Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000529-TA|BGIBMGA000529-PA|IPR006025|Peptidase M,
neutral zinc metallopeptidases, zinc-binding site, IPR000718|Peptidase
M13, neprilysin, IPR008753|Peptidase M13
(761 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF521189-1|AAM77664.1| 811|Homo sapiens endothelin-converting e... 512 e-144
AF428264-1|AAL30387.1| 736|Homo sapiens endothelin converting e... 512 e-144
AF428263-1|AAL30386.1| 787|Homo sapiens endothelin converting e... 512 e-144
AF192531-1|AAG28399.1| 765|Homo sapiens endothelin-converting e... 512 e-144
AB011176-1|BAA25530.2| 773|Homo sapiens KIAA0604 protein protein. 512 e-144
AY359003-1|AAQ89362.1| 736|Homo sapiens ECE2 protein. 511 e-144
BC101027-1|AAI01028.2| 770|Homo sapiens membrane metallo-endope... 510 e-144
AL831784-1|CAI17336.1| 779|Homo sapiens mel transforming oncoge... 510 e-144
AL589746-1|CAI22652.1| 779|Homo sapiens mel transforming oncoge... 510 e-144
AF336981-1|AAL08942.1| 770|Homo sapiens neprilysin-like metallo... 510 e-144
BC101030-1|AAI01031.2| 770|Homo sapiens membrane metallo-endope... 509 e-143
Y00811-1|CAA68752.1| 750|Homo sapiens protein ( Human mRNA for ... 503 e-141
X07166-1|CAA30157.1| 743|Homo sapiens protein ( Human mRNA for ... 503 e-141
M26628-1|AAA52294.1| 750|Homo sapiens enkephalinase protein. 503 e-141
BC101658-1|AAI01659.1| 750|Homo sapiens membrane metallo-endope... 503 e-141
BC101632-1|AAI01633.1| 750|Homo sapiens membrane metallo-endope... 503 e-141
Z35307-1|CAA84548.1| 753|Homo sapiens endothelin-converting-enz... 500 e-141
X91923-1|CAA63016.1| 758|Homo sapiens endothelin-converting enz... 500 e-141
X91922-1|CAA63015.1| 770|Homo sapiens endothelin-converting enz... 500 e-141
D49471-1|BAA08442.1| 770|Homo sapiens endothelin converting enz... 500 e-141
D43698-1|BAA07800.1| 758|Homo sapiens endothelin-converting enz... 500 e-141
BC126257-1|AAI26258.1| 770|Homo sapiens endothelin converting e... 500 e-141
BC117256-1|AAI17257.1| 770|Homo sapiens endothelin converting e... 500 e-141
AY953519-1|AAX35820.1| 761|Homo sapiens endothelin converting e... 500 e-141
AL031728-2|CAI19064.1| 754|Homo sapiens endothelin converting e... 500 e-141
AL031728-1|CAB52285.2| 770|Homo sapiens endothelin converting e... 500 e-141
AL031005-4|CAI20195.1| 758|Homo sapiens endothelin converting e... 500 e-141
AL031005-3|CAI20194.1| 754|Homo sapiens endothelin converting e... 500 e-141
AL031005-1|CAI20192.1| 770|Homo sapiens endothelin converting e... 500 e-141
AB031742-1|BAA83687.1| 754|Homo sapiens endothelin-converting e... 500 e-141
J03779-1|AAA51915.1| 750|Homo sapiens MME protein. 500 e-141
Y10196-1|CAA71258.1| 749|Homo sapiens PHEX protein. 487 e-137
Y08111-1|CAA69326.1| 749|Homo sapiens PHEX protein. 487 e-137
U87284-1|AAB47562.1| 749|Homo sapiens phosphate regulating neut... 487 e-137
U75645-1|AAB47749.1| 749|Homo sapiens PEX protein protein. 487 e-137
BC105059-1|AAI05060.1| 749|Homo sapiens X-linked phosphate regu... 487 e-137
BC105057-1|AAI05058.1| 749|Homo sapiens phosphate regulating en... 487 e-137
AD000712-1|AAB51604.1| 749|Homo sapiens PEX protein. 487 e-137
U82970-1|AAC24487.1| 749|Homo sapiens metalloendopeptidase homo... 487 e-137
BC050453-1|AAH50453.2| 775|Homo sapiens endothelin converting e... 446 e-124
AJ130734-1|CAB86601.1| 775|Homo sapiens xce protein. 446 e-124
AC092165-1|AAY24101.1| 775|Homo sapiens unknown protein. 446 e-124
Y16187-1|CAA76113.1| 775|Homo sapiens metallopeptidase protein. 442 e-123
AY358923-1|AAQ89282.1| 775|Homo sapiens ECEL1 protein. 442 e-123
DQ114476-1|AAZ22338.1| 773|Homo sapiens endothelin converting e... 439 e-122
U81183-1|AAB42219.1| 633|Homo sapiens phosphate regulator protein. 388 e-107
U60475-1|AAC50552.1| 638|Homo sapiens metalloendopeptidase homo... 384 e-106
BC101028-1|AAI01029.2| 622|Homo sapiens MMEL1 protein protein. 352 2e-96
BC101029-1|AAI01030.1| 611|Homo sapiens MMEL1 protein protein. 296 2e-79
AM085120-1|CAJ30274.1| 730|Homo sapiens kell blood group antige... 212 5e-54
M64934-1|AAA03192.1| 732|Homo sapiens kell blood group protein ... 211 6e-54
BC050639-1|AAH50639.1| 732|Homo sapiens Kell blood group, metal... 211 6e-54
BC003135-1|AAH03135.1| 732|Homo sapiens Kell blood group, metal... 211 6e-54
AY228336-1|AAO38053.1| 732|Homo sapiens Kell blood group protein. 211 6e-54
AF172627-1|AAB33459.1| 732|Homo sapiens Kell protein protein. 211 6e-54
AM085116-1|CAJ30270.1| 730|Homo sapiens kell blood group antige... 210 1e-53
AM085124-1|CAJ30278.1| 730|Homo sapiens kell blood group antige... 210 2e-53
AM085117-1|CAJ30271.1| 730|Homo sapiens kell blood group antige... 210 2e-53
AM085115-1|CAJ30269.1| 730|Homo sapiens kell blood group antige... 210 2e-53
AM085113-1|CAJ30267.1| 730|Homo sapiens kell blood group antige... 210 2e-53
AM085121-1|CAJ30275.1| 730|Homo sapiens kell blood group antige... 209 2e-53
AM085123-1|CAJ30277.1| 730|Homo sapiens kell blood group antige... 208 4e-53
AM085119-1|CAJ30273.1| 730|Homo sapiens kell blood group antige... 208 7e-53
AM085118-1|CAJ30272.1| 672|Homo sapiens truncated kell blood gr... 176 3e-43
AL031005-2|CAI20193.1| 197|Homo sapiens endothelin converting e... 154 1e-36
AB030579-1|BAC66225.1| 306|Homo sapiens endotheline-converting ... 103 2e-21
AM085114-1|CAJ30268.1| 403|Homo sapiens truncated kell blood gr... 89 5e-17
AM085122-1|CAJ30276.1| 346|Homo sapiens truncated kell blood gr... 85 9e-16
AF018034-1|AAD21221.1| 58|Homo sapiens endothelin converting e... 73 3e-12
U73024-1|AAD08630.1| 116|Homo sapiens phosphate regulating neut... 55 8e-07
AM085127-1|CAJ30281.1| 177|Homo sapiens kell blood group antige... 54 2e-06
AM085128-1|CAJ30282.1| 91|Homo sapiens truncated kell blood gr... 41 0.014
AJ130828-1|CAB46443.1| 129|Homo sapiens human endothelin-conver... 41 0.014
DQ923321-1|ABI96895.1| 84|Homo sapiens kell blood group protei... 38 0.13
AF279657-1|AAK69488.1| 84|Homo sapiens Kell blood group protei... 38 0.13
AM183928-1|CAJ75457.1| 63|Homo sapiens Kell blood group antige... 36 0.71
AJ012371-1|CAB39968.1| 740|Homo sapiens NAALADase L protein pro... 35 1.2
AF010141-1|AAB87645.1| 322|Homo sapiens peptidase homolog protein. 35 1.2
>AF521189-1|AAM77664.1| 811|Homo sapiens endothelin-converting
enzyme-2C protein.
Length = 811
Score = 512 bits (1264), Expect = e-144
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 14/684 (2%)
Query: 81 TCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQ 140
TC CI A ++L ++D V PC++FY F+CG +++ +PD ++ NTF+ + DQ Q
Sbjct: 139 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQ 198
Query: 141 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 200
++ LL+ + Y +C+ IE G QPL D+++++GGW +
Sbjct: 199 AILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITG--P 256
Query: 201 WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNR 258
WD+++F V K Y F IS D K+S VI +DQ+ L L SR+Y LNR
Sbjct: 257 WDQDNF---MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 313
Query: 259 GFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ AY +YM ++ +LLG T E++++ L+ E++LANI++P ++RR+ +Y+
Sbjct: 314 TANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYH 373
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
M+I+ELQ P + WLE+++ LL+P + + +E +V Y+ + L+ +T +
Sbjct: 374 KMSISELQALAPSMDWLEFLSFLLSP-LELSDSEPVVVYGMDYLQQVSELINRTEPSILN 432
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S L Q + L G K RW+ C T ++ A+G+L+
Sbjct: 433 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 492
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F+ SK A M+++IR F + L ++ WMD+ TRQ A EKADA+ I +P +L
Sbjct: 493 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 552
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
+ L + Y G E+S + +++LNL F+ + + +LR+P ++ W P VNA+Y
Sbjct: 553 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSM--TPQTVNAYY 610
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
+N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK GNL W
Sbjct: 611 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 670
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
WQ + + + C+ +QY+ Y V G +LNG T GENIADNGG+K AY AY+AW
Sbjct: 671 WQNESLAAFRNHTACMEEQYNQYQVN--GERLNGRQTLGENIADNGGLKAAYNAYKAWLR 728
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
+HGEE +LP + + QLF++ A WC+V E+ + T H+P RFRV+G +SN
Sbjct: 729 KHGEEQQLPAV-GLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNS 787
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+F F CP+GSPMNP + C+VW
Sbjct: 788 RDFLRHFGCPVGSPMNPGQLCEVW 811
>AF428264-1|AAL30387.1| 736|Homo sapiens endothelin converting
enzyme-2B protein.
Length = 736
Score = 512 bits (1264), Expect = e-144
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 14/684 (2%)
Query: 81 TCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQ 140
TC CI A ++L ++D V PC++FY F+CG +++ +PD ++ NTF+ + DQ Q
Sbjct: 64 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQ 123
Query: 141 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 200
++ LL+ + Y +C+ IE G QPL D+++++GGW +
Sbjct: 124 AILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITG--P 181
Query: 201 WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNR 258
WD+++F V K Y F IS D K+S VI +DQ+ L L SR+Y LNR
Sbjct: 182 WDQDNF---MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 238
Query: 259 GFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ AY +YM ++ +LLG T E++++ L+ E++LANI++P ++RR+ +Y+
Sbjct: 239 TANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYH 298
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
M+I+ELQ P + WLE+++ LL+P + + +E +V Y+ + L+ +T +
Sbjct: 299 KMSISELQALAPSMDWLEFLSFLLSP-LELSDSEPVVVYGMDYLQQVSELINRTEPSILN 357
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S L Q + L G K RW+ C T ++ A+G+L+
Sbjct: 358 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 417
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F+ SK A M+++IR F + L ++ WMD+ TRQ A EKADA+ I +P +L
Sbjct: 418 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 477
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
+ L + Y G E+S + +++LNL F+ + + +LR+P ++ W P VNA+Y
Sbjct: 478 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSM--TPQTVNAYY 535
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
+N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK GNL W
Sbjct: 536 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 595
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
WQ + + + C+ +QY+ Y V G +LNG T GENIADNGG+K AY AY+AW
Sbjct: 596 WQNESLAAFRNHTACMEEQYNQYQVN--GERLNGRQTLGENIADNGGLKAAYNAYKAWLR 653
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
+HGEE +LP + + QLF++ A WC+V E+ + T H+P RFRV+G +SN
Sbjct: 654 KHGEEQQLPAV-GLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNS 712
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+F F CP+GSPMNP + C+VW
Sbjct: 713 RDFLRHFGCPVGSPMNPGQLCEVW 736
>AF428263-1|AAL30386.1| 787|Homo sapiens endothelin converting
enzyme-2A protein.
