BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000467-TA|BGIBMGA000467-PA|IPR002126|Cadherin, IPR006209|EGF-like, IPR012680|Laminin G, subdomain 2, IPR002049|EGF-like, laminin, IPR001879|Hormone receptor, extracellular, IPR000203|GPS, IPR000152|Aspartic acid and asparagine hydroxylation site, IPR013032|EGF-like region, IPR000005|Helix-turn-helix, AraC type, IPR000083|Fibronectin, type I, IPR006210|EGF, IPR001791|Laminin G, IPR001881|EGF-like calcium-binding, IPR000742|EGF-like, type 3 (2796 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_18656| Best HMM Match : No HMM Matches (HMM E-Value=.) 614 e-175 SB_22798| Best HMM Match : Cadherin (HMM E-Value=0) 434 e-121 SB_58036| Best HMM Match : Cadherin (HMM E-Value=0) 386 e-106 SB_38622| Best HMM Match : No HMM Matches (HMM E-Value=.) 385 e-106 SB_25361| Best HMM Match : Cadherin (HMM E-Value=0) 384 e-106 SB_34906| Best HMM Match : Cadherin (HMM E-Value=0) 368 e-101 SB_46477| Best HMM Match : No HMM Matches (HMM E-Value=.) 351 4e-96 SB_48962| Best HMM Match : Cadherin (HMM E-Value=0) 345 3e-94 SB_45916| Best HMM Match : Cadherin (HMM E-Value=0) 341 5e-93 SB_5763| Best HMM Match : Cadherin (HMM E-Value=0) 332 2e-90 SB_47886| Best HMM Match : Cadherin (HMM E-Value=0) 329 2e-89 SB_51779| Best HMM Match : No HMM Matches (HMM E-Value=.) 304 7e-82 SB_1988| Best HMM Match : No HMM Matches (HMM E-Value=.) 288 5e-77 SB_15712| Best HMM Match : Cadherin (HMM E-Value=0) 277 7e-74 SB_36047| Best HMM Match : No HMM Matches (HMM E-Value=.) 274 5e-73 SB_9756| Best HMM Match : Cadherin (HMM E-Value=0) 268 4e-71 SB_41246| Best HMM Match : Cadherin (HMM E-Value=0) 266 2e-70 SB_55456| Best HMM Match : Cadherin (HMM E-Value=0) 242 3e-63 SB_18678| Best HMM Match : No HMM Matches (HMM E-Value=.) 240 1e-62 SB_22450| Best HMM Match : No HMM Matches (HMM E-Value=.) 238 4e-62 SB_9507| Best HMM Match : Cadherin (HMM E-Value=0) 238 4e-62 SB_28228| Best HMM Match : Cadherin (HMM E-Value=0) 227 1e-58 SB_27857| Best HMM Match : Cadherin (HMM E-Value=0) 221 9e-57 SB_56770| Best HMM Match : Cadherin (HMM E-Value=0) 216 2e-55 SB_35949| Best HMM Match : Cadherin (HMM E-Value=0) 214 1e-54 SB_50345| Best HMM Match : Cadherin (HMM E-Value=0) 202 4e-51 SB_56686| Best HMM Match : Cadherin (HMM E-Value=0) 199 2e-50 SB_40275| Best HMM Match : Cadherin (HMM E-Value=0) 196 2e-49 SB_35963| Best HMM Match : Cadherin (HMM E-Value=0) 191 6e-48 SB_7364| Best HMM Match : Cadherin (HMM E-Value=0) 182 4e-45 SB_18765| Best HMM Match : Cadherin (HMM E-Value=0) 175 6e-43 SB_44524| Best HMM Match : Cadherin (HMM E-Value=0) 173 1e-42 SB_33995| Best HMM Match : Cadherin (HMM E-Value=3e-39) 165 5e-40 SB_39408| Best HMM Match : Cadherin (HMM E-Value=0) 165 6e-40 SB_34907| Best HMM Match : Cadherin (HMM E-Value=0) 162 4e-39 SB_51258| Best HMM Match : Cadherin (HMM E-Value=0) 153 2e-36 SB_24627| Best HMM Match : Cadherin (HMM E-Value=0) 145 4e-34 SB_14427| Best HMM Match : Cadherin (HMM E-Value=0) 144 7e-34 SB_56813| Best HMM Match : Cadherin (HMM E-Value=5.8e-40) 137 1e-31 SB_30491| Best HMM Match : No HMM Matches (HMM E-Value=.) 136 2e-31 SB_28202| Best HMM Match : Cadherin (HMM E-Value=1.8e-29) 133 2e-30 SB_4130| Best HMM Match : Cadherin (HMM E-Value=9.3e-29) 124 1e-27 SB_10746| Best HMM Match : Cadherin (HMM E-Value=0) 119 4e-26 SB_4448| Best HMM Match : No HMM Matches (HMM E-Value=.) 117 2e-25 SB_34938| Best HMM Match : Cadherin (HMM E-Value=1e-25) 109 2e-23 SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0) 106 2e-22 SB_40244| Best HMM Match : Cadherin (HMM E-Value=0) 105 4e-22 SB_16935| Best HMM Match : Cadherin (HMM E-Value=0) 102 5e-21 SB_21336| Best HMM Match : No HMM Matches (HMM E-Value=.) 101 6e-21 SB_36411| Best HMM Match : No HMM Matches (HMM E-Value=.) 97 2e-19 SB_15158| Best HMM Match : Cadherin (HMM E-Value=7.5e-23) 96 3e-19 SB_57964| Best HMM Match : No HMM Matches (HMM E-Value=.) 96 4e-19 SB_32317| Best HMM Match : Cadherin (HMM E-Value=1.5e-28) 86 3e-16 SB_56860| Best HMM Match : Cadherin (HMM E-Value=4.4e-16) 82 7e-15 SB_10800| Best HMM Match : No HMM Matches (HMM E-Value=.) 76 4e-13 SB_45116| Best HMM Match : EGF (HMM E-Value=0) 75 1e-12 SB_54100| Best HMM Match : No HMM Matches (HMM E-Value=.) 74 1e-12 SB_4874| Best HMM Match : No HMM Matches (HMM E-Value=.) 73 3e-12 SB_23044| Best HMM Match : No HMM Matches (HMM E-Value=.) 71 1e-11 SB_16968| Best HMM Match : Laminin_EGF (HMM E-Value=0) 71 1e-11 SB_35857| Best HMM Match : No HMM Matches (HMM E-Value=.) 71 2e-11 SB_35310| Best HMM Match : Cadherin (HMM E-Value=5.9e-23) 71 2e-11 SB_35194| Best HMM Match : EGF_2 (HMM E-Value=0) 70 2e-11 SB_6200| Best HMM Match : Laminin_EGF (HMM E-Value=0) 70 2e-11 SB_10656| Best HMM Match : No HMM Matches (HMM E-Value=.) 68 9e-11 SB_30436| Best HMM Match : No HMM Matches (HMM E-Value=.) 68 9e-11 SB_7853| Best HMM Match : Cadherin (HMM E-Value=9.9) 68 1e-10 SB_32515| Best HMM Match : FAINT (HMM E-Value=4.5) 67 2e-10 SB_29802| Best HMM Match : Laminin_EGF (HMM E-Value=0) 66 5e-10 SB_8046| Best HMM Match : No HMM Matches (HMM E-Value=.) 65 9e-10 SB_25851| Best HMM Match : Laminin_G_2 (HMM E-Value=0) 64 2e-09 SB_552| Best HMM Match : Laminin_EGF (HMM E-Value=1.3e-23) 64 2e-09 SB_49286| Best HMM Match : Laminin_N (HMM E-Value=0) 63 3e-09 SB_22952| Best HMM Match : EGF_2 (HMM E-Value=2e-23) 63 3e-09 SB_42841| Best HMM Match : No HMM Matches (HMM E-Value=.) 63 3e-09 SB_52794| Best HMM Match : No HMM Matches (HMM E-Value=.) 62 6e-09 SB_56285| Best HMM Match : No HMM Matches (HMM E-Value=.) 62 8e-09 SB_50568| Best HMM Match : EGF (HMM E-Value=0) 62 8e-09 SB_9550| Best HMM Match : GPS (HMM E-Value=1.6e-11) 61 1e-08 SB_52147| Best HMM Match : EGF (HMM E-Value=0) 61 1e-08 SB_32355| Best HMM Match : Laminin_EGF (HMM E-Value=0) 61 1e-08 SB_10244| Best HMM Match : Laminin_EGF (HMM E-Value=0) 61 1e-08 SB_33333| Best HMM Match : No HMM Matches (HMM E-Value=.) 60 2e-08 SB_31541| Best HMM Match : EGF (HMM E-Value=0) 60 2e-08 SB_25612| Best HMM Match : Cadherin (HMM E-Value=0.034) 60 3e-08 SB_31961| Best HMM Match : EGF (HMM E-Value=0) 59 6e-08 SB_32940| Best HMM Match : EGF (HMM E-Value=0) 59 6e-08 SB_58558| Best HMM Match : EGF (HMM E-Value=0) 58 1e-07 SB_20112| Best HMM Match : EGF (HMM E-Value=0) 58 1e-07 SB_18364| Best HMM Match : Cadherin (HMM E-Value=3e-12) 57 2e-07 SB_12265| Best HMM Match : Cadherin (HMM E-Value=1.3e-10) 57 2e-07 SB_49765| Best HMM Match : EGF (HMM E-Value=0) 56 3e-07 SB_40116| Best HMM Match : EGF (HMM E-Value=0) 56 3e-07 SB_471| Best HMM Match : Laminin_EGF (HMM E-Value=0) 56 3e-07 SB_43550| Best HMM Match : Laminin_EGF (HMM E-Value=0) 56 4e-07 SB_9705| Best HMM Match : Cadherin (HMM E-Value=0.013) 55 7e-07 SB_32282| Best HMM Match : Laminin_G_2 (HMM E-Value=0) 55 9e-07 SB_22642| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 1e-06 SB_2045| Best HMM Match : EGF (HMM E-Value=0) 54 2e-06 SB_8580| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 2e-06 SB_54839| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 2e-06 SB_16910| Best HMM Match : EGF (HMM E-Value=0) 53 3e-06 SB_3456| Best HMM Match : No HMM Matches (HMM E-Value=.) 53 3e-06 SB_20264| Best HMM Match : No HMM Matches (HMM E-Value=.) 53 4e-06 SB_2152| Best HMM Match : EGF (HMM E-Value=0) 53 4e-06 SB_13309| Best HMM Match : EGF (HMM E-Value=0) 52 7e-06 SB_16967| Best HMM Match : Laminin_EGF (HMM E-Value=0) 52 7e-06 SB_8425| Best HMM Match : EGF (HMM E-Value=0) 52 7e-06 SB_59261| Best HMM Match : No HMM Matches (HMM E-Value=.) 52 9e-06 SB_28495| Best HMM Match : No HMM Matches (HMM E-Value=.) 51 1e-05 SB_786| Best HMM Match : EGF (HMM E-Value=0) 51 1e-05 SB_57511| Best HMM Match : EGF_CA (HMM E-Value=0) 51 1e-05 SB_45521| Best HMM Match : F5_F8_type_C (HMM E-Value=8.6e-23) 50 2e-05 SB_18560| Best HMM Match : No HMM Matches (HMM E-Value=.) 50 2e-05 SB_34444| Best HMM Match : Cadherin (HMM E-Value=0.0043) 50 2e-05 SB_26697| Best HMM Match : EGF (HMM E-Value=7.5e-34) 50 2e-05 SB_4999| Best HMM Match : EGF_CA (HMM E-Value=0) 50 2e-05 SB_46333| Best HMM Match : EGF (HMM E-Value=1.10001e-40) 50 3e-05 SB_49700| Best HMM Match : No HMM Matches (HMM E-Value=.) 50 3e-05 SB_37565| Best HMM Match : No HMM Matches (HMM E-Value=.) 50 3e-05 SB_34555| Best HMM Match : EGF (HMM E-Value=7.00649e-45) 50 3e-05 SB_6077| Best HMM Match : EGF (HMM E-Value=0) 50 3e-05 SB_40912| Best HMM Match : No HMM Matches (HMM E-Value=.) 50 4e-05 SB_50709| Best HMM Match : No HMM Matches (HMM E-Value=.) 49 5e-05 SB_22953| Best HMM Match : EGF_2 (HMM E-Value=1.3e-14) 49 5e-05 SB_3431| Best HMM Match : EGF (HMM E-Value=1.8e-08) 49 5e-05 SB_12832| Best HMM Match : No HMM Matches (HMM E-Value=.) 49 6e-05 SB_40516| Best HMM Match : Cadherin (HMM E-Value=0.042) 48 8e-05 SB_23966| Best HMM Match : EGF (HMM E-Value=2.4e-40) 48 8e-05 SB_16748| Best HMM Match : No HMM Matches (HMM E-Value=.) 48 8e-05 SB_3457| Best HMM Match : No HMM Matches (HMM E-Value=.) 48 8e-05 SB_52148| Best HMM Match : EGF (HMM E-Value=0) 48 1e-04 SB_48268| Best HMM Match : No HMM Matches (HMM E-Value=.) 48 1e-04 SB_42006| Best HMM Match : EGF_2 (HMM E-Value=8.7e-05) 48 1e-04 SB_21404| Best HMM Match : VWA (HMM E-Value=8.1e-27) 48 1e-04 SB_41690| Best HMM Match : DSL (HMM E-Value=0) 48 1e-04 SB_35429| Best HMM Match : Laminin_EGF (HMM E-Value=5.3e-17) 48 1e-04 SB_1249| Best HMM Match : Cadherin (HMM E-Value=0.0083) 48 1e-04 SB_9975| Best HMM Match : 7tm_2 (HMM E-Value=1.9e-38) 48 1e-04 SB_46889| Best HMM Match : No HMM Matches (HMM E-Value=.) 47 2e-04 SB_11569| Best HMM Match : No HMM Matches (HMM E-Value=.) 47 2e-04 SB_26778| Best HMM Match : No HMM Matches (HMM E-Value=.) 47 2e-04 SB_47530| Best HMM Match : No HMM Matches (HMM E-Value=.) 47 3e-04 SB_44915| Best HMM Match : VWA (HMM E-Value=0) 47 3e-04 SB_32721| Best HMM Match : No HMM Matches (HMM E-Value=.) 47 3e-04 SB_29838| Best HMM Match : EGF (HMM E-Value=1.2e-15) 47 3e-04 SB_13163| Best HMM Match : VWA (HMM E-Value=2.3e-32) 47 3e-04 SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0) 47 3e-04 SB_5993| Best HMM Match : EGF_2 (HMM E-Value=9e-14) 47 3e-04 SB_4760| Best HMM Match : EGF (HMM E-Value=8.29989e-42) 47 3e-04 SB_46360| Best HMM Match : EGF (HMM E-Value=0) 47 3e-04 SB_44887| Best HMM Match : EGF (HMM E-Value=4.1e-09) 47 3e-04 SB_26480| Best HMM Match : EGF (HMM E-Value=0) 47 3e-04 SB_33722| Best HMM Match : EGF_CA (HMM E-Value=0) 46 3e-04 SB_22957| Best HMM Match : EGF (HMM E-Value=7e-39) 46 3e-04 SB_40913| Best HMM Match : No HMM Matches (HMM E-Value=.) 46 3e-04 SB_48384| Best HMM Match : No HMM Matches (HMM E-Value=.) 46 4e-04 SB_36058| Best HMM Match : VWA (HMM E-Value=7.4e-23) 46 6e-04 SB_28093| Best HMM Match : VWA (HMM E-Value=4.4e-33) 46 6e-04 SB_54456| Best HMM Match : EGF (HMM E-Value=2.3e-31) 46 6e-04 SB_39378| Best HMM Match : VWA (HMM E-Value=0) 46 6e-04 SB_5376| Best HMM Match : EGF_CA (HMM E-Value=0) 46 6e-04 SB_30234| Best HMM Match : No HMM Matches (HMM E-Value=.) 45 8e-04 SB_15312| Best HMM Match : EGF (HMM E-Value=7.1e-21) 45 8e-04 SB_53619| Best HMM Match : GPS (HMM E-Value=2.4e-15) 45 8e-04 SB_40564| Best HMM Match : Laminin_EGF (HMM E-Value=3.5e-12) 45 8e-04 SB_52271| Best HMM Match : No HMM Matches (HMM E-Value=.) 45 0.001 SB_16119| Best HMM Match : EGF (HMM E-Value=2e-20) 45 0.001 SB_52861| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.001 SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.001 SB_26578| Best HMM Match : EGF (HMM E-Value=2.2e-35) 44 0.001 SB_26267| Best HMM Match : TSP_C (HMM E-Value=0) 44 0.001 SB_26085| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.001 SB_54230| Best HMM Match : EGF (HMM E-Value=0) 44 0.001 SB_33876| Best HMM Match : EGF (HMM E-Value=2.4e-08) 44 0.001 SB_3578| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.001 SB_58129| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.002 SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.002 SB_48589| Best HMM Match : EGF (HMM E-Value=2e-19) 44 0.002 SB_32722| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.002 SB_12742| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.002 SB_11540| Best HMM Match : EGF (HMM E-Value=1.5e-25) 44 0.002 SB_45954| Best HMM Match : VWA (HMM E-Value=4e-26) 44 0.002 SB_5527| Best HMM Match : EGF_CA (HMM E-Value=1e-26) 44 0.002 SB_33579| Best HMM Match : Laminin_G_2 (HMM E-Value=3.2e-34) 44 0.002 SB_30923| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.002 SB_27599| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.002 SB_42661| Best HMM Match : No HMM Matches (HMM E-Value=.) 43 0.003 SB_14079| Best HMM Match : No HMM Matches (HMM E-Value=.) 43 0.003 SB_7343| Best HMM Match : EGF (HMM E-Value=0) 43 0.003 SB_5020| Best HMM Match : No HMM Matches (HMM E-Value=.) 43 0.003 SB_37317| Best HMM Match : EGF_CA (HMM E-Value=6.6e-25) 43 0.004 SB_28272| Best HMM Match : EGF (HMM E-Value=2.6e-15) 43 0.004 SB_20457| Best HMM Match : fn3 (HMM E-Value=5.1e-12) 43 0.004 SB_37171| Best HMM Match : EGF (HMM E-Value=2.6e-15) 43 0.004 SB_31622| Best HMM Match : EGF (HMM E-Value=4.2e-09) 43 0.004 SB_19665| Best HMM Match : No HMM Matches (HMM E-Value=.) 43 0.004 SB_32719| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.005 SB_26949| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.005 SB_23501| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.005 SB_21594| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.005 SB_33543| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.005 SB_32196| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.005 SB_44376| Best HMM Match : EGF_CA (HMM E-Value=7.8e-22) 42 0.007 SB_34553| Best HMM Match : F5_F8_type_C (HMM E-Value=8.3e-22) 42 0.007 SB_33149| Best HMM Match : DSL (HMM E-Value=5.60519e-45) 42 0.007 SB_50993| Best HMM Match : EGF (HMM E-Value=3.4e-19) 42 0.009 SB_47717| Best HMM Match : EGF (HMM E-Value=1.9e-29) 42 0.009 SB_52863| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.012 SB_47423| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.012 SB_47176| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.012 SB_41795| Best HMM Match : EGF (HMM E-Value=8.7e-11) 41 0.012 SB_32588| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.012 SB_14770| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.012 SB_7289| Best HMM Match : EGF_CA (HMM E-Value=0) 41 0.012 SB_4732| Best HMM Match : EGF (HMM E-Value=2.4e-10) 41 0.012 SB_57080| Best HMM Match : EGF_CA (HMM E-Value=1.4013e-43) 41 0.012 SB_41915| Best HMM Match : F5_F8_type_C (HMM E-Value=9.1e-13) 41 0.012 SB_15410| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.012 SB_48923| Best HMM Match : EGF_CA (HMM E-Value=3.2e-27) 41 0.016 SB_41903| Best HMM Match : HRM (HMM E-Value=0.00061) 41 0.016 SB_39963| Best HMM Match : EGF (HMM E-Value=1.4e-13) 41 0.016 SB_39510| Best HMM Match : VWA (HMM E-Value=0) 41 0.016 SB_33920| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.016 SB_12645| Best HMM Match : Laminin_EGF (HMM E-Value=3e-31) 41 0.016 SB_6849| Best HMM Match : EGF_2 (HMM E-Value=9.3e-11) 41 0.016 SB_58051| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.016 SB_26475| Best HMM Match : Cadherin (HMM E-Value=0.009) 41 0.016 SB_5780| Best HMM Match : EGF_CA (HMM E-Value=0) 41 0.016 SB_7527| Best HMM Match : DSL (HMM E-Value=2.5e-34) 40 0.022 SB_34550| Best HMM Match : VWA (HMM E-Value=0) 40 0.022 SB_1891| Best HMM Match : EGF (HMM E-Value=6.5e-15) 40 0.022 SB_53569| Best HMM Match : EGF_CA (HMM E-Value=0) 40 0.029 SB_14925| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.029 SB_3454| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.029 SB_48850| Best HMM Match : EGF_CA (HMM E-Value=2.1e-27) 40 0.029 SB_40335| Best HMM Match : EGF (HMM E-Value=2.5e-09) 40 0.029 SB_20425| Best HMM Match : EGF_CA (HMM E-Value=1.2e-20) 40 0.029 SB_15408| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.029 SB_7767| Best HMM Match : Laminin_EGF (HMM E-Value=3.4e-05) 40 0.029 SB_3977| Best HMM Match : EGF (HMM E-Value=1.8e-09) 40 0.029 SB_3108| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.029 SB_7933| Best HMM Match : GCC2_GCC3 (HMM E-Value=1.4e-18) 40 0.038 SB_58992| Best HMM Match : VWA (HMM E-Value=2.4e-15) 40 0.038 SB_43977| Best HMM Match : VWA (HMM E-Value=4.9e-13) 40 0.038 SB_32754| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.038 SB_27540| Best HMM Match : Laminin_EGF (HMM E-Value=5.4e-12) 40 0.038 SB_7814| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.038 SB_34004| Best HMM Match : No HMM Matches (HMM E-Value=.) 39 0.050 SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40) 39 0.050 SB_18916| Best HMM Match : GPS (HMM E-Value=1e-17) 39 0.050 SB_51485| Best HMM Match : Laminin_EGF (HMM E-Value=0.0035) 39 0.050 SB_32431| Best HMM Match : No HMM Matches (HMM E-Value=.) 39 0.050 SB_32430| Best HMM Match : No HMM Matches (HMM E-Value=.) 39 0.050 SB_26028| Best HMM Match : EGF (HMM E-Value=0.00014) 39 0.050 SB_15843| Best HMM Match : VWA (HMM E-Value=4.1e-35) 39 0.050 SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0) 39 0.066 SB_27751| Best HMM Match : Laminin_G_2 (HMM E-Value=1e-06) 39 0.066 SB_59742| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.088 SB_52403| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.088 SB_42659| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.088 SB_41113| Best HMM Match : VWA (HMM E-Value=1.8e-21) 38 0.088 SB_35900| Best HMM Match : EGF_CA (HMM E-Value=2.5e-38) 38 0.088 SB_20528| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.088 SB_54457| Best HMM Match : EGF (HMM E-Value=4.6e-31) 38 0.088 SB_39083| Best HMM Match : PhaC_N (HMM E-Value=0.7) 38 0.088 SB_15637| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.088 SB_8084| Best HMM Match : EGF_CA (HMM E-Value=2.8026e-45) 38 0.088 SB_56752| Best HMM Match : EGF (HMM E-Value=8.3e-10) 38 0.12 SB_47667| Best HMM Match : Ldl_recept_a (HMM E-Value=0) 38 0.12 SB_36893| Best HMM Match : Fibrinogen_C (HMM E-Value=2.4e-24) 38 0.12 SB_32444| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.12 SB_11375| Best HMM Match : EGF_CA (HMM E-Value=0) 38 0.12 SB_45136| Best HMM Match : EGF_CA (HMM E-Value=8.7e-36) 38 0.12 SB_9474| Best HMM Match : EGF (HMM E-Value=2e-08) 38 0.12 SB_5962| Best HMM Match : EGF (HMM E-Value=8.5e-09) 38 0.12 SB_51974| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.15 SB_50111| Best HMM Match : GCC2_GCC3 (HMM E-Value=0) 38 0.15 SB_18624| Best HMM Match : EGF (HMM E-Value=7.8e-06) 38 0.15 SB_42888| Best HMM Match : EGF (HMM E-Value=8.4e-20) 38 0.15 SB_22619| Best HMM Match : TSP_1 (HMM E-Value=8.5e-14) 37 0.20 SB_45836| Best HMM Match : EGF (HMM E-Value=6.7e-21) 37 0.20 SB_38753| Best HMM Match : No HMM Matches (HMM E-Value=.) 37 0.20 SB_12543| Best HMM Match : TSP_1 (HMM E-Value=1.4e-07) 37 0.20 SB_56964| Best HMM Match : Zona_pellucida (HMM E-Value=0) 37 0.27 SB_49295| Best HMM Match : No HMM Matches (HMM E-Value=.) 37 0.27 SB_43576| Best HMM Match : EGF_CA (HMM E-Value=2.7e-38) 37 0.27 SB_30653| Best HMM Match : Cadherin (HMM E-Value=0.0018) 37 0.27 SB_51462| Best HMM Match : Ion_trans_2 (HMM E-Value=2.3e-15) 37 0.27 SB_41271| Best HMM Match : EGF (HMM E-Value=1.2e-20) 37 0.27 SB_28917| Best HMM Match : No HMM Matches (HMM E-Value=.) 37 0.27 SB_24004| Best HMM Match : EGF (HMM E-Value=5.7e-14) 37 0.27 SB_14763| Best HMM Match : Zona_pellucida (HMM E-Value=0) 37 0.27 SB_42084| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.35 SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.35 SB_12997| Best HMM Match : DSL (HMM E-Value=1.4013e-45) 36 0.35 SB_11257| Best HMM Match : GCC2_GCC3 (HMM E-Value=2.7e-11) 36 0.35 SB_50906| Best HMM Match : EGF (HMM E-Value=3.5e-08) 36 0.35 SB_10156| Best HMM Match : DSL (HMM E-Value=3.3e-35) 36 0.35 SB_825| Best HMM Match : EGF (HMM E-Value=5.6e-08) 36 0.35 SB_37500| Best HMM Match : RRM_1 (HMM E-Value=7.3e-38) 36 0.47 SB_21661| Best HMM Match : EGF_CA (HMM E-Value=0) 36 0.47 SB_14859| Best HMM Match : SEA (HMM E-Value=0.01) 36 0.47 SB_673| Best HMM Match : VWA (HMM E-Value=8.9e-25) 36 0.47 SB_58882| Best HMM Match : EGF_CA (HMM E-Value=0) 36 0.47 SB_33318| Best HMM Match : EGF (HMM E-Value=7.5e-05) 36 0.47 SB_50933| Best HMM Match : Laminin_EGF (HMM E-Value=0.0069) 36 0.62 SB_17565| Best HMM Match : EGF (HMM E-Value=5.1e-05) 36 0.62 SB_2182| Best HMM Match : EGF_CA (HMM E-Value=0) 36 0.62 SB_38887| Best HMM Match : EGF_CA (HMM E-Value=6.2e-31) 36 0.62 SB_28027| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.62 SB_57938| Best HMM Match : Cadherin (HMM E-Value=0.0027) 35 0.82 SB_42767| Best HMM Match : Thyroglobulin_1 (HMM E-Value=0) 35 0.82 SB_45647| Best HMM Match : HSP70 (HMM E-Value=0) 35 0.82 SB_45586| Best HMM Match : EGF_2 (HMM E-Value=0.00035) 35 0.82 SB_41869| Best HMM Match : Laminin_EGF (HMM E-Value=9.7e-23) 35 0.82 SB_37188| Best HMM Match : Cadherin (HMM E-Value=0.0029) 35 0.82 SB_36925| Best HMM Match : EGF (HMM E-Value=1.5e-16) 35 0.82 SB_7361| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 0.82 SB_58994| Best HMM Match : EGF_CA (HMM E-Value=2.3e-29) 35 1.1 SB_50721| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.1 SB_21681| Best HMM Match : EGF (HMM E-Value=3e-06) 35 1.1 SB_19005| Best HMM Match : EGF (HMM E-Value=1.4e-20) 35 1.1 SB_55591| Best HMM Match : TIL (HMM E-Value=4.2e-09) 35 1.1 SB_47132| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.1 SB_39056| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.1 SB_22868| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.1 SB_22565| Best HMM Match : EGF (HMM E-Value=0.2) 35 1.1 SB_10084| Best HMM Match : Cadherin (HMM E-Value=2.4e-06) 35 1.1 SB_43077| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 1.4 SB_42051| Best HMM Match : EGF_CA (HMM E-Value=6.9e-35) 34 1.4 SB_34212| Best HMM Match : EGF (HMM E-Value=1.1e-05) 34 1.4 SB_29518| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 1.4 SB_24277| Best HMM Match : EGF (HMM E-Value=2.4e-06) 34 1.4 SB_14044| Best HMM Match : EGF_CA (HMM E-Value=4.1e-13) 34 1.4 SB_14014| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 1.4 SB_10438| Best HMM Match : Cadherin (HMM E-Value=0.0027) 34 1.4 SB_9772| Best HMM Match : EGF_CA (HMM E-Value=3.9e-25) 34 1.4 SB_9711| Best HMM Match : EGF (HMM E-Value=2.4e-08) 34 1.4 SB_4259| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 1.4 SB_23241| Best HMM Match : EGF_CA (HMM E-Value=6.3e-30) 34 1.4 SB_58993| Best HMM Match : EGF_CA (HMM E-Value=0) 34 1.9 SB_58780| Best HMM Match : VWA (HMM E-Value=1.3e-34) 34 1.9 SB_52309| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 1.9 SB_51002| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 1.9 SB_43565| Best HMM Match : EGF (HMM E-Value=2.8e-05) 34 1.9 SB_41134| Best HMM Match : EGF_CA (HMM E-Value=0) 34 1.9 SB_35287| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 1.9 SB_13146| Best HMM Match : Laminin_G_2 (HMM E-Value=1.5e-25) 34 1.9 SB_2428| Best HMM Match : ShTK (HMM E-Value=4.2e-21) 34 1.9 SB_55657| Best HMM Match : EGF_CA (HMM E-Value=0) 34 1.9 SB_43823| Best HMM Match : MAM (HMM E-Value=0) 34 1.9 SB_31249| Best HMM Match : PKD (HMM E-Value=4.9) 34 1.9 SB_17530| Best HMM Match : EGF_CA (HMM E-Value=0) 34 1.9 SB_16469| Best HMM Match : EGF (HMM E-Value=4e-09) 34 1.9 SB_6531| Best HMM Match : EGF_2 (HMM E-Value=0.0016) 34 1.9 SB_56885| Best HMM Match : EGF_CA (HMM E-Value=1.1e-08) 33 2.5 SB_46203| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 2.5 SB_45060| Best HMM Match : DSL (HMM E-Value=3e-07) 33 2.5 SB_36177| Best HMM Match : Integrin_beta (HMM E-Value=0) 33 2.5 SB_32816| Best HMM Match : EGF_CA (HMM E-Value=3.1e-11) 33 2.5 SB_53888| Best HMM Match : TSP_3 (HMM E-Value=9.2e-11) 33 2.5 SB_41898| Best HMM Match : EGF_CA (HMM E-Value=3.9e-14) 33 2.5 SB_33267| Best HMM Match : F5_F8_type_C (HMM E-Value=3.4e-10) 33 2.5 SB_19371| Best HMM Match : C_tripleX (HMM E-Value=0.041) 33 2.5 SB_18417| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 2.5 SB_17302| Best HMM Match : Pentaxin (HMM E-Value=1e-09) 33 2.5 SB_1865| Best HMM Match : DUF1168 (HMM E-Value=5) 33 2.5 SB_45154| Best HMM Match : EGF_CA (HMM E-Value=2.8026e-45) 33 3.3 SB_8644| Best HMM Match : 7tm_1 (HMM E-Value=0) 33 3.3 SB_8305| Best HMM Match : Plasmodium_HRP (HMM E-Value=8.8) 33 3.3 SB_5768| Best HMM Match : EGF (HMM E-Value=3.5e-06) 33 3.3 SB_5000| Best HMM Match : EGF_CA (HMM E-Value=0) 33 3.3 SB_1171| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 3.3 SB_58884| Best HMM Match : 7tm_2 (HMM E-Value=2.4e-29) 33 3.3 SB_52354| Best HMM Match : EGF (HMM E-Value=0.0011) 33 3.3 SB_31301| Best HMM Match : EGF (HMM E-Value=0.0037) 33 3.3 SB_29947| Best HMM Match : Fasciclin (HMM E-Value=2.3e-33) 33 3.3 SB_20014| Best HMM Match : EGF_CA (HMM E-Value=1.6e-18) 33 3.3 SB_12383| Best HMM Match : EGF_CA (HMM E-Value=2.5e-12) 33 3.3 SB_10557| Best HMM Match : GCC2_GCC3 (HMM E-Value=7.2e-15) 33 3.3 SB_58945| Best HMM Match : EGF_CA (HMM E-Value=3.6e-06) 33 4.4 SB_49120| Best HMM Match : F5_F8_type_C (HMM E-Value=1.1e-08) 33 4.4 SB_39098| Best HMM Match : EGF (HMM E-Value=5.2e-07) 33 4.4 SB_32896| Best HMM Match : F5_F8_type_C (HMM E-Value=8.6e-17) 33 4.4 SB_31319| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.4 SB_28523| Best HMM Match : EGF (HMM E-Value=2e-05) 33 4.4 SB_27922| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.4 SB_21308| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.4 SB_17959| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.4 SB_10187| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.4 SB_6365| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.4 SB_57056| Best HMM Match : EGF (HMM E-Value=0.13) 33 4.4 SB_53139| Best HMM Match : EGF (HMM E-Value=3.2e-08) 33 4.4 SB_50806| Best HMM Match : EGF_CA (HMM E-Value=1e-27) 33 4.4 SB_42216| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.4 SB_41911| Best HMM Match : PAN (HMM E-Value=0.00033) 33 4.4 SB_36797| Best HMM Match : EGF (HMM E-Value=0.13) 33 4.4 SB_25329| Best HMM Match : EGF (HMM E-Value=0.13) 33 4.4 SB_16758| Best HMM Match : EGF_CA (HMM E-Value=5.5e-14) 33 4.4 SB_14811| Best HMM Match : EGF (HMM E-Value=0.13) 33 4.4 SB_10956| Best HMM Match : EGF (HMM E-Value=5.3e-05) 33 4.4 SB_8486| Best HMM Match : Granulin (HMM E-Value=0) 33 4.4 SB_4118| Best HMM Match : EGF (HMM E-Value=1.8e-20) 33 4.4 SB_48360| Best HMM Match : EGF (HMM E-Value=0.1) 32 5.8 SB_38935| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 5.8 SB_22969| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 5.8 SB_22536| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 5.8 SB_2600| Best HMM Match : Fibrinogen_C (HMM E-Value=0.00053) 32 5.8 SB_52175| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 5.8 SB_32488| Best HMM Match : EGF (HMM E-Value=2) 32 5.8 SB_29723| Best HMM Match : EGF_2 (HMM E-Value=0.55) 32 5.8 SB_28368| Best HMM Match : Pentaxin (HMM E-Value=9.5e-11) 32 5.8 SB_25113| Best HMM Match : EGF (HMM E-Value=9.1e-07) 32 5.8 SB_24499| Best HMM Match : Fibrinogen_C (HMM E-Value=0.00053) 32 5.8 SB_4088| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 5.8 SB_57668| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 7.6 SB_42336| Best HMM Match : Sushi (HMM E-Value=1.5e-08) 32 7.6 SB_30275| Best HMM Match : EGF_CA (HMM E-Value=1.3e-13) 32 7.6 SB_17844| Best HMM Match : Fibrinogen_C (HMM E-Value=0) 32 7.6 SB_9160| Best HMM Match : EGF (HMM E-Value=0.0019) 32 7.6 SB_6741| Best HMM Match : WD40 (HMM E-Value=0) 32 7.6 SB_47980| Best HMM Match : EGF_CA (HMM E-Value=7.6e-20) 32 7.6 SB_40322| Best HMM Match : RVT_1 (HMM E-Value=7.4e-27) 32 7.6 SB_33521| Best HMM Match : Utp14 (HMM E-Value=0.48) 32 7.6 SB_16854| Best HMM Match : UL97 (HMM E-Value=4.9) 32 7.6 >SB_18656| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3292 Score = 614 bits (1517), Expect = e-175 Identities = 367/1115 (32%), Positives = 579/1115 (51%), Gaps = 72/1115 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INVLD ND+ P+FE Y A + E S G VL ++A+D D G N EV+Y I L Sbjct: 337 INVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCI-------L 389 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N + F I SGA+ LDREKV YT+ V+A DQ +P Sbjct: 390 NSDGD-----------NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPR--- 435 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T T+ + ++D ND PQFS+K Y+ ++ ED+ V N ++ ++ATD D G+N + + Sbjct: 436 SATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV--NQLVTTVRATDCDQGSNGEVFFE 493 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ GN FSI+ ++G+V + + LDYE + + L++ AQD G P N T + I + DV Sbjct: 494 IVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDV 553 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP+F +S FQ + EN +G RVQAYD D G N E+T++ D LP + Sbjct: 554 NDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQND------LPFS 607 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G + +LDRE K+ + A D G P + TA F + Sbjct: 608 INENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEE 667 Query: 371 YEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGR-FSITSQNGRGLITVAQP 428 Y +AE+ GT V+ + A D D + Y I + R F I N +GLIT++ Sbjct: 668 YHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRI---NPQGLITLSCT 724 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 L++ + YV +VSA+D G S TA+V +N+TD+N +AP F+ Y+A V EDA +GT+V Sbjct: 725 LNYNTKHVYVFSVSASD-GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSV 783 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L V ATD D G NA+I+YS+++ + +F ++ TG I T LDRE + Y Sbjct: 784 LTVLATDRDTGSNAKISYSIATLVP---------EFSVDETTGVIKTAGSLDREKVDTYR 834 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 VTA D G+P L + V I + DVNDN+PVF + Y A + ED G V +V A+DA Sbjct: 835 FEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDA 894 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D+ N +I Y +G+F ID G+IRT K LDRE++ ++L VA D GTPP Sbjct: 895 DIXKNAQIIYSFASNGDGQGTFTIDRTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQ 954 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 ++V V + +ED+ DSPP+FE + E++P + + ++A D P + YSI Sbjct: 955 ASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVR 1014 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 G+ F + G+ + T++ LDYE+ + +Y L +RA P + + V + + D+N Sbjct: 1015 GNSPQVFDINPNTGA----IQTLMKLDYET-QSEYRLTVRATLSPFFTETTVMVYLKDIN 1069 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848 DN PV++ F + N + P ++PAYD DV+DKL ++++ GN + LN T+G Sbjct: 1070 DNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPDVSDKLTFKVMEGNAKEWVTLNATSGE 1129 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQF 908 ++++ +L K A ++++VTDG+ A + + +T EM+ SI + ++DM +F Sbjct: 1130 LSVNKKL-IQASKPANIKIAVTDGLRTASATGSIMMTSVTTEMIQQSIQLEIDDMEVLEF 1188 Query: 909 LSPLLGFFIDGLAAIIPCPKENIYIFSVQ-------DDTDVTGNILNVSFSARRPDAEVG 961 + + ++ I+ C + + +F + D + L + R+ + + Sbjct: 1189 FNTAYEKLRESVSQIVKCKPDQVLMFDITSRVILPVSSADYSKTRLTIWLVLRKKNEKEA 1248 Query: 962 VAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPC-----LNFEECLTV 1016 G ++ + +R +YLHR +A+ + ++ F D++C +PC ++ +C T Sbjct: 1249 FVG----YFDASFVRYVIYLHREQIAKEVGINLMAFPDDVCSKKPCNYLKPNSYYDCNTY 1304 Query: 1017 LKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 F ++S V+FR + F C CP + G +C+T L C + + + G Sbjct: 1305 TYFSGEPQVLSSLKVVFRTVPVDMKFNCSCPADYRGQDCDTHLN--LCTLTHAATTEKQG 1362 Query: 1077 SQCVARREGGILCQGCSIDAAYTTAVCELRARSFP 1111 C + + G +A T C L+ R P Sbjct: 1363 FYCRCKADR----VGSRCEANVTRDFCPLKPRELP 1393 Score = 367 bits (903), Expect = e-101 Identities = 263/841 (31%), Positives = 412/841 (48%), Gaps = 55/841 (6%) Query: 18 DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77 ++ P F Q +ASV E A GT V T+ A+D D G N + Y+ ++P Sbjct: 236 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYS--------MSPSQNLM 287 Query: 78 XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137 F ID +G + T+ LDRE + R+ VKA D P L + Sbjct: 288 SATY--------FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEP---SLEGYMDLT 336 Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-T 196 +N++D NDN P F Y + ED S+ D + ++A+DAD G+N ++Y I+ + Sbjct: 337 INVLDVNDNGPIFERNIYAADIPEDKSIGD--FVLAVRASDADSGSNGEVKYCILNSDGD 394 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 FSI +SG V+++K LD E+V +Y L ++AQD G+P RS T + I + DVND P+ Sbjct: 395 NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQ 454 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F ++ ++ E+VP+ + V+A D D+G N E+ + + +GN +I+ +G Sbjct: 455 FSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIV----SGNDMNFFSINRING 510 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 V +LD E + LLVTA D G P T F+ ++ + Sbjct: 511 EVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIP 570 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 E+ G + A D+D+ + EIT + + G I++ + LD ++ + Sbjct: 571 ENYAVGQEFYRVQA--YDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPK 628 Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 + + A D G + TA + I + D N+ P F Y S+ E++ GT+VL V A Sbjct: 629 FTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAI 688 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D G + YS+ S + HD+ F INPQ G IT + L+ T Y+ +V+A Sbjct: 689 DPDSG-PTNVVYSIVSS------SGHDRCFRINPQ-GLITLSCTLNYNTKHVYVFSVSAS 740 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 DG LS T V ++V D N + P FK++ Y+A + EDA +GTSV V ATD D G N Sbjct: 741 DG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNA 797 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 +I Y + E F +D +GVI+T +LDRE V T+ + A D G P + V+ Sbjct: 798 KISYSIATLVPE---FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVY 854 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSN 733 I I D+ND+ PVF + E+ G + E+ A D D NA + YS GD Sbjct: 855 IHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIXKNAQIIYSFASNGDGQG 914 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790 +F+++ QG + T+ LD E+ +YEL + A +PP V+V++++ DV D+ Sbjct: 915 TFTIDRTQGI----IRTLKPLDRET-IPEYELTVVATDQGTPPGQASVKVKVILEDVKDS 969 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGS 848 P+ + +D P P V A D++ + + Y I+ GN+ + +N TG+ Sbjct: 970 PPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGA 1029 Query: 849 M 849 + Sbjct: 1030 I 1030 Score = 310 bits (761), Expect = 1e-83 Identities = 256/826 (30%), Positives = 375/826 (45%), Gaps = 59/826 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN----- 144 +R+D ++G L+ R SL R +V Q+S S R S A + + I D Sbjct: 168 YRVDSKTGHLVLRKSLVGHP-ERIMFVVAQLSQSSKNSKRKKS-ARLRLFIDDGKQIKNN 225 Query: 145 ----------DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 +N PQFS SV ED V V+A + A+D D G+N IRY++ Sbjct: 226 RRRVRKRAPTNNPPQFSRLQEDASVSEDAEV--GTVVATVSASDPDSGSNGMIRYSMSPS 283 Query: 195 NTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 M FSID ++G ++ + LD E + + ++A+DGG PS L IN+ DVN Sbjct: 284 QNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVN 343 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P F +++ + E+ IG ++ V+A DAD G N E+ Y + + D + +I Sbjct: 344 DNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSA---FSI 400 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 SG V +LDRE Y L V A D G+PPRSAT T F Y Sbjct: 401 GEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVY 460 Query: 372 EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + ED P V T+ ATD D+ + + +EI GN FSI NG + V Q L Sbjct: 461 SATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGE--VRVKQKL 518 Query: 430 DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D++ + L V+A D G + V I + D N+ AP F ++ + + E+ +G Sbjct: 519 DYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQE 578 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V A D D G N +IT+S +D F IN TG I+ + LDRE + + Sbjct: 579 FYRVQAYDKDHGTNGEITFSF---------MQNDLPFSINENTGGISIKEELDREKVPKF 629 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 + ARD GVP T + I+++D+NDN P F Q+ Y +I E++ GTSV QV A D Sbjct: 630 TFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAID 689 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G + Y + + F I+P G+I + L+ + + A DG Sbjct: 690 PDSGPT-NVVYSIVSSSGHDRCFRINP-QGLITLSCTLNYNTKHVYVFSVSASDG---ML 744 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 SST +V++ + D N P F+ + + E++ +GT++ + A D D G NA + YSI Sbjct: 745 SSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI- 803 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILV 784 FS++ G K T LD E Y + A P L V I + Sbjct: 804 -ATLVPEFSVDETTGVIK----TAGSLDREKV-DTYRFEVTATDHGIPQLKAKSFVYIHI 857 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ--YRILS-GNNANLIL 841 DVNDN PV +D P G V A DAD+ Q Y S G+ Sbjct: 858 ADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIXKNAQIIYSFASNGDGQGTFT 917 Query: 842 LNETTGSM-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 ++ T G + TL P +P+ V+ G +A +++ V L Sbjct: 918 IDRTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVIL 963 Score = 284 bits (697), Expect = 6e-76 Identities = 215/708 (30%), Positives = 337/708 (47%), Gaps = 48/708 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +LD ND +P F + Y A++RE V T++ATD D G N EV + E+V+ + Sbjct: 442 KITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFF--EIVSGND 499 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +N F I+ +G + + LD E + + +LV A D+ P Sbjct: 500 MN-----------------FFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPF--- 539 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + T+ + +ID NDN PQF + + E+ +V +++A D D G N I + Sbjct: 540 LYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQE--FYRVQAYDKDHGTNGEITF 597 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + + + FSI+ +G +S+ + LD E+V + I+A+D G P + T Q+ I + D Sbjct: 598 SFM--QNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLD 655 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P+F + S++EN G S+++V+A D D G + Y++ +G+ D Sbjct: 656 INDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG-PTNVVYSIVSS--SGH-DRCF 711 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+P+ G + S L+ T+ Y V+A+DG S+TA F Sbjct: 712 RINPQ-GLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRR 767 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y E+ ED GT V+T+ ATD D + + FS+ G+I A L Sbjct: 768 SYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETT--GVIKTAGSL 825 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D ++ Y V+ATD G + V I+I D N+ PVF Y A V ED G Sbjct: 826 DREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGR 885 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V+ VSA+D+D+ NAQI YS +S + F I+ G I T K LDRET+ Y Sbjct: 886 VIEVSASDADIXKNAQIIYSFASNGDGQGT------FTIDRTQGIIRTLKPLDRETIPEY 939 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LTV A D G P + V++ + DV D+ P+F++ LY + ED + V V A Sbjct: 940 ELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKS 999 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D+ + Y + + F I+P +G I+T LD E+ + + L + P Sbjct: 1000 QDLSPETGMMYSI-VRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRL---TVRATLSPF 1055 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 + V + ++DIND+ PV E+ + + E +I A+DPD Sbjct: 1056 FTETTVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPD 1103 Score = 272 bits (666), Expect = 3e-72 Identities = 164/577 (28%), Positives = 266/577 (46%), Gaps = 47/577 (8%) Query: 1357 RFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKS---------GLLHYSYN 1407 RF G +L N I+LPW +L RTR+ ++ + +S G L Y +N Sbjct: 1744 RFIGQSILIKNYRTTSIKLPWSQSLMFRTRKSLGILIETRFRSSAGVLKVVNGRLSYQFN 1803 Query: 1408 GE-TMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466 + T+ L + DGAWH +++ WL + VT DY + K++ + ++++G Sbjct: 1804 QQLTVNLSQLRVDDGAWHHVDVTWLRGMVRVTGDYIYQATATHQ-GEKLE--FTSELIMG 1860 Query: 1467 G---LDTTAGLLASDVGF-FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSIC 1522 G L+T+A + + F GC+ + + +Q ++ T +++V GC + C S C Sbjct: 1861 GRQSLNTSAPQPKAYIEEGFVGCMMGITVDGSQIDTSQAT-KQSVFTGCSMPSHCQSSPC 1919 Query: 1523 PPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARC-VPDQTPKGYSCACEPGYTL 1581 CV WD+ +C C G VG +C + C+L PC C + TPKGY C C P YT Sbjct: 1920 LGGGTCVEGWDTFSCRCRPGYVGKRCTNVCDLKPCQNGNCELSSATPKGYKCKCPPQYT- 1978 Query: 1582 TTSGCIESGKEECPGGWWGGS---ACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638 C + C ++ S CGPC C V ++P CNK G+C+C HY+ Sbjct: 1979 -GEYCETRKETPCQDKFFSASNIGLCGPCNCPVGANFNPVCNKTTGECYCNPYHYRSPKG 2037 Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCP 1698 ECL C C GS + C + GQC C G V+ CP Sbjct: 2038 NECLKCNCEEIGSLSLQCRVSDGQCPCIKG--------------------SSTVINTSCP 2077 Query: 1699 RSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRK 1758 RS A +WW R F CP G+SG A R CD+ K WQ PD+ +C + +F LRK Sbjct: 2078 RSIAEDIWWKRGAFDKIAEQKCPFGASGTARRICDKNKG--WQKPDLMDCVSNSFLNLRK 2135 Query: 1759 QLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLN 1818 +L ++E G+L + + + +A L A RLY D+ +A + L DYE +Q Sbjct: 2136 KLKRLEEGKLLWSPSIAMDLARQLDLAITLATRLYPNDIDIALKAITVLFDYESQQNEST 2195 Query: 1819 LTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQHD 1878 L +++ ++ + L++S + + N E + W ++ + A+L+ +K + + LA + Sbjct: 2196 LVSAKNHEFAQILVQSASMLFNAENKNVWSVVQRNSAGTADLM-EKMENFSGTLANNLAH 2254 Query: 1879 TYTSPFEIVTKDVVISVDTVTSESIYGFEPTQLNRLN 1915 + + + ++ +T + P + N Sbjct: 2255 LKRARYRRNVESIIPPYTVITPNILMELHPVTIRNFN 2291 Score = 241 bits (589), Expect = 7e-63 Identities = 200/724 (27%), Positives = 336/724 (46%), Gaps = 62/724 (8%) Query: 4 PFCIHQ---QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 PF +Q I ++D ND++P F ++ + E + G ++A D+D G N E+ Sbjct: 538 PFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEI-- 595 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 T + D F I+ +G + + LDREKV ++T +KA Sbjct: 596 TFSFMQNDL-------------------PFSINENTGGISIKEELDREKVPKFTFGIKAR 636 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 D+ P + TA I + ++D NDN P+FS++ Y S+ E+ + + ++KA D D Sbjct: 637 DKGVPFKE---GTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTS--VLQVKAIDPD 691 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 G + + Y+I+ + + + G ++L TL+Y Y + A DG S+T Sbjct: 692 SGPTNVV-YSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDG---MLSST 747 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + +N+ D N +AP F + V E+ +G S++ V A D D G NA+++Y++ Sbjct: 748 ALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI---- 803 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + ++D +G + T+G LDRE Y+ VTATD G P A + Sbjct: 804 --ATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVN 861 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418 F+ YE ++ ED PG V+ ++A+DAD ++ ++ Y N G+ + T Sbjct: 862 DNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIXKNAQIIYSF-ASNGDGQGTFTIDR 920 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTA 476 +G+I +PLD + Y LTV ATD G A V++ + D + P+FE Y Sbjct: 921 TQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEV 980 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 +V ED P + V+ V A D+ + YS+ + Q F INP TGAI T Sbjct: 981 TVPEDTPPRSPVITVKAKSQDLSPETGMMYSI-------VRGNSPQVFDINPNTGAIQTL 1033 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LD ET S Y LTV A P ++TT V + + D+NDN PV + N+ E + Sbjct: 1034 MKLDYETQSEYRLTVRATLS--PFFTETT-VMVYLKDINDNTPVLEAFHMNINVQEGKVP 1090 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 + ++ A D DV + ++ +++ + +E ++ SG + NK L + S ++K Sbjct: 1091 PEARYKIPAYDPDV--SDKLTFKVMEGNAKEW-VTLNATSGELSVNKKLIQASKPA-NIK 1146 Query: 657 AVAIDG--GTPPQSSTVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAH 712 DG S ++ + E I S + + + L F+ + + ++ +I Sbjct: 1147 IAVTDGLRTASATGSIMMTSVTTEMIQQSIQLEIDDMEVLEFFNTAYEKLRESVSQIVKC 1206 Query: 713 DPDE 716 PD+ Sbjct: 1207 KPDQ 1210 Score = 239 bits (585), Expect = 2e-62 Identities = 159/432 (36%), Positives = 222/432 (51%), Gaps = 21/432 (4%) Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N P F ASV EDA +GT V VSA+D D G N I YS+S + + + Sbjct: 236 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATY---- 291 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F I+ TG ITT + LDRE + + V A DGG PSL D+ I+V+DVNDN P+F++ Sbjct: 292 FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFER 351 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 +Y A+I ED +G V V A+DAD G NG + Y + D + +F I SG + K Sbjct: 352 NIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMK 411 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 LDRE V T+ L+ A D G PP+S+TV V I + D+ND P F + I E+ P+ Sbjct: 412 KLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVN 471 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + +RA D D+G N V + I G+D N FS+ G E+ LDYE + Sbjct: 472 QLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRING----EVRVKQKLDYEM-IGVF 526 Query: 764 ELVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVG-PFGRVP 817 L++ A P L+N V+I + DVNDNAP V FQ + + + VG F RV Sbjct: 527 NLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMI---PENYAVGQEFYRVQ 583 Query: 818 AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTD-GVNE 875 AYD D + N +NE TG +++ +L+ VPK T + D GV Sbjct: 584 AYDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPKF-TFGIKARDKGVPF 642 Query: 876 IKAMMQLSVRLI 887 + Q+++ L+ Sbjct: 643 KEGTAQITITLL 654 Score = 237 bits (581), Expect = 7e-62 Identities = 205/712 (28%), Positives = 312/712 (43%), Gaps = 34/712 (4%) Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 K D+ G + +R +++G ++ F + LS K ++ RL I D Sbjct: 166 KFYRVDSKTG-HLVLRKSLVGHPERIMFVVAQLSQSS---KNSKRKKSARLRLFI---DD 218 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 G ++N + + R +N P+F SVSE+ +G + V A D D G N + Sbjct: 219 GKQIKNNRRR--VRKRAPTNNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMI 276 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y+M+ + +ID +G + T LDRE ++ V A DGG+P Sbjct: 277 RYSMSPSQNLMSATY-FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDL 335 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412 F Y ++ ED+ G V+ + A+DAD + + N+ G Sbjct: 336 TINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDN 395 Query: 413 SITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469 S S G +TV + LD ++ Y L V A D G RS T V+I + D N+ P F Sbjct: 396 SAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQF 455 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INP 528 Y+A++ ED P+ V V ATD D G N ++ + E V+ +D F IN Sbjct: 456 SKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFF--------EIVSGNDMNFFSINR 507 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 G + + LD E + + L VTA+D G P L + T V+I+++DVNDN P F + Sbjct: 508 INGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQT 567 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 I E+ VG +V A D D G NG I + D F I+ +G I + LDRE Sbjct: 568 MIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDL---PFSINENTGGISIKEELDRE 624 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 V A D G P + T + I + DIND+PP F + I+ENS GT++ + Sbjct: 625 KVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQ 684 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVI 767 ++A DPD GP VV+ + F + QG L+T+ L+Y + + Y + Sbjct: 685 VKAIDPDSGPTNVVYSIVSSSGHDRCFRINP-QG-----LITLSCTLNYNT-KHVYVFSV 737 Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827 A+ L + V + VTD N +AP K +D V A D D Sbjct: 738 SASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNA 797 Query: 828 QYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878 + ++ETTG + + L+ EV+ TD G+ ++KA Sbjct: 798 KISYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKA 849 Score = 181 bits (441), Expect = 6e-45 Identities = 107/321 (33%), Positives = 159/321 (49%), Gaps = 37/321 (11%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDG---------DGSICRSGSQCVARREGGILCQGC 1092 F C+C G CE +T+ C + + C +G+QC+ + GG C C Sbjct: 1363 FYCRCKADRVGSRCEANVTRDFCPLKPRELPKVNQMKWNPCMNGAQCINQPGGGFGCL-C 1421 Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERH 1152 T CEL SF + F L ++ R+H+ L+F T + LLLYNG++N++ Sbjct: 1422 EDSNKADTPFCELTTLSFRDGDYAAFTALSQKWRLHISLQFTTLQSDALLLYNGQFNDKQ 1481 Query: 1153 DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTITM 1210 DF+A+EL G +RF+ S GG + T V+G + DG WH++ Y N+T + Sbjct: 1482 DFIAIEL--------SGGQVRFTVSTGGTPASATSRVDGGLNDGRWHSLTAVYKNKTAIV 1533 Query: 1211 ILDDCDKVLSLAGAADFGLK---YACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGL 1267 I+DDC LA A FG + Y CA R + R L LT PL +GGL Sbjct: 1534 IIDDC----KLAVAVQFGTQEGSYGCAAAKRL---------NQQAARSLQLTSPLMLGGL 1580 Query: 1268 PNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAE 1327 ++ S + + +K + GC+ + IDHK +DL + + GT C K C ++PC G Sbjct: 1581 HSLRSEYPITSKRYTGCLRNVSIDHKRLDLAAPIWKRGTSPKCSIKVDFCRNSPCKRG-N 1639 Query: 1328 CSDLWDTYICDCKEGHTGKDC 1348 C++ W TY+C C E + GK C Sbjct: 1640 CTNTWGTYLCRCPENYGGKQC 1660 Score = 75.4 bits (177), Expect = 6e-13 Identities = 51/171 (29%), Positives = 94/171 (54%), Gaps = 21/171 (12%) Query: 2159 NATGVGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWS----TLRGSGEWS 2214 N+ V KM + ++L +PI + + NR+ +R+ CV W+ RG G WS Sbjct: 2367 NSDVVSVKM-PGMEDVQLAEPIHITFY---NRQV--NRSEYLCVFWNYSVPNTRGGG-WS 2419 Query: 2215 RVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFS 2274 GC I +W+ + C CNH+++FAVL D +++EF P+ + + +Y + Sbjct: 2420 TNGCR-RIAINWTHTT-------CACNHMTSFAVLSD-LNLEFPPQVAFALRIGTYIGIA 2470 Query: 2275 ISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTS 2325 +S+ +LL ++ + +RG + +N IHK+L+ ++ +AE+++L + RTS Sbjct: 2471 VSVAILLIAFVSFVCLRGLKKSNANDIHKNLVAAIVIAEIIFLAGIN-RTS 2520 Score = 62.5 bits (145), Expect = 5e-09 Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 1256 LDLTGPLQIGGLPNIPSSF-QVK---NKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCP 1311 L+ T L +GG ++ +S Q K + FVGC+ +D ID S GC Sbjct: 1851 LEFTSELIMGGRQSLNTSAPQPKAYIEEGFVGCMMGITVDGSQID-TSQATKQSVFTGC- 1908 Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 S C S+PC G C + WDT+ C C+ G+ GK C + Sbjct: 1909 SMPSHCQSSPCLGGGTCVEGWDTFSCRCRPGYVGKRCTN 1947 Score = 36.3 bits (80), Expect = 0.35 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 1458 QYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRAD- 1516 Q +++GGL + + GC+++V I + L P + C + D Sbjct: 1570 QLTSPLMLGGLHSLRSEYPITSKRYTGCLRNVSIDHKRLDLAAPIWKRGTSPKCSIKVDF 1629 Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548 C S C C +W + C C G QC Sbjct: 1630 CRNSPC-KRGNCTNTWGTYLCRCPENYGGKQC 1660 >SB_22798| Best HMM Match : Cadherin (HMM E-Value=0) Length = 3255 Score = 434 bits (1069), Expect = e-121 Identities = 291/825 (35%), Positives = 426/825 (51%), Gaps = 55/825 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ P F Y +V E ++G V + ATD D G N ++ Y+I Sbjct: 891 KVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSI------- 943 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ + F +D +G + TR LDRE +A Y++ + A D S V R Sbjct: 944 LSGNENMA------------FAMDRFTGEITTRVPLDRETIASYSLTINA-DDGSLV--R 988 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T++++I D+NDN P F+ + ++ ED S T V ++ ATD D+G N A+ Y Sbjct: 989 FMAATTVNISIADENDNQPTFTGPS-RFNISED-SPTGTRV-GQLTATDRDIGPNGAVTY 1045 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 AII GN F +D SG +S+ TLD E + SY LV++A D GSP +S T + +++ D Sbjct: 1046 AIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLD 1105 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAPRF SLF + E+ + ++++V+ D DEG N +T ++ +G Sbjct: 1106 VNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL-----SGEGSDNF 1160 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 TID +G+V + LD ET A YQL VTA DGG P +SATA F+ Sbjct: 1161 TID-STGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSP 1219 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + ED T VV L ATD+D L ++I GN F I + GLI+VA+ L Sbjct: 1220 AQVTSIPEDVAINTHVVKLNATDSD-GTPLTFDIVEGNAGSSFKIDQSS--GLISVAKRL 1276 Query: 430 DFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + Y L V AT++G + ++ I + D N+ APVF Y S+ E+ PIG T Sbjct: 1277 DRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQT 1336 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V V+ATD D G NA++TY LS +F +NP TG +TT + LDRE + Y Sbjct: 1337 VAKVTATDRDEGENAKVTYELS--------VGDTSKFEVNPATGLVTTKRPLDREDQASY 1388 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 L VTA D G PS S + +++ D+NDN P F Q YT + E+ G+++ +V A+D Sbjct: 1389 SLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASD 1448 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G NGR+ Y + +F ID +G I +DRE++A+++L A D G PP Sbjct: 1449 PDAGANGRVTYSI-ISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPW 1507 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 ST V I + D ND+ P+F S+ ++ I E IG+ + + A D DEG NA V YSI Sbjct: 1508 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV 1567 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVEILVTD 786 GD S +F++ G L +++ E+ P + Y +R S + + V +D Sbjct: 1568 RGDTS-AFAINAMNG----VLTVKKEINRETVPTQSYIGSVRENSAQSTSVLTVAADDSD 1622 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRV--PAYDADVTDKLQY 829 V NA V++ + II N + F + V D +K QY Sbjct: 1623 VGANA-VLR-YSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQY 1665 Score = 420 bits (1034), Expect = e-117 Identities = 285/788 (36%), Positives = 394/788 (50%), Gaps = 77/788 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P F + Y+ V E + G+ V L A D D+G NA + Y+ LV+ DT Sbjct: 396 KITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYS--LVSGDT 453 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F +D + G + T+ + DRE A Y V ++A D SP Sbjct: 454 ------------------SYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSP---S 491 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S AT+ + I+D NDN P FS YT SVDED+++ + + A+D D G N+ +RY Sbjct: 492 RSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAI--GAAMVTVTASDKDNGNNADLRY 549 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + GNT F++D+++G V++ ++LD+EQ SY L + D GSP ++T+ LLIN+ D Sbjct: 550 SFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVND 609 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P F S +Q V EN P G +V A D D N L + + GN D Sbjct: 610 INDNPPVFSPSAYQSRVKENTPAG---TQVSATDRDSSTNGALVFGI----IKGNDDGVF 662 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 TID +G + + D E + +Y L V A D G P + TA F P Sbjct: 663 TIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPS 722 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y ++ E G+ VVTLTATD D RG I V+ L Sbjct: 723 NYSKQIPESTVIGSTVVTLTATDLD----------------------SGPRGSIRVSSEL 760 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + Y L V A D G RS + V I + D N+ +P+F+ PY V E + G Sbjct: 761 DRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQ-GPYVFRVSESSSPGHQ 819 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 + V+ATD+D N + Y+LS + F IN TG IT LD E + Y Sbjct: 820 IGQVAATDADDSSNGDVRYALSD---------NTDVFSINTSTGLITLKTQLDYEKKTQY 870 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 ++TVTA+DGG PS S T V++ V DVNDN P F + LYT + E+ G +V V ATD Sbjct: 871 MVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATD 930 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 AD G NG+I Y + E +F +D +G I T LDRE++A++ L A DG Sbjct: 931 ADSGANGKISYSI-LSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRF 989 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 + V+I I D ND+ P F F ISE+SP GT +G++ A D D GPN V Y+I Sbjct: 990 MAATTVNISIADENDNQPTFTGPS-RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAII 1048 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784 G+ NSF L+ R G L LD E+ Y LV++A+ SP + + V Sbjct: 1049 SGNQGNSFQLDPRSGI----LSVRSTLDRET-IPSYTLVVKASDAGSPQQSITASIHVSV 1103 Query: 785 TDVNDNAP 792 DVNDNAP Sbjct: 1104 LDVNDNAP 1111 Score = 410 bits (1009), Expect = e-113 Identities = 276/867 (31%), Positives = 439/867 (50%), Gaps = 78/867 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +LD ND+ PVF QY ASV E + G ++T+ A+D+D G NA++ Y+ T+ Sbjct: 499 EIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSF---TSGN 555 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N F +D +G + SLD E+ + Y + + TD+ SP Sbjct: 556 TN----------------HAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSP---P 596 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+ T+ + +N+ D NDN P FS Y V E + P ++ ATD D N A+ + Sbjct: 597 LTDTSHLLINVNDINDNPPVFSPSAYQSRVKE-----NTPAGTQVSATDRDSSTNGALVF 651 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 II GN F+ID +G +S+ K+ DYE Y L ++A+D G P + +T Q+ I I D Sbjct: 652 GIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIED 711 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VND++P F S + + + E+ IG ++V + A D D G Sbjct: 712 VNDHSPVFSPSNYSKQIPESTVIGSTVVTLTATDLDSG---------------------- 749 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 PR G + S +LDRET Y L V A DGG RS++ F G Sbjct: 750 ---PR-GSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQ-G 804 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y ++E PG + + ATDAD+ + + FSI + GLIT+ L Sbjct: 805 PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTST--GLITLKTQL 862 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D++++ +Y++TV+A D G RS +V++ + D N+ P F + YT +V E+ G Sbjct: 863 DYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVA 922 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V V+ATD+D G N +I+YS+ S NE +A F ++ TG ITT LDRET++ Y Sbjct: 923 VCYVTATDADSGANGKISYSILS--GNENMA-----FAMDRFTGEITTRVPLDRETIASY 975 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LT+ A DG + T V IS+ D NDN+P F NI ED+ GT V Q+ ATD Sbjct: 976 SLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP-SRFNISEDSPTGTRVGQLTATD 1034 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D+G NG + Y + + SF +DP SG++ LDRE++ ++ L A D G+P Q Sbjct: 1035 RDIGPNGAVTYAI-ISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQ 1093 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 S T +H+ + D+ND+ P FE + I E++ + +T+ +++ D DEG N + S+ Sbjct: 1094 SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL- 1152 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784 G+ S++F++++ +++ LDYE+ Y+L + A SP +V+I + Sbjct: 1153 SGEGSDNFTIDS-----TGFVLSKTPLDYET-TAAYQLTVTARDGGSPSKSATAQVKITI 1206 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844 +VNDN P + + +D ++ A D+D T L + I+ GN + +++ Sbjct: 1207 INVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGT-PLTFDIVEGNAGSSFKIDQ 1265 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++G ++++ +L+ T+ V T+ Sbjct: 1266 SSGLISVAKRLDRETTANYTLVVRATE 1292 Score = 380 bits (934), Expect = e-104 Identities = 262/767 (34%), Positives = 393/767 (51%), Gaps = 43/767 (5%) Query: 94 GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEK 153 G G++ + LDRE Y++ V+A D S + R SST + + + D NDN P F + Sbjct: 749 GPRGSIRVSSELDRETTPSYSLQVEARDGGS--TSRSSSTR-VTIALQDINDNSPIF-QG 804 Query: 154 TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213 Y V E S + I ++ ATDAD +N +RYA+ NT + FSI++ +G ++L Sbjct: 805 PYVFRVSE--SSSPGHQIGQVAATDADDSSNGDVRYAL-SDNTDV-FSINTSTGLITLKT 860 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273 LDYE+ Y + + A+DGG+PSRS+ T + + + DVNDN P+F SL+ +V EN+ G Sbjct: 861 QLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAG 920 Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333 ++ V A DAD G N +++Y++ +GN ++ +D +G + T LDRET A Y Sbjct: 921 VAVCYVTATDADSGANGKISYSI----LSGNENMAFAMDRFTGEITTRVPLDRETIASYS 976 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 L + A D G R AT G ++ED P GT V LTATD Sbjct: 977 LTINA-DDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTRVGQLTATDR 1035 Query: 394 D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--R 449 D + + Y I GN F + ++ G+++V LD + Y L V A+D+G + Sbjct: 1036 DIGPNGAVTYAIISGNQGNSFQLDPRS--GILSVRSTLDRETIPSYTLVVKASDAGSPQQ 1093 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 S TA + +++ D N+ AP FE + ++ + EDA + +TVL V D D G N IT SLS Sbjct: 1094 SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLS 1153 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 E S+ F I+ TG + + LD ET + Y LTVTARDGG PS S T V+I Sbjct: 1154 GEGSD--------NFTID-STGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKI 1204 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 ++++VNDN P F +I ED + T V ++ ATD+D + +++ + S Sbjct: 1205 TIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD---GTPLTFDI-VEGNAGSS 1260 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F ID +SG+I K LDRE+ A + L A + G+ +S I++ D+ND+ PVF Sbjct: 1261 FKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNP 1320 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 + EN PIG T+ ++ A D DEG NA V Y + GD S F + G + Sbjct: 1321 GSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTS-KFEVNPATGL----VT 1375 Query: 750 TMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 T LD E + Y L + A P + + + D+NDN+P + ++ Sbjct: 1376 TKRPLDRED-QASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTEN 1434 Query: 807 CFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL 851 RV A D D ++ Y I+SGN+ N ++ TTG +T+ Sbjct: 1435 TANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITV 1481 Score = 350 bits (861), Expect = 8e-96 Identities = 277/877 (31%), Positives = 428/877 (48%), Gaps = 102/877 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND++P F + Y ++RE + + + ATD+D G NA + Y++ Sbjct: 195 IDVKDENDNAPEFPLNSYVFNIRENTPAAQVAI-VTATDRDSGTNAAITYSL-------- 245 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++ F ++ ++G + T LD E YT+ + A D + Sbjct: 246 -------------FSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFD------GKH 286 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGANSA 186 ++ + +NI+D N+ P+F + T D +V + N I + ATD D + Sbjct: 287 TTFVPLVINILDVNEP-PRFQDDC-TRRGDCSATVLESAPLNTRIVTLAATDPD---GDS 341 Query: 187 IRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + Y++ I + + F+ID+ SG ++L K LD E +Y LV+ A DG + L I Sbjct: 342 LLYSVRIRDSQEKIFTIDN-SGRLTLNKMLDREAKSAYDLVVEASDGNIIA---IAALKI 397 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVNDNAP F S+++ V E+V +G + ++ A D D G+NA L+Y++ D + Sbjct: 398 TVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSY-- 455 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 T+D + G + T G DRET+A YQ+ + A DGG P RS AT Sbjct: 456 ---FTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPV 511 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLI 423 F QY + ED G +VT+TA+D D N L Y T GNT F++ + G ++ Sbjct: 512 FSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTG--VV 569 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481 TV++ LDF+Q Y L +S TD G +DT+ + IN+ D N+ PVF + Y + V E+ Sbjct: 570 TVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKEN 629 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P GT V SATD D N + + + + D F I+ TG I+ K D Sbjct: 630 TPAGTQV---SATDRDSSTNGALVFGIIK-------GNDDGVFTIDGSTGIISIAKSPDY 679 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E + Y LTV ARD GVP DT V I + DVND+ PVF Y+ I E ++G++V Sbjct: 680 ENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVV 739 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + ATD D G P+ G IR + LDRE+ ++ L+ A D Sbjct: 740 TLTATDLDSG----------PR-------------GSIRVSSELDRETTPSYSLQVEARD 776 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 GG+ +SS+ V I ++DIND+ P+F+ + F +SE+S G IG++ A D D+ N Sbjct: 777 GGSTSRSSSTRVTIALQDINDNSPIFQGPYV-FRVSESSSPGHQIGQVAATDADDSSNGD 835 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRA---ASPPLWND 777 V Y++ D+++ FS+ T G L+T+ LDYE + +Y + + A +P + Sbjct: 836 VRYALS--DNTDVFSINTSTG-----LITLKTQLDYEK-KTQYMVTVTAKDGGTPSRSSL 887 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGN 835 V+++V DVNDN P ++ V A DAD K+ Y ILSGN Sbjct: 888 TVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGN 947 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++ TG +T L+ ++ ++ DG Sbjct: 948 ENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDG 984 Score = 347 bits (853), Expect = 8e-95 Identities = 274/877 (31%), Positives = 417/877 (47%), Gaps = 95/877 (10%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H INV D ND+ PVF Y++ V+E +GT V ATD+D N + + I Sbjct: 602 HLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQV---SATDRDSSTNGALVFGI----- 653 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 + D VF IDG +G + S D E RY + V+A D+ PV Sbjct: 654 --IKGND------------DGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVK 699 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 TA + + I D ND+ P FS Y+ + E S + + ATD D G +I Sbjct: 700 ---YDTAQVTIFIEDVNDHSPVFSPSNYSKQIPE--STVIGSTVVTLTATDLDSGPRGSI 754 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 R + LD E SY L + A+DGGS SRS++T++ I + Sbjct: 755 RVS----------------------SELDRETTPSYSLQVEARDGGSTSRSSSTRVTIAL 792 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 +D+NDN+P + + VSE+ G+ I +V A DAD+ N ++ Y ++D N D+ Sbjct: 793 QDINDNSP-IFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSD-----NTDV 846 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +I+ +G + QLD E + +Y + VTA DGG P RS+ F Sbjct: 847 -FSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFA 905 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ G V +TATDAD + ++ Y I GN F++ G IT Sbjct: 906 KSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGE--ITT 963 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 PLD + Y LT++A D V I+I D N+ P F P ++ ED+P Sbjct: 964 RVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTF-TGPSRFNISEDSP 1022 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT V ++ATD D+G N +TY++ S + F ++P++G ++ LDRET Sbjct: 1023 TGTRVGQLTATDRDIGPNGAVTYAIIS-------GNQGNSFQLDPRSGILSVRSTLDRET 1075 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y L V A D G P S T + +SV+DVNDN P F++ L++ I EDA V ++V QV Sbjct: 1076 IPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQV 1135 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D D G NG I L + + +F ID ++G + + LD E+ A + L A DGG Sbjct: 1136 KVEDKDEGSNGAITLSLSGEGSD--NFTID-STGFVLSKTPLDYETTAAYQLTVTARDGG 1192 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 +P +S+T V I I ++ND+ P F S I E+ I T + ++ A D D P + Sbjct: 1193 SPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTP---LT 1249 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAA-----SPPLWND 777 + I G+ +SF ++ G L+++ LD E+ Y LV+RA ++N+ Sbjct: 1250 FDIVEGNAGSSFKIDQSSG-----LISVAKRLDRET-TANYTLVVRATETGSQGESVYNN 1303 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSG 834 + +L DVNDNAPV + +++ P+G +V A D D + K+ Y + G Sbjct: 1304 ATIRVL--DVNDNAPVFNPGSYAKSLHEN-LPIGQTVAKVTATDRDEGENAKVTYELSVG 1360 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + +N TG +T L+ ++ V+ D Sbjct: 1361 DTSK-FEVNPATGLVTTKRPLDREDQASYSLRVTAMD 1396 Score = 325 bits (799), Expect = 3e-88 Identities = 256/799 (32%), Positives = 387/799 (48%), Gaps = 78/799 (9%) Query: 87 QDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 Q +F ID +G++ T DRE +RY + V A D A+ + +++ D+ND Sbjct: 146 QGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCH---KGRTVVVIDVKDEND 202 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P+F +Y ++ E+ T +A + ATD D G N+AI Y++ G + F ++S Sbjct: 203 NAPEFPLNSYVFNIREN---TPAAQVAIVTATDRDSGTNAAITYSLFSGENK--FMMNSK 257 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE- 264 +G++ V LD+E SY + I A DG + L+INI DVN+ PRF + Sbjct: 258 TGEIRTVTPLDHETKDSYTMRISAFDG---KHTTFVPLVINILDVNE-PPRFQDDCTRRG 313 Query: 265 ----SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 +V E+ P+ IV + A D D L Y++ +D + TID SG + Sbjct: 314 DCSATVLESAPLNTRIVTLAATDPD---GDSLLYSVRIRDSQEKI---FTID-NSGRLTL 366 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 + LDRE ++ Y L+V A+DG A A F Y+ + ED Sbjct: 367 NKMLDREAKSAYDLVVEASDGNI---IAIAALKITVDDVNDNAPFFALSVYKTGVYEDVA 423 Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 G+ V LTA D D + RL Y + G+T F++ SQ G+I D + + Y Sbjct: 424 VGSIVRQLTAVDLDVGINARLSYSLVSGDT-SYFTVDSQ---GVIRTKGAFDRETKASYQ 479 Query: 439 LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 + + A D G RS A V+I I D N+ PVF +A YTASV ED IG ++ V+A+D Sbjct: 480 VALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDK 539 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G NA + YS +S +N A F ++ TG +T ++ LD E S Y L ++ D Sbjct: 540 DNGNNADLRYSFTSGNTNHA-------FTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDR 592 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P L+DT+ + I+V D+NDN PVF Y + + E+ GT QV ATD D NG + Sbjct: 593 GSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGAL 649 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 + + K ++G F ID ++G+I K+ D E+ +DL A D G P + T V I Sbjct: 650 VFGII-KGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIF 708 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGDDSNSF 735 IED+ND PVF + I E++ IG+T+ + A D D GP + S + + + S+ Sbjct: 709 IEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTLTATDLDSGPRGSIRVSSELDRETTPSY 768 Query: 736 SL--ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793 SL E R G + R++S RV I + D+NDN+P+ Sbjct: 769 SLQVEARDGGSTS---------------------RSSS------TRVTIALQDINDNSPI 801 Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853 + +F + P G+V A DAD + R +N ++ +N +TG +TL Sbjct: 802 FQG-PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKT 860 Query: 854 QLNTNVPKLATMEVSVTDG 872 QL+ + V+ DG Sbjct: 861 QLDYEKKTQYMVTVTAKDG 879 Score = 308 bits (755), Expect = 6e-83 Identities = 202/649 (31%), Positives = 328/649 (50%), Gaps = 41/649 (6%) Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F++ +Y+ SV E++ T N + + V N +RY+I+ GN Q F+IDS +G + Sbjct: 106 FAKDSYSASVKEELQATQNVI-----TVSSSVSPN--LRYSIMDGNDQGMFTIDSSTGSI 158 Query: 210 SLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + + D E YRL + AQD + T ++I+++D NDNAP F + + ++ E Sbjct: 159 TTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRE 218 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N P + V A D D G NA +TY++ ++G + ++ ++G + T LD ET Sbjct: 219 NTPAA-QVAIVTATDRDSGTNAAITYSL----FSG--ENKFMMNSKTGEIRTVTPLDHET 271 Query: 329 QAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 + Y + ++A DG G + E P T +VT Sbjct: 272 KDSYTMRISAFDGKHTTFVPLVINILDVNEPPRFQDDCTRRGDCSATVLESAPLNTRIVT 331 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 L ATD D D+ L Y + +++ + +GR +T+ + LD + + Y L V A+D G Sbjct: 332 LAATDPDGDSLL-YSVRIRDSQEKIFTIDNSGR--LTLNKMLDREAKSAYDLVVEASD-G 387 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 A ++I + D N+ AP F + Y V+ED +G+ V ++A D DVGINA+++YS Sbjct: 388 NIIAIAALKITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYS 447 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 L V+ F ++ Q G I T DRET + Y + + A+DGG PS S V Sbjct: 448 L--------VSGDTSYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATV 498 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 EI ++DVNDN PVF YTA++ ED +G ++ V A+D D G N + Y + Sbjct: 499 EIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNH 558 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 +F +D +GV+ +++LD E +++ L D G+PP + T + I + DIND+PPVF Sbjct: 559 -AFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVF 617 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + EN+P GT ++ A D D N + + I G+D F+++ G Sbjct: 618 SPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGI---- 670 Query: 748 LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPV 793 + DYE+ + +Y+L ++A P ++ +V I + DVND++PV Sbjct: 671 ISIAKSPDYEN-KTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPV 718 Score = 302 bits (741), Expect = 3e-81 Identities = 261/846 (30%), Positives = 399/846 (47%), Gaps = 107/846 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+SP F +Y +V E ++G+ +L + A+D D G N V Y+I ++ + Sbjct: 1410 LTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSI--ISGNHG 1467 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N FRID +G + +DRE +A Y + + A D P Sbjct: 1468 N-----------------AFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPP---W 1507 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 STA + + + D+NDN P F+ + +DE +S+ +A + ATD D Sbjct: 1508 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSR--VAVVTATDRDE--------- 1556 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 G N Q+ +SI + GD S I A +G +L +++ Sbjct: 1557 --GSNAQVFYSI--VRGDTSA-------------FAINAMNG----------VLTVKKEI 1589 Query: 251 N-DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N + P T + SV EN S++ V A D+D G NA L Y++ +GN + Sbjct: 1590 NRETVP---TQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSII----SGNDEKRF 1642 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ SG + T+ LD E +++Y L VTATD +A F Sbjct: 1643 KINSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQ 1699 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y + E+ P T VV ++A+D D Y I GG +FSI ++G +I+ A L Sbjct: 1700 NYTASVRENSPTSTSVVKVSASDRDS-----YSIVGGKDSDKFSIDQRSG--IISTADVL 1752 Query: 430 DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + Y + V TD+G S+ V I I D N+ +P F+++ Y++S+ E++ + Sbjct: 1753 DRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSF 1812 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 ++ATD+D G NA+ITY+LS N+A F+I +G IT + LDRE +S Y Sbjct: 1813 SFKLAATDADEGTNARITYNLSR---NDA-------FMIGASSGVITNVRKLDREQVSIY 1862 Query: 548 LLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 L V A D G P L S+ V I V D NDN P F N+ E+A+VG ++++ A Sbjct: 1863 TLYVQAVDQGNPRLASEWVPVHIRVQDENDNAPRFVSS-GNCNVSENAVVGAIIAELLAV 1921 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D+G G + Y + + E F ID +GVI + LDRE+ +T+DL A D GTPP Sbjct: 1922 DPDLGTGGVVSYRILTRQTE---FTIDNTTGVITLAQPLDRENKSTYDLAIQARDHGTPP 1978 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 Q+S++ + + + DIND P+ S L + EN P T + I A D D G NA + +S+ Sbjct: 1979 QASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSL 2038 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEIL 783 + + F+L+ G ++ T V LD E + Y L I A +P L + V I Sbjct: 2039 LSNEHKSVFTLDNTTG----DISTKVPLDREQ-QAVYTLRIGVADKGNPSLSSVADVIID 2093 Query: 784 VTDVNDNAPVMKDFQIIFN-NYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLIL 841 V D +DN P + + +N + P G +V A D D Y I S + Sbjct: 2094 VIDEDDNCPRFQPTE--YNVTISESLPRGASIVQVTARDIDGDKDTSYAIKSMTPSGGFT 2151 Query: 842 LNETTG 847 ++ TG Sbjct: 2152 IDSKTG 2157 Score = 284 bits (697), Expect = 6e-76 Identities = 225/708 (31%), Positives = 329/708 (46%), Gaps = 57/708 (8%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S+ IH ++VLD ND++P FE + +RE AS +TVL +K D+D G N + Sbjct: 1094 SITASIH--VSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITL- 1150 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 +L+ E + D F ID +G +L++ LD E A Y + V A D Sbjct: 1151 -------SLSGEGS------------DNFTIDS-TGFVLSKTPLDYETTAAYQLTVTARD 1190 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 SP S+TA + + II+ NDN P F S+ ED+++ N + K+ ATD+D Sbjct: 1191 GGSPSK---SATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAI--NTHVVKLNATDSD- 1244 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 + + + I+ GN F ID SG +S+ K LD E +Y LV+RA + GS S Sbjct: 1245 --GTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYN 1302 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I + DVNDNAP F + +S+ EN+PIG ++ +V A D DEG NA++TY ++ D Sbjct: 1303 NATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDT 1362 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + ++P +G V T LDRE QA Y L VTA D G P +SA A Sbjct: 1363 S-----KFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLND 1417 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F +Y + + E+ G+ ++ + A+D D + R+ Y I GN F I S G Sbjct: 1418 NSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTG 1477 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTAS 477 R ITV +D + Y LT+SA DSG TA V I + D N+ +P+F + + Sbjct: 1478 R--ITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYG 1535 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E IG+ V VV+ATD D G NAQ+ YS+ V F IN G +T K Sbjct: 1536 IDEGVSIGSRVAVVTATDRDEGSNAQVFYSI--------VRGDTSAFAINAMNGVLTVKK 1587 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 ++RET+ + R+ S S T V DV N V + + + N E Sbjct: 1588 EINRETVPTQSYIGSVRENSAQSTSVLT-VAADDSDVGAN-AVLRYSIISGN-DEKRFKI 1644 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 S S V T + + Y L+ + S + IR D T Sbjct: 1645 NSTSGVIMTTTPLDFEEKSQYGLEVTATD--SKYTAKTNVTIRVINLNDITPAFTQQNYT 1702 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 ++ +P +ST +V + D + V D F I + S I +T Sbjct: 1703 ASVRENSP--TSTSVVKVSASDRDSYSIVGGKDSDKFSIDQRSGIIST 1748 Score = 283 bits (695), Expect = 1e-75 Identities = 226/728 (31%), Positives = 344/728 (47%), Gaps = 86/728 (11%) Query: 26 QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXX 85 Q Y SVRE ++ T+VLT+ A D D+G NA + Y+I ++ D Sbjct: 1597 QSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI-------ISGND----------- 1638 Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + F+I+ SG ++T LD E+ ++Y + V ATD + ++ + + +I+ ND Sbjct: 1639 -EKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS------KYTAKTNVTIRVINLND 1691 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 P F+++ YT SV E+ S T V+ K+ A+D D Y+I+GG +FSID Sbjct: 1692 ITPAFTQQNYTASVREN-SPTSTSVV-KVSASDRD-------SYSIVGGKDSDKFSIDQR 1742 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 SG +S LD E V Y + +R D G+P SN T + I I D NDN+P+F +S + S Sbjct: 1743 SGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSS 1802 Query: 266 VSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + EN P +S ++ A DADEG NA +TY ++ D I SG + +L Sbjct: 1803 ILENSAPSSFSF-KLAATDADEGTNARITYNLSRND-------AFMIGASSGVITNVRKL 1854 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE + Y L V A D G+P ++ ++E+ G Sbjct: 1855 DREQVSIYTLYVQAVDQGNPRLASEWVPVHIRVQDENDNAPRFVSSGNCNVSENAVVGAI 1914 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + L A D D + Y I T T N G+IT+AQPLD + + Y L + Sbjct: 1915 IAELLAVDPDLGTGGVVSYRILTRQT----EFTIDNTTGVITLAQPLDRENKSTYDLAIQ 1970 Query: 443 ATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D G + + I +T D N++ P+ ++ SV E+ P T V+ + A+D+D G+ Sbjct: 1971 ARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGL 2030 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NA++T+SL +SNE H F ++ TG I+T LDRE + Y L + D G PS Sbjct: 2031 NAELTFSL---LSNE----HKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPS 2083 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 LS DV I V+D +DN P F+ Y I E G S+ QV A D D + Y + Sbjct: 2084 LSSVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDIDGDKD--TSYAI 2141 Query: 621 DPKDREEGSFVIDPASGVIR-TNKALDRESV---------------ATHDL------KAV 658 G F ID +GV+ + +DRE AT+D + + Sbjct: 2142 KSM-TPSGGFTIDSKTGVVMVASSGVDREIADVFKLVIRAGKEHCGATNDTGGGEGGRFL 2200 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 + T P S + I++ D+ND+ P F D + ++ + + + +RA D D G Sbjct: 2201 GVQQATYPDSLATVT-IQVTDVNDNAPSFSRDSYEYDFNDVTTV--NLLSVRATDLDAGV 2257 Query: 719 NAVVHYSI 726 N VV + + Sbjct: 2258 NGVVKFRL 2265 Score = 260 bits (638), Expect = 9e-69 Identities = 221/750 (29%), Positives = 344/750 (45%), Gaps = 72/750 (9%) Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV 212 ++Y SV E+ + + + + + A D+DVGAN+ +RY+II GN + +F I+S SG + Sbjct: 1597 QSYIGSVRENSAQSTS--VLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTT 1654 Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 LD+E+ Y L + A D +++N T +IN+ ND P F + SV EN P Sbjct: 1655 TPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINL---NDITPAFTQQNYTASVRENSPT 1711 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 S+V+V A D D +Y++ G +ID RSG + T+ LDRE + Y Sbjct: 1712 STSVVKVSASDRD-------SYSIVG----GKDSDKFSIDQRSGIISTADVLDRELVSLY 1760 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 + V TD G+PP S F Y + E+ P + L ATD Sbjct: 1761 AIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATD 1820 Query: 393 ADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-- 448 ADE + R+ Y ++ + F I + + G+IT + LD +Q Y L V A D G Sbjct: 1821 ADEGTNARITYNLSRNDA---FMIGASS--GVITNVRKLDREQVSIYTLYVQAVDQGNPR 1875 Query: 449 -RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 S+ V I + D N+ AP F ++ +V E+A +G + + A D D+G ++Y Sbjct: 1876 LASEWVPVHIRVQDENDNAPRFVSSG-NCNVSENAVVGAIIAELLAVDPDLGTGGVVSYR 1934 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 + + +F I+ TG IT + LDRE S Y L + ARD G P + + + Sbjct: 1935 ILT---------RQTEFTIDNTTGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITI 1985 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ++V+D+ND+ P+ ++ E+ T V ++ A+DAD GLN + + L + + Sbjct: 1986 RVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSL-LSNEHK 2044 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 F +D +G I T LDRE A + L+ D G P SS V I + D +D+ P F Sbjct: 2045 SVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRF 2104 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + ISE+ P G +I ++ A D D + Y+IK S F+++++ G Sbjct: 2105 QPTEYNVTISESLPRGASIVQVTARDIDGDKD--TSYAIKSMTPSGGFTIDSKTG---VV 2159 Query: 748 LVTMVDLDYESPRKKYELVIRAASP--PLWND---------------------VRVEILV 784 +V +D E ++LVIRA ND V I V Sbjct: 2160 MVASSGVDREI-ADVFKLVIRAGKEHCGATNDTGGGEGGRFLGVQQATYPDSLATVTIQV 2218 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILS----GNNANL 839 TDVNDNAP + ++ D V R DA V +++R+ G N + Sbjct: 2219 TDVNDNAPSFSRDSYEY-DFNDVTTVNLLSVRATDLDAGVNGVVKFRLAEQTELGGNRVV 2277 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 + GS +LS Q++ V + E V Sbjct: 2278 KVEAYDQGSPSLSSQVSVIVQTSVSCEAMV 2307 Score = 243 bits (595), Expect = 1e-63 Identities = 186/607 (30%), Positives = 292/607 (48%), Gaps = 49/607 (8%) Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F + SV E + +++ V + V+ L Y++ D GN TID +G Sbjct: 106 FAKDSYSASVKEELQATQNVITVSS-----SVSPNLRYSIMD----GNDQGMFTIDSSTG 156 Query: 317 WVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 + T+G+ DRE++++Y+L V A D + F Y + Sbjct: 157 SITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNI 216 Query: 376 AEDEPPG-TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 E+ P +VT T D+ + + Y + G + F + S+ G I PLD + + Sbjct: 217 RENTPAAQVAIVTATDRDSGTNAAITYSLFSGENK--FMMNSKTGE--IRTVTPLDHETK 272 Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN-----APYTASVFEDAPIGTTVL 489 Y + +SA D G + + INI D N P F++ +A+V E AP+ T ++ Sbjct: 273 DSYTMRISAFD-GKHTTFVPLVINILDVNE-PPRFQDDCTRRGDCSATVLESAPLNTRIV 330 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 ++ATD D + YS+ S E + F I+ +G +T NK+LDRE S Y L Sbjct: 331 TLAATDPD---GDSLLYSVRIRDSQEKI------FTID-NSGRLTLNKMLDREAKSAYDL 380 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 V A DG + +++ ++I+V DVNDN P F +Y + ED VG+ V Q+ A D D Sbjct: 381 VVEASDGNIIAIAA---LKITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLD 437 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 VG+N R+ Y L D F +D + GVIRT A DRE+ A++ + A DGG+P +S Sbjct: 438 VGINARLSYSLVSGDTSY--FTVD-SQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSG 494 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 V I+I D+ND+ PVF S T + E+ IG + + A D D G NA + YS G Sbjct: 495 QATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSG 554 Query: 730 DDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYEL---VIRAASPPLWNDVRVEILVT 785 + +++F+L+ G +VT+ LD+E R Y L V SPPL + + I V Sbjct: 555 NTNHAFTLDAVTG-----VVTVSRSLDFEQ-RSSYALGLSVTDRGSPPLTDTSHLLINVN 608 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845 D+NDN PV + K+ P G D+ L + I+ GN+ + ++ + Sbjct: 609 DINDNPPVFSP-SAYQSRVKENTPAGTQVSATDRDSSTNGALVFGIIKGNDDGVFTIDGS 667 Query: 846 TGSMTLS 852 TG ++++ Sbjct: 668 TGIISIA 674 Score = 109 bits (262), Expect = 3e-23 Identities = 89/315 (28%), Positives = 150/315 (47%), Gaps = 49/315 (15%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V+D NDH P+ SVRE T V+ + A+D D G NAE+ +++ Sbjct: 1986 RVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSL------- 2038 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ E + VF +D +G + T+ LDRE+ A YT+ + D+ +P Sbjct: 2039 LSNEH------------KSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNP---S 2083 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS A + +++ID++DN P+F Y V++ E S+ I ++ A D D +++ Y Sbjct: 2084 LSSVADVIIDVIDEDDNCPRFQPTEYNVTISE--SLPRGASIVQVTARDIDGDKDTS--Y 2139 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRA----------QDGGSPSR- 237 AI F+IDS +G V + + +D E ++LVIRA GG R Sbjct: 2140 AIKSMTPSGGFTIDSKTGVVMVASSGVDREIADVFKLVIRAGKEHCGATNDTGGGEGGRF 2199 Query: 238 ---------SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 + + I + DVNDNAP F ++ ++ + +++ V+A D D GV Sbjct: 2200 LGVQQATYPDSLATVTIQVTDVNDNAPSFSRDSYEYDFNDVTTV--NLLSVRATDLDAGV 2257 Query: 289 NAELTYTMTDKDYTG 303 N + + + ++ G Sbjct: 2258 NGVVKFRLAEQTELG 2272 Score = 55.2 bits (127), Expect = 7e-07 Identities = 52/219 (23%), Positives = 100/219 (45%), Gaps = 31/219 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD-- 68 I+V+D +D+ P F+ +Y ++ E G +++ + T +DI + + Y I+ +T Sbjct: 2092 IDVIDEDDNCPRFQPTEYNVTISESLPRGASIV--QVTARDIDGDKDTSYAIKSMTPSGG 2149 Query: 69 -TLNPEDAXXXXXXXXXX--VQDVFRIDGRSGALLTRASLDRE--KVARYTVLVKATDQA 123 T++ + + DVF++ R+G A+ D + R+ + +AT Sbjct: 2150 FTIDSKTGVVMVASSGVDREIADVFKLVIRAGKEHCGATNDTGGGEGGRFLGVQQATYP- 2208 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 S AT+ + + D NDN P FS +Y ++ +V + ++ATD D G Sbjct: 2209 -------DSLATVTIQVTDVNDNAPSFSRDSYEYDFNDVTTVN----LLSVRATDLDAGV 2257 Query: 184 NSAIRYAI-----IGGNTQMQFSI-----DSLSGDVSLV 212 N +++ + +GGN ++ SLS VS++ Sbjct: 2258 NGVVKFRLAEQTELGGNRVVKVEAYDQGSPSLSSQVSVI 2296 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/44 (38%), Positives = 21/44 (47%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 C + C PC+N C D TY C C+ G TGK C + G Sbjct: 2584 CQFNLNECKGDPCFNNGTCQDRNGTYQCTCRPGSTGKQCELTEG 2627 Score = 33.1 bits (72), Expect = 3.3 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 8/84 (9%) Query: 816 VPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873 V A D+DV L+Y I+SGN+ +N T+G + + L+ +EV+ TD Sbjct: 1616 VAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATD-- 1673 Query: 874 NEIKAMMQLSVRLITEEMLLNSIT 897 ++ A +++R+I LN IT Sbjct: 1674 SKYTAKTNVTIRVIN----LNDIT 1693 >SB_58036| Best HMM Match : Cadherin (HMM E-Value=0) Length = 6074 Score = 386 bits (949), Expect = e-106 Identities = 273/908 (30%), Positives = 438/908 (48%), Gaps = 75/908 (8%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++ VLDCND+ PVF Y + E S GT +L + A D+D+G NA++ Y I Sbjct: 2660 HVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDVGTNAKLSYAI----- 2714 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 V + F ID +G L T L+RE + + + V ATDQ P Sbjct: 2715 --------------TKGNVNETFAIDHTTGELHTTKLLNREDIPGFNLTVTATDQGVP-- 2758 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L +++ + V I+D NDN P+F+ Y V + ED I ++ A+D D N + Sbjct: 2759 -SLHTSSEVLVTILDSNDNIPRFTSPEYHVILPED--TPTGAFILQVTASDQDEDNNRML 2815 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 RY I FS+ + SG+++L LDYE +R +R + +D G+P TT ++I + Sbjct: 2816 RYFINDNQVMKFFSVKASSGNITLKSALDYESIRVFRFQVFVEDNGTPPHLGTTLVVIKV 2875 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN P F T + VSE +G I ++A D+D NA+L + +T+ GNV Sbjct: 2876 TDVNDNDPVFSTLHYTAQVSEASNVGALIAVLKASDSDSTSNAQLNFGITE----GNVKN 2931 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXX 365 ++ G +Y + LD E + Y L V+ D G P R A A Sbjct: 2932 TFYVN-TEGVIYLNRSLDFEERKVYNLSVSVEDSGTPKRKAVIEANVTIYVTDENDCSPV 2990 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F Y + E+ G+ ++ A D D Y I + G F++ G++ Sbjct: 2991 FSQTYYTTAIPENITVGSVILRTVALDLDS---AVYSILNTTSNGTFTVDPHT--GVLRT 3045 Query: 426 AQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 +Q LD + Y LT++ DSG + A V I + D N+ PVF+ Y+ SV E+ Sbjct: 3046 SQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVYSVSVPEN 3105 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +G +L+++A D D G+NA+I Y L I++ ++F +N TG IT + +D Sbjct: 3106 ITVGAHILLLNAKDKDEGVNAEIRYFLKDVIAS-------KRFSMNDTTGQITIKQAVDY 3158 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E S Y V A DGG L+ ++ V I+++DVNDN P F Y ++E+ +GT+V+ Sbjct: 3159 EERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVT 3218 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 Q+ A+D D LNG + + + + +G F+ID +GV+ TNK+LD E V + L A D Sbjct: 3219 QMTASDLDSSLNGNVLFSI-LEGNSDGKFLIDQNTGVVTTNKSLDYEDVTKYTLVIQATD 3277 Query: 662 GGTPPQSSTV--IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GP 718 G PP +S+ ++H+ + +IND+ PVF + I EN+ +G I ++A D D Sbjct: 3278 CGDPPLNSSQPGMLHVSVVNINDNSPVFLQKMYSASIDENTAVGHVILRVQATDRDHVNS 3337 Query: 719 NAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----- 771 +++V Y + D F++ + G EL+ + LDYES K Y+ + A Sbjct: 3338 SSIVIYYLDQSDTEAMRYFTINNQTG----ELILVSSLDYES-TKGYQFTVFAGDNIAQF 3392 Query: 772 ---PPLWNDVRV-----EILVTDVNDNAP-VMKDFQ--IIFNNYKDCFPVGPFGRVPAYD 820 + + RV +I + D+NDN P ++ + I ++ + A D Sbjct: 3393 RKRRDIGDQARVAAVLIDISILDINDNRPKFLRPYNKIEITEGTREGTMILTLQATDA-D 3451 Query: 821 ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880 + + KL Y IL+ + ++ TG + S +L+ T+ ++V D + + Sbjct: 3452 SGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAA 3511 Query: 881 QLSVRLIT 888 Q ++ IT Sbjct: 3512 QPAIVSIT 3519 Score = 385 bits (948), Expect = e-106 Identities = 276/923 (29%), Positives = 442/923 (47%), Gaps = 72/923 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++LD ND+ P F + + EG T +LTL+ATD D G NA++ Y+I T++ Sbjct: 3848 ISILDINDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGVNAKLVYSILNTTSN-- 3905 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F +D +G L T LDRE V YT+ + D P+ + Sbjct: 3906 -----------------GTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLND- 3947 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + AT+ + ++D+NDN P F ++ Y+VS+ E+I+V + I + A D D G N+ IRY Sbjct: 3948 AQPATVSITVLDENDNVPVFDQEVYSVSIPENITVGAH--ILLLNARDKDEGVNAEIRYF 4005 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + +FS++ +G +++ + +DYE+ SY + A DGG + ++ + I I DV Sbjct: 4006 LKDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDV 4065 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + + ENV IG ++ +V A D D +N ++ +++ + GN D Sbjct: 4066 NDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILE----GNSDGKFV 4121 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMP 368 ID +G V T+ LD E +Y L++ ATD GDPP S F Sbjct: 4122 IDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ 4181 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ G ++ + ATD D NR + Y + +T T N G + + Sbjct: 4182 KIYSASIDENTTVGHVILRVQATDRDHVNRSSIVIYSLDQSDTEAMRYFTINNRTGELIL 4241 Query: 426 AQPLDFKQERRYVLTVSATDS----------GGRSDTA--MVQINITDANNYAPVFENAP 473 LD++ +RY TV A D+ G ++ A ++ I+I D N+ P F + Sbjct: 4242 VSSLDYESTKRYEFTVFAGDNTAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSY 4301 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + E T +L + ATD+D G+NA++ YS+ + SN F ++P TG + Sbjct: 4302 NKIEITEGTRESTMILTLQATDADSGMNAKLVYSILNTTSNGT-------FTVDPHTGVL 4354 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 T++ LDRET++ Y LT+T D G P L + V I+V+D NDN PVF Q++Y+ +I Sbjct: 4355 RTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVYSVSIP 4414 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESV 650 E+ VG + + A D D G+N I Y L KD F ++ +G I +A+D E Sbjct: 4415 ENITVGAHILLLNAKDKDEGVNAEIRYFL--KDLIASKRFSMNDTTGQITIKQAVDYEER 4472 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 +++ + A DGG + + V I I D+ND+ P F + EN IGTT+ ++ Sbjct: 4473 SSYSFEVFASDGGETRLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVT 4532 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA- 769 A D D N V +SI G+ F ++ G + T LDYE KY LVI+A Sbjct: 4533 ASDLDSSLNGKVLFSILEGNSDGKFVIDQNTG----VVTTNKSLDYEDV-TKYTLVIQAT 4587 Query: 770 --ASPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT 824 PPL + + + V ++NDN+PV +I + + VG RV A D D Sbjct: 4588 DCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ-KIYSASIDENTTVGHVILRVQATDRDHV 4646 Query: 825 DKLQYRILSGNNAN-----LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879 ++ I S + ++ +N TG + L L+ K V D + + + Sbjct: 4647 NRSSIVIYSLDQSDTEAMRYFAINNQTGELILVSSLDYESTKRYEFTVFAGDNIAQFRKR 4706 Query: 880 MQLSVRLITEEMLLNSITVRLND 902 + + +L++ + +ND Sbjct: 4707 RDIRDQARVAAVLIDISILDIND 4729 Score = 383 bits (942), Expect = e-105 Identities = 276/899 (30%), Positives = 441/899 (49%), Gaps = 78/899 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+ PVF+ + Y SV E + G +L L A D+D G NAE+ Y ++ V A Sbjct: 3081 ITVLDENDNVPVFDQEVYSVSVPENITVGAHILLLNAKDKDEGVNAEIRYFLKDVIASKR 3140 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ++ +G + + ++D E+ + Y+ V A+D RL Sbjct: 3141 -------------------FSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEA---RL 3178 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + ++++ + IID NDN P F Y V + E++++ + ++ A+D D N + ++ Sbjct: 3179 TGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI--GTTVTQMTASDLDSSLNGNVLFS 3236 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIR 248 I+ GN+ +F ID +G V+ K+LDYE V Y LVI+A D G P + S L +++ Sbjct: 3237 ILEGNSDGKFLIDQNTGVVTTNKSLDYEDVTKYTLVIQATDCGDPPLNSSQPGMLHVSVV 3296 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 ++NDN+P F ++ S+ EN +G+ I+RVQA D D ++ + D+ T + Sbjct: 3297 NINDNSPVFLQKMYSASIDENTAVGHVILRVQATDRDHVNSSSIVIYYLDQSDTEAMRY- 3355 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG----------GDPPRSATATXXXXXXX 358 TI+ ++G + LD E+ YQ V A D GD R A Sbjct: 3356 FTINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAVLIDISILD 3415 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 F+ ++E+ E GT ++TL ATDAD + +L Y I + G F++ Sbjct: 3416 INDNRPKFLRPYNKIEITEGTREGTMILTLQATDADSGMNAKLVYSILNTTSNGTFTVDP 3475 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENA 472 G++ +Q LD + Y LT++ DSG + A+V I + D N+ PVF+ Sbjct: 3476 HT--GVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPAIVSITVLDENDNIPVFDQE 3533 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y+ SV E+ +G +L+++A D D G+NA+I Y L I + ++F IN TG Sbjct: 3534 VYSVSVPENITVGGHILLLNARDKDEGVNAEIRYFLKDAIVS-------KKFSINDTTGQ 3586 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 IT + +D E S Y V A DGG L+ ++ V I+++DVNDN P F Y ++E Sbjct: 3587 ITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVE 3646 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 + +GT V+QV A+D D LNG++ + + +G FVID +GV+ TNK+LD E V Sbjct: 3647 NVAIGTPVTQVTASDLDSSLNGKVLFSI-LGGNSDGKFVIDQNTGVVTTNKSLDYEDVTE 3705 Query: 653 HDLKAVAIDGGTPPQSSTV--IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + L A D G PP +S+ ++H+ + +IND+ PVF + I EN+ +G I ++ Sbjct: 3706 YTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVQ 3765 Query: 711 AHDPDE-GPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 A D D +++V YS+ D F++ R G EL+ + LDYES K Y+ + Sbjct: 3766 ATDRDHVNSSSIVIYSLDQSDTEAMRYFTINNRTG----ELILVSSLDYES-TKGYQFTV 3820 Query: 768 RAAS--------PPLWNDVRV-----EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814 A + + RV +I + D+NDN P + Sbjct: 3821 FAGDNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSYNKIEITEGTRESTMIL 3880 Query: 815 RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + A DAD V KL Y IL+ + ++ TG + S +L+ T+ ++V D Sbjct: 3881 TLQATDADSGVNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHD 3939 Score = 382 bits (941), Expect = e-105 Identities = 276/923 (29%), Positives = 438/923 (47%), Gaps = 72/923 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++LD ND+ P F + + EG GT +LTL+ATD D G NA++ Y+I T++ Sbjct: 3411 ISILDINDNRPKFLRPYNKIEITEGTREGTMILTLQATDADSGMNAKLVYSILNTTSN-- 3468 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F +D +G L T LDRE V YT+ + D P+ + Sbjct: 3469 -----------------GTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNA- 3510 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + A + + ++D+NDN P F ++ Y+VSV E+I+V + I + A D D G N+ IRY Sbjct: 3511 AQPAIVSITVLDENDNIPVFDQEVYSVSVPENITVGGH--ILLLNARDKDEGVNAEIRYF 3568 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + +FSI+ +G +++ + +DYE+ SY + A DGG + ++ + I I DV Sbjct: 3569 LKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDV 3628 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + + ENV IG + +V A D D +N ++ +++ GN D Sbjct: 3629 NDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSILG----GNSDGKFV 3684 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMP 368 ID +G V T+ LD E +Y L++ ATD GDPP S F Sbjct: 3685 IDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ 3744 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ G ++ + ATD D N + Y + +T T N G + + Sbjct: 3745 KMYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRYFTINNRTGELIL 3804 Query: 426 AQPLDFKQERRYVLTVSATDS----------GGRSDTA--MVQINITDANNYAPVFENAP 473 LD++ + Y TV A D+ G ++ A ++ I+I D N+ P F + Sbjct: 3805 VSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSY 3864 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + E T +L + ATD+D G+NA++ YS+ + SN F ++P TG + Sbjct: 3865 NKIEITEGTRESTMILTLQATDADSGVNAKLVYSILNTTSNGT-------FTVDPHTGVL 3917 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVFKQQLYTANIM 591 T++ LDRET++ Y LT+T D G P L+D V I+V+D NDN PVF Q++Y+ +I Sbjct: 3918 RTSQRLDRETVTEYTLTITVHDSGDPMLNDAQPATVSITVLDENDNVPVFDQEVYSVSIP 3977 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESV 650 E+ VG + + A D D G+N I Y L KD F ++ +G I +A+D E Sbjct: 3978 ENITVGAHILLLNARDKDEGVNAEIRYFL--KDAIVSKRFSMNDTTGQITIKQAVDYEER 4035 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 +++ + A DGG + + V I I D+ND+ P F + EN IGTT+ ++ Sbjct: 4036 SSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVT 4095 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA- 769 A D D N V +SI G+ F ++ G + T LDYE +Y LVI+A Sbjct: 4096 ASDLDSSLNGKVLFSILEGNSDGKFVIDQNTG----VVTTNKSLDYEDV-TEYTLVIQAT 4150 Query: 770 --ASPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT 824 PPL + + + V ++NDN+PV +I + + VG RV A D D Sbjct: 4151 DCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ-KIYSASIDENTTVGHVILRVQATDRDHV 4209 Query: 825 DKLQYRILSGNNAN-----LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879 ++ I S + ++ +N TG + L L+ K V D + + Sbjct: 4210 NRSSIVIYSLDQSDTEAMRYFTINNRTGELILVSSLDYESTKRYEFTVFAGDNTAQFRKR 4269 Query: 880 MQLSVRLITEEMLLNSITVRLND 902 + + +L++ + +ND Sbjct: 4270 RDIGDQARVAAVLIDISILDIND 4292 Score = 379 bits (932), Expect = e-104 Identities = 280/920 (30%), Positives = 439/920 (47%), Gaps = 70/920 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+ P+F +Y + E +SGT VLTL A D+D G N +V Y I VT+ Sbjct: 2558 VKVLDANDNPPIFNQSEYYVEMYENVTSGTQVLTLFAHDRDEGINGQVFYYI--VTSS-- 2613 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V+ VF + +G + A LDRE V +Y +LV A D SP Sbjct: 2614 ---------------VKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPR--- 2655 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +++A + V ++D NDN P F+ YT+ + E S+ I ++ A D DVG N+ + YA Sbjct: 2656 TASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTR--ILRVSANDRDVGTNAKLSYA 2713 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN F+ID +G++ K L+ E + + L + A D G PS ++++L+ I D Sbjct: 2714 ITKGNVNETFAIDHTTGELHTTKLLNREDIPGFNLTVTATDQGVPSLHTSSEVLVTILDS 2773 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN PRF + + + E+ P G I++V A D DE N L Y + D V + Sbjct: 2774 NDNIPRFTSPEYHVILPEDTPTGAFILQVTASDQDEDNNRMLRYFIND----NQVMKFFS 2829 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 + SG + LD E+ ++ V D G PP T F Sbjct: 2830 VKASSGNITLKSALDYESIRVFRFQVFVEDNGTPPHLGTTLVVIKVTDVNDNDPVFSTLH 2889 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y +++E G + L A+D+D + +L++ IT GN + F + N G+I + + Sbjct: 2890 YTAQVSEASNVGALIAVLKASDSDSTSNAQLNFGITEGNVKNTFYV---NTEGVIYLNRS 2946 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQIN----ITDANNYAPVFENAPYTASVFEDAPI 484 LDF++ + Y L+VS DSG A+++ N +TD N+ +PVF YT ++ E+ + Sbjct: 2947 LDFEERKVYNLSVSVEDSGTPKRKAVIEANVTIYVTDENDCSPVFSQTYYTTAIPENITV 3006 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G+ +L A D D + YS+ + SN F ++P TG + T++ LDRET+ Sbjct: 3007 GSVILRTVALDLDSAV-----YSILNTTSNGT-------FTVDPHTGVLRTSQRLDRETV 3054 Query: 545 SGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + Y LT+T D G P L + V I+V+D NDN PVF Q++Y+ ++ E+ VG + Sbjct: 3055 TEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVYSVSVPENITVGAHILL 3114 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + A D D G+N I Y L + F ++ +G I +A+D E +++ + A DG Sbjct: 3115 LNAKDKDEGVNAEIRYFLKDVIASK-RFSMNDTTGQITIKQAVDYEERSSYSFEVFASDG 3173 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G + + V I I D+ND+ P F + EN IGTT+ ++ A D D N V Sbjct: 3174 GEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQMTASDLDSSLNGNV 3233 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV- 778 +SI G+ F ++ G + T LDYE KY LVI+A PPL + Sbjct: 3234 LFSILEGNSDGKFLIDQNTG----VVTTNKSLDYEDV-TKYTLVIQATDCGDPPLNSSQP 3288 Query: 779 -RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK----LQYRIL 832 + + V ++NDN+PV ++ + + VG RV A D D + + Y Sbjct: 3289 GMLHVSVVNINDNSPVFLQ-KMYSASIDENTAVGHVILRVQATDRDHVNSSSIVIYYLDQ 3347 Query: 833 SGNNA-NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 S A +N TG + L L+ K V D + + + + + + Sbjct: 3348 SDTEAMRYFTINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAV 3407 Query: 892 LLNSITVRLNDMTAEQFLSP 911 L++ + +ND +FL P Sbjct: 3408 LIDISILDIND-NRPKFLRP 3426 Score = 372 bits (916), Expect = e-102 Identities = 269/904 (29%), Positives = 438/904 (48%), Gaps = 72/904 (7%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60 S P +H ++V++ ND+SPVF + Y AS+ E + G +L ++ATD+D + +++ V Y Sbjct: 4597 SQPGMLH--VSVVNINDNSPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNRSSIVIY 4654 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 +++ + + F I+ ++G L+ +SLD E RY V A Sbjct: 4655 SLDQSDTEAMR-----------------YFAINNQTGELILVSSLDYESTKRYEFTVFAG 4697 Query: 121 DQASPVSDRLS-------STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 D + R + I ++I+D NDN P+F + + + E ++ +I Sbjct: 4698 DNIAQFRKRRDIRDQARVAAVLIDISILDINDNRPKFLQSYNKIEITE--GTRESTMILT 4755 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 ++ATDAD G N+ + Y+I+ + F++D +G + + LD E V Y L I D G Sbjct: 4756 LQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 4815 Query: 234 SPSRSNTTQLLINIR--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 P + +++I D NDN P F ++ S+ EN+ +G I+ + A D DEGVNAE Sbjct: 4816 DPMLNAAQPAIVSITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAE 4875 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + Y + D V +++ +G + +D E ++ Y V A+DGG+ + +++ Sbjct: 4876 IRYFLKD----AIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSS 4931 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409 F+P +Y V+L E+ GT V LTA+D D + ++ + I GN+ Sbjct: 4932 VRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQLTASDLDSSLNGKVLFSILEGNSD 4991 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465 G+FSI QN G++T + LD++ Y L + ATD G S M+ +++ + N+ Sbjct: 4992 GKFSI-DQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 5049 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524 +PVF Y+AS+ E+ +G +L V ATD D V ++ + YSL + EA+ + F Sbjct: 5050 SPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSL-DQSDTEAMRY----F 5104 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTA----------RDGGVPSLSDTTDVEISVVDV 574 IN QTG + LD E+ GY TV A RD G + ++IS++D+ Sbjct: 5105 AINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKNRDIGDQARVAAVLIDISILDI 5164 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 NDN P F Q I E T + + ATDAD G+N ++ Y + G+F +DP Sbjct: 5165 NDNRPKFPQPYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI-LNTTSNGTFTVDP 5223 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCL 692 +GV+RT++ LDRE+V + L D G P + T V I + D ND+ PVF+ + Sbjct: 5224 HTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQTATVSITVLDENDNVPVFDQEVY 5283 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + I EN +G I + A D DEG NA + Y +K S FS+ G ++ Sbjct: 5284 SVSIPENITVGAHILLLNARDKDEGVNAEILYFLKDVIASKRFSMNDTTG----QITIKQ 5339 Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 +DYE R Y + A+ L V I + DVNDN P + ++ Sbjct: 5340 AVDYEE-RSSYSFEVFASDSGEARLTGSSSVRIPIIDVNDNRPYFLPTRYYVQLVENVAI 5398 Query: 810 VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 +V A D D + K+ + IL GN+ ++++ TG +T + L+ T+ + Sbjct: 5399 GTTVTQVYASDLDSSLNGKVLFSILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVI 5458 Query: 868 SVTD 871 TD Sbjct: 5459 QATD 5462 Score = 370 bits (911), Expect = e-102 Identities = 270/904 (29%), Positives = 436/904 (48%), Gaps = 72/904 (7%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60 S P +H ++V++ ND+SPVF + Y AS+ E + G +L ++ATD+D + ++ V Y Sbjct: 3286 SQPGMLH--VSVVNINDNSPVFLQKMYSASIDENTAVGHVILRVQATDRDHVNSSSIVIY 3343 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 ++ +DT F I+ ++G L+ +SLD E Y V A Sbjct: 3344 YLD--QSDT---------------EAMRYFTINNQTGELILVSSLDYESTKGYQFTVFAG 3386 Query: 121 DQAS------PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 D + + D+ A I ++I+D NDN P+F + + E + +I Sbjct: 3387 DNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLRPYNKIEITE--GTREGTMILT 3444 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 ++ATDAD G N+ + Y+I+ + F++D +G + + LD E V Y L I D G Sbjct: 3445 LQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 3504 Query: 234 SPSRSNTTQLLINIR--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 P + +++I D NDN P F ++ SV EN+ +G I+ + A D DEGVNAE Sbjct: 3505 DPMLNAAQPAIVSITVLDENDNIPVFDQEVYSVSVPENITVGGHILLLNARDKDEGVNAE 3564 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + Y + D V +I+ +G + +D E ++ Y V A+DGG+ + +++ Sbjct: 3565 IRYFLKD----AIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSS 3620 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409 F+P +Y V+L E+ GTPV +TA+D D + ++ + I GGN+ Sbjct: 3621 VRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSILGGNSD 3680 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465 G+F + QN G++T + LD++ Y L + ATD G S M+ +++ + N+ Sbjct: 3681 GKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 3738 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524 +PVF Y+AS+ E+ +G +L V ATD D V ++ + YSL + EA+ + F Sbjct: 3739 SPVFSQKMYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSL-DQSDTEAMRY----F 3793 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTA----------RDGGVPSLSDTTDVEISVVDV 574 IN +TG + LD E+ GY TV A RD G + ++IS++D+ Sbjct: 3794 TINNRTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAVLIDISILDI 3853 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 NDN P F Q I E T + + ATDAD G+N ++ Y + G+F +DP Sbjct: 3854 NDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGVNAKLVYSI-LNTTSNGTFTVDP 3912 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCL 692 +GV+RT++ LDRE+V + L D G P + V I + D ND+ PVF+ + Sbjct: 3913 HTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNDAQPATVSITVLDENDNVPVFDQEVY 3972 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + I EN +G I + A D DEG NA + Y +K S FS+ G ++ Sbjct: 3973 SVSIPENITVGAHILLLNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTG----QITIKQ 4028 Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 +DYE R Y + A+ L V I + DVNDN P + ++ Sbjct: 4029 AVDYEE-RSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI 4087 Query: 810 VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 +V A D D + K+ + IL GN+ ++++ TG +T + L+ T+ + Sbjct: 4088 GTTVTQVTASDLDSSLNGKVLFSILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVI 4147 Query: 868 SVTD 871 TD Sbjct: 4148 QATD 4151 Score = 366 bits (901), Expect = e-100 Identities = 247/807 (30%), Positives = 394/807 (48%), Gaps = 63/807 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++LD ND+ P F + + EG T +LTL+ATD D G NA++ Y+I T++ Sbjct: 4722 ISILDINDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSILNTTSN-- 4779 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F +D +G L T LDRE V YT+ + D P+ + Sbjct: 4780 -----------------GTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNA- 4821 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + A + + ++D+NDN P F ++ Y+VS+ E+I+V + I + A D D G N+ IRY Sbjct: 4822 AQPAIVSITVLDENDNVPVFDQEVYSVSIPENITVGAH--ILLLNARDKDEGVNAEIRYF 4879 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + +FS++ +G +++ + +DYE+ SY + A DGG + ++ + I I DV Sbjct: 4880 LKDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDV 4939 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + + ENV IG ++ ++ A D D +N ++ +++ + GN D + Sbjct: 4940 NDNRPYFLPTRYYVQLVENVAIGTTVTQLTASDLDSSLNGKVLFSILE----GNSDGKFS 4995 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMP 368 ID +G V T+ LD E +Y L++ ATD GDPP S F Sbjct: 4996 IDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ 5055 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ G ++ + ATD D N + Y + +T N G + + Sbjct: 5056 KIYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRYFAINNQTGELIL 5115 Query: 426 AQPLDFKQERRYVLTVSATDS----------GGRSDTA--MVQINITDANNYAPVFENAP 473 LD++ + Y TV A D+ G ++ A ++ I+I D N+ P F Sbjct: 5116 VSSLDYESTKGYQFTVFAGDNIAQFRKNRDIGDQARVAAVLIDISILDINDNRPKFPQPY 5175 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + E T +L + ATD+D G+NA++ YS+ + SN F ++P TG + Sbjct: 5176 NKIEITEGTRESTMILTLQATDADSGMNAKLVYSILNTTSNGT-------FTVDPHTGVL 5228 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 T++ LDRET++ Y LT+T D G P L + T V I+V+D NDN PVF Q++Y+ +I Sbjct: 5229 RTSQRLDRETVTEYTLTITVHDSGDPMLNAAQTATVSITVLDENDNVPVFDQEVYSVSIP 5288 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 E+ VG + + A D D G+N I Y L + F ++ +G I +A+D E + Sbjct: 5289 ENITVGAHILLLNARDKDEGVNAEILYFLKDVIASK-RFSMNDTTGQITIKQAVDYEERS 5347 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 ++ + A D G + + V I I D+ND+ P F + EN IGTT+ ++ A Sbjct: 5348 SYSFEVFASDSGEARLTGSSSVRIPIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVYA 5407 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769 D D N V +SI G+ F ++ G + T LDYE +Y LVI+A Sbjct: 5408 SDLDSSLNGKVLFSILEGNSDGKFVIDQNTG----VVTTNKSLDYEDV-TEYTLVIQATD 5462 Query: 770 -ASPPLWNDV--RVEILVTDVNDNAPV 793 PPL + + + V ++NDN PV Sbjct: 5463 CGDPPLNSSQPGMLHVSVVNINDNIPV 5489 Score = 363 bits (894), Expect = e-100 Identities = 266/904 (29%), Positives = 437/904 (48%), Gaps = 72/904 (7%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60 S P +H ++V++ ND+SPVF + Y AS+ E + G +L ++ATD+D + ++ V Y Sbjct: 3723 SQPGMLH--VSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVQATDRDHVNSSSIVIY 3780 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 +++ +DT F I+ R+G L+ +SLD E Y V A Sbjct: 3781 SLD--QSDT---------------EAMRYFTINNRTGELILVSSLDYESTKGYQFTVFAG 3823 Query: 121 DQAS------PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 D + + D+ A I ++I+D NDN P+F + + + E ++ +I Sbjct: 3824 DNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSYNKIEITE--GTRESTMILT 3881 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 ++ATDAD G N+ + Y+I+ + F++D +G + + LD E V Y L I D G Sbjct: 3882 LQATDADSGVNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 3941 Query: 234 SP--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 P + + + I + D NDN P F ++ S+ EN+ +G I+ + A D DEGVNAE Sbjct: 3942 DPMLNDAQPATVSITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAE 4001 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + Y + D V +++ +G + +D E ++ Y V A+DGG+ + +++ Sbjct: 4002 IRYFLKD----AIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSS 4057 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409 F+P +Y V+L E+ GT V +TA+D D + ++ + I GN+ Sbjct: 4058 VRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILEGNSD 4117 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465 G+F + QN G++T + LD++ Y L + ATD G S M+ +++ + N+ Sbjct: 4118 GKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 4175 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524 +PVF Y+AS+ E+ +G +L V ATD D V ++ + YSL + EA+ + F Sbjct: 4176 SPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNRSSIVIYSL-DQSDTEAMRY----F 4230 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTA----------RDGGVPSLSDTTDVEISVVDV 574 IN +TG + LD E+ Y TV A RD G + ++IS++D+ Sbjct: 4231 TINNRTGELILVSSLDYESTKRYEFTVFAGDNTAQFRKRRDIGDQARVAAVLIDISILDI 4290 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 NDN P F Q I E T + + ATDAD G+N ++ Y + G+F +DP Sbjct: 4291 NDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI-LNTTSNGTFTVDP 4349 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFESDCL 692 +GV+RT++ LDRE+V + L D G P ++ V I + D ND+ PVF+ + Sbjct: 4350 HTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVY 4409 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + I EN +G I + A D DEG NA + Y +K S FS+ G ++ Sbjct: 4410 SVSIPENITVGAHILLLNAKDKDEGVNAEIRYFLKDLIASKRFSMNDTTG----QITIKQ 4465 Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 +DYE R Y + A+ L V I + DVNDN P + ++ Sbjct: 4466 AVDYEE-RSSYSFEVFASDGGETRLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI 4524 Query: 810 VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 +V A D D + K+ + IL GN+ ++++ TG +T + L+ T+ + Sbjct: 4525 GTTVTQVTASDLDSSLNGKVLFSILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTKYTLVI 4584 Query: 868 SVTD 871 TD Sbjct: 4585 QATD 4588 Score = 359 bits (883), Expect = 2e-98 Identities = 255/800 (31%), Positives = 384/800 (48%), Gaps = 46/800 (5%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST--ATIHVNIIDDN 144 +DV R+ G ++ SLD E A Y + + A D SP RL+S AT+ V ++D N Sbjct: 2509 EDV-RVGSTLGFIIVNDSLDFETTASYNLTIVAFDSGSP---RLASLVPATVFVKVLDAN 2564 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 DN P F++ Y V + E+ VT + + A D D G N + Y I+ + + F+ +S Sbjct: 2565 DNPPIFNQSEYYVEMYEN--VTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNS 2622 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +G VSL LD E V Y +++ AQDGGSP R+ + + + + D NDN P F T + Sbjct: 2623 TTGVVSLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTL 2682 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 +SE IG I+RV A D D G NA+L+Y +T GNV+ ID +G ++T+ L Sbjct: 2683 QLSEATSIGTRILRVSANDRDVGTNAKLSYAIT----KGNVNETFAIDHTTGELHTTKLL 2738 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 +RE + L VTATD G P ++ F +Y V L ED P G Sbjct: 2739 NREDIPGFNLTVTATDQGVPSLHTSSEVLVTILDSNDNIPRFTSPEYHVILPEDTPTGAF 2798 Query: 385 VVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 ++ +TA+D DEDN L Y I FS+ + +G IT+ LD++ R + V Sbjct: 2799 ILQVTASDQDEDNNRMLRYFINDNQVMKFFSVKASSGN--ITLKSALDYESIRVFRFQVF 2856 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 D+G T +V I +TD N+ PVF YTA V E + +G + V+ A+DSD Sbjct: 2857 VEDNGTPPHLGTTLVVIKVTDVNDNDPVFSTLHYTAQVSEASNVGALIAVLKASDSDSTS 2916 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NAQ+ + ++ + F +N + G I N+ LD E Y L+V+ D G P Sbjct: 2917 NAQLNFGITE-------GNVKNTFYVNTE-GVIYLNRSLDFEERKVYNLSVSVEDSGTPK 2968 Query: 561 LSDT--TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 +V I V D ND PVF Q YT I E+ VG+ + + A D D + ++ Sbjct: 2969 RKAVIEANVTIYVTDENDCSPVFSQTYYTTAIPENITVGSVILRTVALDLDSAVYSILN- 3027 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST--VIVHIK 676 G+F +DP +GV+RT++ LDRE+V + L D G P ++ V I Sbjct: 3028 -----TTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSIT 3082 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 + D ND+ PVF+ + + + EN +G I + A D DEG NA + Y +K S FS Sbjct: 3083 VLDENDNVPVFDQEVYSVSVPENITVGAHILLLNAKDKDEGVNAEIRYFLKDVIASKRFS 3142 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPV 793 + G ++ +DYE R Y + A+ L V I + DVNDN P Sbjct: 3143 MNDTTG----QITIKQAVDYEE-RSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPY 3197 Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL 851 + ++ ++ A D D + + + IL GN+ L+++ TG +T Sbjct: 3198 FLPTRYYVQLVENVAIGTTVTQMTASDLDSSLNGNVLFSILEGNSDGKFLIDQNTGVVTT 3257 Query: 852 SPQLNTNVPKLATMEVSVTD 871 + L+ T+ + TD Sbjct: 3258 NKSLDYEDVTKYTLVIQATD 3277 Score = 359 bits (882), Expect = 2e-98 Identities = 281/918 (30%), Positives = 448/918 (48%), Gaps = 83/918 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I ++D ND+ P F +Y + E + GTTV + A+D D N +V ++I +D Sbjct: 4059 RITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILEGNSD- 4117 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID +G + T SLD E V YT++++ATD P + Sbjct: 4118 ------------------GKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNS 4159 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIR 188 S +HV++++ NDN P FS+K Y+ S+DE+ +V VI +++ATD D V +S + Sbjct: 4160 -SQPGMLHVSVVNINDNSPVFSQKIYSASIDENTTV--GHVILRVQATDRDHVNRSSIVI 4216 Query: 189 YAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG----------GSPS 236 Y++ +T+ F+I++ +G++ LV +LDYE + Y + A D G + Sbjct: 4217 YSLDQSDTEAMRYFTINNRTGELILVSSLDYESTKRYEFTVFAGDNTAQFRKRRDIGDQA 4276 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 R + I+I D+NDN P+F S + ++E I+ +QA DAD G+NA+L Y++ Sbjct: 4277 RVAAVLIDISILDINDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI 4336 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXX 354 + G T+DP +G + TS +LDRET +Y L +T D GDP +A AT Sbjct: 4337 LNTTSNGT----FTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSI 4392 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRF 412 F Y V + E+ G ++ L A D DE + + Y + RF Sbjct: 4393 TVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNAKDKDEGVNAEIRYFLKDLIASKRF 4452 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470 S+ G+ IT+ Q +D+++ Y V A+D G + ++ V+I I D N+ P F Sbjct: 4453 SMNDTTGQ--ITIKQAVDYEERSSYSFEVFASDGGETRLTGSSSVRITIIDVNDNRPYFL 4510 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y + E+ IGTTV V+A+D D +N ++ +S+ + D +FVI+ T Sbjct: 4511 PTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILE-------GNSDGKFVIDQNT 4563 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588 G +TTNK LD E ++ Y L + A D G P L+ + + +SVV++NDN PVF Q++Y+A Sbjct: 4564 GVVTTNKSLDYEDVTKYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKIYSA 4623 Query: 589 NIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALD 646 +I E+ VG + +V ATD D V + + Y LD D E F I+ +G + +LD Sbjct: 4624 SIDENTTVGHVILRVQATDRDHVNRSSIVIYSLDQSDTEAMRYFAINNQTGELILVSSLD 4683 Query: 647 RESVATHDLKAVAIDG----------GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 ES ++ A D + + V++ I I DIND+ P F I Sbjct: 4684 YESTKRYEFTVFAGDNIAQFRKRRDIRDQARVAAVLIDISILDINDNRPKFLQSYNKIEI 4743 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 +E + T I ++A D D G NA + YSI + +F+++ G L T LD Sbjct: 4744 TEGTRESTMILTLQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGV----LRTSQRLDR 4799 Query: 757 ESPRKKYELVIRA--ASPPLWNDVR---VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 E+ + Y L I + P+ N + V I V D NDN PV D ++ + + VG Sbjct: 4800 ETVTE-YTLTITVHDSGDPMLNAAQPAIVSITVLDENDNVPVF-DQEVYSVSIPENITVG 4857 Query: 812 P-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 + A D D V +++Y + + +N+TTG +T+ ++ + EV Sbjct: 4858 AHILLLNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVF 4917 Query: 869 VTDGVNEIKAMMQLSVRL 886 +DG E + SVR+ Sbjct: 4918 ASDG-GEARLTGSSSVRI 4934 Score = 354 bits (871), Expect = 5e-97 Identities = 263/863 (30%), Positives = 425/863 (49%), Gaps = 67/863 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +++VLD ND+ P F QY+ +V E G+ ++TL + D D N V + ++++ D Sbjct: 1426 RVDVLDVNDNPPEFLRTQYDVTVSEALLPGSIIVTLVSRDNDSTANGLVRF--DILSGDK 1483 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP--VS 127 FR+ SG+++ SLD E+ YT+L++A D P VS Sbjct: 1484 -----------------NSTFRVT-ESGSIILNKSLDYEQTKEYTLLLRARDVGLPPLVS 1525 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 DR AT+ + ++D ND+ P F Y+ E+ SV + + +++ATD D NS I Sbjct: 1526 DR---NATVLIRVVDLNDHQPVFDLSQYSGVFMENTSVGSS--LLRVRATDQDSNMNSHI 1580 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y + + + F ++ +G+++L++ LD+E Y ++ A D G ++ T + I + Sbjct: 1581 SY-YMNTSQGLPFDVNQTNGEITLIRALDFETRSFYSFIVVASDAGRNRKAVNTLVQIYV 1639 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDNAP F+ ++ ++SE G I +V A D D NA+L + ++ GN + Sbjct: 1640 MDINDNAPVFFPIVYDVTISEATLQGAIIAKVTANDNDSLSNAQLRFAISQ----GNENG 1695 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I+ +G + + +D E Y L +T D G PP + + + Sbjct: 1696 SFAIND-AGILILAHAIDFENTRMYDLTITVHDLGWPPLATSKPARVIIHVYDDNDNSPI 1754 Query: 368 PGQ--YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG-RFSITSQNGRGL 422 GQ YEV L E+ P G + ++ATD D ++ L Y I F IT + G Sbjct: 1755 FGQTVYEVTLKENYPVGQAFLNVSATDRDSRHNSLLSYSIHDAQANAPHFRITDETGE-- 1812 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + ++ LD++ + TV A D G R T +VQ+ + D N+ P+F+ Y ++ E Sbjct: 1813 LRLSSSLDYEARDVFRFTVIARDHGSSPRMGTTLVQVLVQDVNDNRPMFDPYCYNTTISE 1872 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + G V+ VSA D+D NA + Y +S+ + + F I TG I LD Sbjct: 1873 NLLPGMPVVWVSAYDNDSSSNADLKYRISA-------GNKENAFEITA-TGQIRPVIALD 1924 Query: 541 RETMSGYLLTVTARDGGVPSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 E Y LT+ RD G P+L V I V DVNDN P+F Q LY+A I ED VG Sbjct: 1925 HERTGFYNLTIDVRDSGQPALHAMHPATVLIHVFDVNDNAPIFNQTLYSAIIPEDFTVGG 1984 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 ++ V A D D LN R+ Y + E FVID +GV+R++K D E+ + Sbjct: 1985 TLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVR 2044 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A D G+P +S+ +H++I D ND+ P+F+ +SEN+P+GT + ++A D D Sbjct: 2045 AEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTS 2104 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL- 774 NA + YSI+ G+++ SF+++ G E++T + D+E ++Y L I + P L Sbjct: 2105 NADLIYSIQNGNNNGSFTIDNSTG----EIMTRKEFDFEK-TERYNLTISVSDTGVPALS 2159 Query: 775 -WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830 N V I+V D NDN P + Y++ F VG V A D D + + Y Sbjct: 2160 SLNFANVVIIVVDENDNPPEFAQKRYTATVYEN-FTVGDNLFTVKASDKDSHLNGLITYS 2218 Query: 831 ILSGNN-ANLILLNETTGSMTLS 852 I S + A +++E G+++++ Sbjct: 2219 ITSAPSFAGKFVIDEILGNVSIT 2241 Score = 353 bits (868), Expect = 1e-96 Identities = 266/879 (30%), Positives = 413/879 (46%), Gaps = 60/879 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI V+D ND++PVF Y+ ++ E G + + A D D NA++ + I + Sbjct: 1636 QIYVMDINDNAPVFFPIVYDVTISEATLQGAIIAKVTANDNDSLSNAQLRFAI------S 1689 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 E+ F I+ +G L+ ++D E Y + + D P Sbjct: 1690 QGNENGS-------------FAIND-AGILILAHAIDFENTRMYDLTITVHDLGWPPL-A 1734 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S A + +++ DDNDN P F + Y V++ E+ V + ATD D NS + Y Sbjct: 1735 TSKPARVIIHVYDDNDNSPIFGQTVYEVTLKENYPV--GQAFLNVSATDRDSRHNSLLSY 1792 Query: 190 AIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +I F I +G++ L +LDYE +R + A+D GS R TT + + ++ Sbjct: 1793 SIHDAQANAPHFRITDETGELRLSSSLDYEARDVFRFTVIARDHGSSPRMGTTLVQVLVQ 1852 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F + ++SEN+ G +V V AYD D NA+L Y ++ GN + Sbjct: 1853 DVNDNRPMFDPYCYNTTISENLLPGMPVVWVSAYDNDSSSNADLKYRIS----AGNKENA 1908 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXF 366 I +G + LD E Y L + D G P A AT F Sbjct: 1909 FEITA-TGQIRPVIALDHERTGFYNLTIDVRDSGQPALHAMHPATVLIHVFDVNDNAPIF 1967 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y + ED G ++T+ A D D + R+ Y I +T + + N G++ Sbjct: 1968 NQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVID-NITGVVR 2026 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 ++ D++ +R Y +V A D G RS A + + ITD N+ P+F+ Y V E+ Sbjct: 2027 SSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENT 2086 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+GT V V A D D NA + YS+ + +N + F I+ TG I T K D E Sbjct: 2087 PLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGS-------FTIDNSTGEIMTRKEFDFE 2139 Query: 543 TMSGYLLTVTARDGGVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 Y LT++ D GVP+LS +V I VVD NDN P F Q+ YTA + E+ VG ++ Sbjct: 2140 KTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGDNL 2199 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V A+D D LNG I Y + G FVID G + D E ++D A Sbjct: 2200 FTVKASDKDSHLNGLITYSITSAPSFAGKFVIDEILGNVSITSGFDFELEQSYDFVIEAR 2259 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G+PP ++ H+ I D+ND+ PVF + ++E + +GT + + AHD D GPNA Sbjct: 2260 DSGSPPHTAYAHAHVTILDVNDNAPVFPVNNTHLVLTEATEVGTVVLRVTAHDKDSGPNA 2319 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777 ++ YSI G+ ++F + +D ++ LD E+ + Y LV+ PPL + Sbjct: 2320 MLKYSIHSGNTDDAFVII----ADSGDISLDKPLDKET-IENYTLVLIVTDMGIPPLESI 2374 Query: 778 VR--VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT--DKLQYRIL 832 R V ++V+ VN++AP + + + + P+G RV A + DV+ + Y I Sbjct: 2375 KRMVVNVIVSGVNEHAPRFLN-EFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIK 2433 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ + L+N+ TG +TL+ +L+ + EV D Sbjct: 2434 DAASSKVFLVNQ-TGDITLARELDYETRRRYEFEVFARD 2471 Score = 346 bits (851), Expect = 1e-94 Identities = 256/799 (32%), Positives = 391/799 (48%), Gaps = 60/799 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND+SP+F YE +++E G L + ATD+D N+ + Y+I A+ Sbjct: 1743 IHVYDDNDNSPIFGQTVYEVTLKENYPVGQAFLNVSATDRDSRHNSLLSYSIHDAQANAP 1802 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK--VARYTVLVKATDQASPVSD 128 + FRI +G L +SLD E V R+TV+ A D S S Sbjct: 1803 H------------------FRITDETGELRLSSSLDYEARDVFRFTVI--ARDHGS--SP 1840 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R+ +T + V + D NDN P F Y ++ E++ + PV+ + A D D +N+ ++ Sbjct: 1841 RMGTTL-VQVLVQDVNDNRPMFDPYCYNTTISENL-LPGMPVVW-VSAYDNDSSSNADLK 1897 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLIN 246 Y I GN + F I + +G + V LD+E+ Y L I +D G P+ + +LI+ Sbjct: 1898 YRISAGNKENAFEITA-TGQIRPVIALDHERTGFYNLTIDVRDSGQPALHAMHPATVLIH 1956 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDNAP F +L+ + E+ +G +++ V A D D +NA +TY++ ++ D Sbjct: 1957 VFDVNDNAPIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVS--FSTESD 2014 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ID +G V +S + D ETQ Y V A D G P RSA AT F Sbjct: 2015 Y-FVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIF 2073 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLIT 424 P +YE ++E+ P GT V + A D D + L Y I GN G F+I N G I Sbjct: 2074 QPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGSFTI--DNSTGEIM 2131 Query: 425 VAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + DF++ RY LT+S +D+G + A V I + D N+ P F YTA+V+E Sbjct: 2132 TRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYE 2191 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + +G + V A+D D +N ITYS++S S +FVI+ G ++ D Sbjct: 2192 NFTVGDNLFTVKASDKDSHLNGLITYSITSAPSFAG------KFVIDEILGNVSITSGFD 2245 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E Y + ARD G P + ++++DVNDN PVF + E VGT V Sbjct: 2246 FELEQSYDFVIEARDSGSPPHTAYAHAHVTILDVNDNAPVFPVNNTHLVLTEATEVGTVV 2305 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +V A D D G N + Y + + ++ +FVI SG I +K LD+E++ + L + Sbjct: 2306 LRVTAHDKDSGPNAMLKYSIHSGNTDD-AFVIIADSGDISLDKPLDKETIENYTLVLIVT 2364 Query: 661 DGGTPPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 D G PP S ++V++ + +N+ P F ++ I EN P+GT+I +RA + D Sbjct: 2365 DMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSV 2424 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP-PL 774 A Y IK S F + + ++ +LDYE+ R++YE + A +P P Sbjct: 2425 GARFIYVIKDAASSKVFLV-----NQTGDITLARELDYET-RRRYEFEVFARDDGTPEPR 2478 Query: 775 WNDVRVEILVTDVNDNAPV 793 V I + D+NDN PV Sbjct: 2479 EGLCVVTISLLDINDNRPV 2497 Score = 334 bits (822), Expect = 4e-91 Identities = 255/822 (31%), Positives = 404/822 (49%), Gaps = 73/822 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I ++D ND+ P F +Y + E + GTTV L A+D D N +V ++I +D Sbjct: 4933 RITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQLTASDLDSSLNGKVLFSILEGNSD- 4991 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID +G + T SLD E V YT++++ATD P + Sbjct: 4992 ------------------GKFSIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNS 5033 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIR 188 S +HV++++ NDN P FS+K Y+ S+DE+ +V VI +++ATD D V ++S + Sbjct: 5034 -SQPGMLHVSVVNINDNSPVFSQKIYSASIDENTTV--GHVILRVQATDRDHVNSSSIVI 5090 Query: 189 YAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG----------GSPS 236 Y++ +T+ F+I++ +G++ LV +LDYE + Y+ + A D G + Sbjct: 5091 YSLDQSDTEAMRYFAINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKNRDIGDQA 5150 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 R + I+I D+NDN P+F + ++E I+ +QA DAD G+NA+L Y++ Sbjct: 5151 RVAAVLIDISILDINDNRPKFPQPYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI 5210 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXX 354 + G T+DP +G + TS +LDRET +Y L +T D GDP +A TAT Sbjct: 5211 LNTTSNGT----FTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQTATVSI 5266 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRF 412 F Y V + E+ G ++ L A D DE + + Y + RF Sbjct: 5267 TVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAEILYFLKDVIASKRF 5326 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470 S+ G+ IT+ Q +D+++ Y V A+DSG + ++ V+I I D N+ P F Sbjct: 5327 SMNDTTGQ--ITIKQAVDYEERSSYSFEVFASDSGEARLTGSSSVRIPIIDVNDNRPYFL 5384 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y + E+ IGTTV V A+D D +N ++ +S+ + D +FVI+ T Sbjct: 5385 PTRYYVQLVENVAIGTTVTQVYASDLDSSLNGKVLFSILE-------GNSDGKFVIDQNT 5437 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588 G +TTNK LD E ++ Y L + A D G P L+ + + +SVV++NDN PVF Q++Y+A Sbjct: 5438 GVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNIPVFSQKMYSA 5497 Query: 589 NIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALD 646 +I E+ +VG + +V ATD D V + + Y LD D E F I+ +G + +LD Sbjct: 5498 SIDENTMVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRYFTINNQTGELILVSSLD 5557 Query: 647 RESVATHDLKAVAIDGGTPPQS-------STVIVHIKIEDINDSPPVFESDCLTFYISEN 699 ES + A+D +S + + I + +IND+ P F ++EN Sbjct: 5558 YESTKRYQFTVFALDNAMRSRSRRDSSNLGSCEIEISLGNINDNRPYFSPVEYNIEVAEN 5617 Query: 700 SPIGTTIGEIRAHDPDE-GP-NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 GT++ + A D D+ P N V +++ S S L L++E Sbjct: 5618 VSPGTSLLLLHARDLDDVNPDNPDVIFTMIEQQPSLSMEQSIFAIQRDGTLSLNRTLNFE 5677 Query: 758 SPRKKYELVIRAAS---PPLWNDVR--VEILVTDVNDNAPVM 794 R Y + I A PPL V V ++V D ND P + Sbjct: 5678 E-RSSYNVTIAVADNGVPPLRCLVPAVVRVMVVDYNDGVPFL 5718 Score = 309 bits (759), Expect = 2e-83 Identities = 252/876 (28%), Positives = 402/876 (45%), Gaps = 86/876 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ V D ND+ P+F+ Y ++ E G V+ + A D D NA+++Y I Sbjct: 1848 QVLVQDVNDNRPMFDPYCYNTTISENLLPGMPVVWVSAYDNDSSSNADLKYRISAG---- 1903 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E+A F I +G + +LD E+ Y + + D P Sbjct: 1904 -NKENA--------------FEITA-TGQIRPVIALDHERTGFYNLTIDVRDSGQPALHA 1947 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + AT+ +++ D NDN P F++ Y+ + ED +V + + A D D N+ + Y Sbjct: 1948 MHP-ATVLIHVFDVNDNAPIFNQTLYSAIIPEDFTV--GGTLLTVLARDQDAALNARVTY 2004 Query: 190 AIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +I+ +T+ F ID+++G V K DYE R Y +RA+D GSP RS + + I Sbjct: 2005 SIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQIT 2064 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P F ++ VSEN P+G + RV+A D D NA+L Y++ + GN + Sbjct: 2065 DTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQN----GNNNGS 2120 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXF 366 TID +G + T + D E +Y L ++ +D G P S+ A F Sbjct: 2121 FTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEF 2180 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT-RGRFSITSQNGRGLI 423 +Y + E+ G + T+ A+D D + + Y IT + G+F I G + Sbjct: 2181 AQKRYTATVYENFTVGDNLFTVKASDKDSHLNGLITYSITSAPSFAGKFVIDEILGN--V 2238 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFED 481 ++ DF+ E+ Y + A DSG TA ++T D N+ APVF + E Sbjct: 2239 SITSGFDFELEQSYDFVIEARDSGSPPHTAYAHAHVTILDVNDNAPVFPVNNTHLVLTEA 2298 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +GT VL V+A D D G NA + YS+ S + D FVI +G I+ +K LD+ Sbjct: 2299 TEVGTVVLRVTAHDKDSGPNAMLKYSIHS-------GNTDDAFVIIADSGDISLDKPLDK 2351 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTANIMEDALVGTS 599 ET+ Y L + D G+P L + ++V+ VN++ P F + Y A+I E+ +GTS Sbjct: 2352 ETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTS 2411 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + +V A + DV + R Y + KD + +G I + LD E+ ++ + A Sbjct: 2412 IVRVRAVEDDVSVGARFIYVI--KDAASSKVFLVNQTGDITLARELDYETRRRYEFEVFA 2469 Query: 660 IDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 D GTP P+ +V I + DIND+ PVF + ISE+ +G+T+G I +D Sbjct: 2470 RDDGTPEPREGLCVVTISLLDINDNRPVFTKGENSISISEDVRVGSTLGFIIVND----- 2524 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 S ET + +T+V D SPR + + P V Sbjct: 2525 ---------------SLDFETTASYN----LTIVAFDSGSPR------LASLVPA---TV 2556 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836 V++L D NDN P+ + Y++ + A+D D + ++ Y I++ + Sbjct: 2557 FVKVL--DANDNPPIFNQSEYYVEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSV 2614 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + N TTG ++L+ +L+ M V DG Sbjct: 2615 KGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDG 2650 Score = 285 bits (700), Expect = 3e-76 Identities = 219/756 (28%), Positives = 361/756 (47%), Gaps = 63/756 (8%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60 S P +H ++V++ ND+SPVF + Y AS+ E + G +L ++ATD+D + ++ V Y Sbjct: 5034 SQPGMLH--VSVVNINDNSPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNSSSIVIY 5091 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 +++ +DT F I+ ++G L+ +SLD E Y V A Sbjct: 5092 SLD--QSDT---------------EAMRYFAINNQTGELILVSSLDYESTKGYQFTVFAG 5134 Query: 121 DQAS------PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 D + + D+ A I ++I+D NDN P+F + + + E ++ +I Sbjct: 5135 DNIAQFRKNRDIGDQARVAAVLIDISILDINDNRPKFPQPYNKIEITE--GTRESTMILT 5192 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 ++ATDAD G N+ + Y+I+ + F++D +G + + LD E V Y L I D G Sbjct: 5193 LQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 5252 Query: 234 SP--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 P + + T + I + D NDN P F ++ S+ EN+ +G I+ + A D DEGVNAE Sbjct: 5253 DPMLNAAQTATVSITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAE 5312 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + Y + KD + +++ +G + +D E ++ Y V A+D G+ + +++ Sbjct: 5313 ILYFL--KDVIAS--KRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDSGEARLTGSSS 5368 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409 F+P +Y V+L E+ GT V + A+D D + ++ + I GN+ Sbjct: 5369 VRIPIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVYASDLDSSLNGKVLFSILEGNSD 5428 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465 G+F + QN G++T + LD++ Y L + ATD G S M+ +++ + N+ Sbjct: 5429 GKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 5486 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524 PVF Y+AS+ E+ +G +L V ATD D V ++ + YSL + EA+ + F Sbjct: 5487 IPVFSQKMYSASIDENTMVGHVILRVQATDRDHVNSSSIVIYSL-DQSDTEAMRY----F 5541 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-------DTTDVEISVVDVNDN 577 IN QTG + LD E+ Y TV A D + S S + ++EIS+ ++NDN Sbjct: 5542 TINNQTGELILVSSLDYESTKRYQFTVFALDNAMRSRSRRDSSNLGSCEIEISLGNINDN 5601 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDA-DVGL-NGRIHY---ELDPKDREEGSFVI 632 P F Y + E+ GTS+ + A D DV N + + E P E S Sbjct: 5602 RPYFSPVEYNIEVAENVSPGTSLLLLHARDLDDVNPDNPDVIFTMIEQQPSLSMEQSIFA 5661 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV--IVHIKIEDINDSPPVFESD 690 G + N+ L+ E +++++ D G PP V +V + + D ND P S Sbjct: 5662 IQRDGTLSLNRTLNFEERSSYNVTIAVADNGVPPLRCLVPAVVRVMVVDYNDGVPFLTSP 5721 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 I S GT I+A D D G + Y I Sbjct: 5722 TGVILIDWASSPGTIATVIQASDHDSGSAGFISYFI 5757 Score = 276 bits (677), Expect = 2e-73 Identities = 249/898 (27%), Positives = 395/898 (43%), Gaps = 54/898 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ PVF YEA V +KA D D +N + Y++ + Sbjct: 1181 IRIRDDNDNQPVFSRDLYEAWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSKFR 1240 Query: 71 NPEDAXXXXXXXXXXVQD----VFRIDGRSGALLTRASLDREKVARYTV----------L 116 E ++ VF I + ++S KV V L Sbjct: 1241 VNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFL 1300 Query: 117 VKAT-DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK 175 K+T + SPV + + + I D+NDN P F Y V + E++S+ + I ++ Sbjct: 1301 YKSTVRENSPVGTTAIKVSVVLL-IEDENDNPPVFDLPYYFVRMYENVSIRAD--IIRVH 1357 Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 A+D+D G NS IRY+ G F+I++ +G + +D+E+ R Y + A D G P Sbjct: 1358 ASDSDSGFNSEIRYSFPVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIP 1417 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 + + +++ DVNDN P F + + +VSE + G IV + + D D N + + Sbjct: 1418 VLRDVAIVRVDVLDVNDNPPEFLRTQYDVTVSEALLPGSIIVTLVSRDNDSTANGLVRFD 1477 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXX 353 + D N +T SG + + LD E +Y LL+ A D G PP AT Sbjct: 1478 ILSGD--KNSTFRVT---ESGSIILNKSLDYEQTKEYTLLLRARDVGLPPLVSDRNATVL 1532 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RF 412 F QY E+ G+ ++ + ATD D + H ++G F Sbjct: 1533 IRVVDLNDHQPVFDLSQYSGVFMENTSVGSSLLRVRATDQDSNMNSHISYYMNTSQGLPF 1592 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470 + NG IT+ + LDF+ Y V A+D+G ++ +VQI + D N+ APVF Sbjct: 1593 DVNQTNGE--ITLIRALDFETRSFYSFIVVASDAGRNRKAVNTLVQIYVMDINDNAPVFF 1650 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y ++ E G + V+A D+D NAQ+ +++S NE + F IN Sbjct: 1651 PIVYDVTISEATLQGAIIAKVTANDNDSLSNAQLRFAISQ--GNE-----NGSFAIN-DA 1702 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTA 588 G + +D E Y LT+T D G P L S V I V D NDN P+F Q +Y Sbjct: 1703 GILILAHAIDFENTRMYDLTITVHDLGWPPLATSKPARVIIHVYDDNDNSPIFGQTVYEV 1762 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + E+ VG + V ATD D N + Y + F I +G +R + +LD E Sbjct: 1763 TLKENYPVGQAFLNVSATDRDSRHNSLLSYSIHDAQANAPHFRITDETGELRLSSSLDYE 1822 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + +A D G+ P+ T +V + ++D+ND+ P+F+ C ISEN G + Sbjct: 1823 ARDVFRFTVIARDHGSSPRMGTTLVQVLVQDVNDNRPMFDPYCYNTTISENLLPGMPVVW 1882 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI- 767 + A+D D NA + Y I G+ N+F + T G ++ ++ LD+E Y L I Sbjct: 1883 VSAYDNDSSSNADLKYRISAGNKENAFEI-TATG----QIRPVIALDHER-TGFYNLTID 1936 Query: 768 -RAASPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822 R + P + V I V DVNDNAP+ +D G V A D D Sbjct: 1937 VRDSGQPALHAMHPATVLIHVFDVNDNAPIFNQTLYSAIIPEDFTVGGTLLTVLARDQDA 1996 Query: 823 -VTDKLQYRILS-GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 + ++ Y I+S ++ +++ TG + S + + ++ + V D + I++ Sbjct: 1997 ALNARVTYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRS 2054 Score = 226 bits (553), Expect = 2e-58 Identities = 161/511 (31%), Positives = 246/511 (48%), Gaps = 40/511 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH QI D ND+ P+F+ +YE V E GT V +KA D+D NA++ Y+I+ Sbjct: 2059 IHVQIT--DTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQ--- 2113 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 N + F ID +G ++TR D EK RY + + +D P Sbjct: 2114 ----NGNN------------NGSFTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPA 2157 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L + A + + ++D+NDN P+F++K YT +V E+ +V DN + +KA+D D N Sbjct: 2158 LSSL-NFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGDN--LFTVKASDKDSHLNGL 2214 Query: 187 IRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I Y+I + +F ID + G+VS+ D+E +SY VI A+D GSP + + Sbjct: 2215 ITYSITSAPSFAGKFVIDEILGNVSITSGFDFELEQSYDFVIEARDSGSPPHTAYAHAHV 2274 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I DVNDNAP F + ++E +G ++RV A+D D G NA L Y++ ++GN Sbjct: 2275 TILDVNDNAPVFPVNNTHLVLTEATEVGTVVLRVTAHDKDSGPNAMLKYSI----HSGNT 2330 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXX 363 D I SG + LD+ET Y L++ TD G PP + Sbjct: 2331 DDAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHA 2390 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG 421 F+ Y + E+ P GT +V + A + D R Y I + F + N G Sbjct: 2391 PRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLV---NQTG 2447 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478 IT+A+ LD++ RRY V A D G R +V I++ D N+ PVF + S+ Sbjct: 2448 DITLARELDYETRRRYEFEVFARDDGTPEPREGLCVVTISLLDINDNRPVFTKGENSISI 2507 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 ED +G+T+ + DS + +Y+L+ Sbjct: 2508 SEDVRVGSTLGFIIVNDS-LDFETTASYNLT 2537 Score = 206 bits (502), Expect = 3e-52 Identities = 162/588 (27%), Positives = 282/588 (47%), Gaps = 56/588 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+ PVF+ + Y S+ E + G +L L A D+D G NAE+ Y ++ V A Sbjct: 5266 ITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAEILYFLKDVIASKR 5325 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ++ +G + + ++D E+ + Y+ V A+D RL Sbjct: 5326 -------------------FSMNDTTGQITIKQAVDYEERSSYSFEVFASDSGEA---RL 5363 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + ++++ + IID NDN P F Y V + E++++ + ++ A+D D N + ++ Sbjct: 5364 TGSSSVRIPIIDVNDNRPYFLPTRYYVQLVENVAI--GTTVTQVYASDLDSSLNGKVLFS 5421 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIR 248 I+ GN+ +F ID +G V+ K+LDYE V Y LVI+A D G P + S L +++ Sbjct: 5422 ILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVV 5481 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 ++NDN P F ++ S+ EN +G+ I+RVQA D D ++ + D+ T + Sbjct: 5482 NINDNIPVFSQKMYSASIDENTMVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRY- 5540 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-------ATATXXXXXXXXXX 361 TI+ ++G + LD E+ +YQ V A D RS + Sbjct: 5541 FTINNQTGELILVSSLDYESTKRYQFTVFALDNAMRSRSRRDSSNLGSCEIEISLGNIND 5600 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-- 419 F P +Y +E+AE+ PGT ++ L A D D+ N + ++ + S++ + Sbjct: 5601 NRPYFSPVEYNIEVAENVSPGTSLLLLHARDLDDVNPDNPDVIFTMIEQQPSLSMEQSIF 5660 Query: 420 ----RGLITVAQPLDFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPVFEN 471 G +++ + L+F++ Y +T++ D+G A+V++ + D N+ P + Sbjct: 5661 AIQRDGTLSLNRTLNFEERSSYNVTIAVADNGVPPLRCLVPAVVRVMVVDYNDGVPFLTS 5720 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS-------EISNEAVAHHDQQ- 523 + + GT V+ A+D D G I+Y +S+ S++ +Q Sbjct: 5721 PTGVILIDWASSPGTIATVIQASDHDSGSAGFISYFISNITGLPTLTTSSDFARCVNQTY 5780 Query: 524 --FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 F I+ TG + + +L + Y +TVTARD GVP LS + ++I Sbjct: 5781 GVFDIHEHTGTLRVSGILASSCL--YNVTVTARDHGVPPLSSSVILQI 5826 Score = 163 bits (395), Expect = 2e-39 Identities = 161/603 (26%), Positives = 268/603 (44%), Gaps = 61/603 (10%) Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYE 372 SG + + +LD E Y L V A D G P + A F YE Sbjct: 1140 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYE 1199 Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + + + A DAD ++ RL Y + N++ R + T+ G I +++ LD Sbjct: 1200 AWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSKFRVNETT----GEIYLSESLD 1255 Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 F++ + YV + A+DSG +S + V++ + N+ P F+ Y ++V E++P+GTT Sbjct: 1256 FEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFLYKSTVRENSPVGTTA 1315 Query: 489 LVVSAT-----DSD-----------------VGINAQITYSLSSE----ISNEAVAHHDQ 522 + VS ++D V I A I +S+ ++E Sbjct: 1316 IKVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDSDSGFNSEIRYSFPV 1375 Query: 523 QFVINP-----QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 FV+ P TG I T +D E Y +V A D G+P L D V + V+DVNDN Sbjct: 1376 GFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIPVLRDVAIVRVDVLDVNDN 1435 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F + Y + E L G+ + + + D D NG + +++ D+ V + SG Sbjct: 1436 PPEFLRTQYDVTVSEALLPGSIIVTLVSRDNDSTANGLVRFDILSGDKNSTFRVTE--SG 1493 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSS--TVIVHIKIEDINDSPPVFESDCLTFY 695 I NK+LD E + L A D G PP S V I++ D+ND PVF+ + Sbjct: 1494 SIILNKSLDYEQTKEYTLLLRARDVGLPPLVSDRNATVLIRVVDLNDHQPVFDLSQYSGV 1553 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 EN+ +G+++ +RA D D N+ + Y + + S + Q + + L+ LD Sbjct: 1554 FMENTSVGSSLLRVRATDQDSNMNSHISYYM---NTSQGLPFDVNQTNGEITLIRA--LD 1608 Query: 756 YESPRKKYELVIRAASPPLWN---DVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVG 811 +E+ R Y ++ A+ + V+I V D+NDNAPV F I+++ + G Sbjct: 1609 FET-RSFYSFIVVASDAGRNRKAVNTLVQIYVMDINDNAPVF--FPIVYDVTISEATLQG 1665 Query: 812 P-FGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 +V A D D +L++ I GN +N+ G + L+ ++ ++ + ++ Sbjct: 1666 AIIAKVTANDNDSLSNAQLRFAISQGNENGSFAIND-AGILILAHAIDFENTRMYDLTIT 1724 Query: 869 VTD 871 V D Sbjct: 1725 VHD 1727 Score = 104 bits (250), Expect = 9e-22 Identities = 60/184 (32%), Positives = 97/184 (52%), Gaps = 5/184 (2%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 SG + LD E++ Y + V A D PV L A + + I DDNDN P FS Y Sbjct: 1140 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKP-ANVVIRIRDDNDNQPVFSRDLY 1198 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215 V + PV +KA DAD N + Y+++ N++ F ++ +G++ L ++L Sbjct: 1199 EAWVL--VEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSK--FRVNETTGEIYLSESL 1254 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D+E+ + Y I A D G +S++T + + + VNDN P F L++ +V EN P+G + Sbjct: 1255 DFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFLYKSTVRENSPVGTT 1314 Query: 276 IVRV 279 ++V Sbjct: 1315 AIKV 1318 Score = 90.2 bits (214), Expect = 2e-17 Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%) Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANN 464 RGR + N G I++A+ LD+++ + Y LTV A DSG A V I I D N+ Sbjct: 1130 RGRGHLLLVNS-GEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDND 1188 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 PVF Y A V + + A D+D N ++ YS+ ++ +F Sbjct: 1189 NQPVFSRDLYEAWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSM---------VRNNSKF 1239 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 +N TG I ++ LD E Y+ + A D GV S +T V++ V+ VNDN P F + Sbjct: 1240 RVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRF 1299 Query: 585 LYTANIMEDALVGTSVSQV 603 LY + + E++ VGT+ +V Sbjct: 1300 LYKSTVRENSPVGTTAIKV 1318 Score = 73.7 bits (173), Expect = 2e-12 Identities = 52/193 (26%), Positives = 86/193 (44%), Gaps = 8/193 (4%) Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT--TQLLINIRDVNDNAPRFYTSLFQ 263 SG++S+ + LDYE+++ Y L + A D G P + ++I IRD NDN P F L++ Sbjct: 1140 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYE 1199 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 V ++A DAD N L Y+M + ++ +G +Y S Sbjct: 1200 AWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSK------FRVNETTGEIYLSES 1253 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LD E +Y + A+D G P+S++ + F Y+ + E+ P GT Sbjct: 1254 LDFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFLYKSTVRENSPVGT 1313 Query: 384 PVVTLTATDADED 396 + ++ ED Sbjct: 1314 TAIKVSVVLLIED 1326 >SB_38622| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3824 Score = 385 bits (947), Expect = e-106 Identities = 284/886 (32%), Positives = 427/886 (48%), Gaps = 70/886 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+ D ND+ P F Y AS+ E + SG+ V+ L A D DIG+N+ + Y+I L Sbjct: 665 VNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI-------L 717 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F +D R G + +LD E + YT V ATD Sbjct: 718 TPNTP--------------FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGR----- 758 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S AT+HV++ D NDN P F +Y+V E+ + + I ++KA D D + R+ Sbjct: 759 SCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS--ICQLKAIDRDSPKFAITRFI 816 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN FS+D SG ++L K LD E +Y L ++A DGG N + I + DV Sbjct: 817 IEQGNADEVFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDV 875 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND P F + + ++ E+ I V A D+G NAE+ Y+++ GN D + Sbjct: 876 NDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISK----GNTDNIVL 931 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G +Y ++D E L V A D G PP A F Sbjct: 932 INS-TGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSS 990 Query: 371 YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V L ED P G T++ DAD R+ + + N F++ S G +++ + Sbjct: 991 ILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLS-NPGTLFNLDSNTGA--LSLTKL 1047 Query: 429 LDF-KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 +D+ R Y L V A D G RS TAM+++ + D N+Y+PVF N YTA V E P Sbjct: 1048 IDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPD 1107 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + ++ V ATD D G N +I+Y+ S++ +F + G I LDRE + Sbjct: 1108 SNIIEVVATDVDSGENGRISYAFDSKVDTS-------KFGLR-NGGKIFIKSKLDREDIE 1159 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L V A D G P S + DV++ V DVNDN P F+Q Y + E+ V T + V A Sbjct: 1160 EYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSA 1219 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 +D+D G NG + Y D + F++D +G I T++ LDRE+ A++ VA DGG+ Sbjct: 1220 SDSDEGSNGHVTYRFDT---QVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSS 1276 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAVVHY 724 P+ V + + D+ND P F + + ++E+ P+G+++ + A D D+ GPN+ + Y Sbjct: 1277 PRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITY 1336 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI---RAASPPLWNDVRV 780 I G +FSL G ++T+V LD E + V+ + + L + Sbjct: 1337 MIVAGP--KAFSLNQVTG-----VLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYI 1389 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQYRILSGNNA 837 EI V DVNDN PV + + F + P+G V A D+D D K++Y+I++GN Sbjct: 1390 EINVLDVNDNYPVFIN-ETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTD 1448 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQL 882 +NETTG ++ L+ V + VS TD G + K QL Sbjct: 1449 GTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQL 1494 Score = 363 bits (892), Expect = 1e-99 Identities = 281/874 (32%), Positives = 419/874 (47%), Gaps = 64/874 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INV D ND +P F+ YE V E A+ T V + A DQD G N+E+ YTI A+T Sbjct: 555 RINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTI----ANT 610 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID SG + T LDRE++ + + V D+ SP Sbjct: 611 TESRSYLHW-----------FAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPP--- 656 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS ++ VN+ D NDN P F++ +Y S+ E+ S + +PV+ ++ A D D+G NS I Y Sbjct: 657 LSDNCSVIVNLTDSNDNDPYFNQSSYNASLFEN-SPSGSPVV-QLLAQDPDIGENSLILY 714 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I+ NT F +D G V+ +TLD+E SY + A DGG S + T +++ D Sbjct: 715 SILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVH--VSLTD 770 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P F S + EN IG SI +++A D D A + + GN D Sbjct: 771 LNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQ----GNADEVF 826 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ++D SG + + LDRETQ Y L V A DGG A F Sbjct: 827 SVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKA 885 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427 +Y + E + + + A D+ Y I+ GNT +I N G + + Sbjct: 886 EYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTD---NIVLINSTGTLYLQS 942 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 +D ++ LTV A D G A V I + D N+ +P F ++ + ED PIG Sbjct: 943 EVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIG 1002 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR-ETM 544 T VS D+D G+ ++++SL +SN F ++ TGA++ KL+D + Sbjct: 1003 HTFYTVSVFDADSGVLGRVSFSL---LSNPGTL-----FNLDSNTGALSLTKLIDYGNSA 1054 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y L V A+DGG P S T +E+ VVDVND PVF YTA+++E +++ +V Sbjct: 1055 RSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVV 1114 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D G NGRI Y D K + F + + +K LDRE + ++LK +AID GT Sbjct: 1115 ATDVDSGENGRISYAFDSKV-DTSKFGLRNGGKIFIKSK-LDREDIEEYNLKVIAIDHGT 1172 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P +SS+ V + ++D+ND+ P F+ F++ EN P+ T +G + A D DEG N H Sbjct: 1173 PRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNG--HV 1230 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 + + F ++ + G ++ T LD E+ + Y I A S P + +V Sbjct: 1231 TYRFDTQVAQFIVDKQTG----KITTSQVLDREA-KASYVFSIVATDGGSSPRVDKTQVT 1285 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD---VTDKLQYRILSGNNA 837 ++V DVND +P + +D PVG + A D D + Y I++G A Sbjct: 1286 VIVRDVNDCSPKFSKNKYSVTVNED-LPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKA 1344 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 LN+ TG +TL L+ V + V +D Sbjct: 1345 --FSLNQVTGVLTLVSPLDREVTHRHILHVVASD 1376 Score = 359 bits (883), Expect = 2e-98 Identities = 252/821 (30%), Positives = 395/821 (48%), Gaps = 49/821 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F Y ++ E GT++L + A+D+DIG NAE++Y+IE + Sbjct: 339 ITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHS---- 394 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P Q +F I +G ++ LD E Y ++VKA D+ S S +L Sbjct: 395 DP--------------QAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGS--SHQL 438 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGANSAIR 188 SS+A + + ++D NDN P +YT+ + + T +A++ +DAD G N + Sbjct: 439 SSSAIVRIEVLDVNDNNPVI-HVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVN 497 Query: 189 YAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + GG+ D L+ + +++ ++LD E + L D G P R+ IN Sbjct: 498 VTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRIN 557 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVND AP+F ++ V EN + + V A D D G N+EL YT+ + + + Sbjct: 558 VGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYL 617 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 IDP SG + T+ LDRE + L V D G PP S + F Sbjct: 618 HWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYF 677 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y L E+ P G+PVV L A D D E++ + Y I NT F + + +GL+T Sbjct: 678 NQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNT--PFFLDPR--KGLVT 733 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 ++ LD + + Y V+ATD GGRS A V +++TD N+ PVF+ + Y+ FE+ I Sbjct: 734 NSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRI 793 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G ++ + A D D ++++ I + A D+ F ++ +G IT KLLDRET Sbjct: 794 GQSICQLKAIDRD-----SPKFAITRFIIEQGNA--DEVFSVD-GSGLITLAKLLDRETQ 845 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 YLLTV A DGG + V I+V+DVND P+F + Y I E + + + V Sbjct: 846 DNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVH 905 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A D G N + Y + + + + V+ ++G + +D E + + L A D GT Sbjct: 906 AISRDKGTNAEVVYSISKGNTD--NIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGT 963 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 PP V I + DIND+ P F S + + E++PIG T + D D G V + Sbjct: 964 PPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSF 1023 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 S+ + F+L++ G+ L ++ DY + + Y L ++A SPP + +E Sbjct: 1024 SLL-SNPGTLFNLDSNTGA--LSLTKLI--DYGNSARSYTLPVQAQDGGSPPRSSTAMLE 1078 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 + V DVND +PV ++ + + P V A D D Sbjct: 1079 LKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVD 1119 Score = 356 bits (876), Expect = 1e-97 Identities = 272/876 (31%), Positives = 412/876 (47%), Gaps = 60/876 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F+ + E T V T+KA D D G N+ + YTI D+ Sbjct: 1497 IYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTI-----DSQ 1551 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P F+I+ +G + T +DRE+++ Y++ V+ATDQA DRL Sbjct: 1552 SPRAH--------------FKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRL 1597 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +TAT+ + I D NDN P+F + T ++++ N + I A D D G + Y Sbjct: 1598 YNTATLKIIIQDLNDNAPKFVSRNLTYVMEDE---PFNFQVTSITALDPDTGQGGNVEYR 1654 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ +T +FS+D +G + L+ +LDYE V Y L I A D GSP ++ + + DV Sbjct: 1655 IVSPDTG-KFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDV 1713 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F LF +VSEN P G S+V+V AYD D G NAELTY++ +G + Sbjct: 1714 NDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIP----SGVEMDKFS 1769 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID SG + T+ LDRE + Y L V AT P R ++ + F+ Sbjct: 1770 IDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPV 1829 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 +++ E+ P + TLT D D N ++ Y I GNT G F+I G ++ Sbjct: 1830 VTLKVPENS-PARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGE--LSTTTK 1886 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + Y L+V A D TA I I D N+ PVF+ + Y++++ E P GT Sbjct: 1887 LDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGT 1946 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 ++L ++A+D D G N I Y+LS++ + I+ +TG + + + Sbjct: 1947 SILNLTASDKDSGSNGNIVYTLSNDTYG--------VYSIDSRTGIVYSAARFETSIKQE 1998 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y A+D G V I + D N++ P F + Y +I + V+ V AT Sbjct: 1999 YNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTAT 2058 Query: 607 DADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 DAD NG++ Y LD FV++ +G +RT+ H L +A D G+ Sbjct: 2059 DADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGS 2118 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 PP IV I I +I D PP F + I ENS +G+ I +RA +A V Sbjct: 2119 PPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR---ASSDAQVT 2175 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---- 779 YSI G+ +F ++ G + + LDYES K + L + A+P W + Sbjct: 2176 YSIISGNKGRAFYVDPFTG--VISVASADALDYES-TKNFRLHL-VATPQGWVSLNGYMI 2231 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDAD--VTDKLQYRILSGN 835 ++I V D NDN+P ++ +D P +V A D D K+ Y I +GN Sbjct: 2232 LDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGN 2291 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 A + ++ TTG +T + L+ + + TD Sbjct: 2292 EAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTD 2327 Score = 351 bits (863), Expect = 5e-96 Identities = 265/876 (30%), Positives = 396/876 (45%), Gaps = 60/876 (6%) Query: 10 QINVLDCNDHSPVFEMQQY---EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +I VLD ND++PV + V E A+ GT V + +D D GKN EV T+E Sbjct: 445 RIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLE--- 501 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 F + + SLDRE + + D+ P Sbjct: 502 --------------GGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPP 547 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 ++ + +N+ D ND P+F TY V E+ +V N ++A + A D D G+NS Sbjct: 548 R---TTEKSFRINVGDVNDCAPKFDRHTYETRVWENATV--NTLVAIVNAVDQDFGSNSE 602 Query: 187 IRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + Y I F+ID SG ++ LD EQ+ L + D GSP S+ Sbjct: 603 LVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCS 662 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 +++N+ D NDN P F S + S+ EN P G +V++ A D D G N+ + Y++ T Sbjct: 663 VIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI----LT 718 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 N P +DPR G V S LD E Q+ Y V ATDGG RS AT Sbjct: 719 PNT--PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDN 774 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGR 420 F P Y VE E+ G + L A D D + I GN FS+ +G Sbjct: 775 QPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSV---DGS 831 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASV 478 GLIT+A+ LD + + Y+LTV A D GG+ + A+V I + D N+ P+F A Y ++ Sbjct: 832 GLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTI 891 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E + + + V A D G NA++ YS+S + D +IN TG + Sbjct: 892 QEHSQALSVIGHVHAISRDKGTNAEVVYSISK-------GNTDNIVLIN-STGTLYLQSE 943 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 +D E + LTV A+D G P L +V I+V+D+NDN P F + ED +G Sbjct: 944 VDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGH 1003 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKA 657 + V DAD G+ GR+ + L F +D +G + K +D S ++ L Sbjct: 1004 TFYTVSVFDADSGVLGRVSFSL--LSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPV 1061 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DGG+PP+SST ++ +K+ D+ND PVF + T ++ E +P + I E+ A D D G Sbjct: 1062 QAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSG 1121 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 N + Y+ D++ F L R G K + + +D + + I +P + Sbjct: 1122 ENGRISYAFDSKVDTSKFGL--RNGG-KIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSS 1178 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNN 836 V+++V DVNDN P + F K+ PV + G V A D+D Sbjct: 1179 ADVKVIVDDVNDNNPHFQQASYAF-FVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQ 1237 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++++ TG +T S L+ + TDG Sbjct: 1238 VAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDG 1273 Score = 348 bits (856), Expect = 3e-95 Identities = 271/895 (30%), Positives = 423/895 (47%), Gaps = 59/895 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+SP F ++ A + + L A D D G N+ YTI V+ + Sbjct: 225 VYVQDLNDNSPSF-VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTI--VSGNVG 281 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N D+ ++ S +DRE++ Y + + A+D +P + Sbjct: 282 NVFKLISKRDTDGDLYADLV-VNASS------IGVDRERLDSYVLNISASDGGNPAN--- 331 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + + D NDN P+FS +Y+ ++ E+I V + I ++ A+D D+G N+ I+Y+ Sbjct: 332 HGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTS--ILQVSASDKDIGTNAEIQYS 389 Query: 191 