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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000496-TA|BGIBMGA000496-PA|IPR000109|TGF-beta receptor,
type I/II extracellular region
         (642 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_40184| Best HMM Match : PTR2 (HMM E-Value=0)                       220   2e-57
SB_21872| Best HMM Match : No HMM Matches (HMM E-Value=.)             143   3e-34
SB_1733| Best HMM Match : ATP-synt_C (HMM E-Value=4.5)                110   4e-24
SB_56680| Best HMM Match : PTR2 (HMM E-Value=3e-06)                   105   1e-22
SB_15813| Best HMM Match : No HMM Matches (HMM E-Value=.)              68   3e-11
SB_25052| Best HMM Match : Prenyltrans (HMM E-Value=6.5)               51   2e-06
SB_14765| Best HMM Match : No HMM Matches (HMM E-Value=.)              50   6e-06
SB_15812| Best HMM Match : No HMM Matches (HMM E-Value=.)              46   7e-05
SB_37034| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.076
SB_49457| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   0.40 
SB_5552| Best HMM Match : No HMM Matches (HMM E-Value=.)               33   0.53 
SB_29473| Best HMM Match : CASP_C (HMM E-Value=6.5)                    33   0.71 
SB_16510| Best HMM Match : No HMM Matches (HMM E-Value=.)              30   5.0  
SB_6822| Best HMM Match : No HMM Matches (HMM E-Value=.)               30   5.0  
SB_21701| Best HMM Match : No HMM Matches (HMM E-Value=.)              29   8.7  
SB_11387| Best HMM Match : MFS_1 (HMM E-Value=4.4e-06)                 29   8.7  

>SB_40184| Best HMM Match : PTR2 (HMM E-Value=0)
          Length = 421

 Score =  220 bits (538), Expect = 2e-57
 Identities = 109/215 (50%), Positives = 151/215 (70%), Gaps = 7/215 (3%)

Query: 83  LVYATGSVLISLTAMPPIGLPQFELTILALLLIAFGTGGIKPCVSAFGGDQFKLPEQAKY 142
           ++YA G++++++T++P I L ++      LLLIA GTGGIKPCVSAFGGDQF   ++   
Sbjct: 1   MIYAFGNIVVAITSIPAI-LAKYWCHD-GLLLIAIGTGGIKPCVSAFGGDQFSAAQE-NL 57

Query: 143 LGYYFSLFYFAINAGSLISTFLTPILRADVHCFGDSDCFSLAFGVPGILMVVSILIFVAG 202
           L  +FS+FYFAIN GSL+S  +TPILR DV+  G +  + LAFGVP ILM+ S+ +F  G
Sbjct: 58  LQSFFSIFYFAINLGSLLSMIVTPILRGDVNGLG-TIAYPLAFGVPAILMITSVGLFWCG 116

Query: 203 RRLYVIKNPSGNVLGKVSTCVGHAVVKSIKNKQ---KRDHWLDHADEKYDKSLIEDIKSL 259
           R+ Y    P GNV+ +V+  VG A+    +NK    K+DHW+D A+  Y   +I DIK+L
Sbjct: 117 RKKYKKIPPEGNVVLQVTCAVGCAIKNRFRNKDPSVKKDHWMDWAENDYGAKMISDIKAL 176

Query: 260 FRVLVLFIPLPVFWALFDQQGSRWTFQADRMEQDI 294
           F+VL +F+P+PVFW LFDQQGSRWT QA+ M+ D+
Sbjct: 177 FKVLFMFLPMPVFWTLFDQQGSRWTLQAEEMDGDL 211


>SB_21872| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 575

 Score =  143 bits (347), Expect = 3e-34
 Identities = 100/305 (32%), Positives = 152/305 (49%), Gaps = 30/305 (9%)

Query: 13  IVTNEFCERFSYYGMRTILSLYLRDKLGFTDNDATVIYHVFTMFAYFFPVLGAMIADGWL 72
           I+  E CER ++YG+   L  +  D LGF     + +  +F    YF PV G  +AD ++
Sbjct: 49  ILLTELCERLTFYGITANLVPFCEDSLGFKRPMPSTVNLLFQGTCYFIPVFGGWLADTFM 108