Length = 787
Score = 512 bits (1264), Expect = e-144
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 14/684 (2%)
Query: 81 TCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQ 140
TC CI A ++L ++D V PC++FY F+CG +++ +PD ++ NTF+ + DQ Q
Sbjct: 115 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQ 174
Query: 141 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 200
++ LL+ + Y +C+ IE G QPL D+++++GGW +
Sbjct: 175 AILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITG--P 232
Query: 201 WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNR 258
WD+++F V K Y F IS D K+S VI +DQ+ L L SR+Y LNR
Sbjct: 233 WDQDNF---MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 289
Query: 259 GFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ AY +YM ++ +LLG T E++++ L+ E++LANI++P ++RR+ +Y+
Sbjct: 290 TANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYH 349
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
M+I+ELQ P + WLE+++ LL+P + + +E +V Y+ + L+ +T +
Sbjct: 350 KMSISELQALAPSMDWLEFLSFLLSP-LELSDSEPVVVYGMDYLQQVSELINRTEPSILN 408
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S L Q + L G K RW+ C T ++ A+G+L+
Sbjct: 409 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 468
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F+ SK A M+++IR F + L ++ WMD+ TRQ A EKADA+ I +P +L
Sbjct: 469 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 528
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
+ L + Y G E+S + +++LNL F+ + + +LR+P ++ W P VNA+Y
Sbjct: 529 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSM--TPQTVNAYY 586
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
+N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK GNL W
Sbjct: 587 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 646
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
WQ + + + C+ +QY+ Y V G +LNG T GENIADNGG+K AY AY+AW
Sbjct: 647 WQNESLAAFRNHTACMEEQYNQYQVN--GERLNGRQTLGENIADNGGLKAAYNAYKAWLR 704
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
+HGEE +LP + + QLF++ A WC+V E+ + T H+P RFRV+G +SN
Sbjct: 705 KHGEEQQLPAV-GLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNS 763
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+F F CP+GSPMNP + C+VW
Sbjct: 764 RDFLRHFGCPVGSPMNPGQLCEVW 787
>AF192531-1|AAG28399.1| 765|Homo sapiens endothelin-converting
enzyme 2B protein.
Length = 765
Score = 512 bits (1264), Expect = e-144
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 14/684 (2%)
Query: 81 TCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQ 140
TC CI A ++L ++D V PC++FY F+CG +++ +PD ++ NTF+ + DQ Q
Sbjct: 93 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQ 152
Query: 141 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 200
++ LL+ + Y +C+ IE G QPL D+++++GGW +
Sbjct: 153 AILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITG--P 210
Query: 201 WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNR 258
WD+++F V K Y F IS D K+S VI +DQ+ L L SR+Y LNR
Sbjct: 211 WDQDNF---MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 267
Query: 259 GFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ AY +YM ++ +LLG T E++++ L+ E++LANI++P ++RR+ +Y+
Sbjct: 268 TANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYH 327
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
M+I+ELQ P + WLE+++ LL+P + + +E +V Y+ + L+ +T +
Sbjct: 328 KMSISELQALAPSMDWLEFLSFLLSP-LELSDSEPVVVYGMDYLQQVSELINRTEPSILN 386
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S L Q + L G K RW+ C T ++ A+G+L+
Sbjct: 387 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 446
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F+ SK A M+++IR F + L ++ WMD+ TRQ A EKADA+ I +P +L
Sbjct: 447 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 506
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
+ L + Y G E+S + +++LNL F+ + + +LR+P ++ W P VNA+Y
Sbjct: 507 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSM--TPQTVNAYY 564
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
+N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK GNL W
Sbjct: 565 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 624
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
WQ + + + C+ +QY+ Y V G +LNG T GENIADNGG+K AY AY+AW
Sbjct: 625 WQNESLAAFRNHTACMEEQYNQYQVN--GERLNGRQTLGENIADNGGLKAAYNAYKAWLR 682
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
+HGEE +LP + + QLF++ A WC+V E+ + T H+P RFRV+G +SN
Sbjct: 683 KHGEEQQLPAV-GLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNS 741
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+F F CP+GSPMNP + C+VW
Sbjct: 742 RDFLRHFGCPVGSPMNPGQLCEVW 765
>AB011176-1|BAA25530.2| 773|Homo sapiens KIAA0604 protein protein.
Length = 773
Score = 512 bits (1264), Expect = e-144
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 14/684 (2%)
Query: 81 TCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQ 140
TC CI A ++L ++D V PC++FY F+CG +++ +PD ++ NTF+ + DQ Q
Sbjct: 101 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQ 160
Query: 141 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 200
++ LL+ + Y +C+ IE G QPL D+++++GGW +
Sbjct: 161 AILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITG--P 218
Query: 201 WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNR 258
WD+++F V K Y F IS D K+S VI +DQ+ L L SR+Y LNR
Sbjct: 219 WDQDNF---MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 275
Query: 259 GFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ AY +YM ++ +LLG T E++++ L+ E++LANI++P ++RR+ +Y+
Sbjct: 276 TANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYH 335
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
M+I+ELQ P + WLE+++ LL+P + + +E +V Y+ + L+ +T +
Sbjct: 336 KMSISELQALAPSMDWLEFLSFLLSP-LELSDSEPVVVYGMDYLQQVSELINRTEPSILN 394
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S L Q + L G K RW+ C T ++ A+G+L+
Sbjct: 395 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 454
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F+ SK A M+++IR F + L ++ WMD+ TRQ A EKADA+ I +P +L
Sbjct: 455 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 514
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
+ L + Y G E+S + +++LNL F+ + + +LR+P ++ W P VNA+Y
Sbjct: 515 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSM--TPQTVNAYY 572
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
+N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK GNL W
Sbjct: 573 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 632
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
WQ + + + C+ +QY+ Y V G +LNG T GENIADNGG+K AY AY+AW
Sbjct: 633 WQNESLAAFRNHTACMEEQYNQYQVN--GERLNGRQTLGENIADNGGLKAAYNAYKAWLR 690
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
+HGEE +LP + + QLF++ A WC+V E+ + T H+P RFRV+G +SN
Sbjct: 691 KHGEEQQLPAV-GLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNS 749
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+F F CP+GSPMNP + C+VW
Sbjct: 750 RDFLRHFGCPVGSPMNPGQLCEVW 773
>AY359003-1|AAQ89362.1| 736|Homo sapiens ECE2 protein.
Length = 736
Score = 511 bits (1260), Expect = e-144
Identities = 253/684 (36%), Positives = 398/684 (58%), Gaps = 14/684 (2%)
Query: 81 TCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQ 140
TC CI A ++L ++D V PC++FY F+CG +++ +PD ++ NTF+ + DQ Q
Sbjct: 64 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQ 123
Query: 141 EQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQS 200
++ LL+ + Y +C+ IE G QPL D+++++GGW +
Sbjct: 124 AILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITG--P 181
Query: 201 WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNR 258
WD+++F V K Y F IS D K+S VI +DQ+ L L SR+Y LNR
Sbjct: 182 WDQDNF---MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 238
Query: 259 GFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ AY +YM ++ +LLG T E++++ L+ E++LANI++P ++RR+ +Y+
Sbjct: 239 TANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYH 298
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
M+I+ELQ P + WLE+++ LL+P + + +E +V Y+ + L+ +T +
Sbjct: 299 KMSISELQALAPSMDWLEFLSFLLSP-LELSDSEPVVVYGMDYLQQVSELINRTEPSILN 357
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S L Q + L G K RW+ C T ++ A+G+L+
Sbjct: 358 NYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLF 417
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F+ SK A M+++IR F + L ++ WMD+ TRQ A EKADA+ I +P +L
Sbjct: 418 VKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 477
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
+ L + Y G E+S + +++LNL F+ + + +LR+P ++ W P VNA+Y
Sbjct: 478 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSM--TPQTVNAYY 535
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
+N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK GNL W
Sbjct: 536 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 595
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
WQ + + + C+ +QY+ Y V G +LNG T GENI DNGG+K AY AY+AW
Sbjct: 596 WQNESLAAFRNHTACMEEQYNQYQVN--GERLNGRQTLGENITDNGGLKAAYNAYKAWLR 653
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
+HGEE +LP + + QLF++ A WC+V E+ + T H+P RFRV+G +SN
Sbjct: 654 KHGEEQQLPAV-GLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNS 712
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+F F CP+GSPMNP + C+VW
Sbjct: 713 RDFLRHFGCPVGSPMNPGQLCEVW 736
>BC101027-1|AAI01028.2| 770|Homo sapiens membrane
metallo-endopeptidase-like 1 protein.
Length = 770
Score = 510 bits (1259), Expect = e-144
Identities = 265/709 (37%), Positives = 418/709 (58%), Gaps = 21/709 (2%)
Query: 69 PAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTS 128
P + + E C+ PGC+ A+R+L NMD +PCD+FY FACG +L+ IP+ +
Sbjct: 67 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 126
Query: 129 VNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLK 188
+ F ++ D+L+ ++++L+ + P A+TLY++CMN++ IE RG QPLLD+L+
Sbjct: 127 YSIFDVLRDELEVILKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILE 185
Query: 189 RLGGWPVLDGQSWDEN-SFSWE-QSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQ 246
+GGWPV + W+E WE + ++ ++ +D I D +NS+R +I +DQ
Sbjct: 186 VVGGWPVAMDR-WNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 244
Query: 247 ASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK------ATEELKESLQFEM 298
+LG+ SREY N G + K+ +AY ++MV +A LL D E++ + L+ E
Sbjct: 245 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 304
Query: 299 KLANISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP-HITVDVNELTI 355
+LA ++P E+R + +LY+ M + ELQ +F W +I +L+ I + +E +
Sbjct: 305 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 364
Query: 356 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 415
V Y+ +LE +++ R NY++WR+ + L+ + ++ Y AL G E
Sbjct: 365 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 424
Query: 416 SRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMT 475
RW+EC +++M AVG+LY+R+ F +SK+ E+++ +R F +TL ++ WMD+ +
Sbjct: 425 VRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEES 484
Query: 476 RQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFG 533
+++A EKA ++ I +P +L+ N RL E YS L S + E+ L +
Sbjct: 485 KKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLR 544
Query: 534 KLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVI 593
KLRE V+ W+ A+VNAFYS N I FPAGILQ FFS ++P +N+G IG VI
Sbjct: 545 KLREKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVI 602
Query: 594 GHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVG-LKLNGV 652
GHEITHGFDD GR FDKNGN++DWW + + + ++++C+I QY NY+ +NG
Sbjct: 603 GHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGF 662
Query: 653 NTQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNE 712
NT GENIADNGG+++AY AY W G++ +LPGL+ + QLF+++ A WC YR E
Sbjct: 663 NTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLD-LTHEQLFFINYAQVWCGSYRPE 721
Query: 713 AIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
I T H+P ++RV+G + N+ FA F C G+PM+P ++C+VW
Sbjct: 722 FAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 770
>AL831784-1|CAI17336.1| 779|Homo sapiens mel transforming
oncogene-like 1 protein.
Length = 779
Score = 510 bits (1259), Expect = e-144
Identities = 265/709 (37%), Positives = 418/709 (58%), Gaps = 21/709 (2%)
Query: 69 PAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTS 128
P + + E C+ PGC+ A+R+L NMD +PCD+FY FACG +L+ IP+ +
Sbjct: 76 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 135
Query: 129 VNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLK 188
+ F ++ D+L+ ++++L+ + P A+TLY++CMN++ IE RG QPLLD+L+
Sbjct: 136 YSIFDVLRDELEVILKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILE 194
Query: 189 RLGGWPVLDGQSWDEN-SFSWE-QSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQ 246
+GGWPV + W+E WE + ++ ++ +D I D +NS+R +I +DQ
Sbjct: 195 VVGGWPVAMDR-WNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 253
Query: 247 ASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK------ATEELKESLQFEM 298
+LG+ SREY N G + K+ +AY ++MV +A LL D E++ + L+ E
Sbjct: 254 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
Query: 299 KLANISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP-HITVDVNELTI 355
+LA ++P E+R + +LY+ M + ELQ +F W +I +L+ I + +E +
Sbjct: 314 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 373
Query: 356 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 415
V Y+ +LE +++ R NY++WR+ + L+ + ++ Y AL G E
Sbjct: 374 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 433
Query: 416 SRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMT 475
RW+EC +++M AVG+LY+R+ F +SK+ E+++ +R F +TL ++ WMD+ +
Sbjct: 434 VRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEES 493
Query: 476 RQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFG 533
+++A EKA ++ I +P +L+ N RL E YS L S + E+ L +
Sbjct: 494 KKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLR 553
Query: 534 KLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVI 593
KLRE V+ W+ A+VNAFYS N I FPAGILQ FFS ++P +N+G IG VI
Sbjct: 554 KLREKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVI 611
Query: 594 GHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVG-LKLNGV 652
GHEITHGFDD GR FDKNGN++DWW + + + ++++C+I QY NY+ +NG
Sbjct: 612 GHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGF 671
Query: 653 NTQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNE 712
NT GENIADNGG+++AY AY W G++ +LPGL+ + QLF+++ A WC YR E
Sbjct: 672 NTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLD-LTHEQLFFINYAQVWCGSYRPE 730
Query: 713 AIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
I T H+P ++RV+G + N+ FA F C G+PM+P ++C+VW
Sbjct: 731 FAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
>AL589746-1|CAI22652.1| 779|Homo sapiens mel transforming
oncogene-like 1 protein.