I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIR 248 I + Q F I +G + LDYE RSY +V++A+D GS + +++ ++ I + Sbjct: 390 IETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVL 449 Query: 249 DVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 DVNDN P YT V+EN IG + RV DAD G N E+ T+ D G Sbjct: 450 DVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGD--GYF 507 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + + + LDRET + L D GDPPR+ + Sbjct: 508 SMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPK 567 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS----ITSQNGRG 421 F YE + E+ T V + A D D + T NT S G Sbjct: 568 FDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSG 627 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 +IT A LD +Q + VLTV D G SD V +N+TD+N+ P F + Y AS+F Sbjct: 628 MITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLF 687 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++P G+ V+ + A D D+G N+ I YS+ + + F ++P+ G +T ++ L Sbjct: 688 ENSPSGSPVVQLLAQDPDIGENSLILYSILTP---------NTPFFLDPRKGLVTNSRTL 738 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E S Y V A DGG S + T V +S+ D+NDN+PVF Y+ E+ +G S Sbjct: 739 DHEVQSSYTFQVAATDGGGRSCNAT--VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS 796 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + Q+ A D D + ++ + +E F +D SG+I K LDRE+ + L A Sbjct: 797 ICQLKAIDRDSPKFAITRFIIEQGNADE-VFSVD-GSGLITLAKLLDRETQDNYLLTVKA 854 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 +DGG + IV+I + D+ND PP+F F I E+S + IG + A D+G N Sbjct: 855 VDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTN 914 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 A V YSI G+ N + + L ++D+E Y L ++A +PPL+ Sbjct: 915 AEVVYSISKGNTDNIVLI-----NSTGTLYLQSEVDHEKIPSLY-LTVQAKDKGTPPLFG 968 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILS 833 V I V D+NDN+P I+ +D P+G F V +DAD V ++ + +LS Sbjct: 969 YANVTIAVIDINDNSPQFNSSSILVRLPEDT-PIGHTFYTVSVFDADSGVLGRVSFSLLS 1027 Query: 834 GNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK---AMMQLSV 884 N L L+ TG+++L+ ++ N + T+ V DG + + AM++L V Sbjct: 1028 -NPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKV 1081 Score = 339 bits (833), Expect = 2e-92 Identities = 257/856 (30%), Positives = 410/856 (47%), Gaps = 63/856 (7%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTADTLN 71 V D ND SP F +Y +V E G+++LTL ATD D G N+++ Y I Sbjct: 1288 VRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMI------VAG 1341 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 P+ F ++ +G L + LDRE R+ + V A+D+ S L Sbjct: 1342 PK---------------AFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQS--LE 1384 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 + I +N++D NDNYP F +T +V E + + V+A + A D+D G N +RY I Sbjct: 1385 TITYIEINVLDVNDNYPVFINETTFKTVPEKLPI--GSVVAAVLAVDSDQGDNGKVRYKI 1442 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDV 250 + GNT F I+ +G +S ++ LD+E Y L + A D G + + QL+ I + D Sbjct: 1443 VNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDA 1502 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + ENVPI ++ ++A+D D G+N+ + YT+ + + Sbjct: 1503 NDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAH----FK 1558 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA---TATXXXXXXXXXXXXXXFM 367 I+ +G + T+ +DRE ++Y L V ATD + TAT F+ Sbjct: 1559 INSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFV 1618 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 + + EDEP V ++TA D D + + Y I +T G+FS+ + G++ + Sbjct: 1619 -SRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDT-GKFSLDLKT--GVLKL 1674 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAP 483 LD++ +Y L +SATD G T+ + + + D N+ P F + +V E+ P Sbjct: 1675 IGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKP 1734 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT+V+ V+A D D G NA++TYS+ S + + +F I+ +G I TN +LDRE Sbjct: 1735 TGTSVVKVTAYDRDSGSNAELTYSIPSGVEMD-------KFSIDKHSGLIVTNSILDREK 1787 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y LTV A P +T V I+V+D NDN P F + T + E++ + + Sbjct: 1788 KDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS-PARLIYTL 1846 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D D G N ++ Y + +G+F I ++G + T LDRE+ A++ L A D Sbjct: 1847 TVQDLDYGNNTKVLYSI-MSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDIT 1905 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P ++ + I IED ND+PPVF+ + ISE +P GT+I + A D D G N + Sbjct: 1906 PPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIV 1965 Query: 724 YSIKGGDDSNSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 Y++ D +S+++R G A T + +Y + + P V V Sbjct: 1966 YTL-SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNF----FCIAKDQGQDPKMAIVPVR 2020 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD----VTDKLQYRI-LSGNN 836 I + D N++AP + + + V A DAD K+ YR+ S N+ Sbjct: 2021 IKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNS 2080 Query: 837 ANLILLNETTGSMTLS 852 +L ++ TGS+ S Sbjct: 2081 TSLFVVESNTGSVRTS 2096 Score = 330 bits (811), Expect = 9e-90 Identities = 244/779 (31%), Positives = 377/779 (48%), Gaps = 43/779 (5%) Query: 90 FRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 F +D +G + ++ LD E + + + AT Q VS L+ + +N+ID NDN Sbjct: 2187 FYVDPFTGVISVASADALDYESTKNFRLHLVATPQGW-VS--LNGYMILDINVIDRNDNS 2243 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F + ED + K+ ATD D G N + Y+I GN F+IDS +G Sbjct: 2244 PAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTG 2303 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +++ K LD E S+ LVIR D G P +S Q+ + + D+NDN P F L + ++ Sbjct: 2304 EITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLF-DPLSEVNIR 2362 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E+ G + V A D D+ + LTY + G ++ +G V +LD E Sbjct: 2363 EDTRTGAVVTSVVATDTDK--ESRLTYNLKSASTPG----MFSVGRFNGAVSLLKRLDYE 2416 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 KY L + +DG SA T F+ Y+V L++ P G ++ Sbjct: 2417 KTNKYSLNIAVSDG---LHSAEKTLTINVLDTNDNTPKFLNSSYQVTLSKTIPAGRAILR 2473 Query: 388 LTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATD 445 ++ATD D + + + T + G+I+ + +D + ++ + V A D Sbjct: 2474 VSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMD 2533 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQI 504 G A+V + I P FE Y V E+A +GT+VL V TD+ G+ +I Sbjct: 2534 QGVPPQRALVYVRIIITRE--PKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRI 2591 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 +Y++ E SN F I ++G I+ NK LD ET +LL V+A D PS Sbjct: 2592 SYNI--ENSN--------YFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVR 2641 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 V I+V DVND +PVF Q Y A E VGT V V A D D G NGR+ + + D Sbjct: 2642 VPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGD 2701 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 ++GSF ID +GVIRT +ALD E++ TH + A D G+PP + V V I++ D+ND+P Sbjct: 2702 -DKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNP 2760 Query: 685 PVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PVF + EN P+ + + EI A D D G NA + +++ GG F ++ G Sbjct: 2761 PVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSG- 2819 Query: 744 DKAELVTMVDLDYESPR-KKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQI 799 L T + DYE+ +Y L I+ A +PPL +++ + + V D ++ P Sbjct: 2820 ---WLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDY 2876 Query: 800 IFNNYKDCFPVGPF-GRVPAYDADVTDKLQ-YRILSGNNANLILLNETTGSMTLSPQLN 856 F+ + +G F G+V A D D D+ + + + +N + +N TTG ++++ LN Sbjct: 2877 KFDVPGNA-KIGDFVGQVTATDRDSGDQGRVFFVFYNPTSNALKMNATTGIISVNRTLN 2934 Score = 327 bits (804), Expect = 7e-89 Identities = 234/796 (29%), Positives = 380/796 (47%), Gaps = 54/796 (6%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 ++ +G + T+ LDREKV+ Y + + + ++P + T+ V + D NDN P F Sbjct: 186 LEYNAGVITTKTVLDREKVSAYNLTI--VEFSTP-----PKSYTVLVYVQDLNDNSPSFV 238 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS---LSGD 208 T V + D K+ A D+D G+NS Y I+ GN F + S GD Sbjct: 239 RGTSAKLV---VFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGD 295 Query: 209 V--SLVKT-----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 + LV +D E++ SY L I A DGG+P+ +L I + D NDN P F Sbjct: 296 LYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVS 355 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + ++ EN+ +G SI++V A D D G NAE+ Y++ + + I P +G + + Sbjct: 356 YSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSI---ETHSDPQAIFGIHPTTGVIVNN 412 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV----ELAE 377 +LD E + Y ++V A D G + +++ + Y + ++ E Sbjct: 413 VRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTE 472 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQPLDFKQER 435 + GT V ++ +DAD +T G FS+ N +I V Q LD + Sbjct: 473 NATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHD 532 Query: 436 RYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + L D G R+ +IN+ D N+ AP F+ Y V+E+A + T V +V+A Sbjct: 533 HFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNA 592 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D D G N+++ Y++++ + + H F I+P +G ITT LDRE + +LTV Sbjct: 593 VDQDFGSNSELVYTIANTTESRSYLHW---FAIDPSSGMITTATDLDREQIPQVVLTVLV 649 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D G P LSD V +++ D NDN+P F Q Y A++ E++ G+ V Q+ A D D+G N Sbjct: 650 HDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGEN 709 Query: 614 GRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 I Y L P F +DP G++ ++ LD E +++ + A DGG +S Sbjct: 710 SLILYSILTPNT----PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGG--GRSCNAT 763 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 VH+ + D+ND+ PVF+ + EN+ IG +I +++A D D A+ + I+ G+ Sbjct: 764 VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNAD 823 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789 FS+ D + L+T+ L + Y L ++A N V I V DVND Sbjct: 824 EVFSV------DGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVND 877 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847 P+ + F + + G V A D ++ Y I GN N++L+N +TG Sbjct: 878 EPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLIN-STG 936 Query: 848 SMTLSPQL-NTNVPKL 862 ++ L ++ + +P L Sbjct: 937 TLYLQSEVDHEKIPSL 952 Score = 316 bits (776), Expect = 2e-85 Identities = 246/805 (30%), Positives = 377/805 (46%), Gaps = 65/805 (8%) Query: 2 SVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59 S P +Q NV+ D ND+ P F + +V E +GT+V+ + A D+D G NAE+ Sbjct: 1697 SPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELT 1756 Query: 60 YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 Y+I P D F ID SG ++T + LDREK Y + V A Sbjct: 1757 YSI---------PSGVE----------MDKFSIDKHSGLIVTNSILDREKKDTYFLTVHA 1797 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 T + P R+SST ++ +N++D NDN P+F T+ V E+ + +I + D Sbjct: 1798 TGVSYPF--RVSST-SVRINVMDRNDNPPKFISPVVTLKVPEN---SPARLIYTLTVQDL 1851 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 D G N+ + Y+I+ GNT F+I +G++S LD E SY+L ++A+D P + Sbjct: 1852 DYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTA 1911 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + I I D NDN P F SL+ ++SE P G SI+ + A D D G N + YT+++ Sbjct: 1912 FANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSND 1971 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 Y +ID R+G VY++ + + + +Y A D G P+ A Sbjct: 1972 TYG-----VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDK 2026 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-----GGNTRGRFSI 414 F YEV + + V +TATDAD D + ++T N+ F + Sbjct: 2027 NNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVV 2086 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN- 471 S G + + + R+ L + A D G +VQI I + + P F N Sbjct: 2087 ESNTGS--VRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQ 2144 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 P S+ E++ +G+ + V A S +AQ+TYS+ S + + F ++P TG Sbjct: 2145 TPARVSIPENSKVGSYITTVRARASS---DAQVTYSIIS-------GNKGRAFYVDPFTG 2194 Query: 532 AIT--TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 I+ + LD E+ + L + A G SL+ ++I+V+D NDN P F A Sbjct: 2195 VISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQ 2254 Query: 590 IMED--ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 + ED A V +V ATD D G NG++ Y + E G F ID +G I T K LDR Sbjct: 2255 LAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSI-WTGNEAGVFTIDSTTGEITTAKLLDR 2313 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E+ A+ DL D G PP+S+ V + + D+ND+PP+F+ I E++ G + Sbjct: 2314 ETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFD-PLSEVNIREDTRTGAVVT 2372 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A D D+ + + Y++K FS+ G + + LDYE KY L I Sbjct: 2373 SVVATDTDK--ESRLTYNLKSASTPGMFSV----GRFNGAVSLLKRLDYEK-TNKYSLNI 2425 Query: 768 RAASPPLWNDVRVEILVTDVNDNAP 792 + + + I V D NDN P Sbjct: 2426 AVSDGLHSAEKTLTINVLDTNDNTP 2450 Score = 310 bits (761), Expect = 1e-83 Identities = 252/856 (29%), Positives = 390/856 (45%), Gaps = 59/856 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INVLD ND+ PVF + +V E G+ V + A D D G N +V Y ++V +T Sbjct: 1390 EINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRY--KIVNGNT 1447 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F+I+ +G + T +LD E RY + V ATD Sbjct: 1448 -----------------DGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKT 1490 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 TI+V D NDN P F + + E++ + N + IKA D D G NS I Y Sbjct: 1491 SYQLVTIYVE--DANDNRPTFDKNPIITWIYENVPINTN--VTTIKAHDDDSGLNSRIWY 1546 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS---NTTQLLIN 246 I + + F I+S +G + +D E++ Y L +RA D + NT L I Sbjct: 1547 TIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKII 1606 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I+D+NDNAP+F S V E+ P + + + A D D G + Y + D TG Sbjct: 1607 IQDLNDNAPKF-VSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPD-TGK-- 1662 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++D ++G + G LD E +Y L ++ATD G PP ++ F Sbjct: 1663 --FSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEF 1720 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLIT 424 + ++E++P GT VV +TA D D + L Y I G +FSI + GLI Sbjct: 1721 TRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHS--GLIV 1778 Query: 425 VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 LD +++ Y LTV AT R + V+IN+ D N+ P F + T V E++ Sbjct: 1779 TNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS 1838 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P + ++ D D G N ++ YS+ S + D F I TG ++T LDRE Sbjct: 1839 P-ARLIYTLTVQDLDYGNNTKVLYSIMS-------GNTDGAFTIGRSTGELSTTTKLDRE 1890 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T + Y L+V A+D P + ++ I + D NDN PVF+Q LY++ I E GTS+ Sbjct: 1891 TKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILN 1950 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + A+D D G NG I Y L + G + ID +G++ + + ++ +A D Sbjct: 1951 LTASDKDSGSNGNIVYTL--SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQ 2008 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNA 720 G P+ + V V IKIED N+ P F +I N+ + + A D D+ N Sbjct: 2009 GQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNG 2068 Query: 721 VVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 V Y + +S S F +E+ GS + T P+ ++ L I A SPPL Sbjct: 2069 KVTYRLDDSKNSTSLFVVESNTGSVR----TSAGFS-NPPQGRHALYIIAEDHGSPPLRG 2123 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836 V+I++ ++ D+ P + + + VG + A ++ Y I+SGN Sbjct: 2124 YGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQVTYSIISGNK 2183 Query: 837 ANLILLNETTGSMTLS 852 ++ TG ++++ Sbjct: 2184 GRAFYVDPFTGVISVA 2199 Score = 306 bits (752), Expect = 1e-82 Identities = 233/743 (31%), Positives = 351/743 (47%), Gaps = 62/743 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVRE--GASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 INV+D ND+SP F A + E GA V+ + ATD D G N +V Y+I Sbjct: 2234 INVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIW----- 2288 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 T N VF ID +G + T LDRE A + ++++ TD P Sbjct: 2289 TGNEAG--------------VFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPK- 2333 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S+ + V + D NDN P F + V++ ED V+ + ATD D S + Sbjct: 2334 --STNCQVKVVVTDLNDNPPLF-DPLSEVNIRED--TRTGAVVTSVVATDTD--KESRLT 2386 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + +T FS+ +G VSL+K LDYE+ Y L I DG S L IN+ Sbjct: 2387 YNLKSASTPGMFSVGRFNGAVSLLKRLDYEKTNKYSLNIAVSDG---LHSAEKTLTINVL 2443 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P+F S +Q ++S+ +P G +I+RV A D D G NA++ Y+ T + + Sbjct: 2444 DTNDNTPKFLNSSYQVTLSKTIPAGRAILRVSATDQDSGSNAQIKYSF---PITNSDQID 2500 Query: 309 ITIDPRSGWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ID +G + +D R + Q+ V A D G PP+ A F Sbjct: 2501 YKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALV----YVRIIITREPKFE 2556 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y ++ E+ GT V+T+ TD R+ Y I N F I ++ G+I+ Sbjct: 2557 LPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSN---YFRIGQRS--GVIS 2611 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDA 482 V +PLD++ +RR++L VSA D S V IN++D N+ PVF + Y A E Sbjct: 2612 VNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGI 2671 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+GT V+ VSA D D G N ++ +++ S F I+ +TG I T + LD E Sbjct: 2672 PVGTIVVNVSAADKDSGANGRVWFAIQS-------GDDKGSFAIDRKTGVIRTQRALDHE 2724 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSVS 601 T+ + ++V A D G P + V I V+D+NDN PVF+ ++E+ + + + Sbjct: 2725 TIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLY 2784 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT--HDLKAVA 659 ++ ATD D G N R+ + + +G F+ID SG + TN D E+ A + L A Sbjct: 2785 EINATDRDSGANARLSFTV-IGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKA 2843 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G PP SS + + + + D ++ P F F + N+ IG +G++ A D D G Sbjct: 2844 TDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQ 2903 Query: 720 AVVHYSIKGGDDSNSFSLETRQG 742 V + + SN+ + G Sbjct: 2904 GRVFF-VFYNPTSNALKMNATTG 2925 Score = 254 bits (622), Expect = 8e-67 Identities = 248/898 (27%), Positives = 401/898 (44%), Gaps = 81/898 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ PVF+ Y +++ E GT++L L A+D+D G N + YT+ + DT Sbjct: 1917 IFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTL---SNDTY 1973 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V+ ID R+G + + A + Y A DQ D Sbjct: 1974 G-----------------VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQG---QDPK 2013 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIR 188 + + + I D N++ PQF++ Y V + + S + ++ + ATDAD N + Sbjct: 2014 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSA--SALVTMVTATDADTDKSTNGKVT 2071 Query: 189 YAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y + N+ F ++S +G V + L I A+D GSP + I I Sbjct: 2072 YRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVI 2131 Query: 248 RDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 ++ D+ PRF + S+ EN +G I V+A + + A++TY++ +GN Sbjct: 2132 GNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSD---AQVTYSI----ISGNKG 2184 Query: 307 LPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +DP +G V ++ LD E+ ++L + AT G + Sbjct: 2185 RAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSP 2244 Query: 365 XFMPGQYEVELAEDEPPGTP--VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420 F P +LAED P VV +TATD D + ++ Y I GN G F+I S G Sbjct: 2245 AFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGE 2304 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 IT A+ LD + + L + TDSG +S V++ +TD N+ P+F+ ++ Sbjct: 2305 --ITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLS-EVNI 2361 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED G V V ATD+D +++TY+L S A F + GA++ K Sbjct: 2362 REDTRTGAVVTSVVATDTDK--ESRLTYNLKS-------ASTPGMFSVGRFNGAVSLLKR 2412 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LD E + Y L + D G+ S T + I+V+D NDN P F Y + + G Sbjct: 2413 LDYEKTNKYSLNIAVSD-GLHSAEKT--LTINVLDTNDNTPKFLNSSYQVTLSKTIPAGR 2469 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKA 657 ++ +V ATD D G N +I Y + ++ + ID +GVI + +D R + + Sbjct: 2470 AILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPV 2529 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A+D G PPQ + V V I I P FE + EN+ +GT++ +R D G Sbjct: 2530 QAMDQGVPPQRALVYVRI----IITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAG 2585 Query: 718 -PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 P + Y+I ++SN F + R G + LDYE+ ++++ LV+ A +P Sbjct: 2586 LPLGRISYNI---ENSNYFRIGQRSG----VISVNKPLDYET-KRRFLLVVSAIDDTAPS 2637 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYR 830 V V I V+DVND PV + + + PVG V A D D ++ + Sbjct: 2638 KPVRVPVYINVSDVNDEKPVFGQSGYM-AQWSEGIPVGTIVVNVSAADKDSGANGRVWFA 2696 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 I SG++ ++ TG + L+ K + V TD G + + +++R++ Sbjct: 2697 IQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVL 2754 Score = 253 bits (619), Expect = 2e-66 Identities = 223/798 (27%), Positives = 346/798 (43%), Gaps = 60/798 (7%) Query: 1 MSVPFCIHQ---QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE 57 +S PF + +INV+D ND+ P F V E S + TL D D G N + Sbjct: 1800 VSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPEN-SPARLIYTLTVQDLDYGNNTK 1858 Query: 58 VEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117 V Y+I ++ +T F I +G L T LDRE A Y + V Sbjct: 1859 VLYSI--MSGNT-----------------DGAFTIGRSTGELSTTTKLDRETKASYQLSV 1899 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177 +A D P ++ A I + I D NDN P F + Y+ ++ E I + A+ Sbjct: 1900 QAKDITPPY---YTAFANITIFIEDQNDNPPVFQQSLYSSTISE--LTPPGTSILNLTAS 1954 Query: 178 DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 D D G+N I Y + +T +SIDS +G V + + Y A+D G + Sbjct: 1955 DKDSGSNGNIVYT-LSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPK 2013 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA--DEGVNAELTYT 295 + I I D N++AP+F + ++ + N + V A DA D+ N ++TY Sbjct: 2014 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYR 2073 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + D + ++ ++ +G V TS Q ++ L + A D G PP Sbjct: 2074 LDDSKNSTSL---FVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIV 2130 Query: 356 XXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414 F+ V + E+ G+ + T+ A A D ++ Y I GN F + Sbjct: 2131 IGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR-ASSDAQVTYSIISGNKGRAFYV 2189 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA 472 G + A LD++ + + L + AT G + ++ IN+ D N+ +P F + Sbjct: 2190 DPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPS 2249 Query: 473 PYTASVFED--APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 A + ED A V+ V+ATD D G N ++TYS+ + NEA F I+ T Sbjct: 2250 NMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWT--GNEAGV-----FTIDSTT 2302 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G ITT KLLDRET + + L + D G+P S V++ V D+NDN P+F L NI Sbjct: 2303 GEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLF-DPLSEVNI 2361 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 ED G V+ V ATD D R+ Y L G F + +G + K LD E Sbjct: 2362 REDTRTGAVVTSVVATDTD--KESRLTYNLKSAS-TPGMFSVGRFNGAVSLLKRLDYEKT 2418 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + L +A+ G T+ +++ D ND+ P F + +S+ P G I + Sbjct: 2419 NKYSLN-IAVSDGLHSAEKTLTINVL--DTNDNTPKFLNSSYQVTLSKTIPAGRAILRVS 2475 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 A D D G NA + YS +NS ++ + +D + +D ++ ++A Sbjct: 2476 ATDQDSGSNAQIKYSF---PITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAM 2532 Query: 771 S---PPLWNDVRVEILVT 785 PP V V I++T Sbjct: 2533 DQGVPPQRALVYVRIIIT 2550 Score = 227 bits (554), Expect = 1e-58 Identities = 172/587 (29%), Positives = 276/587 (47%), Gaps = 34/587 (5%) Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +P ++ +G + T LDRE + Y L T + PP+S T F Sbjct: 182 IPADLEYNAGVITTKTVLDREKVSAYNL--TIVEFSTPPKSYTV--LVYVQDLNDNSPSF 237 Query: 367 MPG-QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG------ 419 + G ++ + E++ + +D ++ Y I GN F + S+ Sbjct: 238 VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLY 297 Query: 420 RGLITVAQPLDFKQER--RYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYT 475 L+ A + +ER YVL +SA+D G ++ ++++IT D N+ P F N Y+ Sbjct: 298 ADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYS 357 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 ++ E+ +GT++L VSA+D D+G NA+I YS+ + +A+ F I+P TG I Sbjct: 358 GTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAI------FGIHPTTGVIVN 411 Query: 536 NKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA----NI 590 N LD E YL+ V A D G LS + V I V+DVNDN PV YT + Sbjct: 412 NVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVS-YTLGGSYQV 470 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRES 649 E+A +GT V++V +DAD G NG ++ L+ D F + +I ++LDRE+ Sbjct: 471 TENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRET 530 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 LKAV ID G PP+++ I + D+ND P F+ + EN+ + T + + Sbjct: 531 HDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIV 590 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR 768 A D D G N+ + Y+I +S S+ + T DLD E P+ +++ Sbjct: 591 NAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVH 650 Query: 769 -AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK- 826 SPPL ++ V + +TD NDN P + +++ P ++ A D D+ + Sbjct: 651 DRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENS 710 Query: 827 -LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + Y IL+ N L+ G +T S L+ V T +V+ TDG Sbjct: 711 LILYSILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDG 755 Score = 134 bits (324), Expect = 1e-30 Identities = 94/289 (32%), Positives = 143/289 (49%), Gaps = 27/289 (9%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S P + INV D ND PVF Y A EG GT V+ + A D+D G N V + Sbjct: 2637 SKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFA 2696 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I+ + +D + F ID ++G + T+ +LD E + + V V+ATD Sbjct: 2697 IQ-------SGDD------------KGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATD 2737 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDAD 180 + SP + + ++ + ++D NDN P F V V E++ + N + +I ATD D Sbjct: 2738 EGSP---PMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPL--NSRLYEINATDRD 2792 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQDGGSPSRS 238 GAN+ + + +IGG Q F ID SG ++ T DYE V Y L I+A D G+P S Sbjct: 2793 SGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLS 2852 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287 + +++N+ D ++ P F ++ V N IG + +V A D D G Sbjct: 2853 SNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSG 2901 >SB_25361| Best HMM Match : Cadherin (HMM E-Value=0) Length = 4833 Score = 384 bits (945), Expect = e-106 Identities = 260/766 (33%), Positives = 380/766 (49%), Gaps = 55/766 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+SP F Y + E A+ G ++ T+ A+D DIG+NA + Y+I + Sbjct: 1666 VTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSI-------V 1718 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +PE A F ++ +G + LDRE V Y + V ATD ++ Sbjct: 1719 SPEKAT-------------FSMNPVTGEITVGQRLDREGVEHYLLNVTATDNGRLNTN-- 1763 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++ +++N++D NDN PQF Y + E P++ +KA D D G+N ++Y+ Sbjct: 1764 DASVDVYINVLDVNDNAPQFEAAVYHGEISESADKL-TPIVT-VKAIDKDSGSNGIVKYS 1821 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SPSRSNTTQLLINIRD 249 +I GN F+I +G + + LD E+ +Y L +RA D S T+++IN+ D Sbjct: 1822 LISGNDGDAFTILG-NGTIVNAEVLDREKKSTYNLEVRAVDQATSGGLEGVTRVVINVTD 1880 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VND P F TS VSEN +G ++ V A DADEG N ++ Y++ ++ P Sbjct: 1881 VNDQPPEF-TSASVAHVSENSRVGDVVLTVIAVDADEGSNGDVVYSLGL-----DIGAPF 1934 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ++ + G + SG +DRE +A Y + VTATD G PP SA+ F+ Sbjct: 1935 SLGSKDGVLRVSGSMDREKKANYSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFLSH 1994 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 V + E+ PGT ++TL A D D + + Y GN+ F+I S GR + A+ Sbjct: 1995 IGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGR--LRTAR 2052 Query: 428 PLDFKQERRYVLTVSATDSG-GRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + R+ L V A D G R D+ V + + D N+ PVF + Y A V E + Sbjct: 2053 NLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VE 2111 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + ++ V A D D+G + +TY ++ FVIN TG I LDRET S Sbjct: 2112 SNIVTVVAEDRDIGSDGSVTYCITQ-------GREGGLFVINENTGTIGITAKLDRETKS 2164 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L V A DGG P+LS DV ++V+D ND+ PVF T + ED GT+V +V A Sbjct: 2165 KYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSA 2224 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D DVG N + Y L F ID +GVI T + LDRE H L+ +A D G P Sbjct: 2225 VDGDVGSNADVTYSL---KYSFSRFSIDSKTGVITTVRPLDREIAGQHKLEVLASDAGKP 2281 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P + + I + D ND P F+ IS+++P+GT + + A D D G NA YS Sbjct: 2282 PLQGKLDLDIIVGDKNDHDPEFQQSQFQATISQSAPVGTIVFVLSARDEDTGENAESDYS 2341 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 I G+D++ FSL R G V V S +Y L I+AA+ Sbjct: 2342 ITSGNDASVFSLNARSG------VISVSRTVPSSPAQYSLKIKAAN 2381 Score = 358 bits (880), Expect = 4e-98 Identities = 310/1112 (27%), Positives = 492/1112 (44%), Gaps = 88/1112 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ P F + Y + E ++ G TV+ + A D D G N E+ Y L + Sbjct: 2694 KVTVTDINDNPPKFLLLPYVTQLPEDSAVGVTVMNVTAVDADEGTNVELNYEFLLSPYGS 2753 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 DA R+ A ++L + Y + V+A + P Sbjct: 2754 FLAVDARTGMITL-----------NRAIAFKPFSALPNPNI--YNLTVRARNIYPP---H 2797 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIR 188 + A I + ++D ND+ P F + Y + +D I +++A D D G N+ +R Sbjct: 2798 YKADAAIQIEVLDTNDHAPVFVKSVYLLFAVQDAG--SGVSIGRVEAVDKFDYGPNALVR 2855 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y I GN +F + +G+V + +L + ++Y + +RA D G P S+T + + + Sbjct: 2856 YEAISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVT 2915 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 + N + P F +++Q S +E++ +G +++ V A D D G N E++Y + GN Sbjct: 2916 ERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDII----AGNSQEY 2971 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 I +G +Y S LD E Q Y L V+ATDGG P+++ AT F P Sbjct: 2972 FGIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSP 3031 Query: 369 GQYEVELAEDEPPGTPVV-TLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425 +Y ELAE+ P + VV ++ ATD DE + + Y I GG+ + +F I + G TV Sbjct: 3032 IEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKDKFVIDERTGEIRATV 3091 Query: 426 AQPLDFKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 DF+ L ++A D G A V I IT N + PVF + +TA+V E Sbjct: 3092 E--FDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAE 3149 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +APIG +VL VSATD D G + + Y L + + Q F ++ TG ++ + LD Sbjct: 3150 NAPIGHSVLRVSATDKDKGPDGVVLYHLLG-------SDNQQGFDLDSNTGTLSVSGDLD 3202 Query: 541 RETMSGYLLTVTARD----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 E L V A++ PS + ++V D ND P F + +Y+A++ E + + Sbjct: 3203 NERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDAND-PPRFLKSVYSAHVTEGSRI 3261 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G V+ V A D D + I Y + + +FV+D +G +RT LDRE++A + L Sbjct: 3262 GHVVTNVTAVDDDSDIRS-IRYGISAGNTGN-AFVMDAVTGFVRTAAELDREAIAEYRLT 3319 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D GTPP + + + ++DIND+PP ++EN P GT + + A DPD Sbjct: 3320 VTATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDL 3379 Query: 717 GPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 PN YSI G D SF L G + T+ LD E + Y + I+ Sbjct: 3380 NPNRGPFKYSI-SGSDYGSFRLNVSSG----VVSTVKSLDREK-QDAYNISIKVTDARGL 3433 Query: 776 NDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 + V I V D NDN P + + ++ F G V D D+ D + +L+ Sbjct: 3434 SAVNFCMIHVEDQNDNRPKATSRDVYVHTFEGKFLGGVVADVRPDDPDIDDPMTCALLNP 3493 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894 N + + G+ LS L + + V+ +DG+ + ++ L TE L Sbjct: 3494 PQNN--IFSFPRGNCELS-SLAYSQDARFDLSVNGSDGLGAVTYLITLRFLGYTETTLQQ 3550 Query: 895 SITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSAR 954 + VRL + FL+ F + A +P + I SV + +++V S R Sbjct: 3551 GVVVRLRNTNTRDFLANSYHKFTSAVNATLPSGYSS-QIMSVDSSGE---GLVDVLASVR 3606 Query: 955 RPDAEVGVAGDPSPHYSPTHLRERVYLH-RTTLARLATVQVLPFDDNIC-VHEPCLNFEE 1012 + + +R+RV H + L + + + D N C CLN E Sbjct: 3607 QGGTLM--------------IRDRVSGHLKDKLVSSSALDIAAVDYNPCTTGNQCLNGGE 3652 Query: 1013 CLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI 1072 C + ++ V+S V+ TC C GFTG CE + D + + Sbjct: 3653 CSSAIQASRRGHVVSSTPVVMVTAGYTWKITCSCKPGFTGSQCEESVN------DCNPNP 3706 Query: 1073 CRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 CR+ C G CS YT +CE Sbjct: 3707 CRNEGTC-TDNNGSF---KCSCIPGYTGRLCE 3734 Score = 348 bits (855), Expect = 4e-95 Identities = 260/859 (30%), Positives = 407/859 (47%), Gaps = 71/859 (8%) Query: 4 PFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 P +I V+ D NDH PVF + E AS GT ++TL+A D D G NAE+ Y Sbjct: 1970 PLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYA 2029 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 VT ++ N F I+ +G L T +LDRE R+T+ V A D Sbjct: 2030 --FVTGNSNNS-----------------FTINSITGRLRTARNLDRETTPRFTLEVLAYD 2070 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 P R S + V + D NDN P F+ Y V E + V N I + A D D+ Sbjct: 2071 LGVP---RKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VESN--IVTVVAEDRDI 2124 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 G++ ++ Y I G F I+ +G + + LD E Y L ++A DGGSP+ S+ Sbjct: 2125 GSDGSVTYCITQGREGGLFVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEA 2184 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 +++N+ D ND+AP F + V E+ G ++++V A D D G NA++TY++ Y Sbjct: 2185 DVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSL---KY 2241 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + + +ID ++G + T LDRE +++L V A+D G PP Sbjct: 2242 SFS---RFSIDSKTGVITTVRPLDREIAGQHKLEVLASDAGKPPLQGKLDLDIIVGDKND 2298 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F Q++ +++ P GT V L+A D D E+ Y IT GN FS+ +++ Sbjct: 2299 HDPEFQQSQFQATISQSAPVGTIVFVLSARDEDTGENAESDYSITSGNDASVFSLNARS- 2357 Query: 420 RGLITVAQPLDFKQERRYVLTVSAT--DSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477 G+I+V++ + +Y L + A ++ GR+D+A +QI ++ A P F + + S Sbjct: 2358 -GVISVSRTVP-SSPAQYSLKIKAANRNAPGRTDSATLQITVSSA--VFPRFLHPDQSIS 2413 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E +G +L V+AT T+ + A +H F ++ G + Sbjct: 2414 ISELTRVGMEILTVNAT-------GHTTFDI-------AGGNHGDAFDVDAVQGVVKVKT 2459 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD E Y L + A DG VP V I++ D NDN PVF Q++YTA++ E G Sbjct: 2460 PLDYERYPNYTLIIGAYDGSVPPHVGYARVVITLQDENDNVPVFSQRVYTAHVPEGKSAG 2519 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 SV V A+D D G+N + Y L G F + +G++ T+ LDRE V ++ LK Sbjct: 2520 VSVLTVLASDEDSGVNAEVEYHL----VGSGPFQVSRTTGLVTTSDVLDRELVGSYTLKV 2575 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A + G +S IVH+ + DIND+PP + LT +SE + G + ++ D DE Sbjct: 2576 RAENPGNRSMASEAIVHVTVTDINDTPPTLQQP-LTASVSEQAQAGDLVLQLHGDDKDEP 2634 Query: 718 PNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLW 775 N+ +HY + G+ F++ G+ +T+V +LD E+ + Y L + Sbjct: 2635 VNSPLHYGFLPNGNPGGVFAIGALSGN-----ITLVKNLDRET-KSLYSLEVFVNDSLHV 2688 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833 V++ VTD+NDN P + +D V A DAD +L Y L Sbjct: 2689 TQATVKVTVTDINDNPPKFLLLPYVTQLPEDSAVGVTVMNVTAVDADEGTNVELNYEFLL 2748 Query: 834 GNNANLILLNETTGSMTLS 852 + + ++ TG +TL+ Sbjct: 2749 SPYGSFLAVDARTGMITLN 2767 Score = 344 bits (846), Expect = 5e-94 Identities = 270/877 (30%), Positives = 413/877 (47%), Gaps = 69/877 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VL+ D+ PVF + Y +V E GT V + AT +D KN + Y I V+ D Sbjct: 619 VTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKD--KNGSISYAI--VSGDPT 674 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +F +D G + +DRE+ A+Y + V A + V L Sbjct: 675 N-----------------LFLVDSTGGIIKINGDMDREEKAQYLLAVIA--RVGTVKP-L 714 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ AT+++ ++D NDN PQFS T +V VD D + V+ A D D G N +RY Sbjct: 715 SAQATVNIEVLDRNDNAPQFS--TSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQ 772 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + N + I+S SG + L + L Y + + A D GSP + +T + I + + Sbjct: 773 LT-SNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL-SI 830 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N + P+F S + V + P+ Y V A D D G N +L Y++ GN + Sbjct: 831 N-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ----GNEEGLFG 885 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I P G +Y L + + Y L+V ATDGG P SA+ F+ Sbjct: 886 IFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNT 944 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + +AE+ PGT V TL A D + ++ F++ ++G+ IT LD Sbjct: 945 FRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQ--ITTRVRLD 1002 Query: 431 FKQ------ERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 ++ Y++ A D+ + D A+V + +TD N+ APVF A Y +V E + Sbjct: 1003 REELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELS 1062 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G+ V + A D+D G NA+ YSL S + +F IN TG + +K LDRE Sbjct: 1063 LPGSPVFRIKAMDADKGDNAKFFYSLVSGTGMD-------KFFINSSTGELHLSKTLDRE 1115 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T S Y L V A D +L T +EI+V D ND PVF + YT NI EDAL+G+ V Sbjct: 1116 TTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVIN 1175 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + A+D D+G NG I Y + F ++ A+G + K+LD E+ ++L A D Sbjct: 1176 LNASDKDIGQNGLIKYSIS-NGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDH 1234 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G P SSTV V + + D+ND+ P+F + +T + EN G +G A D D G NA + Sbjct: 1235 GLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHI 1294 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE---SPRKKYELVIRA---ASPPLWN 776 +S+ S +FS+ S E+ T+ +D E + R ++LV+ A SP L Sbjct: 1295 AFSMYSQTPSKTFSV----NSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLST 1350 Query: 777 DVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835 + + VTD NDN+P + + + + D + K+ Y I+SGN Sbjct: 1351 RKSITVQVTDENDNSPGFVSPPAAAAGSSLNVMTI----TAEDPDRNSNGKVTYSIISGN 1406 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 N L+ +TG + + Q+ N P + + + +DG Sbjct: 1407 N-GYFNLHPSTGQLQMIHQIPDN-PTIYQLTIQASDG 1441 Score = 340 bits (835), Expect = 1e-92 Identities = 272/877 (31%), Positives = 407/877 (46%), Gaps = 68/877 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++PVF Y +V E + G+ V +KA D D G NA+ Y++ T Sbjct: 1037 VTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADKGDNAKFFYSLVSGTG--- 1093 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D F I+ +G L +LDRE + Y ++VKATD ++ L Sbjct: 1094 ----------------MDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNA---NL 1134 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 STA I + + D ND P F E YTV++ ED + ++ + A+D D+G N I+Y+ Sbjct: 1135 YSTAKIEITVGDSNDQRPVFPESDYTVNITEDALI--GSLVINLNASDKDIGQNGLIKYS 1192 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN F ++S +G + + K+LD+E + Y L I AQD G S+T + +N+ DV Sbjct: 1193 ISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDV 1252 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP F T +V ENV G+ + R A D D G NA + ++M Y+ + Sbjct: 1253 NDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSM----YSQTPSKTFS 1308 Query: 311 IDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++ + + T +D ET + +QL+V ATD G P S + F Sbjct: 1309 VNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGF 1368 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLIT 424 + A V+T+TA D D ++ ++ Y I GN G F++ G+ L Sbjct: 1369 VSPP-----AAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGN-NGYFNLHPSTGQ-LQM 1421 Query: 425 VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + Q D Y LT+ A+D G R +V + P F +A Y SV E+ Sbjct: 1422 IHQIPD--NPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENK 1479 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 GT+V+ V A +N I Y L+S+ S F + TG + T + +DRE Sbjct: 1480 VAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGG-------FEVVKSTGVVKTTRGIDRE 1532 Query: 543 TM-SGYLLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 M + + L V A D PS + + V I+V DVNDN PVF +T +I E+ GT+V Sbjct: 1533 GMGASFNLVVYAVDKQGPSARTSSATVTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTV 1592 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V ATD D G N ++ Y F ID +SG I T DRE+ + + A Sbjct: 1593 ITVTATDPDAGDNAKVSY-ATYGGSHGNKFAIDASSGRIYTTGTFDRETKDDYSINVTAS 1651 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G P +SST +V + + D ND+ P F + F I+E++ +G +IG + A D D G NA Sbjct: 1652 DHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENA 1711 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN---- 776 + YSI + + +FS+ G E+ LD E + Y L + A N Sbjct: 1712 RLTYSIVSPEKA-TFSMNPVTG----EITVGQRLDREGV-EHYLLNVTATDNGRLNTNDA 1765 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSG 834 V V I V DVNDNAP + + + P V A D D ++Y ++SG Sbjct: 1766 SVDVYINVLDVNDNAPQFEAAVYHGEISESADKLTPIVTVKAIDKDSGSNGIVKYSLISG 1825 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 N+ + + G++ + L+ +EV D Sbjct: 1826 NDGDAFTI-LGNGTIVNAEVLDREKKSTYNLEVRAVD 1861 Score = 338 bits (832), Expect = 3e-92 Identities = 265/888 (29%), Positives = 425/888 (47%), Gaps = 70/888 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INV D ND P F A V E + G VLT+ A D D G N +V Y++ L D Sbjct: 1876 INVTDVNDQPPEFTSASV-AHVSENSRVGDVVLTVIAVDADEGSNGDVVYSLGL---DIG 1931 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F + + G L S+DREK A Y++ V ATD +P L Sbjct: 1932 AP-----------------FSLGSKDGVLRVSGSMDREKKANYSIRVTATDLGTPP---L 1971 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S++ I V + D ND+ P F TV +DE+ S I ++A D D G N+ IRYA Sbjct: 1972 SASMEITVIVDDYNDHRPVFLSHIGTVFIDENAS--PGTEIITLQAVDGDSGVNAEIRYA 2029 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + GN+ F+I+S++G + + LD E + L + A D G P + + T + + +RDV Sbjct: 2030 FVTGNSNNSFTINSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDV 2089 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F S + VSE V + +IV V A D D G + +TY +T G Sbjct: 2090 NDNQPVFTMSEYAAEVSEGV-VESNIVTVVAEDRDIGSDGSVTYCITQ----GREGGLFV 2144 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G + + +LDRET++KY L V ATDGG P S+ A F P Sbjct: 2145 INENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPAT 2204 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 V++ ED GT V+ ++A D D + + + RFSI S+ G +IT +PLD Sbjct: 2205 LTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSLKYSFSRFSIDSKTG--VITTVRPLD 2262 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTV 488 + ++ L V A+D+G + ++I D N++ P F+ + + A++ + AP+GT V Sbjct: 2263 REIAGQHKLEVLASDAGKPPLQGKLDLDIIVGDKNDHDPEFQQSQFQATISQSAPVGTIV 2322 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 V+SA D D G NA+ YS++S N+A F +N ++G I+ ++ + + + Y Sbjct: 2323 FVLSARDEDTGENAESDYSITS--GNDASV-----FSLNARSGVISVSRTVP-SSPAQYS 2374 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L + A + P +D+ ++I+V + VF + L+ + ++ + +++VG Sbjct: 2375 LKIKAANRNAPGRTDSATLQITV-----SSAVFPRFLHP----DQSISISELTRVGMEIL 2425 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 V G +++ + + +F +D GV++ LD E + L A DG PP Sbjct: 2426 TVNATGHTTFDIAGGNHGD-AFDVDAVQGVVKVKTPLDYERYPNYTLIIGAYDGSVPPHV 2484 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 V I ++D ND+ PVF T ++ E G ++ + A D D G NA V Y + G Sbjct: 2485 GYARVVITLQDENDNVPVFSQRVYTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEYHLVG 2544 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVT 785 S F + G LVT D+ Y L +RA +P + ++ V + VT Sbjct: 2545 ---SGPFQVSRTTG-----LVTTSDVLDRELVGSYTLKVRAENPGNRSMASEAIVHVTVT 2596 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTDKLQYRIL-SGNNANLIL 841 D+ND P ++ Q + + + G ++ D D V L Y L +GN + Sbjct: 2597 DINDTPPTLQ--QPLTASVSEQAQAGDLVLQLHGDDKDEPVNSPLHYGFLPNGNPGGVFA 2654 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 + +G++TL L+ L ++EV V D ++ +A ++++V I + Sbjct: 2655 IGALSGNITLVKNLDRETKSLYSLEVFVNDSLHVTQATVKVTVTDIND 2702 Score = 334 bits (821), Expect = 6e-91 Identities = 261/887 (29%), Positives = 419/887 (47%), Gaps = 70/887 (7%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 SVP I+ Q D NDH +F + +V E +S GT V TL A D + ++ Y+ Sbjct: 923 SVPVTIYIQ----DSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYS 978 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVK 118 L+++++ F +D RSG + TR LDRE++ + T V + Sbjct: 979 --LISSESH-------------------FAVDVRSGQITTRVRLDREELIKNTGSNVYIM 1017 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 + + A + V + D NDN P FS Y ++V E +S+ +PV +IKA D Sbjct: 1018 QAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSE-LSLPGSPVF-RIKAMD 1075 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 AD G N+ Y+++ G +F I+S +G++ L KTLD E SY LV++A D + + Sbjct: 1076 ADKGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLY 1135 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 +T ++ I + D ND P F S + +++E+ IG ++ + A D D G N + Y++++ Sbjct: 1136 STAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISN 1195 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 GN+ ++ +G + + LD ET Y+L +TA D G P S+T Sbjct: 1196 ----GNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLD 1251 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS 416 F + + E+ G PV TA+D D H + + FS+ S Sbjct: 1252 VNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNS 1311 Query: 417 QNGRGLITVAQPLDFKQERR--YVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA 472 A L+ R + L V ATD G S + + +TD N+ +P F + Sbjct: 1312 ATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSP 1371 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 P A A V+ ++A D D N ++TYS+ ++ ++ F ++P TG Sbjct: 1372 PAAA-----AGSSLNVMTITAEDPDRNSNGKVTYSI--------ISGNNGYFNLHPSTGQ 1418 Query: 533 I-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + +++ D T+ Y LT+ A DGG PS T V + P F Y ++ Sbjct: 1419 LQMIHQIPDNPTI--YQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVT 1476 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV- 650 E+ + GTSV V A LNG I Y L D +G F + ++GV++T + +DRE + Sbjct: 1477 ENKVAGTSVVTVLAAYPQSSLNGNIEYYL-TSDSSKGGFEVVKSTGVVKTTRGIDREGMG 1535 Query: 651 ATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 A+ +L A+D G ++S+ V I ++D+ND+ PVF SD T I+EN GTT+ + Sbjct: 1536 ASFNLVVYAVDKQGPSARTSSATVTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITV 1595 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A DPD G NA V Y+ GG N F+++ G + T D E+ + Y + + A Sbjct: 1596 TATDPDAGDNAKVSYATYGGSHGNKFAIDASSG----RIYTTGTFDRET-KDDYSINVTA 1650 Query: 770 A---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD- 825 + +P + V + V D NDN+P +F+ +D G V A DAD+ + Sbjct: 1651 SDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGEN 1710 Query: 826 -KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +L Y I+S A +N TG +T+ +L+ + + V+ TD Sbjct: 1711 ARLTYSIVSPEKAT-FSMNPVTGEITVGQRLDREGVEHYLLNVTATD 1756 Score = 332 bits (816), Expect = 2e-90 Identities = 274/875 (31%), Positives = 411/875 (46%), Gaps = 68/875 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+SP F A A S V+T+ A D D N +V Y+I + Sbjct: 1356 VQVTDENDNSPGFVSPPAAA-----AGSSLNVMTITAEDPDRNSNGKVTYSI-------I 1403 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + +Q + +I D + Y + ++A+D P Sbjct: 1404 SGNNGYFNLHPSTGQLQMIHQIP------------DNPTI--YQLTIQASDGGQPSRQTQ 1449 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + I P FS Y SV E+ V V+ + A N I Y Sbjct: 1450 TVVSVFKEGPIGGG---PTFSSADYQGSVTEN-KVAGTSVVTVLAAYPQS-SLNGNIEYY 1504 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPS-RSNTTQLLINIR 248 + +++ F + +G V + +D E + S+ LV+ A D PS R+++ + I ++ Sbjct: 1505 LTSDSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQ 1564 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDNAP F + F S++ENV G +++ V A D D G NA+++Y Y G+ Sbjct: 1565 DVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSYAT----YGGSHGNK 1620 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID SG +YT+G DRET+ Y + VTA+D G+P +S+T F Sbjct: 1621 FAIDASSGRIYTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPA 1680 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y ++AED G + T++A+DAD E+ RL Y I + FS+ G ITV Sbjct: 1681 LHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVSPE-KATFSMNPVTGE--ITVG 1737 Query: 427 QPLDFKQERRYVLTVSATDSG--GRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAP 483 Q LD + Y+L V+ATD+G +D ++ V IN+ D N+ AP FE A Y + E A Sbjct: 1738 QRLDREGVEHYLLNVTATDNGRLNTNDASVDVYINVLDVNDNAPQFEAAVYHGEISESAD 1797 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 T ++ V A D D G N + YSL S +A F I G I ++LDRE Sbjct: 1798 KLTPIVTVKAIDKDSGSNGIVKYSLISGNDGDA-------FTILGN-GTIVNAEVLDREK 1849 Query: 544 MSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y L V A D L T V I+V DVND P F A++ E++ VG V Sbjct: 1850 KSTYNLEVRAVDQATSGGLEGVTRVVINVTDVNDQPPEFTSAS-VAHVSENSRVGDVVLT 1908 Query: 603 VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A DAD G NG + Y L + G+ F + GV+R + ++DRE A + ++ A D Sbjct: 1909 VIAVDADEGSNGDVVYSLG---LDIGAPFSLGSKDGVLRVSGSMDREKKANYSIRVTATD 1965 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 GTPP S+++ + + ++D ND PVF S T +I EN+ GT I ++A D D G NA Sbjct: 1966 LGTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAE 2025 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDV-R 779 + Y+ G+ +NSF++ + G L T +LD E+ PR E++ P + V Sbjct: 2026 IRYAFVTGNSNNSFTINSITG----RLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTN 2081 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNA 837 V +++ DVNDN PV + + V A D D+ + Y I G Sbjct: 2082 VTVVLRDVNDNQPVFTMSEYAAE-VSEGVVESNIVTVVAEDRDIGSDGSVTYCITQGREG 2140 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 L ++NE TG++ ++ +L+ T+ V TDG Sbjct: 2141 GLFVINENTGTIGITAKLDRETKSKYTLRVQATDG 2175 Score = 318 bits (780), Expect = 5e-86 Identities = 265/885 (29%), Positives = 400/885 (45%), Gaps = 75/885 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ PVF + Y A V EG S+G +VLT+ A+D+D G NAEVEY LV + Sbjct: 2491 ITLQDENDNVPVFSQRVYTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEY--HLVGSGP- 2547 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F++ +G + T LDRE V YT+ V+A + P + + Sbjct: 2548 -------------------FQVSRTTGLVTTSDVLDRELVGSYTLKVRAEN---PGNRSM 2585 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S A +HV + D ND P ++ T SV E D ++ ++ D D NS + Y Sbjct: 2586 ASEAIVHVTVTDINDTPPTL-QQPLTASVSEQAQAGD--LVLQLHGDDKDEPVNSPLHYG 2642 Query: 191 II-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + GN F+I +LSG+++LVK LD E Y L + D +++ + + D Sbjct: 2643 FLPNGNPGGVFAIGALSGNITLVKNLDRETKSLYSLEVFVNDSLHVTQATVK---VTVTD 2699 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P+F + + E+ +G +++ V A DADEG N EL Y Y G+ + Sbjct: 2700 INDNPPKFLLLPYVTQLPEDSAVGVTVMNVTAVDADEGTNVELNYEFLLSPY-GSF---L 2755 Query: 310 TIDPRSGWVYTSGQLDRETQAK------YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +D R+G + + + + + Y L V A + P A A Sbjct: 2756 AVDARTGMITLNRAIAFKPFSALPNPNIYNLTVRARNIYPPHYKADAAIQIEVLDTNDHA 2815 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL-HYEITGGNTRGRFSITSQNGR 420 F+ Y + +D G + + A D + N L YE GN GRF + + G Sbjct: 2816 PVFVKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPETGE 2875 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASV 478 LI A L + Y + V A+D G SDTA V + +T+ N + PVF A Y S Sbjct: 2876 VLI--ASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSE 2933 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED +G+ +L V+ATD D G N +I+Y + + S E F I G++ +K Sbjct: 2934 NEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQE-------YFGIGLTNGSLYVSKP 2986 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV-G 597 LD E Y L V+A DGG + V I++ DVNDN PVF Y + E+ Sbjct: 2987 LDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTPRS 3046 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V V ATD D + Y + ++ FVID +G IR D E + L Sbjct: 3047 VVVCSVRATDRDERGQQSVRYSILGGSGKD-KFVIDERTGEIRATVEFDFEVTMSSFLMI 3105 Query: 658 VAIDGGTPPQSST---VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 A D G PQ + VHI I +N+ PVF T ++EN+PIG ++ + A D Sbjct: 3106 AAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDK 3165 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI------R 768 D+GP+ VV Y + G D+ F L++ G+ L DLD E VI Sbjct: 3166 DKGPDGVVLYHLLGSDNQQGFDLDSNTGT----LSVSGDLDNERAGIVTLRVIAKNLFQN 3221 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK- 826 + +P + + VTD ND +K + + + +G V A D D + Sbjct: 3222 SVTPSSVAHATIVVTVTDANDPPRFLK--SVYSAHVTEGSRIGHVVTNVTAVDDDSDIRS 3279 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++Y I +GN N +++ TG + + +L+ + V+ TD Sbjct: 3280 IRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATD 3324 Score = 295 bits (723), Expect = 4e-79 Identities = 242/877 (27%), Positives = 396/877 (45%), Gaps = 74/877 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH P F+ Q++A++ + A GT V L A D+D G+NAE +Y+I Sbjct: 2291 IIVGDKNDHDPEFQQSQFQATISQSAPVGTIVFVLSARDEDTGENAESDYSIT------- 2343 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + DA VF ++ RSG + ++ A+Y++ +KA ++ +P Sbjct: 2344 SGNDAS------------VFSLNARSGVISVSRTVPSSP-AQYSLKIKAANRNAPGR--- 2387 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + +AT+ + + + +P+F ++S+ E + ++ V A + Sbjct: 2388 TDSATLQITV--SSAVFPRFLHPDQSISISE---------LTRVGMEILTVNATGHTTFD 2436 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GGN F +D++ G V + LDYE+ +Y L+I A DG P +++I ++D Sbjct: 2437 IAGGNHGDAFDVDAVQGVVKVKTPLDYERYPNYTLIIGAYDGSVPPHVGYARVVITLQDE 2496 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F ++ V E G S++ V A D D GVNAE+ Y + P Sbjct: 2497 NDNVPVFSQRVYTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEYHLVGSG-------PFQ 2549 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 + +G V TS LDRE Y L V A + G+ ++ A + Sbjct: 2550 VSRTTGLVTTSDVLDRELVGSYTLKVRAENPGNRSMASEAIVHVTVTDINDTPPT-LQQP 2608 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYE-ITGGNTRGRFSITSQNGRGLITVAQ 427 ++E G V+ L D DE ++ LHY + GN G F+I + +G IT+ + Sbjct: 2609 LTASVSEQAQAGDLVLQLHGDDKDEPVNSPLHYGFLPNGNPGGVFAIGALSGN--ITLVK 2666 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 LD + + Y L V DS A V++ +TD N+ P F PY + ED+ +G T Sbjct: 2667 NLDRETKSLYSLEVFVNDS-LHVTQATVKVTVTDINDNPPKFLLLPYVTQLPEDSAVGVT 2725 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG- 546 V+ V+A D+D G N ++ Y ++ + ++ +TG IT N+ + + S Sbjct: 2726 VMNVTAVDADEGTNVELNYEF-------LLSPYGSFLAVDARTGMITLNRAIAFKPFSAL 2778 Query: 547 -----YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 Y LTV AR+ P ++I V+D ND+ PVF + +Y ++DA G S+ Sbjct: 2779 PNPNIYNLTVRARNIYPPHYKADAAIQIEVLDTNDHAPVFVKSVYLLFAVQDAGSGVSIG 2838 Query: 602 QVGATDA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +V A D D G N + YE G F + P +G + +L + T+ ++ A Sbjct: 2839 RVEAVDKFDYGPNALVRYEA-ISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRAS 2897 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G P S T V++++ + N PPVF +E+ +G+ + + A D D G N Sbjct: 2898 DMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNG 2957 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777 + Y I G+ F + GS L LDYE ++ Y L + A P + Sbjct: 2958 EISYDIIAGNSQEYFGIGLTNGS----LYVSKPLDYEH-QENYSLNVSATDGGKEPKTSY 3012 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSG 834 V I + DVNDN PV + ++ P V A D D ++Y IL G Sbjct: 3013 ATVRITLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGG 3072 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + +++E TG + + + + V + + ++ D Sbjct: 3073 SGKDKFVIDERTGEIRATVEFDFEVTMSSFLMIAAKD 3109 Score = 285 bits (700), Expect = 3e-76 Identities = 251/887 (28%), Positives = 390/887 (43%), Gaps = 85/887 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD NDH+PVF V+E SGTTV+ + A D D+G NA+V Y+++ + Sbjct: 2188 VNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSLKYSFSR-- 2245 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ID ++G + T LDRE ++ + V A+D P L Sbjct: 2246 -------------------FSIDSKTGVITTVRPLDREIAGQHKLEVLASDAGKPP---L 2283 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + + D ND+ P+F + + ++ + V ++ + A D D G N+ Y+ Sbjct: 2284 QGKLDLDIIVGDKNDHDPEFQQSQFQATISQSAPV--GTIVFVLSARDEDTGENAESDYS 2341 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN FS+++ SG +S+ +T+ + Y L I+A + +P R+++ L I + Sbjct: 2342 ITSGNDASVFSLNARSGVISVSRTVPSSPAQ-YSLKIKAANRNAPGRTDSATLQITVSSA 2400 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 PRF S+SE +G I+ V A T+ + GN Sbjct: 2401 V--FPRFLHPDQSISISELTRVGMEILTVNA-------TGHTTFDIAG----GNHGDAFD 2447 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +D G V LD E Y L++ A DG PP A F Sbjct: 2448 VDAVQGVVKVKTPLDYERYPNYTLIIGAYDGSVPPHVGYARVVITLQDENDNVPVFSQRV 2507 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y + E + G V+T+ A+D D + + Y + G G F ++ G L+T + Sbjct: 2508 YTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEYHLVGS---GPFQVSRTTG--LVTTSDV 2562 Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y L V A + G RS A+V + +TD N+ P + P TASV E A G Sbjct: 2563 LDRELVGSYTLKVRAENPGNRSMASEAIVHVTVTDINDTPPTLQQ-PLTASVSEQAQAGD 2621 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 VL + D D +N+ + Y + V F I +G IT K LDRET S Sbjct: 2622 LVLQLHGDDKDEPVNSPLHYGFLPNGNPGGV------FAIGALSGNITLVKNLDRETKSL 2675 Query: 547 YLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L V D SL T V+++V D+NDN P F Y + ED+ VG +V V A Sbjct: 2676 YSLEVFVND----SLHVTQATVKVTVTDINDNPPKFLLLPYVTQLPEDSAVGVTVMNVTA 2731 Query: 606 TDADVGLNGRIHYE--LDPKDREEGSFV-IDPASGVIRTNKALDRESVAT------HDLK 656 DAD G N ++YE L P GSF+ +D +G+I N+A+ + + ++L Sbjct: 2732 VDADEGTNVELNYEFLLSPY----GSFLAVDARTGMITLNRAIAFKPFSALPNPNIYNLT 2787 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP-D 715 A + P + + I++ D ND PVF + +++ G +IG + A D D Sbjct: 2788 VRARNIYPPHYKADAAIQIEVLDTNDHAPVFVKSVYLLFAVQDAGSGVSIGRVEAVDKFD 2847 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772 GPNA+V Y G+ + F + G V + + K Y + +RA+ P Sbjct: 2848 YGPNALVRYEAISGNGTGRFRVAPETGE-----VLIASSLRDDVNKTYYIRVRASDMGQP 2902 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYR 830 + + V + VT+ N + PV + +D V A D D ++ Y Sbjct: 2903 KMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYD 2962 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877 I++GN+ + T GS+ +S L+ + ++ VS TDG E K Sbjct: 2963 IIAGNSQEYFGIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPK 3009 Score = 279 bits (684), Expect = 2e-74 Identities = 238/839 (28%), Positives = 381/839 (45%), Gaps = 58/839 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G + T ASLD E +++++ A D + + + TA ++V +++ DN P Sbjct: 574 FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYA---AKTAVVNVTVLNKADNLPV 630 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F + Y +V E +V ++ ++ AT D N +I YAI+ G+ F +DS G + Sbjct: 631 FLYEMYNFTVYE--NVPKGTLVGRVYATTKD--KNGSISYAIVSGDPTNLFLVDSTGGII 686 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + +D E+ Y L + A+ G S + I + D NDNAP+F TS + Sbjct: 687 KINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGT 746 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 +G + A D D G N + Y + T N + + I+ SG + + +L + Sbjct: 747 WLVGQVVYNAAAVDLDAGKNGLVRYQL-----TSNAEGLLWINSTSGVIKLARKLTDGDE 801 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 +Y + V A+D G PP+ +T T F Y + +P + Sbjct: 802 TQYTVQVLASDSGSPPQHSTMT--IHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVV 859 Query: 390 ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 A D D ++ +L Y I GN G F I G + + + L + Y L V ATD G Sbjct: 860 AVDQDSGKNGQLFYSIPQGNEEGLFGIFP---GGKLYIRKSLLQALKGSYDLIVRATDGG 916 Query: 448 GRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 S +A V + I D+N++ +F N + +V E++ GT V + A D I Sbjct: 917 VPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIV 976 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM------SGYLLTVTARDGGVP 559 YSL IS+E+ F ++ ++G ITT LDRE + + Y++ A Sbjct: 977 YSL---ISSES------HFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTT 1027 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 D V ++V D+NDN PVF + +Y + E +L G+ V ++ A DAD G N + Y Sbjct: 1028 IKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADKGDNAKFFYS 1087 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 L F I+ ++G + +K LDRE+ ++++L A D ST + I + D Sbjct: 1088 L-VSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGD 1146 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739 ND PVF T I+E++ IG+ + + A D D G N ++ YSI G+ + F +E+ Sbjct: 1147 SNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVES 1206 Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVTDVNDNAPVMKD 796 G L+ LD+E+ + YEL I A PL + V V + V DVNDNAP+ Sbjct: 1207 ATG----RLIVAKSLDFET-TQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPT 1261 Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 + ++ P GR A D D + + + S + +N T +T Sbjct: 1262 QPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAA 1321 Query: 855 LNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDM--TAEQFLSP 911 ++ L TM + A Q S +L T + SITV++ D + F+SP Sbjct: 1322 ID-----LETMPAGRDSFQLVVMATDQGSPKLSTRK----SITVQVTDENDNSPGFVSP 1371 Score = 250 bits (613), Expect = 9e-66 Identities = 212/754 (28%), Positives = 338/754 (44%), Gaps = 40/754 (5%) Query: 149 QFSEKTYTVSV-DEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 Q S T T++ D + + D + ++ + GGN FSIDS +G Sbjct: 522 QVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGGNNNGNFSIDSSTG 581 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +S + +LD+E + L+I A+DGG+ + T + + + + DN P F ++ +V Sbjct: 582 VISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVY 641 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 ENVP G + RV A D+ N ++Y + D T N+ L +D G + +G +DRE Sbjct: 642 ENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPT-NLFL---VDSTGGIIKINGDMDRE 695 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 +A+Y L V A G P SA AT F V++ G V Sbjct: 696 EKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYN 755 Query: 388 LTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 A D D ++ + Y++T N G I S + G+I +A+ L E +Y + V A+D Sbjct: 756 AAAVDLDAGKNGLVRYQLT-SNAEGLLWINSTS--GVIKLARKLTDGDETQYTVQVLASD 812 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 SG + + I+IT + N+ P F + Y V P+ V A D D G N Q+ Sbjct: 813 SGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLF 872 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 YS+ NE + F I P G + K L + Y L V A DGGVPS S + Sbjct: 873 YSIPQ--GNE-----EGLFGIFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASV 924 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V I + D ND+ +F + + E++ GT V + A D I Y L Sbjct: 925 PVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSL---IS 981 Query: 626 EEGSFVIDPASGVIRTNKALDRESVA------THDLKAVAIDGGTPPQSSTVIVHIKIED 679 E F +D SG I T LDRE + + ++A A+ T + IV + + D Sbjct: 982 SESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTD 1041 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739 +ND+ PVF +SE S G+ + I+A D D+G NA YS+ G + F + + Sbjct: 1042 LNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADKGDNAKFFYSLVSGTGMDKFFINS 1101 Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKD 796 G EL LD E+ Y LV++ A++ L++ ++EI V D ND PV + Sbjct: 1102 STG----ELHLSKTLDRET-TSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPE 1156 Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQ 854 N +D + A D D+ ++Y I +GN A + + TG + ++ Sbjct: 1157 SDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKS 1216 Query: 855 LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 L+ +L + ++ D G+ + + + ++V ++ Sbjct: 1217 LDFETTQLYELTITAQDHGLIPLSSTVNVTVNVL 1250 Score = 215 bits (524), Expect = 6e-55 Identities = 160/516 (31%), Positives = 256/516 (49%), Gaps = 41/516 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-PVSDRLSSTATIHVNIIDDNDNYP 148 F + +G + T A +DRE + ++ ++ + ++ P+S + V + D NDN P Sbjct: 72 FGFNSNTGVISTTARIDRETTTQISLQLRTLNPSNQPIS--------VQVQVDDINDNEP 123 Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS- 206 +F YT+ + E + V T NP+ ATD D G N + Y I G+ FS+ + + Sbjct: 124 RFPTLYYTLRIRESMDVNTTNPINT---ATDPDAGNNGTVDYTIASGDNTATFSLGTTAC 180 Query: 207 --GDVSLV---KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 G V K LD E Y+L I A D G+P+ + I I D ND+AP F + Sbjct: 181 PTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNS 240 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + S++EN G SI+RV A D D G N ++ Y + D D + + +D +G + T Sbjct: 241 YLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI-DWDAIQSNSI-FDLDSSTGVIRTK 298 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----XXFMP---GQYEVE 374 LD E + Y V A+DGG P ++ AT ++P G + Sbjct: 299 QNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIR 358 Query: 375 LAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 +E+ T + + TD D +++ +IT G+ G F + G I + +PLD + Sbjct: 359 -SENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFL-GFYFIQLQKPLDRE 416 Query: 433 QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 Y LT++ TD G RS V I++TD N+ +P F + YTA++ E A G+ VL Sbjct: 417 LVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQ 476 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 ++ATD D G N ++YS++ N+ F ++ Q+G +TT K LDRE +S +T Sbjct: 477 LNATDPDEGDNGTVSYSITG--GNDL-----GWFQVDFQSGLVTTAKPLDREQVSSVTIT 529 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 +TA+D G + +T V ++++D NDN+P F + Y Sbjct: 530 ITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSY 565 Score = 208 bits (507), Expect = 6e-53 Identities = 155/501 (30%), Positives = 224/501 (44%), Gaps = 23/501 (4%) Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 QF +S +G +S +D E L +R + PS + + + + D+NDN PRF Sbjct: 71 QFGFNSNTGVISTTARIDRETTTQISLQLRTLN---PS-NQPISVQVQVDDINDNEPRFP 126 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW- 317 T + + E++ + + A D D G N + YT+ D T L T P Sbjct: 127 TLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTL 186 Query: 318 -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 V T LDRET YQL +TATD G P F Y +A Sbjct: 187 CVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIA 246 Query: 377 EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 E+ PG ++ ++A D D + + Y I + + G+I Q LDF+ + Sbjct: 247 ENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVK 306 Query: 435 RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA---PYT---ASVFEDAPIGT 486 Y V A+D G ++D A V IN+ D N+ +P + P+ A E++ I T Sbjct: 307 NSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINT 366 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + + TD D N+Q +++ F I K LDRE + Sbjct: 367 NIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYF------IQLQKPLDRELVPF 420 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LT+ D GVPS S V I V DVNDN P F YTANI E A G+ V Q+ AT Sbjct: 421 YNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNAT 480 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G NG + Y + + + G F +D SG++ T K LDRE V++ + A D G+ P Sbjct: 481 DPDEGDNGTVSYSITGGN-DLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAP 539 Query: 667 QSSTVIVHIKIEDINDSPPVF 687 ++ + V + I D ND+ P F Sbjct: 540 KTGSTTVTVTIIDGNDNKPRF 560 Score = 199 bits (485), Expect = 3e-50 Identities = 151/496 (30%), Positives = 227/496 (45%), Gaps = 33/496 (6%) Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 +G + T+ ++DRET + L + + + P S + Y + Sbjct: 78 TGVISTTARIDRETTTQISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLY----YTLR 133 Query: 375 LAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ---NGRGLITVAQ-P 428 + E T P+ T T DA + + Y I G+ FS+ + G L + + P Sbjct: 134 IRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKP 193 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y L ++ATD G + INIT D N++APVF Y S+ E+ G Sbjct: 194 LDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGV 253 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 ++L VSA D D G N I Y++ + + F ++ TG I T + LD E + Sbjct: 254 SILRVSAADRDSGSNGDIKYAIDWD-----AIQSNSIFDLDSSTGVIRTKQNLDFEVKNS 308 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDALVGTSV 600 Y V A DGGVPS +D V I+V+D NDN P K A E++L+ T++ Sbjct: 309 YTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNI 368 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV-IRTNKALDRESVATHDLKAVA 659 + + TD D N + ++ D +EG F ++ I+ K LDRE V ++L Sbjct: 369 AYILVTDKDSNTNSQTELKITNGD-DEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNV 427 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G P +S+ V I + D+ND+ P F S+ T ISE + G+ + ++ A DPDEG N Sbjct: 428 TDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDN 487 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 V YSI GG+D F ++ + G + T LD E + I A S P Sbjct: 488 GTVSYSITGGNDLGWFQVDFQSGL----VTTAKPLDREQV-SSVTITITAQDHGSAPKTG 542 Query: 777 DVRVEILVTDVNDNAP 792 V + + D NDN P Sbjct: 543 STTVTVTIIDGNDNKP 558 Score = 188 bits (459), Expect = 4e-47 Identities = 143/480 (29%), Positives = 217/480 (45%), Gaps = 35/480 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I Q+ V D ND+ P F Y +RE TT ATD D G N V+YTI + Sbjct: 109 ISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTI--AS 166 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D + G + ++T+ LDRE Y + + ATD+ +P Sbjct: 167 GDN-----------TATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPA 215 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L I++ I+D+ND+ P F++ +Y S+ E + I ++ A D D G+N Sbjct: 216 ---LMGYCLINITILDENDHAPVFTQNSYLGSIAE--NTKPGVSILRVSAADRDSGSNGD 270 Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I+YAI Q F +DS +G + + LD+E SY + A DGG PS+++ + Sbjct: 271 IKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVT 330 Query: 245 INIRDVNDNAPRFYTSLF-----QESV-SENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 IN+ D NDN+P+ + +++ SEN I +I + D D N++ +T+ Sbjct: 331 INVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITN 390 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 D G + ++ LDRE Y L + TD G P RS Sbjct: 391 GDDEGCFKVEFL---GFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTD 447 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITS 416 F Y ++E G+ V+ L ATD DE DN + Y ITGGN G F + Sbjct: 448 VNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDF 507 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474 Q+ GL+T A+PLD +Q +T++A D G ++ + V + I D N+ P F + Y Sbjct: 508 QS--GLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSY 565 Score = 172 bits (418), Expect = 4e-42 Identities = 147/512 (28%), Positives = 224/512 (43%), Gaps = 30/512 (5%) Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y + E++PPGT V + A E G+ + +F S G+I+ +D Sbjct: 42 YTFHVQEEQPPGTYVGKVDGASAFE----------GSPK-QFGFNSNT--GVISTTARID 88 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 +E +++ + VQ+ + D N+ P F YT + E + TT + Sbjct: 89 --RETTTQISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPI 146 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 +ATD D G N + Y+++S N A T + T K LDRET Y L Sbjct: 147 NTATDPDAGNNGTVDYTIASG-DNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLN 205 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 +TA D G P+L + I+++D ND+ PVF Q Y +I E+ G S+ +V A D D Sbjct: 206 ITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDS 265 Query: 611 GLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G NG I Y +D + S F +D ++GVIRT + LD E ++ +A DGG P ++ Sbjct: 266 GSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKND 325 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFY------ISENSPIGTTIGEIRAHDPDEGPNAVVH 723 V I + D ND+ P + L + SENS I T I I D D N+ Sbjct: 326 LATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTE 385 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR-VEI 782 I GDD F +E G +L +D + P L + P + + V I Sbjct: 386 LKITNGDDEGCFKVEF-LGFYFIQLQKPLDREL-VPFYNLTLNVTDKGVPSRSTLGFVLI 443 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQYRILSGNNANL 839 VTDVNDN+P N + G + ++ A D D D + Y I GN+ Sbjct: 444 DVTDVNDNSPAFTS-NAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGW 502 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ +G +T + L+ T+ ++ D Sbjct: 503 FQVDFQSGLVTTAKPLDREQVSSVTITITAQD 534 Score = 167 bits (406), Expect = 1e-40 Identities = 117/369 (31%), Positives = 177/369 (47%), Gaps = 33/369 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I +LD NDH+PVF Y S+ E G ++L + A D+D G N +++Y I+ Sbjct: 224 ITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDW------ 277 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 DA +F +D +G + T+ +LD E YT V A+D P + L Sbjct: 278 ---DAIQS--------NSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDL 326 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD-----NPVIAKIKATDADVGANS 185 AT+ +N++D NDN PQ + TY + D ++ N IA I TD D NS Sbjct: 327 ---ATVTINVLDTNDNSPQL-KITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNS 382 Query: 186 AIRYAIIGGNTQMQFSIDSLSGD-VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I G+ + F ++ L + L K LD E V Y L + D G PSRS +L Sbjct: 383 QTELKITNGDDEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVL 442 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I++ DVNDN+P F ++ + ++SE G ++++ A D DEG N ++Y++ TG Sbjct: 443 IDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSI-----TGG 497 Query: 305 VDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 DL +D +SG V T+ LDRE + + +TA D G P++ + T Sbjct: 498 NDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNK 557 Query: 364 XXFMPGQYE 372 FM Y+ Sbjct: 558 PRFMKSSYK 566 Score = 130 bits (313), Expect = 2e-29 Identities = 105/339 (30%), Positives = 155/339 (45%), Gaps = 32/339 (9%) Query: 4 PFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63 P +H I + N+ PVF + A+V E A G +VL + ATD+D G + V Y Sbjct: 3121 PASVH--ILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKDKGPDGVVLY--H 3176 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ- 122 L+ +D Q F +D +G L LD E+ T+ V A + Sbjct: 3177 LLGSDN-----------------QQGFDLDSNTGTLSVSGDLDNERAGIVTLRVIAKNLF 3219 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 + V+ + ATI V + D ND P+F + Y+ V E + V+ + A D D Sbjct: 3220 QNSVTPSSVAHATIVVTVTDANDP-PRFLKSVYSAHVTEGSRI--GHVVTNVTAVDDDSD 3276 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 S IRY I GNT F +D+++G V LD E + YRL + A D G+P + Sbjct: 3277 IRS-IRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATDNGTPPMTGNAT 3335 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDY 301 L++ + D+NDN P V+EN P G ++ + A D D N Y+++ DY Sbjct: 3336 LVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDLNPNRGPFKYSISGSDY 3395 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 G+ L ++ SG V T LDRE Q Y + + TD Sbjct: 3396 -GSFRLNVS----SGVVSTVKSLDREKQDAYNISIKVTD 3429 Score = 57.6 bits (133), Expect = 1e-07 Identities = 51/183 (27%), Positives = 83/183 (45%), Gaps = 25/183 (13%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC C G+TG NC+ + C+ S C S C + C D Sbjct: 3758 YTCTCKPGYTGQNCDVDIN--YCQ----SSPCMYNSTC----KDLPTSFECVCDFGGRGE 3807 Query: 1102 VCELRARSFPVSSFLTFP---GLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLA 1156 CE+ + F +S++ FP G+ ++ ++ ++F+T + +GLL YN G DF+A Sbjct: 3808 RCEISSFGFEPASYMLFPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIA 3867 Query: 1157 LELVSSEAGRGGGPGLRFSFSLG--GGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDD 1214 LE+V L FS++LG G I + V DG WH V + + +++D Sbjct: 3868 LEIVERY--------LWFSYNLGYTGIPEVIKSDRAVTDGKWHHVTVIRDKKKGELLVDG 3919 Query: 1215 CDK 1217 +K Sbjct: 3920 SNK 3922 Score = 53.6 bits (123), Expect = 2e-06 Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 3/69 (4%) Query: 1282 VGCISDF--YIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339 VG I DF Y+ ++ G + CP K S C+ +PC NG C D W Y C+C Sbjct: 3943 VGGIKDFDAYLSDSRKHMHEAREKEGVMNRCPRK-SWCTWSPCDNGGTCVDTWLDYYCEC 4001 Query: 1340 KEGHTGKDC 1348 +G +G++C Sbjct: 4002 PDGFSGRNC 4010 Score = 50.4 bits (115), Expect = 2e-05 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%) Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568 +S DC + C C + S C+C G G C + C PC A D TP Sbjct: 3697 ESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLCESDIDECLTNPCKHASAC-DNTP 3755 Query: 1569 KGYSCACEPGYT 1580 GY+C C+PGYT Sbjct: 3756 GGYTCTCKPGYT 3767 Score = 48.8 bits (111), Expect = 6e-05 Identities = 57/260 (21%), Positives = 99/260 (38%), Gaps = 31/260 (11%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369 C + C S+PC + C DL ++ C C G G+ C S+ FG F P Sbjct: 3771 CDVDINYCQSSPCMYNSTCKDLPTSFECVCDFGGRGERCEISS-----FG------FEPA 3819 Query: 1370 LRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETM----YLPMATLSDGAWHR 1425 + P L ++ +T S +GLL Y+ +G ++ + + W Sbjct: 3820 SYML-FPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIALEIVERYLWFS 3878 Query: 1426 IEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFE-- 1483 + + G + D + + I+ + G++L+ G + G + D GF + Sbjct: 3879 YNLGYTGIPEVIKSDRAVTDGKWHHV-TVIRDKKKGELLVDGSNKKTGEV--DGGFTQLE 3935 Query: 1484 --------GCIQ--DVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWD 1533 G I+ D + ++ ++ +E V + C ++ C S C CV +W Sbjct: 3936 LNQSPLLVGGIKDFDAYLSDSRKHMHEAREKEGVMNRCPRKSWCTWSPCDNGGTCVDTWL 3995 Query: 1534 SSTCTCEAGRVGPQCVSACE 1553 C C G G C A E Sbjct: 3996 DYYCECPDGFSGRNCEKAME 4015 Score = 45.2 bits (102), Expect = 8e-04 Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 28/207 (13%) Query: 1390 AFV-MSIQLKSGLLHYSYNG----ETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLR 1444 AF+ +I + SG + YS+ +T+ + +++G W + ++ I + Sbjct: 4123 AFIEKTIAIASGKVTYSFRAGEASQTLTVTTLDVTNGNWQNVTLERDARTIRLATGTEFT 4182 Query: 1445 TVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPT-- 1502 + + G I + +GG + + F+GC++D++I + +N P Sbjct: 4183 QREFAVTPHNFLGANIRQWSLGGATQVPSGVTLEK--FKGCMEDLKINGVNTPMNGPNRF 4240 Query: 1503 ----VREN-VRDGCQSRADCMLSIC---PPYSKCVTSWDSSTCTCEAGRVGPQCVSACEL 1554 R V +GC + C S C + C WDS TC A C+ Sbjct: 4241 LSAEARGGAVTEGCVTSGQCQSSPCANNKEKTACYEDWDSYTCVSAA---------PCQP 4291 Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGYT 1580 PC A C P Q + + C C YT Sbjct: 4292 DPCKNNATCKP-QKDETFLCVCVGNYT 4317 Score = 41.9 bits (94), Expect = 0.007 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C+S D C+ + C S C + TCTC+ G G C ++ C+ PC D Sbjct: 3733 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNCDVDINYCQSSPCMYNSTCKD- 3791 Query: 1567 TPKGYSCACEPG 1578 P + C C+ G Sbjct: 3792 LPTSFECVCDFG 3803 Score = 40.7 bits (91), Expect = 0.016 Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 30/149 (20%) Query: 1536 TCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592 TC+C+ G G QC V+ C PC D + C+C PGY T ES + Sbjct: 3683 TCSCKPGFTGSQCEESVNDCNPNPCRNEGTCTDNN-GSFKCSCIPGY---TGRLCESDID 3738 Query: 1593 ECPGGWWGGSACGPC----ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 EC PC ACD T G + C CK + + CQ + Sbjct: 3739 EC--------LTNPCKHASACDNTPGGY--------TCTCKPGYTGQNCDVDINYCQS-S 3781 Query: 1649 AGSENSSCE--AATGQCHCRPGVIGRACD 1675 NS+C+ + +C C G G C+ Sbjct: 3782 PCMYNSTCKDLPTSFECVCDFGGRGERCE 3810 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/39 (33%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C + PC + + C + Y C CK G+TG++C Sbjct: 3733 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNC 3771 Score = 37.1 bits (82), Expect = 0.20 Identities = 40/130 (30%), Positives = 54/130 (41%), Gaps = 32/130 (24%) Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCK 1629 +C+C+PG+T S C ES + P PC + T C NG KC C Sbjct: 3683 TCSCKPGFT--GSQCEESVNDCNPN---------PCRNEGT------CTDNNGSFKCSCI 3725 Query: 1630 ENHYK---PEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYAEV 1684 + ECL C A S+C+ G C C+PG G+ CD N Y + Sbjct: 3726 PGYTGRLCESDIDECLTNPCKHA----SACDNTPGGYTCTCKPGYTGQNCDVDIN-YCQS 3780 Query: 1685 TP---NSGCE 1691 +P NS C+ Sbjct: 3781 SPCMYNSTCK 3790 Score = 37.1 bits (82), Expect = 0.20 Identities = 14/39 (35%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C+ PC N C+D ++ C C G+TG+ C Sbjct: 3695 CEESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLC 3733 >SB_34906| Best HMM Match : Cadherin (HMM E-Value=0) Length = 3922 Score = 368 bits (905), Expect = e-101 Identities = 408/1539 (26%), Positives = 647/1539 (42%), Gaps = 165/1539 (10%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND P F++ Y+A VRE A GTTV+T+KATD+D G V Y ++ + Sbjct: 1786 DVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGS-------- 1837 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 + F ID SG L T+ S DRE + ++V+V A D+ + LS Sbjct: 1838 ------------DEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPG-ALSEEV 1884 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + V ++D+ND+ PQF + + SV E S T I ++ ATD D+G N+ + Y I GG Sbjct: 1885 AVKVLVVDENDSPPQFDQAEFQTSVSE--SATIGTSILEVVATDQDIGDNAKLEYFISGG 1942 Query: 195 NTQMQFSIDSLS------GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + + F++ ++S G+V + LD+E SY + + A DG S TT++LI I Sbjct: 1943 DGRFWFAVQTISKSGRTYGEVQVDARLDFETKSSYTIDVTATDGRF---SATTRVLITIT 1999 Query: 249 DVNDNAPRFYT--------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 D ND P F T ++ VSE G +++V A D D + + YT+ Sbjct: 2000 DANDIVPMFMTLTTPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD---SPNIQYTLEGSS 2056 Query: 301 YTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + G + T Q LDRE + V A DG + +A Sbjct: 2057 SYFTIAARQEGGKFVGIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDI 2113 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRGRFSI 414 F Y + E++ GT V+ + A D D+ + + Y +T N G+F I Sbjct: 2114 NDNQPRFPNSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTLTD-NAGGKFKI 2172 Query: 415 TSQNGRGLITVAQPLDFKQE-RRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471 + L+T + LD + + +TV ATD G S T + I +TDAN++APVF Sbjct: 2173 DANTA--LVTTEEILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTK 2230 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 + +V ED G V VSATD+D G NA++ + ++ NE A F ++P G Sbjct: 2231 RIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTH--GNEPAA-----FYVDPSKG 2283 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTAN 589 + +L+ Y LTVT D G+P LSD + V I++ D NDN P+F Y Sbjct: 2284 TVHVFDILNYTLRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKT 2343 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPAS-GVIRTNKAL 645 + ED VG+ V V A D D G N + +++ +P D E D +S G++RT L Sbjct: 2344 VAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGGNPDDLFEVVPNPDNSSLGIVRTRLPL 2403 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRE+ H L+ A D G + V + + D+ND+ P F+ I EN + Sbjct: 2404 DRETTPIHHLEITAKDTGG--LTGKAHVWLTLLDVNDNGPWFQPPFFVGKIKENVNVKQF 2461 Query: 706 IGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSD-KAELVTMVDLDYESPRKKY 763 + ++ A+DPD N A Y+I G S +F+ + ++ ++ + D E+ + Sbjct: 2462 VTKVSANDPDTKNNGAPFTYAIYNGTVSGNFAFDIATITNVTTDMSSSGTFDRET-MTTW 2520 Query: 764 ELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 + I P N V + V D NDN P II N+Y F GP + D Sbjct: 2521 TIGIAGTDSGRPAKSNFTYVYVDVQDDNDNEPYDGRMTIIVNSYNGKFRGGPIAKTYYRD 2580 Query: 821 ADVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG----VNE 875 AD D Y + S N ++ TTG ++ + + L V G NE Sbjct: 2581 ADYDGDVNTYTLQSQTGGNFFTVDTTTGEISAAKDIPVGEYSLVISVTEVNTGNPPRANE 2640 Query: 876 IK------AMMQLSVRLITEEMLLNSITVRLNDM-TAEQFLSPLLGFFIDGLAAIIPCPK 928 + + + VR IT + + NS+ ++++DM E F+ + L+ + Sbjct: 2641 VNFPKTVTSRATVIVRDITSKAVSNSVALQISDMRKVEYFVGDYHDVVVGELSRMFGVSS 2700 Query: 929 ENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLAR 988 I +FSVQ + + L+V F+ + E + P + V +R L Sbjct: 2701 SGIEVFSVQ-PSPIKVMALDVQFAVKTGSDE---------YTKPYDVIRVVTDNRERLTN 2750 Query: 989 LATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPE 1048 L ++V ++C E +C+ V++ +A + D + P +S T + Sbjct: 2751 LG-LKVTSIGIDMCALER-ERVGKCINVVETSSAYKIASGD--YGKVPAPASSITLVSMD 2806 Query: 1049 GFTGVNCETILTKA-SCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRA 1107 TI+ +C + C +G C G + C Y CE Sbjct: 2807 VVLRDKYVTIIEPGKNCSNENP---CLNGGTCHDTVPAG--WRVCQCPRGYRGPHCEQTT 2861 Query: 1108 RSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLALELVSS 1162 R+F +S++ P L L +F T+ GL+LY G N DFLA+ L Sbjct: 2862 RTFRGTSYIWLPKLTAYDIRELSFEFTTEFKDGLMLYQGPLKPGDNNGAKDFLAVFLDE- 2920 Query: 1163 EAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI--EYFNR-TITMILDDCDKVL 1219 G +R S +T N+ D WHTV+I + +R I +I+D C Sbjct: 2921 -----GHLVVRVSLGYEPITINMTRRPNLNDKEWHTVQIIRDVIDRKMIRVIIDRCQSAQ 2975 Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279 + K T +V +L+ GPLQIGG+ + + Sbjct: 2976 IVEENGRVFEKRDTCEITGRVKGRSV---------YLNGFGPLQIGGVETDLTFIGITTT 3026 Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339 F GCI + K DL + + GC + ++ E S + +C C Sbjct: 3027 GFRGCIRNIIDTEKMYDLRNPIKVVNAPEGCTLAGTCPNNCNDKGYCEPSLMAGKSMCVC 3086 Query: 1340 KEGHTGKDCADSTGPPW-------RFGGDGMLSFNPLLRPIQLPWLNA------LSIR-- 1384 G+TG+ C D + + +F G+ + L++P +P +N L ++ Sbjct: 3087 DFGYTGRACNDRSEANYYLENSFSQFLLTGIRARRELIQP-PVPLMNEYYTHINLQVKLD 3145 Query: 1385 --TRQRDAFVMS---------IQLKSGLLHYSYN-GETM---YLPMATLSDGAWHRIEIK 1429 T+ F+ S + +K +L Y + G+ M +P +SDG +H + + Sbjct: 3146 PGTKDCVLFLSSNSLGTEFNRLDVKDHMLRYIFRLGDRMKVLSIPQYNISDGKYHSVMVN 3205 Query: 1430 WLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGL 1468 G + +DY + K+ G I GGL Sbjct: 3206 REGNYAEMQIDYRAKMAGTTGGVQKLLNMGGGSIFTGGL 3244 Score = 309 bits (759), Expect = 2e-83 Identities = 253/837 (30%), Positives = 400/837 (47%), Gaps = 67/837 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D N ++PVF + AS + + T+V+ L D+D+G EV Y + Sbjct: 143 EVTVADTNTYTPVFSRTSFWASKPDTLPTDTSVMQLPIIDKDMGSLGEVTYQL------- 195 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++P + D FR+D SG + + L + Y + KA D SP Sbjct: 196 IDPTVSAGETSGY-----DRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPA--- 244 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI-KATDADVGANSAIR 188 L +T + +++ +D +FS+ Y+ S+ E+ +P+ ++ +AT G++S I Sbjct: 245 LEATVDVFISVYPSSDTPVRFSQNPYSASIAEN-----SPLNTEVFRATATKSGSSSGIA 299 Query: 189 YAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLL 244 Y+++GG N FSIDS SG V L++ LD E+ +SY+L +R GGS + + + L Sbjct: 300 YSLVGGQIENGNTMFSIDS-SGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATDVECL 358 Query: 245 INIRDVNDNAPRF-YTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + + DVNDN P F + + ++ V +N P I ++A D+DEG NA++T ++ T Sbjct: 359 VTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQG---T 415 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + PITID S + T+ +L T YQ+ V ATD G PP+ + T Sbjct: 416 VPSNAPITIDTPSNVLKTTTKLS--TVIDYQITVRATDKGSPPQYSEITVIVKVLNIQTP 473 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y V++ E+ G V+++ AT D + L Y GN F I S G Sbjct: 474 PV-FGQAKYTVDVQENTKVGQQVISVKATYGDSNGLLQYSFVSGNLGDAFCIDSS---GQ 529 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 ITVAQPLD + Y L V G D V +++TD N+ +P F + Y ED Sbjct: 530 ITVAQPLDREVLPSYTLRVRVA-LGNNEDFTEVFVSLTDINDDSPTFTKSVYEFFANEDI 588 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT--TNKLLD 540 GT++ V+ATD D G + QI+Y +++ +F ++ TG I+ + K LD Sbjct: 589 SSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSM----DKFDLDQTTGIISLASGKSLD 644 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E +S ++L V A D G LS +V I + D+NDN+P F Y A + DA V V Sbjct: 645 YEDISMHVLFVRAEDNGANKLSAIAEVRIYLRDINDNDPKFSAASYHAKLSLDAPVLEHV 704 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 QV ATD D NGRI Y + +EG+F + +G+IR K+L + ++ L A Sbjct: 705 VQVTATDLDTANNGRIRYSI-VAGNQEGAFQVLTDNGLIRVAKSLTTVAASSFLLTLEAA 763 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G P + +V V + + + D PP F D + +E + +A + Sbjct: 764 DSGDPERKGSVNVQVNV-FLPDGPPKFVLDPVIVNATEGIAANQRVAVAKA-----ATSE 817 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + Y I G+ ++ F++ G ++T +LDYE +I + V+V Sbjct: 818 ALKYEILSGNTNDMFAINPSSG----VILTTRELDYEEATGYIMNIIARDTRDRSASVQV 873 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG------RVPAYDADVTDKLQYRI 831 I V ++NDN P+ F N D GPF R+ A D D+ D++ Y+I Sbjct: 874 IINVVNINDNEPM---FPGETNGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKI 927 Score = 270 bits (661), Expect = 1e-71 Identities = 255/862 (29%), Positives = 387/862 (44%), Gaps = 94/862 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ P F + Y S++ GT+VLT+ ATD D G NA++ Y + Sbjct: 1583 EVEVQDVNDNYPSFITRAYLGSIQNTKPIGTSVLTVSATDPDAGDNAKITYAFK------ 1636 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSD 128 +P D F ID SG + T+ +L K V +V + +A D Sbjct: 1637 -SPNDK--------------FEIDSTSGDIRTKVALTGTKDVNEKMTVVASNTEAIQGGD 1681 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + V I + P + +T + E +SV N + K+ A +I Sbjct: 1682 ANNRDRETEVTIYITDLAPPVCDKNLFTARILESLSV--NSDVLKVSA---QAPGGKSIV 1736 Query: 189 YAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLI 245 Y+ + N + +FS+++ +G + LDYEQ+ SP ++ Q Sbjct: 1737 YSPVKANADIDEKFSVET-NGQIKTASQLDYEQL-------------SPGDKTFKLQCCD 1782 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVND+ P F + V EN PIG +++ ++A D D G +TY + Sbjct: 1783 TLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFL-----KAGS 1837 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXX 363 D ID SG + T DRE Q+ + ++V A D G+ P S Sbjct: 1838 DEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSP 1897 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI--TSQNG 419 F +++ ++E GT ++ + ATD D ++ +L Y I+GG+ R F++ S++G Sbjct: 1898 PQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQTISKSG 1957 Query: 420 R--GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN------ 471 R G + V LDF+ + Y + V+ATD G S T V I ITDAN+ P+F Sbjct: 1958 RTYGEVQVDARLDFETKSSYTIDVTATD-GRFSATTRVLITITDANDIVPMFMTLTTPTL 2016 Query: 472 -AP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 +P YT V E G VL V A D+D N Q T SS A +FV Sbjct: 2017 LSPIYTGRVSEMTGSGVEVLKVYAVDTD-SPNIQYTLEGSSSYFTIAARQEGGKFV---- 2071 Query: 530 TGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 G I+T ++ LDRE + V A+DG + + +EI+V D+NDN+P F LY Sbjct: 2072 -GIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFPNSLYVG 2127 Query: 589 NIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 + E+ GTSV V A D D +G N I Y L D G F ID + ++ T + L Sbjct: 2128 YVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTL--TDNAGGKFKIDANTALVTTEEIL 2185 Query: 646 DRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 DRE S + + +A D G S+T + I + D ND PVF +SE+ G Sbjct: 2186 DRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGY 2245 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + + A D D GPNA + + + G++ +F ++ +G+ V + D+ + RK Y Sbjct: 2246 VVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGT-----VHVFDILNYTLRKSYN 2300 Query: 765 LVIRAA--SPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 L + + P+ +D V I +TD NDNAP+ Q +D P V A Sbjct: 2301 LTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAV 2360 Query: 820 DADVTD--KLQYRILSGNNANL 839 D D D K + I GN +L Sbjct: 2361 DYDSGDNAKFVFDITGGNPDDL 2382 Score = 252 bits (616), Expect = 4e-66 Identities = 253/899 (28%), Positives = 401/899 (44%), Gaps = 102/899 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NV N + P F + +A+++E G + T+ ATD+D G+N EVEY I V Sbjct: 1474 RVNVEYKNMYRPEFT-KCGKATIQENLLKGQLIATVTATDRDQGRNGEVEYKIVPVGG-- 1530 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVS 127 QD F I+ ++G ++T +SLDRE A YTV++ A D + Sbjct: 1531 -----------------QDFFTINNKTGEVITTSSLDRETKATYTVIITAEDGGHGKDPA 1573 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 +RL S + V + D NDNYP F + Y S+ + + + + ATD D G N+ I Sbjct: 1574 ERLMSYCFLEVEVQDVNDNYPSFITRAYLGSIQNTKPIGTS--VLTVSATDPDAGDNAKI 1631 Query: 188 RYAIIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRA-----QDGGSPSRSNTT 241 YA N +F IDS SGD+ + V + V V+ + Q G + +R T Sbjct: 1632 TYAFKSPND--KFEIDSTSGDIRTKVALTGTKDVNEKMTVVASNTEAIQGGDANNRDRET 1689 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ I I D+ P +LF + E++ + +++V A A G + Y+ Sbjct: 1690 EVTIYITDL--APPVCDKNLFTARILESLSVNSDVLKVSA-QAPGG--KSIVYS----PV 1740 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 N D ID + V T+GQ+ +Q Y+ L GD ++ Sbjct: 1741 KANAD----IDEKFS-VETNGQIKTASQLDYEQL----SPGD--KTFKLQCCDTLEDVND 1789 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419 F G Y+ + E+ P GT V+T+ ATD D + + Y + G+ F+I + Sbjct: 1790 DKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSDE-HFAIDVNS- 1847 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYT 475 G +T + D + + + + V A D G S+ V++ + D N+ P F+ A + Sbjct: 1848 -GTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQ 1906 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT-GAIT 534 SV E A IGT++L V ATD D+G NA++ Y +S A Q + +T G + Sbjct: 1907 TSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFA--VQTISKSGRTYGEVQ 1964 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK--------QQLY 586 + LD ET S Y + VTA DG S TT V I++ D ND P+F +Y Sbjct: 1965 VDARLDFETKSSYTIDVTATDG---RFSATTRVLITITDANDIVPMFMTLTTPTLLSPIY 2021 Query: 587 TANIMEDALVGTSVSQVGATDAD-----VGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 T + E G V +V A D D L G Y +E G FV G+I T Sbjct: 2022 TGRVSEMTGSGVEVLKVYAVDTDSPNIQYTLEGSSSYFTIAARQEGGKFV-----GIIST 2076 Query: 642 -NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 ++ LDRE+ +A DG + + + I + DIND+ P F + Y+ EN Sbjct: 2077 GSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENK 2133 Query: 701 PIGTTIGEIRAHDPDE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 GT++ ++AHD D+ G NA + Y++ + F ++ ++ A + T LD E Sbjct: 2134 AAGTSVMYVQAHDDDDPYLGGNAEIRYTLT-DNAGGKFKID----ANTALVTTEEILDRE 2188 Query: 758 SPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814 + + + + A + L I VTD ND+APV +D P Sbjct: 2189 TSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVT 2248 Query: 815 RVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 V A D D +L++ + GN ++ + G++ + LN + K + V+V+D Sbjct: 2249 SVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVFDILNYTLRKSYNLTVTVSD 2307 Score = 223 bits (546), Expect = 1e-57 Identities = 210/803 (26%), Positives = 333/803 (41%), Gaps = 45/803 (5%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 S D E +Y + + A +P + ++S++ + + I D+ D PQFS+ Y VSV ED Sbjct: 3 SFDYETADKYRIQISAQSGTAP--NIMTSSSDVAITIKDEKDP-PQFSQSEYKVSVPEDA 59 Query: 164 SVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQF-SIDSLSGDVSLV--KTLDYEQ 219 SV + I+ D D + + + + S+ G+ V KTLD Sbjct: 60 SVRST-LSRGIRFVDEDTLSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLDTFV 118 Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 + ++ D P TT++ + + D N P F + F S + +P S++++ Sbjct: 119 ASKFTFDMKVTDKNFPGMFATTKVEVTVADTNTYTPVFSRTSFWASKPDTLPTDTSVMQL 178 Query: 280 QAYDADEGVNAELTYTMTDKDY----TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 D D G E+TY + D T D +D SG + ++ L T Y+L Sbjct: 179 PIIDKDMGSLGEVTYQLIDPTVSAGETSGYD-RFRVDD-SGMIESTNILTANT--LYKLQ 234 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 A DGG P AT F Y +AE+ P T V TAT + Sbjct: 235 AKAKDGGSPALEATVDVFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATATKSGS 294 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM- 454 + + Y + GG ++ S + G + + + LD ++ + Y L V T +GG A Sbjct: 295 SSGIAYSLVGGQIENGNTMFSIDSSGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATD 354 Query: 455 --VQINITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDSDVGINAQITYSLSS 510 + +TD N+ P+F D AP T + + A DSD G NAQ+T S+ Sbjct: 355 VECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQG 414 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 + + A D P TT KL T+ Y +TV A D G P V + Sbjct: 415 TVPSNAPITID-----TPSNVLKTTTKL---STVIDYQITVRATDKGSPPQYSEITVIVK 466 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V+++ PVF Q YT ++ E+ VG V V AT D NG + Y + + +F Sbjct: 467 VLNI-QTPPVFGQAKYTVDVQENTKVGQQVISVKATYGD--SNGLLQYSFVSGNLGD-AF 522 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 ID +SG I + LDRE + ++ L+ G + V + + DIND P F Sbjct: 523 CID-SSGQITVAQPLDREVLPSYTLRVRVALGNNEDFTE---VFVSLTDINDDSPTFTKS 578 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF-SLETRQGSDKAELV 749 F+ +E+ GT+IG++ A D D G + + Y D S + Q + L Sbjct: 579 VYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGIISLA 638 Query: 750 TMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 + LDYE + L +RA + L V I + D+NDN P D Sbjct: 639 SGKSLDYED-ISMHVLFVRAEDNGANKLSAIAEVRIYLRDINDNDPKFSAASYHAKLSLD 697 Query: 807 CFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864 + +V A D D + +++Y I++GN + G + ++ L T Sbjct: 698 APVLEHVVQVTATDLDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVAKSLTTVAASSFL 757 Query: 865 MEVSVTD-GVNEIKAMMQLSVRL 886 + + D G E K + + V + Sbjct: 758 LTLEAADSGDPERKGSVNVQVNV 780 Score = 221 bits (541), Expect = 5e-57 Identities = 237/898 (26%), Positives = 389/898 (43%), Gaps = 75/898 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69 I + D D P F +Y+ SV E AS +T+ ++ D+D + ++E ++E +T+ Sbjct: 35 ITIKDEKD-PPQFSQSEYKVSVPEDASVRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRI 92 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D VQD G + +LD +++T +K TD+ P Sbjct: 93 --PLD-------YLSVVQD-----GGECKFVIEKTLDTFVASKFTFDMKVTDKNFP---G 135 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + +T + V + D N P FS ++ S + + TD V+ ++ D D+G+ + Y Sbjct: 136 MFATTKVEVTVADTNTYTPVFSRTSFWASKPDTLP-TDTSVM-QLPIIDKDMGSLGEVTY 193 Query: 190 AII-----GGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 +I G T +F +D SG + L + Y+L +A+DGGSP+ T Sbjct: 194 QLIDPTVSAGETSGYDRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPALEATVD 250 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + I++ +D RF + + S++EN P+ + R A G ++ + Y++ Sbjct: 251 VFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATA--TKSGSSSGIAYSLVGGQIE 308 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT-DGGDPPRSATATXXXXXXXXXX 361 N + +ID SG V QLDRE Y+L V T GG + Sbjct: 309 -NGNTMFSIDS-SGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATDVECLVTVTDVND 366 Query: 362 XXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQN 418 F + + D P T + TL A D+DE ++ G IT Sbjct: 367 NTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQGTVPSNAPITIDT 426 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTAS 477 ++ L + Y +TV ATD G + + + + N PVF A YT Sbjct: 427 PSNVLKTTTKLSTVID--YQITVRATDKGSPPQYSEITVIVKVLNIQTPPVFGQAKYTVD 484 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+ +G V+ V AT D N + YS S +A F I+ +G IT + Sbjct: 485 VQENTKVGQQVISVKATYGDS--NGLLQYSFVSGNLGDA-------FCID-SSGQITVAQ 534 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + Y L V G + D T+V +S+ D+ND+ P F + +Y ED G Sbjct: 535 PLDREVLPSYTLRVRVALG---NNEDFTEVFVSLTDINDDSPTFTKSVYEFFANEDISSG 591 Query: 598 TSVSQVGATDADVGLNGRIHYE-LDPKDREE-GSFVIDPASGVIR--TNKALDRESVATH 653 TS+ +V ATD D G +G+I Y L D + F +D +G+I + K+LD E ++ H Sbjct: 592 TSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGIISLASGKSLDYEDISMH 651 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L A D G S+ V I + DIND+ P F + +S ++P+ + ++ A D Sbjct: 652 VLFVRAEDNGANKLSAIAEVRIYLRDINDNDPKFSAASYHAKLSLDAPVLEHVVQVTATD 711 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKKYELVIRAAS- 771 D N + YSI G+ +F + T G + A+ +T V + L + AA Sbjct: 712 LDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVAKSLTTV------AASSFLLTLEAADS 765 Query: 772 --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829 P V V++ V + D P +I N + + RV A ++ L+Y Sbjct: 766 GDPERKGSVNVQVNVF-LPDGPPKFVLDPVIVNATEG---IAANQRVAVAKAATSEALKY 821 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 ILSGN ++ +N ++G + + +L+ M + D + A +Q+ + ++ Sbjct: 822 EILSGNTNDMFAINPSSGVILTTRELDYEEATGYIMNIIARD-TRDRSASVQVIINVV 878 Score = 195 bits (476), Expect = 4e-49 Identities = 208/844 (24%), Positives = 350/844 (41%), Gaps = 85/844 (10%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80 PVF +Y V+E G V+++KAT D N ++Y+ Sbjct: 474 PVFGQAKYTVDVQENTKVGQQVISVKATYGD--SNGLLQYSF------------------ 513 Query: 81 XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140 + D F ID SG + LDRE + YT+ V+ + + T + V++ Sbjct: 514 -VSGNLGDAFCIDS-SGQITVAQPLDREVLPSYTLRVRVA-----LGNNEDFTE-VFVSL 565 Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQ 197 D ND+ P F++ Y +EDIS I K+ ATD D G++ I Y + + + Sbjct: 566 TDINDDSPTFTKSVYEFFANEDIS--SGTSIGKVAATDRDSGSHGQISYRFLYASDIQSM 623 Query: 198 MQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 +F +D +G +SL K+LDYE + + L +RA+D G+ S ++ I +RD+NDN P Sbjct: 624 DKFDLDQTTGIISLASGKSLDYEDISMHVLFVRAEDNGANKLSAIAEVRIYLRDINDNDP 683 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 +F + + +S + P+ +V+V A D D N + Y++ GN + + + Sbjct: 684 KFSAASYHAKLSLDAPVLEHVVQVTATDLDTANNGRIRYSIV----AGNQEGAFQVLTDN 739 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 G + + L + + L + A D GDP R + F+ V Sbjct: 740 GLIRVAKSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNVFLPDGPPK-FVLDPVIVNA 798 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 E V A ++ L YEI GNT F+I +G +I + LD+++ Sbjct: 799 TEGIAANQRVAVAKAATSEA---LKYEILSGNTNDMFAINPSSG--VILTTRELDYEEAT 853 Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE---NAPYTASVFEDAPIGTTVLVVS 492 Y++ + A D+ RS + V IN+ + N+ P+F N V G ++ Sbjct: 854 GYIMNIIARDTRDRSASVQVIINVVNINDNEPMFPGETNGQIDRKVAGPFAPGVIATRLT 913 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A D D+G ++ Y +S E N F I+ + I N L + S + T+ Sbjct: 914 AVDKDIG--DRVYYKISIEAEN--------YFTIDERGQLICKNDL--KGIASPFRFTIE 961 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 ARDGG+P T +V + V+ KQQ + E GT +++V G Sbjct: 962 ARDGGLPQKVHTANVLLVFVNYRP-----KQQPVRVIVPETTRAGTVITRV-PRYFPTG- 1014 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 E E+ +F ID G + N+ LD E +A L V + P + + Sbjct: 1015 ------EFSIVYPEKTNFTID-NDGNVTLNRPLDYEEIA-FTLITVREKQASGPLENYID 1066 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V I + D ND+ P F ++ NS G T +++A D D G N ++ + ++ Sbjct: 1067 VEITVLDENDNAPFFTMISTLGRVNSNSRAGATAFQLQARDLDSGSNGLIGFQLENIPTL 1126 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 + TRQ + + ++ R +++ P N + + + V + P Sbjct: 1127 FMINPLTRQ-------IEVGQPRLQTSRYGLDIIPFDYGKPSVNGTKATVDIETV-QSPP 1178 Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852 V + F + + G V A +L Y I+ GN + L + G + L+ Sbjct: 1179 VFNESSYTFTVSERAPTMTKIGDVTAVSVSGA-RLSYTIIEGNTGDKFLAKD-NGDIVLN 1236 Query: 853 PQLN 856 L+ Sbjct: 1237 SLLD 1240 Score = 195 bits (475), Expect = 5e-49 Identities = 214/850 (25%), Positives = 366/850 (43%), Gaps = 92/850 (10%) Query: 96 SGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 +G ++ + LD E+ + + + V+A +Q + LSS + + +I+ ND +P F + Sbjct: 1230 NGDIVLNSLLDFERDQSVFNLKVEAKEQ---IPKGLSSEVDVTITVINANDFHPYFDDPV 1286 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGAN-----SAIRYAIIGGNTQMQFSIDSLSGDV 209 Y + V E V D VI + A D D ++ ++Y++ G + F ID +G + Sbjct: 1287 YRLKVPESRGVGD--VIMTVTARDCDCPSDCTCPVGQLKYSVEAGTS---FDIDQ-TGAI 1340 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + +TLDYE + L + A D G + T +++ + D NDNAP F + + ++ + Sbjct: 1341 VVARTLDYETSKVQVLKVMASDQGEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTAD 1400 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 G I V A D D+ ++ Y++ ++ +G + + L + Sbjct: 1401 ASTGSMIGAVIARDQDQDDIEKVRYSVVS-------GTEFNVNTETGVLTVAKDLSTGAK 1453 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 ++Y + + ATD +S A F + + E+ G + T+T Sbjct: 1454 SEYSMEIRATDS---TKSNDARVRVNVEYKNMYRPEFTKCG-KATIQENLLKGQLIATVT 1509 Query: 390 ATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 ATD D+ + + Y+I + F+I ++ G + T LD + + Y + ++A D G Sbjct: 1510 ATDRDQGRNGEVEYKIVPVGGQDFFTINNKTGEVITT--SSLDRETKATYTVIITAEDGG 1567 Query: 448 GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 D A +++ + D N+ P F Y S+ PIGT+VL VSATD D G Sbjct: 1568 HGKDPAERLMSYCFLEVEVQDVNDNYPSFITRAYLGSIQNTKPIGTSVLTVSATDPDAGD 1627 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLTVTARD 555 NA+ITY+ S + +F I+ +G I T L E M+ A Sbjct: 1628 NAKITYAFKSP---------NDKFEIDSTSGDIRTKVALTGTKDVNEKMTVVASNTEAIQ 1678 Query: 556 GGVPSLSD-TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 GG + D T+V I + D+ PV + L+TA I+E V + V +V A G Sbjct: 1679 GGDANNRDRETEVTIYITDL--APPVCDKNLFTARILESLSVNSDVLKVSAQAP--GGKS 1734 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 ++ + + F ++ +G I+T LD E ++ D ++ + Sbjct: 1735 IVYSPVKANADIDEKFSVE-TNGQIKTASQLDYEQLSPGD------------KTFKLQCC 1781 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 +ED+ND P F+ + EN+PIGTT+ I+A D D G VV Y +K G D + Sbjct: 1782 DTLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSDEH- 1840 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVI---RAASP-PLWNDVRVEILVTDVNDN 790 F+++ G+ L T D E +VI + +P L +V V++LV D ND+ Sbjct: 1841 FAIDVNSGT----LTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDS 1896 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN------ANLILL 842 P + + + V A D D+ D KL+Y I G+ + Sbjct: 1897 PPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQTISKS 1956 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLND 902 T G + + +L+ T++V+ TDG + R++ N I Sbjct: 1957 GRTYGEVQVDARLDFETKSSYTIDVTATDG------RFSATTRVLITITDANDIVPMFMT 2010 Query: 903 MTAEQFLSPL 912 +T LSP+ Sbjct: 2011 LTTPTLLSPI 2020 Score = 184 bits (448), Expect = 9e-46 Identities = 183/674 (27%), Positives = 303/674 (44%), Gaps = 59/674 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID L R LD E++A + V+ + P+ + + + + ++D+NDN P Sbjct: 1026 FTIDNDGNVTLNRP-LDYEEIAFTLITVREKQASGPLENYID----VEITVLDENDNAPF 1080 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F+ + V+ + +++A D D G+N I + + N F I+ L+ + Sbjct: 1081 FTMISTLGRVNSNSRA--GATAFQLQARDLDSGSNGLIGFQL--ENIPTLFMINPLTRQI 1136 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + + Q Y L I D G PS N T+ ++I V + P F S + +VSE Sbjct: 1137 EVGQ--PRLQTSRYGLDIIPFDYGKPS-VNGTKATVDIETV-QSPPVFNESSYTFTVSER 1192 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-T 328 P I V A A L+YT+ + + TG+ L +G + + LD E Sbjct: 1193 APTMTKIGDVTAVSVS---GARLSYTIIEGN-TGDKFLA----KDNGDIVLNSLLDFERD 1244 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Q+ + L V A + S+ F Y +++ E G ++T+ Sbjct: 1245 QSVFNLKVEAKEQIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIMTV 1304 Query: 389 TATDAD--ED-----NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 TA D D D +L Y + G + F I + G I VA+ LD++ + VL V Sbjct: 1305 TARDCDCPSDCTCPVGQLKYSVEAGTS---FDI---DQTGAIVVARTLDYETSKVQVLKV 1358 Query: 442 SATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 A+D G + TA+ V + + D N+ APVF+ Y + DA G+ + V A D D Sbjct: 1359 MASDQGEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQD 1418 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 ++ YS+ S +F +N +TG +T K L S Y + + A D Sbjct: 1419 DIEKVRYSVVS----------GTEFNVNTETGVLTVAKDLSTGAKSEYSMEIRATDS--- 1465 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 + S+ V ++V N P F + A I E+ L G ++ V ATD D G NG + Y+ Sbjct: 1466 TKSNDARVRVNVEYKNMYRPEF-TKCGKATIQENLLKGQLIATVTATDRDQGRNGEVEYK 1524 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG---TPPQ--SSTVIVH 674 + P ++ F I+ +G + T +LDRE+ AT+ + A DGG P + S + Sbjct: 1525 IVPVGGQD-FFTINNKTGEVITTSSLDRETKATYTVIITAEDGGHGKDPAERLMSYCFLE 1583 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 ++++D+ND+ P F + I PIGT++ + A DPD G NA + Y+ K +D Sbjct: 1584 VEVQDVNDNYPSFITRAYLGSIQNTKPIGTSVLTVSATDPDAGDNAKITYAFKSPND--K 1641 Query: 735 FSLETRQGSDKAEL 748 F +++ G + ++ Sbjct: 1642 FEIDSTSGDIRTKV 1655 Score = 178 bits (434), Expect = 5e-44 Identities = 225/892 (25%), Positives = 366/892 (41%), Gaps = 103/892 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ P F Y A + A V+ + ATD D N + Y+I V Sbjct: 672 RIYLRDINDNDPKFSAASYHAKLSLDAPVLEHVVQVTATDLDTANNGRIRYSI--VAG-- 727 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E A F++ +G + SL + + + ++A D P +R Sbjct: 728 -NQEGA--------------FQVLTDNGLIRVAKSLTTVAASSFLLTLEAADSGDP--ER 770 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S + VN+ D P+F V+ E I+ +AK ++A ++Y Sbjct: 771 KGSV-NVQVNVFLP-DGPPKFVLDPVIVNATEGIAANQRVAVAKAATSEA-------LKY 821 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GNT F+I+ SG + + LDYE+ Y + I A+D + RS + Q++IN+ + Sbjct: 822 EILSGNTNDMFAINPSSGVILTTRELDYEEATGYIMNIIARD--TRDRSASVQVIINVVN 879 Query: 250 VNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 +NDN P F V+ G R+ A D D G ++ ++Y Sbjct: 880 INDNEPMFPGETNGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISIEAENY----- 934 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 TID R G + L + + ++ + A DGG P + TA + Sbjct: 935 --FTIDER-GQLICKNDL-KGIASPFRFTIEARDGGLPQKVHTANVLLVFVN-------Y 983 Query: 367 MPGQYEVELAEDEPP--GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 P Q V + E GT + + + + Y + F+I + G +T Sbjct: 984 RPKQQPVRVIVPETTRAGTVITRVPRYFPTGEFSIVYP-----EKTNFTIDND---GNVT 1035 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAP 483 + +PLD+++ ++TV + G + + V+I + D N+ AP F V ++ Sbjct: 1036 LNRPLDYEEIAFTLITVREKQASGPLENYIDVEITVLDENDNAPFFTMISTLGRVNSNSR 1095 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G T + A D D G N I + L + + F+INP T I + R Sbjct: 1096 AGATAFQLQARDLDSGSNGLIGFQLENIPT---------LFMINPLTRQIEVGQ--PRLQ 1144 Query: 544 MSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y L + D G PS++ T V+I V + PVF + YT + E A T + Sbjct: 1145 TSRYGLDIIPFDYGKPSVNGTKATVDIETVQ---SPPVFNESSYTFTVSERAPTMTKIGD 1201 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVAID 661 V A R+ Y + + G + +G I N LD E + +LK A + Sbjct: 1202 VTAVSVS---GARLSYTII--EGNTGDKFLAKDNGDIVLNSLLDFERDQSVFNLKVEAKE 1256 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-----E 716 SS V V I + + ND P F+ + E+ +G I + A D D Sbjct: 1257 QIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIMTVTARDCDCPSDCT 1316 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-ASPPLW 775 P + YS++ G SF ++ +V LDYE+ + + V+ + ++ Sbjct: 1317 CPVGQLKYSVEAG---TSFDID-----QTGAIVVARTLDYETSKVQVLKVMASDQGEKVF 1368 Query: 776 NDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRIL 832 V V + + D NDNAPV K +F D G V A D D D K++Y ++ Sbjct: 1369 TAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQDDIEKVRYSVV 1428 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 SG N+ N TG +T++ L+T +ME+ TD A ++++V Sbjct: 1429 SGTEFNV---NTETGVLTVAKDLSTGAKSEYSMEIRATDSTKSNDARVRVNV 1477 Score = 167 bits (405), Expect = 1e-40 Identities = 177/651 (27%), Positives = 279/651 (42%), Gaps = 50/651 (7%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F+ID+ G+V+L + LDYE++ + +R + P N + I + D NDNAP F Sbjct: 1026 FTIDN-DGNVTLNRPLDYEEIAFTLITVREKQASGPLE-NYIDVEITVLDENDNAPFFTM 1083 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 V+ N G + ++QA D D G N + + + N+ I+P + + Sbjct: 1084 ISTLGRVNSNSRAGATAFQLQARDLDSGSNGLIGFQLE------NIPTLFMINPLTRQIE 1137 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 GQ +T ++Y L + D G P S T F Y ++E Sbjct: 1138 V-GQPRLQT-SRYGLDIIPFDYGKP--SVNGTKATVDIETVQSPPVFNESSYTFTVSERA 1193 Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR-YV 438 P T + +TA RL Y I GNT +F + NG I + LDF++++ + Sbjct: 1194 PTMTKIGDVTAVSVS-GARLSYTIIEGNTGDKF-LAKDNGD--IVLNSLLDFERDQSVFN 1249 Query: 439 LTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 L V A + G S V I + +AN++ P F++ Y V E +G ++ V+A D Sbjct: 1250 LKVEAKEQIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIMTVTARDC 1309 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D + + S EA D QTGAI + LD ET +L V A D Sbjct: 1310 DCPSDCTCPVG-QLKYSVEAGTSFDID-----QTGAIVVARTLDYETSKVQVLKVMASDQ 1363 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G + T V +++ D NDN PVFK+ Y + DA G+ + V A D D ++ Sbjct: 1364 GEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQDDIEKV 1423 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y + F ++ +GV+ K L + + + ++ A D +S+ V + Sbjct: 1424 RYSV----VSGTEFNVNTETGVLTVAKDLSTGAKSEYSMEIRATDS---TKSNDARVRVN 1476 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 +E N P F + C I EN G I + A D D+G N V Y I + F+ Sbjct: 1477 VEYKNMYRPEF-TKCGKATIQENLLKGQLIATVTATDRDQGRNGEVEYKIVPVGGQDFFT 1535 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRA--------ASPPLWNDVRVEILVTDVN 788 + + G E++T LD E+ + Y ++I A + L + +E+ V DVN Sbjct: 1536 INNKTG----EVITTSSLDRET-KATYTVIITAEDGGHGKDPAERLMSYCFLEVEVQDVN 1590 Query: 789 DNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSGNN 836 DN P + + ++ P+G V A D D D K+ Y S N+ Sbjct: 1591 DNYPSFIT-RAYLGSIQNTKPIGTSVLTVSATDPDAGDNAKITYAFKSPND 1640 Score = 163 bits (395), Expect = 2e-39 Identities = 175/700 (25%), Positives = 310/700 (44%), Gaps = 50/700 (7%) Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 +++ DYE YR+ I AQ G +P+ ++++ + I I+D D P+F S ++ SV E+ Sbjct: 1 MRSFDYETADKYRIQISAQSGTAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEDA 59 Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQLDRETQ 329 + ++ R + ++ ++ +L +M + +D L + D LD Sbjct: 60 SVRSTLSRGIRFVDEDTLSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLDTFVA 119 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 +K+ + TD P AT F + + P T V+ L Sbjct: 120 SKFTFDMKVTDKNFPGMFATTKVEVTVADTNTYTPVFSRTSFWASKPDTLPTDTSVMQLP 179 Query: 390 ATDADEDN--RLHYE-----ITGGNTRG--RFSITSQNGRGLITVAQPLDFKQERRYVLT 440 D D + + Y+ ++ G T G RF + + G+I L Y L Sbjct: 180 IIDKDMGSLGEVTYQLIDPTVSAGETSGYDRFRV---DDSGMIESTNIL--TANTLYKLQ 234 Query: 441 VSATDSGGRSDTAMVQINIT-DANNYAPV-FENAPYTASVFEDAPIGTTVLVVSATDSDV 498 A D G + A V + I+ ++ PV F PY+AS+ E++P+ T V +AT S Sbjct: 235 AKAKDGGSPALEATVDVFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATATKS-- 292 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 G ++ I YSL + + + + + F I+ +G + + LDRE Y L V G Sbjct: 293 GSSSGIAYSL---VGGQ-IENGNTMFSID-SSGRVLLLRQLDRERTKSYKLYVRGTYTG- 346 Query: 559 PSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQVGATDADVGLNG 614 SL+ TDVE ++V DVNDN P+F + D A T ++ + A D+D G N Sbjct: 347 GSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANA 406 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 ++ + ID S V++T L +V + + A D G+PPQ S + V Sbjct: 407 QVTMSIQGTVPSNAPITIDTPSNVLKTTTKL--STVIDYQITVRATDKGSPPQYSEITVI 464 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 +K+ +I +PPVF T + EN+ +G + ++A D N ++ YS G+ ++ Sbjct: 465 VKVLNI-QTPPVFGQAKYTVDVQENTKVGQQVISVKATYGDS--NGLLQYSFVSGNLGDA 521 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794 F +++ ++ LD E Y L +R A + V + +TD+ND++P Sbjct: 522 FCIDS-----SGQITVAQPLDRE-VLPSYTLRVRVALGNNEDFTEVFVSLTDINDDSPTF 575 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGN---NANLILLNETTGSM 849 F +D G+V A D D ++ YR L + + + L++TTG + Sbjct: 576 TKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGII 635 Query: 850 TLSPQLNTNVPKLATMEVSV---TDGVNEIKAMMQLSVRL 886 +L+ + + ++ + V +G N++ A+ ++ + L Sbjct: 636 SLASGKSLDYEDISMHVLFVRAEDNGANKLSAIAEVRIYL 675 Score = 112 bits (269), Expect = 4e-24 Identities = 120/458 (26%), Positives = 188/458 (41%), Gaps = 35/458 (7%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 I V QP Q RY L + D G S + PVF + YT +V E A Sbjct: 1136 IEVGQPR--LQTSRYGLDIIPFDYGKPSVNGTKATVDIETVQSPPVFNESSYTFTVSERA 1193 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P T + V+A A+++Y++ + + D G I N LLD E Sbjct: 1194 PTMTKIGDVTAVSVS---GARLSYTIIEGNTGDKFLAKDN--------GDIVLNSLLDFE 1242 Query: 543 T-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 S + L V A++ LS DV I+V++ ND P F +Y + E VG + Sbjct: 1243 RDQSVFNLKVEAKEQIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIM 1302 Query: 602 QVGATDADVGLN-----GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 V A D D + G++ Y ++ SF ID +G I + LD E+ LK Sbjct: 1303 TVTARDCDCPSDCTCPVGQLKYSVEAGT----SFDIDQ-TGAIVVARTLDYETSKVQVLK 1357 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +A D G ++ V + +ED ND+ PVF+ + F ++ ++ G+ IG + A D D+ Sbjct: 1358 VMASDQGEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQ 1417 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 V YS+ G + F++ T G L DL + +Y + IRA N Sbjct: 1418 DDIEKVRYSVVSGTE---FNVNTETGV----LTVAKDLS-TGAKSEYSMEIRATDSTKSN 1469 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSG 834 D RV + V N P ++ V A D D +++Y+I+ Sbjct: 1470 DARVRVNVEYKNMYRPEFTKCGKA-TIQENLLKGQLIATVTATDRDQGRNGEVEYKIVPV 1528 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + +N TG + + L+ T+ ++ DG Sbjct: 1529 GGQDFFTINNKTGEVITTSSLDRETKATYTVIITAEDG 1566 Score = 41.1 bits (92), Expect = 0.012 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE-LV 65 I +I VLD ND++P F M V + +G T L+A D D G N + + +E + Sbjct: 1065 IDVEITVLDENDNAPFFTMISTLGRVNSNSRAGATAFQLQARDLDSGSNGLIGFQLENIP 1124 Query: 66 TADTLNP 72 T +NP Sbjct: 1125 TLFMINP 1131 Score = 35.9 bits (79), Expect = 0.47 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 3/90 (3%) Query: 1461 GKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLS 1520 G + IGG++T + F GCI+++ L P N +GC C + Sbjct: 3007 GPLQIGGVETDLTFIGITTTGFRGCIRNIIDTEKMYDLRNPIKVVNAPEGCTLAGTCP-N 3065 Query: 1521 ICPPYSKCVTSW--DSSTCTCEAGRVGPQC 1548 C C S S C C+ G G C Sbjct: 3066 NCNDKGYCEPSLMAGKSMCVCDFGYTGRAC 3095 Score = 34.7 bits (76), Expect = 1.1 Identities = 26/74 (35%), Positives = 29/74 (39%), Gaps = 9/74 (12%) Query: 1479 VGFFEGCIQDVRIGTAQSLLNRPTV---RENVRDGCQSRADCMLSICPPYSKCVTSWDSS 1535 +G EGC R SL + P V R+NVR GC C C CV Sbjct: 3539 IGDMEGCTATNRF-QGVSLEDSPDVEVRRQNVRKGCP----CAEGFCENGGTCVDG-TPP 3592 Query: 1536 TCTCEAGRVGPQCV 1549 C C G GP CV Sbjct: 3593 YCLCSPGWTGPTCV 3606 >SB_46477| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 6116 Score = 351 bits (864), Expect = 4e-96 Identities = 236/739 (31%), Positives = 360/739 (48%), Gaps = 43/739 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V N+H+PVF+ Y S+ E A+ G+ V A+D D G + +EY VT+ Sbjct: 4867 VHVTAENEHTPVFQFMNYSVSISEWAAVGSPVFDANASDADTGIHGNLEY---YVTSGLN 4923 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D F ID SG + +SLDRE Y + + D+ + +R Sbjct: 4924 GGVD---------------FTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERR 4968 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++ + + + D+NDN P F+++ YT ++ E+++ +A++ TD D+G N+ Y+ Sbjct: 4969 AAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMA--SGASVARVATTDRDIGINANHTYS 5026 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GG+ +FSI +G ++ + LDYE +Y L I A+D GSP + I + D Sbjct: 5027 ITGGDGLGKFSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDT 5086 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F +L+ S+SE G ++ V A D D G+NAE+TY++ D + T Sbjct: 5087 NDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSVNST 5146 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 G + T LDRE A Y LLV A+D G PP++ T F Sbjct: 5147 -----GMIRTIATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSA 5201 Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + + ED P G + ++A+DAD DN RL Y I GNT +I S G L +V Sbjct: 5202 FSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGNTDNVVAIESATG-ALYSVG-A 5259 Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 D ++ Y L + A D+G T I I D N+ P F +A Y V E+ P G Sbjct: 5260 FDRERTATYTLAIRAIDAGNPPLFSTITAHIVIIDRNDNTPTFLDADYNFVVTENQPGGL 5319 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 ++ V A D D G +AQ+ Y++ + + F +NP TG + T LDRE + Sbjct: 5320 SIGHVRAIDIDNGTHAQLVYTIEP-------SPNSNHFTMNPITGGLFTAMALDRENVPY 5372 Query: 547 YLLTVTARDGGV-PS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y LTV D PS L +TT V I+V+D+NDN P F + ++ A+I E++ G SV++V Sbjct: 5373 YRLTVRVTDSAAYPSQLFNTTTVHITVLDLNDNPPAFDKAVFNASIAENSESGASVTRVT 5432 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A+D D N R+ Y L F +D A+G + +D E+V ++ A D G Sbjct: 5433 ASDRDRDANARLTYSLTYNASSPEYFRLDEATGEVFLKSGVDYENVQIIEVTVTAKDDGF 5492 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG-TTIGEIRAHDPDEGPNAVVH 723 P S + + + + D+ND+ PVF + I + +G I + A D D GPN+ V Sbjct: 5493 PSLSGSTTLRVHVIDLNDNAPVFSATFYETEIRSDHNLGPPAIITLTAIDRDSGPNSAVT 5552 Query: 724 YSIKGGDDSNSFSLETRQG 742 Y ++ F L+T G Sbjct: 5553 YELE--QTQEKFKLDTNSG 5569 Score = 349 bits (857), Expect = 3e-95 Identities = 249/762 (32%), Positives = 365/762 (47%), Gaps = 39/762 (5%) Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201 D ++ +F Y+ + E + I + +D D+G NS + Y II GNT +F Sbjct: 4768 DISEGKGEFVPALYSADISE--ATAAETAIINVTCSDTDLGPNSQLSYEIIRGNTGNKFR 4825 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 +D+ + V + LD++ + Y L +R D G SR + +++ N++ P F Sbjct: 4826 LDNHT--VVVAGQLDHDTTKDYSLEVRVSDNGVTSRVTVAVVTVHVTAENEHTPVFQFMN 4883 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + S+SE +G + A DAD G++ L Y +T G VD TID SG V Sbjct: 4884 YSVSISEWAAVGSPVFDANASDADTGIHGNLEYYVT-SGLNGGVD--FTIDKSSGVVAVG 4940 Query: 322 GQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 LDRET+ Y+L +T D G+ R+A F Y + E+ Sbjct: 4941 SSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTTIPEN 5000 Query: 379 EPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 G V + TD D N H Y ITGG+ G+FSI G+IT LD++ + Sbjct: 5001 MASGASVARVATTDRDIGINANHTYSITGGDGLGKFSIVQST--GVITALPGLDYETKYT 5058 Query: 437 YVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 Y L+++A D G A V+I ++D N+ PVF Y S+ E GT V+ V AT Sbjct: 5059 YYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHAT 5118 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D GINA+ITYS+ + +A QF +N TG I T LDRE ++ Y L V A Sbjct: 5119 DVDTGINAEITYSI---VGGDA----KNQFSVN-STGMIRTIATLDREDIASYTLLVQAS 5170 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 D GVP ++T V ++++DVNDN VF Q ++A ++EDA VG + A+DAD G N Sbjct: 5171 DRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADSGDNA 5230 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 R+ Y + + I+ A+G + + A DRE AT+ L AID G PP ST+ H Sbjct: 5231 RLTYSIQ-SGNTDNVVAIESATGALYSVGAFDRERTATYTLAIRAIDAGNPPLFSTITAH 5289 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 I I D ND+ P F F ++EN P G +IG +RA D D G +A + Y+I+ +SN Sbjct: 5290 IVIIDRNDNTPTFLDADYNFVVTENQPGGLSIGHVRAIDIDNGTHAQLVYTIEPSPNSNH 5349 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIR----AASP-PLWNDVRVEILVTDVND 789 F++ G L T + LD E+ Y L +R AA P L+N V I V D+ND Sbjct: 5350 FTMNPITGG----LFTAMALDRENV-PYYRLTVRVTDSAAYPSQLFNTTTVHITVLDLND 5404 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRI-LSGNNANLILLNETT 846 N P + ++ RV A D D +L Y + + ++ L+E T Sbjct: 5405 NPPAFDKAVFNASIAENSESGASVTRVTASDRDRDANARLTYSLTYNASSPEYFRLDEAT 5464 Query: 847 GSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 G + L ++ NV + + DG + L V +I Sbjct: 5465 GEVFLKSGVDYENVQIIEVTVTAKDDGFPSLSGSTTLRVHVI 5506 Score = 347 bits (852), Expect = 1e-94 Identities = 274/918 (29%), Positives = 435/918 (47%), Gaps = 107/918 (11%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + V N+++P F +Y ++ E GTTV+ + A+D D G E+ Y++ Sbjct: 3425 HVDVIVQALNEYTPSFSQSEYNVTISEATPIGTTVIDIDASDNDSGPQGELTYSM----- 3479 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 P + F ID SG + + LD E V Y +LV ATD S Sbjct: 3480 ----PSGSP-------------FYIDSLSGVITLKQGLDYEAVTSYVLLVTATD--GDAS 3520 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 SS + V + D+NDN P F+ Y+V + E+ +V + I + TD+D G N Sbjct: 3521 SPKSSMVNVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTS--ILSLTCTDSDSGTNGQF 3578 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLIN 246 + AII GNT F+I +G +++ LD E +Y LV+RA+D + S + +T + + Sbjct: 3579 KMAIISGNTGTGFAISD-AGVLTVATALDVETTGAYSLVVRARDQHALSPQESTAAVSVI 3637 Query: 247 IRDVNDNAPRFYTS-LFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTGN 304 I DVN++ P+F + + ++E+ P+G + V A D D G V +TYT+T +GN Sbjct: 3638 ITDVNEHTPQFTSGGSYTAVIAEDAPVGSFVTNVTAIDNDLGLVYGVVTYTIT----SGN 3693 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXX 362 + I P G ++ LDRE+ Y L++TA+D DP P+S+TAT Sbjct: 3694 SEDKFYIRPSDGSIFVKKGLDRESTPSYSLVITASDQ-DPVSPKSSTATLIVTISDVNDN 3752 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSITSQNGR 420 P Y L E GT V L +D D + Y I+ GNT S+ +G Sbjct: 3753 DPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAISSGNT----SLFGVSGN 3808 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTAS 477 GL+T D++ + Y+L V+ TD G RS + + IT AN Y P F Y+ + Sbjct: 3809 GLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGANEYEPAFSQPTYSVT 3868 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 ED IG T+ V+ATD+D G + I++++ + NE + +F+I+ +G I + Sbjct: 3869 HQEDTAIGVTIATVAATDADHGSDGAISFAIIA--GNE-----EDKFLIDTTSGVIELKR 3921 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE+ Y+LTV ARD G P+ S V+++VVDVNDN P + + E+A VG Sbjct: 3922 PLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVEVAENASVG 3981 Query: 598 TSVSQVGATDADVGLNGRIHYEL--DPKDREEG------------------SFVIDPASG 637 ++V ++ D D G N ++ Y + D D +G F ++ +SG Sbjct: 3982 STVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGNTNSDFTLNSSSG 4041 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 V+ L+RES +DL D GTPP ++ + H ED++ Sbjct: 4042 VLTVASQLNRESTVYYDLTVTITDSGTPPLTTLHLQHSLSEDVS---------------- 4085 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 +GTT+ A D D+G + V Y+I G+ +++F L+ GS L + LDYE Sbjct: 4086 ----LGTTVFIAHAQDYDDGEHGHVTYAILSGNTADTFLLDKYSGS----LQLLRSLDYE 4137 Query: 758 SPRKKYELVIRAA-----SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP 812 Y+L+I A+ S + + V I V D+NDN P + + + Sbjct: 4138 -VASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKPECSETTKHVSLLESVVVGTV 4196 Query: 813 FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 D+D +D L Y+IL+GN + + G +TL+ L+ + + V+V Sbjct: 4197 IFSTNCSDSDSSDNALLTYQILTGNAEGKFNVT-SGGEVTLASGLSVEMTSWYHLVVAVR 4255 Query: 871 DGVNEIKAM-MQLSVRLI 887 D + +A+ + L+V ++ Sbjct: 4256 DAGSPSRAVNVSLTVEVL 4273 Score = 345 bits (847), Expect = 4e-94 Identities = 270/934 (28%), Positives = 438/934 (46%), Gaps = 89/934 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V+ N+H+PVF Y S+ E + GT++L + ATD D G V Y++ + A Sbjct: 3295 IDVIAVNEHAPVFTSASYAQSIAEDTAIGTSILMVTATDGDNGPQGHVVYSLLPLNAP-- 3352 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ID SG + ++SLDRE A YT+ V A D+ +D Sbjct: 3353 -------------------FYIDTISGIIRVKSSLDRETTASYTLTVSAHDKDPVTADVK 3393 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSV---------------------DEDISVTD-N 168 ++ T+ V++ D NDN P FS YT+ + ++++++ Sbjct: 3394 TANVTVSVDVTDVNDNEPAFSPAHYTLMAVSHVDVIVQALNEYTPSFSQSEYNVTISEAT 3453 Query: 169 PV---IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL 225 P+ + I A+D D G + Y++ G+ F IDSLSG ++L + LDYE V SY L Sbjct: 3454 PIGTTVIDIDASDNDSGPQGELTYSMPSGS---PFYIDSLSGVITLKQGLDYEAVTSYVL 3510 Query: 226 VIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 ++ A DG + S +S+ + + ++D NDN P F +++ + EN +G SI+ + D+ Sbjct: 3511 LVTATDGDASSPKSSMVNVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDS 3570 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGD 343 D G N + + +GN I +G + + LD ET Y L+V A D Sbjct: 3571 DSGTNGQFKMAI----ISGNTGTGFAISD-AGVLTVATALDVETTGAYSLVVRARDQHAL 3625 Query: 344 PPRSATATXXXXXXXXXXXXXXFMP-GQYEVELAEDEPPGTPVVTLTATDADED---NRL 399 P+ +TA F G Y +AED P G+ V +TA D D + Sbjct: 3626 SPQESTAAVSVIITDVNEHTPQFTSGGSYTAVIAEDAPVGSFVTNVTAIDNDLGLVYGVV 3685 Query: 400 HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS---GGRSDTAMVQ 456 Y IT GN+ +F I +G I V + LD + Y L ++A+D +S TA + Sbjct: 3686 TYTITSGNSEDKFYIRPSDGS--IFVKKGLDRESTPSYSLVITASDQDPVSPKSSTATLI 3743 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 + I+D N+ PV + Y+ S+ E IGT+V ++ +D D+ N +Y++SS N + Sbjct: 3744 VTISDVNDNDPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAISS--GNTS 3801 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-VPSLSDTTDVEISVVDVN 575 + F ++ G +TT L D ET+ Y+L VT DGG V S + + + N Sbjct: 3802 L------FGVS-GNGLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGAN 3854 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 + EP F Q Y+ ED +G +++ V ATDAD G +G I + + EE F+ID Sbjct: 3855 EYEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAI-IAGNEEDKFLIDTT 3913 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 SGVI + LDRES ++ L +A D G+P +SS V + + D+ND+ P Sbjct: 3914 SGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVE 3973 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 ++EN+ +G+T+ E+R D DEG N+ + Y+I D + + + + + D Sbjct: 3974 VAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGNTNSD 4033 Query: 756 YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--- 812 + L + A+ + V ++ VT + P + + + +D +G Sbjct: 4034 FTLNSSSGVLTV-ASQLNRESTVYYDLTVTITDSGTPPLTTLHLQHSLSED-VSLGTTVF 4091 Query: 813 FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 YD + Y ILSGN A+ LL++ +GS+ L L+ V + + +DG Sbjct: 4092 IAHAQDYDDGEHGHVTYAILSGNTADTFLLDKYSGSLQLLRSLDYEVASSYKLIIEASDG 4151 Query: 873 VNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906 ++SVR + + +N + LND E Sbjct: 4152 A-------EVSVRK-SSRITVNIAVIDLNDNKPE 4177 Score = 338 bits (830), Expect = 5e-92 Identities = 242/793 (30%), Positives = 379/793 (47%), Gaps = 60/793 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ++ F Y A + E ++ T ++ + +D D+G N+++ Y E++ +T N Sbjct: 4768 DISEGKGEFVPALYSADISEATAAETAIINVTCSDTDLGPNSQLSY--EIIRGNTGNK-- 4823 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 FR+D + ++ LD + Y++ V+ +D V+ R++ A Sbjct: 4824 ---------------FRLDNHT--VVVAGQLDHDTTKDYSLEVRVSDNG--VTSRVT-VA 4863 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + V++ +N++ P F Y+VS+ E +V +PV A+DAD G + + Y + G Sbjct: 4864 VVTVHVTAENEHTPVFQFMNYSVSISEWAAV-GSPVF-DANASDADTGIHGNLEYYVTSG 4921 Query: 195 -NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS---RSNTTQLLINIRDV 250 N + F+ID SG V++ +LD E Y L I +D G+ R+ QL I + D Sbjct: 4922 LNGGVDFTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDE 4981 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F ++ ++ EN+ G S+ RV D D G+NA TY++T D G + Sbjct: 4982 NDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINANHTYSITGGDGLGK----FS 5037 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I +G + LD ET+ Y L +TA D G P A A F P Sbjct: 5038 IVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTL 5097 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y ++E GT V+ + ATD D + + Y I GG+ + +FS+ N G+I Sbjct: 5098 YLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSV---NSTGMIRTIAT 5154 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y L V A+D G +++T V + I D N+ A VF + ++A V EDAP+G Sbjct: 5155 LDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGF 5214 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + +SA+D+D G NA++TYS+ S ++ VA I TGA+ + DRE + Sbjct: 5215 RFMNISASDADSGDNARLTYSIQSGNTDNVVA-------IESATGALYSVGAFDRERTAT 5267 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y L + A D G P L T I ++D NDN P F Y + E+ G S+ V A Sbjct: 5268 YTLAIRAIDAGNPPLFSTITAHIVIIDRNDNTPTFLDADYNFVVTENQPGGLSIGHVRAI 5327 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G + ++ Y ++P F ++P +G + T ALDRE+V + L D P Sbjct: 5328 DIDNGTHAQLVYTIEPSP-NSNHFTMNPITGGLFTAMALDRENVPYYRLTVRVTDSAAYP 5386 Query: 667 QS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 +T VHI + D+ND+PP F+ I+ENS G ++ + A D D NA + Y Sbjct: 5387 SQLFNTTTVHITVLDLNDNPPAFDKAVFNASIAENSESGASVTRVTASDRDRDANARLTY 5446 Query: 725 SIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRV 780 S+ F L+ G E+ +DYE+ + E+ + A P L + Sbjct: 5447 SLTYNASSPEYFRLDEATG----EVFLKSGVDYENV-QIIEVTVTAKDDGFPSLSGSTTL 5501 Query: 781 EILVTDVNDNAPV 793 + V D+NDNAPV Sbjct: 5502 RVHVIDLNDNAPV 5514 Score = 332 bits (815), Expect = 3e-90 Identities = 258/827 (31%), Positives = 393/827 (47%), Gaps = 102/827 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+SPV Y ASV E + G++VLT+ D DIG N EV Y++ V+ D Sbjct: 2772 IAISDVNDNSPVCSQAMYTASVLESVAVGSSVLTVSCPDLDIGANGEVSYSV--VSGDG- 2828 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ++ +G L T + L+ E RYT+ ++A+D +P + Sbjct: 2829 -----------------GAFALNSSTGILSTTSPLNYETTMRYTLSIQASDGGTP--GKA 2869 Query: 131 SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+T + +++ N+ P F TY +S+ ED+SV + ++ + A+DAD G+ + Y Sbjct: 2870 STTLAV-IDVQGVNEYTPSFIPNNTYELSLAEDLSVGHDVIL--VTASDADAGSQGEVTY 2926 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIR 248 +I G+T F+ID G + L LDYE + L+I A DG S S T L IN+ Sbjct: 2927 SITSGDTYGNFAIDRARGLIELRSMLDYELISQIVLIIAATDGDPLSPNSATASLTINVV 2986 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P +L +V E+ +G + + D D G+N +LTYT + GN ++ Sbjct: 2987 DVNDNYPSCNPALLTPAVPESAAVGSMLASLNCSDTDSGLNGQLTYTFVSGNTAGNFNVS 3046 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +G V + LD E+ Y L+++ TD G +S + F Sbjct: 3047 T-----AGVVSLATALDYESTRLYSLVLSVTDSGPSTKSTQVSIKVTVIAVNEFSPVFTS 3101 Query: 369 G-QYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRFSITSQNGRGLI 423 G Y V ++E GT ++ +TA DAD + H Y I GNT F + + G + Sbjct: 3102 GGTYAVTVSEHTSLGTELIRVTANDADLNTHAHGMITYSIISGNTGSHFYVATDTGAIHL 3161 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 K +R + S T G + A V + I+D N+ P Y A+V EDA Sbjct: 3162 -------MKGDRSVIFAHSTTTDGENNVNATVALTISDVNDNDPACSPTSYAATVREDAG 3214 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 +GT+++ V DSD G N + +S+++ +N F I+ G I+T + LD ET Sbjct: 3215 LGTSLVRVLCLDSDEGNNGLLAFSITAGNTNT-------DFTIDAN-GTISTARALDYET 3266 Query: 544 MSGYLLTVTARDGGVPSLSDTT---DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 + Y LTV +RD P S + +V I V+ VN++ PVF Y +I ED +GTS+ Sbjct: 3267 TTSYTLTVKSRDSSSPISSQRSVNVEVTIDVIAVNEHAPVFTSASYAQSIAEDTAIGTSI 3326 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V ATD D G G + Y L P + F ID SG+IR +LDRE+ A++ L A Sbjct: 3327 LMVTATDGDNGPQGHVVYSLLPLN---APFYIDTISGIIRVKSSLDRETTASYTLTVSAH 3383 Query: 661 DGG---TPPQSSTVIVHIKIEDINDSPPVFES-----------DCLTFYISENSP----- 701 D +++ V V + + D+ND+ P F D + ++E +P Sbjct: 3384 DKDPVTADVKTANVTVSVDVTDVNDNEPAFSPAHYTLMAVSHVDVIVQALNEYTPSFSQS 3443 Query: 702 -----------IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 IGTT+ +I A D D GP + YS+ G + F +++ G ++T Sbjct: 3444 EYNVTISEATPIGTTVIDIDASDNDSGPQGELTYSMPSG---SPFYIDSLSG-----VIT 3495 Query: 751 MVD-LDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAP 792 + LDYE+ Y L++ A AS P + V V + V D NDN P Sbjct: 3496 LKQGLDYEAV-TSYVLLVTATDGDASSPKSSMVNVTVTVKDENDNEP 3541 Score = 327 bits (804), Expect = 7e-89 Identities = 265/884 (29%), Positives = 415/884 (46%), Gaps = 80/884 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND P F Y S+RE ++GT VL A D+D G DTL Sbjct: 2377 VNVLDVNDE-PQFINSPYSVSIRENLATGTRVLQASAADEDTG--------------DTL 2421 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I +G + T + +D E V+ Y++ V +D VS+ Sbjct: 2422 TYSLSGSNHAH--------FSISN-TGVISTASGIDFEVVSSYSLSVAVSDGTVSVSE-- 2470 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + +++ + ND+ P F++ Y +++E+ S + I ++ TD D + +I ++ Sbjct: 2471 ----PVMISVENLNDS-PVFTDAPYNATINENTSTATS--ILQVSTTDQD---SDSITFS 2520 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 +G T F+I S SG ++ ++YE+ +Y L I+A DG T I + D+ Sbjct: 2521 FVGV-TSSDFNIHSSSGIITTAVNINYEKTAAYTLTIQADDGNGGKTLTTAS--ITVTDL 2577 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND P F ++ + V EN G S++ V A D D ++ L Y+++ + +T Sbjct: 2578 NDERPTFASASYTGHVVENAASGTSVIVVTATDLDVA-DSTLAYSLSG---ASSSHFNVT 2633 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 + G + T+ +D E+ Y L +TA+DG + T T F Sbjct: 2634 SE---GLISTAAAIDYESLTSYSLTLTASDGAG--NTGTTTINIAVVNVIDNDPVFGSVS 2688 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y ED GT V +TATDAD + + Y ++G + F+I G +I+ D Sbjct: 2689 YSANAFEDSVAGTSVTRITATDADIGDVITYSLSGPESTN-FTINVNTG--VISTNSAFD 2745 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + + Y T++ATD+G R DTA+V I I+D N+ +PV A YTASV E +G++VL Sbjct: 2746 RESKDTYTFTITATDTGSRPDTAIVTIAISDVNDNSPVCSQAMYTASVLESVAVGSSVLT 2805 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 VS D D+G N +++YS+ +S + A F +N TG ++T L+ ET Y L+ Sbjct: 2806 VSCPDLDIGANGEVSYSV---VSGDGGA-----FALNSSTGILSTTSPLNYETTMRYTLS 2857 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVSQVGATDAD 609 + A DGG P + TT I V VN+ P F Y ++ ED VG V V A+DAD Sbjct: 2858 IQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVGHDVILVTASDAD 2917 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-TPPQS 668 G G + Y + D G+F ID A G+I LD E ++ L A DG P S Sbjct: 2918 AGSQGEVTYSITSGD-TYGNFAIDRARGLIELRSMLDYELISQIVLIIAATDGDPLSPNS 2976 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 +T + I + D+ND+ P LT + E++ +G+ + + D D G N + Y+ Sbjct: 2977 ATASLTINVVDVNDNYPSCNPALLTPAVPESAAVGSMLASLNCSDTDSGLNGQLTYTFVS 3036 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVT-- 785 G+ + +F++ T + L T LDYES R Y LV+ S P +V I VT Sbjct: 3037 GNTAGNFNVST---AGVVSLATA--LDYESTR-LYSLVLSVTDSGPSTKSTQVSIKVTVI 3090 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT----DKLQYRILSGNNANLI 840 VN+ +PV + +G RV A DAD+ + Y I+SGN + Sbjct: 3091 AVNEFSPVFTSGGTYAVTVSEHTSLGTELIRVTANDADLNTHAHGMITYSIISGNTGSHF 3150 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + TG++ L + + +T TDG N + A + L++ Sbjct: 3151 YVATDTGAIHLMKGDRSVIFAHST----TTDGENNVNATVALTI 3190 Score = 323 bits (793), Expect = 1e-87 Identities = 251/801 (31%), Positives = 398/801 (49%), Gaps = 80/801 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V++ D+ PVF Y A+ E + +GT+V + ATD DIG +++T Sbjct: 2672 IAVVNVIDNDPVFGSVSYSANAFEDSVAGTSVTRITATDADIG---------DVITYSLS 2722 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE F I+ +G + T ++ DRE YT + ATD S Sbjct: 2723 GPESTN-------------FTINVNTGVISTNSAFDRESKDTYTFTITATDTGSR----- 2764 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 TA + + I D NDN P S+ YT SV E ++V + + + D D+GAN + Y+ Sbjct: 2765 PDTAIVTIAISDVNDNSPVCSQAMYTASVLESVAVGSS--VLTVSCPDLDIGANGEVSYS 2822 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 ++ G+ F+++S +G +S L+YE Y L I+A DGG+P +++TT +I+++ V Sbjct: 2823 VVSGDGGA-FALNSSTGILSTTSPLNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGV 2881 Query: 251 NDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N+ P F + ++ S++E++ +G+ ++ V A DAD G E+TY++T D GN Sbjct: 2882 NEYTPSFIPNNTYELSLAEDLSVGHDVILVTASDADAGSQGEVTYSITSGDTYGN----F 2937 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXFM 367 ID G + LD E ++ L++ ATDG DP P SATA+ Sbjct: 2938 AIDRARGLIELRSMLDYELISQIVLIIAATDG-DPLSPNSATASLTINVVDVNDNYPSCN 2996 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 P + E G+ + +L +D D + +L Y GNT G F++++ G++++ Sbjct: 2997 PALLTPAVPESAAVGSMLASLNCSDTDSGLNGQLTYTFVSGNTAGNFNVSTA---GVVSL 3053 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENA-PYTASVFEDA 482 A LD++ R Y L +S TDSG + + V I +T N ++PVF + Y +V E Sbjct: 3054 ATALDYESTRLYSLVLSVTDSGPSTKSTQVSIKVTVIAVNEFSPVFTSGGTYAVTVSEHT 3113 Query: 483 PIGTTVLVVSATDSDVGINAQ--ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +GT ++ V+A D+D+ +A ITYS+ IS +H F + TGAI K D Sbjct: 3114 SLGTELIRVTANDADLNTHAHGMITYSI---ISGNTGSH----FYVATDTGAIHLMKG-D 3165 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 R + + T G +++ T V +++ DVNDN+P Y A + EDA +GTS+ Sbjct: 3166 RSVIFAHSTTTD----GENNVNAT--VALTISDVNDNDPACSPTSYAATVREDAGLGTSL 3219 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +V D+D G NG + + + + F ID A+G I T +ALD E+ ++ L + Sbjct: 3220 VRVLCLDSDEGNNGLLAFSITAGNTNT-DFTID-ANGTISTARALDYETTTSYTLTVKSR 3277 Query: 661 DGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 D +P +S V V I + +N+ PVF S I+E++ IGT+I + A D D G Sbjct: 3278 DSSSPISSQRSVNVEVTIDVIAVNEHAPVFTSASYAQSIAEDTAIGTSILMVTATDGDNG 3337 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-ASPPLWN 776 P V YS+ + F ++T G + + LD E+ Y L + A P+ Sbjct: 3338 PQGHVVYSLL--PLNAPFYIDTISGIIRVK----SSLDRET-TASYTLTVSAHDKDPVTA 3390 Query: 777 DVR-----VEILVTDVNDNAP 792 DV+ V + VTDVNDN P Sbjct: 3391 DVKTANVTVSVDVTDVNDNEP 3411 Score = 291 bits (714), Expect = 5e-78 Identities = 235/798 (29%), Positives = 383/798 (47%), Gaps = 78/798 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND P F Y V E A+SGT+V+ + ATD D+ ++ + Y++ ++ Sbjct: 2572 ITVTDLNDERPTFASASYTGHVVENAASGTSVIVVTATDLDVA-DSTLAYSLSGASSSHF 2630 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N G + T A++D E + Y++ + A+D A Sbjct: 2631 NVTS---------------------EGLISTAAAIDYESLTSYSLTLTASDGAGN----- 2664 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T TI++ +++ DN P F +Y+ + ED SV V +I ATDAD+G I Y+ Sbjct: 2665 TGTTTINIAVVNVIDNDPVFGSVSYSANAFED-SVAGTSV-TRITATDADIG--DVITYS 2720 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G + F+I+ +G +S D E +Y I A D GS R +T + I I DV Sbjct: 2721 LSGPEST-NFTINVNTGVISTNSAFDRESKDTYTFTITATDTGS--RPDTAIVTIAISDV 2777 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN+P +++ SV E+V +G S++ V D D G N E++Y++ D G Sbjct: 2778 NDNSPVCSQAMYTASVLESVAVGSSVLTVSCPDLDIGANGEVSYSVVSGD--GGA---FA 2832 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ++ +G + T+ L+ ET +Y L + A+DGG P +++T F+P Sbjct: 2833 LNSSTGILSTTSPLNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNN 2892 Query: 371 -YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427 YE+ LAED G V+ +TA+DAD ++ + Y IT G+T G F+I RGLI + Sbjct: 2893 TYELSLAEDLSVGHDVILVTASDADAGSQGEVTYSITSGDTYGNFAI--DRARGLIELRS 2950 Query: 428 PLDFKQERRYVLTVSATDS---GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 LD++ + VL ++ATD S TA + IN+ D N+ P A T +V E A + Sbjct: 2951 MLDYELISQIVLIIAATDGDPLSPNSATASLTINVVDVNDNYPSCNPALLTPAVPESAAV 3010 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G+ + ++ +D+D G+N Q+TY+ S N A F ++ G ++ LD E+ Sbjct: 3011 GSMLASLNCSDTDSGLNGQLTYTFVS--GNTA-----GNFNVST-AGVVSLATALDYEST 3062 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-LYTANIMEDALVGTSVSQV 603 Y L ++ D G + S ++++V+ VN+ PVF Y + E +GT + +V Sbjct: 3063 RLYSLVLSVTDSGPSTKSTQVSIKVTVIAVNEFSPVFTSGGTYAVTVSEHTSLGTELIRV 3122 Query: 604 GATDADVGLN--GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 A DAD+ + G I Y + F + +G I K DR + H + D Sbjct: 3123 TANDADLNTHAHGMITYSII-SGNTGSHFYVATDTGAIHLMKG-DRSVIFAH---STTTD 3177 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G + V + I D+ND+ P + E++ +GT++ + D DEG N + Sbjct: 3178 G---ENNVNATVALTISDVNDNDPACSPTSYAATVREDAGLGTSLVRVLCLDSDEGNNGL 3234 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPPLWN--- 776 + +SI G+ + F+++ + T LDYE+ Y L + R +S P+ + Sbjct: 3235 LAFSITAGNTNTDFTIDA-----NGTISTARALDYET-TTSYTLTVKSRDSSSPISSQRS 3288 Query: 777 -DVRVEILVTDVNDNAPV 793 +V V I V VN++APV Sbjct: 3289 VNVEVTIDVIAVNEHAPV 3306 Score = 282 bits (692), Expect = 2e-75 Identities = 248/894 (27%), Positives = 409/894 (45%), Gaps = 86/894 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ + V D ND+ P F Y + E + GT++L+L TD D G N ++ + +++ Sbjct: 3527 VNVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTNG--QFKMAIIS 3584 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 +T + D +G L +LD E Y+++V+A DQ + + Sbjct: 3585 GNT-----------GTGFAISD-------AGVLTVATALDVETTGAYSLVVRARDQHA-L 3625 Query: 127 SDRLSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVG-AN 184 S + STA + V I D N++ PQF S +YT + ED V + + A D D+G Sbjct: 3626 SPQ-ESTAAVSVIITDVNEHTPQFTSGGSYTAVIAEDAPV--GSFVTNVTAIDNDLGLVY 3682 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA--QDGGSPSRSNTTQ 242 + Y I GN++ +F I G + + K LD E SY LVI A QD SP +S+T Sbjct: 3683 GVVTYTITSGNSEDKFYIRPSDGSIFVKKGLDRESTPSYSLVITASDQDPVSP-KSSTAT 3741 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 L++ I DVNDN P ++ +S+ E+V IG S+ ++ D D N +Y ++ + Sbjct: 3742 LIVTISDVNDNDPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAIS----S 3797 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXX 361 GN L + +G V T G D ET Y L+VT TDGG RS Sbjct: 3798 GNTSL-FGVS-GNGLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGANE 3855 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F Y V ED G + T+ ATDAD D + + I GN +F I + + Sbjct: 3856 YEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAIIAGNEEDKFLIDTTS- 3914 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G+I + +PLD + Y+LTV A D G +S A V + + D N+ AP + Sbjct: 3915 -GVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVE 3973 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--------------ISNEAVAHHDQQ 523 V E+A +G+TVL + D D G N+Q+TY+++++ + ++ + + Sbjct: 3974 VAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGNTNSD 4033 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F +N +G +T L+RE+ Y LTVT D G P L+ T ++ S Sbjct: 4034 FTLNSSSGVLTVASQLNRESTVYYDLTVTITDSGTPPLT-TLHLQHS------------- 4079 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 + ED +GT+V A D D G +G + Y + + + +F++D SG ++ + Sbjct: 4080 ------LSEDVSLGTTVFIAHAQDYDDGEHGHVTYAILSGNTAD-TFLLDKYSGSLQLLR 4132 Query: 644 ALDRESVATHDLKAVAIDGG--TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 +LD E +++ L A DG + +SS + V+I + D+ND+ P + E+ Sbjct: 4133 SLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKPECSETTKHVSLLESVV 4192 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 +GT I D D NA++ Y I G+ F++ + + L + + ++ S Sbjct: 4193 VGTVIFSTNCSDSDSSDNALLTYQILTGNAEGKFNVTS---GGEVTLASGLSVEMTSWYH 4249 Query: 762 KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF---GRVP 817 V A SP +V + + V VN+ P +++ N + +G +V Sbjct: 4250 LVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDLYSLNVFENVTLGTIVFQAQVQ 4309 Query: 818 AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D + L++ ++SGN+ L ++G + L L+ ++ V V D Sbjct: 4310 DNDTGLHGTLRFSLVSGNDQGCFYLEPSSGMLVLVSPLDRETVDHYSVMVKVED 4363 Score = 280 bits (687), Expect = 1e-74 Identities = 260/862 (30%), Positives = 397/862 (46%), Gaps = 87/862 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D ND +PV Y A + E SSG V + A+DQD +ADT+ Sbjct: 1985 VTVVDQND-TPVLTGSPYTARIEENLSSGGVVAHVVASDQD--------------SADTM 2029 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N + F I +G + + LD E V+ YT+ V+ TD + S Sbjct: 2030 NYTLSGTNSAH--------FSISS-AGVITSARVLDYESVSAYTLGVQVTDGTATAS--- 2077 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+ V ++D ND P FS T+T V E+ + + + ATDAD G + Y Sbjct: 2078 ---TTVTVTVVDANDA-PVFSNSTFTAQVSENDA---GAAVCTVSATDADSGPADTLTYT 2130 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G ++ QFS+ + +G V+L LDYE+ + L +R DG + S T L I +++ Sbjct: 2131 LYGASSS-QFSLHASTGVVTLSNVLDYEEASQHVLTVRVSDGRGGTVS--TSLTIKVQNQ 2187 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND P F + + S+ EN+ G S+ A D D G TY+++ G T Sbjct: 2188 ND-PPVFRGTPYTTSIDENLSAGSSVFVAIATDEDNGDTC--TYSIS-----GVNSSDFT 2239 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 + +G + T LD E Y L VT TD S+ + F+ Sbjct: 2240 MASATGILTTLKVLDFEQLNSYSLTVTVTDS----TSSVSQPITITVSDVNDSPGFLDAP 2295 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y + + E+ + + T++A+D D D L Y +TG G T + GL+T+A+ L+ Sbjct: 2296 YSISVQENSINAS-LCTVSASDEDNDT-LSYSLTGS---GASYFTIHSATGLVTLAKSLN 2350 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 ++ + LTV +D G S+T+ + +N+ D N+ P F N+PY+ S+ E+ GT VL Sbjct: 2351 YEGSSMFSLTVIVSDVQGASNTSTLTVNVLDVND-EPQFINSPYSVSIRENLATGTRVLQ 2409 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 SA D D G +TYSLS SN A F I+ TG I+T +D E +S Y L+ Sbjct: 2410 ASAADEDTG--DTLTYSLSG--SNHA------HFSIS-NTGVISTASGIDFEVVSSYSLS 2458 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 V DG V S+S+ V ISV ++ND+ PVF Y A I E+ TS+ QV TD D Sbjct: 2459 VAVSDGTV-SVSE--PVMISVENLNDS-PVFTDAPYNATINENTSTATSILQVSTTDQD- 2513 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 + I + F I +SG+I T ++ E A + L A DG +T Sbjct: 2514 --SDSITFSF--VGVTSSDFNIHSSSGIITTAVNINYEKTAAYTLTIQADDGNGGKTLTT 2569 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 I + D+ND P F S T ++ EN+ GT++ + A D D ++ + YS+ G Sbjct: 2570 --ASITVTDLNDERPTFASASYTGHVVENAASGTSVIVVTATDLDVA-DSTLAYSLSGAS 2626 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVND 789 S+ F++ T +G + T +DYES Y L + A+ + I V +V D Sbjct: 2627 SSH-FNV-TSEGL----ISTAAAIDYES-LTSYSLTLTASDGAGNTGTTTINIAVVNVID 2679 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849 N PV N ++D R+ A DAD+ D + Y LSG + +N TG + Sbjct: 2680 NDPVFGSVSYSANAFEDSVAGTSVTRITATDADIGDVITYS-LSGPESTNFTINVNTGVI 2738 Query: 850 TLSPQLNTNVPKLATMEVSVTD 871 + + + T ++ TD Sbjct: 2739 STNSAFDRESKDTYTFTITATD 2760 Score = 279 bits (685), Expect = 2e-74 Identities = 264/880 (30%), Positives = 411/880 (46%), Gaps = 97/880 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND +P+ Y AS+ E A GT V+ ATD D G DT+ Sbjct: 492 ITVTDAND-APISVSASYSASIEEDAPVGTNVIQTSATDVDSG--------------DTI 536 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + F I G +G + T SLD E + Y++ V D L Sbjct: 537 SYSLSGSAH----------FSITG-TGLIKTAESLDYETTSSYSLTVSFFDGT------L 579 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S T + +++ + ND P YT SV E V + + ATDAD + Y+ Sbjct: 580 SVTKAVSISVTNKNDA-PVLPSSPYTASVSEGSLV--GTAVYDVNATDAD---GDTLTYS 633 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G + FSI S +G V+ K LDYE V SY L IR DG T L + I + Sbjct: 634 LYGAGSS-SFSISSATGVVTTAKALDYEAVTSYTLTIRVTDGNGGITE--TSLTVTITNS 690 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND+ P+F ++ + +V EN+ G S++ V A D D G LTY+++ G + + Sbjct: 691 NDS-PQFLSTPYNTAVDENLGTGTSVISVSAIDQDSGNT--LTYSLS-----GTNNAHFS 742 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I SG V T+ LD E + Y L V+ +DG T F Sbjct: 743 ISSASGLVTTAQALDHEAVSSYSLTVSVSDG----TVTVTTALVITVTNRNDAPAFSNAP 798 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y +AE+ G+ V T++ATD D + + Y I+G + G FSI S G ++T+A+ L+ Sbjct: 799 YSASVAENNA-GSAVYTVSATDEDSGDTMTYFISGTGS-GDFSIDSSTG--VVTLARALN 854 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 ++ Y L++ D G SD+ + I +TDAN+ APVF + PY A + E IGT VL Sbjct: 855 YEDTTYYSLSILVLDGKGESDSTNLNITVTDAND-APVFLSTPYAAHISEGVAIGTNVLK 913 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 +ATD D + +TY+L+ S AH F ++ TG I+T +LDRE++S Y LT Sbjct: 914 ATATDQDT--SDTLTYALTGTNS----AH----FAVS-STGMISTAHVLDRESVSSYSLT 962 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 ++ DG + + T V I+VV+ ND PVF Y++ + E +V ATD D Sbjct: 963 LSVSDG---TANVTQGVSITVVNAND-VPVFTGAPYSSTVAEGD-AAAAVYTASATDGD- 1016 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 + + L SF ++P++GVI AL+ E+ + L A DG ++T Sbjct: 1017 --GDTLVFSLSGTGST--SFSMNPSTGVITLTAALNYETSPAYSLTIRADDGNGGVATTT 1072 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 + +I + + NDSP VF + ++EN PIGTT+ ++ A D D + YS+ G + Sbjct: 1073 L--NITVTNQNDSP-VFSGTPFSATLTENDPIGTTVLKVIAIDEDSAD--TLSYSLSGSN 1127 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790 ++ F++ GS + T LD E+ Y L + + + + + + D ND Sbjct: 1128 SAH-FAI----GSSTGVITTAQLLDRETV-NSYSLTVSVSDGTATVNQALSVTINDAND- 1180 Query: 791 APVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849 AP+ + +N + G V A DAD +D + Y I G+ ++ ++ ++G + Sbjct: 1181 APLFTNAP--YNATVNENAGSGSVYTVSATDAD-SDVIAYSIY-GHGSDKFSIHSSSGLV 1236 Query: 850 TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 TL+ ++ + V D N A L V ++ + Sbjct: 1237 TLASAVDFETKSSFVLTVQAAD-TNGAIATTSLYVDVVNQ 1275 Score = 277 bits (678), Expect = 1e-73 Identities = 220/740 (29%), Positives = 341/740 (46%), Gaps = 86/740 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ PV + Y S+ E + GT+V L +D+D+ N Y I + +T Sbjct: 3744 VTISDVNDNDPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAIS--SGNT- 3800 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F + G +G + T D E V Y ++V TD V+ R Sbjct: 3801 -----------------SLFGVSG-NGLVTTLGLFDYETVKSYILVVTVTD-GGLVTQR- 3840 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ I V I N+ P FS+ TY+V+ ED ++ IA + ATDAD G++ AI +A Sbjct: 3841 STQVAISVQITGANEYEPAFSQPTYSVTHQEDTAI--GVTIATVAATDADHGSDGAISFA 3898 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 II GN + +F ID+ SG + L + LD E SY L + A+D GSP++S+ + + + DV Sbjct: 3899 IIAGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDV 3958 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT------------- 297 NDNAP + V+EN +G +++ ++ D DEG N++LTY +T Sbjct: 3959 NDNAPNCSVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDND 4018 Query: 298 ----DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 D D GN + T++ SG + + QL+RE+ Y L VT TD G PP + Sbjct: 4019 GDAVDCDSEGNTNSDFTLNSSSGVLTVASQLNRESTVYYDLTVTITDSGTPPLTTL---- 4074 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGR 411 + L+ED GT V A D D+ H Y I GNT Sbjct: 4075 ----------------HLQHSLSEDVSLGTTVFIAHAQDYDDGEHGHVTYAILSGNTADT 4118 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAP 467 F + +G + + + LD++ Y L + A+D S +S V I + D N+ P Sbjct: 4119 FLLDKYSGS--LQLLRSLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKP 4176 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 S+ E +GT + + +DSD NA +TY + + + + +F + Sbjct: 4177 ECSETTKHVSLLESVVVGTVIFSTNCSDSDSSDNALLTYQILT-------GNAEGKFNVT 4229 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ--QL 585 G +T L E S Y L V RD G PS + + + V+ VN+ P F L Sbjct: 4230 -SGGEVTLASGLSVEMTSWYHLVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDL 4288 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 Y+ N+ E+ +GT V Q D D GL+G + + L ++G F ++P+SG++ L Sbjct: 4289 YSLNVFENVTLGTIVFQAQVQDNDTGLHGTLRFSL-VSGNDQGCFYLEPSSGMLVLVSPL 4347 Query: 646 DRESVATHDLKAVAIDGG-TPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 DRE+V + + D + P +SS V V I + D+ND+ P + ISE Sbjct: 4348 DRETVDHYSVMVKVEDSSQSDPDVRSSNVTVAITVLDVNDNDPECVPALYSADISEGK-- 4405 Query: 703 GTTIGEIRAHDPDEGPNAVV 722 G + + + D EG V Sbjct: 4406 GEFVPALYSADISEGKGEFV 4425 Score = 271 bits (664), Expect = 6e-72 Identities = 232/812 (28%), Positives = 370/812 (45%), Gaps = 91/812 (11%) Query: 13 VLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 + D N+H+P F Y A + E A G+ V + A D D+G + Y + T + N Sbjct: 3638 ITDVNEHTPQFTSGGSYTAVIAEDAPVGSFVTNVTAIDNDLG----LVYGVVTYTITSGN 3693 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 ED F I G++ + LDRE Y++++ A+DQ PVS + S Sbjct: 3694 SEDK--------------FYIRPSDGSIFVKKGLDRESTPSYSLVITASDQ-DPVSPK-S 3737 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 STAT+ V I D NDN P Y+ S+ E +++ + +A++ +D D+ N YAI Sbjct: 3738 STATLIVTISDVNDNDPVCDPVVYSKSLVESVAIGTS--VAQLACSDRDLVPNVVSSYAI 3795 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDV 250 GNT + F + +G V+ + DYE V+SY LV+ DGG + RS + + I Sbjct: 3796 SSGNTSL-FGVSG-NGLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGA 3853 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N+ P F + + E+ IG +I V A DAD G + +++ + GN + Sbjct: 3854 NEYEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAII----AGNEEDKFL 3909 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID SG + LDRE+ Y L V A D G P +S+ A+ Sbjct: 3910 IDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTA 3969 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---------------------GN 407 + VE+AE+ G+ V+ L D DE +++L Y IT GN Sbjct: 3970 HVVEVAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGN 4029 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467 T F++ S +G ++TVA L+ + Y LTV+ TDSG P Sbjct: 4030 TNSDFTLNSSSG--VLTVASQLNRESTVYYDLTVTITDSG------------------TP 4069 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 S+ ED +GTTV + A D D G + +TY++ S N A F+++ Sbjct: 4070 PLTTLHLQHSLSEDVSLGTTVFIAHAQDYDDGEHGHVTYAILS--GNTA-----DTFLLD 4122 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQL 585 +G++ + LD E S Y L + A DG S+ S V I+V+D+NDN+P + Sbjct: 4123 KYSGSLQLLRSLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKPECSETT 4182 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 +++E +VGT + +D+D N + Y++ EG F + + G + L Sbjct: 4183 KHVSLLESVVVGTVIFSTNCSDSDSSDNALLTYQI-LTGNAEGKFNVT-SGGEVTLASGL 4240 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES--DCLTFYISENSPIG 703 E + + L D G+P ++ V + +++ +N+ P F + D + + EN +G Sbjct: 4241 SVEMTSWYHLVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDLYSLNVFENVTLG 4300 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD---LDYESPR 760 T + + + D D G + + +S+ G+D F LE G LV+ +D +D+ S Sbjct: 4301 TIVFQAQVQDNDTGLHGTLRFSLVSGNDQGCFYLEPSSG--MLVLVSPLDRETVDHYSVM 4358 Query: 761 KKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 K E ++ ++V V I V DVNDN P Sbjct: 4359 VKVEDSSQSDPDVRSSNVTVAITVLDVNDNDP 4390 Score = 263 bits (645), Expect = 1e-69 Identities = 245/856 (28%), Positives = 396/856 (46%), Gaps = 94/856 (10%) Query: 18 DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77 + +P F + Y + E + +GT ++T+ A+D D G DT+ + Sbjct: 302 NEAPSFALASYSGRIHENSVNGTDIITVTASDVDSG--------------DTITYSLSGS 347 Query: 78 XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137 V + G SLD E YT+ + ATD L+ TAT+ Sbjct: 348 GSSSFSALTTGVIEVSG---------SLDFEATPTYTLTLTATDTGG-----LTDTATLT 393 Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 +++ + N++ P F+ +Y SV E+ + + + ATD DVG +++ Y++ G + Sbjct: 394 ISVDNVNES-PVFTSASYAASVAENDAAAS---VVTVAATDPDVG--NSVTYSLTGSGSS 447 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 F++ SG V L + LDYE +Y L + A DG TT L I + D ND AP Sbjct: 448 -HFTVHPTSGVVILTQALDYETKPTYSLTVAASDG--QGGLATTSLTITVTDAND-APIS 503 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 ++ + S+ E+ P+G ++++ A D D G ++Y++ +G+ IT +G Sbjct: 504 VSASYSASIEEDAPVGTNVIQTSATDVDSG--DTISYSL-----SGSAHFSIT---GTGL 553 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELA 376 + T+ LD ET + Y L V+ DG + + T +P Y ++ Sbjct: 554 IKTAESLDYETTSSYSLTVSFFDG-----TLSVTKAVSISVTNKNDAPVLPSSPYTASVS 608 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 E GT V + ATDAD D L Y + G + FSI+S G++T A+ LD++ Sbjct: 609 EGSLVGTAVYDVNATDADGDT-LTYSLYGAGS-SSFSISS--ATGVVTTAKALDYEAVTS 664 Query: 437 YVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 Y LT+ TD G + + IT++N+ +P F + PY +V E+ GT+V+ VSA D Sbjct: 665 YTLTIRVTDGNGGITETSLTVTITNSND-SPQFLSTPYNTAVDENLGTGTSVISVSAIDQ 723 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G +TYSLS +N A F I+ +G +TT + LD E +S Y LTV+ DG Sbjct: 724 DSG--NTLTYSLSG--TNNA------HFSISSASGLVTTAQALDHEAVSSYSLTVSVSDG 773 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 +++ TT + I+V + ND P F Y+A++ E+ G++V V ATD D G + Sbjct: 774 ---TVTVTTALVITVTNRND-APAFSNAPYSASVAENN-AGSAVYTVSATDEDSG--DTM 826 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y + G F ID ++GV+ +AL+ E + L + +DG +S + ++I Sbjct: 827 TYFI--SGTGSGDFSIDSSTGVVTLARALNYEDTTYYSLSILVLDG--KGESDSTNLNIT 882 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 + D ND+ PVF S +ISE IGT + ++A D+ + + Y++ G +S F+ Sbjct: 883 VTDANDA-PVFLSTPYAAHISEGVAIGTNV--LKATATDQDTSDTLTYALT-GTNSAHFA 938 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796 + S + T LD ES Y L + + V I V + ND PV Sbjct: 939 V-----SSTGMISTAHVLDRESV-SSYSLTLSVSDGTANVTQGVSITVVNAND-VPVFTG 991 Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 + + A D D D L + LSG + +N +TG +TL+ LN Sbjct: 992 AP-YSSTVAEGDAAAAVYTASATDGD-GDTLVFS-LSGTGSTSFSMNPSTGVITLTAALN 1048 Query: 857 TNVPKLATMEVSVTDG 872 ++ + DG Sbjct: 1049 YETSPAYSLTIRADDG 1064 Score = 257 bits (630), Expect = 8e-68 Identities = 234/728 (32%), Positives = 347/728 (47%), Gaps = 60/728 (8%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F Y+ +V+E++++ I ATD+D AI +II + D Sbjct: 206 PVFGSAAYSGTVNENVAIDTTVSGFTISATDSD---GQAITISIISSPGPFKLKSDGTK- 261 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++ +++D+E SY L I+A GG + T I I ++N+ AP F + + + Sbjct: 262 ILTNGESIDFETTSSYTLTIQALAGGETDNATVT---ITIGNINE-APSFALASYSGRIH 317 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN G I+ V A D D G +TY+++ + L +G + SG LD E Sbjct: 318 ENSVNGTDIITVTASDVDSGDT--ITYSLSGSGSSSFSALT------TGVIEVSGSLDFE 369 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 Y L +TATD G +AT T F Y +AE++ + VVT Sbjct: 370 ATPTYTLTLTATDTGGLTDTATLTISVDNVNESPV---FTSASYAASVAENDAAAS-VVT 425 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 + ATD D N + Y +TG G T G++ + Q LD++ + Y LTV+A+D Sbjct: 426 VAATDPDVGNSVTYSLTGS---GSSHFTVHPTSGVVILTQALDYETKPTYSLTVAASDGQ 482 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 G T + I +TDAN+ AP+ +A Y+AS+ EDAP+GT V+ SATD D G I+YS Sbjct: 483 GGLATTSLTITVTDAND-APISVSASYSASIEEDAPVGTNVIQTSATDVDSG--DTISYS 539 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 LS AH F I TG I T + LD ET S Y LTV+ DG +LS T V Sbjct: 540 LSGS------AH----FSIT-GTGLIKTAESLDYETTSSYSLTVSFFDG---TLSVTKAV 585 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ISV + ND PV YTA++ E +LVGT+V V ATDAD + Y L Sbjct: 586 SISVTNKND-APVLPSSPYTASVSEGSLVGTAVYDVNATDAD---GDTLTYSL--YGAGS 639 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 SF I A+GV+ T KALD E+V ++ L DG +++ V I + NDSP F Sbjct: 640 SSFSISSATGVVTTAKALDYEAVTSYTLTIRVTDGNGGITETSLTV--TITNSNDSPQ-F 696 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 S + EN GT++ + A D D G N + YS+ G ++++ FS+ + G Sbjct: 697 LSTPYNTAVDENLGTGTSVISVSAIDQDSG-NTLT-YSLSGTNNAH-FSISSASGL---- 749 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 + T LD+E+ Y L + + + + I VT+ ND AP + + ++ Sbjct: 750 VTTAQALDHEAV-SSYSLTVSVSDGTVTVTTALVITVTNRND-APAFSNAPYSASVAENN 807 Query: 808 FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 + V A D D D + Y +SG + ++ +TG +TL+ LN ++ + Sbjct: 808 AGSAVY-TVSATDEDSGDTMTY-FISGTGSGDFSIDSSTGVVTLARALNYEDTTYYSLSI 865 Query: 868 SVTDGVNE 875 V DG E Sbjct: 866 LVLDGKGE 873 Score = 256 bits (627), Expect = 2e-67 Identities = 261/873 (29%), Positives = 400/873 (45%), Gaps = 95/873 (10%) Query: 14 LDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPE 73 +D + SPVF Y ASV E + +V+T+ ATD D+G + V Y++ Sbjct: 396 VDNVNESPVFTSASYAASVAEN-DAAASVVTVAATDPDVGNS--VTYSL----------- 441 Query: 74 DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133 F + SG ++ +LD E Y++ V A+D + +T Sbjct: 442 ---------TGSGSSHFTVHPTSGVVILTQALDYETKPTYSLTVAASDGQGGL-----AT 487 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 ++ + + D ND P +Y+ S++ED V N + + ATD D G I Y++ G Sbjct: 488 TSLTITVTDAND-APISVSASYSASIEEDAPVGTN--VIQTSATDVDSG--DTISYSLSG 542 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 