Query: 73  GRFRTIFYLSLVYATGSVLISLTAMPP------IGLPQFELT--------ILALLLIAFG 118
           GR+  I+   LVY  G+VL +  A          G     L+        I+AL++IAFG
Sbjct: 109 GRYNVIYGSCLVYFFGTVLFAAGACTTGDILNIFGKQTKYLSSSLRKASSIVALVVIAFG 168

Query: 119 TGGIKPCVSAFGGDQFKLPEQAKYLGYYFSLFYFAINAGSLISTFLTPILRADVHCFGDS 178
           TGGIK  VS FG DQ +  +  + +  +F+ FY+ IN GS +S  L   ++         
Sbjct: 169 TGGIKANVSPFGADQVQ-GKGPRAVQKFFNWFYWFINIGSFLSFTLIVWVQ-------QK 220

Query: 179 DCFSLAFGVPGILMVVSILIFVAGRRLYVIKNPSGNVLGKVSTCVGHAVVK---SIKNKQ 235
             F   + V  I M++  ++F+ GR  YV++ P G+VL      V  A+ +   S KN Q
Sbjct: 221 YTFFYGYAVTAISMMIGTVVFMTGRNWYVVRPPGGSVLTDTYRVVKLAIKRHWSSDKNLQ 280

Query: 236 KRD-HWLDHADEKYDKSL----IEDIKSLFRVLVLFIPLPVFWALFDQQGSRWTFQADRM 290
               HWLD A E Y  +     +E++KSL R+L +F    ++W L+ Q  + +  QA+ M
Sbjct: 281 SEGIHWLDRAKESYGGAFSYHRVENVKSLIRLLPVFAMFIIYWTLYSQMQTSYLIQAEYM 340

Query: 291 EQDIG 295
             D G
Sbjct: 341 MLDYG 345



 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 37/128 (28%), Positives = 68/128 (53%), Gaps = 13/128 (10%)

Query: 518 NSIHILWLIPQYVVMTMGEVMFSVTGLEFSFTQAPASMKSVLQSVWLLTVAFGNLIVVLI 577
           + + I + +PQ++++   EV  S+TGLEF+++QAP  ++ ++  ++L+T   GN +   +
Sbjct: 432 SDMSIFYQVPQFMLIGTSEVFTSITGLEFAYSQAPRCLQGLVMGIFLVTSGLGNYLASAL 491

Query: 578 VE-GNFLDAQW-----------KEFFLFAGLMLLDMFIFTAMAFRYKYVDHKSSTEEDIA 625
                 +D  W             FFL A LM+ +  I+  +A RYKYV  ++  + D+ 
Sbjct: 492 TNIVTSVDKSWYPTDPNTGHLENYFFLLAILMVANFIIYILVAMRYKYVAPQTE-KGDVR 550

Query: 626 VEEIKMPE 633
            +E   PE
Sbjct: 551 TQEKAPPE 558


>SB_1733| Best HMM Match : ATP-synt_C (HMM E-Value=4.5)
          Length = 168

 Score =  110 bits (264), Expect = 4e-24
 Identities = 62/119 (52%), Positives = 78/119 (65%), Gaps = 3/119 (2%)

Query: 526 IPQYVVMTMGEVMFSVTGLEFSFTQAPASMKSVLQSVWLLTVAFGNLIVVLIVEGNFLDA 585
           IPQYVV+T  EVMFSVTGL F+++QAP SMKSVLQS WLLTVAFG+LIVV++     +  
Sbjct: 44  IPQYVVITAAEVMFSVTGLGFAYSQAPNSMKSVLQSFWLLTVAFGDLIVVILSSAKPVKG 103

Query: 586 QWKEFFLFAGLMLLDMFIFTAMAFRYKYVDHKSSTEEDIAVEEIKMPEK--PTIQQKDN 642
             KE FL+ GLM +   IF  M++ Y YV  K   EED   EE  + E     + ++DN
Sbjct: 104 VEKEMFLYGGLMGVICIIFGIMSYFYTYVTPK-DFEEDADEEEKTLGEANGMVLDERDN 161


