380 --------QSWN--KTKLKSR------APNVLKMIDRFNSVSMWVATMIIQTTKVKARAR 423
Query: 283 VIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEP 342
++ +++ NL N+NSLMAII+ LN S V RLK T SA + LE +
Sbjct: 424 MMTRFIKIADHLKNLNNYNSLMAIIAGLNFSSVYRLKYTREELSAQTMRTYSDLEKIMNS 483
Query: 343 TGN 345
G+
Sbjct: 484 EGS 486
>UniRef50_Q0UTD8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1210
Score = 74.5 bits (175), Expect = 5e-12
Identities = 55/157 (35%), Positives = 78/157 (49%), Gaps = 17/157 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L P+ELA Q TI+E + EE + + K S D+K N
Sbjct: 917 LDFDPLELARQFTIIESRLFCSIQSEELL----------ALEWTKKS------DSKAV-N 959
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
++A + L+ LVA IL +K RA +I+QWV +C L N++SLMAII +LN
Sbjct: 960 VKAMSTLSTDLANLVADTILHLEDAKKRAAIIKQWVKIAAKCLELNNYDSLMAIICSLNS 1019
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
S VMRLK+TW S +L +L+ + N+A L
Sbjct: 1020 SMVMRLKRTWELVSTKTKTRLEELKAITDVGRNYAVL 1056
>UniRef50_UPI00015A6BDA Cluster: UPI00015A6BDA related cluster; n=1;
Danio rerio|Rep: UPI00015A6BDA UniRef100 entry - Danio
rerio
Length = 725
Score = 73.3 bits (172), Expect = 1e-11
Identities = 50/198 (25%), Positives = 93/198 (46%), Gaps = 22/198 (11%)
Query: 156 LEKLLDKLTALEQYE-----ESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELH 210
L KL D++ +Y E+ + V +L+ + + L L+ +E+ANQL+
Sbjct: 47 LSKLADRIQLSARYYLKSNMETETLCSDVEALEMQRESVVPLLSLSSMEIANQLSARNYL 106
Query: 211 RLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATD 270
S + P +++ +HP + + NL + N+ ++ VAT+
Sbjct: 107 LFSCIEPTDYINDLFKLHPQEPPT-----------------NLRNFEGLVNQETFWVATE 149
Query: 271 ILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCG 330
I++ R ++I+ ++ C + NFNS+ AIIS N++PV RL+ TW R
Sbjct: 150 IVQETNLAKRVKIIKHFIKIALHCRDCKNFNSMFAIISGFNLAPVSRLRSTWERLPGKYE 209
Query: 331 QQLRQLELCVEPTGNHAR 348
+ L +L+ +P+ N A+
Sbjct: 210 KLLAELQDVFDPSRNMAK 227
>UniRef50_Q6C637 Cluster: YlCDC25 protein; n=2; Yarrowia
lipolytica|Rep: YlCDC25 protein - Yarrowia lipolytica
(Candida lipolytica)
Length = 1250
Score = 72.5 bits (170), Expect = 2e-11
Identities = 36/86 (41%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 261 NRLSYLVATDILK-GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
N+LS LV IL+ G+ +K R +++QW+ G +C LGNFNSL+ I+SAL +MRL+
Sbjct: 1049 NKLSALVGDSILRHGLNAKQRKNILKQWIRIGDKCLELGNFNSLLTIVSALQSVSIMRLR 1108
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN 345
KTW S L+ V P N
Sbjct: 1109 KTWEMLSPRYQTLFASLKAIVLPEKN 1134
>UniRef50_UPI0000498DA7 Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 677
Score = 70.9 bits (166), Expect = 6e-11
Identities = 69/255 (27%), Positives = 113/255 (44%), Gaps = 32/255 (12%)
Query: 94 EVKDLVEKELNDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMS 153
++KD+ K + + ++ +L +W S FP+DF D AL+ + Q E
Sbjct: 349 QIKDVQHKTI---LKILFMLSKWMSSFPHDFMDGGKEALLPLLDQFIKQN-------END 398
Query: 154 TTLEKL-LDKLTALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVE-LANQLTIVELHR 211
T L+K L+K ++ + L T LD ++ T+ P E A QLT+ E
Sbjct: 399 TLLKKTALNKQMMIQSASQKL---TIEEKLDIVNVQQEYTISTLPTEQFAQQLTLYEYEL 455
Query: 212 LSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDI 271
+ +E + T + KT S NL A D FN ++ V + I
Sbjct: 456 FKSIEAKEMLGN-------AWTKSDKTERS---------PNLCALIDHFNSITNWVISTI 499
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQ 331
+ K RA +I++++ G E L N+N + + S LN +PV RLK TW +
Sbjct: 500 VDESNIKQRATIIKKFISIGEEMLRLNNYNGVFEMFSGLNSTPVGRLKLTWEEVGNF-SK 558
Query: 332 QLRQLELCVEPTGNH 346
+++ LE PTG++
Sbjct: 559 KMKALERVTIPTGSY 573
>UniRef50_A7SLX0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 626
Score = 70.5 bits (165), Expect = 8e-11
Identities = 33/94 (35%), Positives = 58/94 (61%)
Query: 258 DWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
++FNR++ LVA++IL ++ RARV+ + + +C LGN+NSL A+++ L +P+ R
Sbjct: 167 EFFNRIAMLVASEILAEETTQARARVVSKVIQIADKCRLLGNYNSLKALMAGLQSAPIYR 226
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSG 351
LK+TW S+ ++ R L + + + N A G
Sbjct: 227 LKQTWKEVSSKRRKKFRHLSIIMGESDNFALYRG 260
>UniRef50_Q4RS43 Cluster: Chromosome 7 SCAF15001, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 7 SCAF15001, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1578
Score = 69.7 bits (163), Expect = 1e-10
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 7/194 (3%)
Query: 157 EKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVG 216
E L A + ES + + Q+S+++ +Q L + EL + E F
Sbjct: 736 ETLCSDEDAQDLLRESQISLLQLSTMEVAAQ-----LSMRDFELFRNIESTEYGAFGFSD 790
Query: 217 PEEFVQTFA-PIHPPQSTSACKTSISLHHIDTKC-TRNLEAYADWFNRLSYLVATDILKG 274
V + ++ C+ L +DT +RNL+ + + N+ ++ VA++ILK
Sbjct: 791 LFALVNDIVFALELNKNPYCCRYLDDLFKLDTSIGSRNLKQFEEVINQETFWVASEILKE 850
Query: 275 VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLR 334
+ R + I+ ++ C NFNS+ AIIS LN++PV RL+ +W + + +
Sbjct: 851 PNTLKRMKTIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRSSWEKLPSKYEKLFG 910
Query: 335 QLELCVEPTGNHAR 348
L+ +P+ N A+
Sbjct: 911 DLQDVFDPSRNMAK 924
>UniRef50_Q54F62 Cluster: RasGEF domain-containing protein; n=2;
Dictyostelium discoideum|Rep: RasGEF domain-containing
protein - Dictyostelium discoideum AX4
Length = 2631
Score = 69.7 bits (163), Expect = 1e-10
Identities = 42/153 (27%), Positives = 72/153 (47%), Gaps = 5/153 (3%)
Query: 197 PVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAY 256
P +A Q T +EL L + P E + + P + ++ Y
Sbjct: 1709 PELIARQYTFLELKYLQNIHPRELLGFSVGLVMPNENEKDPEKWRQSNFP-----HIYDY 1763
Query: 257 ADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVM 316
WFN+++ LV+T+IL+ K RA +IE+++ E +L NFN +M ++S+L+ P+
Sbjct: 1764 FRWFNKMTMLVSTEILRQRDIKQRASIIEKYISIALEYLSLWNFNGIMQVLSSLHSEPIS 1823
Query: 317 RLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
RL TW++ S +L + P N+ L
Sbjct: 1824 RLSATWAKVSQRSMDCFYELSRLMLPESNYLPL 1856
>UniRef50_Q55CK1 Cluster: Ras guanine nucleotide exchange factor;
n=2; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor - Dictyostelium discoideum
AX4
Length = 1037
Score = 68.9 bits (161), Expect = 2e-10
Identities = 55/223 (24%), Positives = 100/223 (44%), Gaps = 23/223 (10%)
Query: 107 IALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLL--DKLT 164
+ + V++ W YDF +D+ + L + H+ ++ L++LL D++
Sbjct: 640 LKITNVIKSWVDKHYYDFSEDKQLTLK---LDQFITNHIMFDMDKIGFNLKRLLTNDRVV 696
Query: 165 ALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTF 224
+ + + T + + + +I L P E+A QLT+ E +G +E
Sbjct: 697 PVPTFTQG--PPTPIPPKMKSNGSEINFKDLDPTEIARQLTLYESDLFRKIGAKE----- 749
Query: 225 APIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVI 284
C + N+ ++ FN++S VAT+I++ K K R I
Sbjct: 750 -----------CLGQAWNKDGKEENAPNIVSFIKRFNQVSSWVATEIVRQEKLKDRVSYI 798
Query: 285 EQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSA 327
+++++ +EC L NFN+ M I+S L S V RL+KTW R +
Sbjct: 799 KRFILVAQECRKLNNFNATMEILSGLQNSSVYRLRKTWERVES 841
>UniRef50_Q8IZJ4 Cluster: Ral-GDS-related protein; n=32;
Catarrhini|Rep: Ral-GDS-related protein - Homo sapiens
(Human)
Length = 473
Score = 68.9 bits (161), Expect = 2e-10
Identities = 34/86 (39%), Positives = 55/86 (63%), Gaps = 4/86 (4%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRL+ + T L ++++ RARV+E W+ REC +L NF+S+ I+SAL +P+ +
Sbjct: 270 FNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQ 329
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPT 343
L KTW+ S+ ++L+ ELC + T
Sbjct: 330 LHKTWAGVSSKSMKELK--ELCKKDT 353
>UniRef50_UPI00006A087A Cluster: Ral guanine nucleotide dissociation
stimulator-like 2 (RalGDS-like factor) (RAS-associated
protein RAB2L).; n=2; Xenopus tropicalis|Rep: Ral
guanine nucleotide dissociation stimulator-like 2
(RalGDS-like factor) (RAS-associated protein RAB2L). -
Xenopus tropicalis
Length = 471
Score = 67.3 bits (157), Expect = 7e-10
Identities = 36/92 (39%), Positives = 55/92 (59%), Gaps = 2/92 (2%)
Query: 260 FNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRLS V + ++ +K + RAR+IE+WV EC +L NF+S+ AII+AL + V R
Sbjct: 246 FNRLSGAVTSSCVRDPQLKPQQRARIIEKWVRVAEECRSLRNFSSVYAIITALQSTAVHR 305
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
LKK W+ TS + +++ N+AR+
Sbjct: 306 LKKVWAETSREILRSYQEMREVFCEKDNYARM 337
>UniRef50_Q5K6X7 Cluster: Cell division control protein 25, putative;
n=2; Filobasidiella neoformans|Rep: Cell division control
protein 25, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 1368
Score = 67.3 bits (157), Expect = 7e-10
Identities = 70/228 (30%), Positives = 104/228 (45%), Gaps = 26/228 (11%)
Query: 107 IALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTAL 166
+ +V LRQW DD V++ V + R E ++ MS L +L+ K
Sbjct: 984 LRVVNALRQWLEKHFIRATDDAVLSKVEELALRMPEEDGKAEL--MSKQLLQLVAKRRQS 1041
Query: 167 EQYE------ESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEF 220
E + SL+ S L ++S + + P+ELA QLTI+E + P E
Sbjct: 1042 EPEQINSGTSGSLLS-PPASLLPRVSGRALRLTDIAPLELARQLTILEFTLYQRIKPTEC 1100
Query: 221 VQT-FAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKY 279
+Q +A Q + + L T N+ A W +A IL+ +K
Sbjct: 1101 LQKIYADEVQGQLLAPNVRKVIL-------TANI--LAGW-------IALVILQHKDAKL 1144
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSA 327
RA+V + W+ T EC NL NF+S+ AII+ LN SPV RL++T SA
Sbjct: 1145 RAQVYKHWLQTAVECRNLNNFSSVAAIIAGLNSSPVSRLRRTRELLSA 1192
>UniRef50_Q552M5 Cluster: RasGEF domain-containing protein; n=2;
Dictyostelium discoideum|Rep: RasGEF domain-containing
protein - Dictyostelium discoideum AX4
Length = 1492
Score = 66.9 bits (156), Expect = 1e-09
Identities = 67/251 (26%), Positives = 111/251 (44%), Gaps = 30/251 (11%)
Query: 107 IALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKL--- 163
+ ++ +++ W YDF +R AL+ +I ++ ++S + K++D+
Sbjct: 1163 LGVLSIIKCWVDRHHYDF--ERNKALLSAIVAFLEGPVIDDGMEKVSNIILKIIDRKANE 1220
Query: 164 -------TALEQYEESLVDITQVSSLDQLSQGD-ILTL-GLTPVELANQLTIVELHRLSF 214
TAL + + S LS+ D I TL +E+A QLT++E S
Sbjct: 1221 AEARRTGTALVMHTSTSHCKFPPSIPPSLSKPDQIPTLQNFDDLEIARQLTLIEHEAYSM 1280
Query: 215 VGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKG 274
V P E + + S I +I R+ N L VAT+I++
Sbjct: 1281 VKPNECINL--------AFSKSDKEIRAPNIINIIKRS--------NLLPLWVATEIVQE 1324
Query: 275 VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLR 334
+ RA +I++++ +C NL NFN++M I+S LN++PV RLKKTW R
Sbjct: 1325 ERLTKRANIIKKFISIADQCKNLNNFNAVMEILSGLNLTPVFRLKKTWETLPRKYLATFR 1384
Query: 335 QLELCVEPTGN 345
L + P N
Sbjct: 1385 HLNSLMAPKFN 1395
>UniRef50_Q9Y4G8 Cluster: Rap guanine nucleotide exchange factor 2;
n=29; Euteleostomi|Rep: Rap guanine nucleotide exchange
factor 2 - Homo sapiens (Human)
Length = 1499
Score = 66.9 bits (156), Expect = 1e-09
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 22/198 (11%)
Query: 156 LEKLLDKLTALEQY--EESLVDITQVSSLDQ---LSQGDILTLGLTPVELANQLTIVELH 210
L KL D++ +Y + ++ T S D L + I L L+ VE+A QL++
Sbjct: 672 LSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFE 731
Query: 211 RLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATD 270
+ P E++ + +S ++C NL+ + + N+ ++ VA++
Sbjct: 732 LFRNIEPTEYIDDLFKL---RSKTSCA--------------NLKRFEEVINQETFWVASE 774
Query: 271 ILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCG 330
IL+ R ++I+ ++ C NFNS+ AIIS LN++PV RL+ TW +
Sbjct: 775 ILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYE 834
Query: 331 QQLRQLELCVEPTGNHAR 348
+ + L+ +P+ N A+
Sbjct: 835 KLFQDLQDLFDPSRNMAK 852
>UniRef50_O15059 Cluster: Ral GEF with PH domain and SH3-binding
motif 1; n=80; Euteleostomi|Rep: Ral GEF with PH domain
and SH3-binding motif 1 - Homo sapiens (Human)
Length = 590
Score = 66.1 bits (154), Expect = 2e-09
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 80 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 123
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 124 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 183
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 184 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 219
>UniRef50_A2QFY6 Cluster: Contig An03c0040, complete genome; n=2;
Aspergillus|Rep: Contig An03c0040, complete genome -
Aspergillus niger
Length = 587
Score = 66.1 bits (154), Expect = 2e-09
Identities = 59/244 (24%), Positives = 105/244 (43%), Gaps = 7/244 (2%)
Query: 100 EKELNDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKL 159
+K+ ++ +L+ W + + + M +R I + ++ T +E
Sbjct: 190 QKQKTVRFRVINILKTWLERYWMEPPTESTMDFLRHIHAQIQPLTNVPTCSQLLTIIEHR 249
Query: 160 LDKLTALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEE 219
L L++Y + T L + + L L P+ELA QLTI+E + + P E
Sbjct: 250 LKGQDILKRYMTP-PNSTVPKPLTPRNMKKLKFLDLDPMELARQLTIIESRLFARIKPTE 308
Query: 220 FV----QTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWF--NRLSYLVATDILK 273
+ Q PP ++ +TS S + R A N+L+ V IL
Sbjct: 309 CLNKSWQKKDTDRPPSVPASRRTSTSTTSSTSSIERTTGVNATILHSNQLANWVGEMILA 368
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQL 333
+ K R +I+Q V C +L NF ++M++IS L SP+ RL +TW++ + + L
Sbjct: 369 QDEMKKRVSLIKQIVNIADNCRSLSNFATMMSLISGLATSPIYRLHRTWTQVNPKTRKLL 428
Query: 334 RQLE 337
++
Sbjct: 429 EDMQ 432
>UniRef50_Q16MY3 Cluster: Ral guanine nucleotide exchange factor
with ph domain and sh3 binding motif, ralgps; n=1; Aedes
aegypti|Rep: Ral guanine nucleotide exchange factor with
ph domain and sh3 binding motif, ralgps - Aedes aegypti
(Yellowfever mosquito)
Length = 543
Score = 65.7 bits (153), Expect = 2e-09
Identities = 49/179 (27%), Positives = 80/179 (44%), Gaps = 19/179 (10%)
Query: 171 ESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPP 230
+SL ++++D + I L ++P ELANQ+T+++ FA I P
Sbjct: 6 QSLPPNASIANIDSII---ISCLRVSPEELANQITLLDF------------PVFAAIQPD 50
Query: 231 QSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMT 290
+ S + + + N+ A+ FN + ++L G+ +K RA +I ++
Sbjct: 51 ELASCAWNKKN----KAELSPNVVAFTKRFNHTIFWTVQEVLNGISAKERAEIISHFIKV 106
Query: 291 GRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
R L N +SL AI SAL + V RL+K+W S QQ +L N A L
Sbjct: 107 ARHLHELNNLHSLFAITSALKSASVYRLEKSWVHVSKKDKQQFERLAEIFHDDNNWATL 165
>UniRef50_Q875L6 Cluster: Guanyl nucleotide exchange factor Sql2; n=2;
Ustilago maydis|Rep: Guanyl nucleotide exchange factor
Sql2 - Ustilago maydis (Smut fungus)
Length = 1441
Score = 65.7 bits (153), Expect = 2e-09
Identities = 52/176 (29%), Positives = 83/176 (47%), Gaps = 13/176 (7%)
Query: 172 SLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQ 231
S+V T +S+L + I L P+ELA QLTI++ + PEE + + +
Sbjct: 1114 SVVSKTLLSNLRNGNVDKIHLLDFDPLELARQLTILDSKLYCAIQPEELLGS-------K 1166
Query: 232 STSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTG 291
T K S + K ++ R++ ++ IL ++ R ++++ ++ G
Sbjct: 1167 FTKETKASGVTEDVHVKSMSSMST------RITGWISECILGESDARKRTQLLKFFIKLG 1220
Query: 292 RECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
C L NF++LMAI ALN S + RLKKTW S + Q VE T N+A
Sbjct: 1221 DRCEQLNNFHTLMAIQCALNSSTIARLKKTWDGLSTKYRGMMDQQRSAVEHTRNYA 1276
>UniRef50_Q95WR8 Cluster: PXF isoform C; n=4; Caenorhabditis|Rep:
PXF isoform C - Caenorhabditis elegans
Length = 1347
Score = 65.3 bits (152), Expect = 3e-09
Identities = 36/109 (33%), Positives = 63/109 (57%), Gaps = 1/109 (0%)
Query: 241 SLHHIDTKC-TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGN 299
+L +D+K + LE + FNR + VAT+I + RA++I++++ R C +L N
Sbjct: 798 NLFKLDSKYGSPKLEEFEQLFNREMWWVATEICTERHVQKRAKLIKKFIKVARYCRDLRN 857
Query: 300 FNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
FNS+ AI+S L+ V RL +W R S+ + L ++ V+P+ N ++
Sbjct: 858 FNSMFAIMSGLDKPAVRRLHSSWERVSSKYIRMLDEIHQLVDPSRNMSK 906
>UniRef50_Q7Q955 Cluster: ENSANGP00000013079; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000013079 - Anopheles gambiae
str. PEST
Length = 564
Score = 65.3 bits (152), Expect = 3e-09
Identities = 45/155 (29%), Positives = 76/155 (49%), Gaps = 16/155 (10%)
Query: 195 LTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLE 254
++P ELA Q+T+++ + + PEE TS T + H + N+
Sbjct: 24 VSPAELAAQITLLDFPIFNAIQPEEL------------TSCGWTKKNKHTL----APNVV 67
Query: 255 AYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSP 314
A+ FN ++ +IL GV K RA +I ++ ++ ++ N +SL A+ISAL +
Sbjct: 68 AFTKRFNHTTFWTVQEILNGVSPKDRAEIISHFIKVAKKLHDINNLHSLFAVISALKSAS 127
Query: 315 VMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
V RLK++W S QQL +L + + N + L
Sbjct: 128 VHRLKESWLLVSRKDQQQLDRLSHLFDESDNWSSL 162
>UniRef50_Q7S0V9 Cluster: Putative uncharacterized protein NCU09758.1;
n=1; Neurospora crassa|Rep: Putative uncharacterized
protein NCU09758.1 - Neurospora crassa
Length = 1191
Score = 64.5 bits (150), Expect = 5e-09
Identities = 35/98 (35%), Positives = 54/98 (55%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N++A + + LS LV IL+ + K RA +I+ W+ G + L N++ LMA+ ALN
Sbjct: 951 NVKAMSTFTTGLSNLVVDTILQFDEIKKRAAIIKHWIKIGSQFLALNNYDGLMAVTCALN 1010
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
S + RL+ TW S+ + L+ L+ VE NH L
Sbjct: 1011 DSSIKRLRMTWDTISSRRKETLKSLQAIVEIGQNHKAL 1048
>UniRef50_Q3MIN7 Cluster: Ral guanine nucleotide dissociation
stimulator-like 3; n=13; Theria|Rep: Ral guanine
nucleotide dissociation stimulator-like 3 - Homo sapiens
(Human)
Length = 710
Score = 64.5 bits (150), Expect = 5e-09
Identities = 79/292 (27%), Positives = 125/292 (42%), Gaps = 43/292 (14%)
Query: 89 QIGKAEVKDLVEKELNDMIALVRVLRQWTSMFPYDFRDDRV---MALVRSITQRCAAEHM 145
+I K V+DL + ++ A+V VL W P DFRD V + VR+ A
Sbjct: 126 EIKKTAVQDLSFNK--NLRAVVSVLGSWLQDHPQDFRDPPVHSDLGSVRTFLGWAAPGSA 183
Query: 146 ESVRVEMSTTLEKLLDKLTALEQYEESLV-----DITQVSSLDQ-----------LSQGD 189
E+ + E LE L++ ++ E V + Q S D + QG
Sbjct: 184 EAQKAEK--LLEDFLEEAEREQEEEPPQVWTGPPRVAQTSDPDSSEACAEEEEGLMPQGP 241
Query: 190 ILTLGLTPVELANQLTIVELHRLSFVGPEEFV-QTFAPIHPPQSTSACKTSISLHHIDTK 248
L L + E+A QLT+++L S V E + ++ P + A T
Sbjct: 242 QL-LDFSVDEVAEQLTLIDLELFSKVRLYECLGSVWSQRDRPGAAGASPT---------- 290
Query: 249 CTRNLEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAI 306
+ A FN ++ V +L G+ + RA+ +E+W+ + C L NF+SL AI
Sbjct: 291 ----VRATVAQFNTVTGCVLGSVLGAPGLAAPQRAQRLEKWIRIAQRCRELRNFSSLRAI 346
Query: 307 ISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEK 358
+SAL +P+ RLK++W S R+L NH LS + F++
Sbjct: 347 LSALQSNPIYRLKRSWGAVSREPLSTFRKLSQIFSDENNH--LSSREILFQE 396
>UniRef50_UPI000069F86C Cluster: Ral guanine nucleotide dissociation
stimulator (RalGEF) (RalGDS).; n=1; Xenopus
tropicalis|Rep: Ral guanine nucleotide dissociation
stimulator (RalGEF) (RalGDS). - Xenopus tropicalis
Length = 640
Score = 64.1 bits (149), Expect = 7e-09
Identities = 35/97 (36%), Positives = 52/97 (53%), Gaps = 2/97 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V + L + +K + RA+VIE+W+ REC L NF+SL AI+SAL
