Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000511-TA|BGIBMGA000511-PA|IPR002347|Glucose/ribitol
dehydrogenase, IPR002198|Short-chain dehydrogenase/reductase SDR
(255 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O18404 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2;... 345 9e-94
UniRef50_Q99714 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2;... 340 2e-92
UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ... 287 2e-76
UniRef50_Q128N5 Cluster: Short-chain dehydrogenase/reductase SDR... 270 2e-71
UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 264 1e-69
UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR... 256 3e-67
UniRef50_Q86JE3 Cluster: Similar to Oceanobacillus iheyensis. 3-... 252 5e-66
UniRef50_A7RVM1 Cluster: Predicted protein; n=1; Nematostella ve... 248 1e-64
UniRef50_A1W286 Cluster: Short-chain dehydrogenase/reductase SDR... 245 1e-63
UniRef50_Q128L4 Cluster: Short-chain dehydrogenase/reductase SDR... 244 2e-63
UniRef50_A5V768 Cluster: Short-chain dehydrogenase/reductase SDR... 241 2e-62
UniRef50_Q28UN1 Cluster: Short-chain dehydrogenase/reductase SDR... 237 2e-61
UniRef50_Q9ABU6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=13; ... 235 6e-61
UniRef50_A1SNF3 Cluster: Short-chain dehydrogenase/reductase SDR... 226 4e-58
UniRef50_A0YH24 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; m... 220 2e-56
UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya... 206 6e-52
UniRef50_A0GPG2 Cluster: Short-chain dehydrogenase/reductase SDR... 204 2e-51
UniRef50_Q1B5D1 Cluster: Short-chain dehydrogenase/reductase SDR... 202 9e-51
UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;... 194 2e-48
UniRef50_Q1GUS0 Cluster: Short-chain dehydrogenase/reductase SDR... 186 5e-46
UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena... 184 2e-45
UniRef50_Q4P9D8 Cluster: Putative uncharacterized protein; n=1; ... 171 1e-41
UniRef50_Q93SJ3 Cluster: USC5-2p; n=1; Myxococcus xanthus|Rep: U... 166 4e-40
UniRef50_Q236S0 Cluster: Oxidoreductase, short chain dehydrogena... 151 2e-35
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 149 9e-35
UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 148 2e-34
UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 144 3e-33
UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR... 142 8e-33
UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 141 1e-32
UniRef50_A3FQ12 Cluster: Scully CG7113-PA, putative; n=2; Crypto... 141 1e-32
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 141 2e-32
UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M... 140 3e-32
UniRef50_Q19246 Cluster: Dehydrogenases, short chain protein 25;... 139 7e-32
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 137 3e-31
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 136 7e-31
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 134 2e-30
UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 134 2e-30
UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 133 4e-30
UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 132 6e-30
UniRef50_Q94G10 Cluster: CTA; n=3; Cucumis sativus|Rep: CTA - Cu... 131 2e-29
UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 130 3e-29
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 130 4e-29
UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR... 129 6e-29
UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR... 129 8e-29
UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 127 3e-28
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 126 4e-28
UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-su... 126 7e-28
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 125 1e-27
UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta... 125 1e-27
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 125 1e-27
UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 125 1e-27
UniRef50_Q9LW34 Cluster: Alcohol dehydrogenase-like protein; n=6... 124 2e-27
UniRef50_A7RXH2 Cluster: Predicted protein; n=1; Nematostella ve... 124 2e-27
UniRef50_A4L2T8 Cluster: FabG; n=24; Lactobacillales|Rep: FabG -... 124 3e-27
UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 124 3e-27
UniRef50_Q5LDH2 Cluster: Putative 2,5-dichloro-2,5-cyclohexadien... 122 7e-27
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 122 7e-27
UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 122 7e-27
UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 122 1e-26
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 121 2e-26
UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 121 2e-26
UniRef50_Q7NFL8 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 121 2e-26
UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 121 2e-26
UniRef50_Q9W4U2 Cluster: CG3603-PA; n=8; Neoptera|Rep: CG3603-PA... 121 2e-26
UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD... 120 3e-26
UniRef50_Q0LZB7 Cluster: NAD-dependent epimerase/dehydratase:Sho... 120 3e-26
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 120 3e-26
UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 120 4e-26
UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR... 120 4e-26
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 120 4e-26
UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR... 120 4e-26
UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2; Bacteri... 120 5e-26
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR... 119 6e-26
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 119 6e-26
UniRef50_Q1GRW4 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 118 1e-25
UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 118 1e-25
UniRef50_Q53217 Cluster: Uncharacterized short-chain type dehydr... 118 1e-25
UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel... 118 1e-25
UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 118 1e-25
UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR... 118 1e-25
UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida... 118 1e-25
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 118 2e-25
UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 118 2e-25
UniRef50_Q93HC0 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 117 3e-25
UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 117 3e-25
UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 117 3e-25
UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protei... 117 3e-25
UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 117 3e-25
UniRef50_Q2UB90 Cluster: Dehydrogenases with different specifici... 117 3e-25
UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 117 3e-25
UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like ... 117 3e-25
UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 117 3e-25
UniRef50_A4F720 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 117 3e-25
UniRef50_A3PQM4 Cluster: Short-chain dehydrogenase/reductase SDR... 117 3e-25
UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 117 3e-25
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 116 4e-25
UniRef50_Q03RV5 Cluster: 3-oxoacyl-acyl carrier protein reductas... 116 4e-25
UniRef50_A1R756 Cluster: Putative 3-oxoacyl-(Acyl carrier protei... 116 4e-25
UniRef50_Q0U998 Cluster: Putative uncharacterized protein; n=1; ... 116 4e-25
UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductas... 116 6e-25
UniRef50_A3K113 Cluster: Short chain dehydrogenase; n=1; Sagittu... 116 6e-25
UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 116 8e-25
UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 115 1e-24
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 115 1e-24
UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24
UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo... 115 1e-24
UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 115 1e-24
UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24
UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 115 1e-24
UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24
UniRef50_P50160 Cluster: Sex determination protein tasselseed-2;... 115 1e-24
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 114 2e-24
UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR... 114 2e-24
UniRef50_A6W805 Cluster: Short-chain dehydrogenase/reductase SDR... 114 2e-24
UniRef50_Q29HP4 Cluster: GA17551-PA; n=1; Drosophila pseudoobscu... 114 2e-24
UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2; Pichi... 114 2e-24
UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 114 2e-24
UniRef50_Q67RY1 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei... 114 2e-24
UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR... 114 2e-24
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 114 2e-24
UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 113 3e-24
UniRef50_Q46NA6 Cluster: NAD-dependent epimerase/dehydratase:Sho... 113 3e-24
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 113 4e-24
UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 113 4e-24
UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;... 113 4e-24
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 113 4e-24
UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo... 113 4e-24
UniRef50_Q92506 Cluster: Estradiol 17-beta-dehydrogenase 8; n=38... 113 4e-24
UniRef50_Q7W7A0 Cluster: Probable 3-oxoacyl-[acyl-carrier protei... 113 5e-24
UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 113 5e-24
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 113 5e-24
UniRef50_A4BPE5 Cluster: Acetoacetyl-CoA reductase; n=5; Gammapr... 113 5e-24
UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 113 5e-24
UniRef50_Q8WTW8 Cluster: Carbonyl reductase 4; n=25; Euteleostom... 113 5e-24
UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase fam... 113 5e-24
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 112 7e-24
UniRef50_Q1AU84 Cluster: Short-chain dehydrogenase/reductase SDR... 112 7e-24
UniRef50_Q1ASH3 Cluster: Short-chain dehydrogenase/reductase SDR... 112 7e-24
UniRef50_A0PWM6 Cluster: Short-chain type dehydrogenase/reductas... 112 7e-24
UniRef50_Q0V6D8 Cluster: Putative uncharacterized protein; n=1; ... 112 7e-24
UniRef50_Q0U4L0 Cluster: Putative uncharacterized protein; n=3; ... 112 7e-24
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 112 9e-24
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 112 9e-24
UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 112 9e-24
UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 112 9e-24
UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 112 9e-24
UniRef50_Q6MLJ7 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 111 1e-23
UniRef50_Q53WH2 Cluster: 3-oxoacyl-[acyl carrier protein] reduct... 111 1e-23
UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR... 111 1e-23
UniRef50_A4XF74 Cluster: Short-chain dehydrogenase/reductase SDR... 111 1e-23
UniRef50_A3ZUW7 Cluster: Putative oxidoreductase; n=1; Blastopir... 111 1e-23
UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 111 1e-23
UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 111 2e-23
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 111 2e-23
UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 111 2e-23
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_A3Q4Y4 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOH... 110 3e-23
UniRef50_Q39FN1 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 110 3e-23
UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 110 3e-23
UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:... 110 3e-23
UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23
UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine ... 110 4e-23
UniRef50_A1DKS5 Cluster: Short chain dehydrogenase/reductase fam... 110 4e-23
UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 110 4e-23
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 110 4e-23
UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 110 4e-23
UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 109 5e-23
UniRef50_Q12DF3 Cluster: Short-chain dehydrogenase/reductase SDR... 109 5e-23
UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR... 109 5e-23
UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 109 5e-23
UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 109 5e-23
UniRef50_Q9LW35 Cluster: Alcohol dehydrogenase-like protein; n=6... 109 5e-23
UniRef50_Q76KV8 Cluster: Short-chain alcohol dehydrogenase A; n=... 109 5e-23
UniRef50_P14697 Cluster: Acetoacetyl-CoA reductase; n=25; Bacter... 109 5e-23
UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 109 7e-23
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 109 7e-23
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 109 7e-23
UniRef50_Q2CHI2 Cluster: Short-chain dehydrogenase/reductase SDR... 109 7e-23
UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ... 109 7e-23
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 109 7e-23
UniRef50_Q14RS1 Cluster: ABA4 protein; n=4; Pezizomycotina|Rep: ... 109 7e-23
UniRef50_Q8ZVW5 Cluster: Short chain dehydrogenase family; n=3; ... 109 7e-23
UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 109 9e-23
UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Re... 109 9e-23
UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodoco... 109 9e-23
UniRef50_A4XEN1 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23
UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or... 109 9e-23
UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 109 9e-23
UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 109 9e-23
UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetell... 108 1e-22
UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein... 108 1e-22
UniRef50_Q2IT70 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_A4M0F5 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 108 1e-22
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 108 1e-22
UniRef50_Q930L3 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat... 108 2e-22
UniRef50_Q1NAA1 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_A6F000 Cluster: Putative short-chain dehydrogenase/redu... 108 2e-22
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_Q2UNR9 Cluster: Dehydrogenases with different specifici... 108 2e-22
UniRef50_Q9LBG2 Cluster: Levodione reductase (EC 1.1.1.-) ((6R)-... 108 2e-22
UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 107 2e-22
UniRef50_A4E921 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-22
UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter... 107 2e-22
UniRef50_A2QZI1 Cluster: Contig An12c0160, complete genome; n=1;... 107 2e-22
UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 107 2e-22
UniRef50_Q97UA4 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 107 2e-22
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 107 2e-22
UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 107 2e-22
UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 107 3e-22
UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 107 3e-22
UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR... 107 3e-22
UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 107 3e-22
UniRef50_Q9F5J1 Cluster: SimJ1; n=5; Actinomycetales|Rep: SimJ1 ... 107 3e-22
UniRef50_Q0RYT0 Cluster: Short-chain alcohol dehydrogenase; n=4;... 107 3e-22
UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei... 107 3e-22
UniRef50_A4QV37 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 107 3e-22
UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogena... 107 4e-22
UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 107 4e-22
UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 107 4e-22
UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 107 4e-22
UniRef50_A5P615 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 107 4e-22
UniRef50_A2ULL1 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 107 4e-22
UniRef50_Q985G9 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 106 5e-22
UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena... 106 5e-22
UniRef50_Q11C87 Cluster: Short-chain dehydrogenase/reductase SDR... 106 5e-22
UniRef50_A0L6T4 Cluster: Acetoacetyl-CoA reductase; n=24; Bacter... 106 5e-22
UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 106 5e-22
UniRef50_Q93HB3 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 106 6e-22
UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR... 106 6e-22
UniRef50_Q8YDW1 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 105 8e-22
UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_Q3W9J0 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 105 8e-22
UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 105 8e-22
UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogena... 105 8e-22
UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_A1UGS1 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_A0Z2D1 Cluster: Short-chain dehydrogenase/reductase (SD... 105 8e-22
UniRef50_Q9A514 Cluster: Oxidoreductase, short-chain dehydrogena... 105 1e-21
UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 105 1e-21
UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep... 105 1e-21
UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 105 1e-21
UniRef50_Q62JY9 Cluster: Acetoacetyl-CoA reductase; n=58; cellul... 105 1e-21
UniRef50_Q93QG6 Cluster: Short-chain dehydrogenase; n=1; Breviba... 105 1e-21
UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho... 105 1e-21
UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 105 1e-21
UniRef50_A3JIH3 Cluster: Acetoacetyl-CoA reductase; n=3; Gammapr... 105 1e-21
UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas... 105 1e-21
UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 105 1e-21
UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 105 1e-21
UniRef50_Q67RA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 105 1e-21
UniRef50_Q39N07 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 105 1e-21
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_Q3WH17 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_Q1M6K9 Cluster: Putative short-chain dehydrogenase/redu... 104 2e-21
UniRef50_Q0SJS1 Cluster: Short chain dehydrogenase/reductase; n=... 104 2e-21
UniRef50_A4TUX8 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_Q97DL2 Cluster: 3-oxoacyl-acyl carrier protein reductas... 104 3e-21
UniRef50_Q7W8W3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 104 3e-21
UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3... 104 3e-21
UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ... 104 3e-21
UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 104 3e-21
UniRef50_Q8TTF8 Cluster: Cyclohexanol dehydrogenase; n=1; Methan... 104 3e-21
UniRef50_Q73Q46 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 103 3e-21
UniRef50_Q72L28 Cluster: Gluconate 5-dehydrogenase; n=2; Thermus... 103 3e-21
UniRef50_Q9EX74 Cluster: SDR-like enzyme; n=1; Rhodococcus eryth... 103 3e-21
UniRef50_Q6B355 Cluster: Probable 3-oxoacyl-acyl-carrier protein... 103 3e-21
UniRef50_A3U149 Cluster: Short chain dehydrogenase; n=2; Proteob... 103 3e-21
UniRef50_A0Z805 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 103 3e-21
UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR... 103 3e-21
UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici... 103 3e-21
UniRef50_A2QB60 Cluster: Catalytic activity: precursor; n=1; Asp... 103 3e-21
UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 103 3e-21
UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 103 4e-21
UniRef50_Q57A51 Cluster: Oxidoreductase, short-chain dehydrogena... 103 4e-21
UniRef50_Q3E250 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_Q0RVL6 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 103 4e-21
UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_A5ZC97 Cluster: Putative uncharacterized protein; n=3; ... 103 4e-21
UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 103 4e-21
UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 103 4e-21
UniRef50_Q11EK1 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_Q0SFL9 Cluster: Short chain dehydrogenase; n=1; Rhodoco... 103 6e-21
UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 102 8e-21
UniRef50_Q18QN3 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_A7NQP2 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_A7CX22 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 102 8e-21
UniRef50_A1B7W8 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_Q5V3M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 102 8e-21
UniRef50_Q46MP7 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_Q397M6 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_Q3BBM8 Cluster: Xylitol dehydrogenase; n=1; Pantoea ana... 102 1e-20
UniRef50_Q1M371 Cluster: Putative short-chain dehydrogenase/oxid... 102 1e-20
UniRef50_A4E7X7 Cluster: Putative uncharacterized protein; n=2; ... 102 1e-20
UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular... 102 1e-20
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 102 1e-20
UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 102 1e-20
UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep... 101 1e-20
UniRef50_Q28RW9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 101 1e-20
UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 101 1e-20
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 101 1e-20
UniRef50_A6W3U8 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_Q397Q8 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 101 2e-20
UniRef50_A3U137 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_A3PY16 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ... 101 2e-20
UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_O82465 Cluster: Short-chain alcohol dehydrogenase; n=11... 101 2e-20
UniRef50_Q2U0V0 Cluster: Dehydrogenases with different specifici... 101 2e-20
UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 101 2e-20
UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 101 2e-20
UniRef50_Q5YUD9 Cluster: Putative short chain dehydrogenase; n=1... 101 2e-20
UniRef50_Q3VYE5 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 101 2e-20
UniRef50_Q1GNJ8 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 101 2e-20
UniRef50_A7C291 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 101 2e-20
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_A3Q7F4 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q5KMV5 Cluster: Fatty acid beta-oxidation-related prote... 101 2e-20
UniRef50_Q4PDJ1 Cluster: Methionine aminopeptidase; n=17; cellul... 101 2e-20
UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo... 101 2e-20
UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 101 2e-20
UniRef50_Q2SC03 Cluster: Short-chain alcohol dehydrogenase-like ... 100 3e-20
UniRef50_Q13GR0 Cluster: Putative short-chain dehydrogenase/redu... 100 3e-20
UniRef50_Q08MV7 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 100 3e-20
UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20
UniRef50_A6VWC3 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20
UniRef50_A6D230 Cluster: Short-chain dehydrogenase; n=1; Vibrio ... 100 3e-20
UniRef50_A5FTT3 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20
UniRef50_A1K6W6 Cluster: Short-chain dehydrogenase family protei... 100 3e-20
UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20
UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20
UniRef50_A2YPN0 Cluster: Putative uncharacterized protein; n=3; ... 100 3e-20
UniRef50_Q9RPT1 Cluster: Rhamnolipids biosynthesis 3-oxoacyl-[ac... 100 3e-20
UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|R... 100 4e-20
UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 100 4e-20
UniRef50_Q2LXQ4 Cluster: 3-oxoacyl-reductase; n=1; Syntrophus ac... 100 4e-20
UniRef50_Q1LNQ8 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A5V1D1 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A4WBV5 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A1BC69 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A0YAE5 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 100 4e-20
UniRef50_A1CYI4 Cluster: Short chain dehydrogenase/reductase fam... 100 4e-20
UniRef50_Q9HLN6 Cluster: Probable glucose 1-dehydrogenase; n=4; ... 100 4e-20
UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R... 100 4e-20
UniRef50_A7D6X0 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_P73826 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 100 4e-20
UniRef50_Q8FV67 Cluster: 2-deoxy-d-gluconate 3-dehydrogenase, pu... 99 5e-20
UniRef50_Q7VZN8 Cluster: Short-chain dehydrogenase; n=3; Bordete... 99 5e-20
UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 99 5e-20
UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_Q390H0 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_Q1YPS9 Cluster: Putative uncharacterized protein; n=1; ... 99 5e-20
UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 99 5e-20
UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari... 99 5e-20
UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A5FZN0 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_Q4PLZ8 Cluster: Probable short chain dehydrogenase; n=1... 99 5e-20
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_Q98C97 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 100 7e-20
UniRef50_Q880U7 Cluster: Oxidoreductase, short chain dehydrogena... 100 7e-20
UniRef50_Q6UP79 Cluster: Putative oxidoreductase; n=1; Ralstonia... 100 7e-20
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 100 7e-20
UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 100 7e-20
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_Q0LZD3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 100 7e-20
UniRef50_Q0FUU8 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 100 7e-20
UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 100 7e-20
UniRef50_A5I7D8 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n... 100 7e-20
UniRef50_A1SHT3 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_A0GPK9 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=... 100 7e-20
UniRef50_Q8FWQ0 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 99 9e-20
UniRef50_Q83HQ5 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 99 9e-20
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_Q1MCI6 Cluster: Putative short-chain dehydrogenase/redu... 99 9e-20
UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 99 9e-20
UniRef50_Q0FPS1 Cluster: Probable dehydrogenase; n=1; Roseovariu... 99 9e-20
UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A3SL40 Cluster: Putative uncharacterized protein; n=1; ... 99 9e-20
UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A1TC74 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 99 9e-20
UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 99 9e-20
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 99 9e-20
UniRef50_Q51576 Cluster: Uncharacterized oxidoreductase PA3106; ... 99 9e-20
UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 99 9e-20
UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with dif... 99 1e-19
UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ... 99 1e-19
UniRef50_Q4JXS5 Cluster: Dehydrogenase related to short-chain al... 99 1e-19
UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19
UniRef50_Q11K25 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19
UniRef50_A7B102 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-19
UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-19
UniRef50_A3SDF7 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19
UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19
UniRef50_Q4J702 Cluster: Oxidoreductase; n=2; Sulfolobus|Rep: Ox... 99 1e-19
UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 98 2e-19
UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogena... 98 2e-19
UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 98 2e-19
UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_Q2G4C1 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_Q24Z94 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19
UniRef50_Q1NH53 Cluster: Short-chain alcohol dehydrogenase; n=2;... 98 2e-19
UniRef50_Q13I70 Cluster: Putative short-chain dehydrogenase/redu... 98 2e-19
UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena... 98 2e-19
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 98 2e-19
UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR... 98 2e-19
UniRef50_Q4P1P4 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19
UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 98 2e-19
UniRef50_P16543 Cluster: Granaticin polyketide synthase putative... 98 2e-19
UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 98 2e-19
UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 98 2e-19
UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc... 98 2e-19
UniRef50_Q3WFS5 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_Q3WAU6 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_Q0SJT0 Cluster: Short chain dehydrogenase; n=13; Actino... 98 2e-19
UniRef50_A7CWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_A4XEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_A4SZ40 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19
UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re... 98 2e-19
UniRef50_Q5KIP0 Cluster: Oxidoreductase, putative; n=2; Basidiom... 98 2e-19
UniRef50_Q1DXC7 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19
UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19
UniRef50_P55541 Cluster: Uncharacterized short-chain type dehydr... 98 2e-19
UniRef50_Q9EWT4 Cluster: Putative oxidoreductase; n=2; Streptomy... 97 3e-19
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 97 3e-19
UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19
UniRef50_Q9RLV7 Cluster: Diacetyl(Acetoin) reductase; n=4; Lacto... 97 3e-19
UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 97 3e-19
UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|... 97 3e-19
UniRef50_A5V529 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 97 3e-19
UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 97 3e-19
UniRef50_A1ZW13 Cluster: Glucose 1-dehydrogenase IV; n=2; Bacter... 97 3e-19
UniRef50_A1UD24 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19
UniRef50_A0Z8R8 Cluster: Putative uncharacterized protein; n=1; ... 97 3e-19
UniRef50_A0QPV0 Cluster: 2-hydroxycyclohexnecarboxyl-CoA dehydro... 97 3e-19
UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specifici... 97 4e-19
UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 97 4e-19
UniRef50_Q7NXT0 Cluster: Probable 3-oxoacyl-[acyl-carrier protei... 97 4e-19
UniRef50_Q2B7X3 Cluster: Oxidoreductase; n=8; Bacillus|Rep: Oxid... 97 4e-19
UniRef50_Q28Q24 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19
UniRef50_Q0SDF2 Cluster: Possible 2-hydroxycyclohexanecarboxyl-C... 97 4e-19
UniRef50_Q0S5W1 Cluster: Reductase; n=1; Rhodococcus sp. RHA1|Re... 97 4e-19
UniRef50_A6GFJ4 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 97 4e-19
UniRef50_A5CCL7 Cluster: 3-oxoacyl reductase; n=1; Orientia tsut... 97 4e-19
UniRef50_A4AAT7 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19
UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19
UniRef50_A1U9F9 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19
UniRef50_Q9HT49 Cluster: Probable short-chain dehydrogenase; n=5... 97 5e-19
UniRef50_Q62E80 Cluster: Acetoacetyl-CoA reductase; n=60; Proteo... 97 5e-19
UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19
UniRef50_A7CX21 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19
UniRef50_A5UU94 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19
UniRef50_A0JVW0 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19
UniRef50_Q869L6 Cluster: Similar to Lactococcus lactis (Subsp. l... 97 5e-19
>UniRef50_O18404 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2;
n=49; cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase type-2 - Drosophila melanogaster (Fruit
fly)
Length = 255
Score = 345 bits (847), Expect = 9e-94
Identities = 163/255 (63%), Positives = 193/255 (75%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVT 60
M K V+LVTGG+SGLG+ATAE L KQG V++ DLPS+KG AK LG+ VF PVDVT
Sbjct: 1 MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVT 60
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
SE DV ALQ DKFGRLD +NCAG A+A + +NF K L FQ I +N +GTF
Sbjct: 61 SEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTF 120
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
NVIRL+ GL+G N P+ DGQRGV++NTASVAAFDGQIGQAAYSASKA VVGMTLP+ARD+
Sbjct: 121 NVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDL 180
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPML 240
+ QGIR+ TIAPGLF TPM+ LPE L S+PFP RLG P E+A LVQ+I +NP+L
Sbjct: 181 STQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLL 240
Query: 241 NGETIRLDGSLRMQP 255
NGE IR+DG+LRM P
Sbjct: 241 NGEVIRIDGALRMMP 255
>UniRef50_Q99714 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2;
n=109; cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase type-2 - Homo sapiens (Human)
Length = 261
Score = 340 bits (835), Expect = 2e-92
Identities = 163/253 (64%), Positives = 195/253 (77%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
KGLVA++TGG+SGLG ATAE LV QG V+ DLP++ G+ AK LG N VFAP DVTSE
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
DV+ AL + KFGR+D +NCAG+A AS+ YN KK Q L FQ + VNL+GTFNV
Sbjct: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
IRL G +G+N PD GQRGV+INTASVAAF+GQ+GQAAYSASK G+VGMTLP+ARD+A
Sbjct: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNG 242
GIRV+TIAPGLF TP++ LPE L + VPFPSRLG P E+A LVQ+II+NP LNG
Sbjct: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNG 248
Query: 243 ETIRLDGSLRMQP 255
E IRLDG++RMQP
Sbjct: 249 EVIRLDGAIRMQP 261
>UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Oceanobacillus iheyensis
Length = 255
Score = 287 bits (704), Expect = 2e-76
Identities = 142/251 (56%), Positives = 182/251 (72%), Gaps = 2/251 (0%)
Query: 5 LVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDD 64
+ A+VTGG+SGLG+AT L QGG+V I DL G+ A LG+N + VDVT E
Sbjct: 6 MTAVVTGGASGLGEATVRRLHNQGGKVAIFDLNKENGERLATELGDNVDYFQVDVTDETS 65
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
V++AL +++ + A++NCAG+A A + K+ L F N I++NLIGTFNVIR
Sbjct: 66 VQKALDNVMEQSDGIHAVVNCAGIAIAEKTIG--KKGVHSLQHFSNVIEINLIGTFNVIR 123
Query: 125 LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
LA + N+P+ +G+RGV+INTASVAAF+GQIGQAAYSASK GV GMTLP+ARD++ G
Sbjct: 124 LAAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIARDLSTLG 183
Query: 185 IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGET 244
IRV+TIAPGLF TP+ E+LP+ A + L PFPSRLG P E+A L QSII+NPMLNGE
Sbjct: 184 IRVMTIAPGLFLTPLFEKLPDKAKEELGKMTPFPSRLGKPIEYAKLAQSIIENPMLNGEV 243
Query: 245 IRLDGSLRMQP 255
IRLDG++RMQP
Sbjct: 244 IRLDGAIRMQP 254
>UniRef50_Q128N5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=24; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 259
Score = 270 bits (662), Expect = 2e-71
Identities = 140/257 (54%), Positives = 180/257 (70%), Gaps = 8/257 (3%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQ----NTAKSLGEN-AVFAPVD 58
G V +VTGG+SGLG+ TA +LV G +VVI D+ + KG+ K LGE A F P D
Sbjct: 5 GKVFIVTGGASGLGEGTARMLVANGAKVVIADMQADKGEAIVSELTKELGEGKAAFVPCD 64
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ E D +A+ G+L L+NCAG+A A + K L +F TI VNLIG
Sbjct: 65 VSQEAD-GQAVVAKAVSMGKLMGLVNCAGIAPAEKTVG--KNGAHGLALFSKTITVNLIG 121
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
+FN+IRLA + KN P+A G+RGV+I+TASVAA+DGQIGQAAYSASK G+VGMTLP+AR
Sbjct: 122 SFNMIRLAADAMCKNEPEATGERGVLISTASVAAYDGQIGQAAYSASKGGIVGMTLPIAR 181
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP 238
D+A+ GIR +TIAPG+F TPM+ +P+ SL A VPFPSRLG PQ++A L + II+N
Sbjct: 182 DLARNGIRNMTIAPGIFGTPMLFSMPQEVQDSLAAGVPFPSRLGTPQDYAKLAKHIIEND 241
Query: 239 MLNGETIRLDGSLRMQP 255
MLNGE IRLDG++R+ P
Sbjct: 242 MLNGEVIRLDGAIRLAP 258
>UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=7; cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - gamma proteobacterium HTCC2207
Length = 257
Score = 264 bits (648), Expect = 1e-69
Identities = 125/251 (49%), Positives = 172/251 (68%), Gaps = 2/251 (0%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN-AVFAPVDVTSEDD 64
VA+VTG SGLG+A A+ LV G +VV+ D+ + G LGE+ A F +DV S D
Sbjct: 7 VAVVTGAGSGLGRAAAQALVDGGAKVVVIDMNAEAGNTAVAELGESQARFIQLDVASGSD 66
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
V+ A + L GR+D +NCAG+ A + N + P +L+ ++ I+VNLIGTFN+ R
Sbjct: 67 VEAAFETILADLGRVDICVNCAGIGIAEKTIN-RDGDPHNLDHYRKVIEVNLIGTFNISR 125
Query: 125 LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
A + +N PD ++G++INTAS+AAFDGQ+GQ AYSA+K G+VGMTLP+ARD+A QG
Sbjct: 126 CAAAAMARNEPDEKTEKGIIINTASIAAFDGQMGQVAYSATKGGIVGMTLPMARDLASQG 185
Query: 185 IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGET 244
IRV TIAPG+ TP+M +P+P + +++PFP RLG P EF LV +++N LNGET
Sbjct: 186 IRVNTIAPGVMATPLMMSMPQPVQDGIISNIPFPKRLGEPAEFGQLVVHMVENSYLNGET 245
Query: 245 IRLDGSLRMQP 255
+RLDG +RMQP
Sbjct: 246 VRLDGGVRMQP 256
>UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=18; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Arthrobacter sp.
(strain FB24)
Length = 263
Score = 256 bits (628), Expect = 3e-67
Identities = 139/262 (53%), Positives = 174/262 (66%), Gaps = 12/262 (4%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE-----NAVFAPV 57
KG VAL+TGG+SGLG ATA L G VV+ DLPS++G+ A L AVF P
Sbjct: 4 KGTVALITGGASGLGAATARRLFDAGASVVLVDLPSSRGEAFAAELNAASGAGTAVFVPA 63
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DVTSE+ V+ A+ + G L ++NCAG+A+ +V ++ L+ F IQ+NL+
Sbjct: 64 DVTSEEQVQAAVAAAV-ALGPLRIVVNCAGIATPGKVLG--RDGVLPLDTFSRVIQINLV 120
Query: 118 GTFNVIRLAVGLIGKNAP---DADG-QRGVVINTASVAAFDGQIGQAAYSASKAGVVGMT 173
GTFNVIRLA + P + G +RGV+INTASVAAFDGQIGQ AY+ASK V MT
Sbjct: 121 GTFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMT 180
Query: 174 LPLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQS 233
LP+AR++A+ IRVVTIAPG+F TPMM LP+ A SL VP PSRLG P E+A L
Sbjct: 181 LPIARELARSLIRVVTIAPGIFETPMMAGLPQEAQDSLGKQVPHPSRLGRPAEYASLAAH 240
Query: 234 IIQNPMLNGETIRLDGSLRMQP 255
I+ N MLNGETIRLDG++RM P
Sbjct: 241 IVDNAMLNGETIRLDGAIRMGP 262
>UniRef50_Q86JE3 Cluster: Similar to Oceanobacillus iheyensis.
3-hydroxyacyl-CoA dehydrogenase; n=2; Dictyostelium
discoideum|Rep: Similar to Oceanobacillus iheyensis.
3-hydroxyacyl-CoA dehydrogenase - Dictyostelium
discoideum (Slime mold)
Length = 264
Score = 252 bits (618), Expect = 5e-66
Identities = 133/258 (51%), Positives = 176/258 (68%), Gaps = 9/258 (3%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG-ENAVFAPVDVTSE 62
G +VTGG+SGLG T+ L G + I D+ G+ + LG + +F+ VD+T E
Sbjct: 5 GKTFVVTGGASGLGLETSRHLRSLGANIFIMDMNEENGRKVVEELGSDKTMFSSVDITLE 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
D VK +L+ L KF + +INCAGVA+A RV + Q L++F + VNLIGTFNV
Sbjct: 65 DSVKLSLEHCLKKFKEIHGVINCAGVAAAQRVIK-RDGQVHPLDLFTRVVMVNLIGTFNV 123
Query: 123 IRLAVGLI-GKNAPDA-DG-----QRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
IRL +I +N P + DG ++GV I TASVAAF+GQ+GQ+AYSASK+GVVGMTLP
Sbjct: 124 IRLVADIIHNQNQPSSKDGGEEEEEKGVFIMTASVAAFEGQVGQSAYSASKSGVVGMTLP 183
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
+AR+ A IR+ TIAPG F TPM+E LP+ AIKS+ S+PFPSR+G P+EFA L Q +I
Sbjct: 184 MAREFATLKIRINTIAPGTFETPMVEMLPQAAIKSINESIPFPSRMGKPKEFAFLCQHLI 243
Query: 236 QNPMLNGETIRLDGSLRM 253
+N +NGE IRLDG+LR+
Sbjct: 244 ENTYINGEVIRLDGALRL 261
>UniRef50_A7RVM1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 248 bits (606), Expect = 1e-64
Identities = 116/253 (45%), Positives = 176/253 (69%), Gaps = 2/253 (0%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVT 60
+ + +VAL+ GG+SG+G+ATA L++ G R VI DLPS++GQNTA+ G + F P V
Sbjct: 2 LLEKVVALIVGGASGIGRATAIRLIRAGARAVIVDLPSSEGQNTAQEFGSHCTFIPGHVD 61
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
SE ++K A+++ +K+G ++A IN A + + + + P L +F+ T+++N +GTF
Sbjct: 62 SESEIKAAIKVAKEKYGCVNASINTAALNTKELTLS-ESGCPHPLELFEETMKINAVGTF 120
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
NV RL + N PD +G+RGV++N +S+ +GQ G+ AY+A+K + MTLP+ARD+
Sbjct: 121 NVARLVAESMATNTPDQEGERGVIVNVSSIHGTEGQSGKVAYAATKGAINAMTLPMARDL 180
Query: 181 AKQGIRVVTIAPGLFRTPM-MEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPM 239
AK GIRV TI+PG+F TPM M + + +++ SVPFP R G P+EFA LVQ++I+NPM
Sbjct: 181 AKLGIRVNTISPGIFNTPMFMAGRTKESREAITKSVPFPRRTGKPEEFAQLVQAVIENPM 240
Query: 240 LNGETIRLDGSLR 252
+NGE IR+DG+LR
Sbjct: 241 INGEIIRIDGALR 253
>UniRef50_A1W286 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=3; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Acidovorax sp.