Length = 779
Score = 510 bits (1259), Expect = e-144
Identities = 265/709 (37%), Positives = 418/709 (58%), Gaps = 21/709 (2%)
Query: 69 PAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTS 128
P + + E C+ PGC+ A+R+L NMD +PCD+FY FACG +L+ IP+ +
Sbjct: 76 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 135
Query: 129 VNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLK 188
+ F ++ D+L+ ++++L+ + P A+TLY++CMN++ IE RG QPLLD+L+
Sbjct: 136 YSIFDVLRDELEVILKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILE 194
Query: 189 RLGGWPVLDGQSWDEN-SFSWE-QSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQ 246
+GGWPV + W+E WE + ++ ++ +D I D +NS+R +I +DQ
Sbjct: 195 VVGGWPVAMDR-WNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 253
Query: 247 ASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK------ATEELKESLQFEM 298
+LG+ SREY N G + K+ +AY ++MV +A LL D E++ + L+ E
Sbjct: 254 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
Query: 299 KLANISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP-HITVDVNELTI 355
+LA ++P E+R + +LY+ M + ELQ +F W +I +L+ I + +E +
Sbjct: 314 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 373
Query: 356 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 415
V Y+ +LE +++ R NY++WR+ + L+ + ++ Y AL G E
Sbjct: 374 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 433
Query: 416 SRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMT 475
RW+EC +++M AVG+LY+R+ F +SK+ E+++ +R F +TL ++ WMD+ +
Sbjct: 434 VRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEES 493
Query: 476 RQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFG 533
+++A EKA ++ I +P +L+ N RL E YS L S + E+ L +
Sbjct: 494 KKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLR 553
Query: 534 KLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVI 593
KLRE V+ W+ A+VNAFYS N I FPAGILQ FFS ++P +N+G IG VI
Sbjct: 554 KLREKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVI 611
Query: 594 GHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVG-LKLNGV 652
GHEITHGFDD GR FDKNGN++DWW + + + ++++C+I QY NY+ +NG
Sbjct: 612 GHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGF 671
Query: 653 NTQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNE 712
NT GENIADNGG+++AY AY W G++ +LPGL+ + QLF+++ A WC YR E
Sbjct: 672 NTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLD-LTHEQLFFINYAQVWCGSYRPE 730
Query: 713 AIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
I T H+P ++RV+G + N+ FA F C G+PM+P ++C+VW
Sbjct: 731 FAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
>AF336981-1|AAL08942.1| 770|Homo sapiens neprilysin-like
metallopeptidase 2 protein.
Length = 770
Score = 510 bits (1259), Expect = e-144
Identities = 265/709 (37%), Positives = 418/709 (58%), Gaps = 21/709 (2%)
Query: 69 PAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTS 128
P + + E C+ PGC+ A+R+L NMD +PCD+FY FACG +L+ IP+ +
Sbjct: 67 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 126
Query: 129 VNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLK 188
+ F ++ D+L+ ++++L+ + P A+TLY++CMN++ IE RG QPLLD+L+
Sbjct: 127 YSIFDVLRDELEVILKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILE 185
Query: 189 RLGGWPVLDGQSWDEN-SFSWE-QSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQ 246
+GGWPV + W+E WE + ++ ++ +D I D +NS+R +I +DQ
Sbjct: 186 VVGGWPVAMDR-WNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 244
Query: 247 ASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK------ATEELKESLQFEM 298
+LG+ SREY N G + K+ +AY ++MV +A LL D E++ + L+ E
Sbjct: 245 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 304
Query: 299 KLANISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP-HITVDVNELTI 355
+LA ++P E+R + +LY+ M + ELQ +F W +I +L+ I + +E +
Sbjct: 305 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 364
Query: 356 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 415
V Y+ +LE +++ R NY++WR+ + L+ + ++ Y AL G E
Sbjct: 365 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 424
Query: 416 SRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMT 475
RW+EC +++M AVG+LY+R+ F +SK+ E+++ +R F +TL ++ WMD+ +
Sbjct: 425 VRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEES 484
Query: 476 RQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFG 533
+++A EKA ++ I +P +L+ N RL E YS L S + E+ L +
Sbjct: 485 KKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLR 544
Query: 534 KLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVI 593
KLRE V+ W+ A+VNAFYS N I FPAGILQ FFS ++P +N+G IG VI
Sbjct: 545 KLREKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVI 602
Query: 594 GHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVG-LKLNGV 652
GHEITHGFDD GR FDKNGN++DWW + + + ++++C+I QY NY+ +NG
Sbjct: 603 GHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGF 662
Query: 653 NTQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNE 712
NT GENIADNGG+++AY AY W G++ +LPGL+ + QLF+++ A WC YR E
Sbjct: 663 NTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLD-LTHEQLFFINYAQVWCGSYRPE 721
Query: 713 AIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
I T H+P ++RV+G + N+ FA F C G+PM+P ++C+VW
Sbjct: 722 FAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 770
>BC101030-1|AAI01031.2| 770|Homo sapiens membrane
metallo-endopeptidase-like 1 protein.
Length = 770
Score = 509 bits (1255), Expect = e-143
Identities = 264/709 (37%), Positives = 418/709 (58%), Gaps = 21/709 (2%)
Query: 69 PAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTS 128
P + + E C+ PGC+ A+R+L NMD +PCD+FY FACG +L+ IP+ +
Sbjct: 67 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 126
Query: 129 VNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLK 188
+ F ++ D+L+ ++++L+ + P A+TLY++CMN++ IE RG QPLLD+L+
Sbjct: 127 YSIFDVLRDELEVILKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILE 185
Query: 189 RLGGWPVLDGQSWDEN-SFSWE-QSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQ 246
+GGWPV + W+E WE + ++ ++ +D I D +NS+R +I +DQ
Sbjct: 186 VVGGWPVAMDR-WNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 244
Query: 247 ASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK------ATEELKESLQFEM 298
+LG+ SREY N G + K+ +AY ++MV +A LL D E++ + L+ E
Sbjct: 245 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 304
Query: 299 KLANISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP-HITVDVNELTI 355
+LA ++P E+R + +LY+ M + ELQ +F W +I +L+ I + +E +
Sbjct: 305 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 364
Query: 356 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 415
V Y+ +LE +++ R NY++WR+ + L+ + ++ Y AL G E
Sbjct: 365 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 424
Query: 416 SRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMT 475
RW+EC +++M AVG+LY+R+ F +SK+ E+++ +R F +TL ++ W+D+ +
Sbjct: 425 VRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWIDEES 484
Query: 476 RQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFG 533
+++A EKA ++ I +P +L+ N RL E YS L S + E+ L +
Sbjct: 485 KKKAQEKAMSIREQIGHPDYILEETNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLR 544
Query: 534 KLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVI 593
KLRE V+ W+ A+VNAFYS N I FPAGILQ FFS ++P +N+G IG VI
Sbjct: 545 KLREKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVI 602
Query: 594 GHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVG-LKLNGV 652
GHEITHGFDD GR FDKNGN++DWW + + + ++++C+I QY NY+ +NG
Sbjct: 603 GHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGF 662
Query: 653 NTQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNE 712
NT GENIADNGG+++AY AY W G++ +LPGL+ + QLF+++ A WC YR E
Sbjct: 663 NTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLD-LTHEQLFFINYAQVWCGSYRPE 721
Query: 713 AIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
I T H+P ++RV+G + N+ FA F C G+PM+P ++C+VW
Sbjct: 722 FAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 770
>Y00811-1|CAA68752.1| 750|Homo sapiens protein ( Human mRNA for
common acute lymphocytic leukemia antigen CALLA (EC
3.4.24.11). ).
Length = 750
Score = 503 bits (1240), Expect = e-141
Identities = 266/700 (38%), Positives = 406/700 (58%), Gaps = 26/700 (3%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + CI +A+RL+ NMD +PC +F+ +ACG +LK IP+ + F I+ D+L+
Sbjct: 57 CKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEV 116
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++ +L EP T E+ AK LY++C+N +AI++RG +PLL +L + GWPV ++W
Sbjct: 117 VLKDVLQEPKT-EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVAT-ENW 174
Query: 202 DEN-SFSW--EQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREYLN 257
++ SW E+++ + ++ Y ++ + D KNS VI +DQ LGL SR+Y
Sbjct: 175 EQKYGASWTAEKAIAQL-NSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYE 233
Query: 258 -RGFSDKLVQAYYEYMVDIAIL------LGADKTKATEELKESLQFEMKLANISLPLEKR 310
G + AY ++M+ +A L L D+ + E+ + ++ E ++AN + E R
Sbjct: 234 CTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDR 293
Query: 311 RNATSLYNPMTIAELQQKFP------KVPWLEYINRLLAP-HITVDVNELTIVSVPKYIT 363
+ LYN MT+A++Q F WL + N +++ +I++ E +V P+Y+T
Sbjct: 294 NDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLT 353
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
L+ +L K R N + WR VS L+ + + A+ AL G T + W+ CA+
Sbjct: 354 KLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCAN 413
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +M AVG LY+ F SK +++ IR+ F +TL + WMD T++ A EKA
Sbjct: 414 YVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKA 473
Query: 484 DAMASHIAYPSEMLDN-NRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKT 542
A+ I YP +++ N N+L Y L + E+++ F+ KLRE V+K
Sbjct: 474 LAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKD 533
Query: 543 DWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 602
+W++ A+VNAFYSS N I FPAGILQ FFSA++ +NYG IG VIGHEITHGFD
Sbjct: 534 EWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFD 591
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEV-GLKLNGVNTQGENIAD 661
D GR F+K+G+LVDWW + + + ++++C++ QY N++ G LNG+NT GENIAD
Sbjct: 592 DNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD 651
Query: 662 NGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
NGG+ +AY AYQ + ++GEE LPGL+ + +QLF+L+ A WC YR E I T
Sbjct: 652 NGGLGQAYRAYQNYIKKNGEEKLLPGLD-LNHKQLFFLNFAQVWCGTYRPEYAVNSIKTD 710
Query: 722 FHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
H+PG FR+IG + N EF+ F C S MNP+KKC+VW
Sbjct: 711 VHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>X07166-1|CAA30157.1| 743|Homo sapiens protein ( Human mRNA for
enkephalinase (EC 3.4.24.11). ).
Length = 743
Score = 503 bits (1240), Expect = e-141
Identities = 266/700 (38%), Positives = 406/700 (58%), Gaps = 26/700 (3%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + CI +A+RL+ NMD +PC +F+ +ACG +LK IP+ + F I+ D+L+
Sbjct: 50 CKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEV 109
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++ +L EP T E+ AK LY++C+N +AI++RG +PLL +L + GWPV ++W
Sbjct: 110 VLKDVLQEPKT-EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVAT-ENW 167
Query: 202 DEN-SFSW--EQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREYLN 257
++ SW E+++ + ++ Y ++ + D KNS VI +DQ LGL SR+Y
Sbjct: 168 EQKYGASWTAEKAIAQL-NSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYE 226
Query: 258 -RGFSDKLVQAYYEYMVDIAIL------LGADKTKATEELKESLQFEMKLANISLPLEKR 310
G + AY ++M+ +A L L D+ + E+ + ++ E ++AN + E R
Sbjct: 227 CTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDR 286
Query: 311 RNATSLYNPMTIAELQQKFP------KVPWLEYINRLLAP-HITVDVNELTIVSVPKYIT 363
+ LYN MT+A++Q F WL + N +++ +I++ E +V P+Y+T
Sbjct: 287 NDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLT 346
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
L+ +L K R N + WR VS L+ + + A+ AL G T + W+ CA+
Sbjct: 347 KLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCAN 406
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +M AVG LY+ F SK +++ IR+ F +TL + WMD T++ A EKA
Sbjct: 407 YVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKA 466
Query: 484 DAMASHIAYPSEMLDN-NRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKT 542
A+ I YP +++ N N+L Y L + E+++ F+ KLRE V+K
Sbjct: 467 LAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKD 526
Query: 543 DWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 602
+W++ A+VNAFYSS N I FPAGILQ FFSA++ +NYG IG VIGHEITHGFD
Sbjct: 527 EWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFD 584
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEV-GLKLNGVNTQGENIAD 661
D GR F+K+G+LVDWW + + + ++++C++ QY N++ G LNG+NT GENIAD
Sbjct: 585 DNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD 644
Query: 662 NGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
NGG+ +AY AYQ + ++GEE LPGL+ + +QLF+L+ A WC YR E I T
Sbjct: 645 NGGLGQAYRAYQNYIKKNGEEKLLPGLD-LNHKQLFFLNFAQVWCGTYRPEYAVNSIKTD 703
Query: 722 FHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
H+PG FR+IG + N EF+ F C S MNP+KKC+VW
Sbjct: 704 VHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 743
>M26628-1|AAA52294.1| 750|Homo sapiens enkephalinase protein.