Sbjct: 194 IRATVSQFNSVTNCVISTCLCDRSLKPQQRAKVIERWIEVARECRILKNFSSLRAILSAL 253
Query: 311 NMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
+ + RLKKTW S + +L NH+
Sbjct: 254 QCNAIHRLKKTWDEVSRESYRIFMELSEIFSDENNHS 290
>UniRef50_Q6CRG2 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome D of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome D of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 1537
Score = 64.1 bits (149), Expect = 7e-09
Identities = 33/97 (34%), Positives = 54/97 (55%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ + N L+ V+ I+K K RA++++ ++ +C+NL NF+S+ AI+SAL
Sbjct: 1308 NISNFITSSNHLTDFVSYTIVKETDLKKRAQILQFFIQVSEQCYNLKNFSSMTAIVSALY 1367
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
SP+ RLKKT+ R L +L ++ T N R
Sbjct: 1368 SSPIFRLKKTFDRLPKHILNSLDKLNTLMDSTRNFFR 1404
>UniRef50_Q9NZL6 Cluster: Ral guanine nucleotide dissociation
stimulator-like 1; n=23; Theria|Rep: Ral guanine
nucleotide dissociation stimulator-like 1 - Homo sapiens
(Human)
Length = 768
Score = 64.1 bits (149), Expect = 7e-09
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 276 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 335
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 336 QSNSIYRLKKTWA 348
>UniRef50_P28818 Cluster: Guanine nucleotide-releasing protein; n=24;
Euteleostomi|Rep: Guanine nucleotide-releasing protein -
Rattus norvegicus (Rat)
Length = 1244
Score = 64.1 bits (149), Expect = 7e-09
Identities = 32/90 (35%), Positives = 49/90 (54%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S L+A++IL+ + RA IE+WV C L N+N+++ I S++N S + RLK
Sbjct: 1057 FNHISNLIASEILRNEEVSARASTIEKWVAVADICRCLHNYNAVLEITSSINRSAIFRLK 1116
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW + S +L+ V G L
Sbjct: 1117 KTWLKVSKQTKSLFDKLQKLVSSDGRFKNL 1146
>UniRef50_Q54RZ8 Cluster: RasGEF; n=2; Dictyostelium discoideum|Rep:
RasGEF - Dictyostelium discoideum AX4
Length = 1457
Score = 63.7 bits (148), Expect = 9e-09
Identities = 33/98 (33%), Positives = 49/98 (50%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N++ D FNR S +V T+ILK SK R+ + ++ CF L N + +II LN
Sbjct: 1268 NIQISTDHFNRTSQVVVTEILKSKNSKQRSATLGYFISVAYCCFELNNLSGTASIIYGLN 1327
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+ + RLKK+WS+ L+ V P N+ L
Sbjct: 1328 SASIQRLKKSWSKLPKESMIAFEYLDKIVTPMKNYISL 1365
>UniRef50_O14827 Cluster: Ras protein-specific guanine
nucleotide-releasing factor 2; n=28; cellular
organisms|Rep: Ras protein-specific guanine
nucleotide-releasing factor 2 - Homo sapiens (Human)
Length = 1237
Score = 63.3 bits (147), Expect = 1e-08
Identities = 34/90 (37%), Positives = 47/90 (52%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S LVA+ I+ RA IE+WV C L N+N ++ I SALN S + RLK
Sbjct: 1050 FNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLK 1109
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW++ S + +L+ V G L
Sbjct: 1110 KTWAKVSKQTKALMDKLQKTVSSEGRFKNL 1139
>UniRef50_UPI00015616A3 Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator; n=3; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator - Equus caballus
Length = 556
Score = 62.9 bits (146), Expect = 2e-08
Identities = 32/79 (40%), Positives = 48/79 (60%), Gaps = 2/79 (2%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNR+ V T L V ++ RA+V+E+W+ REC L N +SL A++SAL P+ R
Sbjct: 349 FNRVVKCVMTSCLGDPNVTARGRAKVLERWIEVARECRALRNISSLHAVLSALQSVPIHR 408
Query: 318 LKKTWSRTSAVCGQQLRQL 336
LKKTW + S ++ ++L
Sbjct: 409 LKKTWGKVSRKSYRKFKKL 427
>UniRef50_Q9DE48 Cluster: Ras-associated protein; n=11;
Clupeocephala|Rep: Ras-associated protein - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 359
Score = 62.9 bits (146), Expect = 2e-08
Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRL+ V L +KS+ RAR++E+W+ C NF+SL AI+SAL +P+ R
Sbjct: 252 FNRLANAVTASCLWMTTLKSQQRARLLEKWISVAEACRTRKNFSSLYAILSALQSNPIHR 311
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
L+KTW T ++ +L N+++
Sbjct: 312 LRKTWQETDREAVKRYEELSDIFSEKDNYSQ 342
>UniRef50_Q54H95 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1371
Score = 62.9 bits (146), Expect = 2e-08
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 14/164 (8%)
Query: 182 LDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSIS 241
L L D L ++ +E+A Q+ +++ LS + E + + S C
Sbjct: 775 LKTLDGSDFSLLDISSIEVARQMALIDQTLLSKISSTELLS--------KKWSKCTDETQ 826
Query: 242 LHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFN 301
K N+ FN+ S V+++I+ SK R + ++ ++ + C+++ NFN
Sbjct: 827 ------KICPNILTMIGVFNQCSKWVSSEIVGEKSSKLRIKKLKYFIKIAQHCYDMQNFN 880
Query: 302 SLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
LM IIS L+ S V RL+ TW S+ + QLE V GN
Sbjct: 881 GLMLIISGLSCSSVTRLRGTWGSLSSRHRDRFDQLERFVNMEGN 924
>UniRef50_UPI00015616DC Cluster: PREDICTED: hypothetical protein,
partial; n=1; Equus caballus|Rep: PREDICTED:
hypothetical protein, partial - Equus caballus
Length = 420
Score = 62.1 bits (144), Expect = 3e-08
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNR+ V T L V ++ RA+V+E+W+ REC L N +SL A++SAL P+ R
Sbjct: 352 FNRVVKCVMTSCLGDPNVTARGRAKVLERWIEVARECRALRNISSLHAVLSALQSVPIHR 411
Query: 318 LKKTWSRTS 326
LKKTW + S
Sbjct: 412 LKKTWGKVS 420
>UniRef50_UPI00004D6636 Cluster: ral guanine nucleotide dissociation
stimulator-like 3; n=3; Xenopus tropicalis|Rep: ral
guanine nucleotide dissociation stimulator-like 3 -
Xenopus tropicalis
Length = 794
Score = 62.1 bits (144), Expect = 3e-08
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 11/123 (8%)
Query: 215 VGPEEFVQTFAPIHPPQST----SACKTSISL-HHIDTKCTRNL----EAYADWFNRLSY 265
V E F F P PPQ +C S+ D K RN+ A FN ++
Sbjct: 300 VSIEMFNLLFCPPLPPQDLFQKLQSCHCLGSIWSQRDKKENRNVAPSVRATVAQFNAVTA 359
Query: 266 LVATDILKGV--KSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
V +L V K + RA+V+E+W+ + C L NF+SL AI+SAL +P+ RLK+TW+
Sbjct: 360 CVIASVLSDVQLKPQQRAKVLEKWICIAQHCRFLRNFSSLRAILSALQSNPLYRLKRTWA 419
Query: 324 RTS 326
S
Sbjct: 420 AVS 422
>UniRef50_Q4RPN7 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12
SCAF15007, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 933
Score = 62.1 bits (144), Expect = 3e-08
Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 2/90 (2%)
Query: 260 FNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FN ++ V T L +K RAR++E+W+ REC L NF+SL AI+SAL + + R
Sbjct: 394 FNSVTNCVITTCLSNPALKPNQRARLLERWIDVARECRILKNFSSLRAILSALQCNAIHR 453
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
LK+TW S + R+L N++
Sbjct: 454 LKRTWEEVSRESFRTFRELSEIFSDDNNYS 483
>UniRef50_Q12967 Cluster: Ral guanine nucleotide dissociation
stimulator; n=29; Eutheria|Rep: Ral guanine nucleotide
dissociation stimulator - Homo sapiens (Human)
Length = 914
Score = 62.1 bits (144), Expect = 3e-08
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 430 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 489
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 490 QSNSIHRLKKTWEDVS 505
>UniRef50_Q8TEU7 Cluster: Rap guanine nucleotide exchange factor 6;
n=104; Deuterostomia|Rep: Rap guanine nucleotide
exchange factor 6 - Homo sapiens (Human)
Length = 1601
Score = 61.7 bits (143), Expect = 4e-08
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 899 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 958
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 959 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 995
>UniRef50_Q0E949 Cluster: CG5522-PA, isoform A; n=5;
Endopterygota|Rep: CG5522-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 702
Score = 61.3 bits (142), Expect = 5e-08
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 16/144 (11%)
Query: 180 SSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTS 239
+S+ QL + L + LANQ+T+++ FA I P + S+C +
Sbjct: 150 ASIKQLDAVILSALRVPADVLANQITLLDF------------PVFAQIQPDE-LSSCAWT 196
Query: 240 ISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGN 299
H++T N+ A+ FN S+ +IL + K RA +I ++ ++ L N
Sbjct: 197 KKDKHVNTP---NIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNN 253
Query: 300 FNSLMAIISALNMSPVMRLKKTWS 323
+SL AIISA+ + + RL KTW+
Sbjct: 254 LHSLFAIISAMQSASIYRLTKTWA 277
>UniRef50_Q54H67 Cluster: Ras guanine nucleotide exchange factor; n=2;
Dictyostelium discoideum|Rep: Ras guanine nucleotide
exchange factor - Dictyostelium discoideum AX4
Length = 1298
Score = 60.9 bits (141), Expect = 6e-08
Identities = 51/185 (27%), Positives = 82/185 (44%), Gaps = 21/185 (11%)
Query: 169 YEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIH 228
+ E +V T SS + S I L + PVE+A QLT+++ + P +F H
Sbjct: 939 FPEPIVPKTFFSSPN--STFSITFLDIHPVEIARQLTLIDYELFKKLSPTDFY------H 990
Query: 229 PPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S K + NL + + N +SY VAT+IL K+R V+++++
Sbjct: 991 TAWSKPDAKEKVP----------NLINFINRSNTVSYWVATEILSSSNIKHRVSVLKRFI 1040
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
N+N+L I+ LN+ + RLKKTW ++ +QL L+ + T
Sbjct: 1041 TIAEILRKFHNWNTLTGILMGLNLGSIQRLKKTW---ESIDKKQLDSLQNLINLTSERLN 1097
Query: 349 LSGNR 353
S R
Sbjct: 1098 YSNYR 1102
>UniRef50_UPI00015A741B Cluster: Hypothetical protein; n=3; Danio
rerio|Rep: Hypothetical protein - Danio rerio
Length = 723
Score = 60.5 bits (140), Expect = 8e-08
Identities = 25/45 (55%), Positives = 34/45 (75%)
Query: 279 YRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
YRA++IE+W+ +EC L NF+SL AI+SAL + V RLKKTW+
Sbjct: 308 YRAKIIEKWISVAQECHQLRNFSSLRAILSALQSNAVYRLKKTWA 352
>UniRef50_A4QP96 Cluster: Putative uncharacterized protein; n=4;
Danio rerio|Rep: Putative uncharacterized protein -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 472
Score = 60.5 bits (140), Expect = 8e-08
Identities = 25/45 (55%), Positives = 34/45 (75%)
Query: 279 YRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
YRA++IE+W+ +EC L NF+SL AI+SAL + V RLKKTW+
Sbjct: 36 YRAKIIEKWISVAQECHQLRNFSSLRAILSALQSNAVYRLKKTWA 80
>UniRef50_Q0ULM6 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1032
Score = 60.5 bits (140), Expect = 8e-08
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 5/131 (3%)
Query: 240 ISLHHIDTKCTRNLE---AYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFN 296
+SL+ + K RNLE + FN + YLV IL K K+RA ++E+W+ R+
Sbjct: 693 VSLNAEERKRCRNLENVTRMTEHFNHVFYLVQNYILLRDKPKHRALMLEKWMKIARQLRK 752
Query: 297 LGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH--ARLSGNRV 354
L N+NSL AIIS + +PV RL T +L++ + +H RL+ +
Sbjct: 753 LNNYNSLTAIISGIKSAPVHRLLATRDLVPQATTHDFLKLDILMGSQKSHFAYRLAWDNS 812
Query: 355 NFEKCALLSKH 365
+ E+ + H
Sbjct: 813 SGERIPYIPLH 823
>UniRef50_Q13972 Cluster: Guanine nucleotide-releasing protein; n=24;
Euteleostomi|Rep: Guanine nucleotide-releasing protein -
Homo sapiens (Human)
Length = 1275
Score = 60.5 bits (140), Expect = 8e-08
Identities = 30/90 (33%), Positives = 48/90 (53%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S L+A++I++ R IE+WV C L N+N+++ I S++N S + RLK
Sbjct: 1088 FNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLK 1147
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW + S + +L+ V G L
Sbjct: 1148 KTWLKVSKQTKALIDKLQKLVSSEGRFKNL 1177
>UniRef50_Q19852 Cluster: Putative uncharacterized protein F28B4.2;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein F28B4.2 - Caenorhabditis elegans
Length = 860
Score = 60.1 bits (139), Expect = 1e-07
Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 253 LEAYADWFNRLSYLVATDI-LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
++A + FN +S V T I L + +YRA++I +W+ RE L NF+SL A++S+L
Sbjct: 276 VKATIEQFNSVSQRVMTSIVLPDCRPEYRAKIISKWIDIARELRALKNFSSLKAVLSSLQ 335
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVE 341
PV RLK W+ Q R+L E
Sbjct: 336 SEPVHRLKSAWNSVPNRSISQFRELSSIYE 365
>UniRef50_A4QNU6 Cluster: Zgc:162151 protein; n=6; Euteleostomi|Rep:
Zgc:162151 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 708
Score = 59.7 bits (138), Expect = 1e-07
Identities = 69/267 (25%), Positives = 117/267 (43%), Gaps = 39/267 (14%)
Query: 112 VLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLE-KLLDKLTALEQYE 170
++R W + FP +F D + L+R E E+ KLLD ++ + Y+
Sbjct: 77 LMRYWIAEFPAEF--DLDLGLIR------LTEEFRDAAAELGGDKHIKLLD-ISTIPSYD 127
Query: 171 ESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVE---LHRLSFVGPEEFVQTFAPI 227
+ +TQ + + +L L P+ELA LT +E + R+SF + +V I
Sbjct: 128 W-MRKLTQRKKQVKKGKASLLFDHLEPIELAEHLTFLEYKSIRRISFTDYQSYV-----I 181
Query: 228 HPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
H C +D LE FN +S V +L + ++RA VI ++
Sbjct: 182 H------GCL-------VDNP---TLERSIALFNGISQWVQLMVLSKLTPQHRAEVITKY 225
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
+ ++ +L NFN+LMA++ L+ S + RLK+T S S + ++ V GN+
Sbjct: 226 IHVAQKLLHLQNFNTLMAVVGGLSHSSISRLKETHSHLSPEVTKIWNEMTELVSSNGNYC 285
Query: 348 ---RLSGNRVNFEKCALLSKHVSTQLA 371
+ G F K +L H+ +A
Sbjct: 286 AYRKAFGESKGF-KIPILGVHLKDLIA 311
>UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 968
Score = 59.7 bits (138), Expect = 1e-07
Identities = 29/95 (30%), Positives = 50/95 (52%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL+ FN + Y V T+I + R ++++++ C + N NS AII ALN
Sbjct: 768 NLDICLSRFNEVHYWVITEICLATQLSKRVFLLKKFIKIASYCKDYKNLNSAFAIIMALN 827
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ + RL +TW + + R+L+ ++P+GNH
Sbjct: 828 CAAISRLTQTWEKIPNKYKKLYRELDAILDPSGNH 862
>UniRef50_A7SDN8 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 133
Score = 59.7 bits (138), Expect = 1e-07
Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSK---YRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
++A D FN +S V + IL+ ++K R R I QW+ + C NL NF+SL AIISA
Sbjct: 48 VQATVDQFNAVSLKVLSSILRTPENKSPAQRGRYINQWINIAQCCRNLKNFSSLKAIISA 107
Query: 310 LNMSPVMRLKKTW 322
L + + RLKK+W
Sbjct: 108 LQSASIHRLKKSW 120
>UniRef50_A3LZZ6 Cluster: Predicted protein; n=2; Pichia|Rep:
Predicted protein - Pichia stipitis (Yeast)
Length = 1325
Score = 59.7 bits (138), Expect = 1e-07
Identities = 34/94 (36%), Positives = 50/94 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ A+ N+L+ VA IL+ +K R +VI +V +C NF+S+ AIISAL
Sbjct: 1091 NITAFIKASNQLTNYVAYMILRKTDAKKRIQVIRYFVQVAEKCRQYNNFSSMTAIISALY 1150
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
S + RLKKTW SA L+ + + + N
Sbjct: 1151 SSSIHRLKKTWKYVSADTLSHLQSMNKLMNSSRN 1184
>UniRef50_Q555R4 Cluster: Ras guanine nucleotide exchange factor; n=3;
Eukaryota|Rep: Ras guanine nucleotide exchange factor -
Dictyostelium discoideum AX4
Length = 1721
Score = 59.3 bits (137), Expect = 2e-07
Identities = 52/240 (21%), Positives = 111/240 (46%), Gaps = 17/240 (7%)
Query: 107 IALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTAL 166
+ +V ++ W DF DD+++ ++ R ++ + V + ++K + +
Sbjct: 1359 LRVVSFMQTWIERNFNDF-DDQLIGQLKEFRTRLLMDNNNDLAVILGGLIKKKEAERSLS 1417
Query: 167 EQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAP 226
++ + + ++ D L L L E+A QLT+++ + S + P E +
Sbjct: 1418 KERSTNHLTFPELMIPDGQKSPTALFLLLNESEIARQLTLIDFNIFSKIQPTELLD---- 1473
Query: 227 IHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQ 286
QS + K S+ + N+ + N+ S+ V++ IL + R +V E+
Sbjct: 1474 ----QSWN--KDSLKFK------SPNVIEMINRANKFSFWVSSQILWQEDIEERVKVFEK 1521
Query: 287 WVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+++ + + NFN+L+AI + LN +P++RLKKT++ S LE + +G++
Sbjct: 1522 FILISKYLREMNNFNTLLAIFTGLNTAPILRLKKTFALLSPNSLSIYNSLEKLMNSSGSY 1581
>UniRef50_Q02342 Cluster: Cell division control protein 25; n=1;
Lachancea kluyveri|Rep: Cell division control protein 25
- Saccharomyces kluyveri (Yeast) (Saccharomyces
silvestris)
Length = 1095
Score = 59.3 bits (137), Expect = 2e-07
Identities = 32/99 (32%), Positives = 52/99 (52%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
++N+ + N L+ V+ I+K K R ++I+ ++ C L NF+SL AIISA
Sbjct: 851 SKNITEFISNSNHLTNYVSFMIVKQTDIKKRIQLIQFFINVAAHCHELNNFSSLTAIISA 910
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
L SP+ RLK+TW+ + L +L ++ N R
Sbjct: 911 LYSSPIYRLKRTWAAVPEEYKKLLEELNTLMDSAKNFIR 949
>UniRef50_UPI00015616C2 Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator; n=3; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator - Equus caballus
Length = 809
Score = 58.8 bits (136), Expect = 3e-07
Identities = 25/56 (44%), Positives = 37/56 (66%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQ 335
RARV+E W+ +EC LGN+ SL AI+SAL + RL+KTW R + ++L++
Sbjct: 559 RARVVELWIQVAKECRVLGNYASLRAIVSALQSPSISRLQKTWGRVARKSSRKLKR 614
>UniRef50_UPI0000E47C73 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to conserved
hypothetical protein - Strongylocentrotus purpuratus
Length = 1211
Score = 58.8 bits (136), Expect = 3e-07
Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 248 KCTR--NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMA 305
K TR N+ A FN +S LV+++IL+ RA IE+W C + NFNS++
Sbjct: 1027 KATRAPNILAVTRRFNEVSKLVSSEILRQKSVAARALAIERWAGVADICRCMHNFNSVLE 1086
Query: 306 IISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTG 344
I SAL S V RLKK W + L +L++ V G
Sbjct: 1087 ITSALMNSSVYRLKKVWEKVPKQTKTLLDKLQVLVSSDG 1125
>UniRef50_Q179F5 Cluster: Guanine nucleotide exchange factor; n=2;
Aedes aegypti|Rep: Guanine nucleotide exchange factor -
Aedes aegypti (Yellowfever mosquito)
Length = 1450
Score = 58.8 bits (136), Expect = 3e-07
Identities = 29/96 (30%), Positives = 51/96 (53%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
L +A+ NR + V T++ R ++I+Q++ R C NFNSL AIIS L
Sbjct: 809 LVKFAELVNREMFWVVTEVCSEHNMMRRCKIIKQFIKIARHCKECKNFNSLFAIISGLGH 868
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+ V RL++TW + + + L+ ++P+ N ++
Sbjct: 869 AAVSRLRQTWEKLPSKYQKLFNDLQELMDPSRNMSK 904
>UniRef50_A7SU64 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 603
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/155 (27%), Positives = 69/155 (44%), Gaps = 16/155 (10%)
Query: 195 LTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLE 254
+TP A QLT ++L + PEEF S+C + + + N+
Sbjct: 63 VTPDNFARQLTYMDLAVFKSIQPEEF-------------SSCGWTKKNKSVQSP---NVV 106
Query: 255 AYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSP 314
A FN +S+ V +IL K K R V+ ++ + + + N +SL A+I+ L +P
Sbjct: 107 ALTKRFNHVSFWVVREILNAKKLKTRVAVMSHFIRIAKRLYEMNNLHSLKAVIAGLQSAP 166
Query: 315 VMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
V RL +TW + S +LE + N RL
Sbjct: 167 VYRLNQTWEQLSRRDHTIFEKLEDLLSEDQNRKRL 201
>UniRef50_UPI0000E478B1 Cluster: PREDICTED: similar to RALGPS1
protein, partial; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to RALGPS1 protein,
partial - Strongylocentrotus purpuratus