>SB_56680| Best HMM Match : PTR2 (HMM E-Value=3e-06)
          Length = 606

 Score =  105 bits (251), Expect = 1e-22
 Identities = 86/325 (26%), Positives = 146/325 (44%), Gaps = 32/325 (9%)

Query: 10  VAFIVTNEFCERFSYYGMRTILSLYLRDKLGFTDNDATVIYHVFTMFAYFFPVLGAMIAD 69
           +A ++  E CERF+YYG+     L+L D  G++   A     V+T  A+F   LG ++AD
Sbjct: 58  IACLILAEVCERFAYYGITINFVLFL-DNFGWSMFAAAGGVLVYTSVAWFMCALGGLLAD 116

Query: 70  GWLGRFRTIFYLSLVYATGSVLISLTAM----------PPIGLPQFELTILALLLIAFGT 119
           G  GR  TI    LVY  GSVL+ L A+              +P     +L +L +A G 
Sbjct: 117 GRFGRHSTIISGLLVYYIGSVLLVLLAVWLDYRHKEPSDQDSIPILPWLVLIMLSVAAGE 176

Query: 120 GGIKPCVSAFGGDQFK-LPEQAKYLGYYFSLFYFAINAGSLISTFLTPILRADVH-CFGD 177
           G +K  +SAF  +QF+       + G +  L++F+          +T I + D+   +G 
Sbjct: 177 GAVKSNLSAFSAEQFQGESPSGSWKGIFTCLYWFSNVIALFGLAAVTYIQQTDLSWTYG- 235

Query: 178 SDCFSLAFGVPGILMVVSILIFVAGRRLYVIKNPSGNVLGKVSTCVGHAVVK-------- 229
              ++L FG+P + + ++   F+   + +VI  P G  L  V   +  A  K        
Sbjct: 236 ---YTLGFGIPLVSLTITAAAFLCSSKHFVINRPRGTGLRNVRMIIKQAWSKRNDTVETR 292

Query: 230 ---SIKNKQKRDHWLDHADEKYDKSLIE----DIKSLFRVLVLFIPLPVFWALFDQQGSR 282
              S+   + +  WLD A  +Y  + +     ++KSL +     + L  +W ++ Q  + 
Sbjct: 293 EFTSLHKAKSKMTWLDRASVQYGGTFLNSEVCEVKSLGKAFAFSLCLIPYWMIYSQLYTT 352

Query: 283 WTFQADRMEQDIGSWTLKADQMQVL 307
           +  Q   +  D G   + A  M +L
Sbjct: 353 YILQGLHLHADFGVLVVPAAWMSLL 377



 Score = 48.0 bits (109), Expect = 2e-05
 Identities = 18/53 (33%), Positives = 36/53 (67%)

Query: 521 HILWLIPQYVVMTMGEVMFSVTGLEFSFTQAPASMKSVLQSVWLLTVAFGNLI 573
           +ILW +PQY ++ M EV  S+TGLE  ++  P++ +SV  +++ + +  G+++
Sbjct: 457 NILWQMPQYALLGMSEVFASMTGLEIVYSLCPSTPQSVTSAIYNIMICIGSIL 509


>SB_15813| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 325

 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 28/234 (11%)

Query: 13  IVTNEFCERFSYYGMRTILSLYLRDKLGFT-----------DNDATVIYHVFTMFAYFFP 61
           I+     ER +YYG+ + L ++L  ++ F             N   V    +T  A+F  
Sbjct: 61  IILAVLLERTTYYGILSNLVVFLTTEMDFAFGSLGVGNSTISNGIIVSVFAYTGMAWFMS 120

Query: 62  VLGAMIADGWLGRFRTIFYLSLVYATGS----VLISLTAMPPIGLPQFE-----LTILAL 112
            +G  I D + G +  I+   L+Y  GS    ++  L       L  ++     LTI  L
Sbjct: 121 TVGGFIGDSYSGHYNAIYGSLLIYILGSGSLFMITVLLKYSSSSLNDYKELSVGLTIGTL 180