Length = 750
Score = 503 bits (1240), Expect = e-141
Identities = 266/700 (38%), Positives = 406/700 (58%), Gaps = 26/700 (3%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + CI +A+RL+ NMD +PC +F+ +ACG +LK IP+ + F I+ D+L+
Sbjct: 57 CKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEV 116
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++ +L EP T E+ AK LY++C+N +AI++RG +PLL +L + GWPV ++W
Sbjct: 117 VLKDVLQEPKT-EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVAT-ENW 174
Query: 202 DEN-SFSW--EQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREYLN 257
++ SW E+++ + ++ Y ++ + D KNS VI +DQ LGL SR+Y
Sbjct: 175 EQKYGASWTAEKAIAQL-NSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYE 233
Query: 258 -RGFSDKLVQAYYEYMVDIAIL------LGADKTKATEELKESLQFEMKLANISLPLEKR 310
G + AY ++M+ +A L L D+ + E+ + ++ E ++AN + E R
Sbjct: 234 CTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDR 293
Query: 311 RNATSLYNPMTIAELQQKFP------KVPWLEYINRLLAP-HITVDVNELTIVSVPKYIT 363
+ LYN MT+A++Q F WL + N +++ +I++ E +V P+Y+T
Sbjct: 294 NDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLT 353
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
L+ +L K R N + WR VS L+ + + A+ AL G T + W+ CA+
Sbjct: 354 KLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCAN 413
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +M AVG LY+ F SK +++ IR+ F +TL + WMD T++ A EKA
Sbjct: 414 YVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKA 473
Query: 484 DAMASHIAYPSEMLDN-NRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKT 542
A+ I YP +++ N N+L Y L + E+++ F+ KLRE V+K
Sbjct: 474 LAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKD 533
Query: 543 DWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 602
+W++ A+VNAFYSS N I FPAGILQ FFSA++ +NYG IG VIGHEITHGFD
Sbjct: 534 EWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFD 591
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEV-GLKLNGVNTQGENIAD 661
D GR F+K+G+LVDWW + + + ++++C++ QY N++ G LNG+NT GENIAD
Sbjct: 592 DNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD 651
Query: 662 NGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
NGG+ +AY AYQ + ++GEE LPGL+ + +QLF+L+ A WC YR E I T
Sbjct: 652 NGGLGQAYRAYQNYIKKNGEEKLLPGLD-LNHKQLFFLNFAQVWCGTYRPEYAVNSIKTD 710
Query: 722 FHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
H+PG FR+IG + N EF+ F C S MNP+KKC+VW
Sbjct: 711 VHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>BC101658-1|AAI01659.1| 750|Homo sapiens membrane
metallo-endopeptidase protein.
Length = 750
Score = 503 bits (1240), Expect = e-141
Identities = 266/700 (38%), Positives = 406/700 (58%), Gaps = 26/700 (3%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + CI +A+RL+ NMD +PC +F+ +ACG +LK IP+ + F I+ D+L+
Sbjct: 57 CKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEV 116
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++ +L EP T E+ AK LY++C+N +AI++RG +PLL +L + GWPV ++W
Sbjct: 117 VLKDVLQEPKT-EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVAT-ENW 174
Query: 202 DEN-SFSW--EQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREYLN 257
++ SW E+++ + ++ Y ++ + D KNS VI +DQ LGL SR+Y
Sbjct: 175 EQKYGASWTAEKAIAQL-NSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYE 233
Query: 258 -RGFSDKLVQAYYEYMVDIAIL------LGADKTKATEELKESLQFEMKLANISLPLEKR 310
G + AY ++M+ +A L L D+ + E+ + ++ E ++AN + E R
Sbjct: 234 CTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDR 293
Query: 311 RNATSLYNPMTIAELQQKFP------KVPWLEYINRLLAP-HITVDVNELTIVSVPKYIT 363
+ LYN MT+A++Q F WL + N +++ +I++ E +V P+Y+T
Sbjct: 294 NDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLT 353
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
L+ +L K R N + WR VS L+ + + A+ AL G T + W+ CA+
Sbjct: 354 KLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCAN 413
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +M AVG LY+ F SK +++ IR+ F +TL + WMD T++ A EKA
Sbjct: 414 YVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKA 473
Query: 484 DAMASHIAYPSEMLDN-NRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKT 542
A+ I YP +++ N N+L Y L + E+++ F+ KLRE V+K
Sbjct: 474 LAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKD 533
Query: 543 DWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 602
+W++ A+VNAFYSS N I FPAGILQ FFSA++ +NYG IG VIGHEITHGFD
Sbjct: 534 EWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFD 591
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEV-GLKLNGVNTQGENIAD 661
D GR F+K+G+LVDWW + + + ++++C++ QY N++ G LNG+NT GENIAD
Sbjct: 592 DNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD 651
Query: 662 NGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
NGG+ +AY AYQ + ++GEE LPGL+ + +QLF+L+ A WC YR E I T
Sbjct: 652 NGGLGQAYRAYQNYIKKNGEEKLLPGLD-LNHKQLFFLNFAQVWCGTYRPEYAVNSIKTD 710
Query: 722 FHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
H+PG FR+IG + N EF+ F C S MNP+KKC+VW
Sbjct: 711 VHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>BC101632-1|AAI01633.1| 750|Homo sapiens membrane
metallo-endopeptidase protein.
Length = 750
Score = 503 bits (1240), Expect = e-141
Identities = 266/700 (38%), Positives = 406/700 (58%), Gaps = 26/700 (3%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + CI +A+RL+ NMD +PC +F+ +ACG +LK IP+ + F I+ D+L+
Sbjct: 57 CKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEV 116
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++ +L EP T E+ AK LY++C+N +AI++RG +PLL +L + GWPV ++W
Sbjct: 117 VLKDVLQEPKT-EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVAT-ENW 174
Query: 202 DEN-SFSW--EQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREYLN 257
++ SW E+++ + ++ Y ++ + D KNS VI +DQ LGL SR+Y
Sbjct: 175 EQKYGASWTAEKAIAQL-NSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYE 233
Query: 258 -RGFSDKLVQAYYEYMVDIAIL------LGADKTKATEELKESLQFEMKLANISLPLEKR 310
G + AY ++M+ +A L L D+ + E+ + ++ E ++AN + E R
Sbjct: 234 CTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDR 293
Query: 311 RNATSLYNPMTIAELQQKFP------KVPWLEYINRLLAP-HITVDVNELTIVSVPKYIT 363
+ LYN MT+A++Q F WL + N +++ +I++ E +V P+Y+T
Sbjct: 294 NDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLT 353
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
L+ +L K R N + WR VS L+ + + A+ AL G T + W+ CA+
Sbjct: 354 KLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCAN 413
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +M AVG LY+ F SK +++ IR+ F +TL + WMD T++ A EKA
Sbjct: 414 YVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKA 473
Query: 484 DAMASHIAYPSEMLDN-NRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKT 542
A+ I YP +++ N N+L Y L + E+++ F+ KLRE V+K
Sbjct: 474 LAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKD 533
Query: 543 DWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 602
+W++ A+VNAFYSS N I FPAGILQ FFSA++ +NYG IG VIGHEITHGFD
Sbjct: 534 EWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFD 591
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEV-GLKLNGVNTQGENIAD 661
D GR F+K+G+LVDWW + + + ++++C++ QY N++ G LNG+NT GENIAD
Sbjct: 592 DNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD 651
Query: 662 NGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
NGG+ +AY AYQ + ++GEE LPGL+ + +QLF+L+ A WC YR E I T
Sbjct: 652 NGGLGQAYRAYQNYIKKNGEEKLLPGLD-LNHKQLFFLNFAQVWCGTYRPEYAVNSIKTD 710
Query: 722 FHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
H+PG FR+IG + N EF+ F C S MNP+KKC+VW
Sbjct: 711 VHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>Z35307-1|CAA84548.1| 753|Homo sapiens endothelin-converting-enzyme
1 protein.
Length = 753
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 82 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 141
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 142 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 198
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 199 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 255
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 256 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 315
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 316 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 374
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 375 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 434
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 435 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 494
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 495 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 552
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 553 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 612
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 613 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 670
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 671 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 729
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 730 KEFSEHFRCPPGSPMNPPHKCEVW 753
>X91923-1|CAA63016.1| 758|Homo sapiens endothelin-converting
enzyme, isoform ECE-1a protein.
Length = 758
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 87 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 146
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 147 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 203
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 204 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 260
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 261 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 320
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 321 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 379
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 380 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 439
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 440 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 499
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 500 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 557
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 558 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 617
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 618 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 675
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 676 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 734
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 735 KEFSEHFRCPPGSPMNPPHKCEVW 758
>X91922-1|CAA63015.1| 770|Homo sapiens endothelin-converting
enzyme, isoform ECE-1b protein.
Length = 770
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 99 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 158
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 159 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 215
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 216 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 272
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 273 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 332
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 333 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 391
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 392 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 451
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 452 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 511
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 512 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 569
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 570 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 629
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 630 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 687
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 688 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 746
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 747 KEFSEHFRCPPGSPMNPPHKCEVW 770
>D49471-1|BAA08442.1| 770|Homo sapiens endothelin converting enzyme
protein.
Length = 770
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 99 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 158
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 159 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 215
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 216 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 272
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 273 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 332
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 333 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 391
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 392 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 451
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 452 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 511
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 512 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 569
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 570 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 629
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 630 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 687
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 688 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 746
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 747 KEFSEHFRCPPGSPMNPPHKCEVW 770
>D43698-1|BAA07800.1| 758|Homo sapiens endothelin-converting enzyme
protein.
Length = 758
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 87 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 146
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 147 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 203
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 204 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 260
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 261 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 320
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 321 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 379
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 380 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 439
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 440 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 499
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 500 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 557
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 558 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 617
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 618 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 675
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 676 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 734
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 735 KEFSEHFRCPPGSPMNPPHKCEVW 758
>BC126257-1|AAI26258.1| 770|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 770
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 99 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 158
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 159 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 215
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 216 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 272
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 273 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 332
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 333 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 391
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 392 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 451
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 452 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 511
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 512 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 569
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 570 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 629
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 630 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 687
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 688 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 746
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 747 KEFSEHFRCPPGSPMNPPHKCEVW 770
>BC117256-1|AAI17257.1| 770|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 770
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 99 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 158
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 159 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 215
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 216 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 272
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 273 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 332
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 333 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 391
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 392 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 451
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 452 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 511
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 512 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 569
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 570 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 629
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 630 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 687
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 688 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 746
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 747 KEFSEHFRCPPGSPMNPPHKCEVW 770
>AY953519-1|AAX35820.1| 761|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 761
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 90 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 149
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 150 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 206
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 207 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 263
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 264 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 323
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 324 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 382
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 383 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 442
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 443 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 502
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 503 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 560
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 561 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 620
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 621 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 678
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 679 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 737
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 738 KEFSEHFRCPPGSPMNPPHKCEVW 761
>AL031728-2|CAI19064.1| 754|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 754
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 83 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 142
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 143 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 199
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 200 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 256
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 257 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 316
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 317 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 375
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 376 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 435
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 436 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 495
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 496 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 553
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 554 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 613
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 614 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 671
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 672 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 730
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 731 KEFSEHFRCPPGSPMNPPHKCEVW 754
>AL031728-1|CAB52285.2| 770|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 770
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 99 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 158
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 159 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 215
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 216 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 272
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 273 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 332
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 333 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 391
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 392 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 451
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 452 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 511
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 512 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 569
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 570 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 629
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 630 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 687
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 688 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 746
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 747 KEFSEHFRCPPGSPMNPPHKCEVW 770
>AL031005-4|CAI20195.1| 758|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 758
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 87 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 146
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 147 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 203
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 204 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 260
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 261 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 320
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 321 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 379
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 380 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 439
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 440 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 499
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 500 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 557
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 558 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 617
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 618 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 675
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 676 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 734
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 735 KEFSEHFRCPPGSPMNPPHKCEVW 758
>AL031005-3|CAI20194.1| 754|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 754
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 83 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 142
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 143 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 199
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 200 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 256
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 257 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 316
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 317 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 375
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 376 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 435
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 436 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 495
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 496 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 553
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 554 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 613
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 614 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 671
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 672 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 730
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 731 KEFSEHFRCPPGSPMNPPHKCEVW 754
>AL031005-1|CAI20192.1| 770|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 770
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 99 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 158
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 159 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 215
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 216 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 272
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 273 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 332
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 333 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 391
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 392 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 451
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 452 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 511
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 512 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 569
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 570 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 629
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 630 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 687
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 688 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 746
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 747 KEFSEHFRCPPGSPMNPPHKCEVW 770
>AB031742-1|BAA83687.1| 754|Homo sapiens endothelin-converting
enzyme-1c protein.