FSI +G + ++LDYE SY L + DG + S T + I++ + ND Sbjct: 543 ---SAHFSITG-TGLIKTAESLDYETTSSYSLTVSFFDG---TLSVTKAVSISVTNKND- 594 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 AP +S + SVSE +G ++ V A DAD LTY++ G +I Sbjct: 595 APVLPSSPYTASVSEGSLVGTAVYDVNATDAD---GDTLTYSL-----YGAGSSSFSISS 646 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 +G V T+ LD E Y L + TDG T T F+ Y Sbjct: 647 ATGVVTTAKALDYEAVTSYTLTIRVTDGNG---GITETSLTVTITNSNDSPQFLSTPYNT 703 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 + E+ GT V++++A D D N L Y ++G N FSI+S + GL+T AQ LD + Sbjct: 704 AVDENLGTGTSVISVSAIDQDSGNTLTYSLSGTN-NAHFSISSAS--GLVTTAQALDHEA 760 Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y LTVS +D TA+V I +T+ N+ AP F NAPY+ASV E+ G+ V VSA Sbjct: 761 VSSYSLTVSVSDGTVTVTTALV-ITVTNRND-APAFSNAPYSASVAEN-NAGSAVYTVSA 817 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 TD D G +TY +S S + F I+ TG +T + L+ E + Y L++ Sbjct: 818 TDEDSG--DTMTYFISGTGSGD--------FSIDSSTGVVTLARALNYEDTTYYSLSILV 867 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 DG SD+T++ I+V D ND PVF Y A+I E +GT+V + ATD D + Sbjct: 868 LDG--KGESDSTNLNITVTDAND-APVFLSTPYAAHISEGVAIGTNVLKATATDQDT--S 922 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 + Y L F + ++G+I T LDRESV+++ L +++ GT + T V Sbjct: 923 DTLTYAL--TGTNSAHFAVS-STGMISTAHVLDRESVSSYSL-TLSVSDGT--ANVTQGV 976 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 I + + ND PVF + ++E G + +G + +S+ G S Sbjct: 977 SITVVNAND-VPVFTGAPYSSTVAE----GDAAAAVYTASATDGDGDTLVFSL-SGTGST 1030 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW-NDVRVEILVTDVNDNAP 792 SFS+ G + L+YE+ Y L IRA + I VT+ ND +P Sbjct: 1031 SFSMNPSTG----VITLTAALNYET-SPAYSLTIRADDGNGGVATTTLNITVTNQND-SP 1084 Query: 793 VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851 V + P+G +V A D D D L Y LSG+N+ + +TG +T Sbjct: 1085 VFSGTP-FSATLTENDPIGTTVLKVIAIDEDSADTLSYS-LSGSNSAHFAIGSSTGVITT 1142 Query: 852 SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + L+ ++ VSV+DG + + +++ Sbjct: 1143 AQLLDRETVNSYSLTVSVSDGTATVNQALSVTI 1175 Score = 252 bits (616), Expect = 4e-66 Identities = 255/906 (28%), Positives = 419/906 (46%), Gaps = 100/906 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND P+F + ASV E ++ ++LTL ATD+D + +++T L Sbjct: 1693 ITVIDSND-LPLFVDAPFSASVNENTTT-VSLLTLTATDED---------SSDMLTFSLL 1741 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P ++F I SG + ++LD E + Y + V+ +D V+ Sbjct: 1742 GPGS-------------ELFSIHPTSGVVSVTSALDAEVTSLYVLTVRVSDGKGGVN--- 1785 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+++ V +ID ND P F Y SV E + + V+ I ATD D ++ Y+ Sbjct: 1786 --TSSLSVTVIDVNDR-PAFVGAPYAASVSERLP-SGTGVVTLI-ATDQD---GDSLTYS 1837 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I G N FSI +G + + LDYE V SY L DG S + TT + I++ + Sbjct: 1838 ISGTN-HGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDG---SVTVTTSVTISVTNT 1893 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND P +S + S++EN S++ + D+D LTY++T TG+ D + Sbjct: 1894 ND-PPTLSSSYYNVSINEN-DAALSVIDITGSDSD---GDTLTYSLTG---TGSGD--FS 1943 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ++ +G + + LD E+++ Y L + TD + T + G Sbjct: 1944 MNSATGLITLATALDYESRSAYSLTIRVTD----TKEGVVTASLFVTVVDQNDTPVLTGS 1999 Query: 371 -YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y + E+ G V + A+D D + ++Y ++G N+ FSI+S G+IT A+ L Sbjct: 2000 PYTARIEENLSSGGVVAHVVASDQDSADTMNYTLSGTNS-AHFSISS---AGVITSARVL 2055 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 D++ Y L V TD + T V + + DAN+ APVF N+ +TA V E+ G V Sbjct: 2056 DYESVSAYTLGVQVTDGTATASTT-VTVTVVDAND-APVFSNSTFTAQVSEN-DAGAAVC 2112 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 VSATD+D G +TY+L S+ QF ++ TG +T + +LD E S ++L Sbjct: 2113 TVSATDADSGPADTLTYTLYGASSS--------QFSLHASTGVVTLSNVLDYEEASQHVL 2164 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 TV DG ++S T + I V + ND PVF+ YT +I E+ G+SV ATD D Sbjct: 2165 TVRVSDGRGGTVS--TSLTIKVQNQND-PPVFRGTPYTTSIDENLSAGSSVFVAIATDED 2221 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G Y + + + F + A+G++ T K LD E + ++ L D S Sbjct: 2222 NG--DTCTYSISGVNSSD--FTMASATGILTTLKVLDFEQLNSYSLTVTVTDS---TSSV 2274 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + + I + D+NDSP ++ + + ENS I ++ + A D D N + YS+ G Sbjct: 2275 SQPITITVSDVNDSPGFLDAP-YSISVQENS-INASLCTVSASDED---NDTLSYSLT-G 2328 Query: 730 DDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 ++ F++ + G LVT+ L+YE VI + N + + V DVN Sbjct: 2329 SGASYFTIHSATG-----LVTLAKSLNYEGSSMFSLTVIVSDVQGASNTSTLTVNVLDVN 2383 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKLQYRILSGNNANLILLNETTG 847 D + + + ++ G + A D D D L Y + N+A+ + N TG Sbjct: 2384 DEPQFINSPYSV--SIRENLATGTRVLQASAADEDTGDTLTYSLSGSNHAHFSISN--TG 2439 Query: 848 SMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN----SITVRLNDM 903 ++ + ++ V ++ V+V+DG + + +SV + + + + T+ N Sbjct: 2440 VISTASGIDFEVVSSYSLSVAVSDGTVSVSEPVMISVENLNDSPVFTDAPYNATINENTS 2499 Query: 904 TAEQFL 909 TA L Sbjct: 2500 TATSIL 2505 Score = 235 bits (574), Expect = 5e-61 Identities = 240/797 (30%), Positives = 364/797 (45%), Gaps = 68/797 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I +G + A+LD E + Y + V+ D +++ T++V + D ND+ P Sbjct: 1552 FVIHASTGVVSLSAALDYEVKSSYVLGVEVRDGQGG-----TASTTLNVTVSDANDS-PV 1605 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F Y+ V ED++V + + A D D A+ + Y + G N+ F++ + +G + Sbjct: 1606 FVGTPYSAMVAEDVNV--GHTVFRSSAVDED--ASDTLTYTLSGTNST-HFTMATSTGII 1660 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + + LDYE + SY L I DG + S T + I + D ND P F + F SV+EN Sbjct: 1661 TTAEGLDYESLTSYTLTITVSDG---TASVTQPITITVIDSND-LPLFVDAPFSASVNEN 1716 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 S++ + A D D + LT+++ G +I P SG V + LD E Sbjct: 1717 TTT-VSLLTLTATDEDS--SDMLTFSL-----LGPGSELFSIHPTSGVVSVTSALDAEVT 1768 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 + Y L V +DG + F+ Y ++E P GT VVTL Sbjct: 1769 SLYVLTVRVSDG---KGGVNTSSLSVTVIDVNDRPAFVGAPYAASVSERLPSGTGVVTLI 1825 Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 ATD D D+ L Y I+G N G FSI+ GLI AQ LD++ Y LT S TD G Sbjct: 1826 ATDQDGDS-LTYSISGTN-HGHFSISPST--GLIQTAQILDYESVNSYTLTASVTD-GSV 1880 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 + T V I++T+ N+ P ++ Y S+ E+ +V+ ++ +DSD +TYSL+ Sbjct: 1881 TVTTSVTISVTNTND-PPTLSSSYYNVSINEN-DAALSVIDITGSDSD---GDTLTYSLT 1935 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 S + F +N TG IT LD E+ S Y LT+ D + T + + Sbjct: 1936 GTGSGD--------FSMNSATGLITLATALDYESRSAYSLTIRVTDTKEGVV--TASLFV 1985 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 +VVD ND PV YTA I E+ G V+ V A+D D ++Y L Sbjct: 1986 TVVDQNDT-PVLTGSPYTARIEENLSSGGVVAHVVASDQDSA--DTMNYTL--SGTNSAH 2040 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F I A GVI + + LD ESV+ + L V + GT S+TV V + D ND+ PVF + Sbjct: 2041 FSISSA-GVITSARVLDYESVSAYTL-GVQVTDGTATASTTVTV--TVVDANDA-PVFSN 2095 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 T +SEN G + + A D D GP + Y++ G S+ FSL G +V Sbjct: 2096 STFTAQVSEND-AGAAVCTVSATDADSGPADTLTYTLYGA-SSSQFSLHASTG-----VV 2148 Query: 750 TMVD-LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 T+ + LDYE ++ L +R S V + + N N P + + + Sbjct: 2149 TLSNVLDYEE-ASQHVLTVR-VSDGRGGTVSTSLTIKVQNQNDPPVFRGTPYTTSIDENL 2206 Query: 809 PVGPFGRVP-AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 G V A D D D Y I SG N++ + TG +T L+ ++ V Sbjct: 2207 SAGSSVFVAIATDEDNGDTCTYSI-SGVNSSDFTMASATGILTTLKVLDFEQLNSYSLTV 2265 Query: 868 SVTDGVNEIKAMMQLSV 884 +VTD + + + ++V Sbjct: 2266 TVTDSTSSVSQPITITV 2282 Score = 230 bits (563), Expect = 1e-59 Identities = 209/675 (30%), Positives = 320/675 (47%), Gaps = 81/675 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + + ND SP F Y +V E +GT+V+++ A DQD G T+ + T Sbjct: 685 VTITNSND-SPQFLSTPYNTAVDENLGTGTSVISVSAIDQDSGN------TLTYSLSGTN 737 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N F I SG + T +LD E V+ Y++ V +D V+ L Sbjct: 738 NAH----------------FSISSASGLVTTAQALDHEAVSSYSLTVSVSDGTVTVTTAL 781 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T T + ++ P FS Y+ SV E+ + + + ATD D G + Y Sbjct: 782 VITVT-------NRNDAPAFSNAPYSASVAENNA---GSAVYTVSATDEDSG--DTMTY- 828 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I G FSIDS +G V+L + L+YE Y L I DG S++T L I + D Sbjct: 829 FISGTGSGDFSIDSSTGVVTLARALNYEDTTYYSLSILVLDG--KGESDSTNLNITVTDA 886 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND AP F ++ + +SE V IG ++++ A D D + LTY +T T + ++ Sbjct: 887 ND-APVFLSTPYAAHISEGVAIGTNVLKATATDQD--TSDTLTYALTG---TNSAHFAVS 940 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +G + T+ LDRE+ + Y L ++ +DG +A T G Sbjct: 941 ---STGMISTAHVLDRESVSSYSLTLSVSDG-----TANVTQGVSITVVNANDVPVFTGA 992 Query: 371 -YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y +AE + V T +ATD D D L + ++G G S + G+IT+ L Sbjct: 993 PYSSTVAEGDAAAA-VYTASATDGDGDT-LVFSLSG---TGSTSFSMNPSTGVITLTAAL 1047 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 +++ Y LT+ A D G T + I +T+ N+ +PVF P++A++ E+ PIGTTVL Sbjct: 1048 NYETSPAYSLTIRADDGNGGVATTTLNITVTNQND-SPVFSGTPFSATLTENDPIGTTVL 1106 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V A D D ++YSLS SN A F I TG ITT +LLDRET++ Y L Sbjct: 1107 KVIAIDEDSADT--LSYSLSG--SNSA------HFAIGSSTGVITTAQLLDRETVNSYSL 1156 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 TV+ DG + + + +++ D ND P+F Y A + E+A G SV V ATDAD Sbjct: 1157 TVSVSDG---TATVNQALSVTINDAND-APLFTNAPYNATVNENAGSG-SVYTVSATDAD 1211 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 + I Y + ++ F I +SG++ A+D E+ ++ L A D T + Sbjct: 1212 SDV---IAYSIYGHGSDK--FSIHSSSGLVTLASAVDFETKSSFVLTVQAAD--TNGAIA 1264 Query: 670 TVIVHIKIEDINDSP 684 T +++ + + NDSP Sbjct: 1265 TTSLYVDVVNQNDSP 1279 Score = 229 bits (561), Expect = 2e-59 Identities = 175/572 (30%), Positives = 267/572 (46%), Gaps = 40/572 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ PVF Y S+ E S+GT V+ + ATD D G NAE+ Y+I V D Sbjct: 5080 RIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSI--VGGDA 5137 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N F ++ +G + T A+LDRE +A YT+LV+A+D+ P Sbjct: 5138 KNQ-----------------FSVNS-TGMIRTIATLDREDIASYTLLVQASDRGVPPQ-- 5177 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T + V I+D NDN FS+ ++ V ED V I A+DAD G N+ + Y Sbjct: 5178 -TETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFR--FMNISASDADSGDNARLTY 5234 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I GNT +I+S +G + V D E+ +Y L IRA D G+P +T I I D Sbjct: 5235 SIQSGNTDNVVAIESATGALYSVGAFDRERTATYTLAIRAIDAGNPPLFSTITAHIVIID 5294 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F + + V+EN P G SI V+A D D G +A+L YT+ + + Sbjct: 5295 RNDNTPTFLDADYNFVVTENQPGGLSIGHVRAIDIDNGTHAQLVYTIEPSPNSNH----F 5350 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFM 367 T++P +G ++T+ LDRE Y+L V TD P T T F Sbjct: 5351 TMNPITGGLFTAMALDRENVPYYRLTVRVTDSAAYPSQLFNTTTVHITVLDLNDNPPAFD 5410 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITV 425 + +AE+ G V +TA+D D D RL Y +T + + G + + Sbjct: 5411 KAVFNASIAENSESGASVTRVTASDRDRDANARLTYSLTYNASSPEY-FRLDEATGEVFL 5469 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 +D++ + +TV+A D G S + +++++ D N+ APVF Y + D Sbjct: 5470 KSGVDYENVQIIEVTVTAKDDGFPSLSGSTTLRVHVIDLNDNAPVFSATFYETEIRSDHN 5529 Query: 484 IGT-TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +G ++ ++A D D G N+ +TY L + + + V+ GA R Sbjct: 5530 LGPPAIITLTAIDRDSGPNSAVTYELEQTQEKFKLDTNSGEIVLKASPGAGQIYSFRARA 5589 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 SG + V DT D E ++VD+ Sbjct: 5590 KDSG---SPQLSSSYVNVRVDTIDAEQTMVDI 5618 Score = 208 bits (508), Expect = 5e-53 Identities = 193/643 (30%), Positives = 309/643 (48%), Gaps = 62/643 (9%) Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDADEGVNAELTYTMTDKDYTGNV 305 +DV P F ++ + +V+ENV I ++ + A D+D +T ++ Sbjct: 199 QDVQGAPPVFGSAAYSGTVNENVAIDTTVSGFTISATDSD---GQAITISIISSPG---- 251 Query: 306 DLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 P + + T+G+ +D ET + Y L + A GG+ +AT T Sbjct: 252 --PFKLKSDGTKILTNGESIDFETTSSYTLTIQALAGGETD-NATVT---ITIGNINEAP 305 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 F Y + E+ GT ++T+TA+D D + + Y ++G + ++T+ G+I Sbjct: 306 SFALASYSGRIHENSVNGTDIITVTASDVDSGDTITYSLSGSGSSSFSALTT----GVIE 361 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 V+ LDF+ Y LT++ATD+GG +DTA + I++ + N +PVF +A Y ASV E+ Sbjct: 362 VSGSLDFEATPTYTLTLTATDTGGLTDTATLTISVDNVNE-SPVFTSASYAASVAEN-DA 419 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 +V+ V+ATD DVG +TYSL+ S+ F ++P +G + + LD ET Sbjct: 420 AASVVTVAATDPDVG--NSVTYSLTGSGSS--------HFTVHPTSGVVILTQALDYETK 469 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y LTV A D G L+ TT + I+V D ND P+ Y+A+I EDA VGT+V Q Sbjct: 470 PTYSLTVAASD-GQGGLA-TTSLTITVTDAND-APISVSASYSASIEEDAPVGTNVIQTS 526 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D G I Y L F I +G+I+T ++LD E+ +++ L DG Sbjct: 527 ATDVDSG--DTISYSLS----GSAHFSI-TGTGLIKTAESLDYETTSSYSLTVSFFDG-- 577 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 S T V I + + ND+ PV S T +SE S +GT + ++ A D D + Y Sbjct: 578 -TLSVTKAVSISVTNKNDA-PVLPSSPYTASVSEGSLVGTAVYDVNATDAD---GDTLTY 632 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW-NDVRVEIL 783 S+ G S+SFS+ + G + T LDYE+ Y L IR + + + Sbjct: 633 SLYGA-GSSSFSISSATG----VVTTAKALDYEAV-TSYTLTIRVTDGNGGITETSLTVT 686 Query: 784 VTDVNDNAPVMKDFQIIFNNYKD-CFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLIL 841 +T+ ND+ + +N D G V A D D + L Y + NNA+ Sbjct: 687 ITNSNDSPQFL---STPYNTAVDENLGTGTSVISVSAIDQDSGNTLTYSLSGTNNAH-FS 742 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 ++ +G +T + L+ ++ VSV+DG + + ++V Sbjct: 743 ISSASGLVTTAQALDHEAVSSYSLTVSVSDGTVTVTTALVITV 785 Score = 198 bits (483), Expect = 5e-50 Identities = 176/642 (27%), Positives = 271/642 (42%), Gaps = 63/642 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + N++ P F Y + +E + G T+ T+ ATD D G + + + I Sbjct: 3848 VQITGANEYEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAI-------- 3899 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D F ID SG + + LDRE Y + V A D SP Sbjct: 3900 -----------IAGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSP---NK 3945 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS A++ V ++D NDN P S + V V E+ SV + +++ D D GANS + Y Sbjct: 3946 SSNASVDVTVVDVNDNAPNCSVTAHVVEVAENASV--GSTVLELRCEDVDEGANSQLTYN 4003 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-----GSPSRSNTTQLLI 245 I T D D V D E + + + G +R +T + Sbjct: 4004 I---TTDKDDDGDGDDNDGDAVDC-DSEGNTNSDFTLNSSSGVLTVASQLNRESTVYYDL 4059 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + + P T Q S+SE+V +G ++ A D D+G + +TY + +GN Sbjct: 4060 TVTITDSGTPPLTTLHLQHSLSEDVSLGTTVFIAHAQDYDDGEHGHVTYAIL----SGNT 4115 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXX 363 +D SG + LD E + Y+L++ A+DG + +S+ T Sbjct: 4116 ADTFLLDKYSGSLQLLRSLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNK 4175 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRL-HYEITGGNTRGRFSITSQNGRG 421 V L E GT + + +D+D DN L Y+I GN G+F++TS G Sbjct: 4176 PECSETTKHVSLLESVVVGTVIFSTNCSDSDSSDNALLTYQILTGNAEGKFNVTSG---G 4232 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAP--YTAS 477 +T+A L + Y L V+ D+G S V + + N + P F Y+ + Sbjct: 4233 EVTLASGLSVEMTSWYHLVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDLYSLN 4292 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTN 536 VFE+ +GT V D+D G++ + +SL V+ +DQ F + P +G + Sbjct: 4293 VFENVTLGTIVFQAQVQDNDTGLHGTLRFSL--------VSGNDQGCFYLEPSSGMLVLV 4344 Query: 537 KLLDRETMSGYLLTVTARDGGV--PSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 LDRET+ Y + V D P + S V I+V+DVNDN+P LY+A+I E Sbjct: 4345 SPLDRETVDHYSVMVKVEDSSQSDPDVRSSNVTVAITVLDVNDNDPECVPALYSADISEG 4404 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 G V + + D G G L D EG PA Sbjct: 4405 K--GEFVPALYSADISEG-KGEFVPALYSADISEGKGEFVPA 4443 Score = 190 bits (463), Expect = 1e-47 Identities = 141/464 (30%), Positives = 216/464 (46%), Gaps = 41/464 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +H + +LD ND++ VF + A V E A G + + A+D D G NA + Y+I+ Sbjct: 5181 VHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGN 5240 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D +V I+ +GAL + + DRE+ A YT+ ++A D +P Sbjct: 5241 TD-------------------NVVAIESATGALYSVGAFDRERTATYTLAIRAIDAGNP- 5280 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L ST T H+ IID NDN P F + Y V E + I ++A D D G ++ Sbjct: 5281 --PLFSTITAHIVIIDRNDNTPTFLDADYNFVVTE--NQPGGLSIGHVRAIDIDNGTHAQ 5336 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSR-SNTTQLL 244 + Y I F+++ ++G + LD E V YRL +R D + PS+ NTT + Sbjct: 5337 LVYTIEPSPNSNHFTMNPITGGLFTAMALDRENVPYYRLTVRVTDSAAYPSQLFNTTTVH 5396 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I + D+NDN P F ++F S++EN G S+ RV A D D NA LTY++T Y + Sbjct: 5397 ITVLDLNDNPPAFDKAVFNASIAENSESGASVTRVTASDRDRDANARLTYSLT---YNAS 5453 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +D +G V+ +D E ++ VTA D G P S + T Sbjct: 5454 SPEYFRLDEATGEVFLKSGVDYENVQIIEVTVTAKDDGFPSLSGSTTLRVHVIDLNDNAP 5513 Query: 365 XFMPGQYEVELAEDEPPGTP-VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 F YE E+ D G P ++TLTA D D ++ + YE+ T+ +F + + +G Sbjct: 5514 VFSATFYETEIRSDHNLGPPAIITLTAIDRDSGPNSAVTYELE--QTQEKFKLDTNSGE- 5570 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDA 462 ++ A P + Y A DSG S V+++ DA Sbjct: 5571 IVLKASP---GAGQIYSFRARAKDSGSPQLSSSYVNVRVDTIDA 5611 Score = 185 bits (450), Expect = 5e-46 Identities = 254/939 (27%), Positives = 384/939 (40%), Gaps = 116/939 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD------------------I 52 I V + ND SPVF + A++ E GTTVL + A D+D I Sbjct: 1075 ITVTNQND-SPVFSGTPFSATLTENDPIGTTVLKVIAIDEDSADTLSYSLSGSNSAHFAI 1133 Query: 53 GKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI---DGRSGALLTRASLD--- 106 G + V T +L+ +T+N V + D L T A + Sbjct: 1134 GSSTGVITTAQLLDRETVNSYSLTVSVSDGTATVNQALSVTINDANDAPLFTNAPYNATV 1193 Query: 107 REKVARYTVL-VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165 E +V V ATD S V +I+ + D + T +VD + Sbjct: 1194 NENAGSGSVYTVSATDADSDVI-----AYSIYGHGSDKFSIHSSSGLVTLASAVDFE--- 1245 Query: 166 TDNPVIAKIKATDADVG-ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 T + + ++A D + A +++ ++ N F S + + LDYE SY Sbjct: 1246 TKSSFVLTVQAADTNGAIATTSLYVDVVNQNDSPAFMGTPYSTSI-IESALDYESASSYS 1304 Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 L + DG + S TT L I+I DVND AP F ++ + SV+EN G ++ V D Sbjct: 1305 LTVTVNDG---TVSMTTPLTISIADVND-APVFTSAPYTTSVNEN-EAGAAVYTVSGTDQ 1359 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 D G + T + Y T+ P +G V S LD ET Y L + A+D Sbjct: 1360 DSGDSVSFTMYGSGSSY-------FTLHPTTGVVTLSRALDYETTPLYTLTIIASDTNQG 1412 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404 S T T + Y ++ E+ G V+ LTATD D ++ L Y +T Sbjct: 1413 LASTTLTVTVTDQNDEPK---LVGTPYYAQVDENLNSGATVMKLTATDQDSNSTLSYTLT 1469 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464 G N G FSI++ GLIT Q LD++ Y L VS TD G + T + I + + N+ Sbjct: 1470 GSNN-GHFSISAT---GLITTTQELDYETINTYSLNVSVTD-GTTTVTEGLTITVRNKND 1524 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 F AP TV +A VG F Sbjct: 1525 DPS-----------FTSAPYSATVTENNAVPPWVG---------------------SADF 1552 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 VI+ TG ++ + LD E S Y+L V RDG + S T +V +S D ND+ PVF Sbjct: 1553 VIHASTGVVSLSAALDYEVKSSYVLGVEVRDGQGGTASTTLNVTVS--DANDS-PVFVGT 1609 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 Y+A + ED VG +V + A D D + + Y L + F + ++G+I T + Sbjct: 1610 PYSAMVAEDVNVGHTVFRSSAVDEDA--SDTLTYTLSGTNSTH--FTMATSTGIITTAEG 1665 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LD ES+ ++ L DG S T + I + D ND P+F + ++EN+ T Sbjct: 1666 LDYESLTSYTLTITVSDG---TASVTQPITITVIDSNDL-PLFVDAPFSASVNENT---T 1718 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 T+ + DE + ++ +S+ G S FS+ G + + +D + S Y Sbjct: 1719 TVSLLTLTATDEDSSDMLTFSLL-GPGSELFSIHPTSG--VVSVTSALDAEVTS---LYV 1772 Query: 765 LVIRAASPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 L +R + N + + V DVND P + + P G G V D Sbjct: 1773 LTVRVSDGKGGVNTSSLSVTVIDVNDR-PAFVGAPYA-ASVSERLPSGT-GVVTLIATDQ 1829 Query: 824 T-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL 882 D L Y I SG N ++ +TG + + L+ T+ SVTDG + + + Sbjct: 1830 DGDSLTYSI-SGTNHGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDGSVTVTTSVTI 1888 Query: 883 SVRLITEEMLLNS--ITVRLNDMTAEQFLSPLLGFFIDG 919 SV + L+S V +N+ A + + G DG Sbjct: 1889 SVTNTNDPPTLSSSYYNVSINENDAALSVIDITGSDSDG 1927 Score = 112 bits (269), Expect = 4e-24 Identities = 127/435 (29%), Positives = 199/435 (45%), Gaps = 42/435 (9%) Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTV--LVVSATDSDVGINAQITYSLSSE 511 +V D PVF +A Y+ +V E+ I TTV +SATDSD IT S+ S Sbjct: 193 LVSFVCQDVQGAPPVFGSAAYSGTVNENVAIDTTVSGFTISATDSD---GQAITISIISS 249 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 + + T +T + +D ET S Y LT+ A GG +D V I++ Sbjct: 250 PGPFKLK--------SDGTKILTNGESIDFETTSSYTLTIQALAGGE---TDNATVTITI 298 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 ++N+ P F Y+ I E+++ GT + V A+D D G I Y L S + Sbjct: 299 GNINE-APSFALASYSGRIHENSVNGTDIITVTASDVDSG--DTITYSLSGSGSSSFSAL 355 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 +GVI + +LD E+ T+ L A D G ++T+ I ++++N+S PVF S Sbjct: 356 ---TTGVIEVSGSLDFEATPTYTLTLTATDTGGLTDTATLT--ISVDNVNES-PVFTSAS 409 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 ++EN + + + A DPD G N+V YS+ G S+ F++ G ++T Sbjct: 410 YAASVAENDAAASVV-TVAATDPDVG-NSVT-YSLTGSGSSH-FTVHPTSG---VVILTQ 462 Query: 752 VDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 LDYE+ + Y L + A+ + I VTD ND AP+ + +D PV Sbjct: 463 A-LDYET-KPTYSLTVAASDGQGGLATTSLTITVTDAND-APISVSASYSASIEEDA-PV 518 Query: 811 GP-FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 G + A D D D + Y LSG +A+ + TG + + L+ ++ VS Sbjct: 519 GTNVIQTSATDVDSGDTISYS-LSG-SAHFSITG--TGLIKTAESLDYETTSSYSLTVSF 574 Query: 870 TDGVNEIKAMMQLSV 884 DG + + +SV Sbjct: 575 FDGTLSVTKAVSISV 589 Score = 44.0 bits (99), Expect = 0.002 Identities = 52/226 (23%), Positives = 96/226 (42%), Gaps = 13/226 (5%) Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 +V +D+ +PPVF S + ++EN I TT+ D A+ +I Sbjct: 193 LVSFVCQDVQGAPPVFGSAAYSGTVNENVAIDTTVSGFTISATDSDGQAI---TISIISS 249 Query: 732 SNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790 F L+ SD +++T + +D+E+ Y L I+A + ++ V I + ++N+ Sbjct: 250 PGPFKLK----SDGTKILTNGESIDFET-TSSYTLTIQALAGGETDNATVTITIGNINE- 303 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850 AP +++ V A D D D + Y + +++ L TTG + Sbjct: 304 APSFALASYSGRIHENSVNGTDIITVTASDVDSGDTITYSLSGSGSSSFSAL--TTGVIE 361 Query: 851 LSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNS 895 +S L+ T+ ++ TD G A + +SV + E + S Sbjct: 362 VSGSLDFEATPTYTLTLTATDTGGLTDTATLTISVDNVNESPVFTS 407 >SB_48962| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2225 Score = 345 bits (848), Expect = 3e-94 Identities = 246/789 (31%), Positives = 384/789 (48%), Gaps = 53/789 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+LD ND+SP ++Y A V E + GT V T+KATD D G N EVEY I T Sbjct: 152 INILDVNDNSPQPARREYRAHVAENSDVGTLVTTVKATDPDAGVNGEVEYCI----VQTA 207 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 E A +F+I+ SG +LT LD E + + + +KA+D+ P + L Sbjct: 208 KAESAS------------LFKIESHSGRILTVKPLDYETMQEHVLTIKASDRGIPKRETL 255 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S V++ D ND+ P+F + VD +S I ++ ATD D G NS ++Y+ Sbjct: 256 FSVV---VSVDDVNDHKPEFLSPLFESEVD--VSAKAGTAILRVIATDKDDGTNSKLKYS 310 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ GNT S+D SG V + L V Y L +++ DGG P + N ++ Sbjct: 311 IVSGNTNKSLSVDQNSGVVKVAGRLS-TLVHQYALKVQSTDGGEPPLKTQVDVKYNQKEC 369 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND AP F SL+ ++SE+ P+ ++V V+A D D G+N E+ Y + + G Sbjct: 370 NDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSRVGAF---FK 426 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID +SG V+ + LD E++ +++++ A D G P + F Sbjct: 427 IDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGETRVRVVLMDANDNAPRFDKSM 486 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y + PG V + ATD DE + +L Y ITGG R F I SQ+ G+IT+++ Sbjct: 487 YAASILGSASPGQFVTRILATDPDEGDAKKLRYSITGGQGRQHFQIDSQS--GVITLSRV 544 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 + KQ + Y L V +DS S T+ V++ I D N+++P+F Y S E+ P GT V Sbjct: 545 VGIKQGKVYGLDVEVSDSVHVS-TSKVRVIIGDTNDHSPIFSEDVYKVSFNENYPEGTFV 603 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 +VSATD D G A +TYS+ S +A+ ++F I+ +G + + + DRE S + Sbjct: 604 TMVSATDLDSGNYAHLTYSIDSV---DAM----RKFRIDADSGMLYSRLMFDRENSSQAI 656 Query: 549 LTVTAR--DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 ++V R DGG VE+ ++D NDN+P+F+ + Y I +GT V A+ Sbjct: 657 MSVPIRATDGG--GRFGFCVVEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSAS 714 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D N + Y + + F I+ A+GVI+ ++ V +++ + DGG P Sbjct: 715 DPDASSNAALTYVI-VGHQTPPVFTINAATGVIQVSR---EPEVKSYNFFVLVKDGGNPL 770 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 S V I + + + F + EN+ +G + + P P V + I Sbjct: 771 LRSIASVKITVLERDARILHFGKSKYDVTVGENAEMGQIVTGLNLVVPGGNPVDVDYRII 830 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVR--VEIL 783 KG +D+N + + G D V ++ LDYE R +Y +++ A + R V + Sbjct: 831 KGNNDNN----DRKFGVDSTGRVRVIGRLDYEI-RNRYVMIVEANVSAINQIARTVVVVQ 885 Query: 784 VTDVNDNAP 792 V D+ND P Sbjct: 886 VLDINDVTP 894 Score = 291 bits (713), Expect = 7e-78 Identities = 242/818 (29%), Positives = 379/818 (46%), Gaps = 56/818 (6%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 N +CND +P F Y A++ E T V+T+KA D D G N E+ Y I+ V+ Sbjct: 365 NQKECNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSR---- 420 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 V F+ID +SG + SLD E + +++ A D+ P L+ Sbjct: 421 --------------VGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKP---SLT 463 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 + V ++D NDN P+F + Y S+ S + + +I ATD D G +RY+I Sbjct: 464 GETRVRVVLMDANDNAPRFDKSMYAASILG--SASPGQFVTRILATDPDEGDAKKLRYSI 521 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 GG + F IDS SG ++L + + +Q + Y L + D S T+++ + I D N Sbjct: 522 TGGQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDSVHVS---TSKVRVIIGDTN 578 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 D++P F +++ S +EN P G + V A D D G A LTY++ D I Sbjct: 579 DHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRK----FRI 634 Query: 312 DPRSGWVYTSGQLDRE--TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 D SG +Y+ DRE +QA + + ATDGG R F Sbjct: 635 DADSGMLYSRLMFDRENSSQAIMSVPIRATDGGG--RFGFCVVEVHLIDENDNQPIFELK 692 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y+ ++ GTPV+ +A+D D + L Y I G T F+I + G+I V++ Sbjct: 693 NYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVIVGHQTPPVFTINA--ATGVIQVSR 750 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + K +VL + RS A V+I + + + F + Y +V E+A +G Sbjct: 751 EPEVKSYNFFVLVKDGGNPLLRS-IASVKITVLERDARILHFGKSKYDVTVGENAEMGQI 809 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V ++ G + Y + +N+ ++D++F ++ TG + LD E + Y Sbjct: 810 VTGLNLVVPG-GNPVDVDYRIIKG-NND---NNDRKFGVD-STGRVRVIGRLDYEIRNRY 863 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 ++ V A + ++ T V + V+D+ND P F Y A+I E+ +G+ V +V A D Sbjct: 864 VMIVEANVSAINQIARTV-VVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAED 922 Query: 608 ADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D G NG + Y L KD+ + F ID +G I T ALDRE + + + A D GT Sbjct: 923 LDSGSNGMVTYALVSKDKLVKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTR 982 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +S V + D+ND+PP F T + E++ IG ++ I A DE N ++Y I Sbjct: 983 LTSLTTVRAIVLDVNDTPPKFSQSEFTASVKEDALIGQSVTTITA--TDEDLNTELYYFI 1040 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786 GD F +E + G + LD ES Y+L I A+ + +++I + D Sbjct: 1041 LSGDPQARFGIERKTG----VIFVHGSLDRESV-GSYDLNISASDGLFTSFAQMKIDIED 1095 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823 NDN P+ I + K+ P+G V A DADV Sbjct: 1096 ANDNPPICTQ-SIYVEHIKENTPLGSTVLTVGATDADV 1132 Score = 289 bits (710), Expect = 2e-77 Identities = 225/727 (30%), Positives = 346/727 (47%), Gaps = 59/727 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ ++D ND++P F+ Y AS+ AS G V + ATD D G ++ Y+I Sbjct: 469 RVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSI------- 521 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F+ID +SG + + ++ Y + V+ +D Sbjct: 522 ------------TGGQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDSVHV---- 565 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST+ + V I D ND+ P FSE Y VS +E+ + + + ATD D G + + Y Sbjct: 566 --STSKVRVIIGDTNDHSPIFSEDVYKVSFNENYP--EGTFVTMVSATDLDSGNYAHLTY 621 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV----IRAQDGGSPSRSNTTQLLI 245 +I + +F ID+ SG L L +++ S + + IRA DGG R + + Sbjct: 622 SIDSVDAMRKFRIDADSG--MLYSRLMFDRENSSQAIMSVPIRATDGGG--RFGFCVVEV 677 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++ D NDN P F + ++S +V +G ++ A D D NA LTY + G+ Sbjct: 678 HLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVIV-----GHQ 732 Query: 306 DLPI-TIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 P+ TI+ +G + Q+ RE + K Y V DGG+P + A+ Sbjct: 733 TPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDARI 788 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLT-ATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y+V + E+ G V L + Y I GN + G Sbjct: 789 LHFGKSKYDVTVGENAEMGQIVTGLNLVVPGGNPVDVDYRIIKGNNDNNDRKFGVDSTGR 848 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + V LD++ RYV+ V A S + +V + + D N+ P F + PY AS+ E+ Sbjct: 849 VRVIGRLDYEIRNRYVMIVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPEN 908 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 IG+ VL V A D D G N +TY+L +S + + ++F I+ TG ITT LDR Sbjct: 909 IDIGSKVLRVFAEDLDSGSNGMVTYAL---VSKDKLVK--EKFDIDQHTGWITTRGALDR 963 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E + V A D G L+ T V V+DVND P F Q +TA++ EDAL+G SV+ Sbjct: 964 EKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSEFTASVKEDALIGQSVT 1023 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + ATD D LN ++Y + D + F I+ +GVI + +LDRESV ++DL A D Sbjct: 1024 TITATDED--LNTELYYFILSGD-PQARFGIERKTGVIFVHGSLDRESVGSYDLNISASD 1080 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G +S + I IED ND+PP+ +I EN+P+G+T+ + A D D G NA Sbjct: 1081 G---LFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAE 1137 Query: 722 VHYSIKG 728 + YS+ G Sbjct: 1138 LTYSVFG 1144 Score = 285 bits (700), Expect = 3e-76 Identities = 241/850 (28%), Positives = 385/850 (45%), Gaps = 52/850 (6%) Query: 90 FRIDGRSGALLTRASL-DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND--- 145 F ID RSG + T SL D E Y + + A D P +LS++ + +++I N Sbjct: 7 FIIDSRSGEIFTNVSLVDGES---YDLTIVAEDNGLP---KLSTSTNVLIDVIQGNKPSK 60 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P F K Y+ + ED + N + I A D D I Y I GN +F+ID Sbjct: 61 NAPVFWNKQYSADIQEDKRI--NSFVLIIGAEDPDF---DQITYNIASGNHGNKFTIDRY 115 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 G +++ +LD E+ Y L + A DG + + + + INI DVNDN+P+ ++ Sbjct: 116 GGFITVAHSLDREEKSFYSLRVEATDGYNTA---SVPVTINILDVNDNSPQPARREYRAH 172 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V+EN +G + V+A D D GVN E+ Y + + L I+ SG + T LD Sbjct: 173 VAENSDVGTLVTTVKATDPDAGVNGEVEYCIVQTAKAESASL-FKIESHSGRILTVKPLD 231 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 ET ++ L + A+D G P R + F+ +E E+ GT + Sbjct: 232 YETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVSAKAGTAI 291 Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 + + ATD D+ +++L Y I GNT S+ QN G++ VA L +Y L V + Sbjct: 292 LRVIATDKDDGTNSKLKYSIVSGNTNKSLSV-DQNS-GVVKVAGRLS-TLVHQYALKVQS 348 Query: 444 TDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 TD G V + N + N+ AP F + Y A++ E P+ T V+ V A D D GIN Sbjct: 349 TDGGEPPLKTQVDVKYNQKECNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGIN 408 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 +I Y + + V+ F I+ ++G + K LD E+ + + + A D G PSL Sbjct: 409 KEINYFIQN------VSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSL 462 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 + T V + ++D NDN P F + +Y A+I+ A G V+++ ATD D G ++ Y + Sbjct: 463 TGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSIT 522 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 + F ID SGVI ++ + + + L D ST V + I D N Sbjct: 523 GGQGRQ-HFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDS---VHVSTSKVRVIIGDTN 578 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D P+F D +EN P GT + + A D D G A + YSI D F ++ Sbjct: 579 DHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADS 638 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV--MKDFQ 798 G + L M D + S + + IRA + VE+ + D NDN P+ +K++ Sbjct: 639 GMLYSRL--MFDRE-NSSQAIMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYD 695 Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLN 856 + + P A D D + L Y I+ + +N TG + +S + Sbjct: 696 TTIS--RSVTMGTPVLMTSASDPDASSNAALTYVIVGHQTPPVFTINAATGVIQVSREPE 753 Query: 857 TNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGF 915 K V V DG N ++++ + + ++ + + D+T + + +G Sbjct: 754 V---KSYNFFVLVKDGGNPLLRSIASVKITVLERDARILHFGKSKYDVTVGE--NAEMGQ 808 Query: 916 FIDGLAAIIP 925 + GL ++P Sbjct: 809 IVTGLNLVVP 818 Score = 269 bits (659), Expect = 2e-71 Identities = 239/885 (27%), Positives = 384/885 (43%), Gaps = 62/885 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V D NDH P F +E+ V A +GT +L + ATD+D G N++++Y+I V+ +T Sbjct: 260 VSVDDVNDHKPEFLSPLFESEVDVSAKAGTAILRVIATDKDDGTNSKLKYSI--VSGNT- 316 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D SG + L V +Y + V++TD P L Sbjct: 317 ----------------NKSLSVDQNSGVVKVAGRLST-LVHQYALKVQSTDGGEPP---L 356 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + N + ND P F+ Y ++ E V D V+ +KA D D G N I Y Sbjct: 357 KTQVDVKYNQKECNDVAPAFNRSLYLATISESTPV-DTAVVT-VKAIDGDSGINKEINYF 414 Query: 191 IIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I F ID SG V + K+LDYE + ++I A D G PS + T++ + + D Sbjct: 415 IQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGETRVRVVLMD 474 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDNAPRF S++ S+ + G + R+ A D DEG +L Y++T G Sbjct: 475 ANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITG----GQGRQHF 530 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ID +SG + S + + Y L V +D +T+ F Sbjct: 531 QIDSQSGVITLSRVVGIKQGKVYGLDVEVSDS---VHVSTSKVRVIIGDTNDHSPIFSED 587 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427 Y+V E+ P GT V ++ATD D N H Y I + +F I + +G + Sbjct: 588 VYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADSGMLYSRLMF 647 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + + + + ATD GGR +V++++ D N+ P+FE Y ++ +GT Sbjct: 648 DRENSSQAIMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYDTTISRSVTMGTP 707 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNKLLDRETMSG 546 VL+ SA+D D NA +TY + V H F IN TG I ++ + Sbjct: 708 VLMTSASDPDASSNAALTYVI--------VGHQTPPVFTINAATGVIQVSR---EPEVKS 756 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y V +DGG P L V+I+V++ + F + Y + E+A +G V+ + Sbjct: 757 YNFFVLVKDGGNPLLRSIASVKITVLERDARILHFGKSKYDVTVGENAEMGQIVTGLNLV 816 Query: 607 DADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 G + Y + D + F +D ++G +R LD E + + V + Sbjct: 817 -VPGGNPVDVDYRIIKGNNDNNDRKFGVD-STGRVRVIGRLDYE-IRNRYVMIVEANVSA 873 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 Q + +V +++ DIND P F SD I EN IG+ + + A D D G N +V Y Sbjct: 874 INQIARTVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTY 933 Query: 725 SIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779 ++ D F ++ G + T LD E + +E +RA + L + Sbjct: 934 ALVSKDKLVKEKFDIDQHTGW----ITTRGALDREK-QPSFEFQVRATDNGTTRLTSLTT 988 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL 839 V +V DVND P + + +D + A D D+ +L Y ILSG+ Sbjct: 989 VRAIVLDVNDTPPKFSQSEFTASVKEDALIGQSVTTITATDEDLNTELYYFILSGDPQAR 1048 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + TG + + L+ + +S +DG+ A M++ + Sbjct: 1049 FGIERKTGVIFVHGSLDRESVGSYDLNISASDGLFTSFAQMKIDI 1093 Score = 252 bits (616), Expect = 4e-66 Identities = 194/642 (30%), Positives = 308/642 (47%), Gaps = 45/642 (7%) Query: 195 NTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND- 252 N +F IDS SG++ + V +D E SY L I A+D G P S +T +LI++ N Sbjct: 2 NRDNKFIIDSRSGEIFTNVSLVDGE---SYDLTIVAEDNGLPKLSTSTNVLIDVIQGNKP 58 Query: 253 --NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NAP F+ + + E+ I ++ + A D D ++TY + +GN T Sbjct: 59 SKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFD---QITYNIA----SGNHGNKFT 111 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG- 369 ID G++ + LDRE ++ Y L V ATDG + TA+ P Sbjct: 112 IDRYGGFITVAHSLDREEKSFYSLRVEATDGYN-----TASVPVTINILDVNDNSPQPAR 166 Query: 370 -QYEVELAEDEPPGTPVVTLTATDADE--DNRLHY---EITGGNTRGRFSITSQNGRGLI 423 +Y +AE+ GT V T+ ATD D + + Y + + F I S +GR ++ Sbjct: 167 REYRAHVAENSDVGTLVTTVKATDPDAGVNGEVEYCIVQTAKAESASLFKIESHSGR-IL 225 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 TV +PLD++ + +VLT+ A+D G R V +++ D N++ P F + + + V Sbjct: 226 TV-KPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVS 284 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A GT +L V ATD D G N+++ YS+ S +N++++ DQ + G ++T Sbjct: 285 AKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSLSV-DQNSGVVKVAGRLST------ 337 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + Y L V + DGG P L DV+ + + ND P F + LY A I E V T+V Sbjct: 338 -LVHQYALKVQSTDGGEPPLKTQVDVKYNQKECNDVAPAFNRSLYLATISESTPVDTAVV 396 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A D D G+N I+Y + R F ID SGV+ K+LD ES H++ VA D Sbjct: 397 TVKAIDGDSGINKEINYFIQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAAD 456 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G P + V + + D ND+ P F+ I ++ G + I A DPDEG Sbjct: 457 EGKPSLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKK 516 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 + YSI GG F ++++ G ++T+ + K Y L + + + +V Sbjct: 517 LRYSITGGQGRQHFQIDSQSG-----VITLSRVVGIKQGKVYGLDVEVSDSVHVSTSKVR 571 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD 822 +++ D ND++P+ + + ++ + +P G F V A D D Sbjct: 572 VIIGDTNDHSPIFSE-DVYKVSFNENYPEGTFVTMVSATDLD 612 Score = 232 bits (568), Expect = 3e-60 Identities = 243/905 (26%), Positives = 390/905 (43%), Gaps = 79/905 (8%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 VQI + + N+ P F ++ Y +V EDAPIG V+ V A + N ITY++ + Sbjct: 1156 VQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVSRESS-NDVITYAILRGADS 1214 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 F I+ + G I N+ LD ET Y LTV A D G P L T+ V ISV D Sbjct: 1215 GL-------FSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRISVTDS 1267 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 NDN P F ++ Y+A + E++ +GT V QV ATD D G N +I Y + + + F I Sbjct: 1268 NDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSI-AEGNDAKKFKIVE 1326 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +GVI+ + +DRE VA++ LK A D G PPQ + +V I++ D+ND+ P F S LT Sbjct: 1327 ETGVIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTDVNDNSPEFSSTNLTT 1386 Query: 695 YISENSPIGTTIGEIRAHDPDE-GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 +SE+S + +R HD D G A +++ GD S F L + K V+ D Sbjct: 1387 VLSESSLPNAAVIHLRPHDRDALGNGAPYQFTLISGDASR-FKLHSNGLITKIGDVSHSD 1445 Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 Y + LV PP +V + + + + + P + + N Y G Sbjct: 1446 GQY----RLRVLVADNGHPPQSTEVSITVKIAESKTHPPNVHPLTVYVNLYGSNLNGGVI 1501 Query: 814 GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873 GRV A D D D L Y ++S ++L+++++ T+ + N + P + VSVTD Sbjct: 1502 GRVKATDKD-GDLLHYSLVSSEQSSLLMISD---EGTVRARANIS-PGTYNLNVSVTDKR 1556 Query: 874 NEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYI 933 + + + + V IT E +S+T+RL D++A F+ L + + ++ P NI++ Sbjct: 1557 YTVYSGVTVIVLNITPETQEHSVTLRLGDLSAGTFVEKSLEKCLLFIGKLLDVPAVNIHV 1616 Query: 934 FSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQ 993 +S+Q + N L+V + R+ G+ + P +L ++ + V+ Sbjct: 1617 WSMQP----SDNDLDVVIAVRK--RRKGM-------FKPLYLTRQLNGSHLAFEKNVGVR 1663 Query: 994 VLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGV 1053 ++ + C + C + C V K V SD V + S +C C + G Sbjct: 1664 IVTVGLSQCRAQDCPTYLVCSDVYKPELKQIRVMSDHVSYISYEHSRSHSCTCQDKNRG- 1722 Query: 1054 NCETILTKASCEVDGDGSICR---SGSQCVARREGGILCQGCSIDAAYTTAVCELRARSF 1110 C I K + G C+ G QC + C + T+ + AR+F Sbjct: 1723 -CGAI-QKCATSPCAPGYKCKDFPEGYQC--KCVDATKCHMDTTGCDDTSCIKGNNARTF 1778 Query: 1111 PVSSFLTFPGLKR---RHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRG 1167 S++ + LK + + L T + G L++ ++D+ LE+ Sbjct: 1779 NGDSYIRY-RLKETFDQPSRSIGLALKTVKSEGTLVFAA---GQYDYSILEISK------ 1828 Query: 1168 GGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAAD 1226 G LRF F G ++++ + V DG WH V +E T+ LD S Sbjct: 1829 GFIQLRFDF----GPGVVSIDWSPVNDGKWHHVAVERQGNHATVTLDYGKHQASGKSPGR 1884 Query: 1227 FGLKYACAN---FTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVG 1283 + N F KVL +R + + G + G + V KD Sbjct: 1885 MRILNLDGNSIYFGAKVLNSRI--------KRSEGQGVIVENGFKGCMQNLNVNGKDLPM 1936 Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343 S+ Y + Y + GC + C + C + + C+C GH Sbjct: 1937 TGSNTY-------ASGY--PSNAERGCRTSGACQRPQACPLASRCIETFTDRRCECLPGH 1987 Query: 1344 TGKDC 1348 +G DC Sbjct: 1988 SGPDC 1992 Score = 224 bits (548), Expect = 7e-58 Identities = 151/508 (29%), Positives = 250/508 (49%), Gaps = 41/508 (8%) Query: 5 FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 FC+ +++++D ND+ P+FE++ Y+ ++ + GT VL A+D D NA + Y I Sbjct: 672 FCV-VEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVI-- 728 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQA 123 VF I+ +G + + RE +V Y V D Sbjct: 729 -----------------VGHQTPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGG 767 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 +P+ L S A++ + +++ + F + Y V+V E+ + ++ + G Sbjct: 768 NPL---LRSIASVKITVLERDARILHFGKSKYDVTVGENAEM--GQIVTGLNLV-VPGGN 821 Query: 184 NSAIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 + Y II G N +F +DS +G V ++ LDYE Y +++ A + + ++ Sbjct: 822 PVDVDYRIIKGNNDNNDRKFGVDS-TGRVRVIGRLDYEIRNRYVMIVEA-NVSAINQIAR 879 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 T +++ + D+ND P+F + + S+ EN+ IG ++RV A D D G N +TY + KD Sbjct: 880 TVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKD 939 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 V ID +GW+ T G LDRE Q ++ V ATD G ++ T Sbjct: 940 KL--VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVN 997 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F ++ + ED G V T+TATD D + L+Y I G+ + RF I + Sbjct: 998 DTPPKFSQSEFTASVKEDALIGQSVTTITATDEDLNTELYYFILSGDPQARFGI--ERKT 1055 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G+I V LD + Y L +SA+D G + A ++I+I DAN+ P+ + Y + E Sbjct: 1056 GVIFVHGSLDRESVGSYDLNISASD-GLFTSFAQMKIDIEDANDNPPICTQSIYVEHIKE 1114 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSL 508 + P+G+TVL V ATD+DVG+NA++TYS+ Sbjct: 1115 NTPLGSTVLTVGATDADVGVNAELTYSV 1142 Score = 163 bits (396), Expect = 2e-39 Identities = 111/302 (36%), Positives = 162/302 (53%), Gaps = 28/302 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND +P F Y AS+ E G+ VL + A D D G N V Y LV+ D L Sbjct: 884 VQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYA--LVSKDKL 941 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V++ F ID +G + TR +LDREK + V+ATD + RL Sbjct: 942 ---------------VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNG---TTRL 983 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S T+ ++D ND P+FS+ +T SV ED + + + I ATD D+ N+ + Y Sbjct: 984 TSLTTVRAIVLDVNDTPPKFSQSEFTASVKEDALIGQS--VTTITATDEDL--NTELYYF 1039 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ G+ Q +F I+ +G + + +LD E V SY L I A DG ++ Q+ I+I D Sbjct: 1040 ILSGDPQARFGIERKTGVIFVHGSLDRESVGSYDLNISASDG---LFTSFAQMKIDIEDA 1096 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-TGNVDLPI 309 NDN P S++ E + EN P+G +++ V A DAD GVNAELTY++ + + T VD + Sbjct: 1097 NDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGFGTFAVDKNV 1156 Query: 310 TI 311 I Sbjct: 1157 QI 1158 Score = 157 bits (380), Expect = 2e-37 Identities = 133/486 (27%), Positives = 214/486 (44%), Gaps = 43/486 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI VL+ ND P F Y +V E A G V+ ++A ++ N + Y I L AD+ Sbjct: 1157 QIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVSRE-SSNDVITYAI-LRGADS 1214 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +F ID ++G + LD E YT+ V+A+D PV Sbjct: 1215 ------------------GLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPV--- 1253 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L ST+ + +++ D NDN P+FSEK Y+ VDE+ ++ + ++ ATD D G N+ I+Y Sbjct: 1254 LRSTSYVRISVTDSNDNGPEFSEKRYSAKVDENSAL--GTFVLQVFATDRDSGTNAQIKY 1311 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I GN +F I +G + + +D E+V SYRL +RAQD G P + T + I + D Sbjct: 1312 SIAEGNDAKKFKIVEETGVIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTD 1371 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTYTMTDKDYTGNVDLP 308 VNDN+P F ++ +SE+ +++ ++ +D D G A +T+ D L Sbjct: 1372 VNDNSPEFSSTNLTTVLSESSLPNAAVIHLRPHDRDALGNGAPYQFTLISGD-ASRFKL- 1429 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +G + G + + +Y+L V D G PP+S + P Sbjct: 1430 ----HSNGLITKIGDVS-HSDGQYRLRVLVADNGHPPQSTEVSITVKIAESKTHPPNVHP 1484 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V L G + + ATD D D LHY + I+ + G + Sbjct: 1485 LTVYVNLYGSNLNGGVIGRVKATDKDGD-LLHYSLVSSEQSSLLMISDE---GTVRARAN 1540 Query: 429 LDFKQERRYVLTVSATDSGGR--SDTAMVQINIT-DANNYAPVFENAPYTASVFEDAPIG 485 + Y L VS TD S ++ +NIT + ++ +A F + + Sbjct: 1541 I---SPGTYNLNVSVTDKRYTVYSGVTVIVLNITPETQEHSVTLRLGDLSAGTFVEKSLE 1597 Query: 486 TTVLVV 491 +L + Sbjct: 1598 KCLLFI 1603 Score = 144 bits (349), Expect = 9e-34 Identities = 109/384 (28%), Positives = 172/384 (44%), Gaps = 19/384 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + + +++ ND P+FS Y +V ED + + + +++A + +N I YAI+ G Sbjct: 1156 VQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNE--VVRVRAVSRE-SSNDVITYAILRGA 1212 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 FSID +G + + + LDYE + Y L + A D G P +T+ + I++ D NDN P Sbjct: 1213 DSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRISVTDSNDNGP 1272 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 F + V EN +G +++V A D D G NA++ Y++ + GN I + Sbjct: 1273 EFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSIAE----GNDAKKFKIVEET 1328 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 G + SG +DRE A Y+L V A D G PP+ A F L Sbjct: 1329 GVIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTDVNDNSPEFSSTNLTTVL 1388 Query: 376 AEDEPPGTPVVTLTATDADE-DNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 +E P V+ L D D N Y+ T RF + S GLIT + Sbjct: 1389 SESSLPNAAVIHLRPHDRDALGNGAPYQFTLISGDASRFKLHS---NGLITKIGDVS-HS 1444 Query: 434 ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 + +Y L V D+G +S + + I ++ + P +++ G + V Sbjct: 1445 DGQYRLRVLVADNGHPPQSTEVSITVKIAESKTHPPNVHPLTVYVNLYGSNLNGGVIGRV 1504 Query: 492 SATDSDVGINAQITYSL-SSEISN 514 ATD D + + YSL SSE S+ Sbjct: 1505 KATDKDGDL---LHYSLVSSEQSS 1525 Score = 130 bits (314), Expect = 2e-29 Identities = 97/316 (30%), Positives = 144/316 (45%), Gaps = 14/316 (4%) Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD---QQFVINPQTGA-ITTNKLL 539 +G+ L +SA+D AQ+ + N + + N G+ + T Sbjct: 1069 VGSYDLNISASDGLFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGAT 1128 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D + LT + G + + +V+I V+++ND P F +Y N+ EDA +G Sbjct: 1129 DADVGVNAELTYSVFGQGFGTFAVDKNVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNE 1188 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V +V A + N I Y + + + G F ID +G I N+ LD E+ + L A Sbjct: 1189 VVRVRAVSRE-SSNDVITYAI-LRGADSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEA 1246 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G P ST V I + D ND+ P F + + ENS +GT + ++ A D D G N Sbjct: 1247 SDAGPPVLRSTSYVRISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTN 1306 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776 A + YSI G+D+ F + G K D+D E Y L +RA PP Sbjct: 1307 AQIKYSIAEGNDAKKFKIVEETGVIKVS----GDIDREEV-ASYRLKVRAQDQGLPPQVA 1361 Query: 777 DVRVEILVTDVNDNAP 792 D V+I VTDVNDN+P Sbjct: 1362 DTVVDIEVTDVNDNSP 1377 Score = 68.5 bits (160), Expect = 7e-11 Identities = 76/313 (24%), Positives = 122/313 (38%), Gaps = 36/313 (11%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEG---HTGKDCADST----GPPWR-FGGDGML--- 1364 +C+++PC G +C D + Y C C + H D T G R F GD + Sbjct: 1728 KCATSPCAPGYKCKDFPEGYQCKCVDATKCHMDTTGCDDTSCIKGNNARTFNGDSYIRYR 1787 Query: 1365 ---SFNPLLRPIQLPWLNALSIRTR-----QRDAFVMSIQLKSGLLHYSYNGETMYLPMA 1416 +F+ R I L S T Q D ++ I L + + + + + Sbjct: 1788 LKETFDQPSRSIGLALKTVKSEGTLVFAAGQYDYSILEISKGFIQLRFDFGPGVVSIDWS 1847 Query: 1417 TLSDGAWHRIEIKWLGTDISVTVDYGLRTV------LMPMLANKIQGQYIG-KILIGGLD 1469 ++DG WH + ++ G +VT+DYG M +L Y G K+L + Sbjct: 1848 PVNDGKWHHVAVERQGNHATVTLDYGKHQASGKSPGRMRILNLDGNSIYFGAKVLNSRIK 1907 Query: 1470 TTAGLLASDVGFFEGCIQDVRI-GTAQSLLNRPTVR----ENVRDGCQSRADCML-SICP 1523 + G F+GC+Q++ + G + T N GC++ C CP Sbjct: 1908 RSEGQGVIVENGFKGCMQNLNVNGKDLPMTGSNTYASGYPSNAERGCRTSGACQRPQACP 1967 Query: 1524 PYSKCVTSWDSSTCTCEAGRVGPQCVS--ACELGPCGAARCVPDQTPKGYSCACE-PGYT 1580 S+C+ ++ C C G GP C + C PC D++ GYS + P Sbjct: 1968 LASRCIETFTDRRCECLPGHSGPDCKAYIKCSGEPCQNRGVCVDKS-DGYSSMYDGPQVP 2026 Query: 1581 LTTSGCIESGKEE 1593 +S + S EE Sbjct: 2027 KRSSSLMSSSDEE 2039 Score = 33.9 bits (74), Expect = 1.9 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 3/55 (5%) Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT--LTTSGC 1586 S +CTC+ G + C PC D P+GY C C + T+GC Sbjct: 1711 SHSCTCQDKNRGCGAIQKCATSPCAPGYKCKD-FPEGYQCKCVDATKCHMDTTGC 1764 >SB_45916| Best HMM Match : Cadherin (HMM E-Value=0) Length = 1774 Score = 341 bits (838), Expect = 5e-93 Identities = 265/805 (32%), Positives = 384/805 (47%), Gaps = 66/805 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV + NDH+P+F + E + GTTV +A D+D+G V Y L Sbjct: 898 LNVTNTNDHAPIFNQSFVPLFIPENTTVGTTVYHAQAYDRDLGTYGHVTYQ--------L 949 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P A D F ++ +G + SLDRE A Y+V V A+D + Sbjct: 950 IPGRAW-----------DTFAVNKTTGDIKVTRSLDRESNASYSVTVMASD------GKF 992 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + I V+I D ND YP FS + Y+V++ E+ S PV+ ++ A D D G+NS + Y+ Sbjct: 993 QAFLEIDVHIQDINDQYPVFSPQNYSVAISEE-SWVRLPVL-QVTAVDMDSGSNSQVTYS 1050 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIR 248 I+ GN+ FSID +G + + +TLD+E RS+ L ++A+D G P+ + + INI Sbjct: 1051 IVDGNSS--FSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINIT 1108 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P F + S++E+V G V+A DAD G NA+L+Y++ D+D V Sbjct: 1109 DENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADSGKNAKLSYSIPDED----VRKT 1164 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +D +G + G +DRE Y +V TD G PR A F P Sbjct: 1165 FAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRP 1224 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y V ++E GT +V + A D D + + Y I GN F I G I + Sbjct: 1225 QNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHIDSGNKESIFDIED----GTIVLN 1280 Query: 427 QPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 LD + +Y L + ATD+G D A+V I I D N+ P F + Y+ ++ ED Sbjct: 1281 GTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDT 1340 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 IGT VL V A+D D+G NA + Y + + +++ + F +N TGAI+T LD E Sbjct: 1341 SIGTQVLSVYASDKDLGSNAHVQYFIIASANDDI----KRVFDVNKTTGAISTTSNLDFE 1396 Query: 543 TMSG-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + + + V ARD G P+L T VEI V DVNDN PVF ++ E+ V ++V Sbjct: 1397 SANNRFQFQVEARDNGKPALYSRTTVEIMVTDVNDNRPVFVGLPRDISVNENLPVKSTVL 1456 Query: 602 QVGATDADVGLNGRIHYELDPKDREEG-------SFVIDPASGVIRTNKALDRESVATHD 654 A D D G N + Y + G +F I+ +G I T K LDRE++A + Sbjct: 1457 IAHAHDEDSGSNSDVRYNITHTYGSRGDIHPDDRTFDIETVTGRIFTAKQLDRENIAYYI 1516 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L A D G + + I++ D ND+ P I E+SP+ TTI A+D Sbjct: 1517 LVLKACDLGRSRLCTNANITIRLRDKNDNRPALYLP-KQVNIREDSPVNTTIFTAYANDS 1575 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQ----GSDKAELVTMVDLDYESPRKKYELVIRAA 770 D G NA + Y IK D++ L D L LD E +Y++ I A Sbjct: 1576 DTGENARIIYDIKNVTDNHGHVLNPYSIFGIKPDSGRLFINRPLDRERV-SRYDVTIEAR 1634 Query: 771 S---PPLWNDVRVEILVTDVNDNAP 792 P + V I+V DVNDN P Sbjct: 1635 DGEITPHSSQGTVAIVVDDVNDNNP 1659 Score = 318 bits (782), Expect = 3e-86 Identities = 224/732 (30%), Positives = 344/732 (46%), Gaps = 47/732 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND PVF Q Y ++ E + VL + A D D G N++V Y+I Sbjct: 1000 VHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIV------- 1052 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D F ID +G ++ +LD E + + V+A D P Sbjct: 1053 ---DGNSS-----------FSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVS- 1097 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 A + +NI D+NDN P F +++Y S+ ED++ V ++A DAD G N+ + Y+ Sbjct: 1098 RDYAYVTINITDENDNNPVFDKRSYNFSITEDVA--KGTVFGFVRANDADSGKNAKLSYS 1155 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I + + F++D ++G++S+V +D E+ Y V+ D GS R + + ++DV Sbjct: 1156 IPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDV 1215 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + +SE +G IV V A+D D G NA +TY + +GN + Sbjct: 1216 NDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHID----SGNKE--SI 1269 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFMP 368 D G + +G LDRE +Y L + ATD G+PP+ + A F Sbjct: 1270 FDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNA 1329 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE---ITGGNTRGRFSITSQNGRGLITV 425 Y V ++ED GT V+++ A+D D + H + I N + G I+ Sbjct: 1330 SVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAIST 1389 Query: 426 AQPLDFKQ-ERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDA 482 LDF+ R+ V A D+G + V+I +TD N+ PVF P SV E+ Sbjct: 1390 TSNLDFESANNRFQFQVEARDNGKPALYSRTTVEIMVTDVNDNRPVFVGLPRDISVNENL 1449 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH-HDQQFVINPQTGAITTNKLLDR 541 P+ +TVL+ A D D G N+ + Y+++ + H D+ F I TG I T K LDR Sbjct: 1450 PVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSRGDIHPDDRTFDIETVTGRIFTAKQLDR 1509 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E ++ Y+L + A D G L ++ I + D NDN P NI ED+ V T++ Sbjct: 1510 ENIAYYILVLKACDLGRSRLCTNANITIRLRDKNDNRPALYLP-KQVNIREDSPVNTTIF 1568 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGS-------FVIDPASGVIRTNKALDRESVATHD 654 A D+D G N RI Y++ G F I P SG + N+ LDRE V+ +D Sbjct: 1569 TAYANDSDTGENARIIYDIKNVTDNHGHVLNPYSIFGIKPDSGRLFINRPLDRERVSRYD 1628 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + A DG P SS V I ++D+ND+ P S ++ ++ + D Sbjct: 1629 VTIEARDGEITPHSSQGTVAIVVDDVNDNNPKCNSSTSKVDYMISTREYESLLTLHVCDN 1688 Query: 715 DEGPNAVVHYSI 726 DEG N+VV ++I Sbjct: 1689 DEGNNSVVEFTI 1700 Score = 290 bits (711), Expect = 1e-77 Identities = 212/719 (29%), Positives = 338/719 (47%), Gaps = 53/719 (7%) Query: 98 ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157 AL+T LD E+ +R+ + + AT+ +L++ T+ +N+ + ND+ P F++ + Sbjct: 862 ALITAKPLDHEQNSRHELTITATN----TDTKLATVITVTLNVTNTNDHAPIFNQSFVPL 917 Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY 217 + E+ +V + +A D D+G + Y +I G F+++ +GD+ + ++LD Sbjct: 918 FIPENTTV--GTTVYHAQAYDRDLGTYGHVTYQLIPGRAWDTFAVNKTTGDIKVTRSLDR 975 Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 E SY + + A DG + ++ ++I+D+ND P F + ++SE + ++ Sbjct: 976 ESNASYSVTVMASDGKFQA---FLEIDVHIQDINDQYPVFSPQNYSVAISEESWVRLPVL 1032 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337 +V A D D G N+++TY++ D GN +IDP +G + LD E + L V Sbjct: 1033 QVTAVDMDSGSNSQVTYSIVD----GNSS--FSIDPNTGQIIVHRTLDFEVTRSFILRVQ 1086 Query: 338 ATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD- 394 A D G P + A F Y + ED GT + A DAD Sbjct: 1087 ARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADS 1146 Query: 395 -EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSD 451 ++ +L Y I + R F++ G ++V +D ++ Y V TD G R Sbjct: 1147 GKNAKLSYSIPDEDVRKTFAVDEITGN--LSVVGDIDRERTGIYSFVVVVTDHGSSPRVG 1204 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 A+V + + D N+ P+F YT + E +GT ++ V A D D+G NA ITY + S Sbjct: 1205 FAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHIDS- 1263 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-VPSLS-DTTDVEI 569 +++ + + + G I N LDRE M Y L + A D G P LS D V I Sbjct: 1264 --------GNKESIFDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVI 1315 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREE 627 ++ D+NDN P F +Y+ NI ED +GT V V A+D D+G N + Y + D + Sbjct: 1316 TIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIK 1375 Query: 628 GSFVIDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F ++ +G I T LD ES + A D G P S V I + D+ND+ PV Sbjct: 1376 RVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSRTTVEIMVTDVNDNRPV 1435 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-----KGGD---DSNSFSLE 738 F ++EN P+ +T+ AHD D G N+ V Y+I GD D +F +E Sbjct: 1436 FVGLPRDISVNENLPVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSRGDIHPDDRTFDIE 1495 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM 794 T G + T LD E+ Y LV++A L + + I + D NDN P + Sbjct: 1496 TVTG----RIFTAKQLDREN-IAYYILVLKACDLGRSRLCTNANITIRLRDKNDNRPAL 1549 Score = 222 bits (542), Expect = 4e-57 Identities = 174/625 (27%), Positives = 285/625 (45%), Gaps = 36/625 (5%) Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA-ELTYTMTDKDYTGNV 305 + +V D+ P F + + V E IG ++ ++ A ++ T+T + G Sbjct: 791 VLEVFDSKPAFRERHYSKEVLETTEIGEVLLGLRFSALGRFHRATSVSLTVTKGNKGGIF 850 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + + + T+ LD E ++++L +TAT+ D + T Sbjct: 851 MITPNVSREYAALITAKPLDHEQNSRHELTITATNT-DTKLATVITVTLNVTNTNDHAPI 909 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLI 423 F + + E+ GT V A D D H Y++ G F++ G I Sbjct: 910 FNQSFVPLFIPENTTVGTTVYHAQAYDRDLGTYGHVTYQLIPGRAWDTFAVNKTTGD--I 967 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 V + LD + Y +TV A+D G + ++I D N+ PVF Y+ ++ E++ Sbjct: 968 KVTRSLDRESNASYSVTVMASD-GKFQAFLEIDVHIQDINDQYPVFSPQNYSVAISEESW 1026 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + VL V+A D D G N+Q+TYS + + F I+P TG I ++ LD E Sbjct: 1027 VRLPVLQVTAVDMDSGSNSQVTYS---------IVDGNSSFSIDPNTGQIIVHRTLDFEV 1077 Query: 544 MSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ++L V ARD G P+L D V I++ D NDN PVF ++ Y +I ED GT Sbjct: 1078 TRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFG 1137 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A DAD G N ++ Y + +D + +F +D +G + +DRE + V D Sbjct: 1138 FVRANDADSGKNAKLSYSIPDEDVRK-TFAVDEITGNLSVVGDIDRERTGIYSFVVVVTD 1196 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G+ P+ +V ++++D+ND+ P+F T ISE + +GT I + AHD D GPNA+ Sbjct: 1197 HGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNAL 1256 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPLWND 777 + Y I G+ + F +E +V LD E +Y L I A P L D Sbjct: 1257 ITYHIDSGNKESIFDIE------DGTIVLNGTLDRE-VMDQYTLGILATDNGEPPQLSRD 1309 Query: 778 VRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSG 834 + ++ + D+NDN P N +D V A D D+ +QY I++ Sbjct: 1310 PAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIAS 1369 Query: 835 NNANL---ILLNETTGSMTLSPQLN 856 N ++ +N+TTG+++ + L+ Sbjct: 1370 ANDDIKRVFDVNKTTGAISTTSNLD 1394 Score = 216 bits (528), Expect = 2e-55 Identities = 166/583 (28%), Positives = 282/583 (48%), Gaps = 53/583 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ P+F Q Y + EG S GT ++ + A D+DIG NA + Y I D+ Sbjct: 1210 VQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHI-----DSG 1264 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N E +F I+ G ++ +LDRE + +YT+ + ATD P +L Sbjct: 1265 NKES--------------IFDIE--DGTIVLNGTLDREVMDQYTLGILATDNGEP--PQL 1306 Query: 131 SSTATIHVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S I V I+D NDNYP+F+ Y+V++ ED S+ + + A+D D+G+N+ ++Y Sbjct: 1307 SRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQ--VLSVYASDKDLGSNAHVQY 1364 Query: 190 AIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI 245 II + + F ++ +G +S LD+E + ++ + A+D G P+ + T + I Sbjct: 1365 FIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSRTTVEI 1424 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGN 304 + DVNDN P F SV+EN+P+ +++ A+D D G N+++ Y +T G+ Sbjct: 1425 MVTDVNDNRPVFVGLPRDISVNENLPVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSRGD 1484 Query: 305 V---DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + D I+ +G ++T+ QLDRE A Y L++ A D G A Sbjct: 1485 IHPDDRTFDIETVTGRIFTAKQLDRENIAYYILVLKACDLGRSRLCTNANITIRLRDKND 1544 Query: 362 XX-XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-----GNTRGRFS 413 ++P Q V + ED P T + T A D+D E+ R+ Y+I G+ +S Sbjct: 1545 NRPALYLPKQ--VNIREDSPVNTTIFTAYANDSDTGENARIIYDIKNVTDNHGHVLNPYS 1602 Query: 414 ITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470 I + G + + +PLD ++ RY +T+ A D S V I + D N+ P Sbjct: 1603 IFGIKPDSGRLFINRPLDRERVSRYDVTIEARDGEITPHSSQGTVAIVVDDVNDNNPKCN 1662 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 ++ ++L + D+D G N+ + ++++ +++ + +F ++ Sbjct: 1663 SSTSKVDYMISTREYESLLTLHVCDNDEGNNSVVEFTIARVVTDSEC---EGRFEVSSNG 1719 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 T L+ Y +TVT RD G P L+ T DV ++VV+ Sbjct: 1720 TLYNTVPLVHA---CKYTITVTVRDWGEPRLTGTCDVIVNVVE 1759 Score = 140 bits (338), Expect = 2e-32 Identities = 125/416 (30%), Positives = 198/416 (47%), Gaps = 29/416 (6%) Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F Y+ V E IG +L + S +G + T S+S ++ + F+I Sbjct: 799 PAFRERHYSKEVLETTEIGEVLLGLRF--SALGRFHRAT-SVSLTVTK---GNKGGIFMI 852 Query: 527 NPQTG----AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 P A+ T K LD E S + LT+TA + L+ V ++V + ND+ P+F Sbjct: 853 TPNVSREYAALITAKPLDHEQNSRHELTITATNTDT-KLATVITVTLNVTNTNDHAPIFN 911 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Q I E+ VGT+V A D D+G G + Y+L P R +F ++ +G I+ Sbjct: 912 QSFVPLFIPENTTVGTTVYHAQAYDRDLGTYGHVTYQLIP-GRAWDTFAVNKTTGDIKVT 970 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 ++LDRES A++ + +A DG + + + + I+DIND PVF + ISE S + Sbjct: 971 RSLDRESNASYSVTVMASDGKF---QAFLEIDVHIQDINDQYPVFSPQNYSVAISEESWV 1027 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 + ++ A D D G N+ V YSI G+ +SFS++ G +++ LD+E R Sbjct: 1028 RLPVLQVTAVDMDSGSNSQVTYSIVDGN--SSFSIDPNTG----QIIVHRTLDFEVTRS- 1080 Query: 763 YELVIRA---ASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817 + L ++A P L + V I +TD NDN PV F+ +D FG V Sbjct: 1081 FILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVR 1140 Query: 818 AYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 A DAD KL Y I + ++E TG++++ ++ + + V VTD Sbjct: 1141 ANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTD 1196 Score = 112 bits (269), Expect = 4e-24 Identities = 104/354 (29%), Positives = 161/354 (45%), Gaps = 40/354 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV--TA 67 +I V D ND+ PVF + SV E +TVL A D+D G N++V Y I + Sbjct: 1423 EIMVTDVNDNRPVFVGLPRDISVNENLPVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSR 1482 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 ++P+D F I+ +G + T LDRE +A Y +++KA D Sbjct: 1483 GDIHPDDR-------------TFDIETVTGRIFTAKQLDRENIAYYILVLKACDLG---R 1526 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 RL + A I + + D NDN P V++ ED V N I A D+D G N+ I Sbjct: 1527 SRLCTNANITIRLRDKNDNRPAL-YLPKQVNIREDSPV--NTTIFTAYANDSDTGENARI 1583 Query: 188 RYAIIG-----GNTQMQFSIDSL---SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 Y I G+ +SI + SG + + + LD E+V Y + I A+DG S+ Sbjct: 1584 IYDIKNVTDNHGHVLNPYSIFGIKPDSGRLFINRPLDRERVSRYDVTIEARDGEITPHSS 1643 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT---- 295 + I + DVNDN P+ +S + + S++ + D DEG N+ + +T Sbjct: 1644 QGTVAIVVDDVNDNNPKCNSSTSKVDYMISTREYESLLTLHVCDNDEGNNSVVEFTIARV 1703 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 +TD + G ++ +G +Y + L KY + VT D G+P + T Sbjct: 1704 VTDSECEGRFEV-----SSNGTLYNTVPLVH--ACKYTITVTVRDWGEPRLTGT 1750 Score = 50.0 bits (114), Expect = 3e-05 Identities = 48/214 (22%), Positives = 94/214 (43%), Gaps = 10/214 (4%) Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSL 737 ++ DS P F + + E + IG + +R A V ++ G+ F + Sbjct: 793 EVFDSKPAFRERHYSKEVLETTEIGEVLLGLRFSALGRFHRATSVSLTVTKGNKGGIFMI 852 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP--LWNDVRVEILVTDVNDNAPVM- 794 + A L+T LD+E ++EL I A + L + V + VT+ ND+AP+ Sbjct: 853 TPNVSREYAALITAKPLDHEQ-NSRHELTITATNTDTKLATVITVTLNVTNTNDHAPIFN 911 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLS 852 + F +F + AYD D+ + Y+++ G + +N+TTG + ++ Sbjct: 912 QSFVPLFIPENTTVGTTVY-HAQAYDRDLGTYGHVTYQLIPGRAWDTFAVNKTTGDIKVT 970 Query: 853 PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 L+ ++ V +DG + +A +++ V + Sbjct: 971 RSLDRESNASYSVTVMASDG--KFQAFLEIDVHI 1002 >SB_5763| Best HMM Match : Cadherin (HMM E-Value=0) Length = 674 Score = 332 bits (817), Expect = 2e-90 Identities = 207/604 (34%), Positives = 324/604 (53%), Gaps = 33/604 (5%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 SG ++ + LDRE Y + V A + + D +T +H+ + D D+ P F+ + Sbjct: 78 SGDIIVDSPLDREFKNVYILNVTAANIVAGAQD---TTTQVHITVTDVIDDKPYFNSSSL 134 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215 TV + E+ S+ N + KI A D D+G I Y+I G+ F+ID+++G++ V L Sbjct: 135 TVKLSENASIGTN--VTKITALDKDIG--DTISYSIANGDPYGLFTIDNVTGEIRTVAEL 190 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D E V Y L ++A+D + S+ ++++ + DVNDN P F + E P G S Sbjct: 191 DRENVTQYELFVQAKDSVNLV-SDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTS 249 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQL 334 I++V+A DAD G NA + Y++ + NV +T++ +G + S QLDRE + + Sbjct: 250 ILQVKAIDADIGDNAAVLYSIVE-----NVTDYVTVNAITGVISLGSSQLDREVEEYFNF 304 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 + ATD G P +S+TA+ F Y + E++P GTPV+ +TA+D D Sbjct: 305 TIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKD 364 Query: 395 --EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRS 450 + +L Y + G RF+I G IT +PL+ ++ Y LT+ A DS R Sbjct: 365 VGTNAKLSY-VLSGVLYTRFAIDPDTGN--ITTREPLNREETGSYTLTLRAVDSAIRARE 421 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 T V I +TDAN++ P F + Y SV ED +G TV V+ TD D+ NA++ Y +SS Sbjct: 422 GTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISS 481 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 N ++ F +N TG I+T LDRE + Y L +TA+D G+P+L T V I+ Sbjct: 482 --GNTSL-----MFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMIT 534 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE---- 626 + DVNDN+P+F + +Y + E + T V QV ATD D G NG+ Y++ D + Sbjct: 535 IEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFY 594 Query: 627 -EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 +G F +D +GV+ + LDRE + + L +A D G P SS+V V+I + D+ND+ P Sbjct: 595 IDGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLP 654 Query: 686 VFES 689 + ++ Sbjct: 655 ILQT 658 Score = 295 bits (724), Expect = 3e-79 Identities = 204/601 (33%), Positives = 303/601 (50%), Gaps = 30/601 (4%) Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +SGD+ + LD E Y L + A + + ++ TTQ+ I + DV D+ P F +S Sbjct: 77 VSGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLTV 136 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 +SEN IG ++ ++ A D D G ++Y++ + D G TID +G + T +L Sbjct: 137 KLSENASIGTNVTKITALDKDIGDT--ISYSIANGDPYGL----FTIDNVTGEIRTVAEL 190 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE +Y+L V A D + MPG Y +E E+ P GT Sbjct: 191 DRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPG-YTIEYWEESPEGTS 249 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV-AQPLDFKQERRYVLTV 441 ++ + A DAD ++ + Y I T +T G+I++ + LD + E + T+ Sbjct: 250 ILQVKAIDADIGDNAAVLYSIVENVTD---YVTVNAITGVISLGSSQLDREVEEYFNFTI 306 Query: 442 SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 ATDSG +S TA V I + D N+ +PVF N Y A V E+ P GT VLVV+A+D DVG Sbjct: 307 RATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVG 366 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA+++Y LS + +F I+P TG ITT + L+RE Y LT+ A D + Sbjct: 367 TNAKLSYVLSGVLYT--------RFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIR 418 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 + TT V I+V D ND+ P F Q Y ++ ED VG +V +V TD D+ N R+ Y Sbjct: 419 AREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYY 478 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + + F ++ +G+I T LDRE A++ L A D G P S V I IED Sbjct: 479 ISSGNTSL-MFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIED 537 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE- 738 +ND+ P+F + E+ + T + ++ A DPDEG N Y I GD + F ++ Sbjct: 538 VNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDG 597 Query: 739 TRQGSDKAELVTMV-DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794 Q +K ++T LD E Y LV+ A P L + V V I V D+NDN P++ Sbjct: 598 VFQMDNKTGVLTRTRPLDRED-TSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPIL 656 Query: 795 K 795 + Sbjct: 657 Q 657 Score = 274 bits (672), Expect = 7e-73 Identities = 192/577 (33%), Positives = 279/577 (48%), Gaps = 41/577 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D D P F + E AS GT V + A D+DIG + Y+I D Sbjct: 117 ITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSI--ANGDPY 172 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F ID +G + T A LDRE V +Y + V+A D + VSD L Sbjct: 173 G-----------------LFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLL 215 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + V + D NDN P FS YT+ E+ + I ++KA DAD+G N+A+ Y+ Sbjct: 216 K----VVVQVEDVNDNPPVFSMPGYTIEYWEE--SPEGTSILQVKAIDADIGDNAAVLYS 269 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ N ++++++G +SL + LD E + IRA D G PS+S+T + I + D Sbjct: 270 IV-ENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVD 328 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN+P F + + V EN P G ++ V A D D G NA+L+Y ++ YT Sbjct: 329 INDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYT-----RF 383 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 IDP +G + T L+RE Y L + A D R T F Sbjct: 384 AIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQS 443 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD-EDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y + ED G V + TD D DN R+ Y I+ GNT FS+ G+I+ Sbjct: 444 GYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNETT--GIISTTS 501 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD +Q Y L ++A D G V I I D N+ P+F + Y ++ E + Sbjct: 502 TLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLK 561 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V+ V ATD D G N Q TY +++ +++ V + D F ++ +TG +T + LDRE S Sbjct: 562 TQVVQVIATDPDEGANGQFTYKITAGDTDD-VFYIDGVFQMDNKTGVLTRTRPLDREDTS 620 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 Y L V A D G P+LS + V I+V+D+NDN P+ + Sbjct: 621 FYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQ 657 Score = 204 bits (499), Expect = 6e-52 Identities = 155/474 (32%), Positives = 229/474 (48%), Gaps = 26/474 (5%) Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDAN 463 G+ G S + G I V PLD + + Y+L V+A + +G + T V I +TD Sbjct: 64 GDGGGGEDTDSGDVSGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVI 123 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 + P F ++ T + E+A IGT V ++A D D+G I+YS+++ Sbjct: 124 DDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSIAN-------GDPYGL 174 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F I+ TG I T LDRE ++ Y L V A+D V +SD V + V DVNDN PVF Sbjct: 175 FTIDNVTGEIRTVAELDRENVTQYELFVQAKDS-VNLVSDLLKVVVQVEDVNDNPPVFSM 233 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 YT E++ GTS+ QV A DAD+G N + Y + + ++ +GVI Sbjct: 234 PGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSI--VENVTDYVTVNAITGVISLGS 291 Query: 644 A-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 + LDRE + A D G P +SST V IK+ DIND+ PVF + Y+ EN P Sbjct: 292 SQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPA 351 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 GT + + A D D G NA + Y + G + F+++ D + T L+ E Sbjct: 352 GTPVLVVTASDKDVGTNAKLSYVLSGVLYTR-FAIDP----DTGNITTREPLNREETGS- 405 Query: 763 YELVIRAASPPLW---NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 Y L +RA + RV I VTD ND+ P F+ +D GRV Sbjct: 406 YTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATT 465 Query: 820 DADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D D+ D +++Y I SGN + + +NETTG ++ + L+ T+ ++ D Sbjct: 466 DEDINDNARVRYYISSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKD 519 Score = 127 bits (307), Expect = 1e-28 Identities = 84/257 (32%), Positives = 123/257 (47%), Gaps = 30/257 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH P F Y SVRE G TV + TD+DI NA V Y I + Sbjct: 428 ITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLM 487 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ++ +G + T ++LDRE+ A YT+++ A D P L Sbjct: 488 -------------------FSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPA---L 525 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S ++ + I D NDN P FS+ Y V++ E + + + ++ ATD D GAN Y Sbjct: 526 ESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQ--VVQVIATDPDEGANGQFTYK 583 Query: 191 IIGGNTQMQFSIDSL------SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I G+T F ID + +G ++ + LD E Y LV+ A+D G P+ S++ + Sbjct: 584 ITAGDTDDVFYIDGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVN 643 Query: 245 INIRDVNDNAPRFYTSL 261 I + D+NDN P T + Sbjct: 644 ITVLDMNDNLPILQTPM 660 Score = 41.1 bits (92), Expect = 0.012 Identities = 35/162 (21%), Positives = 66/162 (40%), Gaps = 4/162 (2%) Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW---NDVRVEILV 784 GG +T G +++ LD E + Y L + AA+ +V I V Sbjct: 61 GGCGDGGGGEDTDSGDVSGDIIVDSPLDREF-KNVYILNVTAANIVAGAQDTTTQVHITV 119 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844 TDV D+ P + ++ ++ A D D+ D + Y I +G+ L ++ Sbjct: 120 TDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGLFTIDN 179 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 TG + +L+ + V D VN + ++++ V++ Sbjct: 180 VTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLLKVVVQV 221 >SB_47886| Best HMM Match : Cadherin (HMM E-Value=0) Length = 679 Score = 329 bits (809), Expect = 2e-89 Identities = 233/717 (32%), Positives = 342/717 (47%), Gaps = 90/717 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+LD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I Sbjct: 24 VNILDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 75 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 76 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 121 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST + + + D NDN P + VS+ I ATD D GANSA+ Y+ Sbjct: 122 NSTTAVAIQVGDANDNPPVIQDAVIQVSL--------------ISATDGDAGANSALTYS 167 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN + FSI++ +G +S+ K LD E Y L + AQDGG P ++TT ++I + D Sbjct: 168 IAAGNEEGVFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVVIQVGDA 227 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P ++ Q S+SE I + V A D D G N L Y++ + G+ + Sbjct: 228 NDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFQIK-- 284 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 D SG + +G L + Y ++V TDGG P + A Sbjct: 285 -DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------ 337 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQ 427 Y+V + E E V+ L ++ H+ ++GGN S+ S NG L + Sbjct: 338 YDVSVLEGE-ANVQVMDLKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGST 390 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 PLD + ++VL +S T+ G V +N+ D N+ P+F++ + SV E +GT Sbjct: 391 PLDRETAAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV 450 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 L VSATD D G N+ +TYS+ A + + F IN +TGAI+ K LDRET Y Sbjct: 451 FLTVSATDGDAGSNSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQY 503 Query: 548 LLTVTARDGGVPSLSDTT--------------------------DVEISVVDVNDNEPVF 581 LTV A+DGG P L+ TT +V ++V+D+ND P+F Sbjct: 504 TLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSEVTVNVLDINDETPLF 563 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 + + ++ E +GT V ATD D G N + Y + EEG F I+ +G I Sbjct: 564 QSPSFNVSVNEIERLGTVFLTVLATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISV 622 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV + + +SE Sbjct: 623 AKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 679 Score = 297 bits (729), Expect = 8e-80 Identities = 226/712 (31%), Positives = 340/712 (47%), Gaps = 81/712 (11%) Query: 120 TDQASPVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 +++ S +S+ LS A + VNI+D ND P F ++ VSV+E + V + ATD Sbjct: 5 SNKNSLISEDLSYIALQVTVNILDINDETPLFQSPSFNVSVNEIERL--GTVFLTVSATD 62 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 D GANSA+ Y+I GN + FSI++ +G +S+ K LD E Y L + AQDGG P + Sbjct: 63 GDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLN 122 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 +TT + I + D NDN P ++ Q S+ + A D D G N+ LTY++ Sbjct: 123 STTAVAIQVGDANDNPPVIQDAVIQVSL------------ISATDGDAGANSALTYSIA- 169 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 GN + +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 170 ---AGNEEGVFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVVIQVGD 226 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416 +V L+E TPV T+ A+D D + RL Y I G G F I Sbjct: 227 ANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQI-K 284 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPY 474 + G I++A L + Q Y++ V+ TD G + AMV I++T P N Y Sbjct: 285 DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PKPRNLTY 338 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 SV E V+ + +S ++ T+ SS F IN T Sbjct: 339 DVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDSS----------GSMFSIN-GTNLR 386 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + LDRET + ++L ++ +GG ++ V ++V+D+ND P+F+ + ++ E Sbjct: 387 VGSTPLDRETAAQHVLDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEI 444 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 +GT V ATD D G N + Y + EEG F I+ +G I K LDRE+ + Sbjct: 445 ERLGTVFLTVSATDGDAGSNSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQY 503 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV--------------------------F 687 L +A DGG PP +ST V I++ D ND+PPV F Sbjct: 504 TLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSEVTVNVLDINDETPLF 563 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 +S ++E +GT + A D D G N+ + YSI G++ FS+ + G+ Sbjct: 564 QSPSFNVSVNEIERLGTVFLTVLATDGDAGANSALTYSIAAGNEEGFFSINNKTGA---- 619 Query: 748 LVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796 + LD E+ R +Y L + A PPL + V I V D NDN PV++D Sbjct: 620 ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 670 Score = 231 bits (565), Expect = 6e-60 Identities = 195/664 (29%), Positives = 297/664 (44%), Gaps = 74/664 (11%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 Q+ +NI D+ND P F + F SV+E +G + V A D D G N+ LTY++ Sbjct: 21 QVTVNILDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA---- 76 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 GN + +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 77 AGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAND 136 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 +V L ++ T DA ++ L Y I GN G FSI N G Sbjct: 137 NPPVIQDAVIQVSL----------ISATDGDAGANSALTYSIAAGNEEGVFSIN--NKTG 184 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479 I+VA+ LD + +Y LTV A D G + T V I + DAN+ PV ++A S+ Sbjct: 185 AISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVVIQVGDANDNPPVIQDAVIQVSLS 244 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E A I T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ +L Sbjct: 245 ETAAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGML 297 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 + Y++ V DGG P+L V V+DV P + Y +++E Sbjct: 298 SYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKPRNLTYDVSVLEGE-ANVQ 350 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V + ++ ++G D GS + + + LDRE+ A H L Sbjct: 351 VMDLKPAESHFNVSGGNFTFFD----SSGSMFSINGTNLRVGSTPLDRETAAQHVLDISL 406 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 +GGT V V + + DIND P+F+S ++E +GT + A D D G N Sbjct: 407 TEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGSN 464 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 + + YSI G++ FS+ + G+ + LD E+ R +Y L + A PPL + Sbjct: 465 SALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNS 519 Query: 777 DVRVEILVTDVNDNAPVMKDFQI------IFNNYKDCFPVGPFGRVPAY----------- 819 V I V D NDN PV++D I + N D P + P++ Sbjct: 520 TTAVAIQVGDANDNPPVIQDAVIQVSLSEVTVNVLDINDETPLFQSPSFNVSVNEIERLG 579 Query: 820 -----------DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 DA L Y I +GN +N TG+++++ QL+ T+ V Sbjct: 580 TVFLTVLATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVM 639 Query: 869 VTDG 872 DG Sbjct: 640 AQDG 643 >SB_51779| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3610 Score = 304 bits (746), Expect = 7e-82 Identities = 280/983 (28%), Positives = 441/983 (44%), Gaps = 88/983 (8%) Query: 9 QQINVLDCND-HSPVFEMQQYEASVREGASSGTTVLTLKATDQDI----------GKNAE 57 Q + V+D P+FE Y SVRE A+ GTT+ ++A Q+ NA+ Sbjct: 1621 QTLVVIDVTTVEPPMFERHLYNISVRENAAVGTTIGQIRAVSQNNRPIMYQPLHENPNAK 1680 Query: 58 VEYTIELVTADTLNPEDAXXXXXXXXXXVQDV--FRIDGRSGALLTRASLDREKVARYTV 115 E IE+ T + +QD F ID + G + DRE+ +RY++ Sbjct: 1681 EEIGIEIDTGSIVT-SSKLDYESVNNYELQDYQKFTIDTQRGTIRNAVVFDREEESRYSL 1739 Query: 116 LVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK 175 ATD +P S+ + ++++D ND P F +K SV ED + + + K Sbjct: 1740 TAIATDAGTPP---FSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSS--VYKAV 1794 Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSI------DSLSGDVSLVKTLDYEQVRSYRLVIRA 229 D+D+ ++++ + I GGN + +F + S G V ++ LDYE R ++L + Sbjct: 1795 ILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQREFKLRLTI 1854 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-V 288 DG + S+ L I + D NDNAP F +++ S+ E P G S+V V A D D V Sbjct: 1855 SDGKT---SDFGFLTIKVTDANDNAPLFSKLVYEVSLREESPAGTSVVTVSAIDIDSPPV 1911 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRS 347 +TY++ D G + I +G + LDRE Y V A+DG + R+ Sbjct: 1912 QEAITYSI---DKRG--EQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGRA 1966 Query: 348 ATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406 F P Y L E+ GT V + A D D+ N GG Sbjct: 1967 EVMVTLVDINDQAP----FFPNPPYYAALFENRAIGTNVTVMQAIDNDDPN------AGG 2016 Query: 407 NTRGRFSITSQNG--------RGLITVAQPLDFK--QERRYVLTVSATDSG--GRSDTAM 454 NT+ +S+ NG GL+T + +D + QE + +TV ATD G S T + Sbjct: 2017 NTKIIYSLEDNNGGYVTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQPALSGTTV 2076 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 +Q+ D N++ P F Y ASV E G V V ATD D G N + Y + N Sbjct: 2077 LQVFFEDENDHKPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQ--GN 2134 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVV 572 E A F I P+TG + + +LD E+ Y L V D G+P L + V +++ Sbjct: 2135 EPYA-----FFIEPRTGVVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNIT 2189 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 D N + P F Q+++ A++ ED +G SV + ATD D H L EE F I Sbjct: 2190 DDNTHPPRFAQKVHEASVREDVPLGYSVLTIKATDIDTV--DSFHRFLISSGDEENMFTI 2247 Query: 633 -----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 + + +I LDRE + +++ V D T QS IV I + D ND+ P F Sbjct: 2248 TESESEKMTAIITVRGKLDRERKSFYNMIVVVND--TSGQSDECIVKITVTDANDNGPHF 2305 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSL-ETRQGSDK 745 + + ++ EN + I A DPD N +++ S+ F + ++ S+ Sbjct: 2306 QPSYFSGFVRENIDSEQFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNT 2365 Query: 746 AELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 A++ D E Y+L++ A+ P +WN + + V DVN++ P+ + II N Sbjct: 2366 AQVFAYGTFDREL-TPFYKLLVNASDSGRPAMWNHTYIYVDVLDVNEHEPIDGNNTIIVN 2424 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQ-YRILSGNNANLILLNETTGSMTLSP--QLNTNV 859 F G GR D D + Y++ S + + +N TG++T SP L V Sbjct: 2425 ALDGAFAGGVIGRPYYQDDDYNGDINVYKMTSQSPGAYLDMNSATGAITASPGIPLGEYV 2484 Query: 860 PKLATME-VSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFI 917 K + +E V D ++ ++ VR ++ + +L S T+RL DM + + Sbjct: 2485 VKASVIESVPRQDKAPKTVETTTRVVVRNVSTQAVLASTTMRLTDMRKPGLFVQDYYYTV 2544 Query: 918 DG-LAAIIPCPKENIYIFSVQDD 939 + LA I P++++ IF +Q + Sbjct: 2545 ERLLAGIFGVPRDHVVIFGIQQN 2567 Score = 211 bits (516), Expect = 5e-54 Identities = 231/881 (26%), Positives = 376/881 (42%), Gaps = 116/881 (13%) Query: 11 INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I+V+D ND+ P F + + + + + +G+ VL+L A D D +N EV + I Sbjct: 995 ISVIDVNDNVPRFTGITRIYKRINKNSLNGSPVLSLNALDLDYERNGEVGFQIV------ 1048 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D F I+ + T +L++E Y V A D P + Sbjct: 1049 --PRDGP-------------FGINPVDEMIETTGNLNKES---YEFDVYAFDYGIPRLNS 1090 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + +HV + Y E + +I +KA + + I Y Sbjct: 1091 TTIPMVVHVAEVPPIFEVLDNDHNMYRFETAE--TSHGGELIGTVKAVSY---SKALIAY 1145 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I GN + F I +L+G++ ++YE Y L + A + ++I+++ Sbjct: 1146 EITSGNVRNSFKIGTLTGEIRHNNFMNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLK 1205 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-----AELTYTMTDKDYTG 303 ++NDN PRF SLF +V+E+VP+G SI++V A D D + ELTY++ + D Sbjct: 1206 NINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTYSIDNTDM-- 1263 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 I P +G + + LD E + L+V D G P + Sbjct: 1264 -----FAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLLPVNDNS 1318 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F Y +++E G + +TATD D D + Y I G + G + I +G + Sbjct: 1319 PVFAQSNYAFQISETAEVGNELAFVTATDRDGD-PITYTIEGDS--GPYIIDPSSGIITL 1375 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA----SVF 479 + P++ + Y V ATD G + T V ++I D NN+ P F N ++ + Sbjct: 1376 SREAPVNVWE---YNFKVKATD-GIFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIA 1431 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P G ++ V ATD D G+N ++ Y L + D F I+ TG I T L Sbjct: 1432 ENLPSGQVLMQVQATDEDRGLNGEVEYEL-------VIGFTD--FSIDNTTGVIKTRYPL 1482 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVE-----ISVVDVNDNEPVFKQQLYTANIMEDA 594 DRE S + V A+DGG ++ +SVVD NDN P+F Y +++ + A Sbjct: 1483 DRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKA 1542 Query: 595 LVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRES---- 649 VG S+ +V A D D G N ++ Y ++P D+ F I+ +G++ L + Sbjct: 1543 PVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDK----FAIEKTTGIVTVKTDLSSFTGFVT 1598 Query: 650 --VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 V + + + + G + +V I + + PP+FE + EN+ +GTTIG Sbjct: 1599 LQVQSSNPVPITVSVGEDDRDRQTLVVIDVTTV--EPPMFERHLYNISVRENAAVGTTIG 1656 Query: 708 EIRA---------HDP-DEGPNAVVHYSIK---GG-----------------DDSNSFSL 737 +IRA + P E PNA I+ G D F++ Sbjct: 1657 QIRAVSQNNRPIMYQPLHENPNAKEEIGIEIDTGSIVTSSKLDYESVNNYELQDYQKFTI 1716 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 +T++G+ + +V D + ES + A +PP V V+I V D ND P D Sbjct: 1717 DTQRGTIRNAVV--FDREEESRYSLTAIATDAGTPPFSTQVFVKIDVLDANDQPPSFPDK 1774 Query: 798 QIIFNNYKDCFPVG-PFGRVPAYDAD-VTDKLQYRILSGNN 836 + + +D P+G + D+D V D + +SG N Sbjct: 1775 NLQASVREDA-PIGSSVYKAVILDSDMVFDTSMHFFISGGN 1814 Score = 209 bits (511), Expect = 2e-53 Identities = 202/686 (29%), Positives = 321/686 (46%), Gaps = 71/686 (10%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIR-AQDGGSPSRSNTTQLLINIRDVNDNAPRF- 257 FSID + GD+ + K LD+E+ SY L +R A+ GS R ++I++ DVNDN PRF Sbjct: 950 FSIDEI-GDIRVAKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVPRFT 1008 Query: 258 -YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 T +++ +++N G ++ + A D D N E+ + + +D P I+P Sbjct: 1009 GITRIYKR-INKNSLNGSPVLSLNALDLDYERNGEVGFQIVPRDG------PFGINPVDE 1061 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP---GQYEV 373 + T+G L++E+ Y+ V A D G P ++T + Y Sbjct: 1062 MIETTGNLNKES---YEFDVYAFDYGIPRLNSTTIPMVVHVAEVPPIFEVLDNDHNMYRF 1118 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK- 432 E AE G + T+ A + + YEIT GN R F I + G I ++++ Sbjct: 1119 ETAETSHGGELIGTVKAVSYSK-ALIAYEITSGNVRNSFKIGTLTGE--IRHNNFMNYEI 1175 Query: 433 QERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 E Y LTV+A++ G V I++ + N+ P F + +T +V ED P+GT++L Sbjct: 1176 HENVYNLTVTASELIPRGHQTEIPVIIHLKNINDNYPRFTKSLFTTAVNEDVPVGTSILQ 1235 Query: 491 VSATDSDVGIN-----AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 V+ATD D + ++TYS+ + F I+P TG I+ LD E S Sbjct: 1236 VTATDCDCSKSCLCAPGELTYSID----------NTDMFAISPDTGVISPAVSLDYEMSS 1285 Query: 546 GYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 +L V D GG P++ + I+++ VNDN PVF Q Y I E A VG ++ V Sbjct: 1286 WVVLVVKVEDKGGSPNIMQSY-ANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVT 1344 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D I Y + + + G ++IDP+SG+I ++ +V ++ K A DG Sbjct: 1345 ATDRD---GDPITYTI---EGDSGPYIIDPSSGIITLSREAP-VNVWEYNFKVKATDG-- 1395 Query: 665 PPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 ++T V + I D N+ P F ES I+EN P G + +++A D D G N Sbjct: 1396 -IFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAENLPSGQVLMQVQATDEDRGLNG 1454 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-----PPLW 775 V Y + G FS++ G K T LD E K+Y +V+RA L+ Sbjct: 1455 EVEYELVIG--FTDFSIDNTTGVIK----TRYPLDRERTSKQY-IVVRAKDGGHRRNELF 1507 Query: 776 NDVR---VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRI 831 ++ + + V D NDN P+ + + + Y+ PVG RV A D D + Sbjct: 1508 RNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKA-PVGHSLVRVKAIDLDTGSNAKVEY 1566 Query: 832 LSGNNANLILLNETTGSMTLSPQLNT 857 ++ + +TTG +T+ L++ Sbjct: 1567 TFVEPSDKFAIEKTTGIVTVKTDLSS 1592 Score = 187 bits (455), Expect = 1e-46 Identities = 229/882 (25%), Positives = 387/882 (43%), Gaps = 101/882 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D N+H+P Y A+V + T ++T+ A+D D + + + V+ Sbjct: 94 LSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLD-KEEGNQQVLFQFVS---- 148 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 DA Q+ F+ID +G + + L Y + VKATD SP + Sbjct: 149 ---DADSSG-------QNRFQIDSSTGTITSTNLLAANN--EYKLTVKATDTGSPP---M 193 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S ++ V++I +F+E Y ++ E + V N V+ ++ AT +AI Y+ Sbjct: 194 ESQVSVTVSVITPITTPVKFAEANYAKTIQESL-VIGNSVL-QVTATGP-----AAITYS 246 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRD 249 I+GGN F ID +G +++ K LDYE ++SY L +RA + +P + + I + D Sbjct: 247 IVGGNKNDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTD 306 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN+P F L+ + V V +Y ++ V + Y + + Sbjct: 307 VNDNSPVFL--LYSNPTT---------VTVNSYTPEQTV----VFKARRFTYYVIYEKAL 351 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +D S T DR A+Y + + ATDGG +T T F Sbjct: 352 AVDADSESFGTVRYSDR---AEYTVALVATDGGG---KSTTTSLVIKVFNINEPPKFPQP 405 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 +YE + E++ GT + +TAT AD + L Y IT GN F + N +G+I++A+ L Sbjct: 406 KYEFSVPENKQVGTEIGAITATYADPNTLLKYSITRGNIDDTFCV---NSKGVISLAKAL 462 Query: 430 DFKQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 D E + T+ A S G S+ T +VQI + D N+ P+ E Y V ED GT V Sbjct: 463 D--SETKASFTLDAMVSHGTSNHTTVVQITVNDINDNWPIMEPV-YNVEVREDQ--GTIV 517 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + ++ ++ + + VA D NP + TNK + G Sbjct: 518 MASFVIFCIAAVHKHYR-RIARKTCHVKVARLD-----NPL--PVLTNKAISSYLAPGTE 569 Query: 549 L---TVTARDGGVP-----SLSDTTDV-EISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 L T DGGV ++ T D+ S+ VN + V LY A++ + V Sbjct: 570 LVKVVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVI--TLYLASVPYEFPVNFH 627 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V QV ATDAD G N + Y + E+G F I+ +G++ + L + H L A Sbjct: 628 VFQVIATDADSGSNAELTYAI-TGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKA 686 Query: 660 IDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 D G P + +ST+IV + + D+ P F L + E G + ++ Sbjct: 687 TDNGVPRRIGTSTIIVFVILADL---LPKFPVSPLIVNVKEGVLPGGRVTTVKMTS---- 739 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 + ++ Y I G+D F +++ G +L+ + +LDYE R + + I+ D Sbjct: 740 -SRLMTYRILEGNDEGYFRMDSLSG----DLLALKELDYEDVR-TFTMRIKGQDTDGNAD 793 Query: 778 -VRVEILVTDVNDNAPVMK---DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRIL 832 V + + + DVND +PV +++ + G P ++ YD D D+L + L Sbjct: 794 VVTLVVNLEDVNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFE-L 852 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 S + +++ G + + +N ++ + + V+V D + Sbjct: 853 SDEGERIFTIDD-EGQLIPTRSVN-DITEPLSFTVTVRDSAS 892 Score = 163 bits (395), Expect = 2e-39 Identities = 179/678 (26%), Positives = 293/678 (43%), Gaps = 70/678 (10%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID G + LD EK YT+ V+ + S R+ + +++ID NDN P+ Sbjct: 950 FSID-EIGDIRVAKPLDFEKQVSYTLTVREAESIGS-SPRVFDRVVV-ISVIDVNDNVPR 1006 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F+ T S+ +PV++ + A D D N + + I+ + F I+ + + Sbjct: 1007 FTGITRIYKRINKNSLNGSPVLS-LNALDLDYERNGEVGFQIVPRDG--PFGINPVDEMI 1063 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIRDVNDNAPRFYT-----SLFQ 263 L+ E SY + A D G P ++TT +++++ +V P F ++++ Sbjct: 1064 ETTGNLNKE---SYEFDVYAFDYGIPRLNSTTIPMVVHVAEV---PPIFEVLDNDHNMYR 1117 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 +E G I V+A + A + Y +T +GNV I +G + + Sbjct: 1118 FETAETSHGGELIGTVKAVSYSK---ALIAYEIT----SGNVRNSFKIGTLTGEIRHNNF 1170 Query: 324 LDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 ++ E Y L VTA++ F + + ED P G Sbjct: 1171 MNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLKNINDNYPRFTKSLFTTAVNEDVPVG 1230 Query: 383 TPVVTLTATDAD-------EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 T ++ +TATD D L Y I NT F+I+ G+I+ A LD++ Sbjct: 1231 TSILQVTATDCDCSKSCLCAPGELTYSI--DNT-DMFAISPDT--GVISPAVSLDYEMSS 1285 Query: 436 RYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 VL V D GG + NIT N+ +PVF + Y + E A +G + V+A Sbjct: 1286 WVVLVVKVEDKGGSPNIMQSYANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVTA 1345 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 TD D ITY++ + ++I+P +G IT ++ Y V A Sbjct: 1346 TDRD---GDPITYTIEGD---------SGPYIIDPSSGIITLSREAPVNVWE-YNFKVKA 1392 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVF----KQQLYTANIMEDALVGTSVSQVGATDAD 609 DG + TTDV + ++D N+++P F + I E+ G + QV ATD D Sbjct: 1393 TDG---IFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAENLPSGQVLMQVQATDED 1449 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS- 668 GLNG + YEL + F ID +GVI+T LDRE + + A DGG Sbjct: 1450 RGLNGEVEYELVIGFTD---FSIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNEL 1506 Query: 669 ----STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 + ++ + + D ND+ P+F + + +P+G ++ ++A D D G NA V Y Sbjct: 1507 FRNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEY 1566 Query: 725 SIKGGDDSNSFSLETRQG 742 + + S+ F++E G Sbjct: 1567 TFV--EPSDKFAIEKTTG 1582 Score = 161 bits (391), Expect = 7e-39 Identities = 220/860 (25%), Positives = 361/860 (41%), Gaps = 91/860 (10%) Query: 36 ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGR 95 AS+G L L + + N V +++ D + +A +F+I+ Sbjct: 606 ASTGVITLYLASVPYEFPVNFHV---FQVIATDADSGSNAELTYAITGGNEDGIFKINSE 662 Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 +G + L ++ + +KATD P R T+TI V +I D P+F Sbjct: 663 NGLVSLARPLASSAKIKHKLSLKATDNGVP---RRIGTSTIIVFVI-LADLLPKFPVSPL 718 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215 V+V E V+ + T + ++ + Y I+ GN + F +DSLSGD+ +K L Sbjct: 719 IVNVKEG-------VLPGGRVTTVKMTSSRLMTYRILEGNDEGYFRMDSLSGDLLALKEL 771 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE---SVSENVPI 272 DYE VR++ + I+ QD + ++ L++N+ DVND +P F + E V E + Sbjct: 772 DYEDVRTFTMRIKGQD--TDGNADVVTLVVNLEDVNDCSPVFAGEVGGEVMLRVEEPFLV 829 Query: 273 -GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 G +V++ YD D G LT+ ++D+ + TID + T D Sbjct: 830 AGVPVVKLDVYDKDAG--DRLTFELSDEG-----ERIFTIDDEGQLIPTRSVNDITEPLS 882 Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 + VT D PP ++ +P E + ED G V + Sbjct: 883 F--TVTVRDSASPPHVTSSRVTLNFEKLGEA----LP--VESRVREDAYIGMIVTFVPKV 934 Query: 392 DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD 451 ++ Y FSI + G I VA+PLDF+++ Y LTV +S G S Sbjct: 935 FPKSVFKITYP-----KDPAFSI---DEIGDIRVAKPLDFEKQVSYTLTVREAESIGSSP 986 Query: 452 TA---MVQINITDANNYAPVFEN-APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 +V I++ D N+ P F + +++ G+ VL ++A D D N ++ + Sbjct: 987 RVFDRVVVISVIDVNDNVPRFTGITRIYKRINKNSLNGSPVLSLNALDLDYERNGEVGFQ 1046 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 + D F INP I T L++E+ Y V A D G+P L+ TT Sbjct: 1047 ---------IVPRDGPFGINPVDEMIETTGNLNKES---YEFDVYAFDYGIPRLNSTTIP 1094 Query: 568 EISVVDVNDNEPVFK-----QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 VV V + P+F+ +Y E + G + V A L I YE+ Sbjct: 1095 --MVVHVAEVPPIFEVLDNDHNMYRFETAETSHGGELIGTVKAVSYSKAL---IAYEI-T 1148 Query: 623 KDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 SF I +G IR N ++ E ++L A + + + V I +++IN Sbjct: 1149 SGNVRNSFKIGTLTGEIRHNNFMNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLKNIN 1208 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV-----VHYSIKGGDDSNSFS 736 D+ P F T ++E+ P+GT+I ++ A D D + + + YSI D+++ F+ Sbjct: 1209 DNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTYSI---DNTDMFA 1265 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELV---IRAASPPLWNDVRVEILVTDVNDNAPV 793 + D + V LDYE +V + SP + I + VNDN+PV Sbjct: 1266 I----SPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSY-ANITLLPVNDNSPV 1320 Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853 F + V A D D D + Y I G++ I ++ ++G +TLS Sbjct: 1321 FAQSNYAFQISETAEVGNELAFVTATDRD-GDPITYTI-EGDSGPYI-IDPSSGIITLSR 1377 Query: 854 QLNTNVPKLATMEVSVTDGV 873 + NV + +V TDG+ Sbjct: 1378 EAPVNVWEY-NFKVKATDGI 1396 Score = 138 bits (333), Expect = 8e-32 Identities = 137/488 (28%), Positives = 224/488 (45%), Gaps = 50/488 (10%) Query: 209 VSLVKTL-DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++++K+L ++ V + +++ + P+ T ++ ++I+DVN++AP + + +VS Sbjct: 57 LTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVS 116 Query: 268 ENVPIGYSIVRVQAYDAD--EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 + P IV V A D D EG L ++D D +G ID +G + ++ L Sbjct: 117 SDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSDADSSG--QNRFQIDSSTGTITSTNLLA 174 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 + Y+L V ATD G PP + + F Y + E G V Sbjct: 175 ANNE--YKLTVKATDTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQESLVIGNSV 232 Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 + +TAT + Y I GGN F I G+ I V +PLD++ + YVL V AT Sbjct: 233 LQVTATG---PAAITYSIVGGNKNDAFRIDRTTGQ--IAVNKPLDYEVLQSYVLNVRATC 287 Query: 446 SGGRSDTA---MVQINITDANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A V I +TD N+ +PVF + P T +V P T V Sbjct: 288 ETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKA--------- 338 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 + TY + I +A+A ++ + + T + DR + Y + + A DGG Sbjct: 339 -RRFTYYV---IYEKALA-------VDADSESFGTVRYSDR---AEYTVALVATDGG--G 382 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 S TT + I V ++N+ P F Q Y ++ E+ VGT + + AT AD N + Y + Sbjct: 383 KSTTTSLVIKVFNINE-PPKFPQPKYEFSVPENKQVGTEIGAITATYADP--NTLLKYSI 439 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 + + +F ++ + GVI KALD E+ A+ L A+ + GT + T +V I + DI Sbjct: 440 -TRGNIDDTFCVN-SKGVISLAKALDSETKASFTLDAM-VSHGT--SNHTTVVQITVNDI 494 Query: 681 NDSPPVFE 688 ND+ P+ E Sbjct: 495 NDNWPIME 502 Score = 137 bits (332), Expect = 1e-31 Identities = 180/719 (25%), Positives = 299/719 (41%), Gaps = 71/719 (9%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D FRID +G + LD E + Y + V+AT + ++++ + + + D NDN Sbjct: 254 DAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRAT--CETYTPKIAAEVAVAITLTDVNDNS 311 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F + +V + + V+ K + Y +I + ++D+ Sbjct: 312 PVFLLYSNPTTVTVNSYTPEQTVVFKAR----------RFTYYVI---YEKALAVDA--- 355 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 D T+ Y Y + + A DGG +S TT L+I + ++N+ P+F ++ SV Sbjct: 356 DSESFGTVRYSDRAEYTVALVATDGG--GKSTTTSLVIKVFNINE-PPKFPQPKYEFSVP 412 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN +G I + A AD N L Y++T GN+D ++ + G + + LD E Sbjct: 413 ENKQVGTEIGAITATYADP--NTLLKYSIT----RGNIDDTFCVNSK-GVISLAKALDSE 465 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 T+A + L + G S T M Y VE+ ED+ GT V+ Sbjct: 466 TKASFTLDAMVSHG----TSNHTTVVQITVNDINDNWPIMEPVYNVEVREDQ--GTIVMA 519 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-S 446 HY T N ++T + ++ V ATD Sbjct: 520 SFVIFCIAAVHKHYRRIARKTCHVKVARLDNPLPVLTNKAISSYLAPGTELVKVVATDLD 579 Query: 447 GGRSDTAMVQINITDANNYAPVFE-NAP------YTASVFEDAPIGTTVLVVSATDSDVG 499 GG T I T + +F NA Y ASV + P+ V V ATD+D G Sbjct: 580 GGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLYLASVPYEFPVNFHVFQVIATDADSG 639 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA++TY+++ NE D F IN + G ++ + L + L++ A D GVP Sbjct: 640 SNAELTYAITG--GNE-----DGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVP 692 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 T+ + + V+ + D P F N+ E L G V+ V T + + + RI Sbjct: 693 RRIGTSTIIVFVI-LADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSSRL-MTYRI--- 747 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 L+ D EG F +D SG + K LD E V T ++ D T + V + + +ED Sbjct: 748 LEGND--EGYFRMDSLSGDLLALKELDYEDVRTFTMRIKGQD--TDGNADVVTLVVNLED 803 Query: 680 INDSPPVFESDC---LTFYISENSPI-GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 +ND PVF + + + E + G + ++ +D D G S +G F Sbjct: 804 VNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFELSDEG---ERIF 860 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPV 793 +++ D+ +L+ ++ + + + +R +ASPP RV + + + PV Sbjct: 861 TID-----DEGQLIPTRSVNDITEPLSFTVTVRDSASPPHVTSSRVTLNFEKLGEALPV 914 Score = 126 bits (303), Expect = 3e-28 Identities = 175/693 (25%), Positives = 280/693 (40%), Gaps = 74/693 (10%) Query: 52 IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111 + +N +V I +TA +P + + D F ++ + L +A LD E A Sbjct: 411 VPENKQVGTEIGAITATYADP-NTLLKYSITRGNIDDTFCVNSKGVISLAKA-LDSETKA 468 Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS--VTDNP 169 +T+ + S + T + + + D NDN+P E Y V V ED V + Sbjct: 469 SFTLDAMVSHGTS------NHTTVVQITVNDINDNWP-IMEPVYNVEVREDQGTIVMASF 521 Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLV- 226 VI I A Y I T + L + ++ K + LV Sbjct: 522 VIFCIAAVHK--------HYRRIARKT-CHVKVARLDNPLPVLTNKAISSYLAPGTELVK 572 Query: 227 IRAQDGGSPSRSNTTQLLINIRDVND------NAPRFYTSLFQESVSENVPIGYSIVRVQ 280 + A D T +I +D+ NA +L+ SV P+ + + +V Sbjct: 573 VVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLYLASVPYEFPVNFHVFQVI 632 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 A DAD G NAELTY +T GN D I+ +G V + L + K++L + ATD Sbjct: 633 ATDADSGSNAELTYAITG----GNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATD 688 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400 G P R T+T F V + E PG V T+ T + + Sbjct: 689 NGVPRRIGTST-IIVFVILADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSS---RLMT 744 Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 Y I GN G F + S +G + + LD++ R + + + D+ G +D + +N+ Sbjct: 745 YRILEGNDEGYFRMDSLSGD--LLALKELDYEDVRTFTMRIKGQDTDGNADVVTLVVNLE 802 Query: 461 DANNYAPVFENAPYTASVFE-DAPI---GTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 D N+ +PVF + + P G V+ + D D G ++T+ LS E Sbjct: 803 DVNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAG--DRLTFELSDE----- 855 Query: 517 VAHHDQQFVINPQTGAITTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 ++ F I+ + I T + D E +S TVT RD P ++ V ++ + Sbjct: 856 ---GERIFTIDDEGQLIPTRSVNDITEPLS---FTVTVRDSASPPHVTSSRVTLNFEKLG 909 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 + PV + + EDA +G V+ V +I Y DP +F ID Sbjct: 910 EALPV------ESRVREDAYIGMIVTFVPKVFPKSVF--KITYPKDP------AFSIDEI 955 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 G IR K LD E ++ L + G+ P+ +V I + D+ND+ P F + Sbjct: 956 -GDIRVAKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVPRFTGITRIY 1014 Query: 695 -YISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 I++NS G+ + + A D D N V + I Sbjct: 1015 KRINKNSLNGSPVLSLNALDLDYERNGEVGFQI 1047 Score = 121 bits (291), Expect = 1e-26 Identities = 115/442 (26%), Positives = 195/442 (44%), Gaps = 49/442 (11%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 + I +L ND+SPVF Y + E A G + + ATD+D + YTIE Sbjct: 1306 YANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVTATDRD---GDPITYTIE---G 1359 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D+ P + ID SG ++T + V Y VKATD Sbjct: 1360 DS-GP-----------------YIIDPSSG-IITLSREAPVNVWEYNFKVKATDGI---- 1396 Query: 128 DRLSSTATIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 ++T + ++IID N++ PQF+ E + TV + ++ V+ +++ATD D G N Sbjct: 1397 --FTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAE-NLPSGQVLMQVQATDEDRGLN 1453 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-----N 239 + Y ++ G T FSID+ +G + LD E+ +V+RA+DGG N Sbjct: 1454 GEVEYELVIGFT--DFSIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNIN 1511 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 +++++ D NDN P F+ + SV + P+G+S+VRV+A D D G NA++ YT + Sbjct: 1512 YCLIIVSVVDANDNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTFVEP 1571 Query: 300 DYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 ++ + ++ +G + + Q+ + +T + G D T Sbjct: 1572 SDKFAIEKTTGIVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDDRDRQTLV---VIDV 1628 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQ 417 F Y + + E+ GT + + A ++NR + Y+ N + I + Sbjct: 1629 TTVEPPMFERHLYNISVRENAAVGTTIGQIRA--VSQNNRPIMYQPLHENPNAKEEIGIE 1686 Query: 418 NGRGLITVAQPLDFKQERRYVL 439 G I + LD++ Y L Sbjct: 1687 IDTGSIVTSSKLDYESVNNYEL 1708 Score = 118 bits (285), Expect = 5e-26 Identities = 124/446 (27%), Positives = 197/446 (44%), Gaps = 46/446 (10%) Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSS 510 TA V ++I D NN+AP A Y A+V D P T ++ V+A+D D N Q+ + S Sbjct: 89 TAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVS 148 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 + + +F I+ TG IT+ LL + Y LTV A D G P + V +S Sbjct: 149 DADSSG----QNRFQIDSSTGTITSTNLL--AANNEYKLTVKATDTGSPPMESQVSVTVS 202 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V+ F + Y I E ++G SV QV AT I Y + ++ + +F Sbjct: 203 VITPITTPVKFAEANYAKTIQESLVIGNSVLQVTATGP-----AAITYSIVGGNKND-AF 256 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVF-- 687 ID +G I NK LD E + ++ L A + TP ++ V V I + D+ND+ PVF Sbjct: 257 RIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLL 316 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 S+ T ++ +P T + + R V Y D++S S T + SD+AE Sbjct: 317 YSNPTTVTVNSYTPEQTVVFKARRF------TYYVIYEKALAVDADSESFGTVRYSDRAE 370 Query: 748 -LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 V +V D LVI+ + PP + + E V +N V + Sbjct: 371 YTVALVATDGGGKSTTTSLVIKVFNINEPPKFPQPKYEF---SVPENKQVGTE------- 420 Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863 G + A AD L+Y I GN + +N + G ++L+ L++ Sbjct: 421 ---------IGAITATYADPNTLLKYSITRGNIDDTFCVN-SKGVISLAKALDSETKASF 470 Query: 864 TMEVSVTDGVNEIKAMMQLSVRLITE 889 T++ V+ G + ++Q++V I + Sbjct: 471 TLDAMVSHGTSNHTTVVQITVNDIND 496 Score = 93.1 bits (221), Expect = 3e-18 Identities = 85/320 (26%), Positives = 144/320 (45%), Gaps = 25/320 (7%) Query: 485 GTTVLVVSA----TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 GTT+L S+ D D Q SL E+++ V H + + + L + Sbjct: 8 GTTILDGSSGFQFVDDDTNPE-QFECSLM-EVTSMFVLEHFRVERSDSECRLTVIKSLFE 65 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 +++ + V + P++ T V++S+ DVN++ P Q Y A + D T + Sbjct: 66 HHSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPI 125 Query: 601 SQVGATDADVGL-NGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V A+D D N ++ ++ D + F ID ++G I + L + + L Sbjct: 126 VTVTASDLDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTGTITSTNLLAANN--EYKLTV 183 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D G+PP S V V + + +P F I E+ IG ++ ++ A P Sbjct: 184 KATDTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQESLVIGNSVLQVTATGP--- 240 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA----SPP 773 A + YSI GG+ +++F ++ G ++ LDYE + Y L +RA +P Sbjct: 241 --AAITYSIVGGNKNDAFRIDRTTG----QIAVNKPLDYE-VLQSYVLNVRATCETYTPK 293 Query: 774 LWNDVRVEILVTDVNDNAPV 793 + +V V I +TDVNDN+PV Sbjct: 294 IAAEVAVAITLTDVNDNSPV 313 Score = 47.2 bits (107), Expect = 2e-04 Identities = 59/260 (22%), Positives = 107/260 (41%), Gaps = 28/260 (10%) Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD--EGPNAVV 722 P +T V + I+D+N+ P +S ++P T I + A D D EG V+ Sbjct: 84 PNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVL 143 Query: 723 HYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777 + D S N F +++ G T+ + + +Y+L ++A SPP+ + Sbjct: 144 FQFVSDADSSGQNRFQIDSSTG-------TITSTNLLAANNEYKLTVKATDTGSPPMESQ 196 Query: 778 VRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836 V V + ++T + PV ++ +G V A + Y I+ GN Sbjct: 197 VSVTVSVITPIT--TPVKFAEANYAKTIQESLVIG--NSVLQVTATGPAAITYSIVGGNK 252 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM----- 891 + ++ TTG + ++ L+ V + + V T K +++V + ++ Sbjct: 253 NDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSP 312 Query: 892 --LL--NSITVRLNDMTAEQ 907 LL N TV +N T EQ Sbjct: 313 VFLLYSNPTTVTVNSYTPEQ 332 Score = 38.3 bits (85), Expect = 0.088 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%) Query: 1271 PSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNG--TLAGCPEKRSRCSSAPCYNGAEC 1328 P+S + K+ DF GC+SD + +D + V + GCP C C+N C Sbjct: 3202 PNSTKAKS-DFEGCVSDHRYNGYHMDKDRTVDRYQWRVIKGCP-----CEPGGCFNNGTC 3255 Query: 1329 SDLWDTYICDCKEGHTGKDC 1348 C C+ G+TG C Sbjct: 3256 MANATIPTCKCQPGYTGLTC 3275 >SB_1988| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3889 Score = 288 bits (706), Expect = 5e-77 Identities = 238/796 (29%), Positives = 374/796 (46%), Gaps = 62/796 (7%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 N ND S V Y V + + + LT+ ATD+ I +N V + V+A ++ Sbjct: 1423 NKFTVNDTSGVL----YTTHVLDRETKASYQLTITATDKGIVENMTVGSHVIKVSA--VD 1476 Query: 72 PEDAXXXXXXXXXXVQ-DVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDR 129 P++ D+F I+ SG + A +DRE A Y++LV A D P + Sbjct: 1477 PDEGSNGDILYSLQTDYDIFAINQTSGVIRVVALVDREAHPAGYSLLVVARDHGYPTPN- 1535 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++TA +++ I D NDN P+F + TY+ SV ED +V + +++ATD D G I + Sbjct: 1536 -AATARVNITISDINDNAPRFLKFTYSGSVREDSTVGTE--VVQVQATDDDDGLAGEIVF 1592 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 AI GG+ + FSI + SG +++ ++LD E +Y L + A D +S + ++ I I D Sbjct: 1593 AITGGDPEGLFSILNTSGKITVARSLDREMKATYELTVTATDRAGDPKSTSVEVDITITD 1652 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F +SE+ G ++ V A D D GVN ++ Y G Sbjct: 1653 ANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGDSPK--GK----F 1706 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFMP 368 ++ +G V T G+LD E +Y + + A D G+P S T F Sbjct: 1707 AVNAITGVVSTVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLVDANDNNPTFTK 1766 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y ++E+ GT V+ + AT+ D +D+++ Y I+ G+ F+I +TV Sbjct: 1767 AAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDHFAINH------LTVT 1820 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 +D +R V DTA+ +T + E+ P S +++ G Sbjct: 1821 IHVDDVNDRAPVFRFHNYQKEIPEDTAVGTSILT----VEAIDEDTP---SNTKNSLGGQ 1873 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMS 545 VL V+ATD D+G NAQ+TYS++ + D +F I P +G I T+ L LDRE Sbjct: 1874 LVLKVTATDRDLGTNAQLTYSMAGD---------DNRFTIGPSSGEIRTSSLRLDREAKP 1924 Query: 546 GYLLTVTARDGGVPSLSDTTD-----VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 Y+L VTA D G +D+ D V+ S+VD N + VF T I + Sbjct: 1925 VYVLHVTATDSGGRRATDSDDGANGDVDYSIVDGNVGD-VFTINNATGEIRSFKPLDREA 1983 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +G + G+ Y L + + G F +DP +G+I+T + L+R+ +++L A Sbjct: 1984 --IGVVEDS---EGKGVYRLTIRGSDHGDFTLDPNTGMIKTARNLERQQTFSYNLTIGAA 2038 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G P S+T V I + D+ND+ PVF + + ENSP+GT++ ++ A D D G NA Sbjct: 2039 DHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNA 2098 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777 V YS+ GD F T+ E+ +D + Y L I A P Sbjct: 2099 YVTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVND---FYNLTITATDGGVPISRTA 2155 Query: 778 VRVEIL-VTDVNDNAP 792 + + ++ + D NDN P Sbjct: 2156 IAIALVRILDRNDNEP 2171 Score = 283 bits (695), Expect = 1e-75 Identities = 179/509 (35%), Positives = 267/509 (52%), Gaps = 35/509 (6%) Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 ++A+D GSPS + T + I++ D NDN P+F + ++ S EN GY ++RV A DADE Sbjct: 2952 MKAKDKGSPSLESNTTIEISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIRVSATDADE 3011 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDP 344 G NA+L Y + + SG V SG+LD E+ Q Y L ++ TD G Sbjct: 3012 GTNAQLAYNI--------------VSGTSGIVRPSGRLDYESMVQKHYVLNLSVTDHGVT 3057 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402 ++ A F +Y + E+ P GT V +TA D D ++++ Y Sbjct: 3058 QFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYS 3117 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINIT 460 +TGG+ G FSI G+ I + + ++ + + Y +T++A+D G S A V +++ Sbjct: 3118 LTGGD--GVFSIEPSTGQ--IRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVL 3173 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 D N+ PVF + Y ++ E +GT V A D+D+G N ++ Y E A + Sbjct: 3174 DVNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMY--------EITAGN 3225 Query: 521 DQ-QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 DQ F ++P G+I ++ LDRET LTV A+D G+P LSD V I + DVNDN P Sbjct: 3226 DQGLFTLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDNAP 3285 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 V + + +A + E+A G V QV ATDADV NG + Y + G F I+ +GVI Sbjct: 3286 VIRPRNMSAAVPENAAAGEFVVQVNATDADVERNGHVTYTI--MHGALGMFTINETTGVI 3343 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 RT L+RES + L +A D G P + + + D ND+ P+F + F + EN Sbjct: 3344 RTQGVLNRESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPIFLTTFGPFSVVEN 3403 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 P+GTT+GE+ A D D G NA + Y+I G Sbjct: 3404 MPVGTTVGEVSASDNDIGTNAAISYTISG 3432 Score = 276 bits (677), Expect = 2e-73 Identities = 241/876 (27%), Positives = 383/876 (43%), Gaps = 59/876 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND +PVF Y+ + E + GT++LT++A D+D N + +LV T Sbjct: 1821 IHVDDVNDRAPVFRFHNYQKEIPEDTAVGTSILTVEAIDEDTPSNTKNSLGGQLVLKVTA 1880 Query: 71 NPEDAXXXXXXXXXXVQD--VFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQAS--P 125 D D F I SG + T + LDRE Y + V ATD Sbjct: 1881 TDRDLGTNAQLTYSMAGDDNRFTIGPSSGEIRTSSLRLDREAKPVYVLHVTATDSGGRRA 1940 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + + +I+D N F+ T + D I ++ ++ Sbjct: 1941 TDSDDGANGDVDYSIVDGNVG-DVFTINNATGEI-RSFKPLDREAIGVVEDSE-----GK 1993 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + I G+ F++D +G + + L+ +Q SY L I A D G PS S TT++ I Sbjct: 1994 GVYRLTIRGSDHGDFTLDPNTGMIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSI 2053 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D+NDN P F + + +V EN P+G S++ V A DAD G NA +TY++T D G + Sbjct: 2054 VVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHG-L 2112 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXX 364 +T G + +G LDRE Y L +TATDGG P R+A A Sbjct: 2113 FRAVT-KSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNEP 2171 Query: 365 XFMPGQYEVELAEDEPPGTPV-VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F +Y + E+ PG PV + + +R H N G FS T R Sbjct: 2172 KFSHARYTGSIQENSGPGVPVQMRQHSVFYQPSHRRH------NNPG-FSNTEPRSRAHN 2224 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + P R+ + T G A V I++ DAN+ P F + +++ E A Sbjct: 2225 KLTLP-------RHAADQAGT---GHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAAS 2274 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 IG +V V+A D D G+N +I +S++S + +F I G + + LDRE Sbjct: 2275 IGQSVARVTANDPDSGLNGRIFFSINS--------GSEGKFEIGRSDGVVRVSGSLDREA 2326 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y+L V+A DG V +++ DVNDN P F + + ++ E VG+ + Sbjct: 2327 KAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNA 2386 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 ATD D G N I Y + F I+ +G + + LDRE+ + A DGG Sbjct: 2387 TATDPDQGSNAAITYSM-----SYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDGG 2441 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 S V V+++I D ND+ P F + + + +P+GT + + A D D G N V Sbjct: 2442 --GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVT 2499 Query: 724 YSIKGGDDSNSFSLETRQGSDKA-ELVTMVDL---DYESPRKKYELVIRA---ASPPLWN 776 Y+I+ D F+++ G ++++ + L + S + + A + P Sbjct: 2500 YAIRDSRDPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRAT 2559 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGN 835 +V V I + D D++PV + +D P+G V + Y I G+ Sbjct: 2560 NVTVVINIVDSGDDSPVFNTSSYVVKIDED-RPIGSSVVMVEVVKKRAGTIIMYSI--GS 2616 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + N+ ++ TG +T + +L+ + V TD Sbjct: 2617 SQNVFSIDNLTGLVTTAAKLDRESRDDYVITVQATD 2652 Score = 262 bits (642), Expect = 3e-69 Identities = 175/513 (34%), Positives = 260/513 (50%), Gaps = 37/513 (7%) Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 +KA D+ SP L S TI +++ID NDN P+FS Y S E+ + ++ A Sbjct: 2952 MKAKDKGSP---SLESNTTIEISLIDTNDNVPKFSSPVYYASAPEN--AYGGYQVIRVSA 3006 Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGS 234 TDAD G N+ + Y I+ G SG V LDYE + + Y L + D G Sbjct: 3007 TDADEGTNAQLAYNIVSGT----------SGIVRPSGRLDYESMVQKHYVLNLSVTDHGV 3056 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 ++ L I++ D NDN P+F S + +V EN+P+G + V A D D G+N+++ Y Sbjct: 3057 TQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMY 3116 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++T D +I+P +G + ++RE + Y + +TA+D G P S+ A Sbjct: 3117 SLTGGDGV------FSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHV 3170 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF 412 F YE ++E GT ++ A DAD + R+ YEIT GN +G F Sbjct: 3171 HVLDVNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEITAGNDQGLF 3230 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470 ++ G I V++PLD + + LTV A D G SD A V I +TD N+ APV Sbjct: 3231 TLDPV--LGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDNAPVIR 3288 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 +A+V E+A G V+ V+ATD+DV N +TY+ I + A+ F IN T Sbjct: 3289 PRNMSAAVPENAAAGEFVVQVNATDADVERNGHVTYT----IMHGALG----MFTINETT 3340 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G I T +L+RE+ Y L V ARD G D +++ V+D NDN P+F ++ Sbjct: 3341 GVIRTQGVLNRESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPIFLTTFGPFSV 3400 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 +E+ VGT+V +V A+D D+G N I Y + K Sbjct: 3401 VENMPVGTTVGEVSASDNDIGTNAAISYTISGK 3433 Score = 258 bits (631), Expect = 6e-68 Identities = 221/713 (30%), Positives = 333/713 (46%), Gaps = 69/713 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND++P F Y SVRE ++ GT V+ ++ATD D G E+ + I T Sbjct: 1543 ITISDINDNAPRFLKFTYSGSVREDSTVGTEVVQVQATDDDDGLAGEIVFAI---TGG-- 1597 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +PE +F I SG + SLDRE A Y + V ATD+A D Sbjct: 1598 DPE--------------GLFSILNTSGKITVARSLDREMKATYELTVTATDRA---GDPK 1640 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S++ + + I D NDN P F+ T+ + E ++ PVI + ATD D+G N +RY Sbjct: 1641 STSVEVDITITDANDNKPVFTNIPATILLSES-TIPGTPVIT-VVATDQDIGVNGQVRY- 1697 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIRD 249 +G + + +F++++++G VS V LDYE V+ Y + I A D G P ++TT L I++ D Sbjct: 1698 -VGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLVD 1756 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F + + VSE G +++ V A + D G ++++TY ++ D + Sbjct: 1757 ANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDH----F 1812 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ + ++ DR ++ ++ T + G Sbjct: 1813 AINHLTVTIHVDDVNDRAPVFRFHNYQKEIPEDTAVGTSILTVEAIDEDTPSNTKNSLGG 1872 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Q +++ T T D + +L Y + G + RF+I +G + T + L Sbjct: 1873 QLVLKV-----------TATDRDLGTNAQLTYSMAGDD--NRFTIGPSSGE-IRTSSLRL 1918 Query: 430 DFKQERRYVLTVSATDSGGRSDT-------AMVQINITDANNYAPVFENAPYTASVFEDA 482 D + + YVL V+ATDSGGR T V +I D N VF T + Sbjct: 1919 DREAKPVYVLHVTATDSGGRRATDSDDGANGDVDYSIVD-GNVGDVFTINNATGEIRSFK 1977 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+ + V G+ Y L+ S+ H D F ++P TG I T + L+R+ Sbjct: 1978 PLDREAIGVVEDSEGKGV-----YRLTIRGSD----HGD--FTLDPNTGMIKTARNLERQ 2026 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y LT+ A D G+PS S TT V I V D+NDN PVF Y+ + E++ VGTS+ Sbjct: 2027 QTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLD 2086 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSF--VIDPASGVIRTNKALDRESVATHDLKAVAI 660 V ATDAD G N + Y + D G F V G I LDRE ++L A Sbjct: 2087 VTATDADSGQNAYVTYSVTAGD-SHGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITAT 2145 Query: 661 DGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 DGG P +++ I ++I D ND+ P F T I ENS G + ++R H Sbjct: 2146 DGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPV-QMRQH 2197 Score = 254 bits (622), Expect = 8e-67 Identities = 251/877 (28%), Positives = 386/877 (44%), Gaps = 91/877 (10%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + I + D ND+ PVF + E GT V+T+ ATDQDIG N +V Y + Sbjct: 1644 VEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGD--- 1700 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 +P+ F ++ +G + T LD E V RYTV + A DQ P Sbjct: 1701 ----SPKGK--------------FAVNAITGVVSTVGELDYEDVQRYTVYIVAIDQGEP- 1741 Query: 127 SDRLSSTATIHVNI--IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 +L+ST T+H+NI +D NDN P F++ YT V E+ + N ++ + AT+ D G + Sbjct: 1742 --QLNST-TLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIM--VNATERDSGKD 1796 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 S I Y I G+ F+I+ L+ + + D V + + P + + Sbjct: 1797 SKITYNISAGDPLDHFAINHLTVTIHVDDVNDRAPVFRFHNYQKE----IPEDTAVGTSI 1852 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + ++++ P S ++N G +++V A D D G NA+LTY+M D Sbjct: 1853 LTVEAIDEDTP---------SNTKNSLGGQLVLKVTATDRDLGTNAQLTYSMAGDDNR-- 1901 Query: 305 VDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 TI P SG + TS +LDRE + Y L VTATD G R AT + Sbjct: 1902 ----FTIGPSSGEIRTSSLRLDREAKPVYVLHVTATDSGG--RRATDSDDGANGDVDYSI 1955 Query: 364 XXFMPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLH--YEIT-GGNTRGRFSITSQNG 419 G + + A E + A ED+ Y +T G+ G F++ G Sbjct: 1956 VDGNVGDVFTINNATGEIRSFKPLDREAIGVVEDSEGKGVYRLTIRGSDHGDFTLDPNTG 2015 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 +I A+ L+ +Q Y LT+ A D G S T V I + D N+ PVF Y+ + Sbjct: 2016 --MIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTT 2073 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 VFE++P+GT++L V+ATD+D G NA +TYS+++ S H + V G I Sbjct: 2074 VFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDS-----HGLFRAVTKSNHGTIEVAG 2128 Query: 538 LLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LDRE Y LT+TA DGGVP S + + ++D NDNEP F YT +I E++ Sbjct: 2129 NLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGP 2188 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G V + Y+ + F S ++A ++ ++ H Sbjct: 2189 GVPVQM---------RQHSVFYQPSHRRHNNPGF-----SNTEPRSRAHNKLTLPRH--- 2231 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A GT +S +V I + D ND+ P F + ISE + IG ++ + A+DPD Sbjct: 2232 -AADQAGTGHESLAEVV-IHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDS 2289 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 G N + +SI G + E + + +D + ++ I + P Sbjct: 2290 GLNGRIFFSINSGSEG---KFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREG 2346 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835 V + + DVNDN P K + FN + + VG V A D I Sbjct: 2347 YGTVTVTLQDVNDNTP--KFTKPAFNVDVSEGVAVGSV-IVNATATDPDQGSNAAITYSM 2403 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + +N TGS+T++ L+ + + V DG Sbjct: 2404 SYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDG 2440 Score = 240 bits (588), Expect = 1e-62 Identities = 161/508 (31%), Positives = 237/508 (46%), Gaps = 31/508 (6%) Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 A D + +++I++ D NDN PRF S Q ++SE IG S+ RV A D D G+ Sbjct: 2232 AADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGL 2291 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 N + +++ G + I G V SG LDRE +A Y L V+A DG PR Sbjct: 2292 NGRIFFSINSGS-EGKFE----IGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREG 2346 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 T F + V+++E G+ +V TATD D+ + IT + Sbjct: 2347 YGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNA--AITYSMS 2404 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 F+I S G +T+ +PLD + ++ Y TV A D GG V + I D N+ +P Sbjct: 2405 YPGFAINSNTGS--VTITRPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQ 2462 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F Y V + P+GT VL V+A D DVG N +TY++ + F I+ Sbjct: 2463 FPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRD-------SRDPGLFTIDA 2515 Query: 529 QTGAITTNKLLDRETM--SGYL-------LTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 G IT NK++ R + SG+L V ARD G + V I++VD D+ P Sbjct: 2516 NNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGDDSP 2575 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 VF Y I ED +G+SV V G I Y + + F ID +G++ Sbjct: 2576 VFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAGT--IIMYSI---GSSQNVFSIDNLTGLV 2630 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISE 698 T LDRES + + A D G P+ V I + DIND+ P F+ ++E Sbjct: 2631 TTAAKLDRESRDDYVITVQATDNGQTPRVGYTSVVIHVTDINDNAPKFQFPAPYKMTVNE 2690 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 ++ +GT +G ++A D D+G N + Y+I Sbjct: 2691 DAALGTGVGRVKAIDGDQGLNGMFEYAI 2718 Score = 233 bits (571), Expect = 1e-60 Identities = 223/768 (29%), Positives = 357/768 (46%), Gaps = 68/768 (8%) Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 V+D T HV + +Y Q + + E+++V + + K+ A D D G+N Sbjct: 1427 VNDTSGVLYTTHVLDRETKASY-QLTITATDKGIVENMTVGSH--VIKVSAVDPDEGSNG 1483 Query: 186 AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPS-RSNTTQ 242 I Y++ T F+I+ SG + +V +D E Y L++ A+D G P+ + T + Sbjct: 1484 DILYSL---QTDYDIFAINQTSGVIRVVALVDREAHPAGYSLLVVARDHGYPTPNAATAR 1540 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + I I D+NDNAPRF + SV E+ +G +V+VQA D D+G+ E+ + +T D Sbjct: 1541 VNITISDINDNAPRFLKFTYSGSVREDSTVGTEVVQVQATDDDDGLAGEIVFAITGGDPE 1600 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 G + T SG + + LDRE +A Y+L VTATD P+S + Sbjct: 1601 GLFSILNT----SGKITVARSLDREMKATYELTVTATDRAGDPKSTSVEVDITITDANDN 1656 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F + L+E PGTPV+T+ ATD D G + +G+F++ + G + Sbjct: 1657 KPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGDSPKGKFAVNAITG--V 1714 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVF 479 ++ LD++ +RY + + A D G S T + I++ DAN+ P F A YTA V Sbjct: 1715 VSTVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAHVS 1774 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+A GT V++V+AT+ D G +++ITY++S+ + + H F IN T I + + Sbjct: 1775 EEATAGTNVIMVNATERDSGKDSKITYNISA---GDPLDH----FAINHLTVTIHVDDVN 1827 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DR + + + + T V S++ V E + + T + +++L G Sbjct: 1828 DRAPVFRF-------HNYQKEIPEDTAVGTSILTV---EAIDED---TPSNTKNSLGGQL 1874 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAV 658 V +V ATD D+G N ++ Y + D F I P+SG IRT+ LDRE+ + L Sbjct: 1875 VLKVTATDRDLGTNAQLTYSMAGDDNR---FTIGPSSGEIRTSSLRLDREAKPVYVLHVT 1931 Query: 659 AIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT-TIGEIRAH 712 A D G + V I D N VF + T I P+ IG + Sbjct: 1932 ATDSGGRRATDSDDGANGDVDYSIVDGNVGD-VFTINNATGEIRSFKPLDREAIGVV--- 1987 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771 + EG V +I+G D + F+L+ G K T +L+ + Y L I AA Sbjct: 1988 EDSEG-KGVYRLTIRGSDHGD-FTLDPNTGMIK----TARNLERQQTFS-YNLTIGAADH 2040 Query: 772 --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK-- 826 P RV I+V D+NDN PV +++ PVG V A DAD Sbjct: 2041 GLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENS-PVGTSLLDVTATDADSGQNAY 2099 Query: 827 LQYRILSGNNANLI--LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + Y + +G++ L + G++ ++ L+ V + ++ TDG Sbjct: 2100 VTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITATDG 2147 Score = 233 bits (571), Expect = 1e-60 Identities = 172/527 (32%), Positives = 253/527 (48%), Gaps = 40/527 (7%) Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 T A + A D G P + T F Y E+ G V+ Sbjct: 2944 TAASQLAKMKAKDKGSPSLESNTTIEISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIR 3003 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATD 445 ++ATDADE G N + ++I S G++ + LD++ ++ YVL +S TD Sbjct: 3004 VSATDADE---------GTNAQLAYNIVSGTS-GIVRPSGRLDYESMVQKHYVLNLSVTD 3053 Query: 446 SGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G T A++ I++TD N+ P F + Y+A+V E+ P+GT V +V+A D D GIN+Q Sbjct: 3054 HGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQ 3113 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 I YSL+ D F I P TG I K ++RE Y +T+TA D G P LS Sbjct: 3114 IMYSLTGG---------DGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSS 3164 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 V + V+DVNDN PVF ++Y + E VGT V A DAD+G NGR+ YE+ Sbjct: 3165 DAKVHVHVLDVNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEI-TA 3223 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 ++G F +DP G IR ++ LDRE+ T L +A D G P S V I + D+ND+ Sbjct: 3224 GNDQGLFTLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDN 3283 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PV ++ + EN+ G + ++ A D D N V Y+I G F++ G Sbjct: 3284 APVIRPRNMSAAVPENAAAGEFVVQVNATDADVERNGHVTYTIMHG-ALGMFTINETTGV 3342 Query: 744 DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800 + + V L+ ES + Y L++ A + P + +++ V D NDN P+ F Sbjct: 3343 IRTQGV----LNRES-KDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPI---FLTT 3394 Query: 801 FNNYK--DCFPVG-PFGRVPAYDADV-TDKLQYRILSGNNANLILLN 843 F + + PVG G V A D D+ T+ +SG + LN Sbjct: 3395 FGPFSVVENMPVGTTVGEVSASDNDIGTNAAISYTISGKGPMSLRLN 3441 Score = 225 bits (549), Expect = 5e-58 Identities = 168/516 (32%), Positives = 239/516 (46%), Gaps = 43/516 (8%) Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 A DQA + L A + ++++D NDN P+F + ++ E S+ + +A++ A D Sbjct: 2232 AADQAGTGHESL---AEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQS--VARVTAND 2286 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 D G N I ++I G+ + +F I G V + +LD E Y L + A DG R Sbjct: 2287 PDSGLNGRIFFSINSGS-EGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPRE 2345 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + + ++DVNDN P+F F VSE V +G IV A D D+G NA +TY+M+ Sbjct: 2346 GYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMS- 2404 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 Y G I+ +G V + LDRET+ Y V A DGG + Sbjct: 2405 --YPG-----FAINSNTGSVTITRPLDRETKQAYSFTVHARDGGG--LESNVAVNVEIGD 2455 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS 416 F QY+ ++ + P GT V+ + A D D N H Y I G F+I + Sbjct: 2456 ENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRDSRDPGLFTIDA 2515 Query: 417 QNGRGLITVAQPLD---------FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465 N GLITV + + +V V A D G R+ V INI D+ + Sbjct: 2516 NN--GLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGDD 2573 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 +PVF + Y + ED PIG++V++V G I YS+ S F Sbjct: 2574 SPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAG--TIIMYSIGSS---------QNVFS 2622 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQ 584 I+ TG +TT LDRE+ Y++TV A D G T V I V D+NDN P F+ Sbjct: 2623 IDNLTGLVTTAAKLDRESRDDYVITVQATDNGQTPRVGYTSVVIHVTDINDNAPKFQFPA 2682 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 Y + EDA +GT V +V A D D GLNG Y + Sbjct: 2683 PYKMTVNEDAALGTGVGRVKAIDGDQGLNGMFEYAI 2718 Score = 210 bits (514), Expect = 9e-54 Identities = 162/511 (31%), Positives = 240/511 (46%), Gaps = 51/511 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+VLD ND++P F ++++ E AS G +V + A D D G N + ++I Sbjct: 2248 IHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN------- 2300 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I G + SLDRE A Y + V A D + S R Sbjct: 2301 -------------SGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGS--YSPR- 2344 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+ V + D NDN P+F++ + V V E ++V VI ATD D G+N+AI Y+ Sbjct: 2345 EGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAV--GSVIVNATATDPDQGSNAAITYS 2402 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + F+I+S +G V++ + LD E ++Y + A+DGG SN + + I D Sbjct: 2403 M----SYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDGGG-LESNVA-VNVEIGDE 2456 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN+P+F T +Q V + P+G ++ V A D D G N +TY + D G T Sbjct: 2457 NDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRDSRDPGL----FT 2512 Query: 311 IDPRSGWVYTSGQLDR---------ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 ID +G + + + R + V A D G PR+ T Sbjct: 2513 IDANNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGD 2572 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F Y V++ ED P G+ VV + + Y I G+++ FSI N G Sbjct: 2573 DSPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAGTIIMYSI--GSSQNVFSI--DNLTG 2628 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE-NAPYTASV 478 L+T A LD + YV+TV ATD+G R V I++TD N+ AP F+ APY +V Sbjct: 2629 LVTTAAKLDRESRDDYVITVQATDNGQTPRVGYTSVVIHVTDINDNAPKFQFPAPYKMTV 2688 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 EDA +GT V V A D D G+N Y+++ Sbjct: 2689 NEDAALGTGVGRVKAIDGDQGLNGMFEYAIT 2719 Score = 199 bits (486), Expect = 2e-50 Identities = 158/493 (32%), Positives = 225/493 (45%), Gaps = 49/493 (9%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F+P + ++E G V +TA D D + R+ + I G+ G+F I +G ++ Sbjct: 2260 FIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGS-EGKFEIGRSDG--VV 2316 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 V+ LD + + YVL VSA D R V + + D N+ P F + V E Sbjct: 2317 RVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEG 2376 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +G+ ++ +ATD D G NA ITYS+S F IN TG++T + LDR Sbjct: 2377 VAVGSVIVNATATDPDQGSNAAITYSMSYP-----------GFAINSNTGSVTITRPLDR 2425 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ET Y TV ARDGG L V + + D NDN P F Y ++++ VGT V Sbjct: 2426 ETKQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVL 2483 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL------ 655 V A D DVG NG + Y + R+ G F ID +G+I NK + R + Sbjct: 2484 AVNAEDRDVGNNGHVTYAIRDS-RDPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGS 2542 Query: 656 ---KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 K A D GT P+++ V V I I D D PVF + I E+ PIG+++ + Sbjct: 2543 FVFKVEARDHGTSPRATNVTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEVV 2602 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771 G ++ YSI G N FS++ G + T LD ES R Y + ++A Sbjct: 2603 KKRAG--TIIMYSI--GSSQNVFSIDNLTGL----VTTAAKLDRES-RDDYVITVQATDN 2653 Query: 772 --PPLWNDVRVEILVTDVNDNAPVMK---DFQIIFNNYKDCFPVGPFGRVPAYDAD--VT 824 P V I VTD+NDNAP + +++ N +D GRV A D D + Sbjct: 2654 GQTPRVGYTSVVIHVTDINDNAPKFQFPAPYKMTVN--EDAALGTGVGRVKAIDGDQGLN 2711 Query: 825 DKLQYRILSGNNA 837 +Y I N A Sbjct: 2712 GMFEYAITHANIA 2724 Score = 193 bits (470), Expect = 2e-48 Identities = 103/257 (40%), Positives = 152/257 (59%), Gaps = 12/257 (4%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + F ID +G + LDRE YT+ VKATD PV R S+ A ++V ++D ND Sbjct: 1214 ISHTFAIDPMTGDIRAVGLLDRETKLNYTLDVKATD-VDPVDPRWSA-AVVYVEVLDSND 1271 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P F +++Y V + E T + K++ATD DVG+N I Y+I+ GN F IDS Sbjct: 1272 NAPVFKKQSYVVEMVEHSPTTFT--VVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSS 1329 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 SG + + +D E+++ Y L ++AQDGGSP+ T Q+ INI+DVNDN P +S + S Sbjct: 1330 SGVIKPAQDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTAS 1389 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V EN P G S++++ +D D N ++ +T+ + + T++ SG +YT+ LD Sbjct: 1390 VPENQPPGQSVLKISVFDPDHAGNGQVAFTVNNNKF--------TVNDTSGVLYTTHVLD 1441 Query: 326 RETQAKYQLLVTATDGG 342 RET+A YQL +TATD G Sbjct: 1442 RETKASYQLTITATDKG 1458 Score = 185 bits (451), Expect = 4e-46 Identities = 153/506 (30%), Positives = 233/506 (46%), Gaps = 45/506 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+++D ND+ P F Y AS E A G V+ + ATD D G NA++ Y I T+ Sbjct: 2969 EISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIRVSATDADEGTNAQLAYNIVSGTSGI 3028 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + P SG L + + + V +V Q + S Sbjct: 3029 VRP-----------------------SGRLDYESMVQKHYVLNLSVTDHGVTQFT--SFA 3063 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + + N D+ + Q SE + TV E++ V + + D+ + NS I Y Sbjct: 3064 LLNISVTDFN--DNQPQFNQ-SEYSATVL--ENMPVGTKVTMVTARDEDSGI--NSQIMY 3116 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ GG+ FSI+ +G + L K ++ E +Y + I A D G+P S+ ++ +++ D Sbjct: 3117 SLTGGDG--VFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLD 3174 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F + +++ ++SE V +G VQA DAD G N + Y +T GN Sbjct: 3175 VNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEIT----AGNDQGLF 3230 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 T+DP G + S LDRET L V A D G P S A+ P Sbjct: 3231 TLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDNAPVIRPR 3290 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427 + E+ G VV + ATDAD + H Y I G G F+I G+I Sbjct: 3291 NMSAAVPENAAAGEFVVQVNATDADVERNGHVTYTIMHG-ALGMFTINETT--GVIRTQG 3347 Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 L+ + + Y L V A D G D + +++ D N+ P+F SV E+ P+G Sbjct: 3348 VLNRESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPIFLTTFGPFSVVENMPVG 3407 Query: 486 TTVLVVSATDSDVGINAQITYSLSSE 511 TTV VSA+D+D+G NA I+Y++S + Sbjct: 3408 TTVGEVSASDNDIGTNAAISYTISGK 3433 Score = 165 bits (402), Expect = 3e-40 Identities = 89/230 (38%), Positives = 141/230 (61%), Gaps = 9/230 (3%) Query: 436 RYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 +Y+LT++A + S S +V++N+ D N+ P F+++ Y S+ E +P GT+V+ V+ Sbjct: 3631 QYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISEASPPGTSVVKVT 3690 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A D D G N+++ Y I ++A + + F IN +TG ++T +D + + V Sbjct: 3691 AIDKDEGTNSRVLY----RIRHDASSANSDVFSINAETGVLSTQVFIDEYEYRAFTVIVE 3746 Query: 553 ARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 A+D G P+ LS T V +++VDVNDN+PVF +LY+ +I E AL G+SV QV ATDAD G Sbjct: 3747 AKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVAATDADTG 3806 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 +N R+ Y + D E+G F I+ ++G+I N ALDRES+ + L A + Sbjct: 3807 INSRLTYRIISGD-EQGHFAINASTGLISVNSALDRESIDSFRLTVGAFN 3855 Score = 160 bits (389), Expect = 1e-38 Identities = 115/372 (30%), Positives = 187/372 (50%), Gaps = 30/372 (8%) Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T + L + A+D G PSL T +EIS++D NDN P F +Y A+ E+A G V + Sbjct: 2944 TAASQLAKMKAKDKGSPSLESNTTIEISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIR 3003 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATHDLKAVAI- 660 V ATDAD G N ++ Y ++ SG++R + LD ES V H + +++ Sbjct: 3004 VSATDADEGTNAQLAYN-----------IVSGTSGIVRPSGRLDYESMVQKHYVLNLSVT 3052 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G +S +++I + D ND+ P F + + EN P+GT + + A D D G N+ Sbjct: 3053 DHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINS 3112 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777 + YS+ GGD FS+E G + + ++ E+ ++ Y + I A+ +P L +D Sbjct: 3113 QIMYSLTGGD--GVFSIEPSTGQIRLQKA----INREA-KENYHVTITASDRGTPVLSSD 3165 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADV--TDKLQYRILSG 834 +V + V DVNDN PV ++ + VG V A DAD+ ++ Y I +G Sbjct: 3166 AKVHVHVLDVNDNPPVFTS-RVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEITAG 3224 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLL 893 N+ L L+ GS+ +S L+ K T+ V D G+ ++ Q SV + ++ Sbjct: 3225 NDQGLFTLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSD--QASVVIYLTDVND 3282 Query: 894 NSITVRLNDMTA 905 N+ +R +M+A Sbjct: 3283 NAPVIRPRNMSA 3294 Score = 151 bits (367), Expect = 6e-36 Identities = 97/258 (37%), Positives = 137/258 (53%), Gaps = 11/258 (4%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFK 582 F I+P TG I LLDRET Y L V A D V V + V+D NDN PVFK Sbjct: 1218 FAIDPMTGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFK 1277 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 +Q Y ++E + +V +V ATD DVG NGRI Y + +G+FVID +SGVI+ Sbjct: 1278 KQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSI-VSGNVDGAFVIDSSSGVIKPA 1336 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 + +DRE + + L A DGG+P +TV V I I+D+ND+ PV S T + EN P Sbjct: 1337 QDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPENQPP 1396 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 G ++ +I DPD N V +++ ++N F++ G L T LD E+ + Sbjct: 1397 GQSVLKISVFDPDHAGNGQVAFTV----NNNKFTVNDTSG----VLYTTHVLDRET-KAS 1447 Query: 763 YELVIRAASPPLWNDVRV 780 Y+L I A + ++ V Sbjct: 1448 YQLTITATDKGIVENMTV 1465 Score = 147 bits (356), Expect = 1e-34 Identities = 91/250 (36%), Positives = 134/250 (53%), Gaps = 16/250 (6%) Query: 429 LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + + Y L V ATD R A+V + + D+N+ APVF+ Y + E +P Sbjct: 1233 LDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVVEMVEHSPTT 1292 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 TV+ V ATD DVG N +I+YS+ S + D FVI+ +G I + +DRE + Sbjct: 1293 FTVVKVEATDRDVGSNGRISYSIVS-------GNVDGAFVIDSSSGVIKPAQDIDREKIQ 1345 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 YLL V A+DGG P+L T V I++ DVNDN PV YTA++ E+ G SV ++ Sbjct: 1346 RYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPENQPPGQSVLKISV 1405 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D NG++ + ++ F ++ SGV+ T LDRE+ A++ L A D G Sbjct: 1406 FDPDHAGNGQVAFTVN-----NNKFTVNDTSGVLYTTHVLDRETKASYQLTITATDKGI- 1459 Query: 666 PQSSTVIVHI 675 ++ TV H+ Sbjct: 1460 VENMTVGSHV 1469 Score = 140 bits (339), Expect = 1e-32 Identities = 95/254 (37%), Positives = 131/254 (51%), Gaps = 20/254 (7%) Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXFMP 368 IDP +G + G LDRET+ Y L V ATD DP PR + A F Sbjct: 1220 IDPMTGDIRAVGLLDRETKLNYTLDVKATDV-DPVDPRWSAAVVYVEVLDSNDNAPVFKK 1278 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y VE+ E P VV + ATD D + R+ Y I GN G F I S +G +I A Sbjct: 1279 QSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSSSG--VIKPA 1336 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPI 484 Q +D ++ +RY+L V A D G + A VQ INI D N+ PV ++ YTASV E+ P Sbjct: 1337 QDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPENQPP 1396 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G +VL +S D D N Q+ +++ ++ +F +N +G + T +LDRET Sbjct: 1397 GQSVLKISVFDPDHAGNGQVAFTV-----------NNNKFTVNDTSGVLYTTHVLDRETK 1445 Query: 545 SGYLLTVTARDGGV 558 + Y LT+TA D G+ Sbjct: 1446 ASYQLTITATDKGI 1459 Score = 140 bits (338), Expect = 2e-32 Identities = 82/233 (35%), Positives = 128/233 (54%), Gaps = 20/233 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NVLD ND P F+ Y S+ E + GT+V+ + A D+D G N+ V Y I Sbjct: 3654 RVNVLDVNDDIPAFKSSSYNMSISEASPPGTSVVKVTAIDKDEGTNSRVLYRIR------ 3707 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 DA DVF I+ +G L T+ +D + +TV+V+A D SP + Sbjct: 3708 ---HDASSANS-------DVFSINAETGVLSTQVFIDEYEYRAFTVIVEAKDMGSPTA-- 3755 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSST ++V I+D NDN P F+ K Y+ S+ E S + + ++ ATDAD G NS + Y Sbjct: 3756 LSSTVPVYVTIVDVNDNQPVFANKLYSTSISE--SALNGSSVIQVAATDADTGINSRLTY 3813 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 II G+ Q F+I++ +G +S+ LD E + S+RL + A + + + +NT++ Sbjct: 3814 RIISGDEQGHFAINASTGLISVNSALDRESIDSFRLTVGAFNDEALAFNNTSR 3866 Score = 128 bits (309), Expect = 6e-29 Identities = 77/238 (32%), Positives = 132/238 (55%), Gaps = 14/238 (5%) Query: 106 DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165 +RE++++Y + + A + + S LSS + VN++D ND+ P F +Y +S+ E + Sbjct: 3625 NRERISQYLLTITAANLDT--SPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISE--AS 3680 Query: 166 TDNPVIAKIKATDADVGANSAIRYAI----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221 + K+ A D D G NS + Y I N+ + FSI++ +G +S +D + R Sbjct: 3681 PPGTSVVKVTAIDKDEGTNSRVLYRIRHDASSANSDV-FSINAETGVLSTQVFIDEYEYR 3739 Query: 222 SYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 ++ +++ A+D GSP+ S+T + + I DVNDN P F L+ S+SE+ G S+++V Sbjct: 3740 AFTVIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVA 3799 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 A DAD G+N+ LTY + D G+ I+ +G + + LDRE+ ++L V A Sbjct: 3800 ATDADTGINSRLTYRIISGDEQGH----FAINASTGLISVNSALDRESIDSFRLTVGA 3853 Score = 124 bits (299), Expect = 1e-27 Identities = 104/339 (30%), Positives = 162/339 (47%), Gaps = 20/339 (5%) Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQL-YTAN---IMEDALVGTSVSQVGATDADVGLNGR 615 +++DT+ V + V D E QL TA I+E+ VG+ V +V A D D G NG Sbjct: 1426 TVNDTSGV-LYTTHVLDRETKASYQLTITATDKGIVENMTVGSHVIKVSAVDPDEGSNGD 1484 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATHDLKAVAIDGGTP-PQSSTVIV 673 I Y L + F I+ SGVIR +DRE+ A + L VA D G P P ++T V Sbjct: 1485 ILYSLQT---DYDIFAINQTSGVIRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARV 1541 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 +I I DIND+ P F + + E+S +GT + +++A D D+G + ++I GGD Sbjct: 1542 NITISDINDNAPRFLKFTYSGSVREDSTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEG 1601 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790 FS+ G ++ LD E + YEL + A A P V V+I +TD NDN Sbjct: 1602 LFSILNTSG----KITVARSLDREM-KATYELTVTATDRAGDPKSTSVEVDITITDANDN 1656 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850 PV + + P P V A D D+ Q R + + +N TG ++ Sbjct: 1657 KPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGDSPKGKFAVNAITGVVS 1716 Query: 851 LSPQLN-TNVPKLATMEVSVTDGVNEIKA-MMQLSVRLI 887 +L+ +V + V++ G ++ + + L++ L+ Sbjct: 1717 TVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLV 1755 Score = 122 bits (295), Expect = 3e-27 Identities = 75/209 (35%), Positives = 113/209 (54%), Gaps = 4/209 (1%) Query: 538 LLDRETMSGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 L +RE +S YLLT+TA + P+LS V ++V+DVND+ P FK Y +I E + Sbjct: 3623 LQNRERISQYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISEASPP 3682 Query: 597 GTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 GTSV +V A D D G N R+ Y + D F I+ +GV+ T +D Sbjct: 3683 GTSVVKVTAIDKDEGTNSRVLYRIRHDASSANSDVFSINAETGVLSTQVFIDEYEYRAFT 3742 Query: 655 LKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 + A D G+P SSTV V++ I D+ND+ PVF + + ISE++ G+++ ++ A D Sbjct: 3743 VIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVAATD 3802 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 D G N+ + Y I GD+ F++ G Sbjct: 3803 ADTGINSRLTYRIISGDEQGHFAINASTG 3831 Score = 119 bits (287), Expect = 3e-26 Identities = 84/264 (31%), Positives = 130/264 (49%), Gaps = 14/264 (5%) Query: 317 WVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 + YT +RE ++Y L +TA + P S+ F Y + + Sbjct: 3617 YFYTCFLQNRERISQYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSI 3676 Query: 376 AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFK 432 +E PPGT VV +TA D DE ++R+ Y I + + S N G+++ +D Sbjct: 3677 SEASPPGTSVVKVTAIDKDEGTNSRVLYRIRHDASSANSDVFSINAETGVLSTQVFIDEY 3736 Query: 433 QERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + R + + V A D G S T V + I D N+ PVF N Y+ S+ E A G++V+ Sbjct: 3737 EYRAFTVIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVI 3796 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V+ATD+D GIN+++TY + IS + H F IN TG I+ N LDRE++ + L Sbjct: 3797 QVAATDADTGINSRLTYRI---ISGDEQGH----FAINASTGLISVNSALDRESIDSFRL 3849 Query: 550 TVTARDGGVPSLSDTTDVEISVVD 573 TV A + + ++T+ E VD Sbjct: 3850 TVGAFNDEALAFNNTSRREQRNVD 3873 Score = 116 bits (279), Expect = 3e-25 Identities = 74/249 (29%), Positives = 116/249 (46%), Gaps = 9/249 (3%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFY 258 F+ID ++GD+ V LD E +Y L ++A D R + + + + D NDNAP F Sbjct: 1218 FAIDPMTGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFK 1277 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 + + E+ P +++V+V+A D D G N ++Y++ +GNVD ID SG + Sbjct: 1278 KQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIV----SGNVDGAFVIDSSSGVI 1333 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 + +DRE +Y L V A DGG P AT Y + E+ Sbjct: 1334 KPAQDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPEN 1393 Query: 379 EPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 +PPG V+ ++ D D T N + + TS G++ LD + + Y Sbjct: 1394 QPPGQSVLKISVFDPDHAGNGQVAFTVNNNKFTVNDTS----GVLYTTHVLDRETKASYQ 1449 Query: 439 LTVSATDSG 447 LT++ATD G Sbjct: 1450 LTITATDKG 1458 Score = 99.1 bits (236), Expect = 4e-20 Identities = 65/199 (32%), Positives = 106/199 (53%), Gaps = 18/199 (9%) Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 I+V ++ I ATD+D G NSA+ Y I GN F++D+L+G +S LD E Sbjct: 225 ITVVTYFMLTIILATDSDRGINSALHYMIDSGNFGNSFTLDALTGSLSTTGPLDREVRAE 284 Query: 223 YRLVIRAQD--G----GSPSRSNTT-----QLLINIRDVNDNAPRFYTSLFQESVSENVP 271 Y L++ D G G P R + ++ I I DVND+ P F +++ + EN+ Sbjct: 285 YTLLVFVSDLQGNASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENIT 344 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP--ITIDPRSGWVYTSGQLDRETQ 329 +G +++ D D G N +++Y ++ +GN + P +++P SG + S + D +T Sbjct: 345 LGTVVLQPSCVDRDLGTNGQISYHIS----SGNSETPPRFSVNPSSGALSVSTEFDFDTG 400 Query: 330 AK-YQLLVTATDGGDPPRS 347 K Y L++TATD G+P S Sbjct: 401 RKSYSLVLTATDKGEPALS 419 Score = 95.1 bits (226), Expect = 7e-19 Identities = 71/248 (28%), Positives = 119/248 (47%), Gaps = 13/248 (5%) Query: 629 SFVIDPASGVIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 +F IDP +G IR LDRE+ + D+KA +D P+ S +V++++ D ND+ PV Sbjct: 1217 TFAIDPMTGDIRAVGLLDRETKLNYTLDVKATDVDP-VDPRWSAAVVYVEVLDSNDNAPV 1275 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 F+ + E+SP T+ ++ A D D G N + YSI G+ +F +++ G K Sbjct: 1276 FKKQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSSSGVIKP 1335 Query: 747 ELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 D+D E ++ Y L ++A SP L V+V I + DVNDN PV+ + Sbjct: 1336 AQ----DIDREKIQR-YLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASV 1390 Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863 ++ P ++ +D D Q NN +N+T+G + + L+ Sbjct: 1391 PENQPPGQSVLKISVFDPDHAGNGQVAFTVNNNK--FTVNDTSGVLYTTHVLDRETKASY 1448 Query: 864 TMEVSVTD 871 + ++ TD Sbjct: 1449 QLTITATD 1456 Score = 91.9 bits (218), Expect = 7e-18 Identities = 58/149 (38%), Positives = 79/149 (53%), Gaps = 9/149 (6%) Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 DS D I + D N+ APVF YT V ++ +G +V V ATD D GINA Sbjct: 40 DSDDDDDDDEDDIILDDVNDNAPVFSRPEGYTFEV-QEGGVGLSVGTVQATDRDSGINAA 98 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 YSL S VA + + F+I+ +TG I T+ LDRET + V ARD G P LS Sbjct: 99 TLYSLKS------VADYSK-FIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSA 151 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIME 592 + ++V D+ND+ P F Q+ Y+ + E Sbjct: 152 EVGIIVNVTDINDHRPAFSQRQYSVTVQE 180 Score = 90.2 bits (214), Expect = 2e-17 Identities = 68/218 (31%), Positives = 112/218 (51%), Gaps = 9/218 (4%) Query: 646 DRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 +RE ++ + L A + T P SS V+V + + D+ND P F+S ISE SP GT Sbjct: 3625 NRERISQYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISEASPPGT 3684 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 ++ ++ A D DEG N+ V Y I+ D S++ S ++ L T V +D E + + Sbjct: 3685 SVVKVTAIDKDEGTNSRVLYRIR-HDASSANSDVFSINAETGVLSTQVFID-EYEYRAFT 3742 Query: 765 LVIRA---ASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 +++ A SP L + V V + + DVNDN PV + + + +V A D Sbjct: 3743 VIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVAATD 3802 Query: 821 AD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 AD + +L YRI+SG+ +N +TG ++++ L+ Sbjct: 3803 ADTGINSRLTYRIISGDEQGHFAINASTGLISVNSALD 3840 Score = 86.6 bits (205), Expect = 3e-16 Identities = 63/191 (32%), Positives = 95/191 (49%), Gaps = 23/191 (12%) Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 + ATD+D ++ LHY I GN F++ + G ++ PLD + Y L V +D Sbjct: 236 ILATDSDRGINSALHYMIDSGNFGNSFTLDALTGS--LSTTGPLDREVRAEYTLLVFVSD 293 Query: 446 SGGRS-------DTAMVQ------INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 G + D+A+V I I+D N+ P F A Y+ + E+ +GT VL S Sbjct: 294 LQGNASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPS 353 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTV 551 D D+G N QI+Y +SS S +F +NP +GA++ + D +T Y L + Sbjct: 354 CVDRDLGTNGQISYHISSGNSET-----PPRFSVNPSSGALSVSTEFDFDTGRKSYSLVL 408 Query: 552 TARDGGVPSLS 562 TA D G P+LS Sbjct: 409 TATDKGEPALS 419 Score = 86.2 bits (204), Expect = 3e-16 Identities = 62/193 (32%), Positives = 97/193 (50%), Gaps = 22/193 (11%) Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 ++ ATDSD GIN+ + Y + S + F ++ TG+++T LDRE + Y L Sbjct: 235 IILATDSDRGINSALHYMIDS-------GNFGNSFTLDALTGSLSTTGPLDREVRAEYTL 287 Query: 550 TVTARD--G----GVPSLSDTT------DVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 V D G G+P L D+ +V I++ DVND+ P F Q +Y+ I E+ +G Sbjct: 288 LVFVSDLQGNASLGIP-LRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENITLG 346 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRES-VATHDL 655 T V Q D D+G NG+I Y + + E F ++P+SG + + D ++ ++ L Sbjct: 347 TVVLQPSCVDRDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSL 406 Query: 656 KAVAIDGGTPPQS 668 A D G P S Sbjct: 407 VLTATDKGEPALS 419 Score = 84.2 bits (199), Expect = 1e-15 Identities = 49/126 (38%), Positives = 72/126 (57%), Gaps = 3/126 (2%) Query: 563 DTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 D + +I + DVNDN PVF + + YT + E VG SV V ATD D G+N Y L Sbjct: 46 DDDEDDIILDDVNDNAPVFSRPEGYTFEVQEGG-VGLSVGTVQATDRDSGINAATLYSLK 104 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 + F+ID +GVI+T+ +LDRE+ +++ +A D G+P S+ V + + + DIN Sbjct: 105 SV-ADYSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDIN 163 Query: 682 DSPPVF 687 D P F Sbjct: 164 DHRPAF 169 Score = 82.6 bits (195), Expect = 4e-15 Identities = 59/160 (36%), Positives = 85/160 (53%), Gaps = 13/160 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATD---QAS---PVSDRLSSTATIHVNII-- 141 F +D +G+L T LDRE A YT+LV +D AS P+ D I V I Sbjct: 262 FTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQGNASLGIPLRDSAVVNVFIEVTITIS 321 Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN--TQMQ 199 D ND+ P+FS+ Y+V + E+I++ V+ + D D+G N I Y I GN T + Sbjct: 322 DVNDSPPEFSQAMYSVRIPENITL--GTVVLQPSCVDRDLGTNGQISYHISSGNSETPPR 379 Query: 200 FSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRS 238 FS++ SG +S+ D++ R SY LV+ A D G P+ S Sbjct: 380 FSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPALS 419 Score = 81.0 bits (191), Expect = 1e-14 Identities = 59/178 (33%), Positives = 83/178 (46%), Gaps = 18/178 (10%) Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID--G 662 ATD+D G+N +HY +D SF +D +G + T LDRE A + L D G Sbjct: 238 ATDSDRGINSALHYMID-SGNFGNSFTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQG 296 Query: 663 ----GTPPQSSTVI-----VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 G P + S V+ V I I D+NDSPP F + I EN +GT + + D Sbjct: 297 NASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVD 356 Query: 714 PDEGPNAVVHYSIKGGDDSN--SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D G N + Y I G+ FS+ G+ L + D+++ RK Y LV+ A Sbjct: 357 RDLGTNGQISYHISSGNSETPPRFSVNPSSGA----LSVSTEFDFDTGRKSYSLVLTA 410 Score = 70.9 bits (166), Expect = 1e-11 Identities = 54/186 (29%), Positives = 86/186 (46%), Gaps = 29/186 (15%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN++D D SPVF Y + E G++V+ ++ + G + Y+I Sbjct: 2565 INIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAG--TIIMYSI-------- 2614 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 Q+VF ID +G + T A LDRE Y + V+ATD + R+ Sbjct: 2615 -------------GSSQNVFSIDNLTGLVTTAAKLDRESRDDYVITVQATDNGQ--TPRV 2659 Query: 131 SSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 T+ + +++ D NDN P+F Y ++V+ED ++ + ++KA D D G N Y Sbjct: 2660 GYTSVV-IHVTDINDNAPKFQFPAPYKMTVNEDAALGTG--VGRVKAIDGDQGLNGMFEY 2716 Query: 190 AIIGGN 195 AI N Sbjct: 2717 AITHAN 2722 Score = 69.3 bits (162), Expect = 4e-11 Identities = 54/148 (36%), Positives = 78/148 (52%), Gaps = 24/148 (16%) Query: 15 DCNDHSPVFEMQQ-YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPE 73 D ND++PVF + Y V+EG G +V T++ATD+D G NA Y+++ V AD Sbjct: 56 DVNDNAPVFSRPEGYTFEVQEGGV-GLSVGTVQATDRDSGINAATLYSLKSV-AD----- 108 Query: 74 DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133 F ID ++G + T SLDRE + + V A D SP +LS+ Sbjct: 109 -------------YSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSP---QLSAE 152 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDE 161 I VN+ D ND+ P FS++ Y+V+V E Sbjct: 153 VGIIVNVTDINDHRPAFSQRQYSVTVQE 180 Score = 68.1 bits (159), Expect = 9e-11 Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 7/132 (5%) Query: 140 IIDD-NDNYPQFSE-KTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 I+DD NDN P FS + YT V E + ++ + ++ATD D G N+A Y++ Sbjct: 53 ILDDVNDNAPVFSRPEGYTFEVQEGGVGLS----VGTVQATDRDSGINAATLYSLKSVAD 108 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 +F IDS +G + +LD E + + A+D GSP S +++N+ D+ND+ P Sbjct: 109 YSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPA 168 Query: 257 FYTSLFQESVSE 268 F + +V E Sbjct: 169 FSQRQYSVTVQE 180 Score = 63.3 bits (147), Expect = 3e-09 Identities = 48/146 (32%), Positives = 65/146 (44%), Gaps = 7/146 (4%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTG 303 I + DVNDNAP F + +G S+ VQA D D G+NA Y++ DY+ Sbjct: 52 IILDDVNDNAPVFSRPEGYTFEVQEGGVGLSVGTVQATDRDSGINAATLYSLKSVADYSK 111 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + ID ++G + TS LDRETQ + + V A D G P SA Sbjct: 112 FI-----IDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHR 166 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLT 389 F QY V + E ++TLT Sbjct: 167 PAFSQRQYSVTVQEKRASHV-ILTLT 191 Score = 63.3 bits (147), Expect = 3e-09 Identities = 42/127 (33%), Positives = 66/127 (51%), Gaps = 8/127 (6%) Query: 675 IKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 I ++D+ND+ PVF + TF + E +G ++G ++A D D G NA YS+K D + Sbjct: 52 IILDDVNDNAPVFSRPEGYTFEVQEGG-VGLSVGTVQATDRDSGINAATLYSLKSVADYS 110 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNA 791 F ++++ G K T LD E+ + VI SP L +V + + VTD+ND+ Sbjct: 111 KFIIDSKTGVIK----TSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHR 166 Query: 792 PVMKDFQ 798 P Q Sbjct: 167 PAFSQRQ 173 Score = 50.4 bits (115), Expect = 2e-05 Identities = 42/153 (27%), Positives = 65/153 (42%), Gaps = 26/153 (16%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+ D ND++PV Y ASV E G +VL + D D N +V +T+ Sbjct: 1369 INIQDVNDNTPVLTSSTYTASVPENQPPGQSVLKISVFDPDHAGNGQVAFTVN------- 1421 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ++ SG L T LDRE A Y + + ATD+ V + Sbjct: 1422 ----------------NNKFTVNDTSGVLYTTHVLDRETKASYQLTITATDKGI-VENMT 1464 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 + I V+ +D ++ + Y++ D DI Sbjct: 1465 VGSHVIKVSAVDPDEG--SNGDILYSLQTDYDI 1495 Score = 44.4 bits (100), Expect = 0.001 Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 3/106 (2%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I I + D ND P F Y + E + GT VL D+D+G N ++ Y I Sbjct: 314 IEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGTNGQISYHISSGN 373 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVA 111 ++T P V F D GR L + D+ + A Sbjct: 374 SET--PPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPA 417 Score = 42.3 bits (95), Expect = 0.005 Identities = 37/162 (22%), Positives = 76/162 (46%), Gaps = 12/162 (7%) Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPLWNDVRVEILVTDV 787 S++F+++ G +A V ++D + + Y L ++A P W+ V + V D Sbjct: 1215 SHTFAIDPMTGDIRA--VGLLDRE---TKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDS 1269 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNET 845 NDNAPV K + + +V A D DV ++ Y I+SGN +++ + Sbjct: 1270 NDNAPVFKKQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSS 1329 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRL 886 +G + + ++ + + V DG + ++A +Q+++ + Sbjct: 1330 SGVIKPAQDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINI 1371 Score = 41.1 bits (92), Expect = 0.012 Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 1/58 (1%) Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSA 186 L++ AT+ +++ + NDN P+F+ K Y +V E + + ++ ++ A D D A NSA Sbjct: 913 LATNATVVIDLENVNDNTPEFTRKAYLFNVREGSYIDNEKIVGRVSAIDRDKDAENSA 970 Score = 40.3 bits (90), Expect = 0.022 Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 28/184 (15%) Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI- 767 I A D D G N+ +HY I G+ NSF+L+ GS L T LD E R +Y L++ Sbjct: 236 ILATDSDRGINSALHYMIDSGNFGNSFTLDALTGS----LSTTGPLDRE-VRAEYTLLVF 290 Query: 768 -------RAASPPLWND------VRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF 813 + PL + + V I ++DVND+ P Q +++ + +G Sbjct: 291 VSDLQGNASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFS--QAMYSVRIPENITLGTV 348 Query: 814 GRVPA---YDADVTDKLQYRILSGNNAN--LILLNETTGSMTLSPQLNTNV-PKLATMEV 867 P+ D ++ Y I SGN+ +N ++G++++S + + + K ++ + Sbjct: 349 VLQPSCVDRDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVL 408 Query: 868 SVTD 871 + TD Sbjct: 409 TATD 412 Score = 35.5 bits (78), Expect = 0.62 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL 45 +NV D NDH P F +QY +V+E +S +LTL Sbjct: 157 VNVTDINDHRPAFSQRQYSVTVQEKRAS-HVILTL 190 Score = 32.3 bits (70), Expect = 5.8 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQVGATDADVGLN----G 614 L+ V I + +VNDN P F ++ Y N+ E + + V +V A D D G Sbjct: 913 LATNATVVIDLENVNDNTPEFTRKAYLFNVREGSYIDNEKIVGRVSAIDRDKDAENSAYG 972 Query: 615 RIHY 618 RI Y Sbjct: 973 RIQY 976 >SB_15712| Best HMM Match : Cadherin (HMM E-Value=0) Length = 1075 Score = 277 bits (680), Expect = 7e-74 Identities = 244/890 (27%), Positives = 397/890 (44%), Gaps = 94/890 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREG---ASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 IN+ D +D F + YEA + + A S T L + + + Y + ++ Sbjct: 211 INITDVDDLPANFSQKLYEAHIDKNSPLAKSTTQPLAFTLVKVTVSTLSNLTYDVSILEG 270 Query: 68 DT------LNPEDAXXXXXXXXXXVQD----VFRIDGRSGALLTRASLDREKVARYTVLV 117 + L P ++ D +F I+G + + LDRE A++ + + Sbjct: 271 EANVPVMDLKPAESHFNVSGGNFTFFDSSGSMFSING-TNLRVGSTPLDRETAAQHILDI 329 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177 T+ + + + VN++D ND P F ++ VSV+E + V + AT Sbjct: 330 SLTEGGT-----IKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERL--GTVFLTVSAT 382 Query: 178 DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 D D GANSA+ Y+I GN + FSI++ +G +S+ K LD E Y L + AQDGG P Sbjct: 383 DGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPL 442 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 ++TT + I + D NDN P ++ Q S+SE I + V A D D G N L Y++ Sbjct: 443 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSI- 501 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP---PRSATATXXX 354 + G+ + D SG + +G L + Y ++V TDGG P R+ Sbjct: 502 ESGALGHFQIK---DWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVT 558 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPP--GTPVVTLTATDAD--EDNRLHYEITGGNTRG 410 + G+ V++ + + TPV T+ A+D D + RL Y I G G Sbjct: 559 PKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPVATVIASDKDIGANGRLMYSIESG-AHG 617 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPV 468 F I + G I++A L + Q Y++ V+ TD G + AMV I++T P Sbjct: 618 HFQI-KDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PK 670 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQQFVIN 527 N Y SV E V+ + +S ++ T+ SS F IN Sbjct: 671 PRNLTYDVSVLE-GEANVQVMDLKPAESHFNMSGGNFTFFDSS----------GSMFSIN 719 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 T + LDRET + ++L ++ +GG ++ V ++V+D+ND P+F+ + Sbjct: 720 -GTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFN 776 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 ++ E +GT V ATD D G N + Y + + E S ++ Sbjct: 777 VSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEAVS----------------NK 820 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 S+ + DL +A+ V + + DIND P+F+S ++E +GT Sbjct: 821 NSLISEDLSYIALQ-----------VTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFL 869 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A D D G N+ + YSI G++ FS+ + G+ + LD E+ R +Y L + Sbjct: 870 TVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTV 924 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV- 823 A PPL + V I V D NDN PV++D I + + P V A D D+ Sbjct: 925 MAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIG 984 Query: 824 -TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +L Y I SG + + + + ++G+++L+ L+ N + V+VTDG Sbjct: 985 ANGRLMYSIESGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1034 Score = 216 bits (528), Expect = 2e-55 Identities = 232/792 (29%), Positives = 349/792 (44%), Gaps = 82/792 (10%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FRI+ +G L+ +LDRE + ++ AS S + S TA + I D NDN P Sbjct: 58 FRINSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAIL--TITDINDNAPA 115 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F TVS E+ + +A + ATDAD N+ I + I+ GN FSID ++GD+ Sbjct: 116 FQNTPLTVSCSENRPI--GLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDI 173 Query: 210 SLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVS 267 ++ K LDYE R Y L I A + + + ++ INI DV+D F L++ + Sbjct: 174 TISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHID 233 Query: 268 ENVPIGYSIVRVQAY---DADEGVNAELTYTMTDKDYTGNV---DLP------------I 309 +N P+ S + A+ + LTY ++ + NV DL Sbjct: 234 KNSPLAKSTTQPLAFTLVKVTVSTLSNLTYDVSILEGEANVPVMDLKPAESHFNVSGGNF 293 Query: 310 TIDPRSGWVYT---------SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 T SG +++ S LDRET A++ L ++ T+GG T Sbjct: 294 TFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVT--VNVLDIN 351 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418 F + V + E E GT +T++ATD D ++ L Y I GN G FSI N Sbjct: 352 DETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSI--NN 409 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G I+VA+ LD + +Y LTV A D G + T V I + DAN+ PV ++A Sbjct: 410 KTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQV 469 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E A I T V V A+D D+G N ++ YS+ S A+ H + + +GAI+ Sbjct: 470 SLSETAEIDTPVATVIASDKDIGANGRLMYSIES----GALGHFQ---IKDWSSGAISLA 522 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANI----M 591 +L + Y++ V DGG P+L V I V N L AN+ + Sbjct: 523 GMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVSVLEGEANVQVMDL 582 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESV 650 + A + T V+ V A+D D+G NGR+ Y ++ G F I D +SG I L Sbjct: 583 KTAEIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQR 640 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + + DGG+P S +V I D+ P LT+ +S GE Sbjct: 641 NNYIVVVNVTDGGSPALKSRAMVVI---DVTPKP-----RNLTYDVS------VLEGEAN 686 Query: 711 AHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 D P A H+++ GG+ + +S S+ + G++ V LD E+ + + Sbjct: 687 VQVMDLKP-AESHFNMSGGNFTFFDSSGSMFSINGTNLR--VGSTPLDRETAAQHILDIS 743 Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDAD--V 823 + V+V + V D+ND P+ + F + N + V F V A D D Sbjct: 744 LTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGA 801 Query: 824 TDKLQYRILSGN 835 L Y I GN Sbjct: 802 NSALTYSIAVGN 813 Score = 213 bits (520), Expect = 2e-54 Identities = 209/676 (30%), Positives = 304/676 (44%), Gaps = 85/676 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PV + + S+ E A T V T+ A+D+DIG N + Y+IE Sbjct: 450 IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 502 Query: 71 NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F+I D SGA+ L + Y V+V TD SP Sbjct: 503 -------------SGALGHFQIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 546 Query: 130 LSSTATIHVNIIDDNDNYPQ---FSEKTYTVSV-DEDISVTDNPVIAKIKATDADVGANS 185 L S A + +++ N E V V D + D PV A + A+D D+GAN Sbjct: 547 LKSRAIVVIDVTPKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPV-ATVIASDKDIGANG 605 Query: 186 AIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + Y+I G F I DS SG +SL L Y Q +Y +V+ DGGSP+ + ++ Sbjct: 606 RLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVV 664 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I++ PR T + SV E G + V+V E T D +G+ Sbjct: 665 IDVTP----KPRNLT--YDVSVLE----GEANVQVMDLKPAESHFNMSGGNFTFFDSSGS 714 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + + R G S LDRET A++ L ++ T+GG T Sbjct: 715 MFSINGTNLRVG----STPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPL- 769 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422 F + V + E E GT +T++ATD D ++ L Y I GN +++++N L Sbjct: 770 -FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEE---AVSNKNS--L 823 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 I+ ++ Y+ V +N+ D N+ P+F++ + SV E Sbjct: 824 IS--------EDLSYI-------------ALQVTVNVLDINDETPLFQSPSFNVSVNEIE 862 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +GT L VSATD D G N+ +TYS+ A + + F IN +TGAI+ K LDRE Sbjct: 863 RLGTVFLTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRE 915 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T Y LTV A+DGG P L+ TT V I V D NDN PV + + ++ E A + T V+ Sbjct: 916 TRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVAT 975 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAID 661 V A+D D+G NGR+ Y ++ G F I D +SG I L + + D Sbjct: 976 VIASDKDIGANGRLMYSIE--SGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTD 1033 Query: 662 GGTPPQSSTVIVHIKI 677 GG+P S +V I + Sbjct: 1034 GGSPALKSRAMVVIDV 1049 Score = 210 bits (513), Expect = 1e-53 Identities = 220/794 (27%), Positives = 346/794 (43%), Gaps = 95/794 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P F+ S E G TV TL ATD D NA + + I V+ + Sbjct: 104 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI--VSGNE- 160 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 + F ID +G + LD E R YT+ + A + + + Sbjct: 161 ----------------GEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDL--M 202 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI----SVTDNPVIAKIKATDA------ 179 L S + +NI D +D FS+K Y +D++ S T +K T + Sbjct: 203 LQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPLAKSTTQPLAFTLVKVTVSTLSNLT 262 Query: 180 -DVG-----ANSAI--------RYAIIGGN------TQMQFSIDSLSGDVSLVKTLDYEQ 219 DV AN + + + GGN + FSI+ + V LD E Sbjct: 263 YDVSILEGEANVPVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGST-PLDRET 321 Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 + L I +GG + ++ +N+ D+ND P F + F SV+E +G + V Sbjct: 322 AAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTV 379 Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 A D D G N+ LTY++ GN + +I+ ++G + + QLDRET+ +Y L V A Sbjct: 380 SATDGDAGANSALTYSIA----VGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQ 435 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397 DGG+PP ++T +V L+E TPV T+ A+D D + Sbjct: 436 DGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANG 495 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMV 455 RL Y I G G F I + G I++A L + Q Y++ V+ TD G + A+V Sbjct: 496 RLMYSIESG-ALGHFQIKDWSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIV 553 Query: 456 QINIT----DANNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 I++T + + V E A + A I T V V A+D D+G N ++ YS+ Sbjct: 554 VIDVTPKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPVATVIASDKDIGANGRLMYSI-- 611 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 E+ AH Q + + +GAI+ +L + Y++ V DGG P+L V Sbjct: 612 ----ESGAHGHFQ-IKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMV--- 663 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V+DV P + Y +++E V + ++ ++G D GS Sbjct: 664 VIDVT---PKPRNLTYDVSVLEGE-ANVQVMDLKPAESHFNMSGGNFTFFD----SSGSM 715 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 + + + LDRE+ A H L +GGT V V + + DIND P+F+S Sbjct: 716 FSINGTNLRVGSTPLDRETAAQHILDISLTEGGT--IKGFVKVTVNVLDINDETPLFQSP 773 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD---SNSFSLETRQGSDKAE 747 ++E +GT + A D D G N+ + YSI G++ SN SL + S A Sbjct: 774 SFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEAVSNKNSLISEDLSYIAL 833 Query: 748 LVT--MVDLDYESP 759 VT ++D++ E+P Sbjct: 834 QVTVNVLDINDETP 847 Score = 175 bits (427), Expect = 3e-43 Identities = 179/660 (27%), Positives = 289/660 (43%), Gaps = 61/660 (9%) Query: 255 PRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P F + + + + E N G I R+ A G N +TY++ D + I+ Sbjct: 12 PTFGSPFWSDVLPEVNTTAGTIITRLTA----TGGNGTITYSLEDIAHPW-----FRINS 62 Query: 314 RSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 +G + + LDRE L D + T F Sbjct: 63 STGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNTPLT 122 Query: 373 VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 V +E+ P G V TLTATDAD + + I GN FSI G IT+++PLD Sbjct: 123 VSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGD--ITISKPLD 180 Query: 431 FKQ-ERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG- 485 ++ R Y L +SA ++ +V INITD ++ F Y A + +++P+ Sbjct: 181 YENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPLAK 240 Query: 486 --TTVLVVSATDSDVGINAQITYSLS---SEIS------NEAVAHHD---QQFVINPQTG 531 T L + V + +TY +S E + A +H + F +G Sbjct: 241 STTQPLAFTLVKVTVSTLSNLTYDVSILEGEANVPVMDLKPAESHFNVSGGNFTFFDSSG 300 Query: 532 AITT---------NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 ++ + + LDRET + ++L ++ +GG ++ V ++V+D+ND P+F+ Sbjct: 301 SMFSINGTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQ 358 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 + ++ E +GT V ATD D G N + Y + EEG F I+ +G I Sbjct: 359 SPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AVGNEEGFFSINNKTGAISVA 417 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV + + +SE + I Sbjct: 418 KQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI 477 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 T + + A D D G N + YSI+ G F ++ S L M L Y + R Sbjct: 478 DTPVATVIASDKDIGANGRLMYSIESG-ALGHFQIKD-WSSGAISLAGM--LSY-NQRNN 532 Query: 763 YELVIR---AASPPLWNDVRVEILVTD-----VNDNAPVMKDFQIIFNNYKDCFPVGPFG 814 Y +V+ SP L + V I VT +D + + + + + K P Sbjct: 533 YIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPVA 592 Query: 815 RVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 V A D D+ +L Y I SG + + + + ++G+++L+ L+ N + V+VTDG Sbjct: 593 TVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 652 Score = 87.8 bits (208), Expect = 1e-16 Identities = 74/240 (30%), Positives = 111/240 (46%), Gaps = 14/240 (5%) Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 AP +P+ + V + + TT + + G N ITYSL E +AH F Sbjct: 10 APPTFGSPFWSDVLPE--VNTTAGTIITRLTATGGNGTITYSL------EDIAH--PWFR 59 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQ 584 IN TG + NK LDRE M L ++ S S + I ++ D+NDN P F+ Sbjct: 60 INSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNT 119 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 T + E+ +G +V+ + ATDAD N I + + E +F ID +G I +K Sbjct: 120 PLTVSCSENRPIGLTVATLTATDADATTNAIITFVI-VSGNEGEAFSIDKVTGDITISKP 178 Query: 645 LDRES-VATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LD E+ + L A++ T S +V I I D++D P F +I +NSP+ Sbjct: 179 LDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPL 238 Score = 74.1 bits (174), Expect = 1e-12 Identities = 60/182 (32%), Positives = 92/182 (50%), Gaps = 17/182 (9%) Query: 162 DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221 +++ T +I ++ AT G N I Y++ F I+S +GD+ + KTLD E + Sbjct: 25 EVNTTAGTIITRLTAT----GGNGTITYSL-EDIAHPWFRINSSTGDLIVNKTLDREAMG 79 Query: 222 ----SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 S R + A D S S+ + T +L I D+NDNAP F + S SEN PIG ++ Sbjct: 80 NGLGSLRFEVYASD--SSSQGSLTAIL-TITDINDNAPAFQNTPLTVSCSENRPIGLTVA 136 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLV 336 + A DAD NA +T+ + +GN +ID +G + S LD E + Y L + Sbjct: 137 TLTATDADATTNAIITFVIV----SGNEGEAFSIDKVTGDITISKPLDYENGPRVYTLNI 192 Query: 337 TA 338 +A Sbjct: 193 SA 194 Score = 52.0 bits (119), Expect = 7e-06 Identities = 51/206 (24%), Positives = 93/206 (45%), Gaps = 18/206 (8%) Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 +PP F S + + E + TT G I G N + YS++ D ++ + R Sbjct: 10 APPTFGSPFWSDVLPE---VNTTAGTIITRLTATGGNGTITYSLE--DIAHPWF---RIN 61 Query: 743 SDKAELVTMVDLDYESPRK---KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI 799 S +L+ LD E+ + A+ + + +TD+NDNAP ++ + Sbjct: 62 SSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNTPL 121 Query: 800 IFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLN 856 + ++ P+G + A DAD T + + I+SGN +++ TG +T+S L+ Sbjct: 122 TVSCSENR-PIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDITISKPLD 180 Query: 857 -TNVPKLATMEVSVTDGVNEIKAMMQ 881 N P++ T+ +S + N M+Q Sbjct: 181 YENGPRVYTLNISAMN--NHTDLMLQ 204 >SB_36047| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 980 Score = 274 bits (673), Expect = 5e-73 Identities = 211/667 (31%), Positives = 315/667 (47%), Gaps = 39/667 (5%) Query: 90 FRIDGRSGALLTRASLDREKVAR----YTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 FRI+ +G L+ +LDRE + + V A+D +SP + + IID ND Sbjct: 74 FRINSSTGDLIVNKTLDREAMGSGDGSFRFEVYASDGSSP-----QGSLRAFLTIIDIND 128 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P F T S ED V PV+ + ATDAD N+ I + I+ GN FSID + Sbjct: 129 NAPAFQNTPLTKSCSEDTPV-GFPVVT-VTATDADATTNAIITFVIVSGNEGEAFSIDKV 186 Query: 206 SGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQ 263 +GD+++ K LDYE R Y L I A + + + ++ IN+ DV+D F L++ Sbjct: 187 TGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINVTDVDDLPANFSQKLYE 246 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSG 322 + +N P+G I +V A D D +NA + Y++ D D G I+ SG V G Sbjct: 247 AHIDKNSPLGSFITQVHAEDMDS-LNAPVEYSIYPDSDPDGL----FAINKTSGAVTVDG 301 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 L Y L+V A PP + G+ V++ + + Sbjct: 302 NLKNGV---YSLIVNAKSTTQPPAFTLVKVTVGPLPNLTYAVTVLEGEANVQVMDLQVTV 358 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVL 439 + + T + H+ +GG S+ S +G L + PLD + ++VL Sbjct: 359 ETRDSYSYTKRALPAKSHFNASGGTFTFFGSSGSMFSIDGAKLKVGSTPLDRETAAQHVL 418 Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 +S T+ G V +N+ D N+ P F++ + SV E +GT +L V ATD D G Sbjct: 419 DISLTEGGTVKGFVKVTVNVLDINDDRPSFQSPSFNVSVNEIERLGTVILTVFATDGDAG 478 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 N +TYS+S+ NE + F IN +TGAI+ K LDRET Y LTV A+DGG P Sbjct: 479 ANGTLTYSISA--GNE-----EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP 531 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 L+ TT V I V D NDN PV + + ++ E A + T V+ V A+D D+G NGR+ Y Sbjct: 532 PLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYS 591 Query: 620 LDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 ++ G F I D +SG I L + + + DGG+ S IV I + Sbjct: 592 IE--SGAHGHFQIKDSSSGAISVAGVLSYKQWHNYTVVVKVTDGGSLALESRAIVLIDVT 649 Query: 679 DI--NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 N + PVF S + +++ + + A D D G N VV Y I+ +D++ F Sbjct: 650 STTENRNGPVFASVQYIGGVYKDTSFDFPVLTVTATDSDTGVNGVVEYRIR--EDTDLFY 707 Query: 737 LETRQGS 743 +E G+ Sbjct: 708 VEPTSGT 714 Score = 210 bits (513), Expect = 1e-53 Identities = 206/715 (28%), Positives = 327/715 (45%), Gaps = 66/715 (9%) Query: 162 DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221 +++ T I + ATD D G N I Y++ N F I+S +GD+ + KTLD E + Sbjct: 40 EVNTTAGTNITRFTATDGD-GDN--ISYSL-QSNAHPWFRINSSTGDLIVNKTLDREAMG 95 Query: 222 S----YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 S +R + A DG SP S + + I D+NDNAP F + +S SE+ P+G+ +V Sbjct: 96 SGDGSFRFEVYASDGSSPQGS--LRAFLTIIDINDNAPAFQNTPLTKSCSEDTPVGFPVV 153 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLV 336 V A DAD NA +T+ + +GN +ID +G + S LD E + Y L + Sbjct: 154 TVTATDADATTNAIITFVIV----SGNEGEAFSIDKVTGDITISKPLDYENGPRVYTLNI 209 Query: 337 TATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 +A + D + F YE + ++ P G+ + + A D D Sbjct: 210 SAMNNHTDLMLQSFGVVTINVTDVDDLPANFSQKLYEAHIDKNSPLGSFITQVHAEDMDS 269 Query: 396 DNR-LHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA 453 N + Y I + G F+I +G +TV L + Y L V+A + Sbjct: 270 LNAPVEYSIYPDSDPDGLFAINKTSGA--VTVDGNL---KNGVYSLIVNAKSTTQPPAFT 324 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 +V++ + P+ N Y +V E V D V + + +YS + + Sbjct: 325 LVKVTV------GPL-PNLTYAVTVLEGEAN------VQVMDLQVTVETRDSYSYTKR-A 370 Query: 514 NEAVAHHDQQ---FVINPQTGA---ITTNKL------LDRETMSGYLLTVTARDGGVPSL 561 A +H + F +G+ I KL LDRET + ++L ++ +GG ++ Sbjct: 371 LPAKSHFNASGGTFTFFGSSGSMFSIDGAKLKVGSTPLDRETAAQHVLDISLTEGG--TV 428 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 V ++V+D+ND+ P F+ + ++ E +GT + V ATD D G NG + Y + Sbjct: 429 KGFVKVTVNVLDINDDRPSFQSPSFNVSVNEIERLGTVILTVFATDGDAGANGTLTYSIS 488 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 + EEG F I+ +G I K LDRE+ + L +A DGG PP +ST V I++ D N Sbjct: 489 AGN-EEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAN 547 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D+PPV + + +SE + I T + + A D D G N + YSI+ G + + + Sbjct: 548 DNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH---FQIKD 604 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILV----TDVNDNAPVMKD 796 S A V V L Y+ Y +V++ L + R +L+ T N N PV Sbjct: 605 SSSGAISVAGV-LSYKQWHN-YTVVVKVTDGGSLALESRAIVLIDVTSTTENRNGPVFAS 662 Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM 849 Q I YKD P V A D+D V ++YRI + +L + T+G++ Sbjct: 663 VQYIGGVYKDTSFDFPVLTVTATDSDTGVNGVVEYRI--REDTDLFYVEPTSGTI 715 Score = 190 bits (462), Expect = 2e-47 Identities = 185/672 (27%), Positives = 296/672 (44%), Gaps = 59/672 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + ++D ND++P F+ S E G V+T+ ATD D NA + + I V+ + Sbjct: 121 LTIIDINDNAPAFQNTPLTKSCSEDTPVGFPVVTVTATDADATTNAIITFVI--VSGNE- 177 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 + F ID +G + LD E R YT+ + A + + + Sbjct: 178 ----------------GEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLM-- 219 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S + +N+ D +D FS+K Y +D++ + I ++ A D D N+ + Y Sbjct: 220 LQSFGVVTINVTDVDDLPANFSQKLYEAHIDKNSPL--GSFITQVHAEDMD-SLNAPVEY 276 Query: 190 AII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +I + F+I+ SG V++ L + Y L++ A+ P ++ + Sbjct: 277 SIYPDSDPDGLFAINKTSGAVTVDGNL---KNGVYSLIVNAKSTTQPPAFTLVKVTVGPL 333 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD-ADEGVNAELTYTMTDKDYT--GNV 305 N T L E+ + + + ++ +Y + A+ + + +T G+ Sbjct: 334 P---NLTYAVTVLEGEANVQVMDLQVTVETRDSYSYTKRALPAKSHFNASGGTFTFFGSS 390 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 +ID V S LDRET A++ L ++ T+GG T Sbjct: 391 GSMFSIDGAKLKV-GSTPLDRETAAQHVLDISLTEGGTVKGFVKVTVNVLDINDDRPS-- 447 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F + V + E E GT ++T+ ATD D + L Y I+ GN G FSI N G I Sbjct: 448 FQSPSFNVSVNEIERLGTVILTVFATDGDAGANGTLTYSISAGNEEGFFSIN--NKTGAI 505 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481 +VA+ LD + +Y LTV A D G + T V I + DAN+ PV ++A S+ E Sbjct: 506 SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSET 565 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A I T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ +L Sbjct: 566 AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISVAGVLSY 618 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTS 599 + Y + V DGG +L V I V +N PVF Y + +D Sbjct: 619 KQWHNYTVVVKVTDGGSLALESRAIVLIDVTSTTENRNGPVFASVQYIGGVYKDTSFDFP 678 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKAL-DRESVATHDLKA 657 V V ATD+D G+NG + Y + RE+ F ++P SG IRT D++ + Sbjct: 679 VLTVTATDSDTGVNGVVEYRI----REDTDLFYVEPTSGTIRTADVFADKDEGQSFSFSV 734 Query: 658 VAIDGGTPPQSS 669 A D GTPP+ + Sbjct: 735 QASDKGTPPKET 746 Score = 169 bits (410), Expect = 4e-41 Identities = 185/663 (27%), Positives = 290/663 (43%), Gaps = 56/663 (8%) Query: 251 NDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N P F + ++ + E N G +I R A D D G N ++Y++ N Sbjct: 23 NGAPPTFISPIWSDVFPEVNTTAGTNITRFTATDGD-GDN--ISYSLQS-----NAHPWF 74 Query: 310 TIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I+ +G + + LDRE ++ V A+DG P S A Sbjct: 75 RINSSTGDLIVNKTLDREAMGSGDGSFRFEVYASDGSSPQGSLRA--FLTIIDINDNAPA 132 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLI 423 F +ED P G PVVT+TATDAD + + I GN FSI G I Sbjct: 133 FQNTPLTKSCSEDTPVGFPVVTVTATDADATTNAIITFVIVSGNEGEAFSIDKVTGD--I 190 Query: 424 TVAQPLDFKQERR-YVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVF 479 T+++PLD++ R Y L +SA ++ +V IN+TD ++ F Y A + Sbjct: 191 TISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINVTDVDDLPANFSQKLYEAHID 250 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 +++P+G+ + V A D D +NA + YS+ + + D F IN +GA+T + L Sbjct: 251 KNSPLGSFITQVHAEDMD-SLNAPVEYSIYPD------SDPDGLFAINKTSGAVTVDGNL 303 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 Y L V A+ P T V+++V + + AN+ L T Sbjct: 304 KNGV---YSLIVNAKSTTQPPAF--TLVKVTVGPLPNLTYAVTVLEGEANVQVMDLQVTV 358 Query: 600 VSQVGATDADVGLNGRIHYELDPKD----REEGS-FVIDPASGVIRTNKALDRESVATHD 654 ++ + L + H+ GS F ID A + + LDRE+ A H Sbjct: 359 ETRDSYSYTKRALPAKSHFNASGGTFTFFGSSGSMFSIDGAKLKVGSTP-LDRETAAQHV 417 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L +GGT V V + + DIND P F+S ++E +GT I + A D Sbjct: 418 LDISLTEGGTV--KGFVKVTVNVLDINDDRPSFQSPSFNVSVNEIERLGTVILTVFATDG 475 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 D G N + YSI G++ FS+ + G+ + LD E+ R +Y L + A Sbjct: 476 DAGANGTLTYSISAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGE 530 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829 PPL + V I V D NDN PV++D I + + P V A D D+ +L Y Sbjct: 531 PPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMY 590 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN---EIKAMMQLSVRL 886 I SG + + + + ++G+++++ L+ T+ V VTDG + E +A++ + V Sbjct: 591 SIESGAHGHFQIKDSSSGAISVAGVLSYKQWHNYTVVVKVTDGGSLALESRAIVLIDVTS 650 Query: 887 ITE 889 TE Sbjct: 651 TTE 653 >SB_9756| Best HMM Match : Cadherin (HMM E-Value=0) Length = 608 Score = 268 bits (657), Expect = 4e-71 Identities = 192/598 (32%), Positives = 303/598 (50%), Gaps = 60/598 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+ P FE Y SV E A+ GT ++ L +TD D G+NA V Y L+ + Sbjct: 56 ITVLDENDNKPRFEAGAYNVSVYENATIGTVIVRLTSTDADQGRNAHVIYN--LLAGSGI 113 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 FR+D +G + + LDRE + +++ V +D P+ Sbjct: 114 G-----------------TFRVDNTTGEITLQKPLDREVMDFFSLFVSVSD---PL---F 150 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ + ++I+D N+ P F+ + Y V + E +V ++ + +TD D+G N+A+RYA Sbjct: 151 SAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLV--VTSTDQDIGKNAAVRYA 208 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LLINIR 248 I+ G+ F+++ G ++L K+LD E+ ++ L I A D G PS T+ ++I++ Sbjct: 209 IVDGDPDGYFAVNDY-GVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVV 267 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDL 307 D NDN P F SL++ ++ EN G S++ V+A D D + N EL Y + GN Sbjct: 268 DTNDNNPIFELSLYETTILENTTAGSSVLEVRADDGDSQSSNKELRYVIL-----GNCT- 321 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQL-----LVTATDGGDPPRSATATXXXXXXXXXXX 362 ID SG +YT+ +D E Q Y+ ++ ATD G PRSA A Sbjct: 322 DWHIDSLSGVIYTNNSVDYERQRVYEFQDFSFVLIATDNGTSPRSAHARVHITVNDVNDN 381 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420 F P Y+V ++E P G ++ LT +D D E+++L+ + G+ F +++ Sbjct: 382 RPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFLSNS--- 438 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYTA 476 G I++A+ LD+++ + Y LTV A DSG A V I I D N+ PVF Y A Sbjct: 439 GEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYEA 498 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V E+ G V+ V A D+D N ++ YS+ ++ +F +N TG I + Sbjct: 499 WVLENITAGQFVVQVKAKDADYQQNGRLVYSM---------VRNNSKFRVNETTGEIYLS 549 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LD E Y+ + A D GV S +T V + V+DVNDN P F + LY + + E++ Sbjct: 550 ESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENS 607 Score = 258 bits (632), Expect = 5e-68 Identities = 190/617 (30%), Positives = 299/617 (48%), Gaps = 42/617 (6%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L T SLDRE ++ Y ++V+A + + +++ I++ ++D+NDN P+F Y VS Sbjct: 20 LYTTRSLDRENISYYLLMVRARNIDEHAQEAITA---INITVLDENDNKPRFEAGAYNVS 76 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 V E+ ++ VI ++ +TDAD G N+ + Y ++ G+ F +D+ +G+++L K LD E Sbjct: 77 VYENATI--GTVIVRLTSTDADQGRNAHVIYNLLAGSGIGTFRVDNTTGEITLQKPLDRE 134 Query: 219 QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278 + + L + D P S + I+I DVN+ P F + +SE +G +++ Sbjct: 135 VMDFFSLFVSVSD---PLFSAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLV 191 Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 V + D D G NA + Y + D D G + G + + LD E + L +TA Sbjct: 192 VTSTDQDIGKNAAVRYAIVDGDPDGYFAVN-----DYGVITLTKSLDSERNTTFNLTITA 246 Query: 339 TDGGDPP-RSAT-ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED 396 D G P +AT A F YE + E+ G+ V+ + A D D Sbjct: 247 HDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYETTILENTTAGSSVLEVRADDGDSQ 306 Query: 397 N---RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL-----TVSATDSGG 448 + L Y I G T S G+I +D++++R Y + ATD+G Sbjct: 307 SSNKELRYVILGNCTDWHIDSLS----GVIYTNNSVDYERQRVYEFQDFSFVLIATDNGT 362 Query: 449 --RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 RS A V I + D N+ PVFE Y V E AP+G T+L ++ +D+D N+Q+ Sbjct: 363 SPRSAHARVHITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLNL 422 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT-- 564 + S N F+ N +G I+ + LD E + Y LTV A D G P L Sbjct: 423 RVVSGDPNSTF------FLSN--SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKP 474 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 +V I + D NDN+PVF + LY A ++E+ G V QV A DAD NGR+ Y + Sbjct: 475 ANVVIRIRDDNDNQPVFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMV--- 531 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 R F ++ +G I +++LD E + +A D G P+SS+ V + + D+ND+ Sbjct: 532 RNNSKFRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNV 591 Query: 685 PVFESDCLTFYISENSP 701 P F+ + ENSP Sbjct: 592 PTFDRFLYKSTVRENSP 608 Score = 245 bits (600), Expect = 3e-64 Identities = 193/598 (32%), Positives = 291/598 (48%), Gaps = 46/598 (7%) Query: 315 SGWV--YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 +GW+ YT+ LDRE + Y L+V A + + + A F G Y Sbjct: 15 NGWLGLYTTRSLDRENISYYLLMVRARNIDEHAQEAITAINITVLDENDNKPRFEAGAYN 74 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLD 430 V + E+ GT +V LT+TDAD+ H Y + G+ G F + N G IT+ +PLD Sbjct: 75 VSVYENATIGTVIVRLTSTDADQGRNAHVIYNLLAGSGIGTFRV--DNTTGEITLQKPLD 132 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + + L VS +D + V I+I D N Y PVF Y + E + +GTT+LV Sbjct: 133 REVMDFFSLFVSVSDPLFSAYQG-VTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLV 191 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V++TD D+G NA + Y++ D F +N G IT K LD E + + LT Sbjct: 192 VTSTDQDIGKNAAVRYAIVD-------GDPDGYFAVNDY-GVITLTKSLDSERNTTFNLT 243 Query: 551 VTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 +TA D G+PSL T V I VVD NDN P+F+ LY I+E+ G+SV +V A D Sbjct: 244 ITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYETTILENTTAGSSVLEVRADDG 303 Query: 609 DV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK-----AVAIDG 662 D N + Y + + + ID SGVI TN ++D E ++ + +A D Sbjct: 304 DSQSSNKELRYVILGNCTD---WHIDSLSGVIYTNNSVDYERQRVYEFQDFSFVLIATDN 360 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 GT P+S+ VHI + D+ND+ PVFE +SE +P+G TI + D D N+ + Sbjct: 361 GTSPRSAHARVHITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQL 420 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVR- 779 + + GD +++F L S+ E+ LDYE + Y L + A + P+ ++ Sbjct: 421 NLRVVSGDPNSTFFL-----SNSGEISIARKLDYER-LQMYNLTVVAWDSGKPVLQSLKP 474 Query: 780 --VEILVTDVNDNAPVMKDFQIIFNNYK-DCFPVGPFG-RVPAYDADVTD--KLQYRILS 833 V I + D NDN PV + ++ + + G F +V A DAD +L Y ++ Sbjct: 475 ANVVIRIRDDNDNQPVFS--RDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMVR 532 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 N+ +NETTG + LS L+ K + +D E K+ SVR+I ++ Sbjct: 533 NNSK--FRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKS-SSTSVRVIVMDV 587 Score = 226 bits (553), Expect = 2e-58 Identities = 176/601 (29%), Positives = 282/601 (46%), Gaps = 43/601 (7%) Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 ++LD E + Y L++RA++ ++ T + I + D NDN PRF + SV EN I Sbjct: 24 RSLDRENISYYLLMVRARNIDEHAQEAITAINITVLDENDNKPRFEAGAYNVSVYENATI 83 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G IVR+ + DAD+G NA + Y + G +D +G + LDRE + Sbjct: 84 GTVIVRLTSTDADQGRNAHVIYNLLAGSGIGT----FRVDNTTGEITLQKPLDREVMDFF 139 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 L V+ + DP SA F P +Y VE++E GT ++ +T+TD Sbjct: 140 SLFVSVS---DPLFSAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLVVTSTD 196 Query: 393 AD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450 D ++ + Y I G+ G F++ N G+IT+ + LD ++ + LT++A D G S Sbjct: 197 QDIGKNAAVRYAIVDGDPDGYFAV---NDYGVITLTKSLDSERNTTFNLTITAHDKGMPS 253 Query: 451 ----DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQIT 505 A+V I++ D N+ P+FE + Y ++ E+ G++VL V A D D N ++ Sbjct: 254 LETATRAIVVIDVVDTNDNNPIFELSLYETTILENTTAGSSVLEVRADDGDSQSSNKELR 313 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY-----LLTVTARDGGVPS 560 Y + ++ + I+ +G I TN +D E Y + A D G Sbjct: 314 YVILGNCTD---------WHIDSLSGVIYTNNSVDYERQRVYEFQDFSFVLIATDNGTSP 364 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 S V I+V DVNDN PVF+ Y + E A VG ++ ++ +D D N +++ + Sbjct: 365 RSAHARVHITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRV 424 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS--TVIVHIKIE 678 D F+ + SG I + LD E + ++L VA D G P S V I+I Sbjct: 425 VSGDPNSTFFLSN--SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIR 482 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D ND+ PVF D ++ EN G + +++A D D N + YS+ +++ F + Sbjct: 483 DDNDNQPVFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMV--RNNSKFRVN 540 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKD 796 G E+ LD+E ++ +I + S P + V ++V DVNDN P Sbjct: 541 ETTG----EIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDR 596 Query: 797 F 797 F Sbjct: 597 F 597 Score = 126 bits (305), Expect = 2e-28 Identities = 83/261 (31%), Positives = 130/261 (49%), Gaps = 25/261 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PVFE Y+ V E A G T+L L +D D +N+++ + +V+ D Sbjct: 373 ITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLN--LRVVSGDP- 429 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F + SG + LD E++ Y + V A D PV L Sbjct: 430 ----------------NSTFFLSN-SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSL 472 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 A + + I DDNDN P FS Y V E+I T + ++KA DAD N + Y+ Sbjct: 473 KP-ANVVIRIRDDNDNQPVFSRDLYEAWVLENI--TAGQFVVQVKAKDADYQQNGRLVYS 529 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 ++ N++ F ++ +G++ L ++LD+E+ + Y I A D G +S++T + + + DV Sbjct: 530 MVRNNSK--FRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDV 587 Query: 251 NDNAPRFYTSLFQESVSENVP 271 NDN P F L++ +V EN P Sbjct: 588 NDNVPTFDRFLYKSTVRENSP 608 Score = 122 bits (295), Expect = 3e-27 Identities = 95/276 (34%), Positives = 134/276 (48%), Gaps = 16/276 (5%) Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 V N G TT L DRE +S YLL V AR+ + T + I+V+D NDN+P F+ Sbjct: 13 VTNGWLGLYTTRSL-DRENISYYLLMVRARNIDEHAQEAITAINITVLDENDNKPRFEAG 71 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 Y ++ E+A +GT + ++ +TDAD G N + Y L G+F +D +G I K Sbjct: 72 AYNVSVYENATIGTVIVRLTSTDADQGRNAHVIYNL-LAGSGIGTFRVDNTTGEITLQKP 130 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDRE + D ++ + P S+ V I I D+N+ PVF ISE S +GT Sbjct: 131 LDREVM---DFFSLFVSVSDPLFSAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGT 187 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 T+ + + D D G NA V Y+I GD F++ +D + LD E + Sbjct: 188 TLLVVTSTDQDIGKNAAVRYAIVDGDPDGYFAV-----NDYGVITLTKSLDSER-NTTFN 241 Query: 765 LVIRA---ASPPLWNDVR--VEILVTDVNDNAPVMK 795 L I A P L R V I V D NDN P+ + Sbjct: 242 LTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFE 277 Score = 37.5 bits (83), Expect = 0.15 Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 6/144 (4%) Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEILVTDVND 789 N+F L + + L T LD E+ Y L++RA + + I V D ND Sbjct: 5 NTFRLASNVTNGWLGLYTTRSLDRENI-SYYLLMVRARNIDEHAQEAITAINITVLDEND 63 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ--YRILSGNNANLILLNETTG 847 N P + + Y++ R+ + DAD Y +L+G+ ++ TTG Sbjct: 64 NKPRFEAGAYNVSVYENATIGTVIVRLTSTDADQGRNAHVIYNLLAGSGIGTFRVDNTTG 123 Query: 848 SMTLSPQLNTNVPKLATMEVSVTD 871 +TL L+ V ++ VSV+D Sbjct: 124 EITLQKPLDREVMDFFSLFVSVSD 147 >SB_41246| Best HMM Match : Cadherin (HMM E-Value=0) Length = 660 Score = 266 bits (651), Expect = 2e-70 Identities = 217/728 (29%), Positives = 331/728 (45%), Gaps = 93/728 (12%) Query: 32 VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91 + EGA + V+ A D+D G+N + Y EL++ +T F Sbjct: 2 ISEGAKANQDVIAAIAIDKDAGENKRLTY--ELISGNTGGD-----------------FT 42 Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 +D +G + T +L+R++ Y + + A D P S+T + + + D NDN P F+ Sbjct: 43 LDPNTGMIKTARNLERQQTFSYNLTIGAADHGLP---SFSATTRVSIVVGDLNDNNPVFN 99 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS--GDV 209 Y+ +V E+ V + + + ATDAD G N+ + Y++ G++ F + S G + Sbjct: 100 PTNYSTTVFENSPVGTS--LLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKSNHGTI 157 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNAPRF----YTSLFQE 264 + LD E Y L I A DGG P SR+ L+ I D NDN P+F YT QE Sbjct: 158 EVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQE 217 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + VP+ + + A D D +A++ Y + D + +I+PR+G + T Sbjct: 218 NSGPGVPVQMTS-SIMATDRDIESHADVRYRLNGSD-----SIQFSINPRTGVITTRAGT 271 Query: 325 DRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 E+ A ++++ D D PR F+P + ++E G Sbjct: 272 GHESLA--EVVIHVLDANDNTPR-------------------FIPSSIQSTISEAASIGQ 310 Query: 384 PVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 V +TA D D + R+ + I G+ G+F I +G ++ V+ LD + + YVL V Sbjct: 311 SVARVTANDPDSGLNGRIFFSINSGS-EGKFEIGRSDG--VVRVSGSLDREAKAVYVLNV 367 Query: 442 SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 SA D R V + + D N+ P F + V E +G+ ++ +ATD D G Sbjct: 368 SAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQG 427 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA ITYS+S F IN TG++T + LDRET Y TV ARDGG Sbjct: 428 SNAAITYSMSYP-----------GFAINSNTGSVTITRPLDRETKQAYSFTVHARDGG-- 474 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 L V + + D NDN P F Y ++++ VGT V V A D DVG NG + Y Sbjct: 475 GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYA 534 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL---------KAVAIDGGTPPQSST 670 + R+ G F ID +G+I NK + R + K A D GT P+++ Sbjct: 535 IRDS-RDPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATN 593 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 V V I I D D PVF + I E+ PIG+++ + G ++ YSI G Sbjct: 594 VTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAG--TIIMYSI--GS 649 Query: 731 DSNSFSLE 738 N FS++ Sbjct: 650 SQNVFSID 657 Score = 260 bits (636), Expect = 2e-68 Identities = 199/655 (30%), Positives = 310/655 (47%), Gaps = 53/655 (8%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 VIA I A D D G N + Y +I GNT F++D +G + + L+ +Q SY L I A Sbjct: 12 VIAAI-AIDKDAGENKRLTYELISGNTGGDFTLDPNTGMIKTARNLERQQTFSYNLTIGA 70 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 D G PS S TT++ I + D+NDN P F + + +V EN P+G S++ V A DAD G N Sbjct: 71 ADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQN 130 Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSA 348 A +TY++T D G + +T G + +G LDRE Y L +TATDGG P R+A Sbjct: 131 AYVTYSVTAGDSHG-LFRAVT-KSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTA 188 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV---TLTATDADEDNR--LHYEI 403 A F +Y + E+ PG PV ++ ATD D ++ + Y + Sbjct: 189 IAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRDIESHADVRYRL 248 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463 G ++ +FSI + G V+T A G A V I++ DAN Sbjct: 249 NGSDSI-QFSINPRTG------------------VITTRA--GTGHESLAEVVIHVLDAN 287 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 + P F + +++ E A IG +V V+A D D G+N +I +S++S + + Sbjct: 288 DNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSG--------SEGK 339 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F I G + + LDRE + Y+L V+A DG V +++ DVNDN P F + Sbjct: 340 FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTK 399 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 + ++ E VG+ + ATD D G N I Y + F I+ +G + + Sbjct: 400 PAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSM-----SYPGFAINSNTGSVTITR 454 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 LDRE+ + A DGG S V V+++I D ND+ P F + + + +P+G Sbjct: 455 PLDRETKQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVG 512 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA-ELVTMVDL---DYESP 759 T + + A D D G N V Y+I+ D F+++ G ++++ + L + S Sbjct: 513 TIVLAVNAEDRDVGNNGHVTYAIRDSRDPGLFTIDANNGLITVNKIISRLQLGQSGFLSN 572 Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 + + A + P +V V I + D D++PV + +D P+G Sbjct: 573 NGSFVFKVEARDHGTSPRATNVTVVINIVDSGDDSPVFNTSSYVVKIDED-RPIG 626 Score = 252 bits (618), Expect = 2e-66 Identities = 194/606 (32%), Positives = 288/606 (47%), Gaps = 72/606 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++PVF Y +V E + GT++L + ATD D G+NA V Y++ D+ Sbjct: 86 IVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSV--TAGDS- 142 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRS--GALLTRASLDREKVARYTVLVKATDQASPVSD 128 +FR +S G + +LDRE Y + + ATD P+S Sbjct: 143 ----------------HGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISR 186 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSA 186 ++ A V I+D NDN P+FS YT S+ E+ S PV + I ATD D+ +++ Sbjct: 187 --TAIAIALVRILDRNDNEPKFSHARYTGSIQEN-SGPGVPVQMTSSIMATDRDIESHAD 243 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +RY + G+ +QFSI+ +G ++ RA G + +++I+ Sbjct: 244 VRYR-LNGSDSIQFSINPRTGVIT----------------TRAGTG----HESLAEVVIH 282 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDN PRF S Q ++SE IG S+ RV A D D G+N + +++ +G+ + Sbjct: 283 VLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN----SGS-E 337 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I G V SG LDRE +A Y L V+A DG PR T F Sbjct: 338 GKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKF 397 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + V+++E G+ +V TATD D+ + + IT + F+I S G +T+ Sbjct: 398 TKPAFNVDVSEGVAVGSVIVNATATDPDQGS--NAAITYSMSYPGFAINSNTGS--VTIT 453 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 +PLD + ++ Y TV A D GG V + I D N+ +P F Y V + P+GT Sbjct: 454 RPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGT 513 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-- 544 VL V+A D DVG N +TY++ + F I+ G IT NK++ R + Sbjct: 514 IVLAVNAEDRDVGNNGHVTYAIRD-------SRDPGLFTIDANNGLITVNKIISRLQLGQ 566 Query: 545 SGYL-------LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 SG+L V ARD G + V I++VD D+ PVF Y I ED +G Sbjct: 567 SGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIG 626 Query: 598 TSVSQV 603 +SV V Sbjct: 627 SSVVMV 632 Score = 248 bits (606), Expect = 7e-65 Identities = 188/600 (31%), Positives = 281/600 (46%), Gaps = 58/600 (9%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 +SE ++ A D D G N LTY + +GN T+DP +G + T+ L+ Sbjct: 2 ISEGAKANQDVIAAIAIDKDAGENKRLTYELI----SGNTGGDFTLDPNTGMIKTARNLE 57 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 R+ Y L + A D G P SAT F P Y + E+ P GT + Sbjct: 58 RQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSL 117 Query: 386 VTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 + +TATDAD + Y +T G++ G F +++ G I VA LD + Y LT++A Sbjct: 118 LDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITA 177 Query: 444 TDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS---ATDSD 497 TD G R+ A+ + I D N+ P F +A YT S+ E++ G V + S ATD D Sbjct: 178 TDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRD 237 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 + +A + Y L+ S QF INP+TG ITT E+++ Sbjct: 238 IESHADVRYRLNGSDSI--------QFSINPRTGVITTRAGTGHESLA------------ 277 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 +V I V+D NDN P F + I E A +G SV++V A D D GLNGRI Sbjct: 278 --------EVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIF 329 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 + ++ EG F I + GV+R + +LDRE+ A + L AIDG P+ V + + Sbjct: 330 FSIN--SGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTL 387 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 +D+ND+ P F +SE +G+ I A DPD+G NA + YS+ F++ Sbjct: 388 QDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSM----SYPGFAI 443 Query: 738 ETRQGSDKAELVTMV-DLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMK 795 + GS VT+ LD E+ ++ Y + A L ++V V + + D NDN+P Sbjct: 444 NSNTGS-----VTITRPLDRET-KQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFP 497 Query: 796 DFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLS 852 Q + D PVG V A D DV + + Y I + L ++ G +T++ Sbjct: 498 TVQ-YQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRDSRDPGLFTIDANNGLITVN 556 Score = 185 bits (451), Expect = 4e-46 Identities = 152/488 (31%), Positives = 227/488 (46%), Gaps = 42/488 (8%) Query: 392 DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GR 449 DA E+ RL YE+ GNT G F++ G +I A+ L+ +Q Y LT+ A D G Sbjct: 21 DAGENKRLTYELISGNTGGDFTLDPNTG--MIKTARNLERQQTFSYNLTIGAADHGLPSF 78 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 S T V I + D N+ PVF Y+ +VFE++P+GT++L V+ATD+D G NA +TYS++ Sbjct: 79 SATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVT 138 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVE 568 + S H + V G I LDRE Y LT+TA DGGVP S + Sbjct: 139 AGDS-----HGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIAL 193 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSV---SQVGATDADVGLNGRIHYELDPKDR 625 + ++D NDNEP F YT +I E++ G V S + ATD D+ + + Y L+ D Sbjct: 194 VRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRDIESHADVRYRLNGSDS 253 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 + F I+P +GVI T ES+A V++H+ D ND+ P Sbjct: 254 IQ--FSINPRTGVITTRAGTGHESLAE------------------VVIHVL--DANDNTP 291 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 F + ISE + IG ++ + A+DPD G N + +SI G + E + Sbjct: 292 RFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGSEGK---FEIGRSDGV 348 Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NY 804 + +D + ++ I + P V + + DVNDN P K + FN + Sbjct: 349 VRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTP--KFTKPAFNVDV 406 Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864 + VG V A D I + +N TGS+T++ L+ + + Sbjct: 407 SEGVAVGSV-IVNATATDPDQGSNAAITYSMSYPGFAINSNTGSVTITRPLDRETKQAYS 465 Query: 865 MEVSVTDG 872 V DG Sbjct: 466 FTVHARDG 473 Score = 140 bits (338), Expect = 2e-32 Identities = 128/404 (31%), Positives = 178/404 (44%), Gaps = 42/404 (10%) Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E A V+ A D D G N ++TY L S + F ++P TG I T + Sbjct: 2 ISEGAKANQDVIAAIAIDKDAGENKRLTYELIS-------GNTGGDFTLDPNTGMIKTAR 54 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 L+R+ Y LT+ A D G+PS S TT V I V D+NDN PVF Y+ + E++ VG Sbjct: 55 NLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVG 114 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSF--VIDPASGVIRTNKALDRESVATHDL 655 TS+ V ATDAD G N + Y + D G F V G I LDRE ++L Sbjct: 115 TSLLDVTATDADSGQNAYVTYSVTAGD-SHGLFRAVTKSNHGTIEVAGNLDREVNDFYNL 173 Query: 656 KAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI---GEIRA 711 A DGG P +++ I ++I D ND+ P F T I ENS G + I A Sbjct: 174 TITATDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMA 233 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 D D +A V Y + G DS FS+ R G + T +ES E+VI Sbjct: 234 TDRDIESHADVRYRL-NGSDSIQFSINPRTG----VITTRAGTGHES---LAEVVIH--- 282 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQ 828 V D NDN P I + + +G RV A D D + ++ Sbjct: 283 ------------VLDANDNTPRFIP-SSIQSTISEAASIGQSVARVTANDPDSGLNGRIF 329 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + I SG+ + + G + +S L+ + + VS DG Sbjct: 330 FSINSGSEGK-FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDG 372 Score = 114 bits (274), Expect = 1e-24 Identities = 94/338 (27%), Positives = 149/338 (44%), Gaps = 15/338 (4%) Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 I E A V A D D G N R+ YEL G F +DP +G+I+T + L+R+ Sbjct: 2 ISEGAKANQDVIAAIAIDKDAGENKRLTYELI-SGNTGGDFTLDPNTGMIKTARNLERQQ 60 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 +++L A D G P S+T V I + D+ND+ PVF + + ENSP+GT++ ++ Sbjct: 61 TFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDV 120 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D G NA V YS+ GD F T+ E+ +D + Y L I A Sbjct: 121 TATDADSGQNAYVTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVND---FYNLTITA 177 Query: 770 AS---PPLWNDVRVEIL-VTDVNDNAPVMKDFQI---IFNNYKDCFPVGPFGRVPAYDAD 822 P + + ++ + D NDN P + I N PV + A D D Sbjct: 178 TDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRD 237 Query: 823 VTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQ 881 + R L+G+++ +N TG +T + T LA + + V D + + Sbjct: 238 IESHADVRYRLNGSDSIQFSINPRTGVIT--TRAGTGHESLAEVVIHVLDANDNTPRFIP 295 Query: 882 LSVR-LITEEMLLNSITVRLNDMTAEQFLSPLLGFFID 918 S++ I+E + R+ + L+ + F I+ Sbjct: 296 SSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN 333 Score = 73.3 bits (172), Expect = 3e-12 Identities = 59/198 (29%), Positives = 95/198 (47%), Gaps = 23/198 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+SP F QY+ V + GT VL + A D+D+G N V Y I D+ Sbjct: 484 VEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIR----DSR 539 Query: 71 NPEDAXXXXXXXXXXVQDVF-RID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 +P V + R+ G+SG L S + V+A D + S Sbjct: 540 DPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGS--------FVFKVEARDHGT--SP 589 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R ++ T+ +NI+D D+ P F+ +Y V +DED + + V+ ++ A + I Sbjct: 590 R-ATNVTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEV----VKKRAGTIIM 644 Query: 189 YAIIGGNTQMQFSIDSLS 206 Y+I G++Q FSID+L+ Sbjct: 645 YSI--GSSQNVFSIDNLT 660 >SB_55456| Best HMM Match : Cadherin (HMM E-Value=0) Length = 736 Score = 242 bits (592), Expect = 3e-63 Identities = 200/657 (30%), Positives = 311/657 (47%), Gaps = 50/657 (7%) Query: 129 RLSSTATIHVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA---TDADVGAN 184 R ST + + I DD NDN P F+E+ Y + E + N V ++ D +V + Sbjct: 51 RNDSTLFLFLGIEDDYNDNAPVFTEQPYMAKIAETPFFSLNSVNGELTLGGPLDFEVARS 110 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL------VIRAQDGGSPSRS 238 + S ++ +V+ + + ++S+ L A + P+ + Sbjct: 111 YMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIASEVPDPNSN 170 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV--RVQAYDADEG-VNAELTYT 295 T +++ + DVNDN P F S++ V E+V + +V ++Q D D+ V + Y Sbjct: 171 TTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYH 230 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXX 354 + D IDP SG +Y + LD E Q + V AT+ + SA A+ Sbjct: 231 LVGADSD-----KFAIDPTSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTL 285 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRF 412 F Y + E+ PGT + +TATDAD L YE+ GG F Sbjct: 286 TLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQA-AYF 344 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVF 469 S+ + NG I+ AQ LD+ R+Y ++ D GG A V + + D N+ P F Sbjct: 345 SVNADNGT--ISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEF 402 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 PYT+ + E+ P GT V V+ATD D G N ++++++S+ + H F IN Sbjct: 403 TGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISA---GDDGGH----FSING- 454 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL-YTA 588 +G +TT + LDRET++ Y LTV+A D GV S + ++V+D NDN P L T Sbjct: 455 SGLVTTARELDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQITDGLTITT 514 Query: 589 NIMEDALVGTSV-SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LD 646 NI E A GT + S + A D D G NG++ Y + D F ++ A+G ++ + A LD Sbjct: 515 NISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR---FTLNSATGRLQISPAGLD 571 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE----SDCLTFYISENSPI 702 RE ++DL D G+PP +++ VH+ I D+ND+ P F+ T+ I+ + Sbjct: 572 RELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGP 631 Query: 703 GT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 GT T+ +I A DPD N V YS+ GD+ F L+ S K + T+ Y Sbjct: 632 GTINKTLIDINATDPDADANGKVAYSL-SGDEHGFFRLDPVTTSAK-QAATITTTQY 686 Score = 235 bits (575), Expect = 4e-61 Identities = 189/640 (29%), Positives = 297/640 (46%), Gaps = 50/640 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND++PVF Q Y A + E T +L + + ++ +++ + + ED Sbjct: 65 DYNDNAPVFTEQPYMAKIAE-----TPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAED 119 Query: 75 AXXXXXXXXXXVQ-DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133 V +V I L L +++ T + A++ P S+ +T Sbjct: 120 LGVPKLESRTTVIIEVTDISDMPPRFLQSFYL--KEIEENTPI--ASEVPDPNSN---TT 172 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRYAII 192 T+ V ++D NDN P F + Y V ED+++ V +++ TD D + Y ++ Sbjct: 173 VTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLV 232 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLLINIRDVN 251 G ++ +F+ID SG + + KTLDYE+ ++ V+ + S S + + + +VN Sbjct: 233 GADSD-KFAIDPTSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLINVN 291 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P F S + ++ E + G I + A DAD G LTY + G ++ Sbjct: 292 DNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTY-----ELRGGQAAYFSV 346 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQ 370 + +G + + LD +T +YQ + DGG A AT F Sbjct: 347 NADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMP 406 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y ++AE+ P GT V +TATD D E+ RL + I+ G+ G FSI NG GL+T A+ Sbjct: 407 YTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSI---NGSGLVTTARE 463 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPIG 485 LD + Y LTVSA D G R + +N+ D N+ P + + T ++ E A G Sbjct: 464 LDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQITDGLTITTNISEGAGGG 523 Query: 486 TTVL-VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRET 543 T +L ++A D D G N Q+TYS+S D +F +N TG + + LDRE Sbjct: 524 TVLLSSIAAVDPDAGSNGQLTYSMSG---------GDSRFTLNSATGRLQISPAGLDREL 574 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF----KQQLYTANIMEDALVGT- 598 Y L + D G P +++T V ++++DVNDN P F Q L T I D GT Sbjct: 575 KDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTI 634 Query: 599 --SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636 ++ + ATD D NG++ Y L E G F +DP + Sbjct: 635 NKTLIDINATDPDADANGKVAYSL--SGDEHGFFRLDPVT 672 Score = 192 bits (467), Expect = 5e-48 Identities = 143/470 (30%), Positives = 237/470 (50%), Gaps = 35/470 (7%) Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP-PGTPVVT-LTATDADE 395 A++ DP + T T F+ Y ++ ED PG V L TD D+ Sbjct: 161 ASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDK 220 Query: 396 D---NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--- 449 + R+ Y + G ++ +F+I +G + + + LD++++ + V AT++ Sbjct: 221 NPVFRRVLYHLVGADS-DKFAIDPTSGT--LYINKTLDYEKQINFTFDVVATETDTSEKF 277 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 S A V + + + N+ P+F + Y ++ E+ GT + ++ATD+D+G +TY Sbjct: 278 SANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTY--- 334 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG--VPSLSDTTDV 567 E+ A+ F +N G I+ ++LD +T+ Y ++ +DGG ++ T V Sbjct: 335 -ELRGGQAAY----FSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIAT-V 388 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 +++ DVNDN+P F YT++I E+ GT V QV ATD D G NGR+ + + D + Sbjct: 389 TVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGD-DG 447 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-V 686 G F I+ SG++ T + LDRE++AT+ L A D G + V + + + D ND+ P + Sbjct: 448 GHFSIN-GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQI 506 Query: 687 FESDCLTFYISENSPIGTTI-GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 + +T ISE + GT + I A DPD G N + YS+ GGD + F+L + G + Sbjct: 507 TDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGD--SRFTLNSATGRLQ 564 Query: 746 AELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792 ++ LD E + Y+L+I SPP N V + + DVNDN P Sbjct: 565 ---ISPAGLDREL-KDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTP 610 Score = 152 bits (369), Expect = 3e-36 Identities = 119/431 (27%), Positives = 193/431 (44%), Gaps = 27/431 (6%) Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV--VSATDSDVG-INAQITYSL 508 T V + + D N+ P F + Y V ED + V+ + TD D + ++ Y L Sbjct: 172 TVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHL 231 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDV 567 V +F I+P +G + NK LD E + V A + S V Sbjct: 232 --------VGADSDKFAIDPTSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASV 283 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 +++++VNDN+P+F + Y + E+ GT ++ + ATDAD+G G + YEL + + Sbjct: 284 TLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYEL--RGGQA 341 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPPV 686 F ++ +G I + LD +++ + V DGG Q + V + ++D+ND+ P Sbjct: 342 AYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPE 401 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 F T I+EN P GT + ++ A D D G N + ++I GDD FS+ GS Sbjct: 402 FTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSI---NGS--G 456 Query: 747 ELVTMVDLDYESPRKKYELVIRAASPPL---WNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 + T +LD E+ Y L + A + DV++ + V D NDN P + D I N Sbjct: 457 LVTTARELDRET-IATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQITDGLTITTN 515 Query: 804 YKDCFPVGP--FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQ-LNTNVP 860 + G + A D D Q + LN TG + +SP L+ + Sbjct: 516 ISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFTLNSATGRLQISPAGLDRELK 575 Query: 861 KLATMEVSVTD 871 + ++VTD Sbjct: 576 DSYDLIINVTD 586 Score = 138 bits (334), Expect = 6e-32 Identities = 109/407 (26%), Positives = 184/407 (45%), Gaps = 43/407 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +++ ND+ P+F Y ++ E + GT + + ATD D+G T +T + Sbjct: 285 LTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLG-------TFGALTYELR 337 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + A F ++ +G + LD + + +Y + D + Sbjct: 338 GGQAA-------------YFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQE-- 382 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + AT+ V + D NDN P+F+ YT + E++ ++ ++ ATD D G N + + Sbjct: 383 IAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPA--GTIVFQVTATDKDSGENGRLSFN 440 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I G+ FSI+ SG V+ + LD E + +Y L + A D G SR QL +N+ D Sbjct: 441 ISAGDDGGHFSING-SGLVTTARELDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDE 499 Query: 251 NDNAPRFYTSL-FQESVSENVPIGYSIV-RVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 NDN P+ L ++SE G ++ + A D D G N +LTY+M+ D Sbjct: 500 NDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR------ 553 Query: 309 ITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 T++ +G + S LDRE + Y L++ TD G PP + + T F Sbjct: 554 FTLNSATGRLQISPAGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFD 613 Query: 368 PGQYE----VELAEDEPPGT---PVVTLTAT--DADEDNRLHYEITG 405 P + + DE PGT ++ + AT DAD + ++ Y ++G Sbjct: 614 PNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSG 660 Score = 126 bits (305), Expect = 2e-28 Identities = 97/328 (29%), Positives = 159/328 (48%), Gaps = 37/328 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ P F Y + + E +GT V + ATD+D G+N + + I Sbjct: 390 VTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISA------ 443 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D F I+G SG + T LDRE +A YT+ V A D VS R Sbjct: 444 -GDDGGH------------FSING-SGLVTTARELDRETIATYTLTVSAYDHG--VSSR- 486 Query: 131 SSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + VN++D+NDN PQ ++ T T ++ E +++ I A D D G+N + Y Sbjct: 487 HKDVQLTVNVLDENDNTPQITDGLTITTNISEGAG-GGTVLLSSIAAVDPDAGSNGQLTY 545 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 ++ GG++ +F+++S +G + + LD E SY L+I D GSP +N+T + + I Sbjct: 546 SMSGGDS--RFTLNSATGRLQISPAGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTIL 603 Query: 249 DVNDNAPRFYTSLFQE------SVSENV-PIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 DVNDN P F + Q +V E I +++ + A D D N ++ Y+++ ++ Sbjct: 604 DVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEH 663 Query: 302 TGNVDL-PITIDPRSGWVYTSGQLDRET 328 G L P+T + T+ Q + T Sbjct: 664 -GFFRLDPVTTSAKQAATITTTQYSKIT 690 Score = 54.8 bits (126), Expect = 9e-07 Identities = 43/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%) Query: 458 NITDANNYAPVFENAPYTASVFEDAPIG-------TTVLVVSATDSDVGINAQITYSLSS 510 N+ +N P V E+A IG +T+ + + D NA + + Sbjct: 19 NVVKGSNNIPYITTTNLALRVNENATIGIQGIRNDSTLFLFLGIEDDYNDNAPVF----T 74 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 E A F +N G +T LD E Y+L V A D GVP L T V I Sbjct: 75 EQPYMAKIAETPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIE 134 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 V D++D P F Q Y I E+ + + V Sbjct: 135 VTDISDMPPRFLQSFYLKEIEENTPIASEV 164 Score = 52.0 bits (119), Expect = 7e-06 Identities = 71/319 (22%), Positives = 131/319 (41%), Gaps = 26/319 (8%) Query: 573 DVNDNEPVFKQQLYTANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELD----PK 623 D NDN PVF +Q Y A I E V ++ G D +V + + + PK Sbjct: 65 DYNDNAPVFTEQPYMAKIAETPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPK 124 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVAT-HDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 + +I+ + L + + +A + P ++TV V + + D+ND Sbjct: 125 LESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIASEVPDPNSNTTVTVVVTVVDVND 184 Query: 683 SPPVFESDCLTFYISENSPI-GTTIG-EIRAHDPDEGP--NAVVHYSIKGGDDSNSFSLE 738 + P F F + E+ + G + +++ D D+ P V+++ + G DS+ F+++ Sbjct: 185 NRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLV--GADSDKFAID 242 Query: 739 TRQGSDKAELVTMVDLDYESP-RKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMK 795 G+ L LDYE +++V S + V + + +VNDN P+ Sbjct: 243 PTSGT----LYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLINVNDNKPMFA 298 Query: 796 DFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSP 853 + ++ P + A DAD+ L Y L G A +N G+++ + Sbjct: 299 KSSYNYTMDEEITPGTHIADITATDADLGTFGALTYE-LRGGQAAYFSVNADNGTISAAQ 357 Query: 854 QLNTNVPKLATMEVSVTDG 872 L+ + + + V DG Sbjct: 358 ILDYDTLRQYQFSLVVKDG 376 >SB_18678| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 727 Score = 240 bits (587), Expect = 1e-62 Identities = 189/605 (31%), Positives = 289/605 (47%), Gaps = 57/605 (9%) Query: 152 EKTYTVS-VDEDISVTDNPVIAKIKATDADVGA-NSAIRYAIIGGNTQMQFSIDSLSGDV 209 E T T+S E T + + ATD D N + YAI+ GN F ID G + Sbjct: 97 EATKTMSCTPETCKSTSGLSVLTMSATDMDAEEINQRVNYAIVSGNEDGIFDIDFNKGVI 156 Query: 210 SLVKTLDYEQVRSYRLVIRAQ-----DGGSPSR--SNTTQLLINIRDVNDNAPRFYTSLF 262 L + LD+EQ+ Y+L I A D P SN T + +N+ D +D RF + Sbjct: 157 RLARELDFEQLTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSY 216 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 S+ EN +G +++V A D D+ +NA +TY + DK+ T + + I +G + +G Sbjct: 217 SASIPENAAMGSVVMQVHAKDLDKSINAPVTYAI-DKE-TNPLRM-FNIANITGEITLNG 273 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LDRET A+Y+L + A + T +P Y + E+ G Sbjct: 274 SLDRETIAEYRLRILAYC--TIYQDHTEVLITVTDVNDNIPLFTLPS-YNTTVNENAAIG 330 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 T V+ + A D D+ + F I +G +I V LD +++ Y +TV Sbjct: 331 TYVIQVQAEDIDQGVNASFIYEIAYASHEFVIGEHSG--IIIVNGTLDREKKDFYSITVI 388 Query: 443 ATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 A + S G + + + D N+ +P+F A Y++ ++E+ P GT V+ VSA DSD+G Sbjct: 389 ARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIG 448 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG--- 556 NA ++Y++ S+ H Q F IN + G ITT++ LDRE ++ + L VTA DG Sbjct: 449 SNAMVSYAVLSDAEG-----HYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPL 503 Query: 557 ----GVPSLSDTTD-------------------VEISVVDVNDNEPVFKQQLYTANIMED 593 G+ L+ T D V ++V+D NDN PV + YT +I E+ Sbjct: 504 STISGLLQLNHTLDREVVSKHSLRVTASDRGGEVTVNVLDSNDNIPVCDKVYYTISIPEN 563 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 VG S+ + TD D G N + Y + FV+D +G++ NK LD E T Sbjct: 564 TSVGQSLIHLNCTDQDSGENAHLLYHM---VSGHSKFVVDNVTGIMSLNKLLDFEEKPTV 620 Query: 654 DLKAV-AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIR 710 A+ ID G PP S V V++ ++++ND+ P F D TF+ISE + +G + Sbjct: 621 FTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVS 680 Query: 711 AHDPD 715 AHD D Sbjct: 681 AHDLD 685 Score = 210 bits (512), Expect = 2e-53 Identities = 193/663 (29%), Positives = 311/663 (46%), Gaps = 97/663 (14%) Query: 36 ASSGTTVLTLKATDQDIGK-NAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG 94 ++SG +VLT+ ATD D + N V Y I V+ + ED +F ID Sbjct: 111 STSGLSVLTMSATDMDAEEINQRVNYAI--VSGN----EDG-------------IFDIDF 151 Query: 95 RSGALLTRASLDREKVARYTVLVKA----TDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 G + LD E++ +Y + + A T+ + LS+ + VN++D +D +F Sbjct: 152 NKGVIRLARELDFEQLTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRF 211 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDV 209 + +Y+ S+ E+ ++ V+ ++ A D D N+ + YAI ++ F+I +++G++ Sbjct: 212 NNYSYSASIPENAAM--GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEI 269 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 +L +LD E + YRL I A + T++LI + DVNDN P F + +V+EN Sbjct: 270 TLNGSLDRETIAEYRLRILAY---CTIYQDHTEVLITVTDVNDNIPLFTLPSYNTTVNEN 326 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 IG +++VQA D D+GVNA Y + Y + I SG + +G LDRE + Sbjct: 327 AAIGTYVIQVQAEDIDQGVNASFIYEIA---YASH---EFVIGEHSGIIIVNGTLDREKK 380 Query: 330 AKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Y + V A + + T F Y + E+EPPGT V+ + Sbjct: 381 DFYSITVIARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQV 440 Query: 389 TATDAD------------EDNRLHYE---ITGGN--------------TRGRFSITSQNG 419 +A D+D D HY+ I N T R +T+ +G Sbjct: 441 SANDSDIGSNAMVSYAVLSDAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDG 500 Query: 420 R------GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473 GL+ + LD + ++ L V+A+D GG V +N+ D+N+ PV + Sbjct: 501 APLSTISGLLQLNHTLDREVVSKHSLRVTASDRGGE-----VTVNVLDSNDNIPVCDKVY 555 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 YT S+ E+ +G +++ ++ TD D G NA + Y + V+ H +FV++ TG + Sbjct: 556 YTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHM--------VSGH-SKFVVDNVTGIM 606 Query: 534 TTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + NKLLD E + + + + D G P LS V ++V +VNDN P F Q YT I E Sbjct: 607 SLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISE 666 Query: 593 ------DALVG-TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 A+VG S + A ++ L G++ Y L G F ID +GV+R +L Sbjct: 667 GDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTL---GNSTGPFAIDKDTGVLRAVGSL 723 Query: 646 DRE 648 DRE Sbjct: 724 DRE 726 Score = 138 bits (333), Expect = 8e-32 Identities = 136/485 (28%), Positives = 235/485 (48%), Gaps = 43/485 (8%) Query: 485 GTTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G +VL +SATD D IN ++ Y++ S NE D F I+ G I + LD E Sbjct: 114 GLSVLTMSATDMDAEEINQRVNYAIVS--GNE-----DGIFDIDFNKGVIRLARELDFEQ 166 Query: 544 MSGYLLTVTA-----RDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 ++ Y L ++A D +P LS+ T V ++V+D +D F Y+A+I E+A + Sbjct: 167 LTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAM 226 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G+ V QV A D D +N + Y +D + F I +G I N +LDRE++A + L+ Sbjct: 227 GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEITLNGSLDRETIAEYRLR 286 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +A T Q T ++ I + D+ND+ P+F ++EN+ IGT + +++A D D+ Sbjct: 287 ILAY--CTIYQDHTEVL-ITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQ 343 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASP 772 G NA Y I S+ F + G ++ LD E + Y + + A S Sbjct: 344 GVNASFIYEIAYA--SHEFVI----GEHSGIIIVNGTLDREK-KDFYSITVIARETETSA 396 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQY 829 ++V + +++ D NDN+P+ Y++ P G F +V A D+D+ + Y Sbjct: 397 GFHSNVTITVMLRDENDNSPIFSRALYSSPIYEN-EPPGTFVIQVSANDSDIGSNAMVSY 455 Query: 830 RILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--VNEIKAMMQLSVR 885 +LS + +N G++T S +L+ + V+ +DG ++ I ++QL+ Sbjct: 456 AVLSDAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTISGLLQLNHT 515 Query: 886 LITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGN 945 L E + +S+ V +D E ++ L D I C K Y S+ ++T V + Sbjct: 516 LDREVVSKHSLRVTASDRGGEVTVNVL-----DSNDNIPVCDKV-YYTISIPENTSVGQS 569 Query: 946 ILNVS 950 +++++ Sbjct: 570 LIHLN 574 Score = 133 bits (321), Expect = 2e-30 Identities = 101/333 (30%), Positives = 165/333 (49%), Gaps = 33/333 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD +D F Y AS+ E A+ G+ V+ + A D D NA V Y I+ T Sbjct: 199 VNVLDADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKSINAPVTYAIDKET---- 254 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP +F I +G + SLDRE +A Y + + A + D Sbjct: 255 NP--------------LRMFNIANITGEITLNGSLDRETIAEYRLRILA--YCTIYQDHT 298 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + + D NDN P F+ +Y +V+E+ ++ + +++A D D G N++ Y Sbjct: 299 E----VLITVTDVNDNIPLFTLPSYNTTVNENAAI--GTYVIQVQAEDIDQGVNASFIYE 352 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIR 248 I +F I SG + + TLD E+ Y + + A++ + + SN T + + +R Sbjct: 353 I--AYASHEFVIGEHSGIIIVNGTLDREKKDFYSITVIARETETSAGFHSNVT-ITVMLR 409 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN+P F +L+ + EN P G +++V A D+D G NA ++Y + D G+ Sbjct: 410 DENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL-SDAEGHYQY- 467 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 I+ ++G + TS +LDRE ++L VTA+DG Sbjct: 468 FKINAKNGTITTSRRLDRENITTFRLRVTASDG 500 Score = 103 bits (248), Expect = 2e-21 Identities = 155/625 (24%), Positives = 257/625 (41%), Gaps = 73/625 (11%) Query: 273 GYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 G S++ + A D D E +N + Y + +GN D ID G + + +LD E + Sbjct: 114 GLSVLTMSATDMDAEEINQRVNYAIV----SGNEDGIFDIDFNKGVIRLARELDFEQLTQ 169 Query: 332 YQLLVTA----TDGGDPPRSATATXXXXXXXXXXXXXX---FMPGQYEVELAEDEPPGTP 384 Y+L ++A T+ P++ + F Y + E+ G+ Sbjct: 170 YKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAMGSV 229 Query: 385 VVTLTATDADEDNR--LHYEITGG-NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 V+ + A D D+ + Y I N F+I + G IT+ LD + Y L + Sbjct: 230 VMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGE--ITLNGSLDRETIAEYRLRI 287 Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 A + + T ++ I +TD N+ P+F Y +V E+A IGT V+ V A D D G+N Sbjct: 288 LAYCTIYQDHTEVL-ITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQGVN 346 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGA------ITTNKLLDRETMSGY----LLTV 551 A Y ++ + H ++N T + ET +G+ +TV Sbjct: 347 ASFIYEIAYASHEFVIGEHSGIIIVNGTLDREKKDFYSITVIARETETSAGFHSNVTITV 406 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT--ANIMEDALVGTSVS-------- 601 RD S + + S + N+ F Q+ ++I +A+V +V Sbjct: 407 MLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLSDAEGHYQ 466 Query: 602 --QVGATDADVGLNGRIHYELDPKDR-----EEGSFVIDPASGVIRTNKALDRESVATHD 654 ++ A + + + R+ E R +G+ + SG+++ N LDRE V+ H Sbjct: 467 YFKINAKNGTITTSRRLDRENITTFRLRVTASDGA-PLSTISGLLQLNHTLDREVVSKHS 525 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L+ A D G V + + D ND+ PV + T I EN+ +G ++ + D Sbjct: 526 LRVTASDRGGE-------VTVNVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQ 578 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL---VIRAAS 771 D G NA + Y + G + F ++ G + LD+E + + VI Sbjct: 579 DSGENAHLLYHMVSG--HSKFVVDNVTGIMSLNKL----LDFEEKPTVFTVAIEVIDHGR 632 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV--GPFGRVPAYDAD------- 822 PPL V V + V +VNDN P F + F V G V A+D D Sbjct: 633 PPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCP 692 Query: 823 VTDKLQYRILSGNNANLILLNETTG 847 + KLQY + GN+ +++ TG Sbjct: 693 LCGKLQYTL--GNSTGPFAIDKDTG 715 Score = 79.0 bits (186), Expect = 5e-14 Identities = 61/214 (28%), Positives = 99/214 (46%), Gaps = 32/214 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND+ PV + Y S+ E S G +++ L TDQD G+NA + Y +V+ Sbjct: 539 VNVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLY--HMVSG--- 593 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129 F +D +G + LD EK +TV ++ D P Sbjct: 594 ----------------HSKFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRP---P 634 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA--- 186 LS ++V + + NDNYP F + YT + E D+ ++ + A D D +++ Sbjct: 635 LSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLC 694 Query: 187 --IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 ++Y + GN+ F+ID +G + V +LD E Sbjct: 695 GKLQYTL--GNSTGPFAIDKDTGVLRAVGSLDRE 726 >SB_22450| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2806 Score = 238 bits (583), Expect = 4e-62 Identities = 189/611 (30%), Positives = 297/611 (48%), Gaps = 45/611 (7%) Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSG------DVSLVKTLDYEQVRSYRLVIRAQDGGS 234 V + + + + II GN Q FS+DS D+ K L+ E V SY L + QD + Sbjct: 1234 VYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRT 1293 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + T++ I + D NDN P F + +++ E++P+ SI R++A DAD G N + Y Sbjct: 1294 KRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYY 1353 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 + +K + I+P SG V + +L + ++L V A D PP ++ Sbjct: 1354 SFKEKTTS------FAINPISGVVSVAQKLSNSARI-HRLTVVARDRALPPSKPKSSRNC 1406 Query: 355 XXXXXXXXXXXFMPG---QYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNT 408 F P + +++ + G TL D D+ + EIT GN Sbjct: 1407 QLIVNVQAVNQFSPEFSVKTQLQNVSEGTSGIVYATLGIIDKDKGSNGDIDRVEITSGNL 1466 Query: 409 RGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465 G FSI S + V +PLD + Y +T++A D G R+ + ++++N+ D N+ Sbjct: 1467 DGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDN 1526 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P F + Y ++ E API T VL V ATD D G N I Y ++ NE +F Sbjct: 1527 NPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITR--GNEL-----GKFE 1579 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS---DTTDVEISVVDVNDNEPVFK 582 IN +TG I T LD E+ + LTV A D GVP S T V ++++D ND++P FK Sbjct: 1580 INSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSRKISTVPVVVNILDANDHDPEFK 1638 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Y ++ ED GTSV V A D D G NG++ Y L + F I+P +G+IRT Sbjct: 1639 APEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSL--ANLRPVPFEIEPDTGIIRTT 1696 Query: 643 KALDRESVATH--DLKAVAIDGGTPPQSST-VIVHIKIEDINDSPPVFESDCLTFYISEN 699 LDR++ +L+ A D GTP + T +V ++++++ND+ PV + + N Sbjct: 1697 TNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILVDRN 1756 Query: 700 SPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 +P+G I + A D D + + Y G+ +FSL+ + G EL T L Sbjct: 1757 APVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTG----ELRTARSL--RG 1810 Query: 759 PRKKYELVIRA 769 ++++ L+I+A Sbjct: 1811 LQREFTLIIKA 1821 Score = 225 bits (550), Expect = 4e-58 Identities = 195/616 (31%), Positives = 290/616 (47%), Gaps = 50/616 (8%) Query: 87 QDVFRIDGRSGA------LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140 Q +F +D R + + T L+RE VA Y + V D+ + R +++ + Sbjct: 1250 QGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRTK---RTLDRTKVNITV 1306 Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200 D NDN P F +K Y ++ EDI + + IA+I+A DADVG N I Y+ T F Sbjct: 1307 DDSNDNRPIFLKKKYLKTIPEDIPM--HTSIARIEAVDADVGPNGLIYYSFKEKTT--SF 1362 Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAPR 256 +I+ +SG VS+ + L R +RL + A+D P S QL++N++ VN +P Sbjct: 1363 AINPISGVVSVAQKLS-NSARIHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPE 1421 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--LPITIDPR 314 F ++VSE G + D D+G N ++ + +GN+D I P Sbjct: 1422 FSVKTQLQNVSEGTS-GIVYATLGIIDKDKGSNGDIDRV---EITSGNLDGAFSIKSSPN 1477 Query: 315 SGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 V LDRE Y + +TA D G P R+ + F +Y Sbjct: 1478 DYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYIT 1537 Query: 374 ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 L+E P TPV+ + ATD D + + Y IT GN G+F I S+ G+ I LD+ Sbjct: 1538 NLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGKFEINSKTGQ--IYTKGDLDY 1595 Query: 432 KQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + +R+ LTV+A D + T V +NI DAN++ P F+ Y ++ED GT+ Sbjct: 1596 ESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTS 1655 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSG 546 V VSA D D G N ++ YSL++ F I P TG I T LDR+T + Sbjct: 1656 VFTVSAEDLDSGGNGKVRYSLAN--------LRPVPFEIEPDTGIIRTTTNLDRDTGLPE 1707 Query: 547 YL-LTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQ 602 ++ L V A D G P +T T V++ V ++NDN PV KQ + NI+ D A VG ++ Sbjct: 1708 FINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQ--FKCNILVDRNAPVGVLITT 1765 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+ + +F +DP +G +RT ++L R L A DG Sbjct: 1766 VTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 1824 Query: 663 -GTPPQSSTVIVHIKI 677 P + VI+ I I Sbjct: 1825 IQESPDTHPVILKISI 1840 Score = 215 bits (524), Expect = 6e-55 Identities = 220/832 (26%), Positives = 366/832 (43%), Gaps = 115/832 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV N SP F ++ +V EG +SG TL D+D G N +++ +E+ + Sbjct: 1410 VNVQAVNQFSPEFSVKTQLQNVSEG-TSGIVYATLGIIDKDKGSNGDID-RVEITSG--- 1464 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDR 129 N + A V + LDRE Y V + A D+ +PV + Sbjct: 1465 NLDGAFSIKSSPNDYAVQVIK------------PLDRELAPFGYNVTLTAYDKGTPVRN- 1511 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + VN++D+NDN P+F++ Y ++ E ++ PV+ ++ ATD D G+N I Y Sbjct: 1512 --GSYVLRVNVLDENDNNPEFNQSRYITNLSE-LAPIHTPVL-RVLATDKDAGSNGNIMY 1567 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRS-NTTQLLINI 247 I GN +F I+S +G + LDYE + + L + A DG SR +T +++NI Sbjct: 1568 VITRGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNI 1627 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D ND+ P F +++ + E++ G S+ V A D D G N ++ Y++ + + Sbjct: 1628 LDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLR-----PV 1682 Query: 308 PITIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 P I+P +G + T+ LDR+T L V A+D G P R T T Sbjct: 1683 PFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAP 1742 Query: 366 FMPGQYEVELAEDE--PPGTPVVTLTATD---ADEDNRLHYEITGGNTRGRFSITSQNGR 420 + Q++ + D P G + T+TA D +D+D L Y+ T GNT FS+ + G Sbjct: 1743 VLK-QFKCNILVDRNAPVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGE 1801 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQINITDANN-YAPVFENAPYTASV 478 + A+ L Q R + L + ATD S DT V + I+ A +N T V Sbjct: 1802 --LRTARSLRGLQ-REFTLIIKATDGIQESPDTHPVILKISIVGGRQARKLQNHVSTKCV 1858 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 D+P+ L + + ++ ++++ N HH Sbjct: 1859 --DSPLYAKALKIKQEQKSYSSLQPLIFA-TAKLHNR---HHP----------------- 1895 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 + RET+S Y L ++A D G S T + + + DVND PVF + +Y + E+ VG Sbjct: 1896 VFRETISSYTLNISAVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYEVTLPENITVGQ 1955 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 +V+ H KD+E+ + I+ + + ++D + V Sbjct: 1956 TVT---------------HVHASDKDQEQEMYKIE----IQAMDSSVDNQKVG------- 1989 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 ST ++ + + DIND+ P+ + + E+ + + I A DPD GP Sbjct: 1990 ----------STHVI-VTLLDINDNSPIVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGP 2038 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 + +S+ + + F+++++ G + LD+E + Y L +R SP L+ Sbjct: 2039 GGEIEFSLP--ESTRKFNIDSKSGVIRLR----QRLDFEQ-KSTYNLTVRVTDKGSPALF 2091 Query: 776 NDVRVEILVTDVNDN--APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825 DV V + V DVN+N APV N++ D P P + D D Sbjct: 2092 TDVEVVVNVLDVNENSLAPVFSGALEYPNSFDDIKSFSPTDFGPLENKDHED 2143 Score = 210 bits (512), Expect = 2e-53 Identities = 208/797 (26%), Positives = 343/797 (43%), Gaps = 81/797 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P+F ++Y ++ E T++ ++A D D+G N + Y+ + T Sbjct: 1304 ITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS-- 1361 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSDR 129 F I+ SG + L ++ R TV+ A D+A P S Sbjct: 1362 -------------------FAINPISGVVSVAQKLSNSARIHRLTVV--ARDRALPPSKP 1400 Query: 130 LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI- 187 SS + VN+ N P+FS KT +V E T V A + D D G+N I Sbjct: 1401 KSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEG---TSGIVYATLGIIDKDKGSNGDID 1457 Query: 188 RYAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLL 244 R I GN FSI S D V ++K LD E Y + + A D G+P R+ + L Sbjct: 1458 RVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLR 1517 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 +N+ D NDN P F S + ++SE PI ++RV A D D G N + Y +T + G Sbjct: 1518 VNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGK 1577 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXX 362 + I+ ++G +YT G LD E++ ++ L V A DG + +T Sbjct: 1578 FE----INSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDH 1633 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRG 421 F +Y +L ED PGT V T++A D D + N R F I G Sbjct: 1634 DPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLRPVPFEIEPDTGII 1693 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478 T D L V A+D G R +V++ + + N+ APV + V Sbjct: 1694 RTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILV 1753 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 +AP+G + V+A D D+ Q + S N A F ++P+TG + T + Sbjct: 1754 DRNAPVGVLITTVTAIDIDISDKDQ-SLMYKSTFGNTGKA-----FSLDPKTGELRTARS 1807 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 L R + L + A D G+ DT V + + V + Q + ++ L Sbjct: 1808 L-RGLQREFTLIIKATD-GIQESPDTHPVILKISIVGGRQARKLQNHVSTKCVDSPLYAK 1865 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 ++ + + + L P +I + + + + RE+++++ L Sbjct: 1866 ALK--------IKQEQKSYSSLQP--------LIFATAKLHNRHHPVFRETISSYTLNIS 1909 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A+D G +S+ I+++KI D+ND PVF+ + EN +G T+ + A D D+ Sbjct: 1910 AVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYEVTLPENITVGQTVTHVHASDKDQ-E 1968 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP---RKKYELVIRAASPPLW 775 + I+ D S++ ++ +VT++D++ SP KK+ + ++ Sbjct: 1969 QEMYKIEIQAMDS----SVDNQKVGSTHVIVTLLDINDNSPIVKPKKFNVTVQ------- 2017 Query: 776 NDVRVEILVTDVNDNAP 792 D+ V +VT ++ + P Sbjct: 2018 EDLLVNAVVTSIHASDP 2034 Score = 177 bits (431), Expect = 1e-43 Identities = 174/581 (29%), Positives = 260/581 (44%), Gaps = 44/581 (7%) Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + TS +L+RE+ A Y+L V D F+ +Y + E Sbjct: 1268 IKTSKRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPE 1327 Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 D P T + + A DAD + ++Y T F+I +G +++VAQ L R Sbjct: 1328 DIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS--FAINPISG--VVSVAQKLS-NSAR 1382 Query: 436 RYVLTVSATDSG------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + LTV A D S + +N+ N ++P F +V E G Sbjct: 1383 IHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEGTS-GIVYA 1441 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI--NPQTGAITTNKLLDRETMS-G 546 + D D G N I EI++ + D F I +P A+ K LDRE G Sbjct: 1442 TLGIIDKDKGSNGDID---RVEITS---GNLDGAFSIKSSPNDYAVQVIKPLDRELAPFG 1495 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y +T+TA D G P + + + ++V+D NDN P F Q Y N+ E A + T V +V AT Sbjct: 1496 YNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLAT 1555 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G NG I Y + + E G F I+ +G I T LD ES DL A+DG P Sbjct: 1556 DKDAGSNGNIMYVIT-RGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDG-VPL 1613 Query: 667 QS---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 QS STV V + I D ND P F++ + E+ GT++ + A D D G N V Sbjct: 1614 QSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVR 1673 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRAAS--PPLWNDVR- 779 YS+ +N + D + T +LD ++ ++ L +RA+ PL + Sbjct: 1674 YSL-----ANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETET 1728 Query: 780 -VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK---LQYRILSG 834 V++ V ++NDNAPV+K F+ ++ PVG V A D D++DK L Y+ G Sbjct: 1729 LVKMRVKEMNDNAPVLKQFKCNILVDRNA-PVGVLITTVTAIDIDISDKDQSLMYKSTFG 1787 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 N L+ TG + + L + + T+ + TDG+ E Sbjct: 1788 NTGKAFSLDPKTGELRTARSLR-GLQREFTLIIKATDGIQE 1827 Score = 161 bits (392), Expect = 6e-39 Identities = 145/545 (26%), Positives = 241/545 (44%), Gaps = 39/545 (7%) Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL----IT 424 G Y + E P GTPV N + + I GN +G FS+ S+ I Sbjct: 1210 GIYSAFIPEITPIGTPVKCDLKMGVYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIK 1269 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDA 482 ++ L+ + Y L V D + D V I + D+N+ P+F Y ++ ED Sbjct: 1270 TSKRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDI 1329 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+ T++ + A D+DVG N I YS + ++ F INP +G ++ + L Sbjct: 1330 PMHTSIARIEAVDADVGPNGLIYYSFKEKTTS---------FAINPISGVVSVAQKLSNS 1380 Query: 543 TMSGYLLTVTARDGGV----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 + LTV ARD + P S + ++V VN P F + N+ E G Sbjct: 1381 ARI-HRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSE-GTSGI 1438 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVI--DPASGVIRTNKALDRE-SVATHDL 655 + +G D D G NG I +G+F I P ++ K LDRE + +++ Sbjct: 1439 VYATLGIIDKDKGSNGDIDRVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNV 1498 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D GTP ++ + ++ + + D ND+ P F +SE +PI T + + A D D Sbjct: 1499 TLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKD 1558 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPL 774 G N + Y I G++ F + ++ G ++ T DLDYES R++++L + A PL Sbjct: 1559 AGSNGNIMYVITRGNELGKFEINSKTG----QIYTKGDLDYES-RQRFDLTVAALDGVPL 1613 Query: 775 W----NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQ 828 + V V + + D ND+ P K + + Y+D P V A D D K++ Sbjct: 1614 QSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVR 1673 Query: 829 YRILSGNNANLILLNETTGSMTLSPQL--NTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 Y L+ + TG + + L +T +P+ ++V +D ++ + V++ Sbjct: 1674 YS-LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKM 1732 Query: 887 ITEEM 891 +EM Sbjct: 1733 RVKEM 1737 Score = 134 bits (325), Expect = 7e-31 Identities = 100/335 (29%), Positives = 158/335 (47%), Gaps = 30/335 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NVLD ND++P F +Y ++ E A T VL + ATD+D G N + Y I + Sbjct: 1517 RVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVI--TRGNE 1574 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L F I+ ++G + T+ LD E R+ + V A D P+ R Sbjct: 1575 LGK-----------------FEINSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSR 1616 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST + VNI+D ND+ P+F Y + ED+ T + + A D D G N +RY Sbjct: 1617 KISTVPVVVNILDANDHDPEFKAPEYRKDLYEDL--TPGTSVFTVSAEDLDSGGNGKVRY 1674 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQDGGSPSRSNTTQLL-IN 246 + + + F I+ +G + LD + L +RA D G+P R T L+ + Sbjct: 1675 S-LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMR 1733 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 ++++NDNAP V N P+G I V A D D ++ ++ K GN Sbjct: 1734 VKEMNDNAPVLKQFKCNILVDRNAPVGVLITTVTAIDID---ISDKDQSLMYKSTFGNTG 1790 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 ++DP++G + T+ L R Q ++ L++ ATDG Sbjct: 1791 KAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 1824 Score = 94.3 bits (224), Expect = 1e-18 Identities = 76/270 (28%), Positives = 135/270 (50%), Gaps = 16/270 (5%) Query: 44 TLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA 103 TL + D GK+ + YTI V +N + + + G++ + + Sbjct: 1905 TLNISAVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYEVTLPENITV-GQTVTHVHAS 1963 Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 D+E+ Y + ++A D +S + ++ ST I V ++D NDN P K + V+V ED+ Sbjct: 1964 DKDQEQ-EMYKIEIQAMD-SSVDNQKVGSTHVI-VTLLDINDNSPIVKPKKFNVTVQEDL 2020 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 V N V+ I A+D D G I +++ + +F+IDS SG + L + LD+EQ +Y Sbjct: 2021 LV--NAVVTSIHASDPDSGPGGEIEFSL--PESTRKFNIDSKSGVIRLRQRLDFEQKSTY 2076 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDN--APRFYTSLFQESVSENV----PIGYSIV 277 L +R D GSP+ ++++N+ DVN+N AP F +L + +++ P + + Sbjct: 2077 NLTVRVTDKGSPALFTDVEVVVNVLDVNENSLAPVFSGALEYPNSFDDIKSFSPTDFGPL 2136 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 + ++ D+ + EL + + D G VDL Sbjct: 2137 ENKDHE-DDHLRLEL-WGLRDAVENGQVDL 2164 Score = 60.1 bits (139), Expect = 3e-08 Identities = 39/139 (28%), Positives = 68/139 (48%), Gaps = 24/139 (17%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + +LD ND+SP+ + +++ +V+E V ++ A+D D G E+E+++ Sbjct: 1992 HVIVTLLDINDNSPIVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSL----- 2046 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 PE F ID +SG + R LD E+ + Y + V+ TD+ SP Sbjct: 2047 ----PESTRK------------FNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPA- 2089 Query: 128 DRLSSTATIHVNIIDDNDN 146 L + + VN++D N+N Sbjct: 2090 --LFTDVEVVVNVLDVNEN 2106 >SB_9507| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2735 Score = 238 bits (583), Expect = 4e-62 Identities = 223/811 (27%), Positives = 361/811 (44%), Gaps = 81/811 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ P+F Y+ VRE G + A D D G NA V Y+I Sbjct: 6 KIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSI------- 58 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +N ED+ ++F I +G L ++LDRE ++R+ + ++A D P R Sbjct: 59 INFEDSRS---------DNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVP---R 106 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S A I + + D ND+ P+FS ++ V + ++ + + + +A D D G N +RY Sbjct: 107 MSGLAQIVIIVDDVNDHAPRFSSGSFHVEI--PLNTPPDSRVFQARALDPDGGHNGLVRY 164 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +II GN Q FSI+ + G + L + L + + I+A+D G P RS+T + I I Sbjct: 165 SIIQGNKQGYFSINHIDGSLFLDEKL--TTLEPIDIKIQARDMGQPERSSTADIRIFIH- 221 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 V P+F +S F +V+EN P G +V + A D + Y++ + GN Sbjct: 222 VQAGPPQFLSSPFVGNVTENEPKGAFVVHISAASLD-----PVMYSIVSGNEAGN----F 272 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMP 368 + P GW+ T LD E Q++Y+++V A D + Sbjct: 273 RLHPGVGWLTTVRPLDNEKQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRN 332 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 G E + +D G+ V+ + A DAD + L Y I R FS+ N G++T + Sbjct: 333 GIIEGNVLKDVAVGSRVMVIDAVDADRSDILSYRIEDEKARRYFSV---NNEGVVTSTRV 389 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 L + Y+ VS +D+G A + Y P + S+ E A +GT V Sbjct: 390 LR-DLDSPYLFKVSVSDNGKPPMVAQAMARVV-LLKYQP--QQDQQRTSIQESAALGTRV 445 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + T + NA+ YS+ S + + +F ++P +G + LD ET+ + Sbjct: 446 FTL-LTAKPIR-NAR--YSIVSPL--------ETKFRVDPYSGDVRVRSGLDYETVKTHR 493 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ----LYTANIMEDALVGTSVSQVG 604 T AR+ + DV I+V D NDN P F LY A + + + T V + Sbjct: 494 FTAEARNTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLE 553 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D LNG + Y L F ++ +G I T D + ++L A D G Sbjct: 554 ATDPDSDLNGIVRYRLITNPGSH--FALNAVTGSITTRGRSDL-FLPWYNLTVEAFDLGK 610 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P + +V+++ PP+F FY+ EN+P G TIG + D +++ Y Sbjct: 611 PSLVTRAVVNVR---TGQFPPLFSRKEYAFYVDENTPRGYTIGTV---DAKSFSGSLLEY 664 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP------PLWNDV 778 + G F L++ G L LD+E Y + + A PL ++ Sbjct: 665 MVIEGSGHKRFVLDSVTG----RLTLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEA 720 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 V+I++ D+NDN P + F++ +Y+D P Sbjct: 721 DVKIVLRDLNDNPP--EFFEL---SYRDTLP 746 Score = 223 bits (544), Expect = 2e-57 Identities = 187/600 (31%), Positives = 284/600 (47%), Gaps = 68/600 (11%) Query: 11 INVLDCNDHSPVFEMQQ----YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I V D ND+ P F M + Y A V + T V TL+ATD D N V Y L+T Sbjct: 514 ITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRY--RLIT 571 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 NP F ++ +G++ TR D + Y + V+A D P Sbjct: 572 ----NPGSH--------------FALNAVTGSITTRGRSDLF-LPWYNLTVEAFDLGKP- 611 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L + A ++V P FS K Y VDE+ P I DA + S Sbjct: 612 --SLVTRAVVNVRT---GQFPPLFSRKEYAFYVDEN-----TPRGYTIGTVDAKSFSGSL 661 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGS----PSRSNTT 241 + Y +I G+ +F +DS++G ++L + LD+E+ + Y + + A++ + P +S Sbjct: 662 LEYMVIEGSGHKRFVLDSVTGRLTLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSE-A 720 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + I +RD+NDN P F+ +++++ E+ P+G +++ V A D D GVN + Y + + + Sbjct: 721 DVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQFF 780 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 ++DP +GW+ T LD ET + LV A D G+P R+ TA Sbjct: 781 --------SVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVND 832 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-R 420 F Y V +AED V T+ ATD D D + Y I G+ F I ++ G Sbjct: 833 NAPRFSQSLYNVFVAEDAGSDQLVATVQATDKDND-PVTYSIASGDNTTNFVINNKTGVI 891 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN-APYTASVF 479 L++ +P Y + +SA+D G AMV + I D NN+ PVF + A Y V Sbjct: 892 KLVSNRKPELIGP--YYTMNISASD-GLHVSQAMVIVAIQDVNNHKPVFTDCASYHPVVM 948 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED P T V+ V A D D G N ++ YS+ E A+++ F I+ +TG +TT + Sbjct: 949 EDDPPNTFVMQVHADDQDTGANGEVIYSI--EKPPGALSY----FAIDDKTGIVTTLQSF 1002 Query: 540 DRETMSGYLLTVTARDGGVPS------LSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 DRE Y + + RDGG+ S L V+I + D ND++PVF+ + Y A I ED Sbjct: 1003 DREEKPVYQIRIIGRDGGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKED 1062 Score = 210 bits (514), Expect = 9e-54 Identities = 183/632 (28%), Positives = 294/632 (46%), Gaps = 56/632 (8%) Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 RY+I+ + +F +D SGDV + LDYE V+++R A++ + ++I + Sbjct: 458 RYSIVSP-LETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYANIDVIITV 516 Query: 248 RDVNDNAPRFYTS----LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 D NDN PRF + L+ VS N + ++A D D +N + Y + Sbjct: 517 EDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT----- 571 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 N ++ +G + T G+ D Y L V A D G P + T Sbjct: 572 NPGSHFALNAVTGSITTRGRSDLFLPW-YNLTVEAFDLGKP---SLVTRAVVNVRTGQFP 627 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F +Y + E+ P G + T+ A + L Y + G+ RF + S GR + Sbjct: 628 PLFSRKEYAFYVDENTPRGYTIGTVDAKSFS-GSLLEYMVIEGSGHKRFVLDSVTGR--L 684 Query: 424 TVAQPLDFKQERR-YVLTVSATDSGGR-----SDTAMVQINITDANNYAPVFENAPYTAS 477 T+ +PLDF+++ Y++TVSA ++ A V+I + D N+ P F Y + Sbjct: 685 TLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEADVKIVLRDLNDNPPEFFELSYRDT 744 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E AP+GTTVL V+A D D G+N Q Y + S+ F ++P TG ITT + Sbjct: 745 LPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQF-----------FSVDPYTGWITTKR 793 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD ET + V A+D G P+ + T V + + +VNDN P F Q LY + EDA Sbjct: 794 PLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVAEDAGSD 853 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V+ V ATD D N + Y + D +FVI+ +GVI+ E + + Sbjct: 854 QLVATVQATDKD---NDPVTYSIASGDNTT-NFVINNKTGVIKLVSNRKPELIGPYYTMN 909 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPD 715 ++ G + VIV I+D+N+ PVF +DC +++ + E+ P T + ++ A D D Sbjct: 910 ISASDGLHVSQAMVIV--AIQDVNNHKPVF-TDCASYHPVVMEDDPPNTFVMQVHADDQD 966 Query: 716 EGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLD-YESPRKKYELVIR----- 768 G N V YSI+ + S F+++ + G + T+ D E P + ++ R Sbjct: 967 TGANGEVIYSIEKPPGALSYFAIDDKTGI----VTTLQSFDREEKPVYQIRIIGRDGGLG 1022 Query: 769 --AASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 + L +V+I + D ND+ PV ++ Q Sbjct: 1023 SSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQ 1054 Score = 208 bits (507), Expect = 6e-53 Identities = 180/618 (29%), Positives = 282/618 (45%), Gaps = 47/618 (7%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-- 193 + + + D NDN P F++ Y V V E++ VI + A D D GAN+ + Y+II Sbjct: 5 LKIQLGDVNDNPPLFAQPVYKVFVRENLQ--GGHVIGQFAARDPDKGANARVTYSIINFE 62 Query: 194 -GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 + FSI +G ++ + TLD E + + L I+A+D G P S Q++I + DVND Sbjct: 63 DSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVND 122 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 +APRF + F + N P + + +A D D G N + Y++ GN +I+ Sbjct: 123 HAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQ----GNKQGYFSIN 178 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 G ++ +L T + + A D G P RS+TA F+ + Sbjct: 179 HIDGSLFLDEKL--TTLEPIDIKIQARDMGQPERSSTA-DIRIFIHVQAGPPQFLSSPFV 235 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 + E+EP G VV ++A D + Y I GN G F + G G +T +PLD + Sbjct: 236 GNVTENEPKGAFVVHISAASLDP---VMYSIVSGNEAGNFRL--HPGVGWLTTVRPLDNE 290 Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF---ENAPYTASVFEDAPIGTTVL 489 ++ RY + V A D R V +N+ + N+ P F N +V +D +G+ V+ Sbjct: 291 KQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVM 350 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V+ A D+D + I LS I +E + F +N + G +T+ ++L R+ S YL Sbjct: 351 VIDAVDAD---RSDI---LSYRIEDEKARRY---FSVNNE-GVVTSTRVL-RDLDSPYLF 399 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 V+ D G P + + ++ +P QQ +I E A +GT V + A Sbjct: 400 KVSVSDNGKPPMVAQAMARVVLLKY---QPQQDQQ--RTSIQESAALGTRVFTL--LTAK 452 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 N R + + P E F +DP SG +R LD E+V TH A A + + Sbjct: 453 PIRNAR-YSIVSPL---ETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYA 508 Query: 670 TVIVHIKIEDINDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + V I +ED ND+ P F + Y+S N T + + A DPD N +V Y Sbjct: 509 NIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYR 568 Query: 726 IKGGDDSNSFSLETRQGS 743 + S+ F+L GS Sbjct: 569 LITNPGSH-FALNAVTGS 585 Score = 180 bits (439), Expect = 1e-44 Identities = 163/589 (27%), Positives = 263/589 (44%), Gaps = 52/589 (8%) Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 INA++ YSL E A ++ F I+ TG I LD ET Y L V RD GVP Sbjct: 1189 INAKLKYSLEYE------AKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVP 1242 Query: 560 -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 S SDT + + V+D ND P F+ Y+A + ED +G + +V A D D G+ Y Sbjct: 1243 LSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRVRAFDEDTGIYKIFKY 1302 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 + D +G F I+P +G + NK+LDRE + H L A + P V +++ Sbjct: 1303 SIAGGD-PQGQFKINPDTGDLYINKSLDREKNSNHILTIRATNIAPPYWYGEASVGVQVL 1361 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP--NAVVHYSIKGGDDSNSFS 736 D+ND+ P F+ + ++ EN+P I ++ DPD P + I+ G++ N F Sbjct: 1362 DVNDNGPQFKPEVYNVFVPENTPPPYVIEKLEVTDPDSDPQNGGPFKFGIRSGNEKNLFE 1421 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVI----RAASP--PLWNDVRVEILVTDVNDN 790 L ++ L T V + E KYELV+ A P P+ + V + V D NDN Sbjct: 1422 L-----TEDGVLKTRVTFNREE-TAKYELVVWAEDNAKHPEKPIKSFASVFVHVRDRNDN 1475 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850 +++ N + F G G+V D D D+ Y ++ + ++ +G++ Sbjct: 1476 QHEAGYLELVLNVLEGKFGGGIIGKVFVKDIDTDDERLYELID-RESEAFSVDRLSGAVI 1534 Query: 851 LSPQLNTNVPK-LATMEVSVTDGVNEIKAMMQLSVRLITEEMLL----NSITVRLNDMTA 905 P N P +M V V+D + + + +V++I +++ L S +RL ++ Sbjct: 1535 SKP----NPPSGEFSMRVKVSDRDSGFQPRVS-TVKIIVKKLPLAAVGKSTAIRLRGISR 1589 Query: 906 EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGD 965 E F++ + F + LA I+ EN+ +FSVQ +T +++V F+A Sbjct: 1590 ETFVAGYITSFKESLAEILRTTSENVDLFSVQ-TAALTSQVIDVRFAAH----------- 1637 Query: 966 PSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGF 1025 SP+YSP + + R L + A ++ + CV EPC C LK Sbjct: 1638 GSPYYSPEKMIALIKAMRKNLEK-AAYKLDSIGVDPCVLEPC-EHSSCHAQLKVPGTVDV 1695 Query: 1026 VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR 1074 + + F I C G E+ ++ C+ +G CR Sbjct: 1696 IGTGEQSFTSI--KADLVAVCDACHAGRRIESRCSEDFCK---NGGTCR 1739 Score = 157 bits (381), Expect = 1e-37 Identities = 168/629 (26%), Positives = 284/629 (45%), Gaps = 65/629 (10%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 +L I + DVNDN P F +++ V EN+ G+ I + A D D+G NA +TY++ + + Sbjct: 4 ELKIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFED 63 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + + +L +I P +G + LDRE +++ L + A D G P S A Sbjct: 64 SRSDNL-FSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVND 122 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F G + VE+ + PP + V A D D + + Y I GN +G FSI +G Sbjct: 123 HAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDG 182 Query: 420 R----GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473 +T +P+D K + A D G RS TA ++I I P F ++P Sbjct: 183 SLFLDEKLTTLEPIDIK--------IQARDMGQPERSSTADIRIFI-HVQAGPPQFLSSP 233 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + +V E+ P G V+ +SA D + YS+ S NEA F ++P G + Sbjct: 234 FVGNVTENEPKGAFVVHISAASLD-----PVMYSIVS--GNEA-----GNFRLHPGVGWL 281 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANI 590 TT + LD E S Y + V A D + + +V ++V++VNDN+P F + + N+ Sbjct: 282 TTVRPLDNEKQSRYKIIVMAMD--LKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNV 339 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 ++D VG+ V + A DAD + + Y ++ D + + GV+ + + L R+ Sbjct: 340 LKDVAVGSRVMVIDAVDAD--RSDILSYRIE--DEKARRYFSVNNEGVVTSTRVL-RDLD 394 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + + K D G PP + + + + + P + D I E++ +GT + + Sbjct: 395 SPYLFKVSVSDNGKPPMVAQAMARVVL--LKYQP---QQDQQRTSIQESAALGTRVFTLL 449 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 P NA YSI ++ F ++ G ++ LDYE+ K + A Sbjct: 450 TAKPIR--NA--RYSIVSPLET-KFRVDPYSG----DVRVRSGLDYETV-KTHRFTAEAR 499 Query: 771 SPPLWND-VRVEILVT--DVNDNAP--VMKDFQIIFNNYKDCFPVGPFG----RVPAYDA 821 + D +++++T D NDN P M ++ Y P+ D+ Sbjct: 500 NTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDS 559 Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMT 850 D+ ++YR+++ N + LN TGS+T Sbjct: 560 DLNGIVRYRLIT-NPGSHFALNAVTGSIT 587 Score = 130 bits (314), Expect = 2e-29 Identities = 99/329 (30%), Positives = 148/329 (44%), Gaps = 16/329 (4%) Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G I +A LD++ +R Y L V DSG SDTA + + + DAN+ AP FE Y+A Sbjct: 1214 GEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAV 1273 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V ED IG +L V A D D GI YS++ QF INP TG + NK Sbjct: 1274 VREDVDIGERLLRVRAFDEDTGIYKIFKYSIAG-------GDPQGQFKINPDTGDLYINK 1326 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE S ++LT+ A + P V + V+DVNDN P FK ++Y + E+ Sbjct: 1327 SLDREKNSNHILTIRATNIAPPYWYGEASVGVQVLDVNDNGPQFKPEVYNVFVPENTPPP 1386 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + ++ TD D ++ + E + GV++T +RE A ++L Sbjct: 1387 YVIEKLEVTDPDSDPQNGGPFKFGIRSGNEKNLFELTEDGVLKTRVTFNREETAKYELVV 1446 Query: 658 VAIDGGTPPQ---SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 A D P+ S V + + D ND+ L + E G IG++ D Sbjct: 1447 WAEDNAKHPEKPIKSFASVFVHVRDRNDNQHEAGYLELVLNVLEGKFGGGIIGKVFVKDI 1506 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 D + + +S +FS++ G+ Sbjct: 1507 DTDDERLYELIDR---ESEAFSVDRLSGA 1532 Score = 128 bits (309), Expect = 6e-29 Identities = 101/371 (27%), Positives = 167/371 (45%), Gaps = 14/371 (3%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FRID +G ++ +LD E Y + VK D P+S S TA++ V ++D ND P+ Sbjct: 1207 FRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLS--FSDTASLTVEVLDANDRAPR 1264 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F +Y+ V ED+ + + + +++A D D G +Y+I GG+ Q QF I+ +GD+ Sbjct: 1265 FEPLSYSAVVREDVDIGER--LLRVRAFDEDTGIYKIFKYSIAGGDPQGQFKINPDTGDL 1322 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + K+LD E+ ++ L IRA + P + + + DVNDN P+F ++ V EN Sbjct: 1323 YINKSLDREKNSNHILTIRATNIAPPYWYGEASVGVQVLDVNDNGPQFKPEVYNVFVPEN 1382 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 P Y I +++ D D + + +T D G + T +RE Sbjct: 1383 TPPPYVIEKLEVTDPDSDPQNGGPFKFGIRSGNEKNLFELTED---GVLKTRVTFNREET 1439 Query: 330 AKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL--AEDEPPGTPVV 386 AKY+L+V A D P + + G E+ L E + G + Sbjct: 1440 AKYELVVWAEDNAKHPEKPIKSFASVFVHVRDRNDNQHEAGYLELVLNVLEGKFGGGIIG 1499 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 + D D D+ YE+ + FS+ +G +++P E + VS DS Sbjct: 1500 KVFVKDIDTDDERLYELIDRESEA-FSVDRLSG---AVISKPNPPSGEFSMRVKVSDRDS 1555 Query: 447 GGRSDTAMVQI 457 G + + V+I Sbjct: 1556 GFQPRVSTVKI 1566 Score = 122 bits (294), Expect = 4e-27 Identities = 99/335 (29%), Positives = 159/335 (47%), Gaps = 39/335 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ P F Y ++ E A GTTVL++ A D D G N + Y +E Sbjct: 723 KIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVE------ 776 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F +D +G + T+ LD E ++ LV A D +P Sbjct: 777 -----------------SQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPAR-- 817 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TA + V + + NDN P+FS+ Y V V ED + ++A ++ATD D N + Y Sbjct: 818 -NGTARVIVELTNVNDNAPRFSQSLYNVFVAEDAG--SDQLVATVQATDKD---NDPVTY 871 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINIR 248 +I G+ F I++ +G + LV E + Y + I A DG S++ +++ I+ Sbjct: 872 SIASGDNTTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHVSQA---MVIVAIQ 928 Query: 249 DVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVN++ P F + + V E+ P +++V A D D G N E+ Y++ + G + Sbjct: 929 DVNNHKPVFTDCASYHPVVMEDDPPNTFVMQVHADDQDTGANGEVIYSI--EKPPGALSY 986 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 ID ++G V T DRE + YQ+ + DGG Sbjct: 987 -FAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGG 1020 Score = 118 bits (284), Expect = 7e-26 Identities = 92/324 (28%), Positives = 147/324 (45%), Gaps = 17/324 (5%) Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD--PK 623 +++I + DVNDN P+F Q +Y + E+ G + Q A D D G N R+ Y + Sbjct: 4 ELKIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFED 63 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 R + F I P +GV+ LDRE ++ H L A D G P S + I ++D+ND Sbjct: 64 SRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDH 123 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 P F S I N+P + + + RA DPD G N +V YSI G+ FS+ GS Sbjct: 124 APRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGS 183 Query: 744 --DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 +L T+ +D + + R+++ D+R+ I V P + Sbjct: 184 LFLDEKLTTLEPIDIKIQARDMGQPERSSTA----DIRIFI---HVQAGPPQFLSSPFV- 235 Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP- 860 N + P G F V A D + Y I+SGN A L+ G +T L+ Sbjct: 236 GNVTENEPKGAF--VVHISAASLDPVMYSIVSGNEAGNFRLHPGVGWLTTVRPLDNEKQS 293 Query: 861 --KLATMEVSVTDGVNEIKAMMQL 882 K+ M + + + V++++ ++ + Sbjct: 294 RYKIIVMAMDLKNRVSKVEVIVNV 317 Score = 100 bits (240), Expect = 1e-20 Identities = 103/400 (25%), Positives = 163/400 (40%), Gaps = 24/400 (6%) Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 +E +NA+L Y++ +Y + P ID +G + + LD ET+ Y+L V D G P Sbjct: 1186 EERINAKLKYSL---EYEAKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVP 1242 Query: 345 -PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHY 401 S TA+ F P Y + ED G ++ + A D D Y Sbjct: 1243 LSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRVRAFDEDTGIYKIFKY 1302 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINI 459 I GG+ +G+F I G + + + LD ++ ++LT+ AT+ A V + + Sbjct: 1303 SIAGGDPQGQFKINPDTGD--LYINKSLDREKNSNHILTIRATNIAPPYWYGEASVGVQV 1360 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 D N+ P F+ Y V E+ P + + TD D + NE Sbjct: 1361 LDVNDNGPQFKPEVYNVFVPENTPPPYVIEKLEVTDPDSDPQNGGPFKFGIRSGNE---- 1416 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISVVDVND 576 F + + G + T +RE + Y L V A D + V + V D ND Sbjct: 1417 -KNLFELT-EDGVLKTRVTFNREETAKYELVVWAEDNAKHPEKPIKSFASVFVHVRDRND 1474 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636 N+ N++E G + +V D D + R+ YEL DRE +F +D S Sbjct: 1475 NQHEAGYLELVLNVLEGKFGGGIIGKVFVKDIDTD-DERL-YEL--IDRESEAFSVDRLS 1530 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 G + +K + +K D G P+ STV + +K Sbjct: 1531 GAV-ISKPNPPSGEFSMRVKVSDRDSGFQPRVSTVKIIVK 1569 Score = 92.7 bits (220), Expect = 4e-18 Identities = 75/249 (30%), Positives = 116/249 (46%), Gaps = 32/249 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND +P FE Y A VRE G +L ++A D+D G +Y+I Sbjct: 1253 VEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRVRAFDEDTGIYKIFKYSI-------- 1304 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 Q F+I+ +G L SLDREK + + + ++AT+ A P Sbjct: 1305 -----------AGGDPQGQFKINPDTGDLYINKSLDREKNSNHILTIRATNIAPPY---W 1350 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP-VIAKIKATDADVGANSA--I 187 A++ V ++D NDN PQF + Y V V E+ T P VI K++ TD D + Sbjct: 1351 YGEASVGVQVLDVNDNGPQFKPEVYNVFVPEN---TPPPYVIEKLEVTDPDSDPQNGGPF 1407 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSR--SNTTQLL 244 ++ I GN + F + G + T + E+ Y LV+ A+D P + + + Sbjct: 1408 KFGIRSGNEKNLFELTE-DGVLKTRVTFNREETAKYELVVWAEDNAKHPEKPIKSFASVF 1466 Query: 245 INIRDVNDN 253 +++RD NDN Sbjct: 1467 VHVRDRNDN 1475 Score = 71.7 bits (168), Expect = 8e-12 Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 16/174 (9%) Query: 1185 ITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPAR 1244 +T + DG WH +EI T+ + +D C A G+ TR + Sbjct: 1779 VTGGAMLNDGEWHMIEIHRDETTVRVTVDRCR-----ASNISEGV-------TRSEDRSM 1826 Query: 1245 CEIPTETCHR---FLDLTGPLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSY 1300 CE+ + FL+L PLQ+GG+ + F ++ DF GCI + + + DL S Sbjct: 1827 CEVVGHMKKKKLKFLNLNDPLQLGGIASRDLLFPDLRFHDFNGCIRNLINEGRLYDLKSP 1886 Query: 1301 VADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 N T GC C+ C+ A C + ++C+C G G C +T P Sbjct: 1887 SRQNNTREGCATMDQHCNPNSCHEQATCIGSLNGHVCECNMGRHGDTCKHTTQP 1940 Score = 48.4 bits (110), Expect = 8e-05 Identities = 44/153 (28%), Positives = 66/153 (43%), Gaps = 21/153 (13%) Query: 1416 ATLSDGAWHRIEIKWLGTDISVTVDY----------------GLRTVLMPMLANKIQGQY 1459 A L+DG WH IEI T + VTVD + V+ M K++ Sbjct: 1783 AMLNDGEWHMIEIHRDETTVRVTVDRCRASNISEGVTRSEDRSMCEVVGHMKKKKLKFLN 1842 Query: 1460 IGKIL-IGGLDTTAGLLASDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRAD 1516 + L +GG+ + LL D+ F F GCI+++ L P+ + N R+GC + Sbjct: 1843 LNDPLQLGGI-ASRDLLFPDLRFHDFNGCIRNLINEGRLYDLKSPSRQNNTREGCATMDQ 1901 Query: 1517 -CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548 C + C + C+ S + C C GR G C Sbjct: 1902 HCNPNSCHEQATCIGSLNGHVCECNMGRHGDTC 1934 Score = 37.9 bits (84), Expect = 0.12 Identities = 48/224 (21%), Positives = 92/224 (41%), Gaps = 26/224 (11%) Query: 1123 RRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLR-FSFSLGGG 1181 R RI L+++ T+ +G +L + E+ ++ L+LV + R + ++F+ G Sbjct: 1962 RETRIDLRVR--TRDLNGGVLLHSEGTEKGEYSTLQLVPMKDQRKREILIVVYAFNTGDR 2019 Query: 1182 KSEITVEG-NVGDGSWHTVEIEYFNR--TITMILDDCDKVLSLAGAADFGLKYACANFTR 1238 +E+ NVGDG W ++ + + T+T+ D + + + + + L T Sbjct: 2020 GAEVRASDVNVGDGKWCSIRVNRYRNAATLTVEKDGVNYIRTRSTRGNHSLIMLDPIMTF 2079 Query: 1239 KVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISD-----FYIDHK 1293 R + T R N +S ++ DF+GCI D + + H Sbjct: 2080 VGGLPRVVHASVTTRRLRRR----------NRSTS---RDNDFIGCIDDLRFHGYRLHHN 2126 Query: 1294 FIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYIC 1337 + G + GC + + C ++PC C D W ++C Sbjct: 2127 GTKAFATAISKGVVEGC--ESNSCLASPCPTFQWCYDAWRMHVC 2168 Score = 33.5 bits (73), Expect = 2.5 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 6/61 (9%) Query: 1482 FEGCIQDVRIGTAQSLLN-----RPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSST 1536 F GCI D+R + N + + V +GC+S + C+ S CP + C +W Sbjct: 2109 FIGCIDDLRFHGYRLHHNGTKAFATAISKGVVEGCESNS-CLASPCPTFQWCYDAWRMHV 2167 Query: 1537 C 1537 C Sbjct: 2168 C 2168 >SB_28228| Best HMM Match : Cadherin (HMM E-Value=0) Length = 838 Score = 227 bits (554), Expect = 1e-58 Identities = 217/793 (27%), Positives = 351/793 (44%), Gaps = 81/793 (10%) Query: 28 YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87 Y+ VRE G + A D D G NA V Y+I +N ED+ Sbjct: 3 YKVFVRENLQGGHVIGQFAARDPDKGANARVTYSI-------INFEDSRS---------D 46 Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 ++F I +G L ++LDRE ++R+ + ++A D P R+S A I + + D ND+ Sbjct: 47 NLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVP---RMSGLAQIVIIVDDVNDHA 103 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P+FS ++ V + ++ + + + +A D D G N +RY+II GN Q FSI+ + G Sbjct: 104 PRFSSGSFHVEI--PLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDG 161 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 + L + L + + I+A+D G P RS+T + I I V P+F +S F +V+ Sbjct: 162 SLFLDEKL--TTLEPIDIKIQARDMGQPERSSTADIRIFIH-VQAGPPQFLSSPFVGNVT 218 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN P G +V + A D + Y++ + GN + P GW+ T LD E Sbjct: 219 ENEPKGAFVVHISAASLD-----PVMYSIVSGNEAGN----FRLHPGVGWLTTVRPLDNE 269 Query: 328 TQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 Q++Y+++V A D + G E + +D G+ V+ Sbjct: 270 KQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVM 329 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 + A DAD + L Y I R FS+ N G++T + L + Y+ VS +D+ Sbjct: 330 VIDAVDADRSDILSYRIEDEKARRYFSV---NNEGVVTSTRVLR-DLDSPYLFKVSVSDN 385 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 G A + Y P + S+ E A +GT V + T + NA+ Y Sbjct: 386 GKPPMVAQAMARVV-LLKYQP--QQDQQRTSIQESAALGTRVFTL-LTAKPIR-NAR--Y 438 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 S+ S + + +F ++P +G + LD ET+ + T AR+ + D Sbjct: 439 SIVSPL--------ETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYANID 490 Query: 567 VEISVVDVNDNEPVFKQQ----LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 V I+V D NDN P F LY A + + + T V + ATD D LNG + Y L Sbjct: 491 VIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT 550 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 F ++ +G I T D + ++L A D G P + +V+++ Sbjct: 551 NPGSH--FALNAVTGSITTRGRSDL-FLPWYNLTVEAFDLGKPSLVTRAVVNVR---TGQ 604 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 PP+F FY+ EN+P G TIG + D +++ Y + G F L++ G Sbjct: 605 FPPLFSRKEYAFYVDENTPRGYTIGTV---DAKSFSGSLLEYMVIEGSGHKRFVLDSVTG 661 Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASP------PLWNDVRVEILVTDVNDNAPVMKD 796 L LD+E Y + + A PL ++ V+I++ D+NDN P + Sbjct: 662 ----RLTLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEADVKIVLRDLNDNPP--EF 715 Query: 797 FQIIFNNYKDCFP 809 F++ +Y+D P Sbjct: 716 FEL---SYRDTLP 725 Score = 168 bits (409), Expect = 5e-41 Identities = 204/799 (25%), Positives = 332/799 (41%), Gaps = 95/799 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH+P F + + + V +A D D G N V Y+I Sbjct: 94 IIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSI-------- 145 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 Q F I+ G+L L + + ++A D P Sbjct: 146 -----------IQGNKQGYFSINHIDGSLFLDEKLTT--LEPIDIKIQARDMGQP---ER 189 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SSTA I + I PQF + +V E+ + I A D + Y+ Sbjct: 190 SSTADIRI-FIHVQAGPPQFLSSPFVGNVTEN--EPKGAFVVHISAASLD-----PVMYS 241 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ GN F + G ++ V+ LD E+ Y++++ A D +R + ++++N+ +V Sbjct: 242 IVSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMD--LKNRVSKVEVIVNVLNV 299 Query: 251 NDNAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 NDN P+F + + +V ++V +G ++ + A DAD + L+Y + D+ + Sbjct: 300 NDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDADR--SDILSYRIEDEKARRYFSV 357 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 + V TS ++ R+ + Y V+ +D G PP A A Sbjct: 358 ------NNEGVVTSTRVLRDLDSPYLFKVSVSDNGKPPMVAQAMARVVLLKYQP-----Q 406 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Q + E GT V TL + R Y I +F + +G + V Sbjct: 407 QDQQRTSIQESAALGTRVFTLLTAKPIRNAR--YSIVSP-LETKFRVDPYSGD--VRVRS 461 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFE----NAPYTASVFED 481 LD++ + + T A ++ +D A + + IT D+N+ P F N Y A V + Sbjct: 462 GLDYETVKTHRFTAEARNTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVN 521 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 T V + ATD D +N + Y L + + F +N TG+ITT D Sbjct: 522 PIADTRVFTLEATDPDSDLNGIVRYRL--------ITNPGSHFALNAVTGSITTRGRSDL 573 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTS 599 + Y LTV A D G PSL V +VV+V + P+F ++ Y + E+ G + Sbjct: 574 -FLPWYNLTVEAFDLGKPSL-----VTRAVVNVRTGQFPPLFSRKEYAFYVDENTPRGYT 627 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE---SVATHDLK 656 + G DA + Y + + FV+D +G + + LD E ++ + Sbjct: 628 I---GTVDAKSFSGSLLEYMVIEGSGHK-RFVLDSVTGRLTLPEPLDFERDSNIYLITVS 683 Query: 657 AVAIDGGT-PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D P S V I + D+ND+PP F + E++P+GTT+ + A D D Sbjct: 684 AKETDNSLLRPLKSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLD 743 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIRAASPPL 774 G N HY + +S FS++ G + T LD+E +P + +V + + P Sbjct: 744 SGVNGQFHYFV----ESQFFSVDPYTG----WITTKRPLDFETNPTHSFLVVAQDSGNPA 795 Query: 775 WN-DVRVEILVTDVNDNAP 792 N RV + +T+VNDNAP Sbjct: 796 RNGTARVIVELTNVNDNAP 814 Score = 161 bits (391), Expect = 7e-39 Identities = 126/417 (30%), Positives = 195/417 (46%), Gaps = 34/417 (8%) Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 RY+I+ + +F +D SGDV + LDYE V+++R A++ + ++I + Sbjct: 437 RYSIVSP-LETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYANIDVIITV 495 Query: 248 RDVNDNAPRFYTS----LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 D NDN PRF + L+ VS N + ++A D D +N + Y + Sbjct: 496 EDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT----- 550 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 N ++ +G + T G+ D Y L V A D G P + T Sbjct: 551 NPGSHFALNAVTGSITTRGRSDLFLPW-YNLTVEAFDLGKP---SLVTRAVVNVRTGQFP 606 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F +Y + E+ P G + T+ A + L Y + G+ RF + S GR + Sbjct: 607 PLFSRKEYAFYVDENTPRGYTIGTVDAKSFS-GSLLEYMVIEGSGHKRFVLDSVTGR--L 663 Query: 424 TVAQPLDFKQERR-YVLTVSATDSGGR-----SDTAMVQINITDANNYAPVFENAPYTAS 477 T+ +PLDF+++ Y++TVSA ++ A V+I + D N+ P F Y + Sbjct: 664 TLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEADVKIVLRDLNDNPPEFFELSYRDT 723 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E AP+GTTVL V+A D D G+N Q Y + S+ F ++P TG ITT + Sbjct: 724 LPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQF-----------FSVDPYTGWITTKR 772 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 LD ET + V A+D G P+ + T V + + +VNDN P F Q LY + EDA Sbjct: 773 PLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVAEDA 829 Score = 153 bits (372), Expect = 1e-36 Identities = 169/624 (27%), Positives = 269/624 (43%), Gaps = 58/624 (9%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FR+ G L T LD EK +RY ++V A D + +R+S I VN+++ NDN P+ Sbjct: 251 FRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMD----LKNRVSKVEVI-VNVLNVNDNKPK 305 Query: 150 FSEKTYTV---SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 F + +V +D++V ++ I A DAD + + Y I + FS+++ Sbjct: 306 FVNIRNGIIEGNVLKDVAVGSRVMV--IDAVDAD--RSDILSYRIEDEKARRYFSVNN-E 360 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G V+ + L + Y + D G P + + + TS+ QES Sbjct: 361 GVVTSTRVLR-DLDSPYLFKVSVSDNGKPPMVAQAMARVVLLKYQPQQDQQRTSI-QESA 418 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 + + ++++ + NA Y++ ++ +DP SG V LD Sbjct: 419 ALGTRV-FTLLTAKPIR-----NAR--YSIVSP-----LETKFRVDPYSGDVRVRSGLDY 465 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP----GQYEVELAEDEPPG 382 ET ++ A + D A F G Y ++ + Sbjct: 466 ETVKTHRFTAEARNTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIAD 525 Query: 383 TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 T V TL ATD D D + Y + N F++ + G IT D Y LT Sbjct: 526 TRVFTLEATDPDSDLNGIVRYRLIT-NPGSHFALNAVTGS--ITTRGRSDLFLPW-YNLT 581 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 V A D G S +N+ + P+F Y V E+ P G T+ V A Sbjct: 582 VEAFDLGKPSLVTRAVVNVR-TGQFPPLFSRKEYAFYVDENTPRGYTIGTVDAKS----- 635 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGG-- 557 + SL + E H ++FV++ TG +T + LD E S YL+TV+A++ Sbjct: 636 ---FSGSLLEYMVIEGSGH--KRFVLDSVTGRLTLPEPLDFERDSNIYLITVSAKETDNS 690 Query: 558 -VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 + L DV+I + D+NDN P F + Y + E A VGT+V V A D D G+NG+ Sbjct: 691 LLRPLKSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQF 750 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 HY + E F +DP +G I T + LD E+ TH VA D G P ++ T V ++ Sbjct: 751 HYFV-----ESQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVE 805 Query: 677 IEDINDSPPVFESDCLTFYISENS 700 + ++ND+ P F +++E++ Sbjct: 806 LTNVNDNAPRFSQSLYNVFVAEDA 829 Score = 140 bits (339), Expect = 1e-32 Identities = 159/610 (26%), Positives = 273/610 (44%), Gaps = 65/610 (10%) Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 +++ V EN+ G+ I + A D D+G NA +TY++ + + + + +L +I P +G + Sbjct: 2 VYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNL-FSIHPFTGVLTA 60 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 LDRE +++ L + A D G P S A F G + VE+ + P Sbjct: 61 LSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTP 120 Query: 381 PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR----GLITVAQPLDFKQE 434 P + V A D D + + Y I GN +G FSI +G +T +P+D K Sbjct: 121 PDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIK-- 178 Query: 435 RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 + A D G RS TA ++I I P F ++P+ +V E+ P G V+ +S Sbjct: 179 ------IQARDMGQPERSSTADIRIFI-HVQAGPPQFLSSPFVGNVTENEPKGAFVVHIS 231 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A D + YS+ S NEA F ++P G +TT + LD E S Y + V Sbjct: 232 AASLD-----PVMYSIVS--GNEA-----GNFRLHPGVGWLTTVRPLDNEKQSRYKIIVM 279 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANIMEDALVGTSVSQVGATDAD 609 A D + + +V ++V++VNDN+P F + + N+++D VG+ V + A DAD Sbjct: 280 AMD--LKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDAD 337 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 + + Y ++ D + + GV+ + + L R+ + + K D G PP + Sbjct: 338 --RSDILSYRIE--DEKARRYFSVNNEGVVTSTRVL-RDLDSPYLFKVSVSDNGKPPMVA 392 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + + + + P + D I E++ +GT + + P NA YSI Sbjct: 393 QAMARVVL--LKYQP---QQDQQRTSIQESAALGTRVFTLLTAKPIR--NA--RYSIVSP 443 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVT--D 786 ++ F ++ G ++ LDYE+ K + A + D +++++T D Sbjct: 444 LET-KFRVDPYSG----DVRVRSGLDYETV-KTHRFTAEARNTRDNTDYANIDVIITVED 497 Query: 787 VNDNAP--VMKDFQIIFNNYKDCFPVGPFG----RVPAYDADVTDKLQYRILSGNNANLI 840 NDN P M ++ Y P+ D+D+ ++YR+++ N + Sbjct: 498 SNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT-NPGSHF 556 Query: 841 LLNETTGSMT 850 LN TGS+T Sbjct: 557 ALNAVTGSIT 566 Score = 98.3 bits (234), Expect = 8e-20 Identities = 83/305 (27%), Positives = 133/305 (43%), Gaps = 17/305 (5%) Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTN 642 +Y + E+ G + Q A D D G N R+ Y + R + F I P +GV+ Sbjct: 2 VYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTAL 61 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LDRE ++ H L A D G P S + I ++D+ND P F S I N+P Sbjct: 62 STLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPP 121 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS--DKAELVTMVDLDYESPR 760 + + + RA DPD G N +V YSI G+ FS+ GS +L T+ +D + Sbjct: 122 DSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIKIQA 181 Query: 761 KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 + R+++ D+R+ I V P + N + P G F V Sbjct: 182 RDMGQPERSSTA----DIRIFI---HVQAGPPQFLSSPFV-GNVTENEPKGAF--VVHIS 231 Query: 821 ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP---KLATMEVSVTDGVNEIK 877 A D + Y I+SGN A L+ G +T L+ K+ M + + + V++++ Sbjct: 232 AASLDPVMYSIVSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMDLKNRVSKVE 291 Query: 878 AMMQL 882 ++ + Sbjct: 292 VIVNV 296 Score = 60.9 bits (141), Expect = 1e-08 Identities = 47/153 (30%), Positives = 69/153 (45%), Gaps = 26/153 (16%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ P F Y ++ E A GTTVL++ A D D G N + Y +E Sbjct: 702 KIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVE------ 755 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F +D +G + T+ LD E ++ LV A D +P Sbjct: 756 -----------------SQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPAR-- 796 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 + TA + V + + NDN P+FS+ Y V V ED Sbjct: 797 -NGTARVIVELTNVNDNAPRFSQSLYNVFVAED 828 >SB_27857| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2418 Score = 221 bits (539), Expect = 9e-57 Identities = 216/804 (26%), Positives = 348/804 (43%), Gaps = 79/804 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NV D ND +PVFE QY ++ E T+VL ++ATD+D G N + Y ++ Sbjct: 237 RVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMK------ 290 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 NP V F ID +G + +LD ++T+ + A D+ P R Sbjct: 291 -NP-------------VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDP--PR 334 Query: 130 LSSTATIHVNI------------IDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 S+ AT+ +++ D +N P F + YT S+ ED + ++A Sbjct: 335 TSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFP--PKGALLVMRA 392 Query: 177 TDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQDG 232 D D +G N +RY++ GN +F+ID SG V+L ++DYE + Y L + A D Sbjct: 393 ADNDPIGPNKRLRYSL-SGNGVSKFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQ 451 Query: 233 GSPSRSNTTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 G S S TTQLLI I+DV N N+PRF +SEN+ + V A D+D N Sbjct: 452 GPGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNP 511 Query: 291 ELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSA 348 G L + +D +G V + LDRE ++Y L+V A+D PRS+ Sbjct: 512 SSPDGKVVYSIVGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSS 571 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 F Y ++ E++P GT V + DADE Y + T Sbjct: 572 RLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPSYTVI---T 628 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN--NYA 466 G + G+I ++ LD + L V S S TA Q+NIT + N Sbjct: 629 PG-VPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRP 687 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 PVF+N PY+ V E+ + ++A DS ++ + Y+L+ D F + Sbjct: 688 PVFKNTPYSVKVPEEMGPLPNLFCIAAVDS---LSRPVQYTLAPGA--------DGLFEV 736 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + +G + T + E + Y L + AR V ++ + + + V + D P F Y Sbjct: 737 DKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEVA-SASLTVEVTEEKD-LPKFSSDSY 794 Query: 587 TANIMEDALVGTSVSQ-VGATDADVGLNG-RIHYELDPKDREEGSFVIDPASG----VIR 640 + E A GT+++ + D+D + E +F + SG ++ Sbjct: 795 QLTVDESAAPGTTLAPGLLIIDSDTSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQ 854 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 LD + + A D +T V + + D+ND P F + + ++ Sbjct: 855 AGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSST 914 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 P G+++ ++A D D G NA V Y + ++S F L +D +L T L +P Sbjct: 915 PAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFIL-----NDNNQLSTASTL---TPN 966 Query: 761 KKYELVIRAASPPLWNDVRVEILV 784 +Y+L+IRA+ N ++ V Sbjct: 967 VRYQLLIRASDSATRNPSSAQVPV 990 Score = 218 bits (533), Expect = 5e-56 Identities = 209/702 (29%), Positives = 319/702 (45%), Gaps = 69/702 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ P++ ++ A V + +G V L+A D+D G + V Y ++ + D Sbjct: 1741 EVVVLDVNDNRPIWMERERLARVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSPSNDA 1800 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + Q F I+ ++ + SL K RY + V A D P R Sbjct: 1801 KRKRRSPP---------QHPFTINPKTRQMEVAGSL---KDQRYDLDVFAFDYGIP---R 1845 Query: 130 LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L+S T T++V+ P+FS+ +Y V ED ++ I A GA + Sbjct: 1846 LTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLS--LVGIILARSIS-GAR--LD 1900 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINI 247 Y I+ GN +F I G + L LD+E+ ++ Y L ++A + +T + I++ Sbjct: 1901 YKIVSGNVGDKF-IAMGDGRILLNSLLDFERDQTQYNLKVKATEQIPDGLDSTVDVKIDV 1959 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-----LTYTMTDKDYT 302 + ND+ P F L+ + E+ +G + V A D D + LTY++ Sbjct: 1960 INANDHFPYFDQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQ 2019 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 G IDP +G + S LD E Q + L V ATD G Sbjct: 2020 GG---KFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDN 2076 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F+ YE +AE G + + A DAD D + Y GG + FS+ G + Sbjct: 2077 RPTFLKSAYEFRVAEGAATGESLAIVVAVDADGD-AVTYSKAGGALQ--FSVDQSTG--V 2131 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 IT+ LD + +Y L V A DSGG + T V N+ DANN P F N T S+ E+ Sbjct: 2132 ITLNSALD-PNKNQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQFTNCG-TVSIREND 2189 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P T + ++ATD+D G N QITYS+ + S++ + F I P+TG + + LDRE Sbjct: 2190 PRDTKITQLTATDADRGQNGQITYSIE-DASSQTL------FSIEPRTGVVRSLTSLDRE 2242 Query: 543 TMSGYLLTVTARDGGVPSLSDTTD-------VEISVVDVNDNEPVFKQQLYTANIMEDAL 595 Y + A DG S D ++ + I+V DVNDN P F Y ++ A Sbjct: 2243 NKDSYNAIIKAEDGS--SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAP 2300 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN---KALDRES--- 649 G+++ V ATDAD G N +I Y L D G F +D +SG++RTN L E+ Sbjct: 2301 NGSNILTVQATDADSGSNAKIKYAL--LDSAGGLFRLD-SSGILRTNTNPARLQLETGKK 2357 Query: 650 ----VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 V+ D++++A G P + + I+I N+ PP F Sbjct: 2358 LLLEVSAKDVESIA--GTQPGKPTKYTTQIEILVSNEEPPKF 2397 Score = 216 bits (528), Expect = 2e-55 Identities = 248/898 (27%), Positives = 389/898 (43%), Gaps = 94/898 (10%) Query: 10 QINVLDCNDHSPVFEMQQ---YEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIE 63 +I +LD N+ PVF++ Q YE V+EG + T V L+ ATD+D + Y+I Sbjct: 116 RITILDVNNFHPVFQLSQGEHYEGFVKEGTAENTIVEGLEQCHATDRD--TSGIRGYSI- 172 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALL--TRASLDREKVARYTVL-VKAT 120 VQ + R +L T + R+ Y +L V+ T Sbjct: 173 ---------ISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDNNPYIMLTVQVT 223 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 D +P S TA I VN+ D ND P F Y ++ E+ + + + +++ATD D Sbjct: 224 DGGNPSH---SGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTS--VLRVRATDKD 278 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN- 239 G N I Y + F+ID+++G + + KTLDY + L I A+D G P R++ Sbjct: 279 DGTNGGI-YYYMKNPVNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDPPRTSA 337 Query: 240 --TTQLLI--NIR--------DVNDNA-PRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 T ++ + NI+ D +N P F S + S+ E+ P +++ ++A D D Sbjct: 338 EATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFPPKGALLVMRAADNDP 397 Query: 287 -GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK---YQLLVTATDGG 342 G N L Y++ +GN IDP SG V + +D E Y L VTATD G Sbjct: 398 IGPNKRLRYSL-----SGNGVSKFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQG 452 Query: 343 DPPRSATATXXXXXXXXXXXXXX--FMPGQYEVELAEDEPPGTPVVTLTATDADE----- 395 SAT F P Q +E++E+ + V T++ATD+D Sbjct: 453 PGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNPS 512 Query: 396 --DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSG--GRS 450 D ++ Y I GG G F + S G + VA P LD + +Y L V A+D+ RS Sbjct: 513 SPDGKVVYSIVGGTGLGVFRVDSNTGE--VKVAVPSLDREGTSQYTLVVKASDNATFPRS 570 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 + IN+ D ++ P F Y A V E+ P GT V VV D+D G N T Sbjct: 571 SRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPSYT----- 625 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 V + I P TG I T+K LD+ +S L V R S + V I+ Sbjct: 626 ------VITPGVPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNIT 679 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V+ + PVFK Y+ + E+ ++ + A D+ L+ + Y L P +G F Sbjct: 680 VISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAAVDS---LSRPVQYTLAP--GADGLF 734 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 +D SG + T + + E+V ++L+ A +S + +++ + D P F SD Sbjct: 735 EVDKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEVASASLT-VEVTEEKDLPK-FSSD 792 Query: 691 CLTFYISENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAEL 748 + E++ GTT+ + D D + S++ ++ ++ E Q S + L Sbjct: 793 SYQLTVDESAAPGTTLAPGLLIIDSDTSSDQ-FDCSMEAITSLHTLYNFEVTQQSGRCFL 851 Query: 749 VTMVDLDYESP-RKKYELVIRAASPPLWN---DVRVEILVTDVNDNAPVMKDFQIIFNNY 804 ++ KY +RA N +VE+ V DVND+ P + + + Sbjct: 852 RVQAGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQ-ESYWLSV 910 Query: 805 KDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859 P G V A D D+ +++Y +L N+ +LN+ T S L NV Sbjct: 911 PSSTPAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFILNDNNQLSTAS-TLTPNV 967 Score = 212 bits (517), Expect = 4e-54 Identities = 208/795 (26%), Positives = 352/795 (44%), Gaps = 78/795 (9%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADTLNPEDAXXXX 79 P F +Y S+RE +L ++A D D IG N + Y++ + + ++ Sbjct: 366 PYFPQSRYTFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSL---SGNGVSK------- 415 Query: 80 XXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSSTATI 136 F ID SG + S+D E Y + V ATDQ P S ++ I Sbjct: 416 ----------FAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQG-PGSLSATTQLLI 464 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA----IRYAI 191 + +D+N N P+F + + + E++ N ++ + ATD+D VG S+ + Y+I Sbjct: 465 EIQDVDENKNSPRFDPQQAILEISENLK--QNSLVTTVSATDSDSVGNPSSPDGKVVYSI 522 Query: 192 IGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 +GG F +DS +G+V + V +LD E Y LV++A D + RS+ L+IN+ D Sbjct: 523 VGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDE 582 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 +DN P F ++ V EN P G + V DADEG N +YT+ +P Sbjct: 583 DDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNP--SYTVITPG------VPYK 634 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+P +G + TS LD+ + +L V ++A F Sbjct: 635 IEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTP 694 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y V++ E+ P + + A D+ + Y + G G F + +GR + + Sbjct: 695 YSVKVPEEMGPLPNLFCIAAVDS-LSRPVQYTLAPG-ADGLFEVDKDSGR--LHTKNSFN 750 Query: 431 FKQERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 ++ RY L + A T S +A + + +T+ + P F + Y +V E A GTT+ Sbjct: 751 YENVDRYNLRIEARTSSVQEVASASLTVEVTEEKDL-PKFSSDSYQLTVDESAAPGTTLA 809 Query: 490 V-VSATDSDVGINAQITYSLSSEISNEAVA--HHDQQFVINPQTGA----ITTNKLLDRE 542 + DSD T S + S EA+ H F + Q+G + LD Sbjct: 810 PGLLIIDSD-------TSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQAGGKLDAH 862 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y V A D ++ T VE++V+DVND++P F Q+ Y ++ G+S+ Sbjct: 863 LASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVT 922 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+G N ++ YEL ++ E F+++ + + T L + L A D Sbjct: 923 VQAEDMDIGTNAQVRYELLRQENSE-RFILND-NNQLSTASTLTPN--VRYQLLIRASDS 978 Query: 663 GT-PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 T P S+ V V++ + ++SP VF+ + E+S T + +A + Sbjct: 979 ATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLPEDSSANTLVFTAKATRSGSSRGSR 1038 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASPPLWND 777 + S+ G FS++ D ++ + LD+E+ + + + +RA + L ++ Sbjct: 1039 TNSSVIG---EAMFSIK----PDTGQVYLIKKLDFET-KSYFPIAVRAKYSGGAIELASE 1090 Query: 778 VRVEILVTDVNDNAP 792 V ++ + DVNDN P Sbjct: 1091 VVAKVTIVDVNDNGP 1105 Score = 210 bits (513), Expect = 1e-53 Identities = 192/633 (30%), Positives = 289/633 (45%), Gaps = 45/633 (7%) Query: 326 RETQ-AKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 R TQ + Y ++V ATDG D + F Y + E G Sbjct: 1106 RYTQGSSYIIIVVATDGATDGSQKIQKYTVNVQVLDTPRPPSFPQKTYSAPVTETAGVGD 1165 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 V T+ A + + L Y GN F + NG G+I+VA+ LD ++ Y L + Sbjct: 1166 TVTTVRAVYSKPNAFLKYTFVSGNEDNTFCV---NGFGIISVAKSLDREKVAGYTLGMRV 1222 Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINA 502 T G D V +N+TD N+ AP F +A Y S+ E T +L V A D D G N Sbjct: 1223 T-LGQHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNG 1281 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-L 561 +I YS+ S + + D+ F I+ TG ITT LD ET + L + A D G P L Sbjct: 1282 KILYSILSGVHPD----WDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSPKRL 1337 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 S V+I V+D NDN PVF Y A I A+ GTSV QV ATD D G NG+I Y + Sbjct: 1338 SGIAQVDIDVIDRNDNSPVFAAAFYRAKISLGAVKGTSVLQVHATDLDSGQNGQITYSI- 1396 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 + EE +F I+ GVI +K+L + LK A D P+S +V V I + + Sbjct: 1397 IQGNEEEAFTIN-EQGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVY-LP 1454 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D PP+F +T Y+ E P + ++A + + Y++ G+++ F + Sbjct: 1455 DGPPMFVVSPVTVYVKEGVPANHRVAGVKA-----ATSEALTYTLLSGNEAGMFRINPST 1509 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTDVNDNAPVMKDF--- 797 GS L +LDYE R++YEL I A + V + I+V ++NDN P D Sbjct: 1510 GS----LDATRELDYEE-RRRYELKIEARDTRDRSAMVELIIIVVNINDNKPTFVDIVDG 1564 Query: 798 QIIFNNYKDCFPVG-----PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852 QI C P R+ A+D D D++ + I+ + +L + ++ G +T Sbjct: 1565 QIDRKAIGTCSPTDIAEGEVITRLGAFDRD-GDEITF-IVPDDVKDLFKI-DSRGVVTAK 1621 Query: 853 PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLN---DMTAEQFL 909 + ++PK+ V D E + VRL+ + VR+N D + Sbjct: 1622 KPIE-DLPKIYPFNVKALDN-GEPPQETDVKVRLVFVHYRPDQKHVRVNVREDTPTGSVI 1679 Query: 910 SPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDV 942 + + +F +G+ +++ K N FSV+ + DV Sbjct: 1680 ATVRRYFPNGIVSLLLPEKAN---FSVRANGDV 1709 Score = 208 bits (507), Expect = 6e-53 Identities = 217/817 (26%), Positives = 368/817 (45%), Gaps = 89/817 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V ++ VF+ Y ++ E +S+ T V T KAT + + ++ ++ Sbjct: 992 VSVYSPSESPIVFDKSSYNQNLPEDSSANTLVFTAKATRSGSSRGSRTNSSVIGEAMFSI 1051 Query: 71 NPEDAXXXXXXXXXX-VQDVFRIDGR---SGALLTRASLDREKVA---------RYT--- 114 P+ + F I R SG + AS KV RYT Sbjct: 1052 KPDTGQVYLIKKLDFETKSYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRYTQGS 1111 Query: 115 ---VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171 ++V ATD A+ S ++ T++V ++D P F +KTY+ V E V D + Sbjct: 1112 SYIIIVVATDGATDGSQKIQKY-TVNVQVLD-TPRPPSFPQKTYSAPVTETAGVGDT--V 1167 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 ++A + N+ ++Y + GN F ++ G +S+ K+LD E+V Y L +R Sbjct: 1168 TTVRAVYSK--PNAFLKYTFVSGNEDNTFCVNGF-GIISVAKSLDREKVAGYTLGMRVTL 1224 Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDADEGVNA 290 G + T + +N+ D+ND+AP F +++++ S+ E + I+ V A D D G N Sbjct: 1225 G---QHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNG 1281 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SAT 349 ++ Y++ + + D ID +G + T LD ET + L + A D G P R S Sbjct: 1282 KILYSILSGVHP-DWDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSPKRLSGI 1340 Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407 A F Y +++ GT V+ + ATD D ++ ++ Y I GN Sbjct: 1341 AQVDIDVIDRNDNSPVFAAAFYRAKISLGAVKGTSVLQVHATDLDSGQNGQITYSIIQGN 1400 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465 F+I N +G+I V + L ++ L V A D RS + V+IN+ + Sbjct: 1401 EEEAFTI---NEQGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVYLPDG- 1456 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P+F +P T V E P V V A S+ +TY+L S NEA F Sbjct: 1457 PPMFVVSPVTVYVKEGVPANHRVAGVKAATSEA-----LTYTLLS--GNEA-----GMFR 1504 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---- 581 INP TG++ + LD E Y L + ARD S ++ I VV++NDN+P F Sbjct: 1505 INPSTGSLDATRELDYEERRRYELKIEARD--TRDRSAMVELIIIVVNINDNKPTFVDIV 1562 Query: 582 -----KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636 ++ + T + D G ++++GA D D I + + P D ++ F ID + Sbjct: 1563 DGQIDRKAIGTCS-PTDIAEGEVITRLGAFDRD---GDEITF-IVPDDVKD-LFKID-SR 1615 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 GV+ K ++ + + A+D G PPQ + V +++ ++ P + + + Sbjct: 1616 GVVTAKKPIE-DLPKIYPFNVKALDNGEPPQETD--VKVRLVFVHYRP---DQKHVRVNV 1669 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 E++P G+ I +R + PN +V + + +FS+ +++ + LDY Sbjct: 1670 REDTPTGSVIATVRRY----FPNGIVSLLL---PEKANFSVRA-----NGDVILLTPLDY 1717 Query: 757 ESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793 ES ++ + + +R NDV VE++V DVNDN P+ Sbjct: 1718 ES-QQFHRMTVREELGNQTNDVDVEVVVLDVNDNRPI 1753 Score = 205 bits (500), Expect = 5e-52 Identities = 202/718 (28%), Positives = 332/718 (46%), Gaps = 79/718 (11%) Query: 125 PVSDRLSSTA-TIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDAD 180 P + L A T+ + I+D N+ +P F + Y V E +N ++ ++ A Sbjct: 103 PRGETLGGIAITLRITILDVNNFHPVFQLSQGEHYEGFVKE--GTAENTIVEGLEQCHAT 160 Query: 181 VGANSAIR-YAIIGGNTQMQFSIDSL---SGDVS----LVKTLDYEQVRS-----YRLVI 227 S IR Y+II GN + F ++++ SG S ++KT VR L + Sbjct: 161 DRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDNNPYIMLTV 220 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287 + DGG+PS S T + +N+ D ND P F +S ++E+++EN PI S++RV+A D D+G Sbjct: 221 QVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDG 280 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR- 346 N + Y M + V+ TID +G + + LD + K+ L ++A D GDPPR Sbjct: 281 TNGGIYYYMKNP-----VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDPPRT 335 Query: 347 SATATXX-------------XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 SA AT F +Y + ED PP ++ + A D Sbjct: 336 SAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFPPKGALLVMRAADN 395 Query: 394 D---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSG 447 D + RL Y ++ GN +F+I ++ G++T+ +D++ Y LTV+ATD G Sbjct: 396 DPIGPNKRLRYSLS-GNGVSKFAIDPES--GVVTLTDSVDYENTPNNHVYDLTVTATDQG 452 Query: 448 GRSDTA----MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VG--- 499 S +A +++I D N +P F+ + E+ + V VSATDSD VG Sbjct: 453 PGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNPS 512 Query: 500 -INAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGG 557 + ++ YS+ + + F ++ TG + LDRE S Y L V A D Sbjct: 513 SPDGKVVYSI---VGGTGLG----VFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNA 565 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 S + I+++D +DN P F Q +Y A + E+ GT V+ V DAD G N + Sbjct: 566 TFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPS-Y 624 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 + P + I+P++GVIRT+K+LD+ ++T +L+ + +++ V+I + Sbjct: 625 TVITP----GVPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITV 680 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 + PPVF++ + + E + I A D P V Y++ G D F + Sbjct: 681 ISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAAVDSLSRP---VQYTLAPGAD-GLFEV 736 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795 + D L T +YE+ +Y L I A + + +V L +V + + K Sbjct: 737 D----KDSGRLHTKNSFNYENV-DRYNLRIEARTSSV-QEVASASLTVEVTEEKDLPK 788 Score = 204 bits (499), Expect = 6e-52 Identities = 230/886 (25%), Positives = 373/886 (42%), Gaps = 72/886 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTAD 68 +I D D S + E+ ++ + + ++ + + IG + + E++T Sbjct: 1529 KIEARDTRDRSAMVELIIIVVNINDNKPTFVDIVDGQIDRKAIGTCSPTDIAEGEVITRL 1588 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 D V+D+F+ID R + D K+ Y VKA D P + Sbjct: 1589 GAFDRDGDEITFIVPDDVKDLFKIDSRGVVTAKKPIEDLPKI--YPFNVKALDNGEPPQE 1646 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + V+ D +K V+V ED VIA ++ N + Sbjct: 1647 TDVKVRLVFVHYRPD--------QKHVRVNVREDTPT--GSVIATVRR----YFPNGIVS 1692 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + + FS+ + +GDV L+ LDYE + +R+ +R + G +++N + + + Sbjct: 1693 LLL---PEKANFSVRA-NGDVILLTPLDYESQQFHRMTVREELG---NQTNDVDVEVVVL 1745 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN---- 304 DVNDN P + V+ N G + +++A D D+G + + Y + Sbjct: 1746 DVNDNRPIWMERERLARVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSPSNDAKRKRR 1805 Query: 305 --VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXX 361 P TI+P++ + +G L + +Y L V A D G P S T T Sbjct: 1806 SPPQHPFTINPKTRQMEVAGSLKDQ---RYDLDVFAFDYGIPRLTSDTITLNVDGSAAGQ 1862 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F Y ++ED + V + A RL Y+I GN +F G G Sbjct: 1863 LPPRFSKVSYHFMVSEDAKYLSLVGIILARSIS-GARLDYKIVSGNVGDKFIAM---GDG 1918 Query: 422 LITVAQPLDFKQER-RYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASV 478 I + LDF++++ +Y L V AT+ G T V+I++ +AN++ P F+ Y+ + Sbjct: 1919 RILLNSLLDFERDQTQYNLKVKATEQIPDGLDSTVDVKIDVINANDHFPYFDQQLYSVQI 1978 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E +G V V+A D D + + + S E +F I+P TG I+ + Sbjct: 1979 PESTAVGVLVQEVTAKDCDCLSSCTCSPGFLT-YSIEPSKEQGGKFYIDPATGKISVSVA 2037 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LD E +LL V A D G S V +++ +VNDN P F + Y + E A G Sbjct: 2038 LDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAYEFRVAEGAATGE 2097 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 S++ V A DAD + Y K F +D ++GVI N ALD + L+ + Sbjct: 2098 SLAIVVAVDAD---GDAVTYS---KAGGALQFSVDQSTGVITLNSALDPNK-NQYTLQVM 2150 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A D G +STV V + D N++ P F ++C T I EN P T I ++ A D D G Sbjct: 2151 AKDSGG--LTSTVSVTFNVADANNNVPQF-TNCGTVSIRENDPRDTKITQLTATDADRGQ 2207 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 N + YSI+ FS+E R G + ++ LD E+ + Y +I+A D Sbjct: 2208 NGQITYSIEDASSQTLFSIEPRTGVVR----SLTSLDREN-KDSYNAIIKAEDGSSKQDE 2262 Query: 779 RVEIL--------VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQ 828 +L V DVNDN P + + + V A DAD K++ Sbjct: 2263 SERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAPNGSNILTVQATDADSGSNAKIK 2322 Query: 829 YRILSGNNANLILLNETTGSM---TLSPQLNTNVPKLATMEVSVTD 871 Y +L ++A + +++G + T +L K +EVS D Sbjct: 2323 YALL--DSAGGLFRLDSSGILRTNTNPARLQLETGKKLLLEVSAKD 2366 Score = 194 bits (474), Expect = 6e-49 Identities = 230/908 (25%), Positives = 386/908 (42%), Gaps = 104/908 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69 +N+ D ND +P F Y S++EG + T +L + A D D G N ++ Y+I Sbjct: 1235 VNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNGKILYSI----LSG 1290 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++P+ F ID +G + T+ +LD E +T+ ++A D SP R Sbjct: 1291 VHPD------------WDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSP--KR 1336 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS A + +++ID NDN P F+ Y + + + ++ ATD D G N I Y Sbjct: 1337 LSGIAQVDIDVIDRNDNSPVFAAAFYRAKIS--LGAVKGTSVLQVHATDLDSGQNGQITY 1394 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +II GN + F+I+ G + + K+L + L + A+D + RS + + IN+ Sbjct: 1395 SIIQGNEEEAFTINE-QGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVY- 1452 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 + D P F S V E VP + + V+A ++ LTYT+ +GN Sbjct: 1453 LPDGPPMFVVSPVTVYVKEGVPANHRVAGVKAATSEA-----LTYTLL----SGNEAGMF 1503 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP- 368 I+P +G + + +LD E + +Y+L + A D D RSA F+ Sbjct: 1504 RINPSTGSLDATRELDYEERRRYELKIEARDTRD--RSAMVELIIIVVNINDNKPTFVDI 1561 Query: 369 --GQYEVELA-----EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 GQ + + D G + L A D D D I + + F I S RG Sbjct: 1562 VDGQIDRKAIGTCSPTDIAEGEVITRLGAFDRDGDEITF--IVPDDVKDLFKIDS---RG 1616 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 ++T +P++ + Y V A D+G V++ + + Y P + +V ED Sbjct: 1617 VVTAKKPIE-DLPKIYPFNVKALDNGEPPQETDVKVRLVFVH-YRP--DQKHVRVNVRED 1672 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P G+ + V + I L E +N +V + ++ P LD Sbjct: 1673 TPTGSVIATVRRYFPN-----GIVSLLLPEKANFSVRANGDVILLTP----------LDY 1717 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E+ + +TV G + ++ DVE+ V+DVNDN P++ ++ A + ++ G V Sbjct: 1718 ESQQFHRMTVREELG---NQTNDVDVEVVVLDVNDNRPIWMERERLARVNTNSRAGAQVY 1774 Query: 602 QVGATDADVGLNGRIHYEL-----DPKDRE----EGSFVIDPASGVIRTNKALDRESVAT 652 Q+ A D D G +G + Y+L D K + + F I+P + + +L + Sbjct: 1775 QLEARDEDDGSSGLVGYQLKSPSNDAKRKRRSPPQHPFTINPKTRQMEVAGSLKDQ---R 1831 Query: 653 HDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 +DL A D G P S T+ +++ PP F F +SE++ + +G I A Sbjct: 1832 YDLDVFAFDYGIPRLTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLSLVGIILA 1891 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 A + Y I G+ + F G + L ++ LD+E + +Y L ++A Sbjct: 1892 RSIS---GARLDYKIVSGNVGDKF---IAMGDGRILLNSL--LDFERDQTQYNLKVKATE 1943 Query: 772 ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK- 826 L + V V+I V + ND+ P D Q+ + VG V A D D Sbjct: 1944 QIPDGLDSTVDVKIDVINANDHFPYF-DQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSC 2002 Query: 827 ------LQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878 L Y I S ++ TG +++S L+ + ++V TD G + Sbjct: 2003 TCSPGFLTYSIEPSKEQGGKFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQG 2062 Query: 879 MMQLSVRL 886 + ++V L Sbjct: 2063 LCFVNVTL 2070 Score = 170 bits (413), Expect = 2e-41 Identities = 202/754 (26%), Positives = 327/754 (43%), Gaps = 75/754 (9%) Query: 207 GDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF------- 257 G V+ + ++YE + Y L + + G L I I DVN+ P F Sbjct: 77 GHVTSTQEIEYEIGKTNKYDLTVLQRPRGETLGGIAITLRITILDVNNFHPVFQLSQGEH 136 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDY--TGNVDLPITIDPR 314 Y +E +EN I + + A D D G+ + +K Y V + + R Sbjct: 137 YEGFVKEGTAENT-IVEGLEQCHATDRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSR 195 Query: 315 SGWVY-TSGQ-LDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 V T+G+ + R+ Y +L V TDGG+P S TA F QY Sbjct: 196 KFLVLKTTGKPIVRDDNNPYIMLTVQVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQY 255 Query: 372 EVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 +AE+ P T V+ + ATD D+ N Y F+I + G+I VA+ LD Sbjct: 256 RETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMKNPVNSYFTIDAIT--GVIRVAKTLD 313 Query: 431 FKQERRYVLTVSATDSGG---RSDTAMVQINITD-------------ANNYAPVFENAPY 474 + ++ L +SA D G S A V+I++ + N P F + Y Sbjct: 314 YNARDKHTLYISARDRGDPPRTSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRY 373 Query: 475 TASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 T S+ ED P +LV+ A D+D +G N ++ YSLS + +F I+P++G + Sbjct: 374 TFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSLS--------GNGVSKFAIDPESGVV 425 Query: 534 TTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588 T +D E Y LTVTA D G SLS TT +EI VD N N P F Q Sbjct: 426 TLTDSVDYENTPNNHVYDLTVTATDQGPGSLSATTQLLIEIQDVDENKNSPRFDPQQAIL 485 Query: 589 NIMEDALVGTSVSQVGATDAD-VG----LNGRIHYELDPKDREEGSFVIDPASGVIRTN- 642 I E+ + V+ V ATD+D VG +G++ Y + G F +D +G ++ Sbjct: 486 EISENLKQNSLVTTVSATDSDSVGNPSSPDGKVVYSI-VGGTGLGVFRVDSNTGEVKVAV 544 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 +LDRE + + L A D T P+SS + + I + D +D+ P F + EN P Sbjct: 545 PSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPS 604 Query: 703 GTTIGEIRAHDPDEGPN---AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 GT + + D DEG N V+ + + ++ + T + D++EL T Sbjct: 605 GTFVTVVVGRDADEGFNPSYTVITPGVPYKIEPSTGVIRTSKSLDQSELST--------- 655 Query: 760 RKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 ++ ++++R ++ D +V I V + PV K+ ++ P+ + A Sbjct: 656 -RELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAA 714 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK 877 D+ ++ +QY + G + L +++ +G + N NV + + T V E+ Sbjct: 715 VDS-LSRPVQYTLAPGAD-GLFEVDKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEV- 771 Query: 878 AMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911 A L+V +TEE L + +T ++ +P Sbjct: 772 ASASLTVE-VTEEKDLPKFSSDSYQLTVDESAAP 804 Score = 169 bits (410), Expect = 4e-41 Identities = 145/509 (28%), Positives = 236/509 (46%), Gaps = 45/509 (8%) Query: 97 GALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 G +L + LD E+ +Y + VKAT+Q + D L ST + +++I+ ND++P F ++ Y Sbjct: 1918 GRILLNSLLDFERDQTQYNLKVKATEQ---IPDGLDSTVDVKIDVINANDHFPYFDQQLY 1974 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSA-----IRYAIIGGNTQM-QFSIDSLSGDV 209 +V + E +V ++ ++ A D D ++ + Y+I Q +F ID +G + Sbjct: 1975 SVQIPESTAV--GVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQGGKFYIDPATGKI 2032 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 S+ LDYE R + L + A D G S + + + +VNDN P F S ++ V+E Sbjct: 2033 SVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAYEFRVAEG 2092 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 G S+ V A DAD +TY+ G L ++D +G + + LD + Sbjct: 2093 AATGESLAIVVAVDAD---GDAVTYSK-----AGGA-LQFSVDQSTGVITLNSALD-PNK 2142 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 +Y L V A D G + + T V + E++P T + LT Sbjct: 2143 NQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQ---FTNCGTVSIRENDPRDTKITQLT 2199 Query: 390 ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 ATDAD ++ ++ Y I +++ FSI + G++ LD + + Y + A D Sbjct: 2200 ATDADRGQNGQITYSIEDASSQTLFSIEPRT--GVVRSLTSLDRENKDSYNAIIKAEDGS 2257 Query: 448 GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 + D + + IN+ D N+ P F A Y SVF AP G+ +L V ATD+D G Sbjct: 2258 SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAPNGSNILTVQATDADSGS 2317 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVI----NPQTGAITTNKLLDRETMSGYLLTVTARDG 556 NA+I Y+L S + D ++ NP + T K L E + + ++ Sbjct: 2318 NAKIKYALLD--SAGGLFRLDSSGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQP 2375 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 G P+ TT +EI V N+ P F QQ+ Sbjct: 2376 GKPT-KYTTQIEILV--SNEEPPKFSQQV 2401 Score = 122 bits (293), Expect = 5e-27 Identities = 141/585 (24%), Positives = 242/585 (41%), Gaps = 64/585 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+LD +D+ P F Y A V E SGT V + D D G N YT+ +T Sbjct: 577 INLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPS--YTV--ITPGV- 631 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSD 128 ++I+ +G + T SLD+ +++ V+V+ + S +D Sbjct: 632 ------------------PYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTAD 673 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 +++ +I + P F Y+V V E++ N + I A D+ + ++ Sbjct: 674 -----GQVNITVISKVNRPPVFKNTPYSVKVPEEMGPLPN--LFCIAAVDS---LSRPVQ 723 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + G + F +D SG + + +YE V Y L I A+ S + L + + Sbjct: 724 YTLAPGADGL-FEVDKDSGRLHTKNSFNYENVDRYNLRIEARTS-SVQEVASASLTVEVT 781 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 + D P+F + +Q +V E+ G ++ D +++ + + + Sbjct: 782 EEKD-LPKFSSDSYQLTVDESAAPGTTLAPGLLI-IDSDTSSDQFDCSMEAITSLHTLYN 839 Query: 309 ITIDPRSGW----VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + +SG V G+LD +KY V ATD ATA Sbjct: 840 FEVTQQSGRCFLRVQAGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKP 899 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422 F+ Y + + P G+ +VT+ A D D + ++ YE+ RF + N Sbjct: 900 EFLQESYWLSVPSSTPAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFILNDNNQLST 959 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVF 479 + P RY L + A+DS R+ ++ V +++ + VF+ + Y ++ Sbjct: 960 ASTLTP-----NVRYQLLIRASDSATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLP 1014 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED+ T V AT S ++ +S + EA+ F I P TG + K L Sbjct: 1015 EDSSANTLVFTAKATRSGSSRGSRT----NSSVIGEAM------FSIKPDTGQVYLIKKL 1064 Query: 540 DRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 D ET S + + V A+ GG L+ ++++VDVNDN P + Q Sbjct: 1065 DFETKSYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRYTQ 1109 >SB_56770| Best HMM Match : Cadherin (HMM E-Value=0) Length = 1136 Score = 216 bits (528), Expect = 2e-55 Identities = 187/717 (26%), Positives = 324/717 (45%), Gaps = 42/717 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 +F ID S + A+LD EK L V ATDQ SP S+ +++ +D+N N Sbjct: 396 LFAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSA-SAPLIVYIKDVDENQNL 454 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F K +SV ED ++ + I KATD D G + + Y+++ G ++ +G Sbjct: 455 PVFDPKAQAISVKEDTALGTS--IFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTG 512 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 V+ D + +VI A D G+ R++ LLI + V+D P F + +V Sbjct: 513 VVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFTQPAYSATVL 572 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 + P +V + A D + N ++ Y + + G DL ++ +G + T+ + + Sbjct: 573 DGSPENTFVVALHATDYE---NTQIEYRLVN---VGVNDL-FQVERSTGVIRTARE-PAK 624 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 T+ + + D R A F +E+++ E+ P +V Sbjct: 625 TRGDQEFNQLIIEASDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDSLVC 684 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 L ATD D + + Y ITGG G+F++ +G+ +V + D++ E Y++ V A Sbjct: 685 LAATDGDLGS-ITYSITGGGN-GKFAVDQHSGK--FSVLRSFDYELENGYIVQVQAETPN 740 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA----TDSDVGINAQ 503 ++ +A V++ I++ ++ P F YT +V E GTT+L S+ D D Q Sbjct: 741 AKTSSANVKLIISNIDDL-PSFAKPEYTLTVPEGTTPGTTILDGSSGFQFVDDDTNPE-Q 798 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 SL E+++ V H + + + L + +++ + V + P++ Sbjct: 799 FECSLM-EVTSMFVLEHFRVERSDSECRLTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQA 857 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYEL-- 620 T V++S+ DVN++ P Q Y A + D T + V A+D D N ++ ++ Sbjct: 858 TAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVS 917 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 D + F ID ++G I + L + + L A D G+PP S V V + + Sbjct: 918 DADSSGQNRFQIDSSTGTITSTNLLAANN--EYKLTVKATDTGSPPMESQVSVTVSVITP 975 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 +P F I E+ IG ++ ++ A P A + YSI GG+ +++F ++ Sbjct: 976 ITTPVKFAEANYAKTIQESLVIGNSVLQVTATGP-----AAITYSIVGGNKNDAFRIDRT 1030 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAA----SPPLWNDVRVEILVTDVNDNAPV 793 G ++ LDYE + Y L +RA +P + +V V I +TDVNDN+PV Sbjct: 1031 TG----QIAVNKPLDYEV-LQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPV 1082 Score = 207 bits (506), Expect = 9e-53 Identities = 186/688 (27%), Positives = 316/688 (45%), Gaps = 63/688 (9%) Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSAIRY 189 + T+ V I D N+ P F Y +V E S D V + A D D G S+ Y Sbjct: 103 TATTLLVTIKDSNNFLPTFGSSVYNGTVMEG-SKEDTVVKGLENCHAEDRDTGGISS--Y 159 Query: 190 AIIGGNTQMQFSIDSLS-GDVSLVKTLDYE------QVRSYRLVIRAQDGGSPSRSNTTQ 242 II GN + F +++ G+ ++ L + + +LV+ A+D GSP+R+ TTQ Sbjct: 160 TIISGNEKGYFKTSTINVGEERFLQILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQ 219 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + I++ + N+N P+F + V E + + RV A D D+G++ + Y Y Sbjct: 220 IHISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYY------YL 273 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT------------A 350 + T++P +G V G LD + Q+ YQL V ATD G P R A + Sbjct: 274 SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTIKDSQFS 333 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407 F + ED P V TATD D + RL Y ++G Sbjct: 334 PPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLYSLSGPE 393 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSGGRSDTA----MVQINITDA 462 G F+I + ++T+A LD+++ + LTV+ATD G + +A +V I D Sbjct: 394 A-GLFAIDPDS--AVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDE 450 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N PVF+ SV ED +GT++ ATD D G + ++ YS+ ++ E V + Sbjct: 451 NQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSM---VAGEGVGY--- 504 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 ++N TG +TT + DR+T + + A D G + + I V V+D P F Sbjct: 505 -VILNETTGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFT 563 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Q Y+A +++ + T V + ATD + N +I Y L + F ++ ++GVIRT Sbjct: 564 QPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVND-LFQVERSTGVIRTA 619 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 + ++ + + I+ + + +V+I I+ + P F + + ENS Sbjct: 620 RE-PAKTRGDQEFNQLIIEASDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGP 678 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 ++ + A D D G + YSI GG + F+++ Q S K ++ D + E+ Sbjct: 679 FDSLVCLAATDGDLGS---ITYSITGG-GNGKFAVD--QHSGKFSVLRSFDYELEN---G 729 Query: 763 YELVIRAASP-PLWNDVRVEILVTDVND 789 Y + ++A +P + V++++++++D Sbjct: 730 YIVQVQAETPNAKTSSANVKLIISNIDD 757 Score = 183 bits (446), Expect = 2e-45 Identities = 228/937 (24%), Positives = 390/937 (41%), Gaps = 97/937 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V + N+++P FE ++Y A V E + V + A D D G + V Y L Sbjct: 222 ISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYYY--------L 273 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P + F ++ +G ++ +LD +K + Y + V ATD+ SP + Sbjct: 274 SP-------------LSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAA 320 Query: 131 SSTA-TIH-------VNIIDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + TI + D N P F+ K +V ED+ N + ATD D Sbjct: 321 TKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVREDLP--KNGFVFLATATDNDP 378 Query: 182 -GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY-RLVIRAQDGGSPSRSN 239 G N + Y++ G + F+ID S V+L LDYE+ + L + A D GSP+ S Sbjct: 379 PGPNQRLLYSLSGPEAGL-FAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSA 437 Query: 240 TTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + L++ I+DV N N P F SV E+ +G SI +A D D G + EL Y+M Sbjct: 438 SAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMV 497 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 + G V L T +G V T+ DR+T ++++ A D G PR++ Sbjct: 498 AGEGVGYVILNET----TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVE 553 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417 F Y + + P T VV L ATD E+ ++ Y + F + Sbjct: 554 KVDDMYPEFTQPAYSATVLDGSPENTFVVALHATDY-ENTQIEYRLVNVGVNDLFQVERS 612 Query: 418 NGRGLITVAQPLDFKQERRY-VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 G + T +P + ++ + L + A+D ++ T +V I I P F + + Sbjct: 613 TGV-IRTAREPAKTRGDQEFNQLIIEASDKTRQAIT-LVNILIKSTKEVVPRFTTSAFEI 670 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V E++ +++ ++ATD D+G ITYS++ + + F ++ +G + Sbjct: 671 KVPENSGPFDSLVCLAATDGDLG---SITYSITGGGNGK--------FAVDQHSGKFSVL 719 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + D E +GY++ V A + S + IS +D + P F + YT + E Sbjct: 720 RSFDYELENGYIVQVQAETPNAKTSSANVKLIISNID---DLPSFAKPEYTLTVPEGTTP 776 Query: 597 