BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000468-TA|BGIBMGA000468-PA|IPR000731|Sterol-sensing 5TM box (1118 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7QB81 Cluster: ENSANGP00000011300; n=2; Culicidae|Rep:... 733 0.0 UniRef50_UPI0000D574A3 Cluster: PREDICTED: similar to CG2019-PA;... 729 0.0 UniRef50_UPI00015B49C9 Cluster: PREDICTED: similar to conserved ... 722 0.0 UniRef50_Q9VNJ5 Cluster: CG2019-PA; n=5; Sophophora|Rep: CG2019-... 656 0.0 UniRef50_UPI0000E4717A Cluster: PREDICTED: similar to dispatched... 543 e-152 UniRef50_UPI0000ECBA3F Cluster: dispatched B; n=10; Tetrapoda|Re... 480 e-133 UniRef50_UPI000058420C Cluster: PREDICTED: similar to dispatched... 458 e-127 UniRef50_UPI0000E4A16C Cluster: PREDICTED: similar to dispatched... 450 e-124 UniRef50_UPI0000E4776B Cluster: PREDICTED: similar to dispatched... 438 e-121 UniRef50_Q96F81 Cluster: Protein dispatched homolog 1; n=41; Eut... 436 e-120 UniRef50_Q9C0C1 Cluster: Protein dispatched homolog 2; n=19; Eut... 420 e-115 UniRef50_Q6R5J1 Cluster: Dispatched 2; n=3; Clupeocephala|Rep: D... 415 e-114 UniRef50_Q4SWS4 Cluster: Chromosome undetermined SCAF13541, whol... 406 e-111 UniRef50_UPI0000588F35 Cluster: PREDICTED: similar to dispatched... 405 e-111 UniRef50_UPI0000587C88 Cluster: PREDICTED: similar to dispatched... 391 e-107 UniRef50_A7RVB1 Cluster: Predicted protein; n=1; Nematostella ve... 364 8e-99 UniRef50_Q19153 Cluster: Dispatched family protein 2; n=2; Caeno... 179 3e-43 UniRef50_A7SM68 Cluster: Predicted protein; n=1; Nematostella ve... 157 2e-36 UniRef50_O76372 Cluster: Abnormal chemotaxis protein 14; n=2; Ca... 120 2e-25 UniRef50_A4RS32 Cluster: Predicted protein; n=2; Ostreococcus|Re... 110 2e-22 UniRef50_A4RT66 Cluster: Predicted protein; n=2; Ostreococcus|Re... 101 1e-19 UniRef50_Q010M7 Cluster: Predicted membrane protein; n=3; Eukary... 85 8e-15 UniRef50_A4S176 Cluster: RND family transporter: Dispatched segm... 69 9e-10 UniRef50_A7RP60 Cluster: Predicted protein; n=1; Nematostella ve... 67 3e-09 UniRef50_A7RP59 Cluster: Predicted protein; n=1; Nematostella ve... 67 3e-09 UniRef50_Q013Q5 Cluster: Predicted membrane protein; n=2; Ostreo... 57 2e-06 UniRef50_Q5VTU9 Cluster: Patched domain-containing protein 2; n=... 56 5e-06 UniRef50_UPI00015A7054 Cluster: Patched domain-containing protei... 53 5e-05 UniRef50_A7RNK5 Cluster: Predicted protein; n=1; Nematostella ve... 52 1e-04 UniRef50_A2DYD9 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-04 UniRef50_UPI0000E477D4 Cluster: PREDICTED: hypothetical protein;... 51 2e-04 UniRef50_Q1JXP1 Cluster: Exporters of the RND superfamily-like p... 51 2e-04 UniRef50_Q7RHN1 Cluster: Drosophila melanogaster CG11212 gene pr... 50 4e-04 UniRef50_O15118 Cluster: Niemann-Pick C1 protein precursor; n=39... 50 4e-04 UniRef50_Q7PXL5 Cluster: ENSANGP00000011713; n=2; Culicidae|Rep:... 50 5e-04 UniRef50_Q4UAK5 Cluster: Putative uncharacterized protein; n=1; ... 49 6e-04 UniRef50_UPI00015B5B2F Cluster: PREDICTED: similar to putative h... 49 8e-04 UniRef50_UPI0000DB6CB9 Cluster: PREDICTED: similar to PaTched Re... 48 0.001 UniRef50_A7QPC0 Cluster: Chromosome chr18 scaffold_137, whole ge... 48 0.001 UniRef50_A7SH24 Cluster: Predicted protein; n=5; Nematostella ve... 48 0.001 UniRef50_A7BSE2 Cluster: Integral membrane protein; n=1; Beggiat... 48 0.002 UniRef50_Q6L1D3 Cluster: Transporter involved in lipid transport... 48 0.002 UniRef50_O83769 Cluster: Antibiotic transport protein, putative;... 47 0.003 UniRef50_UPI000038E024 Cluster: hypothetical protein Faci_030014... 47 0.003 UniRef50_Q21L50 Cluster: Patched; n=2; Gammaproteobacteria|Rep: ... 47 0.003 UniRef50_Q1NUP1 Cluster: Exporter, RND superfamily precursor; n=... 47 0.003 UniRef50_Q1K3Y2 Cluster: Patched; n=1; Desulfuromonas acetoxidan... 47 0.003 UniRef50_A2DYE0 Cluster: Putative uncharacterized protein; n=1; ... 46 0.004 UniRef50_UPI00015B5B0C Cluster: PREDICTED: similar to conserved ... 46 0.006 UniRef50_Q5QWJ5 Cluster: Predicted exporter, RND superfamily; n=... 46 0.008 UniRef50_A5APM6 Cluster: Putative uncharacterized protein; n=1; ... 46 0.008 UniRef50_Q5DTE5 Cluster: Putative uncharacterized protein ptr-17... 46 0.008 UniRef50_Q8I266 Cluster: Patched family protein, putative; n=3; ... 45 0.013 UniRef50_O16307 Cluster: Patched related family protein 16; n=2;... 44 0.023 UniRef50_Q17GY7 Cluster: Patched 1, putative; n=11; Endopterygot... 44 0.031 UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.054 UniRef50_UPI0000D573E9 Cluster: PREDICTED: similar to CG5722-PA;... 42 0.071 UniRef50_A7BSN4 Cluster: Exporter of the RND superfamily; n=3; G... 42 0.071 UniRef50_Q23E28 Cluster: Patched family protein; n=1; Tetrahymen... 42 0.071 UniRef50_Q9K6B3 Cluster: Cation efflux system; n=1; Bacillus hal... 42 0.094 UniRef50_Q28P83 Cluster: Exporters of the RND superfamily-like p... 42 0.094 UniRef50_A5K9U0 Cluster: Patched family protein, putative; n=1; ... 42 0.094 UniRef50_Q4RVD6 Cluster: Chromosome 15 SCAF14992, whole genome s... 42 0.12 UniRef50_A6LLS8 Cluster: MMPL domain protein precursor; n=1; The... 41 0.16 UniRef50_Q55BN1 Cluster: NPC1 protein; n=2; Dictyostelium discoi... 41 0.16 UniRef50_Q0AT82 Cluster: Patched family protein precursor; n=2; ... 41 0.22 UniRef50_A3ZT27 Cluster: Probable integral membrane protein; n=1... 41 0.22 UniRef50_A2QWF9 Cluster: Remark: Niemann-Pick C precursor; n=16;... 41 0.22 UniRef50_Q82T82 Cluster: Acriflavin resistance protein; n=6; Pro... 40 0.29 UniRef50_Q1VLX1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.29 UniRef50_A4M778 Cluster: Exporter of the RND superfamily-like pr... 40 0.29 UniRef50_A7RK33 Cluster: Predicted protein; n=2; Nematostella ve... 40 0.29 UniRef50_Q92IG6 Cluster: Putative uncharacterized protein; n=9; ... 40 0.38 UniRef50_Q4RWY5 Cluster: Chromosome 15 SCAF14981, whole genome s... 40 0.50 UniRef50_Q2AD70 Cluster: Putative uncharacterized protein; n=1; ... 40 0.50 UniRef50_Q1VRS2 Cluster: Cation/multidrug efflux pump; n=2; Flav... 40 0.50 UniRef50_A3ZC87 Cluster: Patched family; n=11; Campylobacter|Rep... 40 0.50 UniRef50_Q09614 Cluster: Protein patched homolog 1; n=3; Caenorh... 40 0.50 UniRef50_UPI00015BCDE5 Cluster: UPI00015BCDE5 related cluster; n... 39 0.66 UniRef50_UPI0000DB7411 Cluster: PREDICTED: similar to Niemann-Pi... 39 0.66 UniRef50_Q488G0 Cluster: Putative membrane protein; n=1; Colwell... 39 0.66 UniRef50_Q30QL4 Cluster: Acriflavin resistance protein; n=1; Thi... 39 0.66 UniRef50_Q1PUR2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.66 UniRef50_A0J5C4 Cluster: Exporters of the RND superfamily-like p... 39 0.66 UniRef50_Q13635 Cluster: Protein patched homolog 1; n=79; Verteb... 39 0.66 UniRef50_UPI0000E48D84 Cluster: PREDICTED: similar to Niemann-Pi... 39 0.88 UniRef50_UPI000065FF0C Cluster: Niemann-Pick C1-like protein 1 p... 39 0.88 UniRef50_Q9KM29 Cluster: GGDEF family protein; n=14; Vibrio chol... 39 0.88 UniRef50_A6G9V0 Cluster: Putative rRNA methylase; n=1; Plesiocys... 39 0.88 UniRef50_Q5LRX2 Cluster: Membrane protein, putative; n=1; Silici... 38 1.2 UniRef50_Q9W6T6 Cluster: Patched-2 protein; n=7; Euteleostomi|Re... 38 1.5 UniRef50_Q5RJ13 Cluster: Novel protein; n=9; Euteleostomi|Rep: N... 38 1.5 UniRef50_Q4J8A9 Cluster: Conserved membrane protein; n=2; Sulfol... 38 1.5 UniRef50_UPI0000DA2841 Cluster: PREDICTED: similar to patched1; ... 38 2.0 UniRef50_Q4SP00 Cluster: Chromosome 15 SCAF14542, whole genome s... 38 2.0 UniRef50_Q7M912 Cluster: RND PUMP PROTEIN; n=1; Wolinella succin... 38 2.0 UniRef50_Q2Y8H1 Cluster: Membrane protein, putative; n=1; Nitros... 38 2.0 UniRef50_Q1Q069 Cluster: Putative uncharacterized protein; n=1; ... 38 2.0 UniRef50_A7HL36 Cluster: Putative uncharacterized protein; n=1; ... 38 2.0 UniRef50_A4BDC7 Cluster: Predicted exporter of the RND superfami... 38 2.0 UniRef50_Q09540 Cluster: Patched family protein 2; n=1; Caenorha... 38 2.0 UniRef50_Q6ZU28 Cluster: Patched domain-containing protein 3; n=... 38 2.0 UniRef50_Q6ZSJ0 Cluster: CDNA FLJ45488 fis, clone BRTHA2003759; ... 38 2.0 UniRef50_Q979Z5 Cluster: Membrane protein; n=2; Thermoplasma|Rep... 38 2.0 UniRef50_Q4T749 Cluster: Chromosome undetermined SCAF8317, whole... 37 2.7 UniRef50_A6LM56 Cluster: Exporter of the RND superfamily-like pr... 37 2.7 UniRef50_A1AXL6 Cluster: Putative integral membrane protein; n=2... 37 2.7 UniRef50_Q9SVF0 Cluster: Putative uncharacterized protein F22I13... 37 2.7 UniRef50_Q9XWL9 Cluster: Putative uncharacterized protein ptr-18... 37 2.7 UniRef50_Q18129 Cluster: Patched related family protein 1; n=2; ... 37 2.7 UniRef50_O29790 Cluster: Putative uncharacterized protein; n=1; ... 37 2.7 UniRef50_Q9Y6C5 Cluster: Protein patched homolog 2; n=14; Theria... 37 2.7 UniRef50_Q19127 Cluster: Niemann-Pick C1 protein homolog 1 precu... 37 2.7 UniRef50_UPI00003650C0 Cluster: patched domain containing 3; n=1... 37 3.5 UniRef50_Q5QJP1 Cluster: Putative uncharacterized protein; n=2; ... 37 3.5 UniRef50_A5FXC8 Cluster: Exporter of the RND superfamily-like pr... 37 3.5 UniRef50_A4J5Y7 Cluster: Phosphatidate cytidylyltransferase; n=1... 37 3.5 UniRef50_A3HZ07 Cluster: AmpG protein, beta-lactamase induction ... 37 3.5 UniRef50_A3HX91 Cluster: Putative ABC transport system, membrane... 37 3.5 UniRef50_A0RMA9 Cluster: Hydrogenase 4 membrane subunit; n=1; Ca... 37 3.5 UniRef50_Q01KH5 Cluster: H0409D10.4 protein; n=5; Eukaryota|Rep:... 37 3.5 UniRef50_UPI000038DBBD Cluster: COG0841: Cation/multidrug efflux... 36 4.7 UniRef50_Q4FPX8 Cluster: RND superfamily multidrug efflux pump; ... 36 4.7 UniRef50_Q03SC1 Cluster: Predicted membrane protein; n=1; Lactob... 36 4.7 UniRef50_A6LJJ4 Cluster: Exporter of the RND superfamily-like pr... 36 4.7 UniRef50_Q9XXR9 Cluster: Putative uncharacterized protein ptr-19... 36 4.7 UniRef50_Q4DFK7 Cluster: Putative uncharacterized protein; n=2; ... 36 4.7 UniRef50_A0A5F1 Cluster: Patched family protein,; n=1; Toxoplasm... 36 4.7 UniRef50_Q4J7L8 Cluster: Putative uncharacterized protein; n=1; ... 36 4.7 UniRef50_UPI00006CFF77 Cluster: Ferric reductase like transmembr... 36 6.2 UniRef50_UPI0000498B66 Cluster: hypothetical protein 145.t00006;... 36 6.2 UniRef50_Q8EFP7 Cluster: AcrB/AcrD/AcrF family protein; n=21; Al... 36 6.2 UniRef50_Q73QH4 Cluster: Membrane protein, putative; n=1; Trepon... 36 6.2 UniRef50_O32182 Cluster: YusP protein; n=13; Bacillus|Rep: YusP ... 36 6.2 UniRef50_Q3D1W5 Cluster: Regulatory protein, putative, truncatio... 36 6.2 UniRef50_Q0R4F8 Cluster: Transporter-like protein; n=3; Pseudomo... 36 6.2 UniRef50_Q6AW16 Cluster: Patched family protein 3, isoform b; n=... 36 6.2 UniRef50_Q26592 Cluster: ORF 3 precursor; n=1; Schistosoma manso... 36 6.2 UniRef50_A7RFX5 Cluster: Predicted protein; n=1; Nematostella ve... 36 6.2 UniRef50_A5K0C5 Cluster: Dynein heavy chain, putative; n=2; Plas... 36 6.2 UniRef50_UPI0000586B35 Cluster: PREDICTED: similar to Niemann-Pi... 36 8.2 UniRef50_Q0ARW7 Cluster: Exporter of the RND superfamily; n=2; P... 36 8.2 UniRef50_A6LJ70 Cluster: Major facilitator superfamily MFS_1; n=... 36 8.2 UniRef50_A3D7T1 Cluster: Putative uncharacterized protein; n=1; ... 36 8.2 UniRef50_Q6CBA1 Cluster: Similar to tr|Q12200 Saccharomyces cere... 36 8.2 >UniRef50_Q7QB81 Cluster: ENSANGP00000011300; n=2; Culicidae|Rep: ENSANGP00000011300 - Anopheles gambiae str. PEST Length = 1155 Score = 733 bits (1811), Expect = 0.0 Identities = 378/918 (41%), Positives = 559/918 (60%), Gaps = 37/918 (4%) Query: 144 WGFGINVTN-EDEHAVLLKDHSRKQWLSLKNMQRIADKPINLNYASGT--CGPPISDYAH 200 W +G N + +E + R +W +L+ ++ +PI + S C P +YAH Sbjct: 179 WEYGRNQSYYTEEVGNKTMEKKRAKWDTLRRLKP-PPEPIETHIPSDGFFCESPNKEYAH 237 Query: 201 LVITNTD---NSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICCPVWSLPN 257 LV+ + N SL LC+ + CQR SE+ CC WS+ N Sbjct: 238 LVVQRINHNLNDSLFELNAFLALCELEQRIFRVDHYGDI--CQRELTSEE-CCRPWSIVN 294 Query: 258 YIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACDLDHCNVPKYCTQHNAVY 317 Y+ +S K SC LN+EDV T+L C Y+ L C C P C QHNAVY Sbjct: 295 YVTFLSNKTSCFELNEEDVAMVKTLLYDCFSYYQTMKLSNDCTQSSCFAPSECKQHNAVY 354 Query: 318 NLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVLPYYKKLENSNMSYDNLVIPAID 377 N+L YL + + F N + +F+ TM+FLP+ RS + +Y L N++ D + + A+D Sbjct: 355 NILHYLANVD-FIRQNESAEFLNATMIFLPIARSIKSMEFYHSLSKVNLANDLVSVVAMD 413 Query: 378 FGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVY 437 GLKNALFD ++ D WL+ LGGIFV C+W+YT SL +TL A+ FSLGIAYF Y + Sbjct: 414 MGLKNALFDECLLRDGWLLGLGGIFVVLCMWLYTGSLFVTLMTVTAVAFSLGIAYFIYSF 473 Query: 438 VFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDN---VVYQENGVLDINI 494 +F L FFPFMNLL +++V+GIGADDAFI++KIW+ + +K V+ N Sbjct: 474 IFELTFFPFMNLLAVIVVVGIGADDAFIFLKIWQCTIAERLKCGGGIVIPIAPSTASCNS 533 Query: 495 SSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNF 554 + +T LV+I+ T+RH+ +++ +T+LTTA AFYASYVS I A+ CF +F+GTAV+ N+ Sbjct: 534 EAKSDT-LVEIMGSTLRHAALSMLVTSLTTAAAFYASYVSSITAVRCFGIFSGTAVMANY 592 Query: 555 VLMMTWLPISVFIVD-VKLYAKKKTFLDLVHKNVNEMWENIRIVLNRF--TII-CVTKFH 610 LM+TWLP +V I + + K F + H+ + +I + R TII + Sbjct: 593 FLMVTWLPAAVSIAERLSCLMLLKPFGRVTHR-CTIPFISIAQLSRRVEETIIDLIVNLP 651 Query: 611 IAFVVVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFEQYEMQYRDKFLFERLSKD 670 +V ++G +G +S V+V + P L LPDS F+LF ++HPFE+Y+ +YRD F FE++ Sbjct: 652 WLWVTLLGTIGIMSGVLVLHWPKLRLPDSPDFKLFISNHPFERYDSEYRDMFWFEKMYSA 711 Query: 671 LGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSWLLGFCARIKGQP 730 + K+PLR+VWGV+ +D G+ +DP +G L FDE+F++S P+SQ WLL FC RIK Q Sbjct: 712 TES-FKIPLRFVWGVQPVDRGDLLDPEQRGALYFDESFNMSAPESQQWLLQFCRRIKNQT 770 Query: 731 FYQQTLGPLLPNCFIESFKMYMSRRCIDNIDKINRSPCCETSKFPYKKEVFDFCIIKAME 790 FY ++ G L+PNCFIE+F +M RRC D + +I+R+PCCE S FP+ ++FD C+ +++ Sbjct: 771 FYSESKGLLVPNCFIENFIEWMRRRCNDTMGEIDRTPCCEVSPFPFTPDIFDQCLPESIL 830 Query: 791 SLYQTPRELFMPGVAGPKFLRSA-------------KP--PIIAALVVEFESIVPYSLSY 835 SLY+TPR+ F+PGVAGPKF RS+ KP ++ A+V+EFES +++SY Sbjct: 831 SLYETPRQFFVPGVAGPKFARSSFLVAGEPLERISPKPNDTVVKAVVIEFESTQIFTMSY 890 Query: 836 SEMNKFFTEVEKWTQTELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFI 895 +E++ F VE+W +L +AP M WF S+ +F+DLQ TL++GT+VA+ ++ + + Sbjct: 891 TEIDAFVRTVERWLAEQLRDAPPTMANAWFTSELEFFDLQDTLSTGTMVAIAMAMGVALL 950 Query: 896 VLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYA 955 VL+ TLN + S+ A+ + + T+AVLV+ WKLN+LESVA+ST+ GLAVDFSLHY Sbjct: 951 VLMLVTLNVLISLYAIVTVTLTILSTVAVLVLLGWKLNVLESVAVSTAIGLAVDFSLHYG 1010 Query: 956 LSY-TNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMT 1014 + Y + ++ + ++ G AG +L S++L Y QIG FLV++M+ Sbjct: 1011 VHYRLSTEPDRRSSTRFSLQRMLGPTAMAAITTGIAGALMLPSSVLAYIQIGVFLVIVMS 1070 Query: 1015 VSWTYATFFLCSLLHIVG 1032 +SW YATFFL SLL ++G Sbjct: 1071 ISWLYATFFLMSLLRLIG 1088 Score = 78.2 bits (184), Expect = 1e-12 Identities = 35/77 (45%), Positives = 47/77 (61%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWENL 64 Y + + R +LVL V I S+ V+ L +LP F DP +GFE RGT++ R+ AW NL Sbjct: 11 YYKLLARRPHLVLVAVGIFSVACIVVALCTRKLPDFDDPTLGFEARGTSIGKRWTAWRNL 70 Query: 65 NDETRPSKRLAVNPKEI 81 +ET S RL NPKE+ Sbjct: 71 LEETSLSGRLVANPKEL 87 >UniRef50_UPI0000D574A3 Cluster: PREDICTED: similar to CG2019-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG2019-PA - Tribolium castaneum Length = 1077 Score = 729 bits (1803), Expect = 0.0 Identities = 368/903 (40%), Positives = 541/903 (59%), Gaps = 59/903 (6%) Query: 163 HSRKQWLSLKNM------QRIADKPINLNYASGTCGPPISDYAHLVITNTDNSSLLSYKN 216 + W +L+NM + +A KP+ ++ CG P +AH+V+ + + L + K+ Sbjct: 104 YENNNWRALQNMLHPKAAENVAVKPVEID--GFFCGYPDERFAHIVLKSKNAEDLFTLKS 161 Query: 217 VERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICCPVWSLPNYIALISGKDSCVNLNKEDV 276 + LC+ + + H + CC WSL NYIA++ + SC+ + +EDV Sbjct: 162 LLALCRIEHEFIEAHYYKDLCISNQDYHVKK-CCKPWSLANYIAILHNRTSCLAITEEDV 220 Query: 277 KKAVTILKKCAGYFHNFTLMAAC-DLDHCNVPKYCTQHNAVYNLLFYLIDSEAFSPLNNA 335 T+L C+ YFH LM C D +C+VP C +H+AV+N+L +L S F P N Sbjct: 221 NATKTLLINCSQYFHKLQLMQDCFDKGYCDVPLECVRHDAVFNVLNFLT-STTFLPPNVH 279 Query: 336 QKFVKNTMLFLPLPRSDTVLPYYKKLENSNMSYDNLVIPAIDFGLKNALFDIWIIEDTWL 395 ++ TM+FLPL S +LPYY ++ ++ Y+ + + A++FG+K+ALFD ++ D WL Sbjct: 280 HHRLQETMIFLPLACSTAILPYYHEIIQMDLEYEGISVVAMEFGIKDALFDECLLRDAWL 339 Query: 396 IALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIV 455 + G +FV C+W+YT SL LT+ AI FSLGI+YF Y+ VF L FFPFMNLL I++ Sbjct: 340 MTSGALFVLLCMWLYTESLFLTIMTIIAIIFSLGISYFMYMLVFELKFFPFMNLLAIIVA 399 Query: 456 LGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIV 515 +GIGADDAFI+ KIW + ++ + +V+++ +T H+ Sbjct: 400 IGIGADDAFIFCKIWHKVKEEK---------------------NSSIVKLMGDTFYHAFF 438 Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAK 575 ++F+T+LTT+VAF ASY S + AI CFS+F+GTAV+ NF +M+TW P V I + + Sbjct: 439 SMFVTSLTTSVAFLASYASSVTAICCFSIFSGTAVITNFFMMITWFPACVVIWERSCCSN 498 Query: 576 ----KKTFLDLVHK-----------NVNEMWENIRIV------LNRFTIICVTKFHIAFV 614 K + + + N++ W + RF + V F ++ Sbjct: 499 VDLAKSCLMACLQRWCCSKLIKPTWNLSTTWPKCSFLGRIWSSKERFLLDSVVNFRYIWL 558 Query: 615 VVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFEQYEMQYRDKFLFERLSKDL-GT 673 V++ +G IS +VV Y P LPDS +FQLF +SHPFEQY+ +Y+ F F R ++L G Sbjct: 559 VILSIIGLISTIVVIYYPKFQLPDSSEFQLFDSSHPFEQYDFKYKYHFWFRREERNLVGV 618 Query: 674 GTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQ 733 K+PLR+VWGV +DNG+H++P S G L D +F IS P+SQ WLL FC R++ QPF+Q Sbjct: 619 NYKLPLRFVWGVLPVDNGDHLNPESYGKLELDPDFDISQPESQVWLLKFCKRLQRQPFFQ 678 Query: 734 QTLGPLLPNCFIESFKMYMSRRCIDNIDKINRSPCCETSKFPYKKEVFDFCIIKAMESLY 793 T GPLLPNCFIE+F M R C+D+ + + SPCC+ S FPY VF CI++ M +Y Sbjct: 679 PTFGPLLPNCFIETFMRSMQRDCVDSFSQRDWSPCCKMSTFPYNSSVFYECIVEEMTDIY 738 Query: 794 QTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTEL 853 +TP + +PG+AGPKF + + P I A++VE++S YS+SY M++F+T+VE W EL Sbjct: 739 ETPSQYLIPGMAGPKFSKD-QFPTIKAVIVEYDSNYSYSMSYEYMHEFYTKVENWMIEEL 797 Query: 854 ENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTA 913 + AP MK GWF+S+ +FYDLQR L+ TI+A+++S L IVL+ +TLN +TS+ A+ Sbjct: 798 KTAPKTMKNGWFISELEFYDLQRELSENTILAIIVSMGLALIVLLLSTLNILTSLYAILT 857 Query: 914 MIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSY----TNASGNKSARV 969 + S VT+AVLV+ WKLNILES+ +ST+ GL VDFSLHY ++Y + + A Sbjct: 858 ITCSIFVTVAVLVLLGWKLNILESITVSTAIGLTVDFSLHYTVNYRLCPLALADERIAAT 917 Query: 970 KYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLH 1029 KY G AG F++ S +LPY QIG FLV +M+VSW YATF L ++L Sbjct: 918 KYALSYMAGPVLMAALTTGAAGAFMMPSLILPYIQIGIFLVTVMSVSWIYATFHLGAMLA 977 Query: 1030 IVG 1032 I+G Sbjct: 978 IIG 980 Score = 79.0 bits (186), Expect = 7e-13 Identities = 35/79 (44%), Positives = 52/79 (65%), Gaps = 2/79 (2%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELP--SFSDPIVGFETRGTTLAHRFIAWE 62 ++ IV H Y+++ V++ S VIP L P FSDP +GF TRGT +++R AW+ Sbjct: 6 FAHIIVHHPYIIISAVAVFSGTCLVIPFTLKTKPFKDFSDPKMGFTTRGTAISNRLTAWK 65 Query: 63 NLNDETRPSKRLAVNPKEI 81 NL++ TRPS + A+NPK+I Sbjct: 66 NLDESTRPSGQFAINPKDI 84 >UniRef50_UPI00015B49C9 Cluster: PREDICTED: similar to conserved hypothetical protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to conserved hypothetical protein - Nasonia vitripennis Length = 1139 Score = 722 bits (1785), Expect = 0.0 Identities = 420/1139 (36%), Positives = 624/1139 (54%), Gaps = 74/1139 (6%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWENL 64 YSR + H + +L V + S ++PL + P FSDP +GFE RGT LA R AW+NL Sbjct: 6 YSRVLAHHPFAILIAVFVFSSTCLIVPLTTKKFPDFSDPQLGFEARGTPLAQRLTAWKNL 65 Query: 65 NDETRPSKRLAVNPKE----IEDQIRMNRTYYNKTHQXXXXXXXXXXXXXXXXXXXXMVP 120 + + P L NP E I+D R N+ +K +Q Sbjct: 66 LESSNPRGDLVDNPLEYYYYIQDINRQNKEKLSKVNQSSSTKKKARKNHGKNKKYNDKTK 125 Query: 121 NITGLEKTWSDYSELNISDGHVHWGFGINVTNEDEHAVLLKDHSRKQWLSLKNMQRIADK 180 T ++K D E N W + + +D H++ K+++ ++ + ++ Sbjct: 126 --TAIDKD-DDKEEKNT------WEELMKLKAKDRHSIGDKNNNHSGDEENEDKEEFYEQ 176 Query: 181 PINLNY-ASGT-CGPPISDYAHLVITNTD-NSSLLSYKNVERLCKFQSXXXXXXXXXXXX 237 + + A G C P S Y+ +VI++ D +L S + V C + Sbjct: 177 EGHFDGDADGFFCNLPSSAYSRVVISSKDPEQNLWSLEGVLAQCHIDAALRASPHFPSL- 235 Query: 238 XCQRTTHSEDICCPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMA 297 CQR + CC WS NY+AL+S + SC+ + ++D+ K +IL+KC+ ++ N L Sbjct: 236 -CQRQLDRKQKCCRSWSPANYVALLSNRTSCLAVTEQDLLKVESILQKCSYFYRNLELTP 294 Query: 298 AC-DLDHCN--VPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKF-VKNTMLFLPLPRSDT 353 C + C VP C +NA Y+L+ YL+D E NN +++ M+ LP+ S Sbjct: 295 DCAENTRCQRRVPSVCYNYNAAYHLIHYLLDIEFLVTSNNTTNMQLRSAMIILPIAASSA 354 Query: 354 VLPYYKKLENSNMSYDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRS 413 L +YK + ++N+SY L + A+ GLK+ LFD +I D++L+ LG FV C+W YT S Sbjct: 355 TLDFYKDISSNNLSYKKLHVSAMQLGLKSTLFDKLLISDSFLVLLGFGFVTICIWSYTGS 414 Query: 414 LILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMI 473 LI+T+ + FSLGI+Y FY + ++ FPFMNLL +V+ GIG+DDAFI+ KIW+ Sbjct: 415 LIITVSTILVVIFSLGISYAFYTIILKINHFPFMNLLAVVVATGIGSDDAFIFCKIWECN 474 Query: 474 GKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYV 533 +Q +N NG L +++ ETM+H+ ++F+TTLTTAVAF+AS V Sbjct: 475 KRQKSLNN----NNG-------------LTRLVHETMKHAAPSMFVTTLTTAVAFFASIV 517 Query: 534 SYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVD---VKLYAKKKTFLDLVHKNVNEM 590 S + AINCFS+F+G V+ NF+LM+TWLP SV I + + + + + + + Sbjct: 518 SNVTAINCFSLFSGITVIANFLLMVTWLPASVIIAERCGTNIISPANFIIRKIIRPLKLF 577 Query: 591 WENIRIVLNRFTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHP 650 ++ + F + V + ++ +LG S VVF PGL LPDS FQLF +SH Sbjct: 578 FDKVAHSFADFLVKLVISLKWIWFILFLSLGIGSCFVVFRFPGLQLPDSPDFQLFDSSHL 637 Query: 651 FEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSI 710 FEQY++ Y +F FE++ + G G +P+R+VWGV +DNGN+++P S+G L D+ F + Sbjct: 638 FEQYDLIYSKRFWFEKIEQGDG-GDVLPMRFVWGVMPVDNGNYLNPESRGTLEVDDTFDV 696 Query: 711 SDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNID-KINRSPCC 769 + +SQ WL FC ++ Q FY+ TLGPLLPNCFIES + +M RRC D ID KI+RSPCC Sbjct: 697 TTRESQVWLQNFCKNLRLQTFYRSTLGPLLPNCFIESLQPWMERRCEDPIDPKIDRSPCC 756 Query: 770 ETSKFPYKKEVFDFCIIKAMESLYQTPRELF---MPGV--AGPKF-----------LRSA 813 