Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000535-TA|BGIBMGA000535-PA|IPR008937|Ras guanine
nucleotide exchange factor, IPR001895|Guanine-nucleotide dissociation
stimulator CDC25
(433 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK056257-1|BAB71130.1| 473|Homo sapiens protein ( Homo sapiens ... 209 1e-53
AC093747-1|AAY40982.1| 336|Homo sapiens unknown protein. 209 2e-53
BC121004-1|AAI21005.1| 431|Homo sapiens RASGEF1B protein protein. 207 7e-53
BC121003-1|AAI21004.1| 472|Homo sapiens RasGEF domain family, m... 207 7e-53
BC036802-1|AAH36802.1| 508|Homo sapiens RASGEF1C protein protein. 171 3e-42
AF449764-1|AAP97676.1| 466|Homo sapiens hypothetical brain prot... 171 3e-42
BC022548-1|AAH22548.2| 481|Homo sapiens RasGEF domain family, m... 155 3e-37
AK095136-1|BAC04491.1| 489|Homo sapiens protein ( Homo sapiens ... 155 3e-37
BC057759-1|AAH57759.1| 238|Homo sapiens RasGEF domain family, m... 149 1e-35
AK093160-1|BAC04079.1| 315|Homo sapiens protein ( Homo sapiens ... 149 1e-35
BC101110-1|AAI01111.2| 536|Homo sapiens Rgr protein protein. 69 3e-11
BC101109-1|AAI01110.1| 410|Homo sapiens Rgr protein protein. 69 3e-11
BC101108-1|AAI01109.1| 356|Homo sapiens Rgr protein protein. 69 3e-11
AY101396-1|AAM51551.1| 473|Homo sapiens Ral-GDS related protein... 69 3e-11
AK131340-1|BAD18497.1| 435|Homo sapiens protein ( Homo sapiens ... 69 3e-11
BC117321-1|AAI17322.1| 1486|Homo sapiens RAPGEF2 protein protein. 67 1e-10
AC074344-1|AAY40909.1| 1479|Homo sapiens unknown protein. 67 1e-10
AB002311-1|BAA20772.2| 1508|Homo sapiens KIAA0313 protein. 67 1e-10
BC047391-1|AAH47391.1| 583|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL355520-3|CAI21920.1| 583|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL355520-2|CAI21919.1| 548|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL355520-1|CAI21918.1| 279|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL162255-4|CAH71098.1| 548|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL162255-3|CAH71097.1| 583|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL162255-2|CAH71096.1| 279|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AK001106-1|BAA91506.1| 279|Homo sapiens protein ( Homo sapiens ... 66 2e-10
BC033708-1|AAH33708.1| 384|Homo sapiens RALGPS1 protein protein. 66 2e-10
AL450263-6|CAI41461.1| 557|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL450263-5|CAI41460.1| 529|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL357623-4|CAH72702.1| 384|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL357623-3|CAH72701.1| 557|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL357623-2|CAH72700.1| 529|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL357623-1|CAH72699.1| 305|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL356862-6|CAI39723.1| 213|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL356862-4|CAI39721.1| 384|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL356862-3|CAI39720.1| 557|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL356862-2|CAI39719.1| 529|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL356862-1|CAI39718.1| 305|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL160169-6|CAI40643.1| 213|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL160169-4|CAI40641.1| 384|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL160169-3|CAI40640.1| 557|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL160169-2|CAI40639.1| 529|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AL160169-1|CAI40638.1| 305|Homo sapiens Ral GEF with PH domain ... 66 2e-10
AF221098-1|AAF65253.1| 529|Homo sapiens Ral guanine nucleotide ... 66 2e-10
AB002349-1|BAA20808.2| 590|Homo sapiens KIAA0351 protein. 66 2e-10
BC032372-1|AAH32372.1| 305|Homo sapiens RALGPS1 protein protein. 66 3e-10
BC111958-1|AAI11959.1| 710|Homo sapiens ral guanine nucleotide ... 64 7e-10
BC101756-1|AAI01757.1| 710|Homo sapiens ral guanine nucleotide ... 64 7e-10
BX537416-1|CAD97658.1| 803|Homo sapiens hypothetical protein pr... 64 9e-10
AL592299-5|CAI14724.1| 768|Homo sapiens ral guanine nucleotide ... 64 9e-10
AL592299-1|CAI14720.1| 803|Homo sapiens ral guanine nucleotide ... 64 9e-10
AL590422-2|CAH73874.1| 768|Homo sapiens ral guanine nucleotide ... 64 9e-10
AL590422-1|CAH73873.1| 803|Homo sapiens ral guanine nucleotide ... 64 9e-10
AL080117-1|CAB45716.1| 754|Homo sapiens hypothetical protein pr... 64 9e-10
AF186798-2|AAG14401.1| 803|Homo sapiens RalGDS-like protein. 64 9e-10
AF186798-1|AAG14400.1| 768|Homo sapiens RalGDS-like protein. 64 9e-10
AF186780-1|AAF67281.1| 803|Homo sapiens RGL protein protein. 64 9e-10
AF186779-1|AAF67280.1| 768|Homo sapiens RGL protein protein. 64 9e-10
AB023176-1|BAA76803.1| 820|Homo sapiens KIAA0959 protein protein. 64 9e-10
BC126112-1|AAI26113.1| 1237|Homo sapiens Ras protein-specific gu... 63 2e-09
AF181250-1|AAD55268.1| 1237|Homo sapiens Ras guanine nucleotide ... 63 2e-09
AF023130-1|AAB80953.1| 1237|Homo sapiens Ras-GRF2 protein. 63 2e-09
BC059362-1|AAH59362.1| 902|Homo sapiens RALGDS protein protein. 62 4e-09
AL162417-12|CAI13417.1| 859|Homo sapiens ral guanine nucleotide... 62 4e-09
AL162417-11|CAI13415.1| 914|Homo sapiens ral guanine nucleotide... 62 4e-09
AL162417-10|CAI13416.1| 902|Homo sapiens ral guanine nucleotide... 62 4e-09
AK127524-1|BAC87018.1| 913|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AK090450-1|BAC03431.1| 625|Homo sapiens FLJ00371 protein protein. 62 4e-09
AK074114-1|BAB84940.1| 824|Homo sapiens FLJ00185 protein protein. 62 4e-09
AF295773-1|AAG02122.1| 914|Homo sapiens ral guanine nucleotide ... 62 4e-09
AF027169-1|AAQ13414.1| 859|Homo sapiens Ral guanine nucleotide ... 62 4e-09
AB037729-1|BAA92546.1| 745|Homo sapiens KIAA1308 protein protein. 62 4e-09
BC133703-1|AAI33704.1| 1504|Homo sapiens RAPGEF6 protein protein. 62 5e-09
AK074318-1|BAB85049.1| 1113|Homo sapiens protein ( Homo sapiens ... 62 5e-09
AF478567-1|AAM21637.1| 1601|Homo sapiens PDZ domain-containing g... 62 5e-09
AF478469-1|AAL79916.1| 1391|Homo sapiens Rap1 guanine nucleotide... 62 5e-09
AF478468-1|AAL79915.1| 1601|Homo sapiens Rap1 guanine nucleotide... 62 5e-09
AF394782-1|AAK83368.1| 1509|Homo sapiens rap guanine nucleotide ... 62 5e-09
AF117947-1|AAF22004.1| 1204|Homo sapiens PDZ domain-containing g... 62 5e-09
S62035-1|AAB26881.1| 489|Homo sapiens Ras-specific guanine nucl... 60 1e-08
L26584-1|AAA58417.1| 1275|Homo sapiens CDC25 protein. 60 1e-08
AK074082-1|BAB84908.1| 497|Homo sapiens FLJ00153 protein protein. 59 3e-08
BC040275-1|AAH40275.1| 1181|Homo sapiens RASGRF1 protein protein. 58 5e-08
BC027849-1|AAH27849.1| 690|Homo sapiens RAS guanyl releasing pr... 57 1e-07
AC020594-2|AAY15037.1| 690|Homo sapiens unknown protein. 57 1e-07
AB020653-1|BAA74869.2| 691|Homo sapiens KIAA0846 protein protein. 57 1e-07
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 56 2e-07
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 53 2e-06
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 53 2e-06
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 53 2e-06
Y12336-1|CAA73005.1| 609|Homo sapiens F25B3.3 kinase like prote... 53 2e-06
U78170-1|AAD12741.1| 609|Homo sapiens calcium- and diacylglycer... 53 2e-06
BC117151-1|AAI17152.1| 609|Homo sapiens RAS guanyl releasing pr... 53 2e-06
BC110306-1|AAI10307.1| 662|Homo sapiens RASGRP2 protein protein. 53 2e-06
AF081194-1|AAC79698.1| 609|Homo sapiens calcium and DAG-regulat... 53 2e-06
AF043723-1|AAF07220.1| 609|Homo sapiens guanine exchange factor... 53 2e-06
AF043722-1|AAF07219.1| 671|Homo sapiens guanine exchange factor... 53 2e-06
Z97184-2|CAB09992.1| 777|Homo sapiens RAB2, member RAS oncogene... 52 3e-06
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 52 3e-06
U68142-1|AAC50818.1| 518|Homo sapiens RalGDS-like protein. 52 3e-06
BX000343-5|CAI41832.1| 777|Homo sapiens ral guanine nucleotide ... 52 3e-06
BC032681-1|AAH32681.1| 777|Homo sapiens ral guanine nucleotide ... 52 3e-06
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 52 3e-06
BC005037-1|AAH05037.1| 644|Homo sapiens RGL2 protein protein. 52 3e-06
BC000316-1|AAH00316.1| 516|Homo sapiens RGL2 protein protein. 52 3e-06
AL662827-6|CAI17521.1| 777|Homo sapiens ral guanine nucleotide ... 52 3e-06
AL662820-6|CAI18118.1| 777|Homo sapiens ral guanine nucleotide ... 52 3e-06
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 52 3e-06
AB075513-1|BAE45759.1| 478|Homo sapiens putative protein produc... 52 3e-06
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 52 3e-06
D87467-1|BAA13406.2| 583|Homo sapiens KIAA0277 protein. 52 5e-06
D21239-1|BAA04770.1| 1077|Homo sapiens C3G protein protein. 51 9e-06
BC041710-1|AAH41710.1| 1095|Homo sapiens Rap guanine nucleotide ... 51 9e-06
AL160276-7|CAI40651.1| 1023|Homo sapiens Rap guanine nucleotide ... 51 9e-06
AL160276-3|CAI40647.1| 1094|Homo sapiens Rap guanine nucleotide ... 51 9e-06
AL160276-2|CAI40646.1| 1077|Homo sapiens Rap guanine nucleotide ... 51 9e-06
AL160271-3|CAI13383.1| 1094|Homo sapiens Rap guanine nucleotide ... 51 9e-06
AL160271-2|CAI13382.1| 1077|Homo sapiens Rap guanine nucleotide ... 51 9e-06
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 49 3e-05