Length = 277
Score = 58.4 bits (135), Expect = 3e-07
Identities = 28/78 (35%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Query: 246 DTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMA 305
+T C N+ A++ FN++S+ V ++L +K RA VI ++ ++ F++ N ++ MA
Sbjct: 132 NTLCP-NIVAFSKRFNQVSFWVVHEVLITQMTKARAEVIGHFIKVAKKLFDINNLHATMA 190
Query: 306 IISALNMSPVMRLKKTWS 323
IISAL+ + + RL KTW+
Sbjct: 191 IISALHSASIFRLTKTWN 208
>UniRef50_A6R1V9 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 930
Score = 58.4 bits (135), Expect = 3e-07
Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ D FN L+ VA+ +L K K+RA +E+++ + L N+NSL A+I+ LN
Sbjct: 720 NVNRMIDQFNHLALFVASMVLLRDKPKHRAEALEKFMNIAMKLRQLNNYNSLGAVIAGLN 779
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH--ARLSGNRVNFEKCALLSKH 365
+PV RL +T S + +Q L + + +H RL+ + EK L H
Sbjct: 780 GTPVFRLSQTRELVSPMVQKQFMSLVILMGTQKSHFAYRLAWDNSFAEKIPFLPLH 835
>UniRef50_P04821 Cluster: Cell division control protein 25; n=2;
Saccharomyces cerevisiae|Rep: Cell division control
protein 25 - Saccharomyces cerevisiae (Baker's yeast)
Length = 1589
Score = 58.4 bits (135), Expect = 3e-07
Identities = 30/88 (34%), Positives = 47/88 (53%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N L+ V+ I+K K R+++ + +V + C L NF+S+ AI+SAL SP+ RLKK
Sbjct: 1355 NTLTNFVSHTIVKQADVKTRSKLTQYFVTVAQHCKELNNFSSMTAIVSALYSSPIYRLKK 1414
Query: 321 TWSRTSAVCGQQLRQLELCVEPTGNHAR 348
TW S L+ L ++ N +
Sbjct: 1415 TWDLVSTESKDLLKNLNNLMDSKRNFVK 1442
>UniRef50_Q5TND5 Cluster: ENSANGP00000025467; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000025467 - Anopheles gambiae
str. PEST
Length = 1021
Score = 58.0 bits (134), Expect = 4e-07
Identities = 28/96 (29%), Positives = 51/96 (53%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
L +A+ NR + V T++ R ++I+Q++ R C NFNSL AI+S L
Sbjct: 761 LVRFAELVNREMFWVVTEVCSEHNMMRRCKIIKQFIKIARHCKECKNFNSLFAIVSGLGH 820
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+ V RL++TW + + + L+ ++P+ N ++
Sbjct: 821 AAVSRLRQTWEKLPSKYQKLFNDLQDLMDPSRNMSK 856
>UniRef50_Q553C1 Cluster: Ras guanine nucleotide exchange factor; n=3;
Dictyostelium discoideum|Rep: Ras guanine nucleotide
exchange factor - Dictyostelium discoideum AX4
Length = 1138
Score = 58.0 bits (134), Expect = 4e-07
Identities = 62/246 (25%), Positives = 116/246 (47%), Gaps = 32/246 (13%)
Query: 114 RQWTSMFPYDFRDDRVMALVRSITQRCAA--EHMESVRVEMSTTLEKLLDKL------TA 165
++W + DF+++ + L++ + C+ E + + + T+L LL+ + T
Sbjct: 801 QKWVEVCWSDFKEEHIELLLKFLND-CSEQIEKLVTGSFALRTSLNLLLNIINMKRDGTY 859
Query: 166 LEQYEESLVDITQVSSLDQLSQG-DILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTF 224
+ + EE+ + QL DI + L P E+A QLTI++ L+ + ++ + +
Sbjct: 860 ITEEEETFEQPAPIPDFIQLPNCVDINLMDLRPHEIARQLTILDHELLTQITKQQMLD-Y 918
Query: 225 APIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVI 284
A +H S S K + D FN L V+T+I+ + + R I
Sbjct: 919 A-VHQTNSPSIVKVT------------------DRFNYLVLWVSTEIVLSLTIEKRIETI 959
Query: 285 EQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS-RTSAVCGQQLRQLELCVEPT 343
++V C+ L NFNS +AII+A++ + +LK+TW + +++L+ + PT
Sbjct: 960 FKFVNIALNCWYLKNFNSAIAIIAAMSKPSIEKLKQTWGFIRNTKANAPIQELKELILPT 1019
Query: 344 GNHARL 349
N ARL
Sbjct: 1020 -NVARL 1024
>UniRef50_A6R7Z9 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized
protein - Ajellomyces capsulatus NAm1
Length = 1201
Score = 58.0 bits (134), Expect = 4e-07
Identities = 56/233 (24%), Positives = 105/233 (45%), Gaps = 20/233 (8%)
Query: 100 EKELNDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKL 159
+K++ I +V +++ W + + DD M L++ + + + + S L L
Sbjct: 841 QKQIPIRIRVVNIMKNWFENYWMEPNDDANMRLLQRV-YAFVKDSIGKAKTPGSQQLLSL 899
Query: 160 LD-KLTALEQYEESLVDITQVSSLDQLSQGDILTL---GLTPVELANQLTIVELHRLSFV 215
+D ++ + + LV ++ + ++ L + P+E A QLTI+E + +
Sbjct: 900 IDQRMRGQDTSAKRLVPTISGNAPPPILPKNLKKLKFLDIDPMEFARQLTIIESRLYARI 959
Query: 216 GPEEFV-QTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKG 274
P E + +T+ P N++A N+L+ VA IL
Sbjct: 960 KPTECLNKTWQKKLVPDEPDPAA--------------NVKALILHSNQLTNWVAEMILHQ 1005
Query: 275 VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSA 327
K R VI+ +V+ C + N+++L +IISAL +PV RL +TW++ SA
Sbjct: 1006 QDVKRRVVVIKHFVLIAERCRAMNNYSTLTSIISALGTAPVHRLNRTWAQVSA 1058
>UniRef50_Q6C867 Cluster: Similarities with sp|P43069 Candida albicans
Cell division control protein 25; n=1; Yarrowia
lipolytica|Rep: Similarities with sp|P43069 Candida
albicans Cell division control protein 25 - Yarrowia
lipolytica (Candida lipolytica)
Length = 1189
Score = 57.6 bits (133), Expect = 6e-07
Identities = 34/94 (36%), Positives = 48/94 (51%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ + N L+ VA IL +K RA VI+ +V +C + NF+S+ AIISAL
Sbjct: 975 NIRKFIQNSNCLTNWVAACILAEKDTKKRASVIKYFVQVSEQCRQINNFSSMTAIISALY 1034
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
S + RLKK+W SA L + + T N
Sbjct: 1035 SSTIHRLKKSWELVSARTMASLENMNKLMNSTRN 1068
>UniRef50_Q5K7Q6 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1437
Score = 57.6 bits (133), Expect = 6e-07
Identities = 31/100 (31%), Positives = 53/100 (53%)
Query: 248 KCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAII 307
K L+A + N+++ VA IL +K RA +++ ++ +C + NF ++ A++
Sbjct: 1223 KTVPELKALSTHSNQVTGWVADSILNEGDAKRRAGLLKFFIKLADKCLLINNFFTMFAVL 1282
Query: 308 SALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
LN S ++RLKKTW S + +L +E T NHA
Sbjct: 1283 GGLNSSTILRLKKTWDALSVKYKILIERLRGIIEHTKNHA 1322
>UniRef50_P14771 Cluster: Guanine nucleotide exchange factor SDC25;
n=2; Saccharomyces cerevisiae|Rep: Guanine nucleotide
exchange factor SDC25 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 1252
Score = 57.6 bits (133), Expect = 6e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
L + + N+L+ ++ ++K RA+++ ++ C NF+S+ AIISAL
Sbjct: 995 LNEFISFANKLTNFISYSVVKEADKSKRAKLLSHFIFIAEYCRKFNNFSSMTAIISALYS 1054
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
SP+ RL+KTW L+ L ++P N
Sbjct: 1055 SPIYRLEKTWQAVIPQTRDLLQSLNKLMDPKKN 1087
>UniRef50_Q8IS10 Cluster: Nucleotide exchange factor RasGEF P; n=2;
Dictyostelium discoideum|Rep: Nucleotide exchange factor
RasGEF P - Dictyostelium discoideum (Slime mold)
Length = 1502
Score = 57.2 bits (132), Expect = 8e-07
Identities = 69/266 (25%), Positives = 109/266 (40%), Gaps = 32/266 (12%)
Query: 97 DLVEKELNDM-IALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTT 155
D K+ D + + L++W YDF D + I H + ++ T
Sbjct: 1174 DQFNKQRKDTHLKICNFLKRWVEKHFYDFDQDLLQEFNTFIANCRVINHQDFLQ----KT 1229
Query: 156 LEKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILTL-GLTPVELANQLTIVELHRLSF 214
L K KL L E LV T + L + I + P E+A QLT++E +
Sbjct: 1230 LNK---KLIPLSSSELKLVFSTPTPA-PILPKTPITCFEDMDPAEIARQLTLIEFNLFKN 1285
Query: 215 VGPEEFVQTFAPIHPPQSTSACKTSISLHHID-TKCTRNLEAYADWFNRLSYLVATDILK 273
+ +EF+ S+S D K + NL FN +S V + I+K
Sbjct: 1286 IANKEFL-----------------SLSWQKQDKEKRSPNLLKMIYRFNEVSNWVTSTIVK 1328
Query: 274 GVKS-KYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQ 332
+ K RA +++++ E L NFN + I+S L+ + V RLK TW+ S QQ
Sbjct: 1329 ETTNIKKRASYLKRFIKLAEELRKLNNFNGVFVIVSGLHSASVNRLKNTWAEISK---QQ 1385
Query: 333 LRQLELCVEPTGNHARLSGNRVNFEK 358
+Q E V T + + R+ +
Sbjct: 1386 QKQFEEFVALTSPQSSFASYRLELRQ 1411
>UniRef50_A7TNK1 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1302
Score = 57.2 bits (132), Expect = 8e-07
Identities = 31/101 (30%), Positives = 53/101 (52%)
Query: 245 IDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLM 304
I + ++++ + N+L+ V+ I+ + K RA++I+ W+ C + NF+S+
Sbjct: 1048 IGSSSSKSISHFISNANKLTNFVSYIIVTQPEVKKRAKLIQFWITVAIHCQAMNNFSSMT 1107
Query: 305 AIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
AIISAL SP+ RL KTW + L+ L + T N
Sbjct: 1108 AIISALYSSPIYRLTKTWKLIGVDHVENLKALNNLMNSTKN 1148
>UniRef50_Q8IV61 Cluster: RAS guanyl-releasing protein 3; n=79;
Euteleostomi|Rep: RAS guanyl-releasing protein 3 - Homo
sapiens (Human)
Length = 690
Score = 57.2 bits (132), Expect = 8e-07
Identities = 60/237 (25%), Positives = 103/237 (43%), Gaps = 33/237 (13%)
Query: 113 LRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEES 172
+R W FP +F D + L+R E V ++ L ++++ Y+
Sbjct: 78 MRYWILKFPAEFNLD--LGLIRM------TEEFREVASQLGYEKHVSLIDISSIPSYDW- 128
Query: 173 LVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVE---LHRLSFVGPEEFVQTFAPIHP 229
+ +TQ + + + +L L P+ELA LT +E R+SF + +V IH
Sbjct: 129 MRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV-----IH- 182
Query: 230 PQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVM 289
C ++ T LE FN +S V +L + RA VI +++
Sbjct: 183 -----GC--------LENNPT--LERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFIN 227
Query: 290 TGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
++ L NFN+LMA++ L+ S + RLK+T S S+ + ++ V GN+
Sbjct: 228 VAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNY 284
>UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p -
Drosophila melanogaster (Fruit fly)
Length = 861
Score = 56.8 bits (131), Expect = 1e-06
Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 243 HHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNS 302
HH K T NL+ + FN + Y + T+++ R ++ +++ C N N+
Sbjct: 654 HHFG-KITANLDVFLRRFNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNA 712
Query: 303 LMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A++ L+ V RL++TW + + + ++ E ++P+ NH
Sbjct: 713 FFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFEALIDPSRNH 756
>UniRef50_P26674 Cluster: Protein ste6; n=1; Schizosaccharomyces
pombe|Rep: Protein ste6 - Schizosaccharomyces pombe
(Fission yeast)
Length = 911
Score = 56.8 bits (131), Expect = 1e-06
Identities = 54/200 (27%), Positives = 85/200 (42%), Gaps = 20/200 (10%)
Query: 162 KLTALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFV 221
K+ ++ + L D++ +S D + D L L L P E+A QL I+E S + +F+
Sbjct: 629 KMLEGKELSQELEDLSLHNSPDPIIYKDELVLLLPPREIAKQLCILEFQSFSHISRIQFL 688
Query: 222 QTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRA 281
I + + K S ++ N L V I++ + + R
Sbjct: 689 ---TKIWDNLNRFSPKEKTSTFYLS--------------NHLVNFVTETIVQEEEPRRRT 731
Query: 282 RVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVE 341
V+ ++ L NF SL +IISALN SP+ RL+KTW+ ++ + L EL
Sbjct: 732 NVLAYFIQVCDYLRELNNFASLFSIISALNSSPIHRLRKTWANLNS---KTLASFELLNN 788
Query: 342 PTGNHARLSGNRVNFEKCAL 361
T S R E C L
Sbjct: 789 LTEARKNFSNYRDCLENCVL 808
>UniRef50_Q4SD50 Cluster: Chromosome 1 SCAF14643, whole genome
shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 1
SCAF14643, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 742
Score = 56.0 bits (129), Expect = 2e-06
Identities = 27/66 (40%), Positives = 43/66 (65%), Gaps = 2/66 (3%)
Query: 260 FNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FN ++ V + +LK ++ RARVI++W+ +EC NF+SL AI+SAL +P+ R
Sbjct: 259 FNAVTACVVSTVLKHRPLRPHVRARVIQRWIDIAQECRIRKNFSSLRAIVSALQSNPLYR 318
Query: 318 LKKTWS 323
LK+ W+
Sbjct: 319 LKRVWA 324
>UniRef50_A2R650 Cluster: Similarity: N-terminal half differs from all
homologs; n=14; Pezizomycotina|Rep: Similarity:
N-terminal half differs from all homologs - Aspergillus
niger
Length = 1362
Score = 56.0 bits (129), Expect = 2e-06
Identities = 63/273 (23%), Positives = 121/273 (44%), Gaps = 20/273 (7%)
Query: 78 TEKSDIEYRDGQIGKAEVKDLVEKELNDM-IALVRVLRQWTSMFPYDFRDDRVMALVRSI 136
TE+ +I+ G + E++ ++++ + +V +L+ W F + D+ MAL++ +
Sbjct: 845 TERFNIQPPPG-LNNDEMQMWIDRKQKPIRFRVVNILKSWFENFWMEPNDEPHMALLQHV 903
Query: 137 TQRCAAEHMESVRVEMSTTLEKLLD-KLTALEQYEESLVDITQVSSLDQL---SQGDILT 192
+ + + + S L +++ +L + + LV ++ + + +
Sbjct: 904 -HAFTKDSIATTKTPGSPQLLAVIEQRLRGQDNTVKRLVPTQATAAPTPIIPKNMKKLKF 962
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L + E A QLTI+E S + P E + T K + + N
Sbjct: 963 LDIDATEFARQLTIIESRLYSKIRPTECLN---------KTWQKKVGPD----EPEPASN 1009
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
++A N+L+ VA IL K R VI+ +V +C L N+++L +IISAL
Sbjct: 1010 VKALILHSNQLTNWVAEMILNQSDVKKRVVVIKHFVNVADKCRALNNYSTLTSIISALGT 1069
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
+P+ RL +TW++ S L Q+ + T N
Sbjct: 1070 APIHRLGRTWAQVSGRTSTVLEQMRRLMASTKN 1102
>UniRef50_P43069 Cluster: Cell division control protein 25; n=5;
Saccharomycetales|Rep: Cell division control protein 25 -
Candida albicans (Yeast)
Length = 1333
Score = 56.0 bits (129), Expect = 2e-06
Identities = 29/85 (34%), Positives = 45/85 (52%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N+L+ V IL+ K R ++I ++ +C NF+S+ AIISAL SP+ RLKK
Sbjct: 1118 NQLTNFVGYMILRKADPKKRVQIIRYFIQVADKCRQYNNFSSMTAIISALYSSPIHRLKK 1177
Query: 321 TWSRTSAVCGQQLRQLELCVEPTGN 345
TW +A L+ + + + N
Sbjct: 1178 TWEYMNADALSNLKNMNKLMNSSRN 1202
>UniRef50_UPI00015B5B5D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1557
Score = 55.6 bits (128), Expect = 2e-06
Identities = 55/231 (23%), Positives = 105/231 (45%), Gaps = 23/231 (9%)
Query: 109 LVRVLRQWTSMFPYDFR-DDRVMAL-VRSITQRCAAEHMESVRVEMSTTLEKLLDKLTAL 166
++ VLR W S DF D+++ L + + + ++ + ++ L +L+ K
Sbjct: 1217 VLNVLRHWVSKHAQDFELDNKLKNLTIEFLEDIIYSPNLLPAEHKAASQLLRLITK---- 1272
Query: 167 EQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAP 226
E+ + + VD+ ++ + + + L+ +E+A Q+T ++ + EEF+ A
Sbjct: 1273 EETDSNKVDLKKLLTPPLTPTKESIET-LSALEIAEQMTYLDHQIFISIASEEFLGQ-AW 1330
Query: 227 IHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQ 286
+ ++T A HI R FN +S LV ++I++ + R IE+
Sbjct: 1331 MKTDKATRA-------PHITLMTKR--------FNEVSQLVVSEIIRRSNMQARVGAIEK 1375
Query: 287 WVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLE 337
W L N+N ++ I +A S V RLKKTW + S Q + +L+
Sbjct: 1376 WAAVADISRVLHNYNGVLQICAAFTNSSVYRLKKTWEKVSKTTKQTIERLQ 1426
>UniRef50_UPI00015B5B51 Cluster: PREDICTED: similar to
ENSANGP00000025467; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000025467 - Nasonia
vitripennis
Length = 1384
Score = 55.6 bits (128), Expect = 2e-06
Identities = 26/96 (27%), Positives = 51/96 (53%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
L +A+ NR + V T++ R+++I+Q++ R+C NFNS+ AI+S L
Sbjct: 753 LSQFAELVNREMFWVVTEVCSEHNIVRRSKIIKQFIKIARQCKECKNFNSMFAIVSGLGH 812
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
V RL+ +W + + + L+ ++P+ N ++
Sbjct: 813 GAVSRLRASWEKLPSKYQRLFSDLQELMDPSRNMSK 848
>UniRef50_UPI0000DB6F3E Cluster: PREDICTED: similar to Gef26
CG9491-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to Gef26 CG9491-PA - Apis mellifera
Length = 1348
Score = 55.6 bits (128), Expect = 2e-06
Identities = 26/96 (27%), Positives = 51/96 (53%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
L +A+ NR + V T++ R+++I+Q++ R+C NFNS+ AI+S L
Sbjct: 754 LRQFAELVNREMFWVVTEVCSEHNLVRRSKIIKQFIKIARQCKECKNFNSMFAIVSGLGH 813
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
V RL+ +W + + + L+ ++P+ N ++
Sbjct: 814 GAVSRLRASWEKLPSKYQRLFSDLQELMDPSRNMSK 849
>UniRef50_A7S186 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 465
Score = 55.6 bits (128), Expect = 2e-06
Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 17/155 (10%)
Query: 170 EESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHP 229
++ L + S D + + P +A ++T+++ LS +G EE
Sbjct: 50 KDKLCQVVPTLSADGRNNVPFHLADIAPRAMAEEITMIDSEMLSAIGYEEV--------- 100
Query: 230 PQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVM 289
T +L ID + ++ D++N ++ + AT++L S+ RA VI + +
Sbjct: 101 --------TGGALMSIDKVKSPHVVQMIDFYNSIAAITATEVLVKEGSRDRAYVISRVIQ 152
Query: 290 TGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSR 324
EC + NFNS A++S L + RL KTW +
Sbjct: 153 MADECVDFNNFNSAKALMSGLRYVAITRLTKTWKK 187
>UniRef50_Q6P112 Cluster: Ral guanine nucleotide dissociation
stimulator-like 1; n=3; Clupeocephala|Rep: Ral guanine
nucleotide dissociation stimulator-like 1 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 804
Score = 55.6 bits (128), Expect = 2e-06
Identities = 28/79 (35%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Query: 260 FNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FN ++ V + IL+ ++ AR+I++W+ +EC NF+SL AI+SAL +P+ R
Sbjct: 321 FNAVTACVVSTILRQRQIRPHLCARIIQRWIDIAQECRIRKNFSSLRAIVSALQSNPLYR 380
Query: 318 LKKTWSRTSAVCGQQLRQL 336
LK+TW+ + Q +L
Sbjct: 381 LKRTWASVAKDSMQMFEEL 399
>UniRef50_Q6FVA6 Cluster: Candida glabrata strain CBS138 chromosome E
complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome E complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 1564
Score = 55.2 bits (127), Expect = 3e-06
Identities = 25/63 (39%), Positives = 41/63 (65%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N L+ V+ I+K + RA++I+ ++ + C L NF+S+ AI+SAL SP+ RLK+
Sbjct: 1329 NSLTNYVSFTIVKHADVQKRAKLIQYFITVAQHCKELNNFSSMTAIVSALYSSPIYRLKQ 1388
Query: 321 TWS 323
TW+
Sbjct: 1389 TWN 1391
>UniRef50_Q4PAN1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1559
Score = 54.8 bits (126), Expect = 4e-06
Identities = 37/117 (31%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
NR+S VA IL+ K RA +I+ ++ C L NF+ + AI+SAL+ +P+ RL++
Sbjct: 1449 NRISAWVAETILQQEDLKKRAALIKHFISIADRCRALNNFSGMWAIVSALSTAPIHRLRR 1508
Query: 321 TWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEKCALLSKHVSTQLASRRLTT 377
TW S LE + + N A E L ++T + SRR T+
Sbjct: 1509 TWDAVSQKYVLVFESLEQLMSASRNWANYR------EMIHKLKPPMATGIDSRRTTS 1559
>UniRef50_UPI00005A1264 Cluster: PREDICTED: similar to Ral guanine
nucleotide dissociation stimulator (RalGEF) (RalGDS);
n=3; Canis lupus familiaris|Rep: PREDICTED: similar to
Ral guanine nucleotide dissociation stimulator (RalGEF)
(RalGDS) - Canis familiaris
Length = 357
Score = 54.4 bits (125), Expect = 6e-06
Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVK--SKYRARVIEQWVMTGRECFNLGNFNSLMAII 307
T + A FN ++ V T L + ++ RA V+E W+ + C L N++SL AI+
Sbjct: 278 TCTVSATVTQFNNVANCVITTCLGNARMTARDRAEVVEHWIKVAKACRTLRNYSSLHAIL 337
Query: 308 SALNMSPVMRLKKTWSRTS 326
SAL + RLK TW++ S
Sbjct: 338 SALQSVSIHRLKNTWAKVS 356
>UniRef50_Q95V18 Cluster: Guanine nucleotide exchange factor; n=3;
Sophophora|Rep: Guanine nucleotide exchange factor -
Drosophila melanogaster (Fruit fly)
Length = 1573
Score = 54.4 bits (125), Expect = 6e-06
Identities = 26/96 (27%), Positives = 50/96 (52%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
L +A+ NR + V ++I R ++++Q++ R C NFNS+ AI+S L
Sbjct: 908 LSKFAELVNREMFWVVSEICAEHNIVRRMKIVKQFIKIARHCKECRNFNSMFAIVSGLGH 967
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
V RL++TW + + + L+ ++P+ N ++
Sbjct: 968 GAVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSK 1003
>UniRef50_Q55GH9 Cluster: RasGEF domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: RasGEF
domain-containing protein - Dictyostelium discoideum AX4