E + FPY +V C +A+ +++TP L+ G+ AG KF + + Sbjct: 757 ERNTFPYDPKVLKHCAAEAIAEIHRTPSHLWNFRSQGIQTAGLKFRKENYTNVDSSINNN 816 Query: 814 KP---------PIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGW 864 K P I A++VE++S +SLS++EM+KF+ EVE W Q +L +AP GMK GW Sbjct: 817 KSNIIQLTKVIPEIQAVIVEYDSNFAFSLSFAEMDKFYNEVENWMQNQLLSAPPGMKNGW 876 Query: 865 FLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAV 924 F+S +FY+LQRTL GTI A+++S L VL TLN S+ A+ A+ + T+T+AV Sbjct: 877 FVSYLEFYELQRTLYDGTIWAIVVSMGLALTVLALVTLNPFVSLYAILAVGSAITITVAV 936 Query: 925 LVINNWKLNILESVAISTSAGLAVDFSLHYALSY-TNASGNKSARVKYXXXXXXXXXXXX 983 L++ WKLN+LESVA++T+ GLA DFSLHY +SY + + ++ RVK Sbjct: 937 LILLEWKLNVLESVAVTTAIGLATDFSLHYGVSYRASTAEHRLERVKMALEQMGGPTLMA 996 Query: 984 XXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRS---SIKESP 1040 G AG +L S +L Y QIG FLV+IM VSW YATFFLC +L I G S + P Sbjct: 997 ALTTGAAGALMLPSGVLAYIQIGLFLVIIMGVSWIYATFFLCPMLAIAGPSYHFAQFRYP 1056 Query: 1041 SRERKPVSRVNSVSSGVPNLESHELEHLADSNRTNVTHSQSPSSVSATTVVLHDDYKTP 1099 +R S ++ +ESH+ + + S+S S S+T H D P Sbjct: 1057 KIQRSLFSLNRRIADNPHEIESHQSINKKRKKPKGMV-SESTLSNSSTVCQFHCDSSLP 1114 >UniRef50_Q9VNJ5 Cluster: CG2019-PA; n=5; Sophophora|Rep: CG2019-PA - Drosophila melanogaster (Fruit fly) Length = 1218 Score = 656 bits (1622), Expect = 0.0 Identities = 356/934 (38%), Positives = 537/934 (57%), Gaps = 60/934 (6%) Query: 146 FGINVTNEDEHAVLLKDHSRKQ-WLSLKNMQRI-----ADKPINLNYASGTC-GPPISDY 198 +G N T+ DE + ++K W LK + AD C P +Y Sbjct: 194 YGHNTTSVDEEEHQQRVQTKKSTWRLLKQAATLPTDGWADMHRRQPIEGFFCDSSPRKEY 253 Query: 199 AHLVITNTD---NSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICCPVWSL 255 +H V+ SL + +C+ Q + T CC WSL Sbjct: 254 SHFVVQRIGPNATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTE---CCRPWSL 310 Query: 256 PNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAAC-DLDHCNVPKYCTQHN 314 PNY A+++ K SC +L EDV T+L C YFH+ + C ++ HC P+ C + N Sbjct: 311 PNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEYFHDLKMDNHCNEIPHCRAPEECKRLN 370 Query: 315 AVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVLPYYKKLENSNMSYDNLVIP 374 V+N+L +L D +F N++ ++K M+F+P+ +S+ +LP + + E+ + + + + Sbjct: 371 IVFNVLNFLTDF-SFIKSNDSNVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVV 429 Query: 375 AIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFF 434 A+D GL+N LF+ ++ D WL++LGG FV A VW+YT S +TL AI FSLG+AYFF Sbjct: 430 AMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFF 489 Query: 435 YVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKD--NVVYQENGVLDI 492 Y V FFP+MNLL +V+++GIGADD F+++KIW + + + + Q L Sbjct: 490 YAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTERFSNRCTLTTQSQSALPT 549 Query: 493 NISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLV 552 +S L I+ TMRH+ ++F+T+LTTA AFYASY S I AI CF +FAGT V+ Sbjct: 550 LENSDHTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVT 609 Query: 553 NFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVNEMWENIRIVLNRFTII---CVTK- 608 N++LM+TWLP SV I++ +L+A T + H ++ + +NRF + C+TK Sbjct: 610 NYLLMITWLPASVSIME-RLFA---TRMSCHHPMSIKLIHACKKSINRFCQMFEECITKS 665 Query: 609 ---FHIAFVVVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFEQYEMQYRDKFLFE 665 + ++++ GALG S V+VF+ PGL LP+ FQLF + HPFE Y + +F FE Sbjct: 666 IMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYS-SLKQQFWFE 724 Query: 666 RLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSWLLGFCAR 725 + KM + +VWGV+A+D+G++ +P S GHL +D NF++S +Q W+L FC Sbjct: 725 K-PLQAYENFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQS 783 Query: 726 IKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNID--KINRSPCCETSKFPYKKEVFDF 783 ++ QPFY++TLG LLPNCFIE+ YM RRCID++D + +RSPCC+ ++FP++ +F++ Sbjct: 784 VRQQPFYKETLGMLLPNCFIENLIDYMKRRCIDDMDSTRKDRSPCCD-AQFPFEPHIFEY 842 Query: 784 CIIKAMESLYQTPRELFMPGVAGPKFLRSAK------------------------PPIIA 819 C+ +++ ++Y T F PGVAGPKF + + P ++ Sbjct: 843 CLPQSISNMYDT--TFFRPGVAGPKFAEAPRLETEDYLGMSGNESAEYSTNGSFTPLLVK 900 Query: 820 ALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSDFQFYDLQRTLA 879 ALV+EFES V YS Y+ + +F+ VE W Q +L+ AP ++ GWF SD +FY++Q TL+ Sbjct: 901 ALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLS 960 Query: 880 SGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVA 939 T VA+ L+ A VL+ T+N + S+ A+ + S T+AVL++ W+LNILES+A Sbjct: 961 HDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIA 1020 Query: 940 ISTSAGLAVDFSLHYALSY-TNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSN 998 +ST+ GLAVDFSLHY + Y + + A ++ G AG ++ SN Sbjct: 1021 VSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASN 1080 Query: 999 LLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 +LPY QIG FLV++M VSW YATFFL SLL + G Sbjct: 1081 ILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAG 1114 Score = 74.5 bits (175), Expect = 1e-11 Identities = 32/87 (36%), Positives = 52/87 (59%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWENL 64 Y + R YLV+ ++++ + ++ L+L++LP FSDP +GFETRGT + R AW NL Sbjct: 12 YYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNL 71 Query: 65 NDETRPSKRLAVNPKEIEDQIRMNRTY 91 ET L NP ++ ++ R+ + Y Sbjct: 72 LQETDHHGALFSNPSDLWERRRVEQGY 98 >UniRef50_UPI0000E4717A Cluster: PREDICTED: similar to dispatched 1; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dispatched 1 - Strongylocentrotus purpuratus Length = 1428 Score = 543 bits (1340), Expect = e-152 Identities = 298/870 (34%), Positives = 482/870 (55%), Gaps = 53/870 (6%) Query: 191 CGPPISDYAHLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICC 250 CG P YA +V +L + + + +C+ + C T++ + CC Sbjct: 398 CGTPKKLYARMVFEPLQGENLFNAEALHSMCRLE-LQTIRSHVQFMKACY-TSNVTNACC 455 Query: 251 PVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACD------LDHC 304 P WSLPNY+AL++ K +C N+ DV+ + +L+ C+ ++ L C + C Sbjct: 456 PSWSLPNYVALLNNKSNCFNITNADVRATLQLLRTCSHFYRTRELRHDCSHGGASLSNSC 515 Query: 305 -NVPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVLPYYK-KLE 362 NVP CT+ +AVY++L YL+D + + V + LP+ + V Y + + Sbjct: 516 ANVPGKCTRFDAVYHILHYLVDVDFMCVERPNNERVTYALSVLPVYAGNDVRAIYDDEFK 575 Query: 363 NSNMSYDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFA 422 ++ I + FG+K LF ++ D LG +FV +W+Y SL +T+ Sbjct: 576 AGDVRDQTTKISGLYFGIKQDLFSEYLTTDAIYPCLGVVFVVLLMWMYIGSLFVTVMTVL 635 Query: 423 AITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNV 482 ++ SL AYF Y VF + FFPFMNL +++++GIGADDAF++ IW KQ KD Sbjct: 636 SMGMSLICAYFVYFAVFRIPFFPFMNLTSVILLVGIGADDAFVFCDIW----KQSRKDR- 690 Query: 483 VYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCF 542 +A I+V ET+RH+ +++F+T+LTTA AFYA+ +S I AI CF Sbjct: 691 ------------PNAPRVIVVM---ETLRHAALSMFVTSLTTASAFYANTISNITAIKCF 735 Query: 543 SVFAGTAVLVNFVLMMTWLPISVFIVDV--------------KLYAKKKTFLDL---VHK 585 ++AGTA+L++FVL +TWLP +V I D+ K + +K+F + +++ Sbjct: 736 GLYAGTAILLHFVLSITWLPAAVVIEDIYFKDLTDCSSQKHEKKFKTQKSFFNHLVDIYR 795 Query: 586 NVNEMWEN-IRIVLNRFTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLPDSKQFQL 644 E + + R+ + V K + +++++G + ++F P L LP +FQL Sbjct: 796 RCTEWFSDWARVFFQKILPCVVIKPRLLWLLLLGIVMLGGFCLIFLDPRLQLPTLPEFQL 855 Query: 645 FQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVF 704 F++ HPFE+Y+ ++D F FE++++ +P+ VWGV+ ID+GN +DP G+LV Sbjct: 856 FRSMHPFERYDFVFKDLFWFEKVNRG-SLYAHLPITVVWGVEPIDSGNPLDPDDIGNLVL 914 Query: 705 DENFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYM-SRRCIDNIDKI 763 + +F ++ PKSQ WLL FC ++ Q F+ T + NCFIE+F +M SR CID + Sbjct: 915 NPDFDMASPKSQLWLLRFCKLLRNQTFFSSTPSLKIENCFIETFSEWMDSRSCIDVGTGM 974 Query: 764 NRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVV 823 N +PCC+ S+FPY + VF+ C+ A+ L+Q F GP+F ++ + A+++ Sbjct: 975 NNAPCCKGSRFPYSRSVFNQCLQTAVTELHQFSPSYFDKWKPGPRF--GSQDNAVKAVII 1032 Query: 824 EFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSDFQFYDLQRTLASGTI 883 EF+S +S SY EM +F+T++E W + L+ AP G+ GWF+S FY+LQ LA GT Sbjct: 1033 EFDSSYAFSHSYEEMKEFWTKLESWMKPVLKTAPPGLGEGWFISYLDFYNLQDNLARGTP 1092 Query: 884 VALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTS 943 ++L LS + +V+ T NFV S+ A+ ++ + VTI LV+ W+LNILESV +S S Sbjct: 1093 LSLGLSIIIAMVVMFLTTQNFVISLFAILSISGTICVTIGALVLLGWQLNILESVILSVS 1152 Query: 944 AGLAVDFSLHYALSYTNA-SGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPY 1002 GL++DF++HY ++Y A ++ +RV Y AG ++ +++L Y Sbjct: 1153 VGLSIDFTVHYGVAYRIAPEPDRESRVVYSLAHMGSAISMAALTTFVAGALMMPASILSY 1212 Query: 1003 SQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 +Q+G FL+LIM +SW Y+T F SL ++G Sbjct: 1213 TQMGTFLMLIMIISWLYSTLFFQSLCRVIG 1242 Score = 65.3 bits (152), Expect = 9e-09 Identities = 28/77 (36%), Positives = 46/77 (59%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWENL 64 Y+ + R+S +V+ + + TV+ + E P FSDPI GFE RGTT++ R IAW N+ Sbjct: 244 YAMLLNRYSIIVILLIVAVVTACTVVAALFFETPDFSDPIAGFEPRGTTISERSIAWSNM 303 Query: 65 NDETRPSKRLAVNPKEI 81 ++T L+ +P ++ Sbjct: 304 MNQTGAGLPLSTHPVKL 320 >UniRef50_UPI0000ECBA3F Cluster: dispatched B; n=10; Tetrapoda|Rep: dispatched B - Gallus gallus Length = 870 Score = 480 bits (1183), Expect = e-133 Identities = 291/876 (33%), Positives = 457/876 (52%), Gaps = 68/876 (7%) Query: 191 CGPPISDYAHLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICC 250 CGPP Y+ LV +T SL + + ++ +C+ + CQRT +E CC Sbjct: 15 CGPPEKGYSQLVFMSTTAGSLWNLQAIQSMCQIEQDKIRSHVHFRDL-CQRTEANE--CC 71 Query: 251 PVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAAC--------DLD 302 P WSL NYIA++ + SC+ + + D+ + +L+ CA +H L +C Sbjct: 72 PSWSLGNYIAVLYNRSSCLEITQGDISHTLALLRACAPDYHKGILTPSCIGPETMRQKHS 131 Query: 303 HC-NVPKYCTQHNAVYNLLFYLIDSEAFSP--LNNAQKFVKNTMLFLPLPRSDTVLPYY- 358 C VP+ CT+ NA+Y LL +L+D + SP + +K ++LFLP + +++ Y Sbjct: 132 QCAKVPEKCTRFNAIYQLLHFLVDRDFLSPQTIEYQVPSLKYSLLFLPTRKGASMMGIYL 191 Query: 359 KKLENSNMSYDNLV-IPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILT 417 LE+ ++ +DN I +D GLK LF +++ DT L + +F V Y RS+ +T Sbjct: 192 DNLESWDL-FDNYTSITGMDLGLKQKLFQHYLLLDTKYPVLAILAIFLSVSFYLRSVFIT 250 Query: 418 LFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQL 477 L + + SL I+YF Y F +FPF+NL ++I+ I A+ F++ +W Sbjct: 251 LMVLLTVVSSLMISYFLYKVAFRFTYFPFVNLTAVIILSSICANHTFVFFDLW------- 303 Query: 478 IKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIP 537 N+ +N SAG L Q + +TM H + + TT AFYASY+S I Sbjct: 304 ---NLSKSQN-------PSAG---LSQRVSQTMHHFAYLMLASCFTTGAAFYASYISNII 350 Query: 538 AINCFSVFAGTAVLVNFVLMMTWLPISV-----FIVDVKLYAKKKTFLDLVHKNV----- 587 AI CF+V+ GT+VLVN V MMTWLP S +I +Y + + + HK V Sbjct: 351 AIRCFAVYMGTSVLVNLVFMMTWLPSSAVLYERYIATTCVYKPEDYWKNTGHKRVALSLH 410 Query: 588 -------NEMWENIRIVLNRFTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLP--D 638 + E +++ + V KF ++ AL + +P L LP + Sbjct: 411 YVLRGLQKTLCETSKLLFEKLLPCGVIKFRYIWICWFAALAIGGAYISCSNPKLKLPTLE 470 Query: 639 SKQFQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPAS 698 S Q+F+ SHPFE+Y+ +Y +F+FERL + G G +MP+ +WG+ +DNG+H +P S Sbjct: 471 SSSVQVFRLSHPFERYDSEYCHQFMFERLER--GEGQRMPVTIIWGILPVDNGDHFNPKS 528 Query: 699 KGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYM-SRRCI 757 G LV D F+I P +Q WL FC ++K Q FY CF+E F +M SR+C Sbjct: 529 NGTLVADATFTIQSPDAQKWLFEFCQKVKNQTFYYLDTEQKSTVCFMEEFVRWMDSRQCS 588 Query: 758 DNIDKINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPI 817 + S CC FPY EVF CI K M L + RE G +F Sbjct: 589 QRDNSF--SLCCNQFSFPYGSEVFLHCI-KMM--LLEQGREGAETYDLGLRFDGEGN--- 640 Query: 818 IAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSDFQFYDLQRT 877 +AALV++F+++ YS +YS+ F+ E+ W E++ AP G++ GWF S + Y+LQ + Sbjct: 641 LAALVLQFQTVYHYSFNYSKAKHFYEEINLWVTEEMKTAPVGLQNGWFTSKLELYNLQHS 700 Query: 878 LASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILES 937 L++ T+V + LS A+ F+VL+ T N + SV ++TA+ + VT+ +LV+ W+LN +ES Sbjct: 701 LSTETMVVMGLSIAISFVVLLLTTWNVLLSVFSVTAIAGTVLVTVGLLVLLEWQLNAVES 760 Query: 938 VAISTSAGLAVDFSLHYALSY-TNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLR 996 + IS + GL+VDF+++Y +SY ++ +RV + AGV +L Sbjct: 761 LFISAAVGLSVDFTVNYCISYHLCPHSDRLSRVAFSLKQMSCATAMAASALFSAGVIMLP 820 Query: 997 SNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 + +L Y ++G F+++I +S +A+FF SL G Sbjct: 821 ATVLAYRKLGIFIMMIKCISCGFASFFFQSLCCFFG 856 >UniRef50_UPI000058420C Cluster: PREDICTED: similar to dispatched A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dispatched A - Strongylocentrotus purpuratus Length = 1232 Score = 458 bits (1129), Expect = e-127 Identities = 267/799 (33%), Positives = 435/799 (54%), Gaps = 53/799 (6%) Query: 250 CPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACDLDHC-NVPK 308 C SL Y AL+ K SC + ++DV V +L +CA ++ +L++ C C VP+ Sbjct: 428 CHPASLGQYAALLQNKPSCFDTTEDDVTHLVNLLTECAPHYVEESLLSNCASSSCPTVPR 487 Query: 309 YCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPR-SDTVLPYYK-KLENSNM 366 C NA YN+ YL+ SE+ S + + + T++ P+ SDT Y +L+ Sbjct: 488 KCKDRNAAYNIFHYLLPSESASKIASGDLEISFTLMISPISGFSDTTGQLYTDRLQGRKD 547 Query: 367 SYDNLV-IPAIDFGLKNALFDIWIIEDTWLIALG-GIFVFACVWIYTRSLILTLFLFAAI 424 +D+ + I AI K LF ++I D L+ + G+ +F +W+YT SL +TL + Sbjct: 548 LHDDFMKISAIGGQFKFDLFSSFLISDIVLVGIAVGVIMFI-IWLYTGSLFITLLTILDM 606 Query: 425 TFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVY 484 +L ++YF Y+ + L FFPF+N+L +++VLGIGADD F+Y+ +W+ G++ Y Sbjct: 607 AMALVMSYFVYLVIIRLPFFPFVNILAVILVLGIGADDTFVYLDLWRKFGEK-------Y 659 Query: 485 QENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSV 544 + E +V+IL+ET+ H+ +T+F+T+ TT+ A + S S I AI CF+V Sbjct: 660 SDR-----------EENMVRILQETLHHAAITMFVTSFTTSSALFFSITSSITAIKCFAV 708 Query: 545 FAGTAVLVNFVLMMTWLPISVFIVDVKLYAKK-KTFLDLVHKNVNEMWENIRIVLNRF-- 601 ++G A+L NF+ +TWLP V I + L K + L + + + ++ V F Sbjct: 709 YSGCAILFNFLFTLTWLPAIVIIEERYLSFKTCRNRKVLKCSRLGVVAQALKTVSRHFFE 768 Query: 602 TIICVTKFHIAFV--VVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFEQYEMQYR 659 ++ T F + +V +V LG +F P L LP +FQ+F S EQY+ + Sbjct: 769 KVLPETVFKLRYVWLIVFTLLGIGGGCAIFVYPALQLPTQSEFQIFVKSDFLEQYDQVFV 828 Query: 660 DKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSWL 719 + F FE+L + +KMP+++VWG+++ DNGN DP +G LV D F IS P+SQ WL Sbjct: 829 NYFDFEQLVQ-----SKMPIKFVWGLESKDNGNSWDPDDRGSLVLDNKFDISAPESQEWL 883 Query: 720 LGFCARIKGQPFYQQTLGPLLPNCFIESF-KMYMSRRCIDNIDKINRSPCCETSKFPYKK 778 L FC+ +K Q FY + + CFI+ F K+ M C + + SPCCE FPY Sbjct: 884 LNFCSDVKNQSFY-SSQSNIQDFCFIDVFKKLMMESPCDSPVYFRDLSPCCENYDFPYDP 942 Query: 779 EVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEM 838 E+F+ C S++ + + G+ R + + L++ F S YSL+Y + Sbjct: 943 ELFEQC-----ASMF-----VLLGGL--EHLTRFGEGQKLTGLLLSFTSSTRYSLNYESI 990 Query: 839 NKFFTEVEKWTQTELENAPAGMKCGWFLS----DFQFYDLQRTLASGTIVALLLSAALGF 894 N+F++E+ +W++ E++ AP + GWF+S F+DLQ++L +G +++ LS + Sbjct: 991 NEFWSEINQWSRQEMDKAPESISHGWFVSFSDNQLYFFDLQQSLVTGFPLSIGLSLGVAA 1050 Query: 895 IVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHY 954 +VL+ T NF+ ++ A+ ++ + VT+ LV W++NILES +S + GL+VDF++HY Sbjct: 1051 LVLLLTTWNFLITLFAIISISGTVFVTVGSLVFIGWEMNILESTIMSLAVGLSVDFTIHY 1110 Query: 955 ALSYTNA-SGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIM 1013 ++Y A +G++ ++ + AGV +L + + Y QIG FL LIM Sbjct: 1111 GVAYRIAPTGDRVSKAVHAMKQLTAAISTAALSTLMAGVCMLPATVFSYQQIGVFLALIM 1170 Query: 1014 TVSWTYATFFLCSLLHIVG 1032 VSW Y TFF SL + G Sbjct: 1171 GVSWAYGTFFFMSLCMVFG 1189 Score = 46.4 bits (105), Expect = 0.004 Identities = 21/61 (34%), Positives = 32/61 (52%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWENL 64 YS+FIVR L + +L++ + L+++P F DP GFE+R T + R E Sbjct: 252 YSKFIVRFPILFCVAILLLTVAAGAVAFTLYDIPQFDDPEKGFESRHTQIRDRLTGLELF 311 Query: 65 N 65 N Sbjct: 312 N 312 >UniRef50_UPI0000E4A16C Cluster: PREDICTED: similar to dispatched 1; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dispatched 1 - Strongylocentrotus purpuratus Length = 980 Score = 450 bits (1108), Expect = e-124 Identities = 270/903 (29%), Positives = 455/903 (50%), Gaps = 56/903 (6%) Query: 189 GTCGPPISDYAHLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDI 248 G+C S +V +TD+ + + ++ +C+ RT + Sbjct: 110 GSCTLDFSSRFKMVYRSTDSMEMFTSTGMKAVCQHDKENFRSYVGFDQICDYRTNGN--- 166 Query: 249 CCPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACDLDHCNVPK 308 CCP SL +L+ GK+SC +++ DV +L++C + L +VP Sbjct: 167 CCPSISLGQVTSLMVGKESCDDIDDSDVLGMKQLLEECIALYSRGCLGGDGGSICSDVPV 226 Query: 309 YCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVLPYYKKLENSNMSY 368 C+ ++ VY + YL + ++ M+ P+P D L Y + ++ Sbjct: 227 NCSANSGVYTIFHYLTPKNFALQVAKGAFDLQTVMVLQPVPNWDQTL-YDIYTDKPRLTD 285 Query: 369 DNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSL 428 D + + AI G K LF +++ D+ I G + V A +W+Y SL +T+ +I S+ Sbjct: 286 DAVQVVAIGGGFKFGLFGDYLLSDSIYIGFGCLAVVAIIWMYVGSLFVTIMTMFSIIMSM 345 Query: 429 GIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENG 488 +AYF Y +F L FFPF+N++ V+V+G+GADD F+YV IWK+ K E+G Sbjct: 346 VVAYFLYHTIFRLVFFPFVNVITAVLVIGVGADDCFVYVDIWKLAKK----------EHG 395 Query: 489 VLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGT 548 G V +L ET++H++ T+F+T+LTTA A +A VS I A+ CFSVFAGT Sbjct: 396 --------GGRENRVLVLRETLKHAVTTMFVTSLTTASALFAGCVSSITAVRCFSVFAGT 447 Query: 549 AVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKN-----VNEMWENI----RIVLN 599 ++LVNFVL +TW+P +V + ++ L +++++ R + Sbjct: 448 SILVNFVLTVTWIPAAVMFHEKYFICDEEGQEGLCRCCGLCFFPGRIYDHVSRVGRKLFE 507 Query: 600 RFTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFEQYEMQYR 659 + I + K +++++ LG VVF P L LP +FQ+F+ SH EQY+ Y+ Sbjct: 508 EYLPIIIVKLRFLWILLLSGLGIGGFCVVFVEPRLRLPSQSEFQVFRKSHILEQYDQVYK 567 Query: 660 DKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSWL 719 + F FE S++ KMP VWG++ +DNGNH DP S G V D+NF + P++Q+WL Sbjct: 568 EMFNFETDSEN-----KMPAYIVWGIEPVDNGNHWDPDSDGTTVIDKNFDVKSPEAQTWL 622 Query: 720 LGFCARIKGQPFYQQTLGPLLPN--CFIESFKMYMSRRCIDNIDKINRSPCCETSKFPYK 777 FC ++ F+ + PN CFI+ FK +M + C+ +I SPCC FPY Sbjct: 623 YNFCTDLRNASFHDNNMA-TAPNEFCFIDLFKGFMEKTCLGDI-----SPCCGQRTFPYS 676 Query: 778 KEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSE 837 +F+ C+ + Q +L G P ++ ++ +V+ ++ + YSLSY Sbjct: 677 SSLFNRCVPLFYGIVCQ---DLEACGSYIPGLWFNSDNEVV-GMVLVIKTSIKYSLSYDT 732 Query: 838 MNKFFTEVEKWTQTELENAPAGMKCGWFLSD----FQFYDLQRTLASGTIVALLLSAALG 893 + +F+++V + + AP G++ GWF+SD +F+DLQ+ LA GT +++ +S Sbjct: 733 IGQFWSDVNDFIADRMAEAPTGLRRGWFISDIDLQMRFFDLQQGLARGTPLSVGMSLVFA 792 Query: 894 FIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLH 953 VL+ N + ++ A+ A+ + V IA +V+ W+LNI ES +S + GL+VDF++H Sbjct: 793 ACVLLMTIRNVLVTIYAMYAIACAVFVVIASVVLLGWELNIFESTVLSLAVGLSVDFTVH 852 Query: 954 YALSYTNAS-GNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLI 1012 ++Y A+ ++++R + AG +L + +L Y Q+G FL+++ Sbjct: 853 LGVAYRQATESDRTSRSMHALQTLGSAVTLAALTTLVAGGCMLPATVLSYVQLGTFLMIV 912 Query: 1013 MTVSWTYATFFLCSLLHIVGRSSIKESPSRE---RKPVSRVNSVSSGVPNLESHELEHLA 1069 M VSW Y F SL +G + S+ R+ N++ G+ E +H+ Sbjct: 913 MVVSWVYGLFLFISLCRTIGPQGMFAQISKSCCCREQNVAENNLGVGITIEEHVHAQHVD 972 Query: 1070 DSN 1072 S+ Sbjct: 973 TSD 975 Score = 46.0 bits (104), Expect = 0.006 Identities = 21/56 (37%), Positives = 36/56 (64%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIA 60 YS+F+V + +V+ V ++ I+ + ++L+EL SF +P GFE RGT ++ R A Sbjct: 10 YSQFLVTYPSVVMLLVLLVVIISAGLGVLLNELSSFDNPTKGFEARGTVISGRLKA 65 >UniRef50_UPI0000E4776B Cluster: PREDICTED: similar to dispatched A, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dispatched A, partial - Strongylocentrotus purpuratus Length = 1022 Score = 438 bits (1080), Expect = e-121 Identities = 290/876 (33%), Positives = 438/876 (50%), Gaps = 78/876 (8%) Query: 184 LNYASGTCGPPISDYA----HLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXC 239 +N GT ++YA LV + DN L S + + +C S Sbjct: 142 INPEDGTSCMQPAEYASYQVRLVFSRVDNMHLFSAEAMRSMCSLYSSLFLKNTTEIPPNL 201 Query: 240 QRTTHSEDICCPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAAC 299 + C SL Y A I GKDSC + +DV K +L++C+ +F L C Sbjct: 202 RE--------CEPASLGRYAAFIGGKDSCSGILDDDVMKLRQLLQECSPFFVRNVLRPNC 253 Query: 300 DLDH-C-NVPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVLPY 357 + C NVP CT NAV+N+L YL+ P+N+A++ + + L T Sbjct: 254 GIQGTCPNVPSNCTMKNAVFNILQYLL------PINSAEQIARGDFDIVSLALMVTPFYL 307 Query: 358 YKKL-----ENSNMSYDN----LVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVW 408 Y L +N+ M D + A+ G K LF +++ + + +G + VW Sbjct: 308 YSDLGQDIYKNNIMGLDIGDGITKLSAVGGGYKYDLFSDFLVSNCMYLVVGIGLILVIVW 367 Query: 409 IYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVK 468 +YT SL +T+ + SL +YF Y VF + FFPFMN+L V+V+GIGADDAF+Y+ Sbjct: 368 LYTGSLFVTIMTILDMIMSLVFSYFLYTVVFKMPFFPFMNVLAFVLVIGIGADDAFVYID 427 Query: 469 IWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAF 528 IWK + ++ D E VL +L++T+ H+ +T+F+T+ TT+ A Sbjct: 428 IWKKMRQR--HDGT--PEKRVL--------------VLQDTLHHAAITMFVTSFTTSTAL 469 Query: 529 YASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLY---AKKKTFLDLVHK 585 ++S +S I A+ C +V+AG A+L+NFV +TWLP V I D L +++ + Sbjct: 470 FSSIISSITALRCLAVYAGCAILINFVYTVTWLPAIVVIEDKYLQFRRCRERITPCECYI 529 Query: 586 NVNEMWENIRIVLNRF---TI-ICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLPDSKQ 641 + EM + + + F T+ + V K ++V+ LG +F P L LP Sbjct: 530 TIKEMSKVLSGCIRSFWETTLPLVVFKLRYLWIVLFTLLGVGGACAIFVKPKLQLPTKNA 589 Query: 642 FQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGH 701 FQ+F +S EQY+ Y+ FLFE+ G MP+ +VWGV DNGN DP KG Sbjct: 590 FQVFISSDYMEQYDQIYKKDFLFEK-----GEEKLMPIFFVWGVVPNDNGNPWDPDDKGS 644 Query: 702 LVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNID 761 +VFD +F++S+ SQ WLL FC I+ Q FY + CFIE K M + C ++ Sbjct: 645 IVFDRSFNLSNKDSQEWLLAFCHDIRNQTFYSKA-NKGSDFCFIEILKSVMEQPCENHSL 703 Query: 762 KINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAAL 821 N PCC +KFPY + +FD C L T R G +F +K + L Sbjct: 704 PFNPEPCCNQTKFPYDQGLFDHC----APFLTSTLR------CDGVRFGEKSK---LTGL 750 Query: 822 VVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWF--LSDFQ--FYDLQRT 877 + F S +L Y +NKF+ +++ W + +++ AP GM GWF S+ Q F+DLQ + Sbjct: 751 QLSFTSTTADTLVYENINKFWYQIDGWVKEKMKTAPPGMAGGWFGSYSENQMFFFDLQES 810 Query: 878 LASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILES 937 LA GT +++ LS + VL+ T N + ++ A ++ + VTI LV+ W+LNILES Sbjct: 811 LARGTKMSIGLSLGMATTVLLFTTRNLLITLFATLSIGGTVFVTIGSLVLLGWELNILES 