AL162417-9|CAI13414.1| 309|Homo sapiens ral guanine nucleotide ... 45 5e-04
BC039203-1|AAH39203.1| 444|Homo sapiens RAPGEF5 protein protein. 45 6e-04
L13858-1|AAA35914.1| 1332|Homo sapiens guanine nucleotide exchan... 44 0.001
L13857-1|AAA35913.1| 1333|Homo sapiens guanine nucleotide exchan... 43 0.002
BC117261-1|AAI17262.1| 1332|Homo sapiens son of sevenless homolo... 43 0.002
BC115375-1|AAI15376.1| 456|Homo sapiens Rap guanine nucleotide ... 43 0.002
BC115374-1|AAI15375.1| 456|Homo sapiens Rap guanine nucleotide ... 43 0.002
AF441482-1|AAM22406.1| 1105|Homo sapiens alternate SOS1 protein. 43 0.002
AF117946-1|AAF22003.1| 456|Homo sapiens Link guanine nucleotide... 43 0.002
AC019171-1|AAX93186.1| 1304|Homo sapiens unknown protein. 43 0.002
AB209277-1|BAD92514.1| 1231|Homo sapiens son of sevenless homolo... 43 0.002
AB209140-1|BAD92377.1| 988|Homo sapiens son of sevenless homolo... 43 0.002
BC109297-1|AAI09298.1| 797|Homo sapiens RAS guanyl releasing pr... 41 0.010
BC109296-1|AAI09297.1| 797|Homo sapiens RAS guanyl releasing pr... 41 0.010
BC067298-1|AAH67298.1| 765|Homo sapiens RASGRP1 protein protein. 41 0.010
BC036784-1|AAH36784.1| 210|Homo sapiens RASGEF1B protein protein. 41 0.010
AY966005-1|AAX76907.1| 481|Homo sapiens RAS guanyl releasing pr... 41 0.010
AY954625-1|AAX54699.4| 762|Homo sapiens Ras guanyl releasing pr... 41 0.010
AY858556-1|AAW32406.2| 597|Homo sapiens RAS guanyl releasing pr... 41 0.010
AY634315-1|AAT47482.2| 546|Homo sapiens Ras guanyl releasing pr... 41 0.010
AF448437-1|AAL87858.1| 673|Homo sapiens guanyl nucleotide relea... 41 0.010
AF106071-1|AAC97349.1| 797|Homo sapiens ras activator RasGRP pr... 41 0.010
AF081197-1|AAF21898.1| 782|Homo sapiens calcium and DAG-regulat... 41 0.010
AF081195-1|AAC79699.1| 797|Homo sapiens calcium and DAG-regulat... 41 0.010
AB208848-1|BAD92085.1| 530|Homo sapiens Ras activator RasGRP va... 41 0.010
AY048121-1|AAK85703.1| 659|Homo sapiens RAS guanyl releasing pr... 40 0.013
AY048119-1|AAK85701.1| 673|Homo sapiens RAS guanyl releasing pr... 40 0.013
AL356862-5|CAI39722.1| 173|Homo sapiens Ral GEF with PH domain ... 39 0.030
AL160169-5|CAI40642.1| 173|Homo sapiens Ral GEF with PH domain ... 39 0.030
BC032365-1|AAH32365.1| 860|Homo sapiens SH2 domain containing 3... 38 0.091
BC027962-1|AAH27962.1| 703|Homo sapiens SH2D3C protein protein. 38 0.091
AY358440-1|AAQ89948.1| 703|Homo sapiens NSP3 protein. 38 0.091
AY358089-1|AAQ88456.1| 688|Homo sapiens NSP3 protein. 38 0.091
AL162586-7|CAI39766.1| 860|Homo sapiens SH2 domain containing 3... 38 0.091
AL162586-4|CAI39763.1| 703|Homo sapiens SH2 domain containing 3... 38 0.091
AL162586-2|CAI39761.1| 702|Homo sapiens SH2 domain containing 3... 38 0.091
AL162426-7|CAI41182.1| 860|Homo sapiens SH2 domain containing 3... 38 0.091
AL162426-4|CAI41179.1| 703|Homo sapiens SH2 domain containing 3... 38 0.091
AL162426-2|CAI41177.1| 702|Homo sapiens SH2 domain containing 3... 38 0.091
AF124251-1|AAD28246.1| 703|Homo sapiens SH2-containing protein ... 38 0.091
AL389885-3|CAH73289.1| 1994|Homo sapiens phospholipase C, epsilo... 37 0.16
AL389885-2|CAH73288.1| 2312|Homo sapiens phospholipase C, epsilo... 37 0.16
AL365510-3|CAH73758.1| 1994|Homo sapiens phospholipase C, epsilo... 37 0.16
AL365510-2|CAH73757.1| 2312|Homo sapiens phospholipase C, epsilo... 37 0.16
AL139124-2|CAI16675.1| 1994|Homo sapiens phospholipase C, epsilo... 37 0.16
AL139124-1|CAI16674.1| 2312|Homo sapiens phospholipase C, epsilo... 37 0.16
AL139118-2|CAH70740.1| 1994|Homo sapiens phospholipase C, epsilo... 37 0.16
AL139118-1|CAH70739.1| 2312|Homo sapiens phospholipase C, epsilo... 37 0.16
AF190642-1|AAG17145.2| 2303|Homo sapiens phosphoinositide-specif... 37 0.16
AF170071-1|AAG28341.1| 1994|Homo sapiens phospholipase C epsilon... 37 0.16
AB040949-1|BAA96040.2| 2304|Homo sapiens KIAA1516 protein protein. 37 0.16
>AK056257-1|BAB71130.1| 473|Homo sapiens protein ( Homo sapiens
cDNA FLJ31695 fis, clone NT2RI2005811, weakly similar to
CELL DIVISION CONTROL PROTEIN 25. ).
Length = 473
Score = 209 bits (511), Expect = 1e-53
Identities = 112/246 (45%), Positives = 157/246 (63%), Gaps = 20/246 (8%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
++++L +WT FPYDFRD+R+M ++ + R A+ ++ R + ++ L+ KL AL Q
Sbjct: 110 ILQLLTEWTETFPYDFRDERMMRNLKDLAHRIASGEEQTYRKNVQQMMQCLIRKLAALSQ 169
Query: 169 YEESLVDITQVSSLDQLS---------QGDILTLGLTPVELANQLTIVELHRLSFVGPEE 219
YEE L I+ S+ D+L+ Q DI+T+ P LA QLT +EL RL+++GPEE
Sbjct: 170 YEEVLAKISSTST-DRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEE 228
Query: 220 FVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKY 279
FVQ F P + +C + + K TRNLEAY +WFNRLSYLVAT+I VK K+
Sbjct: 229 FVQAFVQKDPLDNDKSC-------YSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKH 281
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELC 339
RAR+IE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++ + LE
Sbjct: 282 RARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTA---KFDILEHQ 338
Query: 340 VEPTGN 345
++P+ N
Sbjct: 339 MDPSSN 344
Score = 44.8 bits (101), Expect = 6e-04
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L+K VS + +++ + +YL P +E AL
Sbjct: 391 RLPNGHVNFEKFWELAKQVSEFMTWKQVECP-------FERDRKILQYLLTVPVFSEDAL 443
Query: 408 ELVSFEREPPVDHLEKERLKRLRGS 432
L S+E E P +H+EK+R K LR S
Sbjct: 444 YLASYESEGPENHIEKDRWKSLRSS 468
>AC093747-1|AAY40982.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 209 bits (510), Expect = 2e-53
Identities = 108/225 (48%), Positives = 149/225 (66%), Gaps = 17/225 (7%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
++++L +WT FPYDFRD+R+M ++ + R A+ ++ R + ++ L+ KL AL Q
Sbjct: 110 ILQLLTEWTETFPYDFRDERMMRNLKDLAHRIASGEEQTYRKNVQQMMQCLIRKLAALSQ 169
Query: 169 YEESLVDITQVSSLDQLS---------QGDILTLGLTPVELANQLTIVELHRLSFVGPEE 219
YEE L I+ S+ D+L+ Q DI+T+ P LA QLT +EL RL+++GPEE
Sbjct: 170 YEEVLAKISSTST-DRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEE 228
Query: 220 FVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKY 279
FVQ F P + +C + + K TRNLEAY +WFNRLSYLVAT+I VK K+
Sbjct: 229 FVQAFVQKDPLDNDKSC-------YSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKH 281
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSR 324
RAR+IE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++
Sbjct: 282 RARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAK 326
>BC121004-1|AAI21005.1| 431|Homo sapiens RASGEF1B protein protein.
Length = 431
Score = 207 bits (505), Expect = 7e-53
Identities = 113/246 (45%), Positives = 157/246 (63%), Gaps = 21/246 (8%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
++++L +WT FPYDFRD+R+M ++ + R A+ E+ R + ++ L+ KL AL Q
Sbjct: 69 ILQLLTEWTETFPYDFRDERMMRNLKDLAHRIASGE-ETYRKNVQQMMQCLIRKLAALSQ 127
Query: 169 YEESLVDITQVSSLDQLS---------QGDILTLGLTPVELANQLTIVELHRLSFVGPEE 219
YEE L I+ S+ D+L+ Q DI+T+ P LA QLT +EL RL+++GPEE
Sbjct: 128 YEEVLAKISSTST-DRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEE 186
Query: 220 FVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKY 279
FVQ F P + +C + + K TRNLEAY +WFNRLSYLVAT+I VK K+
Sbjct: 187 FVQAFVQKDPLDNDKSC-------YSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKH 239
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELC 339
RAR+IE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++ + LE
Sbjct: 240 RARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTA---KFDILEHQ 296
Query: 340 VEPTGN 345
++P+ N
Sbjct: 297 MDPSSN 302
Score = 44.8 bits (101), Expect = 6e-04
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L+K VS + +++ + +YL P +E AL
Sbjct: 349 RLPNGHVNFEKFWELAKQVSEFMTWKQVECP-------FERDRKILQYLLTVPVFSEDAL 401
Query: 408 ELVSFEREPPVDHLEKERLKRLRGS 432
L S+E E P +H+EK+R K LR S
Sbjct: 402 YLASYESEGPENHIEKDRWKSLRSS 426
>BC121003-1|AAI21004.1| 472|Homo sapiens RasGEF domain family,
member 1B protein.
Length = 472
Score = 207 bits (505), Expect = 7e-53
Identities = 113/246 (45%), Positives = 157/246 (63%), Gaps = 21/246 (8%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
++++L +WT FPYDFRD+R+M ++ + R A+ E+ R + ++ L+ KL AL Q
Sbjct: 110 ILQLLTEWTETFPYDFRDERMMRNLKDLAHRIASGE-ETYRKNVQQMMQCLIRKLAALSQ 168
Query: 169 YEESLVDITQVSSLDQLS---------QGDILTLGLTPVELANQLTIVELHRLSFVGPEE 219
YEE L I+ S+ D+L+ Q DI+T+ P LA QLT +EL RL+++GPEE
Sbjct: 169 YEEVLAKISSTST-DRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEE 227
Query: 220 FVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKY 279
FVQ F P + +C + + K TRNLEAY +WFNRLSYLVAT+I VK K+
Sbjct: 228 FVQAFVQKDPLDNDKSC-------YSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKH 280
Query: 280 RARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELC 339
RAR+IE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++ + LE
Sbjct: 281 RARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTA---KFDILEHQ 337
Query: 340 VEPTGN 345
++P+ N
Sbjct: 338 MDPSSN 343
Score = 44.8 bits (101), Expect = 6e-04
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L+K VS + +++ + +YL P +E AL
Sbjct: 390 RLPNGHVNFEKFWELAKQVSEFMTWKQVECP-------FERDRKILQYLLTVPVFSEDAL 442
Query: 408 ELVSFEREPPVDHLEKERLKRLRGS 432
L S+E E P +H+EK+R K LR S
Sbjct: 443 YLASYESEGPENHIEKDRWKSLRSS 467
>BC036802-1|AAH36802.1| 508|Homo sapiens RASGEF1C protein protein.