(strain JS42)
Length = 255
Score = 245 bits (599), Expect = 1e-63
Identities = 126/253 (49%), Positives = 170/253 (67%), Gaps = 3/253 (1%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G+ ALVTGG SGLG+A+A L+++G VV DL +GQ + + DV+ E
Sbjct: 5 QGMTALVTGGVSGLGEASAVALLERGLNVVAVDLNDERGQAMEQQYAGRLRYVKADVSDE 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+++A+ + FG AL++CAG+ R+ K P L + N I+VN IGTFN
Sbjct: 65 GQMQQAIAAA-EAFGNFRALVHCAGIGGPVRLIE-KDGSPGSLEKYINIIRVNQIGTFNT 122
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+RLA + KN P DG+RGV + TASVA ++GQIGQ Y++SKAGV+GMT+ ARD+A
Sbjct: 123 LRLAAVAMAKNEP-IDGERGVCVLTASVAGYEGQIGQIPYASSKAGVIGMTIVAARDLAS 181
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNG 242
+ IRV TIAPGLF TP++ +LPE +SL ASVP P+RLGHP E+AL I++NPMLNG
Sbjct: 182 KFIRVCTIAPGLFDTPILAKLPEAVRQSLAASVPHPARLGHPSEYALTALHILENPMLNG 241
Query: 243 ETIRLDGSLRMQP 255
ETIRLDG++RM P
Sbjct: 242 ETIRLDGAIRMAP 254
>UniRef50_Q128L4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=58; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 261
Score = 244 bits (596), Expect = 2e-63
Identities = 128/258 (49%), Positives = 163/258 (63%), Gaps = 6/258 (2%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE-----NAVFAPV 57
+G ALVTG SGLG+ATA L + G +V + D+ A + +A+
Sbjct: 4 QGQAALVTGAGSGLGEATARELARLGAKVAVLDVNLANADKVAAEINAAHGDGSAIACQC 63
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
D+T + ++ A+ G L++ AG+ SA RV + + P L F + VNLI
Sbjct: 64 DITDTESLQAAIAKATAAHGTARILMSIAGIGSAKRVVS-RDGSPAPLEDFVRVVNVNLI 122
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
GT+NV RL K AP DG+RGV++ TASVAAFDGQ+GQ AYSASK+GVVGMTLP+A
Sbjct: 123 GTYNVARLFAAECAKLAPQEDGERGVMVFTASVAAFDGQVGQQAYSASKSGVVGMTLPMA 182
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
RD+A+ GIRV TIAPGLF TP+M LPEP +SL S+PFP RLG P+EFA L I+ N
Sbjct: 183 RDLAQHGIRVCTIAPGLFATPLMRTLPEPVQQSLADSIPFPPRLGKPEEFAQLASHIVTN 242
Query: 238 PMLNGETIRLDGSLRMQP 255
LNGE IRLDG+LRM P
Sbjct: 243 MHLNGEVIRLDGALRMAP 260
>UniRef50_A5V768 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=6; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Sphingomonas
wittichii RW1
Length = 259
Score = 241 bits (589), Expect = 2e-62
Identities = 126/258 (48%), Positives = 168/258 (65%), Gaps = 8/258 (3%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
KGL A+VTGG+SGLG ATA L +G +V + DL GQ A +G +F VDVTS+
Sbjct: 4 KGLTAVVTGGASGLGAATARALAARGAKVALFDLQQELGQAVAAEIG--GLFCAVDVTSD 61
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKE----QPFDLNIFQNTIQVNLIG 118
V G+ L+NCAG +A + + +E + + L++F IQ+NL+G
Sbjct: 62 ASVDAGFAQARAALGQERILVNCAGTGNAIKTASRSREDGSIRHYPLDVFDRIIQINLVG 121
Query: 119 TFNVI-RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
TF I + A G++ + P A G+RG ++NTASVAA DGQIGQ AYSASKAGVVG+TLP+A
Sbjct: 122 TFRCIAKSAAGMLAVD-PLASGERGAIVNTASVAAEDGQIGQVAYSASKAGVVGLTLPVA 180
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
RD+A GIRV TI PG+F TP++ P + +L ASVPFP RLG P+E+A L +I+N
Sbjct: 181 RDLAGDGIRVNTILPGIFETPLLMGQPTHVVDALGASVPFPKRLGRPEEYARLAIEMIEN 240
Query: 238 PMLNGETIRLDGSLRMQP 255
P NGE +RLDG++RM P
Sbjct: 241 PYFNGEDVRLDGAIRMAP 258
>UniRef50_Q28UN1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=21; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Jannaschia sp. (strain CCS1)
Length = 254
Score = 237 bits (580), Expect = 2e-61
Identities = 122/253 (48%), Positives = 166/253 (65%), Gaps = 5/253 (1%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G A+VTGG+SGLG+ATA L ++G V I D + + A +G + DVT +
Sbjct: 5 GQAAIVTGGASGLGEATARYLAERGCDVTILDFNGDRAREVAAEIGGYS--QQCDVTDPE 62
Query: 64 DVKEALQITLDKFGRLDAL-INCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
A+ + +FG+ + +NCAGV A+R+ +E L++F+ I+VNLIGT+NV
Sbjct: 63 HAATAVTSAMARFGQAPRICVNCAGVGLAARIVG--REGKTSLDVFRKVIEVNLIGTYNV 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ AV + P G+RGVVINTAS A DGQ+GQ+AY+ASK + M LPLAR++A+
Sbjct: 121 MTYAVQAMMDLPPLEGGERGVVINTASAAYQDGQVGQSAYAASKGAIAAMCLPLARELAR 180
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNG 242
GIRV IAPGLF TPMME LPE +++ A+VPFP+RLGHP EF +V SI++NP LNG
Sbjct: 181 PGIRVNAIAPGLFNTPMMESLPEETTQAIVANVPFPARLGHPAEFGQMVASIVENPYLNG 240
Query: 243 ETIRLDGSLRMQP 255
E IRLDG+ R+ P
Sbjct: 241 EVIRLDGATRLPP 253
>UniRef50_Q9ABU6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=13;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 260
Score = 235 bits (576), Expect = 6e-61
Identities = 125/256 (48%), Positives = 165/256 (64%), Gaps = 8/256 (3%)
Query: 5 LVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDD 64
+ A+VTGG+SGLG+ATA L QG +V + D+ +G AK +G VF V+VTS+ D
Sbjct: 7 VAAVVTGGASGLGEATARALAAQGVKVALFDMNEERGLQVAKEIG--GVFCKVNVTSDAD 64
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKE----QPFDLNIFQNTIQVNLIGTF 120
V + G+ L+NCAG +A++ + K + F L+ F IQ+NL+GTF
Sbjct: 65 VDAGFEKARAAHGQERILVNCAGTGNAAKTASRDKATGETKHFPLDAFDRIIQINLVGTF 124
Query: 121 NVI-RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
I + A G++ P DG+RG ++NTASVAA DGQ+GQAAYSASK GVVGMTLP+ARD
Sbjct: 125 RCIAKSAKGMLDLE-PLEDGERGAIVNTASVAAEDGQMGQAAYSASKGGVVGMTLPIARD 183
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPM 239
+ +GIRV TI PG+F TP+M PE L ASVPFP RLGHP+E+A L ++I
Sbjct: 184 LMGEGIRVNTILPGIFNTPLMNNAPEAVKAGLAASVPFPKRLGHPEEYAQLALTMITCGY 243
Query: 240 LNGETIRLDGSLRMQP 255
NGE +RLDG +RM P
Sbjct: 244 FNGEDVRLDGGIRMAP 259
>UniRef50_A1SNF3 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=4; Actinomycetales|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 262
Score = 226 bits (553), Expect = 4e-58
Identities = 126/256 (49%), Positives = 162/256 (63%), Gaps = 7/256 (2%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G A+VTGG+SG+G A A L ++G VV+ DL + KG+ A+ +G VFA VDVT D
Sbjct: 9 GASAIVTGGASGIGAAAARQLAEKGAVVVVADLQADKGEALAQEIG--GVFARVDVTDTD 66
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKE--QPFDLNIFQNTIQVNLIGTFN 121
++ A++ + L A +N AG+ A R E DL F+ I +NLIGTF+
Sbjct: 67 QIRAAVEAAA-QIAPLRACVNSAGIGWAQRTIGRDGEFDSAHDLEAFRKVIAINLIGTFD 125
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
++RLA + +N PD DG RG ++N ASVAAFDGQIGQA+YSASK GVVGMTLP+ARD++
Sbjct: 126 MVRLAATAMSRNEPDQDGCRGAIVNLASVAAFDGQIGQASYSASKGGVVGMTLPVARDLS 185
Query: 182 KQGIRVVTIAPGLFRTPMM-EQLPEPAIKS-LEASVPFPSRLGHPQEFALLVQSIIQNPM 239
GIR+ TIAPGL TP+ E A K+ L SV FP RLG P E A +V I N
Sbjct: 186 AAGIRLNTIAPGLIDTPIYGEGEAAEAFKAKLGESVLFPKRLGVPDELASMVVECITNSY 245
Query: 240 LNGETIRLDGSLRMQP 255
LN E IR+DG +RM P
Sbjct: 246 LNAEVIRVDGGIRMPP 261
>UniRef50_A0YH24 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
marine gamma proteobacterium HTCC2143|Rep:
3-hydroxyacyl-CoA dehydrogenase - marine gamma
proteobacterium HTCC2143
Length = 266
Score = 220 bits (538), Expect = 2e-56
Identities = 111/259 (42%), Positives = 164/259 (63%), Gaps = 9/259 (3%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG-ENAVFAPVDVTSEDD 64
+A+VTGGSSG+GKAT +VK+GG+ I D+ KGQ + LG +N ++ V+V
Sbjct: 7 IAVVTGGSSGMGKATIRRVVKEGGKAAIFDINDEKGQALVEELGADNVIYCHVNVMETAS 66
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
++ + +D+FG + N AG ++ P ++ ++ T+ +NL+GTF+V R
Sbjct: 67 IEAGIAKAMDRFGAIHICCNFAGGGIGGAARTMGRDGPHNIENYKKTVMLNLVGTFDVTR 126
Query: 125 LAVGLIGKNAP-DADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
L + KN P D RGV+INTASVA ++GQIGQAAY+++KAG++GMT+P+ARD+A
Sbjct: 127 LCAEQMSKNVPFDKYSGRGVIINTASVAGYEGQIGQAAYASAKAGIIGMTVPVARDLAVL 186
Query: 184 GIRVVTIAPGLFRTPMM-----EQLP--EPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
GIRV TI PGL TPM+ E P E ++ L + V +P RLG E A L Q +++
Sbjct: 187 GIRVNTIVPGLIATPMLLRGAEEMTPEIEQRLQPLSSQVLYPKRLGLADEIASLAQHMME 246
Query: 237 NPMLNGETIRLDGSLRMQP 255
N +NGE++R+DG +RMQP
Sbjct: 247 NDYINGESVRMDGGIRMQP 265
>UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to
3-hydroxyacyl-CoA dehydrogenase type-2
(3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH)
(3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (Scully
protein); n=1; Apis mellifera|Rep: PREDICTED: similar to
3-hydroxyacyl-CoA dehydrogenase type-2
(3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH)
(3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (Scully
protein) - Apis mellifera
Length = 265
Score = 206 bits (502), Expect = 6e-52
Identities = 104/249 (41%), Positives = 157/249 (63%), Gaps = 3/249 (1%)
Query: 5 LVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDD 64
+VA VTGG++G+GKA AE + +QGG+VV+ D+ S G +++G+ A+F DV E D
Sbjct: 6 IVAYVTGGANGIGKACAEKIFQQGGKVVVADI-SCNGAKVVENMGDKAIFTCTDVRLEKD 64
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
V ++++ +KFG ++ LIN AGV + + K ++P +++++ + N+ G FNV R
Sbjct: 65 VVDSIKCVKEKFGGVNVLINSAGVIGYETIIDHKTKKPHSVDMYRCIMDTNVWGVFNVTR 124
Query: 125 LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
L L+ +N PD + QRGV+IN +S+ A+D G Y ASKA V GMT+PLAR +A +G
Sbjct: 125 LLAPLMAENKPDENKQRGVIINLSSMMAYDPPAGLVTYGASKAAVSGMTMPLARGLAMKG 184
Query: 185 IRVVTIAPGLFRTPM-MEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGE 243
IRV+TI PG +PM Q P K + + P R G +E A L+Q+ I+NP++NGE
Sbjct: 185 IRVLTICPGYIDSPMTAPQKPPERAKWIRMKLT-PKRFGTCEEVAHLIQACIENPLINGE 243
Query: 244 TIRLDGSLR 252
IR+D R
Sbjct: 244 NIRIDMGFR 252
>UniRef50_A0GPG2 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Burkholderia phytofirmans PsJN|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Burkholderia phytofirmans PsJN
Length = 248
Score = 204 bits (498), Expect = 2e-51
Identities = 112/247 (45%), Positives = 155/247 (62%), Gaps = 5/247 (2%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
VA+VTG +SGLG AT + L G VV DL + ++LG + VDV++E V
Sbjct: 7 VAIVTGAASGLGLATCKGLAAAGAMVVGFDLDQAR---LDEALGADMQGLAVDVSNESSV 63
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
K + + GR+ +NCAG+ + + K Q F +++ + VNL GTFNVIR
Sbjct: 64 KSGIDAVVAMHGRVHVAVNCAGILGPCKTLS--KGQLFPSDLWNRVLGVNLTGTFNVIRH 121
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
A ++ N P+ G+RGV+INT+S AA GQ+GQAAYSASKAGV+GMTLP+ARD+A+ GI
Sbjct: 122 AALVMSANDPEETGERGVIINTSSGAARAGQMGQAAYSASKAGVIGMTLPIARDLAEHGI 181
Query: 186 RVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGETI 245
RVV+IAPGLF + M +P+ SL + FP R+G +EFA LV+ I++N LN TI
Sbjct: 182 RVVSIAPGLFESGMSAGMPQKVSDSLIEKMLFPRRMGKAEEFAGLVRHIVENAYLNAMTI 241
Query: 246 RLDGSLR 252
+D +R
Sbjct: 242 DIDCGMR 248
>UniRef50_Q1B5D1 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=16; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Mycobacterium
sp. (strain MCS)
Length = 272
Score = 202 bits (492), Expect = 9e-51
Identities = 113/253 (44%), Positives = 147/253 (58%), Gaps = 5/253 (1%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G A+V GG+ GLG+AT L G +VV+ DL KG K LG + D TSE+
Sbjct: 23 GSSAIVVGGAGGLGEATVRRLQGAGAKVVVADLADEKGAALEKELGVR--YVRTDATSEE 80
Query: 64 DVKEALQITLDKFGRLDALINC-AGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
V A+ + G L ++ G AS R+ K P DL+ F+ TI+ L FNV
Sbjct: 81 SVNAAIA-EAESMGPLRISVDTHGGPASGGRLIG-KDGSPLDLDGFKKTIEFYLTAVFNV 138
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+RL I K+ P +G RGV++NTAS+A ++GQIGQ YSA+K GV+GMTL ARD++
Sbjct: 139 MRLTAAAIAKSEPLEEGGRGVIVNTASIAGYEGQIGQLPYSAAKGGVLGMTLVAARDLSP 198
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNG 242
GIRV TIAPG TP + + + VPFP R+G E+A L QSII+N LNG
Sbjct: 199 LGIRVCTIAPGTINTPAYGKAADQLEQYWGPQVPFPKRMGRSTEYAQLAQSIIENDYLNG 258
Query: 243 ETIRLDGSLRMQP 255
E IRLDG+LR P
Sbjct: 259 EIIRLDGALRFPP 271
>UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;
n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
FadB2x - Pseudomonas stutzeri (strain A1501)
Length = 258
Score = 194 bits (473), Expect = 2e-48
Identities = 106/251 (42%), Positives = 151/251 (60%), Gaps = 3/251 (1%)
Query: 6 VALVTGGSSGLGKATAELLV-KQGGRVVICDLPSTKGQNTAKSLG-ENAVFAPVDVTSED 63
V ++TGG+SGLG ATA L ++G R+ I DL G+ +LG E A+F DV+SE+
Sbjct: 7 VVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTERAMFVATDVSSEE 66
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
V+ A+ + FG + IN A V + ++ K+ + L F +NL G FNV+
Sbjct: 67 SVQNAVDAVMANFGAIHVCINGAAVPTGFKILG-KEGKAAPLARFAQATAINLNGVFNVM 125
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ KN +A +RGVVIN +S AA++GQ+GQ AYSA+KAGV+G+ +P AR++
Sbjct: 126 SKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAARELGAI 185
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGE 243
G+RV IAPGLF T M+ L E + SL+ + P RLG +EFA II+N +N E
Sbjct: 186 GVRVNAIAPGLFLTTMVAALDEKVLGSLKEQMEAPKRLGDTREFAHCCAFIIENAYINAE 245
Query: 244 TIRLDGSLRMQ 254
TIRLD + RM+
Sbjct: 246 TIRLDAASRMR 256
>UniRef50_Q1GUS0 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=11; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 264
Score = 186 bits (453), Expect = 5e-46
Identities = 104/259 (40%), Positives = 154/259 (59%), Gaps = 10/259 (3%)
Query: 5 LVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDD 64
+ A+VTGG+SGLG+A+AE L + G +V I D+ G+ A+++G +F VD+TSED
Sbjct: 7 IAAVVTGGASGLGRASAEALAQSGVKVAIFDVNEEGGRAVAEAIG--GIFCKVDITSEDS 64
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQP----FDLNIFQNTIQVNLIGTF 120
V + G+ L++CA ++ + + K + + + Q LI ++
Sbjct: 65 VVAGYEAARAAHGQERILVHCAQISKGGKTVRYDKASGGYVRYSTEDYAFSAQGILIASY 124
Query: 121 NVIRLA-VGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+ LA +G+ + + DG+RG +I TAS AA D QIGQ Y + KAGV G+ LP+ARD
Sbjct: 125 RLASLAALGMANADPLNDDGERGTIILTASAAAQDAQIGQVGYGSLKAGVNGLVLPMARD 184
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPE--PAI-KSLEASVPFPSRLGHPQEFALLVQSIIQ 236
+ GIRV +I PG+F TP M + + PAI + L ASVPFP RLG P+EF LV + +
Sbjct: 185 LMDLGIRVNSIMPGIFATPPMLAVKDRAPAIFEGLAASVPFPKRLGKPEEFGSLVLELAR 244
Query: 237 NPMLNGETIRLDGSLRMQP 255
N NG+ +RLDG++RM P
Sbjct: 245 NSYFNGQNLRLDGAIRMPP 263
>UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=3;
Oligohymenophorea|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Tetrahymena
thermophila SB210
Length = 260
Score = 184 bits (448), Expect = 2e-45
Identities = 100/252 (39%), Positives = 149/252 (59%), Gaps = 4/252 (1%)
Query: 5 LVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAV-FAPVDVTSED 63
+VALVTGG+SGLG+AT L+++G RV I D KG G++ F DV+ E
Sbjct: 7 IVALVTGGTSGLGEATVYALLEKGVRVFIADRNEEKGLQIQTKYGQDRCRFQKCDVSDEA 66
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFK-KEQPFDLNIFQNTIQVNLIGTFNV 122
VK + + FG + L+N AGV SA + K ++Q + VN++GTFNV
Sbjct: 67 QVKALVDACVATFGAIHILLNSAGVISAGLIVGGKNQDQTIKTEEMNRVLGVNVVGTFNV 126
Query: 123 IR-LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ +A+ ++ + + +RGV++N ASVA +GQ GQ Y+ASK ++GMTLPLARD+
Sbjct: 127 TKYVALQMVKQQPLNEFKERGVIVNVASVAGIEGQRGQTVYAASKGAIIGMTLPLARDLG 186
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLN 241
K G+RV TIAPG+F+TPM + + I++L + R+G+P EFA + + N +
Sbjct: 187 KFGVRVCTIAPGIFQTPMGAGMSDKIIEALSKASAL-GRVGNPTEFADAILGLATNSFVT 245
Query: 242 GETIRLDGSLRM 253
G RLDG +R+
Sbjct: 246 GSIFRLDGGIRL 257
>UniRef50_Q4P9D8 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 287
Score = 171 bits (417), Expect = 1e-41
Identities = 102/253 (40%), Positives = 142/253 (56%), Gaps = 15/253 (5%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG-----ENAVFAPV 57
KG V +TGG+SGLG AT L G V I D+ + + A +L + A V
Sbjct: 4 KGRVFYITGGASGLGAATVAHLHTLGAYVAIMDINYSAASSLAYTLNSGNANQRAAAFEV 63
Query: 58 DVTSEDDVKEALQI--TLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVN 115
DV SE V A+ +L ++ +NC GV A ++ + + PFDL F+ T+++N
Sbjct: 64 DVCSESAVASAIASCDSLWPSVQVGGCVNCGGVGMAGKIID-QSGTPFDLETFRKTVEIN 122
Query: 116 LIGTFNVIRLAVGLIGKNAP-------DADGQRGVVINTASVAAFDGQIGQAAYSASKAG 168
LIGTFNV RL + ++ P ++ GV+INTAS AA +GQ GQ +YSASK G
Sbjct: 123 LIGTFNVSRLTAARLVRDLPRPFPKPTESTEDLGVIINTASAAALEGQAGQCSYSASKGG 182
Query: 169 VVGMTLPLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA 228
V+ ++LP+ARD+A GIRV+T+ P LF TPMM QLP A + +P+R G P+EFA
Sbjct: 183 VLALSLPMARDLAWFGIRVMTLVPTLFETPMMTQLPGRARAKILTQCEYPARFGKPEEFA 242
Query: 229 LLVQSIIQNPMLN 241
L + P N
Sbjct: 243 LSTSQEGETPPTN 255
>UniRef50_Q93SJ3 Cluster: USC5-2p; n=1; Myxococcus xanthus|Rep:
USC5-2p - Myxococcus xanthus
Length = 443
Score = 166 bits (404), Expect = 4e-40
Identities = 89/186 (47%), Positives = 119/186 (63%), Gaps = 3/186 (1%)
Query: 30 RVVICDLPSTKGQNTAKSLG-ENAVFAPVDVTSEDDVKEALQITLDKFGRLDALINCAGV 88
R + DL KG LG + A + V+V+ E V A+ D G L+ +NCAG+
Sbjct: 32 RSALFDLNDDKGAAAVAGLGADKARYFNVNVSDEAAVTAAIDQAHDFLGGLNVAMNCAGI 91
Query: 89 ASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRLAVGLIGKNAPDADGQRGVVINTA 148
A RV KE P L FQ T+ VNL+G+FNV + A + N DG+RGV+INTA
Sbjct: 92 LGAGRVLG--KEGPMPLAGFQGTVMVNLVGSFNVAKAAANRMQHNEAGTDGERGVIINTA 149
Query: 149 SVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAI 208
S+AA++GQIGQAAY+ASK GVV MTLP+AR++++ GIRV TIAPG+F TPM++ +PE
Sbjct: 150 SIAAYEGQIGQAAYAASKGGVVSMTLPMARELSRFGIRVNTIAPGVFWTPMVDGMPEAVQ 209
Query: 209 KSLEAS 214
+S AS
Sbjct: 210 QSXXAS 215
>UniRef50_Q236S0 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=4; Tetrahymena
thermophila SB210|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Tetrahymena
thermophila SB210
Length = 256
Score = 151 bits (366), Expect = 2e-35
Identities = 87/249 (34%), Positives = 136/249 (54%), Gaps = 4/249 (1%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+ LVA +TG SSG G A+ L+++G + + D + + A + VF +DVT E
Sbjct: 5 QNLVAFITGASSGFGLEVAKDLLEKGCKCYLTDRDNIDPKFLASYPKDRVVFRNLDVTDE 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ +K+A++ +FG +DA++N AGV + Y ++ F +N++GTFNV
Sbjct: 65 EGIKKAIEDCAIQFGHIDAVLNSAGVNIPA--YLSIIDEKFSPTHVNKCFNINVVGTFNV 122
Query: 123 IRLAVGLIGKNAPDADGQRG-VVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ A + K A ++ V++N SVA+F+ G + Y ASK V MTLP++RD+
Sbjct: 123 SKYAALQMVKQQNQAQQKKDYVIVNVGSVASFNSNNGMSIYGASKGAVAAMTLPMSRDLG 182
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLN 241
+ GIRVV + PG+F TPM + PE K+ A R GHP EF+ Q I+++ +N
Sbjct: 183 RYGIRVVCMCPGVFDTPMGKSAPERLYKA-TAKGTCLGRHGHPSEFSNAFQGILESTFMN 241
Query: 242 GETIRLDGS 250
G LD S
Sbjct: 242 GNHFFLDSS 250
>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
reductase - Leptospira interrogans
Length = 254
Score = 149 bits (360), Expect = 9e-35
Identities = 91/253 (35%), Positives = 138/253 (54%), Gaps = 18/253 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA----KSLGENAVFAPVD 58
KG A+VTG + G+GK+TA L K G +VI DL + TA K G A+ +
Sbjct: 5 KGKNAVVTGAARGIGKSTALTLAKAGANLVIADLNEESSKATADEISKQTGVKAIGIGTN 64
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ D +A+Q +D+FG +D L+N AG+ + + KKEQ + I VNL G
Sbjct: 65 VSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQ------WDAVIAVNLTG 118
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
TFN + A+ + KN P+ G +IN +S+A +G IGQ YSASKAGV+G T +A
Sbjct: 119 TFNCTQAAIKFMMKN-PNG----GSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVAL 173
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ-- 236
+MA + +R IAPG T M + +PE ++ A++P R G P++ A + +
Sbjct: 174 EMASRKVRCNAIAPGFIATEMTDAIPEKIRTAMVAAIPL-KRAGQPEDIANTIAFLASDI 232
Query: 237 NPMLNGETIRLDG 249
+ + G+ I ++G
Sbjct: 233 SSFITGQVIEVNG 245
>UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase, putative; n=26; Gammaproteobacteria|Rep:
3-oxoacyl-(Acyl carrier protein) reductase, putative -
Idiomarina loihiensis
Length = 254
Score = 148 bits (358), Expect = 2e-34
Identities = 93/258 (36%), Positives = 136/258 (52%), Gaps = 14/258 (5%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPST---KGQNTAKSLGENAVFA-PVD 58
K V ++TGG+ GLG A AE +QG ++ + D+ + Q + LG V VD
Sbjct: 4 KDSVIVITGGAQGLGLAMAEDFARQGAKLALIDINGDVLGEAQEQCEKLGAAKVVGYEVD 63
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKK---EQPFDLNIFQNTIQVN 115
+T E+ V+ + +F +D L+N AG+ + FK +Q L FQ+ + VN
Sbjct: 64 ITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDVN 123
Query: 116 LIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
L GTF R A + K G++GV+IN +SVA G +GQ YSA+KAGVV MT+
Sbjct: 124 LTGTFLCGREAAAQMVKA-----GKKGVIINISSVARA-GNMGQTNYSATKAGVVAMTVT 177
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
AR++ + GIR IAPG TPM Q+ A+ + VP R G P E A + II
Sbjct: 178 WARELGRYGIRCGAIAPGFIETPMTAQMKPEAVDRALSMVPL-KRWGQPNEIAHSARYII 236
Query: 236 QNPMLNGETIRLDGSLRM 253
+N +G + +DG +R+
Sbjct: 237 ENDFFSGRVVEIDGGVRL 254
>UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=4; Leptospira|Rep: 3-oxoacyl-[acyl-carrier
protein] reductase - Leptospira interrogans
Length = 256
Score = 144 bits (348), Expect = 3e-33
Identities = 94/261 (36%), Positives = 139/261 (53%), Gaps = 18/261 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTK---GQNTAKSLGENAVFAPVDV 59
KG LVTG +SGLGKA AE K+G ++V+ D+ K + K+LG DV
Sbjct: 4 KGKTVLVTGSASGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKTLGTEVYSFKADV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKE-----QPFDLNIFQNTIQV 114
+ E+D ++ +Q + +FG LD I AG+ + KE L+ +Q+ I V
Sbjct: 64 SKEEDAEKLMQSAVKQFGSLDVAILNAGILRDGLLVKTDKETGKVISKMSLSNWQSVIDV 123
Query: 115 NLIGTFNVIR-LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMT 173
NL G F R A+ +I + +GV+I ASVA G GQ YSA+KAGV MT
Sbjct: 124 NLTGVFLTGREAAIQMIESKS------KGVIIPIASVA-MHGNPGQTNYSAAKAGVASMT 176
Query: 174 LPLARDMAKQGIRVVTIAPGLFRTPM-MEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQ 232
A+++++ GIRV IAPG +T M M+ + A+K EA +P RLG P E AL
Sbjct: 177 KLWAKELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWEALIPI-GRLGEPYEIALSAD 235
Query: 233 SIIQNPMLNGETIRLDGSLRM 253
I+ N +++G + + G +++
Sbjct: 236 FIVSNDLVSGVILEISGGVKI 256
>UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=49; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella sp. (strain
ANA-3)
Length = 252
Score = 142 bits (344), Expect = 8e-33
Identities = 86/256 (33%), Positives = 136/256 (53%), Gaps = 12/256 (4%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFA--PVDVT 60
K V ++TGG+ GLG A A + G ++ + D+ K + LG +D+T
Sbjct: 4 KDKVVVITGGAGGLGLAMAHNFAQAGAKLALIDVDQEKLERACADLGSATEVQGYALDIT 63
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFD---LNIFQNTIQVNLI 117
E+DV L+ FG+++ L+N AG+ + K + D + FQ+ I VNL
Sbjct: 64 DEEDVVAGFAYILEDFGKINVLVNNAGILRDGMLVKAKDGKVTDRMSFDQFQSVINVNLT 123
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
GTF R A + ++ GQ GV++N +S+A G +GQ+ Y+ASKAGV M++ A
Sbjct: 124 GTFLCGREAAAAMIES-----GQAGVIVNISSLAKA-GNVGQSNYAASKAGVAAMSVGWA 177
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
+++A+ IR +APG+ T M + A++ LE VP RLG +E A V+ II+N
Sbjct: 178 KELARYNIRSAAVAPGVIATEMTAAMKPEALERLEKLVPV-GRLGQAEEIASTVRFIIEN 236
Query: 238 PMLNGETIRLDGSLRM 253
+NG +DG +R+
Sbjct: 237 DYVNGRVFEVDGGIRL 252
>UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Chromobacterium violaceum
Length = 246
Score = 141 bits (342), Expect = 1e-32
Identities = 82/256 (32%), Positives = 134/256 (52%), Gaps = 18/256 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDV 59
KG V+++TG +SG+GKATAE VK+G V +CDL + K+LG A VDV
Sbjct: 4 KGKVSIITGSASGIGKATAEKFVKEGAIVAVCDLNPDAVKTVVDELKALGGEAYGYKVDV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T + + E + ++ GR+D L+N AG+ +++ ++Q F I +NL G
Sbjct: 64 TDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQ------FDKVIDINLKGV 117
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+N R V + + GV++N +SV G GQ Y+A+K GV+G A++
Sbjct: 118 YNCARAVVDTMVEQGG------GVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAKE 171
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN-- 237
+ K+GIR + PG TP+++ +PE ++++E VP R+ P E A + + +
Sbjct: 172 LGKKGIRANAVCPGFVATPILKAMPEKVLQAMEDKVPM-RRMADPAEIANVYAFLASDEA 230
Query: 238 PMLNGETIRLDGSLRM 253
+NG I + G L +
Sbjct: 231 SYINGAAIEVTGGLTL 246
>UniRef50_A3FQ12 Cluster: Scully CG7113-PA, putative; n=2;
Cryptosporidium|Rep: Scully CG7113-PA, putative -
Cryptosporidium parvum Iowa II
Length = 284
Score = 141 bits (342), Expect = 1e-32
Identities = 94/258 (36%), Positives = 143/258 (55%), Gaps = 13/258 (5%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGR-VVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDD 64
V +VTGG SGLGKA E L+K+ R V + D +G+ + + + + VDVT +
Sbjct: 7 VIVVTGGMSGLGKAVVEELLKENPRKVCLMDAVLKEGELEEEPINKCEKYC-VDVTDYNC 65
Query: 65 VKEALQITLDKFGRLDALINCAGVASA-----SRVYNFK-KEQPFDL-NIFQNTIQVNLI 117
+K A + +DK+ ++DA+++CAG+ + N K E D+ I+ + VN+I
Sbjct: 66 IKSAAKSIIDKYSKIDAVVHCAGITHCPTPIVQKDDNGKIMENNEDIPEIWGKVVNVNVI 125
Query: 118 GTFNVIRLAVGLIGKNAPDADG-QRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
GT NVI + N ++ G ++GV I +S A DG Y ASK + +TLPL
Sbjct: 126 GTLNVIHCLSPFLAMNQGNSHGFEKGVFILVSSSTARDGPAQNQGYIASKGAINSLTLPL 185
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQ-LPEPAIKSLEASVPFPSRLGHPQEFALLVQSI- 234
AR++ GIRVVTI PG+F TPM + + E +L S+P R G P EFA V ++
Sbjct: 186 ARELGPLGIRVVTIGPGVFDTPMSKHAMSEKTSSTLLKSIPL-GRFGVPNEFAETVVNVG 244
Query: 235 IQNPMLNGETIRLDGSLR 252
+++ ++GE I LDG+ R
Sbjct: 245 LKSEYISGEIIYLDGAWR 262
>UniRef50_Q46PX5 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
NAD-dependent epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR - Ralstonia eutropha (strain
JMP134) (Alcaligenes eutrophus)
Length = 253
Score = 141 bits (341), Expect = 2e-32
Identities = 94/253 (37%), Positives = 137/253 (54%), Gaps = 19/253 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAV---FAPVDV 59
K VA+VTGG+SG+G+AT L QG VVI D S G+ A+ L E+++ ++ VDV
Sbjct: 9 KDKVAIVTGGASGIGEATVRLFASQGASVVIADR-SALGEKLARELSESSLAAHYSEVDV 67
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASR-VYNFKKEQPFDLNIFQNTIQVNLIG 118
+ EDD + + T+ +FGRLD ++ AG+A S V + EQ +Q I VNL G
Sbjct: 68 SREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQ------WQQMIDVNLTG 121
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
F +LA+ + K G G ++N AS+ G G A+Y+A+K GVV +T L
Sbjct: 122 VFLSNKLAIVQMKKQ-----GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLGV 176
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN- 237
A+ GIRV + PG TP++E+ E A L A+ P RLGH E A V + +
Sbjct: 177 SHAQDGIRVNAVCPGFVATPLIERATEEARARLVAAHPI-GRLGHADEVAKAVLFLASDD 235
Query: 238 -PMLNGETIRLDG 249
+ G ++ +DG
Sbjct: 236 ASFIVGTSLMVDG 248
>UniRef50_P66781 Cluster: Uncharacterized oxidoreductase
Rv1350/MT1393; n=19; Actinomycetales|Rep:
Uncharacterized oxidoreductase Rv1350/MT1393 -
Mycobacterium tuberculosis
Length = 247
Score = 140 bits (339), Expect = 3e-32
Identities = 86/224 (38%), Positives = 125/224 (55%), Gaps = 15/224 (6%)
Query: 7 ALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPV--DVTSEDD 64
A++TGG+ GLG A + V +G RVV+ D+ + AK LG + V V DVT DD
Sbjct: 10 AVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADD 69
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
V ++ +++FG LD ++N AG+ + + +EQ F I V+L GT+N R
Sbjct: 70 VDILIRTAVERFGGLDVMVNNAGITRDATMRTMTEEQ------FDQVIAVHLKGTWNGTR 123
Query: 125 LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
LA ++ + +RG ++N +SV+ G +GQ YSA+KAG+VGMT A+++A G
Sbjct: 124 LAAAIMRER------KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLG 177
Query: 185 IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA 228
IRV IAPGL R+ M E +P+ A VP R G P E A
Sbjct: 178 IRVNAIAPGLIRSAMTEAMPQRIWDQKLAEVPM-GRAGEPSEVA 220
>UniRef50_Q19246 Cluster: Dehydrogenases, short chain protein 25;
n=4; Caenorhabditis|Rep: Dehydrogenases, short chain
protein 25 - Caenorhabditis elegans
Length = 248
Score = 139 bits (336), Expect = 7e-32
Identities = 88/255 (34%), Positives = 137/255 (53%), Gaps = 18/255 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG---ENAVFAPVDVT 60
G +A+VTGG+SG+GKA ++ L K G RVV+ DL S TAK+L ++ FA DV+
Sbjct: 7 GRIAVVTGGASGIGKAISQTLAKHGARVVVADLDSGNAAATAKALPASQSHSSFA-CDVS 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+ D VK L + G L+NCAG+ S + K+EQ + + I+VNL G F
Sbjct: 66 NADSVK-GLSEHVKSLGTPSILVNCAGITKDSTLLKMKQEQ------WDSVIKVNLTGVF 118
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+V + V K + D + +IN +S+ G GQ Y+A+KAGV+G T A+++
Sbjct: 119 HVSQAFV----KASVDNNNHPLSIINVSSIVGKMGNFGQTNYAATKAGVIGFTKSAAKEL 174
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA--LLVQSIIQNP 238
AK+ +RV + PG +TPM E +P + + +P R+G +E A +L + +
Sbjct: 175 AKKNVRVNAVLPGFIKTPMTEAMPPTVLAEICKGIPM-GRMGEAEEIANSVLYLASDLSS 233
Query: 239 MLNGETIRLDGSLRM 253
+ G T+ + G M
Sbjct: 234 YVTGATLEVTGGFSM 248
>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=225; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
cholerae
Length = 244
Score = 137 bits (331), Expect = 3e-31
Identities = 85/254 (33%), Positives = 140/254 (55%), Gaps = 17/254 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VALVTG S G+GKA AELL ++G +V+ + Q + LG+N ++VT+
Sbjct: 4 EGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNP 63
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ ++ L+ D+FG +D L+N AG+ + + K+E+ D+ ++ NL F +
Sbjct: 64 ESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDI------METNLTSIFRL 117
Query: 123 IRLAV-GLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ + G++ K ++G +IN SV G GQA Y+A+KAGV+G T +AR++A
Sbjct: 118 SKAVLRGMMKK-------RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVA 170
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPM 239
+G+ V T+APG T M + L + + A VP RLG P+E A V + +
Sbjct: 171 SRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVP-AGRLGDPREIASAVAFLASPEAAY 229
Query: 240 LNGETIRLDGSLRM 253
+ GET+ ++G + M
Sbjct: 230 ITGETLHVNGGMYM 243
>UniRef50_Q8R9W0 Cluster: Dehydrogenases with different
specificities; n=4; Bacteria|Rep: Dehydrogenases with
different specificities - Thermoanaerobacter
tengcongensis
Length = 247
Score = 136 bits (328), Expect = 7e-31
Identities = 83/254 (32%), Positives = 137/254 (53%), Gaps = 19/254 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA----KSLGENAVFAPVDVTS 61
VA VTGGS G+G+A A L K G + I + K K G +A+ DV+
Sbjct: 7 VAFVTGGSRGIGRAIAVRLAKDGFNIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDVSK 66
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+V++A++ +++FG +D ++N AG+ + + ++E+ + I VNL G FN
Sbjct: 67 YHEVEKAVEKVIEEFGSIDVVVNNAGITKDNLILKMEEEE------WDQVIDVNLKGAFN 120
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
VI+ A + K ++G +IN +SV G +GQA Y+ASKAG++G+T +A+++A
Sbjct: 121 VIKFASKYMIKK------RKGKIINISSVVGLMGNVGQANYAASKAGIIGLTKSVAKELA 174
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ--NPM 239
+GI V +APG T M L E +++ S+P R G P+E A +V + +
Sbjct: 175 SRGITVNAVAPGFIETDMTNVLKEDIKEAMLKSIPL-KRAGKPEEVAEVVAFLASSASDY 233
Query: 240 LNGETIRLDGSLRM 253
+ G+ I +DG + M
Sbjct: 234 ITGQVINVDGGMVM 247
>UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas
naphthalenivorans (strain CJ2)
Length = 286
Score = 134 bits (325), Expect = 2e-30
Identities = 88/248 (35%), Positives = 132/248 (53%), Gaps = 9/248 (3%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
VA+VTG + G+G ATA+ L G RV + DL + Q A LG + DVTSE+ V
Sbjct: 21 VAIVTGAADGIGWATAQRLAADGLRVALLDLRADAAQARAAELGSIHLGLGCDVTSEESV 80
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ A+ L++FGR+DAL+N AG+ + + Q FD + V+L GTF + R
Sbjct: 81 EAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFD-----RVLAVHLRGTFLMSRA 135
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
+ + AP RG ++N S+A+ G + AYSA KAGV+GMT +A + A+ GI
Sbjct: 136 VARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMASEWARAGI 195
Query: 186 RVVTIAPGLFRTPMMEQLP-EPAIKSLEASVPFP-SRLGHPQEFALLVQSIIQN--PMLN 241
RV +APG RT ++ +L + AI + P R+ P E A ++ + + +
Sbjct: 196 RVNAVAPGYVRTALVAELERKGAIDAAAIRRRTPLGRMAEPAEIAEVIAFLASDRASYVT 255
Query: 242 GETIRLDG 249
G I +DG
Sbjct: 256 GALIPVDG 263
>UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3;
Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp.
SG-1
Length = 279
Score = 134 bits (324), Expect = 2e-30
Identities = 85/250 (34%), Positives = 132/250 (52%), Gaps = 18/250 (7%)
Query: 7 ALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDVTSED 63
A++TG SGLG++ A L K+G + + D+ G T K G NA+F DV+ +
Sbjct: 35 AIITGAGSGLGQSAAVRLAKEGIDIAVVDINEEGGNETVEMVKQKGVNAIFIKADVSKAE 94
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
+VK + T+++FG++D N AG+ S S Y E + + + +NL+G +
Sbjct: 95 EVKNYVDKTVEEFGKVDYFFNNAGI-SGSGQYFLNTE----IEEIEQVVSINLMGALYGV 149
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
R ++ KN G ++NTAS A GQ YSA+K G++G+T + + AK+
Sbjct: 150 RYVAEVMMKNGG------GSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSMVAEYAKE 203
Query: 184 GIRVVTIAPGLFRTPMMEQLPE--PAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PM 239
G+RV IAPG TPM++ E P +K+ RLG P+E A LV ++ +
Sbjct: 204 GLRVNAIAPGPTETPMVKAFYEANPEMKANATGGIPQKRLGTPEEVAELVTFLLTSKAEY 263
Query: 240 LNGETIRLDG 249
+NGE IR+DG
Sbjct: 264 INGEVIRIDG 273
>UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Bacillus halodurans
Length = 246
Score = 133 bits (322), Expect = 4e-30
Identities = 79/228 (34%), Positives = 125/228 (54%), Gaps = 16/228 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVT 60
G VA++TG G+G ATA+ ++G +V++CD+ + T + G A+ + VDVT
Sbjct: 5 GKVAMITGAGRGIGAATAKKFAREGAKVIVCDVREEEVAKTVAEIQDGGGEALGSVVDVT 64
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
DVK + +++F LD ++N AG+ + +++ N Q + + I VNL G F
Sbjct: 65 QRKDVKNVINQVIERFETLDVVVNNAGITADAQLTNMTDAQ------WDDVIDVNLKGVF 118
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
++ V I K + +RGV++N +SV G GQ Y+ASK GV GMT A+++
Sbjct: 119 -IVTQEVTTIMK-----EQKRGVILNASSVVGSYGNFGQTNYAASKWGVNGMTKTWAKEL 172
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA 228
+ IRV +APG TPM E++PE +K +E +RLG +E A
Sbjct: 173 GRYNIRVNAVAPGFILTPMTEKMPEKVLKVMEEKAVL-NRLGTVEEVA 219
>UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein)
reductase; n=2; unclassified Gammaproteobacteria
(miscellaneous)|Rep: 3-ketoacyl-(Acyl-carrier-protein)
reductase - marine gamma proteobacterium HTCC2080
Length = 248
Score = 132 bits (320), Expect = 6e-30
Identities = 88/246 (35%), Positives = 128/246 (52%), Gaps = 16/246 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
V L+TG S G+G A A +QG RVV+ + +TA LG A+ DV+
Sbjct: 10 VWLITGASRGIGAAIAARAHEQGCRVVVI-ARGEEAISTAGRLGLGAIAIQADVSDVAAA 68
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ A+ T+ FGR+D ++N AGV +V E +Q + VNL G N+IR
Sbjct: 69 QSAVDETIATFGRIDVVVNNAGVHRGGKVERLSPED------WQTVLNVNLTGALNMIRA 122
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
A +G + +IN +V F G G AY++SKAG+ GMT LA +MAKQGI
Sbjct: 123 AKPHMGSGSS--------IINIGAVVGFRGFPGDVAYASSKAGLSGMTNALAIEMAKQGI 174
Query: 186 RVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGETI 245
V + PGL T M L + A+ +++A +P RLG +E A +V + Q+ + G T+
Sbjct: 175 TVNLVIPGLVLTDMTSGLTDAAMDNMKAKIPM-GRLGQDREVAEVVYWVTQSRYMTGATV 233
Query: 246 RLDGSL 251
+DG L
Sbjct: 234 PVDGGL 239
>UniRef50_Q94G10 Cluster: CTA; n=3; Cucumis sativus|Rep: CTA -
Cucumis sativus (Cucumber)
Length = 271
Score = 131 bits (316), Expect = 2e-29
Identities = 75/202 (37%), Positives = 115/202 (56%), Gaps = 10/202 (4%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE-NAVFAPVDVTS 61
+G VA++TGG+ G+G+ TA+L K G +VVI D+ GQ K LG+ ++VF DVT
Sbjct: 14 EGKVAVITGGARGIGEQTAKLFFKHGAKVVIADIQDHLGQTLCKDLGQSSSVFVHCDVTK 73
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
E DV+ A+ + K+G+LD ++N AGV S ++ K+ P FQ + VNL+G
Sbjct: 74 EKDVETAVDTAVSKYGKLDIMLNNAGVFEESPNFDILKDDPL---TFQRVVNVNLVGASL 130
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
R A ++ RG ++ TAS+ + G IG AY++SK GV+G+ A D+
Sbjct: 131 GTRHAARVM------KPAGRGSIVTTASICSVIGGIGTHAYTSSKHGVLGLMRNAAVDLG 184
Query: 182 KQGIRVVTIAPGLFRTPMMEQL 203
+ GIRV ++P + T M +L
Sbjct: 185 RYGIRVNCVSPNVVPTEMGRKL 206
>UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Bacillus halodurans
Length = 246
Score = 130 bits (314), Expect = 3e-29
Identities = 87/259 (33%), Positives = 133/259 (51%), Gaps = 19/259 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPST-KGQNTA---KSLGENAVFAP 56
M +G A+VTG S G+G+ATA L + G VV+ + K + K LG A+
Sbjct: 1 MLQGKTAIVTGASRGIGRATAMELARHGANVVVNYAGNKEKAEKVVAEIKELGVEAIAIQ 60
Query: 57 VDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNL 116
DV + V+ ++ T+D FG +D L+N AG+ + ++ KE+ +D I NL
Sbjct: 61 ADVADSESVQAMVKETIDTFGAVDILVNNAGI-TRDNLFMRMKEEDWDA-----VIDTNL 114
Query: 117 IGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
G F+ + P + G +IN +SV G GQA Y A+KAGV+G+T L
Sbjct: 115 KGVFHCSKAVT------RPMMKQRFGRIINVSSVVGAIGNAGQANYVAAKAGVIGLTKTL 168
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
AR++A + I V +APG T M +LPE + +P +RLG P+E A V+ +
Sbjct: 169 ARELANRNITVNAVAPGFIETDMTGELPEDVKAQMLGQIPL-ARLGQPEEVAKAVRFLAS 227
Query: 237 N--PMLNGETIRLDGSLRM 253
+ L G+TI ++G + M
Sbjct: 228 DDASYLTGQTIHVNGGMVM 246
>UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Methanoculleus marisnigri
(strain ATCC 35101 / DSM 1498 / JR1)
Length = 249
Score = 130 bits (313), Expect = 4e-29
Identities = 84/249 (33%), Positives = 126/249 (50%), Gaps = 17/249 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQ---NTAKSLGENAVFAPVDVTSE 62
V ++TG +SG+G+A A+ + +GG+VV+ +G N K G +F DVT E
Sbjct: 8 VCVITGSTSGIGEACAKDMAAEGGKVVVSGRNEKEGARIVNEIKEAGGEVIFIRADVTVE 67
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
DDV+ + T++ FGRLD + +GV S + + E+ + + VNL G F
Sbjct: 68 DDVRNLVAKTVEAFGRLDVFVANSGVGSLGDPHEVETEE------WDRVLDVNLKGIFLC 121
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ AV + K GQ G ++NT S+ +F + G AY A+K GV +T L A
Sbjct: 122 DKYAVQQMLKQ-----GQGGAIVNTGSIHSFVAKQGVTAYGAAKGGVAMLTRTLGTSYAA 176
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLN- 241
QGIR +APG TP++ LP A + L+ P RLG P E A V + + N
Sbjct: 177 QGIRANFVAPGYIDTPLLAALPREAYEELKKLHPI-GRLGRPMEVAKAVTFLASDDASNI 235
Query: 242 -GETIRLDG 249
G ++ +DG
Sbjct: 236 TGTSLLVDG 244
>UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 269