870 Query: 938 VAISTSAGLAVDFSLHYALSYTNA-SGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLR 996 +S + GL+VDF++HY ++Y A ++++R + AG +L Sbjct: 871 TVMSLAVGLSVDFTIHYGVAYGLAPHKDRASRSTFAMVQLTSAITTAAFSTFIAGAVMLP 930 Query: 997 SNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 S +L Y QIG FL L+MTVSW YA FF L G Sbjct: 931 SVVLCYQQIGIFLTLVMTVSWFYANFFFMPLCRAFG 966 >UniRef50_Q96F81 Cluster: Protein dispatched homolog 1; n=41; Euteleostomi|Rep: Protein dispatched homolog 1 - Homo sapiens (Human) Length = 1011 Score = 436 bits (1074), Expect = e-120 Identities = 235/650 (36%), Positives = 377/650 (58%), Gaps = 48/650 (7%) Query: 403 VFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADD 462 V + +YT+S+ +TL AI SL ++YF Y VF+ FFPFMNL ++I++GIGADD Sbjct: 1 VLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFHFEFFPFMNLTALIILVGIGADD 60 Query: 463 AFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTL 522 AF+ +W Y + D + ET+ + T++H+ +++F+T+ Sbjct: 61 AFVLCDVWN------------YTK---FDKPHAETSETVSI-----TLQHAALSMFVTSF 100 Query: 523 TTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISV-----FIVDV------- 570 TTA AFYA+YVS I AI CF V+AGTA+LVN+VLM+TWLP V +++++ Sbjct: 101 TTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFTCFKKP 160 Query: 571 --KLYAKKKTFL---DLVHKNVNEMWENIRIVLNRFTIICVTKFHIAFVVVMGALGFISL 625 ++Y K + HK + + E RI + V KF ++ AL Sbjct: 161 QQQIYDNKSCWTVACQKCHKVLFAISEASRIFFEKVLPCIVIKFRYLWLFWFLALTVGGA 220 Query: 626 VVVFYSPGLHLP--DSKQFQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVW 683 +V +P + LP + +FQ+F++SHPFE+Y+ +Y+ F+FER+ G MP+ +W Sbjct: 221 YIVCINPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHH--GEELHMPITVIW 278 Query: 684 GVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNC 743 GV DNGN ++P SKG L D +F+I+ P SQ+W+L FC +++ Q F+ QT +C Sbjct: 279 GVSPEDNGNPLNPKSKGKLTLDSSFNIASPASQAWILHFCQKLRNQTFFYQTDEQDFTSC 338 Query: 744 FIESFKMYMSRRCIDNIDKINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPG 803 FIE+FK +M + + D+ PCC FPYK+E+F+ CI +A+ L ++ Sbjct: 339 FIETFKQWMENQ---DCDEPALYPCCSHWSFPYKQEIFELCIKRAIMELERSTGYHLDSK 395 Query: 804 VAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCG 863 GP+F + I A+V+EF+S ++L+Y +M++F+ EV+ W +EL +AP G+ G Sbjct: 396 TPGPRFDIN---DTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNG 452 Query: 864 WFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIA 923 WF+S+ +FYDLQ +L+ GT++A+ LS A+ F V++ T N + S+ A+ ++ + VT+ Sbjct: 453 WFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIISIAGTIFVTVG 512 Query: 924 VLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNA-SGNKSARVKYXXXXXXXXXXX 982 LV+ W+LN+LESV IS + GL+VDF++HY ++Y A ++ +V + Sbjct: 513 SLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRVGSAMAM 572 Query: 983 XXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 AG ++ S +L Y+Q+G F++LIM +SW +ATFF + +G Sbjct: 573 AALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLG 622 >UniRef50_Q9C0C1 Cluster: Protein dispatched homolog 2; n=19; Eutheria|Rep: Protein dispatched homolog 2 - Homo sapiens (Human) Length = 1301 Score = 420 bits (1034), Expect = e-115 Identities = 271/874 (31%), Positives = 437/874 (50%), Gaps = 69/874 (7%) Query: 191 CGPPISDYAHLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICC 250 CGPP YA LV +T + SL + + +C+ + CQRT ++ CC Sbjct: 179 CGPPEKSYAKLVFMSTSSGSLWNLHAIHSMCRMEQDQIRSHTSFGAL-CQRTAANQ--CC 235 Query: 251 PVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAAC------DLDHC 304 P WSL NY+A++S + SC++ + D + + +L+ CA Y+H+ L+ +C C Sbjct: 236 PSWSLGNYLAVLSNRSSCLDTTQADAARTLALLRTCALYYHSGALVPSCLGPGQNKSPRC 295 Query: 305 -NVPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKF--VKNTMLFLPLPRSDTVLPYY-KK 360 VP C+Q +A+Y LL +L+D + SP + +K ++LFLP P+ +++ Y + Sbjct: 296 AQVPTKCSQSSAIYQLLHFLLDRDFLSPQTTDYQVPSLKYSLLFLPTPKGASLMDIYLDR 355 Query: 361 LENSNMSYDNLV-IPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLF 419 L DN + +D GLK L ++++DT L + +F + +Y RSL LTL Sbjct: 356 LATPWGLADNYTSVTGMDLGLKQELLRHFLVQDTVYPLLALVAIFFGMALYLRSLFLTLM 415 Query: 420 LFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIK 479 + + SL +A+F Y F + +FPF+NL ++++ + A+ I+ +W++ QL Sbjct: 416 VLLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALLLLSSVCANHTLIFFDLWRLSKSQL-- 473 Query: 480 DNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAI 539 S G L Q + TM H + ++ LTT+ AFYASY+S +PA+ Sbjct: 474 ---------------PSGG---LAQRVGRTMHHFGYLLLVSGLTTSAAFYASYLSRLPAV 515 Query: 540 NCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLY-------------AKKKTFLDLVHKN 586 C ++F GTAVLV+ L + WLP S + + L + + L +H+ Sbjct: 516 RCLALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRWEGSAPRRLLLALHRR 575 Query: 587 VNEMWE----NIRIVLNRFTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLPDSKQ- 641 + + R++ R V KF ++ AL + SP L LP Sbjct: 576 LRGLRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYIAGVSPRLRLPTLPPP 635 Query: 642 -FQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKG 700 Q+F+ SHPFE+++ +YR FLFE+L + G G MP+ VWGV +D G+ +DP S Sbjct: 636 GGQVFRPSHPFERFDAEYRQLFLFEQLPQ--GEGGHMPVVLVWGVLPVDTGDPLDPRSNS 693 Query: 701 HLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPN-CFIESFKMYMSRRCIDN 759 LV D FS S P++Q WLL C R + Q F+ TL P CF+E+ + +M + Sbjct: 694 SLVRDPAFSASGPEAQRWLLALCHRARNQSFFD-TLQEGWPTLCFVETLQRWMES---PS 749 Query: 760 IDKINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIA 819 ++ CC S FP+ + F C+ M +L Q P G LR +A Sbjct: 750 CARLGPDLCCGHSDFPWAPQFFLHCL--KMMALEQGPDGTQDLG------LRFDAHGSLA 801 Query: 820 ALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSDFQFYDLQRTLA 879 ALV++F++ S Y++ F+ EV W EL AP G++ GWF S + Y LQ +L+ Sbjct: 802 ALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSLS 861 Query: 880 SGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVA 939 + V L L+ AL F L+ T N S+ ++ A+ + +T+ +LV+ W+LN E++ Sbjct: 862 TEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEALF 921 Query: 940 ISTSAGLAVDFSLHYALSY-TNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSN 998 +S S GL+VDF+++Y +SY ++ +RV + AGV +L + Sbjct: 922 LSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPAT 981 Query: 999 LLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 +L Y ++G L+++ VS +A+FF SL G Sbjct: 982 VLLYRKLGIILMMVKCVSCGFASFFFQSLCCFFG 1015 Score = 48.0 bits (109), Expect = 0.001 Identities = 25/78 (32%), Positives = 38/78 (48%) Query: 1 MLAAYSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIA 60 M +YS+ I VL + + T+ L+ LP FS P++GFE R T + + + Sbjct: 57 MPKSYSQLIAEWPVAVLMLCLAVIFLCTLAGLLGARLPDFSKPLLGFEPRDTDIGSKLVV 116 Query: 61 WENLNDETRPSKRLAVNP 78 W L T P K L ++P Sbjct: 117 WRALQALTGPRKLLFLSP 134 >UniRef50_Q6R5J1 Cluster: Dispatched 2; n=3; Clupeocephala|Rep: Dispatched 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1476 Score = 415 bits (1022), Expect = e-114 Identities = 270/892 (30%), Positives = 446/892 (50%), Gaps = 82/892 (9%) Query: 191 CGPPISDYAHLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHS----- 245 C P YA LV + +++SL S K + +C+ + CQ + Sbjct: 289 CNAPGERYAQLVFRSGNSASLWSLKAIYSMCQMEQTQIRSGPQFDKL-CQVKSEFYGSMV 347 Query: 246 EDICCPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACD----L 301 ++ CCP WSL NY+A+++ SC +L + V +++ +L+ CA Y+H+ +L+A+C Sbjct: 348 KNECCPSWSLGNYLAVLNNISSCFSLTSQQVSESLGLLRFCAPYYHDGSLIASCTERSKF 407 Query: 302 DHC-NVPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKF--VKNTMLFLPLPRSDTVLPYY 358 C +VP C + ++++ +L YL+D + P K +K +++FLP+ +SD+++ Y Sbjct: 408 GRCASVPHRC-KLSSIFQILHYLVDKDFLGPQTVEYKVPSLKYSIVFLPVEKSDSLMNIY 466 Query: 359 -KKLENSNMSYDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILT 417 LE ++Y+N I +D G+K LF ++ D+ L + + + +Y +SL + Sbjct: 467 LDHLEGHKLTYNNTTITGMDLGIKQKLFKYYLARDSIYPVLAALALLITIGLYLKSLFIA 526 Query: 418 LFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQL 477 A+ SL +YFFY F L FFP +NL + ++LG + A +V WK+ Sbjct: 527 AMSLVAVILSLSTSYFFYKVAFRLTFFPLLNLAAVFVLLGSCLNQALTFVDFWKL----- 581 Query: 478 IKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIP 537 L N + E + ++L+E M + I+ ++ LT++V FY+ Y+S I Sbjct: 582 -----------QLSHNPPAVPEKRMNRVLQE-MGYLII---VSGLTSSVTFYSGYISSIT 626 Query: 538 AINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKKT-----FLDLVHKNVNEMWE 592 A+ C++V+ G+A L+N + + WLP ++ + + T + KN WE Sbjct: 627 AVRCYAVYLGSASLINTLFALVWLPCTLILQERYAVLSSNTVGKVAWKPCCSKNAGGFWE 686 Query: 593 N-------------IRIVLNRFT----------IIC-VTKFHIAFVVVMGALGFISLVVV 628 +R + F+ + C V KF ++ L + Sbjct: 687 TSSRKRCLFTFRQKLRTLGRGFSDTSNLLFLKILPCGVVKFRYIWICWFAVLAAGGTYIS 746 Query: 629 FYSPGLHLP--DSKQFQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVK 686 PG+ LP DS+ QLF++SHPFE+Y+ +YR +F+FER+ KD G M L +WG+ Sbjct: 747 CVDPGMKLPTSDSRTTQLFRSSHPFERYDAEYRHQFMFERM-KD-GEDEPMMLTLIWGIV 804 Query: 687 AIDNGNHMDPASKGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTLGP---LLPN- 742 DNG+H DP S G L D F++S ++Q WL C +I+ Q FY N Sbjct: 805 PSDNGDHFDPKSNGSLSVDPGFNMSSLQAQIWLRDLCGKIQNQTFYSPLSAEQDTAEDNV 864 Query: 743 CFIESFKMYMS-RRCIDNIDKINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFM 801 CF+E ++S RRC ++ D S CC FPY VF+ C+ + + R + Sbjct: 865 CFVEHLIHWVSIRRCSESEDAF--SFCCNNIPFPYPPRVFEQCLSMMVAEQHAEGR---L 919 Query: 802 PGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMK 861 P G +F + IAALVV F+++ YS +Y+ M++F+ E+ W E+ APAG++ Sbjct: 920 PSAGGLRFDSEGR---IAALVVIFKTVQLYSFNYNRMSQFYQEILSWFNREISKAPAGLQ 976 Query: 862 CGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVT 921 GWF+S YDLQ+ L+S T+ S AL F +L+ T N SV A+ S T Sbjct: 977 RGWFVSQLGLYDLQQCLSSETLEVAGFSVALTFALLLLTTWNIPLSVYVSIAVAGSVFAT 1036 Query: 922 IAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNA-SGNKSARVKYXXXXXXXXX 980 + +LV+ W+LN +E++ IS +AGL+VDF +Y +SY+ A ++ RV + Sbjct: 1037 VGLLVLLEWQLNGVEALFISAAAGLSVDFVANYCISYSLAPHSDRLGRVAHSIKRMGCPV 1096 Query: 981 XXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 G+ +L + L + ++G FL+L+ V+ +ATFF SL G Sbjct: 1097 ATGAGAYFCVGIIMLPATALLFRKLGIFLLLVKCVACGFATFFFQSLCCFFG 1148 Score = 58.8 bits (136), Expect = 8e-07 Identities = 26/81 (32%), Positives = 46/81 (56%) Query: 4 AYSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWEN 63 +YS+ IV + VL + +++ ++ ++ LP FSDP++GFE RGT ++ R W Sbjct: 176 SYSQVIVEYPMTVLISCTLVLFACSLAGILTGPLPDFSDPLLGFEPRGTDISVRLATWTR 235 Query: 64 LNDETRPSKRLAVNPKEIEDQ 84 L T P K L+ P ++ ++ Sbjct: 236 LKQNTGPGKPLSPVPWQLTEK 256 >UniRef50_Q4SWS4 Cluster: Chromosome undetermined SCAF13541, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF13541, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1251 Score = 406 bits (999), Expect = e-111 Identities = 234/687 (34%), Positives = 378/687 (55%), Gaps = 63/687 (9%) Query: 191 CGPPISDYAHLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICC 250 C P Y+ LV T+ + +L S + ++ +C + CQRT + CC Sbjct: 351 CDVPGDHYSRLVFTSAEGKNLWSIQAIKSMCNLDNARVRSHRDYWSL-CQRTNDAS--CC 407 Query: 251 PVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAAC---------DL 301 P W++ NYIA+++ + SC + ++DV IL+ CA Y+HN TL C L Sbjct: 408 PSWTIGNYIAVLTNRSSCQKITEQDVSHIFRILRSCAKYYHNGTLGPDCWDMTLRRKDQL 467 Query: 302 DHCNVPKYCTQHNAVYNLLFYLIDSEAFSP--LNNAQKFVKNTMLFLPLPRSDTVLPYY- 358 NVPK CT++NAVY +L +L+D + SP L + +K++MLF P + D+++ Y Sbjct: 468 KCANVPKKCTKYNAVYQILHFLVDKDFLSPKSLESPPPVLKHSMLFSPTKKGDSMMNIYL 527 Query: 359 KKLENSNMSYDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTL 418 EN N S + I+FG+K+ LF +++ DT A+ + V + +YTRS+ +TL Sbjct: 528 DNFENWNSSDGITTVTGIEFGIKHDLFQDYLLTDTVYPAIAIMIVLLVMCVYTRSVFITL 587 Query: 419 FLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLI 478 AI SL +AYF Y VFN FFPFMNL ++I++GIGADDAF+ +W Sbjct: 588 MTIIAIISSLIVAYFLYRMVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWN------- 640 Query: 479 KDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPA 538 Y + D + ET+ + T++H+ +++F+T+ TTA AFYA+YVS I A Sbjct: 641 -----YTK---FDKPRAELSETVGM-----TLQHAALSMFVTSFTTAAAFYANYVSNITA 687 Query: 539 INCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKL----------YAKKKTFLDLVHKNVN 588 I CF V+AGTA+LVN+VLM+TWLP V + + L + ++ D ++ Sbjct: 688 IRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLPNALACSKPPHQERGCCADAFWAGLS 747 Query: 589 E--------MWENIRIVLNRFTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLP--D 638 + + E R+ + V K +++ A+ VV +P + LP + Sbjct: 748 QKAGKCLLALSETSRVFFEKVLPCIVIKLRYLWLLWFLAITVGGAYVVCVNPKMKLPSLE 807 Query: 639 SKQFQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPAS 698 +FQ+F++SHPFE+Y+ +Y+ F+FER+ G +P+ +WGV +DNG+ ++P + Sbjct: 808 VAEFQVFRSSHPFERYDAEYKKLFMFERVHH--GEELHVPITIIWGVTPVDNGDPLNPKN 865 Query: 699 KGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCID 758 G LV D +F+I+ P++Q W+L FC +++ Q F Q+ +CFIE+FK +M R Sbjct: 866 TGKLVLDTSFNITSPQAQLWILNFCQKLRNQSFVFQSEEQDFISCFIETFKQWMENR--- 922 Query: 759 NIDKINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPII 818 + ++ + PCC S FPYK++VF+ CI +A+ L ++ G GP+F + I Sbjct: 923 DCEEASVYPCCSQSTFPYKQDVFELCIKRAIMELDRSTSYHLNSGTPGPRFDIN---DTI 979 Query: 819 AALVVEFESIVPYSLSYSEMNKFFTEV 845 A+V+EF+S ++L+Y +M +F++EV Sbjct: 980 RAIVLEFQSTHLFTLAYEKMYQFYSEV 1006 Score = 58.4 bits (135), Expect = 1e-06 Identities = 26/81 (32%), Positives = 45/81 (55%) Query: 4 AYSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWEN 63 +Y+ I +VL ++L +V ++ +++ +LP FSDP+ GFE RGT + R + W+N Sbjct: 240 SYAELIADWPVVVLGVCTVLIVVCALVGILVPDLPDFSDPLRGFEPRGTAIGQRLVTWDN 299 Query: 64 LNDETRPSKRLAVNPKEIEDQ 84 + T LA P + D+ Sbjct: 300 MVKNTGYKATLANYPFKYADE 320 >UniRef50_UPI0000588F35 Cluster: PREDICTED: similar to dispatched A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dispatched A - Strongylocentrotus purpuratus Length = 1011 Score = 405 bits (997), Expect = e-111 Identities = 263/871 (30%), Positives = 421/871 (48%), Gaps = 63/871 (7%) Query: 191 CGPPI----SDYAHLVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSE 246 CG P+ S + + ++ LL+ ++ +C+ Q C + + S Sbjct: 137 CGNPMTAGASSFRAVYAPSSSAVELLTLDSLLSMCQ-QDDTFVRNSSTFKTVCTKQSDSS 195 Query: 247 DICCPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACDLD-HCN 305 CCP WS+PNYI+ ++G+ SC +L ED+ A +L +CA Y+ + L A C +C Sbjct: 196 SQCCPSWSIPNYISALNGRSSCYDLTAEDIAFARLLLLECAPYYTSGALSAECGSGTNCT 255 Query: 306 -VPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFL----PLPRSDTVLPYYKK 360 VP CT +NA+Y + F S+ + T L + PL + Y Sbjct: 256 GVPSNCTTYNAIYFMFFANSPSDFSIQVAETGDLTLTTSLQIVSLNPLVAAGDRTLYNDA 315 Query: 361 LENSNMSYDNLVIPAIDFG--LKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTL 418 + N+ I AI K L +++D +GG + +W+Y SL + + Sbjct: 316 VNRRNVDNGITKIEAIGTNRLAKYFLISEPLMQDLIYAGVGGAIMILLIWVYLSSLFIAI 375 Query: 419 FLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLI 478 + I FS+ +AYFFY VF L FF F N+L IV++LG+GADDAFI+ I++ ++ Sbjct: 376 MVIFEIIFSVALAYFFYYVVFRLTFFAFGNMLAIVLILGVGADDAFIFYDIFENTRRK-- 433 Query: 479 KDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPA 538 + + E ILV ETM+H+ T+F+T+LTTA A + + S + Sbjct: 434 --------------HPDAKQEFILV----ETMKHAFPTMFVTSLTTASALFVNVASSVTN 475 Query: 539 INCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKL----YAKKKTFLDLVHKNVNEMWENI 594 I + +++GT VL NF+ MTW P + I D L A + HK N W + Sbjct: 476 IRLYGIYSGTVVLCNFLFTMTWSPATAIIYDRHLRLLFQASSASKERRFHKMRNH-WHTL 534 Query: 595 RIVLNR----FTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLPDSK-QFQLFQTSH 649 R L R + + K ++++ L +L+VVF+ P L + +FQ+F H Sbjct: 535 RNFLRRIFEVYLPMLAFKLRCLWILLFTGLSIGALMVVFWKPQLRASTANTEFQIFTLKH 594 Query: 650 PFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFS 709 P E+Y+ +R F ER T +P VWG +DNG+ DP S+GH+ D++F+ Sbjct: 595 PLERYDQVFRSTFDIERAKL-----TPLPFIVVWGTVPVDNGDPFDPGSRGHVQLDDSFN 649 Query: 710 ISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNIDKINRSPCC 769 + DP+SQ WLL FC+ ++ Q FY + +CFIE K++M CI + + SPCC Sbjct: 650 LDDPESQVWLLDFCSEVRQQGFYNSP-SVVYEDCFIEKMKIFMETPCIPSSIGTDLSPCC 708 Query: 770 ETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPG---VAGPKFLRSAKPPIIAALVVEFE 826 + FPY ++ C K Y F+ G A P F R I A +++F+ Sbjct: 709 GQTSFPYSADLLKLCAPK-----YAAYTCEFISGGCPTAIPGF-RFDSENNINAFLIQFQ 762 Query: 827 SIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWF--LSDFQ-FY-DLQRTLASGT 882 S L ++ +++ W + +++ AP G++ GWF LS Q FY DL L T Sbjct: 763 STAISQLEFAPAKEYYDTALAWVEEKVKTAPVGLQGGWFGTLSLAQPFYVDLIIQLKRDT 822 Query: 883 IVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAIST 942 +AL LS + IVL+ N + + A ++ S ++A+ V+ W+L + ESV I Sbjct: 823 PLALGLSLIIAMIVLLITNRNVLIAFYAALSIGGSVVTSVAIFVLIGWELKVFESVLIIL 882 Query: 943 SAGLAVDFSLHYALSYTNA-SGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLP 1001 + GLA DF++HY ++Y A ++ R +Y G +L +N+L Sbjct: 883 TVGLATDFTIHYGVAYRLAPHDDRRNRAQYSLSTLASANTMAALSSFMIGAMMLPANVLI 942 Query: 1002 YSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 + Q+G L +++ VSW++ TFF L ++ G Sbjct: 943 FYQLGIALEVVIAVSWSFGTFFFLPLCYVSG 973 Score = 39.5 bits (88), Expect = 0.50 Identities = 17/59 (28%), Positives = 32/59 (54%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWEN 63 ++R R ++++ I+ ++LT + + +H P+F D G E RGT + R I E+ Sbjct: 34 HARLFTRFPFIMILLQVIMIVLLTFLTVYIHGPPTFEDASSGIEARGTPIHDRIIPLES 92 >UniRef50_UPI0000587C88 Cluster: PREDICTED: similar to dispatched 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dispatched 1 - Strongylocentrotus purpuratus Length = 1006 Score = 391 bits (963), Expect = e-107 Identities = 246/868 (28%), Positives = 425/868 (48%), Gaps = 62/868 (7%) Query: 191 CGPPISDYAHLVITNTD--NSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDI 248 CG P +V ++ N +LL+ +++ +C+ C+R + Sbjct: 151 CGTPDFSGFRMVFESSSPSNPNLLTREHLISMCRHDDVIVRNTSHFQTA-CKRD--ASGA 207 Query: 249 CCPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACDLD-HCN-- 305 CC WSL NYIA ++ + SC ++ +DV + + +L+ CA ++ + L C + +C+ Sbjct: 208 CCATWSLANYIATMNNRVSCFDITGDDVDRMMPLLQHCAPFYSSGDLQPGCSEEQNCSSR 267 Query: 306 VPKYCTQHNAVYNLLFYLIDSEAF-SPLNNAQKFVKNTMLFLPLPRSDTVLP--YYKKLE 362 VP C ++ L+FY + +F S LN + + PL L Y + + Sbjct: 268 VPFECIGYDDAVYLIFYALTPGSFASSLNTVDAELNLNLHLYPLSDDADALKLIYLENIY 327 Query: 363 NSNMSYDNLVIPAIDFGLKNALFDIW---IIEDTWLIALGGIFVFACVWIYTRSLILTLF 419 + + ++ I + + + D + +G + A +WIY SL+ + Sbjct: 328 HQPLDDGVTMVTGIGVDTRKVKLSTYSNALRGDFLYVGIGCAVIVAIIWIYMESLLTAIL 387 Query: 420 LFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIK 479 + + SL I YFF+ VF FFPFM+LL +++V+ +GADDAFI++ IW+ Sbjct: 388 VLLQMALSLMIGYFFHFVVFRFAFFPFMSLLAVILVIAVGADDAFIFMDIWRK------- 440 Query: 480 DNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAI 539 N+ + + V L T++ + +T+F+T+ T A A + + S + + Sbjct: 441 -------------NLKLSTDHSRVNDLRTTLKEATLTMFVTSFTNAAALFVTAFSAVTTV 487 Query: 540 NCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVNEMWENIRI--- 596 FS+++G +L NF L + WLP +V I + ++ +K T K+ + +RI Sbjct: 488 RLFSIYSGMVILANFCLTIIWLPPAVMISEKYIHRRKVTSKPPSAKHKVFFAKTMRILGD 547 Query: 597 VLNRFTIICVTKFHIAF----VVVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFE 652 +++ F + + KF + F +++ L SLVVVF+ PGL LP L++ +HP E Sbjct: 548 IIHSFFRVHLPKFVLRFRFVWLILFPILFIGSLVVVFFKPGLSLPSGGDILLYKPAHPIE 607 Query: 653 QYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISD 712 +Y+ + KF FE S +++P+ VWG+ +DNG+H DP +GH++ + ++S Sbjct: 608 RYDQVLKWKFDFENASV-----SQLPIIVVWGIIPLDNGDHWDPDDRGHVLLEAPLNLSS 662 Query: 713 PKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNI---DKINRSPCC 769 SQ WLL FC ++ Q FYQ+ + +CFIESF +M + C+ D+I+R CC Sbjct: 663 QDSQQWLLNFCQEMRRQGFYQRPT-MITEDCFIESFGQFMQQPCVQPAIEGDQIDR--CC 719 Query: 770 ETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESIV 829 FP +FD C+ + + Y+ R + GP+F I+AL V+FES V Sbjct: 720 NQDTFPLPSVLFDECLPQFI--AYRCKRYPCNSPIPGPRF---GPNNSISALYVQFESSV 774 Query: 830 PYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFL--SDFQFYDLQRTL--ASGTIVA 885 + E N+F+ W +++AP G++ GWF+ SD Q Y L TL A G + Sbjct: 775 LERFEFQETNEFWNNASSWVNDRMQSAPEGLRKGWFVTFSDKQPYFLDNTLGFARGARTS 834 Query: 886 LLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAG 945 L LS A+ V++ + N + + + ++ + +A LV W+LN+ ES ++ G Sbjct: 835 LALSIAIAAGVVLLTSRNIIMVLLIILSIGGAVITALAALVFAGWELNVFESSMMALIVG 894 Query: 946 LAVDFSLHYALSYTNA-SGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQ 1004 L VDF+LHY ++Y + ++ +R Y AG +L ++++ ++Q Sbjct: 895 LTVDFTLHYGVAYLHGPDTDRRSRSHYSISTISRANSMAALSSFVAGSLMLPADVIIFTQ 954 Query: 1005 IGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 +G L +IM SW TFF SL +G Sbjct: 955 LGIALQIIMVCSWATGTFFFISLCRTIG 982 >UniRef50_A7RVB1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 810 Score = 364 bits (895), Expect = 8e-99 Identities = 242/857 (28%), Positives = 419/857 (48%), Gaps = 84/857 (9%) Query: 201 LVITNTDNSSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICCPVWSLPNYIA 260 L +T +SL + K+ + +C + C + T+ CC +SL N +A Sbjct: 1 LAFESTSGASLFNAKSFKEMCYLEEDIVQKNSLFQTY-CLKDTNGN--CCSSYSLGNMVA 57 Query: 261 LISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACD---------LDHCN-VPKYC 310 + K SC ++ DV +A T+++ CA YF L C +++C VP C Sbjct: 58 SVMRKSSCQDITDSDVNQASTLIESCAPYFVKGLLKNTCSCNTLINGTTVNNCPAVPCLC 117 Query: 311 TQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVL---PYYKKLENSNMS 367 Q A ++ YL D++ L KF+K + FLPL D Y KL+ S + Sbjct: 118 FQDQATLLVMNYLTDNKFL--LTPKDKFLKYALSFLPLSWWDNDFYKDVYDSKLKKSLPN 175 Query: 368 YDNLVIPAIDFG-LKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITF 426 + + + DFG K LF +I++ A+ + + + +Y S+I+ +I F Sbjct: 176 HGGVKVVGFDFGNYKYDLFSTLLIDNAKYPAIAMVVLLIIMCLYLNSIIIAFCGLLSIIF 235 Query: 427 SLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQE 486 +L AYF Y V ++FFPF+N++ +V ++GIGADDAF+Y IW+ K Sbjct: 236 ALVDAYFIYKIVLGINFFPFLNVVTLVFLVGIGADDAFVYYDIWRQTKK----------- 284 Query: 487 NGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFA 546 + E L + +T+R++ +++ +T++TT+ AF+AS S I +I CF +FA Sbjct: 285 --------AHPNEDCLT-LTWKTLRYAALSMLVTSMTTSAAFFASVSSKITSIKCFGIFA 335 Query: 547 GTAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVNEM----WENIRIVLNRFT 602 G ++L +++M+TW P V + + + + + V + E + ++ Sbjct: 336 GISILTCYLMMITWFPAVVLLHERWIRRRTIDQMPKAEPTVQSIRDGEQEASAVKPTKWL 395 Query: 603 