Length = 508
Score = 171 bits (417), Expect = 3e-42
Identities = 107/241 (44%), Positives = 135/241 (56%), Gaps = 17/241 (7%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
L+++L +WT FP DF+++ + ++ + R A E+ R M L+ L KL AL Q
Sbjct: 152 LLQLLAEWTETFPRDFQEESTIGHLKDVVGRIAPCD-EAYRKRMHQLLQALHQKLAALRQ 210
Query: 169 YEESLVDITQVSSLDQLSQGDILT--LGLT--PVELANQLTIVELHRLSFVGPEEFVQTF 224
E LV + S I LG+ P LA QLT VEL RL +GPEEFVQ F
Sbjct: 211 GPEGLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAF 270
Query: 225 APIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVI 284
P ST C + T NLEAY WFNRL YLVAT+I K K RA+VI
Sbjct: 271 VNKDPLASTKPCFSDK---------TSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVI 321
Query: 285 EQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTG 344
E ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++ + LE ++PTG
Sbjct: 322 EFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVRTA---KFFILEHQMDPTG 378
Query: 345 N 345
N
Sbjct: 379 N 379
Score = 40.7 bits (91), Expect = 0.010
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L+K V + +++ + YL P +E L
Sbjct: 426 RLPNGHVNFEKFLELAKQVGEFITWKQVECP-------FEQDASITHYLYTAPIFSEDGL 478
Query: 408 ELVSFEREPPVDHLEKERLKRLRGS 432
L S+E E P + EKER K LR S
Sbjct: 479 YLASYESESPENQTEKERWKALRSS 503
>AF449764-1|AAP97676.1| 466|Homo sapiens hypothetical brain protein
protein.
Length = 466
Score = 171 bits (417), Expect = 3e-42
Identities = 107/241 (44%), Positives = 135/241 (56%), Gaps = 17/241 (7%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQ 168
L+++L +WT FP DF+++ + ++ + R A E+ R M L+ L KL AL Q
Sbjct: 110 LLQLLAEWTETFPRDFQEESTIGHLKDVVGRIAPCD-EAYRKRMHQLLQALHQKLAALRQ 168
Query: 169 YEESLVDITQVSSLDQLSQGDILT--LGLT--PVELANQLTIVELHRLSFVGPEEFVQTF 224
E LV + S I LG+ P LA QLT VEL RL +GPEEFVQ F
Sbjct: 169 GPEGLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAF 228
Query: 225 APIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVI 284
P ST C + T NLEAY WFNRL YLVAT+I K K RA+VI
Sbjct: 229 VNKDPLASTKPCFSDK---------TSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVI 279
Query: 285 EQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTG 344
E ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++ + LE ++PTG
Sbjct: 280 EFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVRTA---KFFILEHQMDPTG 336
Query: 345 N 345
N
Sbjct: 337 N 337
Score = 40.7 bits (91), Expect = 0.010
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L+K V + +++ + YL P +E L
Sbjct: 384 RLPNGHVNFEKFLELAKQVGEFITWKQVECP-------FEQDASITHYLYTAPIFSEDGL 436
Query: 408 ELVSFEREPPVDHLEKERLKRLRGS 432
L S+E E P + EKER K LR S
Sbjct: 437 YLASYESESPENQTEKERWKALRSS 461
>BC022548-1|AAH22548.2| 481|Homo sapiens RasGEF domain family,
member 1A protein.
Length = 481
Score = 155 bits (376), Expect = 3e-37
Identities = 95/248 (38%), Positives = 149/248 (60%), Gaps = 23/248 (9%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAA--EHMESVRVEMSTTLEKLLDKLTAL 166
+V++L++WT FPYDF+D++ MA +++IT R E +V+ ++ + LL L A
Sbjct: 117 IVQLLKEWTEAFPYDFQDEKAMAELKAITHRVTQCDEENGTVKKAIAQMTQSLLLSLAAR 176
Query: 167 EQYEESLVDITQVSSLDQ---------LSQGDILTLGLTPVELANQLTIVELHRLSFVGP 217
Q +E L + + ++D+ +Q DIL + P+ LA QLT +EL R+S + P
Sbjct: 177 SQLQE-LREKLRPPAVDKGPILKTKPPAAQKDILGVCCDPLVLAQQLTHIELDRVSSIYP 235
Query: 218 EEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKS 277
E+ +Q + + + C+ + TK T +LEAY +WFN LS LVAT++ + VK
Sbjct: 236 EDLMQIVSHMDSLDN-HRCRGDL------TK-TYSLEAYDNWFNCLSMLVATEVCRVVKK 287
Query: 278 KYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLE 337
K+R R++E ++ RECFN+GNFNS+MAIIS +N+SPV RLKKTWS+ + LE
Sbjct: 288 KHRTRMLEFFIDVARECFNIGNFNSMMAIISGMNLSPVARLKKTWSKVKTA---KFDVLE 344
Query: 338 LCVEPTGN 345
++P+ N
Sbjct: 345 HHMDPSSN 352
Score = 34.7 bits (76), Expect = 0.64
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 395 YLNDRPTLTEPALELVSFEREPPVDHLEKERLKRLR 430
YL P +E AL + SFE E P +H+EK+ K LR
Sbjct: 439 YLLTAPIYSEEALFVASFESEGPENHVEKDSWKTLR 474
>AK095136-1|BAC04491.1| 489|Homo sapiens protein ( Homo sapiens
cDNA FLJ37817 fis, clone BRSSN2003820. ).
Length = 489
Score = 155 bits (376), Expect = 3e-37
Identities = 95/248 (38%), Positives = 149/248 (60%), Gaps = 23/248 (9%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAA--EHMESVRVEMSTTLEKLLDKLTAL 166
+V++L++WT FPYDF+D++ MA +++IT R E +V+ ++ + LL L A
Sbjct: 125 IVQLLKEWTEAFPYDFQDEKAMAELKAITHRVTQCDEENGTVKKAIAQMTQSLLLSLAAR 184
Query: 167 EQYEESLVDITQVSSLDQ---------LSQGDILTLGLTPVELANQLTIVELHRLSFVGP 217
Q +E L + + ++D+ +Q DIL + P+ LA QLT +EL R+S + P
Sbjct: 185 SQLQE-LREKLRPPAVDKGPILKTKPPAAQKDILGVCCDPLVLAQQLTHIELDRVSSIYP 243
Query: 218 EEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKS 277
E+ +Q + + + C+ + TK T +LEAY +WFN LS LVAT++ + VK
Sbjct: 244 EDLMQIVSHMDSLDN-HRCRGDL------TK-TYSLEAYDNWFNCLSMLVATEVCRVVKK 295
Query: 278 KYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLE 337
K+R R++E ++ RECFN+GNFNS+MAIIS +N+SPV RLKKTWS+ + LE
Sbjct: 296 KHRTRMLEFFIDVARECFNIGNFNSMMAIISGMNLSPVARLKKTWSKVKTA---KFDVLE 352
Query: 338 LCVEPTGN 345
++P+ N
Sbjct: 353 HHMDPSSN 360
Score = 35.1 bits (77), Expect = 0.49
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 395 YLNDRPTLTEPALELVSFEREPPVDHLEKERLKRLR 430
YL P +E AL + SFE E P +H+EK+ K LR
Sbjct: 447 YLLTAPIYSEEALFVASFESEGPENHMEKDSWKTLR 482
>BC057759-1|AAH57759.1| 238|Homo sapiens RasGEF domain family,
member 1C protein.
Length = 238
Score = 149 bits (362), Expect = 1e-35
Identities = 95/198 (47%), Positives = 111/198 (56%), Gaps = 16/198 (8%)
Query: 152 MSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILT--LGLT--PVELANQLTIV 207
M L+ L KL AL Q E LV + S I LG+ P LA QLT V
Sbjct: 1 MHQLLQALHQKLAALRQGPEGLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHV 60
Query: 208 ELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLV 267
EL RL +GPEEFVQ F P ST C + T NLEAY WFNRL YLV
Sbjct: 61 ELERLRHIGPEEFVQAFVNKDPLASTKPCFSDK---------TSNLEAYVKWFNRLCYLV 111
Query: 268 ATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSA 327
AT+I K K RA+VIE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++
Sbjct: 112 ATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVRT 171
Query: 328 VCGQQLRQLELCVEPTGN 345
+ LE ++PTGN
Sbjct: 172 A---KFFILEHQMDPTGN 186
>AK093160-1|BAC04079.1| 315|Homo sapiens protein ( Homo sapiens
cDNA FLJ35841 fis, clone TESTI2006665, weakly similar to
CELL DIVISION CONTROL PROTEIN 25. ).
Length = 315
Score = 149 bits (362), Expect = 1e-35
Identities = 95/198 (47%), Positives = 111/198 (56%), Gaps = 16/198 (8%)
Query: 152 MSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQGDILT--LGLT--PVELANQLTIV 207
M L+ L KL AL Q E LV + S I LG+ P LA QLT V
Sbjct: 1 MHQLLQALHQKLAALRQGPEGLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHV 60
Query: 208 ELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLV 267
EL RL +GPEEFVQ F P ST C + T NLEAY WFNRL YLV
Sbjct: 61 ELERLRHIGPEEFVQAFVNKDPLASTKPCFSDK---------TSNLEAYVKWFNRLCYLV 111
Query: 268 ATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSA 327
AT+I K K RA+VIE ++ RECFN+GNFNSLMAIIS +NMSPV RLKKTW++
Sbjct: 112 ATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVRT 171
Query: 328 VCGQQLRQLELCVEPTGN 345
+ LE ++PTGN
Sbjct: 172 A---KFFILEHQMDPTGN 186
Score = 40.7 bits (91), Expect = 0.010
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
Query: 348 RLSGNRVNFEKCALLSKHVSTQLASRRLTTDQXXXXXXXXXXXXVWRYLNDRPTLTEPAL 407
RL VNFEK L+K V + +++ + YL P +E L
Sbjct: 233 RLPNGHVNFEKFLELAKQVGEFITWKQVECP-------FEQDASITHYLYTAPIFSEDGL 285
Query: 408 ELVSFEREPPVDHLEKERLKRLRGS 432
L S+E E P + EKER K LR S
Sbjct: 286 YLASYESESPENQTEKERWKALRSS 310
>BC101110-1|AAI01111.2| 536|Homo sapiens Rgr protein protein.
Length = 536
Score = 68.9 bits (161), Expect = 3e-11
Identities = 34/86 (39%), Positives = 55/86 (63%), Gaps = 4/86 (4%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRL+ + T L ++++ RARV+E W+ REC +L NF+S+ I+SAL +P+ +
Sbjct: 270 FNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQ 329
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPT 343
L KTW+ S+ ++L+ ELC + T
Sbjct: 330 LHKTWAGVSSKSMKELK--ELCKKDT 353
>BC101109-1|AAI01110.1| 410|Homo sapiens Rgr protein protein.
Length = 410
Score = 68.9 bits (161), Expect = 3e-11
Identities = 34/86 (39%), Positives = 55/86 (63%), Gaps = 4/86 (4%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRL+ + T L ++++ RARV+E W+ REC +L NF+S+ I+SAL +P+ +
Sbjct: 134 FNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQ 193
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPT 343
L KTW+ S+ ++L+ ELC + T
Sbjct: 194 LHKTWAGVSSKSMKELK--ELCKKDT 217
>BC101108-1|AAI01109.1| 356|Homo sapiens Rgr protein protein.