Length = 754
Score = 500 bits (1234), Expect = e-141
Identities = 254/684 (37%), Positives = 399/684 (58%), Gaps = 16/684 (2%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + C+ S +L +MD VDPC +F+ +ACG ++K +PD + TFS + + Q
Sbjct: 83 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQA 142
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
I+ LL+ T A+ Y+ACMN T IE +PL+++++RLGGW + W
Sbjct: 143 IIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITG--PW 199
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREY-LNRG 259
+++F Q + A Y F +S D KNS VI +DQ+ LGL SR+Y LN+
Sbjct: 200 AKDNF---QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT 256
Query: 260 FSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 318
++K++ Y YMV + LLG D+ ++++ L FE LANI++P EKRR+ +Y+
Sbjct: 257 ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYH 316
Query: 319 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 378
+T AELQ P + WL ++N + P + ++ +E +V +Y+ + L+ T + +
Sbjct: 317 KVTAAELQTLAPAINWLPFLNTIFYP-VEINESEPIVVYDKEYLEQISTLINTTDRCLLN 375
Query: 379 NYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTERESRWKECADTTSASMSIAVGALY 437
NY++W + + S+L + ++ + G K RWK C T ++ A+G ++
Sbjct: 376 NYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMF 435
Query: 438 IRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEML 497
++ F E+SK+ A E++ +I++ F ++L+ + WMD+ TR+ A EKADA+ + I YP+ ++
Sbjct: 436 VKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIM 495
Query: 498 DNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFY 557
D L + ++ + E+ + F+ +LR+ N+ W P +VNA+Y
Sbjct: 496 DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSM--TPPMVNAYY 553
Query: 558 SSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDW 617
S +N I FPAGILQ F++ P +N+G IG V+GHE+TH FDDQGR++DK+GNL W
Sbjct: 554 SPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPW 613
Query: 618 WQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTH 677
W+ + E + + +C+++QYSNY+V G +NG +T GENIADNGG+K AY AYQ W
Sbjct: 614 WKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK 671
Query: 678 RHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNM 737
++G E LP L + QLF+L A WC+V E+ + T H+P RFRVIG +SN
Sbjct: 672 KNGAEHSLPTL-GLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNS 730
Query: 738 EEFASDFKCPMGSPMNPDKKCKVW 761
+EF+ F+CP GSPMNP KC+VW
Sbjct: 731 KEFSEHFRCPPGSPMNPPHKCEVW 754
>J03779-1|AAA51915.1| 750|Homo sapiens MME protein.
Length = 750
Score = 500 bits (1233), Expect = e-141
Identities = 265/700 (37%), Positives = 405/700 (57%), Gaps = 26/700 (3%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C + CI +A+RL+ NMD +PC +F+ +ACG +LK IP+ + F I+ D+L+
Sbjct: 57 CKSSDCIKSAARLIQNMDATTEPCRDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEV 116
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++ +L EP T E+ AK LY++C+N +AI++RG +PLL +L + GWPV ++W
Sbjct: 117 VLKDVLQEPKT-EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVAT-ENW 174
Query: 202 DEN-SFSW--EQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGL-SREYLN 257
++ SW E+++ + ++ Y ++ + D KNS VI +DQ LGL SR+Y
Sbjct: 175 EQKYGASWTAEKAIAQL-NSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYE 233
Query: 258 -RGFSDKLVQAYYEYMVDIAIL------LGADKTKATEELKESLQFEMKLANISLPLEKR 310
G + AY ++M+ +A L L D+ + E+ + ++ E ++AN + E R
Sbjct: 234 CTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDR 293
Query: 311 RNATSLYNPMTIAELQQKFP------KVPWLEYINRLLAP-HITVDVNELTIVSVPKYIT 363
+ LYN M +A++Q F WL + N +++ +I++ E +V P+Y+T
Sbjct: 294 NDPMLLYNKMRLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLT 353
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
L+ +L K R N + WR VS L+ + + A+ AL G T + W+ CA+
Sbjct: 354 KLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCAN 413
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +M AVG LY+ F SK +++ IR+ F +TL + WMD T++ A EKA
Sbjct: 414 YVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKA 473
Query: 484 DAMASHIAYPSEMLDN-NRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKT 542
A+ I YP +++ N N+L Y L + E+++ F+ KLRE V+K
Sbjct: 474 LAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKD 533
Query: 543 DWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFD 602
+W++ A+VNAFYSS N I FPAGILQ FFSA++ +NYG IG VIGHEITHGFD
Sbjct: 534 EWISGA--AVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFD 591
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEV-GLKLNGVNTQGENIAD 661
D GR F+K+G+LVDWW + + + ++++C++ QY N++ G LNG+NT GENIAD
Sbjct: 592 DNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD 651
Query: 662 NGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
NGG+ +AY AYQ + ++GEE LPGL+ + +QLF+L+ A WC YR E I T
Sbjct: 652 NGGLGQAYRAYQNYIKKNGEEKLLPGLD-LNHKQLFFLNFAQVWCGTYRPEYAVNSIKTD 710
Query: 722 FHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
H+PG FR+IG + N EF+ F C S MNP+KKC+VW
Sbjct: 711 VHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>Y10196-1|CAA71258.1| 749|Homo sapiens PHEX protein.
Length = 749
Score = 487 bits (1201), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW 749
>Y08111-1|CAA69326.1| 749|Homo sapiens PHEX protein.
Length = 749
Score = 487 bits (1201), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW 749
>U87284-1|AAB47562.1| 749|Homo sapiens phosphate regulating neutral
endopeptidase protein.
Length = 749
Score = 487 bits (1201), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW 749
>U75645-1|AAB47749.1| 749|Homo sapiens PEX protein protein.
Length = 749
Score = 487 bits (1201), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW 749
>BC105059-1|AAI05060.1| 749|Homo sapiens X-linked phosphate
regulating endopeptidase homolog protein.
Length = 749
Score = 487 bits (1201), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW 749
>BC105057-1|AAI05058.1| 749|Homo sapiens phosphate regulating
endopeptidase homolog, X-linked (hypophosphatemia,
vitamin protein.
Length = 749
Score = 487 bits (1201), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW 749
>AD000712-1|AAB51604.1| 749|Homo sapiens PEX protein.
Length = 749
Score = 487 bits (1201), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW 749
>U82970-1|AAC24487.1| 749|Homo sapiens metalloendopeptidase homolog
protein.
Length = 749
Score = 487 bits (1200), Expect = e-137
Identities = 264/703 (37%), Positives = 402/703 (57%), Gaps = 26/703 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADN 662
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T GENIADN
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADN 647
Query: 663 GGIKEAYYAYQAWTH--RHG-EEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRIT 719
GG++EA+ AY+ W + R G EE LPG+ ++ QLF+LS A+ C YR EA + ++
Sbjct: 648 GGLREAFRAYRKWINDRRQGLEEPLLPGI-TFTNNQLFFLSYAHVRCNSYRPEAAREQVQ 706
Query: 720 TGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPD-KKCKVW 761
G H+P +FRV G +SN EEF F CP S MN C++W
Sbjct: 707 IGAHSPPQFRVNGAISNSEEFQKAFNCPPNSTMNRGMDSCRLW 749
>BC050453-1|AAH50453.2| 775|Homo sapiens endothelin converting
enzyme-like 1 protein.
Length = 775
Score = 446 bits (1100), Expect = e-124
Identities = 240/698 (34%), Positives = 385/698 (55%), Gaps = 17/698 (2%)
Query: 71 VVARGSDDVETCSAPGCIHTASRLLL-NMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSV 129
V A G E C A+R L N+D +DPC +FY FACG +L+ IPDDK +
Sbjct: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
Query: 130 NTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR 189
T + I +Q +E++R LL P + +++C++ IE G +P+L++++
Sbjct: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
Query: 190 LGGWPVLDGQSWDENSFSWEQSVYKFRDAG-YSVDYFLDFSISVDVKNSTRRVIDLDQAS 248
GGW + + + W+ + ++ G YS ++S+D +NS+R VI +DQ
Sbjct: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
Query: 249 LGLSRE--YLNRGF-SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISL 305
L L YL + S+K++ AY +M + LLGAD + ++ +E LQ E +LANI++
Sbjct: 268 LTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVE--QKAQEILQVEQQLANITV 325
Query: 306 PL--EKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 363
+ RR+ +S+YN +T+ +LQ+ P + W ++++ + + E ++ Y+
Sbjct: 326 SEYDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEE--EEVVLLATDYMQ 383
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
+ L+ TP RV NY++WRV +L+ R + G + + + C
Sbjct: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLG 443
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +A+GAL++ ++F+ SKA ++V DI+ + L ++DWMD TR A K
Sbjct: 444 QANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKL 503
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
M + YP +L + + + Y E+ + +++LN F+ + K+R+ V+K+
Sbjct: 504 QYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKST 562
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 603
W+ P +NA+Y +N + FPAGILQ + P +NYG IG +IGHE+THG+DD
Sbjct: 563 WLLP--PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDD 620
Query: 604 QGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNG 663
G Q+D++GNL+ WW E + ++L KA+CI+ Y N+TV ++NG +T GENIAD G
Sbjct: 621 WGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTV--YNQRVNGKHTLGENIADMG 678
Query: 664 GIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFH 723
G+K AY+AYQ W HG E LP L KY+ QLF+++ A WC R+++I L++ T H
Sbjct: 679 GLKLAYHAYQKWVREHGPEHPLPRL-KYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 737
Query: 724 APGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
AP +RV+G +S EEF F CP SPMNP KC VW
Sbjct: 738 APEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
>AJ130734-1|CAB86601.1| 775|Homo sapiens xce protein.
Length = 775
Score = 446 bits (1100), Expect = e-124
Identities = 240/698 (34%), Positives = 385/698 (55%), Gaps = 17/698 (2%)
Query: 71 VVARGSDDVETCSAPGCIHTASRLLL-NMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSV 129
V A G E C A+R L N+D +DPC +FY FACG +L+ IPDDK +
Sbjct: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
Query: 130 NTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR 189
T + I +Q +E++R LL P + +++C++ IE G +P+L++++
Sbjct: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
Query: 190 LGGWPVLDGQSWDENSFSWEQSVYKFRDAG-YSVDYFLDFSISVDVKNSTRRVIDLDQAS 248
GGW + + + W+ + ++ G YS ++S+D +NS+R VI +DQ
Sbjct: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
Query: 249 LGLSRE--YLNRGF-SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISL 305
L L YL + S+K++ AY +M + LLGAD + ++ +E LQ E +LANI++
Sbjct: 268 LTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVE--QKAQEILQVEQQLANITV 325
Query: 306 PL--EKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 363
+ RR+ +S+YN +T+ +LQ+ P + W ++++ + + E ++ Y+
Sbjct: 326 SEYDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEE--EEVVLLATDYMQ 383
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
+ L+ TP RV NY++WRV +L+ R + G + + + C
Sbjct: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLG 443
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +A+GAL++ ++F+ SKA ++V DI+ + L ++DWMD TR A K
Sbjct: 444 QANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKL 503
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
M + YP +L + + + Y E+ + +++LN F+ + K+R+ V+K+
Sbjct: 504 QYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKST 562
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 603
W+ P +NA+Y +N + FPAGILQ + P +NYG IG +IGHE+THG+DD
Sbjct: 563 WLLP--PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDD 620
Query: 604 QGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNG 663
G Q+D++GNL+ WW E + ++L KA+CI+ Y N+TV ++NG +T GENIAD G
Sbjct: 621 WGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTV--YNQRVNGKHTLGENIADMG 678
Query: 664 GIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFH 723
G+K AY+AYQ W HG E LP L KY+ QLF+++ A WC R+++I L++ T H
Sbjct: 679 GLKLAYHAYQKWVREHGPEHPLPRL-KYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 737
Query: 724 APGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
AP +RV+G +S EEF F CP SPMNP KC VW
Sbjct: 738 APEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
>AC092165-1|AAY24101.1| 775|Homo sapiens unknown protein.