Score = 129 bits (312), Expect = 6e-29
Identities = 81/248 (32%), Positives = 123/248 (49%), Gaps = 10/248 (4%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VA+VTGG+ G+G+ATA LL +G VVI D+ + + A L A+ P+D+ E
Sbjct: 10 GKVAIVTGGAGGIGEATARLLTARGACVVIADIAFERAEALAADLA-GAIALPLDLEQEQ 68
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
V+ ++ T+ FGRLD L N A + + ++ T VN+ GT
Sbjct: 69 SVETLVERTVAHFGRLDVLHNNAALLGPEIAQADGDVERMGTALWDRTFAVNVRGTMIAC 128
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
R A+ P RG ++NT S A G + QAAYS+SKA V+ MT +A K
Sbjct: 129 RAAL-------PHLRETRGCIVNTVSNLALQGHLIQAAYSSSKAAVIQMTRAIAASHGKA 181
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLN-- 241
G+R +APG+ TP + + PA++ + RLG P++ A + + + N
Sbjct: 182 GVRCNAVAPGMTMTPALREAFPPALRQVVEDETLRDRLGDPRDIAEAIAFLASDAARNVT 241
Query: 242 GETIRLDG 249
G+ + DG
Sbjct: 242 GQVLVCDG 249
>UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Petrotoga mobilis SJ95
Length = 248
Score = 129 bits (311), Expect = 8e-29
Identities = 84/255 (32%), Positives = 135/255 (52%), Gaps = 20/255 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVV---ICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+A+VTGGS G+GK + +K+G V+ I + P + + + ++ D+T
Sbjct: 7 IAIVTGGSRGIGKEISRNFIKEGATVIAIAIDERPQIEENEKSDFPEDRFIYYQADITDF 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ + E + +K+ ++D L+N AG+A + + K+E F IQVNL GTF +
Sbjct: 67 NAISEIVTEIYNKYQKIDILVNNAGMAKDNFLVIMKEED------FDKVIQVNLKGTFVM 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ ++ K + G +I+ ASV +G IGQ YSA+KAG++GMT A+++
Sbjct: 121 TKAVAKIMRKQ------KFGNIISMASVVGIEGNIGQTNYSAAKAGIIGMTKSWAKELTM 174
Query: 183 QG--IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNP 238
+G IRV IAPG RT M E L E I+ + + RLG PQ+ A L + +
Sbjct: 175 KGENIRVNAIAPGFVRTGMTESLKEELIEYVVENTCL-KRLGEPQDIAKLAVFLASDDSS 233
Query: 239 MLNGETIRLDGSLRM 253
+ G+ IR+DG LR+
Sbjct: 234 FITGQVIRIDGGLRI 248
>UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
reductase; n=1; Bacillus sp. SG-1|Rep:
3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus
sp. SG-1
Length = 246
Score = 127 bits (306), Expect = 3e-28
Identities = 76/256 (29%), Positives = 131/256 (51%), Gaps = 18/256 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
K A++TG ++G+G A A+ ++G +V++ D KG A+ L G + VF VDV
Sbjct: 4 KNKTAVITGSANGIGLAAAKKFAQEGCKVIMADYDENKGAAEAEKLQEEGGDTVFYQVDV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+ + V L +G +D LIN AG+ + + +++ FQ + VNL G
Sbjct: 64 ANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDD------FQRVLDVNLTGV 117
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F+ + + + + +G +INTAS + G +GQ Y+ASKA V+GMT A++
Sbjct: 118 FHCTQALLPAL------INSGKGKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAKE 171
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEF--ALLVQSIIQN 237
+GI V +APG+ T M +P+ + A +P + G P++ A L + ++
Sbjct: 172 FGPKGINVNAVAPGVIETEMTASIPDKVKAQMNALIPL-GKFGKPEDAANAYLFLASDES 230
Query: 238 PMLNGETIRLDGSLRM 253
+NG +++DG + M
Sbjct: 231 DYVNGVVLQVDGGIMM 246
>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Leptospira interrogans
Length = 259
Score = 126 bits (305), Expect = 4e-28
Identities = 90/257 (35%), Positives = 131/257 (50%), Gaps = 21/257 (8%)
Query: 2 FKGLVALVTGGSS--GLGKATAELLVKQGGRVVICDLPSTK----GQNTAKSLGENAVFA 55
F+G VALVTG +S GLG+A A + K+GG +V+ DL + + AK G +
Sbjct: 9 FEGKVALVTGAASPRGLGRAIANTIAKEGGDIVLVDLNKEQIEQAAADVAKEFGVKTLGL 68
Query: 56 PVDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVN 115
+VT +D + +KFG+LD L+N AGV ++ EQ FD + VN
Sbjct: 69 SCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLK-DNLFIRMSEQEFDF-----VLDVN 122
Query: 116 LIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
L G F + + A L+ K + G ++N +SV+ GQ GQA YS+SKAGV+ +T
Sbjct: 123 LKGVFLMTKYASKLLLK------AESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKV 176
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFP-SRLGHPQEFALLVQSI 234
AR+ A + + V + PG +T M LPE K L P R G QE A V+
Sbjct: 177 AAREFAGRNVLVNAVCPGYVQTDMTASLPEEVQKKLTDPAFIPLRRPGTQQEIANAVKFF 236
Query: 235 I--QNPMLNGETIRLDG 249
+ Q+ + G +R+DG
Sbjct: 237 LSDQSNYITGTYLRVDG 253
>UniRef50_Q5P686 Cluster: Subunit of
2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH; n=4;
Proteobacteria|Rep: Subunit of
2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 248
Score = 126 bits (303), Expect = 7e-28
Identities = 85/226 (37%), Positives = 124/226 (54%), Gaps = 17/226 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKS---LGENAVFAPVDVTSE 62
VALVTG +SG+GK TA ++G VVI D+ + K + T LG + D++++
Sbjct: 7 VALVTGSASGMGKQTALRFAERGAAVVINDIDAEKVRTTVDEFSRLGHRVLGTVADISNK 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
V +Q T++ FGR+D L+N AG+ A + E +D+ T+ VNL GTF
Sbjct: 67 AAVDGMVQQTVEAFGRIDILVNNAGMERAGALRKLS-EADWDI-----TVDVNLKGTFLC 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ G + +N + G ++N AS A+ G GQ YS++KAGVVGMT LA ++ +
Sbjct: 121 TQAVHGHMVEN------KHGRIVNIAS-RAWLGGAGQTPYSSAKAGVVGMTRALAIELGR 173
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA 228
GI V +APGL TPM E+LPE L + P +LG P + A
Sbjct: 174 SGITVNCVAPGLIHTPMWEELPEKDRNFLLSRQP-TGKLGEPDDIA 218
>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
Oxidoreductase - Oceanobacillus iheyensis
Length = 244
Score = 125 bits (302), Expect = 1e-27
Identities = 82/254 (32%), Positives = 133/254 (52%), Gaps = 21/254 (8%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDVTSE 62
VA++TGG SG+G ATA+L +G ++++ D+ KG + KS G A+F DVT+E
Sbjct: 7 VAVITGGVSGIGAATAKLFASEGAKLILVDMNEEKGASIEAELKSQGSEAIFIKADVTNE 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ VK +D FG++D L N AG+ + K + ++ T++V+L G F V
Sbjct: 67 EQVKNIYTTAIDTFGKVDILFNNAGIGAV------KPTEELTYAEWRKTVEVDLDGVFLV 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ A+ K GV++NTAS+ + G G AAY+A+KAGVV +T L + A
Sbjct: 121 AQAAIKEFLKAGS------GVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGLEYAA 174
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEF--ALLVQSIIQNPML 240
+ IRV + PG T ++ A+ + + P +RLG +E A+L + + +
Sbjct: 175 RNIRVNALCPGFIDTAILGDSDREALIN---TTPM-NRLGKSEEMAKAVLFMASDDSSFM 230
Query: 241 NGETIRLDGSLRMQ 254
G ++ +DG Q
Sbjct: 231 TGNSLIVDGGYTAQ 244
>UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase;
n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein
reductase - Pseudoalteromonas haloplanktis (strain TAC
125)
Length = 247
Score = 125 bits (302), Expect = 1e-27
Identities = 83/252 (32%), Positives = 127/252 (50%), Gaps = 20/252 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENA----VFAPVDVTS 61
V LVTG G+G++ G V D+ + + L N V ++
Sbjct: 7 VVLVTGAGQGIGQSIVSYFATAGANVAAVDINADTLNASVNELNANVAGNIVAITANIAK 66
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
D V++A+ ++KFGRLDA+IN AGV S + E + I VNL GTF
Sbjct: 67 SDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEH------WDKVIAVNLTGTFL 120
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
R A ++ A G G +IN +S AA G+ G + Y ASKAGV+G+T +AR++A
Sbjct: 121 CCREAAKVM-----QAQGS-GCIINVSSTAALTGE-GPSHYCASKAGVMGLTRSMARELA 173
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPM 239
GIRV TI PG TPMM +PE + + A++P +R+G ++ A + + +
Sbjct: 174 PVGIRVNTIVPGPTNTPMMADIPEEWTQQMIAAIPL-ARMGEGEDIAKVASFLACDDSGF 232
Query: 240 LNGETIRLDGSL 251
+ G+ I ++G +
Sbjct: 233 ITGQNIAVNGGM 244
>UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
dehydrogenase/reductase SDR - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 251
Score = 125 bits (301), Expect = 1e-27
Identities = 87/259 (33%), Positives = 141/259 (54%), Gaps = 24/259 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
+G V +VTGG++G+G+A+A L ++G RVV+ D+ +G+ T + + G A+F DV
Sbjct: 4 EGKVCVVTGGATGIGEASALALAREGARVVVGDVNVEEGRKTVEDIKKEGGEALFVECDV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGV-ASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
+ E+ + ++ T+ FGR+D L N AG+ + V K E ++ T VN+ G
Sbjct: 64 SREEGARRLVEETVGAFGRIDVLFNNAGINITEGSVPEMKVED------WRRTFAVNVDG 117
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
F R A+ + KN G +INTAS ++F G G AAY ASK V+ +T +A
Sbjct: 118 IFWCSRYAIPEMRKNGG------GRIINTASPSSFVGWAGNAAYIASKGAVMSLTRAMAM 171
Query: 179 DMAKQGIRVVTIAPGLFRTPM----MEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSI 234
D AK+ IRV I PGL +P+ ++Q +P ++++ S+ R G+P++ A +V +
Sbjct: 172 DHAKENIRVNAIVPGLILSPLGLNWVQQQEDP--EAVKESIHPIGRPGYPEDVAPVVVFL 229
Query: 235 IQN--PMLNGETIRLDGSL 251
Q+ G +DG L
Sbjct: 230 AQDDAEFATGAPFFMDGGL 248
>UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=2; Actinomycetales|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Mycobacterium avium (strain 104)
Length = 250
Score = 125 bits (301), Expect = 1e-27
Identities = 79/255 (30%), Positives = 123/255 (48%), Gaps = 19/255 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN---AVFAPVD 58
F VA+VTG +SG+G+ATA+ L + G +VV+ D+ G+ + E A F D
Sbjct: 3 FTSKVAVVTGAASGIGEATAKRLAEDGAKVVVADINEDGGERVVAEIAERGGEAAFLRTD 62
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
++ E+DV + + +G L N A VA + ++F + L G
Sbjct: 63 ISIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLH-----ELSTDVFDTVTGIGLRG 117
Query: 119 TFNVIRLAVG-LIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
TF +R + +IG G ++NTAS AA G AY A+K G+VG+T
Sbjct: 118 TFFCMRAEIAHMIGHGG-------GAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAG 170
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
D A+ GIRV +APG +TP M P+ E +P R+G P+E A +V ++ +
Sbjct: 171 LDYARNGIRVNAVAPGSIKTPQMASFPQEMQDEWERIIPM-GRMGRPEEVADVVAFLLSD 229
Query: 238 --PMLNGETIRLDGS 250
+ T+ +DG+
Sbjct: 230 AASFITATTVEIDGA 244
>UniRef50_Q9LW34 Cluster: Alcohol dehydrogenase-like protein; n=6;
Magnoliophyta|Rep: Alcohol dehydrogenase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 306
Score = 124 bits (300), Expect = 2e-27
Identities = 67/197 (34%), Positives = 110/197 (55%), Gaps = 9/197 (4%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VAL+TGG+SGLGKATA ++ G RVVI DL + G TAK LG A F DVT E
Sbjct: 42 EGKVALITGGASGLGKATASEFLRHGARVVIADLDAETGTKTAKELGSEAEFVRCDVTVE 101
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
D+ A+++T++++G+LD + N AG+ + + D+ F+ +++N+ G +
Sbjct: 102 ADIAGAVEMTVERYGKLDVMYNNAGIVGPMTPASISQ---LDMTEFERVMRINVFGVVSG 158
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
I+ A + + G ++ T+SVA G + +Y+ SK G+ A ++ +
Sbjct: 159 IKHAAKFM------IPARSGCILCTSSVAGVTGGLAPHSYTISKFTTPGIVKSAASELCE 212
Query: 183 QGIRVVTIAPGLFRTPM 199
G+R+ I+PG TP+
Sbjct: 213 HGVRINCISPGTVATPL 229
>UniRef50_A7RXH2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 256
Score = 124 bits (300), Expect = 2e-27
Identities = 87/262 (33%), Positives = 137/262 (52%), Gaps = 21/262 (8%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG------ENAVF 54
+ +G +ALVTGG SG+G+A E L +G V + DL + T+++L + F
Sbjct: 7 LLRGRLALVTGGGSGIGRAVCEALANRGASVSVIDLHGVGAKETSENLATHNDTTRHTHF 66
Query: 55 APVDVTSEDDVKEALQITLDKFGRLDA-LINCAGVASASRVYNFKKEQPFDLNIFQNTIQ 113
A V+V S +VK+ LQ ++ R L+N AG+A + + K EQ FD + I
Sbjct: 67 A-VNVASSSEVKDLLQAIHKEYQRAPCILVNSAGIAKDALLLKMK-EQDFD-----DVID 119
Query: 114 VNLIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMT 173
VNL GTF + + + +N + G +IN +S+ A G +GQA Y+ASKAGV G+T
Sbjct: 120 VNLKGTFLMCQTTAKAMVENKIN----NGSIINISSIVAKSGNMGQANYAASKAGVEGLT 175
Query: 174 LPLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQS 233
A ++A+ GIR I PG TPM ++P + ++ +P R G P A +V
Sbjct: 176 KVCAIELARFGIRCNAILPGFIDTPMTRKVPAHITEQIKHFIPL-GRFGQPSNIADVVSF 234
Query: 234 II--QNPMLNGETIRLDGSLRM 253
+ ++ + G +I + G L +
Sbjct: 235 LACDESSYITGASIDVTGGLSL 256
>UniRef50_A4L2T8 Cluster: FabG; n=24; Lactobacillales|Rep: FabG -
Lactobacillus reuteri
Length = 244
Score = 124 bits (298), Expect = 3e-27
Identities = 82/251 (32%), Positives = 128/251 (50%), Gaps = 20/251 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVIC----DLPSTKGQNTAKSLGENAVFAPVDVTS 61
V ++G + G+G ATA K G R+++ DLP T + LG + + D+ +
Sbjct: 7 VVFISGSTRGIGPATALEFAKAGSRLILNGRQDDLPKTFKEKL-DLLGADYHYLKGDIAN 65
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
E V E + ++D LIN AG+ + + K F I VNL GTF
Sbjct: 66 EKSVSELAAAAWKIYDKIDILINNAGITNDKLMMGMKASD------FDQVINVNLCGTFM 119
Query: 122 VIR-LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+ + + ++ K A G +IN AS+ G GQA Y+ASKAG++G+T +A++
Sbjct: 120 LTQPIFKKMLKKRA-------GCIINLASIVGLHGNTGQANYAASKAGIIGLTKSIAQEG 172
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPML 240
A++GIR IAPG+ + M E+L E L +P +RLG P+E A + + +N L
Sbjct: 173 ARRGIRCNAIAPGMIASDMTEKLSERVKDQLLNRIPL-NRLGQPEEVAKTAKFLAENDYL 231
Query: 241 NGETIRLDGSL 251
G+TI +DG +
Sbjct: 232 TGQTIVVDGGM 242
>UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1;
Leeuwenhoekiella blandensis MED217|Rep: Cyclohexanol
dehydrogenase - Leeuwenhoekiella blandensis MED217
Length = 261
Score = 124 bits (298), Expect = 3e-27
Identities = 89/261 (34%), Positives = 135/261 (51%), Gaps = 25/261 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE-NAVFA----PV 57
K V ++TG + GLG ATAELL K+G ++V+ D ++ + L E N A
Sbjct: 2 KDQVIIITGAAMGLGLATAELLAKEGAKLVLVDYNENALKDAEQKLKEINPEVALLSVKA 61
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+SE+ VK + T++KFGR+D L N AG+ +DL+IF+ I +NL+
Sbjct: 62 DVSSEEQVKNYVDKTVEKFGRIDGLYNNAGIEGKQASI-----VDYDLDIFKKVIDINLM 116
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G + +R + ++ K + G ++N ASV G + Q Y ASK V GMT A
Sbjct: 117 GVYYGLRYVIPVMQKQ------KFGRIVNVASVGGIRGVLNQMPYVASKHAVSGMTKNAA 170
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQL-----PE-PAIKSLEASVPFPSR-LGHPQEFALL 230
+ K GI IAPG TPM+ + PE P + + P+R LG P++ A +
Sbjct: 171 LEYGKDGILTNAIAPGAILTPMVAEAFKQVNPEDPKAAEAQYASNNPTRALGDPKDVASV 230
Query: 231 VQSIIQ--NPMLNGETIRLDG 249
V ++ N ++G+TI +DG
Sbjct: 231 VGFLLSKANGYVSGQTIAIDG 251
>UniRef50_Q5LDH2 Cluster: Putative
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase;
n=2; Bacteroidales|Rep: Putative
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Bacteroides fragilis (strain ATCC 25285 / NCTC 9343)
Length = 250
Score = 122 bits (295), Expect = 7e-27
Identities = 88/251 (35%), Positives = 130/251 (51%), Gaps = 18/251 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQ-NTAKSLGENAVFAPVDVTSEDD 64
VA+VTG S+G+G A+AE K G VV+ D+ K Q S G AV DV+
Sbjct: 8 VAMVTGASAGIGLASAEAFAKAGATVVLVDINEPKEQAGKLVSEGYKAVAYRCDVSDTRA 67
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
VKE + T+ +GRLDA +N AG+ + R ++ FD T+ V+L G +N +R
Sbjct: 68 VKEMIDWTVATYGRLDAALNNAGIQTPQRPMAEITDEEFD-----RTVAVDLKGVWNCMR 122
Query: 125 LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
+ + + G ++NT+S G GQAAY A K V+G+T A D + +G
Sbjct: 123 YEIIQMLQQGG------GAIVNTSSQGGVTGFPGQAAYIACKHAVIGLTRTAAIDYSAKG 176
Query: 185 IRVVTIAPGLFRTPMMEQL--PEPAI-KSLEASVPFPSRLGHPQEFALLVQSII--QNPM 239
IR+ + PG+ RTPM E+L P + K L +P RLG P+E A V + Q
Sbjct: 177 IRINAVCPGVIRTPMAEELIRRNPDLEKELVRDIP-AGRLGKPEEIANAVLWLCSSQASF 235
Query: 240 LNGETIRLDGS 250
++G + +DG+
Sbjct: 236 VDGYALLVDGA 246
>UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 258
Score = 122 bits (295), Expect = 7e-27
Identities = 86/254 (33%), Positives = 126/254 (49%), Gaps = 19/254 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VA+VTGG+ G+G AT L V +G VVI D+ +G+ A+ LG+ A F +DV E
Sbjct: 5 EGKVAIVTGGARGMGAATCRLFVAEGACVVIGDVLDAEGEALARELGDAARFMRLDVADE 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ T+++FGR+D L+N A V + + K F+ + +NL+GTF
Sbjct: 65 ANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRD------FERAVSINLVGTFVG 118
Query: 123 IRLAVGLIGKNAPDADGQR-GVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
IR AP Q+ G ++N +SV G AAY +SK GV G+T A ++
Sbjct: 119 IRTI-------APHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAALELG 171
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEP--AIKSLEASVPFPSRLGHPQEFALLVQSIIQN-- 237
QG+RV +I PG T M P I A+VP R+G P E A + +
Sbjct: 172 HQGVRVNSIHPGGVNTAMSNPTGAPLEEINKHYANVPL-QRVGLPDEIARATLFLASDDA 230
Query: 238 PMLNGETIRLDGSL 251
NG + +DG +
Sbjct: 231 SYCNGAELAVDGGM 244
>UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
dehydrogenase/reductase SDR - Caldivirga maquilingensis
IC-167
Length = 248
Score = 122 bits (295), Expect = 7e-27
Identities = 85/251 (33%), Positives = 123/251 (49%), Gaps = 18/251 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQ--NTAKSLGENAVFAPVDVTS 61
G VA+VTG G+G+ A L + G VV D+ + + + LG + +DVT
Sbjct: 6 GKVAIVTGAGQGIGRGIALRLARDGAIVVATDITGKENEVAEEVRKLGGQGMALRLDVTD 65
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+E + DK+G +D L+N AG+ Y FK N + I VNL G FN
Sbjct: 66 GKMAEEVARTVFDKYGHIDILVNNAGI------YPFKPFMEMTFNDWYRVINVNLNGVFN 119
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVA-AFDGQIGQAAYSASKAGVVGMTLPLARDM 180
V R V + K + G +IN AS+A A G +G YSASKAG+VG T LA ++
Sbjct: 120 VTRAVVPYMVKQ------KNGRIINIASIAGAVMGFMGLTHYSASKAGIVGFTRALALEL 173
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--P 238
A+ GI V IAPG TP E ++ + ++P +LG P++ A V + +
Sbjct: 174 ARYGITVNAIAPGAINTPGAATGSEEQVRMMINAIPM-GKLGTPEDIASAVAYLASDEAS 232
Query: 239 MLNGETIRLDG 249
+ G I +DG
Sbjct: 233 YITGALIVIDG 243
>UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Burkholderia sp. (strain 383) (Burkholderia
cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
Length = 251
Score = 122 bits (293), Expect = 1e-26
Identities = 88/254 (34%), Positives = 134/254 (52%), Gaps = 19/254 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VAL+TGG+ G G+A A V +G RVVI D+ GQ A LG+ A F +DVT E
Sbjct: 5 EGKVALITGGARGQGEAEARRFVAEGARVVIADVLDEAGQRVAAELGDAARFQHLDVTRE 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
D + A+ TL +FGRLD L+N A + + + L+ ++ I VN +G +
Sbjct: 65 ADWQIAVDATLAQFGRLDILVNNAAILKLVPI------EACSLDDYRKVIDVNQVGCWLG 118
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
++ A+G + A G G ++N +S A +G G +AY +SK V GMT A + +
Sbjct: 119 MKSALGAL----KAAGG--GSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAALEFGR 172
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPA---IKSLEASVPFPSRLGHPQEFALLVQSII--QN 237
GIRV ++ PG T +M + PE A S+ + +P +R+G P E A LV + ++
Sbjct: 173 YGIRVNSVHPGGIDT-VMARPPEFADFDPSSIYSGLPI-ARIGKPDEVASLVLFLASDES 230
Query: 238 PMLNGETIRLDGSL 251
G +DG +
Sbjct: 231 AYCTGSEFIVDGGM 244
>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Chloroflexus|Rep: Short-chain
dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
9485
Length = 256
Score = 121 bits (292), Expect = 2e-26
Identities = 84/261 (32%), Positives = 127/261 (48%), Gaps = 26/261 (9%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVD 58
F+G VA+VTGG+ G+G+ATA L ++G VVI D + + + G A+ D
Sbjct: 3 FQGKVAIVTGGAQGIGRATALALAREGAAVVIADRDAAATTALVEGINAWGGRALAVIAD 62
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ E D T+ +FG +D L+N AG+ + + L ++Q I VNL G
Sbjct: 63 VSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTI------ESTTLQLWQEIINVNLTG 116
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
F V R + + + G ++N ASV + G AAY+ASK GV+ +T +A
Sbjct: 117 VFLVSRFVMPELRRRGG------GAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMAL 170
Query: 179 DMAKQGIRVVTIAPGLFRTPMME--------QLPEPAIKSLEASVPFPSRLGHPQEFALL 230
D A GIRV + PGL T ++ Q P+ +++ VP RLG P+E A +
Sbjct: 171 DGAPDGIRVNCVCPGLIDTSLLRANAALVNTQRPDEELRAFARRVPL-GRLGTPEEVAAV 229
Query: 231 VQSIIQNP--MLNGETIRLDG 249
+ ++ L G I DG
Sbjct: 230 ILCLLSPTAGYLTGAVITADG 250
>UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member
10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR
family member 10 - Homo sapiens (Human)
Length = 270
Score = 121 bits (292), Expect = 2e-26
Identities = 80/230 (34%), Positives = 117/230 (50%), Gaps = 18/230 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTS 61
+ G V +VTGG G+G V G RVVICD + G+ + L AVF DVT
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVTQ 65
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
EDDVK + T+ +FGRLD ++N AG + + + F+ +++NL+GT+
Sbjct: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQ-----RPEETSAQGFRQLLELNLLGTYT 120
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ +LA+ + K+ +G VIN +S+ GQ Y A+K V MT LA D +
Sbjct: 121 LTKLALPYLRKS-------QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDES 173
Query: 182 KQGIRVVTIAPGLFRTPMMEQL----PEPAIKSLEASVPFP-SRLGHPQE 226
G+RV I+PG TP+ E+L P+P E + P R+G P E
Sbjct: 174 PYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAE 223
>UniRef50_Q7NFL8 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=36; Bacteria|Rep: 3-oxoacyl-[acyl-carrier
protein] reductase - Gloeobacter violaceus
Length = 248
Score = 121 bits (291), Expect = 2e-26
Identities = 84/260 (32%), Positives = 129/260 (49%), Gaps = 23/260 (8%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA----KSLGENAVFAP 56
+ G VALVTG G+G+A A L +G V + S + ++ G AV
Sbjct: 4 LLTGKVALVTGAGRGIGRACALALASEGAAVAVNYSRSEEAAQQVVAAIEAAGGQAVALK 63
Query: 57 VDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNL 116
DV + V+ L K+GRLDAL+N AG+ + E + + + +NL
Sbjct: 64 ADVADPEQVERLFADLLAKYGRLDALVNNAGITRDGLILRMSLED------WNDVVSLNL 117
Query: 117 IGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
GTF ++ A ++ K + G V+N +S + G GQA YSA+KAGV+G+T
Sbjct: 118 TGTFLCLKAASRIMLKQ------RSGRVVNISSTSGVAGNAGQANYSAAKAGVLGLTRSA 171
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
AR++ +GI V +APG T M L ++ + A VP R+G P+E A LV+ +
Sbjct: 172 ARELGSRGITVNAVAPGFIATDMTSAL---ELEPILAQVPL-RRVGQPEEVAGLVRFLCA 227
Query: 237 NP---MLNGETIRLDGSLRM 253
+P + G+ I +DG + M
Sbjct: 228 DPAAAYITGQVITIDGGMVM 247
>UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain
dehydrogenase/reductase SDR - Rhodopseudomonas palustris
(strain BisB5)
Length = 263
Score = 121 bits (291), Expect = 2e-26
Identities = 82/250 (32%), Positives = 130/250 (52%), Gaps = 19/250 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKS---LGENAVFAPVDVTSE 62
V LVTGG+SG+G+A A +QG V++ D+ G T ++ LG A + DVT E
Sbjct: 22 VVLVTGGASGIGRAAALAWARQGCSVLVADIDDRGGAETVEAIERLGSRARYQRNDVTDE 81
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASR-VYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+ ++ + FGRLD N AG+ S + N+ +++ I VNL+G FN
Sbjct: 82 RECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGAD------WRHVINVNLLGIFN 135
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
++ + L ++ G GV++NTASV G G +AY+A+K GV+G+T A +
Sbjct: 136 SMQPQLRLF-----ESQGA-GVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAALEYG 189
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ--NPM 239
+ GIR+ + PG TP++ +P+ I + + + RLG P E A LV +
Sbjct: 190 RSGIRINAVCPGYIETPLVAAVPD-RILTEKINRTGARRLGRPDEVAALVLWLASPAASY 248
Query: 240 LNGETIRLDG 249
+NG + +DG
Sbjct: 249 VNGAAVAVDG 258
>UniRef50_Q9W4U2 Cluster: CG3603-PA; n=8; Neoptera|Rep: CG3603-PA -
Drosophila melanogaster (Fruit fly)
Length = 249
Score = 121 bits (291), Expect = 2e-26
Identities = 82/253 (32%), Positives = 127/253 (50%), Gaps = 15/253 (5%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG-ENAVFAPVDVTSE 62
G VALVTG SG+G+AT LL + G +V+ D Q T + LG E + VDV+S
Sbjct: 8 GKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAALEVDVSSA 67
Query: 63 DDVKEALQITLDKFGRLDALI-NCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
V+ ++ L KF + ++ N AG+ + E+ +D + VNL GTF
Sbjct: 68 QSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMP-ERDYD-----DVYGVNLKGTF- 120
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
L K + + G ++N +S+ A +GQA Y+A+KAGV+ T +++
Sbjct: 121 ---LVTQAYAKAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFG 177
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPM 239
K GIRV I PG TPM+ +P+ + + P RLG P+E A ++ + Q+
Sbjct: 178 KFGIRVNCILPGYIDTPMVAVVPDSVKQEVVQRCPL-GRLGQPEEIAEVIAFLASPQSSY 236
Query: 240 LNGETIRLDGSLR 252
+NG I + G L+
Sbjct: 237 VNGAAIEVTGGLK 249
>UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR)
family protein; n=1; Thermobifida fusca YX|Rep:
Short-chain dehydrogenase/reductase (SDR) family protein
- Thermobifida fusca (strain YX)
Length = 282
Score = 120 bits (290), Expect = 3e-26
Identities = 72/197 (36%), Positives = 109/197 (55%), Gaps = 11/197 (5%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VA +TGG+SG+G+AT +G VVI D+ + G+ A LG+ AVF DV+ E
Sbjct: 6 RGRVAAITGGASGIGEATVRRFHTEGASVVIADIQAEAGRRLADELGDRAVFVRTDVSEE 65
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
DV + +D+FG+LD ++N AG+ A + + DL TI VNL G
Sbjct: 66 ADVAALVDTAVDRFGQLDIMVNNAGIMGALGPIDATRMSDADL-----TIAVNLRGVICG 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
++ A ++ + GV+I+T+S A G IG YSA K G++G++ +A ++ +
Sbjct: 121 MKHAARVMKPR------RSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVAAELRQ 174
Query: 183 QGIRVVTIAPGLFRTPM 199
GIRV TI PG +PM
Sbjct: 175 HGIRVNTIIPGSVVSPM 191
>UniRef50_Q0LZB7 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR precursor; n=2;
Alphaproteobacteria|Rep: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR precursor - Caulobacter sp.
K31
Length = 266
Score = 120 bits (290), Expect = 3e-26
Identities = 83/256 (32%), Positives = 124/256 (48%), Gaps = 10/256 (3%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G +A+VTGG+ G+G ATA L +G VI DL + Q A +G A D S
Sbjct: 5 EGKIAIVTGGAGGIGAATARRLTSEGATTVIADLDLERAQAVAAEIGHGATAFHYDAESV 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
D V+ + T+ +FGRLD L+N A + + + + + VNL G
Sbjct: 65 DTVEALVASTVARFGRLDILLNNAAITTPQIQREDTTAVDITFDTWDRVMAVNLRGYLAG 124
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ A+ + K G G +INTAS + G + + Y SKAGV+ +T +A +
Sbjct: 125 CKYAIPEMLK----VGG--GAIINTASGSGLVGDLSRIGYGTSKAGVIALTRFIATQYGR 178
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP--ML 240
QG+R +APGL T + I+ ++ V P RLG P++ A +V + +
Sbjct: 179 QGVRCNAVAPGLILTEASKAGVPELIEMIQNHVLTP-RLGKPEDVAAVVAFLASEDAGFI 237
Query: 241 NGETIRLD-GSLRMQP 255
NGETI + GSL QP
Sbjct: 238 NGETIVCNGGSLAHQP 253
>UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Roseiflexus sp. RS-1
Length = 246
Score = 120 bits (290), Expect = 3e-26
Identities = 79/255 (30%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKS---LGENAVFAPVDV 59
KG VA+VTG G+GKATA ++G V + D+ + T L A+ DV
Sbjct: 4 KGKVAIVTGAGHGIGKATAIAFAREGAHVAVVDINMAGAEATVAEITRLDGRALAVQADV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+ V+ ++ L GR+D L+N AG+ +R+ ++Q + I VNL G
Sbjct: 64 SQAASVESMVETVLAWGGRIDVLLNNAGITRDARLVKMTEQQ------WDAVINVNLKGV 117
Query: 120 FNVIRLAVGLIGKNAPDADGQ-RGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
+ R AP Q G +IN +S+ G GQ+ Y+A+K GV+ MT AR
Sbjct: 118 WLCARAV-------APHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR 170
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--Q 236
++ G+RV + PG T M+ +PE I+++ P RLG P+E A + + +
Sbjct: 171 ELGPSGVRVNAVTPGFIATEMITTIPEKVIQTVCERTPL-RRLGKPEEVAAVYVFLASDE 229
Query: 237 NPMLNGETIRLDGSL 251
+ + G I++DG L
Sbjct: 230 SSFMTGSVIQVDGGL 244
>UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Leeuwenhoekiella blandensis MED217
Length = 257
Score = 120 bits (289), Expect = 4e-26
Identities = 85/265 (32%), Positives = 132/265 (49%), Gaps = 25/265 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
K VA+VTGG+SGLGK++A+LL ++G ++V+ D+ G+ + + G A+F DV
Sbjct: 5 KNKVAIVTGGASGLGKSSAKLLAREGAKIVVSDIDEEGGKKVVQQIKEDGGEAIFIKQDV 64
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
ED+ K ++ TL+ +G+L L N AG+ V + L ++N I +NL GT
Sbjct: 65 AKEDEWKNVIETTLETYGKLHILANSAGIGLGGTV------EDVTLEDWKNLIDINLNGT 118
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F + G+ G D + G +IN +S+ G AY+ASK GV T A
Sbjct: 119 F--LGTKYGIKGMRKTD---EGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFTKSAALH 173
Query: 180 MAKQ--GIRVVTIAPGLFRTPMMEQL------PEPAIKSLEASVPFPSRLGHPQE--FAL 229
AKQ GIR+ +I P TPM+E E K LE+ P LG P + + +
Sbjct: 174 CAKQGYGIRINSIHPAYIWTPMVENFLKAQGDVEEGKKQLESLHPI-GHLGEPDDIGYGV 232
Query: 230 LVQSIIQNPMLNGETIRLDGSLRMQ 254
+ + ++ + G + +DG Q
Sbjct: 233 VYLASDESKFMTGSELVIDGGYTAQ 257
>UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=9; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 259
Score = 120 bits (289), Expect = 4e-26
Identities = 82/256 (32%), Positives = 130/256 (50%), Gaps = 17/256 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG--ENAVFAPVDVT 60
+G VA++TGG SG+G AT + V++G +VVI D+ +G + LG + A + VDVT
Sbjct: 6 QGRVAVITGGCSGIGLATVQRFVQEGAKVVIGDIDDARGHQLVEQLGGADVATYVHVDVT 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
S++ V Q D +G +D N AG++ DL+ ++ +VNL +
Sbjct: 66 SKEQVDALFQTAKDAYGSVDIAFNNAGISPPED----DSILDTDLDAWRKVQEVNLTSVY 121
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTAS-VAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+ A+ + + RG +INTAS VA Q +YSASK GV+ MT L
Sbjct: 122 LCCKAALPHMLEQG------RGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELGVQ 175
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQL-PEPAIKSLEASVPFP-SRLGHPQEF--ALLVQSII 235
A+QG+RV + PG TP++++L + A ++ V P R G P+E A+L +
Sbjct: 176 FARQGVRVNALCPGPVNTPLLQELFAKDAERAARRLVHVPMGRFGEPEEMASAVLFLASD 235
Query: 236 QNPMLNGETIRLDGSL 251
+ + T +DG +
Sbjct: 236 DSSFMTASTFLVDGGI 251
>UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Nocardioides sp. (strain BAA-499 / JS614)
Length = 253
Score = 120 bits (289), Expect = 4e-26
Identities = 85/231 (36%), Positives = 120/231 (51%), Gaps = 16/231 (6%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA--KSLGENAVFAPVDV 59
F G V L+TGG++G+G+ATA +QG RVV+ D+ + + G A+F DV
Sbjct: 7 FTGKVVLITGGATGIGRATALAFAQQGARVVVGDVDDRAAETVRLIEESGGTALFVRTDV 66
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
TS DV++ ++ T+D +G L N AG+ + + E FD TI V+L G
Sbjct: 67 TSAADVQQLVRTTVDTYGGLHVAFNNAGILPPTGPLAEQSEDDFD-----RTIAVDLKGV 121
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F ++ + ++ A G G +INTASVA G A Y A+K GVVG+T A D
Sbjct: 122 FLALKYEI----EHMAAAGG--GSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAAID 175
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPA--IKSLEASVPFPSRLGHPQEFA 228
A G+RV +APGL TPM + E A ++ AS F R P+E A
Sbjct: 176 YAAAGVRVNALAPGLVDTPMTKVWQEDAEIWDAVAASNGF-HRAAAPEEIA 225
>UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Burkholderia cenocepacia MC0-3|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Burkholderia cenocepacia MC0-3
Length = 277
Score = 120 bits (289), Expect = 4e-26
Identities = 83/254 (32%), Positives = 125/254 (49%), Gaps = 12/254 (4%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
KG +A+VTG +SG+G A A L +G VV+ DL Q + + G +AV A VD+
Sbjct: 5 KGKIAIVTGAASGIGAACAARLAHEGASVVVADLNLEGAQEQVRHIADSGGHAVAARVDI 64
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
E ++ +TL +G LD L N A S S + E D+ ++ +T+++NL GT
Sbjct: 65 GDECSIEALFDLTLKTWGGLDILHNNAAATSLSSTADAAIEA-IDVAVWDDTMRINLRGT 123
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
R A+ L+ G +INT+S AA G +G +AY KAG+ +T +A
Sbjct: 124 MLASRRALPLMRSRGG------GSIINTSSGAAQAGALGYSAYGVCKAGIENLTRYIAAQ 177
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN-- 237
K+GIR IAPGL TP+ + + S RLG P++ A V + +
Sbjct: 178 YGKEGIRCNAIAPGLIVTPVTRAYYAGELGEMMLSHHLTPRLGVPEDIAHAVVYLASDEA 237
Query: 238 PMLNGETIRLDGSL 251
+ G+ +DG L
Sbjct: 238 AFVTGQVFNVDGGL 251
>UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2;
Bacteria|Rep: Short chain dehydrogenase - Robiginitalea
biformata HTCC2501
Length = 251
Score = 120 bits (288), Expect = 5e-26
Identities = 80/246 (32%), Positives = 124/246 (50%), Gaps = 15/246 (6%)
Query: 7 ALVTGGSSGLGKATAELLVKQGGRVVICDL-PSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
AL+TG +SGLG A A L+ +G + + D P ++ G +A +DVT +V
Sbjct: 13 ALITGAASGLGLALARRLLNEGTHLGLIDHNPEGLTAEYRETAGRFKTYA-LDVTEPGEV 71
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
++A++ + G +D L+NCAG+ + + K D F + VN++G+FN +
Sbjct: 72 QKAVEDFAGQAGGIDILVNCAGITGRTGI----KSHEVDFGDFNRVLGVNVLGSFNTFKA 127
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
+ K G V++ AS+A DG G AYSA+KA V+GM ++ A+ GI
Sbjct: 128 VAPWMLKQGA------GRVLHVASIAGKDGNAGMLAYSAAKAAVIGMIKVQGKEYAESGI 181
Query: 186 RVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPMLNGE 243
+ IAP + RTP++E+ PE I+ + +P R G +EF II QN G
Sbjct: 182 LINGIAPAVIRTPILERQPEEQIRYMTDKIPM-KRCGTLEEFVEAACYIISDQNSFSTGF 240
Query: 244 TIRLDG 249
T L G
Sbjct: 241 TFDLSG 246
>UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia phymatum
STM815
Length = 249
Score = 119 bits (287), Expect = 6e-26
Identities = 83/229 (36%), Positives = 115/229 (50%), Gaps = 16/229 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL--GENAVFAPV--DVTS 61
VA+VTGG+ G+G+A A L + G R + DL + + A +L G N V V DVT
Sbjct: 7 VAVVTGGAGGIGRAIAARLQRDGLRAALWDLDARAAREAADALSNGRNDVVIGVHADVTD 66
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
E V AL TLD+FG L LIN AG L +Q I VNL F
Sbjct: 67 EASVAAALNTTLDRFGALHVLINSAGTTGP-----IATGADSALGAWQRCIDVNLRSVFL 121
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
R AV P D G ++N AS+A +G +AYSA+KAGV+ T + +++A
Sbjct: 122 CSRAAV------KPMLDAGFGRIVNLASIAGKEGNPSMSAYSAAKAGVIAFTKSMGKELA 175
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALL 230
+RV IAP + TP+++Q+ + A+ + A +P R G E A L
Sbjct: 176 LTPVRVNCIAPAVIETPLLQQMTDDALAASLAKIPM-QRAGTADEVANL 223
>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
TM_0325 - Thermotoga maritima
Length = 251
Score = 119 bits (287), Expect = 6e-26
Identities = 84/259 (32%), Positives = 132/259 (50%), Gaps = 26/259 (10%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVD 58
F+G V L+TG SG+GK A + ++G +V I D+ KG+ T KS+G A F D
Sbjct: 3 FQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIFGD 62
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V D ++ ++ T++ FGRLD L+N AG+ + +E F T+ VN+ G
Sbjct: 63 VAK--DAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEED------FDKTMAVNVKG 114
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
F + + AV + K GV++N +S A G + YS SKA ++G+T LA
Sbjct: 115 PFLLSKYAVEQMKKQGG------GVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAV 168
Query: 179 DMAKQGIRVVTIAPGLFRTP-MMEQL-----PEPAIKSLEASVPFPSRLGHPQE--FALL 230
D GIRV + PG ++ +M ++ PE +K + + +P RLG +E FA+L
Sbjct: 169 DYVDYGIRVNAVCPGTTQSEGLMARVKASPNPEELLKKMTSRIPM-KRLGKEEEIAFAIL 227
Query: 231 VQSIIQNPMLNGETIRLDG 249
+ + + G I +DG
Sbjct: 228 FAACDEAGFMTGSIINIDG 246
>UniRef50_Q1GRW4 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase
precursor; n=28; Proteobacteria|Rep:
3-oxoacyl-(Acyl-carrier-protein) reductase precursor -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 247
Score = 118 bits (285), Expect = 1e-25
Identities = 79/253 (31%), Positives = 125/253 (49%), Gaps = 16/253 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G+ ALVTG S G+G A A+ L QG R+ + + K +LG + V P D+
Sbjct: 6 GMTALVTGASGGIGSAIAQALAAQGARLAVSGSNADKLNAFRDTLGGDHVALPCDLGDAA 65
Query: 64 DVKEALQITLDKFG-RLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
V + ++ G +LD L+N AGV + + K E+ D+ I++NL F +
Sbjct: 66 AVDALVPAAVEALGGKLDILVNNAGVTRDNLIMRMKDEEWMDV------IRINLEANFRL 119
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
R A P + G +I+ SV G GQA Y+ASKAGV GMT LA+++A
Sbjct: 120 ARAAA------KPMMKARFGRIISITSVVGATGNPGQANYAASKAGVTGMTKALAQELAS 173
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPML 240
+G+ +APG T M + LP+ ++L +P R+G + A V + + +
Sbjct: 174 RGVTANCVAPGFIATAMTDDLPDAQKEALNQRIP-AGRMGEGSDIAAAVVYLASKEAAYV 232
Query: 241 NGETIRLDGSLRM 253
G+T+ ++G + M
Sbjct: 233 TGQTLHVNGGMAM 245
>UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain
dehydrogenase/reductase SDR - Parvibaculum
lavamentivorans DS-1
Length = 287
Score = 118 bits (285), Expect = 1e-25
Identities = 90/266 (33%), Positives = 130/266 (48%), Gaps = 27/266 (10%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VA++TGG+SG+G+ T +L +K+G +VV DL KG+ + LGEN + +V ED
Sbjct: 6 GKVAIITGGTSGIGRGTVDLFLKEGAKVVAADLQDHKGEAMERELGENFSYCRANVAHED 65
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
+VK + T+ KFG+LD L N AG + Q D+N F T+ V L G
Sbjct: 66 EVKNLVDHTVKKFGKLDILFNNAGYGGVG-----GELQEIDMNGFDETVGVLLKGVVLGY 120
Query: 124 RLAVGLIGKNAPDADGQR-GVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ AV P Q+ G +I+TASVA G YSA KA V + A ++A
Sbjct: 121 KYAV-------PHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAALELAP 173
Query: 183 QGIRVVTIAPG-----LF------RTPMMEQLPEPAIKSLEASVPFPSRLGHPQEF--AL 229
+R I PG +F T + +Q E L P P R G P++ A
Sbjct: 174 HFVRSNAICPGGIATSIFGSGLGLGTQVADQFAEVMKTHLAKIQPTP-RSGLPEDIANAA 232
Query: 230 LVQSIIQNPMLNGETIRLDGSLRMQP 255
L + ++ +NG+TI +DG+L P
Sbjct: 233 LFLASDESTFVNGQTIAVDGALTAGP 258
>UniRef50_Q53217 Cluster: Uncharacterized short-chain type
dehydrogenase/reductase y4vI; n=5; Proteobacteria|Rep:
Uncharacterized short-chain type dehydrogenase/reductase
y4vI - Rhizobium sp. (strain NGR234)
Length = 548
Score = 118 bits (285), Expect = 1e-25
Identities = 83/252 (32%), Positives = 128/252 (50%), Gaps = 21/252 (8%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G V +VTG + G+G+A ++ G VV DLP + ++LGE + VDV+ ED
Sbjct: 9 GRVIVVTGAAGGIGRALVDIFAANGDVVVAVDLPDSGVIELGQNLGEPHLGLEVDVSRED 68
Query: 64 DVKEALQITLDK-FGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
DV AL+ L+K F R++ L+N AG+ L FQ + +NL+G ++V
Sbjct: 69 DV-VALRALLEKRFSRIEVLVNNAGIGP-----TMAATADTALEDFQRALAINLVGAYSV 122
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
L+ A ++N AS+A G ++AY+ASKAG++ +T LA A
Sbjct: 123 ACETAKLMKPGA--------AIVNVASLAGLLGNPKRSAYAASKAGLISITKSLACRWAS 174
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPA---IKSLEASVPFPSRLGHPQEFALLVQSI--IQN 237
+GIRV +APG RTPM+ +L + ++ VP R+ P E A V+ + Q
Sbjct: 175 RGIRVTAVAPGHVRTPMVAELERAGKLDVSAIRRRVPL-GRIARPDEIARAVRFLASAQA 233
Query: 238 PMLNGETIRLDG 249
+ G T+ +DG