IICVTKFHIAF---VVVMG-ALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFEQYEMQY 658 V K + F V+ +G +GFI V+F SP + LP SK FQ+F +S EQYEM Sbjct: 396 PNAVLKKRLYFLWIVIFIGLTIGFIC--VIFVSPKISLPSSKDFQVFASSSTLEQYEMNV 453 Query: 659 RDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSW 718 ++ + + G G + ++ +WGVK DNG+H++P G L ++ NF P+SQ W Sbjct: 454 KNNIRYAQ-----GQGWGLWVKLIWGVKPEDNGHHLNPDDLGTLTYENNFDPFAPESQKW 508 Query: 719 LLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNIDKINRSPCCETSKFPYKK 778 +L ++ Q F+ +T P E F +D + C E FPY + Sbjct: 509 MLSLSKNLRNQTFFSKTKN-YYPKTPFEMF-----------LDHAIQESCLENYTFPYPR 556 Query: 779 EVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEM 838 VF+ C K + + V + + KP A+ F + Y+ ++ M Sbjct: 557 AVFENCYKKL---------DFYNKYVL---YDENGKP---RAVSWGFATDFSYTSAFKPM 601 Query: 839 NKFFTEVEKWTQTELENAPAGMKCGWFLSD-FQFYDLQRTLASGTIVALLLSAALGFIVL 897 + F+ E+ W+ E+ AP G++ GW + + FY LQ +L++GT ++ +S A+ F+V+ Sbjct: 602 DDFWNEINSWSTKEMAKAPKGLQNGWAVCESLDFYSLQASLSAGTFSSMSISVAIAFVVM 661 Query: 898 IPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALS 957 + TLN S+ A+ ++ +T+ LV+ W+LNILES+ +S + GL++DF++HY ++ Sbjct: 662 LLTTLNIFISLYAIITIVGILAITVGSLVLLGWQLNILESIVMSVAVGLSIDFTMHYGVA 721 Query: 958 Y--TNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTV 1015 Y + + RV+Y G+ ++ + +L Y+Q+G FL+L+M Sbjct: 722 YRLSPYKDRRDIRVRYSFVHIGSAIFMAALTTFITGLLMMPAIVLVYNQLGVFLMLVMFF 781 Query: 1016 SWTYATFFLCSLLHIVG 1032 S+ YAT S+ ++G Sbjct: 782 SYIYATLAFQSMCALIG 798 >UniRef50_Q19153 Cluster: Dispatched family protein 2; n=2; Caenorhabditis|Rep: Dispatched family protein 2 - Caenorhabditis elegans Length = 936 Score = 179 bits (436), Expect = 3e-43 Identities = 164/663 (24%), Positives = 302/663 (45%), Gaps = 53/663 (7%) Query: 376 IDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFY 435 I +KN +F I D+ A + VF+C IY+RS+I T + +T S G+A+F Y Sbjct: 307 IALNMKNKVFQERIQTDSLFAAFSALLVFSCFLIYSRSIIFTCIILMVVTLSSGVAFFIY 366 Query: 436 VYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINIS 495 V + FFPF+NLLV+VI++ IGADDAF+ + ++ +++ + + + + G + I + Sbjct: 367 TVVLGIDFFPFINLLVVVILISIGADDAFLLLVYYR---REVERMSHLEYKVGSIYIPLY 423 Query: 496 SAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFV 555 + +L + L ++ HS+V++F+T+LTTA F + S + + CF V+A V VN++ Sbjct: 424 RESD-LLSRSLRLSLHHSLVSMFVTSLTTASTFLTNLSSPVIVLRCFGVYAALTVTVNYI 482 Query: 556 LMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVNEMWENIRIVLNRFTIICVTKFHIAFVV 615 L++ LP ++ + + KK + D + + E + T I ++ Sbjct: 483 LVVLILPGAIIL--SRPIRKKLSRGDEEPEKI-ESHSYFASKITETTHYFRFGIFICSLI 539 Query: 616 VMGALGFISLVVVFYSPGLHLPDSKQFQLFQTSHPFEQYEMQ-YRDKFLFERLSKDLGTG 674 + G +SL ++F +PGL P + +L S+ E ++ + F ++R Sbjct: 540 MTG----LSLFIIFQNPGLKTPQTNPTKLLVDSNIHEYFDNNVHHFNFQWQR-------S 588 Query: 675 TKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQ 734 ++ +V+GV AI + + P +K +NFS + + L F RI Sbjct: 589 ARLVKNFVFGVDAIKETSTLSPYNKP----SKNFSQAHYSLDTDKLDFYRRIVN------ 638 Query: 735 TLGPLLPNCFIESFK-MYMSRRCIDNIDKINRSPCCETSKFPYKKEVFDFCIIKA----M 789 +ES K ++ + DKI ++ S F K + CI+ A Sbjct: 639 ----------LESKKYQLVNYTHVSWADKILQA---NESCFSENKTIIHECILSASVRNK 685 Query: 790 ESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWT 849 ++Q P + + GP + K + + S + + FF E+E+ + Sbjct: 686 NLIHQFPDDFSVIPGDGPFIDQDLK---VVGYFISIPSNQKLQVDTEMIGSFFQEIEE-S 741 Query: 850 QTELENAPA-GMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSV 908 +++NA + + C +FYD+ L S + ++ +S + IV+I T S+ Sbjct: 742 CKQIKNATSDSVLCLSSTEITRFYDIVSQLRSSSFTSVAISLGICLIVIIACTRVIKLSI 801 Query: 909 CALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNAS-GNKSA 967 + + F T+A L++ W+L+++ES + + GL+ D++LHY ++ + S Sbjct: 802 ISSVIIFFVILWTVASLILLGWQLSVVESTILIITIGLSFDYTLHYVVAIRDTKCVPASE 861 Query: 968 RVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSL 1027 ++ AG LL S + QIG LV++ S A+ L S Sbjct: 862 KLTSAHSTAGIACVFGSLTLFLAGCPLLFSQTASFYQIGTMLVILGITSLFGASIVLPSF 921 Query: 1028 LHI 1030 L + Sbjct: 922 LMV 924 >UniRef50_A7SM68 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 487 Score = 157 bits (380), Expect = 2e-36 Identities = 92/294 (31%), Positives = 159/294 (54%), Gaps = 33/294 (11%) Query: 249 CCPVWSLPNYIALISGKDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAAC-------DL 301 CCP WS+ NY+A +SG+ +C ++ EDVK+ +T LK CA +F+N TL C Sbjct: 42 CCPSWSVGNYVASLSGRQTCQDVTDEDVKEVMTRLKSCAKFFNNGTLKENCWDYKNSLPY 101 Query: 302 DHC-NVPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPL-PRSD-TVLPYY 358 +C N+P C + NAV+ + +YL D E + Q+ + T F P R + + YY Sbjct: 102 PYCVNIPLACVKDNAVFIIFYYLTDKEFLG--TDMQEHLSYTQAFTPRWHRGEYSKAIYY 159 Query: 359 KKLENSNMSYDNLVIPAIDFG-LKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILT 417 + LE M + + DF LK ++F+ ++ D ++ + + +W YT S+++T Sbjct: 160 RYLEGKTMEDGPVRLVGTDFYFLKFSMFNTKLLADIIYPSIALMIILIIMWFYTESILIT 219 Query: 418 LFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQL 477 + L ++ +L +AYF + + L+FFPF+N+ ++ ++GIGADDAF++ +W +Q Sbjct: 220 ILLAVSVVSALILAYFVNMIILRLNFFPFLNITTLIFLVGIGADDAFVFCDVW----RQS 275 Query: 478 IKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYAS 531 +D+ G + L + T+RH+ ++F+T+ TTA AF A+ Sbjct: 276 KRDH---------------PGAS-LKTVTYTTLRHASTSMFVTSFTTAAAFVAN 313 >UniRef50_O76372 Cluster: Abnormal chemotaxis protein 14; n=2; Caenorhabditis|Rep: Abnormal chemotaxis protein 14 - Caenorhabditis elegans Length = 917 Score = 120 bits (290), Expect = 2e-25 Identities = 186/864 (21%), Positives = 337/864 (39%), Gaps = 123/864 (14%) Query: 194 PISDYAHLVITNTDN-SSLLSYKNVERLCKFQSXXXXXXXXXXXXXCQRTTHSEDICCPV 252 P+ D+ I N ++ + K +++LC+ QS R + Sbjct: 126 PLMDHLSQFILEVPNYDAIFNLKFLDKLCQMQSNISKPLSRFDAFTPYRN---------I 176 Query: 253 WSLPNYIALISG--KDSCVNLNKEDVKKAVTILKKCAGYFHNFTLMAACDLDHCN----- 305 WS+ N A IS + +C L++ D+K + C Y T + C + C Sbjct: 177 WSVANMFACISPNLRVNCTELDESDIKIVRKTIDNCWKYR---TQIFECRDEKCQGQCAT 233 Query: 306 ---VPKYCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVLPYY-KKL 361 +P+ C+ +Y+L + L+ + + F+ NT FLP+ T+ Y + + Sbjct: 234 CRELPENCSSQ-IMYDLFYRLLPKQ-----RDDTPFLVNT--FLPV---FTLTGYITQNI 282 Query: 362 ENSNMSYDNLVIPAID------FGLKNALFDIW-------IIEDTWLIALGGIFVFACVW 408 + + YD+L ID F LK L D+ + D+ L L V V Sbjct: 283 PVNVIIYDDLETSIIDYSKKNKFHLKGLLMDVKRDRLLAAALRDSMLALLAAGLVMIVVA 342 Query: 409 IYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVK 468 ++++SL+ + + +L + VY FP +NL+ V+++ IG+DDAF Sbjct: 343 VHSQSLLYAFVVI--LLLALSVVGALGVYSLFTDEFPLLNLVTFVLLIAIGSDDAF---- 396 Query: 469 IWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAF 528 L+K N N T L H+ T+F+T +T V F Sbjct: 397 --------LLKSNFPKHLN-------EDTFHTFL--------SHTSFTMFLTCFSTIVPF 433 Query: 529 YASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVN 588 + + S + CF +FAG V+ N+ +++++LP + I Y F + Sbjct: 434 FINITSNVIVFRCFGLFAGVTVIFNYFMVVSFLPAFLLIQ----YRHFDCFTGFKFPYRS 489 Query: 589 EMWENIRIVLNRFTIICVTKFHIAFVVVMGALGFISLVVVFYSPGLHLPDSKQFQLFQTS 648 + + ++L ++ ++ + ++ + A+G ++ GLHLP+ QLF + Sbjct: 490 VLSHLLYVLLPH--VLVQGRYVLISLLSIVAIGGAAITY----QGLHLPEYNPLQLFTSD 543 Query: 649 HPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNHMDPASKGHLVFDENF 708 + E Y+ F F L + R VWGV+ I + + + L D F Sbjct: 544 NLHEWYDNNAERNFEFVSAKIAL----PLTSRLVWGVEPIYSLSTFRANATSPLRSDPIF 599 Query: 709 SISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNIDKINRSPC 768 S+ L F + PF P F++ Y R C Sbjct: 600 SLKTAGDVRKLARFLGTARQLPFVNHQ-PKFWPERFLDWSDKYPCARGF---------LC 649 Query: 769 CETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESI 828 C + + DFC+ + L + + P F V + ++ Sbjct: 650 CNMTNPLFSDSYLDFCLRNSTSFLATSYNDT-------PIFDNKT------FAFVGYTAM 696 Query: 829 VPYSLSYSEMNKFFTE-VEKWTQTELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALL 887 +P SL Y+ K ++ E T+ +N + W +S + +DL ++ + +++ Sbjct: 697 LPTSLKYNHRFKQLSKSFEMLEMTKPDNGWWAPEW-WLMSTW--FDLLSSIVQDCLSSVV 753 Query: 888 LSAA-LGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGL 946 S + I +V + +IF+S+ + +L W L +LE+V + GL Sbjct: 754 GSLVFVAIFAFIQLKFQAFAAVVTIACVIFTSSAIVTLL---GWVLGVLEAVILVLVVGL 810 Query: 947 AVDFSLHYALSYTNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIG 1006 + D++LHY + G R++ AG +L + + Q+G Sbjct: 811 SFDYTLHYGAALPE-HGCAEHRIREATSKGVGPVTLAAFTSFLAGASMLPALTHAFYQVG 869 Query: 1007 AFLVLIMTVSWTYATFFLCSLLHI 1030 FLV+I SWT++TFF +L + Sbjct: 870 VFLVVISITSWTFSTFFYLPMLSL 893 Score = 37.1 bits (82), Expect = 2.7 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Query: 5 YSRFIVRHSYLVLFTVSILSIVLTVIPLILHELPSFSDPIVGFETRGTTLAHRFIAWENL 64 YSR + RH L L +++ V+ + + + +GF+T+ T L+ +AW + Sbjct: 9 YSRSLYRHPTLFLILPVLITTVIPFGLIWFFPIKLSQNAEIGFDTKDTDLSGPRLAWSRI 68 Query: 65 NDETRPSKRLAV-NPKEIEDQIR 86 S R+A NP+ I+ ++ Sbjct: 69 QPSLMFSNRIAFSNPRPIDTDVQ 91 >UniRef50_A4RS32 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 716 Score = 110 bits (265), Expect = 2e-22 Identities = 155/653 (23%), Positives = 268/653 (41%), Gaps = 74/653 (11%) Query: 405 ACVWIY----TRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGA 460 A VW+Y TRSL + I S IA Y ++F + + + L I I LGIGA Sbjct: 71 AAVWLYMAFNTRSLFIATCGMFEILVSFPIALLIYRFIFRIPYVGNIQALSIFICLGIGA 130 Query: 461 DDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFIT 520 DD F+Y ++ + + G+ + +++ T R S IF+T Sbjct: 131 DDVFVYFDAFRQSATE------------------AEVGDALFDRLMYSTDRAS-KAIFVT 171 Query: 521 TLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFL 580 + TT AF A+ S I + F + + T + V FV+ + P ++ + Y + T+ Sbjct: 172 SFTTTGAFLATAWSPITPLAAFGIVSATMIAVLFVVNVLLFPAALVLF--ARYFENMTWR 229 Query: 581 DLV--HKNVNEMWENIRIVLNRFTIICVTKFHIA----FV--VVMGALGFISLVVVFYSP 632 + K +NE L R F+ FV V +GA + +V + Sbjct: 230 QFLPASKEINESEIVESKELGRVERFFHGPFYQTLRRPFVRFVTIGAFTAMFIVAARFCV 289 Query: 633 GLHLPDSKQFQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGN 692 L P SK + + + H +Q+ RD+ F R DL + WG+ +D + Sbjct: 290 RLETP-SKIERWYSSKHLVQQFSD--RDQTAFLRSDDDLVVAVDV----FWGLLGVDMSS 342 Query: 693 --HMDPASKGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTL--GPLLPN--CFIE 746 D AS+G L DE+F +S SQ +L C ++ + G L + CF+E Sbjct: 343 VSQWDLASRGRLQLDESFDVSAEVSQVHILNSCLTLRHASCSSRGCRDGRLTRDVDCFME 402 Query: 747 SFKMYMSRRCIDNIDKINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAG 806 +F+ Y+ +N P S + E+++F ++ S Y + F P Sbjct: 403 AFRDYVGE---ENF------PVPRDS---FLDELWEFRS-SSVGSRY-AHQIGFRPN--- 445 Query: 807 PKFLRSAKPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFL 866 +++ P + + V +S + + S E E + E AP G+K G Sbjct: 446 ----KNSGEPELFFVKVSTKSTLMHQAPASVSRGVHDEFEGLIRNLNEVAPDGVKSGSQT 501 Query: 867 S--DFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLN-FVTSVCALT-AMIFSSTVTI 922 + + + +Q TL T + + + F+VL +T N V S+C+++ A + S + I Sbjct: 502 AYVAWTWMRMQETLVDNTFQGISICFCMAFVVLCISTGNVLVASICSVSVAGVVVSVLGI 561 Query: 923 AVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNASG---NKSARVKYXXXXXXXX 979 V + +W L I E++A GL+VD+ +H +Y A ++ R +Y Sbjct: 562 GVYRVMHWSLGIRETIAAVILIGLSVDYGVHLGNAYVEAPAAMKSRGDRTQYALATMGVS 621 Query: 980 XXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 +G L L +++ + + S +A F+ LL +G Sbjct: 622 IVASAVTTVISGSILWLCTLQFFAKFAFLITTTIASSLVWALVFISLLLITLG 674 >UniRef50_A4RT66 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 1011 Score = 101 bits (241), Expect = 1e-19 Identities = 93/428 (21%), Positives = 176/428 (41%), Gaps = 29/428 (6%) Query: 634 LHLPDSKQFQLFQTSHPFEQYEMQYRDKFLFERLSKDLGTGTKMPLRWVWGVKAIDNGNH 693 L P + QL H F ++ R F + S + TK+ +WGV DNG+H Sbjct: 605 LSTPRDSEVQLLPDDHMFTKFSFLRRSGF---KSSTESQVWTKV----LWGVTPSDNGDH 657 Query: 694 MDPASKGHLVFDENFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMS 753 +PAS+ + +D +F +S +Q+WL FC+ K C+ E F+ ++ Sbjct: 658 FNPASRASIEWDTSFDLSPTANQNWLKTFCSDTKSNMANDNAA-----YCWFEYFETWLG 712 Query: 754 RRCIDNIDKINRSPCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSA 813 + C P + F C+ + Q P M F S Sbjct: 713 SAG-------GPTECGGYKFIPVPQANFYSCVKYYAD---QNPSVQMMSRPLSNAFYTSN 762 Query: 814 KPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSD-FQFY 872 + + V+F + V ++ ++ K + E + ++ APAG+K G+ SD + + Sbjct: 763 GQTRMKIMSVQFATNVLWTAPTEDLEKVWQTWENYFAAKMATAPAGLKNGFQTSDAWAWM 822 Query: 873 DLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKL 932 D + G +A + A+ + + +T N + ++ +L ++ VT+A +V W L Sbjct: 823 DTVAQMRDGAYIAAGTTLAIAAVTTMISTQNVIITLYSLLCILTILVVTVAGVVSMGWNL 882 Query: 933 NILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVKYXXXXXXXXXXXXXXXXGF--- 989 LE + + GL+VD+ +H +Y +A+ ++ + F Sbjct: 883 GFLEGICLVILIGLSVDYVVHIGHAYAHAARHEGVSRRECARSALSVMGFPVLGAAFTTL 942 Query: 990 -AGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSSIKESPSR--ERKP 1046 A + LL++ ++ +++ G +VL S + LL G + +R RK Sbjct: 943 CAALALLQAVIVFFTKFGTIVVLSAVFSSIVSVVLFIGLLAAAGPVNGMGDVTRLCGRKA 1002 Query: 1047 VSRVNSVS 1054 +S+ S++ Sbjct: 1003 LSKSKSIA 1010 Score = 73.3 bits (172), Expect = 3e-11 Identities = 50/193 (25%), Positives = 94/193 (48%), Gaps = 19/193 (9%) Query: 367 SYDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITF 426 SY N+ +K+A D + +D L + +W++ S++LT+ + Sbjct: 329 SYFNVYYDTASSDVKDAYVDEQLFKDLALAVSAISIIIILMWVHMGSVLLTVGGIVQVLL 388 Query: 427 SLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQE 486 + A FF + L FFPF+N + + ++ GIGADD F+ M K +Q+ Sbjct: 389 AFPSAIFFTKTLCQLDFFPFLNFIGLFVIAGIGADDCFV------MYDK--------FQQ 434 Query: 487 NGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFA 546 + + ++A E +++ S +F+T++TTA AFY++ + I I F++F Sbjct: 435 SKCRCVPGANATE-----VMKRAYWDSAWAMFLTSMTTAAAFYSNAIIPIAPIRVFAIFM 489 Query: 547 GTAVLVNFVLMMT 559 GT V+ +++ +T Sbjct: 490 GTMVIFDYLYDIT 502 >UniRef50_Q010M7 Cluster: Predicted membrane protein; n=3; Eukaryota|Rep: Predicted membrane protein - Ostreococcus tauri Length = 1449 Score = 85.4 bits (202), Expect = 8e-15 Identities = 54/174 (31%), Positives = 82/174 (47%), Gaps = 18/174 (10%) Query: 389 IIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMN 448 +I D LIA+G V +++T S+ +T I S AY FY YV L + Sbjct: 326 MIHDAKLIAVGLALVVVYTYVHTGSVFITFCGILEILVSFPAAYAFYAYVLKLKTISVLQ 385 Query: 449 LLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEE 508 L I I+LGIG DD F++ ++ K + G+T+ + L Sbjct: 386 FLAIFIILGIGVDDVFVFYDSFEDASKA-----------------VGIRGDTLEAR-LNY 427 Query: 509 TMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLP 562 H+ + +T++T+ AF A+ S IPA+ F VF VLVN+ L++TW P Sbjct: 428 AYDHAGRAMLVTSMTSGAAFAANIASAIPAVQVFGVFIAVMVLVNYFLVITWFP 481 Score = 46.4 bits (105), Expect = 0.004 Identities = 24/81 (29%), Positives = 45/81 (55%) Query: 881 GTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAI 940 GT+ ++ +S A T + + AL +M+ + IA+LV K I+E++++ Sbjct: 1191 GTVGSIGVSLAFAVFATFIFTGDIFVAAMALFSMVAIISAVIAILVYLGVKFGIVEAISL 1250 Query: 941 STSAGLAVDFSLHYALSYTNA 961 + G++VDFSLH A ++T + Sbjct: 1251 TILVGISVDFSLHLAEAFTRS 1271 >UniRef50_A4S176 Cluster: RND family transporter: Dispatched segment polarity protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: RND family transporter: Dispatched segment polarity protein - Ostreococcus lucimarinus CCE9901 Length = 1154 Score = 68.5 bits (160), Expect = 9e-10 Identities = 55/191 (28%), Positives = 96/191 (50%), Gaps = 18/191 (9%) Query: 382 NALFDIWIIEDTWLIALGGIFV-FACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFN 440 N++ D + +D + A+G + V A + ++TRSL L + +I + + + Y V+ Sbjct: 443 NSMLDDRLAKDC-VFAVGSLCVTVAFIALHTRSLSLAICSMISIIGATLLTHATYYEVYR 501 Query: 441 LHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGET 500 +F +++ I + +GIGADD F+ W Q +NV +E+ LD + Sbjct: 502 REWFGIIHIAGIFLSIGIGADDVFVIYDHW-----QASANNVEEKES--LDATLEER--- 551 Query: 501 ILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTW 560 ++ T+RHS +I IT+ TTA AF +S S IP + F F T ++ +L+ Sbjct: 552 -----MQWTLRHSAFSISITSFTTAAAFASSIPSSIPPVRLFGTFMATQIIF-LLLVSIV 605 Query: 561 LPISVFIVDVK 571 + SV I++ K Sbjct: 606 VTSSVLILNEK 616 Score = 65.7 bits (153), Expect = 7e-09 Identities = 71/339 (20%), Positives = 128/339 (37%), Gaps = 17/339 (5%) Query: 707 NFSISDPKSQSWLLGFCARIKGQPFYQQTLGPLLPNCFIESFKMYMSRRCIDNIDKINRS 766 ++ SD SQ WLL FCA ++ + + P NC+I +++ K Sbjct: 827 SYDFSDEDSQIWLLEFCAELRSMR--DRIVSPTTVNCWIYDLDVWL---------KDGGL 875 Query: 767 PCCETSKFPYKKEVFDFCIIKAMESLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFE 826 P ++ F + + + F+ R +A + Sbjct: 876 LGAHIDGLPIARQDFRYAVRTFANHVNTYGLLRFIRNRDDCDKYRLGDDLCVAYSAITVP 935 Query: 827 SIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSD-FQFYDLQRTLASGTIVA 885 + + E+ K E W ++ P + + SD + D L S + Sbjct: 936 TSARRVSTADEIRKAHDFWETWFAAKISTGPPETRGAFQSSDTWVLADTVDELKSAASLT 995 Query: 886 LLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVT-IAVLVINNWKLNILESVAISTSA 944 ++ S L F+VL TL+ V A T I S V +A + + W+L I+ESV + Sbjct: 996 VVYSLVLAFMVLFLCTLS-VKIAAAATFCIASVVVYFVAFMALRGWRLGIIESVCVQIIV 1054 Query: 945 GLAVDFSLHYALSYT---NASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLP 1001 GL++D+ H A++Y N K R A LL ++ Sbjct: 1055 GLSIDYISHIAVAYVSTHNQPMTKDERSLSALRIVGGAITAGWFSSIAAAACLLGCTIVF 1114 Query: 1002 YSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSSIKESP 1040 +++ F+V+ +T S+ +A L +L +G + ++ P Sbjct: 1115 FTKFATFIVVTLTASFIHAVVVLPVVLAALGPAYVQPPP 1153 >UniRef50_A7RP60 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1098 Score = 66.9 bits (156), Expect = 3e-09 Identities = 40/160 (25%), Positives = 75/160 (46%), Gaps = 1/160 (0%) Query: 874 LQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLN 933 +Q LAS + +L+S L +L T N++ + A + + + + + WKL Sbjct: 881 VQEVLASTAVRGILMSLGLAIGLLTLMTTNWIVGLMAGATIACITVGVVGFIPLVGWKLG 940 Query: 934 ILESVAISTSAGLAVDFSLHYALSYTNASGN-KSARVKYXXXXXXXXXXXXXXXXGFAGV 992 +LES+ ++ GLAVD+ +H A Y + + + + + A V Sbjct: 941 VLESLNLTLVVGLAVDYVVHLADGYVRSHNHFRGDKTRDALGSVGISVLSGACTTLGASV 1000 Query: 993 FLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 F+L + ++ + Q G F+ + +S +YA F +LL +VG Sbjct: 1001 FMLAAKIVFFFQFGIFMFCTIGLSISYALLFFTTLLALVG 1040 Score = 62.9 bits (146), Expect = 5e-08 Identities = 46/187 (24%), Positives = 84/187 (44%), Gaps = 23/187 (12%) Query: 389 IIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMN 448 +I D L F+F + T+S+ +T + +I A F Y + + + + Sbjct: 276 VIYDLLLAGASFTFIFLFMLFQTQSIWITSWAVFSILSCFFGANFVYRMILDCRYIGIFH 335 Query: 449 LLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEE 508 +L + I+LGIGADD F+++ W+ ++ + L L Sbjct: 336 VLSVFIILGIGADDVFVFLDTWRGSDQRAFPN---------------------LAAKLSF 374 Query: 509 TMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIV 568 R + +FIT++TT VAF S S + ++ F +F+ V VN+ ++T+ P ++ Sbjct: 375 VYRRAASAMFITSVTTMVAFTTSVFSPLLGVSTFGIFSALLVFVNYCSVITFFP--TVVI 432 Query: 569 DVKLYAK 575 +LY K Sbjct: 433 TYELYWK 439 >UniRef50_A7RP59 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1016 Score = 66.9 bits (156), Expect = 3e-09 Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 20/177 (11%) Query: 389 IIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMN 448 +I D L+ +F+F + T+SL +T + +I S A Y V + + + Sbjct: 258 VIGDLLLVVASFLFIFIFMLCQTQSLWITSWGLFSIVSSFFGANLIYRIVLDYRYVGVFH 317 Query: 449 LLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEE 508 +L + I+ GIGADD F+++ W+ ++++ LD L Sbjct: 318 VLSVFIIAGIGADDVFVFLDTWRAA-------KSTHRDHSFLD-------------KLSF 357 Query: 509 TMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISV 565 T RH+ + IT+ TT VAF ++ +S + A++ F VF+ V+VN++ ++ + P V Sbjct: 358 TYRHAAGAMLITSTTTFVAFMSNALSPLLAVSSFGVFSALIVMVNYLSVIIFFPTVV 414 Score = 64.9 bits (151), Expect = 1e-08 Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 3/160 (1%) Query: 875 QRTLASGTIVALLLSAALGFIVLIPATLNF-VTSVCALTAMIFSSTVTIAVLVINNWKLN 933 + L +L+S L F +L+ N+ V +C LT + V I + + WKL Sbjct: 806 KEVLVENATRGILISLCLTFPILLLMLGNWAVALLCILTISCITVGV-IGFITMFGWKLG 864 Query: 934 ILESVAISTSAGLAVDFSLHYALSYTNA-SGNKSARVKYXXXXXXXXXXXXXXXXGFAGV 992 +LES+ ++ GLAVD+ +H A Y N S + RVK+ A + Sbjct: 865 VLESLNLTLVVGLAVDYVVHLADCYVNCPSACRLDRVKFTLGHVGISVISGACTTLGAAM 924 Query: 993 FLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVG 1032 F+ + +L + Q GAF+ + +S ++ F LL +VG Sbjct: 925 FMFAAKILFFFQFGAFIFCTIGLSLLFSLFLFTILLGLVG 964 >UniRef50_Q013Q5 Cluster: Predicted membrane protein; n=2; Ostreococcus|Rep: Predicted membrane protein - Ostreococcus tauri Length = 1164 Score = 57.2 bits (132), Expect = 2e-06 Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 17/170 (10%) Query: 384 LFDIWIIEDTWLIALGGIFV-FACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLH 442 L D + +D+ L A+G + V + I TRS+ L L +I + + + Y ++ Sbjct: 102 LVDQRLAKDS-LFAIGSLCVTMGLITITTRSVCLALGGIISIAGTFVLTHVTYFELYRCD 160 Query: 443 FFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETIL 502 +F +++ I + +GIGADD +I W+ E+ V + E + Sbjct: 161 WFGIIHIAGIFLAIGIGADDIYIIADHWR--------------ESSVA-VGEKETRERTM 205 Query: 503 VQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLV 552 +E TM HS+ +I IT+ TT+ AF ++ S I + F ++ T +++ Sbjct: 206 QARMEWTMSHSLFSIGITSFTTSAAFASNIPSSIEPVRLFGIYMATEIIL 255 Score = 55.2 bits (127), Expect = 9e-06 Identities = 44/224 (19%), Positives = 91/224 (40%), Gaps = 7/224 (3%) Query: 818 IAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSD-FQFYDLQR 876 +A V + +P + +MNK + W ++ + P + S + D + Sbjct: 532 VAYSAVSMVTSIPKISTPEKMNKGYEFWANWFDAKIASGPPETVDAFQCSQAWMVADTVQ 591 Query: 877 TLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILE 936 + S T+ +++LS L F VL T +F+ S A + +A + + W+ I+E Sbjct: 592 EIKSATLRSIVLSIVLAFGVLFLCTRSFLCSSLATFCIASVIVYFVAFMSLKGWRFGIIE 651 Query: 937 SVAISTSAGLAVDFSLHYALSY----TNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGV 992 +V + G+++D+ H ++Y K V+ A Sbjct: 652 AVCVQIIVGISIDYPCHVCIAYIATRRRLMSRKERSVRALRTVGTAVASGWLSSVASAAC 711 Query: 993 FLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSSI 1036 LL ++ +++ +F+++ +T S+ A L L ++ R I Sbjct: 712 -LLGCVIVFFTKFASFIIVTLTSSFILAVIVL-PLARVIARQVI 753 >UniRef50_Q5VTU9 Cluster: Patched domain-containing protein 2; n=24; Tetrapoda|Rep: Patched domain-containing protein 2 - Homo sapiens (Human) Length = 1438 Score = 56.0 bits (129), Expect = 5e-06 Identities = 46/196 (23%), Positives = 90/196 (45%), Gaps = 24/196 (12%) Query: 392 DTWLIALGGIFVFACVWIYTR-SLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLL 450 D L + + A V+I T