Length = 775
Score = 446 bits (1100), Expect = e-124
Identities = 240/698 (34%), Positives = 385/698 (55%), Gaps = 17/698 (2%)
Query: 71 VVARGSDDVETCSAPGCIHTASRLLL-NMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSV 129
V A G E C A+R L N+D +DPC +FY FACG +L+ IPDDK +
Sbjct: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
Query: 130 NTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR 189
T + I +Q +E++R LL P + +++C++ IE G +P+L++++
Sbjct: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
Query: 190 LGGWPVLDGQSWDENSFSWEQSVYKFRDAG-YSVDYFLDFSISVDVKNSTRRVIDLDQAS 248
GGW + + + W+ + ++ G YS ++S+D +NS+R VI +DQ
Sbjct: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
Query: 249 LGLSRE--YLNRGF-SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISL 305
L L YL + S+K++ AY +M + LLGAD + ++ +E LQ E +LANI++
Sbjct: 268 LTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVE--QKAQEILQVEQQLANITV 325
Query: 306 PL--EKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 363
+ RR+ +S+YN +T+ +LQ+ P + W ++++ + + E ++ Y+
Sbjct: 326 SEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEE--EEVVLLATDYMQ 383
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
+ L+ TP RV NY++WRV +L+ R + G + + + C
Sbjct: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLG 443
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +A+GAL++ ++F+ SKA ++V DI+ + L ++DWMD TR A K
Sbjct: 444 QANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKL 503
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
M + YP +L + + + Y E+ + +++LN F+ + K+R+ V+K+
Sbjct: 504 QYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKST 562
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 603
W+ P +NA+Y +N + FPAGILQ + P +NYG IG +IGHE+THG+DD
Sbjct: 563 WLLP--PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDD 620
Query: 604 QGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNG 663
G Q+D++GNL+ WW E + ++L KA+CI+ Y N+TV ++NG +T GENIAD G
Sbjct: 621 WGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTV--YNQRVNGKHTLGENIADMG 678
Query: 664 GIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFH 723
G+K AY+AYQ W HG E LP L KY+ QLF+++ A WC R+++I L++ T H
Sbjct: 679 GLKLAYHAYQKWVREHGPEHPLPRL-KYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 737
Query: 724 APGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
AP +RV+G +S EEF F CP SPMNP KC VW
Sbjct: 738 APEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
>Y16187-1|CAA76113.1| 775|Homo sapiens metallopeptidase protein.
Length = 775
Score = 442 bits (1090), Expect = e-123
Identities = 239/698 (34%), Positives = 384/698 (55%), Gaps = 17/698 (2%)
Query: 71 VVARGSDDVETCSAPGCIHTASRLLL-NMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSV 129
V A G E C A+R L N+D +DPC +FY FACG +L+ IPDDK +
Sbjct: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
Query: 130 NTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR 189
T + I +Q +E++R LL P + +++C++ IE G +P+L++++
Sbjct: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
Query: 190 LGGWPVLDGQSWDENSFSWEQSVYKFRDAG-YSVDYFLDFSISVDVKNSTRRVIDLDQAS 248
GGW + + + W+ + ++ G YS ++S+D +NS+R VI +DQ
Sbjct: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
Query: 249 LGLSRE--YLNRGF-SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISL 305
L L YL + S+K++ AY +M + LLGAD + ++ +E LQ E +LANI++
Sbjct: 268 LTLPERTLYLAQDEDSEKVLAAYRVFMERVLSLLGADAVE--QKAQEILQVEQQLANITV 325
Query: 306 PL--EKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 363
+ RR+ +S+YN +T+ +LQ+ P + W ++++ + + E ++ Y+
Sbjct: 326 SEYDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEE--EEVVLLATDYMQ 383
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
+ L+ TP RV NY++WRV +L+ R + G + + + C
Sbjct: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLG 443
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +A+GAL++ ++F+ SKA ++V DI+ + L ++DWMD TR A K
Sbjct: 444 QANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKL 503
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
M + YP +L + + + Y E+ + +++LN F+ + K+R+ V+K+
Sbjct: 504 QYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKST 562
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 603
W+ P +NA+Y +N + FPAGILQ + P +NYG IG +IGHE+THG+DD
Sbjct: 563 WLLP--PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDD 620
Query: 604 QGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNG 663
G Q+D++GNL+ WW E + ++L KA+CI+ Y N+TV ++NG +T GENIAD G
Sbjct: 621 WGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTV--YNQRVNGKHTLGENIADMG 678
Query: 664 GIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFH 723
G+K AY+AYQ W HG E LP L KY+ QLF+++ A WC R+++I L++ T H
Sbjct: 679 GLKLAYHAYQKWVREHGPEHPLPRL-KYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 737
Query: 724 APGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
AP +RV+G +S EEF CP SPMNP KC VW
Sbjct: 738 APEHYRVLGSVSQFEEFGRVLHCPKVSPMNPAHKCSVW 775
>AY358923-1|AAQ89282.1| 775|Homo sapiens ECEL1 protein.
Length = 775
Score = 442 bits (1090), Expect = e-123
Identities = 239/698 (34%), Positives = 384/698 (55%), Gaps = 17/698 (2%)
Query: 71 VVARGSDDVETCSAPGCIHTASRLLL-NMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSV 129
V A G E C A+R L N+D +DPC +FY FACG +L+ IPDDK +
Sbjct: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
Query: 130 NTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR 189
T + I +Q +E++R LL P + +++C++ IE G +P+L++++
Sbjct: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
Query: 190 LGGWPVLDGQSWDENSFSWEQSVYKFRDAG-YSVDYFLDFSISVDVKNSTRRVIDLDQAS 248
GGW + + + W+ + ++ G YS ++S+D +NS+R VI +DQ
Sbjct: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
Query: 249 LGLSRE--YLNRGF-SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISL 305
L L YL + S+K++ AY +M + LLGAD + ++ +E LQ E +LANI++
Sbjct: 268 LTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVE--QKAQEILQVEQQLANITV 325
Query: 306 PL--EKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 363
+ RR+ +S+YN +T+ +LQ+ P + W ++++ + + E ++ Y+
Sbjct: 326 SEYDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEE--EEVVLLATDYMQ 383
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
+ L+ TP RV NY++WRV +L+ R + G + + + C
Sbjct: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLG 443
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +A+GAL++ ++F+ SKA ++V DI+ + L ++DWMD TR A K
Sbjct: 444 QANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKL 503
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
M + YP +L + + + Y E+ + +++LN F+ + K+R+ V+K+
Sbjct: 504 QYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIPFSIQLSVKKIRQEVDKST 562
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 603
W+ P +NA+Y +N + FPAGILQ + P +NYG IG +IGHE+THG+DD
Sbjct: 563 WLLP--PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDD 620
Query: 604 QGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNG 663
G Q+D++GNL+ WW E + ++L KA+CI+ Y N+TV ++NG +T GENIAD G
Sbjct: 621 WGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTV--YNQRVNGKHTLGENIADMG 678
Query: 664 GIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFH 723
+K AY+AYQ W HG E LP L KY+ QLF+++ A WC R+++I L++ T H
Sbjct: 679 VLKLAYHAYQKWVREHGPEHPLPRL-KYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 737
Query: 724 APGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
AP +RV+G +S EEF F CP SPMNP KC VW
Sbjct: 738 APEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
>DQ114476-1|AAZ22338.1| 773|Homo sapiens endothelin converting
enzyme-like 1 protein.
Length = 773
Score = 439 bits (1081), Expect = e-122
Identities = 240/698 (34%), Positives = 383/698 (54%), Gaps = 19/698 (2%)
Query: 71 VVARGSDDVETCSAPGCIHTASRLLL-NMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSV 129
V A G E C A+R L N+D +DPC +FY FACG +L+ IPDDK +
Sbjct: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCRDFYSFACGGWLRRHAIPDDKLTY 147
Query: 130 NTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR 189
T + I +Q +E++R LL P + +++C++ IE G +P+L++++
Sbjct: 148 GTIATIGEQNEERLRCLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
Query: 190 LGGWPVLDGQSWDENSFSWEQSVYKFRDAG-YSVDYFLDFSISVDVKNSTRRVIDLDQAS 248
GGW + + + W+ + ++ G YS ++S+D +NS+R VI +DQ
Sbjct: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
Query: 249 LGLSRE--YLNRGF-SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISL 305
L L YL + S+K++ AY M + LLGAD + ++ +E LQ E +LANI++
Sbjct: 268 LTLPERTLYLAQDEDSEKILAAYRVLMERVLSLLGADAVE--QKAQEILQVEQQLANITV 325
Query: 306 PL--EKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 363
+ RR+ +S+YN +T+ +LQ+ P + W ++++ + + E ++ Y+
Sbjct: 326 SEYDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEE--EEVVLLATDYMQ 383
Query: 364 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECAD 423
+ L+ TP RV NY++WRV +L+ R + G + + + C
Sbjct: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLG 443
Query: 424 TTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKA 483
+ +A+GAL++ ++F+ SKA ++V DI+ + L ++DWMD TR A K
Sbjct: 444 QANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKL 503
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
M + YP +L + + + Y E+ + +++LN F+ + K+R+ V+K
Sbjct: 504 QYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDK-- 560
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDD 603
W+ P +NA+Y +N + FPAGILQ + P +NYG IG +IGHE+THG+DD
Sbjct: 561 WLLP--PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDD 618
Query: 604 QGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNG 663
G Q+D++GNL+ WW E + ++L KA+CI+ Y N+TV ++NG +T GENIAD G
Sbjct: 619 WGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTV--YNQRVNGKHTLGENIADMG 676
Query: 664 GIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFH 723
G+K AY+AYQ W HG E LP L KY+ QLF+++ A WC R+++I L++ T H
Sbjct: 677 GLKLAYHAYQKWVREHGPEHPLPRL-KYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 735
Query: 724 APGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
AP +RV+G +S EEF F CP SPMNP KC VW
Sbjct: 736 APEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 773
>U81183-1|AAB42219.1| 633|Homo sapiens phosphate regulator protein.
Length = 633
Score = 388 bits (955), Expect = e-107
Identities = 210/585 (35%), Positives = 329/585 (56%), Gaps = 21/585 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 111
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 112 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 171
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 172 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 230
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 231 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 290
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 291 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 349
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ ANY++WR+ + + L+ + R L + + G T +W +C +
Sbjct: 350 LFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNF 409
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 410 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 469
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 470 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 529
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 530 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 587
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGL 647
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL
Sbjct: 588 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGL 632
>U60475-1|AAC50552.1| 638|Homo sapiens metalloendopeptidase homolog
protein.
Length = 638
Score = 384 bits (945), Expect = e-106
Identities = 210/592 (35%), Positives = 330/592 (55%), Gaps = 21/592 (3%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQL 139
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S + + +
Sbjct: 49 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNV 108
Query: 140 QEQIRSLLDEPVTPEEPRPFVL-AKTLYQACMNRTAIEARGVQPLLDMLKRLG-GWPVLD 197
+++ LL++ ++ + AK LY +CMN AIE +PLL +L+ WPVL+
Sbjct: 109 DLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLE 168
Query: 198 GQS-----WDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS 252
W E FS Q++ FR YS F+ +S D K S ++ LDQA+L L+
Sbjct: 169 SNIGPEGVWSERKFSLLQTLATFRGQ-YSNSVFIRLYVSPDDKASNEHILKLDQATLSLA 227
Query: 253 --REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEK 309
+YL+ K + A Y++MVD A+LLGA+ ++A ++K L+ E+K+A I +P E
Sbjct: 228 VREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHEN 287
Query: 310 RRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHIT-VDVNELTIVSVPKYITD 364
R + ++YN M I+EL P+ WL YI ++ L PH+ + +E +V VP+Y D
Sbjct: 288 R-TSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKD 346
Query: 365 LEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADT 424
L +L K+ NY++WR+ + + L+ + R L + + G T + +C +
Sbjct: 347 LFRILGSERKKTIDNYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQRDKCVNF 406
Query: 425 TSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKV-DWMDDMTRQEALEKA 483
+++ VG +++ YF E+ K E+V +R F L K +WMD T+++A EKA
Sbjct: 407 IESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKA 466
Query: 484 DAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTD 543
A+ + + YP ++++ + E ++ S +VL + + F LR+ V KT+
Sbjct: 467 RAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTE 526
Query: 544 WVTHGRPAIVNAFYSSIENSIQFPAGILQGAFF-SAKRPAYMNYGAIGFVIGHEITHGFD 602
W T+ P VNAFYS+ N I+FPAG LQ FF + P ++YGAIG ++GHE THGFD
Sbjct: 527 WFTN--PTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFD 584
Query: 603 DQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNT 654
+ GR++DKNGNL WW ++EK+ +K KC+I+QYSNY K+ GL + G T
Sbjct: 585 NNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRT 636
>BC101028-1|AAI01029.2| 622|Homo sapiens MMEL1 protein protein.