Length = 1172
Score = 54.4 bits (125), Expect = 6e-06
Identities = 29/99 (29%), Positives = 50/99 (50%)
Query: 247 TKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAI 306
T+ + N+ + + FN +S+ + T I+K K K R V+++ + L N+ M +
Sbjct: 974 TRLSPNIVRFIEHFNSVSFWLQTCIVKSGKIKERVAVLKKVIALADVFVQLNNYYGAMEV 1033
Query: 307 ISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
+S+L S V RL KTW + Q L+ L+ + P N
Sbjct: 1034 LSSLESSAVSRLHKTWEQVPQSSIQSLQSLQKLLSPQEN 1072
>UniRef50_Q555T3 Cluster: Ras guanine nucleotide exchange factor;
n=2; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor - Dictyostelium discoideum
AX4
Length = 929
Score = 54.4 bits (125), Expect = 6e-06
Identities = 24/71 (33%), Positives = 42/71 (59%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ + N+++ VAT+++ K R V+++++ C + NFN+LM +IS L+
Sbjct: 717 NIMSLITMSNKIANWVATEVVTTPHPKKRVEVLKRFISVAEHCKKINNFNTLMEVISGLS 776
Query: 312 MSPVMRLKKTW 322
S V RLK+TW
Sbjct: 777 NSAVSRLKETW 787
>UniRef50_Q9USU1 Cluster: Exchange factor Cdc25p-like; n=1;
Schizosaccharomyces pombe|Rep: Exchange factor
Cdc25p-like - Schizosaccharomyces pombe (Fission yeast)
Length = 987
Score = 54.4 bits (125), Expect = 6e-06
Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 3/84 (3%)
Query: 256 YADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPV 315
Y ++ N +Y + IL+ +K R VI ++ T +C +L NF++LM+I+SALN +P+
Sbjct: 793 YINFSNCFTYWIINCILEKKNTKARTAVISFFIQTAYKCLSLQNFSTLMSIVSALNSAPI 852
Query: 316 MRLKKTWSRTSA---VCGQQLRQL 336
RL + A +C LR++
Sbjct: 853 YRLHAAYKLVKAEDIICLSGLREI 876
>UniRef50_Q0UD52 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1132
Score = 54.4 bits (125), Expect = 6e-06
Identities = 34/96 (35%), Positives = 50/96 (52%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N++A N+L+ VA IL K R VI+ +VM +C L NF++L +IISAL
Sbjct: 916 NVKALILHSNQLTNWVAQMILTQQDVKRRVIVIKHFVMVADKCRQLNNFSTLTSIISALG 975
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
+P+ RL +TWS + L + + T N A
Sbjct: 976 TAPIHRLNRTWSAVNQRSMGVLESMRKLMGSTKNFA 1011
>UniRef50_UPI0001561664 Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial; n=2; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial - Equus
caballus
Length = 578
Score = 54.0 bits (124), Expect = 7e-06
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSA--VCGQQLRQ 335
RARV+E WV EC +LGNF+SL I+SAL + + L++TW ++ V ++ RQ
Sbjct: 284 RARVVELWVWVAEECRDLGNFSSLHTILSALQSTAITHLQETWGEVTSMLVTAERARQ 341
>UniRef50_Q5B8H1 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 468
Score = 54.0 bits (124), Expect = 7e-06
Identities = 28/95 (29%), Positives = 50/95 (52%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ A +FN+LS V +L K R +VI ++ C +L N++++++I+S L
Sbjct: 244 NVRALIQFFNQLSGWVGALVLAESDLKPRTQVIGHFINVANACHDLQNYSAVVSILSGLQ 303
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+PV RL +TW+ + +L L+ + NH
Sbjct: 304 SAPVYRLGRTWAMVTQRDCDKLEPLQAMMSSEQNH 338
>UniRef50_UPI0001561431 Cluster: PREDICTED: similar to pleckstrin
homology domain containing, family B (evectins) member
2; n=3; Equus caballus|Rep: PREDICTED: similar to
pleckstrin homology domain containing, family B
(evectins) member 2 - Equus caballus
Length = 593
Score = 53.6 bits (123), Expect = 1e-05
Identities = 23/47 (48%), Positives = 31/47 (65%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
RARV+E WV EC +LGNF+SL I+SAL + L++TW + S
Sbjct: 424 RARVVELWVWVAEECRDLGNFSSLHTILSALQSPAITHLQETWGQVS 470
>UniRef50_Q8MVR0 Cluster: Cyclic GMP-binding protein D; n=2;
Dictyostelium discoideum|Rep: Cyclic GMP-binding protein
D - Dictyostelium discoideum (Slime mold)
Length = 1312
Score = 53.6 bits (123), Expect = 1e-05
Identities = 28/94 (29%), Positives = 47/94 (50%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N++ WFNR+S V+T I+ + RA +IE ++ L N+N +M I+ +L+
Sbjct: 387 NIQNLTTWFNRISSWVSTKIISKETPEERAIIIEAFINIANFAKELKNYNCVMEILGSLH 446
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
S + RLK +W+ S + L + GN
Sbjct: 447 GSSISRLKSSWALLSQKTNDMFQILNNLMTTDGN 480
>UniRef50_Q1DXK6 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 848
Score = 53.6 bits (123), Expect = 1e-05
Identities = 30/95 (31%), Positives = 52/95 (54%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ FN L+Y A+ +L K+K+RA+ +E+++ + L N+NSL AII+ LN
Sbjct: 638 NVNRMIKQFNHLAYFAASMVLLRDKAKHRAQALEKFMNISLKLRQLYNYNSLGAIIAGLN 697
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+P+ RL +T + S +Q L + + +H
Sbjct: 698 GTPIYRLAQTQALVSHSVKKQFMSLVILMGTQKSH 732
>UniRef50_A7TSP6 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1371
Score = 53.6 bits (123), Expect = 1e-05
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 198 VELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYA 257
+ +A QLT++E L + +E + + I P +TS + I ++ ++
Sbjct: 1129 ISIAKQLTLIEKEILLEIDWQEMLDLKSTIEGPHATSWLQLLIQNENLS-----GIDLAI 1183
Query: 258 DWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FN + + ++I+ +K + VI++++ C + N+NS+M II ALN S + +
Sbjct: 1184 SRFNLVVDWIVSEIVLTTDTKLKRNVIQRYIHVADHCKRMQNYNSMMQIILALNSSTIQK 1243
Query: 318 LKKTW 322
+TW
Sbjct: 1244 YIETW 1248
>UniRef50_Q17MY4 Cluster: Ral guanine nucleotide exchange factor,
putative; n=2; Endopterygota|Rep: Ral guanine nucleotide
exchange factor, putative - Aedes aegypti (Yellowfever
mosquito)
Length = 717
Score = 53.2 bits (122), Expect = 1e-05
Identities = 62/237 (26%), Positives = 96/237 (40%), Gaps = 15/237 (6%)
Query: 93 AEVKDLVEKELNDMI--ALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRV 150
AE+ L + LND LV VL W FP D+ + + L+ ++R + + +
Sbjct: 113 AELALLPAESLNDQHKKTLVSVLHVWLDGFPEDWDTENLQRLLAFTSKR-----LPNSEI 167
Query: 151 EMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILTLGLT--PVELANQLTIVE 208
+ L+ L++Y + DQ G LT P L N
Sbjct: 168 HVKALHSCLMKYTNRLDKYSRIPPPLPWSDLTDQFG-GLCLTPAFRGPPSHLLNSYRFPN 226
Query: 209 LHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVA 268
+ F E+ + + C +I + +C L A FN +S+ V
Sbjct: 227 IPVKHFA--EQLTRMDMELFKRLIPHQCLGAIWSNRDKHECGSVL-ATVTQFNAVSFRVI 283
Query: 269 TDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
+ IL +K + RA +I W+ +E L NF+SL AIIS L + V RL KTW+
Sbjct: 284 SSILIEPRLKPQERALLISTWIDIAQELRLLKNFSSLKAIISGLQSNAVYRLSKTWA 340
>UniRef50_A7TRY3 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1548
Score = 53.2 bits (122), Expect = 1e-05
Identities = 31/102 (30%), Positives = 49/102 (48%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
+ D + N+ + N+ + V+ I+ K RA+ ++ ++ C L NF+ +
Sbjct: 1302 YCDLGGSENISNFISSANQFTNYVSHSIVITQDVKKRAKRVQYFISVANHCRLLNNFSVM 1361
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
AIISAL SPV RLKKTW L+ L ++ T N
Sbjct: 1362 TAIISALYSSPVYRLKKTWQLIPKEYNDILKNLNTLMDSTKN 1403
>UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor 3;
n=33; Euteleostomi|Rep: Rap guanine nucleotide exchange
factor 3 - Homo sapiens (Human)
Length = 881
Score = 53.2 bits (122), Expect = 1e-05
Identities = 30/103 (29%), Positives = 48/103 (46%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H+ T NLE + FN L Y VAT++ RA+++ +++ N NS
Sbjct: 653 HLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSF 712
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A++ L+ S + RL TW R + LE ++P+ NH
Sbjct: 713 FAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNH 755
>UniRef50_UPI0000E1F333 Cluster: PREDICTED: RAS guanyl releasing
protein 3 (calcium and DAG-regulated) isoform 1; n=2;
Catarrhini|Rep: PREDICTED: RAS guanyl releasing protein
3 (calcium and DAG-regulated) isoform 1 - Pan
troglodytes
Length = 555
Score = 52.8 bits (121), Expect = 2e-05
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 24/174 (13%)
Query: 176 ITQVSSLDQLSQGDILTLGLTPVELANQLTIVE---LHRLSFVGPEEFVQTFAPIHPPQS 232
+TQ + + + +L L P+ELA LT +E R+SF + +V IH
Sbjct: 35 VTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV-----IH---- 85
Query: 233 TSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGR 292
C ++ T LE FN +S V +L + RA VI +++ +
Sbjct: 86 --GC--------LENNPT--LERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAK 133
Query: 293 ECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S+ + ++ V GN+
Sbjct: 134 KLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNY 187
>UniRef50_Q9UL65 Cluster: RAS guanyl-releasing protein 2; n=35;
Euteleostomi|Rep: RAS guanyl-releasing protein 2 - Homo
sapiens (Human)
Length = 671
Score = 52.8 bits (121), Expect = 2e-05
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 231 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 290
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 291 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 348
>UniRef50_UPI00015B534D Cluster: PREDICTED: similar to CG5522-PD;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG5522-PD - Nasonia vitripennis
Length = 607
Score = 52.4 bits (120), Expect = 2e-05
Identities = 22/72 (30%), Positives = 41/72 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ ++ FN S+ +IL K R+ ++ ++ ++ ++L N +SL AIIS L+
Sbjct: 163 NVVSFTRRFNHASFWTVQEILNAPTPKQRSEILAHFIRVAKKLYDLNNLHSLFAIISGLH 222
Query: 312 MSPVMRLKKTWS 323
+ + RL KTW+
Sbjct: 223 SASIYRLNKTWA 234
>UniRef50_UPI00015617B8 Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial; n=1; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial - Equus
caballus
Length = 557
Score = 52.4 bits (120), Expect = 2e-05
Identities = 23/47 (48%), Positives = 29/47 (61%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
RARV+E W+ EC LGNF SL I+SAL + RL+ TW + S
Sbjct: 243 RARVVELWIRVAEECRGLGNFCSLHTILSALQSPAIARLQDTWGQVS 289
>UniRef50_Q55AB0 Cluster: Ras guanine nucleotide exchange factor; n=2;
Dictyostelium discoideum|Rep: Ras guanine nucleotide
exchange factor - Dictyostelium discoideum AX4
Length = 1556
Score = 52.4 bits (120), Expect = 2e-05
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
+ L E+A QLT++E + EF+ QS + KT H+ N
Sbjct: 1314 ISLPAEEIAKQLTLIEFEIFGKIQSSEFLN--------QSWAKEKT----FHL----APN 1357
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A D FN ++ V T ILK K + R +++ + + + + NF++LMAI+S LN
Sbjct: 1358 IRASIDRFNTVTKWVCTIILKEEKIRTRTKIMSKLLKVAKNLRSYSNFHTLMAILSGLNE 1417
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ RLK T + +L+ + GNH
Sbjct: 1418 IHIYRLKFTQQELKPKIQKISSELQTLMSVEGNH 1451
>UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor 4;
n=53; Coelomata|Rep: Rap guanine nucleotide exchange
factor 4 - Homo sapiens (Human)
Length = 1011
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/103 (26%), Positives = 49/103 (47%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H K T NL+ + FN + + V T+I + R +++++++ C N NS
Sbjct: 804 HNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 863
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
AI+ L+ V RL TW + + + + E ++P+ NH
Sbjct: 864 FAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNH 906
>UniRef50_O15211 Cluster: Ral guanine nucleotide dissociation
stimulator-like 2; n=26; Euteleostomi|Rep: Ral guanine
nucleotide dissociation stimulator-like 2 - Homo sapiens
(Human)
Length = 777
Score = 52.4 bits (120), Expect = 2e-05
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 320 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 374
>UniRef50_UPI00004996A3 Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 578
Score = 52.0 bits (119), Expect = 3e-05
Identities = 33/100 (33%), Positives = 48/100 (48%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T N+ A N++SY+V IL VK KYR IE ++ L NF+ AI++A
Sbjct: 340 TPNIVAMMQLTNKISYIVQNIILSFVKLKYRIFAIEFFIKVAEYLKKLNNFDGFKAILAA 399
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
L+ S + RLK T S + L + + V N +L
Sbjct: 400 LDSSAIYRLKDTKDGLSEESIKLLTEFQSIVNYESNFKKL 439
>UniRef50_Q54YQ2 Cluster: Ras guanine nucleotide exchange factor;
n=4; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor - Dictyostelium discoideum
AX4
Length = 824
Score = 52.0 bits (119), Expect = 3e-05
Identities = 29/63 (46%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECF-NLGNFNSLMAIISALNMSPVMRL 318
FN +S AT IL K K RAR++ +++ C +L NFN+ MAI+S LN S V RL
Sbjct: 633 FNEISQWTATSILSWPKVKDRARIMGKFIKIAEYCMKHLNNFNTSMAILSGLNASSVHRL 692
Query: 319 KKT 321
K T
Sbjct: 693 KFT 695
>UniRef50_Q6BNH1 Cluster: Debaryomyces hansenii chromosome E of strain
CBS767 of Debaryomyces hansenii; n=3;
Saccharomycetaceae|Rep: Debaryomyces hansenii chromosome
E of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 1550
Score = 52.0 bits (119), Expect = 3e-05
Identities = 43/154 (27%), Positives = 66/154 (42%), Gaps = 16/154 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +ELA QLT++E H + P+E + Q+ +A + + L N
Sbjct: 1262 LDFNGLELAKQLTLIESHIFCSIKPDELLN--------QNFTAKRAHLKL-------APN 1306
Query: 253 LEAYADWFNRLSYLVATDILKG-VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+ + N LS V IL+ + K R +I+ W+ C L NFNSL +II++L
Sbjct: 1307 IRQSLLFTNCLSGYVLESILQPKINQKMRVNIIKTWLKVAISCLYLRNFNSLASIITSLQ 1366
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
+ RL K W S + L + P N
Sbjct: 1367 SHLITRLAKIWVDLSDKYKELYEYLSGIIHPQKN 1400
>UniRef50_Q5KPL7 Cluster: Ras guanyl-nucleotide exchange factor,
putative; n=2; Filobasidiella neoformans|Rep: Ras
guanyl-nucleotide exchange factor, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 1023
Score = 52.0 bits (119), Expect = 3e-05
Identities = 25/61 (40%), Positives = 40/61 (65%)
Query: 258 DWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
++FN LS ++T +L K+K+RARVIE+++ + L N++SL A+IS L + V R
Sbjct: 811 NFFNHLSRWISTIVLASSKAKHRARVIERFIFIAHQLRRLNNYDSLYAVISGLREASVHR 870
Query: 318 L 318
L
Sbjct: 871 L 871
>UniRef50_UPI000155FBAC Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial; n=1; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial - Equus
caballus
Length = 514
Score = 51.6 bits (118), Expect = 4e-05
Identities = 23/47 (48%), Positives = 29/47 (61%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
RARV+E W+ EC LGNF SL I+SAL + RL+ TW + S
Sbjct: 340 RARVVELWISVADECRGLGNFCSLHTILSALQSPAIARLQDTWGQVS 386
>UniRef50_UPI0000E485ED Cluster: PREDICTED: similar to Ral guanine
nucleotide dissociation stimulator,-like 1, partial;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Ral guanine nucleotide dissociation
stimulator,-like 1, partial - Strongylocentrotus
purpuratus
Length = 299
Score = 51.6 bits (118), Expect = 4e-05
Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 255 AYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
A + FN ++ V + IL K ++ R +I +W+ + C L NF++L AIISAL
Sbjct: 78 ATVNQFNDITMKVMSTILEEKSLRPMTRGLIITKWIDVAQSCRELKNFSALKAIISALQS 137
Query: 313 SPVMRLKKTWS 323
P+ RL++ WS
Sbjct: 138 HPIHRLRRAWS 148
>UniRef50_Q55EC7 Cluster: RasGEF domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: RasGEF
domain-containing protein - Dictyostelium discoideum AX4
Length = 960
Score = 51.6 bits (118), Expect = 4e-05
Identities = 34/150 (22%), Positives = 64/150 (42%), Gaps = 2/150 (1%)
Query: 199 ELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYAD 258
ELA Q+TI+ + + EF++ +ST+ S ++ N+ +
Sbjct: 715 ELARQITIINSFYFNRIKAREFIEYIWEKCGEESTTTPYVGTSF--VEVVPAENIHKFVR 772
Query: 259 WFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
N L+ V+T+ILK K + R IE+++ +C ++ ++ +I+ L + RL
Sbjct: 773 KCNNLARFVSTEILKQTKLQKRVATIERFIEAAEKCLANNDYAAVFSIVEPLVDQSIERL 832
Query: 319 KKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
TW S L+ V +H +
Sbjct: 833 SDTWRNVSQRNLATFEHLKSIVSKENDHKK 862
>UniRef50_Q92565 Cluster: Rap guanine nucleotide exchange factor 5;
n=35; Euteleostomi|Rep: Rap guanine nucleotide exchange
factor 5 - Homo sapiens (Human)
Length = 580
Score = 51.6 bits (118), Expect = 4e-05
Identities = 28/97 (28%), Positives = 46/97 (47%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NL N + VAT+IL + R +++++++ C N NS AI+
Sbjct: 383 TANLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMG 442
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
LN + V RL +TW + + +LE +P+ NH
Sbjct: 443 LNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNH 479
>UniRef50_A7RH05 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 2289
Score = 51.2 bits (117), Expect = 5e-05
Identities = 30/99 (30%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
++D++ E AD FN+LS V IL + RA++ ++ T ++C L NFN++
Sbjct: 2022 NLDSQPRLLCERVADRFNQLSTWVVASILTEESVEKRAQMFINFIETAKQCLKLRNFNAV 2081
Query: 304 MAI-ISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVE 341
MAI ++AL S + RL +T +Q ++E+ ++
Sbjct: 2082 MAIVVAALGSSSIRRLARTKQLVPKEFLEQCAKIEMLMD 2120
>UniRef50_UPI00015B4D6B Cluster: PREDICTED: similar to ral guanine
nucleotide exchange factor, putative; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to ral guanine
nucleotide exchange factor, putative - Nasonia
vitripennis
Length = 849
Score = 50.8 bits (116), Expect = 7e-05
Identities = 26/62 (41%), Positives = 36/62 (58%)
Query: 276 KSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQ 335
K + RAR+IE W+ +E L NF+SL AI+S L +PV RL+K W + R+
Sbjct: 438 KPQERARIIETWIDIAQELRILKNFSSLKAIVSGLQSNPVYRLEKCWQCVPREKYEVFRE 497
Query: 336 LE 337
LE
Sbjct: 498 LE 499
>UniRef50_UPI00005A5919 Cluster: PREDICTED: similar to Ral guanine
nucleotide dissociation stimulator (RalGEF) (RalGDS);
n=5; Canis lupus familiaris|Rep: PREDICTED: similar to
Ral guanine nucleotide dissociation stimulator (RalGEF)
(RalGDS) - Canis familiaris
Length = 286
Score = 50.8 bits (116), Expect = 7e-05
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAII 307
T + A FN ++ V T L + ++ RA V+E W+ + C L N++S+ AI+
Sbjct: 207 TCTVSATISQFNNVANCVITTCLGNAHMTARDRAVVVEHWIKVAKACQALRNYSSMHAIL 266
Query: 308 SALNMSPVMRLKKTWSRTS 326
SAL + RLK TW++ S
Sbjct: 267 SALQSVSIHRLKNTWAKVS 285
>UniRef50_UPI0000ECA662 Cluster: Rap guanine nucleotide exchange
factor 1 (Guanine nucleotide-releasing factor 2) (C3G
protein) (CRK SH3-binding GNRP).; n=1; Gallus gallus|Rep:
Rap guanine nucleotide exchange factor 1 (Guanine
nucleotide-releasing factor 2) (C3G protein) (CRK
SH3-binding GNRP). - Gallus gallus
Length = 1230
Score = 50.8 bits (116), Expect = 7e-05
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 1031 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 1090
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 1091 SAPIRRLE--WQKQTS 1104
>UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange
factor 3 (cAMP-regulated guanine nucleotide exchange
factor I) (cAMP-GEFI) (Exchange factor directly
activated by cAMP 1) (Epac 1) (Rap1
guanine-nucleotide-exchange factor directly activated by