Sbjct: 234 SYITGSTLVVDG 245
Score = 76.2 bits (179), Expect = 8e-13
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 21/249 (8%)
Query: 8 LVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDVKE 67
+V GG++G+G A A + G VVI D + A LG+ + VD T E +V
Sbjct: 281 IVMGGATGVGAAIARRFAENGDTVVIADGDGEEAVKLAGLLGDKHLSRRVDRTVETEVVS 340
Query: 68 ALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRLAV 127
+ ++FG LD +N G+ + V N +E P + + + VNL G F +R A
Sbjct: 341 LFEELRERFGHLDVFVN--GM-NEILVPN-TEESP---EVLKRILDVNLTGAFTCVREAA 393
Query: 128 GLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGIRV 187
+ + V++N + + AY A AG+ +T A ++ GIR
Sbjct: 394 ISMRSGS--------VILNLGASLSLSPLAPSHAYGAYNAGIDMLTRCTAAELGPLGIRT 445
Query: 188 VTIAPGLFRTPMMEQLPEPA---IKSLEASVPFPSRLGHPQEFALLVQSI--IQNPMLNG 242
T+APG RT +L A SL +P R+G +E A + +NG
Sbjct: 446 ATVAPGYIRTCAANRLAAVAGMDSASLRQRIPL-GRVGDAEEVAEAAYFLASFDASYING 504
Query: 243 ETIRLDGSL 251
+ +DG L
Sbjct: 505 SILHVDGGL 513
>UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4;
Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella
melitensis
Length = 272
Score = 118 bits (284), Expect = 1e-25
Identities = 75/227 (33%), Positives = 117/227 (51%), Gaps = 16/227 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG---ENAVFAPVD 58
FK V +VTGG+SG+G+ATA +++G +VVI D S GQ A L E A+F D
Sbjct: 3 FKDKVVIVTGGASGIGEATARAFIREGAKVVIADF-SDHGQQLADELAGAHEQALFIKTD 61
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V V+ + T++ +GRLD + AG+A+ + + D +Q TI +NL G
Sbjct: 62 VADTRAVQALIARTVENYGRLDIMFANAGIAADAPI------DELDEAAWQKTIDINLTG 115
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
+ + A+ + GV++N S+ + G+ G AY+A+K GV +T LA
Sbjct: 116 VYLCDKYAIDQMRSQGG------GVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLAI 169
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQ 225
D Q IRV + PG TP+++ +P+ ++L A P L P+
Sbjct: 170 DYGPQNIRVNAVCPGYIDTPLLKNIPDDKKQALVALHPMGGVLAGPR 216
>UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier
protein) reductase - Leptospira interrogans
Length = 256
Score = 118 bits (284), Expect = 1e-25
Identities = 83/260 (31%), Positives = 135/260 (51%), Gaps = 23/260 (8%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
+ K VA+VTGGS+G+GKA + V +G +VV C +G+ + G + F
Sbjct: 4 IMKDKVAIVTGGSTGIGKAVVKEFVSKGVKVVFCGRRLEEGKKLESEIRAEGGDVYFVVC 63
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DVTS + VK+ + L+KFGRLD IN AG+ + + + E P D ++ + VNL
Sbjct: 64 DVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLH---EYPED--VWDKVVNVNLK 118
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
GT+ ++ + + K GVV+N +S++ +G +G Y+A+K GVVG+T A
Sbjct: 119 GTWLSMKYQIPEMIKMGG------GVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAA 172
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQL------PEPAIKSLEASVPFPSRLGHPQEFALLV 231
+ AK+ IR+ I PG +T ++++L P A + L P R+ P+E + V
Sbjct: 173 LEYAKKNIRINAICPGAVKTEILDELFHLAKDPVEAERQLVKLHPI-HRIASPEEISKTV 231
Query: 232 QSII--QNPMLNGETIRLDG 249
+ + + G I +DG
Sbjct: 232 LWLCSEDSSFITGTAIPVDG 251
>UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rhodospirillum rubrum ATCC 11170|Rep: Short-chain
dehydrogenase/reductase SDR - Rhodospirillum rubrum
(strain ATCC 11170 / NCIB 8255)
Length = 260
Score = 118 bits (284), Expect = 1e-25
Identities = 86/266 (32%), Positives = 134/266 (50%), Gaps = 25/266 (9%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVT 60
+ + VALVTGG++G+G+A A L G RVVI DL + A+++G + + PVDV
Sbjct: 6 LLRDKVALVTGGANGIGRAAARALYGAGARVVIADLDQMAAERAAEAMGGDVLGLPVDVR 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
++ + + G +D L+ AGV+S + E + VN G F
Sbjct: 66 DRTSMQTCVDRAIASCGGIDILVANAGVSSMRKAVELTDED------WAFNFDVNAKGVF 119
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
LA L+ ++ A G++GV++NTAS+AA G A Y+ASK V+G T LAR++
Sbjct: 120 ----LANQLVVRHFL-ATGRKGVIVNTASLAAKVGAPLLAHYAASKFAVLGWTQSLAREL 174
Query: 181 AKQGIRVVTIAPGLFRTPMMEQ-----------LPEPAIKSLEASVPFPSRLGHPQEFA- 228
A +GIRV + PG RTPM ++ PE K A P R+ P++ A
Sbjct: 175 APEGIRVNAVCPGFVRTPMQDREIIWEGELRGMTPEDVRKEYVALTPL-GRIEEPEDVAD 233
Query: 229 -LLVQSIIQNPMLNGETIRLDGSLRM 253
+L + + + G+ I + G ++M
Sbjct: 234 VILFLASDLSRFMTGQGINVTGGIKM 259
>UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candidatus
Pelagibacter ubique|Rep: Short chain dehydrogenase -
Candidatus Pelagibacter ubique HTCC1002
Length = 258
Score = 118 bits (284), Expect = 1e-25
Identities = 76/253 (30%), Positives = 124/253 (49%), Gaps = 18/253 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL-GEN--AVFAPVDV 59
K +A+VTGG G+G L +G ++VI ++ G+ +K + G N A+ +V
Sbjct: 4 KDRIAIVTGGGKGIGAEICVRLASEGAKIVIAEMDIENGEKISKKIQGNNGEAIVVETNV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
ED + + KFG++D L+N AG+ + + + K+Q D+ I VNL G
Sbjct: 64 AEEDSANNMADVAIKKFGKIDILVNNAGIRHINNILDHTKQQWDDM------ISVNLTGP 117
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+ + + + KN +G +IN S+A+F G+ + AY A+K+G++G+T LA D
Sbjct: 118 YLCCKSVIPHMIKNG------KGKIINFGSIASFMGRPDRVAYVAAKSGILGLTRALAVD 171
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPE-PAIKSLEASVPFPSRLGHPQEF--ALLVQSIIQ 236
+ + I V TI PGL TP ++ E P R G P + A + S
Sbjct: 172 LTGKNINVNTICPGLISTPFNQKFAEDPTHGKAWGKETIVGRWGLPSDISGAAVFLSSDD 231
Query: 237 NPMLNGETIRLDG 249
+NG I++DG
Sbjct: 232 ADFINGSEIKIDG 244
>UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus
thuringiensis
Length = 247
Score = 118 bits (283), Expect = 2e-25
Identities = 82/256 (32%), Positives = 133/256 (51%), Gaps = 20/256 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTK--GQNTAKSLGENA--VFA-PVD 58
G VA+VTGG+ G+GKA L ++G +VVI + S+K +N LG+ V+A D
Sbjct: 6 GKVAIVTGGAKGIGKAITVALAQEGAKVVI-NYNSSKEAAENLVNELGKEGHDVYAVQAD 64
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ +D ++ ++ FG++D L+N AG+ +R FKK D ++ I VNL
Sbjct: 65 VSKVEDANRLVEEAVNHFGKVDILVNNAGI---TRDRTFKKLNRED---WERVIDVNLSS 118
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
FN + I + + G +I+ +S+ G GQ YSA+KAG++G T LA
Sbjct: 119 VFNTTSAVLPYI------TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL 172
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN- 237
++AK + V I PG T M+ ++PE + + A +P R G E A V + ++
Sbjct: 173 ELAKTNVTVNAICPGFIDTEMVAEVPEEVRQKIVAKIP-KKRFGQADEIAKGVVYLCRDG 231
Query: 238 PMLNGETIRLDGSLRM 253
+ G+ + ++G L M
Sbjct: 232 AYITGQQLNINGGLYM 247
>UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Clostridium cellulolyticum H10|Rep: Short-chain
dehydrogenase/reductase SDR - Clostridium cellulolyticum
H10
Length = 246
Score = 118 bits (283), Expect = 2e-25
Identities = 75/255 (29%), Positives = 139/255 (54%), Gaps = 20/255 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL------GENAVFAPVDV 59
VA+VTGGS GLG+A L K G VV+ + + G+ K+L G + ++ D
Sbjct: 4 VAIVTGGSRGLGRAMVLRLGKMGYNVVMNYVSDSSGKECEKNLEELRKMGVDGIYIQADA 63
Query: 60 TSEDDVKEALQITLDKFG-RLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
++ + + ++ ++KFG ++D L+N AGV++ + Y K+ D ++ I+VNL+
Sbjct: 64 STYEGCETVVKAAVEKFGDKIDVLVNNAGVSNNAEFY---KQDHAD---YEWLIRVNLLS 117
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
++ RL + + + ++G +IN +S+ G I QA Y A+K+G++G T LA
Sbjct: 118 VMHMTRLVLPYM------VEAKKGNIINISSIGGLMGVINQADYCATKSGIIGFTRALAL 171
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP 238
+ A + IRV I PG+ T +++ + + + +L A++P ++G P+ A +Q +I+N
Sbjct: 172 EYASRNIRVNAICPGMIDTDILKGVNQDELNALAATIPL-GKIGDPECIAGSMQYLIEND 230
Query: 239 MLNGETIRLDGSLRM 253
G + +G + M
Sbjct: 231 YTTGVYLTPNGGIHM 245
>UniRef50_Q93HC0 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=4; Actinomycetales|Rep: 3-oxoacyl-(Acyl
carrier protein) reductase - Streptomyces avermitilis
Length = 313
Score = 117 bits (282), Expect = 3e-25
Identities = 77/254 (30%), Positives = 121/254 (47%), Gaps = 19/254 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVIC----DLPSTKGQNTAKSLGENAVFAPVDVTS 61
VALVTGGS G+G+A L G + C D + + + LG + VDVT
Sbjct: 73 VALVTGGSRGIGRAVVARLASDGYDIGFCYRSDDQAAALVEKEVRELGRRVLSRRVDVTD 132
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
V+E + ++ G A++ AG+ S + E + ++ NL GT+N
Sbjct: 133 RTQVREFVTAAEEELGPASAVVTSAGITRDSPLVLMPDED------WDAVLRTNLDGTYN 186
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ R AV P G V+ +SVA G GQ YSASK+G++G T LA++
Sbjct: 187 LCR-AVAF-----PMIKRGGGAVVTLSSVAGVAGNAGQTNYSASKSGIIGFTRSLAKEGG 240
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PM 239
+ GIR ++APG T M +LP K + +P R G P++ A LV ++ +
Sbjct: 241 RHGIRANSVAPGFIDTDMTSELPPKVAKEMLGRIPL-KRFGRPEDVAALVAFLLSSEAAY 299
Query: 240 LNGETIRLDGSLRM 253
+ G+ ++DG + +
Sbjct: 300 ITGQVFQVDGGIAL 313
>UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 248
Score = 117 bits (282), Expect = 3e-25
Identities = 86/254 (33%), Positives = 127/254 (50%), Gaps = 18/254 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
+ +G VA++TG SG+G A A L +G +V++ DL + G A L G A F V
Sbjct: 3 LLEGKVAVITGAGSGIGAAIARLFAVEGAKVLLGDL-AEGGAALAAGLAADGHAAGFQHV 61
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DVT E V E +Q + FGRLD L+ AG+ + DL ++ I V+L
Sbjct: 62 DVTDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIH-----ELDLVDWRRVIDVDLT 116
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G + A G++ A G G ++N AS+ A GQ AYSA+KA VV +T +A
Sbjct: 117 GVAICNKFAAGIMR-----ATGG-GAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVA 170
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
A QGIR ++PG TP++ +LPE +++ P RL P E A +V + +
Sbjct: 171 LTYALQGIRANCVSPGYVDTPLLAKLPEATRQAMLVRQPI-GRLARPGEIAEVVAFLASD 229
Query: 238 --PMLNGETIRLDG 249
++ G + DG
Sbjct: 230 KASIITGACVNADG 243
>UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium glutamicum|Rep: Putative oxidoreductase
- Corynebacterium glutamicum (Brevibacterium flavum)
Length = 279
Score = 117 bits (282), Expect = 3e-25
Identities = 74/202 (36%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN-AVFAPVDVTS 61
+G VA +TG +SG+G + A +L G +VVI DL GQ K +GE A + ++VTS
Sbjct: 36 EGKVAFITGAASGMGASHARVLAAHGAKVVITDLNDELGQELVKEIGEEKAHYVHLNVTS 95
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
++ + A+Q L++FG++D LIN AG+ S+ V + + TI ++L GTF
Sbjct: 96 FEEWEVAVQKALERFGKIDTLINNAGIFSSGSVEDATAAD------WDKTIAIDLNGTFY 149
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
++ A+ + +N P A +IN +S+A G +AAYSA+K GV G+T A D+
Sbjct: 150 GMKAALPALKEN-PTAS-----IINISSIAGVTGFKNRAAYSAAKWGVQGLTKTSAMDLG 203
Query: 182 KQGIRVVTIAPGLFRTPMMEQL 203
K IRV ++ PG TP+ L
Sbjct: 204 KYNIRVNSVHPGSVETPLTANL 225
>UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protein]
reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable
3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
sp. (strain RHA1)
Length = 249
Score = 117 bits (282), Expect = 3e-25
Identities = 76/256 (29%), Positives = 133/256 (51%), Gaps = 19/256 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPV---DVT 60
G +A+V GG SG+G+ATAEL + G +V + D+ TA+ L N V D+T
Sbjct: 5 GKIAIVVGGGSGIGRATAELFAENGAKVAVADINEEGAAETAEILRSNGADVSVHTCDIT 64
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+ ++ + +FGRLD + + G + + F +E D ++ I +NL+G+
Sbjct: 65 EQPQTDALVEEVVSRFGRLDMMTSTVGWSDTTF---FAQE---DAKYWRRIIDINLMGSI 118
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+ R A+G P ++ + G ++ T+S A G +G+ Y+ +KAGV+G LAR++
Sbjct: 119 FLSRSAMG------PMSEQKSGSIVLTSSDAGKVGTMGETVYAGAKAGVIGFVKSLAREI 172
Query: 181 AKQGIRVVTIAPGLFRTPMME-QLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN-- 237
A+ G+R+ I+PG TP++ Q + I + +VP R+G E A + + +
Sbjct: 173 ARDGMRINAISPGPTDTPLLRAQSDQHVIDRMVKAVPL-KRMGTASEQAAPIVFLASDYA 231
Query: 238 PMLNGETIRLDGSLRM 253
+ G+T+ + G L M
Sbjct: 232 SYITGQTLSVSGGLTM 247
>UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
2-deoxy-D-gluconate 3-dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 254
Score = 117 bits (282), Expect = 3e-25
Identities = 85/253 (33%), Positives = 130/253 (51%), Gaps = 18/253 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQN---TAKSLGENAVFAPVDV 59
+G VA+VTG GLG+A A+ LV G V + S + ++ AK+ G A+ D+
Sbjct: 9 EGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVAARTSAELESFVADAKAAGGQALACSTDI 68
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T E V+ + T++ FGR+D L+N +G+ + + + EQ D + + NL GT
Sbjct: 69 TDEASVERLVDATVETFGRVDILVNNSGIVATTPLI----EQSADE--WDRVVATNLRGT 122
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F LA +G++ + G VIN AS A G AAYSASKAGV+ T +A +
Sbjct: 123 F----LATRAVGRHL--VAQRSGKVINIASNFALQGVANHAAYSASKAGVIAFTRSMAIE 176
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPS-RLGHPQEFA--LLVQSIIQ 236
A+ I+V IAPG F T + + A + + P+ R+G P+E LL+ +
Sbjct: 177 WARDNIQVNAIAPGYFATSLNADMRADADMAAKVVRAIPARRMGEPEELTSWLLLLAGSA 236
Query: 237 NPMLNGETIRLDG 249
+ + GE I +DG
Sbjct: 237 SDFMTGEVIVIDG 249
>UniRef50_Q2UB90 Cluster: Dehydrogenases with different
specificities; n=7; Pezizomycotina|Rep: Dehydrogenases
with different specificities - Aspergillus oryzae
Length = 269
Score = 117 bits (282), Expect = 3e-25
Identities = 83/265 (31%), Positives = 124/265 (46%), Gaps = 19/265 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPST-------KGQNTAKSL----GENAVF 54
VAL+TG SSG+G+A A K+G +V DL T + + T G A++
Sbjct: 8 VALITGSSSGMGRAIALRYAKEGAHIVCADLSLTARSLVPEEAEITTHDAIIQAGGRAIY 67
Query: 55 APVDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQV 114
DV+ + A+Q + +FGRLD L+N AG+A+ +R N + D + + ++V
Sbjct: 68 VQTDVSEAQQFERAVQTAVSEFGRLDILVNNAGIATDTR--NPTRVHETDEHAWDTMLRV 125
Query: 115 NLIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTL 174
N F + + + K P + G RG VIN AS+ G +G AY ASK VV +T
Sbjct: 126 NTTSVFLGCKYGIAQMLKQEPHSSGDRGWVINLASIWGLVGGLGSPAYCASKGAVVNLTR 185
Query: 175 PLARDMAKQGIRVVTIAPGLFRTPMMEQLPEP---AIKSLEASVPFPSRLGHPQEFALLV 231
+A D I V I PG T M L E AI+SL P G+P + A +
Sbjct: 186 QMALDYGPDRIHVNAICPGFIWTAMTRDLEEASPHAIESLHQKHPLKG-FGYPDDVARMA 244
Query: 232 QSIIQN--PMLNGETIRLDGSLRMQ 254
+ + ++ G + +DG Q
Sbjct: 245 VVLASDDASLVTGVALPVDGGYTAQ 269
>UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier
protein] reductase - Anabaena sp. (strain PCC 7120)
Length = 251
Score = 117 bits (281), Expect = 3e-25
Identities = 85/258 (32%), Positives = 125/258 (48%), Gaps = 23/258 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKS----LGENAVFAPVD 58
+G VA+VTG S G+G+A A L G VV+ S+ + + G AV D
Sbjct: 9 RGQVAVVTGASRGIGRAIALELANYGATVVVNYASSSTAADEVVAEITGAGGEAVALKAD 68
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ + V + +DKF R+D L+N AG+ + + K E +Q I +NL G
Sbjct: 69 VSQVEQVDNLINGAIDKFKRIDILVNNAGITRDTLLLRMKPED------WQAVIDLNLTG 122
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
F R L+ K + G +IN SVA G GQA YSA+KAGV+G T +A+
Sbjct: 123 VFLCTRAVSKLMLKQ------RSGRIINITSVAGQMGNPGQANYSAAKAGVIGFTKTVAK 176
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP 238
++A +GI V +APG T M L I +P R G P+E A +V+ + +P
Sbjct: 177 ELASRGITVNAVAPGFIATDMTSNLKSEGILQY---IPL-GRYGQPEEIAGMVRFLAADP 232
Query: 239 ---MLNGETIRLDGSLRM 253
+ G+ +DG + M
Sbjct: 233 AAAYITGQVFNVDGGMVM 250
>UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like
protein; n=1; Hahella chejuensis KCTC 2396|Rep:
Short-chain alcohol dehydrogenase-like protein - Hahella
chejuensis (strain KCTC 2396)
Length = 251
Score = 117 bits (281), Expect = 3e-25
Identities = 82/258 (31%), Positives = 126/258 (48%), Gaps = 18/258 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVT 60
G V +VTG SSG+G+ TA L G +V + S + ++T + + G A+ P DV+
Sbjct: 5 GKVVMVTGASSGIGRTTAIKLANYGAKVAVIARRSRESEDTVRHITEAGGQAISIPADVS 64
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
SE D+K AL ++ FG+LD N AG A EQ +D +N G +
Sbjct: 65 SESDIKNALAQIIETFGKLDGAFNNAGAAEPVGPLTELSEQEWD-----RVFSINTKGAW 119
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQ-IGQAAYSASKAGVVGMTLPLARD 179
++ + + N + G ++N +S+ G +G AAY ASK ++G+T + +
Sbjct: 120 LCMKHQIPALLSN------KSGAIVNMSSIYGLVGTGMGLAAYVASKHAIIGLTKAASLE 173
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQ-LPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN- 237
A + IR+ I PG TP EQ L P + + S+ RLG QE A V ++ +
Sbjct: 174 YAARNIRINAICPGWIPTPGNEQALSNPEVMAFAQSLHPQGRLGTQQEVAEAVCWMLSDS 233
Query: 238 -PMLNGETIRLDGSLRMQ 254
LNG+TI +DG Q
Sbjct: 234 ASYLNGQTISIDGGYTAQ 251
>UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=16; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase -
Synechococcus sp. (strain RCC307)
Length = 250
Score = 117 bits (281), Expect = 3e-25
Identities = 84/257 (32%), Positives = 126/257 (49%), Gaps = 23/257 (8%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL----GENAVFAPVDV 59
G +ALVTG S G+G+A A L + G VV+ S S G +A DV
Sbjct: 9 GQIALVTGASRGIGRAIALQLAEAGAEVVVNYASSADAAEQVVSAITAAGGSAYALKADV 68
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+ ED V++ + L+K GR+D LIN AG+ + K +Q + +NL G
Sbjct: 69 SQEDQVEQLMAAVLEKSGRIDVLINNAGITRDGLLMRMKTPD------WQAVLDLNLSGV 122
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F R + K ++G +IN SV G GQA Y+A+KAGV+G T AR+
Sbjct: 123 FLCTRAVTRTMLKQ------KQGRIINITSVVGLMGNAGQANYAAAKAGVIGFTKSTARE 176
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP- 238
+A +GI V +APG T M + L A ++L ++P R G E A V+ + +P
Sbjct: 177 LASRGITVNAVAPGFIATDMTKDL---AAEALLNAIPL-GRYGEVDEVAGAVRFLAADPA 232
Query: 239 --MLNGETIRLDGSLRM 253
+ G+ +++DG + M
Sbjct: 233 AAYITGQVLQVDGGMVM 249
>UniRef50_A4F720 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=10; Actinobacteria (class)|Rep:
3-oxoacyl-[acyl-carrier protein] reductase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 253
Score = 117 bits (281), Expect = 3e-25
Identities = 72/206 (34%), Positives = 112/206 (54%), Gaps = 19/206 (9%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTS 61
F GLVA VTGG+SG+G ATA LL ++G V + DL +GE+ + DVT
Sbjct: 4 FDGLVAAVTGGASGIGLATARLLAERGAAVAVLDL-------RPHDVGESLLGVRCDVTD 56
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+ +V+ A++ ++FG LD L+N AG+ + + D + + + VN++G
Sbjct: 57 DGEVRSAVEAVRERFGGLDVLVNNAGIGAQGDI------SANDDAEWHHVLDVNVVGIAR 110
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
V R A+GL+ + + ++NT S+A G +A YSASK V +TL +A D
Sbjct: 111 VSRAALGLLRAS------EHAAIVNTCSIAGIAGLPQRALYSASKGAVRALTLAMAADHV 164
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPA 207
++GIRV +APG TP + +L + A
Sbjct: 165 REGIRVNCVAPGTVDTPWIGRLLDSA 190
>UniRef50_A3PQM4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rhodobacter sphaeroides ATCC 17029|Rep: Short-chain
dehydrogenase/reductase SDR - Rhodobacter sphaeroides
(strain ATCC 17029 / ATH 2.4.9)
Length = 240
Score = 117 bits (281), Expect = 3e-25
Identities = 84/228 (36%), Positives = 117/228 (51%), Gaps = 26/228 (11%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G V LVTGG+SG+G++ AE+ V+ G R ICDL + E V DVT
Sbjct: 8 GKVVLVTGGASGIGRSVAEVCVELGARTAICDLAPGEAP-------EGQVALNCDVTDPA 60
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDL---NIFQNTIQVNLIGTF 120
V+ A + FGR+DA++NCAGV + + + P + I VNL GTF
Sbjct: 61 AVERAFAAAREAFGRVDAVVNCAGV------WRPRSDGPITAVSDETWDRIIAVNLTGTF 114
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
NV R AV ++ +A G G ++ ASV A G AYSASK GV+ ++ LA +
Sbjct: 115 NVCREAVRVM-----EAQGH-GSIVTIASVVAITGWEKLNAYSASKGGVLSLSRALAIEC 168
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA 228
+ IRV I PG+ TPM E++ + + V RLGHP++ A
Sbjct: 169 GPKNIRVNCICPGVIETPMTEKV----LAYSQPDVLPIGRLGHPRDIA 212
>UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=6; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Paracoccus
denitrificans (strain Pd 1222)
Length = 253
Score = 117 bits (281), Expect = 3e-25
Identities = 84/233 (36%), Positives = 121/233 (51%), Gaps = 20/233 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
K V L+TG +G+G ATA+L +++G RVV+ D + A LGENA VDV+
Sbjct: 6 KDKVVLITGAGAGIGAATAKLFIEEGARVVVADYLGDAAEQVAAELGENARAFTVDVSKA 65
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ K + T+ +FG LD L+N AG S V + D N +++ I VNL G +
Sbjct: 66 EACKAMVDFTVAEFGGLDVLVNNAGRGSLGTV------ETQDENDWRSIIDVNLTGVYLC 119
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQI-GQAAYSASKAGVVGMTLPLARDMA 181
+ AV + K G ++NTAS A I +AAY A+K GV +T +A D A
Sbjct: 120 SKYAVPELRKRG------GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMALDFA 173
Query: 182 KQGIRVVTIAPGL----FRTPMMEQLPEP-AIKS-LEASVPFPSRLGHPQEFA 228
IRV ++APG+ + M+ Q+P+P A K+ L A P S G P + A
Sbjct: 174 ADNIRVNSVAPGVIWSNYYNKMLTQVPDPEAFKAGLRARAPSNS-WGEPDDIA 225
>UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1;
Terrabacter sp. DBF63|Rep: Short-chain
dehydrogenase/redutase - Terrabacter sp. DBF63
Length = 252
Score = 116 bits (280), Expect = 4e-25
Identities = 82/233 (35%), Positives = 119/233 (51%), Gaps = 17/233 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL--GENAVFAPVDVTS 61
G VALVTGG G+G+ TA++LV G RVV+ DL G T + + G+ F DVT
Sbjct: 7 GKVALVTGGGGGIGRETAKVLVDHGARVVVADLSEDAGNGTLEYIDGGDAVAFVRADVTD 66
Query: 62 EDDVKEALQITLDKFGRLDALINCAGV-ASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
++ +Q +D++GRLD N AG+ + + + EQ F I VNL G F
Sbjct: 67 LASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQ------FDKVIAVNLTGVF 120
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
++ + + A G G +INTAS Q+AY SK GV+G+T A +
Sbjct: 121 ISMKAEIPQML-----AQGG-GSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAAVEY 174
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPE--PAIKSLEASVPFPSRLGHPQEFALLV 231
+ +GIRV + PG+ +TPM++ L E P K + RLG P + A +V
Sbjct: 175 SDKGIRVNAVLPGVIQTPMIDALEETYPGFKDALLTKHPIGRLGTPHDIAEMV 227
>UniRef50_Q03RV5 Cluster: 3-oxoacyl-acyl carrier protein reductase;
n=1; Lactobacillus brevis ATCC 367|Rep: 3-oxoacyl-acyl
carrier protein reductase - Lactobacillus brevis (strain
ATCC 367 / JCM 1170)
Length = 241
Score = 116 bits (280), Expect = 4e-25
Identities = 77/247 (31%), Positives = 119/247 (48%), Gaps = 14/247 (5%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPS-TKGQNTAKSLGENAVFAPVDVTSEDD 64
VA+VTG +G+G A AE +K G RV++ + T A+ DVT E
Sbjct: 6 VAIVTGAGTGIGFAIAEQFLKVGIRVILNSHHELAPAEQTIIDQYSTAIVVTGDVTQETT 65
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
E + ++ FGRLD LIN AG+ + F + N+ G FN+ +
Sbjct: 66 ADELVTQAMNHFGRLDILINNAGITRDKLLTRMAAAD------FTAVMTTNVFGAFNLTK 119
Query: 125 LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
A+ ++ K ++G ++N +S++ G IGQA Y+ASKA +VG+T A++ A +
Sbjct: 120 AAMKVMQK------ARQGAIVNLSSISGLHGNIGQANYAASKAAIVGLTKASAKEGALRQ 173
Query: 185 IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGET 244
IRV IAPG+ T M + E + +P R G E A ++ N + G+
Sbjct: 174 IRVNAIAPGMIATAMTGAMSEKRQAAAREVIPL-KRFGTVAEIATTALFLVNNAYITGQV 232
Query: 245 IRLDGSL 251
I +DG L
Sbjct: 233 ITVDGGL 239
>UniRef50_A1R756 Cluster: Putative 3-oxoacyl-(Acyl carrier protein)
reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative
3-oxoacyl-(Acyl carrier protein) reductase -
Arthrobacter aurescens (strain TC1)
Length = 238
Score = 116 bits (280), Expect = 4e-25
Identities = 79/250 (31%), Positives = 123/250 (49%), Gaps = 20/250 (8%)
Query: 8 LVTGGSSGLGKATAELLVKQGGRVVIC----DLPSTKGQNTAKSLGENAVFAPVDVTSED 63
+V G S G+GKA A L G +VI D + + + LG A+ VDV+ E
Sbjct: 1 MVVGASRGIGKACALELAASGHDIVIFYRQDDEGAARTVEAIQELGRKALAVRVDVSVEA 60
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
DV+ A + L FGR+ +++ +G+ + + LN + I NL G F V
Sbjct: 61 DVRAAFRAVLKDFGRIRSVVYSSGITADGLLATMS------LNNWDRVISTNLTGAFLVC 114
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
R +V + K G ++ +S + GQ GQA YSA+K G+ +T +A++MA
Sbjct: 115 RESVKALRKTG-------GSIVLISSTSGISGQPGQANYSATKGGINALTQSMAKEMASF 167
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPMLN 241
GIRV +APG T M++Q+ A + +P R+G P E A V +I Q+ +
Sbjct: 168 GIRVNAVAPGFTNTDMLKQMDAKARREYTQHIPL-QRIGEPHEIAAAVAFLIGHQSSYIT 226
Query: 242 GETIRLDGSL 251
G+ + +DG L
Sbjct: 227 GQVLAVDGGL 236
>UniRef50_Q0U998 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 303
Score = 116 bits (280), Expect = 4e-25
Identities = 68/198 (34%), Positives = 109/198 (55%), Gaps = 9/198 (4%)
Query: 8 LVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA--KSLGE--NAVFAPVDVTSED 63
+VTG ++G+G T G VVI DLP TK A SL + A++ P D+TS +
Sbjct: 16 IVTGSANGIGAQTIRSYHSAGCNVVIADLPFTKDAAEAVISSLSDPGRAMYHPTDITSWN 75
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNI---FQNTIQVNLIGTF 120
D++ + T ++FG++D ++ AG+ + + F++++ +L + VNL GT
Sbjct: 76 DIRVLFRETKNRFGQIDVVVANAGLMESKGFFEFEEDEAGELKEPVEAYKVVDVNLKGTM 135
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
N +RLA+ + N PD+DG +G V+ AS + + G G +Y +SK GVVG+ R
Sbjct: 136 NTLRLAMHFMSSNPPDSDGAKGSVVLVASTSGYFGGTGVVSYISSKHGVVGLARASQRKA 195
Query: 181 AKQGIRVVTIAPGLFRTP 198
+ G+RV +AP F TP
Sbjct: 196 KELGVRVNVVAP--FFTP 211
>UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductase;
n=10; Bacteria|Rep: 3-oxoacyl-acyl carrier protein
reductase - Deinococcus radiodurans
Length = 254
Score = 116 bits (279), Expect = 6e-25
Identities = 83/252 (32%), Positives = 123/252 (48%), Gaps = 19/252 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVI-CDLPSTKGQNTA---KSLGENAVFAPVDVTS 61
VALVTG S GLG+A A L + G V + + Q A ++ G A D++
Sbjct: 13 VALVTGSSRGLGRAMALRLAQDGFTVAVHYGRGEAEAQQVAADIRAAGGAAQVFGADLSQ 72
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+ ++ + GRLD L+N AG+ K E + +Q NL F
Sbjct: 73 PANAGTLVEDVIAALGRLDVLVNNAGITRDGLAIRMKDED------WDAVLQTNLSSAFA 126
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
R A+ + KN + G ++N +SV A G GQA Y ASKAG++G+T LA++
Sbjct: 127 ACRAALKHMMKN------RSGRIVNVSSVVALAGNPGQANYVASKAGLIGLTRALAKEYG 180
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PM 239
+GI V IAPG + M +LPE K +A++P +R G P+E A LV +
Sbjct: 181 GRGITVNAIAPGFIESDMTAKLPEDTKKQYQANIPL-ARFGQPEEVAALVAFLASEGAGY 239
Query: 240 LNGETIRLDGSL 251
+ G+TI +DG +
Sbjct: 240 ITGQTIGVDGGM 251
>UniRef50_A3K113 Cluster: Short chain dehydrogenase; n=1; Sagittula
stellata E-37|Rep: Short chain dehydrogenase - Sagittula
stellata E-37
Length = 240
Score = 116 bits (279), Expect = 6e-25
Identities = 83/250 (33%), Positives = 121/250 (48%), Gaps = 21/250 (8%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G L+TG + G+G+A + G R+V+ DL + + GE A+ P DVT
Sbjct: 7 GQTVLITGAAGGIGRAMTDAFSSAGARLVLSDLDVAELPS-----GETALPLPCDVTDAA 61
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
V+ + +FG+LD IN AG++ F + I VNL GTFN +
Sbjct: 62 SVRAVVAEAQKRFGQLDIAINNAGISGP-----FGTLSQLSAEDWSRLIAVNLTGTFNAL 116
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ + + DG R ++N AS+A G G AAY+A+K GVVG+T LA ++ KQ
Sbjct: 117 QAEIPAM------RDGGR--ILNVASLAGVAGAPGLAAYAATKHGVVGLTRSLAHELRKQ 168
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEF--ALLVQSIIQNPMLN 241
IRV + P TPM++ + P E + R G QE A L + QN +N
Sbjct: 169 RIRVNALCPSFTETPMLDSM-GPEKTRFETPLNALGRFGTAQEMADAALWITSPQNSFMN 227
Query: 242 GETIRLDGSL 251
G+ I LDG +
Sbjct: 228 GQAITLDGGI 237
>UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=1; Bacillus thuringiensis serovar
israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier
protein] reductase - Bacillus thuringiensis serovar
israelensis ATCC 35646
Length = 248
Score = 116 bits (278), Expect = 8e-25
Identities = 86/258 (33%), Positives = 128/258 (49%), Gaps = 20/258 (7%)
Query: 1 MFKGL-VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNT-AKSLGENAVFA--- 55
MF G VALV GGS G+GKA L QG V + K N A ++GE A
Sbjct: 1 MFNGNEVALVIGGSRGIGKAITMDLANQGLIVYFTFQSNQKSANEIANTIGEKGGQAFPM 60
Query: 56 PVDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVN 115
VD+T+ED + + Q K R+D L+N AGV + +E+ + + + +N
Sbjct: 61 HVDITNEDSIHKLFQHIRSKEKRIDILVNNAGVINDGFAAMMSEEK------WDHVVDLN 114
Query: 116 LIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
L GTF R A+ ++ + +RG ++N S + G GQ YSASK GV+ +T
Sbjct: 115 LKGTFLCCRQALRIMMRQ------KRGSIVNITSTSGITGARGQCNYSASKGGVISLTKT 168
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
LA + + GIRV +APG +T M + + + +K + VP R+G P+E A L +
Sbjct: 169 LALEGGEYGIRVNAVAPGFIQTDMTKGMDQQTLKRMLELVPL-GRIGDPKEVAHLTTFLS 227
Query: 236 QN--PMLNGETIRLDGSL 251
N + G+ +DG L
Sbjct: 228 SNYASYITGKVFTVDGGL 245
>UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
reductase, putative; n=10; Bacillus cereus group|Rep:
3-oxoacyl-(Acyl-carrier-protein) reductase, putative -
Bacillus anthracis
Length = 246
Score = 115 bits (277), Expect = 1e-24
Identities = 73/255 (28%), Positives = 130/255 (50%), Gaps = 19/255 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVT 60
G A+VTG + G+GK A + K G +V+I D+ K Q T + L G DV+
Sbjct: 6 GKTAVVTGAAQGIGKEIARVYAKLGAKVLISDVNEEKLQKTTRELLDEGYEVSLYRCDVS 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
++++ K ++ + KFG L L+N AG+ + ++ +K ++ +QVNL G F
Sbjct: 66 NQNEAKSLIEYAVQKFGTLHILVNNAGITRDAMLHKMEKSS------WEQVLQVNLTGVF 119
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
++ A+ + + G +IN +S++ +G IGQA Y+A+KAGVVG+T A+++
Sbjct: 120 YCMQPALLYMRQQG------YGRIINISSISR-EGNIGQANYAATKAGVVGLTKTAAKEV 172
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--P 238
GI I PG T + +P+ + + ++P R+G P++ A +
Sbjct: 173 GSFGITCNAICPGFMDTDTTKTIPDKVKEKMVGAIPV-GRIGTPEDIANAAAFLASEYAS 231
Query: 239 MLNGETIRLDGSLRM 253
+ GE + + G L++
Sbjct: 232 YITGEVLNVSGGLQV 246
>UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4;
Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase
- Clostridium perfringens (strain SM101 / Type A)
Length = 253
Score = 115 bits (277), Expect = 1e-24
Identities = 81/259 (31%), Positives = 132/259 (50%), Gaps = 26/259 (10%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE--------NAVF 54
K V +VTGG+ G+G AT + + G +V +C ++ + K+L E +A+
Sbjct: 9 KNKVVIVTGGTRGIGFATVKKFLDHGAKVALC---GSRKETVDKALEELNYINPNYDAIG 65
Query: 55 APVDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQV 114
++ ++VKE + L+K+G +D LIN AGV+ +Y E F I +
Sbjct: 66 FYPNLLDSNEVKEMVDKVLEKWGTIDILINNAGVSDNKSIYTQSDED------FSKIIDI 119
Query: 115 NLIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTL 174
N+ FN + AV I KN + GV++NT+SV + GQ Y SK V G+T
Sbjct: 120 NVKAIFNCTK-AVSEIMKNK-----KYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTK 173
Query: 175 PLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEF--ALLVQ 232
LAR++ + GIRV +APG+ T M+ L + + + +VP R+G P++ A L
Sbjct: 174 SLARELGRDGIRVNAVAPGIIATDMVAALDKKLVDQIAQNVPL-GRVGEPEDIANAFLFL 232
Query: 233 SIIQNPMLNGETIRLDGSL 251
+ ++GE + +DGS+
Sbjct: 233 ASDMASYISGEILSVDGSV 251
>UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: Short-chain dehydrogenase/reductase SDR
precursor - Herpetosiphon aurantiacus ATCC 23779
Length = 247
Score = 115 bits (277), Expect = 1e-24
Identities = 80/235 (34%), Positives = 122/235 (51%), Gaps = 17/235 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN---AVFAPV 57
M G VA+VTGG+ G+G ATA+LL KQG VVI D+ G T + + N A F
Sbjct: 1 MLNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHC 60
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+ E D++ +Q LD+ G LD +IN AG+ + + + +Q + ++L
Sbjct: 61 DVSHEADIQALVQFALDQ-GGLDIMINNAGIGGKPAPLHLTEN-----HNWQRVLDIDLT 114
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G F + A A A G+ G ++N AS+A G Y +KAGV+ M+ A
Sbjct: 115 GVFWGQKYA-----SQAMLAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSKTGA 169
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKS-LEASVPFPSRLGHPQEFALLV 231
++A GIR+ + PG T +++ EP+++ L S+P R+G P E A L+
Sbjct: 170 IELASAGIRINAVCPGWTETAILDTF-EPSVQERLIRSIPL-KRMGTPHEIAELI 222
>UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3;
Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 -
Eubacterium sp. (strain VPI 12708)
Length = 249
Score = 115 bits (277), Expect = 1e-24
Identities = 85/256 (33%), Positives = 133/256 (51%), Gaps = 24/256 (9%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE----NAV--FAPVDV 59
+ ++TGG+ G+G A A+L ++ G +V I + L E V FAP D+
Sbjct: 8 ITIITGGTRGIGFAAAKLFIENGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAP-DL 66
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
TS D V A+ K+GRLD +IN AG+ S V++ E+ F +N + +N+ G
Sbjct: 67 TSRDAVMAAVGTVAQKYGRLDVMINNAGITMNS-VFSRVSEEDF-----KNIMDINVNGV 120
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
FN A + D ++GV+INTASV G + Y SKAGV+G+T L R+
Sbjct: 121 FNGAWSAYQCM------KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGRE 174
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA---LLVQSIIQ 236
+ ++ IRVV +APG+ T M + LP ++ ++P R+ P+E A L + S +
Sbjct: 175 IIRKNIRVVGVAPGVVDTDMTKGLPPEILEDYLKTLPM-KRMLKPEEIANVYLFLASDLA 233
Query: 237 NPMLNGETIRLDGSLR 252
+ + TI +DG+ R
Sbjct: 234 SG-ITATTISVDGAYR 248
>UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular
organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus
iheyensis
Length = 256
Score = 115 bits (276), Expect = 1e-24
Identities = 79/229 (34%), Positives = 112/229 (48%), Gaps = 16/229 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDVTSE 62
VA+VTG + G+GKATA L + +VVI D KGQ K G A F VD++
Sbjct: 10 VAIVTGAAMGMGKATAILFAESKAKVVIADFNEEKGQEVVEEVKQAGGQAAFIKVDISDS 69
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
VK+ +Q +D+FG+LD +N A + K FD + + I V+L GT
Sbjct: 70 AQVKQMVQFAVDQFGKLDIAVNNAALTPDD-----KPASEFDEDYWDKLISVDLTGTALC 124
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
++ + + + G G ++N +SV+ F Q AY A+K GVVGMT A +
Sbjct: 125 MKYELQQLLEQ-----GNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTKVAALENGP 179
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVP---FPSRLGHPQEFA 228
Q IRV T+APG TPM+ E + E P +R G +E A
Sbjct: 180 QNIRVNTVAPGAIDTPMLRGALEQFNHTEEEYAPQLSLLNRFGQAREVA 228
>UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Geobacter metallireducens
(strain GS-15 / ATCC 53774 / DSM 7210)
Length = 258
Score = 115 bits (276), Expect = 1e-24
Identities = 86/235 (36%), Positives = 125/235 (53%), Gaps = 18/235 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VA+VTG +SGLG A+A LL ++G RVVI D+ GQ A SLGE A+F DV+ E
Sbjct: 5 EGKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLGEGAIFLRHDVSDE 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
++ TL +FGRLD L+N AGV + V + E D F N + + GTF
Sbjct: 65 AQWVAIIEQTLSRFGRLDILVNNAGVVVVADVEHTTVE---DWR-FVNAVGTD--GTFFG 118
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA- 181
+ A+ + ++ G ++N +S+A G AYSASK + MT +A A
Sbjct: 119 CKHAIPAMRRSG------GGSIVNLSSLAGIGGYPLVFAYSASKGAIRAMTKSVAVHCAQ 172
Query: 182 -KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASV----PFPSRLGHPQEFALLV 231
K IR +I PG TP++E + A+ + +AS+ S+LG P + A +V
Sbjct: 173 NKYNIRCNSIHPGGILTPLVEGFIKSAVGTADASMDKARDLFSKLGEPDDVAYMV 227
>UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep:
3-oxoacyl-(Acyl-carrier protein) reductase -
Flavobacteriales bacterium HTCC2170
Length = 245
Score = 115 bits (276), Expect = 1e-24
Identities = 73/217 (33%), Positives = 115/217 (52%), Gaps = 16/217 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
K +A+VTGG+ G+G+A +EL K+G V+I DL +GQ A+ + G A + + V
Sbjct: 4 KDKIAVVTGGARGIGQAVSELFAKEGATVIIMDL-LPQGQAVAEGIIASGGKAEYHSLSV 62
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T++ DV+ DK+G++D LIN AG+ + R E +D I+VNL G
Sbjct: 63 TNKSDVEGVFSSVNDKYGKIDILINNAGI-TRDRTLEKMSEAEWDA-----VIEVNLKGV 116
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F + V + + + G +++ AS G GQ Y+A+KAGV+ M +
Sbjct: 117 FICTQAVVPYMKAS------KYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMAKTWTVE 170
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVP 216
K GI IAPG T M++Q+PE ++++AS+P
Sbjct: 171 FGKYGITANAIAPGFTMTDMVKQIPEEHFEAIKASIP 207
>UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Marinobacter sp. ELB17
Length = 264
Score = 115 bits (276), Expect = 1e-24
Identities = 74/201 (36%), Positives = 104/201 (51%), Gaps = 12/201 (5%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAP--VDV 59
F G A+VTG SG+G+ATA L +G +V++ D T + E A + VDV
Sbjct: 4 FDGRAAIVTGAGSGIGRATALRLACEGAQVIMADTSELGLAETGNLMPEGAEYLRRLVDV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
E VKE + +D FG++D L N AG+AS + + E D + + VNLIGT
Sbjct: 64 ADEAQVKELVSDAMDAFGKIDILCNIAGIASTGKGHPPVIENERDE--WDKVLSVNLIGT 121
Query: 120 FNVIRLAVGLIGKNAPDADGQR-GVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
+I+ AP ++ G ++NTAS+A G AYSASKAGV+ +T+ A
Sbjct: 122 MLLIKHV-------APHMQARKLGSIVNTASIAGIRSGAGGNAYSASKAGVINLTMTAAC 174
Query: 179 DMAKQGIRVVTIAPGLFRTPM 199
D+ IRV + PGL T M
Sbjct: 175 DLGDHNIRVNAVCPGLVETGM 195
>UniRef50_P50160 Cluster: Sex determination protein tasselseed-2;
n=109; Magnoliophyta|Rep: Sex determination protein
tasselseed-2 - Zea mays (Maize)
Length = 336
Score = 115 bits (276), Expect = 1e-24
Identities = 72/198 (36%), Positives = 104/198 (52%), Gaps = 8/198 (4%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VA+VTGG+ G+G+A L K G RVVI D+ G+ A +LG F DV+ ED
Sbjct: 55 GKVAIVTGGARGIGEAIVRLFAKHGARVVIADIDDAAGEALASALGPQVSFVRCDVSVED 114
Query: 64 DVKEALQITLDKF-GRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
DV+ A+ L + GRLD N AGV + + FD F ++VN +G
Sbjct: 115 DVRRAVDWALSRHGGRLDVYCNNAGVL-GRQTRAARSILSFDAAEFDRVLRVNALGA--- 170
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
A+G+ A + G +++ ASVAA G +G AY+ASK +VG+T A ++
Sbjct: 171 ---ALGMKHAARAMAPRRAGSIVSVASVAAVLGGLGPHAYTASKHAIVGLTKNAACELRA 227
Query: 183 QGIRVVTIAPGLFRTPMM 200
G+RV ++P TPM+
Sbjct: 228 HGVRVNCVSPFGVATPML 245
>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 254
Score = 114 bits (275), Expect = 2e-24
Identities = 80/263 (30%), Positives = 134/263 (50%), Gaps = 25/263 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG--ENAVFAPV-DV 59
+G V L+TGG+ G+G+ATA+LL+ G +V + D+ +SL ++ VF +V
Sbjct: 2 EGKVVLITGGAGGIGQATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDRVFTITGNV 61
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T E+DV+ ++ T+D+FG++D N AGV D F+ + +N+ G