Length = 622
Score = 352 bits (866), Expect = 2e-96
Identities = 180/471 (38%), Positives = 278/471 (59%), Gaps = 9/471 (1%)
Query: 297 EMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLE--YINRLLAP-HITVDVNEL 353
E A ++P E+R + +LY+ M + ELQ +F + +I +L+ I + +E
Sbjct: 155 ENSTAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNRTLFIQTVLSSVKIKLLPDEE 214
Query: 354 TIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTE 413
+V Y+ +LE +++ R NY++WR+ + L+ + ++ Y AL G
Sbjct: 215 VVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMV 274
Query: 414 RESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDD 473
E RW+EC +++M AVG+LY+R+ F +SK+ E+++ +R F +TL ++ WMD+
Sbjct: 275 EEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDE 334
Query: 474 MTRQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYL 531
++++A EKA ++ I +P +L+ N RL E YS L S + E+ L +
Sbjct: 335 ESKKKAQEKAMSIREQIGHPDYILEETNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRS 394
Query: 532 FGKLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGF 591
KLRE V+ W+ A+VNAFYS N I FPAGILQ FFS ++P +N+G IG
Sbjct: 395 LRKLREKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGM 452
Query: 592 VIGHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVG-LKLN 650
VIGHEITHGFDD GR FDKNGN++DWW + + + ++++C+I QY NY+ +N
Sbjct: 453 VIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVN 512
Query: 651 GVNTQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYR 710
G NT GENIADNGG+++AY AY W G++ +LPGL+ + QLF+++ A WC YR
Sbjct: 513 GFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLD-LTHEQLFFINYAQVWCGSYR 571
Query: 711 NEAIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
E I T H+P ++RV+G + N+ FA F C G+PM+P ++C+VW
Sbjct: 572 PEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 622
Score = 77.0 bits (181), Expect = 2e-13
Identities = 33/98 (33%), Positives = 58/98 (59%), Gaps = 4/98 (4%)
Query: 69 PAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTS 128
P + + E C+ PGC+ A+R+L NMD +PCD+FY FACG +L+ IP+ +
Sbjct: 76 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 135
Query: 129 VNTFSIITDQLQEQIRSLLD----EPVTPEEPRPFVLA 162
+ F ++ D+L+ ++++L+ + P+E R V+A
Sbjct: 136 YSIFDVLRDELEVILKAVLENSTAKATVPQEERHDVIA 173
>BC101029-1|AAI01030.1| 611|Homo sapiens MMEL1 protein protein.
Length = 611
Score = 296 bits (727), Expect = 2e-79
Identities = 170/513 (33%), Positives = 286/513 (55%), Gaps = 19/513 (3%)
Query: 69 PAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTS 128
P + + E C+ PGC+ A+R+L NMD +PCD+FY FACG +L+ IP+ +
Sbjct: 76 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 135
Query: 129 VNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLK 188
+ F ++ D+L+ ++++L+ + P A+TLY++CMN++ IE RG QPLLD+L+
Sbjct: 136 YSIFDVLRDELEVILKAVLENSTAKDRPA-VEKARTLYRSCMNQSVIEKRGSQPLLDILE 194
Query: 189 RLGGWPVLDGQSWDEN-SFSWE-QSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQ 246
+GGWPV + W+E WE + ++ ++ +D I D +NS+R +I +DQ
Sbjct: 195 VVGGWPVAMDR-WNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 253
Query: 247 ASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK------ATEELKESLQFEM 298
+LG+ SREY N G + K+ +AY ++MV +A LL D E++ + L+ E
Sbjct: 254 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
Query: 299 KLANISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP-HITVDVNELTI 355
+LA ++P E+R + +LY+ M + ELQ +F W +I +L+ I + +E +
Sbjct: 314 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 373
Query: 356 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 415
V Y+ +LE +++ R NY++WR+ + L+ + ++ Y AL G E
Sbjct: 374 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 433
Query: 416 SRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMT 475
RW+EC +++M AVG+LY+R+ F +SK+ E+++ +R F +TL ++ WMD+ +
Sbjct: 434 VRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEES 493
Query: 476 RQEALEKADAMASHIAYPSEMLD--NNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFG 533
+++A EKA ++ I +P +L+ N RL E YS L S + E+ L +
Sbjct: 494 KKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLR 553
Query: 534 KLREPVNKTDWVTHGRPAIVNAFYSSIENSIQF 566
KLRE V+ W+ A+VNAFYS N I +
Sbjct: 554 KLREKVDPNLWIIGA--AVVNAFYSPNRNQIAY 584
>AM085120-1|CAJ30274.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 212 bits (517), Expect = 5e-54
Identities = 173/692 (25%), Positives = 310/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ AFF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPAFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>M64934-1|AAA03192.1| 732|Homo sapiens kell blood group protein
protein.
Length = 732
Score = 211 bits (516), Expect = 6e-54
Identities = 170/689 (24%), Positives = 305/689 (44%), Gaps = 42/689 (6%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++R +L+ + A Y +CM+ AIEA G PL +++ LGGW + W
Sbjct: 128 RLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI--SGKW 185
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYLNRGF 260
+F+ + + Y F + + VI +DQ + ++ +
Sbjct: 186 TSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQKI 242
Query: 261 SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 320
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +
Sbjct: 243 YAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMV 302
Query: 321 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLE----KTPKRV 376
TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E K +
Sbjct: 303 TIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDFL 361
Query: 377 QANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASMSIA 432
Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 362 QSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPT 421
Query: 433 VGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAY 492
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K + +
Sbjct: 422 LAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMGA 481
Query: 493 PSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAI 552
L + Y+ +++ S L +SVL+ + +P + W P
Sbjct: 482 SEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS--PWD 538
Query: 553 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNG 612
VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q G
Sbjct: 539 VNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLLLPG 594
Query: 613 NLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAY 672
+ +E +L C+ Y+ + + N T EN AD GG+ A AY
Sbjct: 595 GCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIALQAY 649
Query: 673 QAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIG 732
RH E LP L+ SP+Q+F+ S A C R + + T H+P RV G
Sbjct: 650 SKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLRVHG 703
Query: 733 PMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
P+S+ FA F+C G+ +NP +C++W
Sbjct: 704 PLSSTPAFARYFRCARGALLNPSSRCQLW 732
>BC050639-1|AAH50639.1| 732|Homo sapiens Kell blood group,
metallo-endopeptidase protein.
Length = 732
Score = 211 bits (516), Expect = 6e-54
Identities = 170/689 (24%), Positives = 305/689 (44%), Gaps = 42/689 (6%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++R +L+ + A Y +CM+ AIEA G PL +++ LGGW + W
Sbjct: 128 RLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI--SGKW 185
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYLNRGF 260
+F+ + + Y F + + VI +DQ + ++ +
Sbjct: 186 TSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQKI 242
Query: 261 SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 320
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +
Sbjct: 243 YAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMV 302
Query: 321 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLE----KTPKRV 376
TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E K +
Sbjct: 303 TIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDFL 361
Query: 377 QANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASMSIA 432
Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 362 QSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPT 421
Query: 433 VGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAY 492
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K + +
Sbjct: 422 LAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMGA 481
Query: 493 PSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAI 552
L + Y+ +++ S L +SVL+ + +P + W P
Sbjct: 482 SEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS--PWD 538
Query: 553 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNG 612
VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q G
Sbjct: 539 VNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLLLPG 594
Query: 613 NLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAY 672
+ +E +L C+ Y+ + + N T EN AD GG+ A AY
Sbjct: 595 GCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIALQAY 649
Query: 673 QAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIG 732
RH E LP L+ SP+Q+F+ S A C R + + T H+P RV G
Sbjct: 650 SKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLRVHG 703
Query: 733 PMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
P+S+ FA F+C G+ +NP +C++W
Sbjct: 704 PLSSTPAFARYFRCARGALLNPSSRCQLW 732
>BC003135-1|AAH03135.1| 732|Homo sapiens Kell blood group,
metallo-endopeptidase protein.
Length = 732
Score = 211 bits (516), Expect = 6e-54
Identities = 170/689 (24%), Positives = 305/689 (44%), Gaps = 42/689 (6%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++R +L+ + A Y +CM+ AIEA G PL +++ LGGW + W
Sbjct: 128 RLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI--SGKW 185
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYLNRGF 260
+F+ + + Y F + + VI +DQ + ++ +
Sbjct: 186 TSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQKI 242
Query: 261 SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 320
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +
Sbjct: 243 YAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMV 302
Query: 321 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLE----KTPKRV 376
TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E K +
Sbjct: 303 TIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDFL 361
Query: 377 QANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASMSIA 432
Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 362 QSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPT 421
Query: 433 VGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAY 492
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K + +
Sbjct: 422 LAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMGA 481
Query: 493 PSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAI 552
L + Y+ +++ S L +SVL+ + +P + W P
Sbjct: 482 SEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS--PWD 538
Query: 553 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNG 612
VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q G
Sbjct: 539 VNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLLLPG 594
Query: 613 NLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAY 672
+ +E +L C+ Y+ + + N T EN AD GG+ A AY
Sbjct: 595 GCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIALQAY 649
Query: 673 QAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIG 732
RH E LP L+ SP+Q+F+ S A C R + + T H+P RV G
Sbjct: 650 SKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLRVHG 703
Query: 733 PMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
P+S+ FA F+C G+ +NP +C++W
Sbjct: 704 PLSSTPAFARYFRCARGALLNPSSRCQLW 732
>AY228336-1|AAO38053.1| 732|Homo sapiens Kell blood group protein.
Length = 732
Score = 211 bits (516), Expect = 6e-54
Identities = 170/689 (24%), Positives = 305/689 (44%), Gaps = 42/689 (6%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++R +L+ + A Y +CM+ AIEA G PL +++ LGGW + W
Sbjct: 128 RLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI--SGKW 185
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYLNRGF 260
+F+ + + Y F + + VI +DQ + ++ +
Sbjct: 186 TSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQKI 242
Query: 261 SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 320
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +
Sbjct: 243 YAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMV 302
Query: 321 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLE----KTPKRV 376
TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E K +
Sbjct: 303 TIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDFL 361
Query: 377 QANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASMSIA 432
Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 362 QSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPT 421
Query: 433 VGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAY 492
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K + +
Sbjct: 422 LAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMGA 481
Query: 493 PSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAI 552
L + Y+ +++ S L +SVL+ + +P + W P
Sbjct: 482 SEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS--PWD 538
Query: 553 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNG 612
VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q G
Sbjct: 539 VNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLLLPG 594
Query: 613 NLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAY 672
+ +E +L C+ Y+ + + N T EN AD GG+ A AY
Sbjct: 595 GCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIALQAY 649
Query: 673 QAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIG 732
RH E LP L+ SP+Q+F+ S A C R + + T H+P RV G
Sbjct: 650 SKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLRVHG 703
Query: 733 PMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
P+S+ FA F+C G+ +NP +C++W
Sbjct: 704 PLSSTPAFARYFRCARGALLNPSSRCQLW 732
>AF172627-1|AAB33459.1| 732|Homo sapiens Kell protein protein.