cAMP).; n=1; Gallus gallus|Rep: Rap guanine nucleotide
exchange factor 3 (cAMP-regulated guanine nucleotide
exchange factor I) (cAMP-GEFI) (Exchange factor directly
activated by cAMP 1) (Epac 1) (Rap1
guanine-nucleotide-exchange factor directly activated by
cAMP). - Gallus gallus
Length = 766
Score = 50.8 bits (116), Expect = 7e-05
Identities = 29/97 (29%), Positives = 47/97 (48%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NLE FN L Y VAT++ + RA+++ +++ N NS A++
Sbjct: 582 TANLERMMRRFNELQYWVATELCLCPELGRRAQLLRKFIKLAAHLKEQKNLNSFFAVMFG 641
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
++ + V RL KTW R + LE ++P+ NH
Sbjct: 642 VSNTAVSRLAKTWERLPHKIRKLHAALERMLDPSWNH 678
>UniRef50_Q9U4U5 Cluster: Ral guanine nucleotide exchange factor 2;
n=5; Diptera|Rep: Ral guanine nucleotide exchange factor
2 - Drosophila melanogaster (Fruit fly)
Length = 954
Score = 50.8 bits (116), Expect = 7e-05
Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 30/241 (12%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLT---- 164
LV L W FP D+ +D + ++ T+R + +++ LE+L+ +
Sbjct: 329 LVSALHVWLDGFPEDWHEDNLQQILAFATKRLKRSDLH---IKVLNRLERLIKQSLYGNG 385
Query: 165 -ALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVEL----HRLSFVGPEE 219
E + + Q+ Q I T + +L +Q + L H + GP
Sbjct: 386 GGSGGSENNGHSWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPTH 445
Query: 220 FVQTFAPIHPP-----QSTSACKTSISLHHIDTKC------------TRNLEAYADWFNR 262
F+Q F H P + + T + I +C + + A + FN
Sbjct: 446 FLQAFRFPHVPVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSGGSETVVATINQFNA 505
Query: 263 LSYLVATDIL-KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKT 321
+ + V + IL +K + RA I +W+ +E L NF+SL AIISALN + + RL K
Sbjct: 506 VLFRVVSSILIDRLKPQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKI 565
Query: 322 W 322
W
Sbjct: 566 W 566
>UniRef50_Q5C2U2 Cluster: SJCHGC07188 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07188 protein - Schistosoma
japonicum (Blood fluke)
Length = 191
Score = 50.8 bits (116), Expect = 7e-05
Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 16/129 (12%)
Query: 195 LTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLE 254
+TP + A Q+T++EL + EEF ++ K + H+ N+
Sbjct: 33 VTPEDFAKQITLIELSFFKAIRREEF-------------ASLKWNGREKHLYAP---NIV 76
Query: 255 AYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSP 314
A WFN++++ V +ILK R ++ ++ ++ + N S M+IISAL +
Sbjct: 77 ASTRWFNQINFWVQKEILKYSCVSKRTEMLSFFIKISKKLVEINNLYSAMSIISALQVEC 136
Query: 315 VMRLKKTWS 323
+ RL+ TWS
Sbjct: 137 IYRLRHTWS 145
>UniRef50_Q55FD8 Cluster: RasGEF domain-containing protein; n=2;
Eukaryota|Rep: RasGEF domain-containing protein -
Dictyostelium discoideum AX4
Length = 1982
Score = 50.8 bits (116), Expect = 7e-05
Identities = 32/86 (37%), Positives = 45/86 (52%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ + FN++S V+ I+ K + RA V + V + L N++ LMAIIS LN
Sbjct: 1784 NIMSVVGLFNKISNWVSFTIVNQPKLRDRAVVYGKMVKIANAFYELRNYHLLMAIISGLN 1843
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLE 337
SPV+RLK T + S L LE
Sbjct: 1844 ASPVLRLKYTKGKLSKNLKDNLDTLE 1869
>UniRef50_Q5JUE6 Cluster: Rap guanine nucleotide exchange factor
(GEF) 1; n=12; Euteleostomi|Rep: Rap guanine nucleotide
exchange factor (GEF) 1 - Homo sapiens (Human)
Length = 1023
Score = 50.8 bits (116), Expect = 7e-05
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 824 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 883
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 884 SAPIRRLE--WQKQTS 897
>UniRef50_Q2H8X6 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 1160
Score = 50.8 bits (116), Expect = 7e-05
Identities = 20/42 (47%), Positives = 31/42 (73%)
Query: 283 VIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSR 324
V +QW+ G++C L NF++L +IISAL +P+ RLK+TW +
Sbjct: 980 VCQQWLTVGQKCRVLNNFSTLTSIISALGTAPIARLKRTWDQ 1021
>UniRef50_Q13905 Cluster: Rap guanine nucleotide exchange factor 1;
n=26; Tetrapoda|Rep: Rap guanine nucleotide exchange
factor 1 - Homo sapiens (Human)
Length = 1077
Score = 50.8 bits (116), Expect = 7e-05
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 878 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 937
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 938 SAPIRRLE--WQKQTS 951
>UniRef50_UPI00015616C9 Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator; n=16; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator - Equus caballus
Length = 698
Score = 50.4 bits (115), Expect = 9e-05
Identities = 22/47 (46%), Positives = 28/47 (59%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
RARV+E W+ EC LGNF SL I+SAL + L+ TW + S
Sbjct: 319 RARVVELWIRVAEECRGLGNFCSLHTILSALQSPAIAHLQDTWGQVS 365
>UniRef50_Q16I23 Cluster: Guanine-nucleotide exchange factor c3g; n=1;
Aedes aegypti|Rep: Guanine-nucleotide exchange factor c3g
- Aedes aegypti (Yellowfever mosquito)
Length = 1131
Score = 50.4 bits (115), Expect = 9e-05
Identities = 23/74 (31%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN++SY + IL+ +K R + + +++ + + N+NS +A++SAL+
Sbjct: 1024 NLTTFTEHFNKMSYWARSQILRQEDAKDREKHVIKFIKIMKHLRKINNYNSYLALLSALD 1083
Query: 312 MSPVMRLKKTWSRT 325
+P+ RL+ W RT
Sbjct: 1084 SAPIRRLE--WHRT 1095
>UniRef50_A7S271 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 422
Score = 50.4 bits (115), Expect = 9e-05
Identities = 30/98 (30%), Positives = 46/98 (46%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T LE Y FN LS + +L ++ RA+ IE++ + L NFN L+A+
Sbjct: 46 TTYLERYVSMFNGLSKWIQAMVLNHTSAEDRAKCIEKFQKVAQSLKELQNFNGLLAVTGG 105
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
LN S + RL +T S C + + L + N+A
Sbjct: 106 LNNSVLSRLLQTREYVSKDCKEYMNLLTEFLSSENNYA 143
>UniRef50_Q4P4A0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1762
Score = 50.4 bits (115), Expect = 9e-05
Identities = 33/97 (34%), Positives = 45/97 (46%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+EA FN S VA++++ RA VI + + +C+ NF SL II LN
Sbjct: 1503 VEAIVARFNLTSNWVASEVVLTQNIDERAAVISKLIRIAWKCYLQSNFASLAQIIFGLNT 1562
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
V RL++TWSR + R L V P N L
Sbjct: 1563 PWVQRLRRTWSRVGYFETRMWRDLNSFVGPRHNFRHL 1599
>UniRef50_Q6FVQ6 Cluster: Candida glabrata strain CBS138 chromosome D
complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome D complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 1308
Score = 50.0 bits (114), Expect = 1e-04
Identities = 27/96 (28%), Positives = 50/96 (52%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
++N+ + + N ++ V+ IL+ + R + I ++ R + + NF+S+ AIIS
Sbjct: 1031 SKNISEFISFANSITKYVSYKILQYDTAAKRGQAIGYFIKVARISYEINNFSSMTAIISG 1090
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
+ SPV RL ++W S LR+L+ + T N
Sbjct: 1091 IYASPVNRLHESWKLVSRELQNTLRELDDLMISTKN 1126
>UniRef50_A2Q880 Cluster: Contig An01c0100, complete genome; n=10;
Trichocomaceae|Rep: Contig An01c0100, complete genome -
Aspergillus niger
Length = 1116
Score = 50.0 bits (114), Expect = 1e-04
Identities = 24/62 (38%), Positives = 41/62 (66%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +++ VA+ IL K K+RA+ +E+++ + L N+NSL A+I+ +N +PV RL
Sbjct: 711 FNHVAFFVASVILLRDKPKHRAKALEKFMNIALKLRRLNNYNSLGAVIAGINGTPVHRLS 770
Query: 320 KT 321
+T
Sbjct: 771 QT 772
>UniRef50_UPI0000F20A79 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Danio rerio|Rep: PREDICTED: hypothetical
protein, partial - Danio rerio
Length = 217
Score = 49.6 bits (113), Expect = 2e-04
Identities = 27/91 (29%), Positives = 45/91 (49%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
LE + FN +S + +L ++ RA VI +++ L NFN+LMA++ L+
Sbjct: 66 LERFITLFNSVSQWIQIMVLSKPTAQQRATVISEFIKVAERLLQLQNFNTLMAVVGGLSN 125
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPT 343
S + RLK T + S+ ++ E C T
Sbjct: 126 SSIARLKNTQALISSDTRKRSEYRESCSPET 156
>UniRef50_UPI000156180A Cluster: PREDICTED: similar to Ral guanine
nucleotide dissociation stimulator; n=7; Equus
caballus|Rep: PREDICTED: similar to Ral guanine
nucleotide dissociation stimulator - Equus caballus
Length = 738
Score = 49.2 bits (112), Expect = 2e-04
Identities = 21/53 (39%), Positives = 31/53 (58%)
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
G+ ++ RARV+E W+ C L NF+S I+SAL + LK+TW + S
Sbjct: 516 GMTAQERARVVELWIQVAEGCRGLRNFSSFHRILSALQSPAIKHLKETWGQVS 568
>UniRef50_UPI0001561381 Cluster: PREDICTED: similar to guanine
nucleotide dissociation stimulator; n=1; Equus
caballus|Rep: PREDICTED: similar to guanine nucleotide
dissociation stimulator - Equus caballus
Length = 555
Score = 49.2 bits (112), Expect = 2e-04
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSA 327
G+ ++ RARV+E W+ C L NF+S I+SAL + ++K+TW + S+
Sbjct: 280 GMAAQERARVVELWIQVAEGCRGLRNFSSFHMILSALQSPAIKQIKETWGQVSS 333
>UniRef50_UPI000049846E Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 464
Score = 49.2 bits (112), Expect = 2e-04
Identities = 47/235 (20%), Positives = 96/235 (40%), Gaps = 28/235 (11%)
Query: 113 LRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEES 172
++ WT + PYDF D ++ + + Q+ ++ + ++ + + L E+ E S
Sbjct: 156 MKIWTDLLPYDFHDKEILGAIETFLQKYQSQFVGIAQIRKMIQAAQSIPHLPTFERIENS 215
Query: 173 LVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQS 232
+ + + +L T + QL++ EL + + ++F+
Sbjct: 216 NGE-EKTKPVKEL----------TAETIVGQLSLYELTLFTGIEMKDFL----------- 253
Query: 233 TSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGR 292
+ T + +C R E + + FN ++ V+ IL+ RA +I +++ +
Sbjct: 254 -GSAWTKKDKYE---RCPRLCE-FLEHFNAVTNWVSYSILQESDINARANLISKFIDVAK 308
Query: 293 ECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
+ NF S LN S + RL KTW Q++ L +PT ++A
Sbjct: 309 IMYEQMNFTGFFEFYSGLNSSAISRLTKTWELVEN-AAQRMDPLRKAADPTRSYA 362
>UniRef50_Q7PSV2 Cluster: ENSANGP00000005326; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000005326 - Anopheles gambiae
str. PEST
Length = 1262
Score = 49.2 bits (112), Expect = 2e-04
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 2/74 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN++SY T IL +K R + + +++ + + N+NS +A++SAL+
Sbjct: 1067 NLTRFTEHFNKMSYWARTQILSQNDAKDREKHVIKFIKIMKHLRKINNYNSYLALLSALD 1126
Query: 312 MSPVMRLKKTWSRT 325
+P+ RL+ W +T
Sbjct: 1127 SAPIRRLE--WHKT 1138
>UniRef50_Q2GVZ4 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 959
Score = 49.2 bits (112), Expect = 2e-04
Identities = 30/110 (27%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Query: 240 ISLHHIDTKCTRNLE---AYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFN 296
+SL H + RNL+ FN +++ V+ IL K+K+RA +E++++ +
Sbjct: 732 VSLSHDQKEKCRNLKNVNRMVSHFNHVAHWVSNMILIRDKAKHRAPCLEKFIVVAQRLRQ 791
Query: 297 LGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ N+N L A+++ +N S + RL +T + SA ++ L L + +H
Sbjct: 792 MNNYNGLAAVLAGINGSAIHRLAQTRAAISAEAQKRHAGLALLMGTQKSH 841
>UniRef50_Q6CY10 Cluster: Guanine nucleotide exchange factor LTE1;
n=1; Kluyveromyces lactis|Rep: Guanine nucleotide
exchange factor LTE1 - Kluyveromyces lactis (Yeast)
(Candida sphaerica)
Length = 1366
Score = 49.2 bits (112), Expect = 2e-04
Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 11/144 (7%)
Query: 182 LDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSI- 240
+D L Q L +ANQLT++E LS V ++ + PQ TS + +
Sbjct: 1107 IDNLEQHIPFILMYDSKSVANQLTLIEKEILSEVDWKDLLDLTMSEQLPQFTSWLQLLVQ 1166
Query: 241 --SLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLG 298
+L ID R DW +S +V T ++ R I++++ C L
Sbjct: 1167 NENLSGIDLAIAR-FNLTVDWI--ISEIVMTQDIR-----LRRNTIQRFIHIAEHCKELQ 1218
Query: 299 NFNSLMAIISALNMSPVMRLKKTW 322
N+N+LM II ALN V + +TW
Sbjct: 1219 NYNTLMEIILALNSIVVQKFTETW 1242
>UniRef50_UPI000156180E Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator; n=2; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator - Equus caballus
Length = 527
Score = 48.8 bits (111), Expect = 3e-04
Identities = 21/53 (39%), Positives = 31/53 (58%)
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
G ++ RARV+E W+ + C L NF+S I+SAL + + LK TW + S
Sbjct: 334 GTTAQERARVVELWIHVAKGCRGLRNFSSFHMILSALQIPAIKHLKDTWGQVS 386
>UniRef50_Q55AH0 Cluster: Ras guanine nucleotide exchange factor;
n=2; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor - Dictyostelium discoideum
AX4
Length = 1043
Score = 48.8 bits (111), Expect = 3e-04
Identities = 27/76 (35%), Positives = 43/76 (56%)
Query: 262 RLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKT 321
+ S+ VA IL K + R ++ E++ G+ + NFNSLM + + LN++ V RLKKT
Sbjct: 853 QFSFWVAYVILMEPKKEKRIKIFEKFCEVGKYLLKMNNFNSLMGLNAGLNLTCVHRLKKT 912
Query: 322 WSRTSAVCGQQLRQLE 337
+ S+ L +LE
Sbjct: 913 KKKLSSSAISILTELE 928
>UniRef50_A7S390 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 850
Score = 48.8 bits (111), Expect = 3e-04
Identities = 27/92 (29%), Positives = 45/92 (48%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + NR ++ V T+I R ++I+ ++ + C + N NS AIIS L
Sbjct: 601 NLAKFEETVNRETFWVVTEICGESNVVKRMKLIKHFIKIAKYCKDCKNINSAFAIISGLG 660
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPT 343
+ V RLK TW + + LE ++P+
Sbjct: 661 HTAVKRLKNTWEKLPNRYYKMYEDLENLMDPS 692
>UniRef50_A2DHX3 Cluster: RasGEF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: RasGEF domain containing
protein - Trichomonas vaginalis G3
Length = 914
Score = 48.8 bits (111), Expect = 3e-04
Identities = 54/219 (24%), Positives = 90/219 (41%), Gaps = 24/219 (10%)
Query: 113 LRQWTSMFPYDF----RDDRVMALVRSITQRCAA-EHMESVRVEMSTTLEKLLD--KLTA 165
L++W +MFP DF D + + I + C A E ES+ + E+L +L
Sbjct: 569 LQKWVAMFPEDFVTLVDDGSLKGIYGYIREFCNADETKESIDSVLKKPKEQLRTSKELKP 628
Query: 166 LEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFA 225
+E+ E+ + + L + +AN + EL + + +EFV
Sbjct: 629 VEKVEKKFGTAEYLDDIKIEPLKHTLAFTADSLTIANHIMYHELAIFNNINYKEFV---- 684
Query: 226 PIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKS--KYRARV 283
AC + + NL A FN+LS + ++ K K A +
Sbjct: 685 ---------ACGWANKTN--PEAIAPNLVTIAKRFNKLSQYIQYSLVHYTKRDPKATAII 733
Query: 284 IEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTW 322
+ QW++ ++C + NF+ L I SAL+ PV RL W
Sbjct: 734 MAQWILVMQKCSEIRNFHGLFVIDSALSAPPVTRLHGCW 772
>UniRef50_Q75AF6 Cluster: ADL038Wp; n=1; Eremothecium gossypii|Rep:
ADL038Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 1509
Score = 48.8 bits (111), Expect = 3e-04
Identities = 23/72 (31%), Positives = 41/72 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ ++ N L+ V+ I+K K R ++++ ++ C L NF+S+ AI SA+
Sbjct: 1273 NISSFIQNSNHLTNYVSYMIVKQTDLKRRVQIVQYFIDVAETCRALNNFSSMTAITSAML 1332
Query: 312 MSPVMRLKKTWS 323
S + RLK+TW+
Sbjct: 1333 SSSIYRLKRTWA 1344
>UniRef50_Q54H48 Cluster: Ras guanine nucleotide exchange factor;
n=2; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor - Dictyostelium discoideum
AX4
Length = 668
Score = 48.4 bits (110), Expect = 4e-04
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + +++IL K R + ++ + C LGN+N+ AI+ LN S + RLK
Sbjct: 478 FNEWARWTSSEILSKEKLVERVVTLSFFIDLAKSCVELGNYNAANAIVGGLNHSSISRLK 537
Query: 320 KTWSRTSAVCGQQLRQL 336
TW R S Q +L
Sbjct: 538 LTWERLSTKVTQDYDRL 554
>UniRef50_Q29IL8 Cluster: GA16131-PA; n=1; Drosophila
pseudoobscura|Rep: GA16131-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 1196
Score = 48.0 bits (109), Expect = 5e-04
Identities = 23/77 (29%), Positives = 44/77 (57%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN++SY + IL+ +K R + + +++ + + N+NS +A++SAL+
Sbjct: 1002 NLNKFTEHFNKMSYWARSKILRLHDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALD 1061
Query: 312 MSPVMRLKKTWSRTSAV 328
P+ RL+ S T V
Sbjct: 1062 SGPIRRLEWQKSITEEV 1078
>UniRef50_Q19770 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 654
Score = 48.0 bits (109), Expect = 5e-04
Identities = 28/84 (33%), Positives = 43/84 (51%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
LE FN LS V IL K RA ++ ++V + + NFN+LM+++ +
Sbjct: 193 LERSISVFNNLSNWVQCMILNKTTPKERAEILVKFVHVAKHLRKINNFNTLMSVVGGITH 252
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQL 336
S V RL KT++ S ++L QL
Sbjct: 253 SSVARLAKTYAVLSNDIKKELTQL 276
>UniRef50_A7RT22 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1437
Score = 48.0 bits (109), Expect = 5e-04
Identities = 22/73 (30%), Positives = 39/73 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
++ A +++NRLS + +IL +K RA++I + + +C NFNS A++ +
Sbjct: 1190 HVHAMIEFYNRLSAICVANILSKESAKDRAKIITKIIKIAEKCAQFNNFNSCKALLISFR 1249
Query: 312 MSPVMRLKKTWSR 324
V RL TW +
Sbjct: 1250 FHVVSRLCDTWKQ 1262
>UniRef50_UPI0000499F54 Cluster: Ras guanine nucleotide exchange
factor; n=2; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 493
Score = 47.6 bits (108), Expect = 6e-04
Identities = 27/73 (36%), Positives = 34/73 (46%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NL RL V T IL + YRA I ++ E L NF + A+ SA
Sbjct: 268 TPNLIRLVRSSKRLFSFVQTSILVEKRVAYRALFIHYFLQVAEEMKKLNNFEGMKAVFSA 327
Query: 310 LNMSPVMRLKKTW 322
L +P+ RLK TW
Sbjct: 328 LESTPIYRLKDTW 340
>UniRef50_Q6C3H8 Cluster: Similar to CAGL0G06226g Candida glabrata
IPF 3446.1; n=1; Yarrowia lipolytica|Rep: Similar to
CAGL0G06226g Candida glabrata IPF 3446.1 - Yarrowia
lipolytica (Candida lipolytica)
Length = 906
Score = 47.6 bits (108), Expect = 6e-04
Identities = 43/160 (26%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTF--APIHPPQSTSACKTSISLHHIDTKCTRNLEAYA 257
LA +T++E L+ V +E ++ + P QS ++ + + +D TR
Sbjct: 666 LAQHMTLIERDSLAEVDWKELIEARWNKKLEPVQSWTSYLVAKTNIGVDMVITR------ 719
Query: 258 DWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FN + V ++IL + R V+ +++ C + NF +LM I+ AL+ S V R
Sbjct: 720 --FNLVVNWVISEILLTKRLAERICVVSRFIHIAFLCREMQNFATLMQIVLALSSSHVSR 777
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFE 357
LK+TW + L +LE V P N L V+ +
Sbjct: 778 LKETWQHILPQDKKILAELEQIVVPLKNFHNLRQEFVSID 817
>UniRef50_A6SRC2 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 978
Score = 47.6 bits (108), Expect = 6e-04
Identities = 29/109 (26%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Query: 239 SISLHHIDT-KCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNL 297
S+SL+ + K N+ + FN ++ VA IL K+K+RA+++E+++ L
Sbjct: 773 SLSLNQKEKCKSLANVNRMINHFNHIAKWVANMILMRDKAKHRAQILEKFMNIALRLRQL 832
Query: 298 GNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
N+N L A+++ +N + + RL +T + A ++ +L L + +H
Sbjct: 833 NNYNGLAAVLAGINGTAIHRLTQTRNLVPADVQKRFARLVLLMGTQKSH 881
>UniRef50_O77086 Cluster: Guanine nucleotide-releasing factor 2; n=7;
melanogaster subgroup|Rep: Guanine nucleotide-releasing
factor 2 - Drosophila melanogaster (Fruit fly)
Length = 1571
Score = 47.6 bits (108), Expect = 6e-04