Length = 356
Score = 68.9 bits (161), Expect = 3e-11
Identities = 34/86 (39%), Positives = 55/86 (63%), Gaps = 4/86 (4%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRL+ + T L ++++ RARV+E W+ REC +L NF+S+ I+SAL +P+ +
Sbjct: 134 FNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQ 193
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPT 343
L KTW+ S+ ++L+ ELC + T
Sbjct: 194 LHKTWAGVSSKSMKELK--ELCKKDT 217
>AY101396-1|AAM51551.1| 473|Homo sapiens Ral-GDS related protein
Rgr protein.
Length = 473
Score = 68.9 bits (161), Expect = 3e-11
Identities = 34/86 (39%), Positives = 55/86 (63%), Gaps = 4/86 (4%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRL+ + T L ++++ RARV+E W+ REC +L NF+S+ I+SAL +P+ +
Sbjct: 270 FNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQ 329
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPT 343
L KTW+ S+ ++L+ ELC + T
Sbjct: 330 LHKTWAGVSSKSMKELK--ELCKKDT 353
>AK131340-1|BAD18497.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ16354 fis, clone TESTI4000319, weakly similar
to GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR RALGDS
FORM B. ).
Length = 435
Score = 68.9 bits (161), Expect = 3e-11
Identities = 34/86 (39%), Positives = 55/86 (63%), Gaps = 4/86 (4%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FNRL+ + T L ++++ RARV+E W+ REC +L NF+S+ I+SAL +P+ +
Sbjct: 270 FNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQ 329
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPT 343
L KTW+ S+ ++L+ ELC + T
Sbjct: 330 LHKTWAGVSSKSMKELK--ELCKKDT 353
>BC117321-1|AAI17322.1| 1486|Homo sapiens RAPGEF2 protein protein.
Length = 1486
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 22/198 (11%)
Query: 156 LEKLLDKLTALEQY--EESLVDITQVSSLDQ---LSQGDILTLGLTPVELANQLTIVELH 210
L KL D++ +Y + ++ T S D L + I L L+ VE+A QL++
Sbjct: 660 LSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFE 719
Query: 211 RLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATD 270
+ P E++ + +S ++C NL+ + + N+ ++ VA++
Sbjct: 720 LFRNIEPTEYIDDLFKL---RSKTSCA--------------NLKRFEEVINQETFWVASE 762
Query: 271 ILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCG 330
IL+ R ++I+ ++ C NFNS+ AIIS LN++PV RL+ TW +
Sbjct: 763 ILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYE 822
Query: 331 QQLRQLELCVEPTGNHAR 348
+ + L+ +P+ N A+
Sbjct: 823 KLFQDLQDLFDPSRNMAK 840
>AC074344-1|AAY40909.1| 1479|Homo sapiens unknown protein.
Length = 1479
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 22/198 (11%)
Query: 156 LEKLLDKLTALEQY--EESLVDITQVSSLDQ---LSQGDILTLGLTPVELANQLTIVELH 210
L KL D++ +Y + ++ T S D L + I L L+ VE+A QL++
Sbjct: 652 LSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFE 711
Query: 211 RLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATD 270
+ P E++ + +S ++C NL+ + + N+ ++ VA++
Sbjct: 712 LFRNIEPTEYIDDLFKL---RSKTSCA--------------NLKRFEEVINQETFWVASE 754
Query: 271 ILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCG 330
IL+ R ++I+ ++ C NFNS+ AIIS LN++PV RL+ TW +
Sbjct: 755 ILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYE 814
Query: 331 QQLRQLELCVEPTGNHAR 348
+ + L+ +P+ N A+
Sbjct: 815 KLFQDLQDLFDPSRNMAK 832
>AB002311-1|BAA20772.2| 1508|Homo sapiens KIAA0313 protein.
Length = 1508
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 22/198 (11%)
Query: 156 LEKLLDKLTALEQY--EESLVDITQVSSLDQ---LSQGDILTLGLTPVELANQLTIVELH 210
L KL D++ +Y + ++ T S D L + I L L+ VE+A QL++
Sbjct: 681 LSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFE 740
Query: 211 RLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATD 270
+ P E++ + +S ++C NL+ + + N+ ++ VA++
Sbjct: 741 LFRNIEPTEYIDDLFKL---RSKTSCA--------------NLKRFEEVINQETFWVASE 783
Query: 271 ILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCG 330
IL+ R ++I+ ++ C NFNS+ AIIS LN++PV RL+ TW +
Sbjct: 784 ILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYE 843
Query: 331 QQLRQLELCVEPTGNHAR 348
+ + L+ +P+ N A+
Sbjct: 844 KLFQDLQDLFDPSRNMAK 861
>BC047391-1|AAH47391.1| 583|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 2 protein.
Length = 583
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 89 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 148
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 149 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 186
>AL355520-3|CAI21920.1| 583|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 2 protein.
Length = 583
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 89 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 148
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 149 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 186
>AL355520-2|CAI21919.1| 548|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 2 protein.
Length = 548
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 54 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 113
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 114 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 151
>AL355520-1|CAI21918.1| 279|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 2 protein.
Length = 279
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 89 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 148
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 149 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 186
>AL162255-4|CAH71098.1| 548|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 2 protein.
Length = 548
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 54 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 113
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 114 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 151
>AL162255-3|CAH71097.1| 583|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 2 protein.
Length = 583
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 89 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 148
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 149 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 186
>AL162255-2|CAH71096.1| 279|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 2 protein.
Length = 279
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 89 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 148
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 149 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 186
>AK001106-1|BAA91506.1| 279|Homo sapiens protein ( Homo sapiens
cDNA FLJ10244 fis, clone HEMBB1000632, weakly similar to
GUANINE NUCLEOTIDE RELEASING PROTEIN. ).
Length = 279
Score = 66.5 bits (155), Expect = 2e-10
Identities = 32/98 (32%), Positives = 52/98 (53%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
N A+ FN +S+ V +IL K RA V+ ++ T ++ + L N ++LMA++S L
Sbjct: 89 NAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQ 148
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
+P+ RL KTW+ S +LE + N+ RL
Sbjct: 149 SAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRL 186
>BC033708-1|AAH33708.1| 384|Homo sapiens RALGPS1 protein protein.
Length = 384
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL450263-6|CAI41461.1| 557|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 557
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL450263-5|CAI41460.1| 529|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 529
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL357623-4|CAH72702.1| 384|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 384
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL357623-3|CAH72701.1| 557|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 557
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL357623-2|CAH72700.1| 529|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 529
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL357623-1|CAH72699.1| 305|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 305
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL356862-6|CAI39723.1| 213|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 213
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL356862-4|CAI39721.1| 384|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 384
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL356862-3|CAI39720.1| 557|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 557
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL356862-2|CAI39719.1| 529|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 529
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL356862-1|CAI39718.1| 305|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 305
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL160169-6|CAI40643.1| 213|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 213
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL160169-4|CAI40641.1| 384|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 384
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL160169-3|CAI40640.1| 557|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 557
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL160169-2|CAI40639.1| 529|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 529
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AL160169-1|CAI40638.1| 305|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 305
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AF221098-1|AAF65253.1| 529|Homo sapiens Ral guanine nucleotide
exchange factor RalGPS1A protein.
Length = 529
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>AB002349-1|BAA20808.2| 590|Homo sapiens KIAA0351 protein.
Length = 590
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 80 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKH---SLAPN 123
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 124 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 183
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 184 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 219
>BC032372-1|AAH32372.1| 305|Homo sapiens RALGPS1 protein protein.
Length = 305
Score = 65.7 bits (153), Expect = 3e-10
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 193 LGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTKCTRN 252
L +TP E A+Q+T++++ + PEE ++C S H N
Sbjct: 47 LKVTPEEFASQITLMDIPVFKAIQPEEL-------------ASCGWSKKEKHT---LAPN 90
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
+ A+ FN++S+ V +IL K RA ++ +V ++ L N +SLM+++SAL
Sbjct: 91 VVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQS 150
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
+P+ RL KTW+ + +L+ + N+ R
Sbjct: 151 APIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 186
>BC111958-1|AAI11959.1| 710|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 3 protein.
Length = 710
Score = 64.5 bits (150), Expect = 7e-10
Identities = 79/292 (27%), Positives = 125/292 (42%), Gaps = 43/292 (14%)
Query: 89 QIGKAEVKDLVEKELNDMIALVRVLRQWTSMFPYDFRDDRV---MALVRSITQRCAAEHM 145
+I K V+DL + ++ A+V VL W P DFRD V + VR+ A
Sbjct: 126 EIKKTAVQDLSFNK--NLRAVVSVLGSWLQDHPQDFRDPPVHSDLGSVRTFLGWAAPGSA 183
Query: 146 ESVRVEMSTTLEKLLDKLTALEQYEESLV-----DITQVSSLDQ-----------LSQGD 189
E+ + E LE L++ ++ E V + Q S D + QG
Sbjct: 184 EAQKAEK--LLEDFLEEAEREQEEEPPQVWTGPPRVAQTSDPDSSEACAEEEEGLMPQGP 241
Query: 190 ILTLGLTPVELANQLTIVELHRLSFVGPEEFV-QTFAPIHPPQSTSACKTSISLHHIDTK 248
L L + E+A QLT+++L S V E + ++ P + A T
Sbjct: 242 QL-LDFSVDEVAEQLTLIDLELFSKVRLYECLGSVWSQRDRPGAAGASPT---------- 290
Query: 249 CTRNLEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAI 306
+ A FN ++ V +L G+ + RA+ +E+W+ + C L NF+SL AI
Sbjct: 291 ----VRATVAQFNTVTGCVLGSVLGAPGLAAPQRAQRLEKWIRIAQRCRELRNFSSLRAI 346
Query: 307 ISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEK 358
+SAL +P+ RLK++W S R+L NH LS + F++
Sbjct: 347 LSALQSNPIYRLKRSWGAVSREPLSTFRKLSQIFSDENNH--LSSREILFQE 396
>BC101756-1|AAI01757.1| 710|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 3 protein.
Length = 710
Score = 64.5 bits (150), Expect = 7e-10
Identities = 79/292 (27%), Positives = 125/292 (42%), Gaps = 43/292 (14%)
Query: 89 QIGKAEVKDLVEKELNDMIALVRVLRQWTSMFPYDFRDDRV---MALVRSITQRCAAEHM 145
+I K V+DL + ++ A+V VL W P DFRD V + VR+ A
Sbjct: 126 EIKKTAVQDLSFNK--NLRAVVSVLGSWLQDHPQDFRDPPVHSDLGSVRTFLGWAAPGSA 183
Query: 146 ESVRVEMSTTLEKLLDKLTALEQYEESLV-----DITQVSSLDQ-----------LSQGD 189
E+ + E LE L++ ++ E V + Q S D + QG
Sbjct: 184 EAQKAEK--LLEDFLEEAEREQEEEPPQVWTGPPRVAQTSDPDSSEACAEEEEGLMPQGP 241
Query: 190 ILTLGLTPVELANQLTIVELHRLSFVGPEEFV-QTFAPIHPPQSTSACKTSISLHHIDTK 248
L L + E+A QLT+++L S V E + ++ P + A T
Sbjct: 242 QL-LDFSVDEVAEQLTLIDLELFSKVRLYECLGSVWSQRDRPGAAGASPT---------- 290
Query: 249 CTRNLEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAI 306
+ A FN ++ V +L G+ + RA+ +E+W+ + C L NF+SL AI
Sbjct: 291 ----VRATVAQFNTVTGCVLGSVLGAPGLAAPQRAQRLEKWIRIAQRCRELRNFSSLRAI 346
Query: 307 ISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEK 358
+SAL +P+ RLK++W S R+L NH LS + F++
Sbjct: 347 LSALQSNPIYRLKRSWGAVSREPLSTFRKLSQIFSDENNH--LSSREILFQE 396
>BX537416-1|CAD97658.1| 803|Homo sapiens hypothetical protein
protein.