Length = 732
Score = 211 bits (516), Expect = 6e-54
Identities = 170/689 (24%), Positives = 305/689 (44%), Gaps = 42/689 (6%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSW 201
++R +L+ + A Y +CM+ AIEA G PL +++ LGGW + W
Sbjct: 128 RLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI--SGKW 185
Query: 202 DENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYLNRGF 260
+F+ + + Y F + + VI +DQ + ++ +
Sbjct: 186 TSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQKI 242
Query: 261 SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 320
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +
Sbjct: 243 YAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMV 302
Query: 321 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLE----KTPKRV 376
TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E K +
Sbjct: 303 TIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDFL 361
Query: 377 QANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASMSIA 432
Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 362 QSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPT 421
Query: 433 VGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAY 492
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K + +
Sbjct: 422 LAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMGA 481
Query: 493 PSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAI 552
L + Y+ +++ S L +SVL+ + +P + W P
Sbjct: 482 SEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS--PWD 538
Query: 553 VNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNG 612
VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q G
Sbjct: 539 VNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLLLPG 594
Query: 613 NLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAY 672
+ +E +L C+ Y+ + + N T EN AD GG+ A AY
Sbjct: 595 GCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIALQAY 649
Query: 673 QAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIG 732
RH E LP L+ SP+Q+F+ S A C R + + T H+P RV G
Sbjct: 650 SKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLRVHG 703
Query: 733 PMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
P+S+ FA F+C G+ +NP +C++W
Sbjct: 704 PLSSTPAFARYFRCARGALLNPSSRCQLW 732
>AM085116-1|CAJ30270.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 210 bits (514), Expect = 1e-53
Identities = 172/692 (24%), Positives = 309/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSCAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085124-1|CAJ30278.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 210 bits (512), Expect = 2e-53
Identities = 172/692 (24%), Positives = 309/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085117-1|CAJ30271.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 210 bits (512), Expect = 2e-53
Identities = 172/692 (24%), Positives = 309/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085115-1|CAJ30269.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 210 bits (512), Expect = 2e-53
Identities = 172/692 (24%), Positives = 309/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085113-1|CAJ30267.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 210 bits (512), Expect = 2e-53
Identities = 172/692 (24%), Positives = 309/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085121-1|CAJ30275.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 209 bits (511), Expect = 2e-53
Identities = 172/692 (24%), Positives = 309/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----CQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085123-1|CAJ30277.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 208 bits (509), Expect = 4e-53
Identities = 172/692 (24%), Positives = 308/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTEFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGLSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085119-1|CAJ30273.1| 730|Homo sapiens kell blood group antigen
Cellano protein.
Length = 730
Score = 208 bits (507), Expect = 7e-53
Identities = 172/692 (24%), Positives = 308/692 (44%), Gaps = 50/692 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSWLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFR 729
AY RH E LP L+ SP+Q+F+ S A C R + + T H+P R
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFFRSYAQVMC---RKPSPQDSHDT--HSPPHLR 698
Query: 730 VIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
V GP+S+ FA F+C G+ +NP +C++W
Sbjct: 699 VHGPLSSTPAFARYFRCARGALLNPSSRCQLW 730
>AM085118-1|CAJ30272.1| 672|Homo sapiens truncated kell blood group
antigen Cellano protein.
Length = 672
Score = 176 bits (428), Expect = 3e-43
Identities = 151/629 (24%), Positives = 277/629 (44%), Gaps = 45/629 (7%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR- 375
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+ +
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQ 356
Query: 376 --VQANYVMWRVAGASVSYLTD--DLRRRQLAYITALSGKTERESR--WKECADTTSASM 429
+Q++ ++ V S + + + RR+ + L+ + +R W +C + T
Sbjct: 357 DFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFF 416
Query: 430 SIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWMDDMTRQEALEKADAMASH 489
+ AL++R+ F ++++ A+++ IR L + WM++ T+ A +K +
Sbjct: 417 EPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVE 476
Query: 490 IAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGR 549
+ L + Y+ +++ S L +SVL+ + +P + W
Sbjct: 477 MGASEWALKPELARQEYNDIQLGSSFL-QSVLSCVRSLRARIVQSFLQPHPQHRWKVS-- 533
Query: 550 PAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFD 609
P VNA+YS ++ + FPAG+LQ FF P +N+GA G ++ HE+ H F Q
Sbjct: 534 PWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF----YQLL 589
Query: 610 KNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAY 669
G + +E +L C+ Y+ + + N T EN AD GG+ A
Sbjct: 590 LPGGCLACDNHALQEAHL----CLKRHYAAFPLPS-RTSFNDSLTFLENAADVGGLAIAL 644
Query: 670 YAYQAWTHRHGEEARLPGLEKYSPRQLFW 698
AY RH E LP L+ SP+Q+F+
Sbjct: 645 QAYSKRLLRHHGETVLPSLD-LSPQQIFF 672
>AL031005-2|CAI20193.1| 197|Homo sapiens endothelin converting
enzyme 1 protein.
Length = 197
Score = 154 bits (373), Expect = 1e-36
Identities = 74/162 (45%), Positives = 105/162 (64%), Gaps = 9/162 (5%)
Query: 534 KLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVI 593
+LR+ N+ W P +VNA+YS +N I FPAGILQ F++ P +N+G IG V+
Sbjct: 7 QLRKAPNRDQWSM--TPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVV 64
Query: 594 GHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVN 653
GHE+TH FDDQGR++DK+GNL WW+ + E + + +C+++QYSNY+V G +NG +
Sbjct: 65 GHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVN--GEPVNGRH 122
Query: 654 TQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGL--EKYSP 693
T GENIADNGG+K AY+ W E+ GL + +SP
Sbjct: 123 TLGENIADNGGLKA---AYRVWCSVRTPESSHEGLITDPHSP 161
Score = 74.5 bits (175), Expect = 1e-12
Identities = 31/62 (50%), Positives = 41/62 (66%)
Query: 700 SAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCK 759
+A WC+V E+ + T H+P RFRVIG +SN +EF+ F+CP GSPMNP KC+
Sbjct: 136 AAYRVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCE 195
Query: 760 VW 761
VW
Sbjct: 196 VW 197
>AB030579-1|BAC66225.1| 306|Homo sapiens endotheline-converting
enzyme ECEL1 protein.
Length = 306
Score = 103 bits (248), Expect = 2e-21
Identities = 58/188 (30%), Positives = 95/188 (50%), Gaps = 2/188 (1%)
Query: 71 VVARGSDDVETCSAPGCIHTASRLLL-NMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSV 129
V A G E C A+R L N+D +DPC +FY FACG +L+ IPDDK +
Sbjct: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
Query: 130 NTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKR 189
T + I +Q +E++R LL P + +++C++ IE G +P+L++++
Sbjct: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
Query: 190 LGGWPVLDGQSWDENSFSWEQSVYKFRDAG-YSVDYFLDFSISVDVKNSTRRVIDLDQAS 248
GGW + + + W+ + ++ G YS ++S+D +NS+R VI +DQ
Sbjct: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
Query: 249 LGLSREYL 256
L L L
Sbjct: 268 LTLPERTL 275
>AM085114-1|CAJ30268.1| 403|Homo sapiens truncated kell blood group
antigen Cellano protein.
Length = 403
Score = 89.0 bits (211), Expect = 5e-17
Identities = 69/295 (23%), Positives = 129/295 (43%), Gaps = 25/295 (8%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEK 371
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++ L+E+
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEE 351
>AM085122-1|CAJ30276.1| 346|Homo sapiens truncated kell blood group
antigen Cellano protein.
Length = 346
Score = 85.0 bits (201), Expect = 9e-16
Identities = 67/289 (23%), Positives = 125/289 (43%), Gaps = 25/289 (8%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQE 141
C C+ L + + V PC +F+ FACG K + N+F + + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRA---------KETNNSFQELATKNKN 127
Query: 142 QIRSLLDE----PVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLD 197
++R +L + P + EE A Y +CM+ AIEA G PL +++ LGGW +
Sbjct: 128 RLRRILVQNSWHPGSGEEK-----AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRI-- 180
Query: 198 GQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLS-REYL 256
W +F+ + + Y F + + VI +DQ + ++
Sbjct: 181 SGKWTSLNFN---RTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQ 237
Query: 257 NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSL 316
+ ++ + Y Y+ + LLG D +K E S+ +L PLE+RR L
Sbjct: 238 EQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL 297
Query: 317 YNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDL 365
+ +TI +L++ P + WL + P +++ ++ +V +Y+ ++
Sbjct: 298 FQMVTIDQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNM 345
>AF018034-1|AAD21221.1| 58|Homo sapiens endothelin converting
enzyme-1 protein.
Length = 58
Score = 73.3 bits (172), Expect = 3e-12
Identities = 30/57 (52%), Positives = 39/57 (68%)
Query: 705 WCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW 761
WC+V E+ + T H+P RFRVIG +SN +EF+ F+CP GSPMNP KC+VW
Sbjct: 2 WCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 58
>U73024-1|AAD08630.1| 116|Homo sapiens phosphate regulating neutral
endopeptidase PEX protein.
Length = 116
Score = 55.2 bits (127), Expect = 8e-07
Identities = 22/53 (41%), Positives = 31/53 (58%)
Query: 80 ETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTF 132
E C P CI A+ +L ++ VDPCDNF+ FAC ++ N IP+D S +
Sbjct: 52 EYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVY 104
>AM085127-1|CAJ30281.1| 177|Homo sapiens kell blood group antigen
Cellano protein.
Length = 177
Score = 54.0 bits (124), Expect = 2e-06
Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
Query: 263 KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 322
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +TI
Sbjct: 21 QIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTI 80
Query: 323 AELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEK 371
+L++ P + WL + P +++ ++ +V +Y+ ++ L+E+
Sbjct: 81 DQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEE 128
>AM085128-1|CAJ30282.1| 91|Homo sapiens truncated kell blood group
antigen Cellano protein.
Length = 91
Score = 41.1 bits (92), Expect = 0.014
Identities = 20/70 (28%), Positives = 35/70 (50%)
Query: 263 KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 322
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +TI
Sbjct: 21 QIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTI 80
Query: 323 AELQQKFPKV 332
+L++ P +
Sbjct: 81 DQLKEMAPAI 90
>AJ130828-1|CAB46443.1| 129|Homo sapiens human
endothelin-converting enzyme-1 d isoform protein.
Length = 129
Score = 41.1 bits (92), Expect = 0.014
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 82 CSAPGCIHTASRLLLNMDEKVDPCDNFYDFACG 114
C + C+ S +L +MD VDPC +F+ +ACG
Sbjct: 96 CLSEACVSVTSSILSSMDPTVDPCHDFFSYACG 128
>DQ923321-1|ABI96895.1| 84|Homo sapiens kell blood group protein
protein.
Length = 84
Score = 37.9 bits (84), Expect = 0.13
Identities = 19/64 (29%), Positives = 32/64 (50%)
Query: 263 KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 322
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +TI
Sbjct: 21 QIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTI 80
Query: 323 AELQ 326
+L+
Sbjct: 81 DQLK 84
>AF279657-1|AAK69488.1| 84|Homo sapiens Kell blood group protein
protein.
Length = 84
Score = 37.9 bits (84), Expect = 0.13
Identities = 19/64 (29%), Positives = 32/64 (50%)
Query: 263 KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 322
++ + Y Y+ + LLG D +K E S+ +L PLE+RR L+ +TI
Sbjct: 21 QIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTI 80
Query: 323 AELQ 326
+L+
Sbjct: 81 DQLK 84
>AM183928-1|CAJ75457.1| 63|Homo sapiens Kell blood group antigen,
weak k protein.
Length = 63
Score = 35.5 bits (78), Expect = 0.71
Identities = 19/63 (30%), Positives = 30/63 (47%)
Query: 264 LVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIA 323
+ + Y Y+ + LLG D +K E S+ L PLE+RR L+ +TI
Sbjct: 1 IFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSWLFQFLRPLEQRRAQGKLFQMVTID 60
Query: 324 ELQ 326
+L+
Sbjct: 61 QLK 63
>AJ012371-1|CAB39968.1| 740|Homo sapiens NAALADase L protein
protein.
Length = 740
Score = 34.7 bits (76), Expect = 1.2
Identities = 16/56 (28%), Positives = 24/56 (42%)
Query: 666 KEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
+E YY++ W HG + +PGL R S + W V R +I + G
Sbjct: 674 EERYYSHVLWAPSHGLRSHIPGLSNACSRARDTASGSEAWAEVQRQLSIVVTALEG 729
>AF010141-1|AAB87645.1| 322|Homo sapiens peptidase homolog protein.
Length = 322
Score = 34.7 bits (76), Expect = 1.2
Identities = 16/56 (28%), Positives = 24/56 (42%)
Query: 666 KEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTG 721
+E YY++ W HG + +PGL R S + W V R +I + G
Sbjct: 256 EERYYSHVLWAPSHGLRSHIPGLSNACSRARDTASGSEAWAEVQRQLSIVVTALEG 311
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.133 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,349,489
Number of Sequences: 224733
Number of extensions: 4356334
Number of successful extensions: 8279
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 7696
Number of HSP's gapped (non-prelim): 80
length of query: 761
length of database: 73,234,838
effective HSP length: 96
effective length of query: 665
effective length of database: 51,660,470
effective search space: 34354212550
effective search space used: 34354212550
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)
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