Sbjct: 62 TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPIT-----ELDQATFEKIMSINVTGV 116
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F ++ + + K G ++NTAS AA+ G G +Y ASK V G+T A +
Sbjct: 117 FLGLKHVMKQMKKQG------YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAALE 170
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQL--------PEPAIKSLEASVPFPSRLGHPQEFALLV 231
+A GIRV +AP T M+ + PE + ++L+ +P R G P+E A +V
Sbjct: 171 VASDGIRVNAVAPAAIDTQMLADIQNNLTPGEPEKSGEALKQGIP-AGRFGAPEEVAQVV 229
Query: 232 QSIIQN--PMLNGETIRLDGSLR 252
+ + + +NG +DG ++
Sbjct: 230 KFLASDDASFVNGSLYNVDGGMQ 252
>UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=6; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Frankia sp. (strain CcI3)
Length = 277
Score = 114 bits (275), Expect = 2e-24
Identities = 82/251 (32%), Positives = 122/251 (48%), Gaps = 18/251 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVTSE 62
VAL+TG SG+G A A L + G RVV DL + + ++ G A+ DVT
Sbjct: 37 VALLTGAGSGIGAACARRLARAGARVVATDLDAHTVKEVVATIEDGGGEALALEADVTDP 96
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
D ++ A+Q+T+ FGRLD +N AGV++ Q + Q + VNL G F
Sbjct: 97 DSLERAVQVTVGTFGRLDLAVNNAGVSAGREPVETTPAQDW-----QRVLDVNLSGVFYS 151
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+R + + + G G ++N ASV G G A Y A+K GV+G+T A D A
Sbjct: 152 MRAEITAMLR------GDGGSIVNMASVLGVVGFAGSAPYVAAKHGVIGLTKTAALDYAT 205
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PML 240
+GIRV +APG TP++ P + P +RLG E A +V ++ + ++
Sbjct: 206 RGIRVNAVAPGFVDTPLLHVDGRPR-RGAALFSPI-NRLGTVDEVAEVVVFLLSDRASLV 263
Query: 241 NGETIRLDGSL 251
G DG +
Sbjct: 264 TGSVYLADGGM 274
>UniRef50_A6W805 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Kineococcus radiotolerans SRS30216|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Kineococcus radiotolerans SRS30216
Length = 235
Score = 114 bits (275), Expect = 2e-24
Identities = 89/248 (35%), Positives = 125/248 (50%), Gaps = 27/248 (10%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
VALVTGG+ G+G A L +G RV + D T SLGE V A D T V
Sbjct: 6 VALVTGGAGGIGAAVVAALEAEGTRVAVLD-------RTETSLGELQVGA--DTTDPAQV 56
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ A+ + + GRLD L+NCAGVA+ + DL ++ T+ VNL G F V +
Sbjct: 57 RAAVDEVVARAGRLDVLVNCAGVATIAPALEI------DLAGWERTVAVNLTGAFVVAQT 110
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
+ ++ G R ++ AS AA G G AY+ASKAG++GMT LA + GI
Sbjct: 111 ----VARHLAAHGGGR--IVTIASQAATVGLAGHVAYAASKAGLLGMTRTLALEWGPLGI 164
Query: 186 RVVTIAPGLFRTPMME-QLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP---MLN 241
V T++P + TP+ PA ++L A +P R P+E A V + P M+N
Sbjct: 165 TVNTVSPTVVLTPLARPNWENPAGEALRAQIPV-GRFAEPEEVAAAV-VFLTGPGAAMVN 222
Query: 242 GETIRLDG 249
G + +DG
Sbjct: 223 GHDLVVDG 230
>UniRef50_Q29HP4 Cluster: GA17551-PA; n=1; Drosophila
pseudoobscura|Rep: GA17551-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 251
Score = 114 bits (275), Expect = 2e-24
Identities = 79/215 (36%), Positives = 111/215 (51%), Gaps = 13/215 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFA-PVDVTSE 62
G VALVTG SG+G+AT LL + G +V+ D Q TAK LG A VDV+S
Sbjct: 8 GKVALVTGAGSGIGRATCRLLARDGAKVIAADRNLQSAQETAKELGAGRSAALEVDVSSA 67
Query: 63 DDVKEALQITLDKFGRLDALI-NCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
V+ A+ L KF R +++ N AG+ + E+ FD + VNL GTF
Sbjct: 68 KSVQGAVAEALLKFDRAPSIVVNSAGITRDGYLLKMP-ERDFD-----DVYSVNLKGTFF 121
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
V + K + + G ++N +S+ A +GQA Y+A+KAGV+ T +++
Sbjct: 122 VTQY----FAKAMIEQQLEGGSIVNLSSIVARMNNVGQANYAATKAGVISFTEVASKEFG 177
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVP 216
K GIRV I PG TPM+ +PEP IK +P
Sbjct: 178 KFGIRVNCILPGYIDTPMVAVVPEP-IKQEVVELP 211
>UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2;
Pichia|Rep: (R)-2-octanol dehydrogenase - Pichia
finlandica
Length = 254
Score = 114 bits (275), Expect = 2e-24
Identities = 84/263 (31%), Positives = 136/263 (51%), Gaps = 23/263 (8%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNT------AKSLG-ENAVF 54
F VA+VTG SG+G + A+ ++ G +V I D+ K + A++L +N +
Sbjct: 5 FHNKVAVVTGALSGIGLSVAKKFLQLGAKVTISDVSGEKKYHETVVALKAQNLNTDNLHY 64
Query: 55 APVDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQV 114
D + E+D K+ + TL FG LD + AG+ + + E PFD +++ I V
Sbjct: 65 VQADSSKEEDNKKLISETLATFGGLDIVCANAGIGKFAPTH----ETPFD--VWKKVIAV 118
Query: 115 NLIGTFNVIRLAVGL-IGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMT 173
NL G F + +LA+ + K+ P GV++N SV +F G A Y A+K GV +T
Sbjct: 119 NLNGVFLLDKLAINYWLEKSKP------GVIVNMGSVHSFVAAPGLAHYGAAKGGVKLLT 172
Query: 174 LPLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQS 233
LA + A GIRV ++ PG TP+++++P+ + L + P RLG P+E A V
Sbjct: 173 QTLALEYASHGIRVNSVNPGYISTPLIDEVPKERLDKLVSLHPI-GRLGRPEEVADAVAF 231
Query: 234 II--QNPMLNGETIRLDGSLRMQ 254
+ + +NG ++ +DG Q
Sbjct: 232 LCSQEATFINGVSLPVDGGYTAQ 254
>UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase, chloroplast precursor; n=80; cellular
organisms|Rep: 3-oxoacyl-[acyl-carrier-protein]
reductase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 319
Score = 114 bits (275), Expect = 2e-24
Identities = 79/253 (31%), Positives = 127/253 (50%), Gaps = 20/253 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTK-GQNTAKSL---GENAVFAPVDVTS 61
V ++TG S G+GKA A L K G +V++ S K + AK + G A+ DV+
Sbjct: 78 VVVITGASRGIGKAIALALGKAGCKVLVNYARSAKEAEEVAKQIEEYGGQAITFGGDVSK 137
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
DV ++ LDK+G +D ++N AG+ + + K+ Q + I +NL G F
Sbjct: 138 ATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQ------WDEVIALNLTGVFL 191
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ AV ++ K +RG +IN +SV G IGQA Y+A+K GV+ + AR+ A
Sbjct: 192 CTQAAVKIMMKK------KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGA 245
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP--- 238
+ I V + PG + M +L E K + ++P R G +E A LV+ + +P
Sbjct: 246 SRNINVNVVCPGFIASDMTAELGEDMEKKILGTIPL-GRYGKAEEVAGLVEFLALSPAAS 304
Query: 239 MLNGETIRLDGSL 251
+ G+ +DG +
Sbjct: 305 YITGQAFTIDGGI 317
>UniRef50_Q67RY1 Cluster: Putative 3-oxoacyl-(Acyl-carrier protein)
reductase; n=1; Symbiobacterium thermophilum|Rep:
Putative 3-oxoacyl-(Acyl-carrier protein) reductase -
Symbiobacterium thermophilum
Length = 248
Score = 114 bits (274), Expect = 2e-24
Identities = 83/252 (32%), Positives = 128/252 (50%), Gaps = 19/252 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKG-QNTAKSL---GENAVFAPVDV 59
G ALVTG S GLG A A L + G V + G + TAK++ G A+ D+
Sbjct: 5 GKRALVTGASKGLGAAVARRLAQAGADVAVHYHRDKAGAEETAKAVNASGRRALVLRADL 64
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+ +++ D +G LD L+N AGVA EQ + + +L G
Sbjct: 65 AVPGQAESVVELVRDAWGGLDLLVNNAGVAPVLPWDQVTPEQ------WAAVLAADLSGP 118
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F+V+R A+ L+ +G+ V+N SV +F+G AY+A+KAG+VG+T AR+
Sbjct: 119 FHVMRAALPLL------REGREPAVVNVGSVVSFNGGAFGPAYAAAKAGLVGLTRSAARE 172
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ--N 237
GIRV +APG +P+ LP PA+++++A P RLG E A +V ++
Sbjct: 173 WGPLGIRVNCVAPGPIDSPLARALPTPALEAMKAQTPL-RRLGTFGEVAEVVAWLLSPAA 231
Query: 238 PMLNGETIRLDG 249
+ G+T+ +DG
Sbjct: 232 AFVTGQTVVVDG 243
>UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 290
Score = 114 bits (274), Expect = 2e-24
Identities = 86/251 (34%), Positives = 123/251 (49%), Gaps = 16/251 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAV--FAPVDVTSED 63
V +VTGG+SG+G+A+ + G RVV D+ Q + + A F DV E
Sbjct: 9 VVVVTGGASGIGRASVLRFLAAGARVVFGDVNGATAQRLLDEVADPARLHFERADVADEA 68
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
+V + +++FGRLD + N AGV A F D+ + T V G F
Sbjct: 69 EVAALVAAAVERFGRLDVMFNNAGVGGA-----FGPLTDIDVADWDRTFGVISRGMFLGT 123
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ A A A G G +IN +SVA G G AYSA+KA V+ T A ++A
Sbjct: 124 KHAA-----RAMIAQGGGGSIINNSSVAGVGGGGGPTAYSAAKAAVINFTCNAAVELAAH 178
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASV-PFPSRLGHPQEFALLVQSII--QNPML 240
IRV I PGL TP++ E AI++ A+ P+P LG P++ A +V + + L
Sbjct: 179 RIRVNAICPGLVDTPLVMGRDEAAIRARMATFQPWPD-LGRPEDIAGIVLFLAGPDSAFL 237
Query: 241 NGETIRLDGSL 251
GE IR+DG +
Sbjct: 238 TGEAIRVDGGM 248
>UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR;
n=10; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
JLS)
Length = 282
Score = 114 bits (274), Expect = 2e-24
Identities = 68/199 (34%), Positives = 108/199 (54%), Gaps = 10/199 (5%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VA+VTGG+SG+G+ AE V +G +VVI D+ G+ A+ G NA+F DV +
Sbjct: 10 QGRVAIVTGGASGIGRGVAERFVAEGAKVVIADVQDELGEALAEQCGPNALFHHTDVGDQ 69
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ ++ + + +++FG LD ++N AG++S R F + DL F ++VNL+
Sbjct: 70 EQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNE----DLEEFDRVMRVNLLSVMAG 125
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
R A G+ + G G +IN +S+ G Y ASKA ++ T A ++A
Sbjct: 126 TRDA----GRYMSEHGG--GSIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAAIELAH 179
Query: 183 QGIRVVTIAPGLFRTPMME 201
IRV IAPG TP+++
Sbjct: 180 YDIRVNCIAPGNIPTPILQ 198
>UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=4; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 245
Score = 113 bits (273), Expect = 3e-24
Identities = 84/260 (32%), Positives = 128/260 (49%), Gaps = 23/260 (8%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQ----NTAKSLGENAVFAP 56
M + VA+VTG S G+G+A A L K+G VV+ S + + G A+
Sbjct: 1 MSETAVAIVTGASRGIGRAIALELAKEGATVVVNYARSAEAALEVVQRIEQQGGTAIAIA 60
Query: 57 VDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNL 116
DV+ + V + T++ +GR+D L+N AG+ + + E +Q I +NL
Sbjct: 61 ADVSVPEQVDTLVAKTVETYGRVDVLVNNAGITRDTLLLRMSLED------WQAVINLNL 114
Query: 117 IGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
G F R L+ K +RG +IN ASVA G GQA YSA+KAGV+G + +
Sbjct: 115 TGVFLCTRAVSKLMLKQ------KRGRIINIASVAGQMGNPGQANYSAAKAGVIGFSKTV 168
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
A+++A +GI V +APG T M +L I +P R G P E A +V+ +
Sbjct: 169 AKELASRGITVNAVAPGFIATEMTAELKAEDILKF---IPL-GRYGEPTEVAGMVRFLAL 224
Query: 237 NP---MLNGETIRLDGSLRM 253
+P + G+ +DG + M
Sbjct: 225 DPAAAYITGQVFNVDGGMVM 244
>UniRef50_Q46NA6 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR; n=1; Ralstonia eutropha
JMP134|Rep: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR - Ralstonia eutropha (strain
JMP134) (Alcaligenes eutrophus)
Length = 254
Score = 113 bits (273), Expect = 3e-24
Identities = 83/258 (32%), Positives = 121/258 (46%), Gaps = 22/258 (8%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VA+VTGG SG+GKA A G RVV+ D + A +G A A DV++E+
Sbjct: 12 GQVAVVTGGGSGIGKALAHTFAGAGARVVVLDTNGAAAEQVANEIGSMAQHAVADVSNEN 71
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNI--FQNTIQVNLIGTFN 121
++ ++ + GR+D L N AG+ ++ FDL I + + VN+ G F
Sbjct: 72 AIESVMEDVARQHGRIDVLFNNAGIN--------RRNTSFDLTIADWNAVVTVNMTGMFL 123
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFD-GQIGQAAYSASKAGVVGMTLPLARDM 180
R A + DG G ++NTAS+ G Y A+K VV MT A +
Sbjct: 124 CARAAARHM------RDGGGGRIVNTASILGISGGWYPNIVYQATKGAVVNMTRSWAVEW 177
Query: 181 AKQGIRVVTIAPGLFRTPMMEQL-PEP-AIKSLEASVPFPSRLGHPQEFA--LLVQSIIQ 236
A IRV +AP + RTPM E L +P + EA P RL P + +L +
Sbjct: 178 APYNIRVNAVAPSIIRTPMTEALTSQPDVVAKFEALTPL-GRLCEPADMTGPVLFLATAA 236
Query: 237 NPMLNGETIRLDGSLRMQ 254
+ M+ G + +DG + Q
Sbjct: 237 SSMVTGHILPIDGGVLAQ 254
>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
dehydrogenase/reductase family; n=1; Photobacterium
profundum|Rep: Hypothetical oxidoreductase, short-chain
dehydrogenase/reductase family - Photobacterium
profundum (Photobacterium sp. (strain SS9))
Length = 255
Score = 113 bits (272), Expect = 4e-24
Identities = 75/256 (29%), Positives = 128/256 (50%), Gaps = 19/256 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN--AVFAPVD 58
+ G VAL++G +SG+G+ATA L +QG +V+ KGQ A+ L +F D
Sbjct: 6 LLAGKVALISGITSGIGEATARLFSQQGASLVLVARNENKGQMLAEELNAQYPTLFIKAD 65
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
+T + V + + T+ +FG +D N AG+ + + + ++ I+ I NL G
Sbjct: 66 ITQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDE-----IWNQIINTNLNG 120
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
T+N++ + ++ K G ++N AS+ + + +AAY+ S+ V+G+T A
Sbjct: 121 TWNMLNRQLSIMSKQG------HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAAV 174
Query: 179 DMAKQGIRVVTIAPGLFRTPMME---QLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
+ AKQG+RV +APG TP+ E Q I + P R+G P+E A +
Sbjct: 175 EYAKQGVRVNAVAPGAIDTPIFERSTQKDPQLIAKYHQAHPI-GRIGQPREVAEAALWLC 233
Query: 236 Q--NPMLNGETIRLDG 249
+ + G T+ +DG
Sbjct: 234 SDLSSFVVGHTLMVDG 249
>UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2;
Bacteria|Rep: Short-chain dehydrogenase -
Symbiobacterium thermophilum
Length = 254
Score = 113 bits (272), Expect = 4e-24
Identities = 73/205 (35%), Positives = 107/205 (52%), Gaps = 13/205 (6%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
M G VA++TG + G+G ATAEL ++G RVVI DL G+ A+ + G A F
Sbjct: 3 MLDGKVAIITGAAMGMGAATAELFAREGARVVIADLNEELGRAQARKIQDAGGAAAFVRA 62
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+ DV+ +Q +D FGRLD +N A + +R D ++ I V+L
Sbjct: 63 DVSRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-----ADLDEAVWDAVIGVDLK 117
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G ++ + + K G G +IN +SV+ Q G AY A+K GV+G+T A
Sbjct: 118 GVALCLKYELRQMLKQ-----GGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAA 172
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQ 202
D + GIRV +APG TPM+++
Sbjct: 173 MDYSPHGIRVNAVAPGAVDTPMLQK 197
>UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;
Azoarcus sp. EbN1|Rep: Short-chain alcohol dehydrogenase
- Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 247
Score = 113 bits (272), Expect = 4e-24
Identities = 83/248 (33%), Positives = 127/248 (51%), Gaps = 16/248 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA-KSLGENAVFAPVDVTSEDD 64
+A+VTG +SG+G+ATA L K+G V D S A ++ G NA DV D
Sbjct: 7 IAIVTGAASGIGQATALRLAKEGAHVACFDFKSLDSTMKAIEAAGGNASAFQGDVKRASD 66
Query: 65 VKEALQITLDKFGRLDALINCAGVAS-ASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
E ++ T+++FGR+D L N AGV S S + E+ +D + +N+ GT+ +
Sbjct: 67 WAEMVKQTVERFGRVDVLANIAGVVSIGSDNILDQTEEGWD-----RIMDINVKGTWLGM 121
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ + ++ KN G ++N AS+AA G AAYSASK VV +T A + AK
Sbjct: 122 KEVMPVMMKNGG------GKIVNVASLAAHVGLTNLAAYSASKGAVVALTRYAAMEYAKD 175
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PMLN 241
I+V ++PG+ +TP++ K A P RLG P+E A +V + + +
Sbjct: 176 NIQVNAVSPGIIQTPILGDTTPEMTKLFSADTP-AGRLGRPEEIANMVLFLASDEADFIT 234
Query: 242 GETIRLDG 249
G T +DG
Sbjct: 235 GITHIVDG 242
>UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Methylobacterium
extorquens PA1
Length = 282
Score = 113 bits (272), Expect = 4e-24
Identities = 84/254 (33%), Positives = 128/254 (50%), Gaps = 19/254 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN--AVFA-PVD 58
F G VA +TG +SG+G+A A ++G +V I D + + N AV A D
Sbjct: 38 FNGKVAFITGAASGIGRAAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGAVIAIRCD 97
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVAS-ASRVYNFKKEQPFDLNIFQNTIQVNLI 117
V+ +DV A+ T+++FGRLD N AGV + A+ V+ ++ + + +NL
Sbjct: 98 VSLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALDE------WDRILDINLR 151
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
GTF ++ + + + GVV+NT+S A G G A+Y+ASK ++G+T A
Sbjct: 152 GTFVCMKHEIAQMLRQGG------GVVVNTSSGAGIRGVAGGASYAASKHALIGLTKSAA 205
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
D AK IRV + PG TPMME+ I+ P RLG P+E A V + +
Sbjct: 206 LDYAKANIRVNAVLPGNIETPMMERFTGGDIQKAIDLEPV-GRLGKPEEIAEAVLWMCSD 264
Query: 238 --PMLNGETIRLDG 249
+ G +I +DG
Sbjct: 265 LGAFVTGASISVDG 278
>UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34;
Proteobacteria|Rep: Acetoacetyl-CoA reductase -
Acinetobacter sp. (strain RA3849)
Length = 248
Score = 113 bits (272), Expect = 4e-24
Identities = 82/255 (32%), Positives = 124/255 (48%), Gaps = 20/255 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA--KSLG---ENAVFAPVDVT 60
VALVTG G+G LV G +++ +P + + +S G + F D+
Sbjct: 6 VALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLTDLN 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+ + A+Q + GR+D L+N AG+ +R FKK + I NL F
Sbjct: 66 NHEAATAAIQEAIAAEGRVDVLVNNAGI---TRDATFKK---MSYEQWSQVIDTNLKTLF 119
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
V + + + + G ++N +SV GQ GQA YSASKAG++G T LA++
Sbjct: 120 TVTQPVFNKM------LEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALAQEG 173
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNP 238
A+ I V +APG TPM+ + E IKS+EA +P RL P E A V ++
Sbjct: 174 ARSNICVNVVAPGYTATPMVTAMREDVIKSIEAQIPL-QRLAAPAEIAAAVMYLVSEHGA 232
Query: 239 MLNGETIRLDGSLRM 253
+ GET+ ++G L M
Sbjct: 233 YVTGETLSINGGLYM 247
>UniRef50_Q92506 Cluster: Estradiol 17-beta-dehydrogenase 8; n=38;
Euteleostomi|Rep: Estradiol 17-beta-dehydrogenase 8 -
Homo sapiens (Human)
Length = 261
Score = 113 bits (272), Expect = 4e-24
Identities = 77/264 (29%), Positives = 127/264 (48%), Gaps = 25/264 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE----------NA 52
+ +ALVTG SG+G+A + L +G V CDL Q T + LG N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 53 VFAPVDVTSEDDVKEALQITLDKFGRLDALI-NCAGVASASRVYNFKKEQPFDLNIFQNT 111
DV+ + L+ F R +++ +CAG+ + + ++ +
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD------WDKV 123
Query: 112 IQVNLIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVG 171
I VNL GTF V + A + N G RG +IN +S+ G +GQ Y+ASKAGV+G
Sbjct: 124 IAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178
Query: 172 MTLPLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLV 231
+T AR++ + GIR ++ PG TPM +++P+ + + +P LG P++ A +V
Sbjct: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVADVV 237
Query: 232 QSII--QNPMLNGETIRLDGSLRM 253
+ + + G ++ + G L M
Sbjct: 238 AFLASEDSGYITGTSVEVTGGLFM 261
>UniRef50_Q7W7A0 Cluster: Probable 3-oxoacyl-[acyl-carrier protein]
reductase; n=3; Bordetella|Rep: Probable
3-oxoacyl-[acyl-carrier protein] reductase - Bordetella
parapertussis
Length = 248
Score = 113 bits (271), Expect = 5e-24
Identities = 79/249 (31%), Positives = 125/249 (50%), Gaps = 16/249 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VALVTGG+ G+G A L +G R+V+ D+ + A SLGE A+ +DV
Sbjct: 7 QGRVALVTGGAGGIGLAVCRRLQAEGARIVVGDIGEERVLAAAASLGEGALGVFLDVADR 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
A + + ++D ++N AG+ + + + I VNL GT+
Sbjct: 67 QSWAAAKRAVDAQGWQVDIVVNVAGIVRDRSLAKMSDAE------WSAVIDVNLRGTWLG 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ A IG+ G +IN AS A F G GQA YSA+KAG+VG+T A + AK
Sbjct: 121 CQSAFAWIGERG------WGRIINVASTAIF-GAYGQANYSAAKAGIVGLTRTAALEGAK 173
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PML 240
+GI V +APG+ T ++ +P+ + A +P R P+E A ++ + + +
Sbjct: 174 RGILVNAVAPGIVETAILADVPDQVREGWLARMPL-KRTARPEEIAAVIAFLASDDASYM 232
Query: 241 NGETIRLDG 249
G+T+ +DG
Sbjct: 233 TGQTLVVDG 241
>UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=1; Bdellovibrio bacteriovorus|Rep:
3-oxoacyl-(Acyl carrier protein) reductase -
Bdellovibrio bacteriovorus
Length = 249
Score = 113 bits (271), Expect = 5e-24
Identities = 90/256 (35%), Positives = 130/256 (50%), Gaps = 22/256 (8%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKS----LGENAVFAPV 57
FK A+VTGG+SG+G + ++ GG V I D S TAKS G A V
Sbjct: 8 FKNKNAIVTGGASGIGFQITKSFLEAGGNVSIWDY-SEAALQTAKSEFAKYGSQIHIAQV 66
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV + D V +A +L +D L+N AG+ +R +F K P D + I NL
Sbjct: 67 DVGNRDSVAKAAA-SLP--WTVDILVNNAGI---TRDKSFAKMSPED---WDAVISTNLT 117
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G FNV + ++ K P+++ +R +IN ASV A G GQ Y A+KAGV+GM+ A
Sbjct: 118 GLFNVTK---SVLEKFNPNSNSKR--IINIASVVALYGNFGQTNYVAAKAGVIGMSKTWA 172
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA--LLVQSII 235
+++ ++G IAPG T M + +P + ++A VP + LG + A L S
Sbjct: 173 KELGRKGFTSNAIAPGFIATAMTKAMPAEVLDGMKAKVPV-ACLGEVDDIANTCLFLSSE 231
Query: 236 QNPMLNGETIRLDGSL 251
Q +NG I +DG L
Sbjct: 232 QAGYINGAVISVDGGL 247
>UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=2; Candidatus Pelagibacter ubique|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase -
Pelagibacter ubique
Length = 245
Score = 113 bits (271), Expect = 5e-24
Identities = 74/247 (29%), Positives = 125/247 (50%), Gaps = 17/247 (6%)
Query: 8 LVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDVKE 67
+VTG S G+G + E L + G ++ K + + N D++ D ++E
Sbjct: 10 IVTGASGGIGNSIVEKLNQNGANILATGTRIEKLEELKEKFN-NIKILKFDISQHDKIEE 68
Query: 68 ALQ-ITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRLA 126
++ T + G LD ++N AG+ + E+ + I +NL TF + + +
Sbjct: 69 FIENATKELGGSLDCIVNNAGITKDNLTIRMSLEE------WSKVININLTSTFLMCKYS 122
Query: 127 VGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGIR 186
+ + KN + G +IN SV G +GQA Y+ASKAG+V M+ LA + AK+ I
Sbjct: 123 IKKMLKN------KSGKIINITSVVGHTGNVGQANYTASKAGIVAMSKSLAIEYAKKNIN 176
Query: 187 VVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQ--SIIQNPMLNGET 244
V I+PG T M +Q+ E +++ A +P +RLG P++ A V S Q+ +NGET
Sbjct: 177 VNCISPGFISTAMTDQIDEKFKETIIAKIP-SNRLGKPEDIANAVNFLSSDQSDYINGET 235
Query: 245 IRLDGSL 251
+ ++G +
Sbjct: 236 LHVNGGM 242
>UniRef50_A4BPE5 Cluster: Acetoacetyl-CoA reductase; n=5;
Gammaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Nitrococcus mobilis Nb-231
Length = 248
Score = 113 bits (271), Expect = 5e-24
Identities = 81/253 (32%), Positives = 125/253 (49%), Gaps = 20/253 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVI-CDLPSTKG----QNTAKSLGENAVFAPVDVT 60
VALVTGG+ G+G + + L G RVV C P + + + LG + DV+
Sbjct: 5 VALVTGGNGGIGTSICQQLAGVGYRVVTTCVDPQKEAIASWRAVQRELGYEIHWVACDVS 64
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+ G++D ++N AG+ + ++ + E + I VNLI F
Sbjct: 65 DYGACVSMASELEAEHGKIDVIVNAAGITRDAFLHKMEPES------WNAVIDVNLISAF 118
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
NV R +G + + G +IN ASV GQ GQ YSA+KAG+ G T+ LA++
Sbjct: 119 NVTRQFIGSMRTR------EFGRIINIASVNGQTGQFGQTNYSAAKAGMHGFTMALAKES 172
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNP 238
A +GI V TI+PG RT M E +P+ ++ A +P R+G P E A + + +
Sbjct: 173 ALKGITVNTISPGYIRTSMTEAIPDKVRAAIVAQIP-AGRMGEPGEVARVAVFLASDDSQ 231
Query: 239 MLNGETIRLDGSL 251
+NG I ++G+L
Sbjct: 232 YINGANIPINGAL 244
>UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=1; Mycobacterium smegmatis str. MC2
155|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 236
Score = 113 bits (271), Expect = 5e-24
Identities = 81/246 (32%), Positives = 120/246 (48%), Gaps = 21/246 (8%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
VA++TG GLG+A A+ L K G +V+ P ++ T ++L P DVTSE DV
Sbjct: 5 VAVLTGADGGLGRAVAQRLAKDGFTLVLGYHPGSEAPQTPEALT-----VPADVTSEHDV 59
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ + ++GR+DAL+ AGV + + + DL + TI VNL GTF +
Sbjct: 60 AKLTSAAVIEYGRIDALVTLAGVMEQTLLPDL------DLATWNQTIAVNLTGTFLCAKA 113
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
A + K G ++ S + G I AAY+ASKAGV G+T LAR++ +
Sbjct: 114 AADELMKTG-------GTIVTIGSQIGYVGGINCAAYTASKAGVAGLTRALARELGPT-V 165
Query: 186 RVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPMLNGE 243
RV +APG TPM P + R G P E A V ++ + + G+
Sbjct: 166 RVNCVAPGPIETPMTAVHATPEWVEQKTRSLVMGRFGTPDEVATAVSWLVGDEASFVTGQ 225
Query: 244 TIRLDG 249
TI ++G
Sbjct: 226 TINVNG 231
>UniRef50_Q8WTW8 Cluster: Carbonyl reductase 4; n=25;
Euteleostomi|Rep: Carbonyl reductase 4 - Homo sapiens
(Human)
Length = 237
Score = 113 bits (271), Expect = 5e-24
Identities = 72/248 (29%), Positives = 124/248 (50%), Gaps = 16/248 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
V V GGS G+G+A A+L+ ++G R+ + + A LG + + DV E DV
Sbjct: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ + GR++ L+N AG+ + K E + + NL+G+ +
Sbjct: 64 QNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTED------MVSQLHTNLLGSMLTCKA 117
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
A+ + + Q G ++N S+ G GQ+ YSASK G+VG + LA+++A++ I
Sbjct: 118 AMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171
Query: 186 RVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNGETI 245
RV +APG T M + L E + L+ ++P R G E A V ++++P + G +
Sbjct: 172 RVNVVAPGFVHTDMTKDLKE---EHLKKNIPL-GRFGETIEVAHAVVFLLESPYITGHVL 227
Query: 246 RLDGSLRM 253
+DG L++
Sbjct: 228 VVDGGLQL 235
>UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase family
oxidoreductase, putative; n=3; Pezizomycotina|Rep: Short
chain dehydrogenase/reductase family oxidoreductase,
putative - Aspergillus clavatus
Length = 249
Score = 113 bits (271), Expect = 5e-24
Identities = 83/253 (32%), Positives = 127/253 (50%), Gaps = 17/253 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPST-KGQNTAKSLG-ENAVFAPVDVTS 61
G VALVTG S G+G+ATA L K G VV+ + S + +G E+A+ DV+
Sbjct: 6 GKVALVTGASRGIGRATALALAKDGANVVVNYIASAASAEQVVSEIGREHAIAVQADVSK 65
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+D+ ++ T+D+FG++D L+ AG+ EQ FD N
Sbjct: 66 REDIARLVKTTVDRFGKIDVLVLNAGLLWQKGDLLSITEQDFDTLFAAN----------- 114
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQI-GQAAYSASKAGVVGMTLPLARDM 180
+R + I + AP V++ + S+AAF G Y+ASK V MT LA+D+
Sbjct: 115 -VRSPLFTIQEAAPHLTEGGRVMLFSTSLAAFSGVTPNYLLYAASKGAVEQMTRVLAKDL 173
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNP 238
++GI V TIAPG T + L++++ RLG P+E A +V I Q+
Sbjct: 174 GRRGITVNTIAPGPIGTDAYFVGNNEQMVQLQSNLAPTGRLGKPEEVAAVVNFIASDQSQ 233
Query: 239 MLNGETIRLDGSL 251
+NG+TIR++G +
Sbjct: 234 WVNGQTIRINGDM 246
>UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=1;
Oceanobacter sp. RED65|Rep: Putative fatty acyl chain
reductase - Oceanobacter sp. RED65
Length = 252
Score = 112 bits (270), Expect = 7e-24
Identities = 76/258 (29%), Positives = 132/258 (51%), Gaps = 19/258 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFA--PV--D 58
+G + L+TGGS LG+A+ KQ RV S + + E + F P+ +
Sbjct: 8 EGKIVLITGGSGDLGRASVLEFGKQKCRVYFTYNSSKDSADELVASAEESGFEAFPIRCN 67
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
++ ++ V + ++K G++D L+N AG+ + + E+ F+ IQ NL G
Sbjct: 68 ISDKEQVNALVNDIVEKEGKIDVLVNNAGIYKDNLFTSMTDEE------FEQVIQTNLYG 121
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
TF + V ++ +N + G ++N +S+A GQA YSA+K VV + LA
Sbjct: 122 TFYCTKSVVDVMYRN------RCGAIVNVSSIAGVTNSFGQANYSAAKGAVVSFSRTLAA 175
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--Q 236
++A + IRV T+APGL + M++++P +K + +P RLG P+E A + +
Sbjct: 176 ELAPKNIRVNTVAPGLIDSSMVKRIPRNIMKQTLSGIPV-KRLGKPEEIAKAIAFLASED 234
Query: 237 NPMLNGETIRLDGSLRMQ 254
+ + G+T+ DG L M+
Sbjct: 235 SSYVVGQTLIADGGLIMR 252
>UniRef50_Q1AU84 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
16129)
Length = 249
Score = 112 bits (270), Expect = 7e-24
Identities = 81/255 (31%), Positives = 126/255 (49%), Gaps = 20/255 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAK---SLGENAVFAPV 57
M +G VA++TG SG+G+ATA ++G RVV +L G+ + SLG AVF
Sbjct: 1 MLEGKVAVITGAGSGIGRATALKFAREGARVVAAELDERGGEGVVREVRSLGGEAVFVRT 60
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+ V++A++ + ++G LD + N AG+ + + + E + ++VN
Sbjct: 61 DVSEFAQVEDAVERAVGEYGTLDVMFNNAGIGHYAPLLEHEPEH------YDRVVRVNQY 114
Query: 118 GTFNVIRLAVG--LIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
G + I LA G ++ P G++INTASV AF G Y A+K V MT
Sbjct: 115 GVYYGI-LAAGRKMVALKNP------GLIINTASVYAFLASPGVIGYHAAKGAVKMMTQA 167
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
A ++A GIRVV IAPG TP+++ + + A RL P++ A V +
Sbjct: 168 AALELAPHGIRVVAIAPGGVDTPIIQGYKDMGLGERLARGQMRRRLQTPEQIAGAVALLA 227
Query: 236 --QNPMLNGETIRLD 248
+ +NG + D
Sbjct: 228 TDEADAINGSVVMTD 242
>UniRef50_Q1ASH3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
16129)
Length = 243
Score = 112 bits (270), Expect = 7e-24
Identities = 77/226 (34%), Positives = 112/226 (49%), Gaps = 16/226 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDVTSE 62
V LVTG SG+G+A AE K RVV+ D+ + A + LG ++ AP DV+
Sbjct: 3 VVLVTGAGSGIGRAIAERFAKDEERVVVNDIREEAAEQVASHIRRLGGESIAAPGDVSDP 62
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ VK + + + +G D L+N AG R + E F I V+L GTF
Sbjct: 63 EAVKNIVNVCGEAYGHPDVLVNNAGFVQQKRFVDLSVED------FDRMIAVHLRGTFLC 116
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
IR + + G+V+N AS G I YSA+KAG++G+T LAR+++
Sbjct: 117 IREVLPEMLTRG------YGIVVNIASQLGQIGGIELCHYSAAKAGIIGLTKALAREVSA 170
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA 228
QG+RV +APG T ++ L E ++ A +P R G P E A
Sbjct: 171 QGVRVNAVAPGPINTELVRGLSEEWRRTKAAELPL-GRFGEPWEVA 215
>UniRef50_A0PWM6 Cluster: Short-chain type dehydrogenase/reductase;
n=1; Mycobacterium ulcerans Agy99|Rep: Short-chain type
dehydrogenase/reductase - Mycobacterium ulcerans (strain
Agy99)
Length = 268
Score = 112 bits (270), Expect = 7e-24
Identities = 79/249 (31%), Positives = 121/249 (48%), Gaps = 14/249 (5%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
VA++TG G+G T+ + G RVV+ DLP T A S+G AV VD+T+E V
Sbjct: 9 VAIITGACGGIGLETSRVPACAGARVVLADLPETDLAGAAASVGRGAVHHVVDLTNEVSV 68
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ + T+D FGRLD + N A + + + ++++ +T VN GT + +
Sbjct: 69 RALIDFTIDTFGRLDIVDNNAAHSDPADML----VSQMTVDVWDDTFTVNARGTMLMCKY 124
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
A+ A G G ++N +S A AYS +KA + +T +A + G+
Sbjct: 125 AI----PRLISAGG--GAIVNISSATAHAAYDMSTAYSCTKAAIETLTRYVATQYGRHGV 178
Query: 186 RVVTIAPGLFRTPMME-QLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PMLNG 242
R IAPGL RTP +E LP+P I + A+ +G P E A LV + + + G
Sbjct: 179 RCNAIAPGLVRTPRLEVGLPQP-IVDIFATHHLAGLIGEPHEIAELVCFLASDRAAFITG 237
Query: 243 ETIRLDGSL 251
+ I D L
Sbjct: 238 QVIAADSGL 246
>UniRef50_Q0V6D8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 267
Score = 112 bits (270), Expect = 7e-24
Identities = 80/262 (30%), Positives = 131/262 (50%), Gaps = 17/262 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDL-PSTKGQNTA-----KSLGENAVFAPVDV 59
VA+VTG S G+G+ +G +V DL P KG++ A G ++F DV
Sbjct: 10 VAIVTGSSQGIGREICNQFFLEGAILVCADLRPLGKGESIATHDWISQRGGKSIFVETDV 69
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T + + + T++ +G+LD ++ AG+ + + N + D ++F +++N G
Sbjct: 70 TIAESWRGLIAKTVETYGKLDIVVGNAGICTEAG--NPQPIHEVDEDVFDAHMRINARGV 127
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F + V K P A+G RG ++N AS+ + G G Y+ASK V MT +A D
Sbjct: 128 FLGSKYCVQQFLKQEPRANGIRGWIVNLASMVSNIGMPGLTGYTASKGAVAAMTRTIALD 187
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQ-----LPEPAIKSLEASVPFPSRLGHPQEFALLVQSI 234
+AK+GI IAPG +T M++ LP A++ ++AS+P GHP + A +
Sbjct: 188 VAKEGIVANCIAPGFSQTAMLDDALGGALP-GAVEGIKASIP-RGIFGHPLDHARAAVYL 245
Query: 235 IQN--PMLNGETIRLDGSLRMQ 254
+ + G T+ +DG L Q
Sbjct: 246 ASDDAQWITGITLNVDGGLVAQ 267
>UniRef50_Q0U4L0 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 274
Score = 112 bits (270), Expect = 7e-24
Identities = 73/237 (30%), Positives = 119/237 (50%), Gaps = 15/237 (6%)
Query: 7 ALVTGGSSGLGKATAELLVKQGGRVVICDLPST----------KGQNTAK--SLGENAVF 54
A++TG SSG+G+A A L +G +V D+ T G + +LG A++
Sbjct: 10 AIITGSSSGIGRAIALALASEGANIVCSDITETFRPEYRTDSLSGTTLQEVTNLGVRAIY 69
Query: 55 APVDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQV 114
D TS +V+ ++ + +FGR+D ++N AG+A + + + D F+ T+++
Sbjct: 70 QKCDTTSSAEVESLVKRAVQEFGRVDIMVNNAGIAVETGEHGNRPIWDVDEEAFERTMRI 129
Query: 115 NLIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTL 174
N+ G F ++ A + P +G RG +IN ASV G G ++Y SK V+G+T
Sbjct: 130 NVRGVFLGVKYASRQMKDQEPGTNGDRGWIINLASVYGLGGGEGASSYITSKHAVMGITK 189
Query: 175 PLARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASV--PFPSR-LGHPQEFA 228
A D A I V + PG +T + L P ++++A V P R LG PQ+ A
Sbjct: 190 AAAHDCAPLRIHVNALCPGFVQTSFIAGLLSPEAEAVKAEVMKKHPFRGLGTPQDVA 246
>UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
16129)
Length = 256
Score = 112 bits (269), Expect = 9e-24
Identities = 84/252 (33%), Positives = 123/252 (48%), Gaps = 15/252 (5%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDVTSE 62
VA++TG +SG G+A A+L +G +VV D+ Q T K G A VDV+ E
Sbjct: 7 VAVITGAASGQGRAAAKLFASEGAKVVAADIDEGGAQRTVEEIKEAGGEATAVKVDVSRE 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVA-SASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
DV+ ++ D++GRLD L N AGV SAS + + +NL G
Sbjct: 67 PDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINLKGVAL 126
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ A+ ++ + G +IN AS+ A G G AY+A+K GVV + LA +
Sbjct: 127 GCKHAIPVMERQG------YGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLAVEWG 180
Query: 182 KQGIRVVTIAPGLFRTPMMEQL--PEPAIKSLEASVPFPSRLGHPQEFA--LLVQSIIQN 237
+GIRV I PG TPM+ + E ++S+ + P RL P+E A L + +
Sbjct: 181 PRGIRVNCICPGGVDTPMIAPVISDERVMQSMRQNTPL-GRLARPEEIASVALFLASEEA 239
Query: 238 PMLNGETIRLDG 249
LNG I +DG
Sbjct: 240 SYLNGAIIPVDG 251
>UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=32; cellular organisms|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Methanosarcina acetivorans
Length = 256
Score = 112 bits (269), Expect = 9e-24
Identities = 83/256 (32%), Positives = 125/256 (48%), Gaps = 21/256 (8%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAK--SLGENAVFAPVDV 59
F G VA VTGG++G+G+ATA ++G V + Q + LG A+ DV
Sbjct: 9 FLGKVAFVTGGATGIGQATAVAFAREGANVALTYHNQGAEQTVRRIEELGGQALAIKCDV 68
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
E+DVK A++ + FG+LD N AG+ + + E P + + I NL G
Sbjct: 69 IREEDVKNAIEKIIQTFGQLDYAFNNAGIEGKTVI---TAEYPVEE--WNRVIATNLTGV 123
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F ++ + + K G ++N +S A G + Y ASK GVVG+T A D
Sbjct: 124 FLCMKYEIPQMLKQGA------GAIVNCSSGAGLTGFPDISPYVASKHGVVGLTKTAALD 177
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQ----LPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
AK IR+ + PG+ TPMME+ PE K +E P R+G P+E A+ V +
Sbjct: 178 YAKSNIRINAVCPGMTDTPMMERYSGGTPEGYEKIIEQE-PI-GRMGRPEEIAIAVLWLC 235
Query: 236 QN--PMLNGETIRLDG 249
+ + G+ +R+DG
Sbjct: 236 SDAASFVTGDVMRVDG 251
>UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Short chain
dehydrogenase - Hyperthermus butylicus (strain DSM 5456
/ JCM 9403)
Length = 243
Score = 112 bits (269), Expect = 9e-24
Identities = 74/254 (29%), Positives = 132/254 (51%), Gaps = 20/254 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTK--GQNTA---KSLGENAVFAPV 57
+G V LVTG S G+G+A A ++G + V+ + S + + TA K G +
Sbjct: 4 QGSVVLVTGSSRGIGRAVAVEAARRGAKGVVVNYVSRRDAAEETARLVKEAGAVPLVVRA 63
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+ ++ ++ ++ ++K+GRLD ++N AG+ F+ +P D +Q I+V+
Sbjct: 64 DVSVYEEARKLVEAAIEKWGRLDVVVNNAGILEPKL---FEDMKPRD---WQRMIEVHFY 117
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G NV A+ + +N GV++N ASV + + YSA+KA ++ T+ +A
Sbjct: 118 GALNVAHAAIPYMKRNGG------GVIVNIASVLGLRPEPEASHYSAAKAALIAWTIAVA 171
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
+++A IRV +APG T M + + +E +P RL P+E A +V ++N
Sbjct: 172 KELADYNIRVFAVAPGGVDTDMTRAWGD--MDWVEEQIPL-RRLAKPEEVAKIVLDAVEN 228
Query: 238 PMLNGETIRLDGSL 251
P ++G+ + + G L
Sbjct: 229 PYVSGDVLTISGGL 242
>UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=8; root|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Pseudomonas paucimobilis (Sphingomonas paucimobilis)
Length = 250
Score = 112 bits (269), Expect = 9e-24
Identities = 68/199 (34%), Positives = 97/199 (48%), Gaps = 10/199 (5%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G +VTGG SG+G+AT ELLV G V + D+ G+ + G A + D+ E+
Sbjct: 6 GKTIIVTGGGSGIGRATVELLVASGANVPVADINDEAGEAVVATSGGKAAYFRCDIAQEE 65
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
DVK + TL FG LD N A + A L F+ ++ +N+ GTF +
Sbjct: 66 DVKALVAQTLAAFGGLDGSFNNAAIPQAGLPL-----AEVSLERFRQSMDINVTGTFLCM 120
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ + A G +G ++NTAS A G Y +K VVG+T A D K
Sbjct: 121 KYQI-----LAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAAADYGKH 175
Query: 184 GIRVVTIAPGLFRTPMMEQ 202
GIRV + PG RTPM+++
Sbjct: 176 GIRVNALVPGAVRTPMLQR 194
>UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=3; Gammaproteobacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Buchnera
aphidicola subsp. Baizongia pistaciae
Length = 245
Score = 112 bits (269), Expect = 9e-24
Identities = 77/251 (30%), Positives = 123/251 (49%), Gaps = 16/251 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA-KSLGENAVFAPVDVTSEDD 64
+A++TG + GLGK AE L VI S KG K L N + +D+T+ ++
Sbjct: 7 IAVITGANRGLGKGIAEELSNTNNITVIGTSTSQKGCKIINKYLKNNGIGIKLDITNPNE 66
Query: 65 VKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIR 124
+ + + FGR+D LIN AG+ + N K + + + + VNL F + +
Sbjct: 67 ITKTMDFVYKNFGRVDILINNAGIIRDKLLINMKTQD------WNSVLNVNLNSIFYMSK 120
Query: 125 LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
+ + KN ++G +I SV A G GQ YSA+K G+VG LA ++A +G
Sbjct: 121 SVIRNMIKN------KQGKIITIGSVIAHIGNCGQTNYSAAKLGLVGFHKSLALELAPKG 174
Query: 185 IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP--MLNG 242
I V IAPGL +T M L + + + +P RLG +E + + +I N + G
Sbjct: 175 ITVNMIAPGLIKTGMTNNLSQKQLSKYLSKIPM-KRLGTIKEISKITLFLISNDANYITG 233
Query: 243 ETIRLDGSLRM 253
+ I ++G + M
Sbjct: 234 QVIHVNGGMYM 244
>UniRef50_Q6MLJ7 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
reductase; n=3; Bacteria|Rep:
3-oxoacyl-(Acyl-carrier-protein) reductase -
Bdellovibrio bacteriovorus
Length = 256
Score = 111 bits (268), Expect = 1e-23
Identities = 70/255 (27%), Positives = 123/255 (48%), Gaps = 17/255 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVIC-DLPSTKGQNTAKSL-GENAVFAPVDVT 60
+G +VTGGS G+G A +LL +G +V Q A SL GE + +D+
Sbjct: 14 QGKKIVVTGGSRGIGAAIVKLLADEGAQVAFTYSSREEAAQQVAHSLTGEGHFYIKMDIA 73