Query: 113 LLIAFGTGGIKPCVSAFGGDQFKLPEQAKYLGYYFSLFYFAINAGSLISTFLTPILRADV 172
           L+++ G G  K  +SAFG +Q    + +K    +F+ +Y+AIN  S ++  L   ++ + 
Sbjct: 181 LVLSIGEGTYKANISAFGAEQLS-SDDSKTYRQFFNWYYWAINVASFLAYMLLAYIQVN- 238

Query: 173 HCFGDSDCFSLAFGVPGILMVVSILIFVAGRRLYVIKNPSGNVLGKVSTCVGHA 226
             +G    F   + +    ++++ ++F   +  Y IK  SGN+L KV   +  A
Sbjct: 239 --WG----FFYGYLISLCCILLACVLFCIPQSHYNIKPASGNILKKVCGVIREA 286


>SB_25052| Best HMM Match : Prenyltrans (HMM E-Value=6.5)
          Length = 242

 Score = 51.2 bits (117), Expect = 2e-06
 Identities = 24/61 (39%), Positives = 36/61 (59%)

Query: 16  NEFCERFSYYGMRTILSLYLRDKLGFTDNDATVIYHVFTMFAYFFPVLGAMIADGWLGRF 75
           +E    FS +    +L LYL   L F  +    IYH F+M +YF  V+GAM+AD +LG++
Sbjct: 140 HENISAFSGFVFVAVLVLYLTKDLMFNKDKGKAIYHAFSMVSYFTGVIGAMMADSFLGKY 199

Query: 76  R 76
           +
Sbjct: 200 K 200


>SB_14765| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 30

 Score = 50.0 bits (114), Expect = 6e-06
 Identities = 19/28 (67%), Positives = 25/28 (89%)

Query: 252 LIEDIKSLFRVLVLFIPLPVFWALFDQQ 279
           +I DIK+LF+VL +F+P+PVFW LFDQQ
Sbjct: 3   MISDIKALFKVLFMFLPMPVFWTLFDQQ 30


>SB_15812| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 159

 Score = 46.4 bits (105), Expect = 7e-05
 Identities = 20/54 (37%), Positives = 36/54 (66%)

Query: 520 IHILWLIPQYVVMTMGEVMFSVTGLEFSFTQAPASMKSVLQSVWLLTVAFGNLI 573
           + I++ IPQY ++ + EV  SV GLEF++ +AP SM+S +  ++    + G+L+
Sbjct: 34  LSIMYQIPQYGLIGVSEVFASVGGLEFAYREAPPSMQSFVMGLFFFVQSIGSLL 87


>SB_37034| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 56

 Score = 36.3 bits (80), Expect = 0.076
 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 589 EFFLFAGLMLLDMFIFTAMAFRYKYVDHKSSTEEDIAVEE 628
           EFF FAGL+ + M IF  M++ YKY  +  S   D+  E+
Sbjct: 3   EFFFFAGLLAVVMLIFMFMSYYYKYASY--SANGDVKTED 40


>SB_49457| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 941

 Score = 33.9 bits (74), Expect = 0.40
 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 12/111 (10%)

Query: 519 SIHILWLIPQYVVMTMGEVMFSVTGLEFSFTQAPASMKSVLQSVWLLT-VAFGNLIVVLI 577
           S H L L    V M  G++      L     + P  +   + SV +LT V  GNL+V  I
Sbjct: 608 SDHWLQLSTLMVTMVNGQIAML---LRLPVDEVPPEIDREVDSVGVLTLVLMGNLLVAFI 664

Query: 578 VEGNFLDAQWKEFFLFAGLMLLDMFIFTAMAFRYKYVDHKSSTEEDIAVEE 628
             G+ L A W         +L   FI       Y++ D +S+  ED  + E
Sbjct: 665 AAGSLLYAVWP--------LLKKAFISLCRNRGYEFSDRQSNDSEDETLVE 707


>SB_5552| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 28

 Score = 33.5 bits (73), Expect = 0.53
 Identities = 13/26 (50%), Positives = 19/26 (73%)