Identities = 20/68 (29%), Positives = 41/68 (60%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN++SY + IL+ +K R + + +++ + + N+NS +A++SAL+
Sbjct: 1377 NLNKFTEHFNKMSYWARSKILRLQDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALD 1436
Query: 312 MSPVMRLK 319
P+ RL+
Sbjct: 1437 SGPIRRLE 1444
>UniRef50_Q4S5W0 Cluster: Chromosome 9 SCAF14729, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF14729, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 980
Score = 47.2 bits (107), Expect = 8e-04
Identities = 26/82 (31%), Positives = 39/82 (47%)
Query: 243 HHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNS 302
H T NLE + FN + + VATD+ RA ++++++ N NS
Sbjct: 673 HKFPGAVTANLERFVRRFNEVQHWVATDLCLCTDLVKRALLLKKFIKIAAVLKEQKNLNS 732
Query: 303 LMAIISALNMSPVMRLKKTWSR 324
A++ L+ S V RL KTW R
Sbjct: 733 FFAVMFGLSNSAVRRLHKTWER 754
>UniRef50_Q7JTG3 Cluster: Nucleotide exchange factor RasGEF L; n=4;
Dictyostelium discoideum|Rep: Nucleotide exchange factor
RasGEF L - Dictyostelium discoideum (Slime mold)
Length = 2356
Score = 47.2 bits (107), Expect = 8e-04
Identities = 27/94 (28%), Positives = 50/94 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + FN++S V+T IL K K R ++I +++ + C +L N++ L A ++ +
Sbjct: 2152 NLLKMIERFNKISTGVSTAILSQPKIKTRVKLICRFIKIAQHCRDLNNYHLLTAFMAGIR 2211
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
S V+RL+ +W++ L LE + G+
Sbjct: 2212 NSNVVRLRLSWAKVPKKHLHILEDLEKIMSMEGS 2245
>UniRef50_Q2URQ9 Cluster: Ras1 guanine nucleotide exchange factor;
n=2; Aspergillus|Rep: Ras1 guanine nucleotide exchange
factor - Aspergillus oryzae
Length = 1652
Score = 47.2 bits (107), Expect = 8e-04
Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA QLTI+E+ LS + ++ V P S S + + R ++
Sbjct: 1410 LAQQLTIIEMAALSEIDWKDLVDMRWSSGSPSSVSWVQFLMEEER------RGIDLVVGR 1463
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + + ++I+ RAR I +++ T + N+ +++ I AL+ + RL+
Sbjct: 1464 FNLMVKWILSEIVLTRNIHERARTITKFIHTAAHARRMCNYATMLQIAIALSSTDCSRLQ 1523
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN 345
KTW + L+ +E+ ++P N
Sbjct: 1524 KTWGLVPSEDRGLLKDMEVLIQPVRN 1549
>UniRef50_Q4T188 Cluster: Chromosome undetermined SCAF10698, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10698, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1407
Score = 46.8 bits (106), Expect = 0.001
Identities = 60/246 (24%), Positives = 108/246 (43%), Gaps = 27/246 (10%)
Query: 107 IALVRVLRQWTSMFPYDF-RDDRVMA----LVRSITQRCAAEHMESVRVEMSTTLEKLLD 161
+ ++ V R W YDF RD ++ + SI + + +ES+ + + ++
Sbjct: 739 LRVLNVCRHWVEHHFYDFERDPNLLRTLEEFIASIRGKTMRKWVESITKIIQRKKQVQVN 798
Query: 162 KLTALEQYEESLVDIT-QVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEF 220
+ ++ S I + + Q D++TL P+E+A QLT++E V P E
Sbjct: 799 VPSHSITFQNSPPPIEWHICKPGNVEQFDLMTLH--PIEIARQLTLLESDFFRAVQPSEL 856
Query: 221 VQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYR 280
V + + S + H T NL WF + +V T+ L+ R
Sbjct: 857 VGSVWTKEDKELHSPNLLRMIRH------TTNLTL---WFEKC--IVETENLEE-----R 900
Query: 281 ARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCV 340
V+ + + + L NFN L+ ++SA+N SPV RL T+ + ++ +Q + LE
Sbjct: 901 VAVVSRIIEILQVFQELNNFNGLLEVVSAMNSSPVYRLDHTFEQLTS---RQRKILEEAH 957
Query: 341 EPTGNH 346
E + +H
Sbjct: 958 ELSEDH 963
>UniRef50_Q9N468 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 877
Score = 46.8 bits (106), Expect = 0.001
Identities = 27/77 (35%), Positives = 45/77 (58%), Gaps = 2/77 (2%)
Query: 248 KCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAII 307
K ++NL + + FN LS+ V T I+ K R R + ++V + + NFNS +AI+
Sbjct: 671 KKSKNLVNFTEQFNNLSFWVRTLIITQGTQKERERHMMKFVKIMKHLREMCNFNSYLAIL 730
Query: 308 SALNMSPVMRLKKTWSR 324
SA+ +P+ RL+ WS+
Sbjct: 731 SAIMSTPLARLE--WSK 745
>UniRef50_Q6CUP1 Cluster: Similar to ca|CA0382|IPF16030 Candida
albicans; n=1; Kluyveromyces lactis|Rep: Similar to
ca|CA0382|IPF16030 Candida albicans - Kluyveromyces
lactis (Yeast) (Candida sphaerica)
Length = 1360
Score = 46.8 bits (106), Expect = 0.001
Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 6/148 (4%)
Query: 202 NQLTIVELHRLSFVGPEEFVQT--FAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
N L I EL+ L +++ F I PP+ CK S + D + N+ +
Sbjct: 1064 NDLNISELNPLEVSKQISLIESTIFLKITPPELLK-CKYSSK--NPDLSKSPNVNSIITL 1120
Query: 260 FNRLS-YLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
N LS Y++ + ++ G+ K RA I+ W+ NFN+L +I++ L + RL
Sbjct: 1121 TNLLSNYVLESILMPGIPLKKRALRIKSWLRIALSSLYFRNFNALASIMTTLQSYVISRL 1180
Query: 319 KKTWSRTSAVCGQQLRQLELCVEPTGNH 346
W S + L + P N+
Sbjct: 1181 SMLWGMLSNEDVELFEYLSKIIHPNNNY 1208
>UniRef50_A3LVY6 Cluster: GDP/GTP exchange factor; n=2;
Saccharomycetaceae|Rep: GDP/GTP exchange factor - Pichia
stipitis (Yeast)
Length = 1235
Score = 46.8 bits (106), Expect = 0.001
Identities = 24/86 (27%), Positives = 43/86 (50%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + + ++I+ K R +I +++ ++C+ L NF++LM +I AL V +L+
Sbjct: 1028 FNLMVNWIISEIILTKNQKERISIISRFIHIAQKCYTLQNFSTLMQVILALTSEKVQQLR 1087
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN 345
TW + L+ LE P N
Sbjct: 1088 YTWKNLAPGDILMLKNLEELSSPLKN 1113
>UniRef50_Q54WL2 Cluster: RasGEF domain-containing protein; n=3;
Eukaryota|Rep: RasGEF domain-containing protein -
Dictyostelium discoideum AX4
Length = 1765
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N ++ FNR S V ++IL RA VIE+++ NL NF+ AI +
Sbjct: 1508 NFQSMVQLFNRWSSWVGSEILNCTTPASRALVIEKFIEIAFILLNLKNFHCCYAITQGIY 1567
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ RL TW + S Q +L+ NH
Sbjct: 1568 HYAIKRLYLTWDKISKKSMNQFEELQKIFSTESNH 1602
>UniRef50_UPI0000D55549 Cluster: PREDICTED: similar to CG3126-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3126-PA, isoform A - Tribolium castaneum
Length = 1063
Score = 46.0 bits (104), Expect = 0.002
Identities = 21/68 (30%), Positives = 38/68 (55%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN++SY T IL R + +++ + + NFNS +A++SAL+
Sbjct: 869 NLTRFTEHFNKMSYWARTRILTAEGKDVREKYFLKFIKIMKHLRKINNFNSYLALLSALD 928
Query: 312 MSPVMRLK 319
+P+ RL+
Sbjct: 929 SAPIRRLE 936
>UniRef50_A7EYT6 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 1095
Score = 46.0 bits (104), Expect = 0.002
Identities = 25/84 (29%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Query: 239 SISLHHIDT-KCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNL 297
S+SL+ + K N+ + FN ++ VA IL K+K+RA ++E+++ + L
Sbjct: 755 SLSLNQKEKCKSLANVNRMINHFNHIAKWVANMILMRDKAKHRAHILEKFMNIALKLRQL 814
Query: 298 GNFNSLMAIISALNMSPVMRLKKT 321
N+N L A+++ +N + + RL +T
Sbjct: 815 NNYNGLAAVLAGINGTAIHRLTQT 838
>UniRef50_Q5B8N8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized protein
- Emericella nidulans (Aspergillus nidulans)
Length = 1635
Score = 45.6 bits (103), Expect = 0.003
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA Q T+VE+ L V + V PP +TS + + R ++
Sbjct: 1392 LAEQFTLVEMAALGEVDWRDLVDMKWNSGPPFTTSWVQFLMDEER------RGIDLVVGR 1445
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + ++I+ + K RA I +++ T + N+ +++ I AL + RL+
Sbjct: 1446 FNLMVKWALSEIVLTLDIKERALTISKFIHTAVHARRMCNYATMLQICIALTSTDCSRLQ 1505
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN 345
TW+ + L+ LE+ ++P N
Sbjct: 1506 STWALVPLEDRRMLKDLEMLIQPVRN 1531
>UniRef50_UPI0001561679 Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial; n=3; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator, partial - Equus
caballus
Length = 849
Score = 45.2 bits (102), Expect = 0.003
Identities = 18/51 (35%), Positives = 31/51 (60%)
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSR 324
G+ ++ RARV+E W+ C ++ NF+S I+SA+ + LK+TW +
Sbjct: 364 GMTAQARARVVELWIQGAEGCRDVRNFSSFHTILSAVRSPAIKHLKETWGQ 414
>UniRef50_Q54XL4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 2050
Score = 45.2 bits (102), Expect = 0.003
Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H+ K N+ + FN +S V IL K K R +V+ +++ + L N+NSL
Sbjct: 1225 HLKDKAP-NIIKLINRFNEISMNVIQTILNEEKLKDRCKVMARFIKIAKNLHELHNYNSL 1283
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
MAI + ++ S + RLK T + L LE +E N
Sbjct: 1284 MAIYAGISHSSITRLKWTKKILPKTHQKTLSDLEKLMESDEN 1325
>UniRef50_Q5T7U6 Cluster: Ral guanine nucleotide dissociation
stimulator; n=29; Euteleostomi|Rep: Ral guanine
nucleotide dissociation stimulator - Homo sapiens
(Human)
Length = 309
Score = 45.2 bits (102), Expect = 0.003
Identities = 22/44 (50%), Positives = 28/44 (63%)
Query: 283 VIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
V EQ+ + EC L NF+SL AI+SAL + + RLKKTW S
Sbjct: 22 VAEQFTLMDAECRILKNFSSLYAILSALQSNSIHRLKKTWEDVS 65
>UniRef50_Q0TX72 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1654
Score = 45.2 bits (102), Expect = 0.003
Identities = 35/150 (23%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA Q T++E L + +E ++ + QS+ + + ++ T+ R ++
Sbjct: 1405 LAQQFTVIERDALDEIDWKELIE----LRWKQSSPQIRDWVQ--YLRTEEARGVDVVIAR 1458
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + V ++++ + RAR I +++ L N+ ++ I AL + V +L+
Sbjct: 1459 FNLVVKWVVSEVVLTENTHERARCIVKFIHIATHARRLRNYATMYQIAIALISNDVSKLR 1518
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW+ A +++LE V+P N L
Sbjct: 1519 KTWALVPAAELHVMKELEGIVQPLKNFHNL 1548
>UniRef50_UPI000049A05E Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 440
Score = 44.8 bits (101), Expect = 0.004
Identities = 21/75 (28%), Positives = 37/75 (49%)
Query: 247 TKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAI 306
T+ N+E Y W +++ VA I+ R + ++ +C + NFNS +I
Sbjct: 233 TRPNSNIELYYKWNQKITNWVAYSIINQKNEMIREMAFKNFLQLAIKCIEIKNFNSFNSI 292
Query: 307 ISALNMSPVMRLKKT 321
++ L V+R+KKT
Sbjct: 293 VNGLTHYAVIRMKKT 307
>UniRef50_A4D140 Cluster: Rap guanine nucleotide exchange factor
(GEF) 5; n=4; Eutheria|Rep: Rap guanine nucleotide
exchange factor (GEF) 5 - Homo sapiens (Human)
Length = 444
Score = 44.8 bits (101), Expect = 0.004
Identities = 22/80 (27%), Positives = 40/80 (50%)
Query: 267 VATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
+A +IL + R +++++++ C N NS AI+ LN + V RL +TW +
Sbjct: 264 IAQEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIP 323
Query: 327 AVCGQQLRQLELCVEPTGNH 346
+ +LE +P+ NH
Sbjct: 324 GKFKKLFSELESLTDPSLNH 343
>UniRef50_Q8X027 Cluster: Related to aimless RasGEF; n=2; Neurospora
crassa|Rep: Related to aimless RasGEF - Neurospora
crassa
Length = 985
Score = 44.8 bits (101), Expect = 0.004
Identities = 24/96 (25%), Positives = 51/96 (53%)
Query: 251 RNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+N+ FN ++ V+ IL K+K+RA +E++++ + L N+N L A+++ +
Sbjct: 771 KNVNRMVSHFNHIAQWVSNMILIRDKAKHRAPCLERFMVIAQRLRTLNNYNGLAAVLAGI 830
Query: 311 NMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
N + + RL +T + S ++ +L L + +H
Sbjct: 831 NGTAIHRLAQTRNLVSPDVQKRFARLVLLMGTQKSH 866
>UniRef50_Q2GV74 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 1803
Score = 44.8 bits (101), Expect = 0.004
Identities = 38/146 (26%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA Q T+VE L+ + +E ++ + Q ++ +S DT R +E
Sbjct: 1554 LAQQFTLVEKDALNEIDWKELIEMRWK-NAEQKGIHVRSWVSFLR-DTDA-RGVEVVIAR 1610
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + ++I+ + RAR I +++ C NF ++ + AL + V RL
Sbjct: 1611 FNIMVKWAISEIVLTQDMEERARCIIKFIHIAAHCRRYRNFATMSQVTIALTSNEVSRLN 1670
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN 345
TW+ A + L +LE + PT N
Sbjct: 1671 NTWAMVPAGDKRTLTELEALLSPTRN 1696
>UniRef50_Q54GB4 Cluster: Ras guanine nucleotide exchange factor;
n=2; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor - Dictyostelium discoideum
AX4
Length = 944
Score = 44.4 bits (100), Expect = 0.006
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 238 TSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNL 297
T + L H T +E F+ +S V+T I++G K R +++ +++ NL
Sbjct: 753 TCVDLKHKTPHITNIMER----FHNISTWVSTTIVRGENLKNRVKIVNKFIKIAEHLKNL 808
Query: 298 GNFNSLMAIISALNMSPVMR 317
NFNSL AI+ A+ S V +
Sbjct: 809 NNFNSLTAILVAIQRSTVTK 828
>UniRef50_A2QDU9 Cluster: Contig An02c0260, complete genome; n=4;
Trichocomaceae|Rep: Contig An02c0260, complete genome -
Aspergillus niger
Length = 1699
Score = 44.4 bits (100), Expect = 0.006
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA QLT+VE+ LS V + V P S + + H R ++
Sbjct: 1457 LAQQLTLVEMAALSEVDWRDLVDMRWSSGSPTMLSWVQFLMEEEH------RGIDLVVGR 1510
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + V ++I+ RAR I +++ T + N+ +++ I AL+ + RL+
Sbjct: 1511 FNLMVRWVLSEIVLTQDIHERARTIAKFIHTAAHARRMCNYATMLQIAIALSSTDCSRLQ 1570
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
TW + L+ +E +P N L
Sbjct: 1571 ATWDLVPVADKRLLKDMESLTQPIRNFHEL 1600
>UniRef50_Q59Z59 Cluster: Putative uncharacterized protein LTE1;
n=1; Candida albicans|Rep: Putative uncharacterized
protein LTE1 - Candida albicans (Yeast)
Length = 715
Score = 44.0 bits (99), Expect = 0.008
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + + ++IL R +I +++ + C L NF +LM II AL + +LK
Sbjct: 510 FNLMVNWIISEILLTQSPNERIHLISRFIHIAQHCLELQNFATLMQIILALTSQRIQKLK 569
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN--HARLSGNRVNFEK 358
+TW L+ LE P N + RL+ N++ K
Sbjct: 570 QTWKDLIPGDILLLKNLEELASPLKNFLNIRLTINQIKPSK 610
>UniRef50_A5DL36 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1287
Score = 44.0 bits (99), Expect = 0.008
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + V ++IL R +I +++ + C+ + N+ S+M I+ AL + LK
Sbjct: 1097 FNLMVNWVISEILLTKAQSERIHLISRFIHIAQHCYAMQNYASMMQILLALTSEKIGHLK 1156
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN--HARLSGNRVNFEK 358
+TW L+ LE P N + RLS N++ K
Sbjct: 1157 ETWKNLLPGDILSLKNLEELTSPVKNFLNIRLSINQIKPSK 1197
>UniRef50_Q9UHV5 Cluster: Rap guanine nucleotide exchange
factor-like protein 1; n=15; Euteleostomi|Rep: Rap
guanine nucleotide exchange factor-like protein 1 - Homo
sapiens (Human)
Length = 456
Score = 43.2 bits (97), Expect = 0.014
Identities = 24/97 (24%), Positives = 46/97 (47%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NLE + +++ VAT++L RA+++++++ C + S A++
Sbjct: 256 TANLELLLQRCSEVTHWVATEVLLCEAPGKRAQLLKKFIKIAALCKQNQDLLSFYAVVMG 315
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
L+ + V RL+ TW + R+ E +P NH
Sbjct: 316 LDNAAVSRLRLTWEKLPGKFKNLFRKFENLTDPCRNH 352
>UniRef50_A7F2T0 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 1721
Score = 43.2 bits (97), Expect = 0.014
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 9/160 (5%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA Q T++E L+ + ++ ++ +A T + + + R +E
Sbjct: 1477 LAQQFTLIEKDALNEIDWKDLIEM------RWRDAATDTRSWVEFLRSSEPRGVEVVIAR 1530
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + ++I+ + R R I +++ C NF ++ + AL + RL
Sbjct: 1531 FNIMVKWAVSEIVLTGDLEERVRCIIKYIHIAVNCRKYRNFATMTQLTVALTSKDISRLT 1590
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEKC 359
TW+ A Q L +LE V PT N L R E C
Sbjct: 1591 STWAHVPASDIQTLHELEELVTPTSNFHNL---RAEMEGC 1627
>UniRef50_A4R2V9 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1741
Score = 43.2 bits (97), Expect = 0.014
Identities = 28/99 (28%), Positives = 45/99 (45%)
Query: 251 RNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
R +E FN + ++I+ + RAR + +++ C NF ++ I AL
Sbjct: 1540 RGVEVVIARFNIMVKWCVSEIVLTQDLEERARCLIKFIHIAAHCRRYRNFATMSQIAIAL 1599
Query: 311 NMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
V +L++TW+ A L+QLE V PT N L
Sbjct: 1600 TSPEVSKLQRTWAMVPASDLTTLQQLEALVSPTRNFYNL 1638
>UniRef50_P26675 Cluster: Protein son of sevenless; n=6;
Endopterygota|Rep: Protein son of sevenless - Drosophila
melanogaster (Fruit fly)
Length = 1596
Score = 43.2 bits (97), Expect = 0.014
Identities = 55/245 (22%), Positives = 102/245 (41%), Gaps = 27/245 (11%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
++ VLR W YDF D + L+ + + +S+R + + L K++ + E+
Sbjct: 740 VLNVLRHWVDHHFYDFEKDPM--LLEKLLNFLEHVNGKSMRKWVDSVL-KIVQRKNEQEK 796
Query: 169 YEESLV-----DITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQT 223
+ +V D + + +I L L P+ELA QLT++E V P E V +
Sbjct: 797 SNKKIVYAYGHDPPPIEHHLSVPNDEITLLTLHPLELARQLTLLEFEMYKNVKPSELVGS 856
Query: 224 FAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARV 283
+ S I H T TR W + I + + R +
Sbjct: 857 PWTKKDKEVKSPNLLKIMKH--TTNVTR-------WIEK-------SITEAENYEERLAI 900
Query: 284 IEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPT 343
+++ + L NFN +++I++A+ + V RL+ T+ + + + LE C E +
Sbjct: 901 MQRAIEVMMVMLELNNFNGILSIVAAMGTASVYRLRWTF---QGLPERYRKFLEECRELS 957
Query: 344 GNHAR 348
+H +
Sbjct: 958 DDHLK 962
>UniRef50_Q07889 Cluster: Son of sevenless homolog 1; n=70; cellular
organisms|Rep: Son of sevenless homolog 1 - Homo sapiens
(Human)
Length = 1333
Score = 43.2 bits (97), Expect = 0.014
Identities = 66/278 (23%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 78 TEKSDIEYRDG-QIGKAEVKDLVEKELNDM-IALVRVLRQWTSMFPYDFRDD-----RVM 130
TE I +G Q AE+K ++ + + + ++ V R W YDF D R+
Sbjct: 656 TEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRME 715
Query: 131 ALVRSITQRCAAEHMESVR--VEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQG 188
+ ++ + + +ES+ ++ Q V+ +S +
Sbjct: 716 EFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVE-WHISRPGHIETF 774
Query: 189 DILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTK 248
D+LTL P+E+A QLT++E V P E V + + S + H
Sbjct: 775 DLLTLH--PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRH----- 827
Query: 249 CTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIIS 308
T NL WF + +V T+ L+ R V+ + + + L NFN ++ ++S
Sbjct: 828 -TTNLTL---WFEKC--IVETENLEE-----RVAVVSRIIEILQVFQELNNFNGVLEVVS 876
Query: 309 ALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A+N SPV RL T+ + + +Q + LE E + +H
Sbjct: 877 AMNSSPVYRLDHTFEQ---IPSRQKKILEEAHELSEDH 911
>UniRef50_UPI00015B5730 Cluster: PREDICTED: similar to
guanine-nucleotide exchange factor c3g; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to guanine-nucleotide
exchange factor c3g - Nasonia vitripennis
Length = 1238
Score = 42.7 bits (96), Expect = 0.018
Identities = 21/71 (29%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Query: 252 NLEAYADWFNRLSYLVATDILKGV---KSKYRARVIEQWVMTGRECFNLGNFNSLMAIIS 308
NL + + FN++SY + IL+ ++K R + + +++ + + NFNS +A++S
Sbjct: 1039 NLTRFTEHFNKMSYWARSRILEHRMENEAKDREKYVVKFIKIMKHLRKINNFNSYLALLS 1098
Query: 309 ALNMSPVMRLK 319
AL+ +P+ RL+
Sbjct: 1099 ALDSAPIRRLE 1109
>UniRef50_UPI0000519C35 Cluster: PREDICTED: similar to C3G CG3126-PA,
isoform A; n=2; Apis mellifera|Rep: PREDICTED: similar to
C3G CG3126-PA, isoform A - Apis mellifera
Length = 1176
Score = 42.7 bits (96), Expect = 0.018