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+E+ V A+ L+K+ +D ++N AG+ + K E F + + NL GTF
Sbjct: 74 NEESVNSAVDHILEKWSDIDGVVNNAGITKDGLLLRMKSED------FDSVVNTNLRGTF 127
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
V + P ++G ++N S+ G GQA Y+ASKAG + + +A ++
Sbjct: 128 LVTKAFT------KPMMKARKGSIVNIVSIIGETGNAGQANYAASKAGTIAFSKSVALEL 181
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNP 238
+ +RV +APG T M + L E + +P +++G + A V+ ++ ++
Sbjct: 182 GSRNVRVNNVAPGYIATEMTDVLSEDVKSKMMEKIPL-AKIGEGSDVAQAVRFLLSDESK 240
Query: 239 MLNGETIRLDGSLRM 253
+ G T+ ++G + M
Sbjct: 241 YITGHTLDVNGGMHM 255
>UniRef50_Q53WH2 Cluster: 3-oxoacyl-[acyl carrier protein]
reductase; n=4; Thermus thermophilus|Rep:
3-oxoacyl-[acyl carrier protein] reductase - Thermus
thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length = 263
Score = 111 bits (268), Expect = 1e-23
Identities = 75/248 (30%), Positives = 124/248 (50%), Gaps = 18/248 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G LVTG +SG+G+A +L ++G +V D +L A+ DV+
Sbjct: 6 GKTILVTGAASGIGRAALDLFAREGASLVAVDREERLLAEAVAALEAEAIAVVADVSDPK 65
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
V+ L++FGRL + + AGVA ++ +N L ++ ++VNL G+F
Sbjct: 66 AVEAVFAEALEEFGRLHGVAHFAGVAHSALSWN------LPLEAWEKVLRVNLTGSF--- 116
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
L+ + A + + G ++ T SVA G G A Y+A K GVVG+ LA ++A++
Sbjct: 117 -----LVARKAGEVLEEGGSLVLTGSVAGL-GAFGLAHYAAGKLGVVGLARTLALELARK 170
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPMLN 241
G+RV + PGL +TPM LP A + + P R G P+E A ++ ++ +
Sbjct: 171 GVRVNVLLPGLIQTPMTAGLPPWAWEQEVGASPL-GRAGRPEEVAQAALFLLSEESAYIT 229
Query: 242 GETIRLDG 249
G+ + +DG
Sbjct: 230 GQALYVDG 237
>UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Roseiflexus|Rep: Short-chain
dehydrogenase/reductase SDR - Roseiflexus sp. RS-1
Length = 248
Score = 111 bits (268), Expect = 1e-23
Identities = 82/255 (32%), Positives = 126/255 (49%), Gaps = 18/255 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
MF V ++TGG SG+G+ATA + G RVVI + ++ G+ T ++ G A+F P
Sbjct: 1 MFNESVVVITGGGSGIGRATALAFGRHGARVVIGNRNASTGEETVAAIRATGGTALFVPT 60
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DVT V+ + T+ FGRLD N AG + E+ FD N+
Sbjct: 61 DVTQPVAVRALIDTTVATFGRLDIAFNNAGWFGPVAPLADQDEREFD-----PVFDTNVR 115
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVA-AFDGQIGQAAYSASKAGVVGMTLPL 176
GTF ++ + + K GQ G++IN AS A + +G A Y+A+KA V+ +T
Sbjct: 116 GTFLCMKYELAQMLKQ-----GQ-GIIINNASTTGARNSTVGVALYAAAKAAVISLTRSA 169
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
A + A QG+R+ +APG T M+ + + A +P RLG P+E A V +
Sbjct: 170 AMEYAAQGVRINAVAPGRIATGMLAKAGGGNPERFAAVIPM-RRLGTPEEVAEAVLWLAS 228
Query: 237 --NPMLNGETIRLDG 249
+ G+ + +DG
Sbjct: 229 PAASFVTGQVLGVDG 243
>UniRef50_A4XF74 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Novosphingobium aromaticivorans DSM 12444|Rep:
Short-chain dehydrogenase/reductase SDR -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 252
Score = 111 bits (268), Expect = 1e-23
Identities = 77/252 (30%), Positives = 127/252 (50%), Gaps = 14/252 (5%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G V LVTGG SG+G AT LL K G +V++ D + + A + A VDV
Sbjct: 5 GKVILVTGGGSGIGAATCRLLGKAGAQVIVADRAGARAEAVAADI-PGAWGVVVDVVDAA 63
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYN--FKKEQPFDLNIFQNTIQVNLIGTFN 121
+ ++ ++FGRLD N AG+ + + + L +++ + V+L G FN
Sbjct: 64 ACEAMVEGIRERFGRLDGAFNNAGITEVTALGGAPIPETHALPLEVWRKVLSVDLDGVFN 123
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+R + L+ A G G ++NT S+ A AAY+A+K GV+G+T +A++
Sbjct: 124 CLRAEIPLML-----ASGG-GAIVNTTSLQAHISYPRTAAYTAAKHGVLGLTKAIAKEYG 177
Query: 182 KQGIRVVTIAPGLFRTPMME-QLPEPAIKS-LEASVPFPSRLGHPQEFALLVQSII--QN 237
+QGIR +++PG+ TP+ + P K L A +P R P++ A ++ ++
Sbjct: 178 EQGIRCNSVSPGVVDTPLTAGVIHSPQYKDMLLAPIPL-KRFATPEDIAKAALWLLSDES 236
Query: 238 PMLNGETIRLDG 249
+NG T+ DG
Sbjct: 237 AYINGATLAADG 248
>UniRef50_A3ZUW7 Cluster: Putative oxidoreductase; n=1;
Blastopirellula marina DSM 3645|Rep: Putative
oxidoreductase - Blastopirellula marina DSM 3645
Length = 261
Score = 111 bits (268), Expect = 1e-23
Identities = 83/254 (32%), Positives = 125/254 (49%), Gaps = 19/254 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDV 59
+G A+V G + LG A AE L + G VV+ + +G A + LG A+F PVD
Sbjct: 13 EGRTAIVIGATGVLGGAIAEGLAQAGANVVVSGMNEGRGSAQAVRIQELGGEAIFQPVDA 72
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
S + + +TL+KFG +D L+NCAGV ++S Y E+ +D I NL GT
Sbjct: 73 VSRASLTKLKDVTLEKFGSIDMLVNCAGV-NSSVPYEEITEEDWD-----RVIATNLTGT 126
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
++ L+ + PD G ++N SV A AYSASKA VV ++ +AR+
Sbjct: 127 HLACQIFAPLMAEQ-PDG----GSILNIGSVTAHLPLSRVYAYSASKAAVVNLSQNVARE 181
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQ-LPEPAIKSLEASVPFPSRLGHPQEF---ALLVQSII 235
A + +RV + PG F + L + + ++ A P R G P+E A+ + S
Sbjct: 182 YATRKVRVNVLCPGFFPAEQNRKILDQDRVSNIMAQTPM-KRFGEPEELVGAAITLLSPK 240
Query: 236 QNPMLNGETIRLDG 249
+ G TI +DG
Sbjct: 241 AGSFITGATIYVDG 254
>UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=123; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia
conorii
Length = 241
Score = 111 bits (268), Expect = 1e-23
Identities = 80/252 (31%), Positives = 128/252 (50%), Gaps = 19/252 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G +L+TG S G+G A A LL K G V+I K Q+ K + +N ++V +
Sbjct: 6 GKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLQSLGKVVKDNYT---IEVCNLA 62
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
D KE + + K +LD L+ AG+ S + K E F I +NL F +
Sbjct: 63 D-KEECRNLISKASKLDILVCNAGITSDTLAIRMKDED------FDKVIDINLKANFILN 115
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
R A+ + +N + G +IN +S+ G GQA Y ASKAG++GMT L+ ++A +
Sbjct: 116 REAIKKMIQN------RYGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLSYEVATR 169
Query: 184 GIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPMLN 241
GI V T+APG ++ M ++L E +++ +P G P++ A V + Q +
Sbjct: 170 GITVNTVAPGFIKSDMTDKLNEKQREAIVQKIPL-GTYGMPEDVAHAVAFLASDQASYIT 228
Query: 242 GETIRLDGSLRM 253
G+TI ++G + M
Sbjct: 229 GQTIHVNGGMLM 240
>UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1;
Zymomonas mobilis|Rep: Putative uncharacterized protein
- Zymomonas mobilis
Length = 254
Score = 111 bits (267), Expect = 2e-23
Identities = 75/233 (32%), Positives = 114/233 (48%), Gaps = 18/233 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAK---SLGENAVFAPVD 58
+ G VALVTG +G+G+ TA K V I Q T + +G A+ D
Sbjct: 7 YSGKVALVTGAGTGIGRETALAFAKAKAYVAIIGRSENNIQETLRLVTEMGGQAIAIQAD 66
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVA-SASRVYNFKKEQPFDLNIFQNTIQVNLI 117
V+ ED +K A++ T++ FG+LD N AG+ A + E+ + I NL
Sbjct: 67 VSQEDSIKAAIEKTVETFGKLDFAFNNAGIEHKAIPAADIPSEE------WDRIISTNLN 120
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G F ++ + + K+ G ++NTAS A G G AY ASK G++G++ A
Sbjct: 121 GVFFSMKHEIPAMLKSGS------GSIVNTASGAGVKGFPGNGAYCASKFGLIGLSKAAA 174
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFP--SRLGHPQEFA 228
D AKQ +R+ +APG+ TPMM++ + E ++ R GHP+E A
Sbjct: 175 LDYAKQHLRINVVAPGIIETPMMQRFTGGTEEGRETAIAQEPVGRAGHPKEIA 227
>UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7;
Vibrio|Rep: Acetoacetyl-CoA reductase - Vibrio
parahaemolyticus
Length = 246
Score = 111 bits (267), Expect = 2e-23
Identities = 83/256 (32%), Positives = 126/256 (49%), Gaps = 22/256 (8%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPST-----KGQNTAKSLGENAVFAPVDVT 60
VAL+TG G+G A + LV G RV+ + N+ + +DVT
Sbjct: 4 VALITGSKGGIGSAISSQLVNDGYRVIATYFTGNYECALEWFNSKGFTKDQVRLFELDVT 63
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+ + E L L++ G +D ++N AG+ +R FKK + + I NL F
Sbjct: 64 NTAECAEKLAQLLEEEGTIDVVVNNAGI---TRDGVFKK---MTAQAWNDVINTNLNSLF 117
Query: 121 NVIR-LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
NV + L + K G VIN +SV GQ GQA YSA+KAG++G + LA +
Sbjct: 118 NVTQPLFAAMCEKGG-------GRVINISSVNGLKGQFGQANYSAAKAGMIGFSKALAYE 170
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN-- 237
A+ G+ V IAPG TPM+EQ+ ++S+ +P RL P+E A V ++ +
Sbjct: 171 GARSGVTVNVIAPGYTGTPMVEQMKPEVLESITNQIPM-KRLATPEEIAASVSFLVSDAG 229
Query: 238 PMLNGETIRLDGSLRM 253
+ GET+ ++G L M
Sbjct: 230 AYITGETLSVNGGLYM 245
>UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
dehydrogenase/reductase SDR - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 251
Score = 111 bits (267), Expect = 2e-23
Identities = 73/234 (31%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G +VTG SG+G+A A +G RV + D+ + A +GE + DVT
Sbjct: 5 EGKRTIVTGAGSGIGRAIALRFAAEGARVALADVDEGAARKVAAEIGEGCLVQRTDVTVA 64
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
++V+ +++ +++G L+ ++N AGV A+ +E F+ + VNL GTF
Sbjct: 65 EEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEED------FERVLAVNLRGTFLG 118
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
++ A+ I D G VIN +S+AA G +AAYSA+K G++ +T A D
Sbjct: 119 MKYAIPAI------RDSGGGAVINMSSIAALVGLKDRAAYSAAKGGILALTRAGAIDHIH 172
Query: 183 QGIRVVTIAPGLFRTPMMEQL------PEPAIKSLEASVPFPSRLGHPQEFALL 230
+G+RV IAPG TP + ++ PE A + + P R P+E A +
Sbjct: 173 EGVRVNCIAPGTVETPWISRITAGYADPEEARRRMRERQPH-GRFVRPEEVAAM 225
>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Hyphomonas
neptunium ATCC 15444|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Hyphomonas neptunium
(strain ATCC 15444)
Length = 262
Score = 111 bits (267), Expect = 2e-23
Identities = 73/233 (31%), Positives = 121/233 (51%), Gaps = 19/233 (8%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTS 61
F+ VA++TG +SG+G ATA LL ++G VV+ D+ G++ A LG A+ DV+S
Sbjct: 6 FENKVAVITGAASGIGAATARLLAREGAHVVLADVNDNGGKSIAADLGPTAMAVKCDVSS 65
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+V+ ++ +++ GR+D L N AG+ S QP + ++ I ++L +
Sbjct: 66 AAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEI---QPAE---WERVIAIDLHSVYY 119
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
A+ + + + ++NTAS++ G AAY+A+K VV T LA D
Sbjct: 120 ACHFAIPHMPRGS--------AIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALAVDHG 171
Query: 182 KQGIRVVTIAPGLFRTPM---MEQLPEPAIKSLEASVPFPSRLGHPQEFALLV 231
+ GIRV + PGL TP+ ++Q+P L+ +P R P+E A +V
Sbjct: 172 RDGIRVNALCPGLVETPITAGVQQMPGLREDWLK-RIPM-ERAAQPEEMASVV 222
>UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=11; Bacteria|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Xylella fastidiosa
Length = 255
Score = 111 bits (266), Expect = 2e-23
Identities = 82/256 (32%), Positives = 123/256 (48%), Gaps = 20/256 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVD 58
FKG VALVTG ++G+G ATA + G VV+ D + A ++ G A+ D
Sbjct: 7 FKGQVALVTGAAAGMGLATARGFAQGGASVVLADRDGERAAQEAAAIVAEGGTAIGLACD 66
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ E V ++ T+ ++GRLD N AGV + + + FD I +NL G
Sbjct: 67 VSDEAQVAALVEKTVAEYGRLDFAFNNAGVMAKIAPFAEATSEEFD-----RVIGINLRG 121
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
+ ++ + + + GV++N ASV A G +G AY ASK GV+G+T A
Sbjct: 122 VWLCMKYELQQMQRQGS------GVIVNNASVGALTGNVGIGAYIASKHGVLGLTRAAAL 175
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQL---PEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
+ K+GIRV + PG T + + + A L AS P R G P+E A V +
Sbjct: 176 EYCKKGIRVNAVNPGTIDTQIARDVVGGSDEAFAKLGASAPI-GRAGRPEEIASAVLWLC 234
Query: 236 Q--NPMLNGETIRLDG 249
+ GE + +DG
Sbjct: 235 SPGGSYVIGEGLTVDG 250
>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caulobacter sp. K31|Rep: Short-chain
dehydrogenase/reductase SDR - Caulobacter sp. K31
Length = 277
Score = 111 bits (266), Expect = 2e-23
Identities = 89/261 (34%), Positives = 128/261 (49%), Gaps = 22/261 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G +A+VTG + GLG A A+ +++G VV+ DL K A LG A DV
Sbjct: 7 QGKIAIVTGAARGLGAAIAKRYLEEGATVVLADLSEEKTTERAAELGAGAHGRRCDVGDW 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ + T+ +FGRLD L+N AG+ A V F + DL ++VN+ F
Sbjct: 67 EAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDL------LRVNVSSVFYG 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
R A+ + + G +IN AS+A G+ AAYSASKA VV T LA D A
Sbjct: 121 CRAAIPHMRRQG------GGAIINVASIAGLRGETLAAAYSASKAAVVNFTRSLALDHAD 174
Query: 183 QGIRVVTIAPGLFRTPM---MEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN-- 237
+ IRV I PG T M M P+ + ++ ++P +R G P + A L + +
Sbjct: 175 ENIRVNAICPGSVETEMNNLMMSRPDYIAQWIK-TIP-ANRFGRPDDVAALAAFLASDDA 232
Query: 238 PMLNGETIRLDG--SLRM-QP 255
+ G+ I +DG S RM QP
Sbjct: 233 SFIVGQAIPVDGGTSARMAQP 253
>UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 258
Score = 111 bits (266), Expect = 2e-23
Identities = 75/261 (28%), Positives = 133/261 (50%), Gaps = 21/261 (8%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVIC----DLPSTKGQNTAKSLGENAVFAPV 57
F+ VALVTGGS G+G+A L ++G RV + + + ++LG + +
Sbjct: 12 FQNRVALVTGGSRGIGRACCLRLAQEGARVAVSYRSGKADAAETLRQIEALGGSGMIVQS 71
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+ E +V + + G ++ L+N +G + ++ + DL+ +Q + VNL
Sbjct: 72 DVSVETEVDRMVSEVEAQLGDIELLVNNSGT------FIYQSHEELDLSAWQQMLDVNLT 125
Query: 118 GTFNVI-RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
GTF V R+ G++ + Q G ++N +S++ + AY+ SKAGV+ T +
Sbjct: 126 GTFLVTWRVKPGMLKR-------QFGRIVNLSSLSGLQPRPKSIAYAVSKAGVISFTQSI 178
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII- 235
A A+ IRV IAPGL T ++ + + ++ + + P P R+G P+E A +V ++
Sbjct: 179 ATAWARDNIRVNAIAPGLIETEILSTVSQEDLEKIIEATPIP-RMGTPEEVAAIVSFLLS 237
Query: 236 -QNPMLNGETIRLDGSLRMQP 255
++ G+T+ L G M P
Sbjct: 238 EESNFTTGQTMVLSGGRCMLP 258
>UniRef50_A3Q4Y4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=7; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
JLS)
Length = 263
Score = 111 bits (266), Expect = 2e-23
Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 13/200 (6%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTS 61
F G LVTG +SG+G+AT + L+++G VV DLP A + + + D+
Sbjct: 4 FDGKGVLVTGAASGIGQATVQRLLEEGAYVVGLDLPE------ADRVADRYAYRRADILD 57
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
V +A+ + + GRLD +++ AGVA ++ E+ + + VNL GTF
Sbjct: 58 GQAVADAVAAVVAEAGRLDGVVHSAGVAGGGPIHLLPDEE------WDRVVDVNLKGTFV 111
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
V R A+ + + DG+RG ++N +S+ +G G ++Y+ASK GVV +T A D
Sbjct: 112 VNRAALTQMLQQ-DRVDGERGAIVNLSSIEGLEGTAGGSSYNASKGGVVLLTKNAAIDYG 170
Query: 182 KQGIRVVTIAPGLFRTPMME 201
GIRV I PG TP+ +
Sbjct: 171 PSGIRVNAICPGFIETPLFD 190
>UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL
DEHYDROGENASE; n=10; Proteobacteria|Rep:
TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL DEHYDROGENASE
- Brucella melitensis
Length = 262
Score = 110 bits (265), Expect = 3e-23
Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 14/253 (5%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VAL+TG SG G+ A+ K G +VVI D + A +G+ A+ D++ E
Sbjct: 14 EGKVALITGAGSGFGEGMAKRFAKGGAKVVIVDRDKAGAERVAGEIGDAALAVAADISKE 73
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
DV A++ L KFG++D L+N AG+ + N + +P + F + VN+ G + +
Sbjct: 74 ADVDAAVEAALSKFGKVDILVNNAGI--GHKPQNAELVEPEE---FDRIVGVNVRGVYLM 128
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
R + +N A GQ V++N AS A + A Y+A+K VV +T LA ++A
Sbjct: 129 TRKLIPHFKENG--AKGQECVILNVASTGAGRPRPNLAWYNATKGWVVSVTKALAIELAP 186
Query: 183 QGIRVVTIAPGLFRTPM----MEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--Q 236
IRVV + P TP+ M + E K S+P RL P + A + Q
Sbjct: 187 AKIRVVALNPVAGETPLLTTFMGEDSEEIRKKFRDSIPM-GRLLKPDDLAEAAAFLCSPQ 245
Query: 237 NPMLNGETIRLDG 249
M+ G + +DG
Sbjct: 246 ASMITGVALDVDG 258
>UniRef50_Q39FN1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=26; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Burkholderia sp. (strain 383) (Burkholderia
cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
Length = 258
Score = 110 bits (265), Expect = 3e-23
Identities = 78/206 (37%), Positives = 106/206 (51%), Gaps = 15/206 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAK---SLGENAVFAPVDV 59
+G VA+VTGG+ G+G+ A L G +++ DL TA+ +LG A A VDV
Sbjct: 6 EGQVAIVTGGARGIGRGIALTLAGAGADILLADLLDDALDATAREVRALGRRAAIAKVDV 65
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T V + L GRLD L+NCAGV S V E+ +D + VN GT
Sbjct: 66 TQAAQVDAMVAQALADLGRLDILVNCAGVISIHPVGELT-ERDWDF-----VMDVNAKGT 119
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F R A+ AP G +IN AS+A +G A YSASK VVG T LA++
Sbjct: 120 FLGCRAAL------APLKAQGHGRIINVASIAGKEGFPNLAHYSASKFAVVGFTNALAKE 173
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPE 205
+A+ G+ V I PG+ RT M ++L +
Sbjct: 174 LARDGVTVNAICPGIVRTYMWDRLSD 199
>UniRef50_Q1Q261 Cluster: Strongly similar to
3-oxoacyl-[acyl-carrier protein] reductase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to 3-oxoacyl-[acyl-carrier protein] reductase -
Candidatus Kuenenia stuttgartiensis
Length = 239
Score = 110 bits (265), Expect = 3e-23
Identities = 76/253 (30%), Positives = 132/253 (52%), Gaps = 25/253 (9%)
Query: 8 LVTGGSSGLGKATAELLVKQGGRVVI--C----DLPSTKGQNTAKSLGENAVFAPVDVTS 61
LVTGGS G+GKA ++ + +G V++ C D+ + + ++ G ++ DVT
Sbjct: 2 LVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEKLREEFSSPQ-GSFSI-EKADVTD 59
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+K+ + + K G++D LIN AG+ + + + + I VNL G FN
Sbjct: 60 YAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKD------WNDVINVNLTGVFN 113
Query: 122 VIR-LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+ ++ +IG+ + G +IN AS++ G GQ YSA+K GV+ T+ L++++
Sbjct: 114 CTKAVSEHMIGQRS-------GTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSKEL 166
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--P 238
A IRV T+APG+ T +++ L + S + +P R G P+E A +V+ + +
Sbjct: 167 APFCIRVNTVAPGVIETDIIDSLDKNKRNSYKEHIPL-KRFGKPEEVASVVRFLASSEAS 225
Query: 239 MLNGETIRLDGSL 251
+ GE IR+ G L
Sbjct: 226 YITGEVIRVSGGL 238
>UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent
epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1
Length = 263
Score = 110 bits (265), Expect = 3e-23
Identities = 80/259 (30%), Positives = 129/259 (49%), Gaps = 20/259 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQN---TAKSLGENAVFAPV 57
+ K VALVTG SSG+G ATA L +G +VV C KG+ ++ G A +
Sbjct: 3 ILKDKVALVTGASSGIGWATALTLAAEGAKVVACARREDKGRELIALIQAQGGQATWVTA 62
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV SE DV+ +Q L +GRLD N AG + + ++ + + N+
Sbjct: 63 DVLSERDVEAMVQAALTTYGRLDGAFNNAGTSLSKPFIEMTNDE------YDTVMATNVR 116
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
F ++ + + G G ++N ASV+A G +AYSASKAG+ +T +A
Sbjct: 117 SAFWCMKYQLKAM------LAGGGGAIVNCASVSAVRAMPGLSAYSASKAGLAALTRGVA 170
Query: 178 RDMAKQGIRVVTIAPGLFRTPMME---QLPEPAIKSLEASVPFPSRLGHPQEFALLVQSI 234
+ A++ IR T++PG+ + M +L + ++ +S +R+G PQE A LV +
Sbjct: 171 VEYAQKNIRANTVSPGIVESEMATAGWRLHDRMGRAFASSFQPMNRVGTPQEVAGLVAFL 230
Query: 235 IQN--PMLNGETIRLDGSL 251
+ + L G+ + +DG L
Sbjct: 231 LSDKASFLTGQDLAVDGGL 249
>UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:
Os07g0665000 protein - Oryza sativa subsp. japonica
(Rice)
Length = 310
Score = 110 bits (265), Expect = 3e-23
Identities = 68/197 (34%), Positives = 105/197 (53%), Gaps = 10/197 (5%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAV-FAPVDVTSE 62
G VA++TG +SG+G+ATA+ V+ G +V+I D+ G+ A LG +A + DVT E
Sbjct: 45 GKVAVITGAASGIGEATAKEFVRNGAKVIIADIQDDLGRAVAAELGADAASYTHCDVTVE 104
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
DV A+ + + + GRLD + + AGV A + DL+ + + VN
Sbjct: 105 KDVAAAVDLAVARHGRLDVVYSNAGVIGAPAPASLAA---LDLDEYDRVMAVNARSMLAC 161
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
++ A ++ A + G ++ TAS AA G + YS SKA +VGM +AR +A+
Sbjct: 162 VKHAARVM------APRRAGCILCTASSAAVLGGVASPVYSMSKAAIVGMVRAVARQLAR 215
Query: 183 QGIRVVTIAPGLFRTPM 199
G+RV I+P TPM
Sbjct: 216 DGVRVNAISPHAIPTPM 232
>UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Mycobacterium gilvum PYR-GCK|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium gilvum
PYR-GCK
Length = 260
Score = 110 bits (264), Expect = 4e-23
Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 13/250 (5%)
Query: 8 LVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDVKE 67
++TG +SG+G+A A+L++ +G RV+I DL + A +G NA+ +V + V
Sbjct: 12 VITGAASGIGRAAAQLMIGEGARVLIADLDADAAAAAASDIGGNAIGVAANVLDDKSVAA 71
Query: 68 ALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRLAV 127
+ + +FG +D L N G ++ + + + DL+ + + +N T RLA+
Sbjct: 72 MIDRAVTEFGGIDVLCNHVGGSNPHKDLDLLR---LDLDEWDRAMALNARSTVVASRLAL 128
Query: 128 GLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGIRV 187
+ A+G G +INT SVA G Q AY ASKA V+ +T +A ++G+R
Sbjct: 129 PHM-----IAEG-GGSIINTVSVAGLTGDTLQCAYGASKAAVIRLTQYIATQYGRKGVRC 182
Query: 188 VTIAPGLFRTP-MMEQLPEPAIKSLEASVPFPSRLGHPQE--FALLVQSIIQNPMLNGET 244
+APG TP + + +P I ++ + +G P++ +A++ + ++ + G+T
Sbjct: 183 NAVAPGAVMTPALADNVPAAVIDNIRSHNAL-DLIGSPEDIGWAMVYLASDESRYMTGQT 241
Query: 245 IRLDGSLRMQ 254
+ LDG L Q
Sbjct: 242 LVLDGGLTAQ 251
>UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine
gamma proteobacterium HTCC2080|Rep: Short chain
dehydrogenase - marine gamma proteobacterium HTCC2080
Length = 251
Score = 110 bits (264), Expect = 4e-23
Identities = 83/253 (32%), Positives = 121/253 (47%), Gaps = 18/253 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
KG VA+VTGG +G+G A A L + G V + D+ S A L G V DV
Sbjct: 6 KGKVAVVTGGGAGIGLACAARLAEAGVAVGVADIDSAAAHQAAADLTSQGHRCVAIVTDV 65
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+ +V++ QIT + FG ++ +N AGV + +E+ FD + VNL G
Sbjct: 66 SKAKEVEKLFQITNEAFGPINIAVNNAGVGAPLTPLGDTEEEDFD-----RVMAVNLKGV 120
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+ +R A+ + AP G +IN AS + G Y+ASK GV G+T A +
Sbjct: 121 WLCMRAALRHM---APQKSGS---IINMASALSTTTFPGSGLYTASKHGVAGLTRSAAVE 174
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQ-LPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ-- 236
+ GIR+ I PG TP++ + E A KS+ A P +RLG P E A V +
Sbjct: 175 YGESGIRINAICPGFISTPLLHSTVTEEAAKSMAARHPM-NRLGTPAEIADAVTYLASDA 233
Query: 237 NPMLNGETIRLDG 249
+ + G +DG
Sbjct: 234 SSFVTGSLFSIDG 246
>UniRef50_A1DKS5 Cluster: Short chain dehydrogenase/reductase family
oxidoreductase, putative; n=1; Neosartorya fischeri NRRL
181|Rep: Short chain dehydrogenase/reductase family
oxidoreductase, putative - Neosartorya fischeri (strain
ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 297
Score = 110 bits (264), Expect = 4e-23
Identities = 82/262 (31%), Positives = 128/262 (48%), Gaps = 23/262 (8%)
Query: 9 VTGGSSGLGKATAELLVKQGGRVVICDLP---STKG-----QNTAKSL----GENAVFAP 56
+TG SSG+G+A A L K+G V+ DL + +G + + L G ++F
Sbjct: 37 LTGASSGIGRAVALSLAKEGSHVICADLQPEANPRGFDARLETSTTDLILEGGRRSIFVR 96
Query: 57 VDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNL 116
VD++ V+ A + +FGRLD L+NCAG + R F +E D ++ + VN
Sbjct: 97 VDISDSKQVENAFSTVIKEFGRLDILVNCAGYWAPFR--QFAEE---DDELWSKMLAVNS 151
Query: 117 IGTFNVIRLAVGLIGKNAPDAD-GQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
GT + RLA+ K D G RG ++N +S A G+ AYS +KA V +T
Sbjct: 152 AGTGKMCRLAIRQFLKQGVDPSWGSRGRIVNISSAAGVIAFAGEVAYSITKASVNHLTRT 211
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQ--LPEPAIKSLEASVPFPSRLGHPQEF--ALLV 231
A D AK I V +APG T M E + ++ + P+P RLG+ Q+ A+L
Sbjct: 212 AALDHAKDSINVNCVAPGTVATGMARGNFEDEDILALMKRATPWP-RLGNTQDIAAAVLF 270
Query: 232 QSIIQNPMLNGETIRLDGSLRM 253
+ + G+ + +DG + +
Sbjct: 271 FCLPSSQWTTGQVLAVDGGMTL 292
>UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=4; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 268
Score = 110 bits (264), Expect = 4e-23
Identities = 84/254 (33%), Positives = 128/254 (50%), Gaps = 20/254 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL-GENAVFAP-VDVTS 61
G A+VTG + GLGK A L G V I D+ K + TA L GE V A VDVT
Sbjct: 22 GETAIVTGAAQGLGKQMATGLTDMGADVAIADVNVEKAERTASELDGETDVIATEVDVTD 81
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
E V+ ++ D+ G +D L+N AG+ V N E+ + ++ + VNL G F
Sbjct: 82 EGSVEAMVEDVTDRLGPIDVLVNNAGI-----VENSPAEET-SVESWRRVVSVNLDGVF- 134
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQ--AAYSASKAGVVGMTLPLARD 179
L +G+ + G ++N +S++ FD + Q A+Y+ +KAGV +T LA +
Sbjct: 135 ---LCAKHVGQQMLNRG--EGRIVNISSMSGFDVNVPQKQASYNTTKAGVRMLTQSLAVE 189
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPE--PAIKSLEASVPFPSRLGHPQEFALLVQSIIQ- 236
QG+RV IAPG RT +++++ E P ++ RLG P+E LV +
Sbjct: 190 WGDQGVRVNAIAPGYMRTELVDEVLEENPEMEETWLENTPMGRLGRPEELKELVVYLASD 249
Query: 237 -NPMLNGETIRLDG 249
+ + G T+ +DG
Sbjct: 250 ASSYMTGSTVVMDG 263
>UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=18;
Bacillales|Rep: Uncharacterized oxidoreductase yxbG -
Bacillus subtilis
Length = 273
Score = 110 bits (264), Expect = 4e-23
Identities = 81/258 (31%), Positives = 135/258 (52%), Gaps = 26/258 (10%)
Query: 7 ALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAP---VDVTSED 63
A++TG ++G+G+ATAE+ +G RV+I D+ + + T ++ +N A +DV+ E+
Sbjct: 9 AVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRKNGGQAESFHLDVSDEN 68
Query: 64 DVKEALQITLDKFGRLDALINCAGV-ASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
VK D G +D L N AGV +V+ E P DL F I V+L GTF
Sbjct: 69 SVKAFADQIKDACGTIDILFNNAGVDQEGGKVH----EYPVDL--FDRIIAVDLRGTFLC 122
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+ + L+ +N G +INT+S++ + ++ Y+A+K G+ +T +A D A+
Sbjct: 123 SKYLIPLMLENG-------GSIINTSSMSGRAADLDRSGYNAAKGGITNLTKAMAIDYAR 175
Query: 183 QGIRVVTIAPGLFRTPMMEQL-----PEPAIKSLEAS--VPFPSRLGHPQEFALLVQSII 235
GIRV +I+PG TP++++L E + EA+ + RLG P+E A + +
Sbjct: 176 NGIRVNSISPGTIETPLIDKLAGTKEQEMGEQFREANKWITPLGRLGQPKEMATVALFLA 235
Query: 236 --QNPMLNGETIRLDGSL 251
+ + GE I DG +
Sbjct: 236 SDDSSYVTGEDITADGGI 253
>UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;
n=11; cellular organisms|Rep: Uncharacterized
oxidoreductase TM_0019 - Thermotoga maritima
Length = 256
Score = 110 bits (264), Expect = 4e-23
Identities = 79/263 (30%), Positives = 131/263 (49%), Gaps = 21/263 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAV---FAPV 57
M +G VA+VTGG G+G A A+L + G +VVI ++ G + L E + F
Sbjct: 1 MLEGKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEAGVEREEMLRERGLDVTFVKT 60
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV E+ VK ++ T++ +G +D L+N A V S ++ E+P L ++ I+VNL
Sbjct: 61 DVADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIF----ERP--LEEWERVIRVNLT 114
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G + R + K GV+IN AS AF + YSASK G+V +T LA
Sbjct: 115 GPYICSRYCAEEMIKRGG------GVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA 168
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQ---LPEPAIKSLEASVPFPSRLGHPQEFALLVQSI 234
+++ IRVV+I+PG T ++ +P ++ ++ R+G+P + A L +
Sbjct: 169 VSLSRYHIRVVSISPGWIETSEWKKKSLRKKPDLRPIDHEQHPAGRVGNPLDIAHLCVFL 228
Query: 235 IQNP---MLNGETIRLDGSLRMQ 254
+ + G +DG + ++
Sbjct: 229 ADDEKAGFITGTNFIVDGGMTVK 251
>UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein)
reductase; n=3; Bacteria|Rep:
3-ketoacyl-(Acyl-carrier-protein) reductase -
Psychromonas sp. CNPT3
Length = 244
Score = 109 bits (263), Expect = 5e-23
Identities = 81/254 (31%), Positives = 123/254 (48%), Gaps = 17/254 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNT-AKSLGENAVFAPVDVTS 61
K V LVTG S G+G+A AE V G V+ S KG ++ LG++ ++VT
Sbjct: 4 KDQVVLVTGASRGIGRAIAEKFVSLGA-TVLGTATSEKGATAISEYLGDSGKGFVLNVTD 62
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
D + + + +D L+N AG+ + + K ++ D+ I NL F
Sbjct: 63 NDSIAALFAVIKKDYIGVDILVNNAGITRDNLLMRMKDDEWNDI------IDTNLTPIFK 116
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ + + P + G +IN SV G GQA Y+A+KAGV+G T LAR++A
Sbjct: 117 MSKAVM------RPMMKKRAGRIINIGSVVGTMGNAGQANYAAAKAGVIGFTKSLAREIA 170
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PM 239
+GI V T+APG T M + L + + A+VP RLG E A V + +
Sbjct: 171 SRGITVNTVAPGFIETDMTKALTDEQREKTLANVP-AGRLGFASEIAATVAFLASDGAAY 229
Query: 240 LNGETIRLDGSLRM 253
+ GETI ++G + M
Sbjct: 230 ITGETIHVNGGMYM 243
>UniRef50_Q12DF3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=38; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 250
Score = 109 bits (263), Expect = 5e-23
Identities = 68/215 (31%), Positives = 116/215 (53%), Gaps = 17/215 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTK---GQNTAKSLGENAVFAPVDVTSE 62
VA++TGG+ G+G ATA+ ++ G V + D+ + + + T K G+ + A V++T E
Sbjct: 10 VAVITGGAQGMGYATAQRMLASGAAVALWDIDAQRLAQARETLKPSGK-VITAVVELTDE 68
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASAS-RVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
V+ A Q TL FGR+D L+N AG+ + + E +++ I+VNLIG +
Sbjct: 69 ASVEAATQATLAAFGRIDILVNNAGITGGNGTTWELAPE------VWRRVIEVNLIGPYL 122
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
R V + K G ++N ASVA +G + YSASKAG++G+T L +++A
Sbjct: 123 TSRAIVPHMVKQG------YGRIVNIASVAGKEGNPNASHYSASKAGLIGLTKSLGKELA 176
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVP 216
K G+ V + P +T + + + + I + + +P
Sbjct: 177 KTGVLVNAVTPAAAKTAIFDSMKQEHIDFMLSKIP 211
>UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain
dehydrogenase/reductase SDR - Xanthobacter sp. (strain
Py2)
Length = 255
Score = 109 bits (263), Expect = 5e-23
Identities = 86/260 (33%), Positives = 125/260 (48%), Gaps = 22/260 (8%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFA---PVDVT 60
G VALVTG +SG+G A A+LL +QG VV+ D + A++LG + A DVT
Sbjct: 9 GKVALVTGAASGIGLAAAQLLARQGAHVVLADRDGAAAEAAAQALGAAGMRASSQAFDVT 68
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
E V E + L GR+D L+N AG++ + + L+ ++ VN+ G F
Sbjct: 69 DEAAVGEGVAQVLAALGRVDILVNNAGLSIRKGIADLA------LSDWEKVFAVNVTGAF 122
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFD--GQIGQAAYSASKAGVVGMTLPLAR 178
R V A A G G ++N AS+ G AY ASK +V +T LA
Sbjct: 123 LTTRAVV-----PAMRAQG-AGAIVNIASIMGLSGGGPYPNPAYQASKGAIVNLTRGLAV 176
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPA--IKSLEASVPFPSRLGHPQEF--ALLVQSI 234
++A GIRV +AP RTP + L A + +EA +P R+ P+E A+L +
Sbjct: 177 ELAPAGIRVNAVAPTWVRTPFIAPLMNDAEQLARIEALMPM-GRIAEPEEVADAVLFLAS 235
Query: 235 IQNPMLNGETIRLDGSLRMQ 254
M+ G + +DG Q
Sbjct: 236 PMASMITGHILPVDGGFLCQ 255
>UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4;
Legionella pneumophila|Rep: Acetyoacetyl CoA reductase -
Legionella pneumophila (strain Corby)
Length = 248
Score = 109 bits (263), Expect = 5e-23
Identities = 80/260 (30%), Positives = 132/260 (50%), Gaps = 20/260 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPS-TKGQ---NTAKSLG-ENAVFA 55
M V L+TGG+ +G A A+ L V+ DL S +G+ + K+ G +N F
Sbjct: 1 MLNNNVVLITGGTGDIGTAVAKQLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFR 60
Query: 56 PVDVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVN 115
+DVT + E + + +++FG +D LIN AG+ + K Q + ++VN
Sbjct: 61 HMDVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQ------WDEVLRVN 114
Query: 116 LIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
L G FNV + V + + G ++N +SV A GQ QA Y+ASKAGV G T
Sbjct: 115 LDGMFNVTKQVVESMKVQ------ESGRIVNVSSVNAQKGQFSQANYAASKAGVYGFTKS 168
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
LA+++ + I V +I+PG T +M+ + ++ + +P RL PQE A ++ +I
Sbjct: 169 LAQELMIKNITVNSISPGYVNTRLMKGIRPDILEGIINLIP-AKRLAEPQEIAWAIEFLI 227
Query: 236 --QNPMLNGETIRLDGSLRM 253
++ + G + ++G L M
Sbjct: 228 SEKSRYITGANLSVNGGLHM 247
>UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Nocardioides sp. (strain BAA-499 / JS614)
Length = 246
Score = 109 bits (263), Expect = 5e-23
Identities = 75/251 (29%), Positives = 120/251 (47%), Gaps = 16/251 (6%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
+A+VTG G+GKA A L +G VV+ D+ + TA +L A+ DVT V
Sbjct: 8 IAVVTGAGQGIGKAIATKLAAEGATVVVTDVDHQAAKETAAALDHGAIGLHADVTDRTSV 67
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ + FGR+D L+N AG F +P + I +NL G N +
Sbjct: 68 DAMVDEVVATFGRIDVLVNNAGWDKGEA---FVDSEP---ETWDRIIGINLYGVLNTSKK 121
Query: 126 AVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGI 185
+ ++ A G G V+N S A G G+A YSA+K GV+ + AR+MA+ +
Sbjct: 122 VLPIMA-----AQGS-GSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAREMARSQV 175
Query: 186 RVVTIAPGLFRTPMMEQLPEPAIK-SLEASVPFPSRLGHPQEFALLVQSIIQNP--MLNG 242
V + PG T + + ++ +L ++PF RLG P++ A +V + + + G
Sbjct: 176 NVNCVCPGPTDTALFASMGGDKLREALVKAIPF-RRLGQPEDLANVVAFLASDEAGFVTG 234
Query: 243 ETIRLDGSLRM 253
+T+ + G L M
Sbjct: 235 QTVSVSGGLTM 245
>UniRef50_Q9LW35 Cluster: Alcohol dehydrogenase-like protein; n=6;
rosids|Rep: Alcohol dehydrogenase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 300
Score = 109 bits (263), Expect = 5e-23
Identities = 62/197 (31%), Positives = 108/197 (54%), Gaps = 9/197 (4%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VA++TGG+SG+GKATAE V QG +V+I D+ G A LG A F DVT E
Sbjct: 37 EGKVAVITGGASGIGKATAEEFVSQGAQVIIVDIDEEAGHMVATELGSAAHFLRCDVTEE 96
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ + +A++ + + G+LD ++N AG++ + + D++ + +++N+ GT
Sbjct: 97 EQIAKAVETAVTRHGKLDVMLNSAGISCSISPPSI---ADLDMDTYDKVMRLNVRGTVLG 153
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
I+ A + P G ++ +S++ G +G AYS SK + G+ +A ++ K
Sbjct: 154 IKHAARAM---IPAGSGS---ILCLSSISGLMGGLGPHAYSISKFTIPGVVKTVASELCK 207
Query: 183 QGIRVVTIAPGLFRTPM 199
G+R+ I+P TP+
Sbjct: 208 HGLRINCISPAGIPTPL 224
>UniRef50_Q76KV8 Cluster: Short-chain alcohol dehydrogenase A; n=9;
core eudicotyledons|Rep: Short-chain alcohol
dehydrogenase A - Pisum sativum (Garden pea)
Length = 277
Score = 109 bits (263), Expect = 5e-23
Identities = 76/213 (35%), Positives = 115/213 (53%), Gaps = 15/213 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGR-VVICDLPSTKGQNTAKSLG-ENAVFAPVDVTS 61
G VA+VTGG+SG+GK TA L Q R VVI D+ G A+S+G + F D+
Sbjct: 24 GKVAIVTGGASGIGKETAHLFANQAARMVVIADIQDELGIQVAESIGTDRCTFIHCDIRI 83
Query: 62 EDDVKEALQITLDKFGRLDALINC-AGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
EDDVK +Q T+D +G++D +I+C AG+ S S + D++ N IGT
Sbjct: 84 EDDVKNLVQSTVDTYGQID-IIHCNAGIISPSDQTLLE----LDVSQANGVFATNAIGTA 138
Query: 121 NVIRLAVGLIGKNAPDADGQ-RGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
++ A + DG+ RG ++ TAS++A G YS SK V+G+ +
Sbjct: 139 LCVKHAARAM------VDGKVRGSIVCTASISASYGVTTGTDYSMSKHAVLGLMRSASVQ 192
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLE 212
+AK GIRV +++P TP+ E+L + K++E
Sbjct: 193 LAKYGIRVNSVSPNGLATPLTEKLLDADAKTVE 225
>UniRef50_P14697 Cluster: Acetoacetyl-CoA reductase; n=25;
Bacteria|Rep: Acetoacetyl-CoA reductase - Ralstonia
eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 246
Score = 109 bits (263), Expect = 5e-23
Identities = 81/254 (31%), Positives = 126/254 (49%), Gaps = 19/254 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPST----KGQNTAKSLGENAVFAPVDVTS 61
+A VTGG G+G A + L K G RVV P++ K K+LG + + + +V
Sbjct: 5 IAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVAD 64
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
D K A + G +D LIN AG+ +R F+K D + I NL FN
Sbjct: 65 WDSTKTAFDKVKSEVGEVDVLINNAGI---TRDVVFRKMTRAD---WDAVIDTNLTSLFN 118
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
V + + + AD G ++N +SV GQ GQ YS +KAG+ G T+ LA+++A
Sbjct: 119 VTKQVIDGM------ADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVA 172
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQ--SIIQNPM 239
+G+ V T++PG T M++ + + + + A++P RLG P+E A + S ++
Sbjct: 173 TKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPV-KRLGLPEEIASICAWLSSEESGF 231
Query: 240 LNGETIRLDGSLRM 253
G L+G L M
Sbjct: 232 STGADFSLNGGLHM 245
>UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces
avermitilis|Rep: Putative dehydrogenase - Streptomyces
avermitilis
Length = 258
Score = 109 bits (262), Expect = 7e-23
Identities = 83/259 (32%), Positives = 128/259 (49%), Gaps = 28/259 (10%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G V L++G + G G+ A L V++G +VV+ D+ +G+ AK +G A + +DV ED
Sbjct: 6 GRVVLISGAARGQGEQEARLFVEEGAKVVVADVLDDQGEALAKEIG--ARYVHLDVGRED 63
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
D + A+ + D +G +D L+N AG+ +N P L FQ +QVN +G F
Sbjct: 64 DWQAAVTVAKDAYGHIDGLVNNAGILR----FNDLVGTP--LAEFQQIVQVNQVGVF--- 114
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
L + + A G G ++NTAS A G AY+A+K +VG+T A ++A +
Sbjct: 115 -LGIKTVAPEIEAAGG--GTIVNTASYAGLTGMAYVGAYTATKHAIVGLTRVAALELAAK 171
Query: 184 GIRVVTIAPGLFRTPMM--EQL-----PEPAIKSLE----ASVPFPSRLGHPQEFALLVQ 232
IRV + PG T M QL PE ++L VP R+G P+E A L
Sbjct: 172 KIRVNAVCPGAIDTAMSNPSQLDPGADPEETARALSELYGRLVPL-GRIGRPEEVARLAL 230
Query: 233 SII--QNPMLNGETIRLDG 249
+ + + G+ +DG
Sbjct: 231 FLSGEDSSYITGQPFVIDG 249
>UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=3; Cyanobacteria|Rep: NAD-dependent
epimerase/dehydratase precursor - Anabaena variabilis
(strain ATCC 29413 / PCC 7937)
Length = 251
Score = 109 bits (262), Expect = 7e-23
Identities = 85/262 (32%), Positives = 124/262 (47%), Gaps = 20/262 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
M K VALVTGG+SG+G+ATA KQ +VV+ +G+ T + + G A F
Sbjct: 2 MLKDKVALVTGGTSGIGRATAIAYAKQQAKVVVVGRRIDEGEETVRLIQEAGGEAFFVQS 61
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DVT E DVK + + FGRLD N AG+ + + E +D + VN+
Sbjct: 62 DVTKEADVKAMVDKAVGVFGRLDIAFNNAGMVGENPSLIEQTEAEYD-----RIMNVNVK 116
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G + ++ + + K G ++NT+S A G Y+ASK VVG+T A
Sbjct: 117 GVWLSMKYEIAQMLKQGS------GAIVNTSSGAGVVALPGVPLYTASKHAVVGLTKAAA 170
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLP--EPAIKSLEASVPFPSRLGHPQEFA---LLVQ 232
AK GIR+ +APG T M E + +K+ + R+G P E A L +
Sbjct: 171 LQYAKAGIRINAVAPGSIETDMFEAATGGQDEVKAYITGLHPIGRIGTPLEVANAVLFLS 230
Query: 233 SIIQNPMLNGETIRLDGSLRMQ 254
S I + + GE + +DG Q
Sbjct: 231 SDIAS-FITGEMLMVDGGFVAQ 251
>UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 306
Score = 109 bits (262), Expect = 7e-23