Length = 803
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 311 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 370
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 371 QSNSIYRLKKTWA 383
>AL592299-5|CAI14724.1| 768|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 1 protein.
Length = 768
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 276 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 335
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 336 QSNSIYRLKKTWA 348
>AL592299-1|CAI14720.1| 803|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 1 protein.
Length = 803
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 311 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 370
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 371 QSNSIYRLKKTWA 383
>AL590422-2|CAH73874.1| 768|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 1 protein.
Length = 768
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 276 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 335
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 336 QSNSIYRLKKTWA 348
>AL590422-1|CAH73873.1| 803|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 1 protein.
Length = 803
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 311 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 370
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 371 QSNSIYRLKKTWA 383
>AL080117-1|CAB45716.1| 754|Homo sapiens hypothetical protein
protein.
Length = 754
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 262 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 321
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 322 QSNSIYRLKKTWA 334
>AF186798-2|AAG14401.1| 803|Homo sapiens RalGDS-like protein.
Length = 803
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 311 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 370
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 371 QSNSIYRLKKTWA 383
>AF186798-1|AAG14400.1| 768|Homo sapiens RalGDS-like protein.
Length = 768
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 276 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 335
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 336 QSNSIYRLKKTWA 348
>AF186780-1|AAF67281.1| 803|Homo sapiens RGL protein protein.
Length = 803
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 311 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 370
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 371 QSNSIYRLKKTWA 383
>AF186779-1|AAF67280.1| 768|Homo sapiens RGL protein protein.
Length = 768
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 276 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 335
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 336 QSNSIYRLKKTWA 348
>AB023176-1|BAA76803.1| 820|Homo sapiens KIAA0959 protein protein.
Length = 820
Score = 64.1 bits (149), Expect = 9e-10
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 253 LEAYADWFNRLSYLVATDILKG--VKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN L+ V + IL G +K++ RA++IE+W+ EC L NF+SL AI+SAL
Sbjct: 328 IRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSAL 387
Query: 311 NMSPVMRLKKTWS 323
+ + RLKKTW+
Sbjct: 388 QSNSIYRLKKTWA 400
>BC126112-1|AAI26113.1| 1237|Homo sapiens Ras protein-specific guanine
nucleotide-releasing factor 2 protein.
Length = 1237
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/90 (37%), Positives = 47/90 (52%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S LVA+ I+ RA IE+WV C L N+N ++ I SALN S + RLK
Sbjct: 1050 FNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLK 1109
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW++ S + +L+ V G L
Sbjct: 1110 KTWAKVSKQTKALMDKLQKTVSSEGRFKNL 1139
>AF181250-1|AAD55268.1| 1237|Homo sapiens Ras guanine nucleotide
exchange factor 2 protein.
Length = 1237
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/90 (37%), Positives = 47/90 (52%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S LVA+ I+ RA IE+WV C L N+N ++ I SALN S + RLK
Sbjct: 1050 FNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLK 1109
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW++ S + +L+ V G L
Sbjct: 1110 KTWAKVSKQTKALMDKLQKTVSSEGRFKNL 1139
>AF023130-1|AAB80953.1| 1237|Homo sapiens Ras-GRF2 protein.
Length = 1237
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/90 (37%), Positives = 47/90 (52%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S LVA+ I+ RA IE+WV C L N+N ++ I SALN S + RLK
Sbjct: 1050 FNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLK 1109
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW++ S + +L+ V G L
Sbjct: 1110 KTWAKVSKQTKALMDKLQKTVSSEGRFKNL 1139
>BC059362-1|AAH59362.1| 902|Homo sapiens RALGDS protein protein.
Length = 902
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 418 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 477
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 478 QSNSIHRLKKTWEDVS 493
>AL162417-12|CAI13417.1| 859|Homo sapiens ral guanine nucleotide
dissociation stimulator protein.
Length = 859
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 375 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 434
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 435 QSNSIHRLKKTWEDVS 450
>AL162417-11|CAI13415.1| 914|Homo sapiens ral guanine nucleotide
dissociation stimulator protein.
Length = 914
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 430 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 489
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 490 QSNSIHRLKKTWEDVS 505
>AL162417-10|CAI13416.1| 902|Homo sapiens ral guanine nucleotide
dissociation stimulator protein.
Length = 902
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 418 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 477
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 478 QSNSIHRLKKTWEDVS 493
>AK127524-1|BAC87018.1| 913|Homo sapiens protein ( Homo sapiens
cDNA FLJ45617 fis, clone BRTHA3026916, highly similar
to Ral guanine nucleotide dissociation stimulator. ).
Length = 913
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 429 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 488
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 489 QSNSIHRLKKTWEDVS 504
>AK090450-1|BAC03431.1| 625|Homo sapiens FLJ00371 protein protein.
Length = 625
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 219 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 278
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 279 QSNSIHRLKKTWEDVS 294
>AK074114-1|BAB84940.1| 824|Homo sapiens FLJ00185 protein protein.
Length = 824
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 418 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 477
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 478 QSNSIHRLKKTWEDVS 493
>AF295773-1|AAG02122.1| 914|Homo sapiens ral guanine nucleotide
dissociation stimulator protein.
Length = 914
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 430 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 489
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 490 QSNSIHRLKKTWEDVS 505
>AF027169-1|AAQ13414.1| 859|Homo sapiens Ral guanine nucleotide
dissociation stimulator A protein.
Length = 859
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 375 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 434
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 435 QSNSIHRLKKTWEDVS 450
>AB037729-1|BAA92546.1| 745|Homo sapiens KIAA1308 protein protein.
Length = 745
Score = 62.1 bits (144), Expect = 4e-09
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 253 LEAYADWFNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISAL 310
+ A FN ++ V T L + K+ RARV+E W+ REC L NF+SL AI+SAL
Sbjct: 226 IRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSAL 285
Query: 311 NMSPVMRLKKTWSRTS 326
+ + RLKKTW S
Sbjct: 286 QSNSIHRLKKTWEDVS 301
>BC133703-1|AAI33704.1| 1504|Homo sapiens RAPGEF6 protein protein.
Length = 1504
Score = 61.7 bits (143), Expect = 5e-09
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 899 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 958
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 959 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 995
>AK074318-1|BAB85049.1| 1113|Homo sapiens protein ( Homo sapiens
cDNA FLJ23738 fis, clone HEP15081, highly similar to PDZ
domain-containing guanine nucleotide exchange factor I.
).
Length = 1113
Score = 61.7 bits (143), Expect = 5e-09
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 613 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 672
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 673 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 709
>AF478567-1|AAM21637.1| 1601|Homo sapiens PDZ domain-containing
guanine nucleotide exchange factor PDZ-GEF2 protein.
Length = 1601
Score = 61.7 bits (143), Expect = 5e-09
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 899 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 958
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 959 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 995
>AF478469-1|AAL79916.1| 1391|Homo sapiens Rap1 guanine
nucleotide-exchange factor PDZ-GEF2B protein.
Length = 1391
Score = 61.7 bits (143), Expect = 5e-09
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 899 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 958
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 959 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 995
>AF478468-1|AAL79915.1| 1601|Homo sapiens Rap1 guanine
nucleotide-exchange factor PDZ-GEF2A protein.
Length = 1601
Score = 61.7 bits (143), Expect = 5e-09
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 899 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 958
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 959 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 995
>AF394782-1|AAK83368.1| 1509|Homo sapiens rap guanine nucleotide
exchange factor protein.
Length = 1509
Score = 61.7 bits (143), Expect = 5e-09
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 904 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 963
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 964 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 1000
>AF117947-1|AAF22004.1| 1204|Homo sapiens PDZ domain-containing
guanine nucleotide exchange factor I protein.
Length = 1204
Score = 61.7 bits (143), Expect = 5e-09
Identities = 30/97 (30%), Positives = 55/97 (56%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
+L+ + D N+ ++ VA++IL R ++I+ ++ C NFNS+ AIIS LN
Sbjct: 949 HLKRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLN 1008
Query: 312 MSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ V RL+ TW + + + L+ L+ +P+ N A+
Sbjct: 1009 LASVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAK 1045
>S62035-1|AAB26881.1| 489|Homo sapiens Ras-specific guanine
nucleotide-releasing factor protein.
Length = 489
Score = 60.5 bits (140), Expect = 1e-08
Identities = 30/90 (33%), Positives = 48/90 (53%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S L+A++I++ R IE+WV C L N+N+++ I S++N S + RLK
Sbjct: 302 FNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLK 361
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW + S + +L+ V G L
Sbjct: 362 KTWLKVSKQTKALIDKLQKLVSSEGRFKNL 391
>L26584-1|AAA58417.1| 1275|Homo sapiens CDC25 protein.
Length = 1275
Score = 60.5 bits (140), Expect = 1e-08
Identities = 30/90 (33%), Positives = 48/90 (53%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S L+A++I++ R IE+WV C L N+N+++ I S++N S + RLK
Sbjct: 1088 FNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLK 1147
Query: 320 KTWSRTSAVCGQQLRQLELCVEPTGNHARL 349
KTW + S + +L+ V G L
Sbjct: 1148 KTWLKVSKQTKALIDKLQKLVSSEGRFKNL 1177
>AK074082-1|BAB84908.1| 497|Homo sapiens FLJ00153 protein protein.
Length = 497
Score = 59.3 bits (137), Expect = 3e-08
Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 4/101 (3%)
Query: 260 FNRLSYLVATDIL--KGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMR 317
FN ++ V +L G+ + RA+ +E+W+ + C L NF+SL AI+SAL +P+ R
Sbjct: 95 FNTVTGCVLGSVLGAPGLAAPQRAQRLEKWIRIAQRCRELRNFSSLRAILSALQSNPIYR 154
Query: 318 LKKTWSRTSAVCGQQLRQLELCVEPTGNHARLSGNRVNFEK 358
LK++W S R+L NH LS + F++
Sbjct: 155 LKRSWGAVSREPLSTFRKLSQIFSDENNH--LSSREILFQE 193
>BC040275-1|AAH40275.1| 1181|Homo sapiens RASGRF1 protein protein.
Length = 1181
Score = 58.4 bits (135), Expect = 5e-08
Identities = 26/67 (38%), Positives = 41/67 (61%)
Query: 260 FNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLK 319
FN +S L+A++I++ R IE+WV C L N+N+++ I S++N S + RLK
Sbjct: 1070 FNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLK 1129
Query: 320 KTWSRTS 326
KTW + S
Sbjct: 1130 KTWLKVS 1136
>BC027849-1|AAH27849.1| 690|Homo sapiens RAS guanyl releasing
protein 3 (calcium and DAG-regulated) protein.