GTSV--SQVGATDADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTN--KAL-DR 647 GT++ G D N +E + F ++ + R K+L + Sbjct: 777 GTTILDGSSGFQFVDDDTNPE-QFECSLMEVTSMFVLEHFRVERSDSECRLTVIKSLFEH 835 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 SV + P +T V + I+D+N+ P +S ++P T I Sbjct: 836 HSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIV 895 Query: 708 EIRAHDPD--EGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + A D D EG V+ + D S N F +++ G T+ + + +Y Sbjct: 896 TVTASDLDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTG-------TITSTNLLAANNEY 948 Query: 764 ELVIRAA---SPPLWNDVRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 +L ++A SPP+ + V V + ++T + PV ++ +G V Sbjct: 949 KLTVKATDTGSPPMESQVSVTVSVITPIT--TPVKFAEANYAKTIQESLVIG--NSVLQV 1004 Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879 A + Y I+ GN + ++ TTG + ++ L+ V + + V T K Sbjct: 1005 TATGPAAITYSIVGGNKNDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIA 1064 Query: 880 MQLSVRLITEEM-------LL--NSITVRLNDMTAEQ 907 +++V + ++ LL N TV +N T EQ Sbjct: 1065 AEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQ 1101 Score = 176 bits (428), Expect = 2e-43 Identities = 225/918 (24%), Positives = 383/918 (41%), Gaps = 92/918 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIELVTA 67 + + D N+ P F Y +V EG+ T V L+ A D+D G + YTI ++ Sbjct: 109 VTIKDSNNFLPTFGSSVYNGTVMEGSKEDTVVKGLENCHAEDRDTGGISS--YTI--ISG 164 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 + E + +I L T + R+ ++V+A D SP Sbjct: 165 N----EKGYFKTSTINVGEERFLQI------LTTDLPITRDTTNTIKLVVEARDSGSPAR 214 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + T IH+++ + N+N P+F ++ YT V E+ + N +A++ A D D G + ++ Sbjct: 215 ---TVTTQIHISVENRNENTPKFEKEEYTAMVMEETQL--NSPVARVHAKDTDQGMSGSV 269 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y + F+++ ++G V LV TLDY++ SY+L + A D GSP R T++++ I Sbjct: 270 YYYL--SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTI 327 Query: 248 RDVN------------DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTY 294 +D + AP F +V E++P + A D D G N L Y Sbjct: 328 KDSQFSPPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLY 387 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXX 353 +++ + G IDP S V + LD E L VTATD G P SA+A Sbjct: 388 SLSGPE-AG----LFAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLI 442 Query: 354 XXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409 F P + + ED GT + T ATD D D L Y + G Sbjct: 443 VYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMVAGEGV 502 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467 G + I ++ G++T A D K + ++A D G R+ + I + ++ P Sbjct: 503 G-YVILNET-TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYP 560 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 F Y+A+V + +P T V+ + ATD + N QI Y L + N+ F + Sbjct: 561 EFTQPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVNDL-------FQVE 610 Query: 528 PQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 TG I T + R L + A D + T V I + + P F Sbjct: 611 RSTGVIRTAREPAKTRGDQEFNQLIIEASD---KTRQAITLVNILIKSTKEVVPRFTTSA 667 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 + + E++ S+ + ATD D+ G I Y + G F +D SG ++ Sbjct: 668 FEIKVPENSGPFDSLVCLAATDGDL---GSITYSI--TGGGNGKFAVDQHSGKFSVLRSF 722 Query: 646 DRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 D E + V + TP ++S+ V + I +I+D P F T + E + GT Sbjct: 723 DYE---LENGYIVQVQAETPNAKTSSANVKLIISNIDDLPS-FAKPEYTLTVPEGTTPGT 778 Query: 705 TI--GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE---TRQGSDKAELVTMVDLDYESP 759 TI G D+ N + + ++ F LE + + L + L Sbjct: 779 TILDGSSGFQFVDDDTNP-EQFECSLMEVTSMFVLEHFRVERSDSECRLTVIKSLFEHHS 837 Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816 ++ +++ A P + +V++ + DVN++AP + D P V Sbjct: 838 VTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTV 897 Query: 817 PAYDADVTD---KLQYRILS---GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 A D D + ++ ++ +S + N ++ +TG++T + L N T++ + T Sbjct: 898 TASDLDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTGTITSTNLLAANNEYKLTVKATDT 957 Query: 871 DGVNEIKAMMQLSVRLIT 888 G +++ + ++V +IT Sbjct: 958 -GSPPMESQVSVTVSVIT 974 Score = 172 bits (419), Expect = 3e-42 Identities = 187/729 (25%), Positives = 315/729 (43%), Gaps = 78/729 (10%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S P ++ I +D N + PVF+ + SV+E + GT++ T KATD+D G + E+EY+ Sbjct: 438 SAPLIVY--IKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYS 495 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 +V + + ++ +G + T A DR+ V++ A D Sbjct: 496 --MVAGEGVG-----------------YVILNETTGVVTTAAMFDRKTNPVVEVVIAAHD 536 Query: 122 QAS-PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 + + P + + I V +DD YP+F++ Y+ +V + +N + + ATD + Sbjct: 537 KGTFPRTSKFY--LLIQVEKVDDM--YPEFTQPAYSATVLD--GSPENTFVVALHATDYE 590 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV----KTLDYEQVRSYRLVIRAQDGGSPS 236 N+ I Y ++ F ++ +G + KT ++ +L+I A D + Sbjct: 591 ---NTQIEYRLVNVGVNDLFQVERSTGVIRTAREPAKTRGDQEFN--QLIIEASD---KT 642 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 R T + I I+ + PRF TS F+ V EN S+V + A D D G +TY++ Sbjct: 643 RQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDSLVCLAATDGDLG---SITYSI 699 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 T G + +D SG D E + Y + V A P ++ Sbjct: 700 T-----GGGNGKFAVDQHSGKFSVLRSFDYELENGYIVQVQAET---PNAKTSSANVKLI 751 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA--------TDADEDNRLHYEITGGNT 408 F +Y + + E PGT ++ ++ T+ ++ E+T Sbjct: 752 ISNIDDLPSFAKPEYTLTVPEGTTPGTTILDGSSGFQFVDDDTNPEQFECSLMEVTSMFV 811 Query: 409 RGRFSITSQNGRGLITVAQPL-DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465 F + + +TV + L + ++ V T+ TA V ++I D NN+ Sbjct: 812 LEHFRVERSDSECRLTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNH 871 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQF 524 AP A Y A+V D P T ++ V+A+D D N Q+ + S+ + +F Sbjct: 872 APEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSDADSSG----QNRF 927 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 I+ TG IT+ LL + Y LTV A D G P + V +SV+ F + Sbjct: 928 QIDSSTGTITSTNLLAAN--NEYKLTVKATDTGSPPMESQVSVTVSVITPITTPVKFAEA 985 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 Y I E ++G SV QV AT I Y + ++ + +F ID +G I NK Sbjct: 986 NYAKTIQESLVIGNSVLQVTATGP-----AAITYSIVGGNKND-AFRIDRTTGQIAVNKP 1039 Query: 645 LDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTFYISENSP 701 LD E + ++ L A + TP ++ V V I + D+ND+ PVF S+ T ++ +P Sbjct: 1040 LDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTP 1099 Query: 702 IGTTIGEIR 710 T + + R Sbjct: 1100 EQTVVFKAR 1108 Score = 147 bits (357), Expect = 1e-34 Identities = 128/481 (26%), Positives = 220/481 (45%), Gaps = 43/481 (8%) Query: 421 GLITVAQPLDFK--QERRYVLT-VSATDSGGRSDTAM-VQINITDANNYAPVFENAPYTA 476 G++T A+P +++ + + LT V S G TA + + I D+NN+ P F ++ Y Sbjct: 69 GVVTSAKPFEYRIGESNTFTLTIVKRQRSQGFGGTATTLLVTIKDSNNFLPTFGSSVYNG 128 Query: 477 SVFEDAPIGTTVLVVS---ATDSDVGINAQITYSLSSE---ISNEAVAHHDQQFVINPQT 530 +V E + T V + A D D G + T +E + +++F+ Sbjct: 129 TVMEGSKEDTVVKGLENCHAEDRDTGGISSYTIISGNEKGYFKTSTINVGEERFL----- 183 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 +TT+ + R+T + L V ARD G P+ + TT + ISV + N+N P F+++ YTA + Sbjct: 184 QILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTAMV 243 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 ME+ + + V++V A D D G++G ++Y L P F ++P +GV+ LD + Sbjct: 244 MEETQLNSPVARVHAKDTDQGMSGSVYYYLSPL---SSYFTVNPITGVVILVGTLDYQKQ 300 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP------------PVFESDCLTFYISE 698 +++ L +A D G+P + + V + I+D SP PVF L + E Sbjct: 301 SSYQLTVMATDRGSPRREAATKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVRE 360 Query: 699 NSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 + P + A D D GPN + YS+ G ++ F+++ D A + LDYE Sbjct: 361 DLPKNGFVFLATATDNDPPGPNQRLLYSL-SGPEAGLFAID----PDSAVVTLAAALDYE 415 Query: 758 SPRKKYELVIRA---ASPPLWNDVRVEILVTDV--NDNAPVM-KDFQIIFNNYKDCFPVG 811 L + A SP L + + + DV N N PV Q I Sbjct: 416 KGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTS 475 Query: 812 PF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 F + D+ +L+Y +++G ++LNETTG +T + + + + ++ Sbjct: 476 IFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTGVVTTAAMFDRKTNPVVEVVIAAH 535 Query: 871 D 871 D Sbjct: 536 D 536 >SB_35949| Best HMM Match : Cadherin (HMM E-Value=0) Length = 521 Score = 214 bits (522), Expect = 1e-54 Identities = 166/525 (31%), Positives = 245/525 (46%), Gaps = 28/525 (5%) Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 + ++ ATDAD G N+ I Y IIGGN FSIDS +G +S + +LD+E + L+I A+ Sbjct: 9 LLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAK 68 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 DGG+ + T + + + + DN P F ++ +V ENVP G + RV A D+ N Sbjct: 69 DGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDK--NG 126 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 ++Y + D T N+ L +D G + +G +DRE +A+Y L V A G P SA A Sbjct: 127 SISYAIVSGDPT-NLFL---VDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQA 182 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNT 408 T F V++ G V A D D ++ + Y++T N Sbjct: 183 TVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLT-SNA 241 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 G I S + G+I +A+ L E +Y + V A+DSG + + I+IT + N+ P Sbjct: 242 EGLLWINSTS--GVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLSINHPPK 299 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F + Y V P+ V A D D G N Q+ YS+ NE + F I P Sbjct: 300 FTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ--GNE-----EGLFGIFP 352 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 G + K L + Y L V A DGGVPS S + V I + D ND+ +F + Sbjct: 353 -GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRF 411 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + E++ GT V + A D I Y L E F +D SG I T LDRE Sbjct: 412 AVAENSSPGTLVGTLVAHALDHSRTKDIVYSL---ISSESHFAVDVRSGQITTRVRLDRE 468 Query: 649 SVA------THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 + + ++A A+ T + IV + + D+ND+ PVF Sbjct: 469 ELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVF 513 Score = 196 bits (477), Expect = 3e-49 Identities = 155/536 (28%), Positives = 246/536 (45%), Gaps = 35/536 (6%) Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN P G +++V A DADEG NA ++Y + + GN +ID +G + T LD E Sbjct: 2 ENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGN----FSIDSSTGVISTLASLDHE 56 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 + + L+++A DGG+ + TA F+ Y + E+ P GT V Sbjct: 57 VEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGR 116 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 + AT D++ + Y I G+ F + S G +I + +D +++ +Y+L V A Sbjct: 117 VYATTKDKNGSISYAIVSGDPTNLFLVDSTGG--IIKINGDMDREEKAQYLLAVIARVGT 174 Query: 448 GR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 + S A V I + D N+ AP F + + +G V +A D D G N + Sbjct: 175 VKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVR 234 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 Y L+S IN +G I + L + Y + V A D G P T Sbjct: 235 YQLTSNAEG--------LLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTM 286 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 + I++ +N + P F Y +++ + V A D D G NG++ Y + P+ Sbjct: 287 TIHITL-SIN-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSI-PQGN 343 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 EEG F I P G + K+L + ++DL A DGG P S++V V I I+D ND Sbjct: 344 EEGLFGIFPG-GKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRS 402 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 +F ++ F ++ENS GT +G + AH D + YS+ + + F+++ R G Sbjct: 403 LFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSE--SHFAVDVRSG--- 457 Query: 746 AELVTMVDLDYESPRKKY-ELVIRAASPPLWNDVRVE-------ILVTDVNDNAPV 793 ++ T V LD E K V + ++ND ++ + VTD+NDNAPV Sbjct: 458 -QITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPV 512 Score = 171 bits (416), Expect = 7e-42 Identities = 142/507 (28%), Positives = 230/507 (45%), Gaps = 36/507 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G + T ASLD E +++++ A D + + + TA ++V +++ DN P Sbjct: 38 FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYA---AKTAVVNVTVLNKADNLPV 94 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F + Y +V E+ V ++ ++ AT D N +I YAI+ G+ F +DS G + Sbjct: 95 FLYEMYNFTVYEN--VPKGTLVGRVYATTKD--KNGSISYAIVSGDPTNLFLVDSTGGII 150 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + +D E+ Y L + A+ G S + I + D NDNAP+F TS + Sbjct: 151 KINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGT 210 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 +G + A D D G N + Y +T N + + I+ SG + + +L + Sbjct: 211 WLVGQVVYNAAAVDLDAGKNGLVRYQLTS-----NAEGLLWINSTSGVIKLARKLTDGDE 265 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 +Y + V A+D G PP+ +T T F Y + +P + Sbjct: 266 TQYTVQVLASDSGSPPQHSTMTIHITLSINHPPK--FTLSSYVTHVLASQPLSYQFFYVV 323 Query: 390 ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 A D D ++ +L Y I GN G F I G + + + L + Y L V ATD G Sbjct: 324 AVDQDSGKNGQLFYSIPQGNEEGLFGIFPG---GKLYIRKSLLQALKGSYDLIVRATDGG 380 Query: 448 GRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 S +A V + I D+N++ +F N + +V E++ GT V + A D I Sbjct: 381 VPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIV 440 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM------SGYLLTVTARDGGVP 559 YSL IS+E+ F ++ ++G ITT LDRE + + Y++ A Sbjct: 441 YSL---ISSES------HFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTT 491 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLY 586 D V ++V D+NDN PVF + +Y Sbjct: 492 IKRDKAIVIVTVTDLNDNAPVFSRAVY 518 Score = 161 bits (391), Expect = 7e-39 Identities = 138/472 (29%), Positives = 213/472 (45%), Gaps = 44/472 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VL+ D+ PVF + Y +V E GT V + AT +D KN + Y I V+ D Sbjct: 83 VTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKD--KNGSISYAI--VSGDPT 138 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +F +D G + +DRE+ A+Y + V A + V L Sbjct: 139 N-----------------LFLVDSTGGIIKINGDMDREEKAQYLLAVIA--RVGTVKP-L 178 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ AT+++ ++D NDN PQFS T +V VD D + V+ A D D G N +RY Sbjct: 179 SAQATVNIEVLDRNDNAPQFS--TSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQ 236 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + N + I+S SG + L + L Y + + A D GSP + +T + I + + Sbjct: 237 LT-SNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL-SI 294 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N + P+F S + V + P+ Y V A D D G N +L Y++ GN + Sbjct: 295 N-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ----GNEEGLFG 349 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I P G +Y L + + Y L+V ATDGG P SA+ F+ Sbjct: 350 IFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNT 408 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + +AE+ PGT V TL A D + ++ F++ ++G+ IT LD Sbjct: 409 FRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQ--ITTRVRLD 466 Query: 431 FKQ------ERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPY 474 ++ Y++ A D+ + D A+V + +TD N+ APVF A Y Sbjct: 467 REELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVY 518 Score = 66.9 bits (156), Expect = 2e-10 Identities = 50/163 (30%), Positives = 82/163 (50%), Gaps = 11/163 (6%) Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 EN P G + ++ A D DEG NAV+ Y I GG+++ +FS+++ G + T+ LD+E Sbjct: 2 ENEPPGKLL-QVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGV----ISTLASLDHE 56 Query: 758 SPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF- 813 + + L+I A + V + V + DN PV F Y++ P G Sbjct: 57 V-EEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENV-PKGTLV 114 Query: 814 GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 GRV A D + Y I+SG+ NL L++ T G + ++ ++ Sbjct: 115 GRVYATTKDKNGSISYAIVSGDPTNLFLVDSTGGIIKINGDMD 157 Score = 48.4 bits (110), Expect = 8e-05 Identities = 45/160 (28%), Positives = 71/160 (44%), Gaps = 28/160 (17%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 SVP I+ Q D NDH +F + +V E +S GT V TL A D + ++ Y+ Sbjct: 387 SVPVTIYIQ----DSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYS 442 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVK 118 L+++++ F +D RSG + TR LDRE++ + T V + Sbjct: 443 --LISSESH-------------------FAVDVRSGQITTRVRLDREELIKNTGSNVYIM 481 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 + + A + V + D NDN P FS Y ++ Sbjct: 482 QAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAIT 521 Score = 34.3 bits (75), Expect = 1.4 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Query: 809 PVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866 P G +V A DAD + Y I+ GNN ++ +TG ++ L+ V + ++ Sbjct: 5 PPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLI 64 Query: 867 VSVTDGVNEIKA 878 +S DG N+ A Sbjct: 65 ISAKDGGNKYAA 76 >SB_50345| Best HMM Match : Cadherin (HMM E-Value=0) Length = 1021 Score = 202 bits (492), Expect = 4e-51 Identities = 195/731 (26%), Positives = 331/731 (45%), Gaps = 69/731 (9%) Query: 89 VFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSDRLSSTATIHVNIID 142 +F I+ +G L T+ L+REK+ + + +K T VS +T V ++D Sbjct: 64 IFEINAATGVLRTKILLNREKLPPSAQGDIFQIQIKVTTDTGGVS----ATIPTEVRVLD 119 Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202 ND+ P+F + + + E S + +A DAD+G NS Y I+ GN FS+ Sbjct: 120 INDHSPKFPQDFEELQISE--SAPERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSL 177 Query: 203 D--SLSGDVSLV-----KTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNA 254 S D+ V K LD E Y+LVI A DGG P RS ++ I I D ND++ Sbjct: 178 SLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHS 237 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P F + SV EN P G ++RV A D D G N E+ + + + G +D Sbjct: 238 PEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDESPERG----LFRMDEY 293 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 +G ++T+ LD E +++Y+L V A D G A +V Sbjct: 294 TGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKVEDKNDNAPTIQVKLLQVP 353 Query: 375 LA-------EDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS-QNGRGLIT 424 A ED G+ V + D D ++ ++T + + F++ N + Sbjct: 354 NAARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLLHHKHDFALRRIFNTFYNLE 413 Query: 425 VAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 V +PL+ ++ Y + A D G ++ +++ ++I D N + P + ++ ++ Sbjct: 414 VQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLI-LHIEDKNRHTPTYPIPSRDITIIDN 472 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEI---SNEAVAHHDQQFVINPQTGAITTNKL 538 T V V A D D + Y+++S + N V + F+ ++G + Sbjct: 473 TQPATIVSVFKAEDPDTDREGDLDYTITSLVMGEKNVTVDDPGRYFMYGQKSGELVVIPK 532 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 L + LT+ A+D G + ++V K Q Y +I+E++ +GT Sbjct: 533 LWCAFTPSFRLTLQAKDNGRERKHGEMTLHVTV-------KCAKYQ-YNFSIVENSPLGT 584 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V ++ G + + + R++ F+I+ A+GVIRT + LDRE+VA +DL + Sbjct: 585 IVGRIVVNTRAPG--KVVSFSVITTGRQD--FMINNATGVIRTTRRLDREAVAAYDLVVL 640 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPDE 716 DG + +++ + + D+ND+ PVF +D + N+ G + IRA DPD Sbjct: 641 VTDGDVEMRLASI---VNVVDVNDNAPVFIGLNDNDVMEVPSNAKRGDEVVTIRATDPDS 697 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773 G N + YS+ G+D +F L+ D+ ELV + + ++S Y L I+A+ +PP Sbjct: 698 GLNGKIQYSLIAGNDDKTFILD----KDRGELV-VFNYMFQS---SYVLTIKASDSGNPP 749 Query: 774 LWNDVRVEILV 784 + VR+ I V Sbjct: 750 SESLVRIRIRV 760 Score = 187 bits (456), Expect = 1e-46 Identities = 185/692 (26%), Positives = 286/692 (41%), Gaps = 63/692 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ VLD NDHSP F E + E A + +A D DIG N+ EY I Sbjct: 111 IPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRGN 170 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D L D+ + L+ LDRE Y +++ A D P+ Sbjct: 171 EDGL-------FSLSLKRFSPDMIYV-----YLVNTKRLDRETRDFYQLVIVAVDGGFPL 218 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S +++ I+D ND+ P+FS+ YT SV E+ + + ++ A D D+G N Sbjct: 219 PR--SGRKEVNITILDSNDHSPEFSKDFYTASVPEN--APNGTYLLRVTAIDQDIGKNGE 274 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I + + + F +D +G++ LDYE YRL + AQD G S Q+ I Sbjct: 275 IMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIK 334 Query: 247 IRDVNDNAPRFYTSLFQES-------VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + D NDNAP L Q V E++ G ++ V+ D D + +T Sbjct: 335 VEDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLL 394 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + + L + + L+ Q+ Y++ A D G P + Sbjct: 395 HHKHDFALRRIFNTFYN-LEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLILHIEDK 453 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITG---GNTR----- 409 + ++ + ++ P T V A D D D L Y IT G Sbjct: 454 NRHTPTYPIPSRDITIIDNTQPATIVSVFKAEDPDTDREGDLDYTITSLVMGEKNVTVDD 513 Query: 410 -GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 GR+ + Q G + V L + LT+ A D+G + +++T Sbjct: 514 PGRYFMYGQKS-GELVVIPKLWCAFTPSFRLTLQAKDNGRERKHGEMTLHVT------VK 566 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 Y S+ E++P+GT V + +N T + +S + Q F+IN Sbjct: 567 CAKYQYNFSIVENSPLGTIV-------GRIVVN---TRAPGKVVSFSVITTGRQDFMINN 616 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 TG I T + LDRE ++ Y L V DG V + ++VVDVNDN PVF L Sbjct: 617 ATGVIRTTRRLDREAVAAYDLVVLVTDGDVEMRLASI---VNVVDVNDNAPVF-IGLNDN 672 Query: 589 NIME---DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 ++ME +A G V + ATD D GLNG+I Y L ++ +F++D G + + Sbjct: 673 DVMEVPSNAKRGDEVVTIRATDPDSGLNGKIQYSL-IAGNDDKTFILDKDRGELVVFNYM 731 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 + S + L A D G PP S V + I++ Sbjct: 732 FQSS---YVLTIKASDSGNPPSESLVRIRIRV 760 Score = 155 bits (377), Expect = 4e-37 Identities = 149/578 (25%), Positives = 239/578 (41%), Gaps = 60/578 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I +LD NDHSP F Y ASV E A +GT +L + A DQDIGKN E+ + ++ Sbjct: 228 ITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDE------ 281 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +PE + +FR+D +G + T A LD E + Y + V A DQ D + Sbjct: 282 SPE-------------RGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGP---DSI 325 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVS-------VDEDISVTDNPVIAKIKATDADVGA 183 A + + + D NDN P K V V EDI+ N I +++ D+ + Sbjct: 326 PVRAQVTIKVEDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTV 385 Query: 184 NSAIRYAIIGGNTQMQFS-IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 NS + ++ I + ++ + + L+ + Y++ A+D G P+ Sbjct: 386 NSVVDVTLLHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNS 445 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK--- 299 L+++I D N + P + ++ +N + +A D D +L YT+T Sbjct: 446 LILHIEDKNRHTPTYPIPSRDITIIDNTQPATIVSVFKAEDPDTDREGDLDYTITSLVMG 505 Query: 300 DYTGNVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + VD P +SG + +L ++L + A D G + T Sbjct: 506 EKNVTVDDPGRYFMYGQKSGELVVIPKLWCAFTPSFRLTLQAKDNGRERKHGEMTLHVTV 565 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416 QY + E+ P GT V + + + + T GR Sbjct: 566 KCAKY--------QYNFSIVENSPLGTIVGRIVVNTRAPGKVVSFSVI---TTGRQDFMI 614 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE--NAPY 474 N G+I + LD + Y L V TD A + +N+ D N+ APVF N Sbjct: 615 NNATGVIRTTRRLDREAVAAYDLVVLVTDGDVEMRLASI-VNVVDVNDNAPVFIGLNDND 673 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 V +A G V+ + ATD D G+N +I YSL + + D+ F+++ G + Sbjct: 674 VMEVPSNAKRGDEVVTIRATDPDSGLNGKIQYSLIA-------GNDDKTFILDKDRGELV 726 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 + + S Y+LT+ A D G P + I VV Sbjct: 727 VFNYMFQ---SSYVLTIKASDSGNPPSESLVRIRIRVV 761 Score = 147 bits (357), Expect = 1e-34 Identities = 168/695 (24%), Positives = 280/695 (40%), Gaps = 64/695 (9%) Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 D G S + T+ + + D+ND++P+F + +SE+ P +A DAD G N+ Sbjct: 103 DTGGVSATIPTE--VRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNS 160 Query: 291 ELTYTMTDKDYTGNVDLPI-TIDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDP-PR 346 Y + + G L + P +VY + +LDRET+ YQL++ A DGG P PR Sbjct: 161 IQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPR 220 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404 S F Y + E+ P GT ++ +TA D D ++ + + + Sbjct: 221 SGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLD 280 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDA 462 RG F + G I LD++ + Y LTV A D G S A V I + D Sbjct: 281 ESPERGLFRMDEYTGE--IWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKVEDK 338 Query: 463 NNYAPVFE-------NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 N+ AP + NA V ED G+ V +V D D + + + + Sbjct: 339 NDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTV-------NSVVDV 391 Query: 516 AVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 + HH F + + + L+ S Y + ARD GVP+L + + + Sbjct: 392 TLLHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLILHIE 451 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 D N + P + I+++ T VS A D D G + Y + E + + Sbjct: 452 DKNRHTPTYPIPSRDITIIDNTQPATIVSVFKAEDPDTDREGDLDYTITSLVMGEKNVTV 511 Query: 633 D---------PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 D SG + L + L A D G + + +H+ ++ Sbjct: 512 DDPGRYFMYGQKSGELVVIPKLWCAFTPSFRLTLQAKDNGRERKHGEMTLHVTVKCAKYQ 571 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 F I ENSP+GT +G I + P VV +S+ F + G Sbjct: 572 --------YNFSIVENSPLGTIVGRIVVN--TRAPGKVVSFSVI-TTGRQDFMINNATG- 619 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM-----KDFQ 798 + T LD E+ Y+LV+ + + + V DVNDNAPV D Sbjct: 620 ---VIRTTRRLDREAV-AAYDLVVLVTDGDVEMRLASIVNVVDVNDNAPVFIGLNDNDVM 675 Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858 + +N K V R D+ + K+QY +++GN+ +L++ G + + N Sbjct: 676 EVPSNAKRGDEVVTI-RATDPDSGLNGKIQYSLIAGNDDKTFILDKDRGELVV---FNYM 731 Query: 859 VPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEML 892 + + +D N ++++++ +R++ E+L Sbjct: 732 FQSSYVLTIKASDSGNPPSESLVRIRIRVVPPEVL 766 Score = 130 bits (313), Expect = 2e-29 Identities = 100/326 (30%), Positives = 156/326 (47%), Gaps = 13/326 (3%) Query: 374 ELAEDEPPGTPVVTLTATDADEDNRL-----HYEITGGNTRGRFSITSQNG--RGLITVA 426 ++ E++ PG V ++ TD + RL Y+I G G F I + G R I + Sbjct: 23 QVKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGP-ADGIFEINAATGVLRTKILLN 81 Query: 427 Q---PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + P + + + TD+GG S T ++ + D N+++P F + E AP Sbjct: 82 REKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAP 141 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + + A D+D+G N+ Y + + + ++F + + K LDRET Sbjct: 142 ERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRET 201 Query: 544 MSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y L + A DGG P S +V I+++D ND+ P F + YTA++ E+A GT + + Sbjct: 202 RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLR 261 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+G NG I + LD + E G F +D +G I TN LD E + + L VA D Sbjct: 262 VTAIDQDIGKNGEIMFYLD-ESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQ 320 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFE 688 G V IK+ED ND+ P + Sbjct: 321 GPDSIPVRAQVTIKVEDKNDNAPTIQ 346 Score = 87.8 bits (208), Expect = 1e-16 Identities = 97/332 (29%), Positives = 154/332 (46%), Gaps = 27/332 (8%) Query: 590 IMEDALVGTSVSQVGATDADVGLN---GRIHYELD-PKDREEGSFVIDPASGVIRTNKAL 645 + E+ G V V TD L G+I Y++ P D G F I+ A+GV+RT L Sbjct: 24 VKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGPAD---GIFEINAATGVLRTKILL 80 Query: 646 DRESV---ATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 +RE + A D+ + I T S+T+ +++ DIND P F D ISE++ Sbjct: 81 NREKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESA 140 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD---LDYE 757 P + RA D D G N++ Y I G++ FSL ++ S V +V+ LD E Sbjct: 141 PERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRE 200 Query: 758 SPRKKYELVIRAASP--PLWNDVRVEILVT--DVNDNAP-VMKDFQIIFNNYKDCFPVGP 812 + R Y+LVI A PL R E+ +T D ND++P KDF + + P G Sbjct: 201 T-RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTA--SVPENAPNGT 257 Query: 813 F-GRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 + RV A D D+ ++ + + L ++E TG + + L+ V + V Sbjct: 258 YLLRVTAIDQDIGKNGEIMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVA 317 Query: 870 TD-GVNEIKAMMQLSVRLITEEMLLNSITVRL 900 D G + I Q+++++ + +I V+L Sbjct: 318 QDQGPDSIPVRAQVTIKVEDKNDNAPTIQVKL 349 >SB_56686| Best HMM Match : Cadherin (HMM E-Value=0) Length = 1888 Score = 199 bits (486), Expect = 2e-50 Identities = 164/519 (31%), Positives = 242/519 (46%), Gaps = 38/519 (7%) Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LL 244 + YAI GN F +D+ +G V L+ TLDY + SYRLVIRA DGG+ L Sbjct: 3 VSYAIYSGNQAGMFRVDA-NGTVYLLGTLDYARAPSYRLVIRATDGGAKEMRKHADFTLT 61 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D+NDNAP+F + V E IG I + A DAD N +++Y K +GN Sbjct: 62 VLVEDINDNAPKFASDKTMVDVYETSKIGQVITVITATDADASTNGQVSY----KIASGN 117 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDPPRSATATXXXXXXXXX 360 D +D ++G V S LD E L+V ATD G P + A+ Sbjct: 118 DDDYFRLDSKTGHVTLSKSLDLEILHNEGWNRTLVVIATDHGTPRLHSNASFVFRLNSVN 177 Query: 361 XXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417 + + L+ED G+ + L+ATD D D + Y I GN +F + Sbjct: 178 EFPPVWTGNANLSLSLSEDILVGSKIGRLSATDRDYGLDGEIRYIILSGNGERKFHLDEV 237 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENA 472 G+IT+ PLD ++ + L V A+D S R A+V I + D N+ P F+ Sbjct: 238 T--GVITIHAPLDRERTSYFRLRVQASDCSKKASSRRRVYAVVDIKVKDVNDNKPTFQRK 295 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y V E A IG ++ V A+DSD G N ++TYS+ IS + F I+ QTG Sbjct: 296 SYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSI---ISGNDLGF----FGIDSQTGT 348 Query: 533 ITTNKLLDRETMSG-----YLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLY 586 + K LD ET Y+LT++A+D G P +L+ T + I + VN P Sbjct: 349 LRVRKSLDLETQVHVYDLIYILTISAQDQGTPRALNSTAIITIEIRSVNQFTPGLPAPSD 408 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 + E + VG V ATD D G +G I + + E +F ID ++G I K L+ Sbjct: 409 VIH-PESSPVGFEVVDWNATDKDFGADGIIRFAIF-HGNEGNTFDIDSSTGKITVGKKLN 466 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVI--VHIKIEDINDS 683 + L D G Q +++ V +++ ++ND+ Sbjct: 467 FTLYPRYFLHINISDSGPTSQRRSLVTKVTVRVTNLNDN 505 Score = 179 bits (436), Expect = 3e-44 Identities = 151/509 (29%), Positives = 233/509 (45%), Gaps = 38/509 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +FR+D +G + +LD + Y ++++ATD + R + T+ V + D NDN P Sbjct: 15 MFRVDA-NGTVYLLGTLDYARAPSYRLVIRATDGGAKEM-RKHADFTLTVLVEDINDNAP 72 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 +F+ V V E + VI I ATDAD N + Y I GN F +DS +G Sbjct: 73 KFASDKTMVDVYETSKI--GQVITVITATDADASTNGQVSYKIASGNDDDYFRLDSKTGH 130 Query: 209 VSLVKTLDYEQVR----SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY-TSLFQ 263 V+L K+LD E + + LV+ A D G+P + + + VN+ P + + Sbjct: 131 VTLSKSLDLEILHNEGWNRTLVVIATDHGTPRLHSNASFVFRLNSVNEFPPVWTGNANLS 190 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 S+SE++ +G I R+ A D D G++ E+ Y + +GN + +D +G + Sbjct: 191 LSLSEDILVGSKIGRLSATDRDYGLDGEIRYII----LSGNGERKFHLDEVTGVITIHAP 246 Query: 324 LDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 LDRE + ++L V A+D R A F Y V + E Sbjct: 247 LDRERTSYFRLRVQASDCSKKASSRRRVYAVVDIKVKDVNDNKPTFQRKSYYVVVLETAQ 306 Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR-- 436 G ++T+ A+D+DE + R+ Y I GN G F I SQ G + V + LD + + Sbjct: 307 IGGAIITVHASDSDEGPNGRVTYSIISGNDLGFFGIDSQT--GTLRVRKSLDLETQVHVY 364 Query: 437 ---YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 Y+LT+SA D G + TA++ I I N + P AP E +P+G V+ Sbjct: 365 DLIYILTISAQDQGTPRALNSTAIITIEIRSVNQFTPGLP-APSDVIHPESSPVGFEVVD 423 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 +ATD D G + I +++ NE F I+ TG IT K L+ Y L Sbjct: 424 WNATDKDFGADGIIRFAIFH--GNEG-----NTFDIDSSTGKITVGKKLNFTLYPRYFLH 476 Query: 551 VTARDGGVPS--LSDTTDVEISVVDVNDN 577 + D G S S T V + V ++NDN Sbjct: 477 INISDSGPTSQRRSLVTKVTVRVTNLNDN 505 Score = 178 bits (434), Expect = 5e-44 Identities = 141/498 (28%), Positives = 229/498 (45%), Gaps = 48/498 (9%) Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 Y I GN G F + + G + + LD+ + Y L + ATD G + +T Sbjct: 5 YAIYSGNQAGMFRV---DANGTVYLLGTLDYARAPSYRLVIRATDGGAKEMRKHADFTLT 61 Query: 461 ----DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 D N+ AP F + V+E + IG + V++ATD+D N Q++Y ++S Sbjct: 62 VLVEDINDNAPKFASDKTMVDVYETSKIGQVITVITATDADASTNGQVSYKIAS------ 115 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETM--SGY--LLTVTARDGGVPSLSDTTDVEISVV 572 + D F ++ +TG +T +K LD E + G+ L V A D G P L + Sbjct: 116 -GNDDDYFRLDSKTGHVTLSKSLDLEILHNEGWNRTLVVIATDHGTPRLHSNASFVFRLN 174 Query: 573 DVNDNEPVFKQQL-YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 VN+ PV+ + ++ ED LVG+ + ++ ATD D GL+G I Y + + E F Sbjct: 175 SVNEFPPVWTGNANLSLSLSEDILVGSKIGRLSATDRDYGLDGEIRYIILSGNGER-KFH 233 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST---VIVHIKIEDINDSPPVFE 688 +D +GVI + LDRE + L+ A D S +V IK++D+ND+ P F+ Sbjct: 234 LDEVTGVITIHAPLDRERTSYFRLRVQASDCSKKASSRRRVYAVVDIKVKDVNDNKPTFQ 293 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 + E + IG I + A D DEGPN V YSI G+D F ++++ G+ L Sbjct: 294 RKSYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSIISGNDLGFFGIDSQTGT----L 349 Query: 749 VTMVDLDYESPRKKYELV----IRA---ASPPLWNDVR-VEILVTDVNDNAPVMKDFQII 800 LD E+ Y+L+ I A +P N + I + VN P + + Sbjct: 350 RVRKSLDLETQVHVYDLIYILTISAQDQGTPRALNSTAIITIEIRSVNQFTPGLPAPSDV 409 Query: 801 FNNYKDCFPVGPFGRVPAYDADVTDK-------LQYRILSGNNANLILLNETTGSMTLSP 853 + + PVG D + TDK +++ I GN N ++ +TG +T+ Sbjct: 410 I--HPESSPVG----FEVVDWNATDKDFGADGIIRFAIFHGNEGNTFDIDSSTGKITVGK 463 Query: 854 QLNTNVPKLATMEVSVTD 871 +LN + + ++++D Sbjct: 464 KLNFTLYPRYFLHINISD 481 Score = 165 bits (400), Expect = 6e-40 Identities = 143/472 (30%), Positives = 215/472 (45%), Gaps = 51/472 (10%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND++P F + V E + G + + ATD D N +V Y I D Sbjct: 64 VEDINDNAPKFASDKTMVDVYETSKIGQVITVITATDADASTNGQVSYKIASGNDD---- 119 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY----TVLVKATDQASPVSD 128 D FR+D ++G + SLD E + T++V ATD +P Sbjct: 120 ---------------DYFRLDSKTGHVTLSKSLDLEILHNEGWNRTLVVIATDHGTP--- 161 Query: 129 RLSSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 RL S A+ + N+ P ++ ++S+ EDI V I ++ ATD D G + I Sbjct: 162 RLHSNASFVFRLNSVNEFPPVWTGNANLSLSLSEDILVGSK--IGRLSATDRDYGLDGEI 219 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLL- 244 RY I+ GN + +F +D ++G +++ LD E+ +RL ++A D + SR ++ Sbjct: 220 RYIILSGNGERKFHLDEVTGVITIHAPLDRERTSYFRLRVQASDCSKKASSRRRVYAVVD 279 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I ++DVNDN P F + V E IG +I+ V A D+DEG N +TY++ +GN Sbjct: 280 IKVKDVNDNKPTFQRKSYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSI----ISGN 335 Query: 305 VDLP-ITIDPRSGWVYTSGQLDRETQAK-----YQLLVTATDGGDPPRSATATXXXXXXX 358 DL ID ++G + LD ETQ Y L ++A D G P + Sbjct: 336 -DLGFFGIDSQTGTLRVRKSLDLETQVHVYDLIYILTISAQDQGTPRALNSTAIITIEIR 394 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416 +P +V E P G VV ATD D D + + I GN F I S Sbjct: 395 SVNQFTPGLPAPSDVIHPESSPVGFEVVDWNATDKDFGADGIIRFAIFHGNEGNTFDIDS 454 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANN 464 G+ ITV + L+F RY L ++ +DSG RS V + +T+ N+ Sbjct: 455 STGK--ITVGKKLNFTLYPRYFLHINISDSGPTSQRRSLVTKVTVRVTNLND 504 Score = 94.7 bits (225), Expect = 1e-18 Identities = 78/253 (30%), Positives = 115/253 (45%), Gaps = 31/253 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F+ + Y V E A G ++T+ A+D D G N V Y+I ++ + L Sbjct: 280 IKVKDVNDNKPTFQRKSYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSI--ISGNDL 337 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-----YTVLVKATDQASP 125 F ID ++G L R SLD E Y + + A DQ +P Sbjct: 338 G-----------------FFGIDSQTGTLRVRKSLDLETQVHVYDLIYILTISAQDQGTP 380 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + L+STA I + I N P + + + S + ATD D GA+ Sbjct: 381 RA--LNSTAIITIEIRSVNQFTPGLPAPSDVIHPE---SSPVGFEVVDWNATDKDFGADG 435 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQL 243 IR+AI GN F IDS +G +++ K L++ Y L I D G S RS T++ Sbjct: 436 IIRFAIFHGNEGNTFDIDSSTGKITVGKKLNFTLYPRYFLHINISDSGPTSQRRSLVTKV 495 Query: 244 LINIRDVNDNAPR 256 + + ++NDN R Sbjct: 496 TVRVTNLNDNGGR 508 >SB_40275| Best HMM Match : Cadherin (HMM E-Value=0) Length = 1747 Score = 196 bits (478), Expect = 2e-49 Identities = 225/768 (29%), Positives = 332/768 (43%), Gaps = 109/768 (14%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD+E SY L + A DG S+T + + I+DVND P F + L++ + EN G Sbjct: 222 LDFETKSSYTLEVTATDG---KFSDTAVVTVTIQDVNDLPPVFSSPLYESRIQENTGPGA 278 Query: 275 SIVRVQAYDADEGVNAELTYTMTD--KDYTGNVDLPITIDPRSGWV----YTSGQLDRET 328 +V V A D D + +++++ D KDY + + P + WV S QLDRE Sbjct: 279 GVVMVTASDID---SPTISFSLDDRGKDYFQITPIRAS-GPGNVWVGDIRTGSKQLDREE 334 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 V A DG +A A F Y + E++P GT V+ + Sbjct: 335 SPVKVFTVIANDG---KHTAQAEIRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYI 391 Query: 389 TATDADE-----DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYVLTVS 442 A D D+ + +L YE+T + +FSI + GLI D +Q ++ + V Sbjct: 392 QAVDDDDPLAGGNAKLSYELT-DSAGDKFSIDPLS--GLIKTKVTFDREQTPNKFKVRVK 448 Query: 443 ATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 ATD+G +A V I+++DAN++ P F Y SV E+AP G +VL V+ATD DVG Sbjct: 449 ATDAGNPRLSASVDGIIHVSDANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDVGP 508 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NA+ + + N+ A F I+P G + + +LD E Y +T+T D G+P Sbjct: 509 NAEFEFVVVQ--GNDPHA-----FYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPP 561 Query: 561 L--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 L +T V I ++D NDN P F ++Y A+++ED V V A D D G NG + Sbjct: 562 LQGDETAYVVIEILDANDNAPEFIPKIYNASVLEDVGARQPVLTVTAVDRDSGPNGNFTF 621 Query: 619 ELDPKDREEGSFVIDP-----ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 +DP+ + +F I+P + G+IRT LD+E L + + + Sbjct: 622 AIDPRSDPDDAFTIEPNPNKCSIGIIRTRVPLDQEKTHRSTL-GYSYGRRKGVSARQFVT 680 Query: 674 HIKIEDINDSPPVFESD-CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 +K D P F D +TF I T+GE DP N V D Sbjct: 681 KLKAYD----PDAFVKDQVITFSIYNG-----TVGENFKLDPVSVTNESV--------DL 723 Query: 733 NSFSLETRQGSDKAEL-VTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNA 791 +S+ + R+ + ++ + VD P+K + V V++L DVNDNA Sbjct: 724 HSYGVFDREAAPVWKIGIEAVDNVGPKPQKNFTYVY------------VDVL--DVNDNA 769 Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851 P II N Y F G G+ P Y D D +E T L Sbjct: 770 PKDGSLLIIVNAYDGNFTGGVIGK-PYYQDDDFDG----------------DENT--YEL 810 Query: 852 SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDM-TAEQFLS 910 + Q + P T V V VR I +E + N + V DM F+ Sbjct: 811 NSQSRKDSPSTVTSSVRVL-------------VRRIDKEAVDNGVAVEFTDMRKVGYFVG 857 Query: 911 PLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDA 958 F D LA+ + P +I IFSVQ D G + V F+ D+ Sbjct: 858 DYYKGFEDVLASTLGVPTGDIKIFSVQKAHD-NGLAVVVFFTVAAKDS 904 Score = 186 bits (454), Expect = 2e-46 Identities = 164/552 (29%), Positives = 251/552 (45%), Gaps = 41/552 (7%) Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 DG P R T ++ N D + T+ + ++ V Y V V A D +A Sbjct: 129 DGSEPHRRVTYEMKDNPNFQIDASTGMITT--KTTLDREVTPKYD-VEVTAKDGVNKESA 185 Query: 291 ELTYTMTDKDYTGNVDLPITID---PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347 L T+ D++ V P + P + +G+LD ET++ Y L VTATDG S Sbjct: 186 ILYITVVDQNDQPPVFAPKSYAISVPEDSPIVVNGKLDFETKSSYTLEVTATDG---KFS 242 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN 407 TA F YE + E+ PG VV +TA+D D + + + + Sbjct: 243 DTAVVTVTIQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDIDSPT-ISFSL---D 298 Query: 408 TRGR--FSITSQNGRG--------LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457 RG+ F IT G + T ++ LD ++ V TV A D G + A +++ Sbjct: 299 DRGKDYFQITPIRASGPGNVWVGDIRTGSKQLDREESPVKVFTVIAND-GKHTAQAEIRV 357 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISN 514 N+TD N+ AP F +PY V E+ P GT+V+ + A D D G NA+++Y L+ + Sbjct: 358 NLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYELTDSAGD 417 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRE-TMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + F I+P +G I T DRE T + + + V A D G P LS + D I V D Sbjct: 418 K--------FSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVSD 469 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 ND++P F ++ Y ++ E+A G SV +V ATD DVG N + + + + +F ID Sbjct: 470 ANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDVGPNAEFEFVV-VQGNDPHAFYID 528 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDC 691 P +G + + LD E + + D G PP T V I+I D ND+ P F Sbjct: 529 PFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEFIPKI 588 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELV- 749 + E+ + + A D D GPN ++I D ++F++E ++ Sbjct: 589 YNASVLEDVGARQPVLTVTAVDRDSGPNGNFTFAIDPRSDPDDAFTIEPNPNKCSIGIIR 648 Query: 750 TMVDLDYESPRK 761 T V LD E + Sbjct: 649 TRVPLDQEKTHR 660 Score = 162 bits (393), Expect = 4e-39 Identities = 176/651 (27%), Positives = 270/651 (41%), Gaps = 72/651 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND PVF YE+ ++E G V+ + A+D D TI D Sbjct: 249 VTIQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDID-------SPTISFSLDD-- 299 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D +V+ D R+G+ LDRE+ V A D + Sbjct: 300 RGKDYFQITPIRASGPGNVWVGDIRTGS----KQLDREESPVKVFTVIAND------GKH 349 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-SVTDNPVIAKIKATDADVGANSAIRY 189 ++ A I VN+ D NDN P+F Y V+E+ S T I + D G N+ + Y Sbjct: 350 TAQAEIRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSY 409 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + +FSID LSG + T D EQ +++ ++A D G+P S + +I++ Sbjct: 410 ELTDSAGD-KFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVS 468 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D ND+ P+F ++ SV+EN P GYS++RV A D D G NAE + + GN Sbjct: 469 DANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDVGPNAEFEFVVVQ----GNDPHA 524 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXF 366 IDP +G V SG LD E + +Y + +T D G PP TA F Sbjct: 525 FYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEF 584 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGR--- 420 +P Y + ED PV+T+TA D D ++ + F+I + Sbjct: 585 IPKIYNASVLEDVGARQPVLTVTAVDRDSGPNGNFTFAIDPRSDPDDAFTIEPNPNKCSI 644 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G+I PLD QE+ + T+ S GR + +T Y P Sbjct: 645 GIIRTRVPLD--QEKTHRSTLGY--SYGRRKGVSARQFVTKLKAYDP------------- 687 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA + V+ S + VG N ++ ++NE+V H + + D Sbjct: 688 DAFVKDQVITFSIYNGTVGENFKLD---PVSVTNESVDLH--------------SYGVFD 730 Query: 541 RETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 RE + + + A D G + T V + V+DVNDN P L N + G Sbjct: 731 REAAPVWKIGIEAVDNVGPKPQKNFTYVYVDVLDVNDNAPKDGSLLIIVNAYDGNFTGGV 790 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 + + D D YEL+ + R++ + S V + +D+E+V Sbjct: 791 IGKPYYQDDDFD-GDENTYELNSQSRKDSPSTV--TSSVRVLVRRIDKEAV 838 Score = 147 bits (356), Expect = 1e-34 Identities = 99/310 (31%), Positives = 151/310 (48%), Gaps = 34/310 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVT 66 ++N+ D ND++P F Y V E SGT+V+ ++A D D G NA++ Y + Sbjct: 356 RVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYEL---- 411 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASP 125 D F ID SG + T+ + DRE+ ++ V VKATD +P Sbjct: 412 ----------------TDSAGDKFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNP 455 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 RLS++ +++ D ND+ P+F+EK Y SV E + + ++ ATD DVG N+ Sbjct: 456 ---RLSASVDGIIHVSDANDHKPKFTEKFYRGSVAE--NAPPGYSVLRVTATDEDVGPNA 510 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQL 243 + ++ GN F ID +G V + LDYE+ + Y + + D G P T + Sbjct: 511 EFEFVVVQGNDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYV 570 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +I I D NDNAP F ++ SV E+V ++ V A D D G N T+ + D Sbjct: 571 VIEILDANDNAPEFIPKIYNASVLEDVGARQPVLTVTAVDRDSGPNGNFTFAI---DPRS 627 Query: 304 NVDLPITIDP 313 + D TI+P Sbjct: 628 DPDDAFTIEP 637 Score = 88.2 bits (209), Expect = 8e-17 Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 20/232 (8%) Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 YTAS+ E+ G+TV ++AT S A+I+Y + F + P G I Sbjct: 2 YTASINENMETGSTVTRITATSST---GAEISYENVDTNPRAKIL-----FRVQPD-GYI 52 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN--IM 591 T D E + Y + A+D L T V I+++DVND P F + T N ++ Sbjct: 53 ITGDRPDYERGTTYNMQFAAKDKKT-LLYSTVKVVINIIDVNDVSPAFLLAINTRNARVL 111 Query: 592 EDALVGTSVSQVGATDADVG-LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 E+ T V + A D D + R+ YE+ ++ +F ID ++G+I T LDRE Sbjct: 112 ENKPAPTKVISMKAIDDDGSEPHRRVTYEM----KDNPNFQIDASTGMITTKTTLDREVT 167 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 +D++ A DG + I++I + D ND PPVF + E+SPI Sbjct: 168 PKYDVEVTAKDG---VNKESAILYITVVDQNDQPPVFAPKSYAISVPEDSPI 216 Score = 87.0 bits (206), Expect = 2e-16 Identities = 81/271 (29%), Positives = 112/271 (41%), Gaps = 30/271 (11%) Query: 1089 CQG--CSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLY-- 1144 C G C Y +CE+ R+F +S++ P L L+ +F T+T GLL+Y Sbjct: 1018 CPGFVCKCPTGYHGPLCEMTTRTFYGNSYIWLPKLMTYSLSDLEFEFMTKTADGLLVYQG 1077 Query: 1145 ---NGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI 1201 G N DF+A+ L RGG L S L ++ + DG WHTV++ Sbjct: 1078 PEREGANNGLKDFIAVVL------RGGRVELFVSLGLDPVTVKMDKGPRLDDGEWHTVQV 1131 Query: 1202 EYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHR--FLDLT 1259 + I +I+D C L L D RK C + R FLD Sbjct: 1132 LRNMKDIEIIIDRCSTAL-LEHKPD-----GTVVENRK----SCHVYGRMLGRSVFLDGF 1181 Query: 1260 GPLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCS 1318 GPLQIGG+ N F + F GC+ + +H DL + + GC + S C Sbjct: 1182 GPLQIGGVSNPNMDFPDIPYTGFKGCVRNIKDNHNLYDLKNPLKVVNAPEGC-QLASACP 1240 Query: 1319 SAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348 C N C L IC C G++GK C Sbjct: 1241 E--CKNDGYCEPLMARDSICVCNPGYSGKHC 1269 Score = 82.2 bits (194), Expect = 5e-15 Identities = 70/228 (30%), Positives = 105/228 (46%), Gaps = 19/228 (8%) Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y + E+ G+ V +TAT + + YE N R + Q +IT +P D Sbjct: 2 YTASINENMETGSTVTRITATSST-GAEISYENVDTNPRAKILFRVQPDGYIITGDRP-D 59 Query: 431 FKQERRYVLTVSATDSGGRS-DTAMVQINITDANNYAPVFENAPYT--ASVFEDAPIGTT 487 +++ Y + +A D T V INI D N+ +P F A T A V E+ P T Sbjct: 60 YERGTTYNMQFAAKDKKTLLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPTK 119 Query: 488 VLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V+ + A D D + ++TY + + F I+ TG ITT LDRE Sbjct: 120 VISMKAIDDDGSEPHRRVTYEMKD----------NPNFQIDASTGMITTKTTLDREVTPK 169 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 Y + VTA+DG ++ + I+VVD ND PVF + Y ++ ED+ Sbjct: 170 YDVEVTAKDG---VNKESAILYITVVDQNDQPPVFAPKSYAISVPEDS 214 Score = 64.5 bits (150), Expect = 1e-09 Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 29/160 (18%) Query: 11 INVLDCNDHSPVF--EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 IN++D ND SP F + A V E + T V+++KA D D G T E+ Sbjct: 87 INIIDVNDVSPAFLLAINTRNARVLENKPAPTKVISMKAIDDD-GSEPHRRVTYEMKD-- 143 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 NP F+ID +G + T+ +LDRE +Y V V A D + Sbjct: 144 --NPN----------------FQIDASTGMITTKTTLDREVTPKYDVEVTAKDGVN---- 181 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN 168 +A +++ ++D ND P F+ K+Y +SV ED + N Sbjct: 182 --KESAILYITVVDQNDQPPVFAPKSYAISVPEDSPIVVN 219 Score = 56.8 bits (131), Expect = 2e-07 Identities = 64/260 (24%), Positives = 104/260 (40%), Gaps = 14/260 (5%) Query: 52 IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111 I +N E T+ +TA + + + +FR+ G ++T D E+ Sbjct: 6 INENMETGSTVTRITATSSTGAEISYENVDTNPRAKILFRVQP-DGYIITGDRPDYERGT 64 Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171 Y + A D+ + L ST + +NIID ND P F T + + + Sbjct: 65 TYNMQFAAKDKKT----LLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPTKV 120 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 +KA D D + R F ID+ +G ++ TLD E Y + + A+D Sbjct: 121 ISMKAIDDD--GSEPHRRVTYEMKDNPNFQIDASTGMITTKTTLDREVTPKYDVEVTAKD 178 Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 G + L I + D ND P F + SV E+ PI +V + D + + Sbjct: 179 G---VNKESAILYITVVDQNDQPPVFAPKSYAISVPEDSPI---VVNGK-LDFETKSSYT 231 Query: 292 LTYTMTDKDYTGNVDLPITI 311 L T TD ++ + +TI Sbjct: 232 LEVTATDGKFSDTAVVTVTI 251 Score = 56.4 bits (130), Expect = 3e-07 Identities = 49/163 (30%), Positives = 72/163 (44%), Gaps = 10/163 (6%) Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 P I N LD E+ +++ L+ A DG S T +V + I+D+ND PPVF S Sbjct: 211 PEDSPIVVNGKLDFETKSSYTLEVTATDGKF---SDTAVVTVTIQDVNDLPPVFSSPLYE 267 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK--AELVT- 750 I EN+ G + + A D D P +G D + + ++ T Sbjct: 268 SRIQENTGPGAGVVMVTASDIDS-PTISFSLDDRGKDYFQITPIRASGPGNVWVGDIRTG 326 Query: 751 MVDLDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 LD E SP K + ++ ++RV + TDVNDNAP Sbjct: 327 SKQLDREESPVKVFTVIANDGKHTAQAEIRVNL--TDVNDNAP 367 Score = 37.9 bits (84), Expect = 0.12 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 1477 SDVGFFEGCIQDVRIGTAQSLLNRPTV---RENVRDGCQSRADCMLSICPPYSKCVTSWD 1533 S +G F GCI + A ++ + P++ R+NV DGC C+ + C CV + Sbjct: 1482 SVLGDFGGCIAGTSVNGA-NMESDPSIKVHRQNVLDGCP----CLSNFCANGGTCVDAMP 1536 Query: 1534 SSTCTCEAGRVGPQCVSACELGPCG 1558 C C G GP C P G Sbjct: 1537 PY-CICAPGWTGPLCTIVVTAPPVG 1560 Score = 34.3 bits (75), Expect = 1.4 Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 22/151 (14%) Query: 1418 LSDGAWHRIEIKWLGTDISVTVDYGLRTVLM-----PMLANK----IQGQYIGK------ 1462 L DG WH +++ DI + +D +L ++ N+ + G+ +G+ Sbjct: 1121 LDDGEWHTVQVLRNMKDIEIIIDRCSTALLEHKPDGTVVENRKSCHVYGRMLGRSVFLDG 1180 Query: 1463 ---ILIGGLDTTAGLLASDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADC 1517 + IGG+ + + D+ + F+GC+++++ L P N +GCQ + C Sbjct: 1181 FGPLQIGGV-SNPNMDFPDIPYTGFKGCVRNIKDNHNLYDLKNPLKVVNAPEGCQLASAC 1239 Query: 1518 MLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548 Y + + + D S C C G G C Sbjct: 1240 PECKNDGYCEPLMARD-SICVCNPGYSGKHC 1269 >SB_35963| Best HMM Match : Cadherin (HMM E-Value=0) Length = 864 Score = 191 bits (466), Expect = 6e-48 Identities = 168/607 (27%), Positives = 277/607 (45%), Gaps = 51/607 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI++ D N++ PVFE +Y ++ E T++L ++A D DIG+N + Y + Sbjct: 235 QIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARDADIGRNGGIYYYLR------ 288 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N +D ++ + +D +SG T R++ Q + SD Sbjct: 289 -NTQD--FTIDAITGVIRPIRMLDFQSGQQRTLEVTARDR-GSSPKAANVNVQVTIRSDI 344 Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAI 187 + + D + P F E ++T+S+ ED V N I +KA D D G+ N + Sbjct: 345 SGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPV--NGAIQVVKANDPDAGSTNGQL 402 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQD--GGSPSRSNTTQ 242 RY++ G N F+IDS SG V+L L+Y+ + LV+ A D G S + S + Sbjct: 403 RYSLSGNN---NFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVN 459 Query: 243 LLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 L I + DV N+NAP F + +VSE+ +G +I RV A D+D+G + ++ Y++ Sbjct: 460 LKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDDGSDGQVVYSIIQGS 519 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G + T +G + + LDRE + Y L++ A D P+S+ Sbjct: 520 GLGVFQVQAT----TGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVD 575 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F Y + E P T V + D D + Y ITG ++ F I + Sbjct: 576 DHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGASS---FKIVPTS-- 630 Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTA 476 GLI P+D E Y L V+AT + + T V + IT PVF+N PY Sbjct: 631 GLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESPPVFKNTPYAI 690 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E+ ++ V+A D+ + YS+ S + F I+ ++G ++ Sbjct: 691 SVPENQGSIANLVCVAAIDTK---GQPVIYSIES---------RGEPFGIDSKSGRFSSL 738 Query: 537 KLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + D ET Y + ++A+ G P+ ++ ++DV I++ D D P F Q Y ++ E A Sbjct: 739 QSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEGAS 797 Query: 596 VGTSVSQ 602 V +++S+ Sbjct: 798 VRSTLSR 804 Score = 179 bits (435), Expect = 3e-44 Identities = 190/677 (28%), Positives = 298/677 (44%), Gaps = 80/677 (11%) Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIG 193 T+ + + D N+ P F Y + E+ + T + K A D D + RY I+ Sbjct: 121 TLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKD--RSGIDRYEIVS 178 Query: 194 GNTQMQFSIDSLSGDVS---LVKTLDYEQVR-----SYRLVIRAQDGGSPSRSNTTQLLI 245 GN + F ++ + ++K + VR S L +RA DGG TT++ I Sbjct: 179 GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVRANDGGG--LHGTTRIQI 236 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 +I+D N+N P F S + ++ E+ P+ SI+RV+A DAD G N + Y Y N Sbjct: 237 DIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARDADIGRNGGIYY------YLRNT 290 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX- 364 TID +G + LD ++ + L VTA D G P++A Sbjct: 291 Q-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIRSDISGYPP 349 Query: 365 --------------XFMPGQ-YEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGG 406 F G + + + ED P + + A D D + +L Y ++G Sbjct: 350 VVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQLRYSLSGN 409 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDTAMVQINI---- 459 N F+I S +G ++T+ L++K + L V+ATD G+S +N+ Sbjct: 410 NN---FAIDSTSG--VVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVNLKIEV 464 Query: 460 --TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 D NN APVF +V ED +G T+ VSATDSD G + Q+ YS+ I + Sbjct: 465 LDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDDGSDGQVVYSI---IQGSGL 521 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F + TG + LDRE MS Y L + A D S V + + DV+D+ Sbjct: 522 G----VFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDH 577 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F Q +Y A E + T V+ V D D+G + + Y + SF I P SG Sbjct: 578 FPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSI----TGASSFKIVPTSG 631 Query: 638 VIRTNKALD-RESVATHDL--KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +I T +D +T++L A + + GT + +T V+++I +SPPVF++ Sbjct: 632 LILTTGPIDLTTEPSTYELVVTATSTNYGT-TKRATGQVNVEITSKTESPPVFKNTPYAI 690 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 + EN + + A D P V YSI+ + F ++++ G ++ Sbjct: 691 SVPENQGSIANLVCVAAIDTKGQP---VIYSIESRGE--PFGIDSKSG----RFSSLQSF 741 Query: 755 DYESPRKKYELVIRAAS 771 DYE+ KY + I A S Sbjct: 742 DYET-ADKYRIQISAQS 757 Score = 175 bits (425), Expect = 6e-43 Identities = 201/739 (27%), Positives = 319/739 (43%), Gaps = 82/739 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-KATDQDIGKNAEVEYTIELVTAD 68 +I V D N+ P F Y + E A+ GTTV L K +D ++ Y E+V+ + Sbjct: 123 RITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKDRSGIDRY--EIVSGN 180 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 E Q + + TR D + + T+ V+A D Sbjct: 181 ----ERGYFVAETKTVGAQKFLVLKATN----TRIVRDPARPS-ITLTVRANDGGG---- 227 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L T I ++I D N+N P F + YTV++ ED V + I +++A DAD+G N I Sbjct: 228 -LHGTTRIQIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTS--ILRVRARDADIGRNGGIY 284 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + NTQ F+ID+++G + ++ LD++ + L + A+D GS ++ + + IR Sbjct: 285 YYL--RNTQ-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIR 341 Query: 249 -DVND-------------NAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEG-VNAE 291 D++ N P + S F S+ E+ P+ +I V+A D D G N + Sbjct: 342 SDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQ 401 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD---RETQAKYQLLVTATD----GGDP 344 L Y++ +GN + ID SG V QL+ Q L+VTATD G Sbjct: 402 LRYSL-----SGNNN--FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGAL 454 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402 S F P Q E+ ++ED G + ++ATD+D+ D ++ Y Sbjct: 455 SASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDDGSDGQVVYS 514 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINIT 460 I G+ G F + + G + VA PLD ++ Y L + A D +S V + I Sbjct: 515 IIQGSGLGVFQVQATTGD--LIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQ 572 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 D +++ P F Y A E +P T V VV D D+G ++YS++ S Sbjct: 573 DVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGASS------- 623 Query: 521 DQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNE 578 F I P +G I T +D T S Y L VTA + T V + + ++ Sbjct: 624 ---FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESP 680 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 PVFK Y ++ E+ ++ V A D + Y ++ + F ID SG Sbjct: 681 PVFKNTPYAISVPENQGSIANLVCVAAIDTK---GQPVIYSIESRGE---PFGIDSKSGR 734 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 + ++ D E+ + ++ A G P +S+ V I I+D D PP F + Sbjct: 735 FSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVP 793 Query: 698 ENSPIGTTIGE-IRAHDPD 715 E + + +T+ IR D D Sbjct: 794 EGASVRSTLSRGIRFVDED 812 Score = 158 bits (383), Expect = 7e-38 Identities = 161/612 (26%), Positives = 264/612 (43%), Gaps = 66/612 (10%) Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR----FYTSLFQESVSENVPIGYSIVR 278 Y L + + G L I + D N+ P FY E ++ +G + + Sbjct: 102 YVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVG-GLEK 160 Query: 279 VQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQLLV 336 A D D G++ + ++ Y + T+ ++ R+ + L V Sbjct: 161 CHAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTV 220 Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-- 394 A DGG T F +Y V + ED P T ++ + A DAD Sbjct: 221 RANDGGG--LHGTTRIQIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARDADIG 278 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 + ++Y + NT+ F+I + G+I + LDF+ ++ L V+A D G A Sbjct: 279 RNGGIYYYLR--NTQD-FTIDAIT--GVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAAN 333 Query: 455 VQINIT---DANNYAPVF---------------ENAPYTASVFEDAPIGTTVLVVSATDS 496 V + +T D + Y PV E + +T S+ ED P+ + VV A D Sbjct: 334 VNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDP 393 Query: 497 DVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLT 550 D G N Q+ YSLS + F I+ +G +T L+ + + ++T Sbjct: 394 DAGSTNGQLRYSLSG----------NNNFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVT 443 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTSVSQVGATDA 608 T R+G +LS + +++I V+DV+DN PVF Q + ED VG ++ +V ATD+ Sbjct: 444 ATDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDS 503 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G +G++ Y + + G F + +G + LDRE ++ +DL A D T P+S Sbjct: 504 DDGSDGQVVYSI-IQGSGLGVFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKS 562 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S + V +KI+D++D P F E SP T + ++ D D G + V YSI G Sbjct: 563 SNLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITG 620 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR----VEILV 784 ++SF + G ++T +D + YELV+ A S R V + + Sbjct: 621 ---ASSFKIVPTSGL----ILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEI 673 Query: 785 TDVNDNAPVMKD 796 T ++ PV K+ Sbjct: 674 TSKTESPPVFKN 685 Score = 155 bits (375), Expect = 6e-37 Identities = 149/515 (28%), Positives = 235/515 (45%), Gaps = 50/515 (9%) Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK--Q 433 E+EP G V + + ++E + T + R S++G ++ PL + + Sbjct: 41 ENEPEGFRVFSFPSPPSNEIYSFFRALDTASQSALRLFDISEDG--VVVTKNPLVYTDGE 98 Query: 434 ERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 E YVLTV G ++I +TD NN+ P F Y + E+A GTTV + Sbjct: 99 ENLYVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGL 158 Query: 492 SATDSDVGINAQIT-YSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGY 547 ++ + I Y + S NE + + Q + T +++ Sbjct: 159 EKCHAEDKDRSGIDRYEIVS--GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSI 216 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LTV A DGG L TT ++I + D N+N PVF++ YT I ED V TS+ +V A D Sbjct: 217 TLTVRANDGG--GLHGTTRIQIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARD 274 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 AD+G NG I+Y L R F ID +GVIR + LD +S L+ A D G+ P+ Sbjct: 275 ADIGRNGGIYYYL----RNTQDFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPK 330 Query: 668 SSTVIVHIKIE-DIN--------------DSPPVF-ESDCLTFYISENSPIGTTIGEIRA 711 ++ V V + I DI+ + PPVF E T I E+ P+ I ++A Sbjct: 331 AANVNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKA 390 Query: 712 HDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 +DPD G N + YS+ G +N+F++++ G L T ++ + +LV+ A Sbjct: 391 NDPDAGSTNGQLRYSLSG---NNNFAIDSTSG--VVTLQTQLEYKGNPAQDVIDLVVTAT 445 Query: 771 -----SPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822 S L V ++E+L D N+NAPV Q+ +D RV A D+D Sbjct: 446 DRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDD 505 Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 ++ Y I+ G+ + + TTG + ++ L+ Sbjct: 506 GSDGQVVYSIIQGSGLGVFQVQATTGDLIVAAPLD 540 Score = 76.6 bits (180), Expect = 3e-13 Identities = 74/294 (25%), Positives = 132/294 (44%), Gaps = 36/294 (12%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ + + D +DH P F Y A E + T V +K D D+G++ V Y+I + Sbjct: 565 LYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITGAS 622 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASP 125 + F+I SG +LT +D + + Y ++V AT Sbjct: 623 S----------------------FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYG 660 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + R +T ++V I ++ P F Y +SV E+ N V + A D Sbjct: 661 TTKR--ATGQVNVEITSKTESPPVFKNTPYAISVPENQGSIANLVC--VAAIDT---KGQ 713 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLL 244 + Y+I + F IDS SG S +++ DYE YR+ I AQ G +P+ ++++ + Sbjct: 714 PVIYSI--ESRGEPFGIDSKSGRFSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVA 771 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 I I+D D P+F S ++ SV E + ++ R + ++ ++ +L +M + Sbjct: 772 ITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDEDTLSTQLECSMEE 824 >SB_7364| Best HMM Match : Cadherin (HMM E-Value=0) Length = 408 Score = 182 bits (443), Expect = 4e-45 Identities = 133/421 (31%), Positives = 200/421 (47%), Gaps = 36/421 (8%) Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 GNT F+I++ SG + + LD E Y L + A D G P+ +++T + I++ DVNDN Sbjct: 2 GNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDN 61 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P + EN P G + + A D DEG NA + ++ Y D +I P Sbjct: 62 KPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFS----GY-AVPDGKFSIKP 116 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFMPGQYE 372 +G + LDRE Q ++ ATD G PP S+ + F P Y Sbjct: 117 -NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYS 175 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 V ++E+ P +V + A++ DE +L ++I+ G+ G F+I N G+I+ +PLD + Sbjct: 176 VNISENGPSEEVIVQVNASERDE-GKLLFKISSGDPGGYFTI--HNVTGVISTRKPLDRE 232 Query: 433 QERRYVLTVSATDSGGRSDTAM--------------------VQINITDANNYAPVFENA 472 R+ LT++A D G S A+ V I + D N++APV E Sbjct: 233 MVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPVIEQC 292 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TG 531 SV E+A IG+ V ++A D D N +ITYS+ + N + F + G Sbjct: 293 EQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFN--ITTQRLPFSSGSRYRG 350 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I T LLDRE Y +TVTA DG + T ++ + + DVNDN PVF Q ++ Sbjct: 351 IIITAGLLDRERQDNYNITVTASDGNHIA---TCNITVRITDVNDNSPVFNQTTMNISLH 407 Query: 592 E 592 E Sbjct: 408 E 408 Score = 155 bits (376), Expect = 5e-37 Identities = 124/410 (30%), Positives = 188/410 (45%), Gaps = 37/410 (9%) Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463 GNT F+I +++G + T+ LD + RY+LTV A+D G + + V I++ D N Sbjct: 2 GNTDNSFAINNKSG-SIYTLLH-LDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVN 59 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 + P N P E+ P G+ V ++SA+D D G NA++ +S A D + Sbjct: 60 DNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFS--------GYAVPDGK 111 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFK 582 F I P G I LDRE + ++ A D G P S +I + D NDN PVF Sbjct: 112 FSIKP-NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFD 170 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Y+ NI E+ + QV A++ D G++ +++ D G F I +GVI T Sbjct: 171 PVHYSVNISENGPSEEVIVQVNASERD---EGKLLFKISSGD-PGGYFTIHNVTGVISTR 226 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSS-----TVI-------------VHIKIEDINDSP 684 K LDRE V+ DL A D G P + + T++ V I + D ND Sbjct: 227 KPLDREMVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFA 286 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGS 743 PV E +SEN+ IG+ + I A D D+ N + YS+ + + L GS Sbjct: 287 PVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGS 346 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793 ++ L + Y + + A+ + + +TDVNDN+PV Sbjct: 347 RYRGIIITAGLLDRERQDNYNITVTASDGNHIATCNITVRITDVNDNSPV 396 Score = 147 bits (355), Expect = 2e-34 Identities = 125/423 (29%), Positives = 192/423 (45%), Gaps = 43/423 (10%) Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 GN D I+ +SG +YT LDRET +Y L V A+D G+P +++ Sbjct: 2 GNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDN 61 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSITSQNGRG 421 V E+ PPG+ V L+A+D DE + +G G+FSI NG Sbjct: 62 KPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGKFSI-KPNGE- 119 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASV 478 I V LD + + R+V ATDSG S I I D N+ PVF+ Y+ ++ Sbjct: 120 -IMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNI 178 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ P ++ V+A++ D G ++ + +SS F I+ TG I+T K Sbjct: 179 SENGPSEEVIVQVNASERDEG---KLLFKISS-------GDPGGYFTIHNVTGVISTRKP 228 Query: 539 LDRETMSGYLLTVTARDGGVPS------------------LSDTTDVEISVVDVNDNEPV 580 LDRE +S + LT+TA D G PS ++ V I V D ND PV Sbjct: 229 LDREMVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPV 288 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS---- 636 +Q ++ E+A +G++V+ + A D D N +I Y + + + +S Sbjct: 289 IEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRY 348 Query: 637 -GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 G+I T LDRE +++ A DG +T + ++I D+ND+ PVF + Sbjct: 349 RGIIITAGLLDRERQDNYNITVTASDGN---HIATCNITVRITDVNDNSPVFNQTTMNIS 405 Query: 696 ISE 698 + E Sbjct: 406 LHE 408 Score = 130 bits (314), Expect = 2e-29 Identities = 126/421 (29%), Positives = 193/421 (45%), Gaps = 50/421 (11%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ +SG++ T LDRE RY + V A+D+ P + S+ TIHVN D NDN P Sbjct: 8 FAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNS-STNVTIHVN--DVNDNKPN 64 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR---YAIIGGNTQMQFSIDSLS 206 + V E + ++ + A+D D G+N+ + YA+ G +FSI + Sbjct: 65 ITNNPGVVVTRE--NTPPGSLVYILSASDLDEGSNARVAFSGYAVPDG----KFSIKP-N 117 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQES 265 G++ + +LD E + A D G P S+ I I D NDN P F + + Sbjct: 118 GEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVN 177 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 +SEN P IV+V A + DEG +L + ++ D G TI +G + T LD Sbjct: 178 ISENGPSEEVIVQVNASERDEG---KLLFKISSGDPGGY----FTIHNVTGVISTRKPLD 230 Query: 326 RETQAKYQLLVTATDGGDPPR--------------SATATXXXXXXXXXXXXXXFMP--G 369 RE +++ L +TA D G P R S F P Sbjct: 231 REMVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPVIE 290 Query: 370 QYE--VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ-----NG--- 419 Q E V ++E+ G+ V ++ A D D+ + + GN+ F+IT+Q +G Sbjct: 291 QCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNS--AFNITTQRLPFSSGSRY 348 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 RG+I A LD +++ Y +TV+A+D G T + + ITD N+ +PVF S+ Sbjct: 349 RGIIITAGLLDRERQDNYNITVTASD-GNHIATCNITVRITDVNDNSPVFNQTTMNISLH 407 Query: 480 E 480 E Sbjct: 408 E 408 Score = 119 bits (287), Expect = 3e-26 Identities = 107/351 (30%), Positives = 159/351 (45%), Gaps = 48/351 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND+ P RE G+ V L A+D D G NA V ++ V Sbjct: 53 IHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAV----- 107 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P+ F I +G ++ R SLDRE R+ ATD P + Sbjct: 108 -PDGK--------------FSIK-PNGEIMVRDSLDREAQNRFVFYAMATDSGQPPFN-- 149 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS + + I D+NDN P F Y+V++ E + VI ++ A++ D G + + Sbjct: 150 SSMVSFDILIADENDNNPVFDPVHYSVNISE--NGPSEEVIVQVNASERDEG---KLLFK 204 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR------SNTTQLL 244 I G+ F+I +++G +S K LD E V + L I A+D G PSR +LL Sbjct: 205 ISSGDPGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVCTLLELL 264 Query: 245 IN------------IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 ++ + D ND AP SVSEN IG ++ + A D D+ N ++ Sbjct: 265 VSKRVAQRGRVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKI 324 Query: 293 TYTMTDKDYTGNVD-LPITIDPR-SGWVYTSGQLDRETQAKYQLLVTATDG 341 TY++ + + LP + R G + T+G LDRE Q Y + VTA+DG Sbjct: 325 TYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTASDG 375 Score = 82.2 bits (194), Expect = 5e-15 Identities = 68/248 (27%), Positives = 112/248 (45%), Gaps = 10/248 (4%) Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 + SF I+ SG I T LDRE+ + L +A D G P +S+ V I + D+ND+ P Sbjct: 5 DNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPN 64 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 ++ EN+P G+ + + A D DEG NA V +S D FS++ Sbjct: 65 ITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGK-FSIKPN-----G 118 Query: 747 ELVTMVDLDYESPRKK--YELVIRAASPPLWND-VRVEILVTDVNDNAPVMKDFQIIFNN 803 E++ LD E+ + Y + + PP + V +IL+ D NDN PV N Sbjct: 119 EIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNI 178 Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863 ++ +V A + D KL ++I SG+ ++ TG ++ L+ + Sbjct: 179 SENGPSEEVIVQVNASERD-EGKLLFKISSGDPGGYFTIHNVTGVISTRKPLDREMVSRF 237 Query: 864 TMEVSVTD 871 + ++ D Sbjct: 238 DLTITAED 245 Score = 74.1 bits (174), Expect = 1e-12 Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 52/281 (18%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND++PVF+ Y ++ E S ++ + A+++D GK ++ + D Sbjct: 157 ILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDEGK-----LLFKISSGDP- 210 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP----- 125 F I +G + TR LDRE V+R+ + + A D+ P Sbjct: 211 ----------------GGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGRPSRMAL 254 Query: 126 ----------VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK 175 VS R++ + + + D+ND P + VSV E+ + +A I Sbjct: 255 GYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPVIEQCEQLVSVSENAHI--GSAVASIN 312 Query: 176 ATDADVGANSAIRYAIIGGNT-------QMQFSIDS-LSGDVSLVKTLDYEQVRSYRLVI 227 A D D +N+ I Y++ GN+ ++ FS S G + LD E+ +Y + + Sbjct: 313 AVDKDDPSNTKITYSV--GNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITV 370 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 A DG + N T + I DVNDN+P F + S+ E Sbjct: 371 TASDGNHIATCNIT---VRITDVNDNSPVFNQTTMNISLHE 408 >SB_18765| Best HMM Match : Cadherin (HMM E-Value=0) Length = 389 Score = 175 bits (425), Expect = 6e-43 Identities = 121/370 (32%), Positives = 177/370 (47%), Gaps = 26/370 (7%) Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 D SG + +G L + Y ++V TDGG P + A Y Sbjct: 16 DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------Y 69 Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQP 428 +V + E E V+ L ++ H+ ++GGN S+ S NG L + P Sbjct: 70 DVSVLEGEA-NVQVMDLKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTP 122 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD + +++L +S T+ G V +N+ D N+ P+F++ + SV E +GT Sbjct: 123 LDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVF 182 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L VSATD D G N+ +TYS+ A + + F IN +TGAI+ K LDRET Y Sbjct: 183 LTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYT 235 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 LTV A+DGG P L+ TT V I V D NDN PV + + ++ E A + T V+ V A+D Sbjct: 236 LTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDK 295 Query: 609 DVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D+G NGR+ Y ++ G F I D +SG I L + + DGG+P Sbjct: 296 DIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPAL 353 Query: 668 SSTVIVHIKI 677 S +V I + Sbjct: 354 KSRAMVVIDV 363 Score = 144 bits (349), Expect = 9e-34 Identities = 120/391 (30%), Positives = 181/391 (46%), Gaps = 34/391 (8%) Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQIN 458 Y I G G F I + G I++A L + Q Y++ V+ TD G + AMV I+ Sbjct: 2 YSIESG-AHGHFRIKDSSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVID 59 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLSSEISNEAV 517 +T P N Y SV E V+ + +S ++ T+ SS Sbjct: 60 VT------PKPRNLTYDVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDSS------- 105 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F IN T + LDRET + ++L ++ +GG ++ V ++V+D+ND Sbjct: 106 ---GSMFSING-TNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDE 159 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P+F+ + ++ E +GT V ATD D G N + Y + EEG F I+ +G Sbjct: 160 TPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTG 218 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 I K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV + + +S Sbjct: 219 AISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLS 278 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 E + I T + + A D D G N + YSI+ G + F ++ S L M L Y Sbjct: 279 ETAEIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAISLAGM--LSY- 333 Query: 758 SPRKKYELVIR---AASPPLWNDVRVEILVT 785 + R Y +V+ SP L + V I VT Sbjct: 334 NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 364 Score = 138 bits (335), Expect = 4e-32 Identities = 86/262 (32%), Positives = 133/262 (50%), Gaps = 12/262 (4%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G + + LDRE A++ + + T+ + + + VN++D ND P Sbjct: 108 MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 161 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 162 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 219 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P ++ Q S+SE Sbjct: 220 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 279 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 I + V A D D G N L Y++ + G+ + D SG + +G L Sbjct: 280 TAEIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFQIK---DSSSGAISLAGMLSYNQ 335 Query: 329 QAKYQLLVTATDGGDPPRSATA 350 + Y ++V TDGG P + A Sbjct: 336 RNNYIVVVNVTDGGSPALKSRA 357 Score = 135 bits (326), Expect = 6e-31 Identities = 118/396 (29%), Positives = 178/396 (44%), Gaps = 34/396 (8%) Query: 90 FRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 FRI D SGA+ L + Y V+V TD SP L S A + +++ P Sbjct: 12 FRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAMVVIDVT------P 62 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 + TY VSV E + N + +K ++ + + + M FSI+ + Sbjct: 63 KPRNLTYDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLR 117 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 V LD E + L I +GG + ++ +N+ D+ND P F + F SV+E Sbjct: 118 VGST-PLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNE 174 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 +G + V A D D G N+ LTY++ GN + +I+ ++G + + QLDRET Sbjct: 175 IERLGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRET 230 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 + +Y L V A DGG+PP ++T +V L+E TPV T+ Sbjct: 231 RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATV 290 Query: 389 TATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 A+D D + RL Y I G G F I + G I++A L + Q Y++ V+ TD Sbjct: 291 IASDKDIGANGRLMYSIESG-AHGHFQI-KDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 348 Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480 G + AMV I++T P N Y SV E Sbjct: 349 GSPALKSRAMVVIDVT------PKPRNLTYDVSVLE 378 Score = 120 bits (290), Expect = 1e-26 Identities = 80/238 (33%), Positives = 118/238 (49%), Gaps = 26/238 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I Sbjct: 151 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 202 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 203 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 248 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST + + + D NDN P + VS+ E + D PV A + A+D D+GAN + Y+ Sbjct: 249 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI-DTPV-ATVIASDKDIGANGRLMYS 306 Query: 191 IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I G F I DS SG +SL L Y Q +Y +V+ DGGSP+ + ++I++ Sbjct: 307 IESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 363 Score = 115 bits (276), Expect = 6e-25 Identities = 98/358 (27%), Positives = 161/358 (44%), Gaps = 23/358 (6%) Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 H + + +GAI+ +L + Y++ V DGG P+L V V+DV P Sbjct: 9 HGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---P 62 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 + Y +++E V + ++ ++G D GS + + Sbjct: 63 KPRNLTYDVSVLEGE-ANVQVMDLKPAESHFNVSGGNFTFFD----SSGSMFSINGTNLR 117 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 + LDRE+ A H L +GGT V V + + DIND P+F+S ++E Sbjct: 118 VGSTPLDRETAAQHILDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEI 175 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 +GT + A D D G N+ + YSI G++ FS+ + G+ + LD E+ Sbjct: 176 ERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET- 230 Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816 R +Y L + A PPL + V I V D NDN PV++D I + + P V Sbjct: 231 RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATV 290 Query: 817 PAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 A D D+ +L Y I SG + + + + ++G+++L+ L+ N + V+VTDG Sbjct: 291 IASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 348 >SB_44524| Best HMM Match : Cadherin (HMM E-Value=0) Length = 630 Score = 173 bits (422), Expect = 1e-42 Identities = 148/562 (26%), Positives = 248/562 (44%), Gaps = 31/562 (5%) Query: 207 GDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 G ++ TLD+E R + LVI ++ + + + + D ND+AP+F L+ Sbjct: 80 GTLTTKATLDHEDKRGNVFNLVIVRRELSRREGGSVIIVSVIVLDRNDHAPKFPKDLYNA 139 Query: 265 SVSENVPIGYSIVRVQ---AYDADEGVNAELTYTMTDKDYTG--NVDLPITIDPRSGWVY 319 V+EN P G ++ ++ A D D GVNA TYT+ + + G VD+ + + Sbjct: 140 YVAENKPAGTFVLGLEDVYAGDLDSGVNAAYTYTIVEGNKEGLFAVDVNELGGVQFLRLR 199 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 T+ +DRE A + L V TD G P S+T F P YE+ + E+ Sbjct: 200 TTAAIDREKTAFFVLTVQVTDHGKPRMSSTTQVRINILDENDCAPVFDPQIYEISVNENA 259 Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 G+ VV + A DAD + + F I S G+++V ++F++ + + Sbjct: 260 AIGSSVVHVKAVDADAGSNADVYYFFTHDHDFFMINSHT--GVVSVTSHINFEKGNYFEI 317 Query: 440 TVSATDSGGRSDTA--MVQINITDANNY---------APVFENAPYTASVFEDAPIGTTV 488 V+A D G A +V+I + + + + P+F+ + Y + ED P+ + Sbjct: 318 RVAAVDRGRNPHNASTLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAF 377 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L + +A++TY LS +A D F INP++G IT K LD ET Y Sbjct: 378 LHLRIKGDVEDNHARVTYELS------PIALRD-VFAINPKSGVITLRKPLDYETRKTYS 430 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDN--EPVFKQQLYTANIMEDALVGTSVSQVGAT 606 + V A D + T++ I V DV++N P F+ ++ +DA T ++ V AT Sbjct: 431 IKVIALDNRHQTFFAETEITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVSAT 490 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G G + Y + G F + GVI +L+R+ +DL A D P Sbjct: 491 DGDSGREGEVRYHI-VGGSGAGLFALHETGGVITPYGSLNRDH-KRYDLYIEARDNAKNP 548 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +++ + I + N+ P F + + ENS T + + + + YSI Sbjct: 549 RTARLYALILADAKNEKRPFFFAPTQIAEVRENSEESETFVTVVRAEFKGKDSKQMRYSI 608 Query: 727 KGGDDSNSFSLETRQGSDKAEL 748 G++ F++ G E+ Sbjct: 609 SAGNEEGKFTISPETGECFVEI 630 Score = 169 bits (412), Expect = 2e-41 Identities = 143/508 (28%), Positives = 238/508 (46%), Gaps = 38/508 (7%) Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 +VE+ E PGT ++TL D Y + ++R +S+ G +T LD Sbjct: 37 KVEVFEGTEPGTVLLTL-----DRIPGFEY-VLQDSSRDSYSLFHITPDGTLTTKATLDH 90 Query: 432 KQERRYV--LTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + +R V L + + R +V + + D N++AP F Y A V E+ P GT Sbjct: 91 EDKRGNVFNLVIVRRELSRREGGSVIIVSVIVLDRNDHAPKFPKDLYNAYVAENKPAGTF 150 Query: 488 VLV---VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 VL V A D D G+NA TY++ E + E + D + Q + T +DRE Sbjct: 151 VLGLEDVYAGDLDSGVNAAYTYTIV-EGNKEGLFAVDVNELGGVQFLRLRTTAAIDREKT 209 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + ++LTV D G P +S TT V I+++D ND PVF Q+Y ++ E+A +G+SV V Sbjct: 210 AFFVLTVQVTDHGKPRMSSTTQVRINILDENDCAPVFDPQIYEISVNENAAIGSSVVHVK 269 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A DAD G N ++Y + F+I+ +GV+ ++ E +++ A+D G Sbjct: 270 AVDADAGSNADVYYFF---THDHDFFMINSHTGVVSVTSHINFEKGNYFEIRVAAVDRGR 326 Query: 665 PPQSSTVIVHIKIED---------INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 P +++ +V I++ + I+ SPP+F+ I E+ P+ + +R Sbjct: 327 NPHNASTLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAFLHLRIKGDV 386 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772 E +A V Y + + F++ + G + LDYE+ RK Y + + A Sbjct: 387 EDNHARVTYELSPIALRDVFAINPKSG----VITLRKPLDYET-RKTYSIKVIALDNRHQ 441 Query: 773 PLWNDVRVEILVTDVNDN--APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQ 828 + + + I VTDV++N P + F ++ + +D V A D D +++ Sbjct: 442 TFFAETEITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVSATDGDSGREGEVR 501 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLN 856 Y I+ G+ A L L+ET G +T LN Sbjct: 502 YHIVGGSGAGLFALHETGGVITPYGSLN 529 Score = 169 bits (410), Expect = 4e-41 Identities = 155/565 (27%), Positives = 247/565 (43%), Gaps = 44/565 (7%) Query: 97 GALLTRASLDRE-KVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 G L T+A+LD E K LV + S S + V ++D ND+ P+F + Y Sbjct: 80 GTLTTKATLDHEDKRGNVFNLVIVRRELSRREG--GSVIIVSVIVLDRNDHAPKFPKDLY 137 Query: 156 TVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSID-SLSGDVSLVK 213 V E+ + + + A D D G N+A Y I+ GN + F++D + G V ++ Sbjct: 138 NAYVAENKPAGTFVLGLEDVYAGDLDSGVNAAYTYTIVEGNKEGLFAVDVNELGGVQFLR 197 Query: 214 -----TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +D E+ + L ++ D G P S+TTQ+ INI D ND AP F +++ SV+E Sbjct: 198 LRTTAAIDREKTAFFVLTVQVTDHGKPRMSSTTQVRINILDENDCAPVFDPQIYEISVNE 257 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 N IG S+V V+A DAD G NA++ Y T D D+ I+ +G V + ++ E Sbjct: 258 NAAIGSSVVHVKAVDADAGSNADVYYFFTHDHDF-------FMINSHTGVVSVTSHINFE 310 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXX---------XXXXXXXXFMPGQYEVELAED 378 +++ V A D G P +A+ F +Y V++ ED Sbjct: 311 KGNYFEIRVAAVDRGRNPHNASTLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIRED 370 Query: 379 EPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 P + + L EDN R+ YE++ R F+I ++ G+IT+ +PLD++ + Sbjct: 371 LPVNSAFLHLRIKGDVEDNHARVTYELSPIALRDVFAINPKS--GVITLRKPLDYETRKT 428 Query: 437 YVLTVSATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 Y + V A D+ ++ A +I I D N + P FE+ + +DA T + VS Sbjct: 429 YSIKVIALDNRHQTFFAETEITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVS 488 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 ATD D G ++ Y + A H+ VI P +K D L + Sbjct: 489 ATDGDSGREGEVRYHIVGGSGAGLFALHETGGVITPYGSLNRDHKRYD--------LYIE 540 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 ARD + I N+ P F A + E++ + V + Sbjct: 541 ARDNAKNPRTARLYALILADAKNEKRPFFFAPTQIAEVRENSEESETFVTVVRAEFKGKD 600 Query: 613 NGRIHYELDPKDREEGSFVIDPASG 637 + ++ Y + EEG F I P +G Sbjct: 601 SKQMRYSIS-AGNEEGKFTISPETG 624 Score = 158 bits (384), Expect = 5e-38 Identities = 156/537 (29%), Positives = 250/537 (46%), Gaps = 52/537 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIELVTADT 69 VLD NDH+P F Y A V E +GT VL L+ A D D G NA YTI V Sbjct: 122 VLDRNDHAPKFPKDLYNAYVAENKPAGTFVLGLEDVYAGDLDSGVNAAYTYTI--VEG-- 177 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E VQ + L T A++DREK A + + V+ TD P R Sbjct: 178 -NKEGLFAVDVNELGGVQFL--------RLRTTAAIDREKTAFFVLTVQVTDHGKP---R 225 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +SST + +NI+D+ND P F + Y +SV+E+ ++ + + +KA DAD G+N+ + Y Sbjct: 226 MSSTTQVRINILDENDCAPVFDPQIYEISVNENAAIGSS--VVHVKAVDADAGSNADVYY 283 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + F I+S +G VS+ +++E+ + + + A D G + +T + I + + Sbjct: 284 FFT--HDHDFFMINSHTGVVSVTSHINFEKGNYFEIRVAAVDRGRNPHNASTLVKIRLLE 341 Query: 250 VN--DNAPRFYTS--LFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 V+ PR +TS +FQ S + E++P+ + + ++ E +A +TY ++ Sbjct: 342 VDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAFLHLRIKGDVEDNHARVTYELSP-- 399 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA--TXXXXXXX 358 D+ I+P+SG + LD ET+ Y + V A D A T Sbjct: 400 -IALRDV-FAINPKSGVITLRKPLDYETRKTYSIKVIALDNRHQTFFAETEITIEVTDVD 457 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416 F L +D T + T++ATD D + + Y I GG+ G F++ Sbjct: 458 ENYFTPEFESFTVLGHLPQDADARTLIATVSATDGDSGREGEVRYHIVGGSGAGLFAL-H 516 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA-MVQINITDANNYAPVFENAP-Y 474 + G G+IT L+ + +RY L + A D+ TA + + + DA N F AP Sbjct: 517 ETG-GVITPYGSLN-RDHKRYDLYIEARDNAKNPRTARLYALILADAKNEKRPFFFAPTQ 574 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 A V E++ T + V + + Q+ YS+S+ NE + +F I+P+TG Sbjct: 575 IAEVRENSEESETFVTVVRAEFKGKDSKQMRYSISA--GNE-----EGKFTISPETG 624 Score = 116 bits (280), Expect = 2e-25 Identities = 110/428 (25%), Positives = 182/428 (42%), Gaps = 42/428 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +IN+LD ND +PVF+ Q YE SV E A+ G++V+ +KA D D G NA+V Y T D Sbjct: 233 RINILDENDCAPVFDPQIYEISVNENAAIGSSVVHVKAVDADAGSNADVYY---FFTHD- 288 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 D F I+ +G + + ++ EK + + V A D+ + Sbjct: 289 -----------------HDFFMINSHTGVVSVTSHINFEKGNYFEIRVAAVDRGRNPHNA 331 Query: 130 LSSTATIHVNIIDD-------NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 S+ I + +D + + P F Y V + ED+ V + +IK DV Sbjct: 332 -STLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAFLHLRIKG---DVE 387 Query: 183 ANSA-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 N A + Y + + F+I+ SG ++L K LDYE ++Y + + A D + T Sbjct: 388 DNHARVTYELSPIALRDVFAINPKSGVITLRKPLDYETRKTYSIKVIALDNRHQTFFAET 447 Query: 242 QLLINIRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 ++ I + DV++N P F + + ++ I V A D D G E+ Y + Sbjct: 448 EITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVSATDGDSGREGEVRYHIVGG 507 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 G L T G + G L+R+ +Y L + A D PR+A Sbjct: 508 SGAGLFALHET----GGVITPYGSLNRD-HKRYDLYIEARDNAKNPRTARLYALILADAK 562 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD--ADEDNRLHYEITGGNTRGRFSITSQ 417 F E+ E+ VT+ + + ++ Y I+ GN G+F+I+ + Sbjct: 563 NEKRPFFFAPTQIAEVRENSEESETFVTVVRAEFKGKDSKQMRYSISAGNEEGKFTISPE 622 Query: 418 NGRGLITV 425 G + + Sbjct: 623 TGECFVEI 630 >SB_33995| Best HMM Match : Cadherin (HMM E-Value=3e-39) Length = 632 Score = 165 bits (401), Expect = 5e-40 Identities = 168/615 (27%), Positives = 264/615 (42%), Gaps = 61/615 (9%) Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +S LD E+V Y L +RA+ G+P S S+ Q+++ + D+NDN P F + + Sbjct: 3 ISTTSRLDRERVDRYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYIR 62 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--- 324 EN +++ + A D D G+N+++TYT+ + G + T+ S + L Sbjct: 63 ENQGTIPNLLCLIASDKDIGLNSDITYTIESGNDDGLFAIHPTLGILSEIIRLREDLGAR 122 Query: 325 --DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 D +++Y L P S T G V + ED PG Sbjct: 123 VDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITDEDARHKFGGDNPVSVEEDAEPG 182 Query: 383 TPVVTLTATDADEDNRLHYEIT----GGNTRGRFSI-TSQNGRGLITVAQPLDFKQERRY 437 + + +TD D + T + FS T + G LI + L++ + +Y Sbjct: 183 RTLTIIDSTDEDAGKSGQFVCTIDDVDSDVMDMFSFHTVRQGCALI-LYNHLEYSRRSQY 241 Query: 438 VLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 V A+D S TA V + + D NN P+F+ + Y ++ E +PIGT +L V+A Sbjct: 242 TFKVRASDQADAVQQLSTTANVIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTA 301 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D D G SN V H Q+ + NK Y TVTA Sbjct: 302 EDLDSG-------------SNADVKDHYLQY-------QASRNKK--------YSFTVTA 333 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D G PS S V +S+ +D+ PVF++ Y I E+ + + +V A G Sbjct: 334 FDQGKPSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAG 393 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID----GGTPPQSS 669 G + Y L D + F +D +G + K LD E VA++ L+ A+ P + Sbjct: 394 GELRYYLVGGD-PQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPA 452 Query: 670 TVIVHIKIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 V I + DIND+ P F + L I + P GTT+ ++ A+D D G +A+V Y ++ Sbjct: 453 EATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLE 512 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWN-DVRVEILV 784 DS F++ + G K T +L + R Y V+ A ++PP V + V Sbjct: 513 NA-DSFPFTITPQTGVIK----TTAELRH-FERDFYAFVVTATDSTPPFHKVTANVNVHV 566 Query: 785 TDVNDNAPVMKDFQI 799 TD PV +I Sbjct: 567 TDAR-TPPVFTKVRI 580 Score = 161 bits (391), Expect = 7e-39 Identities = 165/608 (27%), Positives = 249/608 (40%), Gaps = 68/608 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ PVF + +RE + +L L A+D+DIG N+++ YTIE Sbjct: 40 VMVTDMNDNRPVFANTNHTVYIRENQGTIPNLLCLIASDKDIGLNSDITYTIES------ 93 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D + ++ R+ GA + D K +RY L + P S ++ Sbjct: 94 GNDDGLFAIHPTLGILSEIIRLREDLGARVD----DTSKRSRYPELEQYCALNVPDSSKI 149 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + I V I D D +F VSV+ED + I +TD D G + Sbjct: 150 RTI--IAVLEITDEDARHKFGGDN-PVSVEEDAE--PGRTLTIIDSTDEDAGKSGQFVCT 204 Query: 191 I--IGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLL 244 I + + FS ++ +L+ L+Y + Y +RA D + S T ++ Sbjct: 205 IDDVDSDVMDMFSFHTVRQGCALILYNHLEYSRRSQYTFKVRASDQADAVQQLSTTANVI 264 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D N+N P F S + ++ E PIG ++RV A D D G NA++ KD+ Sbjct: 265 VRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADV------KDH--- 315 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 Y Q R KY VTA D G P RS+ AT Sbjct: 316 --------------YLQYQASRNK--KYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPP 359 Query: 365 XFMPGQYEVELAEDEP--PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F YE + E+ G V A L Y + GG+ + +F++ G Sbjct: 360 VFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVGGDPQSQFNVDRLTGE-- 417 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDT------AMVQINITDANNYAPVFE--NAPY 474 +++ +PLD+++ Y L + A R + A V I +TD N+ AP F P Sbjct: 418 LSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPREPL 477 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 S+ + P GTTV V+A D D G +A + Y L + S F I PQTG I Sbjct: 478 VTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENADSFP--------FTITPQTGVIK 529 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMED 593 T L Y VTA D P T +V + V D PVF K ++ I Sbjct: 530 TTAELRHFERDFYAFVVTATDSTPPFHKVTANVNVHVTDAR-TPPVFTKVRIAVITITTT 588 Query: 594 ALVGTSVS 601 + T+++ Sbjct: 589 ITITTTIT 596 Score = 147 bits (355), Expect = 2e-34 Identities = 158/607 (26%), Positives = 253/607 (41%), Gaps = 56/607 (9%) Query: 101 TRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVD 160 T + LDRE+V RY + V+A +P S +SS A + V + D NDN P F+ +TV + Sbjct: 5 TTSRLDRERVDRYALEVRARVNGAPQS--MSSPAQVVVMVTDMNDNRPVFANTNHTVYIR 62 Query: 161 EDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS--------LV 212 E+ N + + A+D D+G NS I Y I GN F+I G +S L Sbjct: 63 ENQGTIPN--LLCLIASDKDIGLNSDITYTIESGNDDGLFAIHPTLGILSEIIRLREDLG 120 Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVP 271 +D RS + + S+ + +I + ++ D R + SV E+ Sbjct: 121 ARVDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITDEDARHKFGGDNPVSVEEDAE 180 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQA 330 G ++ + + D D G + + T+ D D + +D+ R G + L+ ++ Sbjct: 181 PGRTLTIIDSTDEDAGKSGQFVCTIDDVD-SDVMDMFSFHTVRQGCALILYNHLEYSRRS 239 Query: 331 KYQLLVTATDGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 +Y V A+D D + S TA F Y V L E P GT ++ + Sbjct: 240 QYTFKVRASDQADAVQQLSTTANVIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRV 299 Query: 389 TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG- 447 TA D D +G N + + ++Y TV+A D G Sbjct: 300 TAEDLD---------SGSNADVKDHYLQYQA------------SRNKKYSFTVTAFDQGK 338 Query: 448 -GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 RS A V ++I ++ PVF + Y + E+ + ++ V A + G ++ Y Sbjct: 339 PSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRY 398 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD----GGVPSLS 562 L QF ++ TG ++ K LD E ++ Y L + A +P L Sbjct: 399 YLVG-------GDPQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELP 451 Query: 563 DTTDVEISVVDVNDNEPVF--KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 V I+V D+NDN P F ++ +I + GT+V++V A D D G + + Y L Sbjct: 452 AEATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGL 511 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 + D F I P +GVI+T L + A D P T V++ + D Sbjct: 512 ENAD--SFPFTITPQTGVIKTTAELRHFERDFYAFVVTATDSTPPFHKVTANVNVHVTDA 569 Query: 681 NDSPPVF 687 +PPVF Sbjct: 570 R-TPPVF 575 Score = 121 bits (292), Expect = 7e-27 Identities = 132/496 (26%), Positives = 219/496 (44%), Gaps = 62/496 (12%) Query: 31 SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVF 90 SV E A G T+ + +TD+D GK+ + TI+ V +D V D+F Sbjct: 174 SVEEDAEPGRTLTIIDSTDEDAGKSGQFVCTIDDVDSD-----------------VMDMF 216 Query: 91 RIDG-RSG-ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 R G AL+ L+ + ++YT V+A+DQA V +LS+TA + V ++D N+N P Sbjct: 217 SFHTVRQGCALILYNHLEYSRRSQYTFKVRASDQADAVQ-QLSTTANVIVRVLDGNNNDP 275 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F + +Y V++ E + + ++ A D D G+N+ ++ + Q Q S + Sbjct: 276 IFQQSSYWVALPEGSPIGTE--LLRVTAEDLDSGSNADVKDHYL----QYQASRN----- 324 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + Y + A D G PSRS+ + ++I +D+ P F S +++ + E Sbjct: 325 ------------KKYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPE 372 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N + IVRV+A G EL Y + G+ +D +G + LD E Sbjct: 373 NFALKRGIVRVEALANGGGAGGELRYYLVG----GDPQSQFNVDRLTGELSLKKPLDYEK 428 Query: 329 QAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEV-ELAEDEPPG 382 A Y+L + A P A AT F +P + V + + P G Sbjct: 429 VASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAG 488 Query: 383 TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 T V +TA D D + + Y + ++ F+IT Q G + T A+ F+++ Y Sbjct: 489 TTVTKVTAYDQDSGSHALVKYGLENADS-FPFTITPQTG-VIKTTAELRHFERD-FYAFV 545 Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA-SVFEDAPIGTTVLVVSATDSD 497 V+ATDS TA V +++TDA PVF ++ I TT+ + + Sbjct: 546 VTATDSTPPFHKVTANVNVHVTDART-PPVFTKVRIAVITITTTITITTTITITTTITIT 604 Query: 498 VGINAQITYSLSSEIS 513 + I IT +++ I+ Sbjct: 605 ITITITITITITITIT 620 Score = 94.3 bits (224), Expect = 1e-18 Identities = 88/324 (27%), Positives = 151/324 (46%), Gaps = 30/324 (9%) Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASV 478 +I+ LD ++ RY L V A +G S A V + +TD N+ PVF N +T + Sbjct: 2 VISTTSRLDRERVDRYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYI 61 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ +L + A+D D+G+N+ ITY++ S + D F I+P G I + + Sbjct: 62 RENQGTIPNLLCLIASDKDIGLNSDITYTIES-------GNDDGLFAIHPTLG-ILSEII 113 Query: 539 LDRETMSGYLLTVTARDGGVPSLS--------DTTDVE--ISVVDVNDNEPVFK-QQLYT 587 RE + G + T++ P L D++ + I+V+++ D + K Sbjct: 114 RLREDL-GARVDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITDEDARHKFGGDNP 172 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSF--VIDPASGVIRTN 642 ++ EDA G +++ + +TD D G +G+ +D D + SF V + ++ + Sbjct: 173 VSVEEDAEPGRTLTIIDSTDEDAGKSGQFVCTIDDVDSDVMDMFSFHTVRQGCALILYNH 232 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 R S T ++A S+T V +++ D N++ P+F+ + E SPI Sbjct: 233 LEYSRRSQYTFKVRASDQADAVQQLSTTANVIVRVLDGNNNDPIFQQSSYWVALPEGSPI 292 Query: 703 GTTIGEIRAHDPDEGPNAVV--HY 724 GT + + A D D G NA V HY Sbjct: 293 GTELLRVTAEDLDSGSNADVKDHY 316 Score = 59.3 bits (137), Expect = 4e-08 Identities = 47/160 (29%), Positives = 79/160 (49%), Gaps = 9/160 (5%) Query: 638 VIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 VI T LDRE V + L+ A ++G SS V + + D+ND+ PVF + T YI Sbjct: 2 VISTTSRLDRERVDRYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYI 61 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD--- 753 EN + + A D D G N+ + Y+I+ G+D F++ G +E++ + + Sbjct: 62 RENQGTIPNLLCLIASDKDIGLNSDITYTIESGNDDGLFAIHPTLGI-LSEIIRLREDLG 120 Query: 754 --LDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVND 789 +D S R +Y + + A + P + +R I V ++ D Sbjct: 121 ARVDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITD 160 Score = 31.9 bits (69), Expect = 7.6 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 762 KYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817 +Y L +RA A + + +V ++VTD+NDN PV + ++ + + Sbjct: 16 RYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYIRENQGTIPNLLCLI 75 Query: 818 AYDADV--TDKLQYRILSGNNANLILLNETTGSMT 850 A D D+ + Y I SGN+ L ++ T G ++ Sbjct: 76 ASDKDIGLNSDITYTIESGNDDGLFAIHPTLGILS 110 >SB_39408| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2389 Score = 165 bits (400), Expect = 6e-40 Identities = 115/346 (33%), Positives = 169/346 (48%), Gaps = 30/346 (8%) Query: 463 NNYAPVFE--NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 N++AP F N Y A++ E+ GT VL VSA D D G + +++ S + Sbjct: 2040 NDFAPEFVPINPNYQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIYS-------GNT 2092 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNE 578 D F I+ ++G I T + LDRE +S Y LT+ ARD TD +SV+ DVNDN Sbjct: 2093 DNSFAIDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNS 2152 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 PVF Y A + E A VG ++ + ATD D G N R+HY + E+G F I+ +G Sbjct: 2153 PVFSHDEYRALVKETARVGEAIIRARATDRDAGTNARLHYTI-TSGNEQGLFAINDETGD 2211 Query: 639 IRTNKALDRESVA----THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE---SDC 691 + K LD E A + L D G+PP+ ++ VHI++ +N+ P+F S Sbjct: 2212 VTVAKPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRN 2271 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 LT + +G + ++ A D D G V Y+I G+ + F ++ + + Sbjct: 2272 LTIREHLDVGLGLALIDLDAKDKDYGIQGHVSYAIYSGNQAGMFRVDA-----NGTVYLL 2326 Query: 752 VDLDYESPRKKYELVIRAASPPLWN-----DVRVEILVTDVNDNAP 792 LDY + Y LVIRA D + +LV D+NDNAP Sbjct: 2327 GTLDY-ARAPSYRLVIRATDGGAKEMRKHADFTLTVLVEDINDNAP 2371 Score = 157 bits (382), Expect = 9e-38 Identities = 111/335 (33%), Positives = 168/335 (50%), Gaps = 36/335 (10%) Query: 17 NDHSPVFEM--QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 ND +P F Y+A++ E ++GT VLT+ A D D G +V +TI D Sbjct: 2040 NDFAPEFVPINPNYQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIYSGNTD------ 2093 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 + F ID RSG + TR +LDRE ++ Y + ++A D A R + A Sbjct: 2094 -------------NSFAIDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTD-A 2139 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + V + D NDN P FS Y V E V + I + +ATD D G N+ + Y I G Sbjct: 2140 LVSVIVSDVNDNSPVFSHDEYRALVKETARVGE--AIIRARATDRDAGTNARLHYTITSG 2197 Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQ----VRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 N Q F+I+ +GDV++ K LD E +YRL + D GSP R N+T + I + V Sbjct: 2198 NEQGLFAINDETGDVTVAKPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPV 2257 Query: 251 NDNAPRFYTSLFQE-SVSE--NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 N+ +P F + + ++ E +V +G +++ + A D D G+ ++Y + Y+GN Sbjct: 2258 NEFSPIFRRGVSRNLTIREHLDVGLGLALIDLDAKDKDYGIQGHVSYAI----YSGNQAG 2313 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 +D +G VY G LD Y+L++ ATDGG Sbjct: 2314 MFRVD-ANGTVYLLGTLDYARAPSYRLVIRATDGG 2347 Score = 143 bits (346), Expect = 2e-33 Identities = 109/347 (31%), Positives = 170/347 (48%), Gaps = 26/347 (7%) Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y+ L E+ GT V+T++A D D+ ++ + + I GNT F+I ++G +I + Sbjct: 2053 YQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIYSGNTDNSFAIDDRSG--VIKTRRT 2110 Query: 429 LDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 LD + Y LT+ A D R A+V + ++D N+ +PVF + Y A V E A + Sbjct: 2111 LDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNSPVFSHDEYRALVKETARV 2170 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE-- 542 G ++ ATD D G NA++ Y+++S NE F IN +TG +T K LD E Sbjct: 2171 GEAIIRARATDRDAGTNARLHYTITS--GNE-----QGLFAINDETGDVTVAKPLDLEDG 2223 Query: 543 --TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL-YTANIME--DALVG 597 T Y L V D G P ++T V I V VN+ P+F++ + I E D +G Sbjct: 2224 ALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRNLTIREHLDVGLG 2283 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 ++ + A D D G+ G + Y + + G F +D A+G + LD ++ L Sbjct: 2284 LALIDLDAKDKDYGIQGHVSYAI-YSGNQAGMFRVD-ANGTVYLLGTLDYARAPSYRLVI 2341 Query: 658 VAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 A DGG + + + + +EDIND+ P F SD + E S I Sbjct: 2342 RATDGGAKEMRKHADFTLTVLVEDINDNAPKFASDKTMVDVYETSKI 2388 Score = 136 bits (328), Expect = 3e-31 Identities = 107/358 (29%), Positives = 157/358 (43%), Gaps = 26/358 (7%) Query: 144 NDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201 ND P+F Y ++ E+ T + + A D D G+ + + I GNT F+ Sbjct: 2040 NDFAPEFVPINPNYQATLLEN--TTTGTQVLTVSAVDHDKGSQGDVFFTIYSGNTDNSFA 2097 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN--IRDVNDNAPRFYT 259 ID SG + +TLD E + Y L IRA+D + T L++ + DVNDN+P F Sbjct: 2098 IDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNSPVFSH 2157 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 ++ V E +G +I+R +A D D G NA L YT+T +GN I+ +G V Sbjct: 2158 DEYRALVKETARVGEAIIRARATDRDAGTNARLHYTIT----SGNEQGLFAINDETGDVT 2213 Query: 320 TSGQLDRE----TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG-QYEVE 374 + LD E T Y+L V TD G PPR + T F G + Sbjct: 2214 VAKPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRNLT 2273 Query: 375 LAE--DEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + E D G ++ L A D D + H Y I GN G F + + G + + LD Sbjct: 2274 IREHLDVGLGLALIDLDAKDKDYGIQGHVSYAIYSGNQAGMFRV---DANGTVYLLGTLD 2330 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDAPI 484 + + Y L + ATD G + +T D N+ AP F + V+E + I Sbjct: 2331 YARAPSYRLVIRATDGGAKEMRKHADFTLTVLVEDINDNAPKFASDKTMVDVYETSKI 2388 Score = 120 bits (290), Expect = 1e-26 Identities = 89/263 (33%), Positives = 124/263 (47%), Gaps = 22/263 (8%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND+SPVF +Y A V+E A G ++ +ATD+D G NA + YTI T Sbjct: 2145 VSDVNDNSPVFSHDEYRALVKETARVGEAIIRARATDRDAGTNARLHYTI------TSGN 2198 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 E V +D GAL + A Y + V TDQ SP R +S Sbjct: 2199 EQGLFAINDETGDVTVAKPLDLEDGALTSLA---------YRLGVYVTDQGSP--PRGNS 2247 Query: 133 TATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 T T+H+ + N+ P F + +++ E + V + + A D D G + YAI Sbjct: 2248 T-TVHIQVTPVNEFSPIFRRGVSRNLTIREHLDVGLGLALIDLDAKDKDYGIQGHVSYAI 2306 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LLINIRD 249 GN F +D+ +G V L+ TLDY + SYRLVIRA DGG+ L + + D Sbjct: 2307 YSGNQAGMFRVDA-NGTVYLLGTLDYARAPSYRLVIRATDGGAKEMRKHADFTLTVLVED 2365 Query: 250 VNDNAPRFYTSLFQESVSENVPI 272 +NDNAP+F + V E I Sbjct: 2366 INDNAPKFASDKTMVDVYETSKI 2388 Score = 115 bits (276), Expect = 6e-25 Identities = 95/334 (28%), Positives = 150/334 (44%), Gaps = 22/334 (6%) Query: 574 VNDNEPVFK--QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 VND P F Y A ++E+ GT V V A D D G G + + + + SF Sbjct: 2039 VNDFAPEFVPINPNYQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIY-SGNTDNSFA 2097 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFES 689 ID SGVI+T + LDRE ++ ++L A D + + +V + + D+ND+ PVF Sbjct: 2098 IDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNSPVFSH 2157 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 D + E + +G I RA D D G NA +HY+I G++ F++ G + Sbjct: 2158 DEYRALVKETARVGEAIIRARATDRDAGTNARLHYTITSGNEQGLFAINDETGD--VTVA 2215 Query: 750 TMVDL-DYESPRKKYEL---VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805 +DL D Y L V SPP N V I VT VN+ +P+ + + Sbjct: 2216 KPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRNLTIR 2275 Query: 806 DCFPVGPFGRVPAYDADVTDK-------LQYRILSGNNANLILLNETTGSMTLSPQLNTN 858 + VG G + D D DK + Y I SGN A + + + G++ L L+ Sbjct: 2276 EHLDVG-LG-LALIDLDAKDKDYGIQGHVSYAIYSGNQAGMFRV-DANGTVYLLGTLDYA 2332 Query: 859 VPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEM 891 + + TD G E++ ++ ++ E++ Sbjct: 2333 RAPSYRLVIRATDGGAKEMRKHADFTLTVLVEDI 2366 >SB_34907| Best HMM Match : Cadherin (HMM E-Value=0) Length = 697 Score = 162 bits (393), Expect = 4e-39 Identities = 162/563 (28%), Positives = 247/563 (43%), Gaps = 67/563 (11%) Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIG 193 T+ + + D N+ P F Y + E+ + T + K A D D + RY I+ Sbjct: 117 TLRITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGLEKCHAEDKD--RSGIDRYEIVS 174 Query: 194 GNTQMQFSIDSLSGDVS---LVKTLDYEQVR-----SYRLVIRAQDGGSPSRSNTTQLLI 245 GN + F ++ + ++K + VR S L +RA DGG TT++ I Sbjct: 175 GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVRANDGGG--LHGTTRIQI 232 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 +I+D N+N P F S + +V E+ P+ SI+RV+A DAD G N + Y Y N Sbjct: 233 DIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYY------YLRNT 286 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX----------- 354 TID +G + LD ++ + L VTA D G P++A Sbjct: 287 Q-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIRSDISGYPP 345 Query: 355 ----XXXXXXXXXXXFMPG-QYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGG 406 F G + + + ED P + + A D D + +L Y ++G Sbjct: 346 VVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQLRYSLSGN 405 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDTAMVQINI---- 459 N F+I S + G++T+ L++K + L V+ATD G+S +N+ Sbjct: 406 N---NFAIDSTS--GVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVNLKIEV 460 Query: 460 --TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 D NN APVF +V ED+ +G T+ VSATDSD G + Q+ YS+ I + Sbjct: 461 LDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSI---IQGSGL 517 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F + TG + LDRE MS Y L + A D S V + + DV+D+ Sbjct: 518 G----VFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDH 573 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F Q +Y A E + T V+ V D D+G + + Y + SF I P SG Sbjct: 574 FPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSI----TGASSFKIVPTSG 627 Query: 638 VIRTNKALD-RESVATHDLKAVA 659 +I T +D +T++L A Sbjct: 628 LILTTGPIDLTTEPSTYELVVTA 650 Score = 156 bits (378), Expect = 3e-37 Identities = 156/582 (26%), Positives = 259/582 (44%), Gaps = 60/582 (10%) Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 Y L + + G L I + D N+ P F L+ ++E G ++ ++ Sbjct: 98 YVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGLEKC 157 Query: 283 DADEGVNAEL-TYTMTDKDYTGN-VDLPITIDPRSGWVY--TSGQLDRE-TQAKYQLLVT 337 A++ + + Y + + G V T+ + V T+ ++ R+ + L V Sbjct: 158 HAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVR 217 Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--E 395 A DGG T F +Y V + ED P T ++ + A DAD Sbjct: 218 ANDGGG--LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGR 275 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455 + ++Y + NT+ F+I + G+I + LDF+ ++ L V+A D G A V Sbjct: 276 NGGIYYYLR--NTQD-FTIDAIT--GVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANV 330 Query: 456 QINIT---DANNYAPVF---------------ENAPYTASVFEDAPIGTTVLVVSATDSD 497 + +T D + Y PV E + +T S+ ED P+ + VV A D D Sbjct: 331 NVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPD 390 Query: 498 VG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLTV 551 G N Q+ YSLS + F I+ +G +T L+ + + ++T Sbjct: 391 AGSTNGQLRYSLSG----------NNNFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTA 440 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 T R+G +LS + +++I V+DV+DN PVF Q + ED+ VG ++ +V ATD+D Sbjct: 441 TDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSD 500 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G +G++ Y + + G F + +G + LDRE ++ +DL A D T P+SS Sbjct: 501 DGSDGQVVYSI-IQGSGLGVFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSS 559 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + V +KI+D++D P F E SP T + ++ D D G + V YSI G Sbjct: 560 NLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITG- 616 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 ++SF + G ++T +D + YELV+ A S Sbjct: 617 --ASSFKIVPTSGL----ILTTGPIDLTTEPSTYELVVTATS 652 Score = 155 bits (375), Expect = 6e-37 Identities = 148/515 (28%), Positives = 235/515 (45%), Gaps = 50/515 (9%) Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK--Q 433 E+EP G V + + ++E + T + R S++G ++ PL + + Sbjct: 37 ENEPEGFRVFSFPSPPSNEIYSFFRALDTASQSALRLFDISEDG--VVVTKNPLVYTDGE 94 Query: 434 ERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 E YVLTV G ++I +TD NN+ P F Y + E+A GTTV + Sbjct: 95 ENLYVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGL 154 Query: 492 SATDSDVGINAQIT-YSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGY 547 ++ + I Y + S NE + + Q + T +++ Sbjct: 155 EKCHAEDKDRSGIDRYEIVS--GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSI 212 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LTV A DGG L TT ++I + D N+N PVF++ YT + ED V TS+ +V A D Sbjct: 213 TLTVRANDGG--GLHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARD 270 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 AD+G NG I+Y L R F ID +GVIR + LD +S L+ A D G+ P+ Sbjct: 271 ADIGRNGGIYYYL----RNTQDFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPK 326 Query: 668 SSTVIVHIKIE-DIN--------------DSPPVF-ESDCLTFYISENSPIGTTIGEIRA 711 ++ V V + I DI+ + PPVF E T I E+ P+ I ++A Sbjct: 327 AANVNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKA 386 Query: 712 HDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 +DPD G N + YS+ G +N+F++++ G L T ++ + +LV+ A Sbjct: 387 NDPDAGSTNGQLRYSLSG---NNNFAIDSTSG--VVTLQTQLEYKGNPAQDVIDLVVTAT 441 Query: 771 -----SPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822 S L V ++E+L D N+NAPV Q+ +D RV A D+D Sbjct: 442 DRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDD 501 Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 ++ Y I+ G+ + + TTG + ++ L+ Sbjct: 502 GSDGQVVYSIIQGSGLGVFQVQATTGDLIVAAPLD 536 Score = 151 bits (367), Expect = 6e-36 Identities = 165/574 (28%), Positives = 253/574 (44%), Gaps = 72/574 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-KATDQDIGKNAEVEYTIELVTAD 68 +I V D N+ P F Y + E A+ GTTV L K +D ++ Y E+V+ + Sbjct: 119 RITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGLEKCHAEDKDRSGIDRY--EIVSGN 176 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 E Q + + TR D + + T+ V+A D Sbjct: 177 ----ERGYFVAETKTVGAQKFLVLKATN----TRIVRDPARPS-ITLTVRANDGGG---- 223 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L T I ++I D N+N P F + YTV+V ED V + I +++A DAD+G N I Sbjct: 224 -LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTS--ILRVRARDADIGRNGGIY 280 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + NTQ F+ID+++G + ++ LD++ + L + A+D GS ++ + + IR Sbjct: 281 YYL--RNTQ-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIR 337 Query: 249 -DVND-------------NAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEG-VNAE 291 D++ N P + S F S+ E+ P+ +I V+A D D G N + Sbjct: 338 SDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQ 397 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD---RETQAKYQLLVTATD----GGDP 344 L Y++ +GN + ID SG V QL+ Q L+VTATD G Sbjct: 398 LRYSL-----SGNNN--FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGAL 450 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402 S F P Q E+ ++ED G + ++ATD+D+ D ++ Y Sbjct: 451 SASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYS 510 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINIT 460 I G+ G F + + G + VA PLD ++ Y L + A D +S V + I Sbjct: 511 IIQGSGLGVFQVQATTGD--LIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQ 568 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 D +++ P F Y A E +P T V VV D D+G ++YS++ S Sbjct: 569 DVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGASS------- 619 Query: 521 DQQFVINPQTGAITTNKLLDRET-MSGYLLTVTA 553 F I P +G I T +D T S Y L VTA Sbjct: 620 ---FKIVPTSGLILTTGPIDLTTEPSTYELVVTA 650 Score = 147 bits (356), Expect = 1e-34 Identities = 131/461 (28%), Positives = 208/461 (45%), Gaps = 35/461 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI++ D N++ PVFE +Y +V E T++L ++A D DIG+N + Y + Sbjct: 231 QIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYYYLR------ 284 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N +D ++ + +D +SG T R++ Q + SD Sbjct: 285 -NTQD--FTIDAITGVIRPIRMLDFQSGQQRTLEVTARDR-GSSPKAANVNVQVTIRSDI 340 Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAI 187 + + D + P F E ++T+S+ ED V N I +KA D D G+ N + Sbjct: 341 SGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPV--NGAIQVVKANDPDAGSTNGQL 398 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQD--GGSPSRSNTTQ 242 RY++ G N F+IDS SG V+L L+Y+ + LV+ A D G S + S + Sbjct: 399 RYSLSGNN---NFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVN 455 Query: 243 LLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 L I + DV N+NAP F + +VSE+ +G +I RV A D+D+G + ++ Y++ Sbjct: 456 LKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSIIQGS 515 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G + T +G + + LDRE + Y L++ A D P+S+ Sbjct: 516 GLGVFQVQAT----TGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVD 571 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F Y + E P T V + D D + Y ITG ++ F I + Sbjct: 572 DHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGASS---FKIVPTS-- 626 Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSG-GRSDTAMVQINI 459 GLI P+D E Y L V+AT + G + A Q+N+ Sbjct: 627 GLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNV 667 Score = 36.3 bits (80), Expect = 0.35 Identities = 15/55 (27%), Positives = 25/55 (45%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 ++ + + D +DH P F Y A E + T V +K D D+G++ T Sbjct: 561 LYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSIT 615 >SB_51258| Best HMM Match : Cadherin (HMM E-Value=0) Length = 484 Score = 153 bits (371), Expect = 2e-36 Identities = 114/342 (33%), Positives = 165/342 (48%), Gaps = 30/342 (8%) Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKY---QLLVTATDGGDPPRSATATXXXXXXXXXX 361 V + +T PR+ Y L+ E + +++V TDGG P + A Sbjct: 151 VVIDVTPKPRN-LTYDVSVLEGEANVQVMDLKVVVNVTDGGSPALKSRAMVVIDVTPKPR 209 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQN 418 Y+V + E E V+ L ++ H+ +GG S+ S N Sbjct: 210 NLT------YDVSVLEGEA-NVQVMDLKPAES------HFNASGGTFAFFGSSGSMFSIN 256 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G L + PLD + +VL +S T+ G V +N+ D N+ P F++ + SV Sbjct: 257 GTNLRVGSTPLDRETAEEHVLDISLTEGGIVKGLFKVTVNVLDINDETPSFQSPSFNVSV 316 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E +GT L VSATDSD G N+ +TYS+ A + + F IN +T AI+ K Sbjct: 317 NEIERLGTVFLTVSATDSDAGANSALTYSI-------AAGNEEGFFSINNKTSAISVAKQ 369 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRET Y+LTV A+DGG PSL+ T V I V D NDN PV + + ++ E A + T Sbjct: 370 LDRETRDLYMLTVMAQDGGEPSLNRTAAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDT 429 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVI 639 V+ V A+D D+G NGR+ Y ++ G F I D +SG I Sbjct: 430 PVATVIASDKDIGANGRLLYSIE--SGAHGHFQIKDSSSGAI 469 Score = 124 bits (299), Expect = 1e-27 Identities = 124/450 (27%), Positives = 188/450 (41%), Gaps = 37/450 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PV + S+ E A+ T V T+ A+D+DIG N + Y+IE Sbjct: 48 IQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHF 107 Query: 71 NPEDAXXXXXXXXXXVQDVFR---------IDGRSGALLTRASLDREKVARYTVLVKATD 121 +D+ + R DG S AL +RA + + + L Sbjct: 108 QIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVS 167 Query: 122 QASPVSDRLSSTATIHVNIIDDN------------DNYPQFSEKTYTVSVDEDISVTDNP 169 ++ + VN+ D D P+ TY VSV E + N Sbjct: 168 VLEGEANVQVMDLKVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVSVLEGEA---NV 224 Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 + +K ++ A+ +A G + M FSI+ + V LD E + L I Sbjct: 225 QVMDLKPAESHFNASGG-TFAFFGSSGSM-FSINGTNLRVGST-PLDRETAEEHVLDISL 281 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 +GG ++ +N+ D+ND P F + F SV+E +G + V A D+D G N Sbjct: 282 TEGGIV--KGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGTVFLTVSATDSDAGAN 339 Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 + LTY++ GN + +I+ ++ + + QLDRET+ Y L V A DGG+P + T Sbjct: 340 SALTYSIA----AGNEEGFFSINNKTSAISVAKQLDRETRDLYMLTVMAQDGGEPSLNRT 395 Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407 A +V L+E TPV T+ A+D D + RL Y I G Sbjct: 396 AAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLLYSIESG- 454 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRY 437 G F I + G I+VA L + Q Y Sbjct: 455 AHGHFQI-KDSSSGAISVADRLSYNQRNNY 483 Score = 117 bits (282), Expect = 1e-25 Identities = 65/191 (34%), Positives = 101/191 (52%), Gaps = 3/191 (1%) Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRET ++L ++ +GG+ + V ++V+D+ND P F+ + ++ E +GT Sbjct: 267 LDRETAEEHVLDISLTEGGI--VKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGT 324 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V ATD+D G N + Y + EEG F I+ + I K LDRE+ + L + Sbjct: 325 VFLTVSATDSDAGANSALTYSI-AAGNEEGFFSINNKTSAISVAKQLDRETRDLYMLTVM 383 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A DGG P + T V I++ D ND+PPV + + +SE + I T + + A D D G Sbjct: 384 AQDGGEPSLNRTAAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGA 443 Query: 719 NAVVHYSIKGG 729 N + YSI+ G Sbjct: 444 NGRLLYSIESG 454 Score = 104 bits (250), Expect = 9e-22 Identities = 62/155 (40%), Positives = 83/155 (53%), Gaps = 3/155 (1%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F IN +TGAI+ K LDRET Y LTV A+DGG P L+ TT V I V D NDN PV + Sbjct: 3 FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 62 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTN 642 + ++ E A + T V+ V A+D D+G NGR+ Y ++ G F I D +SG I Sbjct: 63 AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLA 120 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 L + + DGG+P S +V I + Sbjct: 121 GMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 155 Score = 94.3 bits (224), Expect = 1e-18 Identities = 57/159 (35%), Positives = 86/159 (54%), Gaps = 7/159 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ ++GA+ LDRE +YT+ V A D P L+ST + + + D NDN P Sbjct: 3 FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---LNSTTAVAIQVGDANDNPPV 59 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGD 208 + VS+ E ++ D PV A + A+D D+GAN + Y+I G F I DS SG Sbjct: 60 IQDAVIRVSLSETAAI-DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGA 116 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 +SL L Y Q +Y +V+ DGGSP+ + ++I++ Sbjct: 117 ISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 155 Score = 88.6 bits (210), Expect = 6e-17 Identities = 51/151 (33%), Positives = 77/151 (50%), Gaps = 4/151 (2%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 FSI++ +G +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P Sbjct: 3 FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 62 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 ++ + S+SE I + V A D D G N L Y++ + G+ + D SG + Sbjct: 63 AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFQIK---DSSSGAIS 118 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 +G L + Y ++V TDGG P + A Sbjct: 119 LAGMLSYNQRNNYIVVVNVTDGGSPALKSRA 149 Score = 83.4 bits (197), Expect = 2e-15 Identities = 58/162 (35%), Positives = 83/162 (51%), Gaps = 11/162 (6%) Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVF 469 FSI N G I+VA+ LD + +Y LTV A D G + T V I + DAN+ PV Sbjct: 3 FSIN--NKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVI 60 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 ++A S+ E A I T V V A+D D+G N ++ YS+ E+ AH Q + + Sbjct: 61 QDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSS 113 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 +GAI+ +L + Y++ V DGG P+L V I V Sbjct: 114 SGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 155 Score = 82.6 bits (195), Expect = 4e-15 Identities = 64/219 (29%), Positives = 102/219 (46%), Gaps = 12/219 (5%) Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDRE+ H L +GG V V++ DIND P F+S ++E +GT Sbjct: 267 LDRETAEEHVLDISLTEGGIVKGLFKVTVNVL--DINDETPSFQSPSFNVSVNEIERLGT 324 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + A D D G N+ + YSI G++ FS+ + + + LD E+ R Y Sbjct: 325 VFLTVSATDSDAGANSALTYSIAAGNEEGFFSINNKTSA----ISVAKQLDRET-RDLYM 379 Query: 765 LVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821 L + A P L V I V D NDN PV++D I + + P V A D Sbjct: 380 LTVMAQDGGEPSLNRTAAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDK 439 Query: 822 DV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858 D+ +L Y I SG + + + + ++G+++++ +L+ N Sbjct: 440 DIGANGRLLYSIESGAHGHFQIKDSSSGAISVADRLSYN 478 Score = 82.2 bits (194), Expect = 5e-15 Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 15/193 (7%) Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 4 SINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDA 63 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 V L+E TPV T+ A+D D + RL Y I G G F I + G I++A Sbjct: 64 VIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQI-KDSSSGAISLAG 121 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE---DA 482 L + Q Y++ V+ TD G + AMV I++T P N Y SV E + Sbjct: 122 MLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PKPRNLTYDVSVLEGEANV 175 Query: 483 PIGTTVLVVSATD 495 + +VV+ TD Sbjct: 176 QVMDLKVVVNVTD 188 Score = 76.2 bits (179), Expect = 4e-13 Identities = 55/159 (34%), Positives = 79/159 (49%), Gaps = 8/159 (5%) Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F I+ +G I K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV + Sbjct: 3 FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 62 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 + +SE + I T + + A D D G N + YSI+ G + F ++ S L Sbjct: 63 AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAISLA 120 Query: 750 TMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVT 785 M L Y + R Y +V+ SP L + V I VT Sbjct: 121 GM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 156 Score = 52.4 bits (120), Expect = 5e-06 Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 6/124 (4%) Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 LD E+ R +Y L + A PPL + V I V D NDN PV++D I + + Sbjct: 18 LDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAID 76 Query: 811 GPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 P V A D D+ +L Y I SG + + + + ++G+++L+ L+ N + V+ Sbjct: 77 TPVATVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVN 136 Query: 869 VTDG 872 VTDG Sbjct: 137 VTDG 140 >SB_24627| Best HMM Match : Cadherin (HMM E-Value=0) Length = 262 Score = 145 bits (352), Expect = 4e-34 Identities = 87/224 (38%), Positives = 120/224 (53%), Gaps = 10/224 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V IN+ D N+ P+F++ + SV E +GT L VSATD D G N+ +TYS+ Sbjct: 22 VTINVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI------ 75 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 A + + F IN +TGAI+ K LDRET Y LTV A+DGG P L+ TT V I V D Sbjct: 76 -AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDA 134 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-D 633 NDN PV + + ++ E A + T V+ V A+D D+G NGR+ Y ++ G F I D Sbjct: 135 NDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKD 192 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 +SG I L + + DGG+P S +V I + Sbjct: 193 SSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 236 Score = 135 bits (327), Expect = 4e-31 Identities = 80/226 (35%), Positives = 119/226 (52%), Gaps = 7/226 (3%) Query: 126 VSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 +S+ LS A + +N++D ND P F ++ VSV+E + V + ATD D GAN Sbjct: 11 ISEDLSYIALQVTINVLDINDETPLFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGAN 68 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 SA+ Y+I GN + FSI++ +G +S+ K LD E Y L + AQDGG P ++TT + Sbjct: 69 SALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVA 128 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I + D NDN P ++ Q S+SE I + V A D D G N L Y++ + G+ Sbjct: 129 IQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSI-ESGAHGH 187 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 + D SG + +G L + Y ++V TDGG P + A Sbjct: 188 FQIK---DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRA 230 Score = 121 bits (292), Expect = 7e-27 Identities = 81/238 (34%), Positives = 119/238 (50%), Gaps = 26/238 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I Sbjct: 24 INVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 75 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 76 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 121 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST + + + D NDN P + VS+ E ++ D PV A + A+D D+GAN + Y+ Sbjct: 122 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAAI-DTPV-ATVIASDKDIGANGRLMYS 179 Query: 191 IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I G F I DS SG +SL L Y Q +Y +V+ DGGSP+ + ++I++ Sbjct: 180 IESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 236 Score = 116 bits (278), Expect = 4e-25 Identities = 77/222 (34%), Positives = 112/222 (50%), Gaps = 9/222 (4%) Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 V I+V+D+ND P+F+ + ++ E +GT V ATD D G N + Y + E Sbjct: 22 VTINVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNE 80 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 EG F I+ +G I K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV Sbjct: 81 EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPV 140 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 + + +SE + I T + + A D D G N + YSI+ G + F ++ S Sbjct: 141 IQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAI 198 Query: 747 ELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVT 785 L M L Y + R Y +V+ SP L + V I VT Sbjct: 199 SLAGM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 237 Score = 108 bits (259), Expect = 7e-23 Identities = 75/210 (35%), Positives = 107/210 (50%), Gaps = 13/210 (6%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F + V + E E GT +T++ATD D ++ L Y I GN G FSI N G I Sbjct: 36 FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSIN--NKTGAI 93 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481 +VA+ LD + +Y LTV A D G + T V I + DAN+ PV ++A S+ E Sbjct: 94 SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSET 153 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A I T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ +L Sbjct: 154 AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSY 206 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 + Y++ V DGG P+L V I V Sbjct: 207 NQRNNYIVVVNVTDGGSPALKSRAMVVIDV 236 Score = 92.3 bits (219), Expect = 5e-18 Identities = 64/205 (31%), Positives = 102/205 (49%), Gaps = 10/205 (4%) Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V I + DIND P+F+S ++E +GT + A D D G N+ + YSI G++ Sbjct: 22 VTINVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEE 81 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789 FS+ + G+ + LD E+ R +Y L + A PPL + V I V D ND Sbjct: 82 GFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAND 136 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTG 847 N PV++D I + + P V A D D+ +L Y I SG + + + + ++G Sbjct: 137 NPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSG 196 Query: 848 SMTLSPQLNTNVPKLATMEVSVTDG 872 +++L+ L+ N + V+VTDG Sbjct: 197 AISLAGMLSYNQRNNYIVVVNVTDG 221 Score = 41.1 bits (92), Expect = 0.012 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 6/99 (6%) Query: 778 VRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833 ++V I V D+ND P+ + F + N + V F V A D D L Y I + Sbjct: 20 LQVTINVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAA 77 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 GN +N TG+++++ QL+ T+ V DG Sbjct: 78 GNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 116 >SB_14427| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2325 Score = 144 bits (350), Expect = 7e-34 Identities = 193/736 (26%), Positives = 306/736 (41%), Gaps = 83/736 (11%) Query: 95 RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 R+GALL LD E A++TV ++A D +P T + V ++DDND P + Sbjct: 308 RNGALLATRPLDFESHAQWTVRIRAQDSGTPSK---YFTESFTVRVLDDND--PPTAITL 362 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAI--------RYAIIGGNTQMQFSIDSLS 206 + +VDE+ + + ++ + D D G R+ I G ++ S Sbjct: 363 SSSAVDENSGI--DTLVGYLSTRDEDSGQRFTYTLLDSARGRFKIEGDKLKVAQSNRECL 420 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 L+YE +++ + +R D G+ + L I IRD+ND PR L V Sbjct: 421 RQGGNSCLLNYEHNQTHLIRVRTTDSGTIPLTYDAVLTITIRDINDQ-PRDL-QLSNNRV 478 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 +EN IG S + D D G + L Y+++D D G +D G ++ + +D Sbjct: 479 AENASIGSSFGTFSSRDEDAGQS--LVYSLSDDD--GG---RFRVDA-VGKLFKAKDMDY 530 Query: 327 ETQAKYQLLVTATDGGDPP----RSATATXXXXXXXXXXXXXXFMPGQYEV-----ELAE 377 ETQ + + TD G P + T GQ ++ E Sbjct: 531 ETQRSHVIQAVVTDNGSPAMKMEKQFTIEVLDINEAPVHLNFTSTDGQLAFPPNSPKVRE 590 Query: 378 DEPPGTPVVTLTATDADEDNRL--HYEITGG-----NTRGRFSITSQNGRGLIT------ 424 + GT V TL A D D +L H + + G + + N RG T Sbjct: 591 NSELGTVVGTLEALDYDALQQLSFHLDDSAGEAFSLSASASLCVPVTNMRGFNTRCTHTL 650 Query: 425 -VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV---FENAPYTASVFE 480 V L+++Q + + + TD+ G T ++ ITD N+ AP TA+V E Sbjct: 651 RVNTTLNYEQNQAHYIVARVTDNKGLFTTRRFRVTITDEND-APAGITLAGNSLTATVDE 709 Query: 481 DAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 +A G V + D D +AQ TY L+ + + V ++ +V + + L Sbjct: 710 NAN-GALVGELVTIDED---SAQSHTYVLTDDAAGRFVTRANKLYV--------SRSANL 757 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E+ + Y +T+ + D G PSL+ + I V DVN E K L + + E++ T Sbjct: 758 DYESKNTYNITIRSTDTGNPSLNVSNTFSILVRDVN--EAPSKVSLSNSRVQENSPKDTV 815 Query: 600 VSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 + Q+ TD D N R ++ D G FV+D + + LD E + Sbjct: 816 IGQLTVTDPDNSAYNSRQSHKCSVVDDMIGQFVVDQGNVLKVGRVVLDFEQATVISVPVK 875 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 +D G PP S V+ +I ++D+N+SP + I+EN P T IG + DPD Sbjct: 876 CVDSGYPPLSLQVVFNITVDDVNESPADIALSGNS--IAENVP-ATYIGTLTTTDPDNEA 932 Query: 719 --NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPP 773 Y++ G F + D A L + L+YE + + IR + +PP Sbjct: 933 QFRQTFTYTLMGDTAGIPFVI------DGAALNSTRPLNYER-KAFWVFTIRSTDSGTPP 985 Query: 774 LWNDVRVEILVTDVND 789 L I V DVN+ Sbjct: 986 LSVTKTFNITVVDVNE 1001 Score = 130 bits (313), Expect = 2e-29 Identities = 159/613 (25%), Positives = 265/613 (43%), Gaps = 70/613 (11%) Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL---FQE 264 DV++ LD+E +S +++RA D S ++ + + DVND P +L Sbjct: 7 DVTVGVRLDFEVSQSELIIVRATD--SSGLFHSVAFNVTVIDVND--PPINVTLDGSLSG 62 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ- 323 +V+EN + I +Q ADE ++ +Y + D GN ++ R+ +YTS Sbjct: 63 TVNENSR-DFLIGSLQT--ADEDLHQTYSYILLS-DGGGNFEI------RADKLYTSSSA 112 Query: 324 -LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LD E YQL V +TD G PP S T + E+ PPG Sbjct: 113 NLDFEVARSYQLRVRSTDSGTPPLSVEGTVTITISDVNERPTNISLSASTI--TENTPPG 170 Query: 383 TPVVTLTATDADE-----DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 T + L+ D D D + H ++ GR +I G L+ + +++++ Sbjct: 171 TVIGRLSVIDPDNLGPQGDRQRHVCRLTDSSNGRVAI---QGNQLVVGSAGVNYERGSSL 227 Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 +TVS D GG A ++++D N + + + E+ P T V + TD D Sbjct: 228 NVTVSCADPGGLELLASFTVDVSDVNESPTAISIS--SLQILENRPALTKVGDLKVTDPD 285 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 + + T++L+ V F + + GA+ + LD E+ + + + + A+D G Sbjct: 286 NEVCQRQTFNLT-------VLSPLSPFKV--RNGALLATRPLDFESHAQWTVRIRAQDSG 336 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 PS T + V+D DN+P L ++ + E++ + T V + D D G R Sbjct: 337 TPSKYFTESFTVRVLD--DNDPPTAITLSSSAVDENSGIDTLVGYLSTRDEDSG--QRFT 392 Query: 618 YELDPKDREEGSFVID-PASGVIRTNK----------ALDRESVATHDLKAVAIDGGTPP 666 Y L D G F I+ V ++N+ L+ E TH ++ D GT P Sbjct: 393 YTL--LDSARGRFKIEGDKLKVAQSNRECLRQGGNSCLLNYEHNQTHLIRVRTTDSGTIP 450 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + ++ I I DIND P + ++EN+ IG++ G + D D G + V YS+ Sbjct: 451 LTYDAVLTITIRDINDQPR--DLQLSNNRVAENASIGSSFGTFSSRDEDAGQSLV--YSL 506 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK--YELVIRAASPPLWNDVRVEILV 784 DD F ++ +L D+DYE+ R +V SP + + + I V Sbjct: 507 -SDDDGGRFRVDA-----VGKLFKAKDMDYETQRSHVIQAVVTDNGSPAMKMEKQFTIEV 560 Query: 785 TDVNDNAPVMKDF 797 D+N+ APV +F Sbjct: 561 LDINE-APVHLNF 572 Score = 128 bits (308), Expect = 8e-29 Identities = 185/721 (25%), Positives = 297/721 (41%), Gaps = 79/721 (10%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LD E ++V+ATD S L + +V +ID ND P + V++D +S Sbjct: 14 LDFEVSQSELIIVRATD-----SSGLFHSVAFNVTVIDVND--PPIN-----VTLDGSLS 61 Query: 165 VTDNP-----VIAKIKATDADVGAN-SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 T N +I ++ D D+ S I + GGN +++ D L S LD+E Sbjct: 62 GTVNENSRDFLIGSLQTADEDLHQTYSYILLSDGGGNFEIR--ADKLYTSSSA--NLDFE 117 Query: 219 QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278 RSY+L +R+ D G+P S + I I DVN+ SL +++EN P G I R Sbjct: 118 VARSYQLRVRSTDSGTPPLSVEGTVTITISDVNERPTNI--SLSASTITENTPPGTVIGR 175 Query: 279 VQAYDAD----EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 + D D +G +TD G V + + V S ++ E + + Sbjct: 176 LSVIDPDNLGPQGDRQRHVCRLTDSS-NGRVAIQ-----GNQLVVGSAGVNYERGSSLNV 229 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 V+ D G A+ T +++ E+ P T V L TD D Sbjct: 230 TVSCADPGGLELLASFTVDVSDVNESPTAISIS----SLQILENRPALTKVGDLKVTDPD 285 Query: 395 ED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD- 451 + R + +T + F + +NG L T +PLDF+ ++ + + A DSG S Sbjct: 286 NEVCQRQTFNLTVLSPLSPFKV--RNGALLAT--RPLDFESHAQWTVRIRAQDSGTPSKY 341 Query: 452 -TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 T + + D N+ P +++V E++ I T V +S D D G + TY+L Sbjct: 342 FTESFTVRVLDDND--PPTAITLSSSAVDENSGIDTLVGYLSTRDEDSG--QRFTYTLLD 397 Query: 511 EISNEAVAHHDQQFVINPQTGAIT---TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 D+ V + + LL+ E +L+ V D G L+ + Sbjct: 398 SARGRFKIEGDKLKVAQSNRECLRQGGNSCLLNYEHNQTHLIRVRTTDSGTIPLTYDAVL 457 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 I++ D+ND QL + E+A +G+S + D D G + + Y L D + Sbjct: 458 TITIRDINDQPRDL--QLSNNRVAENASIGSSFGTFSSRDEDAGQS--LVYSLS--DDDG 511 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-- 685 G F +D A G + K +D E+ +H ++AV D G+P I++ DIN++P Sbjct: 512 GRFRVD-AVGKLFKAKDMDYETQRSHVIQAVVTDNGSPAMKMEKQFTIEVLDINEAPVHL 570 Query: 686 --VFESDCLTF-----YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD---SNSF 735 L F + ENS +GT +G + A D D H G+ S S Sbjct: 571 NFTSTDGQLAFPPNSPKVRENSELGTVVGTLEALDYDALQQLSFHLDDSAGEAFSLSASA 630 Query: 736 SL----ETRQGSDKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 SL +G + T+ L+YE + Y + + L+ R + +TD N Sbjct: 631 SLCVPVTNMRGFNTRCTHTLRVNTTLNYEQNQAHYIVARVTDNKGLFTTRRFRVTITDEN 690 Query: 789 D 789 D Sbjct: 691 D 691 Score = 119 bits (287), Expect = 3e-26 Identities = 168/706 (23%), Positives = 292/706 (41%), Gaps = 62/706 (8%) Query: 32 VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91 VRE + GT V TL+A D D + ++ + ++ D+ + V ++ Sbjct: 588 VRENSELGTVVGTLEALDYDALQ--QLSFHLD----DSAGEAFSLSASASLCVPVTNMRG 641 Query: 92 IDGR-SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP-- 148 + R + L +L+ E+ + ++ + TD L +T V I D+ND Sbjct: 642 FNTRCTHTLRVNTTLNYEQNQAHYIVARVTDNKG-----LFTTRRFRVTITDENDAPAGI 696 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 + + T +VDE+ + ++ ++ D D + ++ + +F + Sbjct: 697 TLAGNSLTATVDEN---ANGALVGELVTIDEDSAQSHTY---VLTDDAAGRFVTRANKLY 750 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 VS LDYE +Y + IR+ D G+PS + + I +RDVN+ AP SL V E Sbjct: 751 VSRSANLDYESKNTYNITIRSTDTGNPSLNVSNTFSILVRDVNE-APS-KVSLSNSRVQE 808 Query: 269 NVPIGYSIVRVQAYDADEGV-NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LD 325 N P I ++ D D N+ ++ + D ++ +D G V G+ LD Sbjct: 809 NSPKDTVIGQLTVTDPDNSAYNSRQSHKCSVVD---DMIGQFVVD--QGNVLKVGRVVLD 863 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTP 384 E + V D G PP S + G +AE+ P T Sbjct: 864 FEQATVISVPVKCVDSGYPPLSLQVVFNITVDDVNESPADIALSGN---SIAEN-VPATY 919 Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 + TLT TD D + + T I + +PL+++++ +V T+ +T Sbjct: 920 IGTLTTTDPDNEAQFRQTFTYTLMGDTAGIPFVIDGAALNSTRPLNYERKAFWVFTIRST 979 Query: 445 DSGGRSDTAMVQINITDAN-NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 DSG + NIT + N AP + ++ V E++ T + +S D D + Sbjct: 980 DSGTPPLSVTKTFNITVVDVNEAP-YGITVSSSDVDENSGQDTVIGTLSCQDPD--FDQS 1036 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK---LLDRETMSGYLLTVTARDGGVPS 560 +Y+L + +D V + I L+ E +++ V + D G P+ Sbjct: 1037 HSYTLIDDAGGRFKVENDTLMVALSNSDCIRLGGSACKLNYEGQRQHVIRVRSTDNGAPA 1096 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 + + I+V DVND + + + E+A +GT + ++ A+D D + + L Sbjct: 1097 RTSEKSLVITVNDVNDRPRDLRMSGF--KVEENAPIGTRIGKLTASDED--KYQTLSFSL 1152 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 D ++G F ID +SG + KA D E+ H + A A D GT + I + +I Sbjct: 1153 --VDDDKGRFAID-SSGYVMKVKATDYETSQLHTIIAQARDNGTKTLAVNQTFTIVVVNI 1209 Query: 681 NDSP-----------PVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 N++P F + T +SENSP GT +G + + D D Sbjct: 1210 NEAPINISITSLNGQQAFPDNAPT--VSENSPNGTVVGTLFSLDHD 1253 Score = 113 bits (271), Expect = 3e-24 Identities = 124/508 (24%), Positives = 206/508 (40%), Gaps = 38/508 (7%) Query: 200 FSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 F+I+S SG +SL LDYEQ +Y L +R+ D G P S Q +N+ DV DN R Sbjct: 1685 FAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDNGLPPLSTLGQFFVNVIDVLDNNDRPQ 1744 Query: 259 -TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 L +V EN G I +QA D D N ++++ D+ DL + R Sbjct: 1745 GIQLSPSTVLENATAGAVIGSLQARDQD--ANQTHSFSVVDR-----TDL---FEVRGSK 1794 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + ++ E + + A D G P S + + L E Sbjct: 1795 LVLVSSVNYEENPTINVTIRAADDGSPSLSKEEVLAVTVIDCNDAPSDVIIRPQNIVLPE 1854 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 + GTP+ +T D D + + G S++ G+ A LDF+ ++ Sbjct: 1855 NSKSGTPLANVTVVDDDTLQEHYCTLIDGQRYFYIKKLSRSEAGIFVAASELDFETMKQP 1914 Query: 438 V-LTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 + +TV TD G + N+T ++ N AP + V E+ G + +S D Sbjct: 1915 ITVTVKCTDDGNPQYSNQRSFNVTLSDINEAPYDITLTGSPVVEENVVKGYAIGSLSCKD 1974 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM---SGYLLTVT 552 DVG S + + V +D F +N + LD E + + +++ Sbjct: 1975 PDVG---------QSHVF-QVVGKYDNVFEVNGTNLIVKDPSYLDHEALPPPATLHISIR 2024 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A D G L T DV I+V DVN+ + + ED G ++QV +T+ +V Sbjct: 2025 ATDNGDTPLDVTNDVTINVTDVNEAPYDIRLVPSHVTVKEDIRTGQCIAQVTSTNPEVEQ 2084 Query: 613 N---GRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGG 663 + Y+ + + S + + + N L + + T+D+ A+D G Sbjct: 2085 TVSYSLLSYQTEFRINAVCLNSSLSSGNAAYLTVNGPLSYDKMESLNYTYDIMVEAMDNG 2144 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDC 691 PP + V +++E ++ P V E+ C Sbjct: 2145 IPPLAWNDSVFVRVERVD--PCVNETVC 2170 Score = 103 bits (246), Expect = 3e-21 Identities = 160/610 (26%), Positives = 253/610 (41%), Gaps = 60/610 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND +P ++ E + SGT + TL DQD+ ++ Y IE VTA Sbjct: 1616 ITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITADQDVRQSHS--YNIEHVTAYGF 1672 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSDR 129 + + +F I+ SG L L+ LD E+ A YT+ V++TD P Sbjct: 1673 GGKS-------NSSSLLGLFAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDNGLP---P 1722 Query: 130 LSSTATIHVNIID--DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 LS+ VN+ID DN++ PQ + + + ++ + T VI ++A D D AN Sbjct: 1723 LSTLGQFFVNVIDVLDNNDRPQGIQLSPSTVLE---NATAGAVIGSLQARDQD--ANQTH 1777 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++++ T + + + LV +++YE+ + + IRA D GSPS S L + + Sbjct: 1778 SFSVV-DRTDL---FEVRGSKLVLVSSVNYEENPTINVTIRAADDGSPSLSKEEVLAVTV 1833 Query: 248 RDVNDNAPRFYTSLFQESV-SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 D ND AP Q V EN G + V D D+ + + + Y Sbjct: 1834 IDCND-APSDVIIRPQNIVLPENSKSGTPLANVTVVD-DDTLQEHYCTLIDGQRYFYIKK 1891 Query: 307 LPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 L + +G + +LD ET + + V TD G+P S + Sbjct: 1892 LSRS---EAGIFVAASELDFETMKQPITVTVKCTDDGNPQYSNQRSFNVTLSDINEAPYD 1948 Query: 366 F-MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 + G VE E+ G + +L+ D D +++ G ++ NG LI Sbjct: 1949 ITLTGSPVVE--ENVVKGYAIGSLSCKDPDVGQSHVFQVVGKYD----NVFEVNGTNLI- 2001 Query: 425 VAQP--LDFK---QERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTAS 477 V P LD + +++ ATD+G T V IN+TD N P + Sbjct: 2002 VKDPSYLDHEALPPPATLHISIRATDNGDTPLDVTNDVTINVTDVNEAPYDIRLVPSHVT 2061 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSS---EISNEAVAHHDQQFVINPQTGAIT 534 V ED G + V++T+ +V ++YSL S E AV + + + +T Sbjct: 2062 VKEDIRTGQCIAQVTSTNPEV--EQTVSYSLLSYQTEFRINAVCLNSS--LSSGNAAYLT 2117 Query: 535 TNKLLDRETMSG----YLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTA 588 N L + M Y + V A D G+P L +D+ V + VD NE V A Sbjct: 2118 VNGPLSYDKMESLNYTYDIMVEAMDNGIPPLAWNDSVFVRVERVDPCVNETVCDGNATCA 2177 Query: 589 NIMEDALVGT 598 + +L T Sbjct: 2178 RVKGTSLTCT 2187 Score = 102 bits (245), Expect = 4e-21 Identities = 138/542 (25%), Positives = 229/542 (42%), Gaps = 48/542 (8%) Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273 TL+YEQ +++ +V R D + T + + I D ND AP T L S++ V Sbjct: 655 TLNYEQNQAHYIVARVTD--NKGLFTTRRFRVTITDEND-APAGIT-LAGNSLTATVDEN 710 Query: 274 YSIVRV-QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 + V + DE TY +TD D G +V S LD E++ Y Sbjct: 711 ANGALVGELVTIDEDSAQSHTYVLTD-DAAGR----FVTRANKLYVSRSANLDYESKNTY 765 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 + + +TD G+P + + T V+ E+ P T + LT TD Sbjct: 766 NITIRSTDTGNPSLNVSNTFSILVRDVNEAPSKVSLSNSRVQ--ENSPKDTVIGQLTVTD 823 Query: 393 ADED----NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448 D + H + G+F + N + V LDF+Q + V DSG Sbjct: 824 PDNSAYNSRQSHKCSVVDDMIGQFVVDQGNVLKVGRVV--LDFEQATVISVPVKCVDSGY 881 Query: 449 RSDTAMVQINIT-DANNYAPVFENAPYTASVFEDAP---IGTTVLVVSATDSDVGINAQI 504 + V NIT D N +P + A S+ E+ P IGT L + D++ Sbjct: 882 PPLSLQVVFNITVDDVNESPA-DIALSGNSIAENVPATYIGT--LTTTDPDNEAQFRQTF 938 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 TY+L + + FVI+ A+ + + L+ E + ++ T+ + D G P LS T Sbjct: 939 TYTLMGDTAGIP-------FVIDG--AALNSTRPLNYERKAFWVFTIRSTDSGTPPLSVT 989 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 I+VVDVN E + + ++++ E++ T + + D D + D Sbjct: 990 KTFNITVVDVN--EAPYGITVSSSDVDENSGQDTVIGTLSCQDPDFDQSHSYTLIDDAGG 1047 Query: 625 R---EEGSFVIDPA-SGVIRTNKA---LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 R E + ++ + S IR + L+ E H ++ + D G P ++S + I + Sbjct: 1048 RFKVENDTLMVALSNSDCIRLGGSACKLNYEGQRQHVIRVRSTDNGAPARTSEKSLVITV 1107 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 D+ND P F + EN+PIGT IG++ A D D+ + +S+ DD F++ Sbjct: 1108 NDVNDRPRDLRMS--GFKVEENAPIGTRIGKLTASDEDK--YQTLSFSLV-DDDKGRFAI 1162 Query: 738 ET 739 ++ Sbjct: 1163 DS 1164 Score = 90.6 bits (215), Expect = 2e-17 Identities = 171/731 (23%), Positives = 292/731 (39%), Gaps = 92/731 (12%) Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 A+LD E Y + V++TD +P LS T+ + I D N+ S T++ Sbjct: 112 ANLDFEVARSYQLRVRSTDSGTP---PLSVEGTVTITISDVNERPTNISLSASTITE--- 165 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQV 220 + VI ++ D D R + T ++ G+ +V + ++YE+ Sbjct: 166 -NTPPGTVIGRLSVIDPDNLGPQGDRQRHVCRLTDSSNGRVAIQGNQLVVGSAGVNYERG 224 Query: 221 RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 S + + D G +++ DVN++ S Q + EN P + ++ Sbjct: 225 SSLNVTVSCADPG--GLELLASFTVDVSDVNESPTAISISSLQ--ILENRPALTKVGDLK 280 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPIT-IDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 D D V T+ +T V P++ R+G + + LD E+ A++ + + A Sbjct: 281 VTDPDNEVCQRQTFNLT-------VLSPLSPFKVRNGALLATRPLDFESHAQWTVRIRAQ 333 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399 D G P + T + V+ E+ T V L+ D D R Sbjct: 334 DSGTPSKYFTESFTVRVLDDNDPPTAITLSSSAVD--ENSGIDTLVGYLSTRDEDSGQRF 391 Query: 400 HYEITGGNTRGRFSI------TSQNGRGLITVAQP---LDFKQERRYVLTVSATDSGGRS 450 Y + + RGRF I +Q+ R + L+++ + +++ V TDSG Sbjct: 392 TYTLL-DSARGRFKIEGDKLKVAQSNRECLRQGGNSCLLNYEHNQTHLIRVRTTDSGTIP 450 Query: 451 DT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 T A++ I I D N+ + + V E+A IG++ S+ D D G + YSL Sbjct: 451 LTYDAVLTITIRDINDQPRDLQLS--NNRVAENASIGSSFGTFSSRDEDAG--QSLVYSL 506 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 S + +F ++ G + K +D ET +++ D G P++ Sbjct: 507 SDDDGG--------RFRVD-AVGKLFKAKDMDYETQRSHVIQAVVTDNGSPAMKMEKQFT 557 Query: 569 ISVVDVNDNEPVF-------KQQLYTAN---IMEDALVGTSVSQVGATDADVGLNGRIHY 618 I V+D+N+ PV Q + N + E++ +GT V + A D D ++ + Sbjct: 558 IEVLDINE-APVHLNFTSTDGQLAFPPNSPKVRENSELGTVVGTLEALDYDA--LQQLSF 614 Query: 619 ELDPKDREEGSF-----VIDPASGV----------IRTNKALDRESVATHDLKAVAIDGG 663 LD E S + P + + +R N L+ E H + A D Sbjct: 615 HLDDSAGEAFSLSASASLCVPVTNMRGFNTRCTHTLRVNTTLNYEQNQAHYIVARVTD-- 672 Query: 664 TPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 +T + I D ND+P + LT + EN+ G +GE+ D D +A Sbjct: 673 NKGLFTTRRFRVTITDENDAPAGITLAGNSLTATVDENAN-GALVGELVTIDED---SAQ 728 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778 H + D + F TR ++K + +LDYES + Y + IR+ +P L Sbjct: 729 SHTYVLTDDAAGRF--VTR--ANKLYVSRSANLDYES-KNTYNITIRSTDTGNPSLNVSN 783 Query: 779 RVEILVTDVND 789 ILV DVN+ Sbjct: 784 TFSILVRDVNE 794 Score = 88.2 bits (209), Expect = 8e-17 Identities = 113/501 (22%), Positives = 213/501 (42%), Gaps = 44/501 (8%) Query: 386 VTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 VT+T+TD + H +EI R ++TS + +G T + + + R +TV++ Sbjct: 1550 VTVTSTDNKGNTASHNGHEIH----RSSVTVTSTDNKGN-TASH--NGHEIYRSSVTVTS 1602 Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV----- 498 TD+ G + T I + D N+ AP +A ++ E +P GT + + D DV Sbjct: 1603 TDNKGLNVTNSFVITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITADQDVRQSHS 1661 Query: 499 -GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLLDRETMSGYLLTVTARDG 556 I Y + ++ ++ F I +G ++ + LLD E + Y LTV + D Sbjct: 1662 YNIEHVTAYGFGGKSNSSSLLG---LFAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDN 1718 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G+P LS ++V+DV DN + QL + ++E+A G + + A D D Sbjct: 1719 GLPPLSTLGQFFVNVIDVLDNNDRPQGIQLSPSTVLENATAGAVIGSLQARDQDANQT-- 1776 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + DR + + + + +++ E T ++ A D G+P S ++ + Sbjct: 1777 --HSFSVVDRTD---LFEVRGSKLVLVSSVNYEENPTINVTIRAADDGSPSLSKEEVLAV 1831 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 + D ND+P + ENS GT + + D D HY D F Sbjct: 1832 TVIDCNDAPSDVIIRPQNIVLPENSKSGTPLANVTVVDDD---TLQEHYCTL-IDGQRYF 1887 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 ++ S+ V +LD+E+ ++ + ++ +P N + ++D+N+ AP Sbjct: 1888 YIKKLSRSEAGIFVAASELDFETMKQPITVTVKCTDDGNPQYSNQRSFNVTLSDINE-AP 1946 Query: 793 ---VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849 + ++ N + + G + D DV ++++ G N+ +N T + Sbjct: 1947 YDITLTGSPVVEENVVKGYAI---GSLSCKDPDVGQSHVFQVV-GKYDNVFEVNGTNLIV 2002 Query: 850 TLSPQLNTN-VPKLATMEVSV 869 L+ +P AT+ +S+ Sbjct: 2003 KDPSYLDHEALPPPATLHISI 2023 Score = 80.6 bits (190), Expect = 2e-14 Identities = 132/596 (22%), Positives = 236/596 (39%), Gaps = 51/596 (8%) Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 YR + + + T +I ++D ND AP ++ +++E+ P G I + Sbjct: 1594 YRSSVTVTSTDNKGLNVTNSFVITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITA 1652 Query: 283 DAD----EGVNAE--LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL-DRETQAKYQLL 335 D D N E Y K + ++ I+ SG + SG L D E A Y L Sbjct: 1653 DQDVRQSHSYNIEHVTAYGFGGKSNSSSLLGLFAIESPSGKLSLSGPLLDYEQYANYTLT 1712 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDAD 394 V +TD G PP S Q + E+ G + +L A D D Sbjct: 1713 VRSTDNGLPPLSTLGQFFVNVIDVLDNNDRPQGIQLSPSTVLENATAGAVIGSLQARDQD 1772 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DT 452 + + + R + G L+ V+ +++++ +T+ A D G S Sbjct: 1773 ANQTHSFSVVD-----RTDLFEVRGSKLVLVSS-VNYEENPTINVTIRAADDGSPSLSKE 1826 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 ++ + + D N+ P + E++ GT + V+ D D + + I Sbjct: 1827 EVLAVTVIDCNDAPSDVIIRPQNIVLPENSKSGTPLANVTVVDDDT-----LQEHYCTLI 1881 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISV 571 + + + + + G LD ETM + +TV D G P S+ +++ Sbjct: 1882 DGQRYFYIKK--LSRSEAGIFVAASELDFETMKQPITVTVKCTDDGNPQYSNQRSFNVTL 1939 Query: 572 VDVNDNEPVFKQQLYTANIMEDALV-GTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 D+N E + L + ++E+ +V G ++ + D DVG + + + + F Sbjct: 1940 SDIN--EAPYDITLTGSPVVEENVVKGYAIGSLSCKDPDVGQS----HVFQVVGKYDNVF 1993 Query: 631 VIDPASGVIRTNKALDRESV---ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 ++ + +++ LD E++ AT + A D G P T V I + D+N++P Sbjct: 1994 EVNGTNLIVKDPSYLDHEALPPPATLHISIRATDNGDTPLDVTNDVTINVTDVNEAPYDI 2053 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSD 744 + E+ G I ++ + +P+ V YS+ N+ L + S Sbjct: 2054 RLVPSHVTVKEDIRTGQCIAQVTSTNPE--VEQTVSYSLLSYQTEFRINAVCLNSSLSSG 2111 Query: 745 KAELVTM-VDLDY---ESPRKKYELVIRAAS---PPL-WND---VRVEILVTDVND 789 A +T+ L Y ES Y++++ A PPL WND VRVE + VN+ Sbjct: 2112 NAAYLTVNGPLSYDKMESLNYTYDIMVEAMDNGIPPLAWNDSVFVRVERVDPCVNE 2167 Score = 79.8 bits (188), Expect = 3e-14 Identities = 105/404 (25%), Positives = 173/404 (42%), Gaps = 50/404 (12%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F IDG AL + L+ E+ A + +++TD +P LS T T ++ ++D N+ Sbjct: 951 FVIDG--AALNSTRPLNYERKAFWVFTIRSTDSGTPP---LSVTKTFNITVVDVNE--AP 1003 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII---GGNTQMQFS--IDS 204 + + VDE+ + VI + D D + + Y +I GG +++ + + Sbjct: 1004 YGITVSSSDVDENSG--QDTVIGTLSCQDPDFDQSHS--YTLIDDAGGRFKVENDTLMVA 1059 Query: 205 LSGDVSL-----VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 LS + L+YE R + + +R+ D G+P+R++ L+I + DVND Sbjct: 1060 LSNSDCIRLGGSACKLNYEGQRQHVIRVRSTDNGAPARTSEKSLVITVNDVNDRPRDLRM 1119 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 S F+ V EN PIG I ++ A D D+ L++++ D D G ID SG+V Sbjct: 1120 SGFK--VEENAPIGTRIGKLTASDEDK--YQTLSFSLVDDD-KGR----FAIDS-SGYVM 1169 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX----XXXFMPGQYEVE- 374 D ET + ++ A D G + T + GQ Sbjct: 1170 KVKATDYETSQLHTIIAQARDNGTKTLAVNQTFTIVVVNINEAPINISITSLNGQQAFPD 1229 Query: 375 ----LAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-----TRGRFSITSQNGRGLI-- 423 ++E+ P GT V TL + D D +L ++IT T + T+ G G I Sbjct: 1230 NAPTVSENSPNGTVVGTLFSLDHDAVQKLSFQITNNKFTLDPTPVCHNQTNIPGVGTICS 1289 Query: 424 ---TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464 V LD++Q R + V D G S + + + DAN+ Sbjct: 1290 TKLRVRGGLDYEQSAREDVIVRVMDDHGLSLSQRFTVQVLDAND 1333 Score = 52.0 bits (119), Expect = 7e-06 Identities = 88/372 (23%), Positives = 147/372 (39%), Gaps = 40/372 (10%) Query: 443 ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT-------VLVVSATD 495 AT + + + + D +N P +N ++ +V + + G+ + V + D Sbjct: 1482 ATVAENSGPVVVGRFHTIDPDNEGPWAQNQTFSYTVIKQSGTGSPFSTEGDFLKTVRSLD 1541 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTA 553 + + +T + + N A +H+ + + T T NK Y +VT Sbjct: 1542 YETRNSWSVTVTSTDNKGNTA-SHNGHEIHRSSVTVTSTDNKGNTASHNGHEIYRSSVTV 1600 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 L+ T I+V D ND P NI E + GT + + D DV + Sbjct: 1601 TSTDNKGLNVTNSFVITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITADQDVRQS 1659 Query: 614 GRIH------YELDPKDREE---GSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGG 663 + Y K G F I+ SG + + LD E A + L + D G Sbjct: 1660 HSYNIEHVTAYGFGGKSNSSSLLGLFAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDNG 1719 Query: 664 TPPQSSTVIVHIKIEDI---NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 PP S+ + + D+ ND P + T + EN+ G IG ++A D D N Sbjct: 1720 LPPLSTLGQFFVNVIDVLDNNDRPQGIQLSPST--VLENATAGAVIGSLQARDQD--ANQ 1775 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777 +S+ D ++ F + +GS +LV + ++YE + IRAA SP L + Sbjct: 1776 THSFSVV--DRTDLFEV---RGS---KLVLVSSVNYEE-NPTINVTIRAADDGSPSLSKE 1826 Query: 778 VRVEILVTDVND 789 + + V D ND Sbjct: 1827 EVLAVTVIDCND 1838 Score = 33.9 bits (74), Expect = 1.9 Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 16/138 (11%) Query: 210 SLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +LV T L++E + ++R D G+P + I ++DVN+ AP L +V+ Sbjct: 1428 TLVSTGDLNHEATPTIDAILRCYDDGTPRLYLEKTITIFVKDVNE-APS-GIHLAGATVA 1485 Query: 268 ENV-PIGYSIVRVQAYDAD-EG---VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 EN P+ + R D D EG N +YT+ + TG+ P + + ++ T Sbjct: 1486 ENSGPV--VVGRFHTIDPDNEGPWAQNQTFSYTVIKQSGTGS---PFSTE--GDFLKTVR 1538 Query: 323 QLDRETQAKYQLLVTATD 340 LD ET+ + + VT+TD Sbjct: 1539 SLDYETRNSWSVTVTSTD 1556 Score = 33.5 bits (73), Expect = 2.5 Identities = 38/120 (31%), Positives = 54/120 (45%), Gaps = 16/120 (13%) Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PIG 703 L+ E+ T D D GTP + I ++D+N++P T ++ENS P+ Sbjct: 1435 LNHEATPTIDAILRCYDDGTPRLYLEKTITIFVKDVNEAPSGIHLAGAT--VAENSGPV- 1491 Query: 704 TTIGEIRAHDPD-EGP---NAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 +G DPD EGP N Y+ IK + FS E G L T+ LDYE+ Sbjct: 1492 -VVGRFHTIDPDNEGPWAQNQTFSYTVIKQSGTGSPFSTE---GD---FLKTVRSLDYET 1544 Score = 32.7 bits (71), Expect = 4.4 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGA-ECSDLWDTYICDCKEGHTGKDC 1348 C + + C +PC A +C D + C C+EG+TG C Sbjct: 2260 CSREINECEPSPCGQYALDCKDGIARFECICQEGYTGTVC 2299 >SB_56813| Best HMM Match : Cadherin (HMM E-Value=5.8e-40) Length = 211 Score = 137 bits (331), Expect = 1e-31 Identities = 83/212 (39%), Positives = 119/212 (56%), Gaps = 13/212 (6%) Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 +DT +V+I ITD N+ P+FE Y SV E A G +L VSA D D G+NA+++Y +S Sbjct: 3 TDT-IVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYIS 61 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 N A F +N + G I LDRE + Y LT+TA+DG S V + Sbjct: 62 EGNINGA-------FEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNV 111 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 V+D+NDN P F++ Y N+ E+ GT V ++ A+D D+G +G+ Y++ + + Sbjct: 112 YVLDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGL--SA 169 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAID 661 F I+P +G IRT LDRE A +D A AID Sbjct: 170 FTINPLTGEIRTRIKLDRELKARYDFIAFAID 201 Score = 123 bits (296), Expect = 2e-27 Identities = 72/205 (35%), Positives = 108/205 (52%), Gaps = 10/205 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + + I D+NDN P F EK Y +SV E S + K+ A D D G N+ + Y I GN Sbjct: 7 VEIIITDENDNPPIFEEKVYNISVLE--SAASGMELLKVSAVDRDFGVNARVSYYISEGN 64 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 F ++ G + L TLD E V Y+L + A+DG S + + + D+NDN P Sbjct: 65 INGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNVYVLDINDNNP 121 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 +F S ++ +VSEN P G +V+++A D D G + + Y D +G TI+P + Sbjct: 122 KFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLY-----DISGQGLSAFTINPLT 176 Query: 316 GWVYTSGQLDRETQAKYQLLVTATD 340 G + T +LDRE +A+Y + A D Sbjct: 177 GEIRTRIKLDRELKARYDFIAFAID 201 Score = 116 bits (279), Expect = 3e-25 Identities = 72/212 (33%), Positives = 111/212 (52%), Gaps = 12/212 (5%) Query: 564 TTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 TTD VEI + D NDN P+F++++Y +++E A G + +V A D D G+N R+ Y + Sbjct: 2 TTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYIS 61 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 + G+F ++ G IR LDRE+V + L A DG S V++ + DIN Sbjct: 62 -EGNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNVYVLDIN 117 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D+ P FE +SEN P GT + ++RA DPD G + Y I G ++F++ Sbjct: 118 DNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDI-SGQGLSAFTINPLT 176 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPP 773 G E+ T + LD E + +Y+ + A P Sbjct: 177 G----EIRTRIKLDREL-KARYDFIAFAIDSP 203 Score = 92.7 bits (220), Expect = 4e-18 Identities = 66/222 (29%), Positives = 104/222 (46%), Gaps = 28/222 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ P+FE + Y SV E A+SG +L + A D+D G NA V Y I Sbjct: 8 EIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYIS------ 61 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ++ G + +LDRE V Y + + A D + Sbjct: 62 -------------EGNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKD------GK 102 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S AT++V ++D NDN P+F + Y V+V E+ ++ K++A+D D+G + Y Sbjct: 103 YSGEATVNVYVLDINDNNPKFEKSHYRVNVSENRPA--GTLVVKLRASDPDLGESGKFLY 160 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 I G F+I+ L+G++ LD E Y + A D Sbjct: 161 D-ISGQGLSAFTINPLTGEIRTRIKLDRELKARYDFIAFAID 201 Score = 92.3 bits (219), Expect = 5e-18 Identities = 68/215 (31%), Positives = 102/215 (47%), Gaps = 12/215 (5%) Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 ++ T + I I D NDN P F ++ SV E+ G +++V A D D GVNA ++Y + Sbjct: 1 KTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYI 60 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 ++ GN++ ++ G + +G LDRE Y+L +TA DG S AT Sbjct: 61 SE----GNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNVYV 113 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414 F Y V ++E+ P GT VV L A+D D E + Y+I+G +G + Sbjct: 114 LDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISG---QGLSAF 170 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 T G I LD + + RY A DS G+ Sbjct: 171 TINPLTGEIRTRIKLDRELKARYDFIAFAIDSPGK 205 Score = 86.2 bits (204), Expect = 3e-16 Identities = 59/179 (32%), Positives = 91/179 (50%), Gaps = 13/179 (7%) Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y + + E G ++ ++A D D + R+ Y I+ GN G F + + G I +A Sbjct: 26 YNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAFEVNREFGT--IRLAGT 83 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD + Y LT++A D G S A V + + D N+ P FE + Y +V E+ P GT V Sbjct: 84 LDRENVDHYKLTLTAKD-GKYSGEATVNVYVLDINDNNPKFEKSHYRVNVSENRPAGTLV 142 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 + + A+D D+G + + Y +IS + ++ F INP TG I T LDRE + Y Sbjct: 143 VKLRASDPDLGESGKFLY----DISGQGLS----AFTINPLTGEIRTRIKLDRELKARY 193 Score = 61.3 bits (142), Expect = 1e-08 Identities = 49/185 (26%), Positives = 84/185 (45%), Gaps = 8/185 (4%) Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +++ IV I I D ND+PP+FE + E++ G + ++ A D D G NA V Y I Sbjct: 1 KTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYI 60 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786 G+ + +F + G+ + LD E+ Y+L + A + V + V D Sbjct: 61 SEGNINGAFEVNREFGT----IRLAGTLDRENV-DHYKLTLTAKDGKYSGEATVNVYVLD 115 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRI-LSGNNANLILLNE 844 +NDN P + N + P G ++ A D D+ + ++ +SG + +N Sbjct: 116 INDNNPKFEKSHYRV-NVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLSAFTINP 174 Query: 845 TTGSM 849 TG + Sbjct: 175 LTGEI 179 >SB_30491| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1516 Score = 136 bits (330), Expect = 2e-31 Identities = 100/307 (32%), Positives = 149/307 (48%), Gaps = 12/307 (3%) Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y ++E+ ++ +TA DAD E+ RL+Y I GNT F++ + G + + + Sbjct: 452 YNKVISENTTVDATILRVTANDADSGENARLNYAIETGNTNDTFALDTSTGE--LRLHKS 509 Query: 429 LDFKQERRYVLTVSATDSGGRSDTA-----MVQINITDAN-NYAPVFENAPYTASVFEDA 482 L K Y LT++A D G + T+ +++ D+ P F Y A+V E Sbjct: 510 LRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDSGPTKRPTFPVPIYLATVNEST 569 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+ T +L V A + + I+Y LS + D F +N QTGAI NK LD E Sbjct: 570 PLYTEILRVRARN-ERKYEGSISYFLSHISGGDKEGDVDLHFGVNSQTGAIRLNKKLDYE 628 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y+ V A D S DT V I V DVNDN P F Q Y+ +++ + +V Sbjct: 629 KTKRYVFLVGAIDVRTASPVDTVLVRILVQDVNDNRPEFYQYRYSRVFLKEPPLYYAVDT 688 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A DAD G NGR+ Y + E F ID +GV++T++ L R+++ +L D Sbjct: 689 VMAKDADSGQNGRLSYWIS-GGNEGNFFAIDSRTGVVKTSRMLQRQTLRLFNLTISVADQ 747 Query: 663 GTPPQSS 669 G+PP S Sbjct: 748 GSPPMKS 754 Score = 130 bits (313), Expect = 2e-29 Identities = 96/344 (27%), Positives = 161/344 (46%), Gaps = 27/344 (7%) Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 ++I + D+NDN PRF ++ + +SEN + +I+RV A DAD G NA L Y + T Sbjct: 433 VIIRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIE----T 488 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 GN + +D +G + L + Y L +TA D G+P ++ Sbjct: 489 GNTNDTFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDS 548 Query: 363 XXXFMP----GQYEVELAEDEPPGTPVVTLTA-TDADEDNRLHY---EITGGNTRG---- 410 P Y + E P T ++ + A + + + Y I+GG+ G Sbjct: 549 GPTKRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLSHISGGDKEGDVDL 608 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPV 468 F + SQ G I + + LD+++ +RYV V A D + DT +V+I + D N+ P Sbjct: 609 HFGVNSQT--GAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRILVQDVNDNRPE 666 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F Y+ ++ P+ V V A D+D G N +++Y +S NE F I+ Sbjct: 667 FYQYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISG--GNEG-----NFFAIDS 719 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 +TG + T+++L R+T+ + LT++ D G P + D + V+ Sbjct: 720 RTGVVKTSRMLQRQTLRLFNLTISVADQGSPPMKSEKDALVQVL 763 Score = 125 bits (302), Expect = 4e-28 Identities = 98/340 (28%), Positives = 148/340 (43%), Gaps = 28/340 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F + Y + E + T+L + A D D G+NA + Y IE T +T Sbjct: 435 IRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIE--TGNT- 491 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D F +D +G L SL + Y + + A DQ P Sbjct: 492 ----------------NDTFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSD 535 Query: 131 SSTATIHVNIIDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 I V D P F Y +V+E + + + + G+ S Sbjct: 536 PVHVFIKVQRHDSGPTKRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLS 595 Query: 190 AIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I GG+ + + F ++S +G + L K LDYE+ + Y ++ A D + S +T + I Sbjct: 596 HISGGDKEGDVDLHFGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRI 655 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++DVNDN P FY + + P+ Y++ V A DAD G N L+Y ++ GN Sbjct: 656 LVQDVNDNRPEFYQYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISG----GNE 711 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 ID R+G V TS L R+T + L ++ D G PP Sbjct: 712 GNFFAIDSRTGVVKTSRMLQRQTLRLFNLTISVADQGSPP 751 Score = 120 bits (290), Expect = 1e-26 Identities = 87/300 (29%), Positives = 143/300 (47%), Gaps = 18/300 (6%) Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 A+V I + D N+ P F Y + E+ + T+L V+A D+D G NA++ Y++ + Sbjct: 431 ALVIIRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIETGN 490 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SDTTDVEISV 571 +N+ F ++ TG + +K L + Y LT+TA+D G P++ SD V I V Sbjct: 491 TNDT-------FALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKV 543 Query: 572 VDVNDN---EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL------DP 622 + P F +Y A + E + T + +V A + + G I Y L D Sbjct: 544 QRHDSGPTKRPTFPVPIYLATVNESTPLYTEILRVRARN-ERKYEGSISYFLSHISGGDK 602 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 + + F ++ +G IR NK LD E + AID T TV+V I ++D+ND Sbjct: 603 EGDVDLHFGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRILVQDVND 662 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + P F + + P+ + + A D D G N + Y I GG++ N F++++R G Sbjct: 663 NRPEFYQYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDSRTG 722 Score = 119 bits (286), Expect = 4e-26 Identities = 90/322 (27%), Positives = 155/322 (48%), Gaps = 12/322 (3%) Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 A + + + D NDN P+F Y + E+ +V + I ++ A DAD G N+ + YAI Sbjct: 431 ALVIIRVDDLNDNKPRFVLPVYNKVISENTTV--DATILRVTANDADSGENARLNYAIET 488 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVND 252 GNT F++D+ +G++ L K+L + Y L + A+D G P+ S+ + I ++ + Sbjct: 489 GNTNDTFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDS 548 Query: 253 ---NAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD--EGVNAELTYTMTDKDYTGNVDL 307 P F ++ +V+E+ P+ I+RV+A + EG + ++ D G+VDL Sbjct: 549 GPTKRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLSHISGGDKEGDVDL 608 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++ ++G + + +LD E +Y LV A D T F Sbjct: 609 HFGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRILVQDVNDNRPEFY 668 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 +Y ++ P V T+ A DAD ++ RL Y I+GGN F+I S+ G++ Sbjct: 669 QYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDSRT--GVVKT 726 Query: 426 AQPLDFKQERRYVLTVSATDSG 447 ++ L + R + LT+S D G Sbjct: 727 SRMLQRQTLRLFNLTISVADQG 748 Score = 119 bits (286), Expect = 4e-26 Identities = 101/352 (28%), Positives = 163/352 (46%), Gaps = 17/352 (4%) Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 V I V D+NDN+P F +Y I E+ V ++ +V A DAD G N R++Y ++ + Sbjct: 433 VIIRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIETGNTN 492 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSP- 684 + +F +D ++G +R +K+L + ++L A D G P +S + V IK++ + P Sbjct: 493 D-TFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDSGPT 551 Query: 685 --PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY--SIKGGDDSNSFSLETR 740 P F ++E++P+ T I +RA + + ++ ++ I GGD L Sbjct: 552 KRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLSHISGGDKEGDVDLHFG 611 Query: 741 QGSDKAELVTMVDLDYESPRKKYELV----IRAASPPLWNDVRVEILVTDVNDNAPVMKD 796 S + LDYE ++ LV +R ASP + V V ILV DVNDN P Sbjct: 612 VNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPV--DTVLVRILVQDVNDNRPEFYQ 669 Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 ++ K+ V A DAD +L Y I GN N ++ TG + S Sbjct: 670 YRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDSRTGVVKTSRM 729 Query: 855 LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVR-LITEEMLLNSITVRLNDMT 904 L +L + +SV D G +K+ V+ LI + L+ V ++ T Sbjct: 730 LQRQTLRLFNLTISVADQGSPPMKSEKDALVQVLIFHPISLHMTLVETSETT 781 Score = 112 bits (269), Expect = 4e-24 Identities = 105/371 (28%), Positives = 168/371 (45%), Gaps = 37/371 (9%) Query: 403 ITGGNTRGRFSITS--QNGRGLITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINI 459 +T GN F + + +N + + + LD + Y LT+ A + + A ++I + Sbjct: 25 VTSGNEESIFKLINYPRNNSASLILQRELDREVASGYNLTIKALNIHENKFRLAHIRIVV 84 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 D N+ AP F + Y ++F + G + V+A D D G NA I Y L + Sbjct: 85 IDENDNAPTFPPSGYHTTIFTNVTEGQEIFRVNAIDVDTGDNANIRYHL---------LN 135 Query: 520 HDQQFVINPQTGAIT-TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 H Q F I P+TG + T + + + + V A +G ++ T I+V VN+ Sbjct: 136 HQQLFSIMPKTGVLVKTKERFAIDRTRNFTVIVVAINGEFKNVGTVT---ITVHPVNERR 192 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P F ++ Y + E VGTSV++V A D D G G++ Y + + F ID GV Sbjct: 193 PTFLKRNYEVKVSEAVQVGTSVAKVFAADPDYGNLGKLRYSILTESCP--FFGIDD-DGV 249 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTP----PQSSTVIVHIK-IEDINDSPPVFESDCLT 693 IR + L R L+ A D G P P+ +TV + I+ +E++ PV+E Sbjct: 250 IRNVQPLTRHGGENCTLEITAQDSGIPPLETPRPATVSIVIEPVENLKFDVPVYE----- 304 Query: 694 FYISENSPIGTTIGEIRA---HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 I EN +G+ I +RA P +V YSI+ D + SF + G + T Sbjct: 305 ISIPENIILGSEILTVRAVAGSGNRRNPRKIV-YSIENIDGALSFKI----GKHTGRITT 359 Query: 751 MVDLDYESPRK 761 +DYE ++ Sbjct: 360 RTHIDYEKTKE 370 Score = 101 bits (243), Expect = 6e-21 Identities = 90/347 (25%), Positives = 149/347 (42%), Gaps = 24/347 (6%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 S +L+ + LDRE + Y + +KA + + + A I + +ID+NDN P F Y Sbjct: 44 SASLILQRELDREVASGYNLTIKALN----IHENKFRLAHIRIVVIDENDNAPTFPPSGY 99 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215 ++ + VT+ I ++ A D D G N+ IRY ++ N Q FSI +G LVKT Sbjct: 100 HTTIFTN--VTEGQEIFRVNAIDVDTGDNANIRYHLL--NHQQLFSIMPKTG--VLVKTK 153 Query: 216 D---YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 + ++ R++ +++ A +G N + I + VN+ P F ++ VSE V + Sbjct: 154 ERFAIDRTRNFTVIVVAING---EFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQV 210 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G S+ +V A D D G +L Y++ + P G + L R Sbjct: 211 GTSVAKVFAADPDYGNLGKLRYSILTE------SCPFFGIDDDGVIRNVQPLTRHGGENC 264 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 L +TA D G PP F YE+ + E+ G+ ++T+ A Sbjct: 265 TLEITAQDSGIPPLETPRPATVSIVIEPVENLKFDVPVYEISIPENIILGSEILTVRAVA 324 Query: 393 ADEDNRLHYEITGG--NTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 + R +I N G S G IT +D+++ + Y Sbjct: 325 GSGNRRNPRKIVYSIENIDGALSFKIGKHTGRITTRTHIDYEKTKEY 371 Score = 77.4 bits (182), Expect = 2e-13 Identities = 79/328 (24%), Positives = 138/328 (42%), Gaps = 38/328 (11%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H +I V+D ND++P F Y ++ + G + + A D D G NA + Y + Sbjct: 79 HIRIVVIDENDNAPTFPPSGYHTTIFTNVTEGQEIFRVNAIDVDTGDNANIRYHL----- 133 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALL-TRASLDREKVARYTVLVKATDQASPV 126 LN Q +F I ++G L+ T+ ++ +TV+V A + Sbjct: 134 --LNH--------------QQLFSIMPKTGVLVKTKERFAIDRTRNFTVIVVA------I 171 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + + T+ + + N+ P F ++ Y V V E + V + +AK+ A D D G Sbjct: 172 NGEFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQVGTS--VAKVFAADPDYGNLGK 229 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +RY+I+ + F ID G + V+ L + L I AQD G P ++ Sbjct: 230 LRYSILTESCPF-FGIDD-DGVIRNVQPLTRHGGENCTLEITAQDSGIPPLETPRPATVS 287 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDADEGVNAELTYTMTDKDYTGN 304 I +F +++ S+ EN+ +G I VR A + ++ Y++ + D Sbjct: 288 IVIEPVENLKFDVPVYEISIPENIILGSEILTVRAVAGSGNRRNPRKIVYSIENIDGA-- 345 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKY 332 L I +G + T +D E +Y Sbjct: 346 --LSFKIGKHTGRITTRTHIDYEKTKEY 371 Score = 76.6 bits (180), Expect = 3e-13 Identities = 52/163 (31%), Positives = 79/163 (48%), Gaps = 15/163 (9%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVSDRLSSTATIHVNIIDDNDNY 147 F ++ ++GA+ LD EK RY LV A D ASPV T + + + D NDN Sbjct: 610 FGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVD-----TVLVRILVQDVNDNR 664 Query: 148 PQFSEKTYTVSVDEDISVTDNPV---IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 P+F + Y+ + + + P+ + + A DAD G N + Y I GGN F+IDS Sbjct: 665 PEFYQYRYS-----RVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDS 719 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 +G V + L + +R + L I D GSP + L+ + Sbjct: 720 RTGVVKTSRMLQRQTLRLFNLTISVADQGSPPMKSEKDALVQV 762 Score = 74.1 bits (174), Expect = 1e-12 Identities = 95/349 (27%), Positives = 136/349 (38%), Gaps = 28/349 (8%) Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 S + L + LD E Y L I+A + ++ + I + D NDNAP F S + + Sbjct: 44 SASLILQRELDREVASGYNLTIKALNIHE-NKFRLAHIRIVVIDENDNAPTFPPSGYHTT 102 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG-WVYTSGQL 324 + NV G I RV A D D G NA + Y + N +I P++G V T + Sbjct: 103 IFTNVTEGQEIFRVNAIDVDTGDNANIRYHLL------NHQQLFSIMPKTGVLVKTKERF 156 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 + + ++V A +G T F+ YEV+++E GT Sbjct: 157 AIDRTRNFTVIVVAING---EFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQVGTS 213 Query: 385 VVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V + A D D N +L Y I + F I G+I QPL L ++ Sbjct: 214 VAKVFAADPDYGNLGKLRYSIL-TESCPFFGIDDD---GVIRNVQPLTRHGGENCTLEIT 269 Query: 443 ATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 A DSG A V I I N F+ Y S+ E+ +G+ +L V A Sbjct: 270 AQDSGIPPLETPRPATVSIVIEPVENLK--FDVPVYEISIPENIILGSEILTVRAVAGSG 327 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 N + + I N A F I TG ITT +D E Y Sbjct: 328 --NRRNPRKIVYSIENIDGA---LSFKIGKHTGRITTRTHIDYEKTKEY 371 Score = 74.1 bits (174), Expect = 1e-12 Identities = 85/372 (22%), Positives = 137/372 (36%), Gaps = 23/372 (6%) Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 +LDRE + Y L + A + + + A F P Y + + G Sbjct: 52 ELDREVASGYNLTIKALNIHEN-KFRLAHIRIVVIDENDNAPTFPPSGYHTTIFTNVTEG 110 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + + A D D + + N + FSI + G L+ + + R + + V Sbjct: 111 QEIFRVNAIDVDTGDNANIRYHLLNHQQLFSIMPKTGV-LVKTKERFAIDRTRNFTVIVV 169 Query: 443 ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 A + G + V I + N P F Y V E +GT+V V A D D G Sbjct: 170 AIN-GEFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQVGTSVAKVFAADPDYGNLG 228 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++ YS+ +E F G I + L R L +TA+D G+P L Sbjct: 229 KLRYSILTESC---------PFFGIDDDGVIRNVQPLTRHGGENCTLEITAQDSGIPPLE 279 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG--RIHYEL 620 +S+V F +Y +I E+ ++G+ + V A +I Y + Sbjct: 280 TPRPATVSIVIEPVENLKFDVPVYEISIPENIILGSEILTVRAVAGSGNRRNPRKIVYSI 339 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 + D SF I +G I T +D E + P QS ++ + I Sbjct: 340 ENIDGAL-SFKIGKHTGRITTRTHIDYEKTKEYSFP--------PKQSCDLLAQVPYCHI 390 Query: 681 NDSPPVFESDCL 692 SP + + DCL Sbjct: 391 AHSPDLLDVDCL 402 Score = 34.3 bits (75), Expect = 1.4 Identities = 31/124 (25%), Positives = 48/124 (38%), Gaps = 3/124 (2%) Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEIL 783 + G++ + F L ++ A L+ +LD E Y L I+A + + + I+ Sbjct: 25 VTSGNEESIFKLINYPRNNSASLILQRELDREVA-SGYNLTIKALNIHENKFRLAHIRIV 83 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLN 843 V D NDNAP + + RV A D D D R N+ L + Sbjct: 84 VIDENDNAPTFPPSGYHTTIFTNVTEGQEIFRVNAIDVDTGDNANIRYHLLNHQQLFSIM 143 Query: 844 ETTG 847 TG Sbjct: 144 PKTG 147 >SB_28202| Best HMM Match : Cadherin (HMM E-Value=1.8e-29) Length = 242 Score = 133 bits (321), Expect = 2e-30 Identities = 76/196 (38%), Positives = 107/196 (54%), Gaps = 10/196 (5%) Query: 400 HYEITGGNT---RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456 H+ ++GGN S+ S NG L + PLD + ++VL +S T+ G V Sbjct: 54 HFNVSGGNFTFFNSSGSMFSINGNNLRVGSTPLDRETAAQHVLDISLTEGGTIKGFVKVT 113 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 +N+ D N+ P+F++ + SV E +GT L VSATD D G N+ +TYS+ A Sbjct: 114 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------A 166 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576 + + F IN +TGAI+ K LDRET Y LTV A+DGG P L+ TT V I V D ND Sbjct: 167 AGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAND 226 Query: 577 NEPVFKQQLYTANIME 592 N PV + + ++ E Sbjct: 227 NPPVIQDAVIRVSLSE 242 Score = 108 bits (259), Expect = 7e-23 Identities = 62/180 (34%), Positives = 98/180 (54%), Gaps = 8/180 (4%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G + + LDRE A++ + + T+ + + + VN++D ND P Sbjct: 71 MFSINGNN-LRVGSTPLDRETAAQHVLDISLTEGGT-----IKGFVKVTVNVLDINDETP 124 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 125 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 182 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P ++ + S+SE Sbjct: 183 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242 Score = 107 bits (258), Expect = 1e-22 Identities = 57/160 (35%), Positives = 89/160 (55%), Gaps = 3/160 (1%) Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRET + ++L ++ +GG ++ V ++V+D+ND P+F+ + ++ E +GT Sbjct: 86 LDRETAAQHVLDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 143 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V ATD D G N + Y + EEG F I+ +G I K LDRE+ + L + Sbjct: 144 VFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVM 202 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 A DGG PP +ST V I++ D ND+PPV + + +SE Sbjct: 203 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242 Score = 84.2 bits (199), Expect = 1e-15 Identities = 74/239 (30%), Positives = 116/239 (48%), Gaps = 29/239 (12%) Query: 115 VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTD-NPV 170 V+V TD SP L S A + +++ P+ TY VSV E ++ V D PV Sbjct: 1 VVVNVTDGGSPA---LKSRAMVVIDVT------PKPRNLTYDVSVLEGEANVQVMDLKPV 51 Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 ++ + G N + + M FSI+ + V LD E + L I Sbjct: 52 VSHFNVS----GGN----FTFFNSSGSM-FSINGNNLRVGSTP-LDRETAAQHVLDISLT 101 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 +GG+ ++ +N+ D+ND P F + F SV+E +G + V A D D G N+ Sbjct: 102 EGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANS 159 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 LTY++ GN + +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 160 ALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 214 Score = 83.8 bits (198), Expect = 2e-15 Identities = 54/155 (34%), Positives = 78/155 (50%), Gaps = 10/155 (6%) Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDRE+ A H L +GGT V V + + DIND P+F+S ++E +GT Sbjct: 86 LDRETAAQHVLDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 143 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + A D D G N+ + YSI G++ FS+ + G+ + LD E+ R +Y Sbjct: 144 VFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYT 198 Query: 765 LVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796 L + A PPL + V I V D NDN PV++D Sbjct: 199 LTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 233 Score = 75.8 bits (178), Expect = 5e-13 Identities = 57/164 (34%), Positives = 79/164 (48%), Gaps = 8/164 (4%) Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 S LDRET A++ L ++ T+GG T F + V + E E Sbjct: 83 STPLDRETAAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPL--FQSPSFNVSVNEIER 140 Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 GT +T++ATD D ++ L Y I GN G FSI N G I+VA+ LD + +Y Sbjct: 141 LGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSI--NNKTGAISVAKQLDRETRDQYT 198 Query: 439 LTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 LTV A D G + T V I + DAN+ PV ++A S+ E Sbjct: 199 LTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242 Score = 72.1 bits (169), Expect = 6e-12 Identities = 48/151 (31%), Positives = 70/151 (46%), Gaps = 22/151 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I Sbjct: 114 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 165 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 166 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 211 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161 +ST + + + D NDN P + VS+ E Sbjct: 212 NSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242 Score = 44.4 bits (100), Expect = 0.001 Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 12/173 (6%) Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 GE D P V H+++ GG+ + +S S+ + G++ V LD E+ + Sbjct: 39 GEANVQVMDLKP-VVSHFNVSGGNFTFFNSSGSMFSINGNNLR--VGSTPLDRETAAQHV 95 Query: 764 ELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDA 821 + + V+V + V D+ND P+ + F + N + V F V A D Sbjct: 96 LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDG 153 Query: 822 DV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 D L Y I +GN +N TG+++++ QL+ T+ V DG Sbjct: 154 DAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 206 >SB_4130| Best HMM Match : Cadherin (HMM E-Value=9.3e-29) Length = 322 Score = 124 bits (298), Expect = 1e-27 Identities = 105/328 (32%), Positives = 164/328 (50%), Gaps = 39/328 (11%) Query: 375 LAEDEPPGTPVVT-----LTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + E P GT V+ L A D+D ++L YEI + R FSI G IT A Sbjct: 3 VTEGSPQGTAVLDHKGSQLVAVATDQDISGDKLTYEIVETSARDVFSI--HPATGAITTA 60 Query: 427 QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + LD++ +Y + TDSG S A V+I++TD N+ APVF + Y A+V+ + Sbjct: 61 KVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYA 120 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDRE 542 GT V +V+ATD D N +T+SL+ + + F +NP TG +T + LL R+ Sbjct: 121 GTRVTMVTATDGDSAAN--LTFSLARQ--------DTELFAVNPLTGVVTVSNAALLRRD 170 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T Y + +T DG + + V I ++ ++ F ++ Y+A++ E V + + Sbjct: 171 T---YTIKLTVSDG---NHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSVDSELVT 224 Query: 603 VGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGV--IRTNKALDRESVATHDLKAVA 659 V A +G I Y ++P + F I P++GV IR LDRES+ + + A Sbjct: 225 VRALGYPIG--STITYTIINPSE----LFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQA 278 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVF 687 D PP + VH+++ D ND+ PVF Sbjct: 279 RDDSVPPNVAQAAVHVQVIDRNDNQPVF 306 Score = 105 bits (253), Expect = 4e-22 Identities = 100/327 (30%), Positives = 149/327 (45%), Gaps = 35/327 (10%) Query: 478 VFEDAPIGTTVL-------VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 V E +P GT VL V ATD D+ ++TY + + + F I+P T Sbjct: 3 VTEGSPQGTAVLDHKGSQLVAVATDQDIS-GDKLTYEIVETSARDV-------FSIHPAT 54 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 GAITT K+LD E Y + D G P LS DV+I V D+ND PVF Y A + Sbjct: 55 GAITTAKVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATV 114 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKALDRES 649 + GT V+ V ATD D N + + L +D E F ++P +GV+ +N AL R Sbjct: 115 YLPSYAGTRVTMVTATDGDSAAN--LTFSLARQDTE--LFAVNPLTGVVTVSNAALLRRD 170 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 T+ +K DG ++ V I+ E++ S F + + E + + + + Sbjct: 171 --TYTIKLTVSDGN---HTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSVDSELVTV 225 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 RA G + + Y+I + S F + G + DLD ES Y+++++A Sbjct: 226 RALGYPIG--STITYTII--NPSELFHIVPSTG--VMSIRAGFDLDRES-IDAYQVIVQA 278 Query: 770 ---ASPPLWNDVRVEILVTDVNDNAPV 793 + PP V + V D NDN PV Sbjct: 279 RDDSVPPNVAQAAVHVQVIDRNDNQPV 305 Score = 91.9 bits (218), Expect = 7e-18 Identities = 87/329 (26%), Positives = 146/329 (44%), Gaps = 28/329 (8%) Query: 266 VSENVPIGYSIV-----RVQAYDADEGVNAE-LTYTMTDKDYTGNVDLPITIDPRSGWVY 319 V+E P G +++ ++ A D+ ++ + LTY + + T D+ +I P +G + Sbjct: 3 VTEGSPQGTAVLDHKGSQLVAVATDQDISGDKLTYEIVE---TSARDV-FSIHPATGAIT 58 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 T+ LD E +Y + TD G+P SA A F Y + Sbjct: 59 TAKVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPS 118 Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 GT V +TATD D L + + +T F++ G ++TV+ +++ Y + Sbjct: 119 YAGTRVTMVTATDGDSAANLTFSLARQDTE-LFAVNPLTG--VVTVSNAALLRRDT-YTI 174 Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 ++ +D G + A V+I + + F Y+ASV E + + ++ V A +G Sbjct: 175 KLTVSD-GNHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIG 233 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETMSGYLLTVTARDGG 557 + ITY+ + + + F I P TG +I LDRE++ Y + V ARD Sbjct: 234 --STITYT---------IINPSELFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDS 282 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 VP V + V+D NDN+PVF Y Sbjct: 283 VPPNVAQAAVHVQVIDRNDNQPVFINSPY 311 Score = 89.0 bits (211), Expect = 5e-17 Identities = 82/303 (27%), Positives = 126/303 (41%), Gaps = 20/303 (6%) Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 ATD D+ + + Y I+ + + FSI +G ++ K LDYE Y I+ D G+P Sbjct: 25 ATDQDISGDK-LTYEIVETSARDVFSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP 83 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 S + I++ D+ND AP F S + +V G + V A D D N LT++ Sbjct: 84 RLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN--LTFS 141 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXX 353 + +D +L ++P +G V S L R+T Y + +T +DG +A A Sbjct: 142 LARQD----TEL-FAVNPLTGVVTVSNAALLRRDT---YTIKLTVSDGN---HTAHARVR 190 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413 F Y + E + +VT+ A + + Y I N F Sbjct: 191 IRCENLPSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIGSTITYTII--NPSELFH 248 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFEN 471 I G I LD + Y + V A D + A V + + D N+ PVF N Sbjct: 249 IVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQPVFIN 308 Query: 472 APY 474 +PY Sbjct: 309 SPY 311 Score = 82.2 bits (194), Expect = 5e-15 Identities = 85/321 (26%), Positives = 146/321 (45%), Gaps = 35/321 (10%) Query: 32 VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91 V EG+ GT VL K G T + ++ D L E +DVF Sbjct: 3 VTEGSPQGTAVLDHK------GSQLVAVATDQDISGDKLTYE-------IVETSARDVFS 49 Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 I +GA+ T LD E +Y +K TD +P RLS+ A + +++ D ND P FS Sbjct: 50 IHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP---RLSAFADVKIHVTDINDIAPVFS 106 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 TY +V + + + ATD D AN + +++ +T++ F+++ L+G V+ Sbjct: 107 ASTYHATV--YLPSYAGTRVTMVTATDGDSAAN--LTFSLARQDTEL-FAVNPLTGVVT- 160 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 V + +Y + + DG + + ++ I ++ + +F + SV E V Sbjct: 161 VSNAALLRRDTYTIKLTVSDGNHTAHA---RVRIRCENLPSSDLQFSRKNYSASVREGVS 217 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT--IDPRSGWVYTSGQLDRETQ 329 + +V V+A + + +TYT+ + ++ +P T + R+G+ LDRE+ Sbjct: 218 VDSELVTVRALGYP--IGSTITYTIINPSELFHI-VPSTGVMSIRAGF-----DLDRESI 269 Query: 330 AKYQLLVTATDGGDPPRSATA 350 YQ++V A D PP A A Sbjct: 270 DAYQVIVQARDDSVPPNVAQA 290 Score = 64.5 bits (150), Expect = 1e-09 Identities = 77/256 (30%), Positives = 119/256 (46%), Gaps = 43/256 (16%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V D ND +PVF Y A+V + +GT V + ATD D N T L DT Sbjct: 92 KIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN----LTFSLARQDT 147 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128 ++F ++ +G + ++ A+L R R T +K T VSD Sbjct: 148 ------------------ELFAVNPLTGVVTVSNAALLR----RDTYTIKLT-----VSD 180 Query: 129 RLSSTATIHVNIIDDN--DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + TA V I +N + QFS K Y+ SV E +SV D+ ++ ++A +G S Sbjct: 181 G-NHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSV-DSELVT-VRALGYPIG--ST 235 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I Y II N F I +G +S+ LD E + +Y+++++A+D P + Sbjct: 236 ITYTII--NPSELFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVH 293 Query: 245 INIRDVNDNAPRFYTS 260 + + D NDN P F S Sbjct: 294 VQVIDRNDNQPVFINS 309 Score = 55.6 bits (128), Expect = 5e-07 Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 28/137 (20%) Query: 23 FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXX 82 F + Y ASVREG S + ++T++A IG + YTI +NP + Sbjct: 203 FSRKNYSASVREGVSVDSELVTVRALGYPIGST--ITYTI-------INPSE-------- 245 Query: 83 XXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140 +F I +G + RA LDRE + Y V+V+A D + P + + A +HV + Sbjct: 246 ------LFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPN---VAQAAVHVQV 296 Query: 141 IDDNDNYPQFSEKTYTV 157 ID NDN P F Y + Sbjct: 297 IDRNDNQPVFINSPYFI 313 >SB_10746| Best HMM Match : Cadherin (HMM E-Value=0) Length = 336 Score = 119 bits (286), Expect = 4e-26 Identities = 96/316 (30%), Positives = 151/316 (47%), Gaps = 15/316 (4%) Query: 374 ELAEDEPPGTPVVTLTATDADEDNRL-----HYEITGGNTRGRFSITSQNG--RGLITVA 426 ++ E++ PG V ++ TD + RL Y+I G G F I + G R I + Sbjct: 23 QVKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGP-ADGIFEINAATGVLRTKILLN 81 Query: 427 Q---PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + P + + + TD+GG S T ++ + D N+++P F + E AP Sbjct: 82 REKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAP 141 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + + A D+D+G N+ Y + + + ++F + + K LDRET Sbjct: 142 ERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRET 201 Query: 544 MSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y L + A DGG P S +V I+++D ND+ P F + YTA++ E+A GT + + Sbjct: 202 RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLR 261 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+G NG I + LD + E G F +D +G I TN LD E + + L VA D Sbjct: 262 VTAIDQDIGKNGEIMFYLD-ESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQ 320 Query: 663 GTPPQSSTVIVHIKIE 678 G P S V + I+ Sbjct: 321 G--PDSIPVRAQVTIK 334 Score = 118 bits (283), Expect = 9e-26 Identities = 87/268 (32%), Positives = 131/268 (48%), Gaps = 24/268 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSDRLSSTATIHVNIID 142 +F I+ +G L T+ L+REK+ + + +K T VS +T V ++D Sbjct: 64 IFEINAATGVLRTKILLNREKLPPSAQGDIFQIQIKVTTDTGGVS----ATIPTEVRVLD 119 Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202 ND+ P+F + + + E S + +A DAD+G NS Y I+ GN FS+ Sbjct: 120 INDHSPKFPQDFEELQISE--SAPERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSL 177 Query: 203 D--SLSGDVSLV-----KTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNA 254 S D+ V K LD E Y+LVI A DGG P RS ++ I I D ND++ Sbjct: 178 SLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHS 237 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P F + SV EN P G ++RV A D D G N E+ + + + G +D Sbjct: 238 PEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDESPERG----LFRMDEY 293 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGG 342 +G ++T+ LD E +++Y+L V A D G Sbjct: 294 TGEIWTNAVLDYEVKSEYRLTVVAQDQG 321 Score = 95.9 bits (228), Expect = 4e-19 Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 16/241 (6%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ VLD NDHSP F E + E A + +A D DIG N+ EY I Sbjct: 111 IPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRGN 170 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D L D+ + L+ LDRE Y +++ A D P+ Sbjct: 171 EDGL-------FSLSLKRFSPDMIYV-----YLVNTKRLDRETRDFYQLVIVAVDGGFPL 218 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S +++ I+D ND+ P+FS+ YT SV E+ + + ++ A D D+G N Sbjct: 219 PR--SGRKEVNITILDSNDHSPEFSKDFYTASVPEN--APNGTYLLRVTAIDQDIGKNGE 274 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I + + + F +D +G++ LDYE YRL + AQD G S Q+ I Sbjct: 275 IMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIK 334 Query: 247 I 247 + Sbjct: 335 V 335 Score = 91.5 bits (217), Expect = 9e-18 Identities = 82/249 (32%), Positives = 110/249 (44%), Gaps = 20/249 (8%) Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 Q+ VT GG SAT F E++++E P + A D Sbjct: 97 QIKVTTDTGGV---SATIPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALD 153 Query: 393 ADEDNRL--HYEITGGNTRGRFSITSQN-GRGLITV----AQPLDFKQERRYVLTVSATD 445 AD N Y I GN G FS++ + +I V + LD + Y L + A D Sbjct: 154 ADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVD 213 Query: 446 SG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 G RS V I I D+N+++P F YTASV E+AP GT +L V+A D D+G N Sbjct: 214 GGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNG 273 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +I + L F ++ TG I TN +LD E S Y LTV A+D G S+ Sbjct: 274 EIMFYLDESPERGL-------FRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIP 326 Query: 563 DTTDVEISV 571 V I V Sbjct: 327 VRAQVTIKV 335 Score = 87.0 bits (206), Expect = 2e-16 Identities = 94/318 (29%), Positives = 148/318 (46%), Gaps = 27/318 (8%) Query: 590 IMEDALVGTSVSQVGATDADVGLN---GRIHYELD-PKDREEGSFVIDPASGVIRTNKAL 645 + E+ G V V TD L G+I Y++ P D G F I+ A+GV+RT L Sbjct: 24 VKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGPAD---GIFEINAATGVLRTKILL 80 Query: 646 DRESV---ATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 +RE + A D+ + I T S+T+ +++ DIND P F D ISE++ Sbjct: 81 NREKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESA 140 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD---LDYE 757 P + RA D D G N++ Y I G++ FSL ++ S V +V+ LD E Sbjct: 141 PERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRE 200 Query: 758 SPRKKYELVIRAASP--PLWNDVRVEILVT--DVNDNAP-VMKDFQIIFNNYKDCFPVGP 812 + R Y+LVI A PL R E+ +T D ND++P KDF + + P G Sbjct: 201 T-RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTA--SVPENAPNGT 257 Query: 813 F-GRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 + RV A D D+ ++ + + L ++E TG + + L+ V + V Sbjct: 258 YLLRVTAIDQDIGKNGEIMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVA 317 Query: 870 TD-GVNEIKAMMQLSVRL 886 D G + I Q+++++ Sbjct: 318 QDQGPDSIPVRAQVTIKV 335 Score = 84.6 bits (200), Expect = 1e-15 Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 10/235 (4%) Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 D G S + T+ + + D+ND++P+F + +SE+ P +A DAD G N+ Sbjct: 103 DTGGVSATIPTE--VRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNS 160 Query: 291 ELTYTMTDKDYTGNVDLPIT-IDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDP-PR 346 Y + + G L + P +VY + +LDRET+ YQL++ A DGG P PR Sbjct: 161 IQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPR 220 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404 S F Y + E+ P GT ++ +TA D D ++ + + + Sbjct: 221 SGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLD 280 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 RG F + G I LD++ + Y LTV A D G S Q+ I Sbjct: 281 ESPERGLFRMDEYTGE--IWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTI 333 >SB_4448| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 245 Score = 117 bits (281), Expect = 2e-25 Identities = 66/196 (33%), Positives = 106/196 (54%), Gaps = 8/196 (4%) Query: 105 LDREKVAR-YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 LDRE +T+ V ATDQ + ++LS+T + + D ND+ P F+++ + +V ED Sbjct: 16 LDRETSPNSFTITVLATDQGA---NKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSED- 71 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 V V+ + ATD D G N+ + + + GN F +D G V + L+Y +SY Sbjct: 72 -VRPGYVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVFDILNYTLRKSY 130 Query: 224 RLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 L + D G P S ++ +LI I D NDNAP F + + ++V+E++ +G +V V A Sbjct: 131 NLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTA 190 Query: 282 YDADEGVNAELTYTMT 297 D D G NA+ + +T Sbjct: 191 VDYDSGDNAKFVFDIT 206 Score = 113 bits (273), Expect = 1e-24 Identities = 69/188 (36%), Positives = 99/188 (52%), Gaps = 11/188 (5%) Query: 437 YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 + +TV ATD G S T + I +TDAN++APVF + +V ED G V VSAT Sbjct: 25 FTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSAT 84 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D+D G NA++ + ++ NE A F ++P G + +L+ Y LTVT Sbjct: 85 DTDTGPNAELEFVVTH--GNEPAA-----FYVDPSKGTVHVFDILNYTLRKSYNLTVTVS 137 Query: 555 DGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 D G+P LSD + V I++ D NDN P+F Y + ED VG+ V V A D D G Sbjct: 138 DRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGD 197 Query: 613 NGRIHYEL 620 N + +++ Sbjct: 198 NAKFVFDI 205 Score = 110 bits (265), Expect = 1e-23 Identities = 74/218 (33%), Positives = 105/218 (48%), Gaps = 8/218 (3%) Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 S+ + + A D G+ S T I + D ND+AP F +F+ +VSE+V GY + V A Sbjct: 24 SFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSA 83 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 D D G NAEL + +T GN +DP G V+ L+ + Y L VT +D Sbjct: 84 TDTDTGPNAELEFVVTH----GNEPAAFYVDPSKGTVHVFDILNYTLRKSYNLTVTVSDR 139 Query: 342 GDPPRS--ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN- 397 G P S + A F+P QY +AED G+PVV +TA D D DN Sbjct: 140 GMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNA 199 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 + ++ITGGN F +N L+ V+ L + +R Sbjct: 200 KFVFDITGGNPNDLFESRPRNRIILVWVSCALGYPLDR 237 Score = 108 bits (259), Expect = 7e-23 Identities = 64/207 (30%), Positives = 102/207 (49%), Gaps = 4/207 (1%) Query: 537 KLLDRETM-SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 ++LDRET + + +TV A D G LS T I V D ND+ PVF ++++ + ED Sbjct: 14 EILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVR 73 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 G V+ V ATD D G N + + + E +F +DP+ G + L+ +++L Sbjct: 74 PGYVVTSVSATDTDTGPNAELEFVV-THGNEPAAFYVDPSKGTVHVFDILNYTLRKSYNL 132 Query: 656 KAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 D G P +S V I I D ND+ P+F + ++E+ +G+ + + A D Sbjct: 133 TVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVD 192 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETR 740 D G NA + I GG+ ++ F R Sbjct: 193 YDSGDNAKFVFDITGGNPNDLFESRPR 219 Score = 90.2 bits (214), Expect = 2e-17 Identities = 68/227 (29%), Positives = 103/227 (45%), Gaps = 10/227 (4%) Query: 324 LDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LDRET + + V ATD G S T F + ++ED PG Sbjct: 16 LDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPG 75 Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 V +++ATD D + L + +T GN F + +G + V L++ + Y LT Sbjct: 76 YVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPS--KGTVHVFDILNYTLRKSYNLT 133 Query: 441 VSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 V+ +D G + A V I ITDAN+ AP+F Y +V ED +G+ V+VV+A D Sbjct: 134 VTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDY 193 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 D G NA+ + ++ N+ + +I + LDRET Sbjct: 194 DSGDNAKFVFDITGGNPNDLFESRPRNRIILVWV-SCALGYPLDRET 239 Score = 77.0 bits (181), Expect = 2e-13 Identities = 61/186 (32%), Positives = 87/186 (46%), Gaps = 24/186 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH+PVF + + +V E G V ++ ATD D G NAE+E+ + T Sbjct: 47 IYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVV------TH 100 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV-SDR 129 E A F +D G + L+ Y + V +D+ PV SD Sbjct: 101 GNEPA-------------AFYVDPSKGTVHVFDILNYTLRKSYNLTVTVSDRGMPVLSD- 146 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S A + + I D NDN P F Y +V ED++V +PV+ + A D D G N+ + Sbjct: 147 -NSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAV-GSPVVV-VTAVDYDSGDNAKFVF 203 Query: 190 AIIGGN 195 I GGN Sbjct: 204 DITGGN 209 Score = 72.1 bits (169), Expect = 6e-12 Identities = 58/201 (28%), Positives = 92/201 (45%), Gaps = 12/201 (5%) Query: 645 LDRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 LDRE S + + +A D G S+T + I + D ND PVF +SE+ G Sbjct: 16 LDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPG 75 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + + A D D GPNA + + + G++ +F ++ +G+ V + D+ + RK Y Sbjct: 76 YVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGT-----VHVFDILNYTLRKSY 130 Query: 764 ELVIRAA--SPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 L + + P+ +D V I +TD NDNAP+ Q +D P V A Sbjct: 131 NLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTA 190 Query: 819 YDADVTDKLQYRI-LSGNNAN 838 D D D ++ ++G N N Sbjct: 191 VDYDSGDNAKFVFDITGGNPN 211 Score = 31.9 bits (69), Expect = 7.6 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANL 839 I VTD ND+APV +D P V A D D +L++ + GN Sbjct: 47 IYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTHGNEPAA 106 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ + G++ + LN + K + V+V+D Sbjct: 107 FYVDPSKGTVHVFDILNYTLRKSYNLTVTVSD 138 >SB_34938| Best HMM Match : Cadherin (HMM E-Value=1e-25) Length = 150 Score = 109 bits (263), Expect = 2e-23 Identities = 62/154 (40%), Positives = 86/154 (55%), Gaps = 7/154 (4%) Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 S NG L + PLD + +++L +S T+ G V +N+ D N+ P+F++ + Sbjct: 3 SINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFN 62 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 SV E +GT L VSATD D G N+ +TYS+ A + + F IN +TGAI+ Sbjct: 63 VSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISV 115 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 K LDRET Y LTV A+DGG P L+ TT V I Sbjct: 116 AKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAI 149 Score = 91.5 bits (217), Expect = 9e-18 Identities = 54/157 (34%), Positives = 85/157 (54%), Gaps = 8/157 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G + + LDRE A++ + + T+ + + + VN++D ND P Sbjct: 1 MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 54 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 55 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 112 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +S+ K LD E Y L + AQDGG P ++TT + I Sbjct: 113 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAI 149 Score = 90.2 bits (214), Expect = 2e-17 Identities = 49/138 (35%), Positives = 76/138 (55%), Gaps = 3/138 (2%) Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRET + ++L ++ +GG ++ V ++V+D+ND P+F+ + ++ E +GT Sbjct: 16 LDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 73 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V ATD D G N + Y + EEG F I+ +G I K LDRE+ + L + Sbjct: 74 VFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVM 132 Query: 659 AIDGGTPPQSSTVIVHIK 676 A DGG PP +ST V I+ Sbjct: 133 AQDGGEPPLNSTTAVAIQ 150 Score = 81.4 bits (192), Expect = 9e-15 Identities = 47/135 (34%), Positives = 74/135 (54%), Gaps = 6/135 (4%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD E + L I +GG+ ++ +N+ D+ND P F + F SV+E +G Sbjct: 16 LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 73 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 + V A D D G N+ LTY++ GN + +I+ ++G + + QLDRET+ +Y L Sbjct: 74 VFLTVSATDGDAGANSALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRETRDQYTL 129 Query: 335 LVTATDGGDPPRSAT 349 V A DGG+PP ++T Sbjct: 130 TVMAQDGGEPPLNST 144 Score = 66.9 bits (156), Expect = 2e-10 Identities = 46/141 (32%), Positives = 68/141 (48%), Gaps = 10/141 (7%) Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDRE+ A H L +GGT V V + + DIND P+F+S ++E +GT Sbjct: 16 LDRETAAQHILDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 73 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + A D D G N+ + YSI G++ FS+ + G+ + LD E+ R +Y Sbjct: 74 VFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYT 128 Query: 765 LVIRA---ASPPLWNDVRVEI 782 L + A PPL + V I Sbjct: 129 LTVMAQDGGEPPLNSTTAVAI 149 Score = 62.5 bits (145), Expect = 5e-09 Identities = 46/129 (35%), Positives = 62/129 (48%), Gaps = 6/129 (4%) Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 S LDRET A++ L ++ T+GG T F + V + E E Sbjct: 13 STPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPL--FQSPSFNVSVNEIER 70 Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 GT +T++ATD D ++ L Y I GN G FSI N G I+VA+ LD + +Y Sbjct: 71 LGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSI--NNKTGAISVAKQLDRETRDQYT 128 Query: 439 LTVSATDSG 447 LTV A D G Sbjct: 129 LTVMAQDGG 137 Score = 57.6 bits (133), Expect = 1e-07 Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 19/124 (15%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I Sbjct: 44 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 95 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P + Sbjct: 96 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 144 Query: 131 SSTA 134 ++ A Sbjct: 145 TAVA 148 Score = 42.3 bits (95), Expect = 0.005 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 6/99 (6%) Query: 778 VRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833 V+V + V D+ND P+ + F + N + V F V A D D L Y I + Sbjct: 40 VKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAA 97 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 GN +N TG+++++ QL+ T+ V DG Sbjct: 98 GNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 136 >SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0) Length = 645 Score = 106 bits (255), Expect = 2e-22 Identities = 128/464 (27%), Positives = 190/464 (40%), Gaps = 67/464 (14%) Query: 1049 GFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQ---GCSIDAAYTTAVCEL 1105 G+ G CE + + S +C G +CV R + G C G D +V E Sbjct: 198 GYKGRTCEGVGERCS------PGVCNKG-RCVNRGDTGFDCLCPVGFKGDRCQEGSVIE- 249 Query: 1106 RARSFPVSSFLTFPGLKRRH-RIHLKLKF-ATQTTSGLLLYNGR--YNERHDFLALELVS 1161 F V SF++FPG++ +I L ++F A + GLLLYNG+ + R DF+++ +V Sbjct: 250 -TPQFDVKSFMSFPGIQGALLKIKLSMRFMANDASDGLLLYNGQRLHPNRGDFVSIAIV- 307 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSL 1221 G + F + LG G++ I + N+ G WHTV E + R ++ILD V S Sbjct: 308 -------GGNVEFRYDLGYGRAVIRSKKNITVGQWHTVVAERYRRDGSLILDSEPAVKSQ 360 Query: 1222 AGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDF 1281 A GL A + VL I T+ ++G N+ F Sbjct: 361 APCCSVGLNLALPLYVGGVLNFE-TIDTD------------KVG-----------VNRGF 396 Query: 1282 VGCISDFYIDHKFIDL-NSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT-YICDC 1339 GCISD +D IDL NSYV G + C E C PC N C T Y+C C Sbjct: 397 KGCISDVAVDDNPIDLINSYVKHRG-IEQCTECLLPCQIEPCVNNGTCIPRGQTGYMCAC 455 Query: 1340 KEGHTGKDCA-DSTGP-PWRFGGDGMLSFNPLLR----PIQLPWLNALSIRTRQRDAFVM 1393 +G TGK+C GP R +G L F P R P+ S+ + + Sbjct: 456 GDGFTGKNCEFPLVGPGKNRTCMNGGLPFPPSGRVCDCPVGYAGKRCESVVQLEDSMSFL 515 Query: 1394 S---IQLKSGLLHYSYN---GETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVL 1447 +Q ++ +Y G + + DG WH +++ D ++ +D ++ Sbjct: 516 GDGYVQYPGSVMRRNYELGAGPAVLRSRRRVDDGQWHFVKVFRRSQDGALQIDDD--EIV 573 Query: 1448 MPMLANKIQG-QYIGKILIGGLDTTAGL-LASDVGFFEGCIQDV 1489 N + G I IGG D L F GC+ + Sbjct: 574 NGTSKNGARSLNTPGPIFIGGGDDVETLTYGKYAASFRGCVSGI 617 Score = 46.4 bits (105), Expect = 3e-04 Identities = 79/353 (22%), Positives = 124/353 (35%), Gaps = 38/353 (10%) Query: 1256 LDLTGPLQIGGLPNIPS--SFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEK 1313 L+L + +GG+ N F N+ F+GCIS +D N+ + C Sbjct: 154 LNLNQNMFLGGVANYSKIDRFSGFNRGFIGCISYIKVD------NNTIRPGYKGRTCEGV 207 Query: 1314 RSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDCAD-STGPPWRFGGDGMLSFNPL-- 1369 RCS C N C + DT + C C G G C + S +F +SF + Sbjct: 208 GERCSPGVC-NKGRCVNRGDTGFDCLCPVGFKGDRCQEGSVIETPQFDVKSFMSFPGIQG 266 Query: 1370 -LRPIQLPW-------LNALSIRTRQR----DAFVMSIQLKSGLLHYSYN---GETMYLP 1414 L I+L + L + QR +SI + G + + Y+ G + Sbjct: 267 ALLKIKLSMRFMANDASDGLLLYNGQRLHPNRGDFVSIAIVGGNVEFRYDLGYGRAVIRS 326 Query: 1415 MATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGL 1474 ++ G WH + + D S+ +D V + + +GG+ + Sbjct: 327 KKNITVGQWHTVVAERYRRDGSLILD-SEPAVKSQAPCCSVGLNLALPLYVGGVLNFETI 385 Query: 1475 LASDVGF---FEGCIQDVRI-GTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVT 1530 VG F+GCI DV + L+N + + C + C C+ Sbjct: 386 DTDKVGVNRGFKGCISDVAVDDNPIDLINSYVKHRGIEQCTECLLPCQIEPCVNNGTCIP 445 Query: 1531 SWDSS-TCTCEAGRVGPQCVSACELGPCGAARCVPDQ---TPKGYSCACEPGY 1579 + C C G G C +GP C+ P G C C GY Sbjct: 446 RGQTGYMCACGDGFTGKNCEFPL-VGPGKNRTCMNGGLPFPPSGRVCDCPVGY 497 Score = 33.1 bits (72), Expect = 3.3 Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 2/35 (5%) Query: 1547 QCVSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 +C+ C++ PC C+P + GY CAC G+T Sbjct: 427 ECLLPCQIEPCVNNGTCIP-RGQTGYMCACGDGFT 460 Score = 31.9 bits (69), Expect = 7.6 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%) Query: 1037 YPVTSFTCQCPEGFTGVNCETIL-TKASCEVDGDGSICRSGS 1077 +P + C CP G+ G CE+++ + S GDG + GS Sbjct: 484 FPPSGRVCDCPVGYAGKRCESVVQLEDSMSFLGDGYVQYPGS 525 >SB_40244| Best HMM Match : Cadherin (HMM E-Value=0) Length = 566 Score = 105 bits (253), Expect = 4e-22 Identities = 127/502 (25%), Positives = 210/502 (41%), Gaps = 65/502 (12%) Query: 129 RLSSTATIHVNII--DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 R TA++ V++ N N P+ + VSV E+ S D ++A I ATDAD ++ Sbjct: 37 RAQHTASLRVSVFVFPVNQNAPKIYPRHMVVSVYENASKGD--MVASINATDAD--SHDQ 92 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y ++ G +F ++S +G +S+V+ LD E Y+L + QD S S+ ++ I Sbjct: 93 LLYTLLAGGDG-RFQLNSSTGVLSVVEQLDRESTAQYKLFVLVQDRQSLPYSDYGEVDIT 151 Query: 247 IRDVNDNAPRFYTSLFQES------VSENVPIG--------YSIVRVQAYDADEGVNAEL 292 + DVNDN P+ QES ++EN Y +V A D + + Sbjct: 152 VIDVNDNQPQLSKDREQESSYNLTIIAENTLARPRLRSKHMYHVVVDDANDFPPSFSRQT 211 Query: 293 TYT-MTDKDYTG------NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--- 342 Y +T+ G N P T +S VY ++ + Y+ L+ G Sbjct: 212 YYAHVTEGTPVGTLVINLNASDPDTDSGKSHLVYRIIH-EKSSLESYRFLMDPESGDITT 270 Query: 343 ----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398 D R A+ M Q +E G + + A D DE + Sbjct: 271 QSEIDRERIASYNVSVKFILMEQLRFVRMKVQSGFSASESSAIGDVIARVHAEDKDEGSN 330 Query: 399 --LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--------- 447 + Y+IT GN G F + G +T+A+PLDF+ + Y LTV + + Sbjct: 331 AVITYQITLGNEDGNFLLHPMTGD--LTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARAR 388 Query: 448 -----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 +SD A+V + + DAN+ PVF + G +LVV A D D + Sbjct: 389 RQVLTSKSDEAIVTVKVNDANDNQPVFIKDVFVGGFVYKDYTGGAILVVKAIDKDSFASG 448 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMSGYLLTVTA--RDGGV 558 + Y +++ + A+ ++NP+TG ++ N + E Y L V A DG Sbjct: 449 PVIYRETNQSPSGAL-------LLNPRTGHVSLNLASIHVNEATKRYTLEVMASDNDGKF 501 Query: 559 PSLSDTTDVEISVVDVNDNEPV 580 P + T + ++ +++ V Sbjct: 502 PYNNSTKTANVVILQFTEDDNV 523 Score = 104 bits (249), Expect = 1e-21 Identities = 108/357 (30%), Positives = 161/357 (45%), Gaps = 50/357 (14%) Query: 540 DRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 DRE S Y LT+ A + P L + V D ND P F +Q Y A++ E VGT Sbjct: 165 DREQESSYNLTIIAENTLARPRLRSKHMYHVVVDDANDFPPSFSRQTYYAHVTEGTPVGT 224 Query: 599 SVSQVGATDADVGLNGRIH--YEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 V + A+D D +G+ H Y + + E F++DP SG I T +DRE +A+++ Sbjct: 225 LVINLNASDPDTD-SGKSHLVYRIIHEKSSLESYRFLMDPESGDITTQSEIDRERIASYN 283 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + I V +K++ F SE+S IG I + A D Sbjct: 284 VSVKFI-----LMEQLRFVRMKVQS-------------GFSASESSAIGDVIARVHAEDK 325 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----A 770 DEG NAV+ Y I G++ +F L G +L LD+E + Y L +R+ Sbjct: 326 DEGSNAVITYQITLGNEDGNFLLHPMTG----DLTIAKPLDFEY-KSVYTLTVRSFNIDP 380 Query: 771 SPPL-----------WNDVRVEILVTDVNDNAPV-MKDFQIIFNNYKDCFPVGPFGRVPA 818 S PL ++ V + V D NDN PV +KD + YKD + G V A Sbjct: 381 SSPLARARRQVLTSKSDEAIVTVKVNDANDNQPVFIKDVFVGGFVYKD-YTGGAILVVKA 439 Query: 819 YDAD--VTDKLQYRILSGNNANLILLNETTGSMTLS-PQLNTN-VPKLATMEVSVTD 871 D D + + YR + + + +LLN TG ++L+ ++ N K T+EV +D Sbjct: 440 IDKDSFASGPVIYRETNQSPSGALLLNPRTGHVSLNLASIHVNEATKRYTLEVMASD 496 Score = 89.8 bits (213), Expect = 3e-17 Identities = 94/353 (26%), Positives = 153/353 (43%), Gaps = 58/353 (16%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND P F Q Y A V EG GT V+ L A+D D + + + + + E Sbjct: 199 DANDFPPSFSRQTYYAHVTEGTPVGTLVINLNASDPDTDSGKS--HLVYRIIHEKSSLES 256 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 F +D SG + T++ +DRE++A Y V VK Sbjct: 257 YR-------------FLMDPESGDITTQSEIDRERIASYNVSVKF--------------- 288 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 I+ + + + ++ S E ++ D VIA++ A D D G+N+ I Y I G Sbjct: 289 -----ILMEQLRFVRMKVQS-GFSASESSAIGD--VIARVHAEDKDEGSNAVITYQITLG 340 Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA--QDGGSP----------SRSNTTQ 242 N F + ++GD+++ K LD+E Y L +R+ D SP S+S+ Sbjct: 341 NEDGNFLLHPMTGDLTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARARRQVLTSKSDEAI 400 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + + + D NDN P F +F G +I+ V+A D D + + Y T++ + Sbjct: 401 VTVKVNDANDNQPVFIKDVFVGGFVYKDYTGGAILVVKAIDKDSFASGPVIYRETNQSPS 460 Query: 303 GNVDLPITIDPRSGWVYTS-GQLD-RETQAKYQLLVTAT--DGGDPPRSATAT 351 G + ++PR+G V + + E +Y L V A+ DG P ++T T Sbjct: 461 G----ALLLNPRTGHVSLNLASIHVNEATKRYTLEVMASDNDGKFPYNNSTKT 509 Score = 83.8 bits (198), Expect = 2e-15 Identities = 110/401 (27%), Positives = 169/401 (42%), Gaps = 53/401 (13%) Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 DY G VD+ + ID S DRE ++ Y L + A + PR + Sbjct: 144 DY-GEVDITV-IDVNDNQPQLSK--DREQESSYNLTIIAENTLARPRLRSKHMYHVVVDD 199 Query: 360 XXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---RLHYEITGGNTR---GRF 412 F Y + E P GT V+ L A+D D D+ L Y I + RF Sbjct: 200 ANDFPPSFSRQTYYAHVTEGTPVGTLVINLNASDPDTDSGKSHLVYRIIHEKSSLESYRF 259 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472 + ++G IT +D +ER VS V+ + + + + + Sbjct: 260 LMDPESGD--ITTQSEID--RERIASYNVS------------VKFILMEQLRFVRMKVQS 303 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 ++AS E + IG + V A D D G NA ITY ++ + NE D F+++P TG Sbjct: 304 GFSAS--ESSAIGDVIARVHAEDKDEGSNAVITYQIT--LGNE-----DGNFLLHPMTGD 354 Query: 533 ITTNKLLDRETMSGYLLTVT------------ARDGGVPSLSDTTDVEISVVDVNDNEPV 580 +T K LD E S Y LTV AR + S SD V + V D NDN+PV Sbjct: 355 LTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARARRQVLTSKSDEAIVTVKVNDANDNQPV 414 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F + ++ + G ++ V A D D +G + Y + G+ +++P +G + Sbjct: 415 FIKDVFVGGFVYKDYTGGAILVVKAIDKDSFASGPVIYR-ETNQSPSGALLLNPRTGHVS 473 Query: 641 TNKALDRESVAT--HDLKAVAI--DGGTPPQSSTVIVHIKI 677 N A + AT + L+ +A DG P +ST ++ I Sbjct: 474 LNLASIHVNEATKRYTLEVMASDNDGKFPYNNSTKTANVVI 514 Score = 72.9 bits (171), Expect = 3e-12 Identities = 91/364 (25%), Positives = 147/364 (40%), Gaps = 44/364 (12%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 S DRE+ + Y + + A + + RL S HV + D ND P FS +TY V E Sbjct: 163 SKDREQESSYNLTIIAENTLA--RPRLRSKHMYHVVVDDANDFPPSFSRQTYYAHVTEGT 220 Query: 164 SVTDNPVIAKIKATDADV-GANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQ 219 V ++ + A+D D S + Y II + ++ F +D SGD++ +D E+ Sbjct: 221 PV--GTLVINLNASDPDTDSGKSHLVYRIIHEKSSLESYRFLMDPESGDITTQSEIDRER 278 Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 + SY + ++ L+ +R V + S SE+ IG I RV Sbjct: 279 IASYNVSVK------------FILMEQLRFVRMKVQSGF------SASESSAIGDVIARV 320 Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA- 338 A D DEG NA +TY +T GN D + P +G + + LD E ++ Y L V + Sbjct: 321 HAEDKDEGSNAVITYQIT----LGNEDGNFLLHPMTGDLTIAKPLDFEYKSVYTLTVRSF 376 Query: 339 -TDGGDP----------PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 D P +S A F+ + + G ++ Sbjct: 377 NIDPSSPLARARRQVLTSKSDEAIVTVKVNDANDNQPVFIKDVFVGGFVYKDYTGGAILV 436 Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 + A D D + Y T + G + + G + +A + +RY L V A+D Sbjct: 437 VKAIDKDSFASGPVIYRETNQSPSGALLLNPRTGHVSLNLASIHVNEATKRYTLEVMASD 496 Query: 446 SGGR 449 + G+ Sbjct: 497 NDGK 500 Score = 69.3 bits (162), Expect = 4e-11 Identities = 48/161 (29%), Positives = 80/161 (49%), Gaps = 12/161 (7%) Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASV 478 G + + +P + V+ D G TA +++++ N AP SV Sbjct: 10 GTLALVKPAKDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPKIYPRHMVVSV 69 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 +E+A G V ++ATD+D + Q+ Y+L +A D +F +N TG ++ + Sbjct: 70 YENASKGDMVASINATDADS--HDQLLYTL--------LAGGDGRFQLNSSTGVLSVVEQ 119 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 LDRE+ + Y L V +D SD +V+I+V+DVNDN+P Sbjct: 120 LDRESTAQYKLFVLVQDRQSLPYSDYGEVDITVIDVNDNQP 160 Score = 62.9 bits (146), Expect = 4e-09 Identities = 45/167 (26%), Positives = 74/167 (44%), Gaps = 4/167 (2%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F + +G + K VT +D G + + V + V VN N P Sbjct: 3 FAVEAMSGTLALVKPAKDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPKIYP 62 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 + ++ E+A G V+ + ATDAD + ++ Y L +G F ++ ++GV+ + Sbjct: 63 RHMVVSVYENASKGDMVASINATDADS--HDQLLYTLLAGG--DGRFQLNSSTGVLSVVE 118 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 LDRES A + L + D + P S V I + D+ND+ P D Sbjct: 119 QLDRESTAQYKLFVLVQDRQSLPYSDYGEVDITVIDVNDNQPQLSKD 165 Score = 59.3 bits (137), Expect = 4e-08 Identities = 41/148 (27%), Positives = 71/148 (47%), Gaps = 7/148 (4%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F+++++SG ++LVK ++ V+ +D G + + ++ + + VN NAP+ Y Sbjct: 3 FAVEAMSGTLALVKPAKDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPKIYP 62 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 SV EN G + + A DAD + +L YT+ D ++ +G + Sbjct: 63 RHMVVSVYENASKGDMVASINATDADS--HDQLLYTL-----LAGGDGRFQLNSSTGVLS 115 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRS 347 QLDRE+ A+Y+L V D P S Sbjct: 116 VVEQLDRESTAQYKLFVLVQDRQSLPYS 143 Score = 44.8 bits (101), Expect = 0.001 Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 9/166 (5%) Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAI--DGGTPPQSSTVIVHIKIEDINDSPPV 686 SF ++ SG + K + V ++ V D G ++++ V + + +N + P Sbjct: 2 SFAVEAMSGTLALVKPA--KDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPK 59 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 + + EN+ G + I A D D + Y++ G D F L + G Sbjct: 60 IYPRHMVVSVYENASKGDMVASINATDADSHDQLL--YTLLAGGDGR-FQLNSSTGV--L 114 Query: 747 ELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 +V +D + + K + LV S P + V+I V DVNDN P Sbjct: 115 SVVEQLDRESTAQYKLFVLVQDRQSLPYSDYGEVDITVIDVNDNQP 160 Score = 42.3 bits (95), Expect = 0.005 Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837 +RV + V VN NAP + ++ + Y++ + A DAD D+L Y +L+G + Sbjct: 44 LRVSVFVFPVNQNAPKIYPRHMVVSVYENASKGDMVASINATDADSHDQLLYTLLAGGDG 103 Query: 838 NLILLNETTGSMTLSPQLN 856 LN +TG +++ QL+ Sbjct: 104 R-FQLNSSTGVLSVVEQLD 121 Score = 38.7 bits (86), Expect = 0.066 Identities = 63/253 (24%), Positives = 101/253 (39%), Gaps = 37/253 (14%) Query: 31 SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVF 90 S E ++ G + + A D+D G NA + Y I TL ED F Sbjct: 306 SASESSAIGDVIARVHAEDKDEGSNAVITYQI------TLGNEDGN-------------F 346 Query: 91 RIDGRSGALLTRASLDREKVARYTVLVKA--TDQASP-------VSDRLSSTATIHVNII 141 + +G L LD E + YT+ V++ D +SP V S A + V + Sbjct: 347 LLHPMTGDLTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARARRQVLTSKSDEAIVTVKVN 406 Query: 142 DDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200 D NDN P F + + V +D + I +KA D D A+ + Y + Sbjct: 407 DANDNQPVFIKDVFVGGFVYKDYT---GGAILVVKAIDKDSFASGPVIYRETNQSPSGAL 463 Query: 201 SIDSLSGDVSLVKTLDY--EQVRSYRLVIRA--QDGGSPSRSNT-TQLLINIRDVNDNAP 255 ++ +G VSL + E + Y L + A DG P ++T T ++ ++ D+ Sbjct: 464 LLNPRTGHVSLNLASIHVNEATKRYTLEVMASDNDGKFPYNNSTKTANVVILQFTEDDNV 523 Query: 256 RFYTSLFQESVSE 268 R + E + E Sbjct: 524 RVIAGVPPEFIME 536 >SB_16935| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2204 Score = 102 bits (244), Expect = 5e-21 Identities = 146/584 (25%), Positives = 249/584 (42%), Gaps = 70/584 (11%) Query: 164 SVTDNPVIAKI--KATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221 SV +N + + K T DV + + Y ++ + + F +D+ G + +V+ +D+E Sbjct: 193 SVPENSPLGSVVGKLTTLDVDSRQSHSYTMVD-SAEGTFGVDNSLGVLVVVREMDFETHP 251 Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 + + + + D G+P S+ I++ DVN+ P L V EN + +I + + Sbjct: 252 QFFIQVMSTDSGTPPLSHVQNFTIDVMDVNE--PPTPPVLAPPVVYENASVHSTIGLLSS 309 Query: 282 YDADEGVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 +DAD N LTYT +TD T V+ S V S L ETQ++Y + V D Sbjct: 310 HDADADTN--LTYTLLTDARGTFRVE-------ESRLVLNS-PLSYETQSRYTITVQVRD 359 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP------GTPVVTLTATDAD 394 G+P A+ + ++ D+P GT V TLTA D D Sbjct: 360 NGNPILVASQAINVTVFDCNDPPTGVIFNGGSLDEYSDDPDVNGTRNGTHVGTLTAIDED 419 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 + +EI T+G N ++ A+ LDF+ + L + TD S T+ Sbjct: 420 AKDTHVFEIL---TQGS-PFRIHNSTVIVGNARRLDFESRNTWTLLIRVTDQVAASVTSS 475 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 ++I ++D N P + + S E+AP+GT + +S D D + +SL + SN Sbjct: 476 IRIFLSDINE--PPTMISLSSDSFSENAPVGTLIGSLSTQDPDA--QDRHRFSLETSSSN 531 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVD 573 +V+ + ++ NK++D ET+ L + V RD G + + ++ ++ + Sbjct: 532 -SVSINGSNLIV---------NKVVDFETVLNPLSIQVKVRDSGNLTRNQVFNITVTNSN 581 Query: 574 VNDNEPVFKQQL-----YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 QL T + E+ L G V+ + D D G ++ D Sbjct: 582 EAPTSIELTSQLSCSPGVTLCVPENKLAGYPVAYINVKDPDDG-------DVTTCDVMTD 634 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAI----DGGTPPQSSTVIVHIKIEDINDSP 684 F +I T + E++ + + +V I GG Q+ +I I D ND+P Sbjct: 635 EFFGIRDKELIVTGNT-NYEALTSDHVVSVGIFCRDKGGLSAQAD---YNISILDANDAP 690 Query: 685 -PVFESDCLTFYI-SENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 VF L+ YI S+++P+G+ +G D D HY I Sbjct: 691 TQVF----LSHYIASDSAPVGSLVGRFTVEDEDASD---THYCI 727 Score = 83.4 bits (197), Expect = 2e-15 Identities = 107/481 (22%), Positives = 190/481 (39%), Gaps = 45/481 (9%) Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D N P + +SV EN P+G + ++ D D +YTM D + + Sbjct: 177 DPGSNRPPSAILISSDSVPENSPLGSVVGKLTTLDVDS--RQSHSYTMVD-----SAEGT 229 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +D G + ++D ET ++ + V +TD G PP S P Sbjct: 230 FGVDNSLGVLVVVREMDFETHPQFFIQVMSTDSGTPPLSHVQNFTIDVMDVNEPPT--PP 287 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + E+ + + L++ DAD D L Y + + RG F + + + P Sbjct: 288 VLAPPVVYENASVHSTIGLLSSHDADADTNLTYTLL-TDARGTFRVEESR----LVLNSP 342 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTT 487 L ++ + RY +TV D+G A IN+T VF+ N P T +F + Sbjct: 343 LSYETQSRYTITVQVRDNGNPILVASQAINVT-------VFDCNDPPTGVIFNGGSLDEY 395 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAH---HDQQFVINPQTGAITTNKLLDRETM 544 + G + ++ + + V F I+ T + + LD E+ Sbjct: 396 SDDPDVNGTRNGTHVGTLTAIDEDAKDTHVFEILTQGSPFRIHNSTVIVGNARRLDFESR 455 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + + L + D S+ T+ + I + D+ NEP L + + E+A VGT + + Sbjct: 456 NTWTLLIRVTDQVAASV--TSSIRIFLSDI--NEPPTMISLSSDSFSENAPVGTLIGSLS 511 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH-DLKAVAIDGG 663 D D R + L+ S I+ ++ ++ NK +D E+V ++ D G Sbjct: 512 TQDPDA--QDRHRFSLETS--SSNSVSINGSNLIV--NKVVDFETVLNPLSIQVKVRDSG 565 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFE-------SDCLTFYISENSPIGTTIGEIRAHDPDE 716 ++ + +I + + N++P E S +T + EN G + I DPD+ Sbjct: 566 NLTRNQ--VFNITVTNSNEAPTSIELTSQLSCSPGVTLCVPENKLAGYPVAYINVKDPDD 623 Query: 717 G 717 G Sbjct: 624 G 624 Score = 82.6 bits (195), Expect = 4e-15 Identities = 159/664 (23%), Positives = 253/664 (38%), Gaps = 54/664 (8%) Query: 147 YPQ-FSEKTYTVSVDEDISVT-DNPVIAKIKATDADVGANSAIRY-----AIIGGNTQMQ 199 +PQ F + +++ I++T D+ I++ KA + VG A+ Y + + Sbjct: 770 FPQLFFIEVQNLNMSAQINITIDSSEISENKAPGSVVGRIHALSYDPTETLVFDLDDDCN 829 Query: 200 FSIDSLSGDVS----LVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 + SG+ + LV T LDYE Y +V+R + G+ R++ + I++ DV + Sbjct: 830 GTFALTSGNTANTRMLVTTRPLDYETRPQYTVVVRVR--GNAERTSFREFTISVLDVTE- 886 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P Y L SV EN +++V + E L +T D D L T Sbjct: 887 FPDDYLVLHHSSVVENT--AHALVGIVMLR--EPQMRHLAFTAID-DPDDAFMLQPTSFS 941 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 + + T+ LD E + + D S T Sbjct: 942 HTCKLLTARPLDYEKAQNHNITFNIRDTPYSQISVNQTFIIAVINVNEPPSAI--NLTNK 999 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITG--GNTRGRFSITSQNGRGLITVAQP--L 429 + E+ P GT + L D DE + + GRF ++ + VA P L Sbjct: 1000 NIVENSPRGTVIGRLIVEDPDEPFLPQSFVCNLRNDAYGRFMVSGLT----LKVADPRRL 1055 Query: 430 DFKQE--RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 DF+ ++ V D G S +NI + N + T V E+ G Sbjct: 1056 DFEGVGGAMCLIDVECRDQDGGSVQQQFVVNIMNENEAPTRVLSESGTFEVPENHSPGYI 1115 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V + A D D N TY L S + V F I+ ITT +L D E+ Y Sbjct: 1116 VAKLLAEDQDS--NDNFTYLLQSSKNTSNVP-----FTIHGNR-LITTARL-DYESRDTY 1166 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 ++ VT D G + S T + + V+DVND TA + E++ + T V ++ D Sbjct: 1167 VINVTCVDSG--NFSVTQALLVQVLDVNDVPSEIVVPPGTA-VTENSEMSTLVVELRTLD 1223 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGV-IRTNKALDRESVATHDLKAVAIDGGTP- 665 D+G + H + G+ + + + + + +D ESV L D G P Sbjct: 1224 EDLG---QTHKYIIHSQSPIGALELRETNKLHVADSSKIDYESVPYIHLTISTTDNGRPT 1280 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P + I+ I I D N+ P + L+ + EN+ +GT +G I DPD P A Sbjct: 1281 PLTKVTILKIPILDTNEKPTDIKLSPLS--MRENAAVGTIVGTITVIDPDTFPQAFTCLL 1338 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785 + D F + + + LDYE R + W + V Sbjct: 1339 V--DDAEGRFRIVHNNTKIDLAIGNGLALDYEKHRSHNITIKCTDGGGFWCQREFVLDVL 1396 Query: 786 DVND 789 D ND Sbjct: 1397 DAND 1400 Score = 81.0 bits (191), Expect = 1e-14 Identities = 115/485 (23%), Positives = 189/485 (38%), Gaps = 37/485 (7%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 LLT LD EK + + D +P S ++S T + +I+ N+ P T Sbjct: 946 LLTARPLDYEKAQNHNITFNIRD--TPYS-QISVNQTFIIAVINVNEP-PSAINLTNKNI 1001 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 V+ T VI ++ D D + + +F + L+ V+ + LD+E Sbjct: 1002 VENSPRGT---VIGRLIVEDPDEPFLPQSFVCNLRNDAYGRFMVSGLTLKVADPRRLDFE 1058 Query: 219 QVRSYRLVI----RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 V +I R QDGGS + Q ++NI + N+ R + V EN GY Sbjct: 1059 GVGGAMCLIDVECRDQDGGSVQQ----QFVVNIMNENEAPTRVLSESGTFEVPENHSPGY 1114 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 + ++ A D D N TY + T NV P TI + T+ +LD E++ Y + Sbjct: 1115 IVAKLLAEDQDS--NDNFTYLLQSSKNTSNV--PFTI--HGNRLITTARLDYESRDTYVI 1168 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 VT D G+ + PG + E+ T VV L D D Sbjct: 1169 NVTCVDSGNFSVTQALLVQVLDVNDVPSEIVVPPG---TAVTENSEMSTLVVELRTLDED 1225 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSD 451 Y I + G + N + + + +D++ LT+S TD+G + Sbjct: 1226 LGQTHKYIIHSQSPIGALELRETN-KLHVADSSKIDYESVPYIHLTISTTDNGRPTPLTK 1284 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 +++I I D N + +P S+ E+A +GT V ++ D D A + Sbjct: 1285 VTILKIPILDTNEKPTDIKLSP--LSMRENAAVGTIVGTITVIDPDTFPQAFTCLLVDDA 1342 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 + H++ + + AI LD E + +T+ DGG + + V Sbjct: 1343 EGRFRIVHNNTKIDL-----AIGNGLALDYEKHRSHNITIKCTDGG--GFWCQREFVLDV 1395 Query: 572 VDVND 576 +D ND Sbjct: 1396 LDAND 1400 Score = 79.4 bits (187), Expect = 4e-14 Identities = 168/683 (24%), Positives = 272/683 (39%), Gaps = 82/683 (12%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 VNI+++N+ + ++ T V E+ S ++AK+ A D D N + Sbjct: 1085 VNIMNENEAPTRVLSESGTFEVPENHS--PGYIVAKLLAEDQDSNDNFTYLLQSSKNTSN 1142 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 + F+I + LDYE +Y + + D G+ S T LL+ + DVND P Sbjct: 1143 VPFTIHG--NRLITTARLDYESRDTYVINVTCVDSGN--FSVTQALLVQVLDVND-VPSE 1197 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 +V+EN + +V ++ D D G + Y + + G ++L T Sbjct: 1198 IVVPPGTAVTENSEMSTLVVELRTLDEDLGQTHK--YIIHSQSPIGALELRET---NKLH 1252 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 V S ++D E+ L ++ TD G P T + + + E Sbjct: 1253 VADSSKIDYESVPYIHLTISTTDNGRPTPLTKVTILKIPILDTNEKPTDIKLS-PLSMRE 1311 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN-------GRGL-------- 422 + GT V T+T D D + + + GRF I N G GL Sbjct: 1312 NAAVGTIVGTITVIDPDTFPQAFTCLLVDDAEGRFRIVHNNTKIDLAIGNGLALDYEKHR 1371 Query: 423 ---ITV--AQPLDFKQERRYVLTV-SATDS-------GGRSDTAMVQ--INITDA--NNY 465 IT+ F +R +VL V A D+ R DT + Q +NI+ A N Sbjct: 1372 SHNITIKCTDGGGFWCQREFVLDVLDANDAPSNVIFIDARGDTTLDQARVNISSALATNT 1431 Query: 466 APVF---ENA-------PYTASVFEDAPIGT---TVLVVSATDSD--VGINA---QITYS 507 PV E+A Y + ED T ++S D+ V +NA Q +S Sbjct: 1432 VPVAAVNESAVAGITLVSYVHVIDEDTSHTAQKHTCGLISEEDAQLYVTVNAYRPQSDFS 1491 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 S E+ + +F+I P T +I + LD E + + + D G P LS + Sbjct: 1492 RRKRRSTES-SRVPTEFMIQPGTNSIVVREKLDYEARTNLTIFLKCTDNGSPQLSTVAYL 1550 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ++ V+DV E L + I E++ GT V + TD D + Y L+ + Sbjct: 1551 KVYVLDV--AEAPTDLTLSSLVIKENSPEGTLVGSITVTDPDSAPSA---YSLEVTSQGV 1605 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 ++ + V + LD E ++ + T Q T HI I DIN++P Sbjct: 1606 PFRLV--GNDVFVSRHPLDHERTPVITIQVTVREVFTSLQ-FTKSFHINISDINEAPSKV 1662 Query: 688 ESD-CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 D + + E+ +G TIG+ D D + + S+ GG +++ F++ R G+ Sbjct: 1663 TLDGKASVTVLESVTVGHTIGQFVVEDED-NYDKIFAISL-GGSNASDFAV--RDGA--- 1715 Query: 747 ELVTMVDLDYESPRKKYELVIRA 769 LV LD S +Y L +RA Sbjct: 1716 -LVVTSQLDAWS-IDRYTLAVRA 1736 Score = 75.4 bits (177), Expect = 6e-13 Identities = 157/753 (20%), Positives = 295/753 (39%), Gaps = 78/753 (10%) Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 TL+ + + F +D G L+ +D E ++ + V +TD +P Sbjct: 209 TLDVDSRQSHSYTMVDSAEGTFGVDNSLGVLVVVREMDFETHPQFFIQVMSTDSGTPP-- 266 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LS ++++D N+ P V E+ SV + I + + DAD N + Sbjct: 267 -LSHVQNFTIDVMDVNE--PPTPPVLAPPVVYENASV--HSTIGLLSSHDADADTN--LT 319 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y ++ + + F ++ + L L YE Y + ++ +D G+P + + + + Sbjct: 320 YTLLT-DARGTFRVEE--SRLVLNSPLSYETQSRYTITVQVRDNGNPILVASQAINVTVF 376 Query: 249 DVNDNAPR-FYTSLFQESVSENVPI-----GYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 D ND + + S++ + G + + A D D + + +T Sbjct: 377 DCNDPPTGVIFNGGSLDEYSDDPDVNGTRNGTHVGTLTAIDED-AKDTHVFEILTQGS-- 433 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 P I + V + +LD E++ + LL+ TD +A+ T Sbjct: 434 -----PFRIHNSTVIVGNARRLDFESRNTWTLLIRVTD----QVAASVTSSIRIFLSDIN 484 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 M +E+ P GT + +L+ D D +R + + ++ S NG L Sbjct: 485 EPPTMISLSSDSFSENAPVGTLIGSLSTQDPDAQDRHRFSLETSSSNS----VSINGSNL 540 Query: 423 ITVAQPLDFKQERRYV-LTVSATDSGGRSDTAMVQINITDANNYAPVFE-------NAPY 474 I V + +DF+ + + V DSG + + I +T++N E + Sbjct: 541 I-VNKVVDFETVLNPLSIQVKVRDSGNLTRNQVFNITVTNSNEAPTSIELTSQLSCSPGV 599 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 T V E+ G V ++ D D G + +++E D++ ++ TG Sbjct: 600 TLCVPENKLAGYPVAYINVKDPDDG-----DVTTCDVMTDEFFGIRDKELIV---TGNTN 651 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 L +S + + RD G LS D IS++D ND Y A+ + A Sbjct: 652 YEALTSDHVVS---VGIFCRDKG--GLSAQADYNISILDANDAPTQVFLSHYIAS--DSA 704 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 VG+ V + D D HY + + + +R K+L + Sbjct: 705 PVGSLVGRFTVEDEDAS---DTHYCILLTQNS----LFEILGLELRVKKSLKNATATRQP 757 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 ++ D + + + I+++++N S + + ISEN G+ +G I A Sbjct: 758 VRVWCYDRTSV--AFPQLFFIEVQNLNMSAQI-NITIDSSEISENKAPGSVVGRIHALSY 814 Query: 715 DEGPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---A 770 D P + + + DD N +F+L + ++ LVT LDYE+ R +Y +V+R A Sbjct: 815 D--PTETLVFDLD--DDCNGTFALTSGNTANTRMLVTTRPLDYET-RPQYTVVVRVRGNA 869 Query: 771 SPPLWNDVRVEIL-VTDVNDNAPVMKDFQIIFN 802 + + + +L VT+ D+ V+ ++ N Sbjct: 870 ERTSFREFTISVLDVTEFPDDYLVLHHSSVVEN 902 Score = 62.1 bits (144), Expect = 6e-09 Identities = 59/249 (23%), Positives = 112/249 (44%), Gaps = 23/249 (9%) Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 GYLL + ++ + +D N P + + ++ E++ +G+ V ++ Sbjct: 150 GYLLGINNITCQSSAIWSIIRAQCEDLDPGSNRPPSAILISSDSVPENSPLGSVVGKLTT 209 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D R + D EG+F +D + GV+ + +D E+ ++ ++ D GTP Sbjct: 210 LDVD----SRQSHSYTMVDSAEGTFGVDNSLGVLVVVREMDFETHPQFFIQVMSTDSGTP 265 Query: 666 PQSSTVIVHIKIEDIND--SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P S I + D+N+ +PPV + EN+ + +TIG + +HD D N + Sbjct: 266 PLSHVQNFTIDVMDVNEPPTPPVLAPP----VVYENASVHSTIGLLSSHDADADTN--LT 319 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780 Y++ D +F +E ++ LV L YE+ + +Y + ++ +P L + Sbjct: 320 YTLL-TDARGTFRVE------ESRLVLNSPLSYET-QSRYTITVQVRDNGNPILVASQAI 371 Query: 781 EILVTDVND 789 + V D ND Sbjct: 372 NVTVFDCND 380 Score = 60.9 bits (141), Expect = 1e-08 Identities = 81/377 (21%), Positives = 149/377 (39%), Gaps = 25/377 (6%) Query: 88 DVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 +V ID R L +A ++ +A TV V A ++++ L S +V++ID++ + Sbjct: 1404 NVIFIDARGDTTLDQARVNISSALATNTVPVAAVNESAVAGITLVS----YVHVIDEDTS 1459 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 + + + +T + IS D + + A + R + +F I + Sbjct: 1460 H---TAQKHTCGL---ISEEDAQLYVTVNAYRPQSDFSRRKRRSTESSRVPTEFMIQPGT 1513 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 + + + LDYE + + ++ D GSP S L + + DV + AP T L + Sbjct: 1514 NSIVVREKLDYEARTNLTIFLKCTDNGSPQLSTVAYLKVYVLDVAE-APTDLT-LSSLVI 1571 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 EN P G + + D D +A Y++ + T +P + +V + LD Sbjct: 1572 KENSPEGTLVGSITVTDPDSAPSA---YSL---EVTSQ-GVPFRLVGNDVFV-SRHPLDH 1623 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 E + VT + + + + G+ V + E G + Sbjct: 1624 ERTPVITIQVTVREVFTSLQFTKSFHINISDINEAPSKVTLDGKASVTVLESVTVGHTIG 1683 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 D D +++ GG+ F++ G + V LD RY L V ATD Sbjct: 1684 QFVVEDEDNYDKIFAISLGGSNASDFAVRD----GALVVTSQLDAWSIDRYTLAVRATDR 1739 Query: 447 GGRSDTAMVQINITDAN 463 GG S T+M+ + + + + Sbjct: 1740 GGLSTTSMITVIVKEVD 1756 Score = 59.3 bits (137), Expect = 4e-08 Identities = 112/462 (24%), Positives = 182/462 (39%), Gaps = 56/462 (12%) Query: 54 KNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113 +NA V TI L+++ + + + FR++ L+ + L E +RY Sbjct: 296 ENASVHSTIGLLSSHDADAD--TNLTYTLLTDARGTFRVE--ESRLVLNSPLSYETQSRY 351 Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDND--NYPQFSEKTY-TVSVDEDISVTDNPV 170 T+ V+ D +P+ L ++ I+V + D ND F+ + S D D++ T N Sbjct: 352 TITVQVRDNGNPI---LVASQAINVTVFDCNDPPTGVIFNGGSLDEYSDDPDVNGTRNGT 408 Query: 171 -IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 + + A D D G F I + + V + LD+E ++ L+IR Sbjct: 409 HVGTLTAIDEDAKDTHVFEILTQGS----PFRIHNSTVIVGNARRLDFESRNTWTLLIRV 464 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDADEG 287 D + S T+ + I + D+N+ P SL +S SEN P+G I + Q DA + Sbjct: 465 TD--QVAASVTSSIRIFLSDINE--PPTMISLSSDSFSENAPVGTLIGSLSTQDPDAQDR 520 Query: 288 VNAEL-TYTMTDKDYTGN-------VDLPITIDPRSGWVYT--SGQLDRETQAKYQLLVT 337 L T + G+ VD ++P S V SG L R +T Sbjct: 521 HRFSLETSSSNSVSINGSNLIVNKVVDFETVLNPLSIQVKVRDSGNLTRNQVFN----IT 576 Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397 T+ + P S T PG + + E++ G PV + D D+ + Sbjct: 577 VTNSNEAPTSIELTSQLSCS----------PG-VTLCVPENKLAGYPVAYINVKDPDDGD 625 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS--ATDSGGRSDTAMV 455 ++ T F I + LI +V++V D GG S A Sbjct: 626 VTTCDVM---TDEFFGIRDKE---LIVTGNTNYEALTSDHVVSVGIFCRDKGGLSAQADY 679 Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 I+I DAN+ + Y AS + AP+G+ V + D D Sbjct: 680 NISILDANDAPTQVFLSHYIAS--DSAPVGSLVGRFTVEDED 719 Score = 48.4 bits (110), Expect = 8e-05 Identities = 68/294 (23%), Positives = 105/294 (35%), Gaps = 25/294 (8%) Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + V I P + + +LD E + + + TD G P S A Sbjct: 1500 SSRVPTEFMIQPGTNSIVVREKLDYEARTNLTIFLKCTDNGSPQLSTVAYLKVYVLDVAE 1559 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGR 420 ++ E+ P GT V ++T TD D + E+T R G Sbjct: 1560 APTDLTLSSLVIK--ENSPEGTLVGSITVTDPDSAPSAYSLEVTSQGVPFRLV-----GN 1612 Query: 421 GLITVAQPLDFKQERRYVLTVSATDS---GGRSDTAMVQINITDANNY-APVFENAPYTA 476 + PLD ER V+T+ T T INI+D N + V + + Sbjct: 1613 DVFVSRHPLD--HERTPVITIQVTVREVFTSLQFTKSFHINISDINEAPSKVTLDGKASV 1670 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 +V E +G T+ D D N +++S SN + F + + GA+ Sbjct: 1671 TVLESVTVGHTIGQFVVEDED---NYDKIFAISLGGSNAS------DFAV--RDGALVVT 1719 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 LD ++ Y L V A D G S + V + VD+ N Q A + Sbjct: 1720 SQLDAWSIDRYTLAVRATDRGGLSTTSMITVIVKEVDLCANTSSCSPQATCARV 1773 Score = 41.9 bits (94), Expect = 0.007 Identities = 38/173 (21%), Positives = 60/173 (34%), Gaps = 19/173 (10%) Query: 1532 WDSSTCTCEAGRVGPQC---VSACELGPC---GAARCVPDQTPKGYSCACEPGYT--LTT 1583 W + TC C+ G P C ++ C PC G++RC + G+ C C G+T Sbjct: 1820 WKNYTCPCKPGWSPPNCKADINECLSNPCNSSGSSRC--ENLENGFQCTCRAGFTGKYCE 1877 Query: 1584 SGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHCKENHYKPEGTAECL 1642 + + K+ C G C + +C+ ++ C + GT Sbjct: 1878 TDVDDCEKDSCLNGGLCVDKTNGFICVCKEPFIGVNCDTDDTICRQNASICPHNGTCISY 1937 Query: 1643 P-------CQCYAA-GSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPN 1687 P C C S+ + C G C+P D C + PN Sbjct: 1938 PEDATKHTCLCSIPWSSDCNGCALGYGGADCKPCQYPWTGDNCLQDWRNCEPN 1990 Score = 40.3 bits (90), Expect = 0.022 Identities = 50/169 (29%), Positives = 61/169 (36%), Gaps = 20/169 (11%) Query: 1526 SKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCAC-EP--G 1578 S+C + CTC AG G C V CE C CV D+T G+ C C EP G Sbjct: 1854 SRCENLENGFQCTCRAGFTGKYCETDVDDCEKDSCLNGGLCV-DKT-NGFICVCKEPFIG 1911 Query: 1579 YTLTTSGCI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEG 1637 T I CP C D T+ + C+ Y G Sbjct: 1912 VNCDTDDTICRQNASICP----HNGTCISYPEDATKHTCLCSIPWSSDCNGCALGY---G 1964 Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686 A+C PCQ Y +N C C P + G C +N YA V P Sbjct: 1965 GADCKPCQ-YPWTGDN--CLQDWRNCEPNPCLHGGTCYPLSNEYACVCP 2010 Score = 37.1 bits (82), Expect = 0.20 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 9/86 (10%) Query: 1507 VRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV----GPQC--VSACELGPCGAA 1560 V + C +C S+ P +CV + S C C +G + G C V+ C G Sbjct: 26 VNNTCDDVNECQSSLNPCSQRCVNTRGSLYCACSSGFLLLGDGFTCRDVNECSQSGHGCE 85 Query: 1561 R-CVPDQTPKGYSCACEPGYTLTTSG 1585 + C+ T Y+C CE GY L +G Sbjct: 86 QHCM--NTVGSYTCICELGYKLGQNG 109 Score = 36.3 bits (80), Expect = 0.35 Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 19/126 (15%) Query: 1528 CVTSWDSSTCTCEAG----RVGPQC--VSACE--LGPCGAARCVPDQTPKGYSCACEPGY 1579 C+ + S TCTC +G V C V+ C+ L PC + RCV T CAC G+ Sbjct: 6 CINTIGSFTCTCASGLIYNPVNNTCDDVNECQSSLNPC-SQRCV--NTRGSLYCACSSGF 62 Query: 1580 TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN-----KENGKCHCKENHYK 1634 L G EC G C + Y C +NG+ + + Sbjct: 63 LLLGDGFTCRDVNECS---QSGHGCEQHCMNTVGSYTCICELGYKLGQNGRSCERVDCGI 119 Query: 1635 PEGTAE 1640 PEGT+E Sbjct: 120 PEGTSE 125 Score = 35.9 bits (79), Expect = 0.47 Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 17/114 (14%) Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 P SC C G+T +G I + + C P + G C D G+ +N C Sbjct: 1775 PGRASCTCRVGFT--GNGHICNDIDFCAPNPCHPDNTIGECQ-DGFGGW------KNYTC 1825 Query: 1627 HCKENHYKPEGTA---ECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACD 1675 CK P A ECL C ++GS S CE QC CR G G+ C+ Sbjct: 1826 PCKPGWSPPNCKADINECLSNPCNSSGS--SRCENLENGFQCTCRAGFTGKYCE 1877 Score = 35.9 bits (79), Expect = 0.47 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 10/109 (9%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGI-LCQGCSIDAAYTT 1100 F C C GFTG CET + CE D C +G CV + G I +C+ I T Sbjct: 1863 FQCTCRAGFTGKYCETDVD--DCEKDS----CLNGGLCVDKTNGFICVCKEPFIGVNCDT 1916 Query: 1101 --AVCELRARSFPVS-SFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG 1146 +C A P + + +++P +H + +++ L Y G Sbjct: 1917 DDTICRQNASICPHNGTCISYPEDATKHTCLCSIPWSSDCNGCALGYGG 1965 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/39 (35%), Positives = 17/39 (43%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C C NG C D + +IC CKE G +C Sbjct: 1876 CETDVDDCEKDSCLNGGLCVDKTNGFICVCKEPFIGVNC 1914 Score = 32.7 bits (71), Expect = 4.4 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 1310 CPEKRSRCSSAPCYNG--AECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC + + C +L + + C C+ G TGK C Sbjct: 1836 CKADINECLSNPCNSSGSSRCENLENGFQCTCRAGFTGKYC 1876 >SB_21336| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 120 Score = 101 bits (243), Expect = 6e-21 Identities = 56/126 (44%), Positives = 74/126 (58%), Gaps = 7/126 (5%) Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P+F++ + SV E +GT L VSATD D G N+ +TYS+ AV + + F I Sbjct: 2 PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------AVGNEEGFFSI 54 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 N +TGAI+ K LDRET Y LTV A+DGG P L+ TT V I V D NDN PV + + Sbjct: 55 NNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVI 114 Query: 587 TANIME 592 ++ E Sbjct: 115 QVSLSE 120 Score = 92.3 bits (219), Expect = 5e-18 Identities = 49/121 (40%), Positives = 70/121 (57%), Gaps = 2/121 (1%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 2 PLFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTG 59 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P ++ Q S+S Sbjct: 60 AISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLS 119 Query: 268 E 268 E Sbjct: 120 E 120 Score = 82.2 bits (194), Expect = 5e-15 Identities = 44/120 (36%), Positives = 64/120 (53%), Gaps = 1/120 (0%) Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P+F+ + ++ E +GT V ATD D G N + Y + EEG F I+ +G Sbjct: 2 PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AVGNEEGFFSINNKTGA 60 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 I K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV + + +SE Sbjct: 61 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 120 Score = 65.7 bits (153), Expect = 5e-10 Identities = 45/119 (37%), Positives = 62/119 (52%), Gaps = 6/119 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F + V + E E GT +T++ATD D ++ L Y I GN G FSI N G I Sbjct: 4 FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSIN--NKTGAI 61 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 +VA+ LD + +Y LTV A D G + T V I + DAN+ PV ++A S+ E Sbjct: 62 SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 120 Score = 64.9 bits (151), Expect = 9e-10 Identities = 36/95 (37%), Positives = 55/95 (57%), Gaps = 4/95 (4%) Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P F + F SV+E +G + V A D D G N+ LTY++ GN + +I+ + Sbjct: 2 PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----VGNEEGFFSINNK 57 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 +G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 58 TGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 92 Score = 60.5 bits (140), Expect = 2e-08 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 8/115 (6%) Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 P+F+S ++E +GT + A D D G N+ + YSI G++ FS+ + G+ Sbjct: 2 PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA- 60 Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796 + LD E+ R +Y L + A PPL + V I V D NDN PV++D Sbjct: 61 ---ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 111 Score = 58.4 bits (135), Expect = 8e-08 Identities = 42/142 (29%), Positives = 64/142 (45%), Gaps = 22/142 (15%) Query: 20 SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79 +P+F+ + SV E GT LT+ ATD D G N+ + Y+I + + Sbjct: 1 TPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGF--------- 51 Query: 80 XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139 F I+ ++GA+ LDRE +YT+ V A D P L+ST + + Sbjct: 52 ----------FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PLNSTTAVAIQ 98 Query: 140 IIDDNDNYPQFSEKTYTVSVDE 161 + D NDN P + VS+ E Sbjct: 99 VGDANDNPPVIQDAVIQVSLSE 120 Score = 32.7 bits (71), Expect = 4.4 Identities = 16/53 (30%), Positives = 24/53 (45%) Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 DA L Y I GN +N TG+++++ QL+ T+ V DG Sbjct: 32 DAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 84 >SB_36411| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 654 Score = 96.7 bits (230), Expect = 2e-19 Identities = 62/179 (34%), Positives = 93/179 (51%), Gaps = 15/179 (8%) Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N + PVF++ Y SV E++P G++VL V+ATD D G N ++ Y L+ +NEA D Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLA---TNEA----DM 282 Query: 523 QFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 F ++ +G I T+ +LD E + Y VTA D G P +T V ++++DVNDN P Sbjct: 283 PFTVDGLSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCP 342 Query: 580 VFKQQLYTA-NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 VF + T N+ GT + + TD D G N + Y + G +D +G Sbjct: 343 VFDPSIRTTYNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSVS----ANGVIAVDAVTG 397 Score = 91.1 bits (216), Expect = 1e-17 Identities = 53/156 (33%), Positives = 85/156 (54%), Gaps = 5/156 (3%) Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 N + PVF+ Y +++E++ G+SV +V ATD D G NG + Y L + + F +D Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADM-PFTVDG 288 Query: 635 ASGVIRTNKALDRESVATHDL---KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 SG I T+ LD E++ L A D G P + ++ V++ + D+ND+ PVF+ Sbjct: 289 LSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFDPSI 348 Query: 692 LTFY-ISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 T Y +S ++ GT + I D D G N++V YS+ Sbjct: 349 RTTYNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSV 384 Score = 86.6 bits (205), Expect = 3e-16 Identities = 63/202 (31%), Positives = 98/202 (48%), Gaps = 29/202 (14%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 N H PVF+ Y SV E + G++VL + ATD+D G+N EV Y + AD Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADM------- 282 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSST 133 F +DG SG ++T + LD E + R YT V A+D P+ + +ST Sbjct: 283 ------------PFTVDGLSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPM--KFAST 328 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 ++VN++D NDN P F T + + + + I TD D G NS + Y++ Sbjct: 329 R-VYVNLLDVNDNCPVFDPSIRT-TYNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSVSA 386 Query: 194 GNTQMQFSIDSLSGDVSLVKTL 215 ++D+++G +SL+ L Sbjct: 387 NGV---IAVDAVTGSLSLIGQL 405 Score = 82.2 bits (194), Expect = 5e-15 Identities = 49/154 (31%), Positives = 79/154 (51%), Gaps = 6/154 (3%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F Y VSV E+ S + V+ ++ ATD D G N +RY + M F++D LSG Sbjct: 234 PVFQSTYYNVSVVEN-SPPGSSVL-RVNATDEDSGRNGEVRYFLATNEADMPFTVDGLSG 291 Query: 208 DVSLVKTLDYEQV---RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL-FQ 263 ++ LDYE + Y + A D G P + +T++ +N+ DVNDN P F S+ Sbjct: 292 EIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFDPSIRTT 351 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 ++S + G + + D D G N+ + Y+++ Sbjct: 352 YNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSVS 385 Score = 70.5 bits (165), Expect = 2e-11 Identities = 49/148 (33%), Positives = 68/148 (45%), Gaps = 8/148 (5%) Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N + P F ++ + SV EN P G S++RV A D D G N E+ Y + T D+P T Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLA----TNEADMPFT 285 Query: 311 IDPRSGWVYTSGQLDRETQAK---YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +D SG + TS LD E + Y VTA+D G P + A+ F Sbjct: 286 VDGLSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFD 345 Query: 368 PG-QYEVELAEDEPPGTPVVTLTATDAD 394 P + L+ PGT + +T TD D Sbjct: 346 PSIRTTYNLSVHTAPGTQLDVITTTDKD 373 Score = 66.5 bits (155), Expect = 3e-10 Identities = 46/155 (29%), Positives = 78/155 (50%), Gaps = 14/155 (9%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F Y V + E+ PPG+ V+ + ATD D + + Y + F++ +G I Sbjct: 236 FQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADMPFTVDGLSGE--I 293 Query: 424 TVAQPLDFK---QERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE---NAPYT 475 + LD++ ++ Y V+A+D+G + + V +N+ D N+ PVF+ Y Sbjct: 294 VTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFDPSIRTTYN 353 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 SV AP GT + V++ TD D G N+ + YS+S+ Sbjct: 354 LSV-HTAP-GTQLDVITTTDKDAGYNSIVIYSVSA 386 Score = 64.9 bits (151), Expect = 9e-10 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 11/181 (6%) Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 N PPVF+S + ENSP G+++ + A D D G N V Y + + F+++ Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADMPFTVDGL 289 Query: 741 QGSDKAELVTMVDLDYES-PRKK-YELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM- 794 G E+VT LDYE+ PRK Y + A+ P + RV + + DVNDN PV Sbjct: 290 SG----EIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFD 345 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 + +N P + D D I S + +I ++ TGS++L Q Sbjct: 346 PSIRTTYNLSVHTAPGTQLDVITTTDKDAGYN-SIVIYSVSANGVIAVDAVTGSLSLIGQ 404 Query: 855 L 855 L Sbjct: 405 L 405 Score = 41.9 bits (94), Expect = 0.007 Identities = 63/233 (27%), Positives = 87/233 (37%), Gaps = 57/233 (24%) Query: 1517 CMLSICPPYSKCVTSWD---SSTCTCEAGRVGPQC--VSACE-LGPCGA-ARCVPDQTPK 1569 C + C S+C + D S+TC C G G +C V+ C G C CV D+ Sbjct: 73 CAVPDCAAVSQCSSHGDCVASNTCRCHPGYQGSRCSEVADCSSFGNCSFHGECVIDRGGN 132 Query: 1570 GYSCACEPGYT---LTTSGCIE----SGKEECPGGWWGGSACGPCACDVTRGYH-PHCNK 1621 +C C G++ + CI+ S + EC G C CDV GY P C+ Sbjct: 133 A-TCRCYTGFSGSECQLASCIKVKNCSNRGEC-------FESGFCKCDV--GYTGPDCSN 182 Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 + C+ +Y C C S+ C A C C PG G +C+ A Sbjct: 183 NS----CEAINY-------CSDCTAVQECSKRGYC-MAPDTCECYPGWDGPSCNKKA--- 227 Query: 1682 AEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDE 1734 TPN V + T + V + + PPGSS DE Sbjct: 228 ---TPNLHPPV--------------FQSTYYNVSVVENSPPGSSVLRVNATDE 263 Score = 39.9 bits (89), Expect = 0.029 Identities = 31/122 (25%), Positives = 41/122 (33%), Gaps = 7/122 (5%) Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP-CACDVTRGYHPHCNKENGKCHCKE 1630 SCA + Y C+ + + EC GW G S P CA H C N C C Sbjct: 43 SCA-DLDYCSGRGSCVNAYRCECNSGWTGISCAVPDCAAVSQCSSHGDCVASN-TCRCHP 100 Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSC---EAATGQCHCRPGVIGRACDACANAYAEVTPN 1687 Y+ +E C + S + C C C G G C + + N Sbjct: 101 G-YQGSRCSEVADCSSFGNCSFHGECVIDRGGNATCRCYTGFSGSECQLASCIKVKNCSN 159 Query: 1688 SG 1689 G Sbjct: 160 RG 161 Score = 39.5 bits (88), Expect = 0.038 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 10/77 (12%) Query: 1513 SRADCMLSICPPYSKCVTS---WDSSTCTCEAGRVGPQCV-SACE-LGPCGAARCVPDQT 1567 S ++C L+ C C ++S C C+ G GP C ++CE + C V + + Sbjct: 142 SGSECQLASCIKVKNCSNRGECFESGFCKCDVGYTGPDCSNNSCEAINYCSDCTAVQECS 201 Query: 1568 PKGY-----SCACEPGY 1579 +GY +C C PG+ Sbjct: 202 KRGYCMAPDTCECYPGW 218 Score = 35.5 bits (78), Expect = 0.62 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 5/55 (9%) Query: 11 INVLDCNDHSPVFE---MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 +N+LD ND+ PVF+ Y SV + GT + + TD+D G N+ V Y++ Sbjct: 332 VNLLDVNDNCPVFDPSIRTTYNLSVH--TAPGTQLDVITTTDKDAGYNSIVIYSV 384 Score = 31.9 bits (69), Expect = 7.6 Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 3/41 (7%) Query: 1315 SRCSSAPCYNGAECS---DLWDTYICDCKEGHTGKDCADST 1352 S C A C CS + +++ C C G+TG DC++++ Sbjct: 144 SECQLASCIKVKNCSNRGECFESGFCKCDVGYTGPDCSNNS 184 >SB_15158| Best HMM Match : Cadherin (HMM E-Value=7.5e-23) Length = 390 Score = 96.3 bits (229), Expect = 3e-19 Identities = 63/161 (39%), Positives = 85/161 (52%), Gaps = 3/161 (1%) Query: 556 GGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 GGV S + T V I V DV+D VF YTA + E + G V+ V A D D+ LN Sbjct: 204 GGVNGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNK 263 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 + Y +D +FVI +GVI NK LDRE+VA ++L+ AI T ++ V Sbjct: 264 PVSYFIDQVTNPGEAFVIINTTGVITVNKPLDRETVAFYNLRVGAI--STIHKAVFATVQ 321 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 I I DIND+ P F + + + ENSP G T+ + A D D Sbjct: 322 ITITDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDAD 362 Score = 87.8 bits (208), Expect = 1e-16 Identities = 57/164 (34%), Positives = 86/164 (52%), Gaps = 8/164 (4%) Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 +G R+ V I + D ++ VF YTA V E + G V V+A D D+ +N ++ Sbjct: 207 NGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNKPVS 266 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 Y + + V + + FVI TG IT NK LDRET++ Y L V A ++ T Sbjct: 267 YFI------DQVTNPGEAFVIINTTGVITVNKPLDRETVAFYNLRVGAISTIHKAVFAT- 319 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 V+I++ D+NDN P F Y+ + E++ G +V +V A DAD Sbjct: 320 -VQITITDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDAD 362 Score = 78.6 bits (185), Expect = 7e-14 Identities = 53/142 (37%), Positives = 80/142 (56%), Gaps = 12/142 (8%) Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 L GT V V A D + N +I Y+L +D G F I+ +G I +N +DRE + + Sbjct: 67 LSGTGVLTVRAVDNE---NDQITYQLSGED---GRFKINSVTGEITSNVNIDREKLPGSN 120 Query: 655 L---KAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 L KA+A D G V V ++IED+ND+ PVF + + + EN+ +GTT + Sbjct: 121 LLEFKAIAYDAKGAGYDYRGDVPVRVQIEDVNDNTPVFINTPYSISVKENT-LGTTGFAV 179 Query: 710 RAHDPDEGPNAVVHYSIKGGDD 731 +A D D+G NA++ YSI GG++ Sbjct: 180 KATDADQGQNALIKYSITGGNE 201 Score = 78.6 bits (185), Expect = 7e-14 Identities = 53/134 (39%), Positives = 72/134 (53%), Gaps = 3/134 (2%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NR-LHYEITGGNTRGRFSITSQNGRGLI 423 F P Y ++AE G V T+TA D D N+ + Y I G + N G+I Sbjct: 230 FSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNKPVSYFIDQVTNPGEAFVII-NTTGVI 288 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 TV +PLD + Y L V A + ++ A VQI ITD N+ AP F N PY+ +V E++P Sbjct: 289 TVNKPLDRETVAFYNLRVGAISTIHKAVFATVQITITDINDNAPKFVNLPYSGTVPENSP 348 Query: 484 IGTTVLVVSATDSD 497 G TVL V+A D+D Sbjct: 349 TGLTVLRVTAQDAD 362 Score = 72.9 bits (171), Expect = 3e-12 Identities = 57/150 (38%), Positives = 74/150 (49%), Gaps = 20/150 (13%) Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT VL V A D++ N QITY LS E D +F IN TG IT+N +DRE + Sbjct: 69 GTGVLTVRAVDNE---NDQITYQLSGE---------DGRFKINSVTGEITSNVNIDREKL 116 Query: 545 SGYLL------TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 G L A+ G D V + + DVNDN PVF Y+ ++ E+ L GT Sbjct: 117 PGSNLLEFKAIAYDAKGAGYDYRGDVP-VRVQIEDVNDNTPVFINTPYSISVKENTL-GT 174 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEG 628 + V ATDAD G N I Y + + + G Sbjct: 175 TGFAVKATDADQGQNALIKYSITGGNEDLG 204 Score = 72.5 bits (170), Expect = 4e-12 Identities = 62/177 (35%), Positives = 85/177 (48%), Gaps = 10/177 (5%) Query: 131 SSTATIHVNI-IDDNDNYPQ-FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S TA V I ++D D+ P FS YT V E S T + + A D D+ N + Sbjct: 209 SRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAE--SSTKGFYVTTVTARDGDLSLNKPVS 266 Query: 189 YAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y I N F I + +G +++ K LD E V Y L + A + T Q I I Sbjct: 267 YFIDQVTNPGEAFVIINTTGVITVNKPLDRETVAFYNLRVGAISTIHKAVFATVQ--ITI 324 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE--GVNAELTYTMTDKDYT 302 D+NDNAP+F + +V EN P G +++RV A DAD ++ EL T T YT Sbjct: 325 TDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDADSVCTLHCELK-TSTSSVYT 380 Score = 71.3 bits (167), Expect = 1e-11 Identities = 83/316 (26%), Positives = 127/316 (40%), Gaps = 42/316 (13%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVL-VKATD-QASPVSDRLSSTATIHVNIIDDNDNY 147 F+I+ +G + + ++DREK+ +L KA A + V I D NDN Sbjct: 96 FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRGDVPVRVQIEDVNDNT 155 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F Y++SV E+ T +KATDAD G N +++SI + Sbjct: 156 PVFINTPYSISVKENTLGTTG---FAVKATDADQ-----------GQNALIKYSITGGNE 201 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 D+ G + SR+ T + I + DV+D F + V+ Sbjct: 202 DLG---------------------GVNGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVA 240 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E+ G+ + V A D D +N ++Y + D N I +G + + LDRE Sbjct: 241 ESSTKGFYVTTVTARDGDLSLNKPVSYFI---DQVTNPGEAFVIINTTGVITVNKPLDRE 297 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 T A Y L V A ++ AT F+ Y + E+ P G V+ Sbjct: 298 TVAFYNLRVGAI--STIHKAVFATVQITITDINDNAPKFVNLPYSGTVPENSPTGLTVLR 355 Query: 388 LTATDADEDNRLHYEI 403 +TA DAD LH E+ Sbjct: 356 VTAQDADSVCTLHCEL 371 Score = 64.9 bits (151), Expect = 9e-10 Identities = 62/196 (31%), Positives = 96/196 (48%), Gaps = 28/196 (14%) Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ---ERRYV 438 GT V+T+ A D +E++++ Y+++G + GRF I S G IT +D ++ Sbjct: 69 GTGVLTVRAVD-NENDQITYQLSGED--GRFKINSVTGE--ITSNVNIDREKLPGSNLLE 123 Query: 439 LTVSATDSGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 A D+ G R D V++ I D N+ PVF N PY+ SV E+ +GTT V A Sbjct: 124 FKAIAYDAKGAGYDYRGDVP-VRVQIEDVNDNTPVFINTPYSISVKENT-LGTTGFAVKA 181 Query: 494 TDSDVGINAQITYSLS-------------SEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 TD+D G NA I YS++ + +++ + D + + T K+ + Sbjct: 182 TDADQGQNALIKYSITGGNEDLGGVNGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAE 241 Query: 541 RETMSGYLLTVTARDG 556 T Y+ TVTARDG Sbjct: 242 SSTKGFYVTTVTARDG 257 Score = 52.8 bits (121), Expect = 4e-06 Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 15/142 (10%) Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRL 225 + ++A D + N I Y + G + + F I+S++G+++ +D E++ ++ Sbjct: 72 VLTVRAVDNE---NDQITYQLSGEDGR--FKINSVTGEITSNVNIDREKLPGSNLLEFKA 126 Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285 + G + + I DVNDN P F + + SV EN +G + V+A DAD Sbjct: 127 IAYDAKGAGYDYRGDVPVRVQIEDVNDNTPVFINTPYSISVKENT-LGTTGFAVKATDAD 185 Query: 286 EGVNAELTYTMTDKDYTGNVDL 307 +G NA + Y++T GN DL Sbjct: 186 QGQNALIKYSITG----GNEDL 203 Score = 47.6 bits (108), Expect = 1e-04 Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 1/53 (1%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 ++ + D ND++PVF Y SV+E + GTT +KATD D G+NA ++Y+I Sbjct: 145 RVQIEDVNDNTPVFINTPYSISVKEN-TLGTTGFAVKATDADQGQNALIKYSI 196 Score = 36.7 bits (81), Expect = 0.27 Identities = 17/42 (40%), Positives = 24/42 (57%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD 51 QI + D ND++P F Y +V E + +G TVL + A D D Sbjct: 321 QITITDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDAD 362 >SB_57964| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 134 Score = 95.9 bits (228), Expect = 4e-19 Identities = 49/132 (37%), Positives = 77/132 (58%), Gaps = 7/132 (5%) Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L+++A D D G+NA+I Y L I ++ +F +N TG IT + +D E S Y Sbjct: 8 LLLNARDKDEGVNAEIRYFLKDAIVSK-------RFSMNDTTGQITIKQAVDYEERSSYS 60 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 V A DGG L+ ++ V I+++DVNDN P F Y ++E+ +GT+V+QV A+D Sbjct: 61 FEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDL 120 Query: 609 DVGLNGRIHYEL 620 D LNG++ + + Sbjct: 121 DSSLNGKVLFSI 132 Score = 85.4 bits (202), Expect = 6e-16 Identities = 41/135 (30%), Positives = 76/135 (56%), Gaps = 2/135 (1%) Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 S ++P++ + A D D G N+ IRY + +FS++ +G +++ + +DYE+ SY Sbjct: 2 STLEDPLL--LNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTGQITIKQAVDYEERSSY 59 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283 + A DGG + ++ + I I DVNDN P F + + + ENV IG ++ +V A D Sbjct: 60 SFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASD 119 Query: 284 ADEGVNAELTYTMTD 298 D +N ++ +++ + Sbjct: 120 LDSSLNGKVLFSILE 134 Score = 63.7 bits (148), Expect = 2e-09 Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 6/125 (4%) Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 L A D DE + + Y + RFS+ G+ IT+ Q +D+++ Y V A+D Sbjct: 10 LNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTGQ--ITIKQAVDYEERSSYSFEVFASD 67 Query: 446 SGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G + ++ V+I I D N+ P F Y + E+ IGTTV V+A+D D +N + Sbjct: 68 GGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGK 127 Query: 504 ITYSL 508 + +S+ Sbjct: 128 VLFSI 132 Score = 62.1 bits (144), Expect = 6e-09 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 3/125 (2%) Query: 603 VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + A D D G+N I Y L KD F ++ +G I +A+D E +++ + A D Sbjct: 10 LNARDKDEGVNAEIRYFL--KDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASD 67 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 GG + + V I I D+ND+ P F + EN IGTT+ ++ A D D N Sbjct: 68 GGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGK 127 Query: 722 VHYSI 726 V +SI Sbjct: 128 VLFSI 132 Score = 56.8 bits (131), Expect = 2e-07 Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 4/116 (3%) Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 + A D DEGVNAE+ Y + D V +++ +G + +D E ++ Y V A Sbjct: 10 LNARDKDEGVNAEIRYFLKD----AIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFA 65 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 +DGG+ + +++ F+P +Y V+L E+ GT V +TA+D D Sbjct: 66 SDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLD 121 Score = 50.8 bits (116), Expect = 2e-05 Identities = 39/150 (26%), Positives = 73/150 (48%), Gaps = 24/150 (16%) Query: 43 LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102 L L A D+D G NAE+ Y ++ DA V F ++ +G + + Sbjct: 8 LLLNARDKDEGVNAEIRYFLK----------DAI---------VSKRFSMNDTTGQITIK 48 Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 ++D E+ + Y+ V A+D RL+ ++++ + IID NDN P F Y V + E+ Sbjct: 49 QAVDYEERSSYSFEVFASDGGEA---RLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVEN 105 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAII 192 +++ + ++ A+D D N + ++I+ Sbjct: 106 VAI--GTTVTQVTASDLDSSLNGKVLFSIL 133 Score = 39.5 bits (88), Expect = 0.038 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 8/87 (9%) Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + A D DEG NA + Y +K S FS+ G ++ +DYE R Y + Sbjct: 10 LNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTG----QITIKQAVDYEE-RSSYSFEVF 64 Query: 769 AA---SPPLWNDVRVEILVTDVNDNAP 792 A+ L V I + DVNDN P Sbjct: 65 ASDGGEARLTGSSSVRITIIDVNDNRP 91 Score = 38.7 bits (86), Expect = 0.066 Identities = 18/53 (33%), Positives = 30/53 (56%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 +I ++D ND+ P F +Y + E + GTTV + A+D D N +V ++I Sbjct: 80 RITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSI 132 >SB_32317| Best HMM Match : Cadherin (HMM E-Value=1.5e-28) Length = 331 Score = 86.2 bits (204), Expect = 3e-16 Identities = 66/200 (33%), Positives = 97/200 (48%), Gaps = 20/200 (10%) Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV-AQPLDFKQERR 436 D T V++T D + DN ++ N R S ++ G +I V A D + + + Sbjct: 26 DRKSATVRVSITVRDTN-DNSPQFQ--SQNYETRLSEAARPGSNVIQVSATDQDLEYKGK 82 Query: 437 YVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 + ++ D I + D N+ PVF + Y A V E++P GT VL V A+D Sbjct: 83 VIYNITDGDEN--------LIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDR 134 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G N +ITY L++ + D F IN TG IT ++DRE + ++LTV A D Sbjct: 135 DQGANGKITYKLTN-------GNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQ 187 Query: 557 GVPSLSDT-TDVEISVVDVN 575 G PS T +V I+V D N Sbjct: 188 GEPSSRKTFAEVVITVKDEN 207 Score = 82.2 bits (194), Expect = 5e-15 Identities = 48/129 (37%), Positives = 75/129 (58%), Gaps = 4/129 (3%) Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 +++D + I V DVNDN+PVF Q Y A+++E++ GT V +V A+D D G NG+I Y+ Sbjct: 86 NITDGDENLIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYK 145 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST---VIVHIK 676 L ++++ +F I+ +G I +DRE+V T L A D G P T V++ +K Sbjct: 146 LTNGNKDD-AFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVK 204 Query: 677 IEDINDSPP 685 E+I P Sbjct: 205 DENIEFLQP 213 Score = 79.4 bits (187), Expect = 4e-14 Identities = 47/142 (33%), Positives = 80/142 (56%), Gaps = 7/142 (4%) Query: 115 VLVKATDQASPVSDRLSSTATI---HVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPV 170 + V ATDQ ++ T ++ +DD NDN P F++ Y V E+ S T PV Sbjct: 68 IQVSATDQDLEYKGKVIYNITDGDENLIYVDDVNDNDPVFNQSKYAADVLEN-SPTGTPV 126 Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 + ++ A+D D GAN I Y + GN FSI++++G++++ +D E V ++ L ++A+ Sbjct: 127 L-RVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAE 185 Query: 231 DGGSP-SRSNTTQLLINIRDVN 251 D G P SR +++I ++D N Sbjct: 186 DQGEPSSRKTFAEVVITVKDEN 207 Score = 73.7 bits (173), Expect = 2e-12 Identities = 41/106 (38%), Positives = 58/106 (54%), Gaps = 4/106 (3%) Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 LI + DVNDN P F S + V EN P G ++RV A D D+G N ++TY +T+ G Sbjct: 94 LIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTN----G 149 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 N D +I+ +G + +G +DRE + L V A D G+P T Sbjct: 150 NKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKT 195 Score = 61.7 bits (143), Expect = 8e-09 Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 2/97 (2%) Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171 R+ + + ATDQA+P+SDR S+T + + + D NDN PQF + Y + E N + Sbjct: 10 RFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSN--V 67 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 ++ ATD D+ + Y I G+ + + D D Sbjct: 68 IQVSATDQDLEYKGKVIYNITDGDENLIYVDDVNDND 104 Score = 60.1 bits (139), Expect = 3e-08 Identities = 38/103 (36%), Positives = 55/103 (53%), Gaps = 7/103 (6%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F +Y ++ E+ P GTPV+ + A+D D+ + ++ Y++T GN FSI N G I Sbjct: 107 FNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSI--NNVTGEI 164 Query: 424 TVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDAN 463 TVA +D + +VLTV A D G R A V I + D N Sbjct: 165 TVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDEN 207 Score = 58.4 bits (135), Expect = 8e-08 Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 21/139 (15%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PVF +Y A V E + +GT VL + A+D+D G N ++ Y + D Sbjct: 95 IYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKD-- 152 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D F I+ +G + +DRE V + + V+A DQ P S + Sbjct: 153 -----------------DAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRK- 194 Query: 131 SSTATIHVNIIDDNDNYPQ 149 + A + + + D+N + Q Sbjct: 195 -TFAEVVITVKDENIEFLQ 212 Score = 58.0 bits (134), Expect = 1e-07 Identities = 35/91 (38%), Positives = 49/91 (53%), Gaps = 7/91 (7%) Query: 547 YLLTVTARDGGVPSLSD----TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 +LL +TA D P +SD T V I+V D NDN P F+ Q Y + E A G++V Q Sbjct: 11 FLLDITATDQATP-ISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQ 69 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVID 633 V ATD D+ G++ Y + D +E +D Sbjct: 70 VSATDQDLEYKGKVIYNI--TDGDENLIYVD 98 Score = 54.4 bits (125), Expect = 1e-06 Identities = 23/68 (33%), Positives = 37/68 (54%) Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 I ++D+ND+ PVF + ENSP GT + + A D D+G N + Y + G+ ++ Sbjct: 95 IYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDA 154 Query: 735 FSLETRQG 742 FS+ G Sbjct: 155 FSINNVTG 162 Score = 51.2 bits (117), Expect = 1e-05 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 5/73 (6%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---- 62 + I V D ND+SP F+ Q YE + E A G+ V+ + ATDQD+ +V Y I Sbjct: 32 VRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGD 91 Query: 63 -ELVTADTLNPED 74 L+ D +N D Sbjct: 92 ENLIYVDDVNDND 104 Score = 50.0 bits (114), Expect = 3e-05 Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 3/81 (3%) Query: 223 YRLVIRAQDGGSP---SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 + L I A D +P +S T ++ I +RD NDN+P+F + ++ +SE G ++++V Sbjct: 11 FLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQV 70 Query: 280 QAYDADEGVNAELTYTMTDKD 300 A D D ++ Y +TD D Sbjct: 71 SATDQDLEYKGKVIYNITDGD 91 Score = 49.6 bits (113), Expect = 4e-05 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 5/84 (5%) Query: 436 RYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 R++L ++ATD S +S T V I + D N+ +P F++ Y + E A G+ V+ Sbjct: 10 RFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQ 69 Query: 491 VSATDSDVGINAQITYSLSSEISN 514 VSATD D+ ++ Y+++ N Sbjct: 70 VSATDQDLEYKGKVIYNITDGDEN 93 Score = 41.9 bits (94), Expect = 0.007 Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 3/81 (3%) Query: 655 LKAVAIDGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 L A D TP +S+TV V I + D ND+ P F+S +SE + G+ + ++ A Sbjct: 13 LDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSA 72 Query: 712 HDPDEGPNAVVHYSIKGGDDS 732 D D V Y+I GD++ Sbjct: 73 TDQDLEYKGKVIYNITDGDEN 93 Score = 39.9 bits (89), Expect = 0.029 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 4/93 (4%) Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNAN 838 I V DVNDN PV + + ++ P G P RV A D D K+ Y++ +GN + Sbjct: 95 IYVDDVNDNDPVFNQSKYAADVLENS-PTGTPVLRVHASDRDQGANGKITYKLTNGNKDD 153 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +N TG +T++ ++ + V D Sbjct: 154 AFSINNVTGEITVAGVIDREAVHTFVLTVQAED 186 Score = 37.9 bits (84), Expect = 0.12 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Query: 331 KYQLLVTATDGGDP---PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 ++ L +TATD P +SAT F YE L+E PG+ V+ Sbjct: 10 RFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQ 69 Query: 388 LTATDADED--NRLHYEITGGN 407 ++ATD D + ++ Y IT G+ Sbjct: 70 VSATDQDLEYKGKVIYNITDGD 91 >SB_56860| Best HMM Match : Cadherin (HMM E-Value=4.4e-16) Length = 748 Score = 81.8 bits (193), Expect = 7e-15 Identities = 105/414 (25%), Positives = 167/414 (40%), Gaps = 35/414 (8%) Query: 372 EVELAEDEPPGTPVVTLTATDADE------DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 ++ + E+ P GT V LTA D D+ + +E+ + G F + + V Sbjct: 336 KLTVLENVPIGTEVGVLTANDGDDPWGTPASSNFSWELIS-TSDGHFKLIGSK----VVV 390 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 A+ LD + + + + + +D G + N P + SV EDA IG Sbjct: 391 AKSLDHESKSIHKIVIKCSDFGHPVGITTATFMVNVLNKDEPPKQITLNPTSVAEDAGIG 450 Query: 486 TTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRE 542 ++A D + I I S +S + + + T A + LD E Sbjct: 451 ARAAGLTALDEEGDTIVFSIAPSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYE 510 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y LTV A P IS+++VN+ P Q + ++ E+A+ GT + Sbjct: 511 ARDLYSLTVMANSSTGPVFKSFL---ISIINVNE-APSDVQLTGSHSVGENAMAGTIIGS 566 Query: 603 VGATDADVGLNG-RIHY--ELDPKDREEGSFVIDPASGVIRTNKAL---DRESVATHDLK 656 TD D + + HY + GS G + K + D E ++ Sbjct: 567 FMVTDPDNKVTQTQSHYCSAAAASAQSPGSSFFTVKGGAVLEVKGMPVIDYEKTRQLTIR 626 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY-ISENSPIGTTIGEIRAHDPD 715 D GTP S T I ++D+N++P S LT I ENSP GT +G + DP Sbjct: 627 VTCTDDGTPKLSITKDFVIIVKDVNEAPT---SITLTNKSIPENSPTGTLVGTLTCEDP- 682 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 E PN ++I G FS+ G+D + LDYE+ K ++V++A Sbjct: 683 ESPNDTCTFAIM-GPSGVPFSI----GADGKSFLVNGSLDYET-EKTIDVVVKA 730 Score = 73.7 bits (173), Expect = 2e-12 Identities = 120/454 (26%), Positives = 183/454 (40%), Gaps = 34/454 (7%) Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 + IRA D GSP + + +VND P +L + +V ENVPIG + + A D Sbjct: 300 VTIRATDDGSPQMWLEQTFKVKVLNVND--PPMNITLTKLTVLENVPIGTEVGVLTANDG 357 Query: 285 DE--GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D+ G A ++ + T + + V + LD E+++ +++++ +D G Sbjct: 358 DDPWGTPASSNFSW-ELISTSDGHFKLI----GSKVVVAKSLDHESKSIHKIVIKCSDFG 412 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE 402 P TAT V AED G LTA D + D + Sbjct: 413 HPVGITTATFMVNVLNKDEPPKQITLNPTSV--AEDAGIGARAAGLTALDEEGDTIVFSI 470 Query: 403 ITGGN-TRGRFSI--TS--QNGRGLITVAQ-----PLDFKQERRYVLTVSATDSGGRSDT 452 N T +F I TS NG+ A LD++ Y LTV A S G Sbjct: 471 APSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYEARDLYSLTVMANSSTGPVFK 530 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 + + I+I + N AP + SV E+A GT + TD D + ++ S+ Sbjct: 531 SFL-ISIINVNE-APSDVQLTGSHSVGENAMAGTIIGSFMVTDPDNKVTQTQSHYCSAAA 588 Query: 513 SNEAVAHHDQQFVINPQTGAITTNK---LLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 ++ A + F + + GA+ K ++D E + VT D G P LS T D I Sbjct: 589 AS-AQSPGSSFFTV--KGGAVLEVKGMPVIDYEKTRQLTIRVTCTDDGTPKLSITKDFVI 645 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 V DV NE L +I E++ GT V + D + N + + S Sbjct: 646 IVKDV--NEAPTSITLTNKSIPENSPTGTLVGTLTCEDPE-SPNDTCTFAIMGPSGVPFS 702 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D S ++ N +LD E+ T D+ A D G Sbjct: 703 IGADGKSFLV--NGSLDYETEKTIDVVVKATDRG 734 Score = 64.1 bits (149), Expect = 2e-09 Identities = 87/366 (23%), Positives = 144/366 (39%), Gaps = 20/366 (5%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 SLD E + + +++K +D PV +TAT VN+++ ++ Q + +V+ D I Sbjct: 393 SLDHESKSIHKIVIKCSDFGHPVG---ITTATFMVNVLNKDEPPKQITLNPTSVAEDAGI 449 Query: 164 SVTDNPVIAKIKATDADVGA-----NSAIRYAIIGGNT-QMQFSIDSLSGDVSLVKTLDY 217 + A + D V + NS + IG + ++ + + D+ + LDY Sbjct: 450 GARAAGLTALDEEGDTIVFSIAPSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDY 509 Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 E Y L + A P + LI+I +VN+ AP SV EN G I Sbjct: 510 EARDLYSLTVMANSSTGPVFKS---FLISIINVNE-APSDVQLTGSHSVGENAMAGTIIG 565 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY-TSGQ--LDRETQAKYQL 334 D D V ++ + + + G V G +D E + + Sbjct: 566 SFMVTDPDNKVTQTQSHYCSAAAASAQSPGSSFFTVKGGAVLEVKGMPVIDYEKTRQLTI 625 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 VT TD G P S T + E+ P GT V TLT D + Sbjct: 626 RVTCTDDGTPKLSITKDFVIIVKDVNEAPTSITLTNKSIP--ENSPTGTLVGTLTCEDPE 683 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 N G + FSI + +G+ + V LD++ E+ + V ATD GG + Sbjct: 684 SPNDTCTFAIMGPSGVPFSIGA-DGKSFL-VNGSLDYETEKTIDVVVKATDRGGLYKEEI 741 Query: 455 VQINIT 460 + ++++ Sbjct: 742 LTVSVS 747 Score = 59.7 bits (138), Expect = 3e-08 Identities = 92/403 (22%), Positives = 160/403 (39%), Gaps = 39/403 (9%) Query: 115 VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174 V ++ATD SP ++ T V +++ ND P + ++V E++ + + + Sbjct: 300 VTIRATDDGSP---QMWLEQTFKVKVLNVND--PPMNITLTKLTVLENVPIGTE--VGVL 352 Query: 175 KATDAD----VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 A D D A+S + +I + F + + V + K+LD+E +++VI+ Sbjct: 353 TANDGDDPWGTPASSNFSWELIS-TSDGHFKL--IGSKVVVAKSLDHESKSIHKIVIKCS 409 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 D G P T ++N+ +N + P +L SV+E+ IG + A D +EG Sbjct: 410 DFGHPVGITTATFMVNV--LNKDEPPKQITLNPTSVAEDAGIGARAAGLTALD-EEGDTI 466 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYT-------SGQLDRETQAKYQLLVTATDGGD 343 + +D ++ T +G T G+LD E + Y L V A Sbjct: 467 VFSIAPSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYEARDLYSLTVMANSSTG 526 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLH 400 P + + G + V E+ GT + + TD D + H Sbjct: 527 PVFKSFLISIINVNEAPSDVQ--LTGSHSV--GENAMAGTIIGSFMVTDPDNKVTQTQSH 582 Query: 401 Y---EITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSG--GRSDTAM 454 Y + G T + G L P +D+++ R+ + V+ TD G S T Sbjct: 583 YCSAAAASAQSPGSSFFTVKGGAVLEVKGMPVIDYEKTRQLTIRVTCTDDGTPKLSITKD 642 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 I + D N AP S+ E++P GT V ++ D + Sbjct: 643 FVIIVKDVNE-APTSITLT-NKSIPENSPTGTLVGTLTCEDPE 683 Score = 56.8 bits (131), Expect = 2e-07 Identities = 66/251 (26%), Positives = 102/251 (40%), Gaps = 24/251 (9%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L+ + LD E Y++ V A PV + ++II+ N+ P + T + S Sbjct: 501 LMVKGKLDYEARDLYSLTVMANSSTGPVFK------SFLISIINVNEA-PSDVQLTGSHS 553 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL----SGDVSLVK- 213 V E+ +I TD D + Q S G V VK Sbjct: 554 VGENAMA--GTIIGSFMVTDPDNKVTQTQSHYCSAAAASAQSPGSSFFTVKGGAVLEVKG 611 Query: 214 --TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 +DYE+ R + + D G+P S T +I ++DVN+ AP T L +S+ EN P Sbjct: 612 MPVIDYEKTRQLTIRVTCTDDGTPKLSITKDFVIIVKDVNE-APTSIT-LTNKSIPENSP 669 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 G ++V + E N T+ + G +P +I +G LD ET+ Sbjct: 670 TG-TLVGTLTCEDPESPNDTCTFAI-----MGPSGVPFSIGADGKSFLVNGSLDYETEKT 723 Query: 332 YQLLVTATDGG 342 ++V ATD G Sbjct: 724 IDVVVKATDRG 734 Score = 56.4 bits (130), Expect = 3e-07 Identities = 62/248 (25%), Positives = 107/248 (43%), Gaps = 23/248 (9%) Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 +T+ A D G P + ++ V++VND P L ++E+ +GT V + A D Sbjct: 300 VTIRATDDGSPQMWLEQTFKVKVLNVND--PPMNITLTKLTVLENVPIGTEVGVLTANDG 357 Query: 609 D--VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D G ++ + +G F + + V+ K+LD ES + H + D G P Sbjct: 358 DDPWGTPASSNFSWELISTSDGHFKLIGSKVVVA--KSLDHESKSIHKIVIKCSDFGHPV 415 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +T + + +N P + ++E++ IG + A D +EG V +SI Sbjct: 416 GITTATFMVNV--LNKDEPPKQITLNPTSVAEDAGIGARAAGLTALD-EEGDTIV--FSI 470 Query: 727 KGGDDS---------NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--PLW 775 D+S S L +Q + A+L+ LDYE+ R Y L + A S P++ Sbjct: 471 APSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYEA-RDLYSLTVMANSSTGPVF 529 Query: 776 NDVRVEIL 783 + I+ Sbjct: 530 KSFLISII 537 >SB_10800| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 943 Score = 76.2 bits (179), Expect = 4e-13 Identities = 72/287 (25%), Positives = 124/287 (43%), Gaps = 16/287 (5%) Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF---ENAPYTASVFED 481 +A+ L+ + + LT+ A D+ R T V+ +I + N + P F E+ PY +V E+ Sbjct: 26 IARALNSDENKFCELTIIAKDAEKRVTTTRVRFDIINMNKHRPQFNKPESEPYICAVTEN 85 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA-ITTNKLLD 540 + + ++ TD D G +I E++ + +F +N + K D Sbjct: 86 TRVVRILPKINVTDQDRGEAGKIK---RIEVAESGIPF---KFNVNDDGSVEVVALKDFD 139 Query: 541 RETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 E SGYL + A DGG PS S V+ +VDVN+ P F+ A ++E Sbjct: 140 AEKESGYLFDIKAFDGGDPSKTSKPVQVDCRIVDVNEFPPTFESNNVVA-VVERGKTYKK 198 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + Q+ ATD D+G + + + + + + GV+ +K L ++ + A Sbjct: 199 ILQLTATDKDIGKENGVVCKYVVRTADVPFKITN--DGVLYLDKPLGSDAPEYCAFEVAA 256 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 +D G V V + I+D P + D L +S +G I Sbjct: 257 VDCGGKISVENVNVRVDIKD--SCKPGYNMDQLLGKVSIPQCVGKAI 301 Score = 56.4 bits (130), Expect = 3e-07 Identities = 57/198 (28%), Positives = 94/198 (47%), Gaps = 17/198 (8%) Query: 97 GALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE--- 152 G + RA + D K T++ K ++ R+++T + +II+ N + PQF++ Sbjct: 23 GKKIARALNSDENKFCELTIIAKDAEK------RVTTTR-VRFDIINMNKHRPQFNKPES 75 Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI-RYAIIGGNTQMQFSI-DSLSGDVS 210 + Y +V E+ V ++ KI TD D G I R + +F++ D S +V Sbjct: 76 EPYICAVTENTRVVR--ILPKINVTDQDRGEAGKIKRIEVAESGIPFKFNVNDDGSVEVV 133 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 +K D E+ Y I+A DGG PS+ S Q+ I DVN+ P F ++ +V E Sbjct: 134 ALKDFDAEKESGYLFDIKAFDGGDPSKTSKPVQVDCRIVDVNEFPPTFESNNV-VAVVER 192 Query: 270 VPIGYSIVRVQAYDADEG 287 I+++ A D D G Sbjct: 193 GKTYKKILQLTATDKDIG 210 Score = 43.2 bits (97), Expect = 0.003 Identities = 53/270 (19%), Positives = 106/270 (39%), Gaps = 14/270 (5%) Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++S + + L+ ++ + L I A+D + R TT++ +I ++N + P+F + Sbjct: 19 AVSEGKKIARALNSDENKFCELTIIAKD--AEKRVTTTRVRFDIINMNKHRPQFNKPESE 76 Query: 264 E---SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI-DPRSGWVY 319 +V+EN + + ++ D D G ++ + + + D S V Sbjct: 77 PYICAVTENTRVVRILPKINVTDQDRGEAGKIKRIEVAES---GIPFKFNVNDDGSVEVV 133 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 D E ++ Y + A DGGDP +++ V + E Sbjct: 134 ALKDFDAEKESGYLFDIKAFDGGDPSKTSKPVQVDCRIVDVNEFPPTFESNNVVAVVERG 193 Query: 380 PPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 ++ LTATD D ++N + + F IT+ G++ + +PL Sbjct: 194 KTYKKILQLTATDKDIGKENGVVCKYVVRTADVPFKITND---GVLYLDKPLGSDAPEYC 250 Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAP 467 V+A D GG+ V + + ++ P Sbjct: 251 AFEVAAVDCGGKISVENVNVRVDIKDSCKP 280 Score = 35.1 bits (77), Expect = 0.82 Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 ++D N+ P FE A V G + +L L ATD+DIGK V + TAD Sbjct: 171 IVDVNEFPPTFESNNVVAVVERGKTY-KKILQLTATDKDIGKENGVVCKYVVRTAD 225 >SB_45116| Best HMM Match : EGF (HMM E-Value=0) Length = 2023 Score = 74.5 bits (175), Expect = 1e-12 Identities = 82/292 (28%), Positives = 118/292 (40%), Gaps = 36/292 (12%) Query: 1292 HKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 H ID+ VAD G L ++ CSS PC NGA CSDL + Y C C G G+ C Sbjct: 1276 HPNIDMEKGVADQGNLIADIDE---CSSNPCLNGATCSDLLNNYTCTCASGFQGERCEQK 1332 Query: 1352 TGPPWRFGGDGMLSF----NPLLRPIQLPWLNALSIRTRQRDAFVMS---------IQL- 1397 T F G +F PL++ + S+ ++ +MS IQ+ Sbjct: 1333 TSCQLAFYGRSTSNFAAVTMPLIKFEEFTICAWYSLAQEWQENVIMSYVTSNNRSQIQVA 1392 Query: 1398 --KSGLLHYSYNGETMYLPMAT--LSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLAN 1453 K G L N T+ +P++ LS WH + ++W TD TV YG +T + Sbjct: 1393 IRKDGKLELMVNWNTVTVPVSANFLSIIGWHFLCVQW-KTDGKATV-YGDKTSFGDDTFD 1450 Query: 1454 KIQGQYI---GKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDG 1510 K++ I GK+++G D F G + V I S L+ + Sbjct: 1451 KLKNLGIVGGGKVVLGASQRCLEGCFDDRLTFHGNVSQVNIW--NSKLSSGDIELVFVGS 1508 Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARC 1562 C S ++ P V W + + G VG C +C GP GA C Sbjct: 1509 CLSYG----AVDSP----VLGWKTIQASPLNGAVGGVCPVSCPFGPTGALSC 1552 Score = 69.7 bits (163), Expect = 3e-11 Identities = 63/209 (30%), Positives = 77/209 (36%), Gaps = 29/209 (13%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQT 1567 C+ +C + C CV D TCTCEAG G C ++ C+ GPC D+ Sbjct: 160 CEEIKECTSAPCQNGGSCVDRRDGYTCTCEAGYNGINCEIEINECDSGPCNNGGTCTDRV 219 Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNK-ENG- 1624 GY C C GYT T C E +EC G C D+ GY+ C NG Sbjct: 220 -NGYECVCNAGYTGTR--C-EIDIDECASNPCINGGTC----TDMVNGYNCTCPPGYNGT 271 Query: 1625 KC-----HCKENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 C C N GT L C C G ++CE +C P V G C Sbjct: 272 TCEIDINECASNPCLNGGTCNDLVNGYNCNC-PPGYNGTTCEIDINECASNPCVNGGTCA 330 Query: 1676 ACANAYAEVTPNSGCEVVYDGCPRSFAGG 1704 N + N C Y G A G Sbjct: 331 DLVNGF-----NCTCPPGYKGTKCEIATG 354 Score = 56.0 bits (129), Expect = 4e-07 Identities = 56/212 (26%), Positives = 78/212 (36%), Gaps = 39/212 (18%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS---------ACELGPCGAARCVPDQ 1566 +C + C C +S +CTC +G G QC + A ++ C + C+ Sbjct: 1024 ECDSNPCANGGTCADQVNSFSCTCVSGYTGLQCKTGTVLRYNEKAVDINECASNPCLNGG 1083 Query: 1567 T----PKGYSCACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620 T GY+C C+PGY TT E +C G G C D+ G++ C Sbjct: 1084 TCNDLVNGYNCKCQPGYNGTTCEIDINECASNQCVNG-------GTCT-DLVNGFNCTCP 1135 Query: 1621 K-ENG-KC-----HCKENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGV 1669 NG KC C+ N GT C C +G CE +C P V Sbjct: 1136 PGYNGTKCEININECENNPCVNGGTCADQVNSFSCTC-VSGYTGLKCETDINECASNPCV 1194 Query: 1670 IGRACDACANAYAEVTP----NSGCEVVYDGC 1697 G C N + P + CE+ D C Sbjct: 1195 NGGTCTDLVNGFHCTCPPGYNGTKCEIDIDEC 1226 Score = 51.6 bits (118), Expect = 9e-06 Identities = 51/177 (28%), Positives = 63/177 (35%), Gaps = 28/177 (15%) Query: 1534 SSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESG 1590 +S C C AG G C + C PC CV + GY+C CE GY C E Sbjct: 146 TSRCRCVAGYTGEHCEEIKECTSAPCQNGGSCVDRR--DGYTCTCEAGY--NGINC-EIE 200 Query: 1591 KEECPGGWWGGSACGPCACDVTRGYHPHCNK--ENGKC-----HCKENHYKPEGTAECL- 1642 EC G G C D GY CN +C C N GT + Sbjct: 201 INECDSGPCNNG--GTCT-DRVNGYECVCNAGYTGTRCEIDIDECASNPCINGGTCTDMV 257 Query: 1643 ---PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDG 1696 C C G ++CE +C P + G C+ N Y N C Y+G Sbjct: 258 NGYNCTC-PPGYNGTTCEIDINECASNPCLNGGTCNDLVNGY-----NCNCPPGYNG 308 Score = 46.0 bits (104), Expect = 4e-04 Identities = 17/37 (45%), Positives = 22/37 (59%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E+ C+SAPC NG C D D Y C C+ G+ G +C Sbjct: 161 EEIKECTSAPCQNGGSCVDRRDGYTCTCEAGYNGINC 197 Score = 45.2 bits (102), Expect = 8e-04 Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 2/50 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 NGT C + C+S PC NG C+DL + + C C G+ G C +TG Sbjct: 307 NGTT--CEIDINECASNPCVNGGTCADLVNGFNCTCPPGYKGTKCEIATG 354 Score = 44.8 bits (101), Expect = 0.001 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 NGT C + C+S PC NG C+DL + Y C+C G+ G C Sbjct: 269 NGTT--CEIDINECASNPCLNGGTCNDLVNGYNCNCPPGYNGTTC 311 Score = 43.6 bits (98), Expect = 0.002 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 NGT C + C S PC NG C+D +++ C C G+TG C T Sbjct: 1014 NGTK--CEIDINECDSNPCANGGTCADQVNSFSCTCVSGYTGLQCKTGT 1060 Score = 43.2 bits (97), Expect = 0.003 Identities = 15/34 (44%), Positives = 21/34 (61%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C+S PC NG C+DL + Y C C+ G+ G C Sbjct: 1072 NECASNPCLNGGTCNDLVNGYNCKCQPGYNGTTC 1105 Score = 42.3 bits (95), Expect = 0.005 Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C S PC NG C+D + Y C C G+TG C Sbjct: 197 CEIEINECDSGPCNNGGTCTDRVNGYECVCNAGYTGTRC 235 Score = 41.9 bits (94), Expect = 0.007 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NG C+DL + + C C G+ G C Sbjct: 1181 CETDINECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKC 1219 Score = 41.5 bits (93), Expect = 0.009 Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC NG C+D+ + Y C C G+ G C Sbjct: 235 CEIDIDECASNPCINGGTCTDMVNGYNCTCPPGYNGTTC 273 Score = 41.5 bits (93), Expect = 0.009 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 NGT C + C + PC NG C+D +++ C C G+TG C Sbjct: 1139 NGTK--CEININECENNPCVNGGTCADQVNSFSCTCVSGYTGLKC 1181 Score = 40.7 bits (91), Expect = 0.016 Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C+S PC NG C+DL + + C C G+ G C Sbjct: 985 NECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKC 1018 Score = 39.1 bits (87), Expect = 0.050 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 NGT C + C+S C NG C+DL + + C C G+ G C Sbjct: 1101 NGTT--CEIDINECASNQCVNGGTCTDLVNGFNCTCPPGYNGTKC 1143 Score = 39.1 bits (87), Expect = 0.050 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 NGT C C+S PC NG C++L + + C C G+ G C Sbjct: 1215 NGTK--CEIDIDECASNPCINGGTCTELVNGFKCTCVPGYNGTRC 1257 Score = 38.7 bits (86), Expect = 0.066 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 10/64 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC C G+ G+NCE + + D C +G C R G C +A YT Sbjct: 184 YTCTCEAGYNGINCEIEINEC------DSGPCNNGGTCTDRVNG----YECVCNAGYTGT 233 Query: 1102 VCEL 1105 CE+ Sbjct: 234 RCEI 237 Score = 38.7 bits (86), Expect = 0.066 Identities = 40/168 (23%), Positives = 58/168 (34%), Gaps = 21/168 (12%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C C + CTC G G +C + C PC C + G+ Sbjct: 1187 ECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKCEIDIDECASNPCINGGTCT--ELVNGF 1244 Query: 1572 SCACEPGYTLTTSGCIESGK--EECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 C C PGY T + + ++CP + G D+ +G N C Sbjct: 1245 KCTCVPGYNGTRCEIVLRPRPPKDCPSRFEGHP-----NIDMEKGVADQGNLIADIDECS 1299 Query: 1630 ENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRA 1673 N T L C C A+G + CE T C+ GR+ Sbjct: 1300 SNPCLNGATCSDLLNNYTCTC-ASGFQGERCEQKTS---CQLAFYGRS 1343 Score = 37.9 bits (84), Expect = 0.12 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 11/62 (17%) Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103 C+C G+TG +CE I S C++G CV RR+G C+ +A Y C Sbjct: 149 CRCVAGYTGEHCEEIKECTSAP-------CQNGGSCVDRRDG----YTCTCEAGYNGINC 197 Query: 1104 EL 1105 E+ Sbjct: 198 EI 199 Score = 36.7 bits (81), Expect = 0.27 Identities = 40/163 (24%), Positives = 50/163 (30%), Gaps = 14/163 (8%) Query: 1549 VSACELGPCGAARCVPDQTPKGYSCACEPGY--TLTTSGCIESGKEECPGGWWGGSACGP 1606 ++ C PC D G+ C C PGY T E C G Sbjct: 984 INECASNPCVNGGTCTDLV-NGFHCTCPPGYNGTKCEIDINECDSNPCANGGTCADQVNS 1042 Query: 1607 CACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCR 1666 +C GY K E K EC C G+ N C C+ Sbjct: 1043 FSCTCVSGYTGLQCKTGTVLRYNE---KAVDINECASNPCLNGGTCNDLVNGY--NCKCQ 1097 Query: 1667 PGVIGRACDACANAYA-EVTPNSG-CEVVYDG----CPRSFAG 1703 PG G C+ N A N G C + +G CP + G Sbjct: 1098 PGYNGTTCEIDINECASNQCVNGGTCTDLVNGFNCTCPPGYNG 1140 Score = 35.1 bits (77), Expect = 0.82 Identities = 13/35 (37%), Positives = 20/35 (57%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073 V SF+C C G+TG+ CET + + + +G C Sbjct: 1165 VNSFSCTCVSGYTGLKCETDINECASNPCVNGGTC 1199 Score = 33.5 bits (73), Expect = 2.5 Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQG--CSIDA 1096 V SF+C C G+TG+ C+T E D + C S + C+ L G C Sbjct: 1040 VNSFSCTCVSGYTGLQCKTGTVLRYNEKAVDINECAS-NPCLNGGTCNDLVNGYNCKCQP 1098 Query: 1097 AYTTAVCEL 1105 Y CE+ Sbjct: 1099 GYNGTTCEI 1107 Score = 32.3 bits (70), Expect = 5.8 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V F C CP G+ G CE + + CE + C +G C + + C+ + Y Sbjct: 1127 VNGFNCTCPPGYNGTKCEININE--CE----NNPCVNGGTCADQ----VNSFSCTCVSGY 1176 Query: 1099 TTAVCE 1104 T CE Sbjct: 1177 TGLKCE 1182 >SB_54100| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3287 Score = 74.1 bits (174), Expect = 1e-12 Identities = 81/339 (23%), Positives = 128/339 (37%), Gaps = 46/339 (13%) Query: 1281 FVGCISDFYIDHKFIDLNSYVADNGTLA----GCPEKRSRCSSAPCYNGAECSDLWDTYI 1336 F GC+ D +++ + S V + + GC K + C + C NG C W + Sbjct: 1427 FNGCVRDIFVNSVEQNFGSAVRSSSSFTLPKPGC-RKETNCHAESCANGGTCVATWTGFQ 1485 Query: 1337 CDCKEGHTGKDCADSTGPP----------------WRFGGDGMLSFNPLLRPIQLPWLNA 1380 C C G C + T WRFG G L R I L L Sbjct: 1486 CRCLAEFNGTRCENGTATTFLANTSSIQLGLNTTEWRFGQSGSLRVRTS-RAIGL--LLY 1542 Query: 1381 LSIRTRQRDAFVMSIQLKSGLLHYSYN---GETMYLPMATLSDGAWHRIEIKWLGTDISV 1437 + + + + L SG + + + G + T++DG WH I + + Sbjct: 1543 AGWKPSGPNTEYLMVDLVSGKVRLTADLGSGPGSVINPMTVNDGDWHHITWSRQYKRLIL 1602 Query: 1438 TVD---YGLRTVLMPMLANKIQGQYIGKILIGGLD--TTAGLLASDVGFFEGCIQD---- 1488 +VD + T + + + I + IGG ++ S + F+GC++D Sbjct: 1603 SVDDVTMEMSTQGEQSVLDVADSEII-YVHIGGFPYLKSSATGLSTITSFQGCLKDLTFH 1661 Query: 1489 ---VRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG 1545 V T S ++ NV GC S C + C YS C + + CTC +G G Sbjct: 1662 YRYVHFLTPFSQQGLASILRNVTTGCHSIGPCSSNPCQGYSTCENAGGAYNCTCLSGWTG 1721 Query: 1546 PQC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 +C + C + C A CV + G+ C C G+T Sbjct: 1722 DKCDVRIPDCIIANCSNGATCVNES--NGFRCQCAVGFT 1758 Score = 72.1 bits (169), Expect = 6e-12 Identities = 86/314 (27%), Positives = 123/314 (39%), Gaps = 46/314 (14%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 F C C G+TG+ C + + + S C +G C G C+ YT + Sbjct: 967 FICDCKAGYTGLACTINIDECA------SSPCFNGGSCRDDVNG----YTCTCAPGYTGS 1016 Query: 1102 VCE-LRARSFPVSSFLTFPGLKRR---HRIHLKLKFATQTTSGLLLYNG--RYNERHDFL 1155 CE L SF S++ + R R ++ F T + GLLLY G R E D + Sbjct: 1017 RCEMLDEVSFRRGSYMPVYWYRDRPLPARARVEFLFRTSLSDGLLLYQGADRSLEHPDHV 1076 Query: 1156 ALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDC 1215 ALEL+ RG LR S + G T+ ++ D ++H V + N T+ + Sbjct: 1077 ALELL-----RG---SLRLSLNTGFDTQVDTIGRDLNDSTYHQVTLVLENNRATVEVS-- 1126 Query: 1216 DKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQ 1275 G+ D G K + V A + T L G Q G P I Sbjct: 1127 ------GGSCDAGCKGSVTTQLSAVF-AYSGLAT--------LGGLAQTG--PVIRDQI- 1168 Query: 1276 VKNKDFVGCISDFYIDHKFIDLNSYVADN-GTLAGCPEKRSRCSSAPCYNGAECSDLWDT 1334 + +FVGCI DF ++ L ++ GC + C + C NG C D+W Sbjct: 1169 ATDGNFVGCIKDFKLNLISDYLRDFIPHAVHVTPGC-ARTDVCKNHKCTNGGACVDMWSE 1227 Query: 1335 YICDCKEGHTGKDC 1348 Y C C G G C Sbjct: 1228 YRCQCPTGFAGTFC 1241 Score = 60.5 bits (140), Expect = 2e-08 Identities = 65/266 (24%), Positives = 98/266 (36%), Gaps = 31/266 (11%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369 C C+S+PC+NG C D + Y C C G+TG C +R G M + Sbjct: 980 CTINIDECASSPCFNGGSCRDDVNGYTCTCAPGYTGSRCEMLDEVSFR-RGSYMPVYWYR 1038 Query: 1370 LRPIQLPWLNALSIRTRQRDAFVM--------------SIQLKSGLLHYSYNG--ETMYL 1413 RP+ RT D ++ +++L G L S N +T Sbjct: 1039 DRPLPARARVEFLFRTSLSDGLLLYQGADRSLEHPDHVALELLRGSLRLSLNTGFDTQVD 1098 Query: 1414 PMA-TLSDGAWHRIEIKWLGTDISVTV-----DYGLRTVLMPMLANKIQGQYIGKILIGG 1467 + L+D +H++ + +V V D G + + L+ Y G +GG Sbjct: 1099 TIGRDLNDSTYHQVTLVLENNRATVEVSGGSCDAGCKGSVTTQLSAVF--AYSGLATLGG 1156 Query: 1468 LDTTAGLLASDV---GFFEGCIQDVRIGTAQSLLNRPTVRE--NVRDGCQSRADCMLSIC 1522 L T ++ + G F GCI+D ++ L R + +V GC C C Sbjct: 1157 LAQTGPVIRDQIATDGNFVGCIKDFKLNLISDYL-RDFIPHAVHVTPGCARTDVCKNHKC 1215 Query: 1523 PPYSKCVTSWDSSTCTCEAGRVGPQC 1548 CV W C C G G C Sbjct: 1216 TNGGACVDMWSEYRCQCPTGFAGTFC 1241 Score = 56.4 bits (130), Expect = 3e-07 Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 11/166 (6%) Query: 1392 VMSIQLKSGLLHYSYN----GETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVL 1447 V+ + L++G LH +Y T LS+G WHR+EI I++ V+ + + Sbjct: 1334 VLGLALRNGRLHAAYVMGFFQSTSVEIGRDLSNGNWHRVEISVTFGYITIKVNSDVTILR 1393 Query: 1448 MPMLANKIQGQ-YIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQ----SLLNRPT 1502 P +Q + Y+G +L + L S F GC++D+ + + + S + + Sbjct: 1394 PPSTVPNLQTKVYMGNLLSSMTELNVELSRSIT--FNGCVRDIFVNSVEQNFGSAVRSSS 1451 Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548 + GC+ +C C CV +W C C A G +C Sbjct: 1452 SFTLPKPGCRKETNCHAESCANGGTCVATWTGFQCRCLAEFNGTRC 1497 Score = 54.8 bits (126), Expect = 9e-07 Identities = 51/183 (27%), Positives = 64/183 (34%), Gaps = 17/183 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C + D C C + CV+S TC C G G C + C PC D+ Sbjct: 2163 CNTLIDFCYSDPCAYGATCVSSLADYTCACVPGYTGRNCTTNIDDCLSAPCKNGATCEDK 2222 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGYHPHCNKE 1622 GY C C G+ T C E+ E P G+ C AC GY N Sbjct: 2223 V-NGYLCKCPDGFHST--NCSENINECDPNPCLNGATCLDKIADYACVCPSGY-SGINCS 2278 Query: 1623 NGKCHCKENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678 C+ N + GT L C C A G +C C RP G C+ Sbjct: 2279 VNVNDCRTNPCENGGTCIDLIGGYACTC-APGFTGVNCSVNIDDCASRPCKNGATCNDGV 2337 Query: 1679 NAY 1681 N+Y Sbjct: 2338 NSY 2340 Score = 53.6 bits (123), Expect = 2e-06 Identities = 48/177 (27%), Positives = 60/177 (33%), Gaps = 12/177 (6%) Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACE 1576 S C + C+ +S TC C G G C V+ C PC D GYSCAC Sbjct: 672 SPCSEHGACIDGVNSYTCACNLGYTGSTCNVTVNDCISNPCIHGATCHDGL-LGYSCACA 730 Query: 1577 PGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKC---HCKE 1630 G+T + C C GY + C+ +C C Sbjct: 731 VGFTGINCEININDCASNPCAAYQRCIDRIDSYTCACPLGYTGNACDVNIDECASQPCLN 790 Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPN 1687 N +G C C AG E CE T +C P G C N + V PN Sbjct: 791 NGTCQDGRGN-FSCVC-PAGFEGLRCENQTNECASSPCFNGGTCHDLLNRFECVCPN 845 Score = 49.2 bits (112), Expect = 5e-05 Identities = 50/188 (26%), Positives = 64/188 (34%), Gaps = 26/188 (13%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG- 1570 DC + C Y +C+ DS TC C G G C + C PC C Q +G Sbjct: 744 DCASNPCAAYQRCIDRIDSYTCACPLGYTGNACDVNIDECASQPCLNNGTC---QDGRGN 800 Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 +SC C G+ C E+ EC + G C D+ + C C+ Sbjct: 801 FSCVCPAGF--EGLRC-ENQTNECASSPCFNGGTCH----DLLNRFECVCPNGFLGRQCE 853 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689 N ECL C G+ QC C G G AC Y Sbjct: 854 AN------VVECLSDPCLNNGTCVEKIGVVGYQCVCPDGFAGDFSCACPVGYT----GKL 903 Query: 1690 CEVVYDGC 1697 CE+ D C Sbjct: 904 CEIDIDDC 911 Score = 49.2 bits (112), Expect = 5e-05 Identities = 48/176 (27%), Positives = 60/176 (34%), Gaps = 14/176 (7%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC + C + CV + +C C AG G C + C PC D+ Y Sbjct: 2601 DCATNPCGNGATCVDEINKYSCLCPAGFSGGNCQTNIDECASRPCANVGSCIDRI-NSYE 2659 Query: 1573 CACEPGYTLTTS--GCIESGKEEC-PGGWWGGSACG-PCACDVTRGY-HPHCNKENGKCH 1627 C C PGYT E + C GG G CAC V GY +C+ E +C Sbjct: 2660 CTCVPGYTGRNCQVDIDECESKPCVNGGTCIDRVAGYSCACAV--GYTDQNCSVEIDECA 2717 Query: 1628 CKE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 N C C G +CE +C P G C N Y Sbjct: 2718 SNPCLNGATCTDRLGGYACSC-IPGFTGKNCETDLDECLSNPCGNGATCRHLVNNY 2772 Score = 48.8 bits (111), Expect = 6e-05 Identities = 50/200 (25%), Positives = 74/200 (37%), Gaps = 23/200 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C C+ + TC C+ G +G +C ++ C PC A+C Q G+ Sbjct: 589 ECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRCHAFINKCLFNPCKNGAKCQTLQ-DGGH 647 Query: 1572 SCACEPGY--TLTTSGCIESGKEECPGGWWGGSACG----PCACDVTRGY-HPHCNKENG 1624 C CE G+ +L E + + P G G CAC++ GY CN Sbjct: 648 RCLCEKGFKGSLCEVNVNECNETQSPCSEHGACIDGVNSYTCACNL--GYTGSTCNVTVN 705 Query: 1625 KC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 C C +G C C A G +CE C P + C ++Y Sbjct: 706 DCISNPCIHGATCHDGLLG-YSCAC-AVGFTGINCEININDCASNPCAAYQRCIDRIDSY 763 Query: 1682 AEVTP----NSGCEVVYDGC 1697 P + C+V D C Sbjct: 764 TCACPLGYTGNACDVNIDEC 783 Score = 48.0 bits (109), Expect = 1e-04 Identities = 47/163 (28%), Positives = 62/163 (38%), Gaps = 20/163 (12%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC S C + CV + +CTC G C + C PC A CV D K Y Sbjct: 2525 DCATSPCRNGATCVDGINKYSCTCPIGFTDQTCSTNIDDCATNPCRNGATCV-DGINK-Y 2582 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631 SC C G+T T C + ++C G A C ++ + Y C +C+ N Sbjct: 2583 SCTCPIGFTDQT--C-STNIDDCATNPCGNGA--TCVDEINK-YSCLCPAGFSGGNCQTN 2636 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 EC C GS + +C C PG GR C Sbjct: 2637 ------IDECASRPCANVGSCIDRINSY--ECTCVPGYTGRNC 2671 Score = 47.6 bits (108), Expect = 1e-04 Identities = 45/185 (24%), Positives = 68/185 (36%), Gaps = 33/185 (17%) Query: 1509 DGCQSRA-DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563 D C R DC+++ C + CV + C C G G C ++ C PC A C+ Sbjct: 1722 DKCDVRIPDCIIANCSNGATCVNESNGFRCQCAVGFTGKFCEAIINPCAPSPCKNGATCI 1781 Query: 1564 PDQTPKGYSCACEPGYT----------LTTSGCIESGK-----EE----CPGGWWGGSAC 1604 + K Y C C +T ++S C+ G E+ CPGG++G Sbjct: 1782 REAHGK-YRCQCALDFTGFNCEIRVNNCSSSPCLHGGTCIDGFEDYNCTCPGGYYGKQ-- 1838 Query: 1605 GPCACDVTRGYHPHCNKENGKCHCKENHYKPE--GTAECLPCQCYAAGSENSSCEAATGQ 1662 C+ H K N C+ +++ Y G C AG + C + Sbjct: 1839 ----CETVDTCFAHACKNNATCNRRDSDYTCTCVGNFAGELCDSCTAGYTGADCNTPMKK 1894 Query: 1663 CHCRP 1667 C P Sbjct: 1895 CLTSP 1899 Score = 46.8 bits (106), Expect = 3e-04 Identities = 18/39 (46%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D Y C C G TGK+C Sbjct: 2709 CSVEIDECASNPCLNGATCTDRLGGYACSCIPGFTGKNC 2747 Score = 46.4 bits (105), Expect = 3e-04 Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C+S+PC+NG C DL + + C C G G+ C Sbjct: 814 CENQTNECASSPCFNGGTCHDLLNRFECVCPNGFLGRQC 852 Score = 46.4 bits (105), Expect = 3e-04 Identities = 48/191 (25%), Positives = 68/191 (35%), Gaps = 25/191 (13%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQ 1566 C+ R + C S C C+ ++ CTC G G QC V C C A C ++ Sbjct: 1801 CEIRVNNCSSSPCLHGGTCIDGFEDYNCTCPGGYYGKQCETVDTCFAHACKNNATC--NR 1858 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 Y+C C + C + C G+ G C + + C K NG C Sbjct: 1859 RDSDYTCTCVGNF--AGELC-----DSCTAGYTGAD----CNTPMKKCLTSPC-KNNGTC 1906 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAEVT 1685 + T C+ AG SCE +C P G C D+ ++A V Sbjct: 1907 YHDAQQPWTNRTCSCI------AGFTGMSCETDVDECLSSPCANGGTCSDSTSSASHFVG 1960 Query: 1686 PNSGCEVVYDG 1696 C Y+G Sbjct: 1961 FICACVQGYEG 1971 Score = 46.4 bits (105), Expect = 3e-04 Identities = 18/44 (40%), Positives = 25/44 (56%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 T C C+S PC NGA C+D ++Y C C G +GK+C+ Sbjct: 2311 TGVNCSVNIDDCASRPCKNGATCNDGVNSYTCSCAAGFSGKNCS 2354 Score = 45.6 bits (103), Expect = 6e-04 Identities = 18/39 (46%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C +APC NGA C +ICDCK G+TG C Sbjct: 942 CENLVTNCDTAPCQNGATCKIGAKGFICDCKAGYTGLAC 980 Score = 44.8 bits (101), Expect = 0.001 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 9/68 (13%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 F CQC GFTG CE I+ + S C++G+ C+ G CQ C++D +T Sbjct: 1749 FRCQCAVGFTGKFCEAIINPCA------PSPCKNGATCIREAHGKYRCQ-CALD--FTGF 1799 Query: 1102 VCELRARS 1109 CE+R + Sbjct: 1800 NCEIRVNN 1807 Score = 44.8 bits (101), Expect = 0.001 Identities = 18/41 (43%), Positives = 21/41 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C C S PC NGA C L + Y C C G TG++C D Sbjct: 2747 CETDLDECLSNPCGNGATCRHLVNNYTCICAVGFTGRNCLD 2787 Score = 44.4 bits (100), Expect = 0.001 Identities = 46/179 (25%), Positives = 61/179 (34%), Gaps = 21/179 (11%) Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSS---TCTCEAGRVGPQC---VSACELGP 1556 V E + D C + C+ I +CV + +C C G G C + C P Sbjct: 856 VVECLSDPCLNNGTCVEKIGVVGYQCVCPDGFAGDFSCACPVGYTGKLCEIDIDDCASMP 915 Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYH 1616 CG D YSCAC P YT + + + P G+ C A +G+ Sbjct: 916 CGNLSTCIDHV-NNYSCACVPWYTGRNCENLVTNCDTAP--CQNGATCKIGA----KGFI 968 Query: 1617 PHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 C C N EC C+ GS T C C PG G C+ Sbjct: 969 CDCKAGYTGLACTIN------IDECASSPCFNGGSCRDDVNGYT--CTCAPGYTGSRCE 1019 Score = 44.0 bits (99), Expect = 0.002 Identities = 16/39 (41%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CSS+PC +G C D ++ Y C C G+ GK C Sbjct: 1801 CEIRVNNCSSSPCLHGGTCIDGFEDYNCTCPGGYYGKQC 1839 Score = 43.6 bits (98), Expect = 0.002 Identities = 16/42 (38%), Positives = 23/42 (54%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 C C SAPC NGA C D + Y+C C +G +C+++ Sbjct: 2201 CTTNIDDCLSAPCKNGATCEDKVNGYLCKCPDGFHSTNCSEN 2242 Score = 43.2 bits (97), Expect = 0.003 Identities = 73/307 (23%), Positives = 111/307 (36%), Gaps = 54/307 (17%) Query: 1059 LTKASC--EVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL-RARSFPVSSF 1115 L K C E + C +G CVA G C A + CE A +F ++ Sbjct: 1455 LPKPGCRKETNCHAESCANGGTCVATWTGF----QCRCLAEFNGTRCENGTATTFLANTS 1510 Query: 1116 LTFPGLKR---RHRIHLKLKFATQTTSGLLLYNG--RYNERHDFLALELVSSEAGRGGGP 1170 GL R L+ T GLLLY G ++L ++LVS + Sbjct: 1511 SIQLGLNTTEWRFGQSGSLRVRTSRAIGLLLYAGWKPSGPNTEYLMVDLVSGK------- 1563 Query: 1171 GLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLK 1230 +R + LG G + V DG WH I + + +IL D + ++ + Sbjct: 1564 -VRLTADLGSGPGSVINPMTVNDGDWH--HITWSRQYKRLILSVDDVTMEMSTQGE---- 1616 Query: 1231 YACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK--DFVGCISDF 1288 + VL +E + + IGG P + SS + F GC+ D Sbjct: 1617 -------QSVLDVA---DSEIIY--------VHIGGFPYLKSSATGLSTITSFQGCLKDL 1658 Query: 1289 YIDHKFIDLNSYVADNGTLA-------GCPEKRSRCSSAPCYNGAECSDLWDTYICDCKE 1341 ++++ + + G + GC CSS PC + C + Y C C Sbjct: 1659 TFHYRYVHFLTPFSQQGLASILRNVTTGC-HSIGPCSSNPCQGYSTCENAGGAYNCTCLS 1717 Query: 1342 GHTGKDC 1348 G TG C Sbjct: 1718 GWTGDKC 1724 Score = 42.7 bits (96), Expect = 0.004 Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 18/196 (9%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC + C + C CTC G C + C+ PC + ++ Y+ Sbjct: 2093 DCAANPCLHGATCTDLVGGFVCTCALGYTDHNCSTIIDNCDPNPCNHSGICTNKI-GNYT 2151 Query: 1573 CACEPGYT-LTTSGCIE-SGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC--- 1626 C C+ GYT + I+ + C G S+ C GY +C C Sbjct: 2152 CLCKGGYTGWNCNTLIDFCYSDPCAYGATCVSSLADYTCACVPGYTGRNCTTNIDDCLSA 2211 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAEVT 1685 CK N E C+C G +++C +C P + G C D A+ YA V Sbjct: 2212 PCK-NGATCEDKVNGYLCKC-PDGFHSTNCSENINECDPNPCLNGATCLDKIAD-YACVC 2268 Query: 1686 PN--SG--CEVVYDGC 1697 P+ SG C V + C Sbjct: 2269 PSGYSGINCSVNVNDC 2284 Score = 42.7 bits (96), Expect = 0.004 Identities = 47/195 (24%), Positives = 65/195 (33%), Gaps = 16/195 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC + C + C+ + +CTC G C + C PC A CV D K Y Sbjct: 2487 DCATNPCRNGATCIDGINKYSCTCPIGFTDQICSTNIDDCATSPCRNGATCV-DGINK-Y 2544 Query: 1572 SCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKCHC 1628 SC C G+T T + + C G +C G+ C+ C Sbjct: 2545 SCTCPIGFTDQTCSTNIDDCATNPCRNGATCVDGINKYSCTCPIGFTDQTCSTNIDDCAT 2604 Query: 1629 KE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY-AEVT 1685 N C C AG +C+ +C RP +C N+Y Sbjct: 2605 NPCGNGATCVDEINKYSCLC-PAGFSGGNCQTNIDECASRPCANVGSCIDRINSYECTCV 2663 Query: 1686 P---NSGCEVVYDGC 1697 P C+V D C Sbjct: 2664 PGYTGRNCQVDIDEC 2678 Score = 42.3 bits (95), Expect = 0.005 Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C E + C PC NGA C D Y C C G++G +C+ Sbjct: 2239 CSENINECDPNPCLNGATCLDKIADYACVCPSGYSGINCS 2278 Score = 41.9 bits (94), Expect = 0.007 Identities = 16/31 (51%), Positives = 19/31 (61%) Query: 1319 SAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 + PC NGA C DL D Y C C G TG +C+ Sbjct: 2376 AGPCENGATCIDLVDGYRCSCSVGFTGTNCS 2406 Score = 41.5 bits (93), Expect = 0.009 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC N C D ++Y C C G+TG++C Sbjct: 2633 CQTNIDECASRPCANVGSCIDRINSYECTCVPGYTGRNC 2671 Score = 41.1 bits (92), Expect = 0.012 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 10/65 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + +TC CP GFTG NC L C + CR+G+ CV GI C+ A + Sbjct: 2427 INRYTCVCPTGFTGFNCS--LNIDDCSTNP----CRNGATCV----DGINKYSCTCPAGF 2476 Query: 1099 TTAVC 1103 T C Sbjct: 2477 TDQTC 2481 Score = 40.7 bits (91), Expect = 0.016 Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C++ PC +GA C+DL ++C C G+T +C+ Sbjct: 2087 CEINTDDCAANPCLHGATCTDLVGGFVCTCALGYTDHNCS 2126 Score = 40.7 bits (91), Expect = 0.016 Identities = 16/40 (40%), Positives = 20/40 (50%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C + C + PC NG C DL Y C C G TG +C+ Sbjct: 2277 CSVNVNDCRTNPCENGGTCIDLIGGYACTCAPGFTGVNCS 2316 Score = 40.7 bits (91), Expect = 0.016 Identities = 18/44 (40%), Positives = 21/44 (47%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 T C C S PC NGA C D + Y C C G TG +C+ Sbjct: 2401 TGTNCSTNIDDCYSDPCKNGASCVDGINRYTCVCPTGFTGFNCS 2444 Score = 39.9 bits (89), Expect = 0.029 Identities = 16/41 (39%), Positives = 21/41 (51%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A C + + C+S+PC N A C D+ C C G TG C Sbjct: 1972 ARCMNRTNVCASSPCQNNATCRDVMGHVKCTCPTGFTGALC 2012 Score = 39.9 bits (89), Expect = 0.029 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 1306 TLAGCPEKRSRCSSA--PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T A C + C S PC+NG CS+L +Y C+C G G+ C Sbjct: 2819 TGARCNIDVNECQSLEQPCFNGGTCSNLDGSYSCECPRGFAGRLC 2863 Score = 39.1 bits (87), Expect = 0.050 Identities = 36/166 (21%), Positives = 64/166 (38%), Gaps = 16/166 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C++ D C+ + C + C ++ TC C G G C ++ C PC +C + Sbjct: 2747 CETDLDECLSNPCGNGATCRHLVNNYTCICAVGFTGRNCLDDINECGSDPCVHGKC--NN 2804 Query: 1567 TPKGYSCACE-PGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-C 1619 T ++C C G+T + + C +S ++ C G + G +C+ RG+ C Sbjct: 2805 TIGSFACDCSGTGFTGARCNIDVNEC-QSLEQPCFNGGTCSNLDGSYSCECPRGFAGRLC 2863 Query: 1620 NKENGKCHCKE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663 + +C + K + C C G C +C Sbjct: 2864 ELDVDECASSPCLHGGKCINLKDQFICHCVGTGFTGFRCGLDVDEC 2909 Score = 38.7 bits (86), Expect = 0.066 Identities = 15/43 (34%), Positives = 20/43 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C + C S PC N C D Y C C G+ G++C +T Sbjct: 2049 CQVDINECQSFPCLNSGTCRDEVGNYSCRCPYGYEGRNCEINT 2091 Score = 38.7 bits (86), Expect = 0.066 Identities = 15/33 (45%), Positives = 19/33 (57%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 CS+ PC NGA C D + Y C C G T + C+ Sbjct: 2450 CSTNPCRNGATCVDGINKYSCTCPAGFTDQTCS 2482 Score = 38.7 bits (86), Expect = 0.066 Identities = 15/40 (37%), Positives = 21/40 (52%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C+++PC NGA C D + Y C C G T + C+ Sbjct: 2519 CSTNIDDCATSPCRNGATCVDGINKYSCTCPIGFTDQTCS 2558 Score = 38.7 bits (86), Expect = 0.066 Identities = 15/40 (37%), Positives = 19/40 (47%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C S PC NG C D Y C C G+T ++C+ Sbjct: 2671 CQVDIDECESKPCVNGGTCIDRVAGYSCACAVGYTDQNCS 2710 Score = 38.3 bits (85), Expect = 0.088 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 9/67 (13%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + FTC+C +GF G C + K C + C++G++C ++GG C + + Sbjct: 605 INGFTCKCQDGFIGDRCHAFINK--CLFNP----CKNGAKCQTLQDGG---HRCLCEKGF 655 Query: 1099 TTAVCEL 1105 ++CE+ Sbjct: 656 KGSLCEV 662 Score = 38.3 bits (85), Expect = 0.088 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Query: 1012 ECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGS 1071 +C T +K S N+ + P T+ TC C GFTG++CET + + +G Sbjct: 1887 DCNTPMKKCLTSPCKNNGTCYHDAQQPWTNRTCSCIAGFTGMSCETDVDECLSSPCANGG 1946 Query: 1072 ICRSGSQCVARREGGILC 1089 C S S A G +C Sbjct: 1947 TC-SDSTSSASHFVGFIC 1963 Score = 37.9 bits (84), Expect = 0.12 Identities = 49/191 (25%), Positives = 70/191 (36%), Gaps = 25/191 (13%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTC-TCEAGRVGPQC---VSACELGPC-GAARCVPD 1565 C++ A C CV ++ C +C AG G C + C PC C D Sbjct: 1850 CKNNATCNRRDSDYTCTCVGNFAGELCDSCTAGYTGADCNTPMKKCLTSPCKNNGTCYHD 1909 Query: 1566 -QTP-KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKEN 1623 Q P +C+C G+T C E+ +EC G C+ + H Sbjct: 1910 AQQPWTNRTCSCIAGFT--GMSC-ETDVDECLSSPCANG--GTCSDSTSSASH----FVG 1960 Query: 1624 GKCHCKENHYKPEGTAECLPCQCYAAGS---ENSSCEAATG--QCHCRPGVIGRACDACA 1678 C C + + EG A C+ A S N++C G +C C G G C+ Sbjct: 1961 FICACVQGY---EG-ARCMNRTNVCASSPCQNNATCRDVMGHVKCTCPTGFTGALCETDI 2016 Query: 1679 NAYAEVTPNSG 1689 N A N+G Sbjct: 2017 NECASNPCNNG 2027 Score = 37.5 bits (83), Expect = 0.15 Identities = 15/40 (37%), Positives = 20/40 (50%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C++ PC NGA C D + Y C C G T + C+ Sbjct: 2557 CSTNIDDCATNPCRNGATCVDGINKYSCTCPIGFTDQTCS 2596 Score = 37.5 bits (83), Expect = 0.15 Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C++ PC NGA C D + Y C C G +G +C Sbjct: 2595 CSTNIDDCATNPCGNGATCVDEINKYSCLCPAGFSGGNC 2633 Score = 37.5 bits (83), Expect = 0.15 Identities = 15/33 (45%), Positives = 19/33 (57%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICR 1074 + C C GFTG NCET L + G+G+ CR Sbjct: 2734 YACSCIPGFTGKNCETDLDECLSNPCGNGATCR 2766 Score = 37.5 bits (83), Expect = 0.15 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDC-KEGHTGKDC 1348 C C+S+PC +G +C +L D +IC C G TG C Sbjct: 2863 CELDVDECASSPCLHGGKCINLKDQFICHCVGTGFTGFRC 2902 Score = 37.1 bits (82), Expect = 0.20 Identities = 45/187 (24%), Positives = 63/187 (33%), Gaps = 24/187 (12%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPK-GYSCA 1574 DC C + C +S TC+C AG G C + + C + C T K G + Sbjct: 2321 DCASRPCKNGATCNDGVNSYTCSCAAGFSGKNC--SHNIDDCFSMPCKHGATCKDGVAGP 2378 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634 CE G T ++ + C G+ G + C+ ++ Y C K C N Y Sbjct: 2379 CENG--ATCIDLVDGYRCSCSVGFTGTN----CSTNIDDCYSDPC-KNGASCVDGINRY- 2430 Query: 1635 PEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP----NSGC 1690 C C G +C C P G C N Y+ P + C Sbjct: 2431 --------TCVC-PTGFTGFNCSLNIDDCSTNPCRNGATCVDGINKYSCTCPAGFTDQTC 2481 Query: 1691 EVVYDGC 1697 D C Sbjct: 2482 STNIDDC 2488 Score = 36.7 bits (81), Expect = 0.27 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 6/49 (12%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT------YICDCKEGHTGKDCADST 1352 C C S+PC NG CSD + +IC C +G+ G C + T Sbjct: 1930 CETDVDECLSSPCANGGTCSDSTSSASHFVGFICACVQGYEGARCMNRT 1978 Score = 36.7 bits (81), Expect = 0.27 Identities = 15/40 (37%), Positives = 20/40 (50%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C++ PC NGA C D + Y C C G T + C+ Sbjct: 2481 CSTNIDDCATNPCRNGATCIDGINKYSCTCPIGFTDQICS 2520 Score = 36.7 bits (81), Expect = 0.27 Identities = 31/111 (27%), Positives = 43/111 (38%), Gaps = 19/111 (17%) Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRP-------IYPVTSFTCQCPEGFTGVN 1054 CV E +N CL F + N D RP I + S+ C C G+TG N Sbjct: 2613 CVDE--INKYSCLCPAGFSGGNCQTNIDECASRPCANVGSCIDRINSYECTCVPGYTGRN 2670 Query: 1055 CETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105 C+ + + CE C +G C+ R G C+ YT C + Sbjct: 2671 CQVDIDE--CE----SKPCVNGGTCIDRVAG----YSCACAVGYTDQNCSV 2711 Score = 36.3 bits (80), Expect = 0.35 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC C D D+Y C C G+TG C Sbjct: 738 CEININDCASNPCAAYQRCIDRIDSYTCACPLGYTGNAC 776 Score = 36.3 bits (80), Expect = 0.35 Identities = 14/32 (43%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S PC GA C Y C C G+TG++C Sbjct: 2170 CYSDPCAYGATCVSSLADYTCACVPGYTGRNC 2201 Score = 35.5 bits (78), Expect = 0.62 Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T A C + C+S PC NG C Y C C +G TG++C Sbjct: 2008 TGALCETDINECASNPCNNGT-CLQGIGRYDCSCFQGFTGQNC 2049 Score = 35.1 bits (77), Expect = 0.82 Identities = 15/32 (46%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S PC +GA C D Y C C G TG +C Sbjct: 707 CISNPCIHGATCHDGLLGYSCACAVGFTGINC 738 Score = 35.1 bits (77), Expect = 0.82 Identities = 14/43 (32%), Positives = 17/43 (39%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C C+S PC N C D + C C G G C + T Sbjct: 776 CDVNIDECASQPCLNNGTCQDGRGNFSCVCPAGFEGLRCENQT 818 Score = 35.1 bits (77), Expect = 0.82 Identities = 13/32 (40%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S PC N + C D + Y C C +TG++C Sbjct: 911 CASMPCGNLSTCIDHVNNYSCACVPWYTGRNC 942 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/41 (34%), Positives = 18/41 (43%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A C C S PCY C D + + C C++G G C Sbjct: 581 ATCDIDIDECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRC 621 Score = 34.7 bits (76), Expect = 1.1 Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 10/65 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + ++C CP GFT C T + C + CR+G+ C+ GI C+ + Sbjct: 2465 INKYSCTCPAGFTDQTCSTNID--DCATNP----CRNGATCI----DGINKYSCTCPIGF 2514 Query: 1099 TTAVC 1103 T +C Sbjct: 2515 TDQIC 2519 Score = 33.9 bits (74), Expect = 1.9 Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG---GILCQGCSIDAAY 1098 + C CP G+ G CET+ T + + + R S G G LC C+ A Y Sbjct: 1826 YNCTCPGGYYGKQCETVDTCFAHACKNNATCNRRDSDYTCTCVGNFAGELCDSCT--AGY 1883 Query: 1099 TTAVC 1103 T A C Sbjct: 1884 TGADC 1888 Score = 33.9 bits (74), Expect = 1.9 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V + C C GFTG NC T + C D C++G+ CV GI C + Sbjct: 2389 VDGYRCSCSVGFTGTNCSTNID--DCYSDP----CKNGASCV----DGINRYTCVCPTGF 2438 Query: 1099 TTAVCEL 1105 T C L Sbjct: 2439 TGFNCSL 2445 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDCADST-GPP 1355 C + A C++L Y C C EG+ G+ C + T PP Sbjct: 2916 CMHNATCTNLEGGYRCTCVEGYFGEHCENGTLAPP 2950 Score = 33.5 bits (73), Expect = 2.5 Identities = 33/128 (25%), Positives = 46/128 (35%), Gaps = 16/128 (12%) Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061 C+ +PCLN C+ + G V V P F+C CP G+TG CE + Sbjct: 859 CLSDPCLNNGTCVEKI------GVVGYQCVC--PDGFAGDFSCACPVGYTGKLCEIDIDD 910 Query: 1062 ASCEVDGDGSIC-----RSGSQCV---ARREGGILCQGCSIDAAYTTAVCELRARSFPVS 1113 + G+ S C CV R L C A C++ A+ F Sbjct: 911 CASMPCGNLSTCIDHVNNYSCACVPWYTGRNCENLVTNCDTAPCQNGATCKIGAKGFICD 970 Query: 1114 SFLTFPGL 1121 + GL Sbjct: 971 CKAGYTGL 978 Score = 33.5 bits (73), Expect = 2.5 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C PC + C++ Y C CK G+TG +C Sbjct: 2125 CSTIIDNCDPNPCNHSGICTNKIGNYTCLCKGGYTGWNC 2163 Score = 33.5 bits (73), Expect = 2.5 Identities = 12/38 (31%), Positives = 18/38 (47%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 + + C C GFTGVNC + + +G+ C G Sbjct: 2299 IGGYACTCAPGFTGVNCSVNIDDCASRPCKNGATCNDG 2336 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/47 (31%), Positives = 18/47 (38%), Gaps = 4/47 (8%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAEC----SDLWDTYICDCKEGHTGKDC 1348 T A C +C ++PC N C W C C G TG C Sbjct: 1884 TGADCNTPMKKCLTSPCKNNGTCYHDAQQPWTNRTCSCIAGFTGMSC 1930 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/52 (28%), Positives = 23/52 (44%) Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSID 1095 C CP GFTG CET + + + +G+ + + G Q C +D Sbjct: 2001 CTCPTGFTGALCETDINECASNPCNNGTCLQGIGRYDCSCFQGFTGQNCQVD 2052 Score = 33.1 bits (72), Expect = 3.3 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 10/65 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + ++C CP GFT C T + C + CR+G+ CV GI C+ + Sbjct: 2541 INKYSCTCPIGFTDQTCSTNID--DCATNP----CRNGATCV----DGINKYSCTCPIGF 2590 Query: 1099 TTAVC 1103 T C Sbjct: 2591 TDQTC 2595 Score = 32.7 bits (71), Expect = 4.4 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 10/65 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + ++C CP GFT C T + D S CR+G+ CV GI C+ + Sbjct: 2503 INKYSCTCPIGFTDQICSTNID------DCATSPCRNGATCV----DGINKYSCTCPIGF 2552 Query: 1099 TTAVC 1103 T C Sbjct: 2553 TDQTC 2557 Score = 32.3 bits (70), Expect = 5.8 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 1315 SRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348 ++C PC NGA+C L D + C C++G G C Sbjct: 626 NKCLFNPCKNGAKCQTLQDGGHRCLCEKGFKGSLC 660 Score = 32.3 bits (70), Expect = 5.8 Identities = 13/43 (30%), Positives = 23/43 (53%) Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 R I + S+TC CP G+TG C+ + + + + + C+ G Sbjct: 755 RCIDRIDSYTCACPLGYTGNACDVNIDECASQPCLNNGTCQDG 797 Score = 32.3 bits (70), Expect = 5.8 Identities = 11/35 (31%), Positives = 18/35 (51%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073 + ++C CP GFT C T + + G+G+ C Sbjct: 2579 INKYSCTCPIGFTDQTCSTNIDDCATNPCGNGATC 2613 Score = 31.9 bits (69), Expect = 7.6 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS-----GSQCVARREGGILCQGCSIDA 1096 F C CP GF G CE + + + + C G QCV +G C+ Sbjct: 839 FECVCPNGFLGRQCEANVVECLSDPCLNNGTCVEKIGVVGYQCVC-PDGFAGDFSCACPV 897 Query: 1097 AYTTAVCEL 1105 YT +CE+ Sbjct: 898 GYTGKLCEI 906 Score = 31.9 bits (69), Expect = 7.6 Identities = 23/97 (23%), Positives = 33/97 (34%), Gaps = 8/97 (8%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC---RSGSQCV-ARREGGILC----Q 1090 + + C CP G++G+NC + +G C G C A G+ C Sbjct: 2261 IADYACVCPSGYSGINCSVNVNDCRTNPCENGGTCIDLIGGYACTCAPGFTGVNCSVNID 2320 Query: 1091 GCSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRI 1127 C+ A C S+ S F G H I Sbjct: 2321 DCASRPCKNGATCNDGVNSYTCSCAAGFSGKNCSHNI 2357 >SB_4874| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 473 Score = 72.9 bits (171), Expect = 3e-12 Identities = 62/201 (30%), Positives = 89/201 (44%), Gaps = 18/201 (8%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F Q+ E+ E+ G V T+ A + ++ YE+ N T + G ITV Sbjct: 220 FFSKQHSAEVRENSRRGAYVTTVRAVSFSKPRKIRYELIAENLLPPTHFTIEETTGTITV 279 Query: 426 AQPLDFKQERRYVLTVSA---TDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFE 480 A LD +++ Y+L V A +G S A V + I+D N+ P+F Y V Sbjct: 280 AGDLDREEKDSYLLEVGAGLQYPNGTLSRVARTYVMVKISDENDNYPIFGLPSYHVRVPC 339 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + G TV V+A D D+G NA+I Y L + + F I P TG I + L Sbjct: 340 NTTAGRTVYRVTAMDRDLGDNARIRYRLQPK---------NMYFTILPHTGKIRVTQDLH 390 Query: 541 R----ETMSGYLLTVTARDGG 557 R G+ L+V ARD G Sbjct: 391 RFCNMRPARGFTLSVLARDYG 411 Score = 72.5 bits (170), Expect = 4e-12 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 13/185 (7%) Query: 504 ITYSLSSEISNEAVAHH---DQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR---DGG 557 +++S +I E +A + F I TG IT LDRE YLL V A G Sbjct: 245 VSFSKPRKIRYELIAENLLPPTHFTIEETTGTITVAGDLDREEKDSYLLEVGAGLQYPNG 304 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 S T V + + D NDN P+F Y + + G +V +V A D D+G N RI Sbjct: 305 TLSRVARTYVMVKISDENDNYPIFGLPSYHVRVPCNTTAGRTVYRVTAMDRDLGDNARIR 364 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDR----ESVATHDLKAVAIDGGTPPQSSTVIV 673 Y L PK+ F I P +G IR + L R L +A D G P+++ + Sbjct: 365 YRLQPKNM---YFTILPHTGKIRVTQDLHRFCNMRPARGFTLSVLARDYGKLPETAHAWM 421 Query: 674 HIKIE 678 +I+++ Sbjct: 422 YIEVK 426 Score = 64.1 bits (149), Expect = 2e-09 Identities = 53/173 (30%), Positives = 79/173 (45%), Gaps = 15/173 (8%) Query: 187 IRYAIIGGNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA---QDGGSPSRSNTT 241 IRY +I N F+I+ +G +++ LD E+ SY L + A G+ SR T Sbjct: 253 IRYELIAENLLPPTHFTIEETTGTITVAGDLDREEKDSYLLEVGAGLQYPNGTLSRVART 312 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 +++ I D NDN P F + V N G ++ RV A D D G NA + Y + K Sbjct: 313 YVMVKISDENDNYPIFGLPSYHVRVPCNTTAGRTVYRVTAMDRDLGDNARIRYRLQPK-- 370 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATA 350 ++ TI P +G + + L R + + L V A D G P +A A Sbjct: 371 ----NMYFTILPHTGKIRVTQDLHRFCNMRPARGFTLSVLARDYGKLPETAHA 419 Score = 60.9 bits (141), Expect = 1e-08 Identities = 62/231 (26%), Positives = 102/231 (44%), Gaps = 29/231 (12%) Query: 23 FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXX 82 F +Q+ A VRE + G V T++A K ++ Y EL+ + L P Sbjct: 220 FFSKQHSAEVRENSRRGAYVTTVRAVS--FSKPRKIRY--ELIAENLLPPTH-------- 267 Query: 83 XXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ-ASPVSDRLSSTATIHVNII 141 F I+ +G + LDRE+ Y + V A Q + R++ T + V I Sbjct: 268 -------FTIEETTGTITVAGDLDREEKDSYLLEVGAGLQYPNGTLSRVARTYVM-VKIS 319 Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201 D+NDNYP F +Y V V + T + ++ A D D+G N+ IRY + N M F+ Sbjct: 320 DENDNYPIFGLPSYHVRV--PCNTTAGRTVYRVTAMDRDLGDNARIRYRLQPKN--MYFT 375 Query: 202 IDSLSGDVSLVKTL----DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I +G + + + L + R + L + A+D G + + I ++ Sbjct: 376 ILPHTGKIRVTQDLHRFCNMRPARGFTLSVLARDYGKLPETAHAWMYIEVK 426 Score = 49.2 bits (112), Expect = 5e-05 Identities = 41/151 (27%), Positives = 69/151 (45%), Gaps = 6/151 (3%) Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVI 639 F + ++A + E++ G V+ V A +I YEL ++ + F I+ +G I Sbjct: 220 FFSKQHSAEVRENSRRGAYVTTVRAVS--FSKPRKIRYELIAENLLPPTHFTIEETTGTI 277 Query: 640 RTNKALDRESVATHDLKAVA---IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 LDRE ++ L+ A GT + + V +KI D ND+ P+F + Sbjct: 278 TVAGDLDREEKDSYLLEVGAGLQYPNGTLSRVARTYVMVKISDENDNYPIFGLPSYHVRV 337 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 N+ G T+ + A D D G NA + Y ++ Sbjct: 338 PCNTTAGRTVYRVTAMDRDLGDNARIRYRLQ 368 Score = 42.7 bits (96), Expect = 0.004 Identities = 17/53 (32%), Positives = 30/53 (56%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63 + + D ND+ P+F + Y V ++G TV + A D+D+G NA + Y ++ Sbjct: 316 VKISDENDNYPIFGLPSYHVRVPCNTTAGRTVYRVTAMDRDLGDNARIRYRLQ 368 Score = 37.1 bits (82), Expect = 0.20 Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 9/78 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAG------RVGPQCVSACELGPCGAARCVPD--QT 1567 +C +C C + S C C G R +CV E G GAARC T Sbjct: 136 ECERPVCSFPRLCRNTLGSYACDCPEGYENRGRRDSDKCVDIDECGS-GAARCDHKCVNT 194 Query: 1568 PKGYSCACEPGYTLTTSG 1585 Y C C GYTL G Sbjct: 195 EGSYHCRCRKGYTLAPDG 212 >SB_23044| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2162 Score = 71.3 bits (167), Expect = 1e-11 Identities = 77/275 (28%), Positives = 111/275 (40%), Gaps = 32/275 (11%) Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDL-WDTYICDCKEGHTGKDCADSTG 1353 D + N T C ++RC PC NG C D+ ++ + CDC G G C +ST Sbjct: 908 DFSCNCTANYTGRQCEYLKTRCRPINPCLNGGRCKDIGFENFTCDCSAGFGGPLCENSTT 967 Query: 1354 PPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS-------IQLKSGLLHYSY 1406 G L+F+ Q ++ AL RT D ++ +QLK G + S Sbjct: 968 VS--LNGSSYLTFDGS----QSEFMVALEFRTTLADGVLVHDSESKFLMQLKEGAIEIS- 1020 Query: 1407 NGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466 NG A LSDG W I ++ T + + +V + + N+ K+ IG Sbjct: 1021 NGVNSAAIGAALSDGNWSGI-VRLNVTQSHLQLSINTSSVSITRI-NRTNP----KLFIG 1074 Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRD--GCQSRADCMLSICPP 1524 G +G L S GCI+DV++ L P+ E VR GC C C Sbjct: 1075 GY---SGNLQSSRNLI-GCIRDVKVNGVVKL---PSEIELVRVSMGCPREEVCSPDPCTN 1127 Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGA 1559 C+ W + C C GP C ++ G GA Sbjct: 1128 -GTCIDEWLTYRCACYRRWTGPNCSTSFVAGTFGA 1161 Score = 55.6 bits (128), Expect = 5e-07 Identities = 44/170 (25%), Positives = 68/170 (40%), Gaps = 17/170 (10%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC ++C + CV ++ TC C +G G C ++ CE PC ++ K ++ Sbjct: 620 DCASALCVANATCVDLLNNYTCKCPSGYHGDLCQFDINECESNPCRNNGTCKNEEGK-FT 678 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGYH-PHCNKENGKC- 1626 C C G+ T C E ++CP C C G+ HC K+ +C Sbjct: 679 CTCLSGFNGTF--C-EVNIDDCPAIGCNNGTCIDGINNYTCQCFIGFEGRHCEKDIDECS 735 Query: 1627 --HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 +CK N T CQC + ++CE +C P + G C Sbjct: 736 LGYCK-NGATCTNTPGNYSCQC-TEFTNGTNCELDINECASSPCLNGALC 783 Score = 50.4 bits (115), Expect = 2e-05 Identities = 18/39 (46%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C R +C S PC NG C D Y C C+ HTGK+C Sbjct: 2007 CDILRDKCDSNPCQNGGRCKSTRDGYTCQCEPSHTGKNC 2045 Score = 48.4 bits (110), Expect = 8e-05 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 10/98 (10%) Query: 1256 LDLTGP-LQIGGLP-NIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEK 1313 ++ T P L IGG N+ SS ++ +GCI D ++ + L S + GCP + Sbjct: 1064 INRTNPKLFIGGYSGNLQSS-----RNLIGCIRDVKVNG-VVKLPSEIELVRVSMGCPRE 1117 Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 CS PC NG C D W TY C C TG +C+ S Sbjct: 1118 EV-CSPDPCTNGT-CIDEWLTYRCACYRRWTGPNCSTS 1153 Score = 46.0 bits (104), Expect = 4e-04 Identities = 67/303 (22%), Positives = 120/303 (39%), Gaps = 38/303 (12%) Query: 1379 NALSIRTRQRDAFVMSIQLKSGLLH--YSYNGETMYLPMATL-SDGAWHRIEIKWLGTDI 1435 NA+ +++RQ + + ++L+SG L+ Y++ G T + + ++G W+ + T + Sbjct: 1502 NAVLLQSRQDASNFLEVRLESGYLNVTYAFGGNTGTVKTGVVVNNGEWYHVTFNATST-L 1560 Query: 1436 SVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQ 1495 ++V+ + +G + G L L +T FF+GC+ +VR+G A Sbjct: 1561 LLSVNQS---------QTEKEGSFTGTELQNLLASTPISFGLAQPFFKGCLDNVRVGGA- 1610 Query: 1496 SLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG 1555 LL P + + S+ P + VTS + C + AC + Sbjct: 1611 -LL--PFIPYY---NATYNVSHVTSLKPRFD--VTSINGINTGCRSD-------DACAVR 1655 Query: 1556 PCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECP-GGWWGGSAC-GPCACDVTR 1613 PC +C D + CAC GY C + C + GS C A ++T+ Sbjct: 1656 PCMRGQCSDDW--NAFKCACPEGYAGMV--CNLTANMTCAHAPCFNGSTCENRTAANLTQ 1711 Query: 1614 GYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGR 1672 + + CHC + A C+ G+ + ++ C C G GR Sbjct: 1712 --ISNVGIDQFVCHCAPGFEGRQCNATTDECKSNPCGNYGTCTDSHLNYSCACVSGFTGR 1769 Query: 1673 ACD 1675 C+ Sbjct: 1770 NCE 1772 Score = 44.8 bits (101), Expect = 0.001 Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 20/153 (13%) Query: 1533 DSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIES 1589 D C C G G QC C+ PCG D + YSCAC G+ T C E Sbjct: 1718 DQFVCHCAPGFEGRQCNATTDECKSNPCGNYGTCTD-SHLNYSCACVSGF--TGRNC-EI 1773 Query: 1590 GKEECPG-GWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 ++C G S C D+ Y+ C +C+ + ECL C + Sbjct: 1774 DIDDCVGNNCTNNSTC----VDLIDDYNCTCQVGYNGSYCELD------IDECLANPCSS 1823 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 GS N++ + +C C+ G G C A+ + Sbjct: 1824 YGSCNNT--IGSYECVCKQGYYGNHCQYNASQW 1854 Score = 44.0 bits (99), Expect = 0.002 Identities = 44/162 (27%), Positives = 63/162 (38%), Gaps = 16/162 (9%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCE-AGRVGPQC---VSACEL--GPC-GAARCV 