Identities = 21/71 (29%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Query: 252 NLEAYADWFNRLSYLVATDILKGV---KSKYRARVIEQWVMTGRECFNLGNFNSLMAIIS 308
NL + + FN++SY + IL+ ++K R + + +++ + + NFNS +A++S
Sbjct: 977 NLTRFTEHFNKMSYWARSRILEHRLENEAKDREKYVVKFIKIMKHLRKINNFNSYLALLS 1036
Query: 309 ALNMSPVMRLK 319
AL+ +P+ RL+
Sbjct: 1037 ALDSAPIRRLE 1047
>UniRef50_UPI0000498500 Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 1208
Score = 42.7 bits (96), Expect = 0.018
Identities = 25/86 (29%), Positives = 42/86 (48%)
Query: 251 RNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+N+ +FN L IL ++ RA +IE+ V CF NF++L+ I+
Sbjct: 292 QNIVYAQTFFNGLQNHFTRMILNETETTQRAAIIERLVRVADYCFEYHNFDTLLCILLLF 351
Query: 311 NMSPVMRLKKTWSRTSAVCGQQLRQL 336
N S + RLK+++ S + L +L
Sbjct: 352 NTSSIHRLKRSFDSISGESKKILNKL 377
>UniRef50_Q4S7S0 Cluster: Chromosome 18 SCAF14712, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18
SCAF14712, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 782
Score = 42.7 bits (96), Expect = 0.018
Identities = 20/34 (58%), Positives = 24/34 (70%)
Query: 293 ECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
EC L NF+SL AI+SAL + V RLKKTW+ S
Sbjct: 295 ECRQLKNFSSLRAILSALQSNAVYRLKKTWAAVS 328
>UniRef50_Q54FF3 Cluster: Ras guanine nucleotide exchange factor; n=4;
Eukaryota|Rep: Ras guanine nucleotide exchange factor -
Dictyostelium discoideum AX4
Length = 1557
Score = 42.7 bits (96), Expect = 0.018
Identities = 22/62 (35%), Positives = 38/62 (61%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S V + IL+ + K RA+ +++ + E L N+N+ +A+IS +N S ++RLK
Sbjct: 1365 FNDISLWVVSLILEPDRVKTRAKRLKRIISIADELRKLNNYNTCIAVISGINNSAILRLK 1424
Query: 320 KT 321
T
Sbjct: 1425 YT 1426
>UniRef50_A5E0J4 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1660
Score = 42.3 bits (95), Expect = 0.024
Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 16/135 (11%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFV-QTFAPIHPPQSTSACKTSISLHHIDTKCTR 251
L +E+A QLTI+E + + PEE + Q F S ++ L + T C
Sbjct: 1378 LDFNGLEIAKQLTIIESTIFTAIQPEELLNQNFTNKRAHLKLSP---NVRLSLLFTNCLS 1434
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N Y++ + + + K R ++ W+ L NFNSL AII+AL
Sbjct: 1435 N------------YVLESVLQPNLSDKERVNTVKVWLKIAISSLYLRNFNSLAAIIAALQ 1482
Query: 312 MSPVMRLKKTWSRTS 326
+ R+ W+ S
Sbjct: 1483 SHLITRVDFLWANLS 1497
>UniRef50_UPI000049A5AB Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 602
Score = 41.9 bits (94), Expect = 0.032
Identities = 47/229 (20%), Positives = 97/229 (42%), Gaps = 29/229 (12%)
Query: 95 VKDLVEKELNDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMST 154
+++++ ++ALV++L Q +FP DF++++ + + Q + M
Sbjct: 246 IQNIIIPTRTRILALVKMLIQ---VFPNDFKEEQNQEAINDLIQLYTTYNKS-----MGL 297
Query: 155 TLEKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSF 214
L+K D L+ L + +D G L ++P++ A Q+T++++
Sbjct: 298 NLQKSFDNRFGLKMECVILKRNVPLLPVDDKFSG---ILCISPLDFAEQMTLIQMESFVE 354
Query: 215 VGPEEFV-QTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILK 273
+ +EF+ Q + + Q T I L N+L ++V T+I+
Sbjct: 355 IPSDEFLNQGWTKKNKEQLTPHIVNMIKLS-----------------NKLIHIVQTEIVM 397
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTW 322
R+ + ++ + NF+ + AI++AL V RLK +W
Sbjct: 398 QPTYALRSLALFYFITAAETMRTIQNFDGMKAIVTALQSVSVFRLKVSW 446
>UniRef50_A6RN08 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 370
Score = 41.9 bits (94), Expect = 0.032
Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 6/150 (4%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA Q T++E L+ + ++ ++ +A T + + + R +E
Sbjct: 126 LAQQFTLIEKDALNEIDWKDLIEM------RWRDAATDTRSWVDFLRSSEPRGVEVVIAR 179
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + ++I+ + R R I +++ C NF ++ + AL + RL
Sbjct: 180 FNIMVKWAVSEIVLTGDLEERVRCIIKYIHIAVNCRKYRNFATMTQLTVALTSKDISRLT 239
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
TW+ A Q L +LE V PT N L
Sbjct: 240 STWAHVPASDIQTLNELEELVTPTSNFHNL 269
>UniRef50_A5DX26 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1635
Score = 41.5 bits (93), Expect = 0.042
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 2/101 (1%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + + ++I+ R +I +++ + C L NF +LM II AL + L+
Sbjct: 1411 FNLMVNWIISEIILTQSQTERINIISRFIHIAQNCLILQNFTTLMQIILALTSQRIQNLR 1470
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN--HARLSGNRVNFEK 358
TW L+ LE P N + RL N++ K
Sbjct: 1471 NTWRNLPPGDILMLKTLEELASPLKNFINIRLCINQITPSK 1511
>UniRef50_A5DA53 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1791
Score = 41.5 bits (93), Expect = 0.042
Identities = 19/47 (40%), Positives = 28/47 (59%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
+AR+IE+W+ G LGN +S + I S + P++RL K WS S
Sbjct: 466 KARLIEKWIDLGCLLDKLGNMSSWLGISSIILSQPILRLTKIWSLVS 512
>UniRef50_UPI000156177D Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator; n=3; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator - Equus caballus
Length = 685
Score = 41.1 bits (92), Expect = 0.055
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
G+ ++ RARV E W+ + L NF+S I+SAL + + RLK TW + S
Sbjct: 400 GMTAQERARVEELWIHAAKLSI-LKNFSSFHMILSALQIPAIKRLKDTWGQVS 451
>UniRef50_UPI000065E6FA Cluster:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase epsilon 1 (EC 3.1.4.11) (Phospholipase
C-epsilon-1) (PLC-epsilon-1) (Phosphoinositide-specific
phospholipase C epsilon-1) (Pancreas- enriched
phospholipase C).; n=9; Euteleostomi|Rep:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase epsilon 1 (EC 3.1.4.11) (Phospholipase
C-epsilon-1) (PLC-epsilon-1) (Phosphoinositide-specific
phospholipase C epsilon-1) (Pancreas- enriched
phospholipase C). - Takifugu rubripes
Length = 1761
Score = 41.1 bits (92), Expect = 0.055
Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 2/128 (1%)
Query: 237 KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGREC 294
K S+S+ + T+ +R+ +E FN +S V IL + + V V + C
Sbjct: 126 KASLSVPAMSTQSSRHNAVEDLVARFNEVSSWVTWLILTAGSMEEKREVFSYLVNVAKCC 185
Query: 295 FNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRV 354
+N+GN+N +M ++ L V+++ + +T + L+ E + + ++ +
Sbjct: 186 WNMGNYNGVMEFLAGLRSRKVLKMWQFMDQTDIETMRSLKDAMAQHESSSEYKKVVTRAL 245
Query: 355 NFEKCALL 362
N C ++
Sbjct: 246 NIPGCKVV 253
>UniRef50_Q873I0 Cluster: Related to LTE1 protein; n=2; Neurospora
crassa|Rep: Related to LTE1 protein - Neurospora crassa
Length = 1792
Score = 41.1 bits (92), Expect = 0.055
Identities = 41/175 (23%), Positives = 73/175 (41%), Gaps = 4/175 (2%)
Query: 175 DITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTS 234
D+T+ S +LS L LA Q T++E L+ + E + + Q
Sbjct: 1519 DVTEASD-SRLSAHLPFILAFDSEILAQQFTLIEKDALNEIDWRELIDMRWK-NAEQKGC 1576
Query: 235 ACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGREC 294
++ +S DT +E FN + ++I+ + RAR I + + C
Sbjct: 1577 DARSWVSFLR-DTDA-HGVEVVIARFNIMVKWAISEIVLTRDIEERARCIIKLIHIAAHC 1634
Query: 295 FNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
NF ++ + AL + + RL KTW+ + + +++LE + PT N L
Sbjct: 1635 RRFRNFATMAQLTIALMSNEIGRLNKTWAMVPSSDQRTMQELETLMSPTRNFYNL 1689
>UniRef50_Q6FT12 Cluster: Guanine nucleotide exchange factor LTE1;
n=1; Candida glabrata|Rep: Guanine nucleotide exchange
factor LTE1 - Candida glabrata (Yeast) (Torulopsis
glabrata)
Length = 1318
Score = 41.1 bits (92), Expect = 0.055
Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 11/127 (8%)
Query: 199 ELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHH---IDTKCTRNLEA 255
++A Q T++E LS + ++ + P TS + I ID R
Sbjct: 1076 DVAQQFTLIEREILSEIDWKDLLDIKLLYKGPNLTSWLQLLIQNQEFTGIDLAVAR-FNL 1134
Query: 256 YADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPV 315
DW +S +V T LK R IE+++ C L NFN++M II ALN V
Sbjct: 1135 TVDW--AISEIVLTTDLK-----MRRNTIERFIHVAEHCRKLQNFNTMMQIILALNSVVV 1187
Query: 316 MRLKKTW 322
+ + W
Sbjct: 1188 QKFTEAW 1194
>UniRef50_Q4RG56 Cluster: Chromosome 2 SCAF15106, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF15106, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1617
Score = 40.7 bits (91), Expect = 0.073
Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 7/173 (4%)
Query: 197 PVELANQLTIVELHRLSFVGPEEFVQTFAP-IHPPQSTS----ACKTSISLHHIDTKCTR 251
P E+A LT E V P ++++ + P+ S + K S+S+ + T+ +R
Sbjct: 35 PEEIACILTEQEQQLYQQVFPLDYLRFLTKDLGSPECQSKHHPSLKASLSVPAMSTQSSR 94
Query: 252 N--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
+ +E FN +S V IL + + V V + C+N+GN+N +M ++
Sbjct: 95 HNAVEDLVARFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNGVMEFLAG 154
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEKCALL 362
L V+++ + +T + L+ E + + ++ N C ++
Sbjct: 155 LRSRKVLKMWQFMDQTDIETMRSLKDAMAQHESSSEYKKIVTRARNIPGCKVV 207
>UniRef50_A7SA05 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 434
Score = 40.7 bits (91), Expect = 0.073
Identities = 22/67 (32%), Positives = 37/67 (55%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN++SY + IL K + R + +++ + NFNS +AI+SA++
Sbjct: 245 NLTVFTENFNKVSYWSRSYILSFEKPQDREKAYLKFLKIMKHLRRFNNFNSFLAILSAMD 304
Query: 312 MSPVMRL 318
S V RL
Sbjct: 305 CSAVRRL 311
>UniRef50_A2F534 Cluster: RasGEF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: RasGEF domain containing
protein - Trichomonas vaginalis G3
Length = 853
Score = 40.7 bits (91), Expect = 0.073
Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 2/95 (2%)
Query: 236 CKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKS--KYRARVIEQWVMTGRE 293
C+ ++ K +L FN LS + I+ K K A +I QW++ +
Sbjct: 630 CREYVNCSWTKNKHAPHLIEITTNFNHLSQYIQYTIVNFTKKDPKATAFIIAQWILIMEK 689
Query: 294 CFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAV 328
C + NF L I SAL+ V L K W + +
Sbjct: 690 CRIINNFQGLFVIESALSSPSVAGLHKCWDALNEI 724
>UniRef50_Q8TDF6 Cluster: RAS guanyl-releasing protein 4; n=32;
Theria|Rep: RAS guanyl-releasing protein 4 - Homo
sapiens (Human)
Length = 673
Score = 40.7 bits (91), Expect = 0.073
Identities = 27/96 (28%), Positives = 45/96 (46%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
LE N +S V +L RA+V+++++ + L NFN+LMA+ L
Sbjct: 240 LEGSVGLSNSVSRWVQVMVLSRPGPLQRAQVLDKFIHVAQRLHQLQNFNTLMAVTGGLCH 299
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
S + RLK + + S + L +L + N+AR
Sbjct: 300 SAISRLKDSHAHLSPDSTKALLELTELLASHNNYAR 335
>UniRef50_Q8N437 Cluster: RASGEF1B protein; n=8; Euteleostomi|Rep:
RASGEF1B protein - Homo sapiens (Human)
Length = 210
Score = 40.7 bits (91), Expect = 0.073
Identities = 14/34 (41%), Positives = 25/34 (73%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAA 142
++++L +WT FPYDFRD+R+M ++ + R A+
Sbjct: 110 ILQLLTEWTETFPYDFRDERMMRNLKDLAHRIAS 143
>UniRef50_Q6UNM9 Cluster: LTE1-like protein; n=1; Epichloe
festucae|Rep: LTE1-like protein - Epichloe festucae
Length = 1672
Score = 40.7 bits (91), Expect = 0.073
Identities = 26/86 (30%), Positives = 40/86 (46%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + ++I+ + + RAR I + + C NF +L + AL+ + V RL
Sbjct: 1484 FNIMVKWAISEIVLTQQVEERARCIIKLIHIAAHCRRYRNFATLAQLTIALSSNEVSRLS 1543
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGN 345
KTW Q L LE+ V P+ N
Sbjct: 1544 KTWELVPERDLQTLHDLEILVTPSRN 1569
>UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange
factor 3 (cAMP-regulated guanine nucleotide exchange
factor I) (cAMP-GEFI) (Exchange factor directly
activated by cAMP 1) (Epac 1) (Rap1
guanine-nucleotide-exchange factor directly activated by
cAMP).; n=1; Takifugu rubripes|Rep: Rap guanine
nucleotide exchange factor 3 (cAMP-regulated guanine
nucleotide exchange factor I) (cAMP-GEFI) (Exchange
factor directly activated by cAMP 1) (Epac 1) (Rap1
guanine-nucleotide-exchange factor directly activated by
cAMP). - Takifugu rubripes
Length = 908
Score = 40.3 bits (90), Expect = 0.096
Identities = 23/80 (28%), Positives = 37/80 (46%)
Query: 243 HHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNS 302
H T NLE + FN + + V T++ RA ++++++ N NS
Sbjct: 682 HKFPGATTANLERFVRRFNEVQHWVVTELCLCEDLVKRAVLLKKFIKIASVLKEQKNLNS 741
Query: 303 LMAIISALNMSPVMRLKKTW 322
A++ L+ S V RL KTW
Sbjct: 742 FFAVMFGLSNSAVRRLYKTW 761
>UniRef50_A2RRV5 Cluster: Histone H2A; n=2; Danio rerio|Rep: Histone
H2A - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 713
Score = 39.9 bits (89), Expect = 0.13
Identities = 48/181 (26%), Positives = 79/181 (43%), Gaps = 24/181 (13%)
Query: 166 LEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFA 225
+ YE S DIT D+ +L L P+E+A QLT++E V P E V +
Sbjct: 152 IRHYEISQQDITVAMCADK-----VLMDMLHPIEIARQLTLLESDFYRAVQPSELVGSVW 206
Query: 226 PIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIE 285
+ S + H T NL W + +V T+ ++ R V+
Sbjct: 207 TKEDKEINSPNLLRMIRH------TTNLTL---WLEKC--IVETENVEE-----RVSVVS 250
Query: 286 QWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
+ + + L NFN ++ ++SA+N SPV RL T+ + + +Q + LE E + +
Sbjct: 251 RIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQ---IPSRQRKILEEAHELSED 307
Query: 346 H 346
H
Sbjct: 308 H 308
>UniRef50_Q550U8 Cluster: Ras guanine nucleotide exchange factor;
n=2; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor - Dictyostelium discoideum
AX4
Length = 604
Score = 39.9 bits (89), Expect = 0.13
Identities = 46/207 (22%), Positives = 80/207 (38%), Gaps = 23/207 (11%)
Query: 113 LRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEES 172
+R W P DF + + L I + AA H + +R ++ +E + ++ E
Sbjct: 289 IRFWIEQHPTDFNEKLLAILNNFIEHQVAASHAKQLRAVINLKIENYKEARKEIKDPPEP 348
Query: 173 LVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQS 232
V S L+ DI E+A QL ++ + P EF+ PQ
Sbjct: 349 KVPKNIFSPT--LTFDDI-----DEEEIARQLCCIDFALYELIKPSEFL--IKGWTKPQY 399
Query: 233 TSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGR 292
+ +++ R + W +A IL SK R++++ +++
Sbjct: 400 RNKAVNLLNM-------MRRFNDFTKW-------IAASILNEQNSKGRSKLLGRFLKISE 445
Query: 293 ECFNLGNFNSLMAIISALNMSPVMRLK 319
NF+SLMAI +N + V R K
Sbjct: 446 HLRANNNFHSLMAIYGGINNTHVFRTK 472
>UniRef50_Q9HF75 Cluster: GTPase-activating protein BEM2; n=1;
Eremothecium gossypii|Rep: GTPase-activating protein
BEM2 - Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 2071
Score = 39.9 bits (89), Expect = 0.13
Identities = 19/49 (38%), Positives = 28/49 (57%)
Query: 274 GVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTW 322
G K RA V+ +WV G + LG+ S +AI + + PV+RL +TW
Sbjct: 539 GFTPKKRAEVLTKWVQLGCKFERLGDMVSWLAIATVICSIPVLRLTRTW 587
>UniRef50_UPI0000499791 Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 598
Score = 39.5 bits (88), Expect = 0.17
Identities = 23/98 (23%), Positives = 44/98 (44%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + N + +V IL+ ++ RA I ++ L NF+ + A+++ L
Sbjct: 371 NLLKMVRFSNNIINVVQKKILELEQNYERAFAIRYFISVAHYLKQLNNFDGMKAVLAGLE 430
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+ RLK++W S +QL+ + P N ++
Sbjct: 431 SCSIYRLKESWGLLSIDEINLFKQLDSLISPDNNFCKM 468
>UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5;
Euteleostomi|Rep: Sh2d3c-prov protein - Xenopus laevis
(African clawed frog)
Length = 676
Score = 39.5 bits (88), Expect = 0.17
Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A+++AL MS + R
Sbjct: 456 FHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKGTMGNMFSFAAVMNALEMSQISR 515
Query: 318 LKKTW 322
L++TW
Sbjct: 516 LEQTW 520
>UniRef50_Q4PFF2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 2649
Score = 39.5 bits (88), Expect = 0.17
Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 10/142 (7%)
Query: 185 LSQGDILTLGLTPVELANQLTIVELHRLS-FVGPE-EFVQTF--APIHPPQSTSACKTSI 240
L+ D L L L P+E+A Q+ + L V P+ F Q + H ++ S+
Sbjct: 869 LTISDELLLELEPLEIAQQIQLFHADALRRLVSPQLSFCQLLEASKAHNQFVSALSFDSL 928
Query: 241 SLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNF 300
S H + T ++L N S +++RA V+ W+ +G+
Sbjct: 929 SPHPLTTLALKHL------LNTSSIKTDGPSAAQTGARHRASVLRHWIAIASYLLTMGDV 982
Query: 301 NSLMAIISALNMSPVMRLKKTW 322
MA+ +AL V RL++TW
Sbjct: 983 AGWMAVSTALCSRAVTRLEQTW 1004
>UniRef50_A5E683 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 2219
Score = 39.5 bits (88), Expect = 0.17
Identities = 18/47 (38%), Positives = 27/47 (57%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
+AR++E+W+ G GN +S + I S + PV+RL K WS S
Sbjct: 729 KARILEKWIDLGCLLDKSGNMSSWLGISSIILSQPVLRLTKIWSLVS 775
>UniRef50_UPI00015B5A66 Cluster: PREDICTED: similar to phospholipase
c epsilon; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to phospholipase c epsilon - Nasonia vitripennis
Length = 1801
Score = 39.1 bits (87), Expect = 0.22
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 251 RNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
++++ D FN ++ V+ I G + R ++ + + C+N+GNFNS M I++ L
Sbjct: 107 QHVQTLIDRFNEVNSWVSHVISSGSTVEERQALLSCLLRVAQTCWNIGNFNSAMEIVAGL 166
Query: 311 NMSPVMRLKKTWSRTS 326
+ +LK W S
Sbjct: 167 KSN---KLKPFWQTVS 179
>UniRef50_Q5RH52 Cluster: Novel RasGEF domain containing protein;
n=6; Euteleostomi|Rep: Novel RasGEF domain containing
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 564
Score = 39.1 bits (87), Expect = 0.22
Identities = 17/54 (31%), Positives = 31/54 (57%)
Query: 296 NLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
++ + +++MA++SAL +P+ RL KTW+ S +LE + N+ RL
Sbjct: 111 DMNSLHAVMAVVSALQSAPIFRLTKTWALLSRKDKATFERLEYLMSKEDNYKRL 164
>UniRef50_Q4T1D4 Cluster: Chromosome undetermined SCAF10661, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10661, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 564
Score = 39.1 bits (87), Expect = 0.22
Identities = 18/62 (29%), Positives = 32/62 (51%)
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHA 347
V+ ++ L N ++L++++SAL +P+ RL KTWS S +L N+
Sbjct: 132 VVCWQKLLELNNLHALVSVLSALQSAPIFRLSKTWSLISRKDKATFEKLNYLTSKEENYT 191
Query: 348 RL 349
R+
Sbjct: 192 RM 193
>UniRef50_Q9GQC2 Cluster: Ras guanine nucleotide exchange factor
RasGEFB; n=3; Dictyostelium discoideum|Rep: Ras guanine
nucleotide exchange factor RasGEFB - Dictyostelium
discoideum (Slime mold)
Length = 1529
Score = 39.1 bits (87), Expect = 0.22
Identities = 25/77 (32%), Positives = 39/77 (50%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T N+ + + FN S V+ IL+ K R++++ + + + L NFN L+A +S
Sbjct: 1320 TPNIASMVNRFNSFSSFVSWAILRENDIKQRSKMMLKMIKICYALYKLSNFNGLLAGLSG 1379
Query: 310 LNMSPVMRLKKTWSRTS 326
L S V RL T S S
Sbjct: 1380 LMASGVYRLNHTKSLIS 1396
>UniRef50_UPI0000498D55 Cluster: Ras guanine nucleotide exchange
factor; n=2; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 830
Score = 38.7 bits (86), Expect = 0.29
Identities = 19/77 (24%), Positives = 38/77 (49%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + A IL R ++++ + C+ L N+N ++ I+S + S + RL