Length = 690
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/237 (25%), Positives = 103/237 (43%), Gaps = 33/237 (13%)
Query: 113 LRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEES 172
+R W FP +F D + L+R E V ++ L ++++ Y+
Sbjct: 78 MRYWILKFPAEFNLD--LGLIRM------TEEFREVASQLGYEKHVSLIDISSIPSYDW- 128
Query: 173 LVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVE---LHRLSFVGPEEFVQTFAPIHP 229
+ +TQ + + + +L L P+ELA LT +E R+SF + +V IH
Sbjct: 129 MRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV-----IH- 182
Query: 230 PQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVM 289
C ++ T LE FN +S V +L + RA VI +++
Sbjct: 183 -----GC--------LENNPT--LERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFIN 227
Query: 290 TGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
++ L NFN+LMA++ L+ S + RLK+T S S+ + ++ V GN+
Sbjct: 228 VAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNY 284
>AC020594-2|AAY15037.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/237 (25%), Positives = 103/237 (43%), Gaps = 33/237 (13%)
Query: 113 LRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEES 172
+R W FP +F D + L+R E V ++ L ++++ Y+
Sbjct: 78 MRYWILKFPAEFNLD--LGLIRM------TEEFREVASQLGYEKHVSLIDISSIPSYDW- 128
Query: 173 LVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVE---LHRLSFVGPEEFVQTFAPIHP 229
+ +TQ + + + +L L P+ELA LT +E R+SF + +V IH
Sbjct: 129 MRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV-----IH- 182
Query: 230 PQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVM 289
C ++ T LE FN +S V +L + RA VI +++
Sbjct: 183 -----GC--------LENNPT--LERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFIN 227
Query: 290 TGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
++ L NFN+LMA++ L+ S + RLK+T S S+ + ++ V GN+
Sbjct: 228 VAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNY 284
>AB020653-1|BAA74869.2| 691|Homo sapiens KIAA0846 protein protein.
Length = 691
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/237 (25%), Positives = 103/237 (43%), Gaps = 33/237 (13%)
Query: 113 LRQWTSMFPYDFRDDRVMALVRSITQRCAAEHMESVRVEMSTTLEKLLDKLTALEQYEES 172
+R W FP +F D + L+R E V ++ L ++++ Y+
Sbjct: 80 MRYWILKFPAEFNLD--LGLIRM------TEEFREVASQLGYEKHVSLIDISSIPSYDW- 130
Query: 173 LVDITQVSSLDQLSQGDILTLGLTPVELANQLTIVE---LHRLSFVGPEEFVQTFAPIHP 229
+ +TQ + + + +L L P+ELA LT +E R+SF + +V IH
Sbjct: 131 MRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV-----IH- 184
Query: 230 PQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVM 289
C ++ T LE FN +S V +L + RA VI +++
Sbjct: 185 -----GC--------LENNPT--LERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFIN 229
Query: 290 TGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
++ L NFN+LMA++ L+ S + RLK+T S S+ + ++ V GN+
Sbjct: 230 VAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNY 286
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 56.4 bits (130), Expect = 2e-07
Identities = 31/103 (30%), Positives = 50/103 (48%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H+ T NLE + FN L Y VAT++ RA+++++++ N NS
Sbjct: 653 HLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLKKFIKLAAHLKEQKNVNSF 712
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A++ L+ SP+ RL TW R + LE ++P+ NH
Sbjct: 713 FAVMFGLSNSPISRLAHTWERLPHKVRKLYSALERLLDPSWNH 755
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 53.2 bits (122), Expect = 2e-06
Identities = 30/103 (29%), Positives = 48/103 (46%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H+ T NLE + FN L Y VAT++ RA+++ +++ N NS
Sbjct: 653 HLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSF 712
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A++ L+ S + RL TW R + LE ++P+ NH
Sbjct: 713 FAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNH 755
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 53.2 bits (122), Expect = 2e-06
Identities = 30/103 (29%), Positives = 48/103 (46%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H+ T NLE + FN L Y VAT++ RA+++ +++ N NS
Sbjct: 653 HLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSF 712
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A++ L+ S + RL TW R + LE ++P+ NH
Sbjct: 713 FAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNH 755
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 53.2 bits (122), Expect = 2e-06
Identities = 30/103 (29%), Positives = 48/103 (46%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H+ T NLE + FN L Y VAT++ RA+++ +++ N NS
Sbjct: 653 HLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSF 712
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A++ L+ S + RL TW R + LE ++P+ NH
Sbjct: 713 FAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNH 755
>Y12336-1|CAA73005.1| 609|Homo sapiens F25B3.3 kinase like protein
protein.
Length = 609
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 169 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 228
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 229 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 286
>U78170-1|AAD12741.1| 609|Homo sapiens calcium- and
diacylglycerol-regulated guanine nucleotide exchange
factor I protein.
Length = 609
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 169 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 228
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 229 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 286
>BC117151-1|AAI17152.1| 609|Homo sapiens RAS guanyl releasing
protein 2 (calcium and DAG-regulated) protein.
Length = 609
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 169 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 228
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 229 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 286
>BC110306-1|AAI10307.1| 662|Homo sapiens RASGRP2 protein protein.
Length = 662
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 222 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 281
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 282 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 339
>AF081194-1|AAC79698.1| 609|Homo sapiens calcium and DAG-regulated
guanine nucleotide exchange factor I protein.
Length = 609
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 169 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 228
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 229 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 286
>AF043723-1|AAF07220.1| 609|Homo sapiens guanine exchange factor
MCG7 isoform 2 protein.
Length = 609
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 169 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 228
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 229 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 286
>AF043722-1|AAF07219.1| 671|Homo sapiens guanine exchange factor
MCG7 isoform 1 protein.
Length = 671
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Query: 234 SACKTSISLHH--IDTKCTRN---LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWV 288
S CK +H + CT + LE + FN +S V IL + RA VI +V
Sbjct: 231 SFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFV 290
Query: 289 MTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
+ L NFN+LMA++ L+ S + RLK+T S S + L V TGN+
Sbjct: 291 HVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNY 348
>Z97184-2|CAB09992.1| 777|Homo sapiens RAB2, member RAS oncogene
family-like protein.
Length = 777
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 320 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 374
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 52.4 bits (120), Expect = 3e-06
Identities = 27/103 (26%), Positives = 49/103 (47%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H K T NL+ + FN + + V T+I + R +++++++ C N NS
Sbjct: 804 HNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 863
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
AI+ L+ V RL TW + + + + E ++P+ NH
Sbjct: 864 FAIVMGLSNIAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNH 906
>U68142-1|AAC50818.1| 518|Homo sapiens RalGDS-like protein.
Length = 518
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 42 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 96
>BX000343-5|CAI41832.1| 777|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 2 protein.
Length = 777
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 320 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 374
>BC032681-1|AAH32681.1| 777|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 2 protein.
Length = 777
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 320 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 374
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 52.4 bits (120), Expect = 3e-06
Identities = 27/103 (26%), Positives = 49/103 (47%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H K T NL+ + FN + + V T+I + R +++++++ C N NS
Sbjct: 804 HNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 863
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
AI+ L+ V RL TW + + + + E ++P+ NH
Sbjct: 864 FAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNH 906
>BC005037-1|AAH05037.1| 644|Homo sapiens RGL2 protein protein.
Length = 644
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 187 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 241
>BC000316-1|AAH00316.1| 516|Homo sapiens RGL2 protein protein.
Length = 516
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 59 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 113
>AL662827-6|CAI17521.1| 777|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 2 protein.
Length = 777
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 320 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 374
>AL662820-6|CAI18118.1| 777|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 2 protein.
Length = 777
Score = 52.4 bits (120), Expect = 3e-06
Identities = 20/55 (36%), Positives = 35/55 (63%)
Query: 272 LKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
++ ++ RAR++E+W+ EC L NF+S+ A++SAL SP+ RL+ W +
Sbjct: 320 IRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEAT 374
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 52.4 bits (120), Expect = 3e-06
Identities = 27/103 (26%), Positives = 49/103 (47%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H K T NL+ + FN + + V T+I + R +++++++ C N NS
Sbjct: 436 HNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 495
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
AI+ L+ V RL TW + + + + E ++P+ NH
Sbjct: 496 FAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNH 538
>AB075513-1|BAE45759.1| 478|Homo sapiens putative protein product
of Nbla00496 protein.
Length = 478
Score = 52.4 bits (120), Expect = 3e-06
Identities = 27/103 (26%), Positives = 49/103 (47%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H K T NL+ + FN + + V T+I + R +++++++ C N NS
Sbjct: 271 HNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 330
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
AI+ L+ V RL TW + + + + E ++P+ NH
Sbjct: 331 FAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNH 373
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 52.4 bits (120), Expect = 3e-06
Identities = 27/103 (26%), Positives = 49/103 (47%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H K T NL+ + FN + + V T+I + R +++++++ C N NS
Sbjct: 804 HNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 863
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
AI+ L+ V RL TW + + + + E ++P+ NH
Sbjct: 864 FAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNH 906
>D87467-1|BAA13406.2| 583|Homo sapiens KIAA0277 protein.
Length = 583
Score = 51.6 bits (118), Expect = 5e-06
Identities = 28/97 (28%), Positives = 46/97 (47%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NL N + VAT+IL + R +++++++ C N NS AI+
Sbjct: 386 TANLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMG 445
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
LN + V RL +TW + + +LE +P+ NH
Sbjct: 446 LNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNH 482
>D21239-1|BAA04770.1| 1077|Homo sapiens C3G protein protein.
Length = 1077
Score = 50.8 bits (116), Expect = 9e-06
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 878 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 937
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 938 SAPIRRLE--WQKQTS 951
>BC041710-1|AAH41710.1| 1095|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 1 protein.
Length = 1095
Score = 50.8 bits (116), Expect = 9e-06
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 896 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 955
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 956 SAPIRRLE--WQKQTS 969
>AL160276-7|CAI40651.1| 1023|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 1 protein.
Length = 1023
Score = 50.8 bits (116), Expect = 9e-06
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 824 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 883
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 884 SAPIRRLE--WQKQTS 897
>AL160276-3|CAI40647.1| 1094|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 1 protein.
Length = 1094
Score = 50.8 bits (116), Expect = 9e-06
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 895 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 954
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 955 SAPIRRLE--WQKQTS 968
>AL160276-2|CAI40646.1| 1077|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 1 protein.
Length = 1077
Score = 50.8 bits (116), Expect = 9e-06
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 878 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 937
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 938 SAPIRRLE--WQKQTS 951
>AL160271-3|CAI13383.1| 1094|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 1 protein.
Length = 1094
Score = 50.8 bits (116), Expect = 9e-06
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 895 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 954
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 955 SAPIRRLE--WQKQTS 968
>AL160271-2|CAI13382.1| 1077|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 1 protein.
Length = 1077
Score = 50.8 bits (116), Expect = 9e-06
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Query: 252 NLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALN 311
NL + + FN +SY V + I+ K++ R R++ +++ + L NFNS +AI+SAL+
Sbjct: 878 NLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALD 937
Query: 312 MSPVMRLKKTWSRTSA 327
+P+ RL+ W + ++
Sbjct: 938 SAPIRRLE--WQKQTS 951
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 49.2 bits (112), Expect = 3e-05
Identities = 26/103 (25%), Positives = 48/103 (46%)
Query: 244 HIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSL 303
H K T NL+ + FN + + V T+I + R +++++++ C N NS
Sbjct: 660 HNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 719
Query: 304 MAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
AI+ L+ V RL TW + + + + E ++ + NH
Sbjct: 720 FAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDTSRNH 762
>AL162417-9|CAI13414.1| 309|Homo sapiens ral guanine nucleotide
dissociation stimulator protein.