1563 C+ D S+ + KCV ++ TC C +G GP+C ++ C++ GPC C Sbjct: 313 CEQNIDDCASLPCKHGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNGGTC- 371 Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGG--SACGPCACDVTRGYHPHCNK 1621 D Y C+C+ GY C E+ E P G S C A G H +K Sbjct: 372 -DNYLGTYGCSCKAGY--RGKNCQENIDECDPNPCLNGATSRCTRPAIVCAIGRPRHMSK 428 Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663 N C+ + +G C C+ G CE C Sbjct: 429 -NFLCYLLPSGTCVDG-INGFNCSCF-IGFTGERCETNIDDC 467 Score = 44.0 bits (99), Expect = 0.002 Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C S PC + A C+DL + + C+C +TG+ C Sbjct: 884 CSEDINECLSTPCQHNATCNDLVNDFSCNCTANYTGRQC 922 Score = 44.0 bits (99), Expect = 0.002 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 6/68 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGA-ARCVPDQTPKGY 1571 DC+ + C S CV D CTC+ G G C + C PC + C + T Y Sbjct: 1777 DCVGNNCTNNSTCVDLIDDYNCTCQVGYNGSYCELDIDECLANPCSSYGSC--NNTIGSY 1834 Query: 1572 SCACEPGY 1579 C C+ GY Sbjct: 1835 ECVCKQGY 1842 Score = 43.6 bits (98), Expect = 0.002 Identities = 44/167 (26%), Positives = 59/167 (35%), Gaps = 24/167 (14%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC+ + C CV ++ TC C+ G G C + C PC C + GY Sbjct: 466 DCVSNTCNANQDCVDQVNNYTCVCKPGFTGSDCSVDILECLSNPCRHGGTC--HEGVNGY 523 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSAC---GPCACDVTRGYHPHCNKENGKCHC 1628 +C C P + T C +C S C G C DV ++ C K C Sbjct: 524 NCTCLPRFNGT--HCELDTVNDC-----NSSPCLNNGTCVDDV-GFFNCTCPKGFDGVRC 575 Query: 1629 KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 + + C P C S N E C C G G+ CD Sbjct: 576 ENK------SDSCHPNPCKHGASCNIVNE-TDFTCACPTGYTGKTCD 615 Score = 42.7 bits (96), Expect = 0.004 Identities = 17/47 (36%), Positives = 25/47 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPW 1356 C C+SAPC++ + C D + Y C C TG+DC+ + G W Sbjct: 209 CEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLW 255 Score = 41.9 bits (94), Expect = 0.007 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 NG GC C+ PC G +CSD W+ + C C EG+ G C Sbjct: 1640 NGINTGC-RSDDACAVRPCMRG-QCSDDWNAFKCACPEGYAGMVC 1682 Score = 41.5 bits (93), Expect = 0.009 Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 15/124 (12%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQ 1566 C+ D +I C+ ++ TC C G G C + C LG C A C Sbjct: 690 CEVNIDDCPAIGCNNGTCIDGINNYTCQCFIGFEGRHCEKDIDECSLGYCKNGATCT--N 747 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNKENGK 1625 TP YSC C +T T+ C E EC G+ C CD T C+ + + Sbjct: 748 TPGNYSCQCTE-FTNGTN-C-ELDINECASSPCLNGALCQNNDCDKTA-----CSDKGYE 799 Query: 1626 CHCK 1629 C CK Sbjct: 800 CFCK 803 Score = 41.1 bits (92), Expect = 0.012 Identities = 14/31 (45%), Positives = 19/31 (61%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 PC NG C + TY C CK G+ GK+C ++ Sbjct: 364 PCLNGGTCDNYLGTYGCSCKAGYRGKNCQEN 394 Score = 40.7 bits (91), Expect = 0.016 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C+ +PC G C+D W+ Y C C + G DC+ Sbjct: 1354 CARSPCGMGGTCNDRWNKYECSCSPRYGGPDCS 1386 Score = 39.9 bits (89), Expect = 0.029 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348 C K C PC +GA C+ + +T + C C G+TGK C Sbjct: 575 CENKSDSCHPNPCKHGASCNIVNETDFTCACPTGYTGKTC 614 Score = 39.9 bits (89), Expect = 0.029 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S C+ PC NG C L D YIC+C + G++C Sbjct: 1970 CSGLLSYCTPNPCING-NCIPLMDNYICECDSKYLGRNC 2007 Score = 39.5 bits (88), Expect = 0.038 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 11/108 (10%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V F+C C +TG CE + T+ C C +G +C ++ G C A + Sbjct: 906 VNDFSCNCTANYTGRQCEYLKTR--CRPINP---CLNGGRC---KDIGFENFTCDCSAGF 957 Query: 1099 TTAVCELRAR-SFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN 1145 +CE S SS+LTF G + + L+F T G+L+++ Sbjct: 958 GGPLCENSTTVSLNGSSYLTFDGSQSEFMV--ALEFRTTLADGVLVHD 1003 Score = 38.3 bits (85), Expect = 0.088 Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C S PC N C+D Y C C G TG++C Sbjct: 1733 CNATTDECKSNPCGNYGTCTDSHLNYSCACVSGFTGRNC 1771 Score = 37.9 bits (84), Expect = 0.12 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C C S C +C D + Y C CK G TG DC+ + P R GG Sbjct: 460 CETNIDDCVSNTCNANQDCVDQVNNYTCVCKPGFTGSDCSVDILECLSNPCRHGG 514 Score = 37.5 bits (83), Expect = 0.15 Identities = 42/182 (23%), Positives = 67/182 (36%), Gaps = 21/182 (11%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA-CE-LGPCGAARCVPDQTP 1568 C + A C + Y C W+ C+ + +C S C+ G C + V + P Sbjct: 1861 CMNNATCSGNATGFYCTCAEGWEGKLCSVDI----KECESTPCQNNGTCTDSHSVSEFFP 1916 Query: 1569 KGYSCACEPGYTLTTSGCIESGKEECP---GGWWGGSACGPCACDVTRGYHPHCNKENGK 1625 GY CAC YT + + + +E P G + C+ T GY + N Sbjct: 1917 -GYRCACTVDYTGPSCEKLVTPCDEKPCLNNGSCIRLSYNKYECNCTEGY-GNMNCSGLL 1974 Query: 1626 CHCKENHYKPEGTAECLP------CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 +C N P C+P C+C + +C+ +C P G C + + Sbjct: 1975 SYCTPN---PCINGNCIPLMDNYICEC-DSKYLGRNCDILRDKCDSNPCQNGGRCKSTRD 2030 Query: 1680 AY 1681 Y Sbjct: 2031 GY 2032 Score = 35.9 bits (79), Expect = 0.47 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 14/105 (13%) Query: 1002 CVHEPCLNFEEC-LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILT 1060 C P N C L + N+S +N+ + + V F C CP+GF GV CE Sbjct: 525 CTCLPRFNGTHCELDTVNDCNSSPCLNNGTC----VDDVGFFNCTCPKGFDGVRCEN--K 578 Query: 1061 KASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105 SC + C+ G+ C E C+ YT C++ Sbjct: 579 SDSCHPNP----CKHGASCNIVNETDFT---CACPTGYTGKTCDI 616 Score = 35.5 bits (78), Expect = 0.62 Identities = 14/32 (43%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+SA C A C DL + Y C C G+ G C Sbjct: 621 CASALCVANATCVDLLNNYTCKCPSGYHGDLC 652 Score = 35.1 bits (77), Expect = 0.82 Identities = 14/39 (35%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + CS C NGA C++ Y C C E G +C Sbjct: 727 CEKDIDECSLGYCKNGATCTNTPGNYSCQCTEFTNGTNC 765 Score = 34.7 bits (76), Expect = 1.1 Identities = 20/70 (28%), Positives = 26/70 (37%), Gaps = 3/70 (4%) Query: 1514 RADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKG 1570 R C + C +C ++ D TC CE G C S C PC C Sbjct: 2011 RDKCDSNPCQNGGRCKSTRDGYTCQCEPSHTGKNCQLPSPCFRNPCENNGVCKIHPVHFN 2070 Query: 1571 YSCACEPGYT 1580 Y+C C +T Sbjct: 2071 YTCNCTDTFT 2080 Score = 34.3 bits (75), Expect = 1.4 Identities = 13/32 (40%), Positives = 16/32 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C N + C DL D Y C C+ G+ G C Sbjct: 1778 CVGNNCTNNSTCVDLIDDYNCTCQVGYNGSYC 1809 Score = 34.3 bits (75), Expect = 1.4 Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDL-WDTYICDCKEGHTGKDCA 1349 C + + C PC N C L ++ Y C+C EG+ +C+ Sbjct: 1931 CEKLVTPCDEKPCLNNGSCIRLSYNKYECNCTEGYGNMNCS 1971 Score = 33.9 bits (74), Expect = 1.9 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 11/80 (13%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVP- 1564 C+ D C L C + C + + +C C G C ++ C PC A C Sbjct: 727 CEKDIDECSLGYCKNGATCTNTPGNYSCQCTEFTNGTNCELDINECASSPCLNGALCQNN 786 Query: 1565 --DQTP---KGYSCACEPGY 1579 D+T KGY C C+ G+ Sbjct: 787 DCDKTACSDKGYECFCKSGF 806 Score = 33.9 bits (74), Expect = 1.9 Identities = 17/70 (24%), Positives = 34/70 (48%), Gaps = 10/70 (14%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 ++ C+C + G NC+ + K D + C++G +C + R+G C + ++T Sbjct: 1993 NYICECDSKYLGRNCDILRDKC------DSNPCQNGGRCKSTRDG----YTCQCEPSHTG 2042 Query: 1101 AVCELRARSF 1110 C+L + F Sbjct: 2043 KNCQLPSPCF 2052 Score = 33.5 bits (73), Expect = 2.5 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 10/65 (15%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 +++C C GFTG NCE + D G+ C + S CV + C+ Y Sbjct: 1757 NYSCACVSGFTGRNCEIDID------DCVGNNCTNNSTCVDLIDD----YNCTCQVGYNG 1806 Query: 1101 AVCEL 1105 + CEL Sbjct: 1807 SYCEL 1811 Score = 33.5 bits (73), Expect = 2.5 Identities = 14/49 (28%), Positives = 22/49 (44%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRF 1358 C C + PC + C++ +Y C CK+G+ G C + RF Sbjct: 1809 CELDIDECLANPCSSYGSCNNTIGSYECVCKQGYYGNHCQYNASQWCRF 1857 Score = 33.1 bits (72), Expect = 3.3 Identities = 29/108 (26%), Positives = 40/108 (37%), Gaps = 15/108 (13%) Query: 1465 IGGLDTTAGLLASDVGF---FEGCIQDVRIGT--------AQSLLNRPT--VRENVRDGC 1511 +GGL+ DV GCI D R+ + + S + P + N+ GC Sbjct: 1289 LGGLENWTAYQQEDVVTKIPLRGCIHDARLNSKLLQFFPVSSSEESFPLLGIASNLGRGC 1348 Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC-VSACEL-GPC 1557 C S C C W+ C+C GP C + C L PC Sbjct: 1349 LGENVCARSPCGMGGTCNDRWNKYECSCSPRYGGPDCSLYGCALVKPC 1396 Score = 33.1 bits (72), Expect = 3.3 Identities = 48/204 (23%), Positives = 63/204 (30%), Gaps = 26/204 (12%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC----VSACEL-GPC-GAARCVPDQTPK 1569 +C+ + C Y C + S C C+ G G C C PC A C + T Sbjct: 1815 ECLANPCSSYGSCNNTIGSYECVCKQGYYGNHCQYNASQWCRFQQPCMNNATCSGNAT-- 1872 Query: 1570 GYSCACEPGY--TLTTSGCIESGKEECPGGW-----WGGSACGP---CACDVTRGYHPHC 1619 G+ C C G+ L + E C S P CAC V P C Sbjct: 1873 GFYCTCAEGWEGKLCSVDIKECESTPCQNNGTCTDSHSVSEFFPGYRCACTVDY-TGPSC 1931 Query: 1620 NKENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676 K C C N + C C G N +C C P + G Sbjct: 1932 EKLVTPCDEKPCLNNGSCIRLSYNKYECNC-TEGYGNMNCSGLLSYCTPNPCINGNCIPL 1990 Query: 1677 CANAYAEVTP---NSGCEVVYDGC 1697 N E C+++ D C Sbjct: 1991 MDNYICECDSKYLGRNCDILRDKC 2014 Score = 32.7 bits (71), Expect = 4.4 Identities = 12/36 (33%), Positives = 18/36 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C+S+PC N C D + C C +G G C + + Sbjct: 544 CNSSPCLNNGTCVDDVGFFNCTCPKGFDGVRCENKS 579 Score = 32.3 bits (70), Expect = 5.8 Identities = 13/29 (44%), Positives = 15/29 (51%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 PC N A CS + C C EG GK C+ Sbjct: 1860 PCMNNATCSGNATGFYCTCAEGWEGKLCS 1888 >SB_16968| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 1101 Score = 70.9 bits (166), Expect = 1e-11 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 12/96 (12%) Query: 1607 CACDVTRGY-HPHCNKENGKCHCKE-------NHYKPE----GTAECLPCQCYAAGSENS 1654 C CD Y + C++ GKC CK + KP ++ C PC C + GS + Sbjct: 729 CGCDSVGTYLNSTCDRYGGKCQCKPGVTGRTCDKCKPGFYNFTSSGCAPCDCVSTGSHHL 788 Query: 1655 SCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 C A +GQC C+PGVI R C C +++ T SGC Sbjct: 789 VCNAVSGQCPCKPGVITRTCSRCNDSFYGYTTGSGC 824 Score = 70.9 bits (166), Expect = 1e-11 Identities = 52/203 (25%), Positives = 76/203 (37%), Gaps = 23/203 (11%) Query: 1510 GCQSRADCMLSICPPYS-KCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQ-- 1566 GC S + S C Y KC + TC+ + G ++ PC Sbjct: 730 GCDSVGTYLNSTCDRYGGKCQCKPGVTGRTCDKCKPGFYNFTSSGCAPCDCVSTGSHHLV 789 Query: 1567 -TPKGYSCACEPGY-TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG 1624 C C+PG T T S C +S G+ GS C C C+++ C+ G Sbjct: 790 CNAVSGQCPCKPGVITRTCSRCNDSFY-----GYTTGSGCVECRCNMSGSADAQCDDVTG 844 Query: 1625 KCHCKENH-----------YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRA 1673 C CK + + +A C C C+ GS++ C TG C C+ +G Sbjct: 845 NCTCKNSTDGAKCAECRFGFYNFTSAGCQACNCHEGGSQSQQCNLQTGICTCKSNALGEK 904 Query: 1674 CDACANAYAEVTPNS--GCEVVY 1694 C++C PN+ GC Y Sbjct: 905 CESCRPGTYHSDPNNPDGCTPCY 927 Score = 52.4 bits (120), Expect = 5e-06 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 7/69 (10%) Query: 1620 NKENGKCH-CKENHYKPEGTAE-----CLPCQCYAAG-SENSSCEAATGQCHCRPGVIGR 1672 N E C CK+ Y+ + C C C+ G + N +C TGQC CR V GR Sbjct: 347 NTEGHFCERCKDKFYRNMSLSLNHPEICPDCNCFPQGITNNGTCNQTTGQCECRANVTGR 406 Query: 1673 ACDACANAY 1681 CD+CA+ + Sbjct: 407 QCDSCADTF 415 Score = 46.8 bits (106), Expect = 3e-04 Identities = 36/146 (24%), Positives = 50/146 (34%), Gaps = 21/146 (14%) Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSA-----CGPCAC-- 1609 C C P +C G + + C +WG + C C C Sbjct: 374 CPDCNCFPQGITNNGTCNQTTGQCECRANVTGRQCDSCADTFWGYTLEPIGYCTECLCVG 433 Query: 1610 DVTRGYHPHCNKENGKCHCKEN-HYK------------PEGT-AECLPCQCYAAGSENSS 1655 + T +C++ NG+C CK N H + P+ +C C C GS Sbjct: 434 NGTVNASLNCDQYNGQCSCKPNVHTRTCQECKHGYWDFPKTLDTDCKRCDCDYGGSVLQI 493 Query: 1656 CEAATGQCHCRPGVIGRACDACANAY 1681 C TG C CR +IG C Y Sbjct: 494 CNKTTGSCMCRTNIIGTRCTDVTTGY 519 Score = 34.7 bits (76), Expect = 1.1 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 19/85 (22%) Query: 1593 ECPGGWWGGSACGPCACDVTRG--YHPHCNKENGKCHCKEN--------------HYKPE 1636 EC G++ ++ G AC+ G CN + G C CK N H P Sbjct: 859 ECRFGFYNFTSAGCQACNCHEGGSQSQQCNLQTGICTCKSNALGEKCESCRPGTYHSDPN 918 Query: 1637 GTAECLPCQCYAAGSENSSCEAATG 1661 C PC C+ +++C +A+G Sbjct: 919 NPDGCTPCYCF---GRSNTCTSASG 940 >SB_35857| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2680 Score = 70.5 bits (165), Expect = 2e-11 Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 20/161 (12%) Query: 1546 PQCVSACELGPCGAARCVPDQTPKG-YSCACEPGYTLTTSGCIESGKEECPGGWW---GG 1601 P+ AC P G D+TP G C+ G + ++C ++ G Sbjct: 762 PEGCQACNCNPKGTLG--GDRTPAGELECSGSNGKCACLTNVQGLRCDQCVSAYYWNPSG 819 Query: 1602 SACGPCACDVTRGYHPHCNKENGKCHCKEN-------HYKPE---GTAECLPCQCYAAGS 1651 C PC CD + +CN G C CK N P G C PC C AGS Sbjct: 820 YGCSPCNCDASGSLATNCNS-TGYCQCKPNIGGRRCDRCMPGSYGGPGSCKPCNCNMAGS 878 Query: 1652 ENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNS--GC 1690 + +C+ + G+C+C+P V G CD C + + N+ GC Sbjct: 879 LSDTCDDS-GKCNCKPNVQGDKCDTCKDGTQNLQVNNDFGC 918 Score = 60.1 bits (139), Expect = 3e-08 Identities = 51/166 (30%), Positives = 68/166 (40%), Gaps = 25/166 (15%) Query: 1517 CMLSICPPY----SKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYS 1572 C L C P S S CTC+ P C C G + P+ + Sbjct: 712 CSLCSCDPKGIQGSSLTCEVSSGNCTCKKYVREPTC-GQCMKGYFNLSSSNPEGCQ---A 767 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632 C C P TL +G+ EC G + G CAC +T C++ C + Sbjct: 768 CNCNPKGTLGGDRT-PAGELECSG------SNGKCAC-LTNVQGLRCDQ------CVSAY 813 Query: 1633 Y-KPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC 1677 Y P G C PC C A+GS ++C + TG C C+P + GR CD C Sbjct: 814 YWNPSGYG-CSPCNCDASGSLATNCNS-TGYCQCKPNIGGRRCDRC 857 Score = 58.0 bits (134), Expect = 1e-07 Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 16/112 (14%) Query: 1587 IESGKEECP-GGWWGGSACGPCAC-DVTRGYHPHCNKENGKCHCKENHY--KPEGTAECL 1642 +E+GK C G G C C T+G C+ CK Y K + C+ Sbjct: 506 VETGKTSCARDDSTPGVIAGQCECKQYTQGRQ--CDA------CKPGFYDLKSSHSTGCV 557 Query: 1643 PCQCYAAGS--ENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPN--SGC 1690 C C AG+ N+SC+ + GQC+C+ V GR CD C + + + N SGC Sbjct: 558 TCGCNTAGTVNRNASCDQSRGQCYCKSNVTGRTCDTCESGFYGLRDNDPSGC 609 Score = 56.0 bits (129), Expect = 4e-07 Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 33/162 (20%) Query: 1537 CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGY-SCACEPGYTLTTSGCIESGKEECP 1595 C C++ G C CE G G + D P G +C C+P TL S C ++G Sbjct: 580 CYCKSNVTGRTC-DTCESGFYG----LRDNDPSGCRACECDPFGTLPGSVC-DAGS---- 629 Query: 1596 GGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN-- 1653 G C C +CH E+ Y ++ C C C G++ Sbjct: 630 ---------GQCRCKA--------GSTGLRCHLCEDGYHSLDSSGCKTCNCSTIGAKPGL 672 Query: 1654 -SSCEAATGQCHCRPGVIGRACDACANAYAEVTP--NSGCEV 1692 ++C+ GQC+C+ V G+ CD C Y +T GC + Sbjct: 673 VNTCDKTNGQCYCKTYVEGKTCDRCKTGYYNLTTVNQDGCSL 714 Score = 46.0 bits (104), Expect = 4e-04 Identities = 54/226 (23%), Positives = 74/226 (32%), Gaps = 42/226 (18%) Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG------- 1555 +R+N GC++ +C P S C S C C+AG G +C CE G Sbjct: 601 LRDNDPSGCRA-CECDPFGTLPGSVCDAG--SGQCRCKAGSTGLRC-HLCEDGYHSLDSS 656 Query: 1556 PCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGK--EECPGGWWG-----GSACGPCA 1608 C C G C+ GK + C G++ C C+ Sbjct: 657 GCKTCNCSTIGAKPGLVNTCDKTNGQCYCKTYVEGKTCDRCKTGYYNLTTVNQDGCSLCS 716 Query: 1609 CDVT--RGYHPHCNKENGKCHCKENHYKP--------------EGTAECLPCQCYAAGSE 1652 CD +G C +G C CK+ +P C C C G+ Sbjct: 717 CDPKGIQGSSLTCEVSSGNCTCKKYVREPTCGQCMKGYFNLSSSNPEGCQACNCNPKGTL 776 Query: 1653 NSS--------CEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 C + G+C C V G CD C +AY GC Sbjct: 777 GGDRTPAGELECSGSNGKCACLTNVQGLRCDQCVSAYYWNPSGYGC 822 Score = 43.2 bits (97), Expect = 0.003 Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 15/87 (17%) Query: 1626 CH-CKENHYKPEGTA-----ECLPCQCYAAGSENSSCEAA---------TGQCHCRPGVI 1670 CH C+++ ++ G + C PCQC G E A GQC C+ Sbjct: 475 CHVCRDDFFREPGKSLSAVDVCSPCQCTGPGVETGKTSCARDDSTPGVIAGQCECKQYTQ 534 Query: 1671 GRACDACANAYAEVTPNSGCEVVYDGC 1697 GR CDAC + ++ + V GC Sbjct: 535 GRQCDACKPGFYDLKSSHSTGCVTCGC 561 Score = 37.5 bits (83), Expect = 0.15 Identities = 37/118 (31%), Positives = 52/118 (44%), Gaps = 11/118 (9%) Query: 1418 LSDGAWHRIEIKWLGT-DISVTVDYGLRTVLMPMLANKIQGQ-YIGKILIGGLDTTAGLL 1475 L DG WHR+EI +G TVD G++ V + + YIG I + + A Sbjct: 1608 LCDGFWHRVEITGVGNFSFVFTVD-GVKNVETAVDKIAVTSPLYIGGIPLDNNNAVAAAN 1666 Query: 1476 ASDVGF---FEGCIQDVRIGTAQSLLNRP--TVRENVRDGCQSRADCMLSICPPYSKC 1528 + + F GCI+DV T L R +R + DGC S L++ P S C Sbjct: 1667 KAGLDIQDTFGGCIRDVTTDT-NVLFGREVLAMRNSDLDGCVSNK--TLNVTQPSSAC 1721 Score = 32.3 bits (70), Expect = 5.8 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 9/106 (8%) Query: 1110 FPVSSFLTFPGLKRRHRI--HLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRG 1167 FP + + FPG R ++L F TQ GL+L+ ++ D LA+ L R Sbjct: 1339 FPGNGYYKFPGSYVREGTTNEIELWFRTQYPDGLILFLSDSSQA-DLLAVVL------RE 1391 Query: 1168 GGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILD 1213 G P F G ++ D WH +++ + T+ +D Sbjct: 1392 GKPWFIFDCQTGPAAFTVSAAVTFDDNQWHRLQLTRKDSVGTLTVD 1437 >SB_35310| Best HMM Match : Cadherin (HMM E-Value=5.9e-23) Length = 1250 Score = 70.5 bits (165), Expect = 2e-11 Identities = 165/757 (21%), Positives = 289/757 (38%), Gaps = 72/757 (9%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 SL+ +VA + ++ATD +P R V I+D ND S +TV+ + + Sbjct: 269 SLNNGEVA---ITIRATDNGNPPMWREQE---FKVRILDVNDPPGNISLSNHTVNKNAQV 322 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 V I D +S + + + + F ++ ++ + K L+ Sbjct: 323 GSLVG-VFTAIDGDDPTATPSSNFTWELTNSSNGL-FKLNG--SNLVVAKPLNNVPQNQI 378 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVND-NAPRFYTSL-FQESVSENVPIG-YSIVRVQ 280 ++ ++ D G P + T + +I + +D +A Y + +E S G + + Sbjct: 379 QIEVKCTDSGQPFENATQKFVIYLIMYDDYHASITYRPISVKEDASVGTTAGTLTATQSL 438 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS--GWVYTSGQLDRETQAKYQLLVTA 338 A +N L T+ +K G IT D + + +LD E ++ + +A Sbjct: 439 ALPVTLSIN-HLNNTVLEKFKIGATTCSITADTATCTADILVKSELDFEDKSTFTFTASA 497 Query: 339 T-DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397 G R T T ++ G V E+ G V + TD D+ Sbjct: 498 NFSKGVVTREFTITVKNVNEAPTDI---YLNGTLTVP--ENAVAGAIVGSFLVTDPDKTQ 552 Query: 398 RLHYE-ITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMV 455 + + + G T +NG L +P +++++ R + V+ TD G + + Sbjct: 553 THNCSLVNSAQSTGSSYFTVENGTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNLSTTK 612 Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 NIT N P + + + +V E++P+GT V +S + D N T+++ S+ Sbjct: 613 DFNITVTNQNEPPLQVSITSQTVPENSPLGTLVGSLSCEEPDKLTNDNCTFTIDSQ---- 668 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 + F + ++ N LD E + V A D G L ++I++ D N Sbjct: 669 -----NYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKG--GLYKKVKLQINITDQN 721 Query: 576 D-----NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 D N P L ++ E++ GT +S + D D L + G Sbjct: 722 DAPTGINLPGNGGDL---SVYENSRSGTVISAIKLVDQD---GDPPSCSLTD---DAGGR 772 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 V + +I + D E A + DG QS +I ++D+N+ P + Sbjct: 773 VAVQGTNLITGSANSDFEESAVLHITLSCSDGKV--QSIQKSFNITVKDVNEVPT--DIT 828 Query: 691 CLTFYISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIKGG--DDSNSFSLETRQGSDKA 746 + EN T IG I DPD + V I G D S F ++ ++ Sbjct: 829 LSHRQVLENE-ANTRIGIITVTDPDVNQSHRCTVCDVIDEGRCDASADFIVD-----ERL 882 Query: 747 ELVTMVDLDYESPRKKYELVI----RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 +L+T LD+ES + +VI A SP + V +T ++ N P F Sbjct: 883 QLLTSRGLDFESGHIR-RIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFE 941 Query: 803 NYKDCFPVGPFGRVPAYDAD----VTDKLQYRILSGN 835 R+ A D D V L Y+I++G+ Sbjct: 942 QAIRASVGSVVARLSAVDPDNAGSVKQALTYKIITGS 978 Score = 39.5 bits (88), Expect = 0.038 Identities = 48/197 (24%), Positives = 84/197 (42%), Gaps = 12/197 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D R LLT LD E +++ TD A+ LS ++ +ID N+ P Sbjct: 876 FIVDERL-QLLTSRGLDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNE--PP 932 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGA-NSAIRYAIIGGNTQMQFSIDSLSG 207 S + ++ I + V+A++ A D D G+ A+ Y II G+ F + Sbjct: 933 TS--VCSSPFEQAIRASVGSVVARLSAVDPDNAGSVKQALTYKIITGSGVFPFQLFK--- 987 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 + KT D Q ++ I+ D G + + L N+ N ++ + + Sbjct: 988 -NMIFKTADVIQPTNFTFSIQVTDDGRVVTDVSPNGLTFNVSKPNTVVFNCSLAVTADFM 1046 Query: 267 SENVPIGYSIVRVQAYD 283 S+ + + S+V VQ+ D Sbjct: 1047 SDALDLRPSVVSVQSRD 1063 Score = 38.3 bits (85), Expect = 0.088 Identities = 112/528 (21%), Positives = 184/528 (34%), Gaps = 41/528 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FR+ ++L SLD E ++V ATD+ L + +NI D ND Sbjct: 672 FRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGG-----LYKKVKLQINITDQNDAPTG 726 Query: 150 FSEKTYTVSVDEDISVTDN----PVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 + D+SV +N VI+ IK D D S GG +Q + + Sbjct: 727 IN----LPGNGGDLSVYENSRSGTVISAIKLVDQDGDPPSCSLTDDAGGRVAVQ-GTNLI 781 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 +G + D+E+ + + DG S + I ++DVN+ P T ++ Sbjct: 782 TGSAN----SDFEESAVLHITLSCSDGKVQSIQKSFN--ITVKDVNE-VPTDITLSHRQV 834 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--LPITIDPRSGWVYTSGQ 323 + I+ V D VN T+ D G D +D R + TS Sbjct: 835 LENEANTRIGIITV----TDPDVNQSHRCTVCDVIDEGRCDASADFIVDERL-QLLTSRG 889 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAEDEPPG 382 LD E+ ++++ TD P+ + E A G Sbjct: 890 LDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFEQAIRASVG 949 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + V L+A D D + +T G Q + +I + D Q + ++ Sbjct: 950 SVVARLSAVDPDNAGSVKQALTYKIITGSGVFPFQLFKNMI--FKTADVIQPTNFTFSIQ 1007 Query: 443 ATDSGG-RSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 TD G +D + + + VF + TA DA + VVS D + Sbjct: 1008 VTDDGRVVTDVSPNGLTFNVSKPNTVVFNCSLAVTADFMSDA-LDLRPSVVSVQSRDNSL 1066 Query: 501 NAQITYSLSSEISNEA---VAHHDQ--QFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 ++ SL + NE + + D+ F IN + + + D + D Sbjct: 1067 IGRL--SLPKKFPNETFKYLLNSDETVPFAINGDQVFVKSIAMKDYALIFENKSAFVYLD 1124 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 S E V ++D+ P K L +I E G+ V Q+ Sbjct: 1125 INAESSQGVNRSEGHFVKISDDVPEMKMCLVKKSIEEKKPQGSIVGQL 1172 >SB_35194| Best HMM Match : EGF_2 (HMM E-Value=0) Length = 960 Score = 70.1 bits (164), Expect = 2e-11 Identities = 70/249 (28%), Positives = 91/249 (36%), Gaps = 28/249 (11%) Query: 1494 AQSLLNRPTVRENVRD-GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS-A 1551 A S L PT + + D C S A C P S + +S C C G G C Sbjct: 79 AASGLELPTRKPCIGDRNCGSNAACH----PNQSGRIEKKES--CYCLPGYHGDGCQHYG 132 Query: 1552 CELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACD 1610 C PC C + CAC PG+ T C + CP G WG G C C Sbjct: 133 CTPNPCQNGGTCKQSLQNGSFVCACAPGFHGNT--C----QLPCPDGQWGIDCKGVCTCS 186 Query: 1611 VTRGYHPHCNKENGKCHCKENHYKPEGTAEC------LPCQCYAAGSENSSCEAATGQCH 1664 + C+ GKCHC + P EC C +SC+ TG C+ Sbjct: 187 E----YGSCDSRTGKCHCMPGYSGPTCIDECPTGYYGYECTQKCQCVNGASCDRRTGSCN 242 Query: 1665 CRPGVIGRAC-DACA-NAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDC-P 1721 C G IG+ C C N + E C G S+ + +T + + DC Sbjct: 243 CTVGWIGKFCQQTCPHNTWGEGYCKEECPRGIYGRNCSYTCQCAYNQTCSKRDGLCDCRV 302 Query: 1722 PGSSGRATR 1730 PG +G R Sbjct: 303 PGVTGVTCR 311 Score = 68.1 bits (159), Expect = 9e-11 Identities = 55/179 (30%), Positives = 76/179 (42%), Gaps = 33/179 (18%) Query: 1520 SICPP--YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGY------ 1571 S CP +S + + C C G G C+ AC +G G Q GY Sbjct: 541 SPCPKCYHSNGACNAATGKCVCLDGYHGDSCLEACSVGYFGRQCQSKCQCLHGYCDHVTG 600 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631 SC C PG+T C ++ CP G +G + PCAC + CN +G C+C Sbjct: 601 SCECLPGWT--GKRCDQA----CPSGTYGFNCTLPCAC-----VNGSCNATDGSCNCAAG 649 Query: 1632 HYK-------PEGT--AEC-LPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 ++ P G A C L C C + N +C A TG+C C G G +C+A +A Sbjct: 650 YHGNACDRPCPAGKHGANCGLKCLC----ANNGTCNAITGRCSCGTGWTGPSCNASCSA 704 Score = 63.7 bits (148), Expect = 2e-09 Identities = 47/194 (24%), Positives = 62/194 (31%), Gaps = 24/194 (12%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTL 1581 CP + S C+C G GP C C G P G C G Sbjct: 327 CPCMNGAECDRVSGVCSCSPGWTGPFCSKPCPPSLWGHNCAHPCNCTNGARCNAVTGQCA 386 Query: 1582 TTSGCIESGKEECPGGWWGGSACGPCACD---------VTRGYHPHCNKENGKCHCKENH 1632 T GC C GW G PC D + C+ +G+C C Sbjct: 387 CTDGC------SCNAGWTGPECRDPCGLDSWGPGCTNTCQCSRNGECDAASGRCACAPGF 440 Query: 1633 YKPEGTAEC------LPCQ--CYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAE 1683 + C C C + + C+ +G CHC PG GR+C C Sbjct: 441 TGDRCESRCPKGYYGTNCSNACTCKATNTNVCDVTSGFCHCNPGWSGRSCYQPCPGGSWG 500 Query: 1684 VTPNSGCEVVYDGC 1697 V +S C+ + C Sbjct: 501 VNCSSKCDCINGSC 514 Score = 62.9 bits (146), Expect = 4e-09 Identities = 54/166 (32%), Positives = 69/166 (41%), Gaps = 31/166 (18%) Query: 1539 CEAGRVGPQCVSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597 C AG G C C PC A C D+ G C+C PG+T G S + CP Sbjct: 314 CRAGFFGIDCNHKC---PCMNGAEC--DRV-SGV-CSCSPGWT----GPFCS--KPCPPS 360 Query: 1598 WWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTA--ECL-PCQCYAAG---- 1650 WG + PC C T G CN G+C C + G EC PC + G Sbjct: 361 LWGHNCAHPCNC--TNG--ARCNAVTGQCACTDGCSCNAGWTGPECRDPCGLDSWGPGCT 416 Query: 1651 -----SENSSCEAATGQCHCRPGVIGRACDA-CANAYAEVTPNSGC 1690 S N C+AA+G+C C PG G C++ C Y ++ C Sbjct: 417 NTCQCSRNGECDAASGRCACAPGFTGDRCESRCPKGYYGTNCSNAC 462 Score = 60.9 bits (141), Expect = 1e-08 Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 26/166 (15%) Query: 1537 CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPG 1596 C+C G GP C ++C G G +C PG+T G +S K+ CP Sbjct: 687 CSCGTGWTGPSCNASCSAGRYGI------------NCVARPGWT----G--KSCKDPCPA 728 Query: 1597 GWWGGSACGPCACDVTR-GYHPHCNKENGKCHCKENHYKPEGTAECLP------CQCYAA 1649 G +G C CD ++ C+ G+C+C+ + P +C C Sbjct: 729 GRYGMMCASSCRCDPSKTDVKKPCDHVTGQCNCRPGYRGPRCLEQCPEGRYGDQCARKCE 788 Query: 1650 GSENSSCEAATGQCHCRPGVIGRACD-ACANAYAEVTPNSGCEVVY 1694 C A G C C PG G +C C +S C+ V+ Sbjct: 789 CDNRVPCRATDGVCLCLPGYYGNSCQLMCPRDRYGFNCSSTCQCVH 834 Score = 56.8 bits (131), Expect = 2e-07 Identities = 48/178 (26%), Positives = 63/178 (35%), Gaps = 37/178 (20%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570 C S+ DC+ C P + C C G +C C +C Sbjct: 503 CSSKCDCINGSCDPVT--------GACVCNRRVTGQRCDKPCINCNSPCPKCYHSNGACN 554 Query: 1571 YS---CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627 + C C GY C+E+ C G++G C C H +C+ G C Sbjct: 555 AATGKCVCLDGYH--GDSCLEA----CSVGYFGRQCQSKCQC-----LHGYCDHVTGSCE 603 Query: 1628 C-------KENHYKPEGTA--EC-LPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 C + + P GT C LPC C N SC A G C+C G G ACD Sbjct: 604 CLPGWTGKRCDQACPSGTYGFNCTLPCACV-----NGSCNATDGSCNCAAGYHGNACD 656 Score = 51.6 bits (118), Expect = 9e-06 Identities = 47/190 (24%), Positives = 66/190 (34%), Gaps = 29/190 (15%) Query: 1511 CQSRADCMLSICPPYS---KCVTSWDSSTC--TCEAGRVGPQCV--SACELGPC----GA 1559 CQS+ C+ C + +C+ W C C +G G C AC G C G+ Sbjct: 584 CQSKCQCLHGYCDHVTGSCECLPGWTGKRCDQACPSGTYGFNCTLPCACVNGSCNATDGS 643 Query: 1560 ARCVPDQTPKGYSCACEPGYTLTTSG----CIESG-------KEECPGGWWGGSACGPCA 1608 C C G G C +G + C GW G S C+ Sbjct: 644 CNCAAGYHGNACDRPCPAGKHGANCGLKCLCANNGTCNAITGRCSCGTGWTGPSCNASCS 703 Query: 1609 CD---VTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSE-NSSCEAATGQCH 1664 + P ++ K C Y G C+C + ++ C+ TGQC+ Sbjct: 704 AGRYGINCVARPGWTGKSCKDPCPAGRY---GMMCASSCRCDPSKTDVKKPCDHVTGQCN 760 Query: 1665 CRPGVIGRAC 1674 CRPG G C Sbjct: 761 CRPGYRGPRC 770 Score = 48.8 bits (111), Expect = 6e-05 Identities = 45/150 (30%), Positives = 60/150 (40%), Gaps = 23/150 (15%) Query: 1537 CTCEAGRVGPQCVSACELGPCG---AARC-----VPDQTPKGYSCACEPGYTLTTSGCIE 1588 C C G GP+C+ C G G A +C VP + G C C PGY + C Sbjct: 759 CNCRPGYRGPRCLEQCPEGRYGDQCARKCECDNRVPCRATDGV-CLCLPGYY--GNSC-- 813 Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK---CHCKENHYKPEGTAECLPCQ 1645 + CP +G + C C G C+K++G C EN P+GT C Sbjct: 814 --QLMCPRDRYGFNCSSTCQC--VHGNTRMCDKKDGSYVGVLC-ENRC-PQGTYGP-GCH 866 Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 + C+ TG C C G G+ CD Sbjct: 867 NNCTCLNGAQCDHVTGTCTCPVGYKGKYCD 896 Score = 37.5 bits (83), Expect = 0.15 Identities = 42/168 (25%), Positives = 57/168 (33%), Gaps = 22/168 (13%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCT--CEAGRVGPQCVSACELGPCGAARCVPDQTP 1568 C +R C + C+ + ++C C R G C S C+ C D+ Sbjct: 789 CDNRVPCRAT--DGVCLCLPGYYGNSCQLMCPRDRYGFNCSSTCQCVHGNTRMC--DKKD 844 Query: 1569 KGY-SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKC 1626 Y CE T G C G G C C V GY +C+ Sbjct: 845 GSYVGVLCENRCPQGTYGPGCHNNCTCLNGAQCDHVTGTCTCPV--GYKGKYCD-----V 897 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C + + P T CL C+ + C+ TG C C PG G C Sbjct: 898 ICDKGTFGPGCTQRCL-CE------NGAKCDRKTGACTCAPGFEGLRC 938 Score = 33.1 bits (72), Expect = 3.3 Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 2/34 (5%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 PC NGAEC + + +C C G TG C+ P Sbjct: 328 PCMNGAECDRV--SGVCSCSPGWTGPFCSKPCPP 359 >SB_6200| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 683 Score = 70.1 bits (164), Expect = 2e-11 Identities = 54/174 (31%), Positives = 74/174 (42%), Gaps = 31/174 (17%) Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGA-ARCVPDQTPKGYSCA-CEPG-YTLTTSGCIE-- 1588 + T C +G + +S CE P G RC P +G C C+PG Y +T+ GC Sbjct: 23 NGTLPCSCDPLGSRTLSECE--PYGGQCRCKPGV--EGRDCGRCKPGFYNMTSEGCRPCD 78 Query: 1589 -----------SGKEECPGGWWGGSACGPCACD------VTRGYHPHCNKENGKCHCKEN 1631 SG+ ECP G + C PC C+ + G C +C + Sbjct: 79 CKGPNSVCDPVSGECECPANTVGRT-CEPCQCNNSTDKCLRSGECRDCQHNTTGFYCDKC 137 Query: 1632 HYKPEGTA---ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC-ANAY 1681 G A +C C C GS +S C+ TGQC C+ V+GR C C N+Y Sbjct: 138 VTGTYGNATAQQCKACDCNVNGSSSSLCDHVTGQCSCKENVVGRDCSRCKVNSY 191 Score = 55.2 bits (127), Expect = 7e-07 Identities = 44/122 (36%), Positives = 57/122 (46%), Gaps = 20/122 (16%) Query: 1599 WGGSACGPCACDV---------TRGYHPHCNKE--NGKC-HCKENHYK-PEGTAECLPCQ 1645 +G + C CAC+V G P CN E KC CK ++ P+ T C C Sbjct: 193 FGPAGCTECACNVHGSASLQCDDSGVCP-CNLEVIGTKCAQCKTGYFGLPKMT--CKACD 249 Query: 1646 CYAAGSENSS-CEAAT-GQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAG 1703 C G+ N + C T GQC C+ GV GRACD C + T +SGC V GC ++ Sbjct: 250 CNVDGTVNGTVCANDTIGQCQCKSGVTGRACDKCQIYFTGFT-SSGC-VACPGCVKALMK 307 Query: 1704 GV 1705 V Sbjct: 308 NV 309 Score = 50.4 bits (115), Expect = 2e-05 Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 2/50 (4%) Query: 1642 LPCQCYAAGSEN-SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 LPC C GS S CE GQC C+PGV GR C C + +T + GC Sbjct: 26 LPCSCDPLGSRTLSECEPYGGQCRCKPGVEGRDCGRCKPGFYNMT-SEGC 74 >SB_10656| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1931 Score = 68.1 bits (159), Expect = 9e-11 Identities = 53/170 (31%), Positives = 68/170 (40%), Gaps = 21/170 (12%) Query: 1537 CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPG 1596 C C +G QC + C+ G G C Q C E G + E C Sbjct: 658 CQCRPYVIGRQC-NRCKTGYYGFPNCKKCQC---VFCNEETGACDCPPNTVGLNCELCLK 713 Query: 1597 GWWGGS---ACGPCACDV--TRGYHPHCNKENGKCHCKENHYKPE---------GTAECL 1642 G +G + C C CD G + CN + G+C CK +H G C Sbjct: 714 GTFGYNPILGCQDCKCDRFGVAGGNIACNPKTGQCPCKPSHTGRRCDQCAVGYHGYPYCQ 773 Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV--TPNSGC 1690 C C A G S C++ TG+C C+ GV G CD CA Y + T SGC Sbjct: 774 QCDCDARGVNGSVCDS-TGRCLCKAGVTGIRCDTCAAGYFNLDNTNPSGC 822 Score = 67.3 bits (157), Expect = 2e-10 Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 18/122 (14%) Query: 1592 EECPGGWWGGSA----CGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTA-------- 1639 E C G++G + C C C CN NG C CK N P + Sbjct: 1209 ERCRDGYYGDAVVAKNCAKCECSACGAVTSVCNHTNGACQCKANVIGPNCSTCKPNTWNF 1268 Query: 1640 -ECLPCQ-CYAA-GSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDG 1696 CL C+ C A S SC TGQC C+PG GR C+ C + N+GC+ Sbjct: 1269 NSCLGCEDCECAEASLGQSCNVRTGQCLCKPGATGRRCERCKAGFWNY-KNTGCQAC--N 1325 Query: 1697 CP 1698 CP Sbjct: 1326 CP 1327 Score = 55.2 bits (127), Expect = 7e-07 Identities = 66/232 (28%), Positives = 85/232 (36%), Gaps = 27/232 (11%) Query: 1516 DCMLSICPP-------YSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQT 1567 DC L CP S+C D S C C G G QC C G G VP Sbjct: 1090 DCQLCKCPLGTSSNSFASECNVRGDGSLECLCREGYTGDQC-EQCADGYYGDPS-VPGDY 1147 Query: 1568 PKGYSCA--CEPGYTLTTSGCIESGKE-ECPGGWWGGSACGPCACDVTRGYHPHC-NKEN 1623 K C +P +L I+ + E S P +C+ G C NK Sbjct: 1148 CKKCDCNGNIDPDISLDLKLDIDFSLDLELAIDL---SHQVPGSCNPFTGVCNRCTNKAA 1204 Query: 1624 G-KCH-CKENHYKPEGTAE-CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 G +C C++ +Y A+ C C+C A G+ S C G C C+ VIG C C Sbjct: 1205 GDRCERCRDGYYGDAVVAKNCAKCECSACGAVTSVCNHTNGACQCKANVIGPNCSTCKPN 1264 Query: 1681 YAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTC 1732 GCE C + G RT + C PG++GR C Sbjct: 1265 TWNFNSCLGCEDC--ECAEASLGQSCNVRTGQCL-----CKPGATGRRCERC 1309 Score = 54.4 bits (125), Expect = 1e-06 Identities = 41/140 (29%), Positives = 53/140 (37%), Gaps = 29/140 (20%) Query: 1557 CGAARCVPDQTPK-GYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615 C + D+ + G C C P Y + C C G++G C C C Sbjct: 641 CDTKGALSDECQEFGGQCQCRP-YVIGRQ-C-----NRCKTGYYGFPNCKKCQC------ 687 Query: 1616 HPHCNKENGKCHCKEN------HYKPEGT------AECLPCQC--YAAGSENSSCEAATG 1661 CN+E G C C N +GT C C+C + N +C TG Sbjct: 688 -VFCNEETGACDCPPNTVGLNCELCLKGTFGYNPILGCQDCKCDRFGVAGGNIACNPKTG 746 Query: 1662 QCHCRPGVIGRACDACANAY 1681 QC C+P GR CD CA Y Sbjct: 747 QCPCKPSHTGRRCDQCAVGY 766 Score = 53.2 bits (122), Expect = 3e-06 Identities = 21/53 (39%), Positives = 28/53 (52%) Query: 1642 LPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVY 1694 LPC+C G+ + C+ GQC CRP VIGR C+ C Y C+ V+ Sbjct: 637 LPCECDTKGALSDECQEFGGQCQCRPYVIGRQCNRCKTGYYGFPNCKKCQCVF 689 Score = 49.2 bits (112), Expect = 5e-05 Identities = 39/137 (28%), Positives = 46/137 (33%), Gaps = 22/137 (16%) Query: 1606 PCACDVTRGYHPHCNKENGKCHCKE-------NHYKPE--GTAECLPCQCYAAGSENSSC 1656 PC CD C + G+C C+ N K G C CQC C Sbjct: 638 PCECDTKGALSDECQEFGGQCQCRPYVIGRQCNRCKTGYYGFPNCKKCQCVF-------C 690 Query: 1657 EAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPR-SFAGGVWWPRTKFGVE 1715 TG C C P +G C+ C P GC+ C R AGG K G Sbjct: 691 NEETGACDCPPNTVGLNCELCLKGTFGYNPILGCQDC--KCDRFGVAGGNIACNPKTGQ- 747 Query: 1716 TITDCPPGSSGRATRTC 1732 C P +GR C Sbjct: 748 --CPCKPSHTGRRCDQC 762 Score = 45.2 bits (102), Expect = 8e-04 Identities = 17/34 (50%), Positives = 20/34 (58%) Query: 1641 CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C C C GS + C++ TGQC CRP V GR C Sbjct: 80 CSGCACDVGGSFDQKCDSITGQCKCRPNVRGRDC 113 Score = 44.8 bits (101), Expect = 0.001 Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 12/124 (9%) Query: 1515 ADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACE-----LGPC-GAARCVPDQTP 1568 A C S C + V + + C C+A +GP C S C+ C G C + Sbjct: 1226 AKCECSACGAVTS-VCNHTNGACQCKANVIGPNC-STCKPNTWNFNSCLGCEDCECAEAS 1283 Query: 1569 KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRG---YHPHCNKENGK 1625 G SC G L G E C G+W G AC+ G C+ G+ Sbjct: 1284 LGQSCNVRTGQCLCKPGATGRRCERCKAGFWNYKNTGCQACNCPGGPENLWGFCDVNTGQ 1343 Query: 1626 CHCK 1629 C CK Sbjct: 1344 C-CK 1346 Score = 33.5 bits (73), Expect = 2.5 Identities = 11/28 (39%), Positives = 15/28 (53%) Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKEN 1631 C CACDV + C+ G+C C+ N Sbjct: 80 CSGCACDVGGSFDQKCDSITGQCKCRPN 107 Score = 33.1 bits (72), Expect = 3.3 Identities = 13/54 (24%), Positives = 27/54 (50%), Gaps = 5/54 (9%) Query: 1622 ENGKC-HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRA 1673 + G C +C + + + C+PC+C ++ C+ TG+C +C+ G + Sbjct: 994 DGGSCEYCGKGFTRSDDERTCIPCRC---NGHSNECDPETGECINCQDNTAGNS 1044 >SB_30436| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 633 Score = 68.1 bits (159), Expect = 9e-11 Identities = 42/114 (36%), Positives = 63/114 (55%), Gaps = 9/114 (7%) Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 V A+D + + + ITD N+YAPVF+N P T S+ E+ P G TV +ATD+D Sbjct: 239 VYASDGSTQGSLTAI-LTITDVNDYAPVFQNLPLTTSIAENTPTGFTVATATATDADATT 297 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTA 553 NA IT++++S + D +F I+ TG IT K L+ + Y L ++A Sbjct: 298 NAVITFAVAS-------GNVDGKFRIDQTTGEITIAKPLEYDNGPKIYTLNISA 344 Score = 66.9 bits (156), Expect = 2e-10 Identities = 81/308 (26%), Positives = 130/308 (42%), Gaps = 35/308 (11%) Query: 488 VLVVSAT-DSDVGINA-QITYSLSSEISN-EAVAHHDQQFVINPQTGAITTNKLLDRETM 544 VL V+ T D +V I + +L E+S+ E + ++ G +T NK LDRE Sbjct: 46 VLTVNKTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVS--IGELTVNKTLDREVS 103 Query: 545 SGYLLTVTARDGGVPS----LSDTTDVEIS----VVDVNDNEPVFKQQLYTANIMEDALV 596 SG L+ D V S +S T D E+S +V + V +L + ++ + Sbjct: 104 SGELIVSKTLDREVSSEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASKTLDREVS 163 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKD------REEGSFVIDPASGVIRTNKALDRESV 650 ++ D +V I + +D E+ ID + ++ T L Sbjct: 164 SGELTVNKTLDREVSSEELIASKTLDRDASKRTEEEQKLLHIDKSYKIVATPSTLALVGT 223 Query: 651 ---------ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 + K A DG T Q S + + I D+ND PVF++ LT I+EN+P Sbjct: 224 IPLAMGFGDGSLRFKVYASDGST--QGSLTAI-LTITDVNDYAPVFQNLPLTTSIAENTP 280 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 G T+ A D D NAV+ +++ G+ F ++ G E+ L+Y++ K Sbjct: 281 TGFTVATATATDADATTNAVITFAVASGNVDGKFRIDQTTG----EITIAKPLEYDNGPK 336 Query: 762 KYELVIRA 769 Y L I A Sbjct: 337 IYTLNISA 344 Score = 64.9 bits (151), Expect = 9e-10 Identities = 65/251 (25%), Positives = 108/251 (43%), Gaps = 18/251 (7%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRL-SSTATIHVN---IIDDNDNYPQFS 151 SG L+ +LDRE + ++ K D+ + + S T V+ +I + S Sbjct: 104 SGELIVSKTLDREVSSEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASKTLDREVS 163 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 TV+ D V+ +IA K D D + ++ + + I + ++L Sbjct: 164 SGELTVNKTLDREVSSEELIAS-KTLDRDASKRTEEEQKLL--HIDKSYKIVATPSTLAL 220 Query: 212 VKTLDYEQV---RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 V T+ S R + A DG S + ++ I DVND AP F S++E Sbjct: 221 VGTIPLAMGFGDGSLRFKVYASDG---STQGSLTAILTITDVNDYAPVFQNLPLTTSIAE 277 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N P G+++ A DAD NA +T+ + +GNVD ID +G + + L+ + Sbjct: 278 NTPTGFTVATATATDADATTNAVITFAVA----SGNVDGKFRIDQTTGEITIAKPLEYDN 333 Query: 329 QAK-YQLLVTA 338 K Y L ++A Sbjct: 334 GPKIYTLNISA 344 Score = 49.6 bits (113), Expect = 4e-05 Identities = 81/339 (23%), Positives = 132/339 (38%), Gaps = 26/339 (7%) Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172 +T+ A P SS+ + VN D + E T ++D ++S + +++ Sbjct: 24 HTLTYSLQSNAHPWFRINSSSGVLTVNKTLDRE--VSIGELTVNKTLDREVS-SGELIVS 80 Query: 173 KIKATDADVG---ANSAIRYAIIGGNTQMQFSID-SLSGDVSLV-KTLDYEQVRSYRLVI 227 K + +G N + + G + ++D +S + +V KTLD E +V Sbjct: 81 KTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVSSEELIVSKTLDREVSNGELIVS 140 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287 + D S ++ R+V+ +L +E SE + ++ R DA + Sbjct: 141 KTLDREVSSGELIASKTLD-REVSSGELTVNKTLDREVSSEELIASKTLDR----DASKR 195 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347 E DK Y V P T+ G D + K V A+DG S Sbjct: 196 TEEEQKLLHIDKSYK-IVATPSTLALVGTIPLAMGFGDGSLRFK----VYASDGSTQG-S 249 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITG 405 TA +P +AE+ P G V T TATDAD + + + Sbjct: 250 LTAILTITDVNDYAPVFQNLP--LTTSIAENTPTGFTVATATATDADATTNAVITFAVAS 307 Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYVLTVSA 443 GN G+F I G IT+A+PL++ + Y L +SA Sbjct: 308 GNVDGKFRIDQTTGE--ITIAKPLEYDNGPKIYTLNISA 344 Score = 48.4 bits (110), Expect = 8e-05 Identities = 56/208 (26%), Positives = 91/208 (43%), Gaps = 29/208 (13%) Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GTT+ SAT+ D N +TYSL S AH F IN +G +T NK LDRE Sbjct: 10 GTTITKFSATNGD---NHTLTYSLQSN------AH--PWFRINSSSGVLTVNKTLDREVS 58 Query: 545 SGYLLTVTARDGGVPS----LSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDALV 596 G L D V S +S T D E+S+ ++ N+ + ++ +L + ++ + Sbjct: 59 IGELTVNKTLDREVSSGELIVSKTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVS 118 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI------DPASGVIRTNKALDRESV 650 + D +V I + ++ G + + +SG + NK LDRE V Sbjct: 119 SEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASKTLDREVSSGELTVNKTLDRE-V 177 Query: 651 ATHDL---KAVAIDGGTPPQSSTVIVHI 675 ++ +L K + D + ++HI Sbjct: 178 SSEELIASKTLDRDASKRTEEEQKLLHI 205 Score = 44.0 bits (99), Expect = 0.002 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 5/91 (5%) Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNAN 838 + +TDVND APV ++ + + + P G A DAD T + + + SGN Sbjct: 254 LTITDVNDYAPVFQNLPLT-TSIAENTPTGFTVATATATDADATTNAVITFAVASGNVDG 312 Query: 839 LILLNETTGSMTLSPQLN-TNVPKLATMEVS 868 +++TTG +T++ L N PK+ T+ +S Sbjct: 313 KFRIDQTTGEITIAKPLEYDNGPKIYTLNIS 343 Score = 41.9 bits (94), Expect = 0.007 Identities = 18/52 (34%), Positives = 28/52 (53%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 + + D ND++PVF+ S+ E +G TV T ATD D NA + + + Sbjct: 254 LTITDVNDYAPVFQNLPLTTSIAENTPTGFTVATATATDADATTNAVITFAV 305 Score = 33.9 bits (74), Expect = 1.9 Identities = 51/236 (21%), Positives = 97/236 (41%), Gaps = 16/236 (6%) Query: 90 FRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASP----VSDRLSSTATI-HVNIIDD 143 FRI+ SG L +LDRE + TV + S VS L +I + + Sbjct: 38 FRINSSSGVLTVNKTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVSIGELTVNKT 97 Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKI---KATDADVGANSAIRYAIIGGNTQMQF 200 D E + ++D ++S ++ +++K + ++ ++ + + + G Sbjct: 98 LDREVSSGELIVSKTLDREVS-SEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASK 156 Query: 201 SIDS--LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 ++D SG++++ KTLD E + + D + R+ Q L++I Sbjct: 157 TLDREVSSGELTVNKTLDREVSSEELIASKTLDRDASKRTEEEQKLLHIDKSYKIVATPS 216 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT--YTMTD-KDYTGNV-DLPIT 310 T ++ + G +R + Y +D LT T+TD DY +LP+T Sbjct: 217 TLALVGTIPLAMGFGDGSLRFKVYASDGSTQGSLTAILTITDVNDYAPVFQNLPLT 272 >SB_7853| Best HMM Match : Cadherin (HMM E-Value=9.9) Length = 114 Score = 67.7 bits (158), Expect = 1e-10 Identities = 42/116 (36%), Positives = 64/116 (55%), Gaps = 10/116 (8%) Query: 90 FRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 F I +SG + T +LDRE + + V A D+ + TI V ++D NDN P Sbjct: 6 FFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGGRTGE-----LTILVFLLDMNDNRP 60 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 +F++ Y V++ E T V+A + ATD D+G+N+ I Y I+GGN F+ID+ Sbjct: 61 RFTQSVYYVNITE----TTGHVMAGVSATDQDLGSNAVISYRILGGNIDDVFNIDN 112 Score = 62.9 bits (146), Expect = 4e-09 Identities = 40/99 (40%), Positives = 56/99 (56%), Gaps = 5/99 (5%) Query: 523 QFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 +F I+ Q+G I TT + LDRET + LTVTA D G + + + ++D+NDN P F Sbjct: 5 KFFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEG--GRTGELTILVFLLDMNDNRPRF 62 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 Q +Y NI E G ++ V ATD D+G N I Y + Sbjct: 63 TQSVYYVNITE--TTGHVMAGVSATDQDLGSNAVISYRI 99 Score = 60.9 bits (141), Expect = 1e-08 Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 3/99 (3%) Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469 G+F I++Q+G + T + LD + E + LTV+A D GGR+ + + + D N+ P F Sbjct: 4 GKFFISAQSGN-IYTTPENLDRETEDFFNLTVTAMDEGGRTGELTILVFLLDMNDNRPRF 62 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 + Y ++ E G + VSATD D+G NA I+Y + Sbjct: 63 TQSVYYVNITETT--GHVMAGVSATDQDLGSNAVISYRI 99 Score = 54.8 bits (126), Expect = 9e-07 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 628 GSFVIDPASGVIRTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 G F I SG I T + LDRE+ +L A+D G T++V + D+ND+ P Sbjct: 4 GKFFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGGRTGELTILVFLL--DMNDNRPR 61 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 F +Y++ G + + A D D G NAV+ Y I GG+ + F+++ Sbjct: 62 FTQS--VYYVNITETTGHVMAGVSATDQDLGSNAVISYRILGGNIDDVFNID 111 Score = 53.6 bits (123), Expect = 2e-06 Identities = 36/115 (31%), Positives = 60/115 (52%), Gaps = 9/115 (7%) Query: 199 QFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 +F I + SG++ + + LD E + L + A D G R+ +L+ + D+NDN PRF Sbjct: 5 KFFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGG--RTGELTILVFLLDMNDNRPRF 62 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 S++ +++E G+ + V A D D G NA ++Y + GN+D ID Sbjct: 63 TQSVYYVNITETT--GHVMAGVSATDQDLGSNAVISYRILG----GNIDDVFNID 111 Score = 39.9 bits (89), Expect = 0.029 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 +LD ND+ P F Y ++ E ++G + + ATDQD+G NA + Y I Sbjct: 52 LLDMNDNRPRFTQSVYYVNITE--TTGHVMAGVSATDQDLGSNAVISYRI 99 Score = 39.5 bits (88), Expect = 0.038 Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 3/105 (2%) Query: 311 IDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I +SG +YT+ + LDRET+ + L VTA D G R+ T F Sbjct: 8 ISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGG--RTGELTILVFLLDMNDNRPRFTQS 65 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414 Y V + E V+ T D + + Y I GGN F+I Sbjct: 66 VYYVNITETTGHVMAGVSATDQDLGSNAVISYRILGGNIDDVFNI 110 >SB_32515| Best HMM Match : FAINT (HMM E-Value=4.5) Length = 103 Score = 67.3 bits (157), Expect = 2e-10 Identities = 29/82 (35%), Positives = 47/82 (57%) Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 +D A + L A D G P +S+ VH+ ++DIND+ P+F +F + E++ + Sbjct: 18 IDNNGKAVYSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAH 77 Query: 705 TIGEIRAHDPDEGPNAVVHYSI 726 T+G++ A D D G NA + YSI Sbjct: 78 TVGKVTAEDKDWGINARLSYSI 99 Score = 66.9 bits (156), Expect = 2e-10 Identities = 35/100 (35%), Positives = 56/100 (56%), Gaps = 9/100 (9%) Query: 531 GAITTNKLLDRET---------MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 GA+T + L DRE + Y L V A D G P+++ + V + V D+NDN P+F Sbjct: 1 GALTWSNLFDREKPLLKIDNNGKAVYSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIF 60 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 + +Y+ + EDA + +V +V A D D G+N R+ Y ++ Sbjct: 61 SKTVYSFTVKEDAQLAHTVGKVTAEDKDWGINARLSYSIN 100 Score = 60.9 bits (141), Expect = 1e-08 Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 5/87 (5%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 +D A Y++LV+A D +P ++S+AT+HV + D NDN P FS+ Y+ +V ED Sbjct: 18 IDNNGKAVYSLLVEAADHGNPT---MTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQ 74 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAI 191 + + K+ A D D G N+ + Y+I Sbjct: 75 LAH--TVGKVTAEDKDWGINARLSYSI 99 Score = 58.8 bits (136), Expect = 6e-08 Identities = 23/74 (31%), Positives = 49/74 (66%) Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 Y L++ A D G+P+ +++ + + + D+NDN+P F +++ +V E+ + +++ +V A Sbjct: 26 YSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAE 85 Query: 283 DADEGVNAELTYTM 296 D D G+NA L+Y++ Sbjct: 86 DKDWGINARLSYSI 99 Score = 56.0 bits (129), Expect = 4e-07 Identities = 30/75 (40%), Positives = 45/75 (60%), Gaps = 2/75 (2%) Query: 437 YVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 Y L V A D G + T A V + + D N+ +P+F Y+ +V EDA + TV V+A Sbjct: 26 YSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAE 85 Query: 495 DSDVGINAQITYSLS 509 D D GINA+++YS++ Sbjct: 86 DKDWGINARLSYSIN 100 Score = 41.5 bits (93), Expect = 0.009 Identities = 20/48 (41%), Positives = 28/48 (58%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 D ND+SP+F Y +V+E A TV + A D+D G NA + Y+I Sbjct: 52 DINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAEDKDWGINARLSYSI 99 Score = 38.3 bits (85), Expect = 0.088 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 763 YELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 Y L++ AA +P + + V +LV D+NDN+P+ F +D G+V A Sbjct: 26 YSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAE 85 Query: 820 DAD--VTDKLQYRI 831 D D + +L Y I Sbjct: 86 DKDWGINARLSYSI 99 Score = 34.7 bits (76), Expect = 1.1 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 2/83 (2%) Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 ++D +A Y LLV A D G+P +++AT F Y + ED Sbjct: 17 KIDNNGKAVYSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLA 76 Query: 383 TPVVTLTATDAD--EDNRLHYEI 403 V +TA D D + RL Y I Sbjct: 77 HTVGKVTAEDKDWGINARLSYSI 99 >SB_29802| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 546 Score = 65.7 bits (153), Expect = 5e-10 Identities = 47/148 (31%), Positives = 65/148 (43%), Gaps = 22/148 (14%) Query: 1533 DSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592 ++ +C C+ G +C C G G C+ CAC T C + G+ Sbjct: 62 NTGSCVCKDNFQGHRC-QKCMTGYYGFPLCI--------KCACSNSGFGT---CGQYGEC 109 Query: 1593 ECPGGWWGGSACGPCACDVTRGYH--PHCNKENGKCHCKENHYKPEGTAECLPCQCYAAG 1650 C G+ G S C CA +G++ PHC E G EN + C C G Sbjct: 110 ICRPGYTGRS-CESCA----KGFYGFPHCTGEYG---LSENGIPVVNSITVATCNCNVQG 161 Query: 1651 SENSSCEAATGQCHCRPGVIGRACDACA 1678 SE+ SC+ A+G+C C+ VIG CD CA Sbjct: 162 SESQSCDQASGKCTCKKNVIGWKCDMCA 189 Score = 52.4 bits (120), Expect = 5e-06 Identities = 40/139 (28%), Positives = 54/139 (38%), Gaps = 22/139 (15%) Query: 1552 CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV 1611 C P GA V DQ+ C C + C + CP G + C C CD Sbjct: 2 CNCNPEGATNLVCDQSTG--RCPCRT--RIRGKKC-----DLCPLGHFNFPRCKGCDCDP 52 Query: 1612 TRGYHPHCNKENGKCHCKENHYKPE---------GTAECLPCQCYAAGSENSSCEAATGQ 1662 C+ G C CK+N G C+ C C +G +C G+ Sbjct: 53 LTTKDEICDN-TGSCVCKDNFQGHRCQKCMTGYYGFPLCIKCACSNSGF--GTC-GQYGE 108 Query: 1663 CHCRPGVIGRACDACANAY 1681 C CRPG GR+C++CA + Sbjct: 109 CICRPGYTGRSCESCAKGF 127 Score = 48.8 bits (111), Expect = 6e-05 Identities = 53/197 (26%), Positives = 70/197 (35%), Gaps = 27/197 (13%) Query: 1521 ICPPYSKCVT--SWDSSTCT-CEAGRVG-PQCVS-ACE---LGPCGA-ARCVPDQTPKGY 1571 IC CV ++ C C G G P C+ AC G CG C+ G Sbjct: 59 ICDNTGSCVCKDNFQGHRCQKCMTGYYGFPLCIKCACSNSGFGTCGQYGECICRPGYTGR 118 Query: 1572 SC-ACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 SC +C G+ E G E C C+V C++ +GKC CK+ Sbjct: 119 SCESCAKGFYGFPHCTGEYGLSENGIPVVNSITVATCNCNVQGSESQSCDQASGKCTCKK 178 Query: 1631 N--HYKPEGTAE-------CLPCQCYAAGS------ENSSCEAATGQCHCRPGVIGRACD 1675 N +K + A+ C C C G+ C A C C+ V G CD Sbjct: 179 NVIGWKCDMCAKDLVSFPACTKCNCDPGGTVVLPGQSKVGCFGAKQSCMCKMNVQGTLCD 238 Query: 1676 ACANAYAEVTPN--SGC 1690 C Y + SGC Sbjct: 239 RCRFGYFNFSAENPSGC 255 Score = 44.0 bits (99), Expect = 0.002 Identities = 16/48 (33%), Positives = 24/48 (50%) Query: 1644 CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691 C C G+ N C+ +TG+C CR + G+ CD C + GC+ Sbjct: 2 CNCNPEGATNLVCDQSTGRCPCRTRIRGKKCDLCPLGHFNFPRCKGCD 49 Score = 34.3 bits (75), Expect = 1.4 Identities = 37/150 (24%), Positives = 51/150 (34%), Gaps = 25/150 (16%) Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593 S CTC+ +G +C C C C C+PG T+ G K Sbjct: 171 SGKCTCKKNVIGWKC-DMCAKDLVSFPACT--------KCNCDPGGTVVLPG---QSKVG 218 Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653 C G A C C + C++ C ++ E + C C C G+ Sbjct: 219 CFG------AKQSCMCKMNV-QGTLCDR----CRFGYFNFSAENPSGCTTCGCSTRGTMA 267 Query: 1654 S--SCEAATGQCHCRPGVIGRACDACANAY 1681 + C TG C C+ V G A A Y Sbjct: 268 AMRGCHHVTGICSCKNYVTGSKLTASARVY 297 >SB_8046| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1304 Score = 64.9 bits (151), Expect = 9e-10 Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 27/179 (15%) Query: 1537 CTCEAGRVGP--QCVSACELGPCGAAR-CVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593 C AG G Q ACE GA V DQ G C+C P I +E Sbjct: 679 CQVLAGFYGDLYQKGQACECNATGAVTPSVCDQC--GGQCSCRPHV-------IGRKCDE 729 Query: 1594 CPGGWW---GGSACGPCACDVTRGYHPHCNKENGKCHCK------------ENHYKPEGT 1638 C ++ G C CAC++T C+ + GKC C ++++ Sbjct: 730 CRPDYYDFTSGLGCKACACNMTGSKRSSCHPDTGKCECHPSITERQCSRCLDHYFNFTSG 789 Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGC 1697 C PC C S + C+ TG C C+ GV G C C++A+ +T G + C Sbjct: 790 VGCQPCGCNELYSRDLQCDNDTGVCSCKDGVGGAKCTECSDAFYNLTLKVGSHLPVGQC 848 Score = 49.6 bits (113), Expect = 4e-05 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 6/61 (9%) Query: 1637 GTAECLPCQCYAAG----SENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNS--GC 1690 G A + C C G N+ C A TG+C C+P V GRACD C + ++ S GC Sbjct: 290 GLAVFIDCACTLTGVRNMPNNTECNAVTGECDCKPNVQGRACDTCKDTMWNISNTSPQGC 349 Query: 1691 E 1691 + Sbjct: 350 Q 350 Score = 46.4 bits (105), Expect = 3e-04 Identities = 18/37 (48%), Positives = 19/37 (51%) Query: 1641 CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC 1677 C CQC GS N C G C CR IGR CD+C Sbjct: 894 CTGCQCDLNGSLNPVCNKLNGNCTCRSNAIGRLCDSC 930 Score = 42.7 bits (96), Expect = 0.004 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 TA C C C AGS N +C G CHCRP G CD + Sbjct: 430 TAGCSACNCDPAGSINVTCSDG-GACHCRPHFSGLKCDVIERGF 472 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKEN 1631 C C CD+ +P CNK NG C C+ N Sbjct: 894 CTGCQCDLNGSLNPVCNKLNGNCTCRSN 921 Score = 32.3 bits (70), Expect = 5.8 Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 1663 CHCRPGVIGRACDACANAYAEVTPNSG 1689 C C +G+ C+ CA Y TPN G Sbjct: 1161 CQCPIQYVGQFCERCAPGYTRATPNGG 1187 >SB_25851| Best HMM Match : Laminin_G_2 (HMM E-Value=0) Length = 683 Score = 63.7 bits (148), Expect = 2e-09 Identities = 103/398 (25%), Positives = 159/398 (39%), Gaps = 57/398 (14%) Query: 1111 PVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGP 1170 P SSF + L F T LL+Y + D+ LEL + GR Sbjct: 35 PKSSFAQHQQWRVSSNGTLTFSFKTFLKDALLIYQD--DGVMDYFNLEL---KVGR---- 85 Query: 1171 GLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLK 1230 L + G S++T+ + D SWH V I + I + LDD +V+ K Sbjct: 86 -LLLNIRTGRKTSQVTLGNQLNDLSWHQVSIHVEHVKIGLTLDDHTRVV----------K 134 Query: 1231 YACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISD--F 1288 N K P+R F L L I L + P+ V K F GCI D Sbjct: 135 IPRKNLALKNNPSRYLY-------FGGLPRSLSISTL-SFPAV--VFAKRFTGCIKDVEI 184 Query: 1289 YIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAEC-SDLWDTYICDCK-EGHTGK 1346 I + + V G + GC R+ C S PC NG C + +W + CDC G G Sbjct: 185 QIGNGVQEELRLVESKGRVRGC---RNACRSNPCQNGGRCINKIWSS-ACDCSGTGFYGN 240 Query: 1347 DCADSTGPPWRFGGDGMLS----------FNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ 1396 C + D ++ ++ ++ + + + ++T F++ ++ Sbjct: 241 QCTEEPPRLSMTASDYVIHDMSQEATATFYDHVVIDFRATSSDGIILQTSFASDFLL-VE 299 Query: 1397 LKSGLLHYSYNGETMYLPMA---TLSDGAWHRIEIKWLGTDISVTVDYGLR---TVLMPM 1450 L G+L + L ++ LSD WHR EIK ++ +T+D L+ T + Sbjct: 300 LHRGVLVMQLDIGAGMLKLSIGEKLSDARWHRAEIKRARRNVKLTLDERLKVDGTCPPSL 359 Query: 1451 LANKIQGQYIGKILIGGL-DTTAGLLASDVGFFEGCIQ 1487 A +QG G++ IGG+ D T + FEGCI+ Sbjct: 360 TAFNMQGGE-GRVYIGGVSDPTRSKNSVSRKNFEGCIR 396 Score = 44.8 bits (101), Expect = 0.001 Identities = 55/206 (26%), Positives = 84/206 (40%), Gaps = 21/206 (10%) Query: 1356 WRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSG--LLHYSYNGETMYL 1413 WR +G L+F+ + +AL I +++LK G LL+ +T + Sbjct: 45 WRVSSNGTLTFS-----FKTFLKDALLIYQDDGVMDYFNLELKVGRLLLNIRTGRKTSQV 99 Query: 1414 PMAT-LSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTA 1472 + L+D +WH++ I I +T+D R V +P ++ + GGL + Sbjct: 100 TLGNQLNDLSWHQVSIHVEHVKIGLTLDDHTRVVKIPRKNLALKNNPSRYLYFGGLPRSL 159 Query: 1473 GLLASD---VGF---FEGCIQDVRI---GTAQSLLNRPTVRENVRDGCQSRADCMLSICP 1523 + V F F GCI+DV I Q L + VR GC R C + C Sbjct: 160 SISTLSFPAVVFAKRFTGCIKDVEIQIGNGVQEELRLVESKGRVR-GC--RNACRSNPCQ 216 Query: 1524 PYSKCVTSWDSSTCTCE-AGRVGPQC 1548 +C+ SS C C G G QC Sbjct: 217 NGGRCINKIWSSACDCSGTGFYGNQC 242 >SB_552| Best HMM Match : Laminin_EGF (HMM E-Value=1.3e-23) Length = 198 Score = 63.7 bits (148), Expect = 2e-09 Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 9/168 (5%) Query: 1530 TSWDSSTCTCEAGRVGPQCVS-ACELGPCGAARCVP-DQTPKGYSCA-CEPGYTLTTSGC 1586 TS D C C G + +C LG G C ++ G C C+ GY T + Sbjct: 11 TSSDCRECPCPGGPFSANSFARSCVLGSDGLPTCTNCSESHAGRQCERCQDGYYGTPTDP 70 Query: 1587 IESGKEECPGGWWGGSACGPCA-CDVTRGYHPHC--NKENGKCHCKENHYKPEGTAE-CL 1642 + +C G G C+ T G C N C + + TA+ C Sbjct: 71 VNGQCRKCNCN--GNVDPGVTGNCNTTTGECLKCLYNTSGFNCQWCVSGFHGNATAKTCQ 128 Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 C C GS++ C TGQC C P V G +C+ C T GC Sbjct: 129 ACNCTDRGSKHGVCNNVTGQCDCHPLVTGLSCERCVKDAFNYTSGKGC 176 Score = 38.7 bits (86), Expect = 0.066 Identities = 50/184 (27%), Positives = 72/184 (39%), Gaps = 39/184 (21%) Query: 1515 ADCMLSICP--PYS------KCVTSWDS-STCT-CEAGRVGPQCVSACELGPCGAARCVP 1564 +DC CP P+S CV D TCT C G QC C+ G G Sbjct: 13 SDCRECPCPGGPFSANSFARSCVLGSDGLPTCTNCSESHAGRQC-ERCQDGYYGTPTDPV 71 Query: 1565 DQTPKGYSCA--CEPGYT----LTTSGCIE-----SGK--EECPGGWWGGSACGPC-ACD 1610 + + +C +PG T TT C++ SG + C G+ G + C AC+ Sbjct: 72 NGQCRKCNCNGNVDPGVTGNCNTTTGECLKCLYNTSGFNCQWCVSGFHGNATAKTCQACN 131 Query: 1611 VT-RGY-HPHCNKENGKCHCK------------ENHYKPEGTAECLPCQCYAAGSENSSC 1656 T RG H CN G+C C ++ + C C C+ GS ++ C Sbjct: 132 CTDRGSKHGVCNNVTGQCDCHPLVTGLSCERCVKDAFNYTSGKGCTACGCHPQGSNDTQC 191 Query: 1657 EAAT 1660 +A + Sbjct: 192 DAVS 195 >SB_49286| Best HMM Match : Laminin_N (HMM E-Value=0) Length = 1465 Score = 63.3 bits (147), Expect = 3e-09 Identities = 24/46 (52%), Positives = 30/46 (65%), Gaps = 3/46 (6%) Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678 + P+G C PC C GS N++C TGQCHC+PGV GR CD C+ Sbjct: 1025 FPPKG---CEPCNCDTTGSWNNTCSVTTGQCHCKPGVTGRRCDQCS 1067 Score = 62.5 bits (145), Expect = 5e-09 Identities = 39/128 (30%), Positives = 56/128 (43%), Gaps = 16/128 (12%) Query: 1621 KENGKCHCKENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676 K N CK+ + + G+ A+C+PCQCY + +C+ TG+C+C+ G CD Sbjct: 679 KGNNCEQCKDGYTRQAGSTDRYAQCVPCQCYG---HSDTCDPVTGKCNCKHNTTGIRCDK 735 Query: 1677 CANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETI-TDCPPGSSGRATRTCDET 1735 C + Y P G CP F + G + TDCP G G CD Sbjct: 736 CIDGYYG-NPTQGTPDDCKKCPCKFGTRC----IQIGANVVCTDCPEGHVG---NLCDMC 787 Query: 1736 KDVPWQDP 1743 +D + DP Sbjct: 788 QDGYYGDP 795 Score = 45.2 bits (102), Expect = 8e-04 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 5/71 (7%) Query: 1625 KCH-CKENHYKPEGTAECLPCQCYAAGSENSSCEA-ATGQCHCRPGVIGRACDACANAY- 1681 KC C+ N++ T C PCQC+ G++ + + G+C C+ V+G C C + Y Sbjct: 400 KCDKCQANYFGFSQTG-CRPCQCFGPGTDPAKTQCNEKGECTCKRHVVGAKCTLCRSGYF 458 Query: 1682 -AEVTPNSGCE 1691 E + GC+ Sbjct: 459 GLEASNPHGCK 469 Score = 42.3 bits (95), Expect = 0.005 Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 13/66 (19%) Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKE------------NHYKPEGTAECLPCQCYAAGS 1651 C PC CD T ++ C+ G+CHCK +HY CL C C GS Sbjct: 1030 CEPCNCDTTGSWNNTCSVTTGQCHCKPGVTGRRCDQCSIDHY-AFSELGCLACNCNLQGS 1088 Query: 1652 ENSSCE 1657 N +C+ Sbjct: 1089 LNVTCD 1094 Score = 38.7 bits (86), Expect = 0.066 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 19/133 (14%) Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKEN 1623 P+Q C+C Y + G G + C PC C G+ C+ Sbjct: 663 PNQVNWVEQCSCPKEYKGNNCEQCKDGYTRQAGSTDRYAQCVPCQC---YGHSDTCDPVT 719 Query: 1624 GKCHCKEN------------HY--KPEGTA-ECLPCQCYAAGSENSSCEAATGQCHCRPG 1668 GKC+CK N +Y +GT +C C C G+ A C G Sbjct: 720 GKCNCKHNTTGIRCDKCIDGYYGNPTQGTPDDCKKCPC-KFGTRCIQIGANVVCTDCPEG 778 Query: 1669 VIGRACDACANAY 1681 +G CD C + Y Sbjct: 779 HVGNLCDMCQDGY 791 Score = 36.3 bits (80), Expect = 0.35 Identities = 45/179 (25%), Positives = 60/179 (33%), Gaps = 25/179 (13%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCT-CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCA 1574 DC C ++C+ + CT C G VG C C+ G G +G Sbjct: 751 DCKKCPCKFGTRCIQIGANVVCTDCPEGHVGNLC-DMCQDGYYG-----DPMGKRGAPTT 804 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHY- 1633 C+ SG I+ G C C + G C + HY Sbjct: 805 CQK---CNCSGNIDPNAIGSCDRLTGD--CLKCIHNTRNGPISQCELCAIGYYGNATHYP 859 Query: 1634 KPEGTAECLPCQCYAAGSENSSCEAAT--------GQCHCRPGVIGRACDACANAYAEV 1684 KP+ C C+CY G+ + T G+C C P V G CD C Y V Sbjct: 860 KPQ----CKACECYVQGTVSPPGHDPTLPFPCDDKGRCTCLPNVSGDKCDTCRPEYWNV 914 Score = 35.1 bits (77), Expect = 0.82 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 1654 SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 S C + GQC C+PGV G CD C Y + +GC Sbjct: 382 SDCNSE-GQCRCKPGVTGIKCDKCQANYFGFS-QTGC 416 Score = 34.3 bits (75), Expect = 1.4 Identities = 13/33 (39%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 1317 CSSAPCYNGAECSDLWDTYIC-DCKEGHTGKDC 1348 C PC G C + +C DC EGH G C Sbjct: 752 CKKCPCKFGTRCIQIGANVVCTDCPEGHVGNLC 784 >SB_22952| Best HMM Match : EGF_2 (HMM E-Value=2e-23) Length = 300 Score = 63.3 bits (147), Expect = 3e-09 Identities = 49/176 (27%), Positives = 67/176 (38%), Gaps = 15/176 (8%) Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593 + TC+C+ G G C C G G +C+ G TSG E+ Sbjct: 115 NGTCSCQTGWTGENCDITCSQGRWGVGCQGTCDCKNNATCSPFTGQCNCTSGFTGDRCEK 174 Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP------CQCY 1647 G GG C C+ T CN GKC C+ Y + AEC C + Sbjct: 175 QCAGDSGGVDCRQ-HCNCTEW--GTCNPFTGKCLCQSGFYGEDCGAECPDGTYGPACTAH 231 Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANAY---AEVT---PNSGCEVVYDGC 1697 +N++C+ G C C+PG G C+ Y E T N+ C+VV C Sbjct: 232 CKCQKNATCDKIDGTCQCKPGWTGIDCECSPGKYGNKCEKTCSCNNNYCDVVTGVC 287 Score = 54.8 bits (126), Expect = 9e-07 Identities = 49/174 (28%), Positives = 65/174 (37%), Gaps = 25/174 (14%) Query: 1510 GCQSRADCMLSI-CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTP 1568 GCQ DC + C P++ C C +G G +C C G G C Sbjct: 141 GCQGTCDCKNNATCSPFT--------GQCNCTSGFTGDRCEKQCA-GDSGGVDCRQHCNC 191 Query: 1569 KGYSCACEP--GYTLTTSGCI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625 + C P G L SG E ECP G +G + C C + C+K +G Sbjct: 192 TEWG-TCNPFTGKCLCQSGFYGEDCGAECPDGTYGPACTAHCKCQK----NATCDKIDGT 246 Query: 1626 CHCKENHYKPEGTAECLPCQ----CYAAGS-ENSSCEAATGQCHCRPGVIGRAC 1674 C CK + EC P + C S N+ C+ TG C+C G C Sbjct: 247 CQCKPGWTGID--CECSPGKYGNKCEKTCSCNNNYCDVVTGVCNCPHGYERPTC 298 >SB_42841| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1651 Score = 63.3 bits (147), Expect = 3e-09 Identities = 30/67 (44%), Positives = 39/67 (58%), Gaps = 3/67 (4%) Query: 1640 ECLPCQCYAAGSENSS-CEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCP 1698 EC PC C GS NSS C+ TGQC C+PGV G+ CD C+ + T ++GC + D C Sbjct: 16 ECQPCACNKTGSYNSSTCDRETGQCKCKPGVAGQNCDRCSVQHVNFT-DTGC-IACDICT 73 Query: 1699 RSFAGGV 1705 R G+ Sbjct: 74 RLGLQGI 80 Score = 35.9 bits (79), Expect = 0.47 Identities = 13/27 (48%), Positives = 18/27 (66%), Gaps = 1/27 (3%) Query: 1604 CGPCACDVTRGYHPH-CNKENGKCHCK 1629 C PCAC+ T Y+ C++E G+C CK Sbjct: 17 CQPCACNKTGSYNSSTCDRETGQCKCK 43 >SB_52794| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1408 Score = 62.1 bits (144), Expect = 6e-09 Identities = 70/264 (26%), Positives = 106/264 (40%), Gaps = 35/264 (13%) Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDL-WDTYICDCKEGHTGKDCADSTG 1353 D + N T C ++ C PC NG C D+ ++ + CDC G G C +ST Sbjct: 887 DFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCIDIGFENFTCDCSAGFGGPLCENST- 945 Query: 1354 PPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS-------IQLKSGLLHYSY 1406 G L+F+ Q ++ AL RT D ++ +QL+ G + S Sbjct: 946 -TVSLNGSSYLTFD----GSQSEFMVALEFRTTLPDGVLVHDSESKFLLQLREGAIEIS- 999 Query: 1407 NGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466 NG + A LSDG W I + T + + +V + + K +IG L Sbjct: 1000 NGASSAAIEAALSDGNWSGI-VGLNVTQSHLHLSINTSSVSIARINRKNPKLFIGGYL-E 1057 Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVR--DGCQSRADCMLSICPP 1524 L+ L+ GCI+DV++ S++ P+ E VR GC C C Sbjct: 1058 SLEKRRNLI--------GCIRDVKV---NSVVKLPSEMELVRVSMGCPREEVCSPDPC-T 1105 Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQC 1548 C+ W + C C+ GP C Sbjct: 1106 NGTCIDEWLTYRCACDR---GPNC 1126 Score = 50.8 bits (116), Expect = 2e-05 Identities = 58/212 (27%), Positives = 78/212 (36%), Gaps = 30/212 (14%) Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV----SACELGPC-GAARC 1562 D C+ D C + C YS C+ ++ TC C G C + C+ PC C Sbjct: 432 DYCEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLCDPNPCQNGGVC 491 Query: 1563 VPDQTPKGYSCACEPGYT-LTTSGCIESGKE-ECPGGWW-----GGSACGPCACDVTRGY 1615 Y+CAC GYT +G + + C G S C C VT GY Sbjct: 492 KETFDRNIYTCACPQGYTGWNCNGTLHPCETLNCTNGGTCQKQSNASDDYVCVC-VTVGY 550 Query: 1616 HPH---CNKENG--KCHCKE--NHYKPE-GTAECLPCQCY-AAGSENSSCEAAT-----G 1661 + C G C C E N E EC C A +N+ C+ Sbjct: 551 CKNGATCTNTPGNYSCQCTEFTNGTNCELDINECASSPCLNGALCQNNDCDKTACFDKGY 610 Query: 1662 QCHCRPGVIGRACDACANA--YAEVTPNSGCE 1691 +C C+ G +G C+ + A V PN CE Sbjct: 611 ECFCKSGFLGPLCEIDLDECFLAAVDPNKRCE 642 Score = 46.0 bits (104), Expect = 4e-04 Identities = 17/41 (41%), Positives = 26/41 (63%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C + C+S PC NGA C+DL + + C C G+TG +C++ Sbjct: 825 CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSE 865 Score = 44.0 bits (99), Expect = 0.002 Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C S PC + A C+DL + + C+C +TG+ C Sbjct: 863 CSEDINECLSTPCQHSATCNDLVNDFSCNCTANYTGRQC 901 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/39 (43%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+DL + + C C G+TG C Sbjct: 705 CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGPLC 743 Score = 40.3 bits (90), Expect = 0.022 Identities = 16/44 (36%), Positives = 24/44 (54%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 C C+SAPC++ + C D + Y C C TG+DC+ + G Sbjct: 434 CEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLG 477 Score = 40.3 bits (90), Expect = 0.022 Identities = 39/157 (24%), Positives = 54/157 (34%), Gaps = 18/157 (11%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEP 1577 C + CV + C C G G +C + C LG C A C + Y+C C P Sbjct: 641 CENGATCVDKVNRKECICPPGWTGDRCHVDIDECALGFCDNGATC--NNFNGTYNCTCVP 698 Query: 1578 GYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCH--CKENH 1632 GYT ++ E C G C GY P C + +C + + Sbjct: 699 GYTDRNCSTDINECASNPCENGATCNDLINYFNCTCVPGYTGPLCETDVDECFLAAVDPN 758 Query: 1633 YKPEGTAECL------PCQCYAAGSENSSCEAATGQC 1663 + E A C+ C C G C G+C Sbjct: 759 KRCENGATCVDKVNGKECIC-PLGWTGDRCHVYIGKC 794 Score = 39.9 bits (89), Expect = 0.029 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 27/165 (16%) Query: 998 DDNICVHEPCLNFEECLTVLKFGNAS------GFVNSDSV---LFRPIYP-------VTS 1041 D N C PC N C ++ + N + GF S+ + L P V Sbjct: 828 DINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSEDINECLSTPCQHSATCNDLVND 887 Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 F+C C +TG CE + K C C +G +C+ + G C A + Sbjct: 888 FSCNCTANYTGRQCEYL--KTLCRPINP---CLNGGRCI---DIGFENFTCDCSAGFGGP 939 Query: 1102 VCELRAR-SFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN 1145 +CE S SS+LTF G + + L+F T G+L+++ Sbjct: 940 LCENSTTVSLNGSSYLTFDGSQSEFMV--ALEFRTTLPDGVLVHD 982 Score = 38.3 bits (85), Expect = 0.088 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354 C PC NG C + +D Y C C +G+TG +C + P Sbjct: 480 CDPNPCQNGGVCKETFDRNIYTCACPQGYTGWNCNGTLHP 519 Score = 37.5 bits (83), Expect = 0.15 Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 7/77 (9%) Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563 D C D C L C + C + CTC G C ++ C PC A C Sbjct: 665 DRCHVDIDECALGFCDNGATCNNFNGTYNCTCVPGYTDRNCSTDINECASNPCENGATC- 723 Query: 1564 PDQTPKGYSCACEPGYT 1580 + ++C C PGYT Sbjct: 724 -NDLINYFNCTCVPGYT 739 Score = 36.7 bits (81), Expect = 0.27 Identities = 44/174 (25%), Positives = 61/174 (35%), Gaps = 26/174 (14%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCAC 1575 +C + C + C + CTC G GP C + ++ C A P++ C Sbjct: 711 ECASNPCENGATCNDLINYFNCTCVPGYTGPLCET--DVDECFLAAVDPNK-------RC 761 Query: 1576 EPGYTLTTSGCIE--SGKE-ECPGGWWGGSA---CGPCACDVTRGYHPHCNKENG--KCH 1627 E G T C++ +GKE CP GW G G CA CN NG C Sbjct: 762 ENGAT-----CVDKVNGKECICPLGWTGDRCHVYIGKCALGFCDN-GATCNNFNGTYNCT 815 Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACAN 1679 C + + + C ++C C C PG G C N Sbjct: 816 CVPGYTDRNCSTDINECASNPC-ENGATCNDLINYFNCTCVPGYTGFNCSEDIN 868 Score = 36.7 bits (81), Expect = 0.27 Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 +C+ C NGA C++ TY C C G+T ++C+ Sbjct: 793 KCALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 826 Score = 36.3 bits (80), Expect = 0.35 Identities = 14/40 (35%), Positives = 21/40 (52%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C+ C NGA C++ TY C C G+T ++C+ Sbjct: 667 CHVDIDECALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 706 Score = 33.5 bits (73), Expect = 2.5 Identities = 14/47 (29%), Positives = 21/47 (44%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 + F C C G+TG CET + + C +G+ CV + G Sbjct: 727 INYFNCTCVPGYTGPLCETDVDECFLAAVDPNKRCENGATCVDKVNG 773 Score = 32.3 bits (70), Expect = 5.8 Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS 1077 +TC CP+G+TG NC L +G C+ S Sbjct: 500 YTCACPQGYTGWNCNGTLHPCETLNCTNGGTCQKQS 535 Score = 32.3 bits (70), Expect = 5.8 Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 6/69 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACE-LGPC-GAARCVPDQTPKG 1570 +C+ + C + C + +C C A G QC + C + PC RC+ D + Sbjct: 869 ECLSTPCQHSATCNDLVNDFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCI-DIGFEN 927 Query: 1571 YSCACEPGY 1579 ++C C G+ Sbjct: 928 FTCDCSAGF 936 >SB_56285| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1127 Score = 61.7 bits (143), Expect = 8e-09 Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 10/112 (8%) Query: 1652 ENSSCEAATGQ--CHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPR 1709 E++ C G C CR G+IG + ++ P + CP + G+ WPR Sbjct: 327 EDAECINMRGSYTCMCREGLIG-------DGHSCKVPEFSTADLLTYCPAHYENGIMWPR 379 Query: 1710 TKFGVETITDCPPGSSGRATRTCDETKDVP-WQDPDMFNCTTATFYQLRKQL 1760 T I CP S+G A+R C D P W+ PDM C T ++ K+L Sbjct: 380 TAHAQTQIQRCPKDSTGVASRQCSGPADSPEWEIPDMSQCVTDAIARIHKEL 431 >SB_50568| Best HMM Match : EGF (HMM E-Value=0) Length = 792 Score = 61.7 bits (143), Expect = 8e-09 Identities = 70/264 (26%), Positives = 107/264 (40%), Gaps = 35/264 (13%) Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDL-WDTYICDCKEGHTGKDCADSTG 1353 D + N T C ++ C PC NG C D+ ++ + CDC G G C +ST Sbjct: 216 DFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCIDIGFENFTCDCSAGFGGPLCENST- 274 Query: 1354 PPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS-------IQLKSGLLHYSY 1406 G L+F+ Q ++ AL RT D ++ +QLK G + S Sbjct: 275 -TVSLNGSSYLTFD----GSQSEFMVALEFRTTLADGVLVHDSESKFLLQLKEGAIEIS- 328 Query: 1407 NGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466 NG + A LS+G W I + T + + +V + + K +IG L Sbjct: 329 NGASSAAIGAKLSNGNWSGI-VGLNVTQSHLQLSINTLSVSITRINRKNPKLFIGGYL-E 386 Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVR--DGCQSRADCMLSICPP 1524 L+ L+ GCI+DV++ S++ P+ E VR GC C C Sbjct: 387 SLEKRRNLI--------GCIRDVKV---NSVVKLPSEIELVRVSMGCPREEVCSPDPC-T 434 Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQC 1548 + C+ W + C C+ GP C Sbjct: 435 HGTCIDEWLTYRCACDR---GPNC 455 Score = 46.0 bits (104), Expect = 4e-04 Identities = 17/41 (41%), Positives = 26/41 (63%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C + C+S PC NGA C+DL + + C C G+TG +C++ Sbjct: 154 CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSE 194 Score = 44.8 bits (101), Expect = 0.001 Identities = 18/43 (41%), Positives = 24/43 (55%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C + C+S PC NGA C+DL + + C C G+TG C T Sbjct: 34 CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGPLCETDT 76 Score = 44.0 bits (99), Expect = 0.002 Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C S PC + A C+DL + + C+C +TG+ C Sbjct: 192 CSEDINECLSTPCQHNATCNDLVNDFSCNCTANYTGRQC 230 Score = 40.3 bits (90), Expect = 0.022 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 27/165 (16%) Query: 998 DDNICVHEPCLNFEECLTVLKFGNAS------GFVNSDSV---LFRPIYP-------VTS 1041 D N C PC N C ++ + N + GF S+ + L P V Sbjct: 157 DINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSEDINECLSTPCQHNATCNDLVND 216 Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 F+C C +TG CE + K C C +G +C+ + G C A + Sbjct: 217 FSCNCTANYTGRQCEYL--KTLCRPINP---CLNGGRCI---DIGFENFTCDCSAGFGGP 268 Query: 1102 VCELRAR-SFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN 1145 +CE S SS+LTF G + + L+F T G+L+++ Sbjct: 269 LCENSTTVSLNGSSYLTFDGSQSEFMV--ALEFRTTLADGVLVHD 311 Score = 37.5 bits (83), Expect = 0.15 Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 9/83 (10%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C L C + C + CTC G C ++ C PC A C + + Sbjct: 2 ECALGFCDNGATCNNFNGTYNCTCVPGYTDRNCSTDINECASNPCENGATC--NDLINYF 59 Query: 1572 SCACEPGYTLTTSGCIESGKEEC 1594 +C C PGY T E+ +EC Sbjct: 60 NCTCVPGY---TGPLCETDTDEC 79 Score = 36.7 bits (81), Expect = 0.27 Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 +C+ C NGA C++ TY C C G+T ++C+ Sbjct: 122 KCALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 155 Score = 35.9 bits (79), Expect = 0.47 Identities = 13/33 (39%), Positives = 20/33 (60%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C+ C NGA C++ TY C C G+T ++C+ Sbjct: 3 CALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 35 Score = 35.9 bits (79), Expect = 0.47 Identities = 44/174 (25%), Positives = 60/174 (34%), Gaps = 26/174 (14%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCAC 1575 +C + C + C + CTC G GP C + + C A P++ C Sbjct: 40 ECASNPCENGATCNDLINYFNCTCVPGYTGPLCET--DTDECFLAAVDPNK-------RC 90 Query: 1576 EPGYTLTTSGCIE--SGKE-ECPGGWWGGSA---CGPCACDVTRGYHPHCNKENG--KCH 1627 E G T C++ +GKE CP GW G G CA CN NG C Sbjct: 91 ENGAT-----CVDKVNGKECICPLGWTGDRCHVYIGKCALGFCDN-GATCNNFNGTYNCT 144 Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACAN 1679 C + + + C ++C C C PG G C N Sbjct: 145 CVPGYTDRNCSTDINECASNPC-ENGATCNDLINYFNCTCVPGYTGFNCSEDIN 197 Score = 32.7 bits (71), Expect = 4.4 Identities = 14/47 (29%), Positives = 20/47 (42%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 + F C C G+TG CET + C +G+ CV + G Sbjct: 56 INYFNCTCVPGYTGPLCETDTDECFLAAVDPNKRCENGATCVDKVNG 102 Score = 32.3 bits (70), Expect = 5.8 Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 6/69 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACE-LGPC-GAARCVPDQTPKG 1570 +C+ + C + C + +C C A G QC + C + PC RC+ D + Sbjct: 198 ECLSTPCQHNATCNDLVNDFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCI-DIGFEN 256 Query: 1571 YSCACEPGY 1579 ++C C G+ Sbjct: 257 FTCDCSAGF 265 >SB_9550| Best HMM Match : GPS (HMM E-Value=1.6e-11) Length = 1771 Score = 61.3 bits (142), Expect = 1e-08 Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 18/142 (12%) Query: 1697 CPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVP-WQDPDMFNCTTATFYQ 1755 CP A + WP T + CP G+SG A R C + V W+ PD+ NC + F Sbjct: 26 CPFEIARNITWPATYSEEQARQACPSGTSGTAVRMCTQKSGVAVWEPPDLENCVSVRFAL 85 Query: 1756 LRKQLHKIETGELTMNTFVGVRVAADLSTACANT------PRLYGADVVVAEGILLELMD 1809 L+++L K T + AADL+ A A ++YG DV +A +L + Sbjct: 86 LQEKLSK---------TIINANAAADLADALAQVTSPSRDEQIYGGDVKIAVS-MLRALG 135 Query: 1810 YELRQAGLNLTHSQDKDYVRNL 1831 + N+T ++K+ +RN+ Sbjct: 136 HNTAIDPHNVT-EEEKEKMRNV 156 Score = 35.5 bits (78), Expect = 0.62 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 2238 CTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATV 2297 C C HL++FAVL+ F ++ T IS+ LL S A L Sbjct: 336 CHCYHLTSFAVLMQHSPDTFAVTSQHQFALGLITYIGISISLLALSLALLTFSTFTFLKS 395 Query: 2298 S-NSIHKHLIFSVFMAELLYLIAL 2320 S N H +L S+ +AE+++L+ + Sbjct: 396 SRNFAHINLTLSLILAEVIFLVGI 419 >SB_52147| Best HMM Match : EGF (HMM E-Value=0) Length = 364 Score = 60.9 bits (141), Expect = 1e-08 Identities = 55/199 (27%), Positives = 69/199 (34%), Gaps = 18/199 (9%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA---CELGPCGAARCVPDQT 1567 C SR D LS Y KCV S C C++G G C +A C L PC C+ Sbjct: 19 CDSRVDWCLSSPCKYGKCVNYAGSHGCMCDSGFTGKLCENAQDPCALHPCVNGDCISSND 78 Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGYHPH-CNKE 1622 + C C GY T C E+ + C C CD Y H C Sbjct: 79 T--FRCVCSEGY--TGDRC-ETVVDMCISAPCHNGTCINYGSSYICDCFNSYTGHLCETL 133 Query: 1623 NGKCHCKE-NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 CH N C+C AG SC+ C P G + Y Sbjct: 134 IDACHSNPCNDGTCIQQTGSFYCEC-LAGYTGQSCDTMIDACQSNPCNDGTCIQQTGSFY 192 Query: 1682 AE-VTPNSG--CEVVYDGC 1697 E +T +G C+ + D C Sbjct: 193 CECLTGYTGQSCDTMIDAC 211 Score = 49.6 bits (113), Expect = 4e-05 Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 13/110 (11%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQT 1567 C + D S + C+ S C+C+A VG +C V+ C PC C+PD + Sbjct: 204 CDTMIDACQSNPCVHGTCIPDGSSFRCSCDAKHVGEKCNIVVNVCLSNPCAHGICIPDAS 263 Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP------CACDV 1611 YSC CE Y+ I P G G C P CACDV Sbjct: 264 --SYSCMCEFMYSGKNCDIIVDPCSANPCGNHG--MCVPRDSTYYCACDV 309 Score = 44.4 bits (100), Expect = 0.001 Identities = 52/218 (23%), Positives = 75/218 (34%), Gaps = 26/218 (11%) Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPD 1565 D C++ D +S C+ S C C G C + AC PC C+ Sbjct: 91 DRCETVVDMCISAPCHNGTCINYGSSYICDCFNSYTGHLCETLIDACHSNPCNDGTCI-Q 149 Query: 1566 QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGY-HPHCN 1620 QT Y C C GY T C ++ + C C G C+ GY C+ Sbjct: 150 QTGSFY-CECLAGY--TGQSC-DTMIDACQSNPCNDGTCIQQTGSFYCECLTGYTGQSCD 205 Query: 1621 KENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC 1677 C C P+G++ C C A C C P G C Sbjct: 206 TMIDACQSNPCVHGTCIPDGSS--FRCSC-DAKHVGEKCNIVVNVCLSNPCAHG-ICIPD 261 Query: 1678 ANAYA----EVTPNSGCEVVYDGCPRSFAG--GVWWPR 1709 A++Y+ + C+++ D C + G G+ PR Sbjct: 262 ASSYSCMCEFMYSGKNCDIIVDPCSANPCGNHGMCVPR 299 Score = 41.1 bits (92), Expect = 0.012 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 8/81 (9%) Query: 1505 ENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCG-AA 1560 ++V + C + LS + C+ S +C CE G C V C PCG Sbjct: 235 KHVGEKCNIVVNVCLSNPCAHGICIPDASSYSCMCEFMYSGKNCDIIVDPCSANPCGNHG 294 Query: 1561 RCVP-DQTPKGYSCACEPGYT 1580 CVP D T Y CAC+ G+T Sbjct: 295 MCVPRDST---YYCACDVGFT 312 Score = 40.3 bits (90), Expect = 0.022 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C SAPC+NG C + +YICDC +TG C Sbjct: 93 CETVVDMCISAPCHNGT-CINYGSSYICDCFNSYTGHLC 130 Score = 39.1 bits (87), Expect = 0.050 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+ PC NG +C DT+ C C EG+TG C Sbjct: 56 CENAQDPCALHPCVNG-DCISSNDTFRCVCSEGYTGDRC 93 Score = 33.9 bits (74), Expect = 1.9 Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C S PC +G C ++ C+C G+TG+ C Sbjct: 167 CDTMIDACQSNPCNDGT-CIQQTGSFYCECLTGYTGQSC 204 Score = 33.5 bits (73), Expect = 2.5 Identities = 14/32 (43%), Positives = 15/32 (46%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CS+ PC N C TY C C G TG C Sbjct: 285 CSANPCGNHGMCVPRDSTYYCACDVGFTGDRC 316 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 C + C S+PC G +C + ++ C C G TGK C ++ P Sbjct: 19 CDSRVDWCLSSPCKYG-KCVNYAGSHGCMCDSGFTGKLCENAQDP 62 Score = 33.1 bits (72), Expect = 3.3 Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C S PC +G C ++ C+C G+TG+ C Sbjct: 130 CETLIDACHSNPCNDGT-CIQQTGSFYCECLAGYTGQSC 167 Score = 31.9 bits (69), Expect = 7.6 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVA---RREGGILCQGCSIDAA 1097 +F C C EG+TG CET++ +G+ GS + G LC+ IDA Sbjct: 79 TFRCVCSEGYTGDRCETVVDMCISAPCHNGTCINYGSSYICDCFNSYTGHLCE-TLIDAC 137 Query: 1098 YT 1099 ++ Sbjct: 138 HS 139 Score = 31.9 bits (69), Expect = 7.6 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGS-ICRSGS 1077 SF C+C G+TG +C+T++ DG+ I ++GS Sbjct: 153 SFYCECLAGYTGQSCDTMIDACQSNPCNDGTCIQQTGS 190 >SB_32355| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 1358 Score = 60.9 bits (141), Expect = 1e-08 Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 1/51 (1%) Query: 1640 ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 + L C+C GS N +C+ GQCHC+PGV GR CD C + +T +GC Sbjct: 1096 QALACECNPDGSVNRTCQKYAGQCHCKPGVTGRKCDQCQQGFYNLT-TTGC 1145 Score = 52.0 bits (119), Expect = 7e-06 Identities = 29/71 (40%), Positives = 36/71 (50%), Gaps = 9/71 (12%) Query: 1620 NKENGKCH-CKENHYKPEGTAE-----CLPCQCYAAGSENSS--CEA-ATGQCHCRPGVI 1670 N E C C+ +Y+PE ++ C C C AG+ NSS CE A GQC C+ V Sbjct: 807 NTEGINCERCRPLYYRPENRSQNAVDACELCDCDTAGARNSSNICEGDAYGQCPCKQNVQ 866 Query: 1671 GRACDACANAY 1681 G CD C N Y Sbjct: 867 GLRCDTCNNTY 877 Score = 48.0 bits (109), Expect = 1e-04 Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 17/96 (17%) Query: 1603 ACGPCACDVT--RGYHPHCNKEN-GKCHCKEN------------HY--KPEGTAECLPCQ 1645 AC C CD R C + G+C CK+N +Y + T C PC Sbjct: 833 ACELCDCDTAGARNSSNICEGDAYGQCPCKQNVQGLRCDTCNNTYYGLSRQDTHGCRPCL 892 Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 C GS + C GQC C P + GR CD + Y Sbjct: 893 CDYGGSSSPVCNKTDGQCKCLPNIDGRQCDRPLDEY 928 >SB_10244| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 205 Score = 60.9 bits (141), Expect = 1e-08 Identities = 43/153 (28%), Positives = 58/153 (37%), Gaps = 23/153 (15%) Query: 1552 CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWG--GSACGPCAC 1609 C P G+ R + + P G C C+PG G C G++ C PC C Sbjct: 62 CSCDPLGS-RTLSECEPYGGQCRCKPGVEGRDCG-------RCKPGFYNMTSEGCRPCDC 113 Query: 1610 DVTRGYHPHCNKENGKCHCKENHYKPE-----------GTAECLPCQCYAAGSENSSCEA 1658 +V C+ G+C CK N + G A C C C GS + C+ Sbjct: 114 NVNGSSSSLCDHVTGQCSCKANVVGRDCSRCKVSSYGFGPAGCTECACNVHGSASLQCD- 172 Query: 1659 ATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691 +G C C VIG C C Y + P C+ Sbjct: 173 DSGVCPCNLEVIGTKCTQCKTGYFGL-PKMACK 204 Score = 57.2 bits (132), Expect = 2e-07 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 12/84 (14%) Query: 1606 PCACDVTRGYH-PHCNKENGKCHCKEN-------HYKP---EGTAE-CLPCQCYAAGSEN 1653 PC+CD C G+C CK KP T+E C PC C GS + Sbjct: 61 PCSCDPLGSRTLSECEPYGGQCRCKPGVEGRDCGRCKPGFYNMTSEGCRPCDCNVNGSSS 120 Query: 1654 SSCEAATGQCHCRPGVIGRACDAC 1677 S C+ TGQC C+ V+GR C C Sbjct: 121 SLCDHVTGQCSCKANVVGRDCSRC 144 Score = 50.4 bits (115), Expect = 2e-05 Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 2/50 (4%) Query: 1642 LPCQCYAAGSEN-SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 LPC C GS S CE GQC C+PGV GR C C + +T + GC Sbjct: 60 LPCSCDPLGSRTLSECEPYGGQCRCKPGVEGRDCGRCKPGFYNMT-SEGC 108 >SB_33333| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 583 Score = 60.5 bits (140), Expect = 2e-08 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 1626 CH-CKENHYKPEGT-----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 CH C+E YK C C C+ GS C +TGQC C+ GV+GR+CD CA Sbjct: 363 CHYCREGFYKDPNKHITHIKVCRQCNCHPHGSRGRVCNQSTGQCPCKEGVVGRSCDKCAP 422 Query: 1680 AYAEVTPN 1687 Y N Sbjct: 423 GYKSTKSN 430 >SB_31541| Best HMM Match : EGF (HMM E-Value=0) Length = 268 Score = 60.5 bits (140), Expect = 2e-08 Identities = 50/195 (25%), Positives = 70/195 (35%), Gaps = 16/195 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C+ +S TCTC AG G +C + C GPC D K ++ Sbjct: 3 ECAGNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDGVNK-FT 61 Query: 1573 CACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC--- 1626 C+C PG+T T + E C G C GY C + C Sbjct: 62 CSCIPGFTGTNCETDMDECADNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASG 121 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686 C+ +G + C C G ++CE +C P G C N++ P Sbjct: 122 PCQNGATCNDGVNK-YTCSC-IPGFTGANCETDMDECAGNPCANGGTCMDGINSFTCTCP 179 Query: 1687 ----NSGCEVVYDGC 1697 S CE D C Sbjct: 180 AGYTGSKCETDIDDC 194 Score = 51.2 bits (117), Expect = 1e-05 Identities = 50/175 (28%), Positives = 65/175 (37%), Gaps = 39/175 (22%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C++ D C + C C+ +S TCTC AG G +C + C GPC D Sbjct: 73 CETDMDECADNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 132 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 K Y+C+C PG+T + C E+ +EC G PCA G C Sbjct: 133 VNK-YTCSCIPGFT--GANC-ETDMDECAGN--------PCA-------------NGGTC 167 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 N + C C AG S CE C P G C+ N Y Sbjct: 168 MDGINSFT---------CTC-PAGYTGSKCETDIDDCASGPCQNGATCNDGVNKY 212 Score = 50.4 bits (115), Expect = 2e-05 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 8/92 (8%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C++ D C + C C+ +S TCTC AG G +C + C GPC D Sbjct: 149 CETDMDECAGNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 208 Query: 1567 TPKGYSCACEPGYTLT---TSGCIESGKEECP 1595 K Y+C+C PG+T T T+ C K+ P Sbjct: 209 VNK-YTCSCIPGFTGTNCETANCSGIIKDYTP 239 Score = 46.0 bits (104), Expect = 4e-04 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 7/64 (10%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362 C C+S PC NGA C+D + Y C C G TG +C + G P GG DG Sbjct: 111 CETDIDDCASGPCQNGATCNDGVNKYTCSCIPGFTGANCETDMDECAGNPCANGGTCMDG 170 Query: 1363 MLSF 1366 + SF Sbjct: 171 INSF 174 Score = 44.0 bits (99), Expect = 0.002 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V +TC C GFTG NCET + + + G+ C +G C+ GI C+ A Y Sbjct: 133 VNKYTCSCIPGFTGANCETDMDECA------GNPCANGGTCM----DGINSFTCTCPAGY 182 Query: 1099 TTAVCE 1104 T + CE Sbjct: 183 TGSKCE 188 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC NGA C+D + Y C C G TG +C Sbjct: 187 CETDIDDCASGPCQNGATCNDGVNKYTCSCIPGFTGTNC 225 Score = 42.7 bits (96), Expect = 0.004 Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T A C C+ PC NG C D +++ C C G+TG C Sbjct: 145 TGANCETDMDECAGNPCANGGTCMDGINSFTCTCPAGYTGSKC 187 Score = 42.3 bits (95), Expect = 0.005 Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC NGA C+D + + C C G TG +C Sbjct: 35 CETDIDDCASGPCQNGATCNDGVNKFTCSCIPGFTGTNC 73 Score = 42.3 bits (95), Expect = 0.005 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V FTC C GFTG NCET + + + + C +G C+ GI C+ A Y Sbjct: 57 VNKFTCSCIPGFTGTNCETDMDECA------DNPCANGGTCM----DGINSFTCTCPAGY 106 Query: 1099 TTAVCE 1104 T + CE Sbjct: 107 TGSKCE 112 Score = 41.1 bits (92), Expect = 0.012 Identities = 15/43 (34%), Positives = 20/43 (46%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T C C+ PC NG C D +++ C C G+TG C Sbjct: 69 TGTNCETDMDECADNPCANGGTCMDGINSFTCTCPAGYTGSKC 111 Score = 40.3 bits (90), Expect = 0.022 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + SFTC CP G+TG CET + D C++G+ C G+ CS + Sbjct: 95 INSFTCTCPAGYTGSKCETDID------DCASGPCQNGATC----NDGVNKYTCSCIPGF 144 Query: 1099 TTAVCE 1104 T A CE Sbjct: 145 TGANCE 150 Score = 39.5 bits (88), Expect = 0.038 Identities = 15/38 (39%), Positives = 21/38 (55%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 + SFTC CP G+TG CET + + +G+ C G Sbjct: 19 INSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 56 Score = 39.5 bits (88), Expect = 0.038 Identities = 15/38 (39%), Positives = 21/38 (55%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 + SFTC CP G+TG CET + + +G+ C G Sbjct: 171 INSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 208 Score = 38.7 bits (86), Expect = 0.066 Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ PC NG C D +++ C C G+TG C Sbjct: 4 CAGNPCANGGTCMDGINSFTCTCPAGYTGSKC 35 Score = 33.9 bits (74), Expect = 1.9 Identities = 12/19 (63%), Positives = 13/19 (68%) Query: 1039 VTSFTCQCPEGFTGVNCET 1057 V +TC C GFTG NCET Sbjct: 209 VNKYTCSCIPGFTGTNCET 227 >SB_25612| Best HMM Match : Cadherin (HMM E-Value=0.034) Length = 177 Score = 59.7 bits (138), Expect = 3e-08 Identities = 28/61 (45%), Positives = 40/61 (65%), Gaps = 2/61 (3%) Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQ 583 ++P TG + T++ LDRET++ Y LT+T D G P L + V I+V+D NDN PVF Q Sbjct: 117 VDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQ 176 Query: 584 Q 584 + Sbjct: 177 E 177 Score = 49.2 bits (112), Expect = 5e-05 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 +D +G L T LDRE V YT+ + D P+ + + AT+ + ++D+NDN P F Sbjct: 117 VDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLN-AAQPATVSITVLDENDNVPVFD 175 Query: 152 EK 153 ++ Sbjct: 176 QE 177 Score = 46.4 bits (105), Expect = 3e-04 Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 2/61 (3%) Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFES 689 +DP +GV+RT++ LDRE+V + L D G P ++ V I + D ND+ PVF+ Sbjct: 117 VDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQ 176 Query: 690 D 690 + Sbjct: 177 E 177 Score = 43.2 bits (97), Expect = 0.003 Identities = 19/39 (48%), Positives = 26/39 (66%) Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 T+DP +G + TS +LDRET +Y L +T D GDP +A Sbjct: 116 TVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNA 154 Score = 33.9 bits (74), Expect = 1.9 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 4/54 (7%) Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFE 470 G++ +Q LD + Y LT++ DSG + A V I + D N+ PVF+ Sbjct: 122 GVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFD 175 >SB_31961| Best HMM Match : EGF (HMM E-Value=0) Length = 2813 Score = 58.8 bits (136), Expect = 6e-08 Identities = 61/231 (26%), Positives = 79/231 (34%), Gaps = 18/231 (7%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C++ D C S C C ++ TCTC G G C + C PC D Sbjct: 1627 CEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITCDIDIDECASSPCQNGGFCTDM 1686 Query: 1567 TPKGYSCACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKEN 1623 ++C+C PGYT T E C G + C GY C+ Sbjct: 1687 I-NAFTCSCPPGYTGITCDINIDECASSPCQNGGFCTDMINAFTCTCLPGYTGITCDINI 1745 Query: 1624 GKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 C C+ +G E CQC +AG + CE +C P C N Sbjct: 1746 DDCASRPCQNGGICKDGINE-FKCQC-SAGFTGNLCEVNIDECASAPCQHRSTCKDLIND 1803 Query: 1681 Y-AEVTPN-SG--CEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGR 1727 Y P SG CE D C S + G + CPPG G+ Sbjct: 1804 YNCTCHPGYSGRNCEHEIDECISSPCRNKGYCYDAIGY-YLCICPPGFYGK 1853 Score = 55.2 bits (127), Expect = 7e-07 Identities = 20/39 (51%), Positives = 27/39 (69%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + ++C CKEG+TGKDC Sbjct: 1409 CGTEIDECASEPCKNGANCTDKINGFMCTCKEGYTGKDC 1447 Score = 54.8 bits (126), Expect = 9e-07 Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 12/176 (6%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TCTC+ G G C + C PC D+ G++ Sbjct: 1035 ECASNPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRI-NGFT 1093 Query: 1573 CACEPGYTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC--- 1626 CAC+PG+T G E + C G AC G+ C E +C Sbjct: 1094 CACKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDCGTEIDECASN 1153 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682 CK N C C G + C +C +P G C N +A Sbjct: 1154 PCK-NGATCTDRINGFTCTC-KPGFTDKDCGTEIDECASKPCKNGATCTDRINGFA 1207 Score = 54.8 bits (126), Expect = 9e-07 Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 24/187 (12%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + CTC+ G G C + C PC D+ G++ Sbjct: 1339 ECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRI-NGFA 1397 Query: 1573 CACEPGYTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCH-- 1627 C C+PG+T G E E C G C GY C + +C Sbjct: 1398 CTCKPGFTGKDCGTEIDECASEPCKNGANCTDKINGFMCTCKEGYTGKDCGTDIDECSSN 1457 Query: 1628 -------CKENHYK-PEGTAECLPCQCYAAGSENSSCE--AATGQCHCRPGVIGRAC--- 1674 C + Y P E CQ +CE A+ +C C+ G GR C Sbjct: 1458 PCLNEGTCTDQGYTGPNCEVEVNECQSDPC-QNGGTCEDLIASYRCFCKAGYTGRHCETD 1516 Query: 1675 -DACANA 1680 D CA++ Sbjct: 1517 IDECASS 1523 Score = 50.8 bits (116), Expect = 2e-05 Identities = 43/173 (24%), Positives = 68/173 (39%), Gaps = 26/173 (15%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TCTC+ G C + C PC D+ G++ Sbjct: 1149 ECASNPCKNGATCTDRINGFTCTCKPGFTDKDCGTEIDECASKPCKNGATCTDRI-NGFA 1207 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG-KCHCKEN 1631 CAC+PG+T GK +C G+ CA + + ++ NG C CK Sbjct: 1208 CACKPGFT---------GK-DC------GTEIDECASNPCKNGATCTDRINGFTCTCKPG 1251 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRAC----DACAN 1679 + E C + + + G +C C+PG G+ C D CA+ Sbjct: 1252 FTGKDCGTEIDECASKPCKNGATCTDRINGFRCTCKPGFTGKDCGTEIDECAS 1304 Score = 50.8 bits (116), Expect = 2e-05 Identities = 18/39 (46%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S+PC NG C+DL D + C C G+TGK+C Sbjct: 1513 CETDIDECASSPCANGGTCTDLVDAHKCQCSTGYTGKNC 1551 Score = 50.4 bits (115), Expect = 2e-05 Identities = 20/43 (46%), Positives = 26/43 (60%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T + C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1025 TGSDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGKDC 1067 Score = 50.4 bits (115), Expect = 2e-05 Identities = 43/173 (24%), Positives = 66/173 (38%), Gaps = 26/173 (15%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TCTC+ G G C + C PC D+ G+ Sbjct: 1225 ECASNPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRI-NGFR 1283 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG-KCHCKEN 1631 C C+PG+T GK +C G+ CA + + ++ NG C CK Sbjct: 1284 CTCKPGFT---------GK-DC------GTEIDECASNPCKNGATCTDRINGFTCTCKPG 1327 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRAC----DACAN 1679 + E C + + + G C C+PG G+ C D CA+ Sbjct: 1328 FTGSDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECAS 1380 Score = 50.4 bits (115), Expect = 2e-05 Identities = 20/43 (46%), Positives = 26/43 (60%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T + C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1329 TGSDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDC 1371 Score = 50.0 bits (114), Expect = 3e-05 Identities = 43/181 (23%), Positives = 57/181 (31%), Gaps = 12/181 (6%) Query: 1510 GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPD 1565 GC +C + C C +S CTC +G G +C C PC C D Sbjct: 877 GCVEIDECSSNPCQNGGTCTDQLNSYLCTCPSGYTGTKCEIVPDQCASAPCINGGTCKSD 936 Query: 1566 QTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKE 1622 + GY C C+ G+T + E C G C G+ C E Sbjct: 937 R--YGYHCHCKVGFTGKNCETNIDECNSSPCKNGGSCTDRISGFTCTCKHGFTGKDCGTE 994 Query: 1623 NGKCHCK--ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 +C K +N C C G S C +C P G C N Sbjct: 995 IDECASKPCKNGATCTDRINGFTCTC-KPGFTGSDCGTEIDECASNPCKNGATCTDRING 1053 Query: 1681 Y 1681 + Sbjct: 1054 F 1054 Score = 50.0 bits (114), Expect = 3e-05 Identities = 18/39 (46%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S+PC NG C+D + C CK G TGKDC Sbjct: 953 CETNIDECNSSPCKNGGSCTDRISGFTCTCKHGFTGKDC 991 Score = 50.0 bits (114), Expect = 3e-05 Identities = 19/39 (48%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1067 CGTEIDECASKPCKNGATCTDRINGFTCACKPGFTGKDC 1105 Score = 50.0 bits (114), Expect = 3e-05 Identities = 19/39 (48%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1105 CGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDC 1143 Score = 50.0 bits (114), Expect = 3e-05 Identities = 19/39 (48%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1181 CGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDC 1219 Score = 50.0 bits (114), Expect = 3e-05 Identities = 19/39 (48%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1219 CGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGKDC 1257 Score = 50.0 bits (114), Expect = 3e-05 Identities = 19/39 (48%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1371 CGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDC 1409 Score = 49.6 bits (113), Expect = 4e-05 Identities = 19/39 (48%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TGKDC Sbjct: 1257 CGTEIDECASKPCKNGATCTDRINGFRCTCKPGFTGKDC 1295 Score = 48.4 bits (110), Expect = 8e-05 Identities = 19/40 (47%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 1309 GCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 GC E CSS PC NG C+D ++Y+C C G+TG C Sbjct: 877 GCVEI-DECSSNPCQNGGTCTDQLNSYLCTCPSGYTGTKC 915 Score = 48.4 bits (110), Expect = 8e-05 Identities = 18/39 (46%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TG DC Sbjct: 991 CGTEIDECASKPCKNGATCTDRINGFTCTCKPGFTGSDC 1029 Score = 48.4 bits (110), Expect = 8e-05 Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 1303 DNG-TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 D G T C + + C S PC NG C DL +Y C CK G+TG+ C Sbjct: 1467 DQGYTGPNCEVEVNECQSDPCQNGGTCEDLIASYRCFCKAGYTGRHC 1513 Score = 48.0 bits (109), Expect = 1e-04 Identities = 18/39 (46%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G TG DC Sbjct: 1295 CGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGSDC 1333 Score = 47.2 bits (107), Expect = 2e-04 Identities = 18/39 (46%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C+D + + C CK G T KDC Sbjct: 1143 CGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTDKDC 1181 Score = 44.8 bits (101), Expect = 0.001 Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 1297 LNSYVAD--NG-TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 LNSY+ +G T C +C+SAPC NG C Y C CK G TGK+C Sbjct: 899 LNSYLCTCPSGYTGTKCEIVPDQCASAPCINGGTCKSDRYGYHCHCKVGFTGKNC 953 Score = 44.4 bits (100), Expect = 0.001 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S+PC NG C+D+ + + C C G+TG C Sbjct: 1627 CEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITC 1665 Score = 43.6 bits (98), Expect = 0.002 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S+PC NG C+D+ + + C C G+TG C Sbjct: 1665 CDIDIDECASSPCQNGGFCTDMINAFTCSCPPGYTGITC 1703 Score = 43.2 bits (97), Expect = 0.003 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S+PC NG C+D+ + + C C G+TG C Sbjct: 1703 CDINIDECASSPCQNGGFCTDMINAFTCTCLPGYTGITC 1741 Score = 43.2 bits (97), Expect = 0.003 Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+SAPC + + C DL + Y C C G++G++C Sbjct: 1779 CEVNIDECASAPCQHRSTCKDLINDYNCTCHPGYSGRNC 1817 Score = 42.3 bits (95), Expect = 0.005 Identities = 66/279 (23%), Positives = 92/279 (32%), Gaps = 32/279 (11%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C+ D C C + CV C C G G QC + C PC D Sbjct: 1551 CEVNIDECATKPCLNGATCVDQIAVYKCLCAPGYKGLQCQIDIDECASNPCQNNGYCEDL 1610 Query: 1567 TPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKEN 1623 GY C C PG++ + E C G C GY C+ + Sbjct: 1611 I-NGYYCFCTPGFSGIHCEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITCDIDI 1669 Query: 1624 GKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 +C C+ + + C C G +C+ +C P G C NA Sbjct: 1670 DECASSPCQNGGFCTD-MINAFTCSC-PPGYTGITCDINIDECASSPCQNGGFCTDMINA 1727 Query: 1681 Y-AEVTPN-SG--CEVVYDGCPRSFA--GGVWWPRTKFGV-ETITDCPPGSSGRATR-TC 1732 + P +G C++ D C GG+ K G+ E C G +G Sbjct: 1728 FTCTCLPGYTGITCDINIDDCASRPCQNGGI----CKDGINEFKCQCSAGFTGNLCEVNI 1783 Query: 1733 DETKDVPWQD----PDM---FNCTTATFYQLRKQLHKIE 1764 DE P Q D+ +NCT Y R H+I+ Sbjct: 1784 DECASAPCQHRSTCKDLINDYNCTCHPGYSGRNCEHEID 1822 Score = 39.9 bits (89), Expect = 0.029 Identities = 44/174 (25%), Positives = 61/174 (35%), Gaps = 32/174 (18%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C S C C ++ TCTC G G C + C PC D + + Sbjct: 1709 ECASSPCQNGGFCTDMINAFTCTCLPGYTGITCDINIDDCASRPCQNGGICKDGINE-FK 1767 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPC----AC-DVTRGYHPHCNKENGKCH 1627 C C G+T E +EC A PC C D+ Y+ C+ + Sbjct: 1768 CQCSAGFT---GNLCEVNIDEC--------ASAPCQHRSTCKDLINDYNCTCHPGYSGRN 1816 Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIGRACDACAN 1679 C+ EC+ C G C A G C C PG G+ C+ A+ Sbjct: 1817 CEHE------IDECISSPCRNKGY----CYDAIGYYLCICPPGFYGKHCENLAS 1860 Score = 38.7 bits (86), Expect = 0.066 Identities = 21/66 (31%), Positives = 25/66 (37%), Gaps = 5/66 (7%) Query: 1283 GCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEG 1342 G +D HK Y N C C++ PC NGA C D Y C C G Sbjct: 1529 GTCTDLVDAHKCQCSTGYTGKN-----CEVNIDECATKPCLNGATCVDQIAVYKCLCAPG 1583 Query: 1343 HTGKDC 1348 + G C Sbjct: 1584 YKGLQC 1589 Score = 38.7 bits (86), Expect = 0.066 Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD--STG 1353 C + C S+PC N C D Y+C C G GK C + STG Sbjct: 1817 CEHEIDECISSPCRNKGYCYDAIGYYLCICPPGFYGKHCENLASTG 1862 Score = 37.5 bits (83), Expect = 0.15 Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC N C DL + Y C C G +G C Sbjct: 1589 CQIDIDECASNPCQNNGYCEDLINGYYCFCTPGFSGIHC 1627 Score = 37.5 bits (83), Expect = 0.15 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 8/74 (10%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG-----SQCVARREGGILCQGCS 1093 + +FTC C G+TG+ C+ + + +G IC+ G QC A G LC+ + Sbjct: 1725 INAFTCTCLPGYTGITCDINIDDCASRPCQNGGICKDGINEFKCQCSAGFTGN-LCE-VN 1782 Query: 1094 IDAAYTTAVCELRA 1107 ID +A C+ R+ Sbjct: 1783 IDEC-ASAPCQHRS 1795 Score = 37.5 bits (83), Expect = 0.15 Identities = 14/32 (43%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S PC NG C D + + C C G TG C Sbjct: 1748 CASRPCQNGGICKDGINEFKCQCSAGFTGNLC 1779 Score = 37.1 bits (82), Expect = 0.20 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + +FTC CP G+TG+ C+ + + + S C++G C I CS Y Sbjct: 1649 INAFTCTCPPGYTGITCDIDIDECA------SSPCQNGGFCTDM----INAFTCSCPPGY 1698 Query: 1099 TTAVCEL 1105 T C++ Sbjct: 1699 TGITCDI 1705 Score = 36.3 bits (80), Expect = 0.35 Identities = 11/35 (31%), Positives = 20/35 (57%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073 + +FTC CP G+TG+ C+ + + + +G C Sbjct: 1687 INAFTCSCPPGYTGITCDINIDECASSPCQNGGFC 1721 Score = 35.1 bits (77), Expect = 0.82 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 8/90 (8%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-----REGGILCQ 1090 + FTC C GFTG +C T + + + + +G+ C +G +C + ++ G Sbjct: 1241 INGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFRCTCKPGFTGKDCGTEID 1300 Query: 1091 GCSIDAAYTTAVCELRARSFPVSSFLTFPG 1120 C+ + A C R F + F G Sbjct: 1301 ECASNPCKNGATCTDRINGFTCTCKPGFTG 1330 Score = 34.7 bits (76), Expect = 1.1 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 10/75 (13%) Query: 1011 EECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDG 1070 + C T + N+S N S R ++ FTC C GFTG +C T + + + + Sbjct: 951 KNCETNIDECNSSPCKNGGSCTDR----ISGFTCTCKHGFTGKDCGTEIDECASKP---- 1002 Query: 1071 SICRSGSQCVARREG 1085 C++G+ C R G Sbjct: 1003 --CKNGATCTDRING 1015 Score = 34.3 bits (75), Expect = 1.4 Identities = 12/37 (32%), Positives = 20/37 (54%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS 1075 + S+ C CP G+TG CE + + + +G C+S Sbjct: 899 LNSYLCTCPSGYTGTKCEIVPDQCASAPCINGGTCKS 935 Score = 34.3 bits (75), Expect = 1.4 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 6/44 (13%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 + C C GFTG NCET + + + S C++G C R G Sbjct: 940 YHCHCKVGFTGKNCETNIDEC------NSSPCKNGGSCTDRISG 977 Score = 33.9 bits (74), Expect = 1.9 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-----REGGILCQ 1090 + FTC C GFTG +C T + + + + +G+ C +G C + ++ G Sbjct: 1089 INGFTCACKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDCGTEID 1148 Query: 1091 GCSIDAAYTTAVCELRARSF 1110 C+ + A C R F Sbjct: 1149 ECASNPCKNGATCTDRINGF 1168 Score = 33.9 bits (74), Expect = 1.9 Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 8/90 (8%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-----REGGILCQ 1090 + FTC C GFTG +C T + + + +G+ C +G C + ++ G Sbjct: 1317 INGFTCTCKPGFTGSDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEID 1376 Query: 1091 GCSIDAAYTTAVCELRARSFPVSSFLTFPG 1120 C+ + A C R F + F G Sbjct: 1377 ECASNPCKNGATCTDRINGFACTCKPGFTG 1406 Score = 33.5 bits (73), Expect = 2.5 Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 6/47 (12%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 + FTC C GFTG +C T + + + + C++G+ C R G Sbjct: 1013 INGFTCTCKPGFTGSDCGTEIDECA------SNPCKNGATCTDRING 1053 Score = 33.5 bits (73), Expect = 2.5 Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 6/47 (12%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 + FTC C GFTG +C T + + + + C++G+ C R G Sbjct: 1051 INGFTCTCKPGFTGKDCGTEIDECASKP------CKNGATCTDRING 1091 Score = 33.5 bits (73), Expect = 2.5 Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 10/65 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + F C C GFTG +C T + + + E C++G+ C + G + C+ Y Sbjct: 1393 INGFACTCKPGFTGKDCGTEIDECASEP------CKNGANCTDKINGFM----CTCKEGY 1442 Query: 1099 TTAVC 1103 T C Sbjct: 1443 TGKDC 1447 >SB_32940| Best HMM Match : EGF (HMM E-Value=0) Length = 1025 Score = 58.8 bits (136), Expect = 6e-08 Identities = 45/174 (25%), Positives = 61/174 (35%), Gaps = 12/174 (6%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSC 1573 C S C S CV D+ C C G G C ++ C PC C+ GY C Sbjct: 441 CSSSPCENNSTCVNKLDTFKCFCTPGYTGSHCEVNINECASSPCQYGTCI--DLIDGYRC 498 Query: 1574 ACEPGYTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCHCK- 1629 C+PG+ T G E C G + CD GY HC ++ C + Sbjct: 499 YCKPGFGGTNCGLNLNECLSNPCYNGGFCVDEENNYRCDCGHGYRGRHCEEDVDLCKEEG 558 Query: 1630 --ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 N + + CQC G ++C C P + G C N + Sbjct: 559 WCVNAISCKDNGNSVDCQC-KPGFTGANCAVDIHDCVNNPCMNGGTCKDKVNDF 611 Score = 45.2 bits (102), Expect = 8e-04 Identities = 18/41 (43%), Positives = 23/41 (56%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 AG C+S+PC NG C D D+Y C CK+G G +C Sbjct: 118 AGSDIDEDECASSPCRNGGLCIDQVDSYKCSCKQGTFGLNC 158 Score = 45.2 bits (102), Expect = 8e-04 Identities = 17/41 (41%), Positives = 22/41 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C + C S PCYNG C D + Y CDC G+ G+ C + Sbjct: 509 CGLNLNECLSNPCYNGGFCVDEENNYRCDCGHGYRGRHCEE 549 Score = 44.0 bits (99), Expect = 0.002 Identities = 16/39 (41%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CSS+PC N + C + DT+ C C G+TG C Sbjct: 434 CDTELNACSSSPCENNSTCVNKLDTFKCFCTPGYTGSHC 472 Score = 41.9 bits (94), Expect = 0.007 Identities = 18/43 (41%), Positives = 21/43 (48%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T A C C + PC NG C D + + C CK G TGK C Sbjct: 582 TGANCAVDIHDCVNNPCMNGGTCKDKVNDFECFCKPGFTGKTC 624 Score = 41.1 bits (92), Expect = 0.012 Identities = 45/168 (26%), Positives = 59/168 (35%), Gaps = 17/168 (10%) Query: 1522 CPPYSKCVTSWDSST--CTCEAGRVGPQCVSA--CELGPC--GAARCVPDQTPKG-YSCA 1574 C + +CVT++ S+ C C G G C C PC GA + P+ Y+C Sbjct: 327 CSNHGQCVTNFSMSSYQCKCCGGFRGEFCEKEDHCFSKPCKNGATCKNKEGDPRHFYTCT 386 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA----CDVTRGY-HPHCNKENGKCHCK 1629 C PGY + P +AC P C RGY C+ E C Sbjct: 387 CAPGYEGRDCSRVIDMCVSNPCKL--NAACTPLVNDFHCSCPRGYTGKTCDTELNACSSS 444 Query: 1630 --ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 EN+ + C C G S CE +C P G D Sbjct: 445 PCENNSTCVNKLDTFKCFC-TPGYTGSHCEVNINECASSPCQYGTCID 491 Score = 40.3 bits (90), Expect = 0.022 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 4/42 (9%) Query: 1312 EKRSRCSSAPCYNGAEC----SDLWDTYICDCKEGHTGKDCA 1349 EK C S PC NGA C D Y C C G+ G+DC+ Sbjct: 356 EKEDHCFSKPCKNGATCKNKEGDPRHFYTCTCAPGYEGRDCS 397 Score = 38.7 bits (86), Expect = 0.066 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S+PC G C DL D Y C CK G G +C Sbjct: 472 CEVNINECASSPCQYGT-CIDLIDGYRCYCKPGFGGTNC 509 Score = 37.9 bits (84), Expect = 0.12 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C S PC A C+ L + + C C G+TGK C Sbjct: 396 CSRVIDMCVSNPCKLNAACTPLVNDFHCSCPRGYTGKTC 434 Score = 36.7 bits (81), Expect = 0.27 Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V F C CP G+TG C+T L S S C + S CV + + C Y Sbjct: 418 VNDFHCSCPRGYTGKTCDTELNACS------SSPCENNSTCVNKLD----TFKCFCTPGY 467 Query: 1099 TTAVCEL 1105 T + CE+ Sbjct: 468 TGSHCEV 474 Score = 36.3 bits (80), Expect = 0.35 Identities = 13/32 (40%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C PC NG CS ++CDC +G+ G C Sbjct: 53 CLPNPCTNGGLCSVNGTNFLCDCPQGYRGDRC 84 Score = 34.3 bits (75), Expect = 1.4 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 4/73 (5%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPG 1578 C C + +S C C+ G G C + C PC D+ + C C+PG Sbjct: 560 CVNAISCKDNGNSVDCQCKPGFTGANCAVDIHDCVNNPCMNGGTCKDKV-NDFECFCKPG 618 Query: 1579 YTLTTSGCIESGK 1591 +T T ++ + Sbjct: 619 FTGKTCELLDGSR 631 Score = 33.9 bits (74), Expect = 1.9 Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 1310 CPEKRSRCSSAP-CYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C E C C N C D ++ C CK G TG +CA Sbjct: 547 CEEDVDLCKEEGWCVNAISCKDNGNSVDCQCKPGFTGANCA 587 >SB_58558| Best HMM Match : EGF (HMM E-Value=0) Length = 1101 Score = 58.0 bits (134), Expect = 1e-07 Identities = 44/167 (26%), Positives = 54/167 (32%), Gaps = 10/167 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQTPKGYS 1572 DC + C + C+ +S TC C G G QC C+ PC DQ GY Sbjct: 582 DCASTPCMNGATCLDGVNSYTCICVTGWTGDQCTINPDNCQSAPCQNNGTCTDQV-NGYL 640 Query: 1573 CACEPGY--TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKENGKCHCK 1629 C C PG+ E C G G C GY HC + +C Sbjct: 641 CDCTPGWYGKACEHDVDECSSNPCVNGGTCNDEAGGYTCTCAAGYTGLHCETDIDECRTN 700 Query: 1630 E--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 N C C A G CE C +P + G C Sbjct: 701 PCLNGATCTDKVNSYTCTC-APGYAGVHCEKDEDDCASKPCLNGGTC 746 Score = 57.6 bits (133), Expect = 1e-07 Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 21/185 (11%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C+ AD C C C D+ CTC G G +C ++ C+ PC D+ Sbjct: 500 CEINADDCQSMPCLNGGSCKDKVDAYECTCPLGYTGLRCETDINDCQPNPCLNGGSCTDR 559 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPG-GWWGGSAC------GPCACDVTRGYHPHC 1619 GY+CAC PGY T + C E ++C G+ C C C VT C Sbjct: 560 V-NGYTCACAPGY--TGNNC-EKDIDDCASTPCMNGATCLDGVNSYTCIC-VTGWTGDQC 614 Query: 1620 NKENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676 C C+ N + L C C G +CE +C P V G C+ Sbjct: 615 TINPDNCQSAPCQNNGTCTDQVNGYL-CDC-TPGWYGKACEHDVDECSSNPCVNGGTCND 672 Query: 1677 CANAY 1681 A Y Sbjct: 673 EAGGY 677 Score = 54.0 bits (124), Expect = 2e-06 Identities = 59/231 (25%), Positives = 80/231 (34%), Gaps = 36/231 (15%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C C + C +++ TCTC AG G C + C C CV GY Sbjct: 239 ECAPQPCKNGATCNNLFNNYTCTCAAGYTGINCTENIDDCNGVVCQNGGNCV--DGVNGY 296 Query: 1572 SCACEPGYTLTTSGCIESGKEECP-GGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 C+C PGY T S C E+ EC G C D+ G+ C C+ Sbjct: 297 KCSCAPGY--TGSNC-ETDINECAVNSCQNGGNC----TDLVNGFSCTCAPGYTGHRCET 349 Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN-AYAEVTPNSG 1689 + +C C G+ +C C G +G C N + N G Sbjct: 350 D------IDDCASAPCRNGGTCTDQVNGY--RCQCALGFVGSYCQINVNDCIPDPCQNGG 401 Query: 1690 ---CEVVYDG---CPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDE 1734 C++V D CP + G K E I DC P G D+ Sbjct: 402 FCCCDLVNDWICLCPGGWGG-------KNCTENINDCDPNPCGNGGTCTDQ 445 Score = 49.6 bits (113), Expect = 4e-05 Identities = 17/42 (40%), Positives = 26/42 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 C E C+ PC NGA C++L++ Y C C G+TG +C ++ Sbjct: 233 CTEDVDECAPQPCKNGATCNNLFNNYTCTCAAGYTGINCTEN 274 Score = 48.4 bits (110), Expect = 8e-05 Identities = 57/239 (23%), Positives = 82/239 (34%), Gaps = 25/239 (10%) Query: 1500 RPTVRENVRDGC--QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL 1554 R +R N C Q DC S C C ++ C C G VG C ++ C Sbjct: 144 RYEIRRNSEYYCYLQGIDDCAPSPCRNNGTCTDMHNAYRCQCTQGFVGKNCQININDCIP 203 Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTR 1613 PC C D + C C G+ T C E E P G+ C ++ Sbjct: 204 DPCQNGGWCCCDLV-NDWICQCPKGW--TGKNCTEDVDECAPQPCKNGATCN----NLFN 256 Query: 1614 GYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGR 1672 Y C +C EN +C C G + + G +C C PG G Sbjct: 257 NYTCTCAAGYTGINCTEN------IDDCNGVVCQNGG---NCVDGVNGYKCSCAPGYTGS 307 Query: 1673 ACDACANAYAEVTPNSG--CEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRAT 1729 C+ N A + +G C + +G + A G R + ++ P + G T Sbjct: 308 NCETDINECAVNSCQNGGNCTDLVNGFSCTCAPGYTGHRCETDIDDCASAPCRNGGTCT 366 Score = 48.4 bits (110), Expect = 8e-05 Identities = 42/164 (25%), Positives = 58/164 (35%), Gaps = 20/164 (12%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC + C C ++ CTC G G +C ++ C PC DQ GY+ Sbjct: 430 DCDPNPCGNGGTCTDQLNAYLCTCPPGYTGSKCEIDINECASFPCQNGGSCTDQV-NGYT 488 Query: 1573 CACEPGYTLTTSGCIESGKEECPG-GWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631 C+C GY + C E ++C G +C D Y C C+ + Sbjct: 489 CSCAAGY--SGVNC-EINADDCQSMPCLNGGSCK----DKVDAYECTCPLGYTGLRCETD 541 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 +C P C GS T C C PG G C+ Sbjct: 542 ------INDCQPNPCLNGGSCTDRVNGYT--CACAPGYTGNNCE 577 Score = 48.4 bits (110), Expect = 8e-05 Identities = 45/176 (25%), Positives = 57/176 (32%), Gaps = 14/176 (7%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC + C C + TC C G G C + C PC A C+ Y Sbjct: 544 DCQPNPCLNGGSCTDRVNGYTCACAPGYTGNNCEKDIDDCASTPCMNGATCLDGVN--SY 601 Query: 1572 SCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 +C C G+T T C CD T G++ E+ C Sbjct: 602 TCICVTGWTGDQCTINPDNCQSAPCQNNGTCTDQVNGYLCDCTPGWYGKAC-EHDVDECS 660 Query: 1630 ENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 N GT A C C AAG CE +C P + G C N+Y Sbjct: 661 SNPCVNGGTCNDEAGGYTCTC-AAGYTGLHCETDIDECRTNPCLNGATCTDKVNSY 715 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C PC NG C+D + Y+C C G+TG C Sbjct: 424 CTENINDCDPNPCGNGGTCTDQLNAYLCTCPPGYTGSKC 462 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/39 (43%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C SAPC N C+D + Y+CDC G GK C Sbjct: 614 CTINPDNCQSAPCQNNGTCTDQVNGYLCDCTPGWYGKAC 652 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/39 (43%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C S PC NG C D D Y C C G+TG C Sbjct: 500 CEINADDCQSMPCLNGGSCKDKVDAYECTCPLGYTGLRC 538 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/39 (43%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C CSS PC NG C+D Y C C G+TG C Sbjct: 652 CEHDVDECSSNPCVNGGTCNDEAGGYTCTCAAGYTGLHC 690 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/41 (41%), Positives = 21/41 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C + C+S PC NG C+DL + C C G GK C D Sbjct: 728 CEKDEDDCASKPCLNGGTCTDLLADFECACVLGFIGKTCND 768 Score = 42.7 bits (96), Expect = 0.004 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NG C+D + Y C C G++G +C Sbjct: 462 CEIDINECASFPCQNGGSCTDQVNGYTCSCAAGYSGVNC 500 Score = 42.7 bits (96), Expect = 0.004 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC NGA C D ++Y C C G TG C Sbjct: 576 CEKDIDDCASTPCMNGATCLDGVNSYTCICVTGWTGDQC 614 Score = 42.3 bits (95), Expect = 0.005 Identities = 13/32 (40%), Positives = 20/32 (62%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ +PC N C+D+ + Y C C +G GK+C Sbjct: 163 CAPSPCRNNGTCTDMHNAYRCQCTQGFVGKNC 194 Score = 41.9 bits (94), Expect = 0.007 Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C PC NG C+D + Y C C G+TG +C Sbjct: 538 CETDINDCQPNPCLNGGSCTDRVNGYTCACAPGYTGNNC 576 Score = 41.9 bits (94), Expect = 0.007 Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C + PC NGA C+D ++Y C C G+ G C Sbjct: 690 CETDIDECRTNPCLNGATCTDKVNSYTCTCAPGYAGVHC 728 Score = 41.5 bits (93), Expect = 0.009 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 10/74 (13%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 ++TC C G+TG+NC + D +G +C++G CV G+ CS YT Sbjct: 257 NYTCTCAAGYTGINCTENID------DCNGVVCQNGGNCV----DGVNGYKCSCAPGYTG 306 Query: 1101 AVCELRARSFPVSS 1114 + CE V+S Sbjct: 307 SNCETDINECAVNS 320 Score = 41.5 bits (93), Expect = 0.009 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 T + C + C+ C NG C+DL + + C C G+TG C D P R GG Sbjct: 305 TGSNCETDINECAVNSCQNGGNCTDLVNGFSCTCAPGYTGHRCETDIDDCASAPCRNGG 363 Score = 40.3 bits (90), Expect = 0.022 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E C+ C NG C D + Y C C G+TG +C Sbjct: 271 CTENIDDCNGVVCQNGGNCVDGVNGYKCSCAPGYTGSNC 309 Score = 39.9 bits (89), Expect = 0.029 Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCAD 1350 C + C PC NG C DL + +IC C +G TGK+C + Sbjct: 194 CQININDCIPDPCQNGGWCCCDLVNDWICQCPKGWTGKNCTE 235 Score = 39.9 bits (89), Expect = 0.029 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+SAPC NG C+D + Y C C G G C Sbjct: 347 CETDIDDCASAPCRNGGTCTDQVNGYRCQCALGFVGSYC 385 Score = 35.5 bits (78), Expect = 0.62 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V + C C G+TG NCET + + C V+ C++G C G C+ Y Sbjct: 293 VNGYKCSCAPGYTGSNCETDINE--CAVNS----CQNGGNCTDLVNG----FSCTCAPGY 342 Query: 1099 TTAVCE 1104 T CE Sbjct: 343 TGHRCE 348 Score = 35.5 bits (78), Expect = 0.62 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 10/69 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + ++ C CP G+TG CE + + + C++G C + G CS A Y Sbjct: 446 LNAYLCTCPPGYTGSKCEIDINECA------SFPCQNGGSCTDQVNG----YTCSCAAGY 495 Query: 1099 TTAVCELRA 1107 + CE+ A Sbjct: 496 SGVNCEINA 504 Score = 35.5 bits (78), Expect = 0.62 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V ++ C CP G+TG+ CET + D + C +G C R G C+ Y Sbjct: 522 VDAYECTCPLGYTGLRCETDIN------DCQPNPCLNGGSCTDRVNG----YTCACAPGY 571 Query: 1099 TTAVCE 1104 T CE Sbjct: 572 TGNNCE 577 Score = 34.7 bits (76), Expect = 1.1 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCADS 1351 C + C PC NG C DL + +IC C G GK+C ++ Sbjct: 385 CQINVNDCIPDPCQNGGFCCCDLVNDWICLCPGGWGGKNCTEN 427 Score = 33.1 bits (72), Expect = 3.3 Identities = 12/37 (32%), Positives = 22/37 (59%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS 1075 V + CQCP+G+TG NC + + + + +G+ C + Sbjct: 217 VNDWICQCPKGWTGKNCTEDVDECAPQPCKNGATCNN 253 Score = 33.1 bits (72), Expect = 3.3 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V F+C C G+TG CET + D + CR+G C + G CQ C++ + Sbjct: 331 VNGFSCTCAPGYTGHRCETDID------DCASAPCRNGGTC-TDQVNGYRCQ-CAL--GF 380 Query: 1099 TTAVCEL 1105 + C++ Sbjct: 381 VGSYCQI 387 Score = 32.7 bits (71), Expect = 4.4 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V +TC C G++GVNCE + C+ C +G C + + C+ Y Sbjct: 484 VNGYTCSCAAGYSGVNCE--INADDCQ----SMPCLNGGSC----KDKVDAYECTCPLGY 533 Query: 1099 TTAVCE 1104 T CE Sbjct: 534 TGLRCE 539 Score = 32.7 bits (71), Expect = 4.4 Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 V +TC C G+TG NCE + + +G+ C G Sbjct: 560 VNGYTCACAPGYTGNNCEKDIDDCASTPCMNGATCLDG 597 >SB_20112| Best HMM Match : EGF (HMM E-Value=0) Length = 2112 Score = 58.0 bits (134), Expect = 1e-07 Identities = 53/205 (25%), Positives = 74/205 (36%), Gaps = 28/205 (13%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C++ D C C + C + + TCTC AG G C ++ C PC C+ Sbjct: 795 CRTNIDECAKGPCKYGATCHDAVANYTCTCTAGFTGKNCDININECASNPCQRGSCL--D 852 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625 GY C+C GY C E ++C + G +C D + C Sbjct: 853 LVNGYLCSCPKGY--IGKHC-EVNADDCFVNACFNGGSC----VDGIAEFKCTCPLGFSG 905 Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685 C+ + EC C A G+E C C+ G +GR CD N Sbjct: 906 SRCEVD------VDECASSPCSALGTEKCINNIGAYHCQCKQGFLGRHCDLNINECLSYP 959 Query: 1686 PNSGCEVVYDG-------CPRSFAG 1703 +G E DG CP F+G Sbjct: 960 CRNGGE-CKDGAGEYTCLCPHGFSG 983 Score = 57.6 bits (133), Expect = 1e-07 Identities = 51/181 (28%), Positives = 68/181 (37%), Gaps = 24/181 (13%) Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVP 1564 D CQ D C S C C+ ++ TC C G GP+C ++ C PC Sbjct: 636 DRCQINVDDCQSSPCVHGGSCIDGINTYTCQCPKGFTGPRCEIHINECSSDPCQHGGTCS 695 Query: 1565 DQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHC--NK 1621 D+ YSC C PGY T S C + + C G+ C D++ +H C Sbjct: 696 DRI-GSYSCYCRPGY--TGSNC-QHPLDRCANDPCRNGATCRRTGEDLS-DFHCECPLGY 750 Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC----DAC 1677 + C KE GT C+ + S C C+PG G C D C Sbjct: 751 KGTICDVKEVSCAVAGTICANGGTCFDSNGVQS--------CTCKPGFTGSYCRTNIDEC 802 Query: 1678 A 1678 A Sbjct: 803 A 803 Score = 47.6 bits (108), Expect = 1e-04 Identities = 45/168 (26%), Positives = 56/168 (33%), Gaps = 20/168 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C S C C C C G G C + +C C A CV TP Y Sbjct: 530 ECASSPCRNGGTCEDGVAQYYCRCRDGYTGKNCEVRIDSCIDHTCQNGASCV-SSTPYAY 588 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631 SC C+PGY T E+ +EC AC D G+ C+ C+ N Sbjct: 589 SCQCKPGY---TGQYCETDVDECAARPCVNGAC----VDGVNGFICRCDPGFTGDRCQIN 641 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 +C C GS T C C G G C+ N Sbjct: 642 ------VDDCQSSPCVHGGSCIDGINTYT--CQCPKGFTGPRCEIHIN 681 Score = 47.2 bits (107), Expect = 2e-04 Identities = 17/39 (43%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S+PC NG C D Y C C++G+TGK+C Sbjct: 524 CGVPVNECASSPCRNGGTCEDGVAQYYCRCRDGYTGKNC 562 Score = 46.8 bits (106), Expect = 3e-04 Identities = 18/41 (43%), Positives = 22/41 (53%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A C E + C S PC NG C D+ + Y CDC GK+C Sbjct: 1060 ANCEESINECLSQPCKNGGSCRDIVNGYKCDCPSKMIGKNC 1100 Score = 46.0 bits (104), Expect = 4e-04 Identities = 46/197 (23%), Positives = 68/197 (34%), Gaps = 20/197 (10%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC + C C+ ++ +C C G G C V+ C PC D + Y Sbjct: 492 DCPANACQNGGVCIDGMNTYSCKCHPGFTGFSCGVPVNECASSPCRNGGTCEDGVAQ-YY 550 Query: 1573 CACEPGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC 1626 C C GYT + CI+ + G S +C GY +C + +C Sbjct: 551 CRCRDGYTGKNCEVRIDSCIDHTCQN--GASCVSSTPYAYSCQCKPGYTGQYCETDVDEC 608 Query: 1627 HCKE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV 1684 + N +G + C+C G C+ C P V G +C N Y Sbjct: 609 AARPCVNGACVDGVNGFI-CRC-DPGFTGDRCQINVDDCQSSPCVHGGSCIDGINTYTCQ 666 Query: 1685 TPNS----GCEVVYDGC 1697 P CE+ + C Sbjct: 667 CPKGFTGPRCEIHINEC 683 Score = 45.2 bits (102), Expect = 8e-04 Identities = 17/39 (43%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + CSS PC +G CSD +Y C C+ G+TG +C Sbjct: 676 CEIHINECSSDPCQHGGTCSDRIGSYSCYCRPGYTGSNC 714 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/42 (40%), Positives = 22/42 (52%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 C + C SAPC NG C D + +Y C C G G +C +S Sbjct: 1024 CEWNKDECLSAPCRNGGTCIDGYGSYSCKCPLGFAGANCEES 1065 Score = 44.4 bits (100), Expect = 0.001 Identities = 56/230 (24%), Positives = 81/230 (35%), Gaps = 30/230 (13%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C + C+ + C C G G C ++ C+ PC +C Y Sbjct: 303 ECESNPCV-HGLCLDYQNKFECACSKGYTGRLCDVEINECDSNPCLNGGQC--HDGLGNY 359 Query: 1572 SCACEPGYT--LTTSGCIESGKEECP--GGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627 SC C+ GY + + + C G G A C C + G+ + N Sbjct: 360 SCTCQVGYVGEICQTNYDDCASNPCQNDGTCQDGIAQYTCLCPL--GFTGKSCETNTN-E 416 Query: 1628 CKENHYKPEGTA----ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAE 1683 C N GT CQC G + CE +C P G C N Y Sbjct: 417 CAGNPCMNMGTCIDGINSFRCQC-PLGFTGNRCETEIDECESSPCQNGGTCKDKINGYVC 475 Query: 1684 VTP----NSGCEVVYDGCPRSFA--GGVWWPRTKFGVETIT-DCPPGSSG 1726 + P + CE + CP + GGV G+ T + C PG +G Sbjct: 476 ICPPGASGTHCENDPNDCPANACQNGGVCID----GMNTYSCKCHPGFTG 521 Score = 43.6 bits (98), Expect = 0.002 Identities = 50/193 (25%), Positives = 64/193 (33%), Gaps = 23/193 (11%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPCGA-ARCVPDQTPKGYSCACEPG 1578 C CV S TC C G+ G C C PC A CV + K SC C G Sbjct: 193 CQHGGTCVDKIGSYTCICPPGKTGLICNFDDECASNPCSENATCVTSFSGKA-SCICNSG 251 Query: 1579 YTLTTSGCIESGKEECPGG---WWGGSAC----GPCACDVTRGY-HPHCNKENGKCHCKE 1630 + T C + +EC G + G C G CD G+ C +C Sbjct: 252 W--TGKNC-DVDIKECEGDSSPCYHGGTCRDIPGSFVCDCVPGFAGARCEDNINECESNP 308 Query: 1631 -NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689 H C C + G C+ +C P + G C Y+ T G Sbjct: 309 CVHGLCLDYQNKFECAC-SKGYTGRLCDVEINECDSNPCLNGGQCHDGLGNYS-CTCQVG 366 Query: 1690 -----CEVVYDGC 1697 C+ YD C Sbjct: 367 YVGEICQTNYDDC 379 Score = 43.2 bits (97), Expect = 0.003 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 K S+PCY+G C D+ +++CDC G G C D+ Sbjct: 262 KECEGDSSPCYHGGTCRDIPGSFVCDCVPGFAGARCEDN 300 Score = 42.3 bits (95), Expect = 0.005 Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S+PC NG C D + Y+C C G +G C Sbjct: 448 CETEIDECESSPCQNGGTCKDKINGYVCICPPGASGTHC 486 Score = 42.3 bits (95), Expect = 0.005 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 7/63 (11%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DGMLSFNPL 1369 C S+PC +G C D +TY C C +G TG C + + P + GG D + S++ Sbjct: 645 CQSSPCVHGGSCIDGINTYTCQCPKGFTGPRCEIHINECSSDPCQHGGTCSDRIGSYSCY 704 Query: 1370 LRP 1372 RP Sbjct: 705 CRP 707 Score = 41.9 bits (94), Expect = 0.007 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C S PC NG +C D Y C C+ G+ G+ C Sbjct: 334 CDVEINECDSNPCLNGGQCHDGLGNYSCTCQVGYVGEIC 372 Score = 41.9 bits (94), Expect = 0.007 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC--RSGSQCVARREG--GILCQ---- 1090 + ++TCQCP+GFTG CE + + S + G C R GS R G G CQ Sbjct: 660 INTYTCQCPKGFTGPRCEIHINECSSDPCQHGGTCSDRIGSYSCYCRPGYTGSNCQHPLD 719 Query: 1091 GCSIDAAYTTAVC 1103 C+ D A C Sbjct: 720 RCANDPCRNGATC 732 Score = 41.9 bits (94), Expect = 0.007 Identities = 16/39 (41%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+ PC GA C D Y C C G TGK+C Sbjct: 795 CRTNIDECAKGPCKYGATCHDAVANYTCTCTAGFTGKNC 833 Score = 41.9 bits (94), Expect = 0.007 Identities = 17/39 (43%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC NG EC D Y C C G +G DC Sbjct: 948 CDLNINECLSYPCRNGGECKDGAGEYTCLCPHGFSGDDC 986 Score = 41.5 bits (93), Expect = 0.009 Identities = 60/226 (26%), Positives = 81/226 (35%), Gaps = 35/226 (15%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC---GAARCVPDQTPK 1569 +C+ C +C TC C G G C V C PC G R V + Sbjct: 954 ECLSYPCRNGGECKDGAGEYTCLCPHGFSGDDCERRVYTCSDQPCLNSGTCRTVHNT--- 1010 Query: 1570 GYSCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHC 1628 Y+C+C PG + C E K+EC G C D Y C +C Sbjct: 1011 -YNCSCRPG--VYGKQC-EWNKDECLSAPCRNGGTC----IDGYGSYSCKCPLGFAGANC 1062 Query: 1629 KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNS 1688 +E+ ECL C GS +C C +IG+ C+ V PN Sbjct: 1063 EES------INECLSQPCKNGGSCRDIVNGY--KCDCPSKMIGKNCETVVKDQCPV-PN- 1112 Query: 1689 GCEVVYDG--C-PRSFAGGVWWPRT--KFGVETITDCPP-GSSGRA 1728 C +DG C P+ W T G+E ++C SG+A Sbjct: 1113 -CAKKFDGGKCNPKCNTHECNWDGTTCSLGIEPWSNCTTVTKSGKA 1157 Score = 41.1 bits (92), Expect = 0.012 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC G+ C DL + Y+C C +G+ GK C Sbjct: 833 CDININECASNPCQRGS-CLDLVNGYLCSCPKGYIGKHC 870 Score = 41.1 bits (92), Expect = 0.012 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + CS PC N C + +TY C C+ G GK C Sbjct: 986 CERRVYTCSDQPCLNSGTCRTVHNTYNCSCRPGVYGKQC 1024 Score = 40.3 bits (90), Expect = 0.022 Identities = 47/196 (23%), Positives = 69/196 (35%), Gaps = 25/196 (12%) Query: 1513 SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPK 1569 ++ +C+ + C C+ + S +C C G G C ++ C PC D Sbjct: 1027 NKDECLSAPCRNGGTCIDGYGSYSCKCPLGFAGANCEESINECLSQPCKNGGSCRD-IVN 1085 Query: 1570 GYSCACEPGYTLTTSGCIESGKEECP----GGWWGGSACGPCACDVTRGYHPHCNKENGK 1625 GY C C + C K++CP + G C P C+ H CN + Sbjct: 1086 GYKCDCPS--KMIGKNCETVVKDQCPVPNCAKKFDGGKCNP-KCNT----H-ECNWDGTT 1137 Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQC-----HCRPGVIGRACDA-C 1677 C + T CY + N C E TG C C+P V D C Sbjct: 1138 CSLGIEPWSNCTTVTKSGKACYQVFA-NGVCDRECNTGGCLFDGFDCKPSVPKCGADKYC 1196 Query: 1678 ANAYAEVTPNSGCEVV 1693 A +A ++ C V Sbjct: 1197 AARFANAECDAICNNV 1212 Score = 39.9 bits (89), Expect = 0.029 Identities = 17/43 (39%), Positives = 19/43 (44%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C C+S PC N C D Y C C G TGK C +T Sbjct: 372 CQTNYDDCASNPCQNDGTCQDGIAQYTCLCPLGFTGKSCETNT 414 Score = 39.5 bits (88), Expect = 0.038 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 6/47 (12%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 + SF CQCP GFTG CET + + CE S C++G C + G Sbjct: 432 INSFRCQCPLGFTGNRCETEIDE--CE----SSPCQNGGTCKDKING 472 Score = 39.1 bits (87), Expect = 0.050 Identities = 14/31 (45%), Positives = 19/31 (61%) Query: 1319 SAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 S PC NG CS+++ Y+C C G G DC+ Sbjct: 148 SQPCQNGGTCSNVYGGYMCRCITGWDGADCS 178 Score = 39.1 bits (87), Expect = 0.050 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 16/89 (17%) Query: 1002 CVHEPCLNFEECLTVLKFGNAS---GFV------NSDSVLFRP-------IYPVTSFTCQ 1045 C +PCLN C TV N S G N D L P I S++C+ Sbjct: 993 CSDQPCLNSGTCRTVHNTYNCSCRPGVYGKQCEWNKDECLSAPCRNGGTCIDGYGSYSCK 1052 Query: 1046 CPEGFTGVNCETILTKASCEVDGDGSICR 1074 CP GF G NCE + + + +G CR Sbjct: 1053 CPLGFAGANCEESINECLSQPCKNGGSCR 1081 Score = 38.7 bits (86), Expect = 0.066 Identities = 41/176 (23%), Positives = 62/176 (35%), Gaps = 21/176 (11%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570 CQ+ C +C+T WD + C+ +C C D+ Sbjct: 151 CQNGGTCSNVYGGYMCRCITGWDGADCSVNI----DECKQNDPFPRCQHGGTCVDKI-GS 205 Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSA-C-----GPCACDVTRGY-HPHCNKEN 1623 Y+C C PG T G I + +EC +A C G +C G+ +C+ + Sbjct: 206 YTCICPPGKT----GLICNFDDECASNPCSENATCVTSFSGKASCICNSGWTGKNCDVDI 261 Query: 1624 GKCHCKENHYKPEGTAECLP----CQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 +C + GT +P C C G + CE +C P V G D Sbjct: 262 KECEGDSSPCYHGGTCRDIPGSFVCDC-VPGFAGARCEDNINECESNPCVHGLCLD 316 Score = 38.7 bits (86), Expect = 0.066 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C + C + C NG C D +TY C C G TG C + P R GG Sbjct: 486 CENDPNDCPANACQNGGVCIDGMNTYSCKCHPGFTGFSCGVPVNECASSPCRNGG 540 Score = 37.9 bits (84), Expect = 0.12 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A C + + C S PC +G C D + + C C +G+TG+ C Sbjct: 295 ARCEDNINECESNPCVHGL-CLDYQNKFECACSKGYTGRLC 334 Score = 37.9 bits (84), Expect = 0.12 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 9/66 (13%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V + C+C +G+TG NCE + SC +D C++G+ CV+ CQ C Y Sbjct: 546 VAQYYCRCRDGYTGKNCEVRID--SC-ID---HTCQNGASCVSSTPYAYSCQ-CK--PGY 596 Query: 1099 TTAVCE 1104 T CE Sbjct: 597 TGQYCE 602 Score = 37.9 bits (84), Expect = 0.12 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 9/83 (10%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQ-GCSIDAA 1097 + S++C C G+TG NC+ L + C D CR+G+ C RR G L C Sbjct: 698 IGSYSCYCRPGYTGSNCQHPLDR--CANDP----CRNGATC--RRTGEDLSDFHCECPLG 749 Query: 1098 YTTAVCELRARSFPVSSFLTFPG 1120 Y +C+++ S V+ + G Sbjct: 750 YKGTICDVKEVSCAVAGTICANG 772 Score = 37.9 bits (84), Expect = 0.12 Identities = 35/123 (28%), Positives = 45/123 (36%), Gaps = 14/123 (11%) Query: 1509 DGCQSRA-DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563 D C+ R C C C T ++ C+C G G QC C PC C+ Sbjct: 984 DDCERRVYTCSDQPCLNSGTCRTVHNTYNCSCRPGVYGKQCEWNKDECLSAPCRNGGTCI 1043 Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC-NKE 1622 YSC C G+ + C ES E G +C D+ GY C +K Sbjct: 1044 DGY--GSYSCKCPLGF--AGANCEESINECLSQPCKNGGSCR----DIVNGYKCDCPSKM 1095 Query: 1623 NGK 1625 GK Sbjct: 1096 IGK 1098 Score = 37.1 bits (82), Expect = 0.20 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 1/47 (2%) Query: 1303 DNGTLAGCPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348 D T C + C C NGA C S Y C CK G+TG+ C Sbjct: 555 DGYTGKNCEVRIDSCIDHTCQNGASCVSSTPYAYSCQCKPGYTGQYC 601 Score = 36.7 bits (81), Expect = 0.27 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C++ PC NGA C D + +IC C G TG C Sbjct: 601 CETDVDECAARPCVNGA-CVDGVNGFICRCDPGFTGDRC 638 Score = 35.9 bits (79), Expect = 0.47 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 10/71 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + +++C+C GFTG +C + + + S CR+G C E G+ C Y Sbjct: 508 MNTYSCKCHPGFTGFSCGVPVNECA------SSPCRNGGTC----EDGVAQYYCRCRDGY 557 Query: 1099 TTAVCELRARS 1109 T CE+R S Sbjct: 558 TGKNCEVRIDS 568 Score = 35.9 bits (79), Expect = 0.47 Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 5/53 (9%) Query: 1300 YVADNGTLAGCPEKRSRCSSAPCYNGAEC----SDLWDTYICDCKEGHTGKDC 1348 Y T + C RC++ PC NGA C DL D + C+C G+ G C Sbjct: 704 YCRPGYTGSNCQHPLDRCANDPCRNGATCRRTGEDLSD-FHCECPLGYKGTIC 755 Score = 35.1 bits (77), Expect = 0.82 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+ PC N C D +++ C C G TG C Sbjct: 410 CETNTNECAGNPCMNMGTCIDGINSFRCQCPLGFTGNRC 448 Score = 33.9 bits (74), Expect = 1.9 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + +TC CP GFTG +CET + + G+ C + C+ GI C + Sbjct: 394 IAQYTCLCPLGFTGKSCETNTNECA------GNPCMNMGTCI----DGINSFRCQCPLGF 443 Query: 1099 TTAVCE 1104 T CE Sbjct: 444 TGNRCE 449 Score = 32.7 bits (71), Expect = 4.4 Identities = 15/44 (34%), Positives = 17/44 (38%) Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 GT+ E + C NG C D C CK G TG C Sbjct: 752 GTICDVKEVSCAVAGTICANGGTCFDSNGVQSCTCKPGFTGSYC 795 Score = 32.7 bits (71), Expect = 4.4 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 11/69 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V ++TC C GFTG NC+ + + + + C+ GS C+ G + CS Y Sbjct: 817 VANYTCTCTAGFTGKNCDININECA------SNPCQRGS-CLDLVNGYL----CSCPKGY 865 Query: 1099 TTAVCELRA 1107 CE+ A Sbjct: 866 IGKHCEVNA 874 Score = 31.9 bits (69), Expect = 7.6 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 8/45 (17%) Query: 1039 VTSFT----CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079 VTSF+ C C G+TG NC+ + E +GD S C G C Sbjct: 237 VTSFSGKASCICNSGWTGKNCDVDIK----ECEGDSSPCYHGGTC 277 Score = 31.9 bits (69), Expect = 7.6 Identities = 14/55 (25%), Positives = 27/55 (49%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSID 1095 +++CQC G+TG CET + + + +G+ + + R + G C I+ Sbjct: 587 AYSCQCKPGYTGQYCETDVDECAARPCVNGACVDGVNGFICRCDPGFTGDRCQIN 641 Score = 31.9 bits (69), Expect = 7.6 Identities = 20/67 (29%), Positives = 27/67 (40%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V F C+C GFTG C+ + C+ S C G C+ GI C + Sbjct: 622 VNGFICRCDPGFTGDRCQ--INVDDCQ----SSPCVHGGSCI----DGINTYTCQCPKGF 671 Query: 1099 TTAVCEL 1105 T CE+ Sbjct: 672 TGPRCEI 678 >SB_18364| Best HMM Match : Cadherin (HMM E-Value=3e-12) Length = 104 Score = 57.2 bits (132), Expect = 2e-07 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 5/94 (5%) Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRL 225 D PV A + A+D D+GAN + Y+I G F I DS SG +S+ L Y+Q +Y + Sbjct: 5 DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGAISVAGRLSYKQRNNYSV 62 Query: 226 VIRAQDGGSPSRSNTTQLLINIRDV--NDNAPRF 257 V++ DGGS + + +LI++ N NAP F Sbjct: 63 VVKVTDGGSLALESRAIVLIDVTPTTENRNAPVF 96 Score = 52.8 bits (121), Expect = 4e-06 Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 8/98 (8%) Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 TPV T+ A+D D + RL Y I G G F I + G I+VA L +KQ Y + Sbjct: 6 TPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GAISVAGRLSYKQRNNYSVV 63 Query: 441 VSATDSGGRS--DTAMVQINITDA--NNYAPVFENAPY 474 V TD G + A+V I++T N APVF + Y Sbjct: 64 VKVTDGGSLALESRAIVLIDVTPTTENRNAPVFASVQY 101 Score = 44.4 bits (100), Expect = 0.001 Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 9/107 (8%) Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A I T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ L Sbjct: 2 AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISVAGRLSY 54 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV--NDNEPVFKQQLY 586 + + Y + V DGG +L V I V N N PVF Y Sbjct: 55 KQRNNYSVVVKVTDGGSLALESRAIVLIDVTPTTENRNAPVFASVQY 101 Score = 42.7 bits (96), Expect = 0.004 Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 5/99 (5%) Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVAT 652 A + T V+ V A+D D+G NGR+ Y ++ G F I D +SG I L + Sbjct: 2 AAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISVAGRLSYKQRNN 59 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDI--NDSPPVFES 689 + + DGG+ S IV I + N + PVF S Sbjct: 60 YSVVVKVTDGGSLALESRAIVLIDVTPTTENRNAPVFAS 98 Score = 32.7 bits (71), Expect = 4.4 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 + V A D D G N L Y++ + G+ + D SG + +G+L + + Y ++ Sbjct: 8 VATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISVAGRLSYKQRNNYSVV 63 Query: 336 VTATDGG 342 V TDGG Sbjct: 64 VKVTDGG 70 >SB_12265| Best HMM Match : Cadherin (HMM E-Value=1.3e-10) Length = 110 Score = 56.8 bits (131), Expect = 2e-07 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRL 225 D PV A + A+D D+GAN + Y+I G F I DS SG +SL L Y Q +Y + Sbjct: 5 DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIV 62 Query: 226 VIRAQDGGSPSRSNTTQLLINI 247 V+ DGGSP+ + ++I++ Sbjct: 63 VVNVTDGGSPALKSRAMVVIDV 84 Score = 48.0 bits (109), Expect = 1e-04 Identities = 36/102 (35%), Positives = 49/102 (48%), Gaps = 12/102 (11%) Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 TPV T+ A+D D + RL Y I G G F I + G I++A L + Q Y++ Sbjct: 6 TPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GAISLAGMLSYNQRNNYIVV 63 Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480 V+ TD G + AMV I++T P N Y SV E Sbjct: 64 VNVTDGGSPALKSRAMVVIDVT------PKPRNLTYDVSVLE 99 Score = 46.0 bits (104), Expect = 4e-04 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 7/90 (7%) Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A I T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ +L Sbjct: 2 AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSY 54 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 + Y++ V DGG P+L V I V Sbjct: 55 NQRNNYIVVVNVTDGGSPALKSRAMVVIDV 84 Score = 39.9 bits (89), Expect = 0.029 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 3/85 (3%) Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVAT 652 A + T V+ V A+D D+G NGR+ Y ++ G F I D +SG I L Sbjct: 2 AAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQRNN 59 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKI 677 + + DGG+P S +V I + Sbjct: 60 YIVVVNVTDGGSPALKSRAMVVIDV 84 Score = 33.9 bits (74), Expect = 1.9 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 + V A D D G N L Y++ + G+ + D SG + +G L + Y ++ Sbjct: 8 VATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQRNNYIVV 63 Query: 336 VTATDGGDPPRSATA 350 V TDGG P + A Sbjct: 64 VNVTDGGSPALKSRA 78 >SB_49765| Best HMM Match : EGF (HMM E-Value=0) Length = 508 Score = 56.4 bits (130), Expect = 3e-07 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 19/179 (10%) Query: 1506 NVRDGCQSRADCMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQCVSACELGPCGAARCV 1563 ++R+ +R C+ S C S C + D TCTC G G C + L PC ++ C Sbjct: 110 DIREDTVTRP-CVSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHCDTVIPLKPCDSSPCS 168 Query: 1564 PD------QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWG-GSACGPCACDVTRGYH 1616 Q K Y+C C PGYT C + C GS C + Y Sbjct: 169 NGGVCNNTQDGKNYTCTCSPGYT--GRHCDTVIPKPCDSSPCNNGSVCNNTQDG--KNYT 224 Query: 1617 PHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 C+ HC + P+ C+ C N++ + C C PG GR CD Sbjct: 225 CTCSPGYTGRHC--DTVIPKA---CVSSPCSNGSICNNTQDGKNYTCTCSPGYTGRHCD 278 Score = 40.7 bits (91), Expect = 0.016 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 7/103 (6%) Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061 C P C TV+ S+ + ++TC C G+TG +C+T++ K Sbjct: 142 CTCSPGYTGRHCDTVIPLKPCDSSPCSNGGVCNNTQDGKNYTCTCSPGYTGRHCDTVIPK 201 Query: 1062 ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 C D S C +GS C ++G C+ YT C+ Sbjct: 202 -PC----DSSPCNNGSVCNNTQDGKNYT--CTCSPGYTGRHCD 237 Score = 40.7 bits (91), Expect = 0.016 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 C S+PC NG+ C++ D Y C C G+TG+ C Sbjct: 203 CDSSPCNNGSVCNNTQDGKNYTCTCSPGYTGRHC 236 Score = 40.7 bits (91), Expect = 0.016 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 C S+PC NG+ C++ D Y C C G+TG+ C Sbjct: 310 CDSSPCSNGSVCNNTQDGKNYTCSCSYGYTGRHC 343 Score = 40.3 bits (90), Expect = 0.022 Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 C S+PC NG C++ D Y C C G+TG+ C Sbjct: 162 CDSSPCSNGGVCNNTQDGKNYTCTCSPGYTGRHC 195 Score = 39.9 bits (89), Expect = 0.029 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 C S+PC NG+ C++ D Y C C G+TG+ C Sbjct: 120 CVSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHC 153 Score = 39.5 bits (88), Expect = 0.038 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 C S+PC NG+ C++ D Y C C G+TG+ C Sbjct: 244 CVSSPCSNGSICNNTQDGKNYTCTCSPGYTGRHC 277 Score = 39.1 bits (87), Expect = 0.050 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 6/64 (9%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 ++TC C G+TG +C+T++ C D S C +G C ++G C+ YT Sbjct: 139 NYTCTCSPGYTGRHCDTVIPLKPC----DSSPCSNGGVCNNTQDGKNYT--CTCSPGYTG 192 Query: 1101 AVCE 1104 C+ Sbjct: 193 RHCD 196 Score = 39.1 bits (87), Expect = 0.050 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 8/103 (7%) Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061 C P C TV+ S N+ SV ++TC C G+TG +C+T++ K Sbjct: 184 CTCSPGYTGRHCDTVIPKPCDSSPCNNGSVC-NNTQDGKNYTCTCSPGYTGRHCDTVIPK 242 Query: 1062 ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 A S C +GS C ++G C+ YT C+ Sbjct: 243 ACV-----SSPCSNGSICNNTQDGKNYT--CTCSPGYTGRHCD 278 Score = 39.1 bits (87), Expect = 0.050 Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 6/50 (12%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG-GILC 1089 ++TC C G+TG +C T L K SCE +C+ G C+ +G G +C Sbjct: 329 NYTCSCSYGYTGRHCNT-LKKLSCE----DIVCQYGGTCITINDGIGCVC 373 Score = 31.9 bits (69), Expect = 7.6 Identities = 28/90 (31%), Positives = 34/90 (37%), Gaps = 13/90 (14%) Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGC 1697 T C+ C N++ + C C PG GR CD V P C D Sbjct: 117 TRPCVSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHCDT-------VIPLKPC----DSS 165 Query: 1698 PRSFAGGVWWPRTKFGVETITDCPPGSSGR 1727 P S GGV T+ G C PG +GR Sbjct: 166 PCS-NGGV-CNNTQDGKNYTCTCSPGYTGR 193 >SB_40116| Best HMM Match : EGF (HMM E-Value=0) Length = 340 Score = 56.4 bits (130), Expect = 3e-07 Identities = 52/169 (30%), Positives = 67/169 (39%), Gaps = 30/169 (17%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC + C CV D TC C G G C V+ C+ PC A CV +Q G+ Sbjct: 4 DCHPNPCQYGGTCVDGLDDFTCLCVPGTTGKICHINVNYCDSEPCMNNATCVDEQ--DGF 61 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC-NKENG-KCHCK 1629 +C C PGYT T C + +EC A PC G C N ENG +C C Sbjct: 62 TCICAPGYTGPT--C-DGDIDEC--------AFNPC----LNG--AECINLENGFECVCL 104 Query: 1630 ENHYKPE---GTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 + +C P C G + +C C PG +G C+ Sbjct: 105 PGYTGKRCGIDIDDCTPSPCINGG--RCIDQVNDYECQCLPGFVGDNCE 151 Score = 46.4 bits (105), Expect = 3e-04 Identities = 46/184 (25%), Positives = 68/184 (36%), Gaps = 25/184 (13%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C ++C+ + C C G G +C + C PC RC+ DQ Y Sbjct: 80 ECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGGRCI-DQV-NDY 137 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGP------CACDVTRGY------HPH 1618 C C PG+ C E+ ++C G+ C C C + GY H Sbjct: 138 ECQCLPGFV--GDNC-ETNVDDCADNPCLNGATCIDGVNDYYCVCAI--GYYSKNCEHIS 192 Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678 CN+ + + + E T+ C C C G+ S C C G G C+ Sbjct: 193 CNRFSVVVLLICDLFLSE-TSTCTDCTCENGGTCGVSSVYGHWFCVCPKGFKGERCEIAD 251 Query: 1679 NAYA 1682 N A Sbjct: 252 NGCA 255 Score = 42.7 bits (96), Expect = 0.004 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C C+ PC NGAEC +L + + C C G+TGK C D T P GG Sbjct: 74 CDGDIDECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGG 128 Score = 40.7 bits (91), Expect = 0.016 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348 C + C++ PC NG C D Y C C+EG TGK+C Sbjct: 247 CEIADNGCATKPCQNGGSCCQDPVKGYSCICREGFTGKNC 286 Score = 39.9 bits (89), Expect = 0.029 Identities = 15/32 (46%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S PC N A C D D + C C G+TG C Sbjct: 43 CDSEPCMNNATCVDEQDGFTCICAPGYTGPTC 74 Score = 39.5 bits (88), Expect = 0.038 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343 CI D D++ L +V DN C C+ PC NGA C D + Y C C G+ Sbjct: 130 CI-DQVNDYECQCLPGFVGDN-----CETNVDDCADNPCLNGATCIDGVNDYYCVCAIGY 183 Query: 1344 TGKDC 1348 K+C Sbjct: 184 YSKNC 188 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/32 (40%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ +PC NG C D + Y C C G G +C Sbjct: 119 CTPSPCINGGRCIDQVNDYECQCLPGFVGDNC 150 Score = 35.9 bits (79), Expect = 0.47 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 5/48 (10%) Query: 1537 CTCEAGRVGPQCVSA---CELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 C C G G +C A C PC C D KGYSC C G+T Sbjct: 236 CVCPKGFKGERCEIADNGCATKPCQNGGSCCQDPV-KGYSCICREGFT 282 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/32 (43%), Positives = 15/32 (46%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C PC G C D D + C C G TGK C Sbjct: 5 CHPNPCQYGGTCVDGLDDFTCLCVPGTTGKIC 36 Score = 33.5 bits (73), Expect = 2.5 Identities = 12/19 (63%), Positives = 14/19 (73%) Query: 1038 PVTSFTCQCPEGFTGVNCE 1056 PV ++C C EGFTG NCE Sbjct: 269 PVKGYSCICREGFTGKNCE 287 Score = 32.7 bits (71), Expect = 4.4 Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 R I V + CQC GF G NCET + + +G+ C G Sbjct: 129 RCIDQVNDYECQCLPGFVGDNCETNVDDCADNPCLNGATCIDG 171 >SB_471| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 587 Score = 56.4 bits (130), Expect = 3e-07 Identities = 34/108 (31%), Positives = 43/108 (39%), Gaps = 11/108 (10%) Query: 1606 PCACDVTRGYHPHCNKENGKCHCKENHYKPE---------GTAECLPCQCYAAGSENSSC 1656 PC CD C+K G+C C+ N + G C C+C GS + C Sbjct: 340 PCECDPKGALDASCSKFGGQCTCRRNVVGRKCDRCMASYTGFPNCRKCECSPVGSVSPDC 399 Query: 1657 EAATGQCHCRPGVIGRACDACANAYAEVTPN-SGCEVVYDGCPRSFAG 1703 + TG C C G GR CD CA+ PN C G +F G Sbjct: 400 D-VTGHCTCTRGFGGRKCDRCASYGYYGYPNCKACNCDTRGSLSTFCG 446 Score = 52.4 bits (120), Expect = 5e-06 Identities = 52/195 (26%), Positives = 69/195 (35%), Gaps = 32/195 (16%) Query: 1516 DCMLSICPPYSKCVTSWD-SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQ--TPKGYS 1572 +C C P D + CTC G G +C G G C T S Sbjct: 383 NCRKCECSPVGSVSPDCDVTGHCTCTRGFGGRKCDRCASYGYYGYPNCKACNCDTRGSLS 442 Query: 1573 CACEPGYTLTTSGCIESGK-EECPGGWWGGSACGPCACD-----VTRGYHPHCNKENG-K 1625 C E K ++C G++ C C C+ + G C N K Sbjct: 443 TFCGSWGQCQCRMNFEGLKCDQCRVGYYDFPRCKQCGCNPAGIRLLPGQQNTCGNGNDTK 502 Query: 1626 CHCKEN------------HY-----KPEGTAECLPCQCYAAGSENS--SCEAATGQCHCR 1666 C CKEN H+ P+G C PC C G+ S C+ G+C+C+ Sbjct: 503 CTCKENVQGAECEQCKSMHFGLSIFNPKG---CRPCGCNLNGTLGSIGDCDKDHGRCNCK 559 Query: 1667 PGVIGRACDACANAY 1681 V GR C CA+ Y Sbjct: 560 AHVTGRECGRCADGY 574 Score = 46.0 bits (104), Expect = 4e-04 Identities = 34/127 (26%), Positives = 42/127 (33%), Gaps = 15/127 (11%) Query: 1568 PKGY---SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG 1624 PKG SC+ G + + C + G C C C P C+ G Sbjct: 345 PKGALDASCSKFGGQCTCRRNVVGRKCDRCMASYTGFPNCRKCECSPVGSVSPDCDV-TG 403 Query: 1625 KCHCKENH----------YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C C Y G C C C GS ++ C + GQC CR G C Sbjct: 404 HCTCTRGFGGRKCDRCASYGYYGYPNCKACNCDTRGSLSTFC-GSWGQCQCRMNFEGLKC 462 Query: 1675 DACANAY 1681 D C Y Sbjct: 463 DQCRVGY 469 Score = 40.7 bits (91), Expect = 0.016 Identities = 31/128 (24%), Positives = 51/128 (39%), Gaps = 12/128 (9%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG----PQCVSACELGPCGAARCVPDQ 1566 C +R + + C + +C + C+ RVG P+C C P G R +P Q Sbjct: 435 CDTRGS-LSTFCGSWGQCQCRMNFEGLKCDQCRVGYYDFPRC-KQCGCNPAGI-RLLPGQ 491 Query: 1567 TP---KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV--TRGYHPHCNK 1621 G C + + C + + C PC C++ T G C+K Sbjct: 492 QNTCGNGNDTKCTCKENVQGAECEQCKSMHFGLSIFNPKGCRPCGCNLNGTLGSIGDCDK 551 Query: 1622 ENGKCHCK 1629 ++G+C+CK Sbjct: 552 DHGRCNCK 559 >SB_43550| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 1182 Score = 56.0 bits (129), Expect = 4e-07 Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 21/187 (11%) Query: 1575 CEP--GYTLTTSGCIESGKEECPGGWWGGS--ACGPCACDVTRGYHPHCNKENGKCHCKE 1630 C+P G S I + C G +G S C C CD CN G+C C+ Sbjct: 248 CDPIGGQCKCKSNVIGQRCDRCAPGSFGFSNKGCSACDCDRIGAIDNFCNILTGQCQCRN 307 Query: 1631 -------NHYKPE--GTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRACDACA-N 1679 + P G C PC+CY SSC TG C C+ +G+ C+ACA Sbjct: 308 WASGRQCSLCPPNMWGFPLCRPCRCY---GHASSCNPKTGVCVDCQHNTVGKNCEACAVG 364 Query: 1680 AYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITD---CPPGSSGRATRTCDETK 1736 Y T + + CP +G + T C G R C+E Sbjct: 365 FYGIATKGTPNDCKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDKCQVGYTGRQCEECA 424 Query: 1737 DVPWQDP 1743 D + +P Sbjct: 425 DGYYGNP 431 Score = 54.4 bits (125), Expect = 1e-06 Identities = 46/170 (27%), Positives = 64/170 (37%), Gaps = 20/170 (11%) Query: 1539 CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIE-----SGKEE 1593 C+ G G QC C G G VP + K SC T++ GC + G Sbjct: 411 CQVGYTGRQC-EECADGYYGNP-LVPGGSCKPCSCNNNIDPTVSGKGCQQCDCCIEGSLR 468 Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK-----------ENHYKPEGTAECL 1642 G C C C + C++ G+C CK E+++ C Sbjct: 469 SMCNQVSGKGCQQCDCCIEGSLRSMCSQITGQCQCKAGFGGPRCCECEDNFWGSPPDGCS 528 Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692 C AGS + C+ TG+C C+ G IG D CA + P CE+ Sbjct: 529 ACNGNPAGSGHLQCDRDTGKCLCKVGHIGDKWDMCAADTSGKMPQ--CEI 576 Score = 53.6 bits (123), Expect = 2e-06 Identities = 47/170 (27%), Positives = 63/170 (37%), Gaps = 30/170 (17%) Query: 1533 DSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSC-ACEPGYTLTTSGCIESGK 1591 D C C G G + +C + TP C C+ GYT C Sbjct: 376 DCKRCQCPGGSSGNKFSESCYVDT--------STTPPSVLCDKCQVGYT--GRQC----- 420 Query: 1592 EECPGGWWG-----GSACGPCACDVTRGYHPHCN-KENGKCHC-----KENHYKPEGTAE 1640 EEC G++G G +C PC+C+ P + K +C C + Sbjct: 421 EECADGYYGNPLVPGGSCKPCSCN--NNIDPTVSGKGCQQCDCCIEGSLRSMCNQVSGKG 478 Query: 1641 CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 C C C GS S C TGQC C+ G G C C + + +P GC Sbjct: 479 CQQCDCCIEGSLRSMCSQITGQCQCKAGFGGPRCCECEDNFWG-SPPDGC 527 Score = 37.9 bits (84), Expect = 0.12 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 6/65 (9%) Query: 1631 NHYKPEGTAECLPCQCYAAGSENSS-----CEAATGQCHCRPGVIGRACDACANAYAEVT 1685 N K +G C C G++ + C+ GQC C+ VIG+ CD CA + Sbjct: 218 NKNKYDGGNNDDTCNCDPKGTQRDANGTLVCDPIGGQCKCKSNVIGQRCDRCAPGSFGFS 277 Query: 1686 PNSGC 1690 N GC Sbjct: 278 -NKGC 281 >SB_9705| Best HMM Match : Cadherin (HMM E-Value=0.013) Length = 130 Score = 55.2 bits (127), Expect = 7e-07 Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 14/134 (10%) Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 L+ E+ A H+++ D G+PP+S +I + ++ND P Y+ EN+PI + Sbjct: 8 LNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDKPRGLLLS--NQYVKENAPINS 65 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 IG+ A D D G V +S+ DD+ F ++ LV DYE+ K ++ Sbjct: 66 VIGQFSARDEDNGQRLV--FSL-DNDDNGRFRVD-----GLGRLVKAKQTDYET-SKAHQ 116 Query: 765 LVIRA---ASPPLW 775 + +R +P LW Sbjct: 117 ITVRVTDDGNPRLW 130 Score = 52.4 bits (120), Expect = 5e-06 Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 10/130 (7%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 L+YE + + +R D GSP +S I + +VND PR L + V EN PI Sbjct: 8 LNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDK-PRGLL-LSNQYVKENAPINS 65 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 I + A D D G L +++ D D G +D G + + Q D ET +Q+ Sbjct: 66 VIGQFSARDEDNG--QRLVFSL-DNDDNGR----FRVD-GLGRLVKAKQTDYETSKAHQI 117 Query: 335 LVTATDGGDP 344 V TD G+P Sbjct: 118 TVRVTDDGNP 127 Score = 42.7 bits (96), Expect = 0.004 Identities = 31/126 (24%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX-XXXFMPGQYEVELAEDEPP 381 +L+ E A + + V TD G PP+S + QY + E+ P Sbjct: 7 KLNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDKPRGLLLSNQY---VKENAPI 63 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 + + +A D D RL + + + GRF + +G G + A+ D++ + + +TV Sbjct: 64 NSVIGQFSARDEDNGQRLVFSL-DNDDNGRFRV---DGLGRLVKAKQTDYETSKAHQITV 119 Query: 442 SATDSG 447 TD G Sbjct: 120 RVTDDG 125 Score = 39.1 bits (87), Expect = 0.050 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 7/127 (5%) Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 L+ E + + + V D G P S + I+V +VND L + E+A + + Sbjct: 8 LNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDKPRGL--LLSNQYVKENAPINS 65 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 + Q A D D G R+ + LD D G F +D +++ K D E+ H + Sbjct: 66 VIGQFSARDEDNG--QRLVFSLDNDD--NGRFRVDGLGRLVKA-KQTDYETSKAHQITVR 120 Query: 659 AIDGGTP 665 D G P Sbjct: 121 VTDDGNP 127 Score = 38.7 bits (86), Expect = 0.066 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 11/131 (8%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 L+ E A + + V+ TD SP I VN ++D S + V E+ Sbjct: 8 LNYENNAYHNIRVRTTDSGSPPKS-FERNFNITVNNVNDKPRGLLLSNQY----VKENAP 62 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 + N VI + A D D G + + +F +D L G + K DYE ++++ Sbjct: 63 I--NSVIGQFSARDEDNGQRLVFS---LDNDDNGRFRVDGL-GRLVKAKQTDYETSKAHQ 116 Query: 225 LVIRAQDGGSP 235 + +R D G+P Sbjct: 117 ITVRVTDDGNP 127 >SB_32282| Best HMM Match : Laminin_G_2 (HMM E-Value=0) Length = 897 Score = 54.8 bits (126), Expect = 9e-07 Identities = 45/134 (33%), Positives = 65/134 (48%), Gaps = 12/134 (8%) Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHR--IHLKLKFATQTTSGLLLYNGRYNE 1150 SI+AA A + R F +S+++ P L R R L + F + GLLLY GR ++ Sbjct: 302 SIEAAEPNARSARQPR-FKGTSYMSLPRLPRSARTSFELSIMFKASSGDGLLLYGGRKDK 360 Query: 1151 RHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITM 1210 R DFLAL L R G + F FS G +++ N+ WH V + R + Sbjct: 361 RKDFLALGL------RNG--HVEFRFSCGADIAQVRSRQNITLNQWHNVVVFRDKRDAHL 412 Query: 1211 ILDDCDKVL-SLAG 1223 ++D+ D V SL G Sbjct: 413 MVDNGDLVTQSLKG 426 Score = 50.8 bits (116), Expect = 2e-05 Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 33/212 (15%) Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDC--ADSTGPPWRFGGDGMLSFNPLLRPIQLPWLN 1379 C+NG C D Y C C G+TG C A P F GDG + F +L N Sbjct: 689 CFNGGTCQAKMDHYKCHCAVGYTGMMCERARRVSAP-TFAGDGFMKFKGSEILSRLSGKN 747 Query: 1380 A---LSIRTRQRDAFVMSIQLKS-------------GLLHYSYN----GETMYLPMATLS 1419 RT++ ++S+Q +S G+L Y+ ET+ ATL Sbjct: 748 TELEFLFRTQESSGLLLSVQKESVSHGDHITIGLIDGILEVRYDLGVGRETVIRSTATLD 807 Query: 1420 DGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGK--ILIGGLDTTAGLLAS 1477 DG WH ++ + VD ++ +A+ Q + + + IGG T S Sbjct: 808 DGYWHSVKFVRKSLAAYLKVDDEIKA----GIASDSQYRQLNSDVLFIGGAPTVDRRFMS 863 Query: 1478 DVGFFEGCIQDVRIGTAQ-SLLNRPTVRENVR 1508 + GC++D+ +G L + T +NVR Sbjct: 864 GL---VGCLKDLIVGDVPVDLASEVTSGQNVR 892 Score = 37.9 bits (84), Expect = 0.12 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 11/100 (11%) Query: 1256 LDLTGPLQIGGLPN---IPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVAD---NGTLAG 1309 +DL L +GG+P + S + F GC+ F +D + +DL+ + D + + Sbjct: 431 MDLKTRLFLGGVPRMRRVTSDAVPYHSGFTGCVKSFVVDGRMLDLSQALGDVVKSRQVEE 490 Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDC 1348 C E R C C++ A C + IC C G G+ C Sbjct: 491 CGESRD-CE---CHHNAPCHYAVSGEPICACPLGTYGRLC 526 Score = 32.7 bits (71), Expect = 4.4 Identities = 14/44 (31%), Positives = 23/44 (52%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 + C C G+TG+ CE ++ GDG + GS+ ++R G Sbjct: 702 YKCHCAVGYTGMMCERARRVSAPTFAGDGFMKFKGSEILSRLSG 745 >SB_22642| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1574 Score = 54.4 bits (125), Expect = 1e-06 Identities = 40/145 (27%), Positives = 54/145 (37%), Gaps = 27/145 (18%) Query: 1557 CGAARCVPDQTPKGYSCAC--EPGYTLTTSGCIESGK------EECPGGWWG-----GSA 1603 C A C P G C +P L CI + C G++ Sbjct: 1406 CIACNCDPTGGVNGGECEAKNDPAAGLVAGRCICKRNVGGVRCDRCKAGFFNLTTDNPDG 1465 Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKE------------NHYKPEGT-AECLPCQCYAAG 1650 C C C+ G CN + G+C CK ++ T A C C C G Sbjct: 1466 CKACGCNPL-GTIGECNPDTGRCTCKRYVEGEDCDRCASEYWGLSSTPAGCSNCACDVGG 1524 Query: 1651 SENSSCEAATGQCHCRPGVIGRACD 1675 S ++ C+ TGQC CR G+ GR C+ Sbjct: 1525 SYDNQCDKQTGQCRCRKGITGRQCE 1549 Score = 41.5 bits (93), Expect = 0.009 Identities = 40/154 (25%), Positives = 56/154 (36%), Gaps = 16/154 (10%) Query: 1539 CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGW 1598 CE VG C L ++ D +C C+P +G + G+ E Sbjct: 1376 CEHNTVGRNCERCKPLHYQDPSKKFSDPDAC-IACNCDP------TGGVNGGECEAKNDP 1428 Query: 1599 WGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEA 1658 G G C C G C++ C + + C C C G+ C Sbjct: 1429 AAGLVAGRCICKRNVG-GVRCDR----CKAGFFNLTTDNPDGCKACGCNPLGTIGE-CNP 1482 Query: 1659 ATGQCHCRPGVIGRACDACANAY--AEVTPNSGC 1690 TG+C C+ V G CD CA+ Y TP +GC Sbjct: 1483 DTGRCTCKRYVEGEDCDRCASEYWGLSSTP-AGC 1515 >SB_2045| Best HMM Match : EGF (HMM E-Value=0) Length = 1101 Score = 54.0 bits (124), Expect = 2e-06 Identities = 47/176 (26%), Positives = 62/176 (35%), Gaps = 20/176 (11%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPG 1578 C P+ CV + TCTC G G +C + C+ PC Y C C G Sbjct: 843 CGPHGTCVDGVNRYTCTCHPGWNGTKCDIDIDECDPNPCLRGGQCHQTNNASYICTCPVG 902 Query: 1579 YTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638 Y T C E+ EC ++ C D GY C +C N + Sbjct: 903 Y--TGQKC-ETEINECLSSSVKCTSGSTC-LDRLDGYECQCPPGLKGIYCSSN------S 952 Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC----DACANAYAEVTPNSGC 1690 + C P C S N + C C PG GR C D C ++ N+ C Sbjct: 953 SWCEPNPCI---SGNCTDTGTNFTCLCNPGFTGRYCEIDIDECVSSPCGNVSNTKC 1005 Score = 47.6 bits (108), Expect = 1e-04 Identities = 19/39 (48%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C PC NGA C DL Y C C G TGKDC Sbjct: 586 CTTTTDECDPNPCKNGASCKDLHLDYNCSCPVGFTGKDC 624 Score = 45.6 bits (103), Expect = 6e-04 Identities = 62/247 (25%), Positives = 80/247 (32%), Gaps = 39/247 (15%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC------------VSACELGPC 1557 C++ D C C C + TCTC G G QC ++ C GPC Sbjct: 463 CETEIDLCEPEPCANGGSCTNFYTYYTCTCVPGYTGKQCAAGYTGTNCETNINECASGPC 522 Query: 1558 -GAARCVPDQTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRG 1614 CV + GY C C G+T + E C G CD G Sbjct: 523 RNNGTCVDE--VNGYQCLCLQGFTGQRCETDIDECLTTPCLNGGTCHDEINNFRCDCPTG 580 Query: 1615 YH-PHCNKENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCE-----AATGQC-- 1663 Y+ C +C CK N + C C G CE G C Sbjct: 581 YYGKTCTTTTDECDPNPCK-NGASCKDLHLDYNCSC-PVGFTGKDCEINIDDCTVGSCAG 638 Query: 1664 --HCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETIT-DC 1720 C+ G+ +C C Y + C+ D C S K GV T +C Sbjct: 639 TGTCKDGINDFSC-VCNTGYT----GAKCDSNIDDCAASGQPCQNGATCKDGVNQYTCEC 693 Query: 1721 PPGSSGR 1727 P G +GR Sbjct: 694 PLGFTGR 700 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C + C PC NG C++ + Y C C G+TGK CA Sbjct: 463 CETEIDLCEPEPCANGGSCTNFYTYYTCTCVPGYTGKQCA 502 Score = 43.6 bits (98), Expect = 0.002 Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C C + PC NG C D + + CDC G+ GK C +T Sbjct: 548 CETDIDECLTTPCLNGGTCHDEINNFRCDCPTGYYGKTCTTTT 590 Score = 43.2 bits (97), Expect = 0.003 Identities = 42/170 (24%), Positives = 57/170 (33%), Gaps = 17/170 (10%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCG-AARCVPDQTPKGY 1571 DC + C + CV + TC C G G C ++ C PC CV + Y Sbjct: 708 DCASAACANGATCVDGIANYTCNCSIGYKGRHCGERINYCVTNPCKYQGTCVNEL--GYY 765 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP---CACDVTRGYH-PHCNKENGKCH 1627 C C+ GY T C G A P C+ GY +C + C Sbjct: 766 RCLCKEGYNGTNCEIDPCKWNPCQRN--GTCAVVPNTLYRCECKEGYSGRNCEIDIDDCD 823 Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIGRACD 1675 N + E + Y + +C + C C PG G CD Sbjct: 824 PNNNIWNEENSNN---VGAYGFCGPHGTCVDGVNRYTCTCHPGWNGTKCD 870 Score = 41.5 bits (93), Expect = 0.009 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Query: 1299 SYVADNG-TLAGCPEKRSRCSSA--PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 S V + G T A C C+++ PC NGA C D + Y C+C G TG+ C Sbjct: 650 SCVCNTGYTGAKCDSNIDDCAASGQPCQNGATCKDGVNQYTCECPLGFTGRHC 702 Score = 40.3 bits (90), Expect = 0.022 Identities = 15/34 (44%), Positives = 20/34 (58%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C+SA C NGA C D Y C+C G+ G+ C + Sbjct: 709 CASAACANGATCVDGIANYTCNCSIGYKGRHCGE 742 Score = 39.1 bits (87), Expect = 0.050 Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T C + C+S PC N C D + Y C C +G TG+ C Sbjct: 506 TGTNCETNINECASGPCRNNGTCVDEVNGYQCLCLQGFTGQRC 548 Score = 38.3 bits (85), Expect = 0.088 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348 C + ++C +PC N C + D Y C CK +TGK+C Sbjct: 424 CDQDLNKCRYSPCQNEGTCLNTGPDAYSCACKYKYTGKNC 463 Score = 37.5 bits (83), Expect = 0.15 Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 8/58 (13%) Query: 1528 CVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAA---RCVPDQTPKGYSCACEPGY 1579 C + + TC C G G C + C PCG +C+ P YSC C P Y Sbjct: 965 CTDTGTNFTCLCNPGFTGRYCEIDIDECVSSPCGNVSNTKCI--DLPGNYSCRCPPDY 1020 Score = 37.1 bits (82), Expect = 0.20 Identities = 14/38 (36%), Positives = 21/38 (55%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 V +TC+CP GFTG +CE + + +G+ C G Sbjct: 686 VNQYTCECPLGFTGRHCEINIDDCASAACANGATCVDG 723 Score = 37.1 bits (82), Expect = 0.20 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 4/45 (8%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 S+ C CP G+TG CET + E C SGS C+ R +G Sbjct: 894 SYICTCPVGYTGQKCETEIN----ECLSSSVKCTSGSTCLDRLDG 934 Score = 35.9 bits (79), Expect = 0.47 Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 3/46 (6%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348 NGT C C PC G +C + +YIC C G+TG+ C Sbjct: 865 NGTK--CDIDIDECDPNPCLRGGQCHQTNNASYICTCPVGYTGQKC 908 Score = 35.5 bits (78), Expect = 0.62 Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 1/33 (3%) Query: 1317 CSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348 C PC C+ + +T Y C+CKEG++G++C Sbjct: 783 CKWNPCQRNGTCAVVPNTLYRCECKEGYSGRNC 815 Score = 34.7 bits (76), Expect = 1.1 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 10/76 (13%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + +F C CP G+ G C T T C D + C++G+ C L CS + Sbjct: 570 INNFRCDCPTGYYGKTCTT--TTDEC----DPNPCKNGASCKDLH----LDYNCSCPVGF 619 Query: 1099 TTAVCELRARSFPVSS 1114 T CE+ V S Sbjct: 620 TGKDCEINIDDCTVGS 635 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/39 (35%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E+ + C + PC C + Y C CKEG+ G +C Sbjct: 740 CGERINYCVTNPCKYQGTCVNELGYYRCLCKEGYNGTNC 778 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S C PC +G C+D + C C G TG+ C Sbjct: 948 CSSNSSWCEPNPCISG-NCTDTGTNFTCLCNPGFTGRYC 985 Score = 34.3 bits (75), Expect = 1.4 Identities = 39/150 (26%), Positives = 52/150 (34%), Gaps = 24/150 (16%) Query: 1537 CTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593 C C+ G C ++ C PC + P YSCAC+ Y T C E+ + Sbjct: 413 CVCKPDWQGDNCDQDLNKCRYSPCQNEGTCLNTGPDAYSCACK--YKYTGKNC-ETEIDL 469 Query: 1594 C-PGGWWGGSACGP----CACDVTRGY-HPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647 C P G +C C GY C +C+ N EC C Sbjct: 470 CEPEPCANGGSCTNFYTYYTCTCVPGYTGKQCAAGYTGTNCETN------INECASGPC- 522 Query: 1648 AAGSENSSC--EAATGQCHCRPGVIGRACD 1675 N +C E QC C G G+ C+ Sbjct: 523 ---RNNGTCVDEVNGYQCLCLQGFTGQRCE 549 Score = 33.1 bits (72), Expect = 3.3 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGD---GSICRSGSQCVARREG 1085 T +TC C G+TG C T +CE + + CR+ CV G Sbjct: 486 TYYTCTCVPGYTGKQCAAGYTGTNCETNINECASGPCRNNGTCVDEVNG 534 Score = 33.1 bits (72), Expect = 3.3 Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 8/67 (11%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + F+C C G+TG C++ + + G C++G+ C + G+ C + Sbjct: 646 INDFSCVCNTGYTGAKCDSNIDDCA----ASGQPCQNGATC----KDGVNQYTCECPLGF 697 Query: 1099 TTAVCEL 1105 T CE+ Sbjct: 698 TGRHCEI 704 Score = 33.1 bits (72), Expect = 3.3 Identities = 11/23 (47%), Positives = 