Query: 199 FVAGRRLYVIKNPSGNVLGKVSTCVG 224
           F+ G++LY IK P+GNVL +V   +G
Sbjct: 3   FIGGKKLYTIKKPAGNVLIQVFKVIG 28


>SB_29473| Best HMM Match : CASP_C (HMM E-Value=6.5)
          Length = 389

 Score = 33.1 bits (72), Expect = 0.71
 Identities = 21/91 (23%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 386 RGEGNCSNIVYNGNFYLKENTANSFFINREGISNFTDNNDKAIN--GVSVRFLSNVQTSV 443
           R +G+ SN+  NGN Y+ E T +   +  + I    + +  A    G+ +  +S+++TS+
Sbjct: 146 RKDGHHSNVDKNGNAYMYEKTRSKIKMKTK-IKRRKERSGNAATDIGMQMDHVSSIETSI 204

Query: 444 TVAIVESKKNKTKLSLQSDDISQVKITKGNG 474
           + A    ++N      +S + +++     NG
Sbjct: 205 SFASYVKRRNPNFYQFRSKEKNKLAAGMENG 235


>SB_16510| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 237

 Score = 30.3 bits (65), Expect = 5.0
 Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 5/84 (5%)

Query: 525 LIPQYVVMTMGEVMFSVTGLEFSFTQAPASMKSVLQSVWLLTVAFGNLIVVLIVEGNFLD 584
           LIP   ++    ++  V GL F+ T  P   +  ++ V+   VA G   V+L+V GN + 
Sbjct: 122 LIPYSEIVLFASII--VGGLFFNGT-TPLMFELAMECVY--PVAEGITAVLLLVAGNVIY 176

Query: 585 AQWKEFFLFAGLMLLDMFIFTAMA 608
             ++  F+F G+ +  M  FT +A
Sbjct: 177 LAFQVAFMFPGVSVKWMNWFTVVA 200


>SB_6822| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 975

 Score = 30.3 bits (65), Expect = 5.0
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 401 YLKENTANSFFINREGISNFTDNNDKAINGVSVRFLSN--VQTSVTVAIVESKKNKTKLS 458
           Y K+    S    +   ++  +   KA+  ++ R LS+  + +S      ES+K+  K  
Sbjct: 567 YAKKARHASPIQGKSKAASLGEEKAKAMLSLAYRRLSSPRIFSSAADEPHESRKDTLKPG 626

Query: 459 LQSDDISQVKITKGNG 474
           L SDDI+  K+  GNG
Sbjct: 627 LDSDDIAVTKVKVGNG 642


>SB_21701| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1906

 Score = 29.5 bits (63), Expect = 8.7
 Identities = 22/89 (24%), Positives = 36/89 (40%)

Query: 344  NFTINTGDFNANNNNIHTIGPLSVYEHLDINADGSIELPYYVRGEGNCSNIVYNGNFYLK 403
            N +IN  + + NNNN   I   S   + + + + +           N +N   N N    
Sbjct: 1780 NSSINNNNSSINNNNSSIINNNSSINNNNSSINNNNSSIINNNSSNNNNNSSINNNNSSI 1839

Query: 404  ENTANSFFINREGISNFTDNNDKAINGVS 432
             N  +S   N   I+N  + N+ +IN  S
Sbjct: 1840 INNNSSIINNNSSINNRNNTNNNSINNRS 1868


>SB_11387| Best HMM Match : MFS_1 (HMM E-Value=4.4e-06)
          Length = 815

 Score = 29.5 bits (63), Expect = 8.7
 Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 2/46 (4%)

Query: 590 FFLFAGLMLLDMFIFTAMAFRYKYVDHKSSTE-EDIAVEEIKMPEK 634
           F++FAG+MLL + +F A+ F + Y D  +  + ++ AV +I +  K
Sbjct: 347 FYIFAGVMLLAL-LFAAVLFEFTYEDDGNDGKVDECAVWKILLQPK 391


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.323    0.140    0.419 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 20,612,643
Number of Sequences: 59808
Number of extensions: 836679
Number of successful extensions: 1968
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1936
Number of HSP's gapped (non-prelim): 24
length of query: 642
length of database: 16,821,457
effective HSP length: 87
effective length of query: 555
effective length of database: 11,618,161
effective search space: 6448079355
effective search space used: 6448079355
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 63 (29.5 bits)

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