Length = 309
Score = 45.2 bits (102), Expect = 5e-04
Identities = 22/44 (50%), Positives = 28/44 (63%)
Query: 283 VIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
V EQ+ + EC L NF+SL AI+SAL + + RLKKTW S
Sbjct: 22 VAEQFTLMDAECRILKNFSSLYAILSALQSNSIHRLKKTWEDVS 65
>BC039203-1|AAH39203.1| 444|Homo sapiens RAPGEF5 protein protein.
Length = 444
Score = 44.8 bits (101), Expect = 6e-04
Identities = 22/80 (27%), Positives = 40/80 (50%)
Query: 267 VATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTS 326
+A +IL + R +++++++ C N NS AI+ LN + V RL +TW +
Sbjct: 264 IAQEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIP 323
Query: 327 AVCGQQLRQLELCVEPTGNH 346
+ +LE +P+ NH
Sbjct: 324 GKFKKLFSELESLTDPSLNH 343
>L13858-1|AAA35914.1| 1332|Homo sapiens guanine nucleotide exchange
factor protein.
Length = 1332
Score = 43.6 bits (98), Expect = 0.001
Identities = 56/246 (22%), Positives = 104/246 (42%), Gaps = 27/246 (10%)
Query: 107 IALVRVLRQWTSMFPYDFRDD-----RVMALVRSITQRCAAEHMESVRVEMSTTLEKLLD 161
+ ++ V R W YDF D R+ + + S+ + + +ES+ + + +
Sbjct: 685 LRVLNVFRHWVDHHYYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQAN 744
Query: 162 KLTALEQYEESLVDIT-QVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEF 220
++ +E I +S Q D++TL P+E+A QLT++E V P E
Sbjct: 745 GVSHNITFESPPPPIEWHISKPGQFETFDLMTLD--PIEIARQLTLLESDLYRKVQPSEL 802
Query: 221 VQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYR 280
V + + S + H T NL WF + I++ + R
Sbjct: 803 VGSVWTKEDKEINSPNLLKMIRH------TTNLTL---WFEKC-------IVEAENFEER 846
Query: 281 ARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCV 340
V+ + + + +L NFN ++ I+SA+N V RL T+ A+ ++ + L+ V
Sbjct: 847 VAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTF---EALQERKRKILDEAV 903
Query: 341 EPTGNH 346
E + +H
Sbjct: 904 ELSQDH 909
>L13857-1|AAA35913.1| 1333|Homo sapiens guanine nucleotide exchange
factor protein.
Length = 1333
Score = 43.2 bits (97), Expect = 0.002
Identities = 66/278 (23%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 78 TEKSDIEYRDG-QIGKAEVKDLVEKELNDM-IALVRVLRQWTSMFPYDFRDD-----RVM 130
TE I +G Q AE+K ++ + + + ++ V R W YDF D R+
Sbjct: 656 TEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRME 715
Query: 131 ALVRSITQRCAAEHMESVR--VEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQG 188
+ ++ + + +ES+ ++ Q V+ +S +
Sbjct: 716 EFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVE-WHISRPGHIETF 774
Query: 189 DILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTK 248
D+LTL P+E+A QLT++E V P E V + + S + H
Sbjct: 775 DLLTLH--PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRH----- 827
Query: 249 CTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIIS 308
T NL WF + +V T+ L+ R V+ + + + L NFN ++ ++S
Sbjct: 828 -TTNLTL---WFEKC--IVETENLEE-----RVAVVSRIIEILQVFQELNNFNGVLEVVS 876
Query: 309 ALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A+N SPV RL T+ + + +Q + LE E + +H
Sbjct: 877 AMNSSPVYRLDHTFEQ---IPSRQKKILEEAHELSEDH 911
>BC117261-1|AAI17262.1| 1332|Homo sapiens son of sevenless homolog 2
(Drosophila) protein.
Length = 1332
Score = 43.2 bits (97), Expect = 0.002
Identities = 56/246 (22%), Positives = 104/246 (42%), Gaps = 27/246 (10%)
Query: 107 IALVRVLRQWTSMFPYDFRDD-----RVMALVRSITQRCAAEHMESVRVEMSTTLEKLLD 161
+ ++ V R W YDF D R+ + + S+ + + +ES+ + + +
Sbjct: 685 LRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQAN 744
Query: 162 KLTALEQYEESLVDIT-QVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEF 220
++ +E I +S Q D++TL P+E+A QLT++E V P E
Sbjct: 745 GVSHNITFESPPPPIEWHISKPGQFETFDLMTLH--PIEIARQLTLLESDLYRKVQPSEL 802
Query: 221 VQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYR 280
V + + S + H T NL WF + I++ + R
Sbjct: 803 VGSVWTKEDKEINSPNLLKMIRH------TTNLTL---WFEKC-------IVEAENFEER 846
Query: 281 ARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCV 340
V+ + + + +L NFN ++ I+SA+N V RL T+ A+ ++ + L+ V
Sbjct: 847 VAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTF---EALQERKRKILDEAV 903
Query: 341 EPTGNH 346
E + +H
Sbjct: 904 ELSQDH 909
>BC115375-1|AAI15376.1| 456|Homo sapiens Rap guanine nucleotide
exchange factor (GEF)-like 1 protein.
Length = 456
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/97 (24%), Positives = 46/97 (47%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NLE + +++ VAT++L RA+++++++ C + S A++
Sbjct: 256 TANLELLLQRCSEVTHWVATEVLLCEAPGKRAQLLKKFIKIAALCKQNQDLLSFYAVVMG 315
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
L+ + V RL+ TW + R+ E +P NH
Sbjct: 316 LDNAAVSRLRLTWEKLPGKFKNLFRKFENLTDPCRNH 352
>BC115374-1|AAI15375.1| 456|Homo sapiens Rap guanine nucleotide
exchange factor (GEF)-like 1 protein.
Length = 456
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/97 (24%), Positives = 46/97 (47%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NLE + +++ VAT++L RA+++++++ C + S A++
Sbjct: 256 TANLELLLQRCSEVTHWVATEVLLCEAPGKRAQLLKKFIKIAALCKQNQDLLSFYAVVMG 315
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
L+ + V RL+ TW + R+ E +P NH
Sbjct: 316 LDNAAVSRLRLTWEKLPGKFKNLFRKFENLTDPCRNH 352
>AF441482-1|AAM22406.1| 1105|Homo sapiens alternate SOS1 protein.
Length = 1105
Score = 43.2 bits (97), Expect = 0.002
Identities = 66/278 (23%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 78 TEKSDIEYRDG-QIGKAEVKDLVEKELNDM-IALVRVLRQWTSMFPYDFRDD-----RVM 130
TE I +G Q AE+K ++ + + + ++ V R W YDF D R+
Sbjct: 656 TEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRME 715
Query: 131 ALVRSITQRCAAEHMESVR--VEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQG 188
+ ++ + + +ES+ ++ Q V+ +S +
Sbjct: 716 EFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVE-WHISRPGHIETF 774
Query: 189 DILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTK 248
D+LTL P+E+A QLT++E V P E V + + S + H
Sbjct: 775 DLLTLH--PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRH----- 827
Query: 249 CTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIIS 308
T NL WF + +V T+ L+ R V+ + + + L NFN ++ ++S
Sbjct: 828 -TTNLTL---WFEKC--IVETENLEE-----RVAVVSRIIEILQVFQELNNFNGVLEVVS 876
Query: 309 ALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A+N SPV RL T+ + + +Q + LE E + +H
Sbjct: 877 AMNSSPVYRLDHTFEQ---IPSRQKKILEEAHELSEDH 911
>AF117946-1|AAF22003.1| 456|Homo sapiens Link guanine nucleotide
exchange factor II protein.
Length = 456
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/97 (24%), Positives = 46/97 (47%)
Query: 250 TRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISA 309
T NLE + +++ VAT++L RA+++++++ C + S A++
Sbjct: 256 TANLELLLQRCSEVTHWVATEVLLCEAPGKRAQLLKKFIKIAALCKQNQDLLSFYAVVMG 315
Query: 310 LNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
L+ + V RL+ TW + R+ E +P NH
Sbjct: 316 LDNAAVSRLRLTWEKLPGKFKNLFRKFENLTDPCRNH 352
>AC019171-1|AAX93186.1| 1304|Homo sapiens unknown protein.
Length = 1304
Score = 43.2 bits (97), Expect = 0.002
Identities = 66/278 (23%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 78 TEKSDIEYRDG-QIGKAEVKDLVEKELNDM-IALVRVLRQWTSMFPYDFRDD-----RVM 130
TE I +G Q AE+K ++ + + + ++ V R W YDF D R+
Sbjct: 627 TEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRME 686
Query: 131 ALVRSITQRCAAEHMESVR--VEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQG 188
+ ++ + + +ES+ ++ Q V+ +S +
Sbjct: 687 EFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVE-WHISRPGHIETF 745
Query: 189 DILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTK 248
D+LTL P+E+A QLT++E V P E V + + S + H
Sbjct: 746 DLLTLH--PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRH----- 798
Query: 249 CTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIIS 308
T NL WF + +V T+ L+ R V+ + + + L NFN ++ ++S
Sbjct: 799 -TTNLTL---WFEKC--IVETENLEE-----RVAVVSRIIEILQVFQELNNFNGVLEVVS 847
Query: 309 ALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A+N SPV RL T+ + + +Q + LE E + +H
Sbjct: 848 AMNSSPVYRLDHTFEQ---IPSRQKKILEEAHELSEDH 882
>AB209277-1|BAD92514.1| 1231|Homo sapiens son of sevenless homolog 2
variant protein.
Length = 1231
Score = 43.2 bits (97), Expect = 0.002
Identities = 56/246 (22%), Positives = 104/246 (42%), Gaps = 27/246 (10%)
Query: 107 IALVRVLRQWTSMFPYDFRDD-----RVMALVRSITQRCAAEHMESVRVEMSTTLEKLLD 161
+ ++ V R W YDF D R+ + + S+ + + +ES+ + + +
Sbjct: 715 LRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQAN 774
Query: 162 KLTALEQYEESLVDIT-QVSSLDQLSQGDILTLGLTPVELANQLTIVELHRLSFVGPEEF 220
++ +E I +S Q D++TL P+E+A QLT++E V P E
Sbjct: 775 GVSHNITFESPPPPIEWHISKPGQFETFDLMTLH--PIEIARQLTLLESDLYRKVQPSEL 832
Query: 221 VQTFAPIHPPQSTSACKTSISLHHIDTKCTRNLEAYADWFNRLSYLVATDILKGVKSKYR 280
V + + S + H T NL WF + I++ + R
Sbjct: 833 VGSVWTKEDKEINSPNLLKMIRH------TTNLTL---WFEKC-------IVEAENFEER 876
Query: 281 ARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCV 340
V+ + + + +L NFN ++ I+SA+N V RL T+ A+ ++ + L+ V
Sbjct: 877 VAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTF---EALQERKRKILDEAV 933
Query: 341 EPTGNH 346
E + +H
Sbjct: 934 ELSQDH 939
>AB209140-1|BAD92377.1| 988|Homo sapiens son of sevenless homolog 1
variant protein.