Identities = 69/190 (36%), Positives = 103/190 (54%), Gaps = 12/190 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VA++TG SG+G++ A L ++G RVV D+ S + TAK++G+ A+ VDVTS +
Sbjct: 66 GKVAVITGAGSGIGRSAAFLFAREGARVVCADV-SGREALTAKAVGDGAIAVHVDVTSTE 124
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
D++ + +D+FG+LD L N AG E FD + VN+ G + +
Sbjct: 125 DIERMITTAVDRFGKLDVLYNNAGFTGPIVPLAEAGEDYFDA-----VMAVNVKGVYLGM 179
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ A+ ++ G G +INTAS A G G A Y+A+K VV +T A D A +
Sbjct: 180 KAAIPVM------LAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAALDYAAK 233
Query: 184 GIRVVTIAPG 193
GIRV + PG
Sbjct: 234 GIRVNAVCPG 243
>UniRef50_Q2CHI2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Oceanicola granulosus HTCC2516|Rep: Short-chain
dehydrogenase/reductase SDR - Oceanicola granulosus
HTCC2516
Length = 261
Score = 109 bits (262), Expect = 7e-23
Identities = 78/251 (31%), Positives = 121/251 (48%), Gaps = 20/251 (7%)
Query: 8 LVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDVKE 67
LVTG ++G+G+A A++L +G R+V+ D + + TA LG V VT D
Sbjct: 11 LVTGAANGIGQAVAQVLAAEGARLVLLDRDAAALEETAAGLGGEVVTQAGSVTEARDCDA 70
Query: 68 ALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRLAV 127
A+ L++FG LD + + AG+ V + ++ I VNL G F V + A+
Sbjct: 71 AVAAALERFGGLDGVSHNAGIQRYGDVVETSRA------LWDEVIDVNLTGAFVVSKAAM 124
Query: 128 GLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQGIRV 187
P RG ++ T SV +F Q G AY A+K G+ G+ +A D A G+RV
Sbjct: 125 -------PALRQARGALVLTGSVQSFAAQQGALAYVAAKHGLAGLVAGMAVDEAAHGVRV 177
Query: 188 VTIAPGLFRTPMMEQL----PEPAIKSLEASVPFP-SRLGHPQEFALLVQSII--QNPML 240
+APG TPM+ P+PA + P R +E A ++ ++ Q +
Sbjct: 178 NGVAPGSVDTPMLRASIALDPDPAALNRVIDGMHPLGRRARAEEVAEVIAFLLGGQASFV 237
Query: 241 NGETIRLDGSL 251
GE +R+DG +
Sbjct: 238 TGEMVRVDGGM 248
>UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1;
Bifidobacterium adolescentis L2-32|Rep: Putative
uncharacterized protein - Bifidobacterium adolescentis
L2-32
Length = 330
Score = 109 bits (262), Expect = 7e-23
Identities = 79/255 (30%), Positives = 128/255 (50%), Gaps = 20/255 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE--NAVFAPVDV 59
+ G ALVTG G+G+A A+LL +G +V + D+ + +NT K + + FA +
Sbjct: 84 WNGQRALVTGAGQGIGRAVAQLLASKGVKVAVNDIVPERAENTVKLIADAGGEAFAAIGD 143
Query: 60 TSEDDVKEALQITLD-KFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
++ V E L LD +FG +D L+N AG+ + DL + + VNL
Sbjct: 144 IADPTVVEDLFRQLDERFGGIDILVNVAGIIIKDSL------DDTDLERWNRILAVNLTA 197
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDG--QIGQAAYSASKAGVVGMTLPL 176
F I+ AV + K G ++N +S+AA G +G AY+++KAGV +T
Sbjct: 198 DFLTIKQAVKRMRKQ------HYGRIVNVSSIAAKHGGGYLGGVAYASTKAGVAALTRGA 251
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII- 235
AR+ A GI V + PGL TPM +P+ +++E S G P + A + +
Sbjct: 252 AREYAPDGINVNAVMPGLTYTPMTAGMPDWKREAIEDST-LVKHGGQPYDIARAIAFLAD 310
Query: 236 -QNPMLNGETIRLDG 249
++ ++GET+ +DG
Sbjct: 311 PESGYIDGETLDVDG 325
>UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=3; Planctomycetaceae|Rep:
3-oxoacyl-(Acyl-carrier protein) reductase -
Blastopirellula marina DSM 3645
Length = 256
Score = 109 bits (262), Expect = 7e-23
Identities = 76/253 (30%), Positives = 127/253 (50%), Gaps = 18/253 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVDVT 60
GL A+VTG S G+GK+ A + +G +V + + K +T ++ G A DVT
Sbjct: 15 GLTAIVTGASQGIGKSIATAMASRGAKVAVVARNAEKLADTVAIIEAAGGVAQAYSCDVT 74
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+ V+ + ++K+ +LD L+N AGV + + ++ + N I+ NL G F
Sbjct: 75 KRESVEAVVDAVMEKWEKLDVLVNNAGVTRDNLLPVMTDDE------WDNVIETNLRGMF 128
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
R A K A + G +IN +SV+ G GQ YSASKAG++G T L+R++
Sbjct: 129 LFTRAA----SKQMMRA--RFGRIINISSVSGLMGNPGQTNYSASKAGMIGFTRSLSREL 182
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA--LLVQSIIQNP 238
K+ + V I PG + M + L + ++ +P R+G P+E A +L + Q
Sbjct: 183 GKRKVTVNAICPGFIESDMTKALGPAVMDEVKKRIP-AQRMGKPEEIADGVLFLASPQAA 241
Query: 239 MLNGETIRLDGSL 251
+ G+ + +DG +
Sbjct: 242 YITGQVLTIDGGM 254
>UniRef50_Q14RS1 Cluster: ABA4 protein; n=4; Pezizomycotina|Rep:
ABA4 protein - Botrytis cinerea (Noble rot fungus)
(Botryotinia fuckeliana)
Length = 258
Score = 109 bits (262), Expect = 7e-23
Identities = 80/262 (30%), Positives = 131/262 (50%), Gaps = 21/262 (8%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNT-AKSLGE---NAVFAPV 57
F V +TG +SG+G TA+LL +G R+ + D+ K + A E + + V
Sbjct: 6 FTNKVIALTGSASGIGLETAKLLASRGARLSLADIQEDKLKELQAXXESEYHVDVITTKV 65
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV +V+ + T+D FG+LD N AGVA S EQ DL+ ++ + VNL
Sbjct: 66 DVRKFGEVEAWINKTIDNFGKLDGSANLAGVAPESIGLKGIVEQ--DLDEWEFVLGVNLT 123
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
GT N ++ + ++ N G ++N +S+ G A+YS++K G++G+T A
Sbjct: 124 GTMNSLKAQLKVMANN--------GSIVNASSIRGLTGAAKNASYSSAKHGIIGLTRTAA 175
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLE-ASVPFP----SRLGHPQEFALLVQ 232
+++ +GIRV I PG TPM++ L+ S +P R G +E A LV
Sbjct: 176 KEVGGKGIRVNAICPGRISTPMLKTAENSIGLHLQPGSANYPPIALGRDGEAKEVAQLVA 235
Query: 233 SII--QNPMLNGETIRLDGSLR 252
++ ++ ++G I +DG R
Sbjct: 236 FLLSDESTYISGADISIDGGWR 257
>UniRef50_Q8ZVW5 Cluster: Short chain dehydrogenase family; n=3;
Pyrobaculum|Rep: Short chain dehydrogenase family -
Pyrobaculum aerophilum
Length = 243
Score = 109 bits (262), Expect = 7e-23
Identities = 77/251 (30%), Positives = 133/251 (52%), Gaps = 21/251 (8%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNT----AKSLGENAVFAPVDVTS 61
VA+VTGGS+G+G A + L K+G V L S + A+S G ++ D TS
Sbjct: 3 VAVVTGGSTGIGAAVVKTLAKRGYDVAFTYLKSERVAEAVAKEAESHGVRILYRRADATS 62
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
++++ FG++DAL+ AG R N + DL+ ++ I +NL +
Sbjct: 63 WEEMRAFADEVRRVFGKVDALVANAGGLPQRR--NLDES---DLDYWKTLIDLNLTSAYI 117
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQ-IGQAAYSASKAGVVGMTLPLARDM 180
+L V ++ ++GVV+ +S+AA+ G G AY+A+KAG++G+T LA+++
Sbjct: 118 ATKLFVPMM---------EKGVVVYVSSIAAYTGGGRGAFAYAAAKAGLLGLTRALAKEL 168
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--P 238
+GIRVV + PGL TP E+ I + ++ + R+G P+E A ++ ++ +
Sbjct: 169 GPRGIRVVAVLPGLINTPFHEKAQTGDIDAWARNMVYMRRVGKPEEVAEVIAFLVSDGAS 228
Query: 239 MLNGETIRLDG 249
+NG I ++G
Sbjct: 229 YINGAFIDVNG 239
>UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Thermotoga|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Thermotoga maritima
Length = 257
Score = 109 bits (261), Expect = 9e-23
Identities = 76/214 (35%), Positives = 113/214 (52%), Gaps = 20/214 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
K VALVTGG G+GKA A+ L G V+I D+ + T + + G A F DV
Sbjct: 11 KRKVALVTGGGQGIGKAIAQALAAAGAAVLIMDINEETARRTVEEIKEKGGEADFYVGDV 70
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T E+D A++ LD++G+LD +N AG+ N+ E+ ++ I VNL+G
Sbjct: 71 TKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEK------WKKVIDVNLVGV 124
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAF--DGQIGQAAYSASKAGVVGMTLPLA 177
F + + + + G +IN AS++ + Q AY+ASKAGV+ +T LA
Sbjct: 125 FLSAKAEFHAMKER------KYGKIINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA 178
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSL 211
+ A GIRV +I+PG RTP++E P +K L
Sbjct: 179 AEWAPYGIRVNSISPGYIRTPLIE---SPNVKDL 209
>UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Rep:
Blr3449 protein - Bradyrhizobium japonicum
Length = 256
Score = 109 bits (261), Expect = 9e-23
Identities = 80/256 (31%), Positives = 122/256 (47%), Gaps = 20/256 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
+ K + +VTG G+G+A A G RVV+ DL + + A+ + G+ A+ +
Sbjct: 10 LLKDRLVVVTGAGQGIGRAIALGAAAAGARVVVTDLGQDRADSVAREIRDGGKEAIGCSL 69
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DVT E + ++ G D ++N AG+ + + P ++ VN+
Sbjct: 70 DVTDALACGEVARRVDEELGLADVVVNNAGIIIREPI-----DSPRAHENWRQVFDVNVN 124
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
GTFNV+ + + K+ G +IN ASVAAF G YS+SK V T LA
Sbjct: 125 GTFNVVHAFIPALRKSP-------GTIINVASVAAFGSMGGTVGYSSSKGAVRLFTQALA 177
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQL-PEPA-IKSLEASVPFPSRLGHPQEFA--LLVQS 233
RD+A GIRV +APG+ T M E PA + L A P R+G P+E A ++ +
Sbjct: 178 RDLAPDGIRVNAVAPGIIATEMSESTRGNPARLSGLMARTPL-KRVGQPEEIAAPVIFLA 236
Query: 234 IIQNPMLNGETIRLDG 249
+NG + +DG
Sbjct: 237 SAMASYVNGVILPVDG 252
>UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Short chain dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 275
Score = 109 bits (261), Expect = 9e-23
Identities = 82/265 (30%), Positives = 132/265 (49%), Gaps = 29/265 (10%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VA+VTG +SG+G ATA ++G RVV+ D+ +GQ A LG+ + DV +E
Sbjct: 6 GKVAVVTGAASGIGAATARAFAERGARVVVADIDDPRGQAVAAGLGDRGAYLHTDVRNEA 65
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFD--LNIFQNTIQVNLIGTFN 121
DV+ A+ + +D+FGRLD ++N AG A + F ++ D N F + +GT +
Sbjct: 66 DVEAAVAVAVDRFGRLDCMVNNAGRVGA---WTFLEDTSLDEWENGFAMLARSAFLGTKH 122
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
R+ G G G ++N +SVA G YSA+KA V+ +T A ++A
Sbjct: 123 AARVMRG---------QGS-GSIVNVSSVAGIRTGFGPHPYSAAKAAVLQLTRTAAVELA 172
Query: 182 KQGIRVVTIAPGLFRTPMMEQ---LPEPAI--------KSLEASVPFPSRLGHPQEFALL 230
+ IRV + PG T ++ L + A+ +SL P P R G P++ A
Sbjct: 173 EYRIRVNALIPGGVATRIVGHGAGLEDDALDRSVDAVRRSLTNFQPIP-RAGEPEDLAHA 231
Query: 231 VQSII--QNPMLNGETIRLDGSLRM 253
+ + + G+++ +DG L +
Sbjct: 232 AAYLASDDSTFVTGQSLGVDGGLTL 256
>UniRef50_A4XEN1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Novosphingobium aromaticivorans DSM 12444|Rep:
Short-chain dehydrogenase/reductase SDR -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 253
Score = 109 bits (261), Expect = 9e-23
Identities = 80/201 (39%), Positives = 104/201 (51%), Gaps = 15/201 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VALVTGG+SGLG A +L ++G RVVI D+ GQ A + N VF DV E
Sbjct: 11 GKVALVTGGASGLGAEDARVLAREGARVVITDMQEDLGQKVASEI-PNCVFLKQDVRDEA 69
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
E + TL FGRLD L+N AG+ V ++ +D Q + GTF
Sbjct: 70 RWGEVVAETLRLFGRLDTLVNNAGLVRFGTV----EDLSWDDYKLQTDVMAG--GTFLGC 123
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ A+ + K DG G +IN ASV G AY+A+KAG++GMT +A +Q
Sbjct: 124 KAAIPHMSK-----DGS-GSIINMASVGGIKGISAIPAYAAAKAGIIGMTRSIAVHCREQ 177
Query: 184 G--IRVVTIAPGLFRTPMMEQ 202
G IR +IAPG TPM Q
Sbjct: 178 GYRIRCNSIAPGGIVTPMTAQ 198
>UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular
organisms|Rep: Os07g0664000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 572
Score = 109 bits (261), Expect = 9e-23
Identities = 71/202 (35%), Positives = 102/202 (50%), Gaps = 10/202 (4%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VA++TGG+SG+GKATA +K G +V+I D+ G + A LG +A + DV E
Sbjct: 313 GKVAVITGGASGIGKATATEFIKNGAKVIIADIQDDLGHSVAAELGPDAAYTRCDVADEA 372
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
V A+ + + + GRLD N AG+A A + DL F + VN T +
Sbjct: 373 QVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDM---AAVDLGDFDRVMAVNARSTLAAV 429
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ A + AP G V+ T+S A YS SKA V+ + A MA+
Sbjct: 430 KHAARAM---APRCS---GCVLCTSSGAGVIPVPAVPVYSVSKATVIAIVRAAAEPMARH 483
Query: 184 GIRVVTIAPGLFRTP-MMEQLP 204
G+RV I+PG RTP ++ Q+P
Sbjct: 484 GLRVNAISPGATRTPLLLRQIP 505
>UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2;
Euryarchaeota|Rep: Predicted short chain dehydrogenase -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 253
Score = 109 bits (261), Expect = 9e-23
Identities = 72/257 (28%), Positives = 126/257 (49%), Gaps = 21/257 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPV---DV 59
KG VA++TG ++G+GK+ A L ++G ++ + + + N A DV
Sbjct: 4 KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERLEQITNEINSNGGDASACIGDV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T ++D+ +++ LDK+G++D ++N AG+ +F + D +++ TI VNL G
Sbjct: 64 TKQEDIDNVVKLALDKYGKIDIIVNNAGIMD-----DFVSVKHIDDDLWDKTIDVNLTGP 118
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+IR + + KN G +I +SV G+I AAY+ASK GV+G+ A
Sbjct: 119 MRLIRAVIPEMIKN------NGGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV 172
Query: 180 MAKQGIRVVTIAPGLFRTPMME-----QLPEPAIKSLEASVPFPSRLGHPQEFALLVQSI 234
K IR IAPG T + ++ ++++ V +LG +E A + +
Sbjct: 173 YGKHNIRSNVIAPGTVNTEIATTINPGRMDMETYETIDPFVKLSPKLGQSKEIAQIALFL 232
Query: 235 I--QNPMLNGETIRLDG 249
+ +NG+ I+ DG
Sbjct: 233 ASDDSSFVNGDVIKADG 249
>UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=26; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 248
Score = 109 bits (261), Expect = 9e-23
Identities = 76/253 (30%), Positives = 122/253 (48%), Gaps = 18/253 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVT 60
G +VTGGS G+G +L ++ G V I L +GQ +SL G FA VDV+
Sbjct: 7 GKKVIVTGGSRGIGLGIVKLFLENGADVEIWGLNEERGQAVIESLTGLGGEVSFARVDVS 66
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
VK+ +Q LDK ++D L+N AG+ + + ++ +Q+ I NL +
Sbjct: 67 HNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDD------WQSVISTNLTSLY 120
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+ + K + G +IN AS+ A G GQ Y+A+KAG++ T LA+++
Sbjct: 121 YTCSSVIRHMIK------ARSGSIINVASIVAKIGSAGQTNYAAAKAGIIAFTKSLAKEV 174
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ--NP 238
A + IRV +APG T M L + S+P R G P++ A + + +
Sbjct: 175 AARNIRVNCLAPGFIETDMTSVLNDNLKAEWLKSIPL-GRAGTPEDVARVALFLASQLSS 233
Query: 239 MLNGETIRLDGSL 251
+ +T+ +DG L
Sbjct: 234 YMTAQTLVVDGGL 246
>UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3;
Bordetella|Rep: Putative oxidoreductase - Bordetella
parapertussis
Length = 262
Score = 108 bits (260), Expect = 1e-22
Identities = 81/252 (32%), Positives = 124/252 (49%), Gaps = 16/252 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDL-PSTKGQNTAKSLGEN--AVFAPVDVT 60
G VAL+TG + G+G A A +G + + D P Q + G+ A+ DVT
Sbjct: 16 GRVALITGAAGGIGSAAALRFAAEGAALALLDRRPDAIEQLAGRICGQGGQAIGVAADVT 75
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
+D V++A++ ++ FGR+D L NCAG + A K DL ++ T++++L T
Sbjct: 76 DDDSVRQAVRRAVEHFGRIDTLFNCAGGSVAGDTAVDK----VDLALWNRTLRLDLDSTM 131
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
R AV I + A G G V+N +S A G G AY+A+K V+ +T LA +
Sbjct: 132 LCCRHAVPAIVR----AGG--GAVVNMSSGAGLRGSFGGHAYTAAKGAVIALTRALAAEY 185
Query: 181 AKQGIRVVTIAPGLFRTP-MMEQLPEPAIKSLEASVPFPSRLGHPQEFA--LLVQSIIQN 237
A G+RV I G RT ++ L A A+ +P R G P + A L + ++
Sbjct: 186 APHGVRVNAICAGRIRTERILRNLDAGAPAQAGAAQRYPCREGDPIDIAHIALFLASHES 245
Query: 238 PMLNGETIRLDG 249
M+ GE I +G
Sbjct: 246 RMITGEAIAANG 257
>UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein;
n=2; Streptomyces|Rep: Ketoacyl ACP/CoA reductase-like
protein - Streptomyces natalensis
Length = 257
Score = 108 bits (260), Expect = 1e-22
Identities = 75/257 (29%), Positives = 128/257 (49%), Gaps = 19/257 (7%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
+ G V+L+TG SSG+G ATA L ++G VV+ + + + G A +
Sbjct: 7 LLSGKVSLITGASSGIGAATARLFAREGAAVVLAARRVDRLRALVSEIRRTGAEAAYIAT 66
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+ E+DV+ A++ T++K+GRLD N AGV + ++ +D + + N+
Sbjct: 67 DVSQEEDVRRAVEFTVEKYGRLDLAFNNAGVGCDHESMHLMQQDTYD-----DVMGTNVR 121
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
G ++ ++ + + N G G ++N +SVA A Y ASK V+G+T A
Sbjct: 122 GVWHCLQHEISAMLHN-----GVGGSIVNNSSVAGLQAIPAGAPYIASKHAVIGLTKAAA 176
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQL--PEPAI-KSLEASVPFPSRLGHPQEFALLVQSI 234
+ A QGIRV ++APG RT ++ P + + L + P +R P+E A V +
Sbjct: 177 AEYAPQGIRVNSVAPGTTRTEIIAGWFDRNPGLEEQLHRATP-QARTAEPEEIAQAVAWL 235
Query: 235 I--QNPMLNGETIRLDG 249
++ + G + +DG
Sbjct: 236 CSDRSSFVTGAVLPVDG 252
>UniRef50_Q2IT70 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Rhodopseudomonas palustris (strain HaA2)
Length = 254
Score = 108 bits (260), Expect = 1e-22
Identities = 86/259 (33%), Positives = 127/259 (49%), Gaps = 20/259 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
+G VALVTGG +GLG+ A L G RV + D+ Q A L G+ A+ +DV
Sbjct: 9 EGRVALVTGGGNGLGEIIAGALHGAGYRVAVADIDEAAAQTVATRLDPGGQTAIALHLDV 68
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+ D + AL L ++G L+N A V A V E+ F I VNL GT
Sbjct: 69 RLKGDFEAALAALLARWGGAHVLVNNAAVTVARPVMEISPEE------FDAVIAVNLRGT 122
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAA-YSASKAGVVGMTLPLAR 178
F L + G DA G ++N AS+A +G A Y+ASK G+V +T AR
Sbjct: 123 F----LGCQVFGAYFRDAG--HGRIVNMASLAGQNGGTATGAHYAASKGGIVTLTKVFAR 176
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQ-LPEPAIKSLEASVPFPSRLGHPQEFALLVQSII-- 235
D+ K G+ V IAPG P++ + +P +A++P +G P+ A LV +
Sbjct: 177 DLGKAGVTVNAIAPGPLDLPIVHKTVPAERFAEFKANIPV-GDIGDPKFVAQLVLQLASP 235
Query: 236 QNPMLNGETIRLDGSLRMQ 254
++ ++G T ++G L M+
Sbjct: 236 ESGFVSGATWDVNGGLFMR 254
>UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Roseovarius sp. HTCC2601
Length = 255
Score = 108 bits (260), Expect = 1e-22
Identities = 79/257 (30%), Positives = 123/257 (47%), Gaps = 21/257 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLG---ENAVFAPVDV 59
+G +VTG SG+G AT L++ G VV DL Q T LG AV VDV
Sbjct: 5 EGRTYIVTGAGSGIGAATVARLIEDGANVVAVDLDQAAAQKTLDGLGLDASRAVAVGVDV 64
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+ ED V + KFG LD ++NCAGV + + D ++ + VN+ G+
Sbjct: 65 SDEDKVDAMTAEGIAKFGGLDGVVNCAGVRGVGNILDT------DHGVWDLNMNVNIEGS 118
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
FN + ++ + G ++N +S A + + +Y SK GVVG+T +A +
Sbjct: 119 FNTSQAFCRYAREH-----NRPGSIVNISSQAGVEAVPNRLSYVTSKHGVVGLTRGVAIE 173
Query: 180 MAKQGIRVVTIAPGLFRTPM---MEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
MA GIR IAPG+ T M M PE ++ + + P R G P+E A ++ ++
Sbjct: 174 MAPHGIRCNGIAPGMIATAMTAGMRADPE-NLEKIRKAHPI-GREGQPEEIAAVISFLLS 231
Query: 237 N--PMLNGETIRLDGSL 251
+ + G + +DG +
Sbjct: 232 DDASYVTGIMMPVDGGI 248
>UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Burkholderia ambifaria AMMD|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia cepacia
(strain ATCC 53795 / AMMD)
Length = 252
Score = 108 bits (260), Expect = 1e-22
Identities = 82/253 (32%), Positives = 121/253 (47%), Gaps = 18/253 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVTSE 62
VALVTG +SG+GKATA L ++G +V I +G+ + + G A+F DV
Sbjct: 8 VALVTGATSGIGKATAMLFAREGAKVAIAARREEEGRQVVREILDHGGEAIFVRTDVAQA 67
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+D A+ T+ FG+LD N AG+ S R EQ + I VNL GTF
Sbjct: 68 EDCAAAVARTVASFGKLDIAFNNAGITSFGRPVADTDEQ-----AWSTVIDVNLTGTFLS 122
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQ-IGQAAYSASKAGVVGMTLPLARDMA 181
++ + I K A G G +IN +S G G +Y ASK GV+G+T A + A
Sbjct: 123 MKYEIPEILK----AGG--GSIINMSSAYGLAGSAFGACSYHASKHGVIGLTRAAALEYA 176
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFP-SRLGHPQEFALLVQSIIQ--NP 238
K+ +RV I P T M+ E ++ + + P R+G E A V + +
Sbjct: 177 KEKLRVNAICPAFVATDMIGAFLEQPEQAAQLAALHPVGRMGTLAETAEAVVFLASDAST 236
Query: 239 MLNGETIRLDGSL 251
+ G T+ +DG +
Sbjct: 237 FITGTTLSIDGGM 249
>UniRef50_A4M0F5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Geobacter bemidjiensis Bem
Length = 237
Score = 108 bits (260), Expect = 1e-22
Identities = 79/250 (31%), Positives = 121/250 (48%), Gaps = 27/250 (10%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTS 61
F G A+VTGG+ GLG A L+ G RV + D+ +G E+ F VD+T
Sbjct: 7 FNGRTAVVTGGARGLGLAITRALLSHGARVHVFDVAPGEG-------AEDYQFHKVDITD 59
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
V A+ + + L+N AG+ V+ ++ + + + VNL G FN
Sbjct: 60 PASVAAAVAAIPEP---VTLLVNNAGITRDRSVFKMSDDE------WSSVLGVNLTGAFN 110
Query: 122 VIR-LAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+ R LA G+ D G ++N S+ G+ GQA YSASKAG++G+T LAR++
Sbjct: 111 MARALAPGM-------RDAGYGRIVNITSINGIRGKFGQANYSASKAGLIGLTKTLAREL 163
Query: 181 AKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP-- 238
+G+ V +APG+ T M LPE + P L P++ A V ++ +
Sbjct: 164 GPKGVTVNAVAPGMVLTDMALALPEEILDRARNECLLP-ELAKPEDIANAVTFLLSDAAG 222
Query: 239 MLNGETIRLD 248
+ GE IR+D
Sbjct: 223 KITGEVIRVD 232
>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Bacillus coagulans 36D1|Rep: Short-chain
dehydrogenase/reductase SDR - Bacillus coagulans 36D1
Length = 262
Score = 108 bits (260), Expect = 1e-22
Identities = 83/265 (31%), Positives = 125/265 (47%), Gaps = 30/265 (11%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN---AVFAPVD 58
F G VA+VTGG G+G+ L G VV+ DL G+ TA + EN A+F D
Sbjct: 6 FTGKVAIVTGGGGGIGREACLKLAAGGANVVVADLSDELGEETAGKIRENGGEAIFVRTD 65
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ DV+ ++ LD +G++D L+N AG + E+ FD + +N+ G
Sbjct: 66 VSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFD-----KLMGINVRG 120
Query: 119 TFNVIRLAVGLIGKNAPDADGQR-GVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
F ++ + P Q+ G ++NTASVA G AY ASK V+GMT
Sbjct: 121 VFLGMKYVL-------PHMISQKSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG 173
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQL-----------PEPAIKSLEASVPFPSRLGHPQE 226
+ A G+RV + PG+ T MM ++ E + + AS P R P+E
Sbjct: 174 IEAAPSGVRVNAVCPGVVDTEMMRKIENGFAGGDSAAAEQTRQQMAASAP-TGRYTQPEE 232
Query: 227 FA--LLVQSIIQNPMLNGETIRLDG 249
A LL + + + G+T+ +DG
Sbjct: 233 VANVLLYLASDLSSHIIGQTVVIDG 257
>UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1;
marine gamma proteobacterium HTCC2143|Rep: Short-chain
dehydrogenase/reductase - marine gamma proteobacterium
HTCC2143
Length = 264
Score = 108 bits (260), Expect = 1e-22
Identities = 68/197 (34%), Positives = 103/197 (52%), Gaps = 12/197 (6%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VA++TGG+SG+G+ATA++ +K+G VV+ KGQ A LG+ A + DV+ E
Sbjct: 6 QGKVAIITGGTSGIGEATADIYIKEGATVVLTGRSEEKGQAIANRLGDKAHYIKADVSKE 65
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+D+ + T+++FG+LD L N AG + + P D+N + + L
Sbjct: 66 EDIANTISETVERFGKLDVLFNNAGGPVGGTIDSI---APGDINY---GVDLLLSSVVLG 119
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
IR A+ + N GV+IN S+AA + G YSA KA V T ++
Sbjct: 120 IRYAIEPMKANG------GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAGVELGP 173
Query: 183 QGIRVVTIAPGLFRTPM 199
GIRV I+PG TP+
Sbjct: 174 LGIRVNCISPGAIATPI 190
>UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=9; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex
aeolicus
Length = 248
Score = 108 bits (260), Expect = 1e-22
Identities = 74/255 (29%), Positives = 129/255 (50%), Gaps = 19/255 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL----GENAVFAPVD 58
+G V+LVTG + G+G+A AE L G V+I + + A+ + G A ++
Sbjct: 6 QGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMN 65
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
+ SE+ + +A + + +D L+N AG+ +R F + D ++ ++VNL G
Sbjct: 66 LLSEESINKAFEEIYNLVDGIDILVNNAGI---TRDKLFLRMSLLD---WEEVLKVNLTG 119
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
TF V + ++ + K + G ++N +SV F G +GQ YS +KAG++G T LA+
Sbjct: 120 TFLVTQNSLRKMIKQ------RWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAK 173
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN- 237
++A + + V +APG T M L E + + +P R G P+E A +V +
Sbjct: 174 ELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPL-GRFGSPEEVANVVLFLCSEL 232
Query: 238 -PMLNGETIRLDGSL 251
+ GE I ++G +
Sbjct: 233 ASYITGEVIHVNGGM 247
>UniRef50_Q930L3 Cluster: Putative; n=2; Sinorhizobium|Rep: Putative
- Rhizobium meliloti (Sinorhizobium meliloti)
Length = 257
Score = 108 bits (259), Expect = 2e-22
Identities = 84/258 (32%), Positives = 122/258 (47%), Gaps = 18/258 (6%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN---AVFAPV 57
+F V VTG SG+G+A A L + G V + D + TA+ + A +
Sbjct: 4 LFSNKVVTVTGAGSGIGRAIALGLARDGATVHLADRDADGLTQTAELIRAEDGRAFTTEL 63
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV SE V ++ GRLDA N AG+ + K+ + + L FQ I VNL
Sbjct: 64 DVASELQVVGWIEQIGSTSGRLDAAFNNAGITGPA-----KRIEDYPLEDFQRVIAVNLQ 118
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
F ++ + LI +N G ++NTAS+AA G G +AY+ASK GV G+T +A
Sbjct: 119 SVFLGMKYQIPLIKRNGG------GSIVNTASIAALTGPGGMSAYAASKHGVQGLTRVVA 172
Query: 178 RDMAKQGIRVVTIAPGLFRTPMM--EQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
+ A GIRV IAPG TPM+ PA +L + R G P+E A +
Sbjct: 173 MENAAHGIRVNAIAPGWTETPMVAANSQQNPAFAALAQNAIPAKRGGKPEEIAAAAIWLA 232
Query: 236 QN--PMLNGETIRLDGSL 251
+ + G + +DG +
Sbjct: 233 SDAASYVTGHMLTVDGGM 250
>UniRef50_Q1NAA1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Sphingomonas sp. SKA58|Rep: Short-chain
dehydrogenase/reductase SDR - Sphingomonas sp. SKA58
Length = 248
Score = 108 bits (259), Expect = 2e-22
Identities = 83/250 (33%), Positives = 124/250 (49%), Gaps = 19/250 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G V LVTG + GLG+A AE L ++G RV++ D+ + Q A L A+ +DVTSE
Sbjct: 8 EGKVVLVTGAAHGLGRADAEALAREGARVIVADVDEEEAQRVADGL-PAAIALRLDVTSE 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ AL + GRLDAL+N AG+A+ F+ + L +F+ + V+ GTF
Sbjct: 67 AQWQAALTKIMWAHGRLDALVNNAGIAA------FETVEQSSLEVFRRVMAVSAEGTFLG 120
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
R + + A G G ++N ASVAA G AYSA+K ++ MT L +
Sbjct: 121 CRTCLPALA-----ASG-AGSIVNIASVAAIRGNPSVFAYSAAKGAILSMTRSLIVHCQQ 174
Query: 183 QG--IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNP 238
QG +R + PG T M+ + A L + G P+ A LV ++ ++
Sbjct: 175 QGYPVRANVVLPGSHDTQMVRDAYQFAAPELREAA--QRHEGQPEHVADLVLFLVSDESA 232
Query: 239 MLNGETIRLD 248
LNG I +D
Sbjct: 233 RLNGAEIVID 242
>UniRef50_A6F000 Cluster: Putative short-chain
dehydrogenase/reductase; n=1; Marinobacter algicola
DG893|Rep: Putative short-chain dehydrogenase/reductase
- Marinobacter algicola DG893
Length = 255
Score = 108 bits (259), Expect = 2e-22
Identities = 82/255 (32%), Positives = 129/255 (50%), Gaps = 18/255 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
KG VA+VTGG G+G+A A L ++G VVI ++ + A+ L G A+ DV
Sbjct: 6 KGRVAIVTGGGHGIGRAYARRLAEEGASVVIAEIDVKAATSAAEELEKEGFEALAVHTDV 65
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T D VKE ++ +KFGR+D L+N A + + + ++ D + + VN+ G
Sbjct: 66 TKPDSVKEMARLAAEKFGRIDILVNNAAIFISVPMSRAPFDE-IDPEEWDRMMAVNVKGA 124
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+ + AV + D Q G +IN +S A G + Y ASKA ++G T LA +
Sbjct: 125 W-LSSCAVAPYMR-----DQQYGKIINISSGTALKGADNRIHYVASKAAILGFTKTLANE 178
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFP---SRLGHPQEF--ALLVQSI 234
+ K+G+ V IAPG + M E+ P+ AI+ AS RL P + A++ S
Sbjct: 179 LGKEGVCVNCIAPG---STMSEENPDDAIRQRRASAASTRAIPRLQMPGDMLGAVVFFSS 235
Query: 235 IQNPMLNGETIRLDG 249
+ + G+T+ +DG
Sbjct: 236 SDSDFITGQTLVVDG 250
>UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Nocardioides sp. JS614|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 258
Score = 108 bits (259), Expect = 2e-22
Identities = 88/265 (33%), Positives = 125/265 (47%), Gaps = 24/265 (9%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVD 58
F VA++TG SG+G+A AELL +G V + DL + + T ++ G A+ +
Sbjct: 6 FDNKVAVITGAGSGIGRAAAELLASEGAAVGVLDLRAESAEETVAAIVDSGGRAIALAAN 65
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V +V+ A+ + ++G L+ L N AG S V + E ++ VN G
Sbjct: 66 VADSAEVEAAIAKVVAEYGGLNVLYNNAGCDSRGSVADATDED------WERAFSVNAKG 119
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
TF R AV + A G G ++N SVAA G AAY A+K VV +T +A
Sbjct: 120 TFVCSRAAVPHL-----TASGG-GAIVNQGSVAALVGVPNFAAYCAAKGAVVALTRSMAI 173
Query: 179 DMAKQGIRVVTIAPGLFRTPMME-QLPEPAIKSLEAS-----VPFP-SRLGHPQEFALLV 231
D+A + IRV I PG TP+ME L LEA V +P RLG P+E A +
Sbjct: 174 DLAPRKIRVNVICPGTVFTPLMEPMLRARGDGDLEAGLAKTLVKYPIGRLGTPEEIARVA 233
Query: 232 QSII--QNPMLNGETIRLDGSLRMQ 254
+ + L G I DG + Q
Sbjct: 234 AFLASDDSSFLTGSVIAADGGMTAQ 258
>UniRef50_Q2UNR9 Cluster: Dehydrogenases with different
specificities; n=6; Pezizomycotina|Rep: Dehydrogenases
with different specificities - Aspergillus oryzae
Length = 253
Score = 108 bits (259), Expect = 2e-22
Identities = 81/259 (31%), Positives = 131/259 (50%), Gaps = 22/259 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICD-----LPSTKGQNTAKSLGENAVFAPV 57
+G V VTGG+SG+G ATA+L+ ++GG V I D L + + +AKS + V
Sbjct: 4 QGKVYAVTGGASGIGFATAKLISERGGTVCIADVNADCLGNVESYFSAKSPSVEFMITQV 63
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV+++ V+ + K+ RLD N AGV + K + + + I VNL
Sbjct: 64 DVSNKQQVENWIADIKTKYHRLDGAANIAGVIGKD--HGIKTVAELEDDEWNKIISVNLT 121
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
GT +R + I DG G ++N AS+ A G AY+ASK GV+G+T A
Sbjct: 122 GTMYCLRAELNHI------VDG--GSIVNMASIHATTGVANHGAYAASKHGVLGLTRVAA 173
Query: 178 RDMAKQGIRVVTIAPGLFRTPMM----EQLPEPAIKSLEASVPFPSRLGHPQEFALLVQS 233
++ + +RV +APG TPMM +++ P+ + + F R G P+E A +V
Sbjct: 174 KENGHREVRVNAVAPGPIYTPMMQGFYDRIERPSDAPFDDPIAF-KRQGTPEEVAKVVVF 232
Query: 234 II--QNPMLNGETIRLDGS 250
++ ++ ++G +DG+
Sbjct: 233 LLGPESSFVSGSCYPVDGA 251
>UniRef50_Q9LBG2 Cluster: Levodione reductase (EC 1.1.1.-)
((6R)-2,2,6-trimethyl-1,4- cyclohexanedione reductase);
n=4; Bacteria|Rep: Levodione reductase (EC 1.1.1.-)
((6R)-2,2,6-trimethyl-1,4- cyclohexanedione reductase) -
Leifsonia aquatica (Corynebacterium aquaticum)
Length = 267
Score = 108 bits (259), Expect = 2e-22
Identities = 84/262 (32%), Positives = 129/262 (49%), Gaps = 25/262 (9%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPV---- 57
F V L+TGG SGLG+ATA L +G ++ + D+ S + + ++ E A A V
Sbjct: 11 FTDRVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTV 70
Query: 58 -DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNL 116
DV+ E V+ + T ++FGR+D N AG+ + F F + +NL
Sbjct: 71 ADVSDEAQVEAYVTATTERFGRIDGFFNNAGIEGKQN-----PTESFTAAEFDKVVSINL 125
Query: 117 IGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
G F + + ++ + G+V+NTASV G Q+ Y+A+K GVVG+T
Sbjct: 126 RGVFLGLEKVLKIMREQGS------GMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNS 179
Query: 177 ARDMAKQGIRVVTIAPGLFRTPM----MEQL-PEPAIKSLEASVPF-PS-RLGHPQEFAL 229
A + + GIR+ IAPG TPM M+QL PE K+ E + PS R G E A
Sbjct: 180 AVEYGRYGIRINAIAPGAIWTPMVENSMKQLDPENPRKAAEEFIQVNPSKRYGEAPEIAA 239
Query: 230 LVQSIIQN--PMLNGETIRLDG 249
+V ++ + +N + +DG
Sbjct: 240 VVAFLLSDDASYVNATVVPIDG 261
>UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Bacteria|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Pseudomonas putida (strain KT2440)
Length = 262
Score = 107 bits (258), Expect = 2e-22
Identities = 79/255 (30%), Positives = 119/255 (46%), Gaps = 17/255 (6%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTA---KSLGENAVFAPVD 58
F G V LVTG SG+G+ATA + G V + D+ + G T K+ G A F VD
Sbjct: 7 FSGKVVLVTGAGSGIGRATALAFAQSGASVAVADISTDHGLKTVELVKAEGGEATFFHVD 66
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V SE V+ L + +G LD N AG+ + N D + ++ I VNL
Sbjct: 67 VGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEA-----NIVPLAELDSDNWRRVIDVNLSS 121
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
F ++ + L+ K G ++NTAS + G + Y+A+K GVVG+T A
Sbjct: 122 VFYCLKGEIPLMLKRGG------GAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAAI 175
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN- 237
D A Q IR+ + PG +P + +P+P L P RL +E A V + +
Sbjct: 176 DYANQNIRINAVCPGPVDSPFLADMPQPMRDRLLFGTPI-GRLATAEEIARSVLWLCSDD 234
Query: 238 -PMLNGETIRLDGSL 251
+ G ++ +DG +
Sbjct: 235 AKYVVGHSMSVDGGV 249
>UniRef50_A4E921 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 249
Score = 107 bits (258), Expect = 2e-22
Identities = 80/254 (31%), Positives = 122/254 (48%), Gaps = 17/254 (6%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTS 61
F G A+VTGG+ G+G A+ +V GG V + + KG+ LGE F +DV
Sbjct: 5 FTGKTAIVTGGTQGIGLEIAKGIVAGGGHVALIARNAAKGEAAVAELGEGNKFYQLDVAD 64
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+E ++ + + LINCAGV S KK D ++ TI +NL GTF
Sbjct: 65 APKARETVEQIFTDLPQTNILINCAGVIST------KKFDEIDDTEWRRTIDINLNGTFT 118
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAA--FDGQIGQAAYSASKAGVVGMTLPLARD 179
++ AV K A G ++N +SVA G +G AAY++SKAGV G+T +A++
Sbjct: 119 MMN-AVYPHFKAA-----HAGTIVNVSSVAGKIGGGLLGTAAYASSKAGVNGLTKAVAKE 172
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPF--PSRLGHPQEFALLVQSIIQN 237
K G+R + P L T M L + + + +P ++ P + L S + +
Sbjct: 173 GGKFGVRCNAVCPSLTLTDMTSILSDENSQRIINGIPLGRAAQASEPAQMVLFFASDLAS 232
Query: 238 PMLNGETIRLDGSL 251
+NGE DG +
Sbjct: 233 -FVNGEIGDCDGGI 245
>UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6;
Bacteroidetes|Rep: Acetoin(Diacetyl)reductase -
Croceibacter atlanticus HTCC2559
Length = 254
Score = 107 bits (258), Expect = 2e-22
Identities = 83/256 (32%), Positives = 126/256 (49%), Gaps = 21/256 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDV 59
KG VA+VTG + G+G A+ L + G VV+ + G + L G A + DV
Sbjct: 5 KGKVAVVTGATGGIGFEVAKRLGQDGYTVVLNGIDHETGAKRVEELTAEGMTAEYYGFDV 64
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAG-VASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
T E+DV ++ +K+GR+D L+N AG + SR E ++N + +NL
Sbjct: 65 TKEEDVTSNIKAIGEKYGRIDVLVNNAGGLGGRSRFEEMTTE------FYRNVMALNLDS 118
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFD-GQIGQAAYSASKAGVVGMTLPLA 177
F R A+ + KN G+ +IN S A + G G Y SKAGV +T LA
Sbjct: 119 VFFASRAAIPFL-KN-----GEHPSIINYTSNAGWTAGGPGAGIYGTSKAGVHAITRALA 172
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPE--PAIKSLEASVPFPSRLGHPQEFALLVQSII 235
+D+A+ GIRV ++PG TP Q+ E P + + A+ RLG P++ A +V +
Sbjct: 173 KDLAEYGIRVNAVSPGTIDTPFHAQIKETKPEVFASWANNIMLGRLGQPEDVASVVSFLA 232
Query: 236 QN--PMLNGETIRLDG 249
+ ETI++ G
Sbjct: 233 SKDASFITAETIQIGG 248
>UniRef50_A2QZI1 Cluster: Contig An12c0160, complete genome; n=1;
Aspergillus niger|Rep: Contig An12c0160, complete genome
- Aspergillus niger
Length = 265
Score = 107 bits (258), Expect = 2e-22
Identities = 80/261 (30%), Positives = 127/261 (48%), Gaps = 16/261 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAP-VDVTSE 62
G +VTGG SG+G A L+ + V + D+ ST Q + +N F P DVTS
Sbjct: 10 GKAYVVTGGCSGIGLAILHYLLARSAIVHVLDISSTPPQVPSHLPHKNLHFYPNTDVTSG 69
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
V+ + LIN AG+A V + ++ FD + VN+ G +NV
Sbjct: 70 SIVRNVFTQIRTITPTIHGLINNAGIAYQPVVTGLESDELFD-----RVMDVNVRGVWNV 124
Query: 123 IRLAVG-LIGKNAPD------ADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
+ ++ + A + A RGV++N S+A+F G +G +Y+ SK V+GMT
Sbjct: 125 GNAYLSHILSREADEQPNPAAAKEGRGVIVNLCSIASFRGNLGYVSYTVSKHAVLGMTRA 184
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAI-KSLEASVPFPSRLGHPQEFALLVQSI 234
A + A QG+RV +APG TP+++ + E + E+ VP R P+E A V +
Sbjct: 185 WATNFAAQGVRVNGVAPGGTDTPLLQGIMEKDFQEQYESQVPLGKRCARPEEIADAVGFL 244
Query: 235 I--QNPMLNGETIRLDGSLRM 253
+ ++ + G+ I +DG M
Sbjct: 245 LGKESSYMTGQVITVDGGRYM 265
>UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase,
putative glucose-1-dehydrogenase; n=1; Pyrococcus
abyssi|Rep: Short-chain alcohol dehydrogenase, putative
glucose-1-dehydrogenase - Pyrococcus abyssi
Length = 240
Score = 107 bits (258), Expect = 2e-22
Identities = 79/255 (30%), Positives = 128/255 (50%), Gaps = 23/255 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVIC----DLPSTKGQNTAKSLGENAVFAPVD 58
KG VAL+TG S G+G+A A L K+G VVI + + K + + G + D
Sbjct: 4 KGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTEELCRQYGVETLLVKAD 63
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V++ ++V+E ++ +DKFGR+D LIN AG+ ++ ++ +D I VNL G
Sbjct: 64 VSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWD-----RVISVNLKG 118
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
F V + + + ++G ++N AS+A DG Y+ASK G++ +T LAR
Sbjct: 119 AFIVTQEVLRYM---------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR 169
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNP 238
+A I V +APG T M+ + +K L + + P E A V +++N
Sbjct: 170 HLA-PNILVNAVAPGPVDTDMLSSEMKEMLKKLSLT----GDIAKPSEVAHAVIFLLEND 224
Query: 239 MLNGETIRLDGSLRM 253
+ GE I ++G M
Sbjct: 225 HITGEVIDVNGGRLM 239
>UniRef50_Q97UA4 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=5; Archaea|Rep: 3-oxoacyl-(Acyl carrier
protein) reductase - Sulfolobus solfataricus
Length = 252
Score = 107 bits (258), Expect = 2e-22
Identities = 85/257 (33%), Positives = 131/257 (50%), Gaps = 24/257 (9%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE--NAVFAP--VDV 59
G +A+VTGG+SG+G+A A L G VV+ D+ + +N + + ++ P V+V
Sbjct: 9 GRIAIVTGGASGIGRAIAFKLASLGATVVLGDVKLEELKNVVNEITQQTSSKVLPLYVNV 68
Query: 60 TSEDDVKEALQITLDKFG--RLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
+ KE Q + G +D L+N AG+ + EQ + ++V+L
Sbjct: 69 GDFNSAKEFYQKATEILGIDYVDILVNNAGINRDALFVKMTFEQ------WDEVMKVDLY 122
Query: 118 GTFNVIRLAV-GLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
FN+ + V G+I +N G +IN +S++ G IGQA YSA+KAGV+G T L
Sbjct: 123 SMFNMTKQVVDGMIRRNY-------GRIINMSSMSWL-GNIGQANYSAAKAGVIGFTKTL 174
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQ--SI 234
AR++AK I V I PG TPM +PE + + +P R+G P+E A L+ S
Sbjct: 175 ARELAKYNITVNAITPGFIDTPMTRAVPEKVRQKIIERIPM-GRVGSPEEVANLIAFLSS 233
Query: 235 IQNPMLNGETIRLDGSL 251
+ + GE I + G L
Sbjct: 234 EEASYITGEVIGVTGGL 250
>UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=1;
Natronomonas pharaonis DSM 2160|Rep: Probable
dehydrogenase/ reductase 4 - Natronomonas pharaonis
(strain DSM 2160 / ATCC 35678)
Length = 253
Score = 107 bits (258), Expect = 2e-22
Identities = 77/259 (29%), Positives = 126/259 (48%), Gaps = 24/259 (9%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVD 58
F+ +TG SG+G+ATA + ++G VV D+ G+ T ++ G +A F +D
Sbjct: 3 FENDTVFITGAGSGIGRATALKVAREGAFVVATDINEDGGRETVDAVEDAGGDAAFHELD 62
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
VT D+ K ++ D++G LDA+IN AGV E F+ + VNL G
Sbjct: 63 VTDADEFKAVVETAADEYG-LDAMINNAGVGHPPAYTEDVTETTFEY-----VLDVNLRG 116
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
+N + A+ + + G+ G ++N S+A+F G QA YS +K V+ +T +A
Sbjct: 117 VWNGCQAALPHL-----KSQGE-GAIVNVGSLASFLGLPKQAVYSLTKGAVLNLTRAIAS 170