Sbjct: 259 FNAIQNFFAIQILNKKNIFKRCKILQHIIDIAYYCYTLQNYNIVVCIVSLFSTSAIHRLH 318
Query: 320 KTWSRTSAVCGQQLRQL 336
KT++ S++ + +L
Sbjct: 319 KTFNNISSLHKNKFNEL 335
>UniRef50_Q54L90 Cluster: RasGEF domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: RasGEF
domain-containing protein - Dictyostelium discoideum AX4
Length = 1601
Score = 38.7 bits (86), Expect = 0.29
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 17/182 (9%)
Query: 156 LEKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFV 215
L K + T + ++L+ + S G + L+ +E+A Q T+V+ + V
Sbjct: 981 LPKRVHSRTRSASFSDTLLSTGGIGSTSGGIGGGVNNCLLSAMEIAEQCTLVDYDLFTNV 1040
Query: 216 GPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGV 275
++V+ PQ+ S+SL + +A W +IL
Sbjct: 1041 RLSDWVRLVQGSVDPQTAP----SLSL------ALKRSTIWAQW-------AMGEILSTE 1083
Query: 276 KSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQ 335
R +I V C +L NFN+ ++I +AL + RL++TW ++ Q
Sbjct: 1084 DKSQRVAIINLLVDVAINCKDLANFNTAISIHTALTNHHIKRLQQTWDSVPKETLNKITQ 1143
Query: 336 LE 337
LE
Sbjct: 1144 LE 1145
>UniRef50_A2DUN7 Cluster: RasGEF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: RasGEF domain containing
protein - Trichomonas vaginalis G3
Length = 704
Score = 38.7 bits (86), Expect = 0.29
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Query: 236 CKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECF 295
C+ L D C R + + N Y + IL SK RAR I W+ T
Sbjct: 495 CEIVSKLSVDDILCQRFHDIVRSFNNTCDY-ICRHILTD-DSKNRARNISYWIDTMTYSA 552
Query: 296 NLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
LGN + I +ALN + RL+++W S
Sbjct: 553 QLGNLFLVFEISAALNSPAISRLRRSWDLVS 583
>UniRef50_A3LSD7 Cluster: Bud-emergence protein; n=2;
Saccharomycetaceae|Rep: Bud-emergence protein - Pichia
stipitis (Yeast)
Length = 1747
Score = 38.7 bits (86), Expect = 0.29
Identities = 18/47 (38%), Positives = 27/47 (57%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
+AR++E+W+ G GN +S + I S + PV+RL K WS S
Sbjct: 386 KARLLEKWIDLGCLLDKSGNMSSWLGISSIILSQPVLRLTKIWSLVS 432
>UniRef50_A2DMC1 Cluster: RasGEF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: RasGEF domain containing
protein - Trichomonas vaginalis G3
Length = 486
Score = 38.3 bits (85), Expect = 0.39
Identities = 56/241 (23%), Positives = 96/241 (39%), Gaps = 28/241 (11%)
Query: 85 YRDGQIGKAEVKDLVEKELNDMIA--LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAA 142
+ D + VKD E+ ++I V V++ W PY F + V +L +
Sbjct: 143 FTDISLPGCNVKD--NDEIKNIIRPRAVNVIKFWLKQCPYQFDKEMVKSLNIFLEALNHD 200
Query: 143 EHMESVRVEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQG-DILTLG-LTPVEL 200
+ ME++ +ST L + T + I + L+ S + TL + P EL
Sbjct: 201 KAMENLAKNVSTALNEFNGIKT-----NTTKTTIREPPPLNIPSTPPETWTLQQIEPHEL 255
Query: 201 ANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWF 260
A Q+TI H + P E + A + C I L + F
Sbjct: 256 ARQITIFHSHIFHNITPLELL---AALWGNSECGGCPNIIRLQ--------------EHF 298
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
+ LS ++ I+ K RA ++W G++ NFN L ++I + V+R+++
Sbjct: 299 DLLSRFISHSIIFPATPKERANEFKRWFEVGQQFEAQLNFNGLFSVICGITHRSVVRMEQ 358
Query: 321 T 321
T
Sbjct: 359 T 359
>UniRef50_Q5AGW7 Cluster: Putative uncharacterized protein BEM2;
n=1; Candida albicans|Rep: Putative uncharacterized
protein BEM2 - Candida albicans (Yeast)
Length = 2252
Score = 38.3 bits (85), Expect = 0.39
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
+AR++E+W+ G GN +S + I S + PV+RL K WS
Sbjct: 639 KARLLEKWIDLGCLLDKSGNMSSWLGISSVILSQPVLRLTKIWS 682
>UniRef50_P34578 Cluster: Uncharacterized protein T20G5.5; n=2;
Caenorhabditis|Rep: Uncharacterized protein T20G5.5 -
Caenorhabditis elegans
Length = 1234
Score = 38.3 bits (85), Expect = 0.39
Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL+ FN + + T+IL + R ++++++ + ++ AI L+
Sbjct: 1032 NLDLLVRRFNEVQHWSTTEILLATEEN-RMEILKKFISIATIAREYRDLLTVFAITLGLS 1090
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ + RL TWS+ + +LE ++PT NH
Sbjct: 1091 HTSISRLTLTWSKLPPASLKTFSELENLLDPTRNH 1125
>UniRef50_UPI000155BE40 Cluster: PREDICTED: similar to ras guanyl
releasing protein, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to ras guanyl releasing
protein, partial - Ornithorhynchus anatinus
Length = 340
Score = 37.5 bits (83), Expect = 0.68
Identities = 18/57 (31%), Positives = 32/57 (56%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQL 336
R V +++ + + L NFN+LMA++ L+ S + RLK+T + G+ L +L
Sbjct: 160 RRVVFVKFIHVAQGLYKLQNFNTLMAVVGGLSHSAISRLKETSAHVPPEAGKTLGEL 216
>UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;
Amniota|Rep: SH2 domain-containing protein 3C - Homo
sapiens (Human)
Length = 860
Score = 37.5 bits (83), Expect = 0.68
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 640 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 699
Query: 318 LKKTW 322
L++TW
Sbjct: 700 LEQTW 704
>UniRef50_UPI00015603B4 Cluster: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator; n=1; Equus
caballus|Rep: PREDICTED: similar to ral guanine
nucleotide dissociation stimulator - Equus caballus
Length = 361
Score = 37.1 bits (82), Expect = 0.90
Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 273 KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVM 316
+ + ++ RARV+E W+ EC L NF+SL +SAL SP +
Sbjct: 259 RSMTAQDRARVVELWIRVAEECRGLRNFSSLHTNLSAL-QSPAI 301
>UniRef50_UPI00005A5D6B Cluster: PREDICTED: similar to Ral guanine
nucleotide dissociation stimulator (RalGEF) (RalGDS);
n=1; Canis lupus familiaris|Rep: PREDICTED: similar to
Ral guanine nucleotide dissociation stimulator (RalGEF)
(RalGDS) - Canis familiaris
Length = 324
Score = 37.1 bits (82), Expect = 0.90
Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 260 FNRLSYLVATDILKGVK--SKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
FN + V T L + ++ RA V+E W+ G+ C L N++S+ AI+SAL
Sbjct: 272 FNDVVNCVITTCLGNPRMTARDRAMVVEHWIKVGKPCQILWNYSSMHAILSAL 324
>UniRef50_UPI000049A353 Cluster: hypothetical protein 66.t00031;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 66.t00031 - Entamoeba histolytica HM-1:IMSS
Length = 631
Score = 37.1 bits (82), Expect = 0.90
Identities = 20/78 (25%), Positives = 37/78 (47%)
Query: 247 TKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAI 306
T+ + +++Y W N +S VA +I + R I + + NFNS +++
Sbjct: 415 TRESSTVKSYIYWHNLISQWVAYEICRHEDIDKRYECITMFFQLLIKLIQKKNFNSFVSV 474
Query: 307 ISALNMSPVMRLKKTWSR 324
++ L V RL TW++
Sbjct: 475 MNGLKHQTVKRLMNTWNK 492
>UniRef50_UPI0000499BEE Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 1214
Score = 37.1 bits (82), Expect = 0.90
Identities = 26/110 (23%), Positives = 46/110 (41%), Gaps = 1/110 (0%)
Query: 246 DTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMA 305
D ++++ ++N + I+ + R +I+ + C L NF+SL+
Sbjct: 287 DKNACKSIQTLVKYYNGFQWYFQKRIVHCKTQEERLIIIKFLIDVANHCKILNNFDSLVC 346
Query: 306 IISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVN 355
I+ SP+ RLK T S+ + L V P N + L N +N
Sbjct: 347 IMQIFLTSPIYRLKNTISKLDNETKSKYDNLLSIVSPEHNWSILR-NLIN 395
>UniRef50_A0BXA6 Cluster: Chromosome undetermined scaffold_134,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_134,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1060
Score = 36.7 bits (81), Expect = 1.2
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 6/107 (5%)
Query: 80 KSDIEYRDGQIGKAEVK-DLVEKELNDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQ 138
K D+E R Q+ AE L+E++LN + +L ++ W S Y + ++ + + Q
Sbjct: 519 KKDLEQRSNQLNDAESTIHLMEQDLNKLSSLQEQVKAWES--KYQLQTEQFTTIREQLIQ 576
Query: 139 RCAAEHMESVRVEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQL 185
+S R E+ L +L + +LE + L+D Q+ L QL
Sbjct: 577 -SQETIKKSDRDEILNELRELQGRYQSLETQNQDLID--QLEQLRQL 620
>UniRef50_Q6BZP3 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1756
Score = 36.7 bits (81), Expect = 1.2
Identities = 15/52 (28%), Positives = 25/52 (48%)
Query: 275 VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
V S YR +++ W+ G N G+ + I + PV+RL+ +W S
Sbjct: 477 VSSAYRGKLLSHWISLGNALKNCGDMVGWLGIAGVVCSPPVLRLRDSWGFVS 528
>UniRef50_Q4P292 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1853
Score = 36.7 bits (81), Expect = 1.2
Identities = 20/62 (32%), Positives = 36/62 (58%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S V + IL K+K+RAR++E++ + N+ SL +++ L+ + V RL+
Sbjct: 1636 FNYISNWVCSMILAQSKTKHRARMLEKFFNIASILRHDNNYGSLNSVLGGLSKTAVHRLR 1695
Query: 320 KT 321
T
Sbjct: 1696 HT 1697
>UniRef50_Q9P212 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase epsilon-1; n=28; Amniota|Rep:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase epsilon-1 - Homo sapiens (Human)
Length = 2302
Score = 36.7 bits (81), Expect = 1.2
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 569 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 628
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 629 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 659
>UniRef50_UPI000049A3AF Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 910
Score = 36.3 bits (80), Expect = 1.6
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ +D N + + VA+ IL RA+++ + + FN+ NF+SL I +
Sbjct: 709 NVMRMSDRVNEICFWVASLILSFPDLNNRAKMMTKLINVAEVLFNMNNFHSLAGIYVGIE 768
Query: 312 -MSPVMRLKKT 321
S + RLKKT
Sbjct: 769 AYSSISRLKKT 779
>UniRef50_UPI000023DED7 Cluster: hypothetical protein FG06583.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG06583.1 - Gibberella zeae PH-1
Length = 1204
Score = 36.3 bits (80), Expect = 1.6
Identities = 42/181 (23%), Positives = 74/181 (40%), Gaps = 10/181 (5%)
Query: 116 WTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEESLVD 175
WT Y F D V +RS+ A+ +E V + L + +K + E Y S V
Sbjct: 228 WTYNKTYTFLDSNVWPHIRSVY----AQSVEPQLVRIGERLGRYKNKSKSAENYAASYVT 283
Query: 176 ITQVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSA 235
SS + +Q + PV+ ++Q + S V P + + P+ P ++
Sbjct: 284 GATASSFQKPTQSTTSVASVEPVKSSSQAPVATESPESVVEPSQ--EYINPVQAPPASE- 340
Query: 236 CKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMT-GREC 294
S + ++L+ + F + ATD+ + V RVI++ V T G++
Sbjct: 341 -NESANRRKAREMVAQDLDTWQTKFATQADEGATDLEERV-GDIAKRVIQEKVNTNGKQL 398
Query: 295 F 295
F
Sbjct: 399 F 399
>UniRef50_A4Y0Y3 Cluster: Tetratricopeptide TPR_2 repeat protein
precursor; n=1; Pseudomonas mendocina ymp|Rep:
Tetratricopeptide TPR_2 repeat protein precursor -
Pseudomonas mendocina ymp
Length = 294
Score = 35.9 bits (79), Expect = 2.1
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 126 DDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQL 185
DD V+A R + A E ++ R ++ST L++ + T LEQY+ L + + L
Sbjct: 45 DDLVVAF-RQLDLSLAEERLDDARSQLST-LQQRASRDTRLEQYQRQLAEAYMEQGREAL 102
Query: 186 SQGDI 190
QGD+
Sbjct: 103 QQGDL 107
>UniRef50_A2U669 Cluster: Conserved hypothetical membrane spanning
protein precursor; n=1; Bacillus coagulans 36D1|Rep:
Conserved hypothetical membrane spanning protein
precursor - Bacillus coagulans 36D1
Length = 1133
Score = 35.9 bits (79), Expect = 2.1
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 14/101 (13%)
Query: 138 QRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEESLVDI---------TQVSSLDQLSQ- 187
Q+ + ES+ E TT+ L D+LT L ESL ++ T ++ D++ +
Sbjct: 900 QKDNGQMTESMGKE-GTTVVSLGDRLTTLLATSESLKEVSEHNLHAADTVFTTFDEIDKQ 958
Query: 188 -GDILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPI 227
GDI T G T V+ AN L+ L++LS G E+F + FA +
Sbjct: 959 AGDIKTSGQTLVKRANSLSDNLLNKLS--GDEKFAKNFAGV 997
>UniRef50_Q4E1N0 Cluster: Guanine nucleotide releasing protein,
putative; n=1; Trypanosoma cruzi|Rep: Guanine nucleotide
releasing protein, putative - Trypanosoma cruzi
Length = 545
Score = 35.9 bits (79), Expect = 2.1
Identities = 20/96 (20%), Positives = 44/96 (45%)
Query: 251 RNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
RN Y D+F+ ++ V+ ++ R++ ++ ++ E L N++ L+A+ +
Sbjct: 354 RNFIQYRDFFSSVNNWVSYAVVSERDLSQRSKNLDLLMLVCDELIKLRNWDMLVALHGGM 413
Query: 311 NMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
V RL +TW+ S + +L + +H
Sbjct: 414 RAPAVKRLSRTWASLSRETAELFTRLRKMLGSDADH 449
>UniRef50_A2EWA8 Cluster: RasGEF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: RasGEF domain containing
protein - Trichomonas vaginalis G3
Length = 808
Score = 35.9 bits (79), Expect = 2.1
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N+ + FN ++ + T IL + R +I +W+ ++ +F + I AL
Sbjct: 610 NIMKMTEHFNTITSYIVTCILSKESPQERGELISRWIEIMVAALDISSFQLVFEIFGALC 669
Query: 312 MSPVMRLKKTWSRTS 326
+ RL K+W S
Sbjct: 670 NPAITRLSKSWDFVS 684
>UniRef50_A7TGB0 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 2095
Score = 35.9 bits (79), Expect = 2.1
Identities = 14/44 (31%), Positives = 28/44 (63%)
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWS 323
RA++I +W+ G + +G+ S +AI + + P++RL+ TW+
Sbjct: 581 RAKLITKWIKIGCKFEQIGDMVSWLAIATIICSLPILRLQNTWN 624
>UniRef50_Q5ZQY4 Cluster: Portal protein; n=2; root|Rep: Portal
protein - Pseudomonas phage B3
Length = 488
Score = 35.1 bits (77), Expect = 3.6
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 142 AEHMESVRVEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILTLGLTPVELA 201
AE M+ V +T L L+++ ++LE E L+D+ SLDQ +Q + GL LA
Sbjct: 416 AEAMQPVVGNWTTQLRTLIEQASSLEDLRERLLDLAPQLSLDQYAQA--MAEGLEAAHLA 473
Query: 202 NQLTIVE 208
+ + E
Sbjct: 474 GRNDVQE 480
>UniRef50_UPI0000499FDF Cluster: Ras guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Ras
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 1284
Score = 34.7 bits (76), Expect = 4.8
Identities = 25/100 (25%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Query: 246 DTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMA 305
+++C +++ A + NR+ L + IL K+R +++E G E L N++ L
Sbjct: 376 ESQC-KSILALTQFSNRVVELFSNFILSAKNLKHRIQLLEFVCQIGIEAEKLHNYDLLCC 434
Query: 306 IISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGN 345
I + S + RLK T++ + Q + +L+ P N
Sbjct: 435 ISFTFSKSAIHRLKCTFNGINEKYQQFIVRLKKISSPENN 474
>UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG06914.1 - Gibberella zeae PH-1
Length = 886
Score = 34.7 bits (76), Expect = 4.8
Identities = 24/91 (26%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 12 SCSGCNIKXXXXXXXXXXXXXXSSNHASLTSDPTLLHGTGLSYYDLSTVLTPGVKAIPNH 71
+CSG + S+ S+ S + H TG+ ++ T H
Sbjct: 721 ACSGDWVSQATSATTGKMPMSPSTRGTSIVSRDSTEHATGIPKINVDTASLKESSGTLRH 780
Query: 72 PYTNCTTE-KSDIEYRDGQIGKAEVKDLVEK 101
Y+ E +SD G IGKAE K L +K
Sbjct: 781 DYSPIDDETRSDASTTGGSIGKAEGKSLRKK 811
>UniRef50_Q0LJK2 Cluster: Penicillin-binding protein 1A; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Penicillin-binding protein 1A - Herpetosiphon
aurantiacus ATCC 23779
Length = 952
Score = 34.7 bits (76), Expect = 4.8
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 4/115 (3%)
Query: 198 VELANQLTIVELHRLSFVGPEEFVQTF--APIHPPQSTSACKTSISLHHIDTKCTRNLEA 255
V LAN + + L VG +EF++ I S++L + K A
Sbjct: 468 VALANSFNVPAVKTLDHVGIDEFLRLMQRVGISTLDDRPRYGLSLALGGGEVKLLELTTA 527
Query: 256 YADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
Y+ + N +Y AT ILK V + R V+E W ++ + N L IIS++
Sbjct: 528 YSVFANEGNYRPATTILKVVNT--RGEVLEAWSEPPKQAVLGPDGNGLAFIISSM 580
>UniRef50_Q4S6H2 Cluster: Chromosome 10 SCAF14728, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF14728, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 4678
Score = 34.3 bits (75), Expect = 6.3
Identities = 23/78 (29%), Positives = 37/78 (47%)
Query: 298 GNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFE 357
G F +LM + + +N+S L ++++ Q LR+L+ ++P A L RV
Sbjct: 3929 GQFQNLMDLKNQVNISQARELVRSYTCAVQQAVQFLRELDRSLQPCQGAAGLCSERVEET 3988
Query: 358 KCALLSKHVSTQLASRRL 375
+ ALLS Q RL
Sbjct: 3989 RRALLSLQEDFQTHVERL 4006
>UniRef50_A6Q940 Cluster: Putative uncharacterized protein; n=1;
Sulfurovum sp. NBC37-1|Rep: Putative uncharacterized
protein - Sulfurovum sp. (strain NBC37-1)
Length = 158
Score = 34.3 bits (75), Expect = 6.3
Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 156 LEKLLDKLTALEQYEESLVDIT-QVSSLDQLSQGDILTLGLTPVEL 200
LE+L+ K +YE L +T + S L +LS+GD+L LG+ +E+
Sbjct: 10 LERLMQKHQVYPEYELCLPSVTLKKSLLKKLSKGDVLLLGMQQMEM 55
>UniRef50_A3WLS4 Cluster: Hypothetical FOG: GGDEF domain protein;
n=1; Idiomarina baltica OS145|Rep: Hypothetical FOG:
GGDEF domain protein - Idiomarina baltica OS145
Length = 683
Score = 34.3 bits (75), Expect = 6.3
Identities = 21/94 (22%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 91 GKAEVKDLVEK--ELNDMIALVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESV 148
GKA +K +V+ + +R L W S F Y R D +++ S+ H ++
Sbjct: 61 GKAYLKPIVDSLSPATPLATRLRALSYWASEFAYAERYDEANSILDSLADEVKKSHDANL 120
Query: 149 RVEMSTTLEKLLDKLTALEQYEESLVDITQVSSL 182
+ E+ L +D L ++ +E+ V + + ++
Sbjct: 121 QAEL---LANRIDLLVIADKVDEAFVKVPDLEAI 151
>UniRef50_Q1E205 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1647
Score = 34.3 bits (75), Expect = 6.3
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 9/162 (5%)
Query: 200 LANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADW 259
LA Q IVE LS V ++ V S S+ T ++++ + + ++
Sbjct: 1404 LARQFAIVEQAALSEVDWKDLVDM------KWSHSSQTTLNWVNYLADQDRKGIDMVVAR 1457
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN + + I+ RA I + + + N+ +++ + AL RL
Sbjct: 1458 FNLMVKWALSQIVMTTNRALRASTITKLIHVAVYSRRIRNYATMLQMTIALCSIDCTRLV 1517
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEKCAL 361
KTW Q L+++E ++PT N L R E C L
Sbjct: 1518 KTWELVPDGEKQLLKEMERLIQPTRNFHNL---RSEMETCNL 1556
>UniRef50_A5WF04 Cluster: Putative uncharacterized protein; n=1;
Psychrobacter sp. PRwf-1|Rep: Putative uncharacterized
protein - Psychrobacter sp. PRwf-1
Length = 1211
Score = 33.9 bits (74), Expect = 8.4
Identities = 16/35 (45%), Positives = 21/35 (60%)
Query: 153 STTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQ 187
S TL++L DK+TAL Q + +V TQ S D Q
Sbjct: 1134 SDTLKELADKITALSQADNGIVSATQAQSFDAEQQ 1168
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.131 0.383
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 426,401,171
Number of Sequences: 1657284
Number of extensions: 15285131
Number of successful extensions: 39502
Number of sequences better than 10.0: 253
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 39129
Number of HSP's gapped (non-prelim): 359
length of query: 433
length of database: 575,637,011
effective HSP length: 103
effective length of query: 330
effective length of database: 404,936,759
effective search space: 133629130470
effective search space used: 133629130470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 74 (33.9 bits)
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