17/23 (73%) Query: 1041 SFTCQCPEGFTGVNCETILTKAS 1063 +++C+CP + G NCETI +AS Sbjct: 1011 NYSCRCPPDYEGANCETIKMEAS 1033 Score = 32.3 bits (70), Expect = 5.8 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 + C CP GFTG +CE + C V GS C C + GI C + YT A Sbjct: 611 YNCSCPVGFTGKDCE--INIDDCTV---GS-CAGTGTC----KDGINDFSCVCNTGYTGA 660 Query: 1102 VCE 1104 C+ Sbjct: 661 KCD 663 Score = 32.3 bits (70), Expect = 5.8 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 1310 CPEKRSRC--SSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C + + C SS C +G+ C D D Y C C G G C+ ++ Sbjct: 908 CETEINECLSSSVKCTSGSTCLDRLDGYECQCPPGLKGIYCSSNS 952 Score = 32.3 bits (70), Expect = 5.8 Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 9/80 (11%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 T+FTC C GFTG CE + + C G++ S ++C+ G C+ C D Y Sbjct: 970 TNFTCLCNPGFTGRYCEIDIDE--CVSSPCGNV--SNTKCI-DLPGNYSCR-CPPD--YE 1021 Query: 1100 TAVCELRARSFPVSSFLTFP 1119 A CE VS+ L FP Sbjct: 1022 GANCETIKMEASVSTVL-FP 1040 >SB_8580| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 426 Score = 53.6 bits (123), Expect = 2e-06 Identities = 41/119 (34%), Positives = 53/119 (44%), Gaps = 16/119 (13%) Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELGP--CGA-AR 1561 C +C L+I CP CV + S TC C+ G V C + C LG C A A Sbjct: 202 CDDIDECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASAD 261 Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIES-----GKEECPGGWWGGSACGPCACDVTRGY 1615 CV + Y+C C+PGYTL + CI++ G CP + G C RGY Sbjct: 262 CVNNNG--SYTCRCKPGYTLVNNTCIDTDECALGVATCPASADCVNNDGSYTCRCKRGY 318 Score = 47.2 bits (107), Expect = 2e-04 Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 13/100 (13%) Query: 1507 VRDGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQCVSA--CELG--PCG 1558 V + C+ +C L + CP + CV + S TC C+ G V C+ C LG C Sbjct: 239 VNNTCEDIDECALGVANCPASADCVNNNGSYTCRCKPGYTLVNNTCIDTDECALGVATCP 298 Query: 1559 A-ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597 A A CV + Y+C C+ GYTL C + +EC G Sbjct: 299 ASADCVNNDG--SYTCRCKRGYTLVNKTCKDI--DECALG 334 Score = 44.4 bits (100), Expect = 0.001 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 11/89 (12%) Query: 1507 VRDGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELG--PCG 1558 V + C +C L + CP + CV + S TC C+ G V C + C LG C Sbjct: 280 VNNTCIDTDECALGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCKDIDECALGVATCP 339 Query: 1559 A-ARCVPDQTPKGYSCACEPGYTLTTSGC 1586 A A CV + Y+C C+ G+TL + C Sbjct: 340 ASADCVNNNG--SYTCRCKRGFTLVNNTC 366 Score = 38.7 bits (86), Expect = 0.066 Identities = 37/156 (23%), Positives = 58/156 (37%), Gaps = 18/156 (11%) Query: 1549 VSACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606 V+ C P C + + T + C+C+PGYT S + + P Sbjct: 152 VNECTETPYVCSGENSICENTDGSFKCSCKPGYTPKFSKAV----GDAPANLTSCDDIDE 207 Query: 1607 CACDV-TRGYHPHCNKENGK--CHCKENHYKPEGTAECL-PCQCYAAGSENSS-CEAATG 1661 C ++ T + +C +G C CK + T E + C A S+ C G Sbjct: 208 CKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCVNNNG 267 Query: 1662 Q--CHCRPG--VIGRAC---DACANAYAEVTPNSGC 1690 C C+PG ++ C D CA A ++ C Sbjct: 268 SYTCRCKPGYTLVNNTCIDTDECALGVATCPASADC 303 >SB_54839| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1409 Score = 53.6 bits (123), Expect = 2e-06 Identities = 44/168 (26%), Positives = 61/168 (36%), Gaps = 12/168 (7%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C +CTC+AG G C V+ C PC ++ GYS Sbjct: 815 ECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSENPCKNGGVCKNE-HGGYS 873 Query: 1573 CACEPGY--TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 CAC+ G+ E K C G + G +C G+ N E C + Sbjct: 874 CACKAGFMGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACKAGFTGK-NCEQDVNECSK 932 Query: 1631 NHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 N K +G + C C AG +CE +C P G C Sbjct: 933 NPCKNDGVCKNEHGGYSCAC-KAGFTGKNCEQDMNECSKNPCQNGGVC 979 Score = 51.6 bits (118), Expect = 9e-06 Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 16/195 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C +CTC+AG G C V+ C PC ++ GYS Sbjct: 1043 ECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTCEQDVNECSKNPCKNGGVCKNE-HGGYS 1101 Query: 1573 CACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 CAC+ +T E K C G + G +C G+ +++ C + Sbjct: 1102 CACKAEFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVN-ECSK 1160 Query: 1631 NHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT- 1685 N K G + C C AG +CE +C P G C Y+ V Sbjct: 1161 NPCKNGGVCKNEHGGYSCTC-KAGFTGKNCEQDVNECSTNPCQNGGVCKNEHGGYSCVCK 1219 Query: 1686 ---PNSGCEVVYDGC 1697 CE D C Sbjct: 1220 AGFTGKNCEQDVDEC 1234 Score = 50.0 bits (114), Expect = 3e-05 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 16/143 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C +CTC+AG G C V+ C PC ++ GYS Sbjct: 1157 ECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSTNPCQNGGVCKNE-HGGYS 1215 Query: 1573 CACEPGYTLTTSGCIESGKEECPG--GWWGGSAC----GPCACDVTRGY-HPHCNKENGK 1625 C C+ G+ T C E +EC G G C G +C GY +C ++ + Sbjct: 1216 CVCKAGF--TGKNC-EQDVDECAGVNPCHHGGVCSNSHGGYSCKCASGYTGKNCEQDKNE 1272 Query: 1626 CHCKE--NHYKPEGTAECLPCQC 1646 C N+ K T C C Sbjct: 1273 CKVNPCLNNGKCINTPGSYKCNC 1295 Score = 49.2 bits (112), Expect = 5e-05 Identities = 46/186 (24%), Positives = 68/186 (36%), Gaps = 11/186 (5%) Query: 1498 LNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL 1554 LNRP V G C C C + +CTC++G G C V+ C Sbjct: 644 LNRPPVCHLRYCGNAEFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSK 703 Query: 1555 GPCGAARCVPDQTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVT 1612 PC ++ GYSCAC+ G+T E + C G + G +C Sbjct: 704 NPCKNGGVCKNEHG-GYSCACKAGFTGKNCEQDVNECSENPCKNGGVCKNEHGGYSCACK 762 Query: 1613 RGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAA----TGQCHCRPG 1668 G+ N E C +N + G A+ A ++S ++A +C+ P Sbjct: 763 AGFTGK-NCEQDVNECSKNPCQNGGVAKTNMADTLALAKQDSRAKSANKVHVNECNKNPC 821 Query: 1669 VIGRAC 1674 G C Sbjct: 822 QNGGVC 827 Score = 48.4 bits (110), Expect = 8e-05 Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 12/168 (7%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C +C C+AG G C ++ C PC ++ GYS Sbjct: 929 ECSKNPCKNDGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNKHG-GYS 987 Query: 1573 CACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 CAC+ G+T E K C G + G +C + N E C + Sbjct: 988 CACKAGFTGKNCEQDVNECSKYPCQNGGVCKNEHGGYSC-ACKAEFTGKNCEQDVNECSK 1046 Query: 1631 NHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 N K G + C C AG +CE +C P G C Sbjct: 1047 NPCKNGGVCKNEHGGYSCTC-KAGFTGKTCEQDVNECSKNPCKNGGVC 1093 Score = 46.4 bits (105), Expect = 3e-04 Identities = 17/32 (53%), Positives = 20/32 (62%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSS PC NG C ++ Y C CK G TGK+C Sbjct: 663 CSSKPCKNGGTCREVNGAYSCTCKSGFTGKNC 694 Score = 46.0 bits (104), Expect = 4e-04 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 961 CEQDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNC 999 Score = 45.6 bits (103), Expect = 6e-04 Identities = 18/46 (39%), Positives = 23/46 (50%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355 C + + CS PC NG C + Y C CK G TGK+C + P Sbjct: 313 CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQAPSKP 358 Score = 45.6 bits (103), Expect = 6e-04 Identities = 41/172 (23%), Positives = 61/172 (35%), Gaps = 12/172 (6%) Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568 Q +C + C C +C C+AG G C V+ C PC ++ Sbjct: 963 QDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSKYPCQNGGVCKNE-H 1021 Query: 1569 KGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 GYSCAC+ +T E K C G + G +C G+ +++ Sbjct: 1022 GGYSCACKAEFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTCEQDVN- 1080 Query: 1627 HCKENHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C +N K G + C C A + +CE +C P G C Sbjct: 1081 ECSKNPCKNGGVCKNEHGGYSCACKAEFT-GKNCEQDVNECSKNPCKNGGVC 1131 Score = 44.8 bits (101), Expect = 0.001 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C ++ C C +C C+AG G C V+ C + PC ++ GYS Sbjct: 464 ECSINPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNE-HGGYS 522 Query: 1573 CACEPGYT 1580 CAC+ G+T Sbjct: 523 CACKAGFT 530 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 885 CEQDVNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKNC 923 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 1151 CEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNC 1189 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/39 (43%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS+ PC NG C + Y C CK G TGK+C Sbjct: 1189 CEQDVNECSTNPCQNGGVCKNEHGGYSCVCKAGFTGKNC 1227 Score = 44.4 bits (100), Expect = 0.001 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 694 CEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNC 732 Score = 44.4 bits (100), Expect = 0.001 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 732 CEQDVNECSENPCKNGGVCKNEHGGYSCACKAGFTGKNC 770 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/39 (43%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK C Sbjct: 1037 CEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTC 1075 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 36 CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 74 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 496 CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 534 Score = 43.2 bits (97), Expect = 0.003 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C +C C+AG G C V+ C + PC ++ GYS Sbjct: 281 ECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNEHG-GYS 339 Query: 1573 CACEPGYT 1580 CAC+ G+T Sbjct: 340 CACKAGFT 347 Score = 43.2 bits (97), Expect = 0.003 Identities = 17/39 (43%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK C Sbjct: 1113 CEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKIC 1151 Score = 41.9 bits (94), Expect = 0.007 Identities = 16/34 (47%), Positives = 19/34 (55%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + CS PC NG C + Y C CK G TGK+C Sbjct: 280 NECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNC 313 Score = 41.9 bits (94), Expect = 0.007 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G GK+C Sbjct: 847 CEQDVNECSENPCKNGGVCKNEHGGYSCACKAGFMGKNC 885 Score = 41.5 bits (93), Expect = 0.009 Identities = 16/34 (47%), Positives = 19/34 (55%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + CS PC NG C + Y C CK G TGK+C Sbjct: 3 NECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNC 36 Score = 41.5 bits (93), Expect = 0.009 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C +C C+ G G C V+ C + PC ++ GYS Sbjct: 4 ECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHG-GYS 62 Query: 1573 CACEPGYT 1580 CAC+ G+T Sbjct: 63 CACKAGFT 70 Score = 41.5 bits (93), Expect = 0.009 Identities = 15/34 (44%), Positives = 19/34 (55%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C+ PC NG C + Y C CK G TGK+C Sbjct: 814 NECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNC 847 Score = 41.5 bits (93), Expect = 0.009 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC N C + Y C CK G TGK+C Sbjct: 923 CEQDVNECSKNPCKNDGVCKNEHGGYSCACKAGFTGKNC 961 Score = 41.5 bits (93), Expect = 0.009 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK TGK+C Sbjct: 999 CEQDVNECSKYPCQNGGVCKNEHGGYSCACKAEFTGKNC 1037 Score = 41.1 bits (92), Expect = 0.012 Identities = 16/34 (47%), Positives = 19/34 (55%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + CS PC NG C + Y C CK G TGK+C Sbjct: 463 NECSINPCKNGGVCKNEHGGYSCACKAGFTGKNC 496 Score = 41.1 bits (92), Expect = 0.012 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK TGK+C Sbjct: 1075 CEQDVNECSKNPCKNGGVCKNEHGGYSCACKAEFTGKNC 1113 Score = 40.3 bits (90), Expect = 0.022 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+ PC++G CS+ Y C C G+TGK+C Sbjct: 1227 CEQDVDECAGVNPCHHGGVCSNSHGGYSCKCASGYTGKNC 1266 Score = 39.9 bits (89), Expect = 0.029 Identities = 15/47 (31%), Positives = 24/47 (51%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A T C + ++ C PC N +C + +Y C+C + +TGK C Sbjct: 1258 ASGYTGKNCEQDKNECKVNPCLNNGKCINTPGSYKCNCIDEYTGKHC 1304 Score = 39.1 bits (87), Expect = 0.050 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 10/69 (14%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C GFTG NCE + + C V+ C++G C GG C+ A +T Sbjct: 483 YSCACKAGFTGKNCEQDVNE--CSVNP----CKNGGVC-KNEHGG---YSCACKAGFTGK 532 Query: 1102 VCELRARSF 1110 CE RS+ Sbjct: 533 NCEQECRSY 541 Score = 37.1 bits (82), Expect = 0.20 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095 ++C C GFTG NCE + + S +G +C++ G CV + G + C D Sbjct: 1176 YSCTCKAGFTGKNCEQDVNECSTNPCQNGGVCKNEHGGYSCVCK--AGFTGKNCEQD 1230 Score = 36.7 bits (81), Expect = 0.27 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSIDAAY 1098 ++C C GFTG NCE + + S +G +C++ G C + G + C + AY Sbjct: 23 YSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACK--AGFTGKNC--EQAY 78 Query: 1099 TTA 1101 T A Sbjct: 79 TRA 81 Score = 35.5 bits (78), Expect = 0.62 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 11/71 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C GFTG NCE + + C V+ C++G C GG C+ A +T Sbjct: 300 YSCACKAGFTGKNCEQDVNE--CSVNP----CKNGGVC-KNEHGG---YSCACKAGFTGK 349 Query: 1102 VCELRARSFPV 1112 CE +A S P+ Sbjct: 350 NCE-QAPSKPL 359 Score = 35.5 bits (78), Expect = 0.62 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095 +++C C GFTG NCE + + S +G +C++ G C + G + C D Sbjct: 680 AYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACK--AGFTGKNCEQD 735 Score = 35.5 bits (78), Expect = 0.62 Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095 ++C C GFTG NCE + + S +G +C++ G C + G + + C D Sbjct: 834 YSCTCKAGFTGKNCEQDVNECSENPCKNGGVCKNEHGGYSCACK--AGFMGKNCEQD 888 Score = 35.5 bits (78), Expect = 0.62 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C GFTG NCE + + S +G +C++ + GG C+ A +T Sbjct: 948 YSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKN-------KHGG---YSCACKAGFTGK 997 Query: 1102 VCE 1104 CE Sbjct: 998 NCE 1000 Score = 34.7 bits (76), Expect = 1.1 Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 3/46 (6%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARRE 1084 ++C C GFTG NCE + + S +G +C++ G C + E Sbjct: 986 YSCACKAGFTGKNCEQDVNECSKYPCQNGGVCKNEHGGYSCACKAE 1031 Score = 34.3 bits (75), Expect = 1.4 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095 ++C C GFTG NCE + + S +G +C++ G C + G + C D Sbjct: 719 YSCACKAGFTGKNCEQDVNECSENPCKNGGVCKNEHGGYSCACK--AGFTGKNCEQD 773 Score = 33.5 bits (73), Expect = 2.5 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C FTG NCE + + S +G +C++ GG C+ A +T Sbjct: 1100 YSCACKAEFTGKNCEQDVNECSKNPCKNGGVCKN-------EHGG---YSCTCKAGFTGK 1149 Query: 1102 VCE 1104 +CE Sbjct: 1150 ICE 1152 Score = 33.1 bits (72), Expect = 3.3 Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARRE 1084 ++C C GFTG CE + + S +G +C++ G C + E Sbjct: 1062 YSCTCKAGFTGKTCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAE 1107 Score = 32.3 bits (70), Expect = 5.8 Identities = 16/57 (28%), Positives = 26/57 (45%), Gaps = 5/57 (8%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095 ++C C GF G NCE + + S +G +C++ G C + G + C D Sbjct: 872 YSCACKAGFMGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACK--AGFTGKNCEQD 926 Score = 32.3 bits (70), Expect = 5.8 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 5/57 (8%) Query: 1042 FTCQCPEGFTGVNCETILTKAS---CEVDGDGSICRSGSQCVARREGGILCQGCSID 1095 ++C C GFTG NCE + + S C+ DG G C + G + C D Sbjct: 910 YSCACKAGFTGKNCEQDVNECSKNPCKNDGVCKNEHGGYSCACK--AGFTGKNCEQD 964 Score = 32.3 bits (70), Expect = 5.8 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C FTG NCE + + S +G +C++ GG C+ A +T Sbjct: 1024 YSCACKAEFTGKNCEQDVNECSKNPCKNGGVCKN-------EHGG---YSCTCKAGFTGK 1073 Query: 1102 VCE 1104 CE Sbjct: 1074 TCE 1076 Score = 31.9 bits (69), Expect = 7.6 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C+C G+TG NCE K C+V+ C + +C+ G C C ID YT Sbjct: 1253 YSCKCASGYTGKNCEQ--DKNECKVNP----CLNNGKCI-NTPGSYKC-NC-ID-EYTGK 1302 Query: 1102 VCE 1104 CE Sbjct: 1303 HCE 1305 >SB_16910| Best HMM Match : EGF (HMM E-Value=0) Length = 1552 Score = 53.2 bits (122), Expect = 3e-06 Identities = 56/201 (27%), Positives = 69/201 (34%), Gaps = 31/201 (15%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPC-GAARCVPDQTPKGY 1571 +C+ S C + CV D C C+AG G C C PC +A C+ D+ Y Sbjct: 669 ECLSSPCKNGATCVDRVDGFKCVCDAGYQGSLCQVDRDDCASSPCENSATCI-DRV-DDY 726 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631 C C PGY T C + +C G G D GY C E C+ Sbjct: 727 ECRCAPGY--TGVNC-DHNINDC--GRLNPCQNGGSCIDKLNGYVCSCRPEFTGVECE-- 779 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYAEVTPNSG 1689 P PC + N +C G C C G G C+A N E P Sbjct: 780 --SPVNKCSSNPC------TNNGTCIQGLGIFMCSCPAGFTGPRCEADINE-CESDPCLN 830 Query: 1690 CEVVYDG-------CPRSFAG 1703 DG CP F G Sbjct: 831 SGTCVDGVASFQCKCPVGFTG 851 Score = 49.2 bits (112), Expect = 5e-05 Identities = 17/39 (43%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C++ PC NG +C DL Y C+C EG GK+C Sbjct: 470 CDQNTNECAARPCINGRKCIDLIGDYACECLEGWQGKNC 508 Score = 49.2 bits (112), Expect = 5e-05 Identities = 42/164 (25%), Positives = 56/164 (34%), Gaps = 14/164 (8%) Query: 1511 CQ-SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC-ELGPCGAARCVPD 1565 CQ R DC S C + C+ D C C G G C ++ C L PC D Sbjct: 701 CQVDRDDCASSPCENSATCIDRVDDYECRCAPGYTGVNCDHNINDCGRLNPCQNGGSCID 760 Query: 1566 QTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKE 1622 + GY C+C P +T S + C G C G+ P C + Sbjct: 761 KL-NGYVCSCRPEFTGVECESPVNKCSSNPCTNNGTCIQGLGIFMCSCPAGFTGPRCEAD 819 Query: 1623 NGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663 +C C + +G A C+C G CE C Sbjct: 820 INECESDPCLNSGTCVDGVAS-FQCKC-PVGFTGKRCETKLNHC 861 Score = 49.2 bits (112), Expect = 5e-05 Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 21/209 (10%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C+++ + C+ +C + C+ D + C CE+G VG C V+ C PC D+ Sbjct: 854 CETKLNHCIGHVCANGATCMNGKDKAVCICESGFVGTHCDVNVNECNSMPCQHGGTCIDE 913 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECP-GGWWGGSACGPCACDVTRGYHPHC-NKENG 1624 + C C G T E + C + G++ G H C N + G Sbjct: 914 V-NNFRCLCPTG---TRGHFCEQVIDSCKIAVSFNGTSATKIVDTGVCGAHGTCINIQGG 969 Query: 1625 --KCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRACDACANAY 1681 +C C E + + C + G+ + + + QC CR G G C A + Sbjct: 970 DFRCACDEGYTGNHCHIDIDDCIGHECGNGATCVDGISSYQCICRDGWEGPFCKTMA-SQ 1028 Query: 1682 AEVTP--NSG-CEVVYDG----CPRSFAG 1703 E P N G C+ + D CP ++G Sbjct: 1029 CERNPCQNGGTCQDLDDTFECVCPEGYSG 1057 Score = 49.2 bits (112), Expect = 5e-05 Identities = 18/39 (46%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S+C PC NG C DL DT+ C C EG++G+ C Sbjct: 1022 CKTMASQCERNPCQNGGTCQDLDDTFECVCPEGYSGRTC 1060 Score = 46.0 bits (104), Expect = 4e-04 Identities = 18/39 (46%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C R C+S+PC N A C D D Y C C G+TG +C Sbjct: 701 CQVDRDDCASSPCENSATCIDRVDDYECRCAPGYTGVNC 739 Score = 45.6 bits (103), Expect = 6e-04 Identities = 20/55 (36%), Positives = 29/55 (52%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLR 1371 C+S+PC GA C DL Y C C G GK+C + R+G + + S N ++ Sbjct: 1144 CASSPCQAGAHCLDLIGDYTCVCPPGKIGKNCEVNDPNLCRYGDNQLQSHNTTVK 1198 Score = 45.2 bits (102), Expect = 8e-04 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG-SQCVARREGGILCQGCSID 1095 V SF C+CP GFTG CET L V +G+ C +G + V E G + C ++ Sbjct: 838 VASFQCKCPVGFTGKRCETKLNHCIGHVCANGATCMNGKDKAVCICESGFVGTHCDVN 895 Score = 44.0 bits (99), Expect = 0.002 Identities = 43/182 (23%), Positives = 60/182 (32%), Gaps = 19/182 (10%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAARCVPDQTPK 1569 C C +I +C + W+ TC Q C PC A C+ +T Sbjct: 407 CLHNGSCTNTIEGFQCQCTSDWEGKTC---------QLSKDCHSQPCQNAGTCINTET-- 455 Query: 1570 GYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKC 1626 G+ C C G+ T E C G G AC+ G+ +C++ C Sbjct: 456 GFQCRCAHGWEGPTCDQNTNECAARPCINGRKCIDLIGDYACECLEGWQGKNCDQNINDC 515 Query: 1627 --HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV 1684 CK N + + C C G +C C P + C A N Y V Sbjct: 516 AGQCKHNGTCIDQLND-YTCHC-PLGYTGKNCGLLVDHCLSNPCLNKGICTAVVNGYQCV 573 Query: 1685 TP 1686 P Sbjct: 574 CP 575 Score = 42.7 bits (96), Expect = 0.004 Identities = 46/179 (25%), Positives = 61/179 (34%), Gaps = 23/179 (12%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQ 1566 CQ DC C C+ + C C G GP C + C PC +C+ Sbjct: 433 CQLSKDCHSQPCQNAGTCINTETGFQCRCAHGWEGPTCDQNTNECAARPCINGRKCI--D 490 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN-KENGK 1625 Y+C C G+ C + +C G C D Y HC GK Sbjct: 491 LIGDYACECLEGW--QGKNC-DQNINDCAGQCKHNGTC----IDQLNDYTCHCPLGYTGK 543 Query: 1626 -C-----HCKENHYKPEG--TAECLPCQCYA-AGSENSSCEAATGQCHCRPGVIGRACD 1675 C HC N +G TA QC G ++C+ +C+ P V G D Sbjct: 544 NCGLLVDHCLSNPCLNKGICTAVVNGYQCVCPIGFHGNNCQYKDNECYPNPCVHGSCRD 602 Score = 42.7 bits (96), Expect = 0.004 Identities = 16/39 (41%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C++ PCYNGA C D +C C +G +G DC Sbjct: 1099 CDKNIDDCANNPCYNGATCVDGVGFRLCACAKGFSGPDC 1137 Score = 41.1 bits (92), Expect = 0.012 Identities = 39/141 (27%), Positives = 56/141 (39%), Gaps = 17/141 (12%) Query: 1552 CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV 1611 C PC + P + C C PGYT C E+ + C + G C + Sbjct: 363 CRHLPCQNGGTCFNVGPDQHRCQCHPGYT--GINC-ETRVDSCASNPCLHN--GSCT-NT 416 Query: 1612 TRGYHPHCNKE-NGK-CHC-KENHYKP-EGTAECL------PCQCYAAGSENSSCEAATG 1661 G+ C + GK C K+ H +P + C+ C+C A G E +C+ T Sbjct: 417 IEGFQCQCTSDWEGKTCQLSKDCHSQPCQNAGTCINTETGFQCRC-AHGWEGPTCDQNTN 475 Query: 1662 QCHCRPGVIGRACDACANAYA 1682 +C RP + GR C YA Sbjct: 476 ECAARPCINGRKCIDLIGDYA 496 Score = 41.1 bits (92), Expect = 0.012 Identities = 43/171 (25%), Positives = 56/171 (32%), Gaps = 15/171 (8%) Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568 Q+ DC C C+ + TC C G G C V C PC + + Sbjct: 510 QNINDCA-GQCKHNGTCIDQLNDYTCHCPLGYTGKNCGLLVDHCLSNPC-LNKGICTAVV 567 Query: 1569 KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHC 1628 GY C C G+ + C E P GS C D+ Y C+ +C Sbjct: 568 NGYQCVCPIGFH--GNNCQYKDNECYPNPCVHGS----CR-DLIGDYKCVCSDGYSGRNC 620 Query: 1629 KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 +G C P C G+ QC C PG G C+ N Sbjct: 621 SVPSV--DGNNACNPDPCLH-GAACIFLSDGGSQCQCLPGYTGAFCETNIN 668 Score = 40.7 bits (91), Expect = 0.016 Identities = 18/43 (41%), Positives = 22/43 (51%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T A C + C S+PC NGA C D D + C C G+ G C Sbjct: 659 TGAFCETNINECLSSPCKNGATCVDRVDGFKCVCDAGYQGSLC 701 Score = 39.5 bits (88), Expect = 0.038 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C K + C PC +G+ C DL Y C C +G++G++C+ Sbjct: 583 CQYKDNECYPNPCVHGS-CRDLIGDYKCVCSDGYSGRNCS 621 Score = 38.3 bits (85), Expect = 0.088 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGA-ARCVPDQTPKGY 1571 DC + C + CV C C G GP C + C PC A A C+ Y Sbjct: 1105 DCANNPCYNGATCVDGVGFRLCACAKGFSGPDCRIDIDECASSPCQAGAHCL--DLIGDY 1162 Query: 1572 SCACEPG 1578 +C C PG Sbjct: 1163 TCVCPPG 1169 Score = 37.9 bits (84), Expect = 0.12 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 10/62 (16%) Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103 CQC G+TG CET + + S C++G+ CV R +G C DA Y ++C Sbjct: 652 CQCLPGYTGAFCETNINECL------SSPCKNGATCVDRVDG----FKCVCDAGYQGSLC 701 Query: 1104 EL 1105 ++ Sbjct: 702 QV 703 Score = 37.9 bits (84), Expect = 0.12 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 3/55 (5%) Query: 1297 LNSYVAD---NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 LN YV T C ++CSS PC N C ++C C G TG C Sbjct: 762 LNGYVCSCRPEFTGVECESPVNKCSSNPCTNNGTCIQGLGIFMCSCPAGFTGPRC 816 Score = 37.5 bits (83), Expect = 0.15 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 1/54 (1%) Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 D A T C + C PC NG C D + Y+C C+ TG +C Sbjct: 725 DYECRCAPGYTGVNCDHNINDCGRLNPCQNGGSCIDKLNGYVCSCRPEFTGVEC 778 Score = 37.1 bits (82), Expect = 0.20 Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC N C D ++ C C G TGK C Sbjct: 816 CEADINECESDPCLNSGTCVDGVASFQCKCPVGFTGKRC 854 Score = 36.7 bits (81), Expect = 0.27 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 9/66 (13%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V + C+C G+TGVNC+ + C G + C++G C+ + G + CS + Sbjct: 723 VDDYECRCAPGYTGVNCDHNIN--DC---GRLNPCQNGGSCIDKLNGYV----CSCRPEF 773 Query: 1099 TTAVCE 1104 T CE Sbjct: 774 TGVECE 779 Score = 36.7 bits (81), Expect = 0.27 Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 37/192 (19%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC---GAARCVPDQ--- 1566 DC+ C + CV S C C G GP C S CE PC G + + D Sbjct: 990 DCIGHECGNGATCVDGISSYQCICRDGWEGPFCKTMASQCERNPCQNGGTCQDLDDTFEC 1049 Query: 1567 -TPKGYS---CACEPGYTLT-----TSGCIESGKEE----CPGGWWGGSACGPCACDVTR 1613 P+GYS C + G + + C++ E+ C GW G C D Sbjct: 1050 VCPEGYSGRTCQLDFGQCYSKPCKNNATCVDQVGEQFVCLCRNGW-EGFYCDKNIDDCAN 1108 Query: 1614 G--YH-PHCNKENG--KCHCKENHYKPE---GTAECLPCQCYAAGSENSSCEAATGQ--C 1663 Y+ C G C C + P+ EC C A + C G C Sbjct: 1109 NPCYNGATCVDGVGFRLCACAKGFSGPDCRIDIDECASSPCQAG----AHCLDLIGDYTC 1164 Query: 1664 HCRPGVIGRACD 1675 C PG IG+ C+ Sbjct: 1165 VCPPGKIGKNCE 1176 Score = 36.3 bits (80), Expect = 0.35 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 5/66 (7%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + + C C +G++G NC + + D C G+ C+ +GG CQ C Y Sbjct: 604 IGDYKCVCSDGYSGRNCSVPSVDGNNACNPDP--CLHGAACIFLSDGGSQCQ-CL--PGY 658 Query: 1099 TTAVCE 1104 T A CE Sbjct: 659 TGAFCE 664 Score = 35.5 bits (78), Expect = 0.62 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 10/65 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 F C CP GFTG CE + + CE D C + CV G+ C +T Sbjct: 803 FMCSCPAGFTGPRCEADINE--CESDP----CLNSGTCV----DGVASFQCKCPVGFTGK 852 Query: 1102 VCELR 1106 CE + Sbjct: 853 RCETK 857 Score = 35.5 bits (78), Expect = 0.62 Identities = 14/39 (35%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C K + C C NGA C + D +C C+ G G C Sbjct: 854 CETKLNHCIGHVCANGATCMNGKDKAVCICESGFVGTHC 892 Score = 33.9 bits (74), Expect = 1.9 Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348 C PC NG C ++ D + C C G+TG +C Sbjct: 363 CRHLPCQNGGTCFNVGPDQHRCQCHPGYTGINC 395 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C+ +NG C D + Y C C G+TGK+C Sbjct: 508 CDQNINDCAGQCKHNGT-CIDQLNDYTCHCPLGYTGKNC 545 Score = 33.5 bits (73), Expect = 2.5 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 1283 GCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWD-TYICDCKE 1341 G D D+K + + Y N ++ + + C+ PC +GA C L D C C Sbjct: 598 GSCRDLIGDYKCVCSDGYSGRNCSVPSV-DGNNACNPDPCLHGAACIFLSDGGSQCQCLP 656 Query: 1342 GHTGKDC 1348 G+TG C Sbjct: 657 GYTGAFC 663 Score = 33.1 bits (72), Expect = 3.3 Identities = 11/39 (28%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC + C++ + + C C GK C Sbjct: 395 CETRVDSCASNPCLHNGSCTNTIEGFQCQCTSDWEGKTC 433 Score = 33.1 bits (72), Expect = 3.3 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC +G C D + + C C G G C Sbjct: 892 CDVNVNECNSMPCQHGGTCIDEVNNFRCLCPTGTRGHFC 930 Score = 32.7 bits (71), Expect = 4.4 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 4/51 (7%) Query: 1044 CQCPEGFTGVNCETILTKAS---CEVDGDGSICRSGSQCVARRE-GGILCQ 1090 CQC G+TG+NCET + + C +G + G QC + G CQ Sbjct: 384 CQCHPGYTGINCETRVDSCASNPCLHNGSCTNTIEGFQCQCTSDWEGKTCQ 434 Score = 32.7 bits (71), Expect = 4.4 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSD-LWDTYICDCKEGHTGKDC 1348 C +C S PC N A C D + + ++C C+ G G C Sbjct: 1060 CQLDFGQCYSKPCKNNATCVDQVGEQFVCLCRNGWEGFYC 1099 Score = 31.9 bits (69), Expect = 7.6 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 3/45 (6%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCV 1080 + +TC CP G+TG NC ++ + IC +G QCV Sbjct: 529 LNDYTCHCPLGYTGKNCGLLVDHCLSNPCLNKGICTAVVNGYQCV 573 Score = 31.9 bits (69), Expect = 7.6 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 3/44 (6%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG---SQCVAR 1082 F C C EG+TG +C + G+G+ C G QC+ R Sbjct: 971 FRCACDEGYTGNHCHIDIDDCIGHECGNGATCVDGISSYQCICR 1014 Score = 31.9 bits (69), Expect = 7.6 Identities = 13/32 (40%), Positives = 16/32 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C NGA C D +Y C C++G G C Sbjct: 991 CIGHECGNGATCVDGISSYQCICRDGWEGPFC 1022 >SB_3456| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 462 Score = 53.2 bits (122), Expect = 3e-06 Identities = 20/39 (51%), Positives = 26/39 (66%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 E+ S+C +PC NG ECS+ + Y C C+EG GKDC D Sbjct: 114 EEPSKCHPSPCRNGGECSETEEGYTCLCREGFRGKDCED 152 Score = 39.5 bits (88), Expect = 0.038 Identities = 47/190 (24%), Positives = 66/190 (34%), Gaps = 15/190 (7%) Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPCGAARCVPDQ 1566 D C+ + C S C +C + + TC C G G C ++ C+ PC + +Q Sbjct: 111 DNCEEPSKCHPSPCRNGGECSETEEGYTCLCREGFRGKDCEDLNQCDPNPCKNSGTCFEQ 170 Query: 1567 TPKGYSCACEPGYTLTTSGCI-ESGKEEC-PGGWWGGSACG-PCACDVTRGYHPH-CN-- 1620 + C C Y T + E C GG +A G C C GY + C Sbjct: 171 N-GDFVCNCPKMYRGKTCEVVSECTAARCVNGGSCHDTATGFKCKCPF--GYFGNRCEVY 227 Query: 1621 -KENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 K + Y TA C P C G S C C G G+ C+ + Sbjct: 228 YKTKTGLYSLSATYVSTVTA-CQPNPCLNGGL--CSRFGTQHSCQCARGYSGKHCEEHSP 284 Query: 1680 AYAEVTPNSG 1689 + N G Sbjct: 285 CGTSICMNGG 294 Score = 37.5 bits (83), Expect = 0.15 Identities = 13/34 (38%), Positives = 17/34 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C PC NG CS + C C G++GK C + Sbjct: 248 CQPNPCLNGGLCSRFGTQHSCQCARGYSGKHCEE 281 Score = 34.7 bits (76), Expect = 1.1 Identities = 13/34 (38%), Positives = 17/34 (50%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 S C++A C NG C D + C C G+ G C Sbjct: 191 SECTAARCVNGGSCHDTATGFKCKCPFGYFGNRC 224 Score = 33.1 bits (72), Expect = 3.3 Identities = 11/37 (29%), Positives = 19/37 (51%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E ++C PC N C + ++C+C + + GK C Sbjct: 151 EDLNQCDPNPCKNSGTCFEQNGDFVCNCPKMYRGKTC 187 Score = 31.9 bits (69), Expect = 7.6 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 8/75 (10%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARR-EGGILCQGCSIDAAY 1098 T +CQC G++G +CE + C SIC +G CV C Y Sbjct: 264 TQHSCQCARGYSGKHCE---EHSPCGT----SICMNGGTCVDNTFTNSRYGFACVCPRGY 316 Query: 1099 TTAVCELRARSFPVS 1113 T +CE + VS Sbjct: 317 TGILCEKHRKRNKVS 331 >SB_20264| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 480 Score = 52.8 bits (121), Expect = 4e-06 Identities = 52/201 (25%), Positives = 74/201 (36%), Gaps = 26/201 (12%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C S C CV + +CTC AG G C + C PC D G++ Sbjct: 142 ECKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCETDIDECAGNPCANGGTCKDGI-NGFT 200 Query: 1573 CACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNKENGKCH---C 1628 C C GY +T C E +EC G G+ C + T P N N + + C Sbjct: 201 CECAVGYNGST--C-EIDIDECASGPCQNGATCNDGVNNYTCSCIPGFNGTNCETNIDEC 257 Query: 1629 KENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQC---------HCRPGVIGRACD 1675 + GT C C G ++CE +C C+ G+ G C+ Sbjct: 258 ASGPCQNGGTCNDGVNNYTCLC-IPGFNGTNCETNIDECIGNPCANGGTCKDGINGFTCE 316 Query: 1676 ACANAYAEVTPNSGCEVVYDG 1696 C Y+ T GC++ G Sbjct: 317 -CPVGYSGSTCEIGCDLAAIG 336 Score = 42.7 bits (96), Expect = 0.004 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 7/57 (12%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DGMLSF 1366 C S+PC NG C D + Y C C G TGK+C + G P GG DG+ F Sbjct: 143 CKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCETDIDECAGNPCANGGTCKDGINGF 199 Score = 42.3 bits (95), Expect = 0.005 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC NGA C+D + Y C C G G +C Sbjct: 212 CEIDIDECASGPCQNGATCNDGVNNYTCSCIPGFNGTNC 250 Score = 41.9 bits (94), Expect = 0.007 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 NGT C C+S PC NG C+D + Y C C G G +C Sbjct: 246 NGT--NCETNIDECASGPCQNGGTCNDGVNNYTCLCIPGFNGTNC 288 Score = 39.1 bits (87), Expect = 0.050 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 2/45 (4%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 NGT C C PC NG C D + + C+C G++G C Sbjct: 284 NGT--NCETNIDECIGNPCANGGTCKDGINGFTCECPVGYSGSTC 326 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+ PC NG C D + + C+C G+ G C Sbjct: 174 CETDIDECAGNPCANGGTCKDGINGFTCECAVGYNGSTC 212 Score = 37.5 bits (83), Expect = 0.15 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + ++C C GFTG NCET + + + +G C+ G G C+ C++ Y Sbjct: 158 INRYSCTCVAGFTGKNCETDIDECAGNPCANGGTCKDGI-------NGFTCE-CAV--GY 207 Query: 1099 TTAVCEL 1105 + CE+ Sbjct: 208 NGSTCEI 214 Score = 37.5 bits (83), Expect = 0.15 Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V ++TC C GF G NCET + + G+ C +G C + GI C Y Sbjct: 272 VNNYTCLCIPGFNGTNCETNIDECI------GNPCANGGTC----KDGINGFTCECPVGY 321 Query: 1099 TTAVCEL 1105 + + CE+ Sbjct: 322 SGSTCEI 328 Score = 36.7 bits (81), Expect = 0.27 Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 V ++TC C GF G NCET + + + +G C G Sbjct: 234 VNNYTCSCIPGFNGTNCETNIDECASGPCQNGGTCNDG 271 Score = 31.9 bits (69), Expect = 7.6 Identities = 11/38 (28%), Positives = 19/38 (50%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 + FTC+C G+ G CE + + + +G+ C G Sbjct: 196 INGFTCECAVGYNGSTCEIDIDECASGPCQNGATCNDG 233 >SB_2152| Best HMM Match : EGF (HMM E-Value=0) Length = 1603 Score = 52.8 bits (121), Expect = 4e-06 Identities = 48/190 (25%), Positives = 68/190 (35%), Gaps = 19/190 (10%) Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV----SACELGPC-GAARC 1562 D C+ D C + C YS C+ ++ TC C G C + C+ PC C Sbjct: 9 DYCEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLCDPNPCQNGGVC 68 Query: 1563 VPDQTPKGYSCACEPGYT-LTTSGCIESGKE-ECPGGWW---GGSACGPCACDVTRGYHP 1617 Y+CAC GYT +G + + C G +A C G++ Sbjct: 69 KETFDRNNYTCACPQGYTGWNCNGTLHPCETLNCNNGGTCQKQSNASDDYVCVCVTGFNG 128 Query: 1618 -HCNKENGKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPG--VIG 1671 C + C CK H K C C +G E C+ +C +PG + G Sbjct: 129 IRCEQNIDDCASLPCK--HGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNG 186 Query: 1672 RACDACANAY 1681 CD Y Sbjct: 187 GTCDNYLGTY 196 Score = 47.6 bits (108), Expect = 1e-04 Identities = 47/176 (26%), Positives = 64/176 (36%), Gaps = 16/176 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 CQ D C + C CV + C+C G G +C + C C A + DQ Sbjct: 209 CQENIDECDPNPCLNGGTCVDGINGFNCSCFIGFTGERCETNIDDCVSNTCNANQDCVDQ 268 Query: 1567 TPKGYSCACEPGYTLT--TSGCIESGKEEC-PGGWWGGSACG-PCACDVTRGYHPHCNKE 1622 Y+C C+PGYT + + +E C GG G C C + R HC + Sbjct: 269 V-NNYTCVCKPGYTGSDCSVDILECLSNPCRHGGTCHEGVNGYNCTC-LPRFNGTHCELD 326 Query: 1623 NGKCHCKENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C + GT C C A + CE + CH P G +C Sbjct: 327 TVN-DCNSSPCLNNGTCVDDVGFFNCTCPKA-FDGVRCENKSDSCHPNPCKHGASC 380 Score = 44.4 bits (100), Expect = 0.001 Identities = 39/177 (22%), Positives = 55/177 (31%), Gaps = 14/177 (7%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC+ + C CV ++ TC C+ G G C + C PC C + GY Sbjct: 253 DCVSNTCNANQDCVDQVNNYTCVCKPGYTGSDCSVDILECLSNPCRHGGTC--HEGVNGY 310 Query: 1572 SCACEPGYTLT---TSGCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCH 1627 +C C P + T + C G C + + C ++ CH Sbjct: 311 NCTCLPRFNGTHCELDTVNDCNSSPCLNNGTCVDDVGFFNCTCPKAFDGVRCENKSDSCH 370 Query: 1628 ---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 CK C C G +C+ C P V C N Y Sbjct: 371 PNPCKHGASCAIVNETDFTCAC-PTGYTGKTCDIDIDDCASAPCVANATCVDLLNNY 426 Score = 41.5 bits (93), Expect = 0.009 Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 7/54 (12%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDC---ADSTGP-PWRFGG---DGMLSFN 1367 PC NG C + TY C CK G+ GK+C D P P GG DG+ FN Sbjct: 182 PCLNGGTCDNYLGTYGCSCKAGYRGKNCQENIDECDPNPCLNGGTCVDGINGFN 235 Score = 40.3 bits (90), Expect = 0.022 Identities = 16/44 (36%), Positives = 24/44 (54%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 C C+SAPC++ + C D + Y C C TG+DC+ + G Sbjct: 11 CEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLG 54 Score = 39.9 bits (89), Expect = 0.029 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348 C K C PC +GA C+ + +T + C C G+TGK C Sbjct: 362 CENKSDSCHPNPCKHGASCAIVNETDFTCACPTGYTGKTC 401 Score = 39.5 bits (88), Expect = 0.038 Identities = 15/32 (46%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+SAPC A C DL + Y C C G+ G C Sbjct: 408 CASAPCVANATCVDLLNNYTCKCASGYHGDLC 439 Score = 39.1 bits (87), Expect = 0.050 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C C S C +C D + Y C CK G+TG DC+ + P R GG Sbjct: 247 CETNIDDCVSNTCNANQDCVDQVNNYTCVCKPGYTGSDCSVDILECLSNPCRHGG 301 Score = 38.7 bits (86), Expect = 0.066 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354 C PC NG C + +D Y C C +G+TG +C + P Sbjct: 57 CDPNPCQNGGVCKETFDRNNYTCACPQGYTGWNCNGTLHP 96 Score = 37.5 bits (83), Expect = 0.15 Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E C PC NG C D + + C C G TG+ C Sbjct: 209 CQENIDECDPNPCLNGGTCVDGINGFNCSCFIGFTGERC 247 Score = 34.7 bits (76), Expect = 1.1 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 14/105 (13%) Query: 1002 CVHEPCLNFEEC-LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILT 1060 C P N C L + N+S +N+ + + V F C CP+ F GV CE Sbjct: 312 CTCLPRFNGTHCELDTVNDCNSSPCLNNGTC----VDDVGFFNCTCPKAFDGVRCEN--K 365 Query: 1061 KASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105 SC + C+ G+ C E C+ YT C++ Sbjct: 366 SDSCHPNP----CKHGASCAIVNETDFT---CACPTGYTGKTCDI 403 Score = 33.5 bits (73), Expect = 2.5 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS 1077 ++TC CP+G+TG NC L +G C+ S Sbjct: 76 NYTCACPQGYTGWNCNGTLHPCETLNCNNGGTCQKQS 112 Score = 33.5 bits (73), Expect = 2.5 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 3/45 (6%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC 1557 DC + C + CV ++ TC C +G G C ++ CE PC Sbjct: 407 DCASAPCVANATCVDLLNNYTCKCASGYHGDLCQFDINECESNPC 451 >SB_13309| Best HMM Match : EGF (HMM E-Value=0) Length = 718 Score = 52.0 bits (119), Expect = 7e-06 Identities = 56/214 (26%), Positives = 81/214 (37%), Gaps = 35/214 (16%) Query: 1513 SRADCMLSICPPYSKCVTSWDSST---CTCEAGRVGPQC---VSAC-ELGPCGAARCVPD 1565 +++ C + C KC + C C +G G +C V+ C PC V Sbjct: 341 TKSPCSPNPCENGGKCADDLGQDSGYRCVCRSGFSGARCQSDVNECASSNPCKNGG-VCT 399 Query: 1566 QTPKGYSCACEPGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHC 1619 +P GYSC C GYT + C S C G ++ G +C GY +C Sbjct: 400 NSPGGYSCKCASGYTGKNCEKDVNECASS--NPCKNGGVCTNSPGGYSCKCASGYTGKNC 457 Query: 1620 NKENGKCHCKENHYKPEGTAECLP----CQCYAAGSENSSCEAATGQC----HCRPGVI- 1670 K+ +C N K G P C+C A+G +CE +C C+ G + Sbjct: 458 EKDVNEC-ASSNPCKNGGVCTNSPGGYSCKC-ASGYTGKNCEKDVNECASSNPCKNGGVC 515 Query: 1671 ----GRACDACANAYAEVTPNSGCEVVYDGCPRS 1700 GR CA+ Y CE+ + C S Sbjct: 516 ANSPGRYSCECASGYT----GKNCEIDVNECASS 545 Score = 45.2 bits (102), Expect = 8e-04 Identities = 17/47 (36%), Positives = 25/47 (53%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A T C + +C +PC NG +C + Y C+CK G++GK C Sbjct: 566 ASGYTGKNCEKDEDKCKVSPCQNGGKCINSDGGYSCECKGGYSGKHC 612 Score = 42.7 bits (96), Expect = 0.004 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A T C + + C+S+ PC NG C++ Y C+C G+TGK+C Sbjct: 488 ASGYTGKNCEKDVNECASSNPCKNGGVCANSPGRYSCECASGYTGKNC 535 Score = 41.9 bits (94), Expect = 0.007 Identities = 38/125 (30%), Positives = 49/125 (39%), Gaps = 16/125 (12%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC-ELGPCGAARCVPDQTPKGYSCACEP 1577 C C S +C C +G G C V+ C PC V +P GYSC C Sbjct: 509 CKNGGVCANSPGRYSCECASGYTGKNCEIDVNECASSNPCKNGG-VCTNSPGGYSCKCAS 567 Query: 1578 GYTLTTSGCIESGKEECP-GGWWGGSAC----GPCACDVTRGYH-PHC-NKENGKCHC-K 1629 GY T C E +++C G C G +C+ GY HC + C K Sbjct: 568 GY--TGKNC-EKDEDKCKVSPCQNGGKCINSDGGYSCECKGGYSGKHCETAKYASLGCFK 624 Query: 1630 ENHYK 1634 +NH K Sbjct: 625 DNHKK 629 Score = 41.1 bits (92), Expect = 0.012 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 1308 AGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A C + C+S+ PC NG C++ Y C C G+TGK+C Sbjct: 377 ARCQSDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 418 Score = 41.1 bits (92), Expect = 0.012 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A T C + + C+S+ PC NG C++ Y C C G+TGK+C Sbjct: 410 ASGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 457 Score = 41.1 bits (92), Expect = 0.012 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A T C + + C+S+ PC NG C++ Y C C G+TGK+C Sbjct: 449 ASGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 496 Score = 39.5 bits (88), Expect = 0.038 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A T C + C+S+ PC NG C++ Y C C G+TGK+C Sbjct: 527 ASGYTGKNCEIDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 574 Score = 37.5 bits (83), Expect = 0.15 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C+C G+TG NCE + C+V S C++G +C+ +GG C+ C Y+ Sbjct: 561 YSCKCASGYTGKNCEK--DEDKCKV----SPCQNGGKCI-NSDGGYSCE-CK--GGYSGK 610 Query: 1102 VCE 1104 CE Sbjct: 611 HCE 613 Score = 35.9 bits (79), Expect = 0.47 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 8/72 (11%) Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSD---LWDTYI 1336 DF G D + H++ D +++ N P K S CS PC NG +C+D Y Sbjct: 313 DFNGDGEDDLLCHRYSDGYKWISYNRY----PTK-SPCSPNPCENGGKCADDLGQDSGYR 367 Query: 1337 CDCKEGHTGKDC 1348 C C+ G +G C Sbjct: 368 CVCRSGFSGARC 379 Score = 35.1 bits (77), Expect = 0.82 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 9/63 (14%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C+C G+TG NCE + + + + C++G C GG C+ C+ + YT Sbjct: 522 YSCECASGYTGKNCEIDVNECA-----SSNPCKNGGVC-TNSPGGYSCK-CA--SGYTGK 572 Query: 1102 VCE 1104 CE Sbjct: 573 NCE 575 Score = 34.7 bits (76), Expect = 1.1 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 9/63 (14%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C+C G+TG NCE + + + + C++G C GG C+ C+ + YT Sbjct: 405 YSCKCASGYTGKNCEKDVNECA-----SSNPCKNGGVC-TNSPGGYSCK-CA--SGYTGK 455 Query: 1102 VCE 1104 CE Sbjct: 456 NCE 458 Score = 34.3 bits (75), Expect = 1.4 Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 9/64 (14%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C+C G+TG NCE + + + + C++G C A G C+ C+ + YT Sbjct: 483 YSCKCASGYTGKNCEKDVNECA-----SSNPCKNGGVC-ANSPGRYSCE-CA--SGYTGK 533 Query: 1102 VCEL 1105 CE+ Sbjct: 534 NCEI 537 >SB_16967| Best HMM Match : Laminin_EGF (HMM E-Value=0) Length = 1706 Score = 52.0 bits (119), Expect = 7e-06 Identities = 44/149 (29%), Positives = 64/149 (42%), Gaps = 32/149 (21%) Query: 1549 VSACELGPCGAARCVPDQTPKGY--SCACEPGYTLTTSGCIESGKEECPGGWWGGSA--- 1603 V+AC LG C+ T C+C+P + C ++C G WG + Sbjct: 393 VNAC-LGITNNGSCLTQATDTEQIGQCSCKPN--VYGRRC-----DQCIPGHWGFTLPPQ 444 Query: 1604 --CGPCACDV--TRGYHPHCNKENGKCHCKEN-------------HYKP-EGTAECLPCQ 1645 C C C++ TR +C++ G+C CK + H P +G C PCQ Sbjct: 445 GECKACNCNISGTRNATINCDQLTGQCFCKPSIQGVYCDGCRDGFHTFPTQGDGGCAPCQ 504 Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C G S C+ ++G C CR GV G +C Sbjct: 505 CDLGGGF-SICDKSSGSCTCRKGVEGFSC 532 Score = 50.4 bits (115), Expect = 2e-05 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 12/83 (14%) Query: 1607 CACDVTRGYHP-HCNKENGKCHCKE-------NHYKPE----GTAECLPCQCYAAGSENS 1654 C CD +P C G+C CK NH P + C C+C +GS Sbjct: 738 CECDPEGSTNPTQCVAYGGQCPCKPGVAGLKCNHCLPGYYALSRSGCKKCECSMSGSITP 797 Query: 1655 SCEAATGQCHCRPGVIGRACDAC 1677 C+ A G+C C+ V G CDAC Sbjct: 798 ICDNADGKCQCKANVEGAKCDAC 820 Score = 48.4 bits (110), Expect = 8e-05 Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 4/49 (8%) Query: 1635 PEGTAECLPCQCYAAGSENSS--CEAATGQCHCRPGVIGRACDACANAY 1681 P+G EC C C +G+ N++ C+ TGQC C+P + G CD C + + Sbjct: 443 PQG--ECKACNCNISGTRNATINCDQLTGQCFCKPSIQGVYCDGCRDGF 489 Score = 47.2 bits (107), Expect = 2e-04 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 1620 NKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN-SSCEAATGQCHCRPGVIGRACDACA 1678 N EN +C E C+C GS N + C A GQC C+PGV G C+ C Sbjct: 714 NTENPQCRALVFSASTELYNGTKVCECDPEGSTNPTQCVAYGGQCPCKPGVAGLKCNHCL 773 Query: 1679 NAYAEVTPNSGCE 1691 Y ++ SGC+ Sbjct: 774 PGYYALS-RSGCK 785 Score = 42.3 bits (95), Expect = 0.005 Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 20/154 (12%) Query: 1552 CELGPCGAARCVPDQ-TPKGYSCACEPGYT-LTTSGCIESGKEECPGGW-WGGSACGPCA 1608 CE P G+ P Q G C C+PG L + C+ PG + S C C Sbjct: 738 CECDPEGSTN--PTQCVAYGGQCPCKPGVAGLKCNHCL-------PGYYALSRSGCKKCE 788 Query: 1609 CDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ--CYAAGSEN-SSCEAATGQCHC 1665 C ++ P C+ +GKC CK N EG A+C C+ + S N C+ G H Sbjct: 789 CSMSGSITPICDNADGKCQCKAN---VEG-AKCDACKYGTFHLDSGNPHGCQHCFGYGHA 844 Query: 1666 RPGVIGRACDACANAYAEVTPNSGCEVV-YDGCP 1698 A +T + G VV Y G P Sbjct: 845 HNCTSASGFIATNITSNFITGSDGWTVVDYSGIP 878 Score = 38.3 bits (85), Expect = 0.088 Identities = 37/135 (27%), Positives = 48/135 (35%), Gaps = 13/135 (9%) Query: 1555 GPCGAARCVPDQTPKGYSCA-CEPGYTLTT-SGCIESGKEECPGGWWGGSACGPCACDVT 1612 GP + RC + G C CEP + ++ EC A C + T Sbjct: 299 GPIMSRRCECEHNTMGTDCEMCEPLFNNRPWMRANQTHGNECQECNCNNHATS-CVYNET 357 Query: 1613 RGYH--PHC--NKENGKC-HCKENHYKPEGTAECLPCQCYAAGSENSSCEAAT-----GQ 1662 GY C N + C +C HY+ C + S AT GQ Sbjct: 358 LGYGLCKGCQHNTQGDHCQNCTAKHYRDLSKPINHVNACLGITNNGSCLTQATDTEQIGQ 417 Query: 1663 CHCRPGVIGRACDAC 1677 C C+P V GR CD C Sbjct: 418 CSCKPNVYGRRCDQC 432 Score = 36.3 bits (80), Expect = 0.35 Identities = 30/89 (33%), Positives = 38/89 (42%), Gaps = 13/89 (14%) Query: 1605 GPCA-CDV-TRGYHPH-C--NKENGKC-HCKENHYKPEGTAECLPCQCYAAG---SENSS 1655 G C C + T GY C N + +C CK ++ C C C G S S Sbjct: 1022 GVCTDCKIGTHGYRCELCTNNVQGPECVRCKPQYWGLSKDG-CKACDCNLPGTLYSNTSV 1080 Query: 1656 CEAATGQCHCRP--GVIGRACDAC-ANAY 1681 C+ TGQC C + G+ CD C NAY Sbjct: 1081 CDQTTGQCSCNATLHIGGQLCDRCEENAY 1109 >SB_8425| Best HMM Match : EGF (HMM E-Value=0) Length = 1955 Score = 52.0 bits (119), Expect = 7e-06 Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 5/71 (7%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC + C CV + TCTC+AG G +C V C PC C GY Sbjct: 587 DCAKNPCLNNGACVDQVNGYTCTCKAGFAGSRCDRNVDNCYPNPCVNGVC--KNKVNGYE 644 Query: 1573 CACEPGYTLTT 1583 CAC PGY+ +T Sbjct: 645 CACNPGYSGST 655 Score = 50.8 bits (116), Expect = 2e-05 Identities = 60/237 (25%), Positives = 75/237 (31%), Gaps = 20/237 (8%) Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS---ACELGPCGAARCVPD 1565 D C +C S C +C + D C C G G +C + C PC D Sbjct: 428 DMCLDIDNCASSPCQNGGRCESLKDDFRCACPGGFTGRRCETEQDECLSDPCYQGSTCID 487 Query: 1566 QTPKGYSCACEPGYTLTTSGCIES--GKEECPGGWWGGSACGPCACDVTRGYHP-HCNKE 1622 + GY C C GY+ I C G + AC+ GY C ++ Sbjct: 488 KV-NGYECICAAGYSGPNCDVISGLCSSSRCQNGAKCVAKPPSGACECPEGYGGLFCERK 546 Query: 1623 NGKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 C CK N + C C G CE C P + AC N Sbjct: 547 MDFCVSAPCK-NGGLCRSLQDKFQCNC-RPGFSGDRCEIDIDDCAKNPCLNNGACVDQVN 604 Query: 1680 AYAEVT----PNSGCEVVYDGC-PRSFAGGVWWPRTKFGVETITDCPPGSSGRATRT 1731 Y S C+ D C P GV + G E C PG SG T Sbjct: 605 GYTCTCKAGFAGSRCDRNVDNCYPNPCVNGVCKNKVN-GYECA--CNPGYSGSTCAT 658 Score = 44.4 bits (100), Expect = 0.001 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C K C SAPC NG C L D + C+C+ G +G C Sbjct: 543 CERKMDFCVSAPCKNGGLCRSLQDKFQCNCRPGFSGDRC 581 Score = 42.3 bits (95), Expect = 0.005 Identities = 15/32 (46%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S+PC NG C L D + C C G TG+ C Sbjct: 436 CASSPCQNGGRCESLKDDFRCACPGGFTGRRC 467 Score = 42.3 bits (95), Expect = 0.005 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C ++ C S PCY G+ C D + Y C C G++G +C Sbjct: 467 CETEQDECLSDPCYQGSTCIDKVNGYECICAAGYSGPNC 505 Score = 40.7 bits (91), Expect = 0.016 Identities = 17/51 (33%), Positives = 24/51 (47%) Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355 G P + C S C NG C DL + + C C G+ G+ C ++G P Sbjct: 1096 GCKESVPVAKGTCVSNSCTNGGTCVDLPNEFKCVCPSGYEGRRCEHASGCP 1146 Score = 40.7 bits (91), Expect = 0.016 Identities = 46/171 (26%), Positives = 64/171 (37%), Gaps = 30/171 (17%) Query: 1538 TCEAGR-VG--PQCVSACELG----PCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESG 1590 TC GR G PQCV E PC A +C T ++C+C PGY L + G + Sbjct: 1185 TCNHGRWTGNDPQCVDINECNSASSPC-AQQCT--NTEGSFTCSCNPGYNLGSDGVTCND 1241 Query: 1591 KEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECL---PCQCY 1647 EC S G C+ + + K + +C C G C C Sbjct: 1242 VNEC-------SLTGICS------HKCYNTKGSFRCECPAGMELAAGGRSCQDKDECAIQ 1288 Query: 1648 AAGSENSSCEA-ATGQCHCRPGV-IGRACDACANAYAEVT--PNSGCEVVY 1694 G E++ C CR G + +CA + VT P G E ++ Sbjct: 1289 NGGCEHACANGYLRSTCQCRGGYNLESDIRSCAEIHCPVTTPPTGGKETIH 1339 Score = 38.3 bits (85), Expect = 0.088 Identities = 40/152 (26%), Positives = 49/152 (32%), Gaps = 14/152 (9%) Query: 1565 DQTPKGYSCA--CEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620 D+ SC C+PGY +T + C + E G C PC T + Sbjct: 314 DEAKNFTSCTEKCKPGYYSSTGLARCTICPRGEYASGHMN-KKCAPCPQGTTTVLAAATS 372 Query: 1621 KENGKCHCKENHYKPEGTAECLPCQ--CYAAGSENSSCEAATGQCHCR-PGVIGR-ACDA 1676 +E C Y G CLPC Y SC G PG C Sbjct: 373 REECGMMCAPGTYSSSGVEPCLPCPKGTYQTAIGQMSCSECPGTKSTHGPGADSHDMCLD 432 Query: 1677 CANAYAEVTPNSG-CEVVYD----GCPRSFAG 1703 N + N G CE + D CP F G Sbjct: 433 IDNCASSPCQNGGRCESLKDDFRCACPGGFTG 464 Score = 37.1 bits (82), Expect = 0.20 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 11/85 (12%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V + C C G++G NC+ I C S C++G++CVA+ G C Y Sbjct: 489 VNGYECICAAGYSGPNCDVI--SGLC----SSSRCQNGAKCVAKPPSG----ACECPEGY 538 Query: 1099 TTAVCELRARSFPVSSFLTFPGLKR 1123 CE R F VS+ GL R Sbjct: 539 GGLFCE-RKMDFCVSAPCKNGGLCR 562 Score = 36.3 bits (80), Expect = 0.35 Identities = 13/32 (40%), Positives = 15/32 (46%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ PC N C D + Y C CK G G C Sbjct: 588 CAKNPCLNNGACVDQVNGYTCTCKAGFAGSRC 619 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSS+ C NGA+C + C+C EG+ G C Sbjct: 512 CSSSRCQNGAKCVAKPPSGACECPEGYGGLFC 543 Score = 34.3 bits (75), Expect = 1.4 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 10/64 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 F C CP GFTG CET + C D C GS C+ + G C A Y+ Sbjct: 454 FRCACPGGFTGRRCET--EQDECLSDP----CYQGSTCIDKVNG----YECICAAGYSGP 503 Query: 1102 VCEL 1105 C++ Sbjct: 504 NCDV 507 Score = 34.3 bits (75), Expect = 1.4 Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C PC NG C + + Y C C G++G CA Sbjct: 619 CDRNVDNCYPNPCVNGV-CKNKVNGYECACNPGYSGSTCA 657 Score = 34.3 bits (75), Expect = 1.4 Identities = 34/150 (22%), Positives = 53/150 (35%), Gaps = 20/150 (13%) Query: 1513 SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPCGAARCVPDQTPKG 1570 ++ C+ + C CV + C C +G G +C S C + T G Sbjct: 1104 AKGTCVSNSCTNGGTCVDLPNEFKCVCPSGYEGRRCEHASGCPSPKSPTNGKIVSSTGSG 1163 Query: 1571 Y----SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 + + C G+ LT G C G W G+ P D+ CN + C Sbjct: 1164 HGSSVTVTCNAGFKLTGDGV-----RTCNHGRWTGN--DPQCVDIN-----ECNSASSPC 1211 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSC 1656 + + + T C P Y GS+ +C Sbjct: 1212 AQQCTNTEGSFTCSCNP--GYNLGSDGVTC 1239 >SB_59261| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 5445 Score = 51.6 bits (118), Expect = 9e-06 Identities = 19/38 (50%), Positives = 24/38 (63%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 CSS PC NG C+D+ D Y C C+EG TG++C P Sbjct: 1620 CSSTPCRNGGTCNDIVDGYKCTCQEGKTGRNCEFDDSP 1657 Score = 44.0 bits (99), Expect = 0.002 Identities = 19/65 (29%), Positives = 30/65 (46%) Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343 C+++ D + T C +++ CSS PC NG C+ Y C+C G+ Sbjct: 2590 CMNEAKCTEMIRDFQCECSAEFTGKNCELRKTNCSSNPCQNGGTCNVTDTGYKCECFVGY 2649 Query: 1344 TGKDC 1348 GK+C Sbjct: 2650 IGKEC 2654 Score = 41.9 bits (94), Expect = 0.007 Identities = 24/73 (32%), Positives = 28/73 (38%), Gaps = 5/73 (6%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPC-GAARCVPDQ 1566 CQ A C + C C D CTC+ G+ G C S C PC C Sbjct: 1614 CQVMAPCSSTPCRNGGTCNDIVDGYKCTCQEGKTGRNCEFDDSPCASSPCKNGGNCTKVD 1673 Query: 1567 TPKGYSCACEPGY 1579 K Y CAC G+ Sbjct: 1674 DVK-YECACALGF 1685 Score = 41.1 bits (92), Expect = 0.012 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 7/85 (8%) Query: 1502 TVRENVRDG-CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV--SACELGPCG 1558 ++ + +RD C + C LS C C+ TCTC +G G C C L Sbjct: 4386 SIVDKLRDQICIASHPCALSPCKNGGFCLGDLSGYTCTCASGWTGVNCEIRDFCALASVN 4445 Query: 1559 AARC----VPDQTPKGYSCACEPGY 1579 C V TP Y+C C G+ Sbjct: 4446 GPACFNGGVCTNTPTSYTCTCARGF 4470 Score = 40.3 bits (90), Expect = 0.022 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDCADST 1352 C S C+S+PC NG C+ + D Y C C G G +C D+T Sbjct: 1651 CEFDDSPCASSPCKNGGNCTKVDDVKYECACALGFRGINCEDAT 1694 Score = 39.9 bits (89), Expect = 0.029 Identities = 16/44 (36%), Positives = 21/44 (47%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 C + S C SAPC NGA C+ ++ C C + G C G Sbjct: 1690 CEDATSTCDSAPCQNGATCTPTNTSFQCACLVEYAGNTCEKLCG 1733 Score = 39.5 bits (88), Expect = 0.038 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDC-KEGHTGKDCAD 1350 E ++ CS APC NG C++ D + C+C G TG C + Sbjct: 3619 EAKAPCSGAPCKNGGICTENGDLFNCNCTSTGFTGPTCEE 3658 Score = 39.5 bits (88), Expect = 0.038 Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S+PC NG CS L Y+C C + G C Sbjct: 5004 CASSPCKNGGTCSKLSSGYVCKCTKQFNGSRC 5035 Score = 39.1 bits (87), Expect = 0.050 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E C C N A C + ++ CDCKEG+TG C Sbjct: 4781 CGEDVDECYHMLCKNDALCINTLGSFKCDCKEGYTGLTC 4819 Score = 38.3 bits (85), Expect = 0.088 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 3/35 (8%) Query: 1317 CSSAPCYNGAECSD---LWDTYICDCKEGHTGKDC 1348 CSS+PC N C++ + Y C C G TGKDC Sbjct: 492 CSSSPCNNNGNCTNKVAIPGDYSCACHTGFTGKDC 526 Score = 38.3 bits (85), Expect = 0.088 Identities = 13/32 (40%), Positives = 20/32 (62%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S PC N A+C+++ + C+C TGK+C Sbjct: 2585 CESNPCMNEAKCTEMIRDFQCECSAEFTGKNC 2616 Score = 36.3 bits (80), Expect = 0.35 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Query: 1288 FYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKD 1347 F++++ ++L +Y + C + R C PC+NGA+C + + C C G G+ Sbjct: 5387 FHVEYSGLNLIAYAIRDRI---CID-RDECIGNPCFNGAKCVNTASGFTCMCAPGFYGQY 5442 Query: 1348 C 1348 C Sbjct: 5443 C 5443 Score = 35.9 bits (79), Expect = 0.47 Identities = 13/32 (40%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ +PC NGA C + Y C C +TG++C Sbjct: 753 CALSPCKNGATCFRQNNDYTCKCPITYTGRNC 784 Score = 35.5 bits (78), Expect = 0.62 Identities = 13/33 (39%), Positives = 15/33 (45%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 +C+ PC NG C D C C H GK C Sbjct: 3067 KCTPNPCKNGGTCIDRGYRNYCKCPVSHVGKSC 3099 Score = 35.1 bits (77), Expect = 0.82 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 9/62 (14%) Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103 C CP FTGV+CET K C + CR+G C I C+ Y +C Sbjct: 1152 CNCPGDFTGVHCET--NKDEC---NEAMPCRNGGSCY----NSIGFFNCTCTNQYVGKLC 1202 Query: 1104 EL 1105 E+ Sbjct: 1203 EV 1204 Score = 35.1 bits (77), Expect = 0.82 Identities = 13/40 (32%), Positives = 20/40 (50%) Query: 1311 PEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 P + C C NG C ++ +Y C+C ++GK C D Sbjct: 2244 PVRVDSCIDKTCSNGGRCINITYSYSCECPLVYSGKHCDD 2283 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/45 (31%), Positives = 17/45 (37%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 C R C PC NG C +L + C C + G C P Sbjct: 75 CEYDRDECIGKPCSNGGTCVNLKGGFDCICPANYIGLHCLQVLNP 119 Score = 34.3 bits (75), Expect = 1.4 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 15/64 (23%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C GFTG +CE + C+ +G C S S + C+ A +T + Sbjct: 513 YSCACHTGFTGKDCEIVKDSCGCQ---NGGTCNSTS------------RSCTCPAMFTGS 557 Query: 1102 VCEL 1105 +CE+ Sbjct: 558 ICEI 561 Score = 34.3 bits (75), Expect = 1.4 Identities = 13/32 (40%), Positives = 16/32 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CS +PC NG CS +C+C TG C Sbjct: 1132 CSVSPCLNGGTCSTNGKLAVCNCPGDFTGVHC 1163 Score = 34.3 bits (75), Expect = 1.4 Identities = 13/32 (40%), Positives = 16/32 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ +PC NG C Y C C G TG +C Sbjct: 4402 CALSPCKNGGFCLGDLSGYTCTCASGWTGVNC 4433 Score = 33.9 bits (74), Expect = 1.9 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079 ++ +TC C G+TGVNCE A V+G C +G C Sbjct: 4417 LSGYTCTCASGWTGVNCEIRDFCALASVNGPA--CFNGGVC 4455 Score = 33.5 bits (73), Expect = 2.5 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E S C S PC NG C+++ + C C G C Sbjct: 1913 CRESDS-CYSLPCLNGGTCTNIGGRFNCTCLSAFVGDMC 1950 Score = 32.7 bits (71), Expect = 4.4 Identities = 28/107 (26%), Positives = 34/107 (31%), Gaps = 10/107 (9%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYS 1572 C + C +KC C C A G C + C PC C + T GY Sbjct: 2585 CESNPCMNEAKCTEMIRDFQCECSAEFTGKNCELRKTNCSSNPCQNGGTC--NVTDTGYK 2642 Query: 1573 CACEPGY----TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615 C C GY S G + C G S C+ T Y Sbjct: 2643 CECFVGYIGKECENVSSVDNCGNQTCSGRGNCISQVSSYLCNCTTDY 2689 Score = 32.7 bits (71), Expect = 4.4 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 3/44 (6%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKAS---CEVDGDGSICRSGSQC 1079 + F C+C FTG NCE T S C+ G ++ +G +C Sbjct: 2600 IRDFQCECSAEFTGKNCELRKTNCSSNPCQNGGTCNVTDTGYKC 2643 Score = 32.3 bits (70), Expect = 5.8 Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+ A PC NG C + + C C + GK C Sbjct: 1163 CETNKDECNEAMPCRNGGSCYNSIGFFNCTCTNQYVGKLC 1202 Score = 32.3 bits (70), Expect = 5.8 Identities = 10/32 (31%), Positives = 16/32 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C C +Y+C+C ++GKDC Sbjct: 2663 CGNQTCSGRGNCISQVSSYLCNCTTDYSGKDC 2694 Score = 32.3 bits (70), Expect = 5.8 Identities = 11/32 (34%), Positives = 16/32 (50%) Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 C+NG C++ +Y C C G G+ C G Sbjct: 4449 CFNGGVCTNTPTSYTCTCARGFHGRRCEAGCG 4480 Score = 31.9 bits (69), Expect = 7.6 Identities = 16/50 (32%), Positives = 22/50 (44%), Gaps = 2/50 (4%) Query: 1505 ENVRDG-CQSRADCMLSICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSAC 1552 E +RD C+++A C + C C + D C C G GP C C Sbjct: 3611 EMLRDSICEAKAPCSGAPCKNGGICTENGDLFNCNCTSTGFTGPTCEEPC 3660 >SB_28495| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 6753 Score = 51.2 bits (117), Expect = 1e-05 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 7/124 (5%) Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGA 1559 V++ + CQ C C C S S TC C + +G C + C PC Sbjct: 3828 VKQTKMELCQVADQCSSYPCKNGGTCTNSGQSYTCNCTSDYIGEHCEEKIDPCNPTPCQN 3887 Query: 1560 ARCVPDQTPKGYSCACEPGYT--LTTSGCIESGKEE-CPGGWWGGSACGPCACDVTRGYH 1616 + Y+C C PGYT T+ E + C G + G +C+ + Y Sbjct: 3888 GGTCASPSSSNYTCTCAPGYTGENCTNNVNECNDPDLCKNGGVCKDSFGSYSCNCSSAYS 3947 Query: 1617 -PHC 1619 HC Sbjct: 3948 GKHC 3951 Score = 44.4 bits (100), Expect = 0.001 Identities = 16/33 (48%), Positives = 21/33 (63%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 +CSS PC NG C++ +YIC C TGK+C Sbjct: 3058 QCSSYPCKNGGSCANSGSSYICTCTSEFTGKNC 3090 Score = 44.0 bits (99), Expect = 0.002 Identities = 28/98 (28%), Positives = 34/98 (34%), Gaps = 6/98 (6%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQT 1567 CQ C C C S S CTC + G C AC PCG + Sbjct: 3053 CQVADQCSSYPCKNGGSCANSGSSYICTCTSEFTGKNCEIVRDACNPTPCGNGATCNILS 3112 Query: 1568 PKGYSCACEPGYTLTTSGCIESGKE-ECPGGWWGGSAC 1604 Y+C C GY T C ++ E + P G C Sbjct: 3113 AVNYTCTCAVGY--TGKNCTQNVNECDDPARCQNGGTC 3148 Score = 43.2 bits (97), Expect = 0.003 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDCADS 1351 C EK C+ PC NG C S Y C C G+TG++C ++ Sbjct: 3873 CEEKIDPCNPTPCQNGGTCASPSSSNYTCTCAPGYTGENCTNN 3915 Score = 41.9 bits (94), Expect = 0.007 Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDCADS 1351 C R C+ PC NGA C+ L Y C C G+TGK+C + Sbjct: 3090 CEIVRDACNPTPCGNGATCNILSAVNYTCTCAVGYTGKNCTQN 3132 Score = 41.9 bits (94), Expect = 0.007 Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CS +PC NG C+ + + Y C C++G GK C Sbjct: 3582 CSKSPCLNGGTCTIVGEDYNCTCRQGLIGKQC 3613 Score = 41.9 bits (94), Expect = 0.007 Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 +CSS PC NG C++ +Y C+C + G+ C + P Sbjct: 3841 QCSSYPCKNGGTCTNSGQSYTCNCTSDYIGEHCEEKIDP 3879 Score = 41.5 bits (93), Expect = 0.009 Identities = 17/41 (41%), Positives = 21/41 (51%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 E C + PC NG C +L Y CDC +TGK+C T Sbjct: 2573 EDVDECFNDPCTNGGACINLPGDYECDCPNKYTGKNCEKRT 2613 Score = 41.1 bits (92), Expect = 0.012 Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 8/91 (8%) Query: 1546 PQCVSACELGPCGA-ARCVPDQTPKGYSCACEPGYTLTTSGCI-ESGKEECPGGWWGGSA 1603 P C+ PCGA A C + Y+CAC+PGY I E + C G + Sbjct: 333 PVSFEPCDSKPCGAGATCTHNLVAWNYTCACKPGYYGDNCADIDECTNKPCLNGGSCTNL 392 Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634 G C GY C K C + N+YK Sbjct: 393 QGDYRCSCVSGY---CGK---YCQSRCNNYK 417 Score = 41.1 bits (92), Expect = 0.012 Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C++ PC NG C++L Y C C G+ GK C Sbjct: 378 CTNKPCLNGGSCTNLQGDYRCSCVSGYCGKYC 409 Score = 40.7 bits (91), Expect = 0.016 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSS-APCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C A C NG C DL +Y C C H G+DC Sbjct: 3129 CTQNVNECDDPARCQNGGTCQDLHGSYNCKCSPLHAGRDC 3168 Score = 40.3 bits (90), Expect = 0.022 Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 +C++ PC N C+ ++ + C C G GKDC+ Sbjct: 4731 KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 4764 Score = 39.9 bits (89), Expect = 0.029 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 6/60 (10%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG-GILCQGCSIDAAYTT 1100 ++CQC G+TG +CE+ + + C V G +C S +C+ +G G LC G +A T+ Sbjct: 621 YSCQCLAGYTGQHCESDVDE--CLVPG---VCSSPKECINSIDGYGCLCPGMKFNANCTS 675 Score = 39.9 bits (89), Expect = 0.029 Identities = 15/34 (44%), Positives = 20/34 (58%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 +C+ PC NGA C + + C C G TGKDC+ Sbjct: 4142 KCALDPCKNGATCHNGPRDFTCTCVNGFTGKDCS 4175 Score = 39.5 bits (88), Expect = 0.038 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 4/54 (7%) Query: 1296 DLNSYV-ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 DL+ + A +G L+ +K C+S PC NG +C+ Y C C G G +C Sbjct: 2779 DLSGFAHALSGELSAVVDK---CTSFPCQNGGKCTPTDSDYYCTCTSGFNGTNC 2829 Score = 39.5 bits (88), Expect = 0.038 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Query: 1499 NRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELG 1555 N +RE + C S C L C + C TCTC G G C V+ CE Sbjct: 4128 NAYKIRERI---CTSVDKCALDPCKNGATCHNGPRDFTCTCVNGFTGKDCSQDVNECEST 4184 Query: 1556 PCGA-ARCVPDQTPKGYSCACEPGY 1579 PC C+ +SC C+ G+ Sbjct: 4185 PCNENQNCI--NAFGSFSCVCKDGF 4207 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + PC NG C ++ Y C C +G GK+C Sbjct: 1871 CLNKPCLNGGSCFNMDGEYRCKCAKGFCGKNC 1902 Score = 37.5 bits (83), Expect = 0.15 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 4/37 (10%) Query: 1317 CSSAPCYNGAECSD---LWDTYICDCKEGHTGKDCAD 1350 C S PC GA C+ W+ Y C CK G+ G +CAD Sbjct: 339 CDSKPCGAGATCTHNLVAWN-YTCACKPGYYGDNCAD 374 Score = 36.3 bits (80), Expect = 0.35 Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAP-CYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+ C NG C D + +Y C+C ++GK C Sbjct: 3912 CTNNVNECNDPDLCKNGGVCKDSFGSYSCNCSSAYSGKHC 3951 Score = 35.9 bits (79), Expect = 0.47 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348 C+S PC G C+ L + Y C C G+TG+ C Sbjct: 601 CTSVPCGIGGNCTSLDNYGLYSCQCLAGYTGQHC 634 Score = 34.7 bits (76), Expect = 1.1 Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 9/65 (13%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 +++TC C G+TG NC + + + D +C++G C + C+ +AY+ Sbjct: 3897 SNYTCTCAPGYTGENCTNNVNECN-----DPDLCKNGGVC----KDSFGSYSCNCSSAYS 3947 Query: 1100 TAVCE 1104 CE Sbjct: 3948 GKHCE 3952 Score = 34.3 bits (75), Expect = 1.4 Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 6/75 (8%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSS-TCTCEAGRVGPQCV---SAC-ELGPCGAARCVPD 1565 C + C+L C C ++ CTC G C + C ++ PC C Sbjct: 2303 CLGFSKCVLKPCQNGGTCNPLDNTGYNCTCTPRYRGFNCTILRTVCTDVQPCDKGNCSMI 2362 Query: 1566 QTPKG-YSCACEPGY 1579 P G Y C C PGY Sbjct: 2363 SIPDGTYKCTCIPGY 2377 Score = 34.3 bits (75), Expect = 1.4 Identities = 20/64 (31%), Positives = 23/64 (35%), Gaps = 4/64 (6%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELG-PCGAARCVPDQTPKGYS 1572 C C KC + CTC +G G C + C G PC V T Y Sbjct: 2798 CTSFPCQNGGKCTPTDSDYYCTCTSGFNGTNCEKDIDECATGNPCTGVANVCHNTYGSYE 2857 Query: 1573 CACE 1576 C CE Sbjct: 2858 CMCE 2861 Score = 34.3 bits (75), Expect = 1.4 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC-ADSTGP 1354 C + + C S PC C + + ++ C CK+G C D T P Sbjct: 4174 CSQDVNECESTPCNENQNCINAFGSFSCVCKDGFKDVACQIDFTDP 4219 Score = 34.3 bits (75), Expect = 1.4 Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 1317 CSSAPCYNGAECSDLWDT-YICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNP 1368 C+ PC NG C + Y C C G TG +C G ++F+P Sbjct: 4402 CTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETGLGSTNSLSQLNQVAFDP 4454 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC-ADSTGP 1354 C C S+PC C + + ++ C CK+G +C D T P Sbjct: 4763 CSLDVDECKSSPCNKNQNCINSFGSFTCVCKDGLKADNCETDFTDP 4808 Score = 33.5 bits (73), Expect = 2.5 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 17/89 (19%) Query: 1262 LQIGGLPNIPSS-FQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA 1320 +++ LP+ PSS + +K V + K D+ +AD GT CSS Sbjct: 1267 IELRTLPSSPSSDYVIKETSMV------MLGRKVRDVRQAIADAGT---------PCSSN 1311 Query: 1321 PCYNGAECSD-LWDTYICDCKEGHTGKDC 1348 PC NG C++ Y C C +G+ C Sbjct: 1312 PCQNGGTCTEAAAGRYSCACPVRFSGEHC 1340 Score = 32.7 bits (71), Expect = 4.4 Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 1315 SRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348 S+C PC NG C+ L +T Y C C + G +C Sbjct: 2307 SKCVLKPCQNGGTCNPLDNTGYNCTCTPRYRGFNC 2341 Score = 32.3 bits (70), Expect = 5.8 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC--ADSTGPPWRFGGDG 1362 C+ PC NG C Y C C G TG +C A +G F DG Sbjct: 4991 CTKNPCLNGGTCIPSGPSVYTCTCTPGVTGANCETACKSGIDLVFAVDG 5039 >SB_786| Best HMM Match : EGF (HMM E-Value=0) Length = 1427 Score = 51.2 bits (117), Expect = 1e-05 Identities = 51/208 (24%), Positives = 74/208 (35%), Gaps = 31/208 (14%) Query: 1507 VRDGCQSRADCMLSICPP----YSKCV-TSWDSSTCTCEAGRVGPQCVSACELGPC-GAA 1560 +++G +S C+ +C P + +C+ + D C C+AG G C + C PC Sbjct: 152 IQEGTESY-QCVKKMCEPNPCQHGRCIEVNDDDYQCACDAGYTGKNCENFCSPNPCKNNG 210 Query: 1561 RCVPDQTPKGYSCACEPGYTLTTSGCIE-SGKEECPGGWWGGSACGPCACDVTRGYHPHC 1619 CV GY C C+ + ++ C G C D GY C Sbjct: 211 VCV--SRGVGYHCKCKRDFKGPHCEMVDMCDMNPCKN--------GRCVADEKAGYKCVC 260 Query: 1620 NKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 + +C EN+ C+P C G S + QC CR G G C+ Sbjct: 261 HSGFVGKNCDENY--------CVPNPCLNGGICKSVADKGY-QCKCREGYNGPHCERSPC 311 Query: 1680 AYAEVTPNSGCEVVYD----GCPRSFAG 1703 A C V Y CP + G Sbjct: 312 APNPCLNGGTCVVFYTVHLCKCPAHYRG 339 Score = 39.5 bits (88), Expect = 0.038 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 8/73 (10%) Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEG 1342 C++D +K + + +V N C E + C PC NG C + D Y C C+EG Sbjct: 248 CVADEKAGYKCVCHSGFVGKN-----CDE--NYCVPNPCLNGGICKSVADKGYQCKCREG 300 Query: 1343 HTGKDCADSTGPP 1355 + G C S P Sbjct: 301 YNGPHCERSPCAP 313 Score = 36.7 bits (81), Expect = 0.27 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 7/58 (12%) Query: 1301 VADNGTLAGCPE-------KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 VAD G C E +RS C+ PC NG C + ++C C + G C S Sbjct: 288 VADKGYQCKCREGYNGPHCERSPCAPNPCLNGGTCVVFYTVHLCKCPAHYRGNRCEAS 345 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/41 (34%), Positives = 19/41 (46%) Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 + C PC +G D Y C C G+TGK+C + P Sbjct: 163 KKMCEPNPCQHGRCIEVNDDDYQCACDAGYTGKNCENFCSP 203 >SB_57511| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 879 Score = 51.2 bits (117), Expect = 1e-05 Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 20/180 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C C C + S TCTC A GP C V+ C PC C T Y Sbjct: 575 ECATDPCDNGGTCANTDGSYTCTCTAAWTGPTCKQDVNECLNNPCVYGGTCT--NTVGDY 632 Query: 1572 SCACEPGYTLTTSGCIESGKEEC-------PGGWWGGSACGPCACDVTRGYHPHCNKENG 1624 SCAC G+ T C + +EC G + CAC V +C+++ Sbjct: 633 SCACVQGW--TGKDC-DQDVDECVANPCANQGTCYNNDGSYTCAC-VAGRTGLNCDQDVN 688 Query: 1625 KCHCK--ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682 +C +N T C C AA + +C+ +C P V G C Y+ Sbjct: 689 ECATDPCDNGGTCANTDGSYTCTCTAAWT-GPTCKQDVNECLNNPCVYGGTCTNTVGDYS 747 Score = 51.2 bits (117), Expect = 1e-05 Identities = 48/180 (26%), Positives = 68/180 (37%), Gaps = 19/180 (10%) Query: 1508 RDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563 +D Q +C+ + C C + S TC C AGR G C V+ C PC C Sbjct: 643 KDCDQDVDECVANPCANQGTCYNNDGSYTCACVAGRTGLNCDQDVNECATDPCDNGGTCA 702 Query: 1564 PDQTPKGYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCN 1620 T Y+C C +T T E C G + G +C +G+ C+ Sbjct: 703 --NTDGSYTCTCTAAWTGPTCKQDVNECLNNPCVYGGTCTNTVGDYSCACVQGWTGKDCD 760 Query: 1621 KENGKCHCKENHYKPEGTAECLPCQCY-AAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 ++ +C+ N +GT CY GS +C A +C V A D C N Sbjct: 761 QDINECY--NNPCANQGT-------CYNNDGSYTCACVAGWTGLNCDQDVNECATDPCDN 811 Score = 45.6 bits (103), Expect = 6e-04 Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 15/178 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELG-PC-GAARCVPDQTPKG 1570 +C L C CV + S C C A GP C V+ C PC C T Sbjct: 460 ECALKPCAYGGSCVNTMGSYQCLCTAQWQGPTCTTDVNECAASPPCVNGGSCT--NTAGD 517 Query: 1571 YSCACEPGYTLTTSG--CIESGKEEC--PGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 Y CAC G+ G E C G + CAC V +C+++ +C Sbjct: 518 YHCACVQGWMGKNCGQDVDECVANPCANQGTCYNNDGSYTCAC-VAGWTGLNCDQDVNEC 576 Query: 1627 HCK--ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682 +N T C C AA + +C+ +C P V G C Y+ Sbjct: 577 ATDPCDNGGTCANTDGSYTCTCTAAWT-GPTCKQDVNECLNNPCVYGGTCTNTVGDYS 633 Score = 41.1 bits (92), Expect = 0.012 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C + PC G C++ Y C C +G TGKDC Sbjct: 607 CKQDVNECLNNPCVYGGTCTNTVGDYSCACVQGWTGKDC 645 Score = 41.1 bits (92), Expect = 0.012 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C + PC G C++ Y C C +G TGKDC Sbjct: 721 CKQDVNECLNNPCVYGGTCTNTVGDYSCACVQGWTGKDC 759 Score = 37.5 bits (83), Expect = 0.15 Identities = 13/39 (33%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C++ PC NG C++ +Y C C TG C Sbjct: 569 CDQDVNECATDPCDNGGTCANTDGSYTCTCTAAWTGPTC 607 Score = 37.5 bits (83), Expect = 0.15 Identities = 13/39 (33%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C++ PC NG C++ +Y C C TG C Sbjct: 683 CDQDVNECATDPCDNGGTCANTDGSYTCTCTAAWTGPTC 721 Score = 37.1 bits (82), Expect = 0.20 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+ S PC NG C++ Y C C +G GK+C Sbjct: 492 CTTDVNECAASPPCVNGGSCTNTAGDYHCACVQGWMGKNC 531 Score = 35.5 bits (78), Expect = 0.62 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 10/64 (15%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 S+TC C G+TG+NC+ + + C D C +G C A +G C C+ AA+T Sbjct: 555 SYTCACVAGWTGLNCDQDVNE--CATDP----CDNGGTC-ANTDGSYTCT-CT--AAWTG 604 Query: 1101 AVCE 1104 C+ Sbjct: 605 PTCK 608 Score = 34.3 bits (75), Expect = 1.4 Identities = 12/39 (30%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C++ PC N C++ +Y C C TG C Sbjct: 797 CDQDVNECATDPCDNRGTCANTDGSYTCTCTAAWTGPTC 835 Score = 33.9 bits (74), Expect = 1.9 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C + PC N C + +Y C C G TG +C Sbjct: 645 CDQDVDECVANPCANQGTCYNNDGSYTCACVAGRTGLNC 683 Score = 33.9 bits (74), Expect = 1.9 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 10/64 (15%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 S+TC C G TG+NC+ + + C D C +G C A +G C C+ AA+T Sbjct: 669 SYTCACVAGRTGLNCDQDVNE--CATDP----CDNGGTC-ANTDGSYTCT-CT--AAWTG 718 Query: 1101 AVCE 1104 C+ Sbjct: 719 PTCK 722 Score = 33.5 bits (73), Expect = 2.5 Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C + PC N C + +Y C C G TG +C Sbjct: 759 CDQDINECYNNPCANQGTCYNNDGSYTCACVAGWTGLNC 797 Score = 33.5 bits (73), Expect = 2.5 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 3/45 (6%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC 1557 +C C C + S TCTC A GP C V+ C PC Sbjct: 803 ECATDPCDNRGTCANTDGSYTCTCTAAWTGPTCKQDVNECLNNPC 847 Score = 32.7 bits (71), Expect = 4.4 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C + PC N C + +Y C C G TG +C Sbjct: 531 CGQDVDECVANPCANQGTCYNNDGSYTCACVAGWTGLNC 569 Score = 32.3 bits (70), Expect = 5.8 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 10/64 (15%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 S+TC C G+TG+NC+ + + C D C + C A +G C C+ AA+T Sbjct: 783 SYTCACVAGWTGLNCDQDVNE--CATDP----CDNRGTC-ANTDGSYTCT-CT--AAWTG 832 Query: 1101 AVCE 1104 C+ Sbjct: 833 PTCK 836 >SB_45521| Best HMM Match : F5_F8_type_C (HMM E-Value=8.6e-23) Length = 247 Score = 50.4 bits (115), Expect = 2e-05 Identities = 19/43 (44%), Positives = 25/43 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C + + C S PC NGA C+D + Y C CK G+TG +C T Sbjct: 36 CQQDINECQSNPCLNGATCTDHVNRYTCSCKLGYTGIECQQET 78 Score = 46.0 bits (104), Expect = 4e-04 Identities = 17/34 (50%), Positives = 22/34 (64%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C S PC NGA C+D + Y C CK G+TG +C Sbjct: 3 NECQSNPCLNGATCTDHVNGYTCSCKLGYTGIEC 36 Score = 41.9 bits (94), Expect = 0.007 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TC+C+ G G +C ++ C+ PC D + Y+ Sbjct: 4 ECQSNPCLNGATCTDHVNGYTCSCKLGYTGIECQQDINECQSNPCLNGATCTDHVNR-YT 62 Query: 1573 CACEPGYT 1580 C+C+ GYT Sbjct: 63 CSCKLGYT 70 Score = 33.5 bits (73), Expect = 2.5 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V +TC C G+TG+ C+ +A+ + D +C SQ + + I+ C ++Y Sbjct: 58 VNRYTCSCKLGYTGIECQQETEEATAKGDLVLLVC---SQALGVQYRSIIPDACMTGSSY 114 Query: 1099 TTAVCELR 1106 ELR Sbjct: 115 YDNGYELR 122 >SB_18560| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1937 Score = 50.4 bits (115), Expect = 2e-05 Identities = 55/193 (28%), Positives = 68/193 (35%), Gaps = 28/193 (14%) Query: 1513 SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG--PQC--VSACELG-PCGAARCVPDQT 1567 S C +C +++C T C CE G G C ++ CE C + V T Sbjct: 835 SSVACGGKVCHTHAECFTYQGQKQCVCERGYQGNGEDCKDINECEQNHECDPLKAVCTNT 894 Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC---GPCACDVTRGYHPHCNKENG 1624 YSC C PGY G G+ P GG C G C D G C G Sbjct: 895 EGSYSCTCRPGY----GG---DGRTCTPISSCGGEVCHQFGECVTDDDTG-RKRCQCRVG 946 Query: 1625 KCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRA--C---DAC 1677 + N EC+P GS NS C G +C CR G + C D C Sbjct: 947 ---FRGNGVDCYDMDECIPL-LRTCGS-NSLCRNTLGGYECVCRRGFTKKEGNCINIDEC 1001 Query: 1678 ANAYAEVTPNSGC 1690 PN+ C Sbjct: 1002 EPGRNRCDPNADC 1014 Score = 39.9 bits (89), Expect = 0.029 Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 16/115 (13%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSS-----TCTCEAGRVGPQCVSA----CELGPCGA-A 1560 C+S C +C +CV +S TC C+ G G + C GPC A Sbjct: 1320 CKSDGTCEGKVCDFNGECVAKNNSDGETERTCRCKEGFEGDGIICTDQDECLKGPCPQNA 1379 Query: 1561 RCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615 +CV + Y C C PGY C ++ C GGS C+ +G+ Sbjct: 1380 KCVNNFG--SYLCICNPGYKKVNGKC----EKLCIRCMNGGSCVENNGCECPKGF 1428 Score = 39.1 bits (87), Expect = 0.050 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 16/116 (13%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDS--STCTCEAG--RVGPQCVSACELGP----CGAARC 1562 C + C +C + +CVT D+ C C G G C E P CG + Sbjct: 913 CTPISSCGGEVCHQFGECVTDDDTGRKRCQCRVGFRGNGVDCYDMDECIPLLRTCG-SNS 971 Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCI-----ESGKEECPGGWWGGSACG--PCACDV 1611 + T GY C C G+T CI E G+ C + G CAC V Sbjct: 972 LCRNTLGGYECVCRRGFTKKEGNCINIDECEPGRNRCDPNADCRNTVGSFQCACQV 1027 Score = 39.1 bits (87), Expect = 0.050 Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 30/165 (18%) Query: 1511 CQSRADCML--SICPPYSKCVTSWDSSTCTCEAGRV--GPQCVS--ACELGPCG-AARCV 1563 C+ +C L + C ++CV S C C G V G C S CE C CV Sbjct: 1279 CRDIDECALGHANCHRKAECVNQLGSFVCRCVIGYVGNGVDCKSDGTCEGKVCDFNGECV 1338 Query: 1564 PDQTPKG---YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620 G +C C+ G+ G I + ++EC GPC + C Sbjct: 1339 AKNNSDGETERTCRCKEGF--EGDGIICTDQDEC--------LKGPCP------QNAKCV 1382 Query: 1621 KENGK--CHCKENHYKPEGTAECLPCQCYAAGS--ENSSCEAATG 1661 G C C + K G E L +C GS EN+ CE G Sbjct: 1383 NNFGSYLCICNPGYKKVNGKCEKLCIRCMNGGSCVENNGCECPKG 1427 Score = 38.7 bits (86), Expect = 0.066 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 6/67 (8%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAG--RVGPQCVSACELGPCGAARCVPD--- 1565 C + +C+ CP +KCV ++ S C C G +V +C C + CV + Sbjct: 1364 CTDQDECLKGPCPQNAKCVNNFGSYLCICNPGYKKVNGKCEKLC-IRCMNGGSCVENNGC 1422 Query: 1566 QTPKGYS 1572 + PKG+S Sbjct: 1423 ECPKGFS 1429 Score = 33.9 bits (74), Expect = 1.9 Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 10/82 (12%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP---QCVSA--CELGP--CGA-ARCVPDQTPKGYSC 1573 C C+T C C G G C A C L C A A C+ T Y C Sbjct: 672 CHSLGVCITFQGRKECRCNYGYRGDGVSYCEDADECTLNRYRCDANAECI--NTVGSYRC 729 Query: 1574 ACEPGYTLTTSGCIESGKEECP 1595 C+ GYT C E+ + CP Sbjct: 730 KCKTGYTGDGKTCTEAEEFYCP 751 Score = 33.9 bits (74), Expect = 1.9 Identities = 43/173 (24%), Positives = 56/173 (32%), Gaps = 34/173 (19%) Query: 1519 LSICPPYSKCVTSWDSSTCTCEAGRVGPQ--CVSACELGPCGA------ARCVPDQTPKG 1570 L C P + C+ + S C C++G G C CG A C Q K Sbjct: 799 LDRCDPNADCIDTVGSYRCACKSGYTGDGSICTKVPSSVACGGKVCHTHAECFTYQGQK- 857 Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP--CACDVTRGYHPHCNKENGKCHC 1628 C CE GY C + EC C P C T G + C C Sbjct: 858 -QCVCERGYQGNGEDCKDI--NECE----QNHECDPLKAVCTNTEGSY--------SCTC 902 Query: 1629 KENHYKPEGTAECLPCQ------CYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 + Y +G C P C+ G + + +C CR G G D Sbjct: 903 RPG-YGGDGRT-CTPISSCGGEVCHQFGECVTDDDTGRKRCQCRVGFRGNGVD 953 Score = 32.7 bits (71), Expect = 4.4 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 9/78 (11%) Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGRVGP--QCVSACEL---GPCGA-ARC 1562 C+ +C L+ C ++C+ + S C C+ G G C A E C A+C Sbjct: 701 CEDADECTLNRYRCDANAECINTVGSYRCKCKTGYTGDGKTCTEAEEFYCPQKCHPNAKC 760 Query: 1563 VPDQTPKGYSCACEPGYT 1580 V G C C PGYT Sbjct: 761 VR-LAVGGQVCVCLPGYT 777 >SB_34444| Best HMM Match : Cadherin (HMM E-Value=0.0043) Length = 205 Score = 50.4 bits (115), Expect = 2e-05 Identities = 24/70 (34%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQ 242 N+ + Y+I+ GNT F +D+++G++ LV L+ E++ SY L + + DG R+ T Sbjct: 26 NANVSYSIVSGNTGAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGMPVIRTQVPTS 85 Query: 243 LLINIRDVND 252 L I + D D Sbjct: 86 LRIKLIDTVD 95 Score = 33.9 bits (74), Expect = 1.9 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 8/80 (10%) Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GV 558 +NA ++YS+ S N A H ++ TG I L+RE ++ Y LTV + DG V Sbjct: 25 MNANVSYSIVS--GNTGAAFH-----VDNVTGEIKLVSKLEREKITSYTLTVGSADGMPV 77 Query: 559 PSLSDTTDVEISVVDVNDNE 578 T + I ++D D E Sbjct: 78 IRTQVPTSLRIKLIDTVDLE 97 >SB_26697| Best HMM Match : EGF (HMM E-Value=7.5e-34) Length = 684 Score = 50.4 bits (115), Expect = 2e-05 Identities = 19/43 (44%), Positives = 25/43 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C + + C S PC NGA C+D + Y C CK G+TG +C T Sbjct: 473 CQQDINECQSNPCLNGATCTDHVNRYTCSCKLGYTGIECQQET 515 Score = 47.2 bits (107), Expect = 2e-04 Identities = 18/39 (46%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC NGA C+D + Y C CK G+TG +C Sbjct: 435 CETDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIEC 473 Score = 41.9 bits (94), Expect = 0.007 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TC+C+ G G +C ++ C+ PC D + Y+ Sbjct: 441 ECQSNPCLNGATCTDHVNGYTCSCKLGYTGIECQQDINECQSNPCLNGATCTDHVNR-YT 499 Query: 1573 CACEPGYT 1580 C+C+ GYT Sbjct: 500 CSCKLGYT 507 Score = 40.7 bits (91), Expect = 0.016 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 1315 SRCSSAPCYNGAECSDLW--DTYICDCKEGHTGKDC 1348 S C S PC +G+ C + DTY C C +G+TG+ C Sbjct: 400 SPCQSDPCLHGSRCLATYTDDTYTCACLQGYTGRHC 435 Score = 35.1 bits (77), Expect = 0.82 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 8/94 (8%) Query: 1037 YPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-REGGILCQ-- 1090 Y ++TC C +G+TG +CET + + +G+ C +G C + GI CQ Sbjct: 417 YTDDTYTCACLQGYTGRHCETDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIECQQD 476 Query: 1091 --GCSIDAAYTTAVCELRARSFPVSSFLTFPGLK 1122 C + A C + S L + G++ Sbjct: 477 INECQSNPCLNGATCTDHVNRYTCSCKLGYTGIE 510 Score = 34.7 bits (76), Expect = 1.1 Identities = 34/128 (26%), Positives = 46/128 (35%), Gaps = 17/128 (13%) Query: 1549 VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGP 1606 +S C+ PC +RC+ T Y+CAC GY T C E+ EC G+ C Sbjct: 399 LSPCQSDPCLHGSRCLATYTDDTYTCACLQGY--TGRHC-ETDINECQSNPCLNGATC-- 453 Query: 1607 CACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCR 1666 D GY C C+++ EC C + T C C+ Sbjct: 454 --TDHVNGYTCSCKLGYTGIECQQD------INECQSNPCLNGATCTDHVNRYT--CSCK 503 Query: 1667 PGVIGRAC 1674 G G C Sbjct: 504 LGYTGIEC 511 Score = 31.9 bits (69), Expect = 7.6 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V +TC C G+TG+ C+ +A+ + D +C SQ + + I+ C ++Y Sbjct: 495 VNRYTCSCKLGYTGIECQQETEEATAKGDLVLLVC---SQALGVQYRSIIPDACMTGSSY 551 >SB_4999| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 1054 Score = 50.4 bits (115), Expect = 2e-05 Identities = 49/171 (28%), Positives = 66/171 (38%), Gaps = 18/171 (10%) Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELG--PCGA-AR 1561 C +C L+I CP CV + S TC C+ G V C + C LG C A A Sbjct: 420 CDDIDECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVATCPASAD 479 Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNK 1621 CV + Y+C C+ GYTL + C EC + C G C Sbjct: 480 CVNNDG--SYTCRCKRGYTLKNNEC--EDVNECLDLFLNTCLFKGLDCINLPG-SLQCKC 534 Query: 1622 ENGKCHCKENHYKPEGTAECLPC--QCYAAGSENSSCEAATGQ--CHCRPG 1668 G+ ++ Y G + C Y +NS C+ G C C+PG Sbjct: 535 PAGQKWDPDSFYGTGGCVDLNECVETPYVCSGDNSICQNTEGSFTCSCKPG 585 Score = 48.4 bits (110), Expect = 8e-05 Identities = 48/199 (24%), Positives = 72/199 (36%), Gaps = 23/199 (11%) Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGRV--GPQC--VSACELGP--CGAARC 1562 C +C L + CP + CV + S TC C+ G C V+ C P C Sbjct: 99 CDDIDECALGVATCPASADCVNNDGSYTCRCKRGYTLNNNTCTDVNECTEIPYVCSGENS 158 Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKE 1622 + + T + C+C+ GYT S + + P + R +C Sbjct: 159 ICENTDGSFKCSCKSGYTPKFSEAV----GDAPANLTSCDGKTAVHSKLVRNVIRYCVNN 214 Query: 1623 NGK--CHCKENHYKPEGTAECL-PCQCYAAGSENSS-CEAATGQ--CHCRPG--VIGRAC 1674 +G C CK + T E + C A S+ C G C C+PG ++ C Sbjct: 215 DGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCVNNDGSYTCRCKPGYTLVNNTC 274 Query: 1675 ---DACANAYAEVTPNSGC 1690 D CA A ++ C Sbjct: 275 KDIDECALGVATCPASADC 293 Score = 44.4 bits (100), Expect = 0.001 Identities = 41/163 (25%), Positives = 60/163 (36%), Gaps = 16/163 (9%) Query: 1549 VSACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606 V+ C P C + + T ++C+C+ GYT S + + P Sbjct: 49 VNECTETPYVCSGNNSICENTDGSFNCSCKSGYTPKFSEAV----GDAPANLTSCDDIDE 104 Query: 1607 CACDV-TRGYHPHCNKENGK--CHCKENHYKPEGTA----ECLPCQCYAAGSENSSCEAA 1659 CA V T C +G C CK + T EC Y ENS CE Sbjct: 105 CALGVATCPASADCVNNDGSYTCRCKRGYTLNNNTCTDVNECTEIP-YVCSGENSICENT 163 Query: 1660 TG--QCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRS 1700 G +C C+ G + +A +A A +T G V+ R+ Sbjct: 164 DGSFKCSCKSGYTPKFSEAVGDAPANLTSCDGKTAVHSKLVRN 206 Score = 36.3 bits (80), Expect = 0.35 Identities = 13/31 (41%), Positives = 20/31 (64%), Gaps = 2/31 (6%) Query: 1320 APCYNGAECSDLWDTYICDCKEGHT--GKDC 1348 +PC+ A C++ +Y+C C G+T GKDC Sbjct: 615 SPCHENAACTNTKGSYLCRCNSGYTGDGKDC 645 Score = 35.5 bits (78), Expect = 0.62 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 17/110 (15%) Query: 1514 RADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG--PCGAAR-CVPDQTPKG 1570 + C P +SK V ++ +C+ + C+L C A R CV + Sbjct: 395 KCSCKPGYTPKFSKAVGDAPANLTSCDD-------IDECKLNISTCPANRYCVNNDG--S 445 Query: 1571 YSCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCACDVTRGY 1615 Y+C C+PGYTL + C + G CP + G C RGY Sbjct: 446 YTCKCKPGYTLVNNTCEDIDECALGVATCPASADCVNNDGSYTCRCKRGY 495 Score = 34.7 bits (76), Expect = 1.1 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 13/102 (12%) Query: 1502 TVRENVRDGCQSRADCMLSICPPYS-KCVTSWDSSTCTCEAGRV-GPQ-------CV--S 1550 T++ N + D L+ C C+ S C C AG+ P CV + Sbjct: 496 TLKNNECEDVNECLDLFLNTCLFKGLDCINLPGSLQCKCPAGQKWDPDSFYGTGGCVDLN 555 Query: 1551 ACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESG 1590 C P C + T ++C+C+PGYT T SG + G Sbjct: 556 ECVETPYVCSGDNSICQNTEGSFTCSCKPGYTPTFSGSVSDG 597 Score = 31.9 bits (69), Expect = 7.6 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 23/133 (17%) Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 Y+C C+PGYTL + C + +EC G + C P + D N + C CK Sbjct: 218 YTCKCKPGYTLVNNTCEDI--DECA---LGVANC-PASADCVN------NDGSYTCRCKP 265 Query: 1631 NHYKPEGTAECLPCQC---YAAGSENSSCEAATGQ--CHCRPG--VIGRACDA---CANA 1680 + T + + +C A ++ C G C C+ G ++ + C A + Sbjct: 266 GYTLVNNTCKDID-ECALGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCTARWSVISN 324 Query: 1681 YAEVTPNSGCEVV 1693 + ++T N E++ Sbjct: 325 FLQITNNERYELL 337 >SB_46333| Best HMM Match : EGF (HMM E-Value=1.10001e-40) Length = 580 Score = 50.0 bits (114), Expect = 3e-05 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 7/77 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCV 1563 C+++ C S C + C+ D+S CTC AG G C V C+ PC A C Sbjct: 115 CETQVKPCDSSPCKNNATCINDKDNSGYNCTCSAGFTGSDCETQVKPCDSSPCKNNATCT 174 Query: 1564 PDQTPKGYSCACEPGYT 1580 + GY+C C G+T Sbjct: 175 NKEDNSGYNCTCSAGFT 191 Score = 48.8 bits (111), Expect = 6e-05 Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 18/165 (10%) Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570 C S C + C+ D+S CTC AG G C V C+ PC A C Sbjct: 42 CDSSPCKNNATCINKEDNSGYNCTCSAGFTGSDCETQVKPCDTIPCKNNATCTNKDDNSS 101 Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV-TRGYHPHCNKENGKCHCK 1629 Y+C C G+ T S C E+ + C +A C D GY+ C+ C Sbjct: 102 YNCTCSTGF--TGSDC-ETQVKPCDSSPCKNNA--TCINDKDNSGYNCTCSAGFTGSDC- 155 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 E KP + PC+ A + + + C C G G C Sbjct: 156 ETQVKP---CDSSPCKNNATCTNKE--DNSGYNCTCSAGFTGNDC 195 Score = 48.8 bits (111), Expect = 6e-05 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 7/77 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSST--CTCEAGRVGPQC---VSACELGPC-GAARCV 1563 C+++ C C + C D+S+ CTC G G C V C+ PC A C+ Sbjct: 75 CETQVKPCDTIPCKNNATCTNKDDNSSYNCTCSTGFTGSDCETQVKPCDSSPCKNNATCI 134 Query: 1564 PDQTPKGYSCACEPGYT 1580 D+ GY+C C G+T Sbjct: 135 NDKDNSGYNCTCSAGFT 151 Score = 41.9 bits (94), Expect = 0.007 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 6/85 (7%) Query: 1275 QVKNKDFVGCISDFYIDHKFIDLNSY--VADNG-TLAGCPEKRSRCSSAPCYNGAECSDL 1331 QVK D + C ++ +K D +SY G T + C + C S+PC N A C + Sbjct: 78 QVKPCDTIPCKNNATCTNKD-DNSSYNCTCSTGFTGSDCETQVKPCDSSPCKNNATCIND 136 Query: 1332 WDT--YICDCKEGHTGKDCADSTGP 1354 D Y C C G TG DC P Sbjct: 137 KDNSGYNCTCSAGFTGSDCETQVKP 161 Score = 40.7 bits (91), Expect = 0.016 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348 T + C + C S+PC N A C++ D Y C C G TG DC Sbjct: 151 TGSDCETQVKPCDSSPCKNNATCTNKEDNSGYNCTCSAGFTGNDC 195 Score = 40.3 bits (90), Expect = 0.022 Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 3/55 (5%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354 + +G A +S C S+PC N A C + D Y C C G TG DC P Sbjct: 28 SSSGACANATRVKS-CDSSPCKNNATCINKEDNSGYNCTCSAGFTGSDCETQVKP 81 Score = 39.9 bits (89), Expect = 0.029 Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354 T + C + C + PC N A C++ D +Y C C G TG DC P Sbjct: 71 TGSDCETQVKPCDTIPCKNNATCTNKDDNSSYNCTCSTGFTGSDCETQVKP 121 Score = 38.7 bits (86), Expect = 0.066 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 8/69 (11%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 +S+ C C GFTG +CET + D S C++ + C+ ++ C+ A +T Sbjct: 100 SSYNCTCSTGFTGSDCETQVKPC------DSSPCKNNATCINDKDNS--GYNCTCSAGFT 151 Query: 1100 TAVCELRAR 1108 + CE + + Sbjct: 152 GSDCETQVK 160 Score = 36.7 bits (81), Expect = 0.27 Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 6/50 (12%) Query: 1537 CTCEAGRVGPQCVSA-----CELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 C C+ G C +A C+ PC A C+ + GY+C C G+T Sbjct: 22 CECQKGSSSGACANATRVKSCDSSPCKNNATCINKEDNSGYNCTCSAGFT 71 Score = 31.9 bits (69), Expect = 7.6 Identities = 16/69 (23%), Positives = 30/69 (43%), Gaps = 8/69 (11%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 + + C C GFTG +CET + D C++ + C + + C+ +T Sbjct: 60 SGYNCTCSAGFTGSDCETQVKPC------DTIPCKNNATCTNKDDNS--SYNCTCSTGFT 111 Query: 1100 TAVCELRAR 1108 + CE + + Sbjct: 112 GSDCETQVK 120 >SB_49700| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 7645 Score = 50.0 bits (114), Expect = 3e-05 Identities = 41/138 (29%), Positives = 56/138 (40%), Gaps = 18/138 (13%) Query: 938 DDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYL-HRTTLA-RLATVQVL 995 D T VT +LN R V + D + T +R TL TV +L Sbjct: 6871 DYTQVTDKVLNFDVEETRIVVSVPIVDDALVEPTETFYATLTTADNRVTLGPENTTVYIL 6930 Query: 996 PFDDNICVHEPCLN---------FEECLTVLKFGNASGFVNSDSVLFRP-------IYPV 1039 D N C EPC N + +C V F + +N + + P + + Sbjct: 6931 DNDVNECDSEPCQNGGSCTDMGNYYQCACVPGFSGVNCEINVNECMSAPCKNGATCVDGI 6990 Query: 1040 TSFTCQCPEGFTGVNCET 1057 S+TCQC G+TGVNCET Sbjct: 6991 NSYTCQCAVGYTGVNCET 7008 Score = 49.6 bits (113), Expect = 4e-05 Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 7/70 (10%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC---ADSTGP-PWRFGG---DG 1362 C + C SAPC NGA C D ++Y C C G+TG +C D P P ++GG DG Sbjct: 6968 CEINVNECMSAPCKNGATCVDGINSYTCQCAVGYTGVNCETNPDDCHPNPCQYGGTCVDG 7027 Query: 1363 MLSFNPLLRP 1372 + F L P Sbjct: 7028 LDDFTCLCVP 7037 Score = 48.0 bits (109), Expect = 1e-04 Identities = 47/184 (25%), Positives = 69/184 (37%), Gaps = 27/184 (14%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C ++C+ + C C G G +C + C PC RC+ DQ Y Sbjct: 7126 ECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGGRCI-DQV-NDY 7183 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGP------CACDVTRGY------HPH 1618 C C PG+ C E+ ++C G+ C C C + GY H Sbjct: 7184 ECQCLPGFV--GDNC-ETNVDDCADNPCLNGATCIDGVNDYYCVCAI--GYYSKNCEHIS 7238 Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678 CN+ + C + + E T+ C C C G+ S C C G G C+ Sbjct: 7239 CNRFSVLLIC--DLFLSE-TSTCTDCTCENGGTCGVSSVYGHWFCVCPKGFKGERCEIAD 7295 Query: 1679 NAYA 1682 N A Sbjct: 7296 NGCA 7299 Score = 46.0 bits (104), Expect = 4e-04 Identities = 41/175 (23%), Positives = 58/175 (33%), Gaps = 12/175 (6%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS---ACELGPCG-AARCVPDQTPKGY 1571 +CM + C + CV +S TC C G G C + C PC CV + Sbjct: 6974 ECMSAPCKNGATCVDGINSYTCQCAVGYTGVNCETNPDDCHPNPCQYGGTCVDGL--DDF 7031 Query: 1572 SCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHC 1628 +C C PG T + E C C GY HC + C Sbjct: 7032 TCLCVPGTTGKICHININECNSNPCRNNGTCVDGINGFTCRCLEGYIGAHCEVDVNYCDS 7091 Query: 1629 KE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 + N+ + C C A G +C+ +C P + G C N + Sbjct: 7092 EPCMNNATCVDEQDGFTCIC-APGYTGPTCDGDIDECAFNPCLNGAECINLENGF 7145 Score = 42.7 bits (96), Expect = 0.004 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C C+ PC NGAEC +L + + C C G+TGK C D T P GG Sbjct: 7120 CDGDIDECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGG 7174 Score = 41.1 bits (92), Expect = 0.012 Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C S PC NG C+D+ + Y C C G +G +C Sbjct: 6935 NECDSEPCQNGGSCTDMGNYYQCACVPGFSGVNC 6968 Score = 41.1 bits (92), Expect = 0.012 Identities = 17/41 (41%), Positives = 20/41 (48%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A C + C S PC N A C D D + C C G+TG C Sbjct: 7080 AHCEVDVNYCDSEPCMNNATCVDEQDGFTCICAPGYTGPTC 7120 Score = 40.7 bits (91), Expect = 0.016 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348 C + C++ PC NG C D Y C C+EG TGK+C Sbjct: 7291 CEIADNGCATKPCQNGGSCCQDPVKGYSCICREGFTGKNC 7330 Score = 39.5 bits (88), Expect = 0.038 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343 CI D D++ L +V DN C C+ PC NGA C D + Y C C G+ Sbjct: 7176 CI-DQVNDYECQCLPGFVGDN-----CETNVDDCADNPCLNGATCIDGVNDYYCVCAIGY 7229 Query: 1344 TGKDC 1348 K+C Sbjct: 7230 YSKNC 7234 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/32 (40%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ +PC NG C D + Y C C G G +C Sbjct: 7165 CTPSPCINGGRCIDQVNDYECQCLPGFVGDNC 7196 Score = 37.5 bits (83), Expect = 0.15 Identities = 44/172 (25%), Positives = 57/172 (33%), Gaps = 16/172 (9%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC S C +C+ + C C G VG C V C PC A C+ Y Sbjct: 7164 DCTPSPCINGGRCIDQVNDYECQCLPGFVGDNCETNVDDCADNPCLNGATCI--DGVNDY 7221 Query: 1572 SCACEPGYTLTTSGCIESGKEE----CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627 C C GY I + C S C C C+ + C Sbjct: 7222 YCVCAIGYYSKNCEHISCNRFSVLLICDLFLSETSTCTDCTCENGGTCGVSSVYGHWFCV 7281 Query: 1628 CKENHYKPEGTAECLPCQCYAAGSEN-SSC--EAATG-QCHCRPGVIGRACD 1675 C + +K E E C +N SC + G C CR G G+ C+ Sbjct: 7282 CPKG-FKGE-RCEIADNGCATKPCQNGGSCCQDPVKGYSCICREGFTGKNCE 7331 Score = 36.3 bits (80), Expect = 0.35 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 1297 LNSYV---ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 +NSY A T C C PC G C D D + C C G TGK C Sbjct: 6990 INSYTCQCAVGYTGVNCETNPDDCHPNPCQYGGTCVDGLDDFTCLCVPGTTGKIC 7044 Score = 35.9 bits (79), Expect = 0.47 Identities = 14/39 (35%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S PC N C D + + C C EG+ G C Sbjct: 7044 CHININECNSNPCRNNGTCVDGINGFTCRCLEGYIGAHC 7082 Score = 33.5 bits (73), Expect = 2.5 Identities = 18/66 (27%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + FTC+C EG+ G +CE + D C + + CV ++G C Y Sbjct: 7066 INGFTCRCLEGYIGAHCEVDVNYC------DSEPCMNNATCVDEQDGFT----CICAPGY 7115 Query: 1099 TTAVCE 1104 T C+ Sbjct: 7116 TGPTCD 7121 Score = 33.5 bits (73), Expect = 2.5 Identities = 12/19 (63%), Positives = 14/19 (73%) Query: 1038 PVTSFTCQCPEGFTGVNCE 1056 PV ++C C EGFTG NCE Sbjct: 7313 PVKGYSCICREGFTGKNCE 7331 Score = 32.7 bits (71), Expect = 4.4 Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 R I V + CQC GF G NCET + + +G+ C G Sbjct: 7175 RCIDQVNDYECQCLPGFVGDNCETNVDDCADNPCLNGATCIDG 7217 Score = 31.9 bits (69), Expect = 7.6 Identities = 15/51 (29%), Positives = 25/51 (49%) Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 ++ I + I+DD N PQ + S D +I ++ N V+ I D +G Sbjct: 694 TSKVIIIPILDDKKNEPQETFTVTVSSADSNIEISPNEVVITILDNDVSIG 744 Score = 31.9 bits (69), Expect = 7.6 Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 17/127 (13%) Query: 1549 VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPC 1607 V+ C+ PC D Y CAC PG+ + C E EC G+ C Sbjct: 6934 VNECDSEPCQNGGSCTDMG-NYYQCACVPGF--SGVNC-EINVNECMSAPCKNGATC--- 6986 Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667 D Y C +C+ N P+ +C P C G+ + T C C P Sbjct: 6987 -VDGINSYTCQCAVGYTGVNCETN---PD---DCHPNPCQYGGTCVDGLDDFT--CLCVP 7037 Query: 1668 GVIGRAC 1674 G G+ C Sbjct: 7038 GTTGKIC 7044 >SB_37565| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 286 Score = 50.0 bits (114), Expect = 3e-05 Identities = 16/34 (47%), Positives = 25/34 (73%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 ++C S+PC NG C+D + YIC C+ G+TG++C Sbjct: 3 NKCESSPCKNGGNCTDQVNNYICTCQPGYTGRNC 36 Score = 49.6 bits (113), Expect = 4e-05 Identities = 17/39 (43%), Positives = 25/39 (64%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CP + + C S PC NG +D ++ Y C C+ G+TGK+C Sbjct: 89 CPIEHNDCESCPCKNGGSYTDRFNDYTCKCQPGYTGKNC 127 Score = 37.1 bits (82), Expect = 0.20 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 1/60 (1%) Query: 1289 YIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 Y D +F D T C C+ PC N +C D + Y C C+ G +G++C Sbjct: 107 YTD-RFNDYTCKCQPGYTGKNCEIDIDECAGNPCKNKGKCIDHVNNYTCRCQAGVSGRNC 165 Score = 33.9 bits (74), Expect = 1.9 Identities = 34/132 (25%), Positives = 44/132 (33%), Gaps = 10/132 (7%) Query: 1549 VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA 1608 ++ CE PC DQ Y C C+PGY T C + E G Sbjct: 2 INKCESSPCKNGGNCTDQV-NNYICTCQPGY--TGRNCEKDIPEMLKQGELNVCDRRDST 58 Query: 1609 CDVTRGYHPHCNKENGKCHC-----KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663 T + K K C + N P +C C C GS T C Sbjct: 59 VYGTAYRTVYQLKYETKIFCCPGWKQFNISCPIEHNDCESCPCKNGGSYTDRFNDYT--C 116 Query: 1664 HCRPGVIGRACD 1675 C+PG G+ C+ Sbjct: 117 KCQPGYTGKNCE 128 Score = 33.1 bits (72), Expect = 3.3 Identities = 18/67 (26%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC C ++ TC C+ G G C + C PC +C+ D Y Sbjct: 95 DCESCPCKNGGSYTDRFNDYTCKCQPGYTGKNCEIDIDECAGNPCKNKGKCI-DHV-NNY 152 Query: 1572 SCACEPG 1578 +C C+ G Sbjct: 153 TCRCQAG 159 Score = 32.7 bits (71), Expect = 4.4 Identities = 42/176 (23%), Positives = 53/176 (30%), Gaps = 13/176 (7%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSAC-ELGPCGAARCVPDQTPKGYSCAC 1575 C S C C ++ CTC+ G G C E+ G + Y A Sbjct: 5 CESSPCKNGGNCTDQVNNYICTCQPGYTGRNCEKDIPEMLKQGELNVCDRRDSTVYGTAY 64 Query: 1576 EPGYTL---TTSGCIESGKE---ECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 Y L T C K+ CP + C C C Y N KC Sbjct: 65 RTVYQLKYETKIFCCPGWKQFNISCP---IEHNDCESCPCKNGGSYTDRFNDYTCKCQPG 121 Query: 1630 ENHYKPE-GTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV 1684 E EC C G T C C+ GV GR C+ + A + Sbjct: 122 YTGKNCEIDIDECAGNPCKNKGKCIDHVNNYT--CRCQAGVSGRNCEKVPTSCASI 175 Score = 32.7 bits (71), Expect = 4.4 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 16/79 (20%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV-------ARREGGILCQGCSI 1094 +TC+C G+TG NCE + + + G+ C++ +C+ R + G+ + C Sbjct: 114 YTCKCQPGYTGKNCEIDIDECA------GNPCKNKGKCIDHVNNYTCRCQAGVSGRNCE- 166 Query: 1095 DAAYTTAVCELRARSFPVS 1113 T+ +RA F +S Sbjct: 167 --KVPTSCASIRALGFTIS 183 >SB_34555| Best HMM Match : EGF (HMM E-Value=7.00649e-45) Length = 979 Score = 50.0 bits (114), Expect = 3e-05 Identities = 43/168 (25%), Positives = 58/168 (34%), Gaps = 22/168 (13%) Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570 C S C C D++ TCTC + G +C V C+ PC C G Sbjct: 213 CDSSPCKNGGSCTNKPDNTGYTCTCPSEYTGTECETQVQPCDSSPCKNGGACANKADNSG 272 Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 Y+C C GYT IE + P PC D + P N C C Sbjct: 273 YTCDCASGYT-----GIECESQVTP------CESNPCKNDGSCANKP--NNTGYTCTCTS 319 Query: 1631 NHYKPEGTAECLPCQ---CYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 + E + PC C G+ + + + C C G G C+ Sbjct: 320 EYTGTECETQVQPCDSSPCKNGGACANKADNSGFTCACASGYTGIECE 367 Score = 44.8 bits (101), Expect = 0.001 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354 C + C S+PC NG C++ D Y CDC G+TG +C P Sbjct: 246 CETQVQPCDSSPCKNGGACANKADNSGYTCDCASGYTGIECESQVTP 292 Score = 42.7 bits (96), Expect = 0.004 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCV 1563 C+S+ C + C C +++ TCTC + G +C V C+ PC C Sbjct: 286 CESQVTPCESNPCKNDGSCANKPNNTGYTCTCTSEYTGTECETQVQPCDSSPCKNGGACA 345 Query: 1564 PDQTPKGYSCACEPGYT 1580 G++CAC GYT Sbjct: 346 NKADNSGFTCACASGYT 362 Score = 40.7 bits (91), Expect = 0.016 Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 1313 KRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354 K RC S+PC NG C++ D Y C C +TG +C P Sbjct: 209 KVQRCDSSPCKNGGSCTNKPDNTGYTCTCPSEYTGTECETQVQP 252 Score = 39.1 bits (87), Expect = 0.050 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 10/66 (15%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARRE-GGILCQGCSIDAAY 1098 T +TC CP +TG CET + D S C++G C + + G C C+ + Y Sbjct: 231 TGYTCTCPSEYTGTECETQVQPC------DSSPCKNGGACANKADNSGYTCD-CA--SGY 281 Query: 1099 TTAVCE 1104 T CE Sbjct: 282 TGIECE 287 Score = 38.3 bits (85), Expect = 0.088 Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348 C + C S+PC NG C++ D + C C G+TG +C Sbjct: 326 CETQVQPCDSSPCKNGGACANKADNSGFTCACASGYTGIEC 366 Score = 36.3 bits (80), Expect = 0.35 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 8/65 (12%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 T +TC C +TG CET + D S C++G C + + C+ + YT Sbjct: 311 TGYTCTCTSEYTGTECETQVQPC------DSSPCKNGGACANKADNSGFT--CACASGYT 362 Query: 1100 TAVCE 1104 CE Sbjct: 363 GIECE 367 Score = 35.1 bits (77), Expect = 0.82 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 8/69 (11%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 + +TC C G+TG+ CE+ +T CE + C++ C + C+ + YT Sbjct: 271 SGYTCDCASGYTGIECESQVT--PCE----SNPCKNDGSCANKPNN--TGYTCTCTSEYT 322 Query: 1100 TAVCELRAR 1108 CE + + Sbjct: 323 GTECETQVQ 331 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 2/47 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354 C + + C S PC N C++ + Y C C +TG +C P Sbjct: 286 CESQVTPCESNPCKNDGSCANKPNNTGYTCTCTSEYTGTECETQVQP 332 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%) Query: 1318 SSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348 +S+PC NGA C++ D Y+C C TG C Sbjct: 778 NSSPCKNGATCTNSADNPGYMCTCSNVFTGSTC 810 >SB_6077| Best HMM Match : EGF (HMM E-Value=0) Length = 1165 Score = 50.0 bits (114), Expect = 3e-05 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC----ADSTGPPWRFGG 1360 C C+ APC +G+ C DL + Y C C +G+TGKDC + + P ++GG Sbjct: 402 CSVNIDDCADAPCQHGSTCIDLVNDYKCSCLQGYTGKDCHIDINECSSNPCQYGG 456 Score = 47.2 bits (107), Expect = 2e-04 Identities = 17/39 (43%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S+PC NGA C DL D + C C+ G G++C Sbjct: 250 CQVNIDECASSPCKNGATCEDLVDEFRCQCQPGFKGQNC 288 Score = 46.8 bits (106), Expect = 3e-04 Identities = 46/168 (27%), Positives = 56/168 (33%), Gaps = 14/168 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC + C Y C TC C G G C + CE PC A C D KGY Sbjct: 940 DCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL-KGY 998 Query: 1572 SCACEPGYTLTTSGCIESGKEEC--PGGWWGGSACGPCACDVTRGYHPHCNKENGKC--- 1626 SC+C G T + C G + C C + P C + C Sbjct: 999 SCSCPTGVTGRHCDVSICDSKPCRNNGSCVLTQSGYQCLC-ASSFTSPQCQRSIDDCEHA 1057 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 HC N + C C G CE +CH +P G C Sbjct: 1058 HCL-NGATCVDSDNAYKCSC-LEGYYGKHCE-LIDRCHSQPCQNGATC 1102 Score = 45.2 bits (102), Expect = 8e-04 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C+ + C S C+ ++ CTC G G C + C+ PC D Y Sbjct: 294 ECIGAACANGSTCIDLVNAYQCTCLPGFTGRHCDVDIDECQSNPCQHGSACMDGV-SSYQ 352 Query: 1573 CACEPGYT 1580 C C+PGYT Sbjct: 353 CICQPGYT 360 Score = 44.4 bits (100), Expect = 0.001 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 GTL C C +PC NGA C DL + + C C G G+ CA Sbjct: 589 GTL--CDVNVDECEDSPCANGASCEDLINDFRCHCPAGFQGRTCA 631 Score = 44.0 bits (99), Expect = 0.002 Identities = 15/39 (38%), Positives = 24/39 (61%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+++PC N A+C+D+ Y C C+ G+TG C Sbjct: 630 CAVDINECATSPCLNEAKCTDVVSGYRCTCRSGYTGTRC 668 Score = 44.0 bits (99), Expect = 0.002 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C C+++PC N A C+DL + + C C G+ G+ CA D T P + GG Sbjct: 820 CEANIDDCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGG 874 Score = 44.0 bits (99), Expect = 0.002 Identities = 48/189 (25%), Positives = 63/189 (33%), Gaps = 27/189 (14%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQT----PKGY 1571 DC C CV + TC C G G C + E+ CG+ C+ + T Sbjct: 864 DCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINC--SIEMDECGSYPCLNNGTCVDGRNRV 921 Query: 1572 SCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 +C C G+T E ++C P C D T +P E C Sbjct: 922 TCTCAVGFT---GQFCEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGET----CAT 974 Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSC--EAATG-QCHCRPGVIGRACDACANAYAEVTPN 1687 P E PCQ N++C + G C C GV GR CD N Sbjct: 975 ----PIDLCEAHPCQ------NNATCRMDPLKGYSCSCPTGVTGRHCDVSICDSKPCRNN 1024 Query: 1688 SGCEVVYDG 1696 C + G Sbjct: 1025 GSCVLTQSG 1033 Score = 43.2 bits (97), Expect = 0.003 Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC N A C DL + + C C +G TG+ C Sbjct: 136 CETNYNDCHSNPCQNNATCQDLINDFSCQCPQGITGQTC 174 Score = 42.7 bits (96), Expect = 0.004 Identities = 48/180 (26%), Positives = 62/180 (34%), Gaps = 29/180 (16%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPD 1565 C+S+ + C S C + C+ ++ TC C G G C V CE PC A C + Sbjct: 554 CESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLCDVNVDECEDSPCANGASC--E 611 Query: 1566 QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625 + C C G+ T C E + C DV GY C Sbjct: 612 DLINDFRCHCPAGFQGRT--CAVDINECATSPCLNEAKC----TDVVSGYRCTCRSGYTG 665 Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRAC----DACAN 1679 C+ + EC C G C T +C C PG G C D CAN Sbjct: 666 TRCERD------IDECSSSPCVNGG----LCVDYTNYFECLCHPGYGGDRCEINIDDCAN 715 Score = 42.7 bits (96), Expect = 0.004 Identities = 19/47 (40%), Positives = 22/47 (46%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A + T C C A C NGA C D + Y C C EG+ GK C Sbjct: 1039 ASSFTSPQCQRSIDDCEHAHCLNGATCVDSDNAYKCSCLEGYYGKHC 1085 Score = 42.3 bits (95), Expect = 0.005 Identities = 16/39 (41%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + CSS+PC NG C+D Y C C G +G++C Sbjct: 212 CEVDVNECSSSPCVNGGVCADGLGEYKCICPSGFSGENC 250 Score = 42.3 bits (95), Expect = 0.005 Identities = 52/200 (26%), Positives = 76/200 (38%), Gaps = 30/200 (15%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C S C CV + C C G G +C + C PC D ++ Sbjct: 674 ECSSSPCVNGGLCVDYTNYFECLCHPGYGGDRCEINIDDCANKPCLHNGNCTDYV-NYFT 732 Query: 1573 CACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631 CAC GYT T C E ++C P G +C D+ GY H +C+ + Sbjct: 733 CACAVGYTGRT--C-EVNIDDCSPSPCRHGGSCQ----DLVTGYLCHWPAGFKGSNCETD 785 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPGVIGRACDACAN--AYAEVTPN 1687 EC C N +C A+ C C+PG G C+A + A + N Sbjct: 786 ------IDECATNPC----DNNGTCVDRVASYDCVCKPGFTGTRCEANIDDCATSPCLNN 835 Query: 1688 SGC-EVVYD---GCPRSFAG 1703 + C +++ D CP + G Sbjct: 836 AICTDLINDFHCACPAGYQG 855 Score = 41.9 bits (94), Expect = 0.007 Identities = 47/189 (24%), Positives = 63/189 (33%), Gaps = 32/189 (16%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC + C + C + +C C G G C + C+ PC + G++ Sbjct: 142 DCHSNPCQNNATCQDLINDFSCQCPQGITGQTCNTDIDECQSSPCKHQGTCQNYLG-GFN 200 Query: 1573 CACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCH-- 1627 C C GY+ T E C G G C G+ +C +C Sbjct: 201 CLCRHGYSGITCEVDVNECSSSPCVNGGVCADGLGEYKCICPSGFSGENCQVNIDECASS 260 Query: 1628 -CKENHYKPEGTAECLPCQCYAAGSENSSCEA----------ATG----------QCHCR 1666 CK N E + CQC G + +CE A G QC C Sbjct: 261 PCK-NGATCEDLVDEFRCQCQP-GFKGQNCETNINECIGAACANGSTCIDLVNAYQCTCL 318 Query: 1667 PGVIGRACD 1675 PG GR CD Sbjct: 319 PGFTGRHCD 327 Score = 41.5 bits (93), Expect = 0.009 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C A C NG+ C DL + Y C C G TG+ C Sbjct: 288 CETNINECIGAACANGSTCIDLVNAYQCTCLPGFTGRHC 326 Score = 40.7 bits (91), Expect = 0.016 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 6/65 (9%) Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343 CI D D+K L Y + C + CSS PC G C +L + Y C C +G+ Sbjct: 420 CI-DLVNDYKCSCLQGYTGKD-----CHIDINECSSNPCQYGGTCLNLLNGYACLCIDGY 473 Query: 1344 TGKDC 1348 TG +C Sbjct: 474 TGLNC 478 Score = 40.3 bits (90), Expect = 0.022 Identities = 15/33 (45%), Positives = 18/33 (54%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C S PC N C DL + C C G +GKDC+ Sbjct: 371 CLSRPCLNNGMCLDLVSDFHCTCPTGFSGKDCS 403 Score = 39.5 bits (88), Expect = 0.038 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C S PC +G+ C D +Y C C+ G+TG+ C Sbjct: 326 CDVDIDECQSNPCQHGSACMDGVSSYQCICQPGYTGQYC 364 Score = 39.5 bits (88), Expect = 0.038 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C K + C S+ CY A C D + Y C C G TG C Sbjct: 554 CESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLC 592 Score = 39.5 bits (88), Expect = 0.038 Identities = 40/167 (23%), Positives = 56/167 (33%), Gaps = 13/167 (7%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C++ D C + C CV S C C+ G G +C + C PC + Sbjct: 782 CETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRCEANIDDCATSPC-LNNAICTD 840 Query: 1567 TPKGYSCACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKEN 1623 + CAC GY T + + C G A C G+ +C+ E Sbjct: 841 LINDFHCACPAGYQGQTCAINVDDCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCSIEM 900 Query: 1624 GKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667 +C C N +G + C C A G CE C P Sbjct: 901 DECGSYPCLNNGTCVDGRNR-VTCTC-AVGFTGQFCEVNIDDCDPAP 945 Score = 39.5 bits (88), Expect = 0.038 Identities = 16/40 (40%), Positives = 18/40 (45%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C APC N C DL + C C G TG+ CA Sbjct: 934 CEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCA 973 Score = 39.1 bits (87), Expect = 0.050 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 4/48 (8%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C++ PC + C+D + + C C G+TG+ C D + P R GG Sbjct: 713 CANKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNIDDCSPSPCRHGG 760 Score = 38.7 bits (86), Expect = 0.066 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 1303 DNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYI-CDCKEGHTGKDC 1348 DN C S C + C NG C TY C+C +G+TG DC Sbjct: 508 DNRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYTCECPKGYTGHDC 554 Score = 38.7 bits (86), Expect = 0.066 Identities = 16/33 (48%), Positives = 16/33 (48%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 RC S PC NGA C D C C G TG C Sbjct: 1090 RCHSQPCQNGATCVDDDGVVFCKCAMGFTGTHC 1122 Score = 38.3 bits (85), Expect = 0.088 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C CSS+PC NG C D + + C C G+ G C Sbjct: 668 CERDIDECSSSPCVNGGLCVDYTNYFECLCHPGYGGDRC 706 Score = 37.9 bits (84), Expect = 0.12 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 1039 VTSFTCQCPEGFTGVNCETILTK---ASCEVDGDGSICRSGSQCVARR-EGGILCQ---- 1090 + F+CQCP+G TG C T + + + C+ G G C+ R GI C+ Sbjct: 158 INDFSCQCPQGITGQTCNTDIDECQSSPCKHQGTCQNYLGGFNCLCRHGYSGITCEVDVN 217 Query: 1091 GCSIDAAYTTAVC 1103 CS VC Sbjct: 218 ECSSSPCVNGGVC 230 Score = 37.9 bits (84), Expect = 0.12 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 999 DNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE-T 1057 D C P E C T + A N+ + P+ ++C CP G TG +C+ + Sbjct: 958 DFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL---KGYSCSCPTGVTGRHCDVS 1014 Query: 1058 ILTKASCEVDGDGSICRSGSQCV 1080 I C +G + +SG QC+ Sbjct: 1015 ICDSKPCRNNGSCVLTQSGYQCL 1037 Score = 37.5 bits (83), Expect = 0.15 Identities = 15/41 (36%), Positives = 19/41 (46%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C C++ PC N C D +Y C CK G TG C Sbjct: 780 SNCETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRC 820 Score = 37.1 bits (82), Expect = 0.20 Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 6/42 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV 1080 V F CQC GF G NCET + + G+ C +GS C+ Sbjct: 272 VDEFRCQCQPGFKGQNCETNINECI------GAACANGSTCI 307 Score = 36.7 bits (81), Expect = 0.27 Identities = 14/39 (35%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C CS +PC +G C DL Y+C G G +C Sbjct: 744 CEVNIDDCSPSPCRHGGSCQDLVTGYLCHWPAGFKGSNC 782 Score = 35.9 bits (79), Expect = 0.47 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 4/59 (6%) Query: 1297 LNSYVA---DNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 LN Y D T C + C PC+NG C DL + Y C C + + CA ++ Sbjct: 462 LNGYACLCIDGYTGLNCEKDIDDCLFNPCHNGT-CEDLVNNYKCVCPDNRQERTCAGNS 519 Score = 35.5 bits (78), Expect = 0.62 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 12/68 (17%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI-CRSGSQCVARREGGILCQGCSIDAA 1097 V+ +TC C GFTG+NC S E+D GS C + CV R + C C++ Sbjct: 880 VSGYTCLCMPGFTGINC-------SIEMDECGSYPCLNNGTCVDGR-NRVTCT-CAV--G 928 Query: 1098 YTTAVCEL 1105 +T CE+ Sbjct: 929 FTGQFCEV 936 Score = 35.1 bits (77), Expect = 0.82 Identities = 14/39 (35%), Positives = 17/39 (43%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC N C D + C C G TG+ C Sbjct: 896 CSIEMDECGSYPCLNNGTCVDGRNRVTCTCAVGFTGQFC 934 Score = 34.7 bits (76), Expect = 1.1 Identities = 46/188 (24%), Positives = 63/188 (33%), Gaps = 25/188 (13%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C S C+ S C C+ G G C + C PC C+ + Sbjct: 332 ECQSNPCQHGSACMDGVSSYQCICQPGYTGQYCHIDIDECLSRPCLNNGMCL--DLVSDF 389 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC-NKENGK-CH-- 1627 C C G+ + C + + GS C D+ Y C GK CH Sbjct: 390 HCTCPTGF--SGKDCSVNIDDCADAPCQHGSTC----IDLVNDYKCSCLQGYTGKDCHID 443 Query: 1628 ---CKENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 C N + GT L C C G +CE C P G C+ N Sbjct: 444 INECSSNPCQYGGTCLNLLNGYACLC-IDGYTGLNCEKDIDDCLFNPCHNG-TCEDLVNN 501 Query: 1681 YAEVTPNS 1688 Y V P++ Sbjct: 502 YKCVCPDN 509 Score = 34.7 bits (76), Expect = 1.1 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 4/54 (7%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQ---CVARRE-GGILC 1089 T +TC+CP+G+TG +CE+ + + C G+ C+ R G LC Sbjct: 539 TYYTCECPKGYTGHDCESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLC 592 Score = 34.7 bits (76), Expect = 1.1 Identities = 13/33 (39%), Positives = 16/33 (48%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C+ PC G C D Y C C G TG +C+ Sbjct: 865 CTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCS 897 Score = 33.5 bits (73), Expect = 2.5 Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG---SQCVARREGGILCQGCSID 1095 V ++ C C GFTG +C+ + + GS C G QC+ + G Q C ID Sbjct: 310 VNAYQCTCLPGFTGRHCDVDIDECQSNPCQHGSACMDGVSSYQCIC--QPGYTGQYCHID 367 Score = 33.5 bits (73), Expect = 2.5 Identities = 15/40 (37%), Positives = 17/40 (42%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDC 1348 C C + PC N A C D Y C C G TG+ C Sbjct: 972 CATPIDLCEAHPCQNNATCRMDPLKGYSCSCPTGVTGRHC 1011 Score = 32.7 bits (71), Expect = 4.4 Identities = 11/35 (31%), Positives = 18/35 (51%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 F C C G++G+ CE + + S +G +C G Sbjct: 199 FNCLCRHGYSGITCEVDVNECSSSPCVNGGVCADG 233 Score = 32.7 bits (71), Expect = 4.4 Identities = 44/173 (25%), Positives = 54/173 (31%), Gaps = 24/173 (13%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQTPKGYS 1572 DC+ + C C ++ C C R C S C+ C Y+ Sbjct: 484 DCLFNPCHN-GTCEDLVNNYKCVCPDNRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYT 542 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCAC-DVTRGYHPHCNKENGKCHCKEN 1631 C C GYT C ES C S G C D Y C + C N Sbjct: 543 CECPKGYT--GHDC-ESKINYCKSS----SCYGNATCLDGANNYTCICPRGFTGTLCDVN 595 Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYA 1682 EC C + +SCE +CHC G GR C N A Sbjct: 596 ------VDECEDSPC----ANGASCEDLINDFRCHCPAGFQGRTCAVDINECA 638 Score = 32.3 bits (70), Expect = 5.8 Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 13/78 (16%) Query: 1009 NFEECLTVLKFGNASGFVNSDSVLFRPIYP-------VTSFTCQCPEGFTGVNCETILTK 1061 N+ ECL +G +N D +P V FTC C G+TG CE + Sbjct: 691 NYFECLCHPGYGGDRCEINIDDCANKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNID- 749 Query: 1062 ASCEVDGDGSICRSGSQC 1079 D S CR G C Sbjct: 750 -----DCSPSPCRHGGSC 762 Score = 31.9 bits (69), Expect = 7.6 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 6/39 (15%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079 ++TC CP GFTG C+ + + CE S C +G+ C Sbjct: 578 NYTCICPRGFTGTLCDVNVDE--CE----DSPCANGASC 610 Score = 31.9 bits (69), Expect = 7.6 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 1039 VTSFTCQCPEGFTGVNCETILTK-ASCEVDGDGS-ICRSGS-QCVARRE-GGILCQG--- 1091 VT + C P GF G NCET + + A+ D +G+ + R S CV + G C+ Sbjct: 766 VTGYLCHWPAGFKGSNCETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRCEANID 825 Query: 1092 -CSIDAAYTTAVC 1103 C+ A+C Sbjct: 826 DCATSPCLNNAIC 838 >SB_40912| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 634 Score = 49.6 bits (113), Expect = 4e-05 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 5/100 (5%) Query: 1485 CIQDVRIGTAQSLLNRPTVRENVRD-GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGR 1543 C QD+ + LN T ++V C +C + C + C + TC+C+ G Sbjct: 195 CQQDINECQSNPCLNGATCTDHVNGYTCSYINECQSNPCLNGATCTDHVNGYTCSCKLGY 254 Query: 1544 VGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580 G C ++ C+ PC D GY+C+C+ GYT Sbjct: 255 TGIVCQQDINECQSNPCLNGATCTDHV-NGYTCSCKLGYT 293 Score = 49.2 bits (112), Expect = 5e-05 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 10/69 (14%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD----------STGPPWRFG 1359 C + + C S PC NGA C+D + Y C CK G+TG C ST P W Sbjct: 259 CQQDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVCQQVSSSQFLEPTSTTPQWALL 318 Query: 1360 GDGMLSFNP 1368 M + NP Sbjct: 319 STSMFTINP 327 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/39 (43%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC NGA C+D + Y C C G+TG +C Sbjct: 157 CETDINECQSNPCLNGATCTDHVNGYTCSCALGYTGIEC 195 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/34 (50%), Positives = 21/34 (61%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C S PC NGA C+D + Y C CK G+TG C Sbjct: 226 NECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVC 259 Score = 40.7 bits (91), Expect = 0.016 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 1315 SRCSSAPCYNGAECSDLW--DTYICDCKEGHTGKDC 1348 S C S PC +G+ C + DTY C C +G+TG+ C Sbjct: 122 SPCQSDPCLHGSRCLATYTDDTYTCACLQGYTGRHC 157 Score = 37.9 bits (84), Expect = 0.12 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 16/112 (14%) Query: 998 DDNICVHEPCLNFEECLTVLKFGNASGFVN---SDSVLFRPIYP--VTSFTCQCPEGFTG 1052 D N C PCLN C + G ++N S+ L V +TC C G+TG Sbjct: 198 DINECQSNPCLNGATCTDHVN-GYTCSYINECQSNPCLNGATCTDHVNGYTCSCKLGYTG 256 Query: 1053 VNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 + C+ + + C+ + C +G+ C G CS YT VC+ Sbjct: 257 IVCQQDINE--CQ----SNPCLNGATCTDHVNG----YTCSCKLGYTGIVCQ 298 Score = 35.5 bits (78), Expect = 0.62 Identities = 34/134 (25%), Positives = 49/134 (36%), Gaps = 11/134 (8%) Query: 1550 SACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPC 1607 S C+ PC +RC+ T Y+CAC GY T C E+ EC G+ C Sbjct: 122 SPCQSDPCLHGSRCLATYTDDTYTCACLQGY--TGRHC-ETDINECQSNPCLNGATC--- 175 Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667 D GY C C+++ + + CL +C + +C P Sbjct: 176 -TDHVNGYTCSCALGYTGIECQQDINECQSN-PCLNGATCTDHVNGYTC-SYINECQSNP 232 Query: 1668 GVIGRACDACANAY 1681 + G C N Y Sbjct: 233 CLNGATCTDHVNGY 246 Score = 34.3 bits (75), Expect = 1.4 Identities = 37/175 (21%), Positives = 66/175 (37%), Gaps = 11/175 (6%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICD---------CKEGHTGKDCADSTGPPWRFGG 1360 C + + C S PC NGA C+D + Y C C G T D + + G Sbjct: 195 CQQDINECQSNPCLNGATCTDHVNGYTCSYINECQSNPCLNGATCTDHVNGYTCSCKLGY 254 Query: 1361 DGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQL-KSGLLHYSYNGETMYLPMATLS 1419 G++ + P LN + T + + S +L +G++ + P +T Sbjct: 255 TGIVCQQDINECQSNPCLNGATC-TDHVNGYTCSCKLGYTGIVCQQVSSSQFLEPTSTTP 313 Query: 1420 DGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGL 1474 A + + + + RT ++ ++A K Q + K+ + AGL Sbjct: 314 QWALLSTSMFTINPEEVMITSKFERTRVLNLIAGKFQLTKVHKLYVYTRQKRAGL 368 Score = 33.9 bits (74), Expect = 1.9 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 10/68 (14%) Query: 1037 YPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDA 1096 Y ++TC C +G+TG +CET + + C+ + C +G+ C G CS Sbjct: 139 YTDDTYTCACLQGYTGRHCETDINE--CQ----SNPCLNGATCTDHVNG----YTCSCAL 188 Query: 1097 AYTTAVCE 1104 YT C+ Sbjct: 189 GYTGIECQ 196 Score = 33.5 bits (73), Expect = 2.5 Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 4/62 (6%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TC+C G G +C ++ C+ PC D GY+ Sbjct: 163 ECQSNPCLNGATCTDHVNGYTCSCALGYTGIECQQDINECQSNPCLNGATCTDHV-NGYT 221 Query: 1573 CA 1574 C+ Sbjct: 222 CS 223 >SB_50709| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 953 Score = 49.2 bits (112), Expect = 5e-05 Identities = 18/32 (56%), Positives = 23/32 (71%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S PC NGA+C+++ D Y C CK G TGK+C Sbjct: 581 CDSNPCNNGAQCNNMVDGYRCMCKSGFTGKNC 612 Score = 43.2 bits (97), Expect = 0.003 Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 C + C++ PC NG C D + ++C C G TG+ C +T Sbjct: 612 CEVEEDECTTNPCANGGACVDKINGFVCTCPSGFTGQFCEKAT 654 Score = 42.7 bits (96), Expect = 0.004 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 7/74 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA---CELGPC-GAARCVPD 1565 C+ D C + C CV + CTC +G G C A C+ G C +CV Sbjct: 612 CEVEEDECTTNPCANGGACVDKINGFVCTCPSGFTGQFCEKATVDCKPGACRNNGKCV-- 669 Query: 1566 QTPKGYSCACEPGY 1579 + P G+ C C GY Sbjct: 670 EIPGGFQCLCSDGY 683 Score = 35.9 bits (79), Expect = 0.47 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 10/66 (15%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 V + C C GFTG NCE + + C + C +G CV + G + C+ + + Sbjct: 596 VDGYRCMCKSGFTGKNCE--VEEDECTTNP----CANGGACVDKINGFV----CTCPSGF 645 Query: 1099 TTAVCE 1104 T CE Sbjct: 646 TGQFCE 651 Score = 35.1 bits (77), Expect = 0.82 Identities = 18/67 (26%), Positives = 26/67 (38%), Gaps = 4/67 (5%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSC 1573 C + C ++C D C C++G G C C PC D+ G+ C Sbjct: 581 CDSNPCNNGAQCNNMVDGYRCMCKSGFTGKNCEVEEDECTTNPCANGGACVDKI-NGFVC 639 Query: 1574 ACEPGYT 1580 C G+T Sbjct: 640 TCPSGFT 646 >SB_22953| Best HMM Match : EGF_2 (HMM E-Value=1.3e-14) Length = 635 Score = 49.2 bits (112), Expect = 5e-05 Identities = 48/201 (23%), Positives = 63/201 (31%), Gaps = 16/201 (7%) Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGY 1571 QS C IC CTC G GP C AC LG + Sbjct: 90 QSGNSCPTPICSKGCAQGVCVKPDNCTCHPGYDGPSCDQACTLGRWDVNCNNTCECQNNS 149 Query: 1572 SCACEPGYTLTTSGCI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 +C G TSG ++ + C G++G S C C CN G C C Sbjct: 150 TCDSVQGICNCTSGWQGDACQLPCKSGYYGNSCKQVCQCQ----NRSRCNHVTGLCRCIS 205 Query: 1631 NHYKPEGTAEC------LPCQCYAAGSENSSCEAATGQC--HCRPGVIGRACD---ACAN 1679 C C+ ++C+ TG+C C G G C ACA+ Sbjct: 206 GWTGKRCERPCDSGYYGDECKRVCQCMNGATCDHVTGRCDQRCPVGTYGFDCAKVCACAD 265 Query: 1680 AYAEVTPNSGCEVVYDGCPRS 1700 + C + C S Sbjct: 266 TEKCSVVSGECTCIAGSCSSS 286 >SB_3431| Best HMM Match : EGF (HMM E-Value=1.8e-08) Length = 480 Score = 49.2 bits (112), Expect = 5e-05 Identities = 16/38 (42%), Positives = 25/38 (65%) Query: 1311 PEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 P + + C S+PC NG C+D + Y C C+ G+TG++C Sbjct: 191 PNEINECDSSPCKNGGNCTDQVNNYTCTCQPGYTGRNC 228 Score = 33.5 bits (73), Expect = 2.5 Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 1546 PQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580 P ++ C+ PC DQ Y+C C+PGYT Sbjct: 191 PNEINECDSSPCKNGGNCTDQV-NNYTCTCQPGYT 224 Score = 32.7 bits (71), Expect = 4.4 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACEL 1554 +C S C C ++ TCTC+ G G C AC + Sbjct: 196 ECDSSPCKNGGNCTDQVNNYTCTCQPGYTGRNCEIACSV 234 >SB_12832| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1169 Score = 48.8 bits (111), Expect = 6e-05 Identities = 64/250 (25%), Positives = 88/250 (35%), Gaps = 33/250 (13%) Query: 1506 NVRDGCQSRADCMLSICPPYSKCVTSW--DSSTCTCEAGRVGPQCVSACELGPCGAARCV 1563 N ++G + A C + CPP C S D + C AG PQ PC A Sbjct: 384 NSKNGSANNAAC--TSCPPGYYCQDSGLSDYTPYLCPAGHYCPQATKYSREFPCPAGTYN 441 Query: 1564 PDQTPKGYSCACE--PGYTLTTSGCIESGKEECPGGWW---GGSACGPCACDVTRGYHPH 1618 PD + AC+ P T G + +CP G++ G A AC GY+ Sbjct: 442 PDTNATTQTPACQTCPARKYCTRGSVTPA--DCPPGYYCPEGTRAGNQFACHA--GYYSD 497 Query: 1619 CNKENGKCHCKE---NHYKPEGT---AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGR 1672 + CK +Y P+GT A P C G+ N + +C G Sbjct: 498 VTGLSNYTECKSCPPGYYCPDGTSQEATITPLPC-PIGTYNPEWNIGY-KINCVRCTAGM 555 Query: 1673 ACDACANAYAEVTPNSGCEVVYDG--CPRSFAGGVWWPRTKFGVETITDCPPGSSGRATR 1730 C + A V Y+G CP A G +P T D P ++ Sbjct: 556 FCPSAGQTNAS-------HVCYEGYYCPNGTAAGDQFPCPP---GTYGDRPGLTAAEECL 605 Query: 1731 TCDETKDVPW 1740 C +TK W Sbjct: 606 RCPQTKSCGW 615 Score = 33.9 bits (74), Expect = 1.9 Identities = 35/130 (26%), Positives = 48/130 (36%), Gaps = 14/130 (10%) Query: 1522 CPPYSKCV--TSWDSSTCT--CEAGRVGPQCVSACELG--PCGAARCVPDQTPKGYSCAC 1575 CPP C TS +++ C G P+ ++ C A P S C Sbjct: 510 CPPGYYCPDGTSQEATITPLPCPIGTYNPEWNIGYKINCVRCTAGMFCPSAGQTNASHVC 569 Query: 1576 EPGYTLTTSGCIESGKEECPGGWWGG----SACGPCA-CDVTR--GYHPHCNKENGKCHC 1628 GY +G + CP G +G +A C C T+ G+ N N C Sbjct: 570 YEGY-YCPNGTAAGDQFPCPPGTYGDRPGLTAAEECLRCPQTKSCGWGTGLNNNNTWQDC 628 Query: 1629 KENHYKPEGT 1638 + HY PEGT Sbjct: 629 RPGHYCPEGT 638 >SB_40516| Best HMM Match : Cadherin (HMM E-Value=0.042) Length = 126 Score = 48.4 bits (110), Expect = 8e-05 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 4/80 (5%) Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGG 663 ATD+D G+NG + Y + + F I+P SG IRT D++ + A D G Sbjct: 27 ATDSDTGINGVVEYRI---SEDTDLFYIEPTSGTIRTADIFADKDRGLSFSFMVQASDKG 83 Query: 664 TPPQSSTVIVHIKIEDINDS 683 TPP+ + HI I + DS Sbjct: 84 TPPKKTKENAHITIFLLRDS 103 Score = 37.5 bits (83), Expect = 0.15 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIRAQ 230 A KATD+D G N + Y I +T + F I+ SG + D ++ S+ +++A Sbjct: 23 AGTKATDSDTGINGVVEYR-ISEDTDL-FYIEPTSGTIRTADIFADKDRGLSFSFMVQAS 80 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 D G+P + I I + D+ TS Sbjct: 81 DKGTPPKKTKENAHITIFLLRDSNSMVLTS 110 Score = 35.1 bits (77), Expect = 0.82 Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 11/101 (10%) Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL-DRETMSGYLLTV 551 ATDSD GIN + Y +S + F I P +G I T + D++ + V Sbjct: 27 ATDSDTGINGVVEYRISED---------TDLFYIEPTSGTIRTADIFADKDRGLSFSFMV 77 Query: 552 TARDGGVPSLSDTTDVEISVVDVND-NEPVFKQQLYTANIM 591 A D G P + I++ + D N V ++ +I+ Sbjct: 78 QASDKGTPPKKTKENAHITIFLLRDSNSMVLTSKMSKEDIL 118 Score = 34.3 bits (75), Expect = 1.4 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 7/74 (9%) Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL-DRETQAKY 332 Y +A D+D G+N + Y +++ + DL I+P SG + T+ D++ + Sbjct: 20 YLAAGTKATDSDTGINGVVEYRISE-----DTDL-FYIEPTSGTIRTADIFADKDRGLSF 73 Query: 333 QLLVTATDGGDPPR 346 +V A+D G PP+ Sbjct: 74 SFMVQASDKGTPPK 87 >SB_23966| Best HMM Match : EGF (HMM E-Value=2.4e-40) Length = 167 Score = 48.4 bits (110), Expect = 8e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 9/98 (9%) Query: 1487 QDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGP 1546 +D+ GTA+ ++ +NVR + +C + C +KC + TC C G G Sbjct: 30 KDILEGTARRVIFD---EKNVRKLINNINECQSNPCLNGAKCNDHVNGYTCKCAPGYTGI 86 Query: 1547 QC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 C ++ C+ PC A C + GY+C C PGYT Sbjct: 87 VCQQDINECQSNPCLNGATC--NDHVNGYTCKCAPGYT 122 Score = 44.4 bits (100), Expect = 0.001 Identities = 17/39 (43%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C S PC NGA C+D + Y C C G+TG C Sbjct: 88 CQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVC 126 Score = 44.4 bits (100), Expect = 0.001 Identities = 17/39 (43%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C S PC NGA C+D + Y C C G+TG C Sbjct: 126 CQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVC 164 Score = 42.7 bits (96), Expect = 0.004 Identities = 16/34 (47%), Positives = 21/34 (61%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C S PC NGA+C+D + Y C C G+TG C Sbjct: 55 NECQSNPCLNGAKCNDHVNGYTCKCAPGYTGIVC 88 Score = 42.3 bits (95), Expect = 0.005 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 6/69 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C + C + TC C G G C ++ C+ PC A C + GY Sbjct: 94 ECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVCQQDINECQSNPCLNGATC--NDHVNGY 151 Query: 1572 SCACEPGYT 1580 +C C PGYT Sbjct: 152 TCKCAPGYT 160 Score = 37.5 bits (83), Expect = 0.15 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 17/127 (13%) Query: 1549 VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPC 1607 ++ C+ PC A+C + GY+C C PGYT C + E G+ C Sbjct: 54 INECQSNPCLNGAKC--NDHVNGYTCKCAPGYTGIV--CQQDINECQSNPCLNGATCN-- 107 Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667 D GY C C+++ EC C + N T C C P Sbjct: 108 --DHVNGYTCKCAPGYTGIVCQQD------INECQSNPCLNGATCNDHVNGYT--CKCAP 157 Query: 1668 GVIGRAC 1674 G G C Sbjct: 158 GYTGIVC 164 Score = 33.1 bits (72), Expect = 3.3 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 4/56 (7%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQC-VARREGGILCQ 1090 V +TC+C G+TG+ C+ + + +G+ C +G C A GI+CQ Sbjct: 72 VNGYTCKCAPGYTGIVCQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVCQ 127 Score = 33.1 bits (72), Expect = 3.3 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 4/56 (7%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQC-VARREGGILCQ 1090 V +TC+C G+TG+ C+ + + +G+ C +G C A GI+CQ Sbjct: 110 VNGYTCKCAPGYTGIVCQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVCQ 165 >SB_16748| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 280 Score = 48.4 bits (110), Expect = 8e-05 Identities = 18/39 (46%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC NGA C+D ++Y C CK G TG +C Sbjct: 239 CDNDIDECASNPCQNGATCNDGVNSYTCSCKPGFTGTNC 277 Score = 47.6 bits (108), Expect = 1e-04 Identities = 39/142 (27%), Positives = 53/142 (37%), Gaps = 18/142 (12%) Query: 1537 CTCEAGRVGPQCVS---ACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593 C C G G +C + C+ PC + D+ GY+CAC PG+ T C E+ E Sbjct: 152 CLCPEGFSGDKCENHDNECQSSPCKNSGTCKDED-NGYTCACVPGF--TDKNC-ETDINE 207 Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653 C G A G D G+ C C + EC C + N Sbjct: 208 CAG---DPCANGGTCTDGINGFTCTCPAGYNGSTCDND------IDECASNPCQNGATCN 258 Query: 1654 SSCEAATGQCHCRPGVIGRACD 1675 + T C C+PG G C+ Sbjct: 259 DGVNSYT--CSCKPGFTGTNCE 278 Score = 43.6 bits (98), Expect = 0.002 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 6/71 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C C C + TCTC AG G C + C PC A C + Y Sbjct: 207 ECAGDPCANGGTCTDGINGFTCTCPAGYNGSTCDNDIDECASNPCQNGATC--NDGVNSY 264 Query: 1572 SCACEPGYTLT 1582 +C+C+PG+T T Sbjct: 265 TCSCKPGFTGT 275 Score = 40.7 bits (91), Expect = 0.016 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 7/64 (10%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362 C + C S+PC N C D + Y C C G T K+C + G P GG DG Sbjct: 163 CENHDNECQSSPCKNSGTCKDEDNGYTCACVPGFTDKNCETDINECAGDPCANGGTCTDG 222 Query: 1363 MLSF 1366 + F Sbjct: 223 INGF 226 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+ PC NG C+D + + C C G+ G C Sbjct: 201 CETDINECAGDPCANGGTCTDGINGFTCTCPAGYNGSTC 239 Score = 37.1 bits (82), Expect = 0.20 Identities = 26/113 (23%), Positives = 37/113 (32%), Gaps = 7/113 (6%) Query: 1509 DGCQSRA-DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVP 1564 D C++ +C S C C + TC C G C ++ C PC Sbjct: 161 DKCENHDNECQSSPCKNSGTCKDEDNGYTCACVPGFTDKNCETDINECAGDPCANGGTCT 220 Query: 1565 DQTPKGYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615 D G++C C GY +T + E C G C G+ Sbjct: 221 DGI-NGFTCTCPAGYNGSTCDNDIDECASNPCQNGATCNDGVNSYTCSCKPGF 272 Score = 36.3 bits (80), Expect = 0.35 Identities = 13/19 (68%), Positives = 14/19 (73%) Query: 1039 VTSFTCQCPEGFTGVNCET 1057 V S+TC C GFTG NCET Sbjct: 261 VNSYTCSCKPGFTGTNCET 279 Score = 35.1 bits (77), Expect = 0.82 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC C GFT NCET + + + G C +G C GI C+ A Y + Sbjct: 188 YTCACVPGFTDKNCETDINECA------GDPCANGGTCT----DGINGFTCTCPAGYNGS 237 Query: 1102 VCE 1104 C+ Sbjct: 238 TCD 240 Score = 34.3 bits (75), Expect = 1.4 Identities = 11/38 (28%), Positives = 19/38 (50%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 + FTC CP G+ G C+ + + + +G+ C G Sbjct: 223 INGFTCTCPAGYNGSTCDNDIDECASNPCQNGATCNDG 260 >SB_3457| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 848 Score = 48.4 bits (110), Expect = 8e-05 Identities = 51/186 (27%), Positives = 67/186 (36%), Gaps = 21/186 (11%) Query: 1508 RDGCQSRADCMLSICPPYSKCV-TSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARC 1562 RD + + C S C + C+ T DS C C G C + C+ PC C Sbjct: 528 RDCGERVSSCESSPCENGATCIETDHDSFRCECTDKYGGHLCRDIIDPCQRNPCLNGGHC 587 Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWW-GGSACGPCACDVTRGYHPHCNK 1621 Y CAC GY+ TT C + EC G G C C GY+ Sbjct: 588 T--SAGDSYKCACNEGYSGTT--CEVTLHTECMDCHVNAGCTDGKCVCH--SGYY----- 636 Query: 1622 ENGKCHCKENHYKP-EGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 NG HC+ P + + CL C G+ E +C C G G C+ A Sbjct: 637 GNGH-HCEPLPAAPTKPPSPCLSNPCRHGGT--CMDEGGKFRCVCADGYKGELCEKKAQH 693 Query: 1681 YAEVTP 1686 + P Sbjct: 694 FCHPNP 699 Score = 42.7 bits (96), Expect = 0.004 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDL-WDTYICDCKEGHTGKDCADSTGP 1354 C E+ S C S+PC NGA C + D++ C+C + + G C D P Sbjct: 530 CGERVSSCESSPCENGATCIETDHDSFRCECTDKYGGHLCRDIIDP 575 Score = 42.3 bits (95), Expect = 0.005 Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C PC NG C+ D+Y C C EG++G C Sbjct: 569 CRDIIDPCQRNPCLNGGHCTSAGDSYKCACNEGYSGTTC 607 Score = 36.3 bits (80), Expect = 0.35 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%) Query: 1315 SRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADS 1351 ++C PC NGA C + D+ Y C CK G G +C ++ Sbjct: 457 NKCLPNPCKNGAMCVEHGDSTEYSCICKSGFKGSNCEEA 495 Score = 35.5 bits (78), Expect = 0.62 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 6/49 (12%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQ 1090 F C+CP GFTG +C + +SCE S C +G+ C+ C+ Sbjct: 517 FVCRCPAGFTGRDCGERV--SSCE----SSPCENGATCIETDHDSFRCE 559 Score = 35.1 bits (77), Expect = 0.82 Identities = 13/42 (30%), Positives = 17/42 (40%) Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355 R++C PC N C+ Y C C G G+ C P Sbjct: 294 RAKCEPNPCLNDGVCTAFLHDYECACPAGFMGRHCEGKVSNP 335 Score = 34.3 bits (75), Expect = 1.4 Identities = 11/29 (37%), Positives = 16/29 (55%) Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C NG C + ++C C G TG+DC + Sbjct: 504 CKNGGTCMNGQQMFVCRCPAGFTGRDCGE 532 Score = 33.9 bits (74), Expect = 1.9 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 1307 LAGCPEKR-SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 L P K S C S PC +G C D + C C +G+ G+ C Sbjct: 645 LPAAPTKPPSPCLSNPCRHGGTCMDEGGKFRCVCADGYKGELC 687 Score = 32.7 bits (71), Expect = 4.4 Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 1310 CPEKRSR-CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C +K C PC +G C + D Y C C + G+ C Sbjct: 687 CEKKAQHFCHPNPCLHGGTCDEKEDGYTCRCIGAYRGEHC 726 >SB_52148| Best HMM Match : EGF (HMM E-Value=0) Length = 1055 Score = 48.0 bits (109), Expect = 1e-04 Identities = 43/162 (26%), Positives = 61/162 (37%), Gaps = 25/162 (15%) Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTL 1581 + CVT D+ C C+ G G +C + C+L PC T +G+ C C+ GY Sbjct: 855 HGHCVTRRDALFCQCDFGYYGAECDRRMDYCKLKPCVVENGWCVNTQQGFRCVCKRGY-- 912 Query: 1582 TTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG----KC-----HCKEN- 1631 G K C C P +TR P C G +C HC N Sbjct: 913 --GGLRCHKKNACL-----PDPCAPHGICMTRRGDPFCVCTEGYTGLRCKVVINHCLSNP 965 Query: 1632 --HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIG 1671 + T+ C+C G + + CE A C+ P + G Sbjct: 966 CLNGVCVSTSSTYTCRC-TVGFKGTRCEHAMNTCYSNPCIHG 1006 Score = 44.8 bits (101), Expect = 0.001 Identities = 48/171 (28%), Positives = 62/171 (36%), Gaps = 29/171 (16%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQT 1567 C + CM C + CV+S C C AG +G C CE PC C ++ Sbjct: 769 CTTADPCMRLACV-HGACVSSNGVVRCECSAGYLGKSCNMTDPCEPSPCLNGGSCT--KS 825 Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC--NKENGK 1625 +SC C PGY G S + C G A PC H HC ++ Sbjct: 826 GLAHSCECTPGY----EGANCSITKRC------GDA--PCR-------HGHCVTRRDALF 866 Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSC-EAATG-QCHCRPGVIGRAC 1674 C C +Y E C+ EN C G +C C+ G G C Sbjct: 867 CQCDFGYYGAECDRRMDYCKLKPCVVENGWCVNTQQGFRCVCKRGYGGLRC 917 Score = 43.2 bits (97), Expect = 0.003 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 5/72 (6%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQT 1567 C + C+ C P+ C+T C C G G +C ++ C PC CV T Sbjct: 917 CHKKNACLPDPCAPHGICMTRRGDPFCVCTEGYTGLRCKVVINHCLSNPCLNGVCV--ST 974 Query: 1568 PKGYSCACEPGY 1579 Y+C C G+ Sbjct: 975 SSTYTCRCTVGF 986 Score = 39.5 bits (88), Expect = 0.038 Identities = 38/134 (28%), Positives = 48/134 (35%), Gaps = 18/134 (13%) Query: 1520 SICPPYS----KCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 S C P S +CV + +S+C C G G C +SACE PC C+ + Y Sbjct: 347 SACKPTSCVNGECVGNGHNSSCKCWKGYSGASCDVKISACEHRPCVQGVCIGRENFTLYH 406 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632 C Y T C E C W G C + G H C G + H Sbjct: 407 CKWNRLY--TGRNC-EIKLSLCA---WDSCGFGECV-KTSNGTHWRCVGHVGNTGERFEH 459 Query: 1633 Y----KPEGTAECL 1642 Y P G C+ Sbjct: 460 YMCASTPRGNRTCM 473 Score = 37.9 bits (84), Expect = 0.12 Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 4/40 (10%) Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDCADSTGPP 1355 C S PC G C +L TY+C CKEG TG C TG P Sbjct: 274 CQSNPCGRGL-CKELTRTTYMCICKEGFTGTHC--ETGTP 310 Score = 36.7 bits (81), Expect = 0.27 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 5/56 (8%) Query: 1528 CVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQTPKGYSCACEPGYT 1580 C S S TC C +G GP C SAC+ C CV + SC C GY+ Sbjct: 322 CTESNSSFTCECFSGYTGPTCAVVESACKPTSCVNGECVGN--GHNSSCKCWKGYS 375 Score = 36.3 bits (80), Expect = 0.35 Identities = 42/162 (25%), Positives = 51/162 (31%), Gaps = 32/162 (19%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACE 1576 C S C + C+ + D C R Q + CE PC C P ++C C Sbjct: 709 CQFSHCI-HGNCMVTLDGHRCA----RCSEQAMDPCESNPCVHGTCRPRN--DSFTCQCF 761 Query: 1577 PGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCKENHY- 1633 GY G+ C C AC H C NG +C C + Sbjct: 762 EGYI---------GR-LCT----TADPCMRLAC-----VHGACVSSNGVVRCECSAGYLG 802 Query: 1634 -KPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 T C P C GS S C C PG G C Sbjct: 803 KSCNMTDPCEPSPCLNGGSCTKS--GLAHSCECTPGYEGANC 842 Score = 35.5 bits (78), Expect = 0.62 Identities = 11/33 (33%), Positives = 18/33 (54%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C +PC NG C+ + C+C G+ G +C+ Sbjct: 811 CEPSPCLNGGSCTKSGLAHSCECTPGYEGANCS 843 Score = 35.1 bits (77), Expect = 0.82 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C PC NG C++ ++ C+C G+TG CA Sbjct: 305 CETGTPLCLPNPCING-NCTESNSSFTCECFSGYTGPTCA 343 Score = 34.7 bits (76), Expect = 1.1 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 8/84 (9%) Query: 1537 CTCEAGRVGPQCVSA---CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESG--K 1591 C C+ G G C + C PC C ++ ++C C GYT T +ES Sbjct: 294 CICKEGFTGTHCETGTPLCLPNPCINGNCT--ESNSSFTCECFSGYTGPTCAVVESACKP 351 Query: 1592 EECPGGWWGGSACGPCACDVTRGY 1615 C G G+ +C +GY Sbjct: 352 TSCVNGECVGNGHN-SSCKCWKGY 374 Score = 34.7 bits (76), Expect = 1.1 Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 1303 DNGTLAGCPEKR-SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 D A C E+ C S PC +G C D++ C C EG+ G+ C Sbjct: 724 DGHRCARCSEQAMDPCESNPCVHGT-CRPRNDSFTCQCFEGYIGRLC 769 Score = 34.3 bits (75), Expect = 1.4 Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 12/64 (18%) Query: 1043 TCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAV 1102 +C+C G+ G NC +TK C GD CR G CV RR+ + CQ C D Y A Sbjct: 830 SCECTPGYEGANCS--ITK-RC---GDAP-CRHG-HCVTRRD-ALFCQ-C--DFGYYGAE 877 Query: 1103 CELR 1106 C+ R Sbjct: 878 CDRR 881 Score = 32.3 bits (70), Expect = 5.8 Identities = 11/18 (61%), Positives = 14/18 (77%) Query: 1040 TSFTCQCPEGFTGVNCET 1057 T++ C C EGFTG +CET Sbjct: 290 TTYMCICKEGFTGTHCET 307 Score = 32.3 bits (70), Expect = 5.8 Identities = 15/39 (38%), Positives = 16/39 (41%), Gaps = 1/39 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC NG C TY C C G G C Sbjct: 954 CKVVINHCLSNPCLNGV-CVSTSSTYTCRCTVGFKGTRC 991 >SB_48268| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 4527 Score = 48.0 bits (109), Expect = 1e-04 Identities = 48/173 (27%), Positives = 61/173 (35%), Gaps = 29/173 (16%) Query: 1522 CPPY-SKCVTSWDSSTCTCEAGRVGP--QCVSACELGPCGAARCVPD-----QTPKGYSC 1573 C P S C + S TC+C AG G CV + GA C P T Y+C Sbjct: 604 CAPIGSSCTNNAGSYTCSCNAGYAGDGETCVEDIDECSSGAHTCAPSGSTCTNTVGSYTC 663 Query: 1574 ACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHY 1633 AC GYT C++ +EC G C P T + C C Y Sbjct: 664 ACNVGYTGDGETCVDI--DECSA---GSHTCAPSVSTCTN------TVGSFTCACNAG-Y 711 Query: 1634 KPEGTA-----ECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIGRACDACAN 1679 +G A EC + S+C G C C G G + CA+ Sbjct: 712 TGDGEACTDIDECTD-GVHTCALNGSTCTNTVGSYTCACNAGYTGNG-ETCAD 762 Score = 42.3 bits (95), Expect = 0.005 Identities = 42/164 (25%), Positives = 59/164 (35%), Gaps = 23/164 (14%) Query: 1521 ICPPY-SKCVTSWDSSTCTCEAGRVGPQCVSACELGPC--GAARCVP-----DQTPKGYS 1572 +C P S C + + TC C AG G V+ ++ C G C P Y+ Sbjct: 561 LCAPSGSTCTNTVGAFTCACNAGYTG-DGVTCTDIDECSDGTNTCAPIGSSCTNNAGSYT 619 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632 C+C GY C+E +EC G C P T + C C Sbjct: 620 CSCNAGYAGDGETCVED-IDECSS---GAHTCAPSGSTCTNTVGSY------TCACNVG- 668 Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676 Y +G C+ +AGS +C + C G AC+A Sbjct: 669 YTGDGET-CVDIDECSAGSH--TCAPSVSTCTNTVGSFTCACNA 709 Score = 41.1 bits (92), Expect = 0.012 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 7/80 (8%) Query: 1547 QCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606 +C +A PC CV T GY C C PGY L + I S +EC G C P Sbjct: 467 ECSAAALHPPCDTL-CVVADTDSGYQCLCNPGYHLDSDPHICSDIDECTS---GSHTCAP 522 Query: 1607 C--ACDVTRGYHPHCNKENG 1624 C T G + C ++G Sbjct: 523 SGGVCTNTMGSYT-CACDSG 541 Score = 39.1 bits (87), Expect = 0.050 Identities = 38/158 (24%), Positives = 54/158 (34%), Gaps = 17/158 (10%) Query: 1523 PPYSKCVTSWDSSTCTCEAGRVGPQ--C--VSACELGP--CGAARCVPDQTPKGYSCACE 1576 P C + S TC C++G G C + C G C + T ++CAC Sbjct: 522 PSGGVCTNTMGSYTCACDSGYTGDGQICTDIDECSSGGHLCAPSGSTCTNTVGAFTCACN 581 Query: 1577 PGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKCHCKENHYKP 1635 GYT C + +EC G + C P T + C+ G + + Sbjct: 582 AGYTGDGVTCTDI--DECSD---GTNTCAPIGSSCTNNAGSYTCSCNAG--YAGDGETCV 634 Query: 1636 EGTAECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIG 1671 E EC + S+C G C C G G Sbjct: 635 EDIDEC-SSGAHTCAPSGSTCTNTVGSYTCACNVGYTG 671 Score = 34.7 bits (76), Expect = 1.1 Identities = 35/110 (31%), Positives = 43/110 (39%), Gaps = 13/110 (11%) Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP--CACDVTRG 1614 C + V T Y+CAC+ GY T G I + +EC GG C P C T G Sbjct: 520 CAPSGGVCTNTMGSYTCACDSGY--TGDGQICTDIDECSS---GGHLCAPSGSTCTNTVG 574 Query: 1615 -YHPHCNK--ENGKCHCKENHYKPEGTAECLP--CQC-YAAGSENSSCEA 1658 + CN C + +GT C P C AGS SC A Sbjct: 575 AFTCACNAGYTGDGVTCTDIDECSDGTNTCAPIGSSCTNNAGSYTCSCNA 624 Score = 32.7 bits (71), Expect = 4.4 Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 4/55 (7%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093 V S+TC C G+TG N ET C V G + SGS C G +C CS Sbjct: 742 VGSYTCACNAGYTG-NGETCADIDECSV-GSHTCAPSGSTC-TNNVGSYVCT-CS 792 >SB_42006| Best HMM Match : EGF_2 (HMM E-Value=8.7e-05) Length = 326 Score = 48.0 bits (109), Expect = 1e-04 Identities = 52/178 (29%), Positives = 68/178 (38%), Gaps = 37/178 (20%) Query: 1518 MLSICPPYSKCVTSWD----SSTCTCEAGRV-----GP---QCV---------SACELGP 1556 +LS+C PY++C D + TC C V GP +C S C+ G Sbjct: 50 VLSLCDPYTQCFGHGDYNAATQTCKCYTAAVINVHWGPYTGECCESIGCTNPNSTCKHGA 109 Query: 1557 CG--AARCVPDQTP-KGYSC----ACEPGYTLTTSGCIESG-KEECPGGWWGGSACGPCA 1608 C C QT G +C AC P C +S + EC G W G C Sbjct: 110 CAIDGTSCERCQTGWTGANCDNVTACFPWLACAHGRCTKSRFRCECDPG-WHGDLCDRAM 168 Query: 1609 CDVTRGYHPHCNKENGKCHCKENHYKPE------GTAECLPCQCYAAGSENSSCEAAT 1660 C+V + C + KC C N+Y PE T LP +A S N+ A T Sbjct: 169 CNVPCHFGA-CPHDPNKCECYSNYYSPETGCDRLATPASLPVGAHALRSGNALSHACT 225 >SB_21404| Best HMM Match : VWA (HMM E-Value=8.1e-27) Length = 267 Score = 48.0 bits (109), Expect = 1e-04 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + CSS+PC NGA C Y C+C H GK+C Sbjct: 38 CTDDVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 76 Score = 41.5 bits (93), Expect = 0.009 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 2/36 (5%) Query: 1317 CSSAPCYNGAECSDL--WDTYICDCKEGHTGKDCAD 1350 C S PC NG CS + Y C C G+TGK+C D Sbjct: 5 CLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTD 40 Score = 35.9 bits (79), Expect = 0.47 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%) Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093 PI + +TC C G+TG NC + + S S C++G+ C+ ++ G C+ CS Sbjct: 18 PISSGSDYTCACAAGYTGKNCTDDVDECS------SSPCQNGASCI-KKVGRYFCE-CS 68 Score = 32.7 bits (71), Expect = 4.4 Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 8/69 (11%) Query: 1517 CMLSICPPYSKC--VTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570 C+ C C ++S TC C AG G C V C PC A C+ + Sbjct: 5 CLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTDDVDECSSSPCQNGASCI--KKVGR 62 Query: 1571 YSCACEPGY 1579 Y C C + Sbjct: 63 YFCECSTAH 71 >SB_41690| Best HMM Match : DSL (HMM E-Value=0) Length = 2798 Score = 47.6 bits (108), Expect = 1e-04 Identities = 41/164 (25%), Positives = 61/164 (37%), Gaps = 13/164 (7%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G + C W+G + C ++ H C+ GK HC + Y TA C P Sbjct: 1059 TGSKICHSNWYGENCTVYCKAQLSDHQHYICDNTTGKKHCLTSWYGENCTAYCTPRN--- 1115 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWP 1708 + + SC TG C G G C + Y P++G YD C S +G Sbjct: 1116 DSTGHFSCNETTGSKDCHDGWYGGTC----SIYC--LPHNGSSGHYD-CDAS-SGRKTCH 1167 Query: 1709 RTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMF--NCTT 1750 +G+ C + C+ T D++ NCTT Sbjct: 1168 VDWYGINCTVFCSKPRDSKDHYYCNVTNGEKVCTEDLYGRNCTT 1211 Score = 47.2 bits (107), Expect = 2e-04 Identities = 43/173 (24%), Positives = 63/173 (36%), Gaps = 18/173 (10%) Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGY 1579 +C Y C+ + DSS +C A G + A G C+P G+ Y Sbjct: 515 LCDTY--CIPTIDSSGHYSCNA-TTGEKICHAGWYGRLCDTYCIPTNDSSGH-------Y 564 Query: 1580 TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTA 1639 T T+ +G++ C GW+G C H CN G+ C Y Sbjct: 565 TCNTT----TGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNASTGEMICHAGWYGNLCDI 620 Query: 1640 ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692 C+P S + SC TG+ C G G CD +++ + C V Sbjct: 621 YCIPTD---DSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDISGHYSCNV 670 Score = 46.8 bits (106), Expect = 3e-04 Identities = 45/158 (28%), Positives = 60/158 (37%), Gaps = 20/158 (12%) Query: 1520 SICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG-YSCACEP 1577 ++C Y C+++ DSS TC A G + A G C+P G YSC Sbjct: 310 NLCDTY--CISTNDSSGHYTCNA-TTGEKICHAGWYGRLCDTYCIPTNDSSGHYSC---- 362 Query: 1578 GYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEG 1637 +TT G++ C GW+G C H CN G+ C Y Sbjct: 363 --NVTT------GEKICHAGWYGNLCDIYCIPTNDSSGHYSCNTTTGEKICHAGWYGNLC 414 Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 C+P S + SC TG+ C G GR CD Sbjct: 415 DIYCIPTNDI---SGHYSCNVTTGEKICHAGWYGRLCD 449 Score = 45.6 bits (103), Expect = 6e-04 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 3/89 (3%) Query: 1587 IESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQC 1646 + +G++ C GW+G C H CN G+ C Y C+P Sbjct: 772 VTTGEKICHAGWYGNLCDIYCIPTNDSSGHYSCNATTGEKICHAGWYGRLCDIYCIPTN- 830 Query: 1647 YAAGSENSSCEAATGQCHCRPGVIGRACD 1675 S + SC A+TG+ C G GR CD Sbjct: 831 --DSSGHYSCNASTGEMICHAGWYGRLCD 857 Score = 45.6 bits (103), Expect = 6e-04 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G++ C GW+G C H CN G+ C Y C+P Sbjct: 808 TGEKICHAGWYGRLCDIYCIPTNDSSGHYSCNASTGEMICHAGWYGRLCDTYCIPTN--- 864 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACD 1675 S + SC A+TG+ C G GR CD Sbjct: 865 DSSGHYSCNASTGEMICHAGWYGRLCD 891 Score = 42.7 bits (96), Expect = 0.004 Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 14/94 (14%) Query: 1586 CIESGKEECPGGWWG---GSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECL 1642 C G + C GW+G G C P D H CN+ G+ C ++ + GT Sbjct: 230 CDSKGNKVCRRGWYGPLNGCLCRPRNSD---SGHYTCNRTTGEKICLKSWF---GTL--- 280 Query: 1643 PCQCYAAGSE-NSSCEAATGQCHCRPGVIGRACD 1675 C Y S+ N SC A TG+ C G G CD Sbjct: 281 -CTIYCDESKGNYSCNATTGEKICHAGWYGNLCD 313 Score = 42.7 bits (96), Expect = 0.004 Identities = 26/106 (24%), Positives = 39/106 (36%), Gaps = 3/106 (2%) Query: 1587 IESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQC 1646 + +G++ C GW+G C H CN G+ C Y C+P Sbjct: 670 VTTGEKICHAGWYGNLCDIYCIPTNDSSGHYSCNATTGEKICHAGWYGNLCDIYCIPTN- 728 Query: 1647 YAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692 S + SC TG+ C G G CD +++ + C V Sbjct: 729 --DSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDISGHYSCNV 772 Score = 41.9 bits (94), Expect = 0.007 Identities = 43/157 (27%), Positives = 57/157 (36%), Gaps = 20/157 (12%) Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG-YSCACEPG 1578 +C Y C+ + DSS +C A G + A G C+P G YSC Sbjct: 447 LCDIY--CIPTNDSSGHYSCNA-TTGEKICHAGWYGNLCDIYCIPTNDSSGHYSC----- 498 Query: 1579 YTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638 TT G++ C GW G C + H CN G+ C Y Sbjct: 499 -NATT------GEKVCHVGWHGKLCDTYCIPTIDSSGHYSCNATTGEKICHAGWYGRLCD 551 Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 C+P S + +C TG+ C G GR CD Sbjct: 552 TYCIPTN---DSSGHYTCNTTTGEKICHAGWYGRLCD 585 Score = 41.5 bits (93), Expect = 0.009 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 3/87 (3%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G++ C GW+G C H CN G+ C Y C+P Sbjct: 298 TGEKICHAGWYGNLCDTYCISTNDSSGHYTCNATTGEKICHAGWYGRLCDTYCIPTN--- 354 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACD 1675 S + SC TG+ C G G CD Sbjct: 355 DSSGHYSCNVTTGEKICHAGWYGNLCD 381 Score = 41.5 bits (93), Expect = 0.009 Identities = 26/104 (25%), Positives = 38/104 (36%), Gaps = 3/104 (2%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G++ C GW+G C H CN G+ C Y C+P Sbjct: 332 TGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNVTTGEKICHAGWYGNLCDIYCIPTN--- 388 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692 S + SC TG+ C G G CD +++ + C V Sbjct: 389 DSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDISGHYSCNV 432 Score = 39.9 bits (89), Expect = 0.029 Identities = 41/157 (26%), Positives = 52/157 (33%), Gaps = 20/157 (12%) Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG-YSCACEPG 1578 +C Y C+ + DSS TC G + A G C+P G YSC G Sbjct: 549 LCDTY--CIPTNDSSGHYTCNT-TTGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNASTG 605 Query: 1579 YTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638 + C GW+G C H CN G+ C Y Sbjct: 606 EMI------------CHAGWYGNLCDIYCIPTDDSSGHYSCNTTTGEKICHAGWYGNLCD 653 Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 C+P S + SC TG+ C G G CD Sbjct: 654 IYCIPTNDI---SGHYSCNVTTGEKICHAGWYGNLCD 687 Score = 39.1 bits (87), Expect = 0.050 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 3/87 (3%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G++ C GW+G C H CN G+ C Y C+P Sbjct: 706 TGEKICHAGWYGNLCDIYCIPTNDSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDI- 764 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACD 1675 S + SC TG+ C G G CD Sbjct: 765 --SGHYSCNVTTGEKICHAGWYGNLCD 789 Score = 39.1 bits (87), Expect = 0.050 Identities = 23/101 (22%), Positives = 39/101 (38%), Gaps = 2/101 (1%) Query: 1586 CIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ 1645 C + G + C W+G + C + + C+ G C + Y E C+P Sbjct: 2309 CDDKGNKICLSNWYGLACNRFCKAENSTLRSYTCDNTTGLKICSTHWYGSECHTYCIPRA 2368 Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686 + G +C TG C PG G C + ++ + + P Sbjct: 2369 SHLEGY--FTCNETTGTRICIPGWTGNNCTSSKHSQSSIFP 2407 Score = 38.3 bits (85), Expect = 0.088 Identities = 22/102 (21%), Positives = 38/102 (37%), Gaps = 3/102 (2%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G + C W+G + C + + C+ G C N Y T + C+ Sbjct: 1025 TGSKLCHPDWFGENCTVHCKAQSSDNQNYSCDNATGSKICHSNWYGENCT---VYCKAQL 1081 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 + ++ C+ TG+ HC G C A + T + C Sbjct: 1082 SDHQHYICDNTTGKKHCLTSWYGENCTAYCTPRNDSTGHFSC 1123 Score = 37.9 bits (84), Expect = 0.12 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 6/104 (5%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G++ C W+G + C CD ++G + CN G+ C Y C+ Sbjct: 267 TGEKICLKSWFG-TLC-TIYCDESKGNYS-CNATTGEKICHAGWYGNLCDTYCISTN--- 320 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692 S + +C A TG+ C G GR CD + + + C V Sbjct: 321 DSSGHYTCNATTGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNV 364 Score = 37.5 bits (83), Expect = 0.15 Identities = 39/153 (25%), Positives = 57/153 (37%), Gaps = 13/153 (8%) Query: 1528 CVTSWDSSTCT--CEA--GRVGPQCVSACELGPCGAARCVPDQTPKGYSCAC-EPGYTLT 1582 C+ +W C+ CE + GP C+ G C+P+ S C E G Sbjct: 2012 CLPNWYGVNCSKYCEEKDDKFGPY---RCD-NSTGEKICLPNWYGVNCSKYCKEKGDNSG 2067 Query: 1583 TSGCIES-GKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 C S G++ C W+G + C + C+ G+ C N Y GT Sbjct: 2068 NYRCDNSTGEKICLPNWYGVNCSKYCKEKDDNSGNYRCDNSTGEKICLPNWY---GTNCI 2124 Query: 1642 LPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C+ S N C+ +TG+ C P G C Sbjct: 2125 KYCKEKGDNSGNYRCDNSTGEKICLPNWYGTNC 2157 Score = 37.1 bits (82), Expect = 0.20 Identities = 26/103 (25%), Positives = 39/103 (37%), Gaps = 3/103 (2%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G++ C W+G + C + C+ GK C N Y GT C+ Sbjct: 2143 TGEKICLPNWYGTNCIKYCKEKDDNSGNYRCDNSTGKKICLPNWY---GTNCIKYCKEKG 2199 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691 S N C+ +TG+ C P G C + + N CE Sbjct: 2200 DNSGNYRCDNSTGEKICLPNWYGVNCSKYCKEKDDNSGNYRCE 2242 Score = 35.1 bits (77), Expect = 0.82 Identities = 16/53 (30%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C +N Y T C Sbjct: 1467 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDNWYGGNCTTYC 1519 Score = 34.7 bits (76), Expect = 1.1 Identities = 38/163 (23%), Positives = 57/163 (34%), Gaps = 14/163 (8%) Query: 1539 CEAGRVGPQCVSACELGPCGAARC-------VPDQTPKGYSCA--CEPGYTLTTSGCIES 1589 C G C C+ G RC + Q G +C+ CE S Sbjct: 1948 CHKNWYGKNCRKHCQTSTRGNYRCDNVTGDKICTQKWYGENCSVFCEQNAGSHYKCNNGS 2007 Query: 1590 GKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 GK+ C W+G + C + + P+ C+ G+ C N Y G C+ Sbjct: 2008 GKKICLPNWYGVNCSKYCE-EKDDKFGPYRCDNSTGEKICLPNWY---GVNCSKYCKEKG 2063 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691 S N C+ +TG+ C P G C + + N C+ Sbjct: 2064 DNSGNYRCDNSTGEKICLPNWYGVNCSKYCKEKDDNSGNYRCD 2106 Score = 33.9 bits (74), Expect = 1.9 Identities = 30/120 (25%), Positives = 44/120 (36%), Gaps = 8/120 (6%) Query: 1528 CVTSWDSSTCT--CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSG 1585 C+ W CT C++ G C G G C+ D G +C + + G Sbjct: 1540 CLDDWYGGNCTTYCKSSN-GSDGHYYCN-GTNGERICLDDDDWYGGNCTTYCKSSNGSDG 1597 Query: 1586 ---CI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 C +G+ C W+GG+ C H CN NG+ C ++ Y T C Sbjct: 1598 HYYCNGTNGERICLDDWYGGNCTTYCKSSNGSDGHYCCNGTNGERICLDDWYGGNCTTYC 1657 Score = 33.9 bits (74), Expect = 1.9 Identities = 35/146 (23%), Positives = 49/146 (33%), Gaps = 11/146 (7%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +GK+ C W+G + C + C+ G+ C N Y G C+ Sbjct: 2177 TGKKICLPNWYGTNCIKYCKEKGDNSGNYRCDNSTGEKICLPNWY---GVNCSKYCKEKD 2233 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWP 1708 S N CE +TG+ C P G C E NSG + C S + P Sbjct: 2234 DNSGNYRCENSTGEKICLPNWYGVNCSKYCK---EKDDNSG----HYRCENSTGEKICLP 2286 Query: 1709 RTKFGVETITDCPPGSSGRATRTCDE 1734 +GV C CD+ Sbjct: 2287 NW-YGVNCSQHCKKKDDNSGHYKCDD 2311 Score = 33.5 bits (73), Expect = 2.5 Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 5/87 (5%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G+ C W+GG+ C H +CN NG+ C ++ Y T C + Sbjct: 1433 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYCKS----S 1488 Query: 1649 AGSE-NSSCEAATGQCHCRPGVIGRAC 1674 GS+ + C G+ C G C Sbjct: 1489 NGSDGHYYCNGTNGERICLDNWYGGNC 1515 Score = 33.5 bits (73), Expect = 2.5 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1501 NGERICLDNWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1553 Score = 33.5 bits (73), Expect = 2.5 Identities = 26/116 (22%), Positives = 39/116 (33%), Gaps = 2/116 (1%) Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGY-TLTTSGC 1586 C+ W CT C G G C+ D + C+ + C Sbjct: 1610 CLDDWYGGNCTTYCKSSNGSDGHYCCNGTNGERICLDDWYGGNCTTYCKSSNGSYGHYYC 1669 Query: 1587 I-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1670 NGTNGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1725 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1229 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1281 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1263 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1315 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1297 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1349 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1331 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1383 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1365 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1417 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1399 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1451 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1707 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1759 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1741 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1793 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1775 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1827 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1809 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1861 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/53 (28%), Positives = 23/53 (43%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641 +G+ C W+GG+ C H +CN NG+ C ++ Y T C Sbjct: 1843 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1895 Score = 33.1 bits (72), Expect = 3.3 Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 5/86 (5%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 +G+ C W+GG+ C + G + +C ++GK C ++ + C P Sbjct: 1877 NGERICLDDWYGGNCT--TYCKSSNGSYYYCKHDSGKRVCLDDWHGERCNVYCKPRN--- 1931 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRAC 1674 + C+ TG+ C G+ C Sbjct: 1932 NSEGHYICDIMTGEKVCHKNWYGKNC 1957 Score = 32.7 bits (71), Expect = 4.4 Identities = 40/182 (21%), Positives = 61/182 (33%), Gaps = 25/182 (13%) Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGY 1579 +C Y C+ + DSS +C A G A G + C P G+ C+P Sbjct: 889 LCDTY--CIPTNDSSGHYSCNAS-TGEMICHAHWYGESCSTNCSPQNNSLGHF-ECDP-- 942 Query: 1580 TLTTSGCIESGKEECPGGWWGGSACGPCA--------CD--VTRGYHPHCNKENGKCHCK 1629 +SG + C GW+G C CD + R Y H Sbjct: 943 --------QSGIKICHSGWFGPICSVHCKETNEKQYKCDTGLERRYATSLGLGRIVRHFA 994 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689 +G + Q ++ ++ +C+ TG C P G C A + N Sbjct: 995 RQETTAQGITFVIKKQALSSDHQHYNCDNTTGSKLCHPDWFGENCTVHCKAQSSDNQNYS 1054 Query: 1690 CE 1691 C+ Sbjct: 1055 CD 1056 Score = 32.7 bits (71), Expect = 4.4 Identities = 46/207 (22%), Positives = 70/207 (33%), Gaps = 13/207 (6%) Query: 1491 IGTAQSLLNRPTVRENVRDGCQS--RADCMLSICPPYSKCVTSWDSSTCT--CEAGRVGP 1546 I T + + ++ +N R CQ+ R + C W C+ CE G Sbjct: 1941 IMTGEKVCHKNWYGKNCRKHCQTSTRGNYRCDNVTGDKICTQKWYGENCSVFCEQN-AGS 1999 Query: 1547 QCVSACELGPCGAARCVPDQTPKGYSCACEP-GYTLTTSGCIES-GKEECPGGWWGGSAC 1604 C G G C+P+ S CE C S G++ C W+G + Sbjct: 2000 HY--KCNNGS-GKKICLPNWYGVNCSKYCEEKDDKFGPYRCDNSTGEKICLPNWYGVNCS 2056 Query: 1605 GPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCH 1664 C + C+ G+ C N Y G C+ S N C+ +TG+ Sbjct: 2057 KYCKEKGDNSGNYRCDNSTGEKICLPNWY---GVNCSKYCKEKDDNSGNYRCDNSTGEKI 2113 Query: 1665 CRPGVIGRACDACANAYAEVTPNSGCE 1691 C P G C + + N C+ Sbjct: 2114 CLPNWYGTNCIKYCKEKGDNSGNYRCD 2140 >SB_35429| Best HMM Match : Laminin_EGF (HMM E-Value=5.3e-17) Length = 218 Score = 47.6 bits (108), Expect = 1e-04 Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 9/109 (8%) Query: 1625 KCHCKENHYKP-EGTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRACDACANA-Y 1681 +C KP G ++C C+C E C+ TG+C +C G C+ CA+ Y Sbjct: 1 RCAPGYTRVKPGPGFSKCTRCKCNRHSLE---CDPETGKCINCDHNTAGDRCEKCASGFY 57 Query: 1682 AEVTPNSGCEVVYDGCPRSFAGGVWWPRTKF---GVETITDCPPGSSGR 1727 + T + + CP + A + P + G T T C PG +GR Sbjct: 58 GDATQGTPVDCKPCSCPLTIASNQFSPTCRIDSDGAPTCTACRPGYTGR 106 >SB_1249| Best HMM Match : Cadherin (HMM E-Value=0.0083) Length = 106 Score = 47.6 bits (108), Expect = 1e-04 Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIR 228 +++ I A D D G+N + Y++ GG++ +F+++S +G + + LD E SY L+I Sbjct: 8 LLSSIAAVDPDAGSNGQLTYSMSGGDS--RFTLNSATGRLQISPAGLDRELKDSYDLIIN 65 Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 D GSP + + + N + N+N +LF Sbjct: 66 VTDNGSPPNTRSQRSNNNNNNNNNNNNNNNITLF 99 Score = 42.3 bits (95), Expect = 0.005 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 7/70 (10%) Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVT 337 + A D D G N +LTY+M+ D T++ +G + S LDRE + Y L++ Sbjct: 12 IAAVDPDAGSNGQLTYSMSGGDSR------FTLNSATGRLQISPAGLDRELKDSYDLIIN 65 Query: 338 ATDGGDPPRS 347 TD G PP + Sbjct: 66 VTDNGSPPNT 75 Score = 41.9 bits (94), Expect = 0.007 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 12/78 (15%) Query: 485 GTTVLV--VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDR 541 G TVL+ ++A D D G N Q+TYS+S D +F +N TG + + LDR Sbjct: 4 GGTVLLSSIAAVDPDAGSNGQLTYSMSG---------GDSRFTLNSATGRLQISPAGLDR 54 Query: 542 ETMSGYLLTVTARDGGVP 559 E Y L + D G P Sbjct: 55 ELKDSYDLIINVTDNGSP 72 Score = 41.5 bits (93), Expect = 0.009 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 4/70 (5%) Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAV 658 +S + A D D G NG++ Y + D F ++ A+G ++ + A LDRE ++DL Sbjct: 9 LSSIAAVDPDAGSNGQLTYSMSGGD---SRFTLNSATGRLQISPAGLDRELKDSYDLIIN 65 Query: 659 AIDGGTPPQS 668 D G+PP + Sbjct: 66 VTDNGSPPNT 75 Score = 32.7 bits (71), Expect = 4.4 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 9/71 (12%) Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + I A DPD G N + YS+ GGD + F+L + G + ++ LD E + Y+L Sbjct: 9 LSSIAAVDPDAGSNGQLTYSMSGGD--SRFTLNSATGRLQ---ISPAGLDREL-KDSYDL 62 Query: 766 VIRA---ASPP 773 +I SPP Sbjct: 63 IINVTDNGSPP 73 >SB_9975| Best HMM Match : 7tm_2 (