S+ L+ F A+I S +A F Y VF + + +N + Sbjct: 508 DMLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGV 567 Query: 451 VIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETM 510 +++GIG DD F+++ ++ ++D + + + +AG+ Sbjct: 568 AAFVIVGIGVDDVFVFINTYRQATH--LEDPQLRMIH-----TVQTAGK----------- 609 Query: 511 RHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDV 570 F T+LTTA A+ A+ S IPA++ F +F V ++ ++ +P ++ + + Sbjct: 610 -----ATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVSCCWLAVLVTMPAALGLWSL 664 Query: 571 KLYAKKKTFLDLVHKN 586 L + + H+N Sbjct: 665 YLAPLESSCQTSCHQN 680 Score = 35.9 bits (79), Expect = 6.2 Identities = 17/86 (19%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 883 IVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSST----VTIAVLVINNWKLNILESV 938 + + L L ++ + A F T + L ++ S + + ++ + W++ +E++ Sbjct: 1226 VQSALCGLVLSLLICVAAVAVFTTHILLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAI 1285 Query: 939 AISTSAGLAVDFSLHYALSYTNASGN 964 ++S G +VD+ +H Y A N Sbjct: 1286 SLSILVGSSVDYCVHLVEGYLLAGEN 1311 >UniRef50_UPI00015A7054 Cluster: Patched domain-containing protein 2; n=2; Danio rerio|Rep: Patched domain-containing protein 2 - Danio rerio Length = 833 Score = 52.8 bits (121), Expect = 5e-05 Identities = 46/178 (25%), Positives = 81/178 (45%), Gaps = 31/178 (17%) Query: 392 DTWLIALGGIFVFACVWIYTR-SLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLL 450 D L G + V++ T S+ LT F A+I S +A F Y VF + + +N + Sbjct: 414 DMLLALFSGGCITVLVYVLTSFSVFLTFFGLASIGLSCLVALFLYHVVFGVKYLGILNGV 473 Query: 451 VIVIVLGI-GADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEET 509 +++GI G DD F+++ ++ S T +Q + T Sbjct: 474 AAFVIIGIGGVDDVFVFISTFR-----------------------QSVHLTCPMQRMIST 510 Query: 510 MRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFI 567 M+ + F+T+ TTA A+ A+ S IPA++ F +F ++ ++ WL +SV + Sbjct: 511 MKTAGRATFLTSFTTAAAYAANTFSQIPAVHDFGLF------MSLIVSCCWLWVSVLM 562 >UniRef50_A7RNK5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1507 Score = 51.6 bits (118), Expect = 1e-04 Identities = 36/136 (26%), Positives = 72/136 (52%), Gaps = 21/136 (15%) Query: 424 ITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVV 483 + S+G++ F F + + P ++L ++ LGIG DD F+ V+ W +N+ Sbjct: 894 VGLSIGVS-FGMSSAFGVFYGPVHSVLPFLL-LGIGVDDMFVIVQAW---------NNLT 942 Query: 484 YQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFS 543 +E+ +++ E I + T++H+ +I IT+LT +AF + +P + F Sbjct: 943 PEEHKTKEVH-----ERIAL-----TLQHAGCSITITSLTDFLAFLIGASTVLPGLQSFC 992 Query: 544 VFAGTAVLVNFVLMMT 559 ++AG +L++F+L +T Sbjct: 993 IYAGLGILIDFILQIT 1008 >UniRef50_A2DYD9 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 815 Score = 51.6 bits (118), Expect = 1e-04 Identities = 48/216 (22%), Positives = 86/216 (39%), Gaps = 23/216 (10%) Query: 368 YDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFS 427 Y PA FGL N I++ W + +F F I RS +L + F Sbjct: 302 YGTHAYPAFVFGL-NFKIAALILQQVWWLIGAFLFTFVFAVIVQRSFFTSLLGVIGVFFP 360 Query: 428 LGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQEN 487 + A F + ++++ + ++ GIGAD FI +++K + VY N Sbjct: 361 IPCALCSLRMFFGITHVDVIDVIGLFLICGIGADCVFIIFELFK-------QSRNVYGTN 413 Query: 488 GVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAG 547 L L ++ ++ + + T+AV+F A S + +N F +F Sbjct: 414 NKLR--------------LAYALQRGLIALSTSITTSAVSFLALSSSGVRIMNFFGIFCF 459 Query: 548 TAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLV 583 +L F++ TW + + + K + K LD + Sbjct: 460 MLLLFTFIVTFTWY-LGIVSIWAKRWEKHNDMLDTI 494 >UniRef50_UPI0000E477D4 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 1422 Score = 51.2 bits (117), Expect = 2e-04 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Query: 401 IFVFACVWIYTR-SLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIG 459 + +F ++++T SL LT+ +I +S +AYF Y F + +N++ + +++GIG Sbjct: 504 VAIFVLLFVFTSFSLWLTICGLLSIIYSFCLAYFCYHVFFGIEALGLLNVVSVFVIIGIG 563 Query: 460 ADDAFIYVKIWKMIGKQLIKD 480 DD F++V ++ + I D Sbjct: 564 VDDVFVFVNTFRQLQIPAIYD 584 >UniRef50_Q1JXP1 Cluster: Exporters of the RND superfamily-like precursor; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Exporters of the RND superfamily-like precursor - Desulfuromonas acetoxidans DSM 684 Length = 1002 Score = 50.8 bits (116), Expect = 2e-04 Identities = 46/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%) Query: 886 LLLSAALGFIV-LIPATLNFVTSVCALTAMIFSSTVTIAVLV----INNWKLNILESVAI 940 +L S A F+V L+ L F + + AMI TVTI+++ + ++ +V Sbjct: 836 MLSSLAGSFVVVLVMMMLLFRSVIWGALAMI-PLTVTISLIYGLIGVAGKDYDMPVAVLS 894 Query: 941 STSAGLAVDFSLHY-----ALSYTNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLL 995 S + GL+VDF++H+ L N +S +V + GF LL Sbjct: 895 SLTLGLSVDFAIHFLQRARELYRQNGDWTESCKVMFKEPARAITRNAITISVGFTP--LL 952 Query: 996 RSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGR 1033 + L+PY +G FL IM VSW + L +LL ++ R Sbjct: 953 LAPLVPYKTVGFFLATIMAVSWLASLIILPALLTLLQR 990 >UniRef50_Q7RHN1 Cluster: Drosophila melanogaster CG11212 gene product; n=4; Plasmodium (Vinckeia)|Rep: Drosophila melanogaster CG11212 gene product - Plasmodium yoelii yoelii Length = 1310 Score = 50.0 bits (114), Expect = 4e-04 Identities = 26/72 (36%), Positives = 45/72 (62%), Gaps = 1/72 (1%) Query: 506 LEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISV 565 ++ +R S V I +TTLT +AF S VS AI FS+F +A+ +++L++T L +S+ Sbjct: 582 IQMCLRDSAVAITVTTLTNVIAFLISAVSPFYAIYSFSLFTTSALFFSYILVITIL-VSI 640 Query: 566 FIVDVKLYAKKK 577 ++ +L +KK Sbjct: 641 LCIEARLEKEKK 652 >UniRef50_O15118 Cluster: Niemann-Pick C1 protein precursor; n=39; Chordata|Rep: Niemann-Pick C1 protein precursor - Homo sapiens (Human) Length = 1278 Score = 50.0 bits (114), Expect = 4e-04 Identities = 27/80 (33%), Positives = 49/80 (61%), Gaps = 2/80 (2%) Query: 498 GETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLM 557 GET L Q L + ++F+++ + VAF+ +S +PA++ FS+FAG AV ++F+L Sbjct: 717 GET-LDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQ 775 Query: 558 MTWLPISVFIVDVKLYAKKK 577 +T +S+ +D+K K + Sbjct: 776 ITCF-VSLLGLDIKRQEKNR 794 >UniRef50_Q7PXL5 Cluster: ENSANGP00000011713; n=2; Culicidae|Rep: ENSANGP00000011713 - Anopheles gambiae str. PEST Length = 627 Score = 49.6 bits (113), Expect = 5e-04 Identities = 32/129 (24%), Positives = 71/129 (55%), Gaps = 8/129 (6%) Query: 510 MRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVD 569 ++H+ +I +T+LT VAF ++ IP++ F ++A V + FV ++T+ +++F +D Sbjct: 148 LQHAGASITVTSLTDIVAFIVGSITVIPSLQSFCIYAAAGVFMMFVFVITFF-VAIFTLD 206 Query: 570 -VKLYAKKKTF-LDLVH-KNVNEMWENIRIVLNRFTIICVTKFHIAFVVVMGALGFISLV 626 +++ +++ +F L +VH + +W + ++RF +KF + +G + I V Sbjct: 207 ELRIASRRNSFLLWVVHDEKSTSLWCEYNL-MHRFINALYSKF---LLTTVGKVLVILAV 262 Query: 627 VVFYSPGLH 635 V+ +H Sbjct: 263 VLMTGVNVH 271 >UniRef50_Q4UAK5 Cluster: Putative uncharacterized protein; n=1; Theileria annulata|Rep: Putative uncharacterized protein - Theileria annulata Length = 1166 Score = 49.2 bits (112), Expect = 6e-04 Identities = 74/327 (22%), Positives = 131/327 (40%), Gaps = 36/327 (11%) Query: 309 YCTQHNAVYNLLFYLIDSEAFSPLNNAQKFVKNTMLFLPLPRSDTVLPYYKKLENSNMSY 368 Y T N N +F++I+S + +NN KN + L L + L N N+ Sbjct: 82 YSTIFNIFINNIFFIINSNYSNKINNFNNLNKNNLNNLNLNNLN--------LNNLNIGE 133 Query: 369 DNL--VIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLF-LFAAIT 425 N +I I F L N IW+I D LI F C IY L + L +F + Sbjct: 134 SNFNGIISIIIFILINIHLIIWLILDKKLIGN-----FNC--IYDNILEINLINIFEIFS 186 Query: 426 FSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQ 485 LGI +FF + F + + L++I+I+ F + WK + I + Sbjct: 187 LILGILFFFSILFFIIKLYSISYLIIIIIL--------FSLLSRWKFLS---IHSSNGGS 235 Query: 486 ENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVS-YIPAINCFSV 544 NG N +++ T + +S T T Y +YV+ Y+ N + Sbjct: 236 SNGAC-TNRTNSNNTYSNKSYSSNNTYSKDTYSKDTKVRNT--YGTYVNKYMIDKNNYFP 292 Query: 545 FAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVNEMWENIRIVLNRFTII 604 T V ++++ L + + + + F++ ++ N N + N N F + Sbjct: 293 IVQTLVTCLIIIILIILLLIILFTNNNFITRNTNFINFINTNTN--FNNTNTNFN-FINL 349 Query: 605 CVTKFHIAFVVVMGALGFISLVVVFYS 631 + F I ++++ + FI + F++ Sbjct: 350 KIKLFIIIILLIILLIIFILFLYYFFT 376 >UniRef50_UPI00015B5B2F Cluster: PREDICTED: similar to putative hedgehog receptor; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative hedgehog receptor - Nasonia vitripennis Length = 1791 Score = 48.8 bits (111), Expect = 8e-04 Identities = 59/252 (23%), Positives = 108/252 (42%), Gaps = 24/252 (9%) Query: 847 KWTQTELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVT 906 K+ + L N P+G+ F+ Q+ DL+ L +VAL+ S + I+L+ A + Sbjct: 1435 KFEEKGLPNFPSGIP---FIFWEQYMDLRSCLGIALLVALIASIIVVGILLLNAWAAILV 1491 Query: 907 SVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKS 966 L ++ + ++ + KL+ + +V + S G++V F++H LS+ G++ Sbjct: 1492 GA-VLAGVVLQ---LLGIMGLCGIKLSAVPAVLLVVSVGISVHFTVHICLSFVTCVGSRD 1547 Query: 967 ARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLI--MTVSWTYATFFL 1024 RV+ A V +L + + FLVL+ + V FF Sbjct: 1548 RRVRLALEHMYAPVVHGALTTLLA-VLMLAFSEFEFIVRYFFLVLVCLIGVGLVNGLFFF 1606 Query: 1025 CSLLHIVGRSS---IKESPSR------ERKPVSRVNSVSSGVPNLESHELEHL---ADSN 1072 LL ++G S+ E P R P+ R +S P H++E+ A+ + Sbjct: 1607 PILLSLIGPSAEVIPNEHPDRISTPTPPSSPIVRRSSSKPPAPPRRPHKIENARLHAEPS 1666 Query: 1073 RTNVTHSQSPSS 1084 T +T + P+S Sbjct: 1667 LTTIT--EEPNS 1676 >UniRef50_UPI0000DB6CB9 Cluster: PREDICTED: similar to PaTched Related family member (ptr-19); n=1; Apis mellifera|Rep: PREDICTED: similar to PaTched Related family member (ptr-19) - Apis mellifera Length = 881 Score = 48.4 bits (110), Expect = 0.001 Identities = 45/207 (21%), Positives = 93/207 (44%), Gaps = 37/207 (17%) Query: 454 IVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHS 513 ++L +G DD F+ + WK + Q + N ++ + + + AG I+ Sbjct: 379 LLLALGVDDNFLIMASWKEVHAQKLNRNKPLEKR--IALMLGHAGSAII----------- 425 Query: 514 IVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLY 573 IT+LT VAF + +P++ + ++A VL+ F+ +T+ ++ F +D + Sbjct: 426 -----ITSLTDVVAFIIGASTILPSLQSYCIYAAFGVLLTFLFQITFY-VAFFSIDARRI 479 Query: 574 AKKKTFLDLVHKNVNEMWENIRIV-LNRFTIICVTKFHIAFVVVMGALGFISLVVVFYSP 632 K+ +N+++ NI + L + TI+ +T +G +G + L ++ P Sbjct: 480 ENKRL--------INKIYSNIILTKLGKITIVLIT----IVTASVGLVGILQL-QQWFDP 526 Query: 633 GLHLPD----SKQFQLFQTSHPFEQYE 655 +P+ SK + + +P YE Sbjct: 527 TWFIPNHSYLSKYINVHRAEYPDRGYE 553 >UniRef50_A7QPC0 Cluster: Chromosome chr18 scaffold_137, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr18 scaffold_137, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 1263 Score = 48.4 bits (110), Expect = 0.001 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 8/169 (4%) Query: 870 QFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINN 929 Q+ D+ RT ++ L ++ FIV + T + +S L + + V+ I N Sbjct: 1082 QYLDIWRT----ALINLAIAIGAVFIVCLVITCSLWSSAIILLVLAMIVVDLMGVMAILN 1137 Query: 930 WKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVKYXXXXXXXXXXXXXXXXGF 989 +LN L V + + G+AV+F +H +++ +SG+++ R+K Sbjct: 1138 IQLNALSVVNLVMAVGIAVEFCVHITHAFSVSSGDRNQRMKEALGTMGASVFSGITLTKL 1197 Query: 990 AGVFLL---RSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSS 1035 GV +L R+ + +L L++ + + + FL +L + G S Sbjct: 1198 VGVIVLCFSRTEVFVVYYFQMYLALVL-LGFLHGLVFLPVVLSMCGPPS 1245 >UniRef50_A7SH24 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 881 Score = 48.0 bits (109), Expect = 0.001 Identities = 35/129 (27%), Positives = 70/129 (54%), Gaps = 26/129 (20%) Query: 445 PFMNLLVIV--IVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETIL 502 PF++L+ ++ ++LGIG DD FI V D + Q+N + + Sbjct: 313 PFISLVGVLPFLILGIGIDDMFILV------------DELDRQDN-----------KLSV 349 Query: 503 VQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLP 562 + ++ MRHS +T+ +TT+T VAF S + P+I F ++A +V +++++++T+ Sbjct: 350 IDTIKMVMRHSGMTVTMTTVTDLVAFAVSTSTAFPSIRYFCIYAALSVTLSYLMIITYF- 408 Query: 563 ISVFIVDVK 571 +++ DV+ Sbjct: 409 VAIATFDVR 417 Score = 36.3 bits (80), Expect = 4.7 Identities = 27/113 (23%), Positives = 52/113 (46%), Gaps = 4/113 (3%) Query: 852 ELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCAL 911 +LE +K F F++ + S TI L ++AA ++ P L+ V L Sbjct: 638 DLEENDKSLKAYPISRFFIFFEQYSLIQSETIRNLAIAAAAVLLITWPFLLSI--RVTLL 695 Query: 912 TAMIFSSTVTIAVLVINNW--KLNILESVAISTSAGLAVDFSLHYALSYTNAS 962 + FS+ + +++ W LN + + + + G +VD+S H A ++ +S Sbjct: 696 VFLGFSALIVELFALMSVWDVSLNAISMINLVMAIGFSVDYSAHIAHAFVTSS 748 >UniRef50_A7BSE2 Cluster: Integral membrane protein; n=1; Beggiatoa sp. PS|Rep: Integral membrane protein - Beggiatoa sp. PS Length = 809 Score = 47.6 bits (108), Expect = 0.002 Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Query: 504 QILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPI 563 + ++E++R ++ IF+T+LTTA+ F + +P + V + F+L +T+LP Sbjct: 352 EAIKESLRVNLQPIFLTSLTTAIGFLSLNFGEVPPFHDLGNIVAVGVTIAFILSVTFLPA 411 Query: 564 SVFIVDVKLYAKKKTFLDLVH 584 + I+ VK KK D +H Sbjct: 412 MMAILPVKTQPKKS---DAIH 429 >UniRef50_Q6L1D3 Cluster: Transporter involved in lipid transport; n=1; Picrophilus torridus|Rep: Transporter involved in lipid transport - Picrophilus torridus Length = 891 Score = 47.6 bits (108), Expect = 0.002 Identities = 25/90 (27%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Query: 395 LIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVI 454 LI + I +F ++ L L + + ++I SL I Y+ + Y+ NL F+ + V + Sbjct: 728 LIIVIYIILFILLYSALTPLRLIIIVISSIVSSLSITYYIFKYLMNLPVIIFLPIFVSIT 787 Query: 455 VLGIGAD-DAFIYVKIWKMIGKQLIKDNVV 483 +L +G D D F+ ++ + I K++ +DN + Sbjct: 788 LLAVGLDYDIFMVTRVIENIDKKIDQDNAI 817 >UniRef50_O83769 Cluster: Antibiotic transport protein, putative; n=1; Treponema pallidum|Rep: Antibiotic transport protein, putative - Treponema pallidum Length = 888 Score = 47.2 bits (107), Expect = 0.003 Identities = 40/182 (21%), Positives = 72/182 (39%), Gaps = 6/182 (3%) Query: 854 ENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTA 913 EN P + + S L + +++L+ S + FI++ + + Sbjct: 702 ENFPQDVHAEFGGSVLVEQSLNDLVVQSQLISLVFSLCVVFIIIAVHYRSLFAGIIGTLP 761 Query: 914 MIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNA----SGNKSARV 969 + S V V+ KLNI ++ S+G+ VD+++HY +Y A G Sbjct: 762 LGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGIGVDYTIHYLAAYRRAWKECGGKDFLTQ 821 Query: 970 KYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLH 1029 + GFA + L + N+L + G +VL M S + L +LL+ Sbjct: 822 TFYGSGRAILFNVLSVGSGFAVLMLSKFNVL--ADFGLLMVLAMLTSSVASLTLLPTLLN 879 Query: 1030 IV 1031 +V Sbjct: 880 VV 881 >UniRef50_UPI000038E024 Cluster: hypothetical protein Faci_03001404; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03001404 - Ferroplasma acidarmanus fer1 Length = 912 Score = 46.8 bits (106), Expect = 0.003 Identities = 32/110 (29%), Positives = 57/110 (51%), Gaps = 12/110 (10%) Query: 395 LIALGGIFVFACVWIYTRSLI----LTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLL 450 ++ L GI +F + I S + L L + AA+ +L + Y + Y+ +L F+ L Sbjct: 738 MVPLLGITIFIILLIQLASALTPVRLILMVMAAVMLALSLTYIIFYYLLHLPVIIFLPLF 797 Query: 451 VIVIVLGIGAD-DAFIYVKIWKMIGK-----QLIKDNVVYQENGVLDINI 494 V + +L +G D D F+ K+ + I K + +KD++V ENG + I + Sbjct: 798 VFITLLAVGLDYDIFMITKVQENISKGMNTAEAVKDSIV--ENGGVIITL 845 >UniRef50_Q21L50 Cluster: Patched; n=2; Gammaproteobacteria|Rep: Patched - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 778 Score = 46.8 bits (106), Expect = 0.003 Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Query: 496 SAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFV 555 +AG+T Q + T+ + IF T LTTAV FYA V+ + + F++ AG A L+ F+ Sbjct: 306 AAGQTPQ-QAAQSTVVNLFYPIFFTCLTTAVGFYALSVTELSPVRQFALLAGIAPLIIFI 364 Query: 556 LMMTWLP 562 L T LP Sbjct: 365 LTNTLLP 371 >UniRef50_Q1NUP1 Cluster: Exporter, RND superfamily precursor; n=2; delta proteobacterium MLMS-1|Rep: Exporter, RND superfamily precursor - delta proteobacterium MLMS-1 Length = 883 Score = 46.8 bits (106), Expect = 0.003 Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 11/182 (6%) Query: 857 PAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIF 916 P+ ++ W S + Q + G + A L S + F+++ TL F + + L AMI Sbjct: 696 PSQLRHDWAGSTYINVVWQEKMVYGMLTAFLGSFIVVFLMM---TLLFRSPLWGLLAMI- 751 Query: 917 SSTVTIAVLV----INNWKLNILESVAISTSAGLAVDFSLHYALSYTNAS---GNKSARV 969 TVT+A + I ++ +V S + GLAVDF++H+ +A G+ +A Sbjct: 752 PMTVTVAFIYGLIGIVGKDYDMPVAVLSSLTLGLAVDFAIHFLQRSRDAHRRLGSWAAAR 811 Query: 970 KYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLH 1029 K + LL + L+PY +G FL IM VS + L + + Sbjct: 812 KEVFAEPARAISRNAIVVAVGFMPLLAAPLMPYKTVGFFLAAIMAVSGVATVYMLPAAIR 871 Query: 1030 IV 1031 ++ Sbjct: 872 LL 873 >UniRef50_Q1K3Y2 Cluster: Patched; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Patched - Desulfuromonas acetoxidans DSM 684 Length = 761 Score = 46.8 bits (106), Expect = 0.003 Identities = 20/67 (29%), Positives = 36/67 (53%) Query: 499 ETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMM 558 + + + T+ H V F+T+ TTA+ F + VS +P I F + A ++ F+L M Sbjct: 303 DAAVTDTIRRTLVHLAVPCFLTSFTTAIGFASLAVSQVPPIRHFGLAAAGGMMAEFLLTM 362 Query: 559 TWLPISV 565 T +P+ + Sbjct: 363 TLIPVGI 369 >UniRef50_A2DYE0 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 177 Score = 46.4 bits (105), Expect = 0.004 Identities = 26/127 (20%), Positives = 57/127 (44%), Gaps = 2/127 (1%) Query: 886 LLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAG 945 +++S A+G +V+ +TL ++ + +M + + + ++ I W + E++ IS +AG Sbjct: 15 VVISFAIGAVVIFCSTLRIGYTLMVVYSMSCTCLLIMGIMYITGWSIGTNEAIMISIAAG 74 Query: 946 LAVDFSLHYALSYTNASGNKS--ARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYS 1003 DF + L+ + N+S +++Y A FL +L + Sbjct: 75 FCADFIIQPMLAIAHDKSNRSLFGKIQYSLVSFATPVSSALVTTLVAACFLYPCAILLFP 134 Query: 1004 QIGAFLV 1010 +FL+ Sbjct: 135 PFASFLL 141 >UniRef50_UPI00015B5B0C Cluster: PREDICTED: similar to conserved hypothetical protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to conserved hypothetical protein - Nasonia vitripennis Length = 957 Score = 46.0 bits (104), Expect = 0.006 Identities = 39/174 (22%), Positives = 80/174 (45%), Gaps = 30/174 (17%) Query: 408 WIYTRSLILTLFLFA---AITFSLGIAYFFYVYVFNLHF-FPFMNLLVIVIVLGIGADDA 463 W+ R + ++ LF A ++G+ F V +H PFM ++G+G DD Sbjct: 364 WVEWRFWLTSVALFCIGGAFAVAIGLCSLFGVPYGPVHTSLPFM-------LMGLGVDDT 416 Query: 464 FIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLT 523 F+ + W+ + + +++N + L + + + H+ I +T+LT Sbjct: 417 FVMMAAWEEV--------ISHEKNR----------DKPLPERVALALSHAGAAISVTSLT 458 Query: 524 TAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKK 577 VAF + +P+++ F ++A V V F+L +T+ ++ F +D + K+ Sbjct: 459 DVVAFVIGASTILPSLHSFCIYAAVGVFVTFILQVTFF-VAFFTLDCQRVENKR 511 >UniRef50_Q5QWJ5 Cluster: Predicted exporter, RND superfamily; n=4; Gammaproteobacteria|Rep: Predicted exporter, RND superfamily - Idiomarina loihiensis Length = 838 Score = 45.6 bits (103), Expect = 0.008 Identities = 19/86 (22%), Positives = 48/86 (55%), Gaps = 3/86 (3%) Query: 506 LEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISV 565 +++ +RH + T++T+++ FY+ ++ IP + F F G+ +L+ F++ + ++P Sbjct: 304 IKDVLRHLFTPMLFTSITSSIGFYSLMLTPIPPVQVFGAFVGSGILLAFLITVLFVP--A 361 Query: 566 FIVDVKLYAKKKTFLDLVHKNVNEMW 591 +I +K + ++F + H + W Sbjct: 362 YICALK-PSTLESFTQVTHDEHKQGW 386 Score = 41.1 bits (92), Expect = 0.16 Identities = 41/203 (20%), Positives = 85/203 (41%), Gaps = 11/203 (5%) Query: 839 NKFFTEVEKWTQTELEN--APAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIV 896 N+ T+V K + +++ PA + W + Q + G + +L+ + + FI+ Sbjct: 631 NQHVTQVVKAVDSYIQDNPLPANTEMDWAGKAYLNVVWQEAMVEGMLDSLISAFVVVFIM 690 Query: 897 LIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYAL 956 ++ + V V A+ + + ++ ++ +V S + GL+VDF++H+ + Sbjct: 691 MVLLFRSVVFGVLAMLPLSLTIAFIYGLIGWVGKDYDMPIAVLSSLTLGLSVDFAIHF-I 749 Query: 957 SYTNASGNKSAR------VKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLV 1010 T A+ ++ V + GF LL + L+PY +G FL Sbjct: 750 ERTRATFKQTGNWKDTLVVMFDEPARAISRNAIVIAIGFTP--LLFAPLVPYITVGVFLA 807 Query: 1011 LIMTVSWTYATFFLCSLLHIVGR 1033 IM +S L +++ + R Sbjct: 808 SIMAISAIVTLIMLPAVMTVFSR 830 >UniRef50_A5APM6 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 1050 Score = 45.6 bits (103), Expect = 0.008 Identities = 27/101 (26%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Query: 870 QFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINN 929 Q+ D+ RT ++ L ++ FIV + T + +S L + + V+ I N Sbjct: 896 QYLDIWRT----ALINLAIAIGAVFIVCLVITCSLWSSAIILLVLAMIVVDLMGVMAILN 951 Query: 930 WKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVK 970 +LN L V + + G+AV+F +H +++ +SG+++ R+K Sbjct: 952 IQLNALSVVNLVMAVGIAVEFCVHITHAFSVSSGDRNQRMK 992 >UniRef50_Q5DTE5 Cluster: Putative uncharacterized protein ptr-17; n=4; Caenorhabditis|Rep: Putative uncharacterized protein ptr-17 - Caenorhabditis elegans Length = 936 Score = 45.6 bits (103), Expect = 0.008 Identities = 20/54 (37%), Positives = 36/54 (66%) Query: 506 LEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 +E+ MRH+ V+I IT+LT A+AF ++ +PA+ F ++ A+L F+ ++T Sbjct: 399 IEKAMRHAAVSISITSLTDALAFLIGSIAPLPAVIYFCYYSSAAILFIFLYVLT 452 >UniRef50_Q8I266 Cluster: Patched family protein, putative; n=3; Plasmodium|Rep: Patched family protein, putative - Plasmodium falciparum (isolate 3D7) Length = 1470 Score = 44.8 bits (101), Expect = 0.013 Identities = 21/72 (29%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Query: 506 LEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISV 565 ++ ++ S + I +TTLT +AF S +S +I FS+F +++ +++++T+L +S Sbjct: 592 IQMCLKDSALAITVTTLTNIIAFLISAISPFYSICAFSLFTASSLFFGYLMVLTFL-LSF 650 Query: 566 FIVDVKLYAKKK 577 ++ KL KK+ Sbjct: 651 LCIEAKLEKKKR 662 >UniRef50_O16307 Cluster: Patched related family protein 16; n=2; Caenorhabditis|Rep: Patched related family protein 16 - Caenorhabditis elegans Length = 881 Score = 44.0 bits (99), Expect = 0.023 Identities = 40/182 (21%), Positives = 87/182 (47%), Gaps = 36/182 (19%) Query: 401 IFVFACV----WIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIV--I 454 IF+FA ++++ ++++ + A + G A+ F +++F FPF ++ +++ + Sbjct: 196 IFIFATNSREHFVFSHNVVMAILGIAGPLMATGTAFGF-LFLFG---FPFNSITLVMPFL 251 Query: 455 VLGIGADDAFIYVKIWKMIGK-QLIKDNVVYQENGVLDINISSAGETILVQILEETMRHS 