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQL------PEPAIKSLEASVPFPSRLGHPQEFALLVQ 232
+ + G+R + PG TP+ +Q PE A E P RLG P+E A +
Sbjct: 171 EAGRDGVRANAVCPGFIETPLGDQFFQSKRDPEKAKAETEKQYPL-GRLGEPEEVADAIA 229
Query: 233 SIIQN--PMLNGETIRLDG 249
+ + ++G + +DG
Sbjct: 230 FLASDEASFVSGHGLVVDG 248
>UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid
dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or
20-beta)-hydroxysteroid dehydrogenase - Mycobacterium
bovis
Length = 260
Score = 107 bits (258), Expect = 2e-22
Identities = 66/202 (32%), Positives = 103/202 (50%), Gaps = 12/202 (5%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G VALV+GG+ G+G + +V +G +VV D+ +G+ A L + A + +DVT
Sbjct: 7 GKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAVAAELADAARYVHLDVTQPA 66
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
A+ + FG L L+N AG+ + + + + L +Q + VNL G F I
Sbjct: 67 QWTAAVDTAVTAFGGLHVLVNNAGILNIGTI------EDYALTEWQRILDVNLTGVFLGI 120
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
R V P + RG +IN +S+ G + Y+A+K V G+T A ++
Sbjct: 121 RAVV------KPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPS 174
Query: 184 GIRVVTIAPGLFRTPMMEQLPE 205
GIRV +I PGL +TPM + +PE
Sbjct: 175 GIRVNSIHPGLVKTPMTDWVPE 196
>UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier
protein) reductase - Oceanobacillus iheyensis
Length = 253
Score = 107 bits (257), Expect = 3e-22
Identities = 75/255 (29%), Positives = 119/255 (46%), Gaps = 19/255 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN---AVFAPVDV 59
K VA+VTG +SG+GKA A L +G +V++ DL Q+ + + N A V++
Sbjct: 4 KDKVAIVTGAASGMGKAIATLYASEGAKVIVADLNEEGAQSVVEEITSNNGVATAIKVNI 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
++D+ + + +D +G LD L+N AG+ ++ +DL IF +N G
Sbjct: 64 AQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDL-IFD----INTKGV 118
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+R A+ + + + GV++NTAS +G AAY ASK V+G+T
Sbjct: 119 MRAMRKAIPIF------LEKESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTGYM 172
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLP---EPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
A GIR IAPG T + L E +A R+G P+E A + +
Sbjct: 173 YANSGIRCNAIAPGGVATNITSSLKGFNEFGFGRTKAVQGVMPRVGQPEEIAQVALFLAS 232
Query: 237 N--PMLNGETIRLDG 249
+ +NG + DG
Sbjct: 233 DDASFVNGTVVTADG 247
>UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Staphylococcus
epidermidis|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 255
Score = 107 bits (257), Expect = 3e-22
Identities = 76/254 (29%), Positives = 126/254 (49%), Gaps = 23/254 (9%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL----GENAVFAPVDV 59
G VA+V GG++G+GKA AE L + G +VI DL S GQ TA ++ G +D+
Sbjct: 12 GKVAMVIGGATGIGKAMAEALAQAGANIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T D+V + + + ++G++D L+N A ++ N E+ + I ++L G
Sbjct: 72 THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEE------WLKEINLSLNGA 125
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAF--DGQIGQAAYSASKAGVVGMTLPLA 177
F+V + +G+ + G +IN +SV + Q++Y SKAGV +T LA
Sbjct: 126 FSVAQ----TVGRQMIEKGS--GSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLA 179
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ- 236
R+ ++ GI+V IAPG RT E++ + E + R+G P+E A + +
Sbjct: 180 REWSRYGIKVNAIAPGYMRTIETEKILN---DNTETNTTPMERVGEPEELAGITVYLASD 236
Query: 237 -NPMLNGETIRLDG 249
+ G +DG
Sbjct: 237 ASSFTQGSVFNIDG 250
>UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Burkholderiaceae|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 252
Score = 107 bits (257), Expect = 3e-22
Identities = 78/251 (31%), Positives = 127/251 (50%), Gaps = 18/251 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
VALVTG +SG+G+A A LL +G RVV+ D+ G+ A+ +G+ A+F D+ E
Sbjct: 8 VALVTGAASGVGRADALLLAAEGARVVLTDIDEDAGRALAREIGDAALFVRHDIADEAGW 67
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ A+ TLD+FGRLD L+N A + + + L+ ++ ++ N G F +
Sbjct: 68 QHAIASTLDRFGRLDVLVNNAAICPVGSI------EDTSLDTWRRVMRTNADGYFLGCKY 121
Query: 126 AVGLI-GKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
A+G + G + P G ++ +SVAA G AY+ SK V + +A + G
Sbjct: 122 AIGAMKGNDTP------GSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVAVHCKRSG 175
Query: 185 --IRVVTIAPGLFRTPMMEQL-PEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QNPM 239
IR +I P TPM + L P+ +L +R+ PQ+ A LV + ++
Sbjct: 176 YRIRCNSIHPDGIWTPMTQALMPDLDPAALGIGSDPMARMCDPQDVANLVLFLASDESRF 235
Query: 240 LNGETIRLDGS 250
+NG +R+D +
Sbjct: 236 VNGAELRIDNA 246
>UniRef50_Q2W431 Cluster: Dehydrogenase with different
specificities; n=2; Magnetospirillum|Rep: Dehydrogenase
with different specificities - Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264)
Length = 248
Score = 107 bits (257), Expect = 3e-22
Identities = 78/260 (30%), Positives = 126/260 (48%), Gaps = 24/260 (9%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVD 58
F+ VAL+TGG+SG+G T + + + G V+I D+ G+ A L G A F +D
Sbjct: 3 FEDKVALITGGASGIGYCTVKSMAELGADVLIADINVEAGEKAAAELTAKGFKAEFVRLD 62
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPF---DLNIFQNTIQVN 115
VT + ++ + + GRLD L N AG QPF D + +N
Sbjct: 63 VTDKANIARVKEHVVATRGRLDILCNVAGWGHI---------QPFVDNDDAFIAKVMSLN 113
Query: 116 LIGTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLP 175
L G +IR L+ + + G ++N AS A G +G++ YSA+K G++ +
Sbjct: 114 LTGPIELIRAFFPLM------IEKKTGKIVNVASDAGRVGSLGESVYSAAKGGLIAFSKA 167
Query: 176 LARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
LAR+ A+ I V I PG TP+++ PE +++ +P R G PQE A + +
Sbjct: 168 LAREGARFNINVNAICPGPTDTPLLKSEPEKFLEAFLKVIPM-RRFGQPQEVADSIVFMA 226
Query: 236 QN--PMLNGETIRLDGSLRM 253
N + G+ + ++G + M
Sbjct: 227 SNRADYITGQVLSVNGGITM 246
>UniRef50_Q9F5J1 Cluster: SimJ1; n=5; Actinomycetales|Rep: SimJ1 -
Streptomyces antibioticus
Length = 273
Score = 107 bits (257), Expect = 3e-22
Identities = 86/257 (33%), Positives = 125/257 (48%), Gaps = 28/257 (10%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVTSE 62
VA+VTG G+G ATA+ L +G V + D +T S+ G A+ DVT
Sbjct: 29 VAIVTGAGRGIGAATAQRLAAEGATVAVVDRTEADTADTVASIRAAGGRALGIGCDVTVT 88
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
D V+ A+ T+ +FGRLD L+N AGV S V+ E + I V+L G
Sbjct: 89 DLVEAAVDRTVAEFGRLDVLVNNAGVTRDSLVFMMGDED------WDTVIDVHLNGAART 142
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
+R A + + G ++N +S+AA Q GQA Y+ +KA + G T LA ++
Sbjct: 143 VRAARRQMVRQGS------GRIVNLSSIAALGNQ-GQANYATAKAAIQGYTRTLAVELGP 195
Query: 183 QGIRVVTIAPGLFRTPMMEQL-------PEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
GI V IAPG T M + P K++ + VP R+G P++ A LV + +
Sbjct: 196 HGITVNAIAPGFIATTMTDDTARRMGSDPVALRKAVASRVPM-RRVGRPEDIAGLV-AFL 253
Query: 236 QNP---MLNGETIRLDG 249
P L G+TI +DG
Sbjct: 254 AGPDASYLTGQTIYVDG 270
>UniRef50_Q0RYT0 Cluster: Short-chain alcohol dehydrogenase; n=4;
Bacteria|Rep: Short-chain alcohol dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 241
Score = 107 bits (257), Expect = 3e-22
Identities = 76/224 (33%), Positives = 113/224 (50%), Gaps = 19/224 (8%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSEDDV 65
VA+VTGG+ G+G+ATAEL ++G RVV+ DL + + N F P+DVT D
Sbjct: 8 VAIVTGGARGIGRATAELFAEEGARVVVGDLREPEPFDHP-----NITFTPLDVTQLDSW 62
Query: 66 KEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVIRL 125
+ + + + GR+D L+N AG+ V +++ DLN + I VN G F +R
Sbjct: 63 QGLVDSVVAQHGRIDILVNNAGL-----VGSYEAIAKIDLNDWHKIIAVNQTGVFYGMRS 117
Query: 126 AVGLIGKNAPDADGQR-GVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQG 184
+ P Q G ++N +S+ G G +AY ASKA V M+ A G
Sbjct: 118 VL-------PTMQAQHAGSIVNVSSIWGIVGAAGVSAYQASKAAVRMMSKNAALSYVDDG 170
Query: 185 IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFA 228
IRV ++ PGL TPM++ E + A+ P R +P+E A
Sbjct: 171 IRVNSLHPGLASTPMIDAQDEAITADVIAATPM-KRAANPREIA 213
>UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protein;
n=1; Azoarcus sp. BH72|Rep: Short-chain dehydrogenase
family protein - Azoarcus sp. (strain BH72)
Length = 253
Score = 107 bits (257), Expect = 3e-22
Identities = 75/258 (29%), Positives = 126/258 (48%), Gaps = 18/258 (6%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPV 57
M + V +VTG SG+G+A AEL+ ++G V+ DL ++TA + G AV
Sbjct: 4 MLEQKVVIVTGAGSGIGRAAAELMAREGAIVIASDLKLDTVEDTAHRITLAGGRAVAVRT 63
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV ++ + + +FGRLD N AG+ +E FD I +NL
Sbjct: 64 DVAKLAELDALHDLAIAEFGRLDGAFNNAGIPGPGVALADHEEAAFDA-----LIAINLK 118
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
+ ++ + L+ G G ++NTASV G+ G + Y A+K V+G+T A
Sbjct: 119 AVWYGMKRQIELM------LPGGGGAIVNTASVGGIVGKPGLSVYCATKHAVIGLTKTAA 172
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQL--PEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
+ +G+RV + PG+ RTPM++Q+ +P + + R+G P+E A V ++
Sbjct: 173 LEYGSRGVRVNAVCPGVIRTPMVDQVIAGQPGAEEEWNRLQPIGRMGTPEELAETVVWLM 232
Query: 236 --QNPMLNGETIRLDGSL 251
+ +++G + DG L
Sbjct: 233 SPRASLVHGHALVADGGL 250
>UniRef50_A4QV37 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 274
Score = 107 bits (257), Expect = 3e-22
Identities = 76/205 (37%), Positives = 105/205 (51%), Gaps = 13/205 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAP--VDVTS 61
G LVTGG+ GLGKA AE ++ G VVICD+ + TAK LGE A VDVT
Sbjct: 23 GRTCLVTGGAGGLGKAVAEAFLRAGANVVICDIHEERLAQTAKELGELGPLASFVVDVTV 82
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
E V++ T +FG++D LIN AG+ F+ D++++ I VNL
Sbjct: 83 EKQVRQLFDDTAARFGKVDILINNAGLPD-----RFQPVGDVDMDLWDKVIAVNLTAPVL 137
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
+ + AV + A G G +IN ASVA+ G + AY ASK G++G+T A
Sbjct: 138 MSKFAVKSM---ATGTTG--GCIINMASVASKAGVLSGVAYVASKHGLLGITKSTAVHYR 192
Query: 182 KQGIRVVTIAPGLF-RTPMMEQLPE 205
+GI V + GL T M E + +
Sbjct: 193 DKGIGCVALLIGLMAETNMSEHITD 217
>UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=3; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus
furiosus
Length = 260
Score = 107 bits (257), Expect = 3e-22
Identities = 75/261 (28%), Positives = 124/261 (47%), Gaps = 21/261 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAV---FAPVDV 59
K VA+VTGG G+G A A+L + G +VV+ ++ G L E + F DV
Sbjct: 7 KNKVAIVTGGGQGIGAAIAQLFAENGAKVVLAEIDEEAGLEREAMLRERGLDVTFIKTDV 66
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
E+ VK ++ T++ +G +D L+N A + S ++ E+ ++ I+VNL G
Sbjct: 67 ADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEE------WERVIRVNLTGP 120
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
+ R A + K GV+IN AS A + YSASK G++ +T LA
Sbjct: 121 YICSRYAAEEMIKRGG------GVIINIASTRALMSEPDTEPYSASKGGLLALTHSLAIS 174
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQ---LPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ 236
+AK IRVV ++PG T ++ EP ++ ++ R+G P + A + +
Sbjct: 175 LAKYRIRVVAVSPGWIETSRWKKSKLRSEPKLRPIDHEQHPAGRVGDPMDIAHICAFLAD 234
Query: 237 NP---MLNGETIRLDGSLRMQ 254
N + G +DG + ++
Sbjct: 235 NEKAGFITGVNFVVDGGMTVK 255
>UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Thermotoga|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Thermotoga maritima
Length = 255
Score = 107 bits (256), Expect = 4e-22
Identities = 72/204 (35%), Positives = 110/204 (53%), Gaps = 17/204 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVIC----DLPSTKGQNTAKSLGENAVFAPVD 58
+G VALVTGGS GLG A+ L + G VV+ + S Q + G + D
Sbjct: 8 RGRVALVTGGSRGLGFGIAQGLAEAGCSVVVASRNLEEASEAAQKLTEKYGVETMAFRCD 67
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V++ ++VK+ L+ +KFG+LD ++N AG+ +R + + F L+ F+ I+VNL G
Sbjct: 68 VSNYEEVKKLLEAVKEKFGKLDTVVNAAGI---NRRH---PAEEFPLDEFRQVIEVNLFG 121
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQ-AAYSASKAGVVGMTLPLA 177
T+ V R A L+ + +IN S+ + + +AY+ASK GV +T LA
Sbjct: 122 TYYVCREAFSLL------RESDNPSIINIGSLTVEEVTMPNISAYAASKGGVASLTKALA 175
Query: 178 RDMAKQGIRVVTIAPGLFRTPMME 201
++ + GIRV IAPG +RT M E
Sbjct: 176 KEWGRYGIRVNVIAPGWYRTKMTE 199
>UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=1; Pirellula sp.|Rep:
3-oxoacyl-[acyl-carrier protein] reductase -
Rhodopirellula baltica
Length = 268
Score = 107 bits (256), Expect = 4e-22
Identities = 67/199 (33%), Positives = 108/199 (54%), Gaps = 13/199 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAP---VDVT 60
G VAL+TGG+SG+G ATA + ++G + + D+ S + + A L E V VD+
Sbjct: 7 GNVALITGGASGIGLATARMFAEEGCSLQLWDV-SPQVEEAASELREQGVKVGTQIVDIV 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
E+ VK+A+ +D+ GRLD +++CA + S + F P D ++ T++VN+IG
Sbjct: 66 DEEQVKQAVGSCMDEHGRLDHVVHCAAIGSGKFGFPFTHVAPSD---WKRTLEVNVIGMA 122
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
N+ A L P + + G + AS+A G YSASKA + +A+D+
Sbjct: 123 NI---AAALA---PPLVEQRSGSFVFLASIAGQMGSQTDPPYSASKAANINFAQCMAKDL 176
Query: 181 AKQGIRVVTIAPGLFRTPM 199
A +RV T+ PG+ +TP+
Sbjct: 177 APHNVRVNTVCPGMVKTPL 195
>UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=6;
Bacteroides|Rep: 7-alpha-hydroxysteroid dehydrogenase -
Bacteroides fragilis
Length = 259
Score = 107 bits (256), Expect = 4e-22
Identities = 73/256 (28%), Positives = 117/256 (45%), Gaps = 16/256 (6%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN-AVFAPV--D 58
F+ + ++TG + G+G +T +V +GG+VVI D K A L + A PV
Sbjct: 4 FENKIIIITGAAGGIGASTTRRIVSEGGKVVIADYSREKADQFAAELSNSGADVRPVYFS 63
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
T KE + T+ ++G++D L+N G + R N + D++ F +NL
Sbjct: 64 ATELKSCKELITFTMKEYGQIDVLVNNVGGTNPRRDTNI---ETLDMDYFDEAFHLNLSC 120
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
T + +L + ++ G ++N AS++ Y ASKAGV+ +T +A
Sbjct: 121 TMYLSQLVIPIMSTQGG------GNIVNVASISGITADSNGTLYGASKAGVINLTKYIAT 174
Query: 179 DMAKQGIRVVTIAPGLFRTP-MMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
K+ IR +APGL TP + L E K P LG PQ+ A + +
Sbjct: 175 QTGKKNIRCNAVAPGLILTPAALNNLNEEVRKIFLGQCATP-YLGEPQDVAATIAFLASE 233
Query: 238 P--MLNGETIRLDGSL 251
+ G+TI +DG L
Sbjct: 234 DARYITGQTIVVDGGL 249
>UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase;
n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein
reductase - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 249
Score = 107 bits (256), Expect = 4e-22
Identities = 82/256 (32%), Positives = 131/256 (51%), Gaps = 19/256 (7%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKS-LGEN-AVFAPVDVT 60
K VA++TGG +G+G AE V++G +VV+ + G A + G++ ++F DV+
Sbjct: 6 KDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAVAKFGDDVSLFVQQDVS 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
E D ++ + T+ KFGR+D L+N AG+ + + DL +Q I VNL F
Sbjct: 66 KEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAI-----EDLDLADWQKVIDVNLTANF 120
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+ A+ + K DA +G +IN +SVA G AYSASK G +T A ++
Sbjct: 121 LGEKAAIKAM-KQTADA---KGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALNL 176
Query: 181 AKQG--IRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEF--ALLVQSIIQ 236
A++G IRV ++ PG T + +PE A K + A++P +G PQ+ + +
Sbjct: 177 AQRGIDIRVNSVHPGWIDTSI---VPEAARKQIIATIPV-GHMGQPQDIGEVCVYLGSDE 232
Query: 237 NPMLNGETIRLDGSLR 252
+ NG +DG R
Sbjct: 233 SRFANGAEFTVDGGQR 248
>UniRef50_A5P615 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Methylobacterium sp. 4-46|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Methylobacterium sp. 4-46
Length = 252
Score = 107 bits (256), Expect = 4e-22
Identities = 84/252 (33%), Positives = 117/252 (46%), Gaps = 14/252 (5%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPST-KGQNTAKSLGENA--VFAPVDV 59
+G LVTG +SG+G A A L + G V + L +G A L V A
Sbjct: 7 RGKSVLVTGAASGIGLAAATLFARCGAAVALNHLAEDGRGPEAAARLAAEGYRVTAVAGS 66
Query: 60 TSEDDVKEALQ-ITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
++ EAL L+ G LD LIN AG + ++ F +Q + NLIG
Sbjct: 67 VAQPGEAEALVGRALEALGGLDVLINNAGTSGTAQPIPFADLDAMTEEFWQTILSTNLIG 126
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
+ R A AP +RG ++NTASVA + AYSASKAG+V +T LAR
Sbjct: 127 PYRCARAA-------APALRARRGAIVNTASVAGLGRRGSSIAYSASKAGLVNLTRSLAR 179
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN- 237
+A + +RV +APGL TP E P K S +RL P++ A + +
Sbjct: 180 ALAPE-VRVNAVAPGLVETPWTEAWPAER-KQATLSRTLLARLAKPEDIAEAMLFLAAGA 237
Query: 238 PMLNGETIRLDG 249
+ GET+ +DG
Sbjct: 238 AYVTGETLVVDG 249
>UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid
dehydrogenase; n=1; Bacillus sp. B14905|Rep: Putative
7-alpha-hydroxysteroid dehydrogenase - Bacillus sp.
B14905
Length = 267
Score = 107 bits (256), Expect = 4e-22
Identities = 83/253 (32%), Positives = 129/253 (50%), Gaps = 22/253 (8%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVTSE 62
VALVTGG+SG+G + A LL K+G +VVI D Q A SL G A +D
Sbjct: 8 VALVTGGASGIGLSAATLLAKEGAKVVIADFNIEGAQEAAHSLVKEGYEASAIFLDAGDA 67
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
++ A+ T++++G L L N G+ + + + DL+ + + VNL
Sbjct: 68 SSIEAAVNFTVEQYGTLTVLFNNVGLTNLQKDLDVVN---IDLDEWDRLVNVNLKSILLG 124
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
R A+ + K A G G +INTAS+AAF + AY A+KAGVV MT +A K
Sbjct: 125 SRFAIPHMQK----AGG--GSIINTASMAAFASDQIRTAYGATKAGVVNMTKNIATQYGK 178
Query: 183 QGIRVVTIAPGLFRTPMME-QLPEP--AIKSLEASVPFPSR---LGHPQEFALLVQSIIQ 236
IR +APGL TP + +P+ AI S ++P+ +GH A++ + +
Sbjct: 179 DKIRCNAVAPGLILTPAAKNNMPDEMLAIYSKFNALPYHGEADDIGH----AVVFLASDE 234
Query: 237 NPMLNGETIRLDG 249
+ + G+T++++G
Sbjct: 235 SKFMTGQTMQIEG 247
>UniRef50_A2ULL1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Escherichia coli B|Rep: Short-chain
dehydrogenase/reductase SDR - Escherichia coli B
Length = 250
Score = 107 bits (256), Expect = 4e-22
Identities = 83/256 (32%), Positives = 124/256 (48%), Gaps = 22/256 (8%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL--GE-NAVFAPVD 58
F G V LVTGG+ G+GK A+ +G VI D G+ TA L G+ ++F D
Sbjct: 4 FAGKVVLVTGGAHGIGKGIAKQFADRGAHTVIVDYNEENGKATAAELTFGDVKSLFIKTD 63
Query: 59 VTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIG 118
V+ + + + FGR+D LI AGVA A++V N E+ + TI +NL G
Sbjct: 64 VSDPQALVDVREKVFATFGRIDVLILNAGVAFANKVNNISFEE------WNKTIAINLSG 117
Query: 119 TFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLAR 178
FN ++ D +G ++ +S +A G G +Y ASKAG G+ LA+
Sbjct: 118 LFNTVKAFYD-------DFLTNKGSIVYISSGSALSGTGGGVSYPASKAGGEGLIRGLAK 170
Query: 179 DMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEA---SVPFPSRLGHPQEFALLVQSII 235
++ +G+ V IAP L T M ++ P L+A +P RLG + A L +
Sbjct: 171 ELGPKGVNVNAIAPRLIDTGEMMRVNYPTQADLDAVLEKIPV-RRLGTIDDVANLAIFLA 229
Query: 236 --QNPMLNGETIRLDG 249
N + G+TI +DG
Sbjct: 230 DKDNSYIQGQTILMDG 245
>UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain
dehydrogenase/reductase SDR - Verminephrobacter eiseniae
(strain EF01-2)
Length = 265
Score = 107 bits (256), Expect = 4e-22
Identities = 85/257 (33%), Positives = 123/257 (47%), Gaps = 24/257 (9%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL---GENAVFAPVDVT 60
G VAL+TG SG+G+ATA L +G ++V+CDL GQ T +++ G A+F DV
Sbjct: 15 GKVALITGAGSGIGRATALLFATEGAQIVVCDLDPEGGQATVRAIEQAGAQALFVQADVA 74
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
D A+Q TL F RLD L N AG+ + V + E +D + VN+ F
Sbjct: 75 QAADCARAVQQTLRHFARLDVLFNNAGITCRANVVD-TSEADWDA-----VMAVNVKSIF 128
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
+ R AV ++ A+ G +IN S G +Y A+K VV MT +A D
Sbjct: 129 LMSRQAVPVM------AEQGGGSIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMALDH 182
Query: 181 AKQGIRVVTIAPGLFRTPMMEQ------LPEPAIKSLEASVPFPSRLGHPQEFALLVQSI 234
Q IRV ++ PG T M+ LPE A+ S P R+G +E A +V +
Sbjct: 183 GPQRIRVNSVCPGDTDTAMLRDEARQLGLPETALVLAGNSRPL-MRVGRAEEIAQVVLFL 241
Query: 235 I--QNPMLNGETIRLDG 249
++ + G +DG
Sbjct: 242 ASDRSSFVTGSAYVVDG 258
>UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=18; Actinomycetales|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
KMS)
Length = 257
Score = 107 bits (256), Expect = 4e-22
Identities = 79/256 (30%), Positives = 123/256 (48%), Gaps = 21/256 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
KG VA++TGG+SG+G ATA+ + +G +VI D+ G+ A L N F VDV+ +
Sbjct: 8 KGKVAVITGGASGIGLATAKRMRAEGATIVIGDIDPATGKTVADDL--NGTFVQVDVSDQ 65
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
V ++ G +D N AG++ + ++ + +NL F
Sbjct: 66 VAVDALFDTAAEEHGSVDIAFNNAGISPPED----DLIEVTGIDAWDRVQDINLKSVFFC 121
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQ-IGQAAYSASKAGVVGMTLPLARDMA 181
+ A+ + Q+G +INTAS A +G Q +Y+ASK GV+ M+ L A
Sbjct: 122 CKAALRHM------VPAQKGSIINTASFVAVNGSATSQISYTASKGGVLAMSRELGIQYA 175
Query: 182 KQGIRVVTIAPGLFRTPMMEQL----PEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
+QGIRV + PG TP++++L PE A + L VP R P E A V + +
Sbjct: 176 RQGIRVNALCPGPVNTPLLQELFAKDPERAARRL-VHVPM-GRFAEPAELAAAVAFLASD 233
Query: 238 --PMLNGETIRLDGSL 251
+ G T +DG +
Sbjct: 234 DASFITGSTFLVDGGI 249
>UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;
n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase
SSP0419 - Staphylococcus saprophyticus subsp.
saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 234
Score = 107 bits (256), Expect = 4e-22
Identities = 72/211 (34%), Positives = 114/211 (54%), Gaps = 16/211 (7%)
Query: 6 VALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGEN--AVFAP--VDVTS 61
VA+VTG SSG+G + AE L QG +VV+ ++ AK + +N AV VDVT
Sbjct: 8 VAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSIVDVTH 67
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
+++V E ++ T +KFG++D L+N AG+ +S + D+ ++ I VN+ GT
Sbjct: 68 KEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEG------DVEAWEAMIDVNIKGTLY 121
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
I + + + G +IN AS++ F+ YSASKA V +T L +++A
Sbjct: 122 TINAVLPSM------LNQSSGHIINIASISGFEVTKKSTLYSASKAAVHSITQGLEKELA 175
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLE 212
K G+RV +I+PG+ TP+ A K L+
Sbjct: 176 KTGVRVTSISPGMVDTPLSGDTDWGARKKLD 206
>UniRef50_Q985G9 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=2; Proteobacteria|Rep: 3-oxoacyl-(Acyl
carrier protein) reductase - Rhizobium loti
(Mesorhizobium loti)
Length = 239
Score = 106 bits (255), Expect = 5e-22
Identities = 80/230 (34%), Positives = 121/230 (52%), Gaps = 22/230 (9%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTS 61
F G A+VTGG+ G+G+A A L G V I D+ + + T +SL VDVT
Sbjct: 7 FTGRTAIVTGGARGIGRAIAHKLSLSGADVWIWDIEPVELEGT-RSLS-------VDVTK 58
Query: 62 EDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFN 121
D+V +AL I + + G +D L+N AG +K + F+ +Q +QVNL+GTF
Sbjct: 59 RDNVMQALTI-MGEVG-VDILVNNAGWLGG-----YKPFEEFEPAEWQRILQVNLLGTFE 111
Query: 122 VIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
V + L+ + +G ++N S+A +G AAYSA+ AGV+ T L+R+++
Sbjct: 112 VTHRVLPLMRRAG------KGRIVNMGSLAGKEGLPSLAAYSAASAGVIAFTKALSREVS 165
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLV 231
IRV IAPG T ++ L + ++ ++ P RLG P E A LV
Sbjct: 166 DTDIRVNCIAPGPIDTRLIRDLGNETVDAMISASPL-KRLGDPNEVAALV 214
>UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Carboxydothermus
hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Carboxydothermus
hydrogenoformans (strain Z-2901 / DSM 6008)
Length = 249
Score = 106 bits (255), Expect = 5e-22
Identities = 79/252 (31%), Positives = 130/252 (51%), Gaps = 18/252 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENA--VFA-PVDVT 60
G V +VTGGS G+G ATA+ + ++G +VVI + +G+ A L E V++ P DV
Sbjct: 6 GKVGIVTGGSKGIGFATAKRIAEEGAKVVIANRNKEEGEKAALQLREKGLEVYSIPCDVG 65
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
D+K+ + ++GR+D L+NCAGV + + +E D N + +NL GTF
Sbjct: 66 KVADIKKLVSEVYGRYGRIDILVNCAGVNVRKPIEEYTEE---DWNYM---VDINLKGTF 119
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
A GK+ + GV++N AS+ A + + Y+ +K GV +T LA +
Sbjct: 120 ----FACIEAGKHM--IAQKEGVIVNLASIQAEEVLPERGIYATTKGGVKQLTKALAVEW 173
Query: 181 AKQGIRVVTIAPGLFRTPMMEQ-LPEPAIKSLEASVPFPSRLGHPQEFALLVQSII--QN 237
AK IRV ++P +T M+E+ L +P +L + R G P+E A + ++ +
Sbjct: 174 AKYNIRVNAVSPAFIKTEMVEKVLQDPYWGNLIINKTPMRRPGTPEEVAEAILFLVSPKA 233
Query: 238 PMLNGETIRLDG 249
+ G + +DG
Sbjct: 234 SYITGINLLVDG 245
>UniRef50_Q11C87 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Mesorhizobium sp. (strain
BNC1)
Length = 247
Score = 106 bits (255), Expect = 5e-22
Identities = 77/253 (30%), Positives = 124/253 (49%), Gaps = 23/253 (9%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLP--STKGQNTAKSLGENAVFAPVDVT 60
K V ++TGG+SG+G+ + V+ G + DLP + S+ + F +DVT
Sbjct: 2 KKKVLVLTGGASGIGRGILDHAVRAGWHTAVFDLPGEALDALRDTFSMDDVTTFG-IDVT 60
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
E+ V A++ + F R+D ++NCAG+ F + P F+ + VN+IG+F
Sbjct: 61 DENAVDAAVRKVAEPFERIDGVVNCAGIGQN---IPFNETTPAQ---FRKVLDVNVIGSF 114
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
V + AV + G V+N SV+ G +G+ AY ASK V MT +A ++
Sbjct: 115 IVAQSAVRHMSN---------GSVVNITSVSGIQGSVGRVAYGASKGAVNTMTRIMAVEL 165
Query: 181 AKQGIRVVTIAPGLFRTPMMEQL-PEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPM 239
A G+RV IAPG TPM ++ E ++ VP R E A + ++ + +
Sbjct: 166 APHGVRVNAIAPGPVETPMAQKWHDEKTRNDWKSRVPL-GRYASVDEIASMAMVLLDDNL 224
Query: 240 ---LNGETIRLDG 249
+NG+ I +DG
Sbjct: 225 SSYVNGQVIAVDG 237
>UniRef50_A0L6T4 Cluster: Acetoacetyl-CoA reductase; n=24;
Bacteria|Rep: Acetoacetyl-CoA reductase - Magnetococcus
sp. (strain MC-1)
Length = 247
Score = 106 bits (255), Expect = 5e-22
Identities = 77/257 (29%), Positives = 129/257 (50%), Gaps = 22/257 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVV-ICDLPSTKGQNTAKSLGE----NAVFAPV 57
K VA+V+GG+ G+G L QG +V C + K E V V
Sbjct: 2 KDRVAMVSGGAGGIGTEIVRSLHAQGYKVASTCTVMECARVQQWKKERELEHVEVVMVEV 61
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DV + + + ++ + G +D L+N AG+ + EQ +Q+ I VNL
Sbjct: 62 DVRNYESCLKGVEEVESRLGPIDVLVNNAGITKDGVMKKMSPEQ------WQSVIDVNLT 115
Query: 118 GTFNVIRLAV-GLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPL 176
GT+N+ + + G++ + Q G +IN +SV GQ GQ Y+A+KAG+ G+T+ L
Sbjct: 116 GTWNMTKAVLDGMLER-------QYGRIINISSVNGQKGQFGQVNYAAAKAGMHGITMSL 168
Query: 177 ARDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSII- 235
A+++A++GI V T++PG T M+ + E + A++P RLG P+E A LV +
Sbjct: 169 AQEVARKGITVNTVSPGYIGTDMVMAIDEEIRNKIIATIPV-GRLGKPEEIARLVTFLAA 227
Query: 236 -QNPMLNGETIRLDGSL 251
++ + G ++G +
Sbjct: 228 EESGFMTGADFSINGGM 244
>UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza
sativa|Rep: Os03g0833100 protein - Oryza sativa subsp.
japonica (Rice)
Length = 274
Score = 106 bits (255), Expect = 5e-22
Identities = 71/212 (33%), Positives = 108/212 (50%), Gaps = 11/212 (5%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSL-GENAVFAPVDVTSE 62
G VA+VTGG+SG+G+A A L G VVI D+ G+ A S+ G + DVT E
Sbjct: 17 GKVAIVTGGASGIGEAAARLFASCGATVVIADVQDELGEAVAASVAGGGCRYVRCDVTDE 76
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
V+ A+ + + GRLD +++ AGV + DL + VN G
Sbjct: 77 AQVEAAVAAAVAEHGRLDVMVSNAGVLLPTGPV-----VDMDLAALDRVMSVNFRGAAAC 131
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
++ A A + G RG ++ TASVA+ G G AAY+ASK V+G+ A ++ +
Sbjct: 132 VKHAA-----RAMVSRGTRGAIVCTASVASCQGGFGPAAYTASKHAVLGLVRAAAGELGR 186
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEAS 214
G+RV ++PG TP+ L + + +EA+
Sbjct: 187 HGVRVNCVSPGGVATPLSCGLTGMSPEEMEAA 218
>UniRef50_Q93HB3 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=1; Streptomyces avermitilis|Rep:
3-oxoacyl-(Acyl carrier protein) reductase -
Streptomyces avermitilis
Length = 246
Score = 106 bits (254), Expect = 6e-22
Identities = 78/250 (31%), Positives = 118/250 (47%), Gaps = 16/250 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVI-CDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
G VALVTG S LG A A +L +G R+ + + + A L + DV
Sbjct: 8 GRVALVTGASGALGAAVARVLDHRGYRLALHYTNGEDQARKVAAKLSGPSTLVRADVADW 67
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
++ + + G + L+N + R Q D + T+ VNLIGTF+
Sbjct: 68 AATRDMVDRVRAELGGISVLVNTGAI----RRDGLMATQSVD--DWTRTVAVNLIGTFHT 121
Query: 123 IRLAVGLIGKNAPDA-DGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
R A+ PD G+ G +IN S A G GQ AYSASKAGV+GMT LA +
Sbjct: 122 CRAAL-------PDMLRGRWGRIINVVSPAGLLGSRGQTAYSASKAGVLGMTRSLALECG 174
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLN 241
+ + V ++PGL T + E++P +L A F R+G P E A ++ ++ +
Sbjct: 175 RFNVTVNALSPGLMATALTEEVPAEVRATLVARTAF-GRMGTPDEVARGIELLLDADYMT 233
Query: 242 GETIRLDGSL 251
G+ + +DG +
Sbjct: 234 GQVLSIDGGM 243
>UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 250
Score = 106 bits (254), Expect = 6e-22
Identities = 82/251 (32%), Positives = 120/251 (47%), Gaps = 14/251 (5%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSE 62
+G VA+VTG ++G+G A A V +G +VVI D+ + GQ A LGE A F DV+
Sbjct: 8 EGKVAIVTGAANGIGVAIATRFVTEGAKVVIADIDAG-GQGVAAELGERATFFSTDVSDP 66
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ + T+ FG L L N AGV+ R F + DL F+ + V+L G
Sbjct: 67 VQTQALVDFTIRHFGGLHVLCNNAGVSGGLR--RFLDD---DLRDFERVVAVDLYGVMAC 121
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
R A ++ D G G ++N AS A IG Y A+KAGVV T LA ++ +
Sbjct: 122 SRSAA----RHMVDHGG--GAIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCLAVEVGE 175
Query: 183 QGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQNPMLNG 242
GIR IAP T + + + L+ +P R G E AL + S + + G
Sbjct: 176 HGIRANCIAPANISTDINAAFDKATVIRLQ-PLPHQGRTGDIAEAALYLAS-DRAAHVTG 233
Query: 243 ETIRLDGSLRM 253
+ +DG + +
Sbjct: 234 LVLAVDGGMSL 244
>UniRef50_Q8YDW1 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN)
REDUCTASE; n=6; cellular organisms|Rep:
3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella
melitensis
Length = 245
Score = 105 bits (253), Expect = 8e-22
Identities = 74/256 (28%), Positives = 127/256 (49%), Gaps = 20/256 (7%)
Query: 2 FKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPV--DV 59
F+ ++TG + G+G+A AEL G +V+ DL A SLG A + D
Sbjct: 5 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADA 64
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
+S DD ++ + + +++FG +D L+ G+ A F + D + TI +NL G
Sbjct: 65 SSADDAEKTVALAMERFGGIDFLVPSVGIYQAKP---FAEMSDAD---WHRTISINLDGV 118
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F + + A+ + +++ ++ AS+AA+ G A Y A+K +V MT L+R+
Sbjct: 119 FYLCKRALPALKEDSS--------IVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRE 170
Query: 180 MAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQ--N 237
+A + RV +APG+ TPM +L + + P RLG P E A ++ +
Sbjct: 171 LAPK-TRVNGVAPGIIETPMTSELLKTRMDETMTQTPL-KRLGKPSEIASVIAFLCSPAA 228
Query: 238 PMLNGETIRLDGSLRM 253
+ GETI+++G + M
Sbjct: 229 SFVTGETIQVNGGIYM 244
>UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Geobacter|Rep: Short-chain dehydrogenase/reductase
SDR - Geobacter metallireducens (strain GS-15 / ATCC
53774 / DSM 7210)
Length = 255
Score = 105 bits (253), Expect = 8e-22
Identities = 72/257 (28%), Positives = 124/257 (48%), Gaps = 19/257 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICD-LPSTKGQNTAKSLGENAVFAPVDVTSE 62
G VA++TGG+ G+G A A L K+G ++VI D L K K+ G +A++ DV+S+
Sbjct: 6 GKVAIITGGAQGIGAAYAVGLAKEGAKIVIADVLDGAKAVEAVKAAGSDAIYVKTDVSSQ 65
Query: 63 DDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNV 122
+ Q +KFG +D L+N A + + + F + P + F +++N++G FN
Sbjct: 66 EQCDAMAQAAAEKFGSVDILLNNAAIFGSIVLKPFTECTPQE---FMKVMEINVLGQFNC 122
Query: 123 IRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAK 182
++ P + G +IN +S + +G G Y ASK ++ +T +AR++
Sbjct: 123 MKAVF-------PHMKARGGKIINISSSSIIEGVPGMPHYVASKGAIMALTRSMARELGD 175
Query: 183 QGIRVVTIAPGLFRT------PMMEQLPEPAIKSLEASVPFPSRLGHPQEF--ALLVQSI 234
I V TIAPG + ++L P ++ L+ + R P++ L S
Sbjct: 176 YKINVNTIAPGFTHSDGGNSFDKNKKLDLPPLEELQINARCLKREAVPEDLIGLALFLSS 235
Query: 235 IQNPMLNGETIRLDGSL 251
+ + G+ I DG L
Sbjct: 236 DDSAFITGQMIVHDGGL 252
>UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Sphingomonadaceae|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 266
Score = 105 bits (253), Expect = 8e-22
Identities = 76/256 (29%), Positives = 123/256 (48%), Gaps = 17/256 (6%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGE---NAVFAPVDVT 60
G V +VTG SG+G+A+A + +QGGRVV+ D+ ++ G+ T +++ +A+F ++
Sbjct: 7 GKVCIVTGSGSGMGRASAMEMARQGGRVVVTDINTSAGEETVEAIRAEKGDAIFIACNLR 66
Query: 61 SEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTF 120
++K +Q T D FG +D L N A + E I+ +VNL +
Sbjct: 67 KAHEIKVLMQKTADHFGGIDVLHNNAAIHETDLTDKTSIED-LPEEIWDAVYEVNLKALW 125
Query: 121 NVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDM 180
R AV + + + ++N AS +F AY A+K GV+ +T A D+
Sbjct: 126 LTTRYAVPWLKLS------KGAAIVNVASTGSFVSYPQAGAYCATKGGVLLLTKATAVDL 179
Query: 181 AKQGIRVVTIAPGLFRTPMMEQL-----PEPAIKSLEASVPFPSRLGHPQEFALLVQSII 235
AK GIR PG TPM+++ + AI S+ RLG P+E A L +
Sbjct: 180 AKYGIRCNCYCPGAIETPMLQKYLDAAEDKKAIMSVLTGAHLIPRLGKPEEVAKLACFLA 239
Query: 236 --QNPMLNGETIRLDG 249
+ +NG + +DG
Sbjct: 240 SDDSSFINGASYVIDG 255
>UniRef50_Q3W9J0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 259
Score = 105 bits (253), Expect = 8e-22
Identities = 67/200 (33%), Positives = 103/200 (51%), Gaps = 10/200 (5%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G +A+VTGG+ +G A + L ++G +VV+ DL ++ A ++G A+ DV++ D
Sbjct: 7 GKIAVVTGGAGVIGAAVCDRLAREGAKVVVADLDEAAAKHVADTVGGGAIGVAADVSTPD 66
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
+ + + FGRLD L AGV + FD + VN++G F
Sbjct: 67 GATACVDVAVAAFGRLDLLHANAGVECV-----VQPVADFDPGDYHKVFGVNVLGAFLSA 121
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARDMAKQ 183
+ AV + A G G ++ TAS+AA G G + Y+ASK V G+ LA ++A
Sbjct: 122 QAAVRQL-----TAQGGGGQILFTASIAALMGTGGTSVYNASKHAVHGIARCLALEVAGT 176
Query: 184 GIRVVTIAPGLFRTPMMEQL 203
GIRV T+APG + MM+ L
Sbjct: 177 GIRVNTLAPGAVESRMMDAL 196
>UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=4; Actinomycetales|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
sp. (strain RHA1)
Length = 260
Score = 105 bits (253), Expect = 8e-22
Identities = 79/250 (31%), Positives = 123/250 (49%), Gaps = 19/250 (7%)
Query: 4 GLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTKGQNTAKSLGENAVFAPVDVTSED 63
G A+VTG S G+G A A+ + GG VV+ A +G A+ E+
Sbjct: 8 GRTAIVTGASRGIGLAVAKAIAAAGGNVVLTSRSQESADAAAAQVGGTAIGIAAHAVDEE 67
Query: 64 DVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGTFNVI 123
+ + +TL++FG LD L+N AG +F D F T VNL
Sbjct: 68 AARRCVDVTLERFGSLDILVNNAGTNP-----SFGPVIDQDHARFAKTFDVNLWAPV--- 119
Query: 124 RLAVGLIGKNAPDADGQRGVVINTASVA--AFDGQIGQAAYSASKAGVVGMTLPLARDMA 181
L GL+ K G G V+NTAS+ AF+ IG Y+ASKA ++ +T LA +++
Sbjct: 120 -LWTGLVTKAWMGEHG--GAVVNTASIGGMAFEANIG--LYNASKAALIHVTKQLALELS 174
Query: 182 KQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN--PM 239
+ +RV +APG+ RT + E L + +++ AS R+G P++ A V ++ +
Sbjct: 175 PK-VRVNAVAPGVVRTKLAEALWKEHEQAVSASTAL-GRIGEPEDIASAVAFLVSDAASW 232
Query: 240 LNGETIRLDG 249
+ GET+ +DG
Sbjct: 233 ITGETMVIDG 242
>UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=9; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
sp. (strain RHA1)
Length = 249
Score = 105 bits (253), Expect = 8e-22
Identities = 79/241 (32%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 1 MFKGLVALVTGGSSGLGKATAELLVKQGGRVVICDLPSTK--GQNTAKSLGE-NAVFAPV 57
+ +G A+VTG +SG+G A A+ +G +++ D + + S GE AV V
Sbjct: 3 ILEGRTAIVTGAASGIGAAIADAYAAEGAHLLLADRDEERLAAAVSRYSEGEAKAVGVVV 62
Query: 58 DVTSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLI 117
DVT D K + L +FG LD L+NCAG+ + + D+ + I V+L
Sbjct: 63 DVTDPDQTKMMVDRCLAEFGALDILVNCAGLLTEVPLAEM------DVATWDEMISVDLR 116
Query: 118 GTFNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLA 177
F R AV + A G G +IN +S G +G Y A+KAGV+G+T LA
Sbjct: 117 SVFLCCRWAVPHML-----AQGS-GRIINISSQLGIKGGVGLVHYCAAKAGVIGLTRALA 170
Query: 178 RDMAKQGIRVVTIAPGLFRTPMMEQLPEPAIKSLEASVPFPSRLGHPQEFALLVQSIIQN 237
R++A G+ V IAPG TP+ + E ++ EA +P R G P E A + +
Sbjct: 171 RELAPSGVLVNAIAPGPVWTPLFAGITEDWRQAKEAELPL-GRFGLPHEIAPTAVLLASD 229
Query: 238 P 238
P
Sbjct: 230 P 230
>UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family precursor; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family precursor - Syntrophomonas wolfei subsp. wolfei
(strain Goettingen)
Length = 252
Score = 105 bits (253), Expect = 8e-22
Identities = 85/258 (32%), Positives = 127/258 (49%), Gaps = 22/258 (8%)
Query: 3 KGLVALVTGGSSGLGKATAELLVKQGGRVVICDL---PSTKGQNTAKSLGENAVFAPVDV 59
KG VA++TGG +G+G+A A L +G RVV+ P + + K G + P DV
Sbjct: 4 KGKVAVITGGGTGIGRAAAIALAAEGARVVVMGRRPEPLNETVDIVKERGGEGLAIPSDV 63
Query: 60 TSEDDVKEALQITLDKFGRLDALINCAGVASASRVYNFKKEQPFDLNIFQNTIQVNLIGT 119
T +D+++A + +GRLD L+N AG A FK L F QV+L
Sbjct: 64 TKIEDIEKARDEVRETYGRLDILVNNAGSAL------FKPFMKTSLEDFDRIYQVDLRSV 117
Query: 120 FNVIRLAVGLIGKNAPDADGQRGVVINTASVAAFDGQIGQAAYSASKAGVVGMTLPLARD 179
F V +L + L+ +G G +IN AS+ G +AY A K GVV +T LA +
Sbjct: 118 FAVSQLMLPLM------LEGGGGSIINIASILGVLGGKSSSAYCAMKGGVVQLTRALAAE 171
Query: 180 MAKQGIRVVTIAPGLFRTPMME-QLP--EPAIKSLEASVPFP-SRLGHPQEF--ALLVQS 233
+ + IRV + P TPMME +L E K + + FP RL +P++ ++L +
Sbjct: 172 LGPE-IRVNCLCPSHIITPMMEDELSRIESKGKMDKLTKMFPMKRLAYPEDMTGSILFYA 230
Query: 234 IIQNPMLNGETIRLDGSL 251
+ L G + +DG L
Sbjct: 231 SDDSKWLTGNILMIDGGL 248
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.135 0.379
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 267,019,103
Number of Sequences: 1657284
Number of extensions: 10911953
Number of successful extensions: 44429
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 3517
Number of HSP's successfully gapped in prelim test: 1620
Number of HSP's that attempted gapping in prelim test: 33777
Number of HSP's gapped (non-prelim): 5934
length of query: 255
length of database: 575,637,011
effective HSP length: 99
effective length of query: 156
effective length of database: 411,565,895
effective search space: 64204279620
effective search space used: 64204279620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)
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