Length = 988
Score = 43.2 bits (97), Expect = 0.002
Identities = 66/278 (23%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 78 TEKSDIEYRDG-QIGKAEVKDLVEKELNDM-IALVRVLRQWTSMFPYDFRDD-----RVM 130
TE I +G Q AE+K ++ + + + ++ V R W YDF D R+
Sbjct: 326 TEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRME 385
Query: 131 ALVRSITQRCAAEHMESVR--VEMSTTLEKLLDKLTALEQYEESLVDITQVSSLDQLSQG 188
+ ++ + + +ES+ ++ Q V+ +S +
Sbjct: 386 EFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVE-WHISRPGHIETF 444
Query: 189 DILTLGLTPVELANQLTIVELHRLSFVGPEEFVQTFAPIHPPQSTSACKTSISLHHIDTK 248
D+LTL P+E+A QLT++E V P E V + + S + H
Sbjct: 445 DLLTLH--PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRH----- 497
Query: 249 CTRNLEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIIS 308
T NL WF + +V T+ L+ R V+ + + + L NFN ++ ++S
Sbjct: 498 -TTNLTL---WFEKC--IVETENLEE-----RVAVVSRIIEILQVFQELNNFNGVLEVVS 546
Query: 309 ALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNH 346
A+N SPV RL T+ + + +Q + LE E + +H
Sbjct: 547 AMNSSPVYRLDHTFEQ---IPSRQKKILEEAHELSEDH 581
>BC109297-1|AAI09298.1| 797|Homo sapiens RAS guanyl releasing
protein 1 (calcium and DAG-regulated) protein.
Length = 797
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>BC109296-1|AAI09297.1| 797|Homo sapiens RAS guanyl releasing
protein 1 (calcium and DAG-regulated) protein.
Length = 797
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>BC067298-1|AAH67298.1| 765|Homo sapiens RASGRP1 protein protein.
Length = 765
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>BC036784-1|AAH36784.1| 210|Homo sapiens RASGEF1B protein protein.
Length = 210
Score = 40.7 bits (91), Expect = 0.010
Identities = 14/34 (41%), Positives = 25/34 (73%)
Query: 109 LVRVLRQWTSMFPYDFRDDRVMALVRSITQRCAA 142
++++L +WT FPYDFRD+R+M ++ + R A+
Sbjct: 110 ILQLLTEWTETFPYDFRDERMMRNLKDLAHRIAS 143
>AY966005-1|AAX76907.1| 481|Homo sapiens RAS guanyl releasing
protein I splice variant C protein.
Length = 481
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>AY954625-1|AAX54699.4| 762|Homo sapiens Ras guanyl releasing
protein I splice variant A protein.
Length = 762
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>AY858556-1|AAW32406.2| 597|Homo sapiens RAS guanyl releasing
protein I splice variant B protein.
Length = 597
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>AY634315-1|AAT47482.2| 546|Homo sapiens Ras guanyl releasing
protein I splice variant D protein.
Length = 546
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>AF448437-1|AAL87858.1| 673|Homo sapiens guanyl nucleotide
releasing protein 4 protein.
Length = 673
Score = 40.7 bits (91), Expect = 0.010
Identities = 27/96 (28%), Positives = 45/96 (46%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
LE N +S V +L RA+V+++++ + L NFN+LMA+ L
Sbjct: 240 LEGSVGLSNSVSRWVQVMVLSRPGPLQRAQVLDKFIHVAQRLHQLQNFNTLMAVTGGLCH 299
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
S + RLK + + S + L +L + N+AR
Sbjct: 300 SAISRLKDSHAHLSPDSTKALLELTELLASHNNYAR 335
>AF106071-1|AAC97349.1| 797|Homo sapiens ras activator RasGRP
protein.
Length = 797
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>AF081197-1|AAF21898.1| 782|Homo sapiens calcium and DAG-regulated
guanine nucleotide exchange factor II protein.
Length = 782
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 237 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 296
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 297 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 344
>AF081195-1|AAC79699.1| 797|Homo sapiens calcium and DAG-regulated
guanine nucleotide exchange factor II protein.
Length = 797
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 252 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 311
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 312 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 359
>AB208848-1|BAD92085.1| 530|Homo sapiens Ras activator RasGRP
variant protein.
Length = 530
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 261 NRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNMSPVMRLKK 320
N +S V +L + RA V +++ ++ L NFN+LMA+I L S + RLK+
Sbjct: 20 NGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKE 79
Query: 321 TWSRTSAVCGQQLRQLELCVEPT---GNHARLSGNRVNFEKCALLSKHV 366
T S + L ++ + + N+ R G +F K +L H+
Sbjct: 80 TSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF-KIPILGVHL 127
>AY048121-1|AAK85703.1| 659|Homo sapiens RAS guanyl releasing
protein 4 variant 2 protein.
Length = 659
Score = 40.3 bits (90), Expect = 0.013
Identities = 27/96 (28%), Positives = 45/96 (46%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
LE N +S V +L RA+V+++++ + L NFN+LMA+ L
Sbjct: 226 LEGSVGLSNSVSRWVQVMVLSCPGPLQRAQVLDKFIHVAQRLHQLQNFNTLMAVTGGLCH 285
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
S + RLK + + S + L +L + N+AR
Sbjct: 286 SAISRLKDSHAHLSPDSTKALLELTELLASHNNYAR 321
>AY048119-1|AAK85701.1| 673|Homo sapiens RAS guanyl releasing
protein 4 protein.
Length = 673
Score = 40.3 bits (90), Expect = 0.013
Identities = 27/96 (28%), Positives = 45/96 (46%)
Query: 253 LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQWVMTGRECFNLGNFNSLMAIISALNM 312
LE N +S V +L RA+V+++++ + L NFN+LMA+ L
Sbjct: 240 LEGSVGLSNSVSRWVQVMVLSCPGPLQRAQVLDKFIHVAQRLHQLQNFNTLMAVTGGLCH 299
Query: 313 SPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
S + RLK + + S + L +L + N+AR
Sbjct: 300 SAISRLKDSHAHLSPDSTKALLELTELLASHNNYAR 335
>AL356862-5|CAI39722.1| 173|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 173
Score = 39.1 bits (87), Expect = 0.030
Identities = 17/57 (29%), Positives = 31/57 (54%)
Query: 292 RECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ L N +SLM+++SAL +P+ RL KTW+ + +L+ + N+ R
Sbjct: 100 QKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 156
>AL160169-5|CAI40642.1| 173|Homo sapiens Ral GEF with PH domain and
SH3 binding motif 1 protein.
Length = 173
Score = 39.1 bits (87), Expect = 0.030
Identities = 17/57 (29%), Positives = 31/57 (54%)
Query: 292 RECFNLGNFNSLMAIISALNMSPVMRLKKTWSRTSAVCGQQLRQLELCVEPTGNHAR 348
++ L N +SLM+++SAL +P+ RL KTW+ + +L+ + N+ R
Sbjct: 100 QKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKR 156
>BC032365-1|AAH32365.1| 860|Homo sapiens SH2 domain containing 3C
protein.
Length = 860
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 640 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 699
Query: 318 LKKTW 322
L++TW
Sbjct: 700 LEQTW 704
>BC027962-1|AAH27962.1| 703|Homo sapiens SH2D3C protein protein.
Length = 703
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 483 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 542
Query: 318 LKKTW 322
L++TW
Sbjct: 543 LEQTW 547
>AY358440-1|AAQ89948.1| 703|Homo sapiens NSP3 protein.
Length = 703
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 483 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 542
Query: 318 LKKTW 322
L++TW
Sbjct: 543 LEQTW 547
>AY358089-1|AAQ88456.1| 688|Homo sapiens NSP3 protein.
Length = 688
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 468 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 527
Query: 318 LKKTW 322
L++TW
Sbjct: 528 LEQTW 532
>AL162586-7|CAI39766.1| 860|Homo sapiens SH2 domain containing 3C
protein.
Length = 860
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 640 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 699
Query: 318 LKKTW 322
L++TW
Sbjct: 700 LEQTW 704
>AL162586-4|CAI39763.1| 703|Homo sapiens SH2 domain containing 3C
protein.
Length = 703
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 483 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 542
Query: 318 LKKTW 322
L++TW
Sbjct: 543 LEQTW 547
>AL162586-2|CAI39761.1| 702|Homo sapiens SH2 domain containing 3C
protein.
Length = 702
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 482 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 541
Query: 318 LKKTW 322
L++TW
Sbjct: 542 LEQTW 546
>AL162426-7|CAI41182.1| 860|Homo sapiens SH2 domain containing 3C
protein.
Length = 860
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 640 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 699
Query: 318 LKKTW 322
L++TW
Sbjct: 700 LEQTW 704
>AL162426-4|CAI41179.1| 703|Homo sapiens SH2 domain containing 3C
protein.
Length = 703
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 483 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 542
Query: 318 LKKTW 322
L++TW
Sbjct: 543 LEQTW 547
>AL162426-2|CAI41177.1| 702|Homo sapiens SH2 domain containing 3C
protein.
Length = 702
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 482 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 541
Query: 318 LKKTW 322
L++TW
Sbjct: 542 LEQTW 546
>AF124251-1|AAD28246.1| 703|Homo sapiens SH2-containing protein
Nsp3 protein.
Length = 703
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 260 FNRLSYLVATDILKGVKS-KYRARVIEQWVMTGRECFN-LGNFNSLMAIISALNMSPVMR 317
F+ +S ++A DIL S + RA ++ + + E +GN S A++ AL+M+ + R
Sbjct: 483 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISR 542
Query: 318 LKKTW 322
L++TW
Sbjct: 543 LEQTW 547
>AL389885-3|CAH73289.1| 1994|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 1994
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 261 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 320
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 321 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 351
>AL389885-2|CAH73288.1| 2312|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 2312
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 569 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 628
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 629 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 659
>AL365510-3|CAH73758.1| 1994|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 1994
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 261 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 320
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 321 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 351
>AL365510-2|CAH73757.1| 2312|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 2312
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 569 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 628
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 629 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 659
>AL139124-2|CAI16675.1| 1994|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 1994
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 261 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 320
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 321 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 351
>AL139124-1|CAI16674.1| 2312|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 2312
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 569 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 628
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 629 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 659
>AL139118-2|CAH70740.1| 1994|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 1994
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 261 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 320
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 321 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 351
>AL139118-1|CAH70739.1| 2312|Homo sapiens phospholipase C, epsilon 1
protein.
Length = 2312
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 569 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 628
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 629 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 659
>AF190642-1|AAG17145.2| 2303|Homo sapiens phosphoinositide-specific
phospholipase C PLC-epsilon protein.
Length = 2303
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 569 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 628
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 629 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 659
>AF170071-1|AAG28341.1| 1994|Homo sapiens phospholipase C epsilon
protein.
Length = 1994
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 261 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 320
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 321 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 351
>AB040949-1|BAA96040.2| 2304|Homo sapiens KIAA1516 protein protein.
Length = 2304
Score = 36.7 bits (81), Expect = 0.16
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 231 QSTSAC-KTSISLHHIDTKCTRN--LEAYADWFNRLSYLVATDILKGVKSKYRARVIEQW 287
QS+ C K SIS + T+ + LE FN +S V IL + + V
Sbjct: 571 QSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYL 630
Query: 288 VMTGRECFNLGNFNSLMAIISALNMSPVMRL 318
V + C+N+GN+N++M ++ L V+++
Sbjct: 631 VHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM 661
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.131 0.383
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 56,429,921
Number of Sequences: 224733
Number of extensions: 2009491
Number of successful extensions: 4459
Number of sequences better than 10.0: 170
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 4215
Number of HSP's gapped (non-prelim): 215
length of query: 433
length of database: 73,234,838
effective HSP length: 92
effective length of query: 341
effective length of database: 52,559,402
effective search space: 17922756082
effective search space used: 17922756082
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 67 (31.1 bits)
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