513 ++G+G DD FI + + K + ++D + ETM + Sbjct: 252 IIGVGCDDVFIIIHAMRKTDKSESLEDRIA------------------------ETMEEA 287 Query: 514 IVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLY 573 +I +T+ T ++F + PAI+ F ++ AV V+FV +T+ ++V + + K Sbjct: 288 GPSITVTSATNCLSFAIGIATPTPAISLFCLYTCVAVAVDFVYQLTFF-VAVLVYEEKRL 346 Query: 574 AK 575 K Sbjct: 347 MK 348 >UniRef50_Q17GY7 Cluster: Patched 1, putative; n=11; Endopterygota|Rep: Patched 1, putative - Aedes aegypti (Yellowfever mosquito) Length = 1116 Score = 43.6 bits (98), Expect = 0.031 Identities = 46/207 (22%), Positives = 84/207 (40%), Gaps = 15/207 (7%) Query: 853 LENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALT 912 L N P+G+ FL Q+ +L+ L AL+ + L ++L+ + + +T Sbjct: 862 LPNYPSGIP---FLFWEQYMNLRPCLLKAIGCALVAAFCLVALLLLSVWASILIVFSIVT 918 Query: 913 AMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVKYX 972 +I + V+++ L+ + +V + S GL V F++H +L + A GN+ R+K Sbjct: 919 MLI----QLLGVMILLGINLSAIPAVILIASIGLGVCFTVHVSLGFITAIGNRDRRIKLA 974 Query: 973 XXXXXXXXXXXXXXXGFAGVFLLRSNL-LPYSQIGAFLVLIMTVSWTYATFFLCSLLHIV 1031 A + L S+ L+ ++ + FF LL +V Sbjct: 975 LEHSLAPVIHAVMTSILAVLMLSTSSFEFVVRHFFWLLLSVLVIGAVNGLFFFPILLSLV 1034 Query: 1032 GRSSIKESPSRERKPVSRVNSVSSGVP 1058 G P E P+ N +S+ P Sbjct: 1035 G-------PGAEIIPLQYANRISTPSP 1054 >UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1277 Score = 42.7 bits (96), Expect = 0.054 Identities = 19/56 (33%), Positives = 38/56 (67%), Gaps = 1/56 (1%) Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVK 571 ++ +++L+ +VAF +S +PA+ FS++A AV V+F+L +TW +++ +D K Sbjct: 726 SMLLSSLSESVAFGFGAMSDMPAVKVFSLYASFAVAVDFILQITWF-VALMSLDAK 780 >UniRef50_UPI0000D573E9 Cluster: PREDICTED: similar to CG5722-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG5722-PA - Tribolium castaneum Length = 1210 Score = 42.3 bits (95), Expect = 0.071 Identities = 35/152 (23%), Positives = 73/152 (48%), Gaps = 6/152 (3%) Query: 502 LVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWL 561 L + + ETM ++ +T+ + F +S +PA+N F+++A A+ NF+L +T Sbjct: 526 LEEEIGETMAKVGPSMLLTSCSEIFCFAIGALSTMPAVNTFAIYATFAIFFNFLLQITAF 585 Query: 562 PISVFIVDVKLYAKKKT---FLDLVHKNVNEMWENIRIVLNRFTII-CVTKFHIAFVVVM 617 +++F +D+K Y + F + + ++ I + + I + F + VV++ Sbjct: 586 -VALFTLDLKRYRANRMEIFFCEKAKTSPEDIGPGIVYKIWKTNITPLIMNFPVRCVVLL 644 Query: 618 GALGFISLVVVFYSPGLHLPDSKQFQLFQTSH 649 L ++ V + P L L +Q + + SH Sbjct: 645 LFLIWL-CVSIAVMPSLELGLDQQLSMPEDSH 675 >UniRef50_A7BSN4 Cluster: Exporter of the RND superfamily; n=3; Gammaproteobacteria|Rep: Exporter of the RND superfamily - Beggiatoa sp. PS Length = 760 Score = 42.3 bits (95), Expect = 0.071 Identities = 33/154 (21%), Positives = 70/154 (45%), Gaps = 6/154 (3%) Query: 420 LFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLG-IGADDAFIYVKIWKMIGKQLI 478 +F I LG+ + F F++++V + + G +G +I I Sbjct: 228 MFLVIIVLLGLLLRSFSGTFTTVLIIFLSIIVTMGIAGWLGITLTPPSATAPTIILTLAI 287 Query: 479 KDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPA 538 D+V + + ++ + + E I+ E++R + IF+T+LTTA+ F + S +P Sbjct: 288 ADSVHFLVTMLYEMRVRNKWEAII-----ESLRINFQAIFLTSLTTAIGFLSLNASDVPP 342 Query: 539 INCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKL 572 V + F+L +++LP + ++ V++ Sbjct: 343 FRDLGNIVAIGVTIAFILSVSFLPAMMAVLPVRI 376 >UniRef50_Q23E28 Cluster: Patched family protein; n=1; Tetrahymena thermophila SB210|Rep: Patched family protein - Tetrahymena thermophila SB210 Length = 1207 Score = 42.3 bits (95), Expect = 0.071 Identities = 38/166 (22%), Positives = 68/166 (40%), Gaps = 9/166 (5%) Query: 839 NKFFTEVEKWTQTELENAP--AGMKCGWFLS-DFQFYDLQRTLASGTIVALLLSAALGFI 895 +K F + + T+ ++NA G K + S + +YD + + I LLL+ ++ Sbjct: 949 SKDFIDTFEQTRQAVDNASEFTGDKKAFAYSLIYAYYDQYTQIRAIAIQNLLLAVGAVYL 1008 Query: 896 VLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNW------KLNILESVAISTSAGLAVD 949 + + AL + + V V+N+ ++N + V + TS GL V+ Sbjct: 1009 AINLLKNGMSALIVALNVFFITFNLIGIVWVLNSTISGFQIEINAVSVVNLITSVGLGVE 1068 Query: 950 FSLHYALSYTNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLL 995 F +H +SY N GN+ +V F GV +L Sbjct: 1069 FCVHLVISYMNTPGNREQKVINAVKQMGSNILVGIASTKFIGVIVL 1114 >UniRef50_Q9K6B3 Cluster: Cation efflux system; n=1; Bacillus halodurans|Rep: Cation efflux system - Bacillus halodurans Length = 1093 Score = 41.9 bits (94), Expect = 0.094 Identities = 25/73 (34%), Positives = 36/73 (49%) Query: 880 SGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVA 939 + +VAL+ A + +VL NF T + A+ FS VT A L N LNIL Sbjct: 329 NNVLVALIAGATMAMVVLFLFLRNFKTPLIIGIAIPFSVIVTFAFLYFTNVSLNILSLGG 388 Query: 940 ISTSAGLAVDFSL 952 ++ G+ VD S+ Sbjct: 389 LALGIGMLVDNSI 401 >UniRef50_Q28P83 Cluster: Exporters of the RND superfamily-like protein; n=1; Jannaschia sp. CCS1|Rep: Exporters of the RND superfamily-like protein - Jannaschia sp. (strain CCS1) Length = 697 Score = 41.9 bits (94), Expect = 0.094 Identities = 37/151 (24%), Positives = 69/151 (45%), Gaps = 8/151 (5%) Query: 891 ALGFIVLIPATLNFVTSVCALTAMIFSSTVTIA---VLVINNWKLNILESVAISTSAGLA 947 AL I L+ A L+ + AL A S+ +A VL ++ + + ++A++ + G+A Sbjct: 550 ALAAISLVVA-LSQRSIALALLATAISALPMMAIEGVLYLSGRGMTMTAAIALTVAFGIA 608 Query: 948 VDFSLHYALSYTNASGNKSARVKYXXXXXX--XXXXXXXXXXGFAGVFLLRSNLLPYSQI 1005 VD ++HY + ++G K R+ GF L + +P Q Sbjct: 609 VDNTIHYLNRWRRSNGPKGTRLGEALGHAGPPMVASTLIMTLGFGATLLSATASMP--QF 666 Query: 1006 GAFLVLIMTVSWTYATFFLCSLLHIVGRSSI 1036 G F++ + ++ A +FL +L+ +V R I Sbjct: 667 GVFVISALWMALIAALWFLPALIRLVRRKEI 697 >UniRef50_A5K9U0 Cluster: Patched family protein, putative; n=1; Plasmodium vivax|Rep: Patched family protein, putative - Plasmodium vivax Length = 1478 Score = 41.9 bits (94), Expect = 0.094 Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Query: 510 MRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVD 569 ++ S + I +TTLT +AF S VS +I FS+F +++ +++++T L +S ++ Sbjct: 662 LKDSALAITVTTLTNIIAFLISSVSPFYSICSFSLFTASSLFFGYLMVLTLL-LSFLCIE 720 Query: 570 VKLYAKKK 577 KL KK+ Sbjct: 721 GKLEKKKR 728 >UniRef50_Q4RVD6 Cluster: Chromosome 15 SCAF14992, whole genome shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 15 SCAF14992, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1197 Score = 41.5 bits (93), Expect = 0.12 Identities = 25/85 (29%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Query: 886 LLLSAALGFIVLIPATLNFVTSVCALTAMIFSS-TVTI-AVLVINNWKLNILESVAISTS 943 L +S L L+ A L F + A+ + ++ TV + V+ + N KL+ + V + S Sbjct: 1044 LSISITLACTFLVCAILLFNPWIAAIIVFVLATMTVELFGVMGLINIKLSAIPVVILIAS 1103 Query: 944 AGLAVDFSLHYALSYTNASGNKSAR 968 G+ V+F++H A+ + A+GN++ R Sbjct: 1104 VGIGVEFTVHIAMGFLVATGNRNQR 1128 Score = 37.5 bits (83), Expect = 2.0 Identities = 20/74 (27%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Query: 510 MRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVD 569 +R + +I +T++ AF+ + + IPA+ FS+ A V++N V+++ P I+ Sbjct: 554 LRRTGTSIALTSINNMTAFFMAAIVPIPALRVFSLQAAIVVVLNLVMVLLIFPA---ILC 610 Query: 570 VKLYAKKKTFLDLV 583 + LY ++ LD++ Sbjct: 611 LDLYRREAKRLDIL 624 >UniRef50_A6LLS8 Cluster: MMPL domain protein precursor; n=1; Thermosipho melanesiensis BI429|Rep: MMPL domain protein precursor - Thermosipho melanesiensis BI429 Length = 861 Score = 41.1 bits (92), Expect = 0.16 Identities = 31/155 (20%), Positives = 63/155 (40%), Gaps = 3/155 (1%) Query: 894 FIVLIPATLNF---VTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDF 950 FIV++ T+ F ++ + ++ S T+ ++V+ +K+ I SV + + Sbjct: 209 FIVVLILTITFRKLTGALLPILGVVISVIWTMGLIVLFGFKITIANSVIPVALISIGTAY 268 Query: 951 SLHYALSYTNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLV 1010 S+H Y G++ R Y + LL +++ P +G F Sbjct: 269 SIHVVNKYYEEKGDRGERAIYTLRDVGMAVLLSGITTAVGFLSLLTADIKPVWVMGIFSS 328 Query: 1011 LIMTVSWTYATFFLCSLLHIVGRSSIKESPSRERK 1045 + + + A FF+ S+L+ + +I R K Sbjct: 329 VGVMLCNFIALFFVPSMLYYINPPAIFHIEKRHSK 363 >UniRef50_Q55BN1 Cluster: NPC1 protein; n=2; Dictyostelium discoideum|Rep: NPC1 protein - Dictyostelium discoideum AX4 Length = 1342 Score = 41.1 bits (92), Expect = 0.16 Identities = 34/173 (19%), Positives = 73/173 (42%), Gaps = 4/173 (2%) Query: 869 FQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVIN 928 + ++D T+ S I+ +LL+ FIV + LN + S + ++ + ++ + Sbjct: 1153 YVYFDQYLTIKSVAIMDILLALGGVFIVCLILLLNPLVSFLVVISVGMICVDLLGIMALW 1212 Query: 929 NWKLNILESVAISTSAGLAVDFSLHYALSYTNASG--NKSARVKYXXXXXXXXXXXXXXX 986 N LN + V + + G+ ++F +H A ++ NA ++ + KY Sbjct: 1213 NISLNAVSVVNVVMAIGIGIEFCVHIASTFINAPKHFSRDQKAKYAVTEMGSSIISGIFI 1272 Query: 987 XGFAGVFLLRSNLLPYSQIGAF--LVLIMTVSWTYATFFLCSLLHIVGRSSIK 1037 GV +L + + F + I+ + + FL LL + G +++ Sbjct: 1273 TKLLGVVVLGFSTSEIFTVYYFRMYLSIVFLGGLHGLVFLPVLLSLFGTDTLQ 1325 >UniRef50_Q0AT82 Cluster: Patched family protein precursor; n=2; Proteobacteria|Rep: Patched family protein precursor - Maricaulis maris (strain MCS10) Length = 881 Score = 40.7 bits (91), Expect = 0.22 Identities = 46/210 (21%), Positives = 87/210 (41%), Gaps = 9/210 (4%) Query: 839 NKFFTEVEKWTQTELENAPAGMKCG--WFLSDFQFYDLQRTLASGTIVALLLSAALGFIV 896 N+ T V + LE+ P + WF + Q + +G ALL A I+ Sbjct: 666 NQDMTAVLRAVDHYLEDNPPPLAVDHEWFGLTYINVIWQEKMVTGMAYALLGGFAAVLIL 725 Query: 897 LIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYAL 956 + +F V ++ + + + V+ + ++ +V S S GLAVD+++H+A+ Sbjct: 726 MTALFRSFAWGVLSMIPLTVTIALIYGVIGLVGKDYDMPIAVLSSLSLGLAVDYAIHFAV 785 Query: 957 S----YTNASG-NKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIGAFLVL 1011 Y + ++AR+ + GF + LL S L+PY +G F+ Sbjct: 786 RSRQIYDDVGDWTETARLAFGEPARAIVRNVIVIGAGF--LPLLLSPLVPYQIVGVFISA 843 Query: 1012 IMTVSWTYATFFLCSLLHIVGRSSIKESPS 1041 I+ + + L +L+ + K + S Sbjct: 844 ILVSAGLASLLGLPALITLFQARLFKHTAS 873 >UniRef50_A3ZT27 Cluster: Probable integral membrane protein; n=1; Blastopirellula marina DSM 3645|Rep: Probable integral membrane protein - Blastopirellula marina DSM 3645 Length = 1091 Score = 40.7 bits (91), Expect = 0.22 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Query: 507 EETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVF 566 E + H I LTTAV + S I I F +F+ VL L+ T+LP ++ Sbjct: 397 ELAVSHGWYPCLIAALTTAVGLGSLATSNIAPIKKFGIFSAMGVLATLALLFTYLPAALQ 456 Query: 567 IVDVKLYAKKKTFLDLVHKNVNEMW-ENIRI-----VLNRFTIICVTKFHIAFVVVMGAL 620 K AKK L K+ +W EN + ++ R T++ F +AF++ L Sbjct: 457 QWPPK--AKKSKDGSLQAKSPASVWMENFALRVADFIIQRSTVVATMCF-VAFIIFGFGL 513 Query: 621 GFISLVV 627 +I V Sbjct: 514 TYIKTSV 520 >UniRef50_A2QWF9 Cluster: Remark: Niemann-Pick C precursor; n=16; Pezizomycotina|Rep: Remark: Niemann-Pick C precursor - Aspergillus niger Length = 1277 Score = 40.7 bits (91), Expect = 0.22 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Query: 480 DNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAI 539 DN+ + IN+S E I +I R +IF++ LT VAF +PA+ Sbjct: 687 DNIFLIVHEFERINVSHPDEEIDERIARAVGRIG-PSIFLSALTETVAFVMGVFVGMPAV 745 Query: 540 NCFSVFAGTAVLVNFVLMMTWLPISVFIVD 569 F+V+A AV +N VL +T ISV ++ Sbjct: 746 RNFAVYAAGAVFINAVLQITMF-ISVLALN 774 >UniRef50_Q82T82 Cluster: Acriflavin resistance protein; n=6; Proteobacteria|Rep: Acriflavin resistance protein - Nitrosomonas europaea Length = 1028 Score = 40.3 bits (90), Expect = 0.29 Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 17/166 (10%) Query: 399 GGIFVFACVWIYTRSLILTLFLFAAITFSL-GIAYFFYVYVFNLHFFPFMNLLVIVIVLG 457 G + VW++ RS+ TL + AI SL G Y F F M LL +++++G Sbjct: 340 GTLLAALIVWLFLRSVRSTLIIATAIPVSLLGAVAVMYFSGFT---FNTMTLLALLLLIG 396 Query: 458 IGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTI 517 + DDA + + + I + + +D Y + ++ + E + ++ T+ S+V I Sbjct: 397 VVVDDAIV---VLESIFRHMSRDQARYGKVDTAAASVRGSHEVVFA-VIAATL--SLVCI 450 Query: 518 FITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPI 563 F V F + F+V VL++ ++ +T P+ Sbjct: 451 F-----APVIFMDGIIGKF--FKSFAVVVTFGVLISLLVSLTLTPM 489 >UniRef50_Q1VLX1 Cluster: Putative uncharacterized protein; n=1; Psychroflexus torquis ATCC 700755|Rep: Putative uncharacterized protein - Psychroflexus torquis ATCC 700755 Length = 441 Score = 40.3 bits (90), Expect = 0.29 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 6/81 (7%) Query: 504 QILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVL---VNFVLMMTW 560 + + E+++ ++ +F+T+LTTAV IPA FS A T V+ ++F L + Sbjct: 273 EAITESLKINMTPVFLTSLTTAVGVAGVNFGKIPA---FSEMANTVVIGSAISFALSVIV 329 Query: 561 LPISVFIVDVKLYAKKKTFLD 581 LPI I+ +K + + LD Sbjct: 330 LPILFIIMPIKSHGRASIVLD 350 >UniRef50_A4M778 Cluster: Exporter of the RND superfamily-like protein; n=1; Petrotoga mobilis SJ95|Rep: Exporter of the RND superfamily-like protein - Petrotoga mobilis SJ95 Length = 802 Score = 40.3 bits (90), Expect = 0.29 Identities = 26/103 (25%), Positives = 50/103 (48%), Gaps = 1/103 (0%) Query: 851 TELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCA 910 TE+E +K G S Y+ RT+ + LS I+ A NF +++ Sbjct: 223 TEIEKT-FNIKTGLTNSYVTEYESNRTVMEDFRLTTTLSIIFITILFAFAFGNFTSTIIV 281 Query: 911 LTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLH 953 L +I S+ +T+ ++ + +LNI+ S ++ + GL + + +H Sbjct: 282 LLGLIVSTLLTMGLITLTFGELNIVTSFVMAITLGLGIAYGIH 324 Score = 37.9 bits (84), Expect = 1.5 Identities = 15/67 (22%), Positives = 36/67 (53%) Query: 506 LEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISV 565 L T + ++ +F +TT + F + +PA N ++ + +LV F++M+ ++P + Sbjct: 343 LASTYKGLLLPLFFGMITTVIVFLTLFFMGLPAFNELAIVSSMGLLVFFIIMIFFVPTLI 402 Query: 566 FIVDVKL 572 + + V + Sbjct: 403 YALKVNI 409 >UniRef50_A7RK33 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1120 Score = 40.3 bits (90), Expect = 0.29 Identities = 19/102 (18%), Positives = 53/102 (51%) Query: 869 FQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVIN 928 F F++ L +VA+++ + FIV+ + T++ ++ + + + Sbjct: 951 FTFWEQYIMLRQHLMVAIIIVLGITFIVIAGFLWSVWTAIIIDLTLVMITVQLFGFMGLA 1010 Query: 929 NWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVK 970 KL+ + +V + S G+ V+F++H +++ ++G+++ R++ Sbjct: 1011 GIKLSAVPAVTLILSVGVGVEFTVHMCMAFLTSTGDRNHRMQ 1052 Score = 35.5 bits (78), Expect = 8.2 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 515 VTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVK 571 V++ +T+ VAF + + IPA+ FS+ A V+ N++ + P ++ +DVK Sbjct: 492 VSVLLTSFNNMVAFLMAAIIPIPALRAFSIQAAVIVVFNYLAVTIVFP-AMIAIDVK 547 >UniRef50_Q92IG6 Cluster: Putative uncharacterized protein; n=9; Rickettsia|Rep: Putative uncharacterized protein - Rickettsia conorii Length = 522 Score = 39.9 bits (89), Expect = 0.38 Identities = 42/177 (23%), Positives = 73/177 (41%), Gaps = 9/177 (5%) Query: 392 DTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAY----FFYVYVFNLHFFPFM 447 DT LI L I F ++ ++++ F + T GI F Y+Y+F+ F F Sbjct: 10 DTKLIKLSAILAFIYCLLFNTAILIYKFDYYKATIFRGILELSKDFCYIYIFS--FIAFF 67 Query: 448 NLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENG-VLDINISSAGETILVQIL 506 L V +VL IG FI I K N Q G +++ E ++++ Sbjct: 68 GLSVHRLVLKIGVGFLFITSAIASYY-IYFFKINPTKQVIGSFFSTDLNEVYELTSIKLI 126 Query: 507 EETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPI 563 + + T F T + A S+V+ + + C +F + +F ++ + PI Sbjct: 127 IWII-FCLFTCFYTLKSFAAENSKSFVTKLLSTACLLIFVYNIITPSFKILKNYFPI 182 >UniRef50_Q4RWY5 Cluster: Chromosome 15 SCAF14981, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 15 SCAF14981, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1209 Score = 39.5 bits (88), Expect = 0.50 Identities = 58/263 (22%), Positives = 119/263 (45%), Gaps = 33/263 (12%) Query: 418 LFLFAAITFSLGIAYFFYV--YVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGK 475 L + ++++ SLGI +F + + + PF+ VL +G D+ FI V+ + Sbjct: 614 LIVLSSVSSSLGIFSYFGIPLTLIVIEVIPFL-------VLAVGVDNIFIIVQTLQR--D 664 Query: 476 QLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASY--V 533 + + ++Q+ G + + ++ + ET V F+ +++ + + + Sbjct: 665 ERMPHEELHQQIGRI---LGDVAPSMFLSSFSET-----VAFFLGKFNSSLKLFEAIGAL 716 Query: 534 SYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVNEMWEN 593 S +PA FS+FAG AV ++F+L ++ +S+ +D ++ LD+V ++ + Sbjct: 717 SNMPAARTFSLFAGLAVFIDFLLQISCF-VSLLGLDAS--RQEDNRLDIV--CCVKLQDR 771 Query: 594 IRIVLNRFTIICVTKFHIAFVVVMGALGFISLVVV-FYSPGLHLPDSKQFQLFQ-TSHPF 651 + + F + K + F++ F+ V V S + + D + L Q S P Sbjct: 772 EEVKKDSFLFLFFKKIYAPFLLKDWVRPFVVAVFVGMLSFSIAVVDKVEIGLDQKLSMPD 831 Query: 652 EQYEMQYRDKFLFERLSKDLGTG 674 + Y + Y F+ LS+ L TG Sbjct: 832 DSYVLDY-----FKNLSEYLHTG 849 >UniRef50_Q2AD70 Cluster: Putative uncharacterized protein; n=1; Halothermothrix orenii H 168|Rep: Putative uncharacterized protein - Halothermothrix orenii H 168 Length = 727 Score = 39.5 bits (88), Expect = 0.50 Identities = 18/82 (21%), Positives = 44/82 (53%) Query: 873 DLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKL 932 +L ++ S ++LL+ +L FI+L + SV +L + F++ + + ++ L Sbjct: 563 ELSNSMISNQTQSILLAFSLIFILLYISIRKIKPSVISLLPIAFTTLIIFGFMGLSGISL 622 Query: 933 NILESVAISTSAGLAVDFSLHY 954 N+ + S + G+ +D+++H+ Sbjct: 623 NLFTATIFSITIGVGIDYAVHF 644 >UniRef50_Q1VRS2 Cluster: Cation/multidrug efflux pump; n=2; Flavobacteriales|Rep: Cation/multidrug efflux pump - Psychroflexus torquis ATCC 700755 Length = 1037 Score = 39.5 bits (88), Expect = 0.50 Identities = 41/189 (21%), Positives = 85/189 (44%), Gaps = 19/189 (10%) Query: 450 LVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEET 509 L+I+ ++ IG + + I + L+ + +V E ++ + + + + E Sbjct: 374 LLIMGLMNIGLNQVTLAALIMAL--GMLVDNAIVVAETVIVKMEEGLSAKKAAIDACSEL 431 Query: 510 MRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTW-LPISVFIV 568 + I+TLTT++AF A Y+S N + ++V+ L+ +W + +SV Sbjct: 432 F----TPLLISTLTTSIAFLAFYLS---PTNMGDIVGPIFIIVSIALLSSWVVALSVITT 484 Query: 569 DVKLYAK-------KKTFLDLVHKNVNEMWENIRIVLNRFTIICVTKFHIAFVVVMGALG 621 L+ K K++ +D V N+ + ++NI I V+ IAF ++ +G Sbjct: 485 FCYLFLKVIPKKERKQSSIDKVINNLKKQYKNIIIKSLHHKWKVVSVIGIAF--ILSLVG 542 Query: 622 FISLVVVFY 630 F + +F+ Sbjct: 543 FTQIPFLFF 551 >UniRef50_A3ZC87 Cluster: Patched family; n=11; Campylobacter|Rep: Patched family - Campylobacter jejuni subsp. jejuni HB93-13 Length = 823 Score = 39.5 bits (88), Expect = 0.50 Identities = 32/151 (21%), Positives = 65/151 (43%), Gaps = 9/151 (5%) Query: 882 TIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAIS 941 T++ ++L+ + FI++ L F SV A+ + +V A++ + L+++ + Sbjct: 657 TLIFVILAIFILFIIVF-RDLKF--SVAAILVNVIPLSVVFALMGLLGIPLDMMSITIAA 713 Query: 942 TSAGLAVDFSLHYALSYTNASGNKSAR----VKYXXXXXXXXXXXXXXXXGFAGVFLLRS 997 + G+ VD ++HY + NKS + + GF+ ++ S Sbjct: 714 IAIGIGVDDAIHYIYRFREEIKNKSLEEAIMISHLSIGSALYYTTISIVLGFS--VMMSS 771 Query: 998 NLLPYSQIGAFLVLIMTVSWTYATFFLCSLL 1028 N +P G V +M + + + F L S L Sbjct: 772 NFIPTIYFGILTVFVMILLLSGSLFLLPSFL 802 >UniRef50_Q09614 Cluster: Protein patched homolog 1; n=3; Caenorhabditis|Rep: Protein patched homolog 1 - Caenorhabditis elegans Length = 1405 Score = 39.5 bits (88), Expect = 0.50 Identities = 33/178 (18%), Positives = 73/178 (41%), Gaps = 7/178 (3%) Query: 791 SLYQTPRELFMPGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQ 850 S + TP + + F+ +A+P + + + ++ + + E++T Sbjct: 1096 SFFPTPPKWELSKNHTENFIPAAEPLAYSQIPFYLTGLTDTAVIVDAIKDIRSVCERFTD 1155 Query: 851 TELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCA 910 L N P G+ F F++ L + A+ + F V+ N ++ Sbjct: 1156 QGLPNFPQGIA-------FTFWEQYLFLTGNLMQAISIITISVFCVISVLLFNPWAALMV 1208 Query: 911 LTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSAR 968 + + + + + KLN + +V + T+ G+ V+F++H +S+ A G +S R Sbjct: 1209 VCILGIMTCELAGFMGLVGIKLNPVSAVTLITAVGIGVEFTVHVVVSFLTALGTRSQR 1266 >UniRef50_UPI00015BCDE5 Cluster: UPI00015BCDE5 related cluster; n=1; unknown|Rep: UPI00015BCDE5 UniRef100 entry - unknown Length = 1033 Score = 39.1 bits (87), Expect = 0.66 Identities = 53/227 (23%), Positives = 99/227 (43%), Gaps = 28/227 (12%) Query: 401 IFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGA 460 IF ++I+ L +TL +I F +++ + F + L I++ LG+ Sbjct: 338 IFTSLVIFIFLADLRMTLISAMSIPFVYA-GTIGIMWILGIEF-NLVTLTAIILALGMLV 395 Query: 461 DDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFIT 520 DDA + + + I+ + V G + I E +LV + T+ SIV + Sbjct: 396 DDAIVIL--------ENIERHYVELNKGPIQAAIDGTKEVMLV-VFAGTLATSIVLL--- 443 Query: 521 TLTTAVAFYASYVSYIPAINCFSVFAGT---AVLVNFVLMMTWLPISVFIVDVKLYAKKK 577 + F SY I F AGT AVLV++++ +T++PI V I +K KK Sbjct: 444 ----PLLFVGSYPERI-----FRPLAGTLIIAVLVSYIVSITFIPI-VSIRFLKSEGKKL 493 Query: 578 TFLDLVHKNVNEMWENIRIVLNRFTIICV-TKFHIAFVVVMGALGFI 623 F ++ V ++ ++ + + + K + +++G L F+ Sbjct: 494 PFETFINNVVEKILNPLKSFYISWNALMINNKMAMRVFMILGVLLFV 540 >UniRef50_UPI0000DB7411 Cluster: PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA - Apis mellifera Length = 1238 Score = 39.1 bits (87), Expect = 0.66 Identities = 13/44 (29%), Positives = 31/44 (70%) Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 ++ +T+++ + F +S +PA+N F+++A ++L+NF+L +T Sbjct: 720 SMLLTSISECLCFLIGTLSTMPAVNTFALYASVSILINFLLQIT 763 >UniRef50_Q488G0 Cluster: Putative membrane protein; n=1; Colwellia psychrerythraea 34H|Rep: Putative membrane protein - Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibriopsychroerythus) Length = 1083 Score = 39.1 bits (87), Expect = 0.66 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Query: 504 QILEETMRHSIVTIFITTLTTAVAFYASY-VSYIPAINCFSVFAGTAVLVNFVLMMTWLP 562 +I+ ET I +TTLTT F Y +Y+P F +F V + ++ + +LP Sbjct: 315 EIIVETFEEMWRPITLTTLTTIAGFLGLYFAAYMPPFKYFGLFTAVGVAIAWLYSLVFLP 374 Query: 563 ISVFIV 568 S+ I+ Sbjct: 375 ASLAII 380 Score = 38.3 bits (85), Expect = 1.2 Identities = 44/204 (21%), Positives = 83/204 (40%), Gaps = 12/204 (5%) Query: 834 SYSEMNKFFTEVEKWTQTELENAP-AGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAAL 892 SY + ++E + + +N+ M G ++ + + L V L +S L Sbjct: 574 SYQDTKDVVLQLEAYIKENFKNSDLTAMVSGRVTVNYHWI---KDLGESHFVGLGISLFL 630 Query: 893 GFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSL 952 + V + ++ A+ ++ S + A +VI L I S+ S + GL VDF++ Sbjct: 631 VWAVSALLFGSLSAAIFAIIPVMSSILLVYATMVILKINLGIGTSMFASVAIGLGVDFAI 690 Query: 953 H------YALSYTNASGNKSARVKYXXXXXXXXXXXXXXXXGFAGVFLLRSNLLPYSQIG 1006 H TN +K+ Y GF GV L+ S ++P + G Sbjct: 691 HTIDRLKSLYRKTNGDWDKTLADFYPSTGRALFLNYLAIALGF-GV-LISSKVVPLTNFG 748 Query: 1007 AFLVLIMTVSWTYATFFLCSLLHI 1030 +V+ +T S+ + L +L+ + Sbjct: 749 TIVVIAVTTSFLASLSLLPALIKV 772 Score = 37.1 bits (82), Expect = 2.7 Identities = 44/221 (19%), Positives = 89/221 (40%), Gaps = 11/221 (4%) Query: 821 LVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELENAPAGMKCGWFLSDFQFYDLQR-TLA 879 +V E +Y E+ + K ++ A G G +L + D QR Sbjct: 173 IVAELNDEALVEATYQEILALVEKAPKTLGDKIYVAGEGAIAG-YLGSYIDADAQRLNPL 231 Query: 880 SGTIVALLLSAALGFIVLIPATL-NFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESV 938 +G I+ +++ L F + P L N + + L + + +A VI N IL + Sbjct: 232 AGLIITIII--LLAFRRVSPGILSNVIIAASVLMTLSIMALNDVAFFVITNALPVILIGI 289 Query: 939 AISTSAGLAVDFSLHYALSYTNASGNKSARV--KYXXXXXXXXXXXXXXXXGFAGVFLLR 996 +++ S + +S ++ L + + +K + + GF G++ Sbjct: 290 SVADSIHI---YSHYFELQAKSPNRDKKEIIVETFEEMWRPITLTTLTTIAGFLGLYFA- 345 Query: 997 SNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSSIK 1037 + + P+ G F + + ++W Y+ FL + L I+ S+ K Sbjct: 346 AYMPPFKYFGLFTAVGVAIAWLYSLVFLPASLAIIQPSASK 386 >UniRef50_Q30QL4 Cluster: Acriflavin resistance protein; n=1; Thiomicrospira denitrificans ATCC 33889|Rep: Acriflavin resistance protein - Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1351) Length = 1013 Score = 39.1 bits (87), Expect = 0.66 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 6/144 (4%) Query: 399 GGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYV-FNLHFFPFMNLLVIVIVLG 457 G I V+I+ R+L +TL I S+ + Y+ F L+ M L+ + + +G Sbjct: 332 GAILASIIVFIFLRNLTITLVSALTIPSSIFGTFALMDYMGFELNK---MTLIGLTLAIG 388 Query: 458 IGADDAFIYVK-IWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVT 516 I DDA + ++ I+K + + L K Y+ + I + +L + + IV Sbjct: 389 IIIDDAIVVIENIYKKMEEGLGKYEAAYEGTKEMAFTILAISAMLLAVFVPVSFMSGIVG 448 Query: 517 IFITTLTTAVAFYASYVSYIPAIN 540 F + V F A +SY A++ Sbjct: 449 KFFESFAMTVGF-AIIISYTIALS 471 >UniRef50_Q1PUR2 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 759 Score = 39.1 bits (87), Expect = 0.66 Identities = 15/64 (23%), Positives = 38/64 (59%) Query: 508 ETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFI 567 ET++H + + + ++TTA+ F + S IP + +F + ++++V+ +T +PI + Sbjct: 300 ETLQHVSIPVLMASITTAIGFASLMTSSIPPVFTTGLFMSGSAILSYVVSITLVPILLSF 359 Query: 568 VDVK 571 + ++ Sbjct: 360 IPLQ 363 >UniRef50_A0J5C4 Cluster: Exporters of the RND superfamily-like precursor; n=1; Shewanella woodyi ATCC 51908|Rep: Exporters of the RND superfamily-like precursor - Shewanella woodyi ATCC 51908 Length = 717 Score = 39.1 bits (87), Expect = 0.66 Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Query: 448 NLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILE 507 +++ I + LG+ FI I I ++ V Y + + Q L+ Sbjct: 223 SMITIFLTLGVAGWGGFILAAISGFIPVVIVSLCVAYAVHLYFGWRNALDEGADEQQALQ 282 Query: 508 ETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT-WLPIS 564 +++ +I +F LTTA+ F+ S P I F AV+VNF++ +T LPI+ Sbjct: 283 QSLSTNIKPLFWGALTTAMGFFLLVFSPSPPIQDFGKLVAFAVMVNFLVNLTILLPIA 340 >UniRef50_Q13635 Cluster: Protein patched homolog 1; n=79; Vertebrata|Rep: Protein patched homolog 1 - Homo sapiens (Human) Length = 1447 Score = 39.1 bits (87), Expect = 0.66 Identities = 19/75 (25%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Query: 508 ETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFI 567 E ++ + ++ +T+++ AF+ + + IPA+ FS+ A V+ NF +++ P I Sbjct: 539 ECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPA---I 595 Query: 568 VDVKLYAKKKTFLDL 582 + + LY ++ LD+ Sbjct: 596 LSMDLYRREDRRLDI 610 Score = 36.7 bits (81), Expect = 3.5 Identities = 23/100 (23%), Positives = 48/100 (48%) Query: 869 FQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVIN 928 F F++ L ++ + + A F+V LN T+ + + + ++ + Sbjct: 1015 FLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLI 1074 Query: 929 NWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSAR 968 KL+ + V + S G+ V+F++H AL++ A G+K+ R Sbjct: 1075 GIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRR 1114 >UniRef50_UPI0000E48D84 Cluster: PREDICTED: similar to Niemann-Pick C disease protein; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Niemann-Pick C disease protein - Strongylocentrotus purpuratus Length = 705 Score = 38.7 bits (86), Expect = 0.88 Identities = 14/56 (25%), Positives = 39/56 (69%), Gaps = 1/56 (1%) Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVK 571 ++ + L+ +++F+ ++ +PA+ F++++G +VL+NF+L +T +++ +DV+ Sbjct: 90 SMLLCGLSESISFFLGALTEMPAVRIFALYSGMSVLINFILQITAF-VALLSLDVR 144 Score = 38.7 bits (86), Expect = 0.88 Identities = 38/171 (22%), Positives = 68/171 (39%), Gaps = 8/171 (4%) Query: 869 FQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTV--TIAVLV 926 + FY+ TL IV LL++ F+V + L F S + S V T+ V+ Sbjct: 445 YVFYEQYLTLVDEAIVQLLIALVPIFVVSL-LMLGFSVSAPLIIIGCISMIVIDTMGVMY 503 Query: 927 INNWKLNILESVAISTSAGLAVDFSLHYALSYT-NASGNKSARVKYXXXXXXXXXXXXXX 985 + N + N + V + + G++V+F H S++ + R +Y Sbjct: 504 LWNIEFNAVSLVNLMMAVGMSVEFVSHITRSFSICVKEGRLERAEYALATMGSSVLSGVA 563 Query: 986 XXGFAGVFLL---RSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGR 1033 G+ +L +S L FL + + V + FL +L +G+ Sbjct: 564 MTNLPGIIVLAFAKSQLFVVFYFRMFLTITL-VGTVHGLIFLPVVLSYIGK 613 >UniRef50_UPI000065FF0C Cluster: Niemann-Pick C1-like protein 1 precursor.; n=1; Takifugu rubripes|Rep: Niemann-Pick C1-like protein 1 precursor. - Takifugu rubripes Length = 1293 Score = 38.7 bits (86), Expect = 0.88 Identities = 14/44 (31%), Positives = 31/44 (70%) Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 ++ + +L+ ++ F+ +S +PA+ F+++A A+L++FVL MT Sbjct: 743 SMLLCSLSESICFFLGALSTMPAVKSFALYAALAILLDFVLQMT 786 >UniRef50_Q9KM29 Cluster: GGDEF family protein; n=14; Vibrio cholerae|Rep: GGDEF family protein - Vibrio cholerae Length = 412 Score = 38.7 bits (86), Expect = 0.88 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 394 WLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIV 453 +L+AL GI A + + TR+ IL + ++++I S+ F+V + F LL++V Sbjct: 172 YLVALAGI---AAISVLTRNQILDVVVYSSIVLSMNAFVLFHVPYISTIMFTLSGLLILV 228 Query: 454 IVLGIGADDAF 464 ++ G + AF Sbjct: 229 YLISAGYEMAF 239 >UniRef50_A6G9V0 Cluster: Putative rRNA methylase; n=1; Plesiocystis pacifica SIR-1|Rep: Putative rRNA methylase - Plesiocystis pacifica SIR-1 Length = 891 Score = 38.7 bits (86), Expect = 0.88 Identities = 41/196 (20%), Positives = 78/196 (39%), Gaps = 6/196 (3%) Query: 869 FQFYDLQRTLASGTIVALLLSAALG-FIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVI 927 F D + LA+G ++ + + +G F++L A + ++ AL + + V++ L I Sbjct: 264 FLVIDEEGVLANG-LMRVTIGTGVGIFLLLTWAFRSLRRTIAALIPIAVGTAVSLGALRI 322 Query: 928 NNWKLNILESVAISTSAGLAVDFSLHYALSY---TNASGNKSARVKYXXXXXXXXXXXXX 984 L+ + S + GLA+DF +H Y + ++ Sbjct: 323 LFESLDPISSAFGAVLMGLAIDFPVHLIARYDEDLRKGRTRGEALRSALCKAGPGVVTGA 382 Query: 985 XXXGFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSSIKESPSRER 1044 G A + + + Y ++G + + VS + L L+ G KE+P+ R Sbjct: 383 VTTGLAFLTVATTEFTSYGELGMVTAIGLFVSLVVSLIVL-PLVFGRGDLEAKETPAEPR 441 Query: 1045 KPVSRVNSVSSGVPNL 1060 K S V ++ P L Sbjct: 442 KIASSVARIAGKAPIL 457 >UniRef50_Q5LRX2 Cluster: Membrane protein, putative; n=1; Silicibacter pomeroyi|Rep: Membrane protein, putative - Silicibacter pomeroyi Length = 1053 Score = 38.3 bits (85), Expect = 1.2 Identities = 51/239 (21%), Positives = 99/239 (41%), Gaps = 11/239 (4%) Query: 403 VFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIV-IVLGIGAD 461 VF + ++ ++ +F+ F V+V + F F+ L+V V +V+ + Sbjct: 144 VFVILVVFVAFVVFVVFVVFVAFVGFVTFVVFVVFVVFVAFVVFVVLVVFVALVVFVAFV 203 Query: 462 DAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITT 521 +Y + + + V + L + I+ + V +L +R IF+ Sbjct: 204 TLVVYAAFIEFVAFVVFIALVAFVTFVELVVLIAFIAFVVFV-VLVVLVRFVAFIIFVVL 262 Query: 522 LTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKL--YAKKKTF 579 + V + S+V+++ + F +F G VLV FV +T++ F+V V + TF Sbjct: 263 VVFVV--FVSFVTFVVFV-AFVIFVGFVVLVAFVGFVTFVAFVTFVVLVGFVAFVGFVTF 319 Query: 580 LDLVHKNVNEMWENIRIVLNRFTIICVTKF----HIAFVVVMGALGFISLVVVFYSPGL 634 + V + + T+I F +AFVV++ + F+ VV+ GL Sbjct: 320 VVFVAFVATIVDIGFVTFIALVTVIAGAGFGLVAFVAFVVLVAFVAFVVFVVLVAFVGL 378 >UniRef50_Q9W6T6 Cluster: Patched-2 protein; n=7; Euteleostomi|Rep: Patched-2 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1243 Score = 37.9 bits (84), Expect = 1.5 Identities = 18/75 (24%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Query: 508 ETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFI 567 E ++ + ++ +T+++ AF+ + + IPA+ FS+ A V+ NF +++ P I Sbjct: 528 ECLKRTGASVVLTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPA---I 584 Query: 568 VDVKLYAKKKTFLDL 582 + + LY ++ D+ Sbjct: 585 LSMDLYRREDRRFDI 599 Score = 36.3 bits (80), Expect = 4.7 Identities = 22/100 (22%), Positives = 49/100 (49%) Query: 869 FQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVIN 928 F F++ L ++++ + A F+V LN T+ + + + ++ + Sbjct: 1029 FLFWEQYVGLRHWLLLSISVVLACTFLVCAVFLLNPWTAGIIVLVLSLMTVELFGMMGLI 1088 Query: 929 NWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSAR 968 KL+ + V + S G+ V+F++H AL++ A G+++ R Sbjct: 1089 GIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDRNKR 1128 >UniRef50_Q5RJ13 Cluster: Novel protein; n=9; Euteleostomi|Rep: Novel protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 827 Score = 37.9 bits (84), Expect = 1.5 Identities = 44/204 (21%), Positives = 89/204 (43%), Gaps = 27/204 (13%) Query: 358 YKKLENSNMSYDNLVIPAIDF-GLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLIL 416 Y E ++SY V +F G +++ ++ I T+ +A+ I V +C+ + + Sbjct: 226 YTDQEKVSVSYFTSVSRQNEFEGNTDSVIPLFSI--TYALAIN-IAVLSCLRLDCVRTKV 282 Query: 417 TLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQ 476 + L ++ + + F + +F F ++LG+G DD FI + W+ K Sbjct: 283 WVALLGVVSAGMAVLASFGLLLFCGMPFAMTVGSAPFLILGVGVDDMFIMISSWQ---KT 339 Query: 477 LIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYI 536 + V ++ L E + + V+I ITTLT +AFY ++ Sbjct: 340 AVDKGVEFR--------------------LAEAYKEAGVSITITTLTDVLAFYIGLLTPF 379 Query: 537 PAINCFSVFAGTAVLVNFVLMMTW 560 ++ F ++ TA+L ++ +T+ Sbjct: 380 RSVQSFCMYTSTALLFCYLFNITF 403 >UniRef50_Q4J8A9 Cluster: Conserved membrane protein; n=2; Sulfolobus|Rep: Conserved membrane protein - Sulfolobus acidocaldarius Length = 1152 Score = 37.9 bits (84), Expect = 1.5 Identities = 20/80 (25%), Positives = 41/80 (51%), Gaps = 5/80 (6%) Query: 401 IFVFACVWIYTRSLILT----LFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVL 456 + +F +WI TRSL ++ + +A+ +L I + + F + L ++ I++ Sbjct: 990 VTMFVILWIITRSLSVSATIIFVILSAVAITLAIQRLIFSSILGFSIFAVVPLFLVAIII 1049 Query: 457 GIGAD-DAFIYVKIWKMIGK 475 GIG D + F+ +I + + K Sbjct: 1050 GIGMDYNIFLVARIHEELEK 1069 >UniRef50_UPI0000DA2841 Cluster: PREDICTED: similar to patched1; n=3; Rattus norvegicus|Rep: PREDICTED: similar to patched1 - Rattus norvegicus Length = 941 Score = 37.5 bits (83), Expect = 2.0 Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Query: 500 TILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 T L + + E +R + ++ +T++ VAF+ + + IPA+ FS+ A V NF +M Sbjct: 421 TPLPERMGECLRRTGTSVALTSINNMVAFFMAVLVPIPALRAFSLQAAIVVGCNFAAVML 480 Query: 560 WLPISVFIVDVK 571 P +V +D++ Sbjct: 481 VFP-AVLSLDLR 491 >UniRef50_Q4SP00 Cluster: Chromosome 15 SCAF14542, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 15 SCAF14542, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 816 Score = 37.5 bits (83), Expect = 2.0 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 23/108 (21%) Query: 454 IVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHS 513 ++LG+G DD FI + W+ + + D+V + L +T + Sbjct: 308 LILGVGLDDMFILISCWR---RTRVLDSVPRR--------------------LADTYGEA 344 Query: 514 IVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWL 561 V+I ITTLT A+A Y S ++ F ++AG +V ++ +T+L Sbjct: 345 GVSISITTLTNALALLVGYSSPFGSVRSFCLYAGVSVCFCYLYCVTFL 392 >UniRef50_Q7M912 Cluster: RND PUMP PROTEIN; n=1; Wolinella succinogenes|Rep: RND PUMP PROTEIN - Wolinella succinogenes Length = 1009 Score = 37.5 bits (83), Expect = 2.0 Identities = 32/151 (21%), Positives = 68/151 (45%), Gaps = 8/151 (5%) Query: 396 IALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIV 455 + LGG+ V ++ R+L +TL F ++ S I F + + L+ + + Sbjct: 328 LLLGGVLATLIVLLFLRNLTITLVAFLSLPIS--IFGTFAIMSATGQSLNLLTLIALTLS 385 Query: 456 LGIGADDAFIYVK-IWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSI 514 +GI DDA + ++ I+K + + + + + + +I + +L + + Sbjct: 386 IGIIIDDAIVVIENIYKKLEEGMERGKAALEGVREIGFSIIAISAMLLSVFVPVANMGGV 445 Query: 515 VTIFITT--LTTAVAFYASY---VSYIPAIN 540 V F T+ +T + A SY +++IP I+ Sbjct: 446 VGRFFTSFGVTVSAAIIISYIVVITFIPMIS 476 >UniRef50_Q2Y8H1 Cluster: Membrane protein, putative; n=1; Nitrosospira multiformis ATCC 25196|Rep: Membrane protein, putative - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 767 Score = 37.5 bits (83), Expect = 2.0 Identities = 19/81 (23%), Positives = 39/81 (48%) Query: 878 LASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILES 937 +++GT A + S L +L+ A + + +V L + A + +LN++ Sbjct: 150 ISTGTFNASIFSVVLVLFILVIAYRSILLTVATLITLALGVIFCGAFAAFSVAELNLISL 209 Query: 938 VAISTSAGLAVDFSLHYALSY 958 T+ GL V++++H+ L Y Sbjct: 210 AFAVTNVGLGVEYAIHFCLRY 230 >UniRef50_Q1Q069 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 916 Score = 37.5 bits (83), Expect = 2.0 Identities = 21/95 (22%), Positives = 43/95 (45%) Query: 869 FQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVIN 928 FQ YD R + G ++A + A+ F +L+ N + ++ L ++ + TI + + Sbjct: 742 FQIYDTNRLIKRGFLIAGGYTLAIIFSILLLTYRNIILTLTTLYPLLLTILWTIGFMKLF 801 Query: 929 NWKLNILESVAISTSAGLAVDFSLHYALSYTNASG 963 + N +A G+++D S+H + G Sbjct: 802 RIQPNPANVIAFPLILGISIDNSIHTMMRLNEKEG 836 >UniRef50_A7HL36 Cluster: Putative uncharacterized protein; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Putative uncharacterized protein - Fervidobacterium nodosum Rt17-B1 Length = 689 Score = 37.5 bits (83), Expect = 2.0 Identities = 21/88 (23%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Query: 883 IVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAIST 942 I +L+ + ++ F+ ++ +F ++ ++ +IF++ + + + KL I ++ S Sbjct: 528 IQSLIAALSIVFLTILIVFRDFSEALKLVSPVIFATILNFVYMALFKMKLEISTALTSSI 587 Query: 943 SAGLAVDFSLHYALSYTNASGNKSARVK 970 GLA+D+S+H Y N + N VK Sbjct: 588 IIGLAIDYSIHIGHDY-NKTKNIFTSVK 614 Score = 35.9 bits (79), Expect = 6.2 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 1/53 (1%) Query: 508 ETMRHSIVT-IFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 E R I T IF + LTTA+ F + IPA F V +L++F+L +T Sbjct: 273 EDARKQIGTPIFFSMLTTAIGFISFLFVKIPAFREFGVLVSLGLLIDFILTLT 325 >UniRef50_A4BDC7 Cluster: Predicted exporter of the RND superfamily protein; n=1; Reinekea sp. MED297|Rep: Predicted exporter of the RND superfamily protein - Reinekea sp. MED297 Length = 819 Score = 37.5 bits (83), Expect = 2.0 Identities = 16/66 (24%), Positives = 37/66 (56%) Query: 506 LEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISV 565 ++ ++ + V + +T+LTTA + ++ + I +FA V++ FVL MT +P + Sbjct: 354 MQHAIQRTAVPMLLTSLTTAGGLLSLVIADVVPIRNLGLFAAVGVMLAFVLTMTLIPALI 413 Query: 566 FIVDVK 571 ++ ++ Sbjct: 414 MLLPMR 419 >UniRef50_Q09540 Cluster: Patched family protein 2; n=1; Caenorhabditis elegans|Rep: Patched family protein 2 - Caenorhabditis elegans Length = 667 Score = 37.5 bits (83), Expect = 2.0 Identities = 27/123 (21%), Positives = 54/123 (43%), Gaps = 7/123 (5%) Query: 846 EKWTQTELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFV 905 E++T L N P G+ F F++ L + A+ + F V+ N Sbjct: 522 ERFTDQGLPNFPQGIA-------FTFWEQYLFLTGNLMQAISIITISVFCVISVLLFNPW 574 Query: 906 TSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNK 965 ++ + + + + + KLN + +V + T+ G+ V+F++H +S+ A G + Sbjct: 575 AALMVVCILGIMTCELAGFMGLVGIKLNPVSAVTLITAVGIGVEFTVHVVVSFLTALGTR 634 Query: 966 SAR 968 S R Sbjct: 635 SQR 637 >UniRef50_Q6ZU28 Cluster: Patched domain-containing protein 3; n=18; Euteleostomi|Rep: Patched domain-containing protein 3 - Homo sapiens (Human) Length = 804 Score = 37.5 bits (83), Expect = 2.0 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 23/106 (21%) Query: 454 IVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHS 513 ++LG+G DD FI + W K N+ AG+ + + + + Sbjct: 450 LILGVGVDDMFIMISAWH-------KTNL--------------AGD--IRERMSNVYSKA 486 Query: 514 IVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 V+I ITT+T +A Y +S ++ CF ++ GT +L + +T Sbjct: 487 AVSITITTITNILALYTGIMSSFRSVQCFCIYTGTTLLFCYFYNIT 532 >UniRef50_Q6ZSJ0 Cluster: CDNA FLJ45488 fis, clone BRTHA2003759; n=2; Homo sapiens|Rep: CDNA FLJ45488 fis, clone BRTHA2003759 - Homo sapiens (Human) Length = 130 Score = 37.5 bits (83), Expect = 2.0 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 9/90 (10%) Query: 401 IFVFACVWIYTRSLILT---LFLFAAITFSLGIAYFFYVYVFN-----LHFFPFMNLLVI 452 I+V+ +++Y I T L++F I L I + Y+Y+F LH F ++++ + Sbjct: 27 IYVYVYIYLYIYFYIFTYIYLYIFIYIYICLYIYLYIYLYIFTYIYIYLHIFIYLHIFIY 86 Query: 453 VIVLGIGADDAFIYVKIWKMIGKQLIKDNV 482 + + FIY+ I+ M G Q I N+ Sbjct: 87 ICICLYIFIYVFIYINIY-MRGLQNIHGNI 115 >UniRef50_Q979Z5 Cluster: Membrane protein; n=2; Thermoplasma|Rep: Membrane protein - Thermoplasma volcanium Length = 1015 Score = 37.5 bits (83), Expect = 2.0 Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 9/143 (6%) Query: 360 KLENSNMSYDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYT--RSLILT 417 K NS + Y + +D + L E+ I G IFV + + + + L Sbjct: 816 KFGNSLVFYVGGLTAGLDAAYSHTLHTF---EEMIPIITGSIFVILLIQLSSVFTPIRLI 872 Query: 418 LFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGAD-DAFIYVKIWKMIGKQ 476 L + A++ L I Y Y++ L FM + V +L +G D D F+ + + + K Sbjct: 873 LMVLASVIVGLVIIYAIVYYIYGLPIIVFMPMFTFVTLLAVGLDYDIFMITRAREGVIKG 932 Query: 477 LIKDNVV---YQENGVLDINISS 496 + + + +ENG + + + S Sbjct: 933 MSDEEAITTSIKENGGIIVTLGS 955 >UniRef50_Q4T749 Cluster: Chromosome undetermined SCAF8317, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF8317, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1132 Score = 37.1 bits (82), Expect = 2.7 Identities = 13/44 (29%), Positives = 30/44 (68%) Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 ++ + +L+ ++ F+ +S +PA+ F+++A A+L++F L MT Sbjct: 653 SMLLCSLSESICFFFGALSTMPAVKSFALYAAVAILLDFALQMT 696 >UniRef50_A6LM56 Cluster: Exporter of the RND superfamily-like protein; n=1; Thermosipho melanesiensis BI429|Rep: Exporter of the RND superfamily-like protein - Thermosipho melanesiensis BI429 Length = 692 Score = 37.1 bits (82), Expect = 2.7 Identities = 35/163 (21%), Positives = 70/163 (42%), Gaps = 10/163 (6%) Query: 797 RELFMPGVAGPKFLRSAKPPIIAALVVEFESIVPYSLSYSEMNKFFTEVEKWTQTELEN- 855 +E + V +FL + PPI +++ V + + F E+ E+E Sbjct: 456 QEGYPDNVVRVRFLLNLLPPI-------YDNFVNLKIFSGRVLIFPEEINSKVLNEIEKK 508 Query: 856 APAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMI 915 AP +K + + ++ + I +LLL+ L F+++ N S A+ + Sbjct: 509 APEDIKITG--APYIMKEMNDVIVPQQIKSLLLAVFLVFLIVFVRLKNLKESFFAILPIS 566 Query: 916 FSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSY 958 + V + I KL+I+ + S G+ +D+++H+ SY Sbjct: 567 LTLIVMFGFMGIFGIKLSIITATMGSIVVGVGIDYAIHFIESY 609 >UniRef50_A1AXL6 Cluster: Putative integral membrane protein; n=2; sulfur-oxidizing symbionts|Rep: Putative integral membrane protein - Ruthia magnifica subsp. Calyptogena magnifica Length = 793 Score = 37.1 bits (82), Expect = 2.7 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 3/103 (2%) Query: 504 QILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPI 563 Q++++T+ TTLTT VAF + +S I + F V + F+L P+ Sbjct: 346 QLIKDTLLQMFKPCLFTTLTTFVAFGSLLISGIRPVIDFGWMMSIGVTIAFMLSFLAFPM 405 Query: 564 SVFIVDVKLYAKKKTFLDL---VHKNVNEMWENIRIVLNRFTI 603 + ++ + +K KT L + + K V + ++ +VL F I Sbjct: 406 IMSLLSKEKISKHKTELSVTTSLAKFVEKFGNHLLVVLIIFVI 448 >UniRef50_Q9SVF0 Cluster: Putative uncharacterized protein F22I13.120; n=2; Arabidopsis thaliana|Rep: Putative uncharacterized protein F22I13.120 - Arabidopsis thaliana (Mouse-ear cress) Length = 1055 Score = 37.1 bits (82), Expect = 2.7 Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 4/121 (3%) Query: 915 IFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVKYXXX 974 I++ +T + I +LN + V + S G+AV+F +H + ++ +SG++ R + Sbjct: 914 IWTVALTNLAIAIVGIQLNAVSVVNLIMSIGIAVEFCVHISHAFLMSSGDREHRAREALE 973 Query: 975 XXXXXXXXXXXXXGFAGVFLL---RSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIV 1031 GV +L RS + +L L++ + + + FL +L + Sbjct: 974 TMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVI-IGFLHGLVFLPVILSLA 1032 Query: 1032 G 1032 G Sbjct: 1033 G 1033 Score = 36.3 bits (80), Expect = 4.7 Identities = 36/165 (21%), Positives = 79/165 (47%), Gaps = 6/165 (3%) Query: 418 LFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWK-MIGKQ 476 L +F I+ +LG A FY + + ++ +V+V++ +G+ F + + +I + Sbjct: 553 LVMFVYISVTLGDAPQFYTFYISSKVLLGLSGVVLVLLSVLGSVGVFSALGVKSTLIIME 612 Query: 477 LIKDNVVYQENGVLDINISSAGETILVQILEETMRHSIV----TIFITTLTTAVAFYASY 532 +I V+ + I + + LE+ + ++V +I + +L+ +AF Sbjct: 613 VIPFLVLAVGVDNMCILVHAVKRQPREVSLEQRISSALVEVGPSITLASLSEVLAFAVGA 672 Query: 533 VSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKK 577 +PA FS+FA A++++F L +T +++ + D K A + Sbjct: 673 FVPMPACRIFSMFAALAIMLDFFLQITAF-VALIVFDCKRSADNR 716 >UniRef50_Q9XWL9 Cluster: Putative uncharacterized protein ptr-18; n=2; Caenorhabditis|Rep: Putative uncharacterized protein ptr-18 - Caenorhabditis elegans Length = 858 Score = 37.1 bits (82), Expect = 2.7 Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 26/151 (17%) Query: 431 AYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIW-KMIGKQLIKDNVVYQENGV 489 A F +++ + P + + V ++L IG DD FI++ W + K ++D Sbjct: 271 ASFGHLFWMGFEYLPIVTV-VPFLILSIGVDDVFIFIHAWHRTPYKHSVRDR-------- 321 Query: 490 LDINISSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTA 549 + ET+ + +I IT+LT ++F + PAI F VF TA Sbjct: 322 ----------------MAETLADAGPSISITSLTNLLSFAIGIFTPTPAIYTFCVFISTA 365 Query: 550 VLVNFVLMMTWLPISVFIVDVKLYAKKKTFL 580 V+ +++ + + + + + +K +L Sbjct: 366 VIYDYIYQIFFFSAVLVLSGEREEQRKNAYL 396 >UniRef50_Q18129 Cluster: Patched related family protein 1; n=2; Caenorhabditis|Rep: Patched related family protein 1 - Caenorhabditis elegans Length = 956 Score = 37.1 bits (82), Expect = 2.7 Identities = 21/65 (32%), Positives = 39/65 (60%), Gaps = 5/65 (7%) Query: 908 VCALTAMIFSSTVTIAVL-VINNWKLNILESVAIST---SAGLAVDFSLHYALSYTNASG 963 +CA+ ++ +++ + VL ++ W +N L+SV+I T G +VD S H A +++ + G Sbjct: 798 ICAVAIVLSIASINVGVLGFMSFWGVN-LDSVSIITVIMCIGFSVDLSAHIAYAFSQSYG 856 Query: 964 NKSAR 968 N AR Sbjct: 857 NSHAR 861 >UniRef50_O29790 Cluster: Putative uncharacterized protein; n=1; Archaeoglobus fulgidus|Rep: Putative uncharacterized protein - Archaeoglobus fulgidus Length = 736 Score = 37.1 bits (82), Expect = 2.7 Identities = 17/59 (28%), Positives = 30/59 (50%) Query: 504 QILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLP 562 + LEE + H+ +F+ TT + F + IP++ FS ++ F+L T+LP Sbjct: 299 EALEEALNHTRFPLFMAMATTVIGFASMCAPGIPSLFWFSFLLSVGLITAFLLSNTFLP 357 >UniRef50_Q9Y6C5 Cluster: Protein patched homolog 2; n=14; Theria|Rep: Protein patched homolog 2 - Homo sapiens (Human) Length = 1203 Score = 37.1 bits (82), Expect = 2.7 Identities = 22/105 (20%), Positives = 47/105 (44%) Query: 867 SDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLV 926 S F F++ L ++A+ + F+V LN T+ + + + ++ Sbjct: 949 SPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMG 1008 Query: 927 INNWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVKY 971 KL+ + V + S G+ V+F++H AL + G+++ R + Sbjct: 1009 FLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAH 1053 >UniRef50_Q19127 Cluster: Niemann-Pick C1 protein homolog 1 precursor; n=2; Caenorhabditis|Rep: Niemann-Pick C1 protein homolog 1 precursor - Caenorhabditis elegans Length = 1383 Score = 37.1 bits (82), Expect = 2.7 Identities = 20/68 (29%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Query: 504 QILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPI 563 +I+ M ++ +F ++L A +F+ + +PAI F ++AG AVL++ VL T + + Sbjct: 737 EIVGMVMAGTMPAMFSSSLGCAFSFFIGGFTDLPAIRTFCLYAGLAVLIDVVLHCT-IFL 795 Query: 564 SVFIVDVK 571 ++F+ D + Sbjct: 796 ALFVWDTQ 803 >UniRef50_UPI00003650C0 Cluster: patched domain containing 3; n=1; Takifugu rubripes|Rep: patched domain containing 3 - Takifugu rubripes Length = 844 Score = 36.7 bits (81), Expect = 3.5 Identities = 17/47 (36%), Positives = 29/47 (61%) Query: 515 VTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWL 561 V+I ITTLT A+A + Y S ++ F ++AG +V ++ +T+L Sbjct: 381 VSISITTLTNALALFVGYSSPFGSVRSFCLYAGVSVCFCYLYSVTFL 427 >UniRef50_Q5QJP1 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Salmonella typhimurium Length = 1274 Score = 36.7 bits (81), Expect = 3.5 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 2/64 (3%) Query: 1017 WTYATFFLCSLLHIVGRSSIKESPSRERKPVSRVNSVSSGVPNLESHELEHLADSNRTNV 1076 WTY+T L ++ + S S + +KPV+ + S+ +PNLE + E+++ R Sbjct: 861 WTYSTLNLQNICFSLSHESENNSDTFRKKPVALIKSLR--IPNLEKYVYENISSFIRDVF 918 Query: 1077 THSQ 1080 HS+ Sbjct: 919 IHSE 922 >UniRef50_A5FXC8 Cluster: Exporter of the RND superfamily-like protein precursor; n=2; Proteobacteria|Rep: Exporter of the RND superfamily-like protein precursor - Acidiphilium cryptum (strain JF-5) Length = 858 Score = 36.7 bits (81), Expect = 3.5 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Query: 866 LSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVL 925 LSD QF +L G + LL+S AL + L+ A ++ V L ++ +TI+ Sbjct: 262 LSDEQF----ASLTQGMVAGLLISTALITLWLLLAVRSWRMIVPILATLLAGLALTISFA 317 Query: 926 VINNWKLNILESVAISTSAGLAVDFSLHYAL 956 + LN++ GLAVDF++ + + Sbjct: 318 ALAIGTLNLISVAFAILFVGLAVDFAIQFCV 348 >UniRef50_A4J5Y7 Cluster: Phosphatidate cytidylyltransferase; n=1; Desulfotomaculum reducens MI-1|Rep: Phosphatidate cytidylyltransferase - Desulfotomaculum reducens MI-1 Length = 261 Score = 36.7 bits (81), Expect = 3.5 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 4/80 (5%) Query: 378 FGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVY 437 F + + L + + W+I +GG+F+F ++Y + +++F I SL + F Y Sbjct: 40 FEISDILKGLKLNPSKWMIQIGGLFIFTSAYLYKDEYLGLMYVFLVIV-SLIMMAFLYPR 98 Query: 438 VFNLHFFPFMNLLVIVIVLG 457 V+ + F LV V+ LG Sbjct: 99 VYPVDVF---GNLVAVLYLG 115 >UniRef50_A3HZ07 Cluster: AmpG protein, beta-lactamase induction signal transducer; n=1; Algoriphagus sp. PR1|Rep: AmpG protein, beta-lactamase induction signal transducer - Algoriphagus sp. PR1 Length = 421 Score = 36.7 bits (81), Expect = 3.5 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 4/106 (3%) Query: 336 QKFVKNTMLFLPLPRSDTVLPYYKKLENSNMSYDNLVIPAIDFGLKNALFDI-WIIEDTW 394 QK K+ L++P +PY + S + Y L I D GL +L + W+++ W Sbjct: 3 QKTTKSPWLWVPSLYMTEGIPYIIIITVSVIMYKQLGIANSDIGLYTSLLYLPWVVKPIW 62 Query: 395 LIALGGIFVFACVWIYTRSLILTLFLFAAITFSL-GIAYFFYVYVF 439 + +F W + L+L + +F + FS G ++FF F Sbjct: 63 -SPIVDLFGTKRKWFLSMQLVLAI-VFICVGFSTSGNSFFFMTLAF 106 >UniRef50_A3HX91 Cluster: Putative ABC transport system, membrane protein; n=1; Algoriphagus sp. PR1|Rep: Putative ABC transport system, membrane protein - Algoriphagus sp. PR1 Length = 1016 Score = 36.7 bits (81), Expect = 3.5 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 7/137 (5%) Query: 374 PAIDFGL---KNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGI 430 P +DF L ++ L + I + GGIF FA ++++ + L L + ++ SL I Sbjct: 310 PQVDFDLTQDQSNLLNAAISNLETSLLFGGIFAFAVLFLFMKDYRLPLIIGVSLPSSLVI 369 Query: 431 AYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYV-KIWKMIGKQL-IKDNVVYQENG 488 ++ + Y FNL ++L + + +G+ D+A I + I + + L I + V N Sbjct: 370 SFLIF-YFFNLS-INIISLSGLALGIGMLIDNAIIVLDNITRKRDEGLPIFEACVEGVNE 427 Query: 489 VLDINISSAGETILVQI 505 V+ ISS T+ V I Sbjct: 428 VMGALISSVMTTLAVFI 444 >UniRef50_A0RMA9 Cluster: Hydrogenase 4 membrane subunit; n=1; Campylobacter fetus subsp. fetus 82-40|Rep: Hydrogenase 4 membrane subunit - Campylobacter fetus subsp. fetus (strain 82-40) Length = 650 Score = 36.7 bits (81), Expect = 3.5 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 9/138 (6%) Query: 368 YDNLVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFS 427 Y L IP I + + ++ I I T+ L G F+F+ +I T F+ I Sbjct: 28 YIGLAIPCI-ISIFSTIYFIKNINSTYGFKLAGNFLFSPHFIITPLSGFFSFIITFIAIG 86 Query: 428 LGIAYFFYVYVF----NLHFFPFM-NLLVIVIVLGIGADDAFIYVKIWK---MIGKQLIK 479 + I Y+ F NL F + N ++ ++L + + D F ++ +W+ +I L+K Sbjct: 87 ICIYTIGYIKEFKDRGNLAVFAALFNFFILSMLLVVSSSDVFSFIVLWEIMTLISALLLK 146 Query: 480 DNVVYQENGVLDINISSA 497 N N + I +S A Sbjct: 147 FNDEKHSNKTVMIYLSIA 164 >UniRef50_Q01KH5 Cluster: H0409D10.4 protein; n=5; Eukaryota|Rep: H0409D10.4 protein - Oryza sativa (Rice) Length = 1372 Score = 36.7 bits (81), Expect = 3.5 Identities = 21/70 (30%), Positives = 43/70 (61%), Gaps = 5/70 (7%) Query: 506 LEETMRHSIV----TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWL 561 LEE + ++V +I + +L +AF S ++ +PA FS+FA AVL++F+L ++ Sbjct: 705 LEERISTALVEVGPSITLASLAEVLAFAVSAINPMPATRVFSMFAALAVLLDFLLQVSAF 764 Query: 562 PISVFIVDVK 571 +++ ++D + Sbjct: 765 -VALIVLDFR 773 >UniRef50_UPI000038DBBD Cluster: COG0841: Cation/multidrug efflux pump; n=1; Nostoc punctiforme PCC 73102|Rep: COG0841: Cation/multidrug efflux pump - Nostoc punctiforme PCC 73102 Length = 1013 Score = 36.3 bits (80), Expect = 4.7 Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 3/132 (2%) Query: 396 IALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIV 455 IA+G + + ++++ R T+ AAIT L F V F M+L + + Sbjct: 338 IAIGIVLIIIVLYVFLREWRSTVI--AAITIPLSALAAFGVLSFVGQSLNLMSLGGLAVA 395 Query: 456 LGIGADDAFIYVK-IWKMIGKQLIKDNVVYQENGVLDINISSAGETILVQILEETMRHSI 514 +G+ DDA + ++ I + + K L V L + S+ T + L + + Sbjct: 396 IGLVIDDAIVVIENIDRQLQKDLDSTTAVAAAMAELTEPVISSTITTVAVFLPLGLLSGV 455 Query: 515 VTIFITTLTTAV 526 F T+LTT + Sbjct: 456 AGQFFTSLTTTL 467 >UniRef50_Q4FPX8 Cluster: RND superfamily multidrug efflux pump; n=8; Proteobacteria|Rep: RND superfamily multidrug efflux pump - Psychrobacter arcticum Length = 1036 Score = 36.3 bits (80), Expect = 4.7 Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 2/70 (2%) Query: 399 GGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGI 458 GGI V+++ R++ T+ A+ S+ I F +Y+F+ ++LL + +V+G+ Sbjct: 341 GGILAVVVVFLFLRNIRATIVAAVALPLSV-IPTFLGMYLFDFSL-NIISLLALSLVIGV 398 Query: 459 GADDAFIYVK 468 DDA + V+ Sbjct: 399 LVDDAIVEVE 408 >UniRef50_Q03SC1 Cluster: Predicted membrane protein; n=1; Lactobacillus brevis ATCC 367|Rep: Predicted membrane protein - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 1096 Score = 36.3 bits (80), Expect = 4.7 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 5/75 (6%) Query: 390 IEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMN- 448 ++ T +IA IF+F +W+ RS + LF + S+ + + + FPF N Sbjct: 178 VQKTEIIA--AIFIFLVLWLVFRSPVTPLFSLLTVDVSVITSISVVANLVDRFNFPFSNF 235 Query: 449 --LLVIVIVLGIGAD 461 + +++++ GIG D Sbjct: 236 TQVFIVIVLFGIGTD 250 >UniRef50_A6LJJ4 Cluster: Exporter of the RND superfamily-like protein precursor; n=1; Thermosipho melanesiensis BI429|Rep: Exporter of the RND superfamily-like protein precursor - Thermosipho melanesiensis BI429 Length = 771 Score = 36.3 bits (80), Expect = 4.7 Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 5/52 (9%) Query: 410 YTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLLVIVIVLGIGAD 461 + RSL ++ + +I ++GI YF V NL F+NLL++ I LGIG D Sbjct: 651 FKRSLQISFLVILSILSTIGIGYF--VLKINL---TFLNLLIVPIFLGIGVD 697 >UniRef50_Q9XXR9 Cluster: Putative uncharacterized protein ptr-19; n=2; Caenorhabditis|Rep: Putative uncharacterized protein ptr-19 - Caenorhabditis elegans Length = 1003 Score = 36.3 bits (80), Expect = 4.7 Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Query: 495 SSAGETILVQILEETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNF 554 +S+ ET L ++ET + V+I +T+LT ++F + P++ F +A AV+ + Sbjct: 379 TSSTET-LEHRMKETFADAAVSITVTSLTDLISFGVGCATPFPSVQMFCAYAVAAVIFTY 437 Query: 555 VLMMTW 560 + +T+ Sbjct: 438 IYQLTF 443 >UniRef50_Q4DFK7 Cluster: Putative uncharacterized protein; n=2; Trypanosoma cruzi|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 886 Score = 36.3 bits (80), Expect = 4.7 Identities = 23/87 (26%), Positives = 48/87 (55%), Gaps = 6/87 (6%) Query: 359 KKLENSNMSYDNLVIPA--IDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLIL 416 KK ++N+ +D ++ A + + N D + + ++ALGGIF+ + + RSL L Sbjct: 610 KKHASANVYFDYGILGASSASWAIMNESLDFFPFQI--VVALGGIFII--IMVIFRSLFL 665 Query: 417 TLFLFAAITFSLGIAYFFYVYVFNLHF 443 + L A + +++G+++ V VF ++ Sbjct: 666 PVRLIATVIYTIGVSFGVGVVVFQYNW 692 >UniRef50_A0A5F1 Cluster: Patched family protein,; n=1; Toxoplasma gondii RH|Rep: Patched family protein, - Toxoplasma gondii RH Length = 225 Score = 36.3 bits (80), Expect = 4.7 Identities = 35/181 (19%), Positives = 78/181 (43%), Gaps = 11/181 (6%) Query: 869 FQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVL-VI 927 F FY+ ++ S T+ + A GF V++ + L + A ++ + +A++ + Sbjct: 23 FVFYESDTSILSSTLTNM---AWAGFAVMLVSVLLLPSLWSATMVVLVLVLIDVAIIGFM 79 Query: 928 NNWKL--NILESVAISTSAGLAVDFSLHYALSYTNASGNKSARVKYXXXXXXXXXXXXXX 985 + W L N+L V + S G ++D++ H ++ + G + Sbjct: 80 HFWDLPLNMLTMVNLIISIGFSIDYATHICHTFCHCVGRTRDLRVFETLVLIGNPIFHGL 139 Query: 986 XXGFAGVFLL---RSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSSIKESPSR 1042 GV +L RS +L + L++++++ + L LL ++G + ++ P + Sbjct: 140 LSTLLGVSVLAFTRSYVL--RVFFKMMTLVLSLAFAHGVILLPVLLSLIGPMNSRKEPVK 197 Query: 1043 E 1043 E Sbjct: 198 E 198 >UniRef50_Q4J7L8 Cluster: Putative uncharacterized protein; n=1; Sulfolobus acidocaldarius|Rep: Putative uncharacterized protein - Sulfolobus acidocaldarius Length = 330 Score = 36.3 bits (80), Expect = 4.7 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 684 GVKAIDNGNHMDPAS--KGHLVFDENFSISDPKSQSWLLGFC--ARIKGQPFYQQTLGPL 739 GVK I NGN + +++F NFSIS+ S++ G C +RI G FY Q P Sbjct: 62 GVKLIKNGNLLTYQGFVANYILFPVNFSISNEMIVSFV-GICNLSRISGIVFYGQNFTPP 120 Query: 740 LPN 742 LP+ Sbjct: 121 LPD 123 >UniRef50_UPI00006CFF77 Cluster: Ferric reductase like transmembrane component family protein; n=1; Tetrahymena thermophila SB210|Rep: Ferric reductase like transmembrane component family protein - Tetrahymena thermophila SB210 Length = 488 Score = 35.9 bits (79), Expect = 6.2 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 5/93 (5%) Query: 394 WLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLG-IAYFFYVYVFNLHFFPFMNLLVI 452 WL LGG+ F + LF + SL I YF Y LH+ F ++VI Sbjct: 122 WLAVLGGVLHFLSTDYQWDGWFMLGSLFGMLGVSLWPIRYFLYEIFIRLHWIGF--IVVI 179 Query: 453 VIVLGIGADDAFIYVKIWKMIGKQLIKDNVVYQ 485 V ++ G D A + W + LIK V+Y+ Sbjct: 180 VGIILHGVDIAIYGLGYWGL--DFLIKQAVIYR 210 >UniRef50_UPI0000498B66 Cluster: hypothetical protein 145.t00006; n=2; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein 145.t00006 - Entamoeba histolytica HM-1:IMSS Length = 1124 Score = 35.9 bits (79), Expect = 6.2 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 371 LVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAIT 425 + +P DFGL N++ D+W L L I VF+ +W YT+ +IL F T Sbjct: 672 ITMPVSDFGLMNSVEDMWTAGVYPLAVL--IMVFSGIWPYTKLVILLFTWFMPST 724 >UniRef50_Q8EFP7 Cluster: AcrB/AcrD/AcrF family protein; n=21; Alteromonadales|Rep: AcrB/AcrD/AcrF family protein - Shewanella oneidensis Length = 1020 Score = 35.9 bits (79), Expect = 6.2 Identities = 17/63 (26%), Positives = 35/63 (55%) Query: 887 LLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGL 946 L+ A L FI+L NF ++ ++++ S +T+A + + + LNIL + + + G+ Sbjct: 334 LVGALLSFIILYLFLRNFKMTMIVVSSVPISIGMTLAAMYLLGYSLNILSMMGLLLAVGM 393 Query: 947 AVD 949 +D Sbjct: 394 LID 396 >UniRef50_Q73QH4 Cluster: Membrane protein, putative; n=1; Treponema denticola|Rep: Membrane protein, putative - Treponema denticola Length = 905 Score = 35.9 bits (79), Expect = 6.2 Identities = 33/171 (19%), Positives = 73/171 (42%), Gaps = 9/171 (5%) Query: 874 LQRTLASGTIVALLLSAALGFIVLIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLN 933 L + + ++++ +S + F++L + + + + S + ++ KLN Sbjct: 714 LNKLVVESQLISVGVSLLIVFLILSVYYKSAFAGLFGIIPLALSILINFGIMGRLGIKLN 773 Query: 934 ILESVAISTSAGLAVDFSLHYALSY------TNASGNKSARVKYXXXXXXXXXXXXXXXX 987 I ++ S + G+ VD+++H +Y T SG + + + Sbjct: 774 IGTAMVASFAIGIGVDYTIHLLAAYHKCFLKTKGSG-QFLYLTFLGSGKAILFNAVSVGA 832 Query: 988 GFAGVFLLRSNLLPYSQIGAFLVLIMTVSWTYATFFLCSLLHIVGRSSIKE 1038 GFA + + N+L S++G + LIM S + L LL+++ I++ Sbjct: 833 GFAVLMFSKFNML--SELGFLIALIMITSSLGSLTILPVLLNLMKPKFIRK 881 >UniRef50_O32182 Cluster: YusP protein; n=13; Bacillus|Rep: YusP protein - Bacillus subtilis Length = 541 Score = 35.9 bits (79), Expect = 6.2 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 6/110 (5%) Query: 375 AIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSL--GIAY 432 A+ FG K+ +D W I + +AL GI F V + IL ++LF TF+ I + Sbjct: 217 ALSFGGKDYAWDSWQILGLFALALIGIVSFIIVESKAKEPILPMYLFKNRTFTFLNLIGF 276 Query: 433 FFYVYVFN-LHFFP-FMNLLVIVIVLGIGA--DDAFIYVKIWKMIGKQLI 478 F + +F + F P FM +V V G I + I +IG QL+ Sbjct: 277 FMSIGMFGAITFVPFFMQGIVGVSASESGTIMTPMMISMIITSIIGGQLV 326 >UniRef50_Q3D1W5 Cluster: Regulatory protein, putative, truncation; n=8; Streptococcus agalactiae|Rep: Regulatory protein, putative, truncation - Streptococcus agalactiae H36B Length = 352 Score = 35.9 bits (79), Expect = 6.2 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 6/76 (7%) Query: 878 LASGTIVALLLSAALGFIV--LIPATLNFVTSVCALTAMIFSSTVTIAVLVINNWKLNIL 935 LA GT++ L+ A LG ++ L+P F T + A + I ++V N+K N + Sbjct: 21 LALGTVIVLIPGAILGELMKALLPMWSGFATLIAATAVATSMMGLVIGIMVGLNFKFNPI 80 Query: 936 ESVAISTSAGLAVDFS 951 + S S GLAV F+ Sbjct: 81 Q----SASLGLAVMFA 92 >UniRef50_Q0R4F8 Cluster: Transporter-like protein; n=3; Pseudomonas|Rep: Transporter-like protein - Pseudomonas fluorescens Length = 873 Score = 35.9 bits (79), Expect = 6.2 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 4/60 (6%) Query: 508 ETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAG----TAVLVNFVLMMTWLPI 563 ET R +V + +TT+TT F S + I +I F VF A++++ +L+ W+ I Sbjct: 382 ETQRLMVVPVVLTTVTTIATFMISTTNNIVSIRNFGVFMSIGLTAALIISLLLIPAWISI 441 >UniRef50_Q6AW16 Cluster: Patched family protein 3, isoform b; n=3; Caenorhabditis|Rep: Patched family protein 3, isoform b - Caenorhabditis elegans Length = 1361 Score = 35.9 bits (79), Expect = 6.2 Identities = 25/125 (20%), Positives = 56/125 (44%), Gaps = 7/125 (5%) Query: 846 EKWTQTELENAPAGMKCGWFLSDFQFYDLQRTLASGTIVALLLSAALGFIVLIPATLNFV 905 E++++ L N P+G+ F F++ TL A+ + A F V+ N Sbjct: 1109 EEYSERGLSNHPSGIA-------FTFWEQYLTLRWNLFQAICIIALAVFCVISILMFNPW 1161 Query: 906 TSVCALTAMIFSSTVTIAVLVINNWKLNILESVAISTSAGLAVDFSLHYALSYTNASGNK 965 + + ++ ++ + + K+N + +V + + G+ V+F+ H L++ A G Sbjct: 1162 AATLIMCIVVITTIELGGFMGLMGIKMNPISAVTLICAVGIGVEFTAHVELAFLTALGTI 1221 Query: 966 SARVK 970 R++ Sbjct: 1222 DQRLE 1226 >UniRef50_Q26592 Cluster: ORF 3 precursor; n=1; Schistosoma mansoni|Rep: ORF 3 precursor - Schistosoma mansoni (Blood fluke) Length = 393 Score = 35.9 bits (79), Expect = 6.2 Identities = 62/259 (23%), Positives = 108/259 (41%), Gaps = 25/259 (9%) Query: 371 LVIPAIDFGLKNALFDIWIIEDTWLIALGGIFVFACVWIYTRSLILTLFLFAAITFSLGI 430 L+I AI FG+ +F I I T L+ I V + I+ + L S+ + Sbjct: 57 LIILAIFFGV--TIFLI-IFSMTMLV----IPVLVVSVFFVTIFIIAILLVTIFVVSVFV 109 Query: 431 AYFFYVYVFNLHFFPFMNLLVIVIVLGIGADDAFIYVKIWKMIGKQLIKDN--VVYQENG 488 F + V + F LLV + V+ I FI + + ++ ++ N V Sbjct: 110 VTIFIIAVLLVTIFVISILLVTIFVVSILVVTLFITIFVRAILVVTILVINLFVTIFVRA 169 Query: 489 VLDINISSA-------GETILVQILEETMR--HSIVTIFITTLTTAVAFYASYVSYIPAI 539 +L I + A T+ V I T+ VTIF+ T+ F A +V I I Sbjct: 170 ILVITLFVAIFVRTILVITLFVAIFVRTILVITLFVTIFVRTILVITLFVAIFVRTILVI 229 Query: 540 NCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAKKKTFLDLVHKNVNEMWENIRIVLN 599 F + + +L++T L ISVFI+ + + + ++ V ++ V+ Sbjct: 230 TLF-----VTIFIISILLVTILVISVFIIAILTISIFVISILIITIFVISVFVITIFVVT 284 Query: 600 RF--TIICVTKFHIAFVVV 616 F T++ ++ F +AF +V Sbjct: 285 IFAITVLVISIFIVAFFIV 303 >UniRef50_A7RFX5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 704 Score = 35.9 bits (79), Expect = 6.2 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 8/73 (10%) Query: 154 DEHAVLLKDHSRKQWLSLKNMQRI--ADKPINLNYASGTCGPP--ISDYAHLVITNTDN- 208 DE + +H R+Q ++NMQ +D PIN+ + SGT G P ++ H ++ N + Sbjct: 232 DEFMKIGGEHERQQ---IRNMQMALQSDDPINIQFTSGTTGNPKGVTLTHHGILNNAASV 288 Query: 209 SSLLSYKNVERLC 221 +L+Y R+C Sbjct: 289 GDILNYAEYTRVC 301 >UniRef50_A5K0C5 Cluster: Dynein heavy chain, putative; n=2; Plasmodium|Rep: Dynein heavy chain, putative - Plasmodium vivax Length = 3116 Score = 35.9 bits (79), Expect = 6.2 Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 5/72 (6%) Query: 572 LYAKKKTFLDLVHKNVNEMWENIRIVLNRFTIICVTKFHIAFVVVMGALGF---ISLVVV 628 LY K F++ KN+ ++++NI +N IIC+ K ++++ A+ F I+ V++ Sbjct: 634 LYINTKMFVEFYFKNILQVYKNISKNINSSMIICMNKKRA--IILLNAIAFILNINTVLI 691 Query: 629 FYSPGLHLPDSK 640 S L P K Sbjct: 692 NKSSNLENPQDK 703 >UniRef50_UPI0000586B35 Cluster: PREDICTED: similar to Niemann-Pick C disease protein isoform 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Niemann-Pick C disease protein isoform 1 - Strongylocentrotus purpuratus Length = 1332 Score = 35.5 bits (78), Expect = 8.2 Identities = 14/44 (31%), Positives = 30/44 (68%) Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMT 559 ++ +T+ + ++AF +S +PA+ FS++A AV ++F+L +T Sbjct: 774 SMLLTSSSESIAFGIGAMSSMPAVRAFSMYAAVAVAMDFLLQIT 817 >UniRef50_Q0ARW7 Cluster: Exporter of the RND superfamily; n=2; Proteobacteria|Rep: Exporter of the RND superfamily - Maricaulis maris (strain MCS10) Length = 811 Score = 35.5 bits (78), Expect = 8.2 Identities = 17/69 (24%), Positives = 35/69 (50%) Query: 508 ETMRHSIVTIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFI 567 + +R + + + IT+LTT + F A +S P ++ ++L +T+LP V + Sbjct: 341 DAVRINFLAVSITSLTTVIGFMALNLSDSPPFGHLGTMTAIGIIAAWLLSITFLPAIVSL 400 Query: 568 VDVKLYAKK 576 + +K +K Sbjct: 401 LPMKASPRK 409 >UniRef50_A6LJ70 Cluster: Major facilitator superfamily MFS_1; n=1; Thermosipho melanesiensis BI429|Rep: Major facilitator superfamily MFS_1 - Thermosipho melanesiensis BI429 Length = 406 Score = 35.5 bits (78), Expect = 8.2 Identities = 15/43 (34%), Positives = 24/43 (55%) Query: 408 WIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHFFPFMNLL 450 W + + L LTLF A + +GI Y+F Y ++ F F+ L+ Sbjct: 278 WKFKKKLNLTLFFGAIVIMLIGITYYFNFYYISIILFVFVYLI 320 >UniRef50_A3D7T1 Cluster: Putative uncharacterized protein; n=1; Shewanella baltica OS155|Rep: Putative uncharacterized protein - Shewanella baltica OS155 Length = 119 Score = 35.5 bits (78), Expect = 8.2 Identities = 21/77 (27%), Positives = 43/77 (55%), Gaps = 3/77 (3%) Query: 402 FVFACVWIYTRSLILTLFLFAAITFSLGIAYFFYVYVFNLHF-FPFMNLLVIVIVLGIGA 460 F F+ + I+ + L+ +++FA I GI + F+ ++ +P +NL+VI++ L + + Sbjct: 12 FTFSSLGIFRKILLGIVWIFAVIFILGGIIWTFFPHIMQDELNYPLVNLIVIIVFLNLFS 71 Query: 461 DDAFIYVKIWKMIGKQL 477 +I+ + K KQL Sbjct: 72 --FWIHFAVCKRKTKQL 86 >UniRef50_Q6CBA1 Cluster: Similar to tr|Q12200 Saccharomyces cerevisiae YPL006W NCR1; n=1; Yarrowia lipolytica|Rep: Similar to tr|Q12200 Saccharomyces cerevisiae YPL006W NCR1 - Yarrowia lipolytica (Candida lipolytica) Length = 1239 Score = 35.5 bits (78), Expect = 8.2 Identities = 29/117 (24%), Positives = 58/117 (49%), Gaps = 6/117 (5%) Query: 516 TIFITTLTTAVAFYASYVSYIPAINCFSVFAGTAVLVNFVLMMTWLPISVFIVDVKLYAK 575 +I I+ +T +AF + +PA+ F+++A AV +N +L +T + +SV +D + + Sbjct: 683 SIVISAITETLAFGLAATVKMPAVRNFAIYAAGAVFINAILQLT-IFVSVMALDQRRQSA 741 Query: 576 KKTFLDL--VHKNVNEMWENI--RIVLNRFTIICVTKFHIAFVV-VMGALGFISLVV 627 D + N+ E EN+ R++ + + K V+ V G +SL++ Sbjct: 742 PIQLADSYDLDFNILEHRENLFSRLIRRYYAPFLLKKKTKKIVLAVFGTWAAVSLIL 798 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.324 0.138 0.422 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,166,495,807 Number of Sequences: 1657284 Number of extensions: 47215250 Number of successful extensions: 156232 Number of sequences better than 10.0: 145 Number of HSP's better than 10.0 without gapping: 89 Number of HSP's successfully gapped in prelim test: 56 Number of HSP's that attempted gapping in prelim test: 155728 Number of HSP's gapped (non-prelim): 415 length of query: 1118 length of database: 575,637,011 effective HSP length: 109 effective length of query: 1009 effective length of database: 394,993,055 effective search space: 398547992495 effective search space used: 398547992495 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 40 (21.6 bits) S2: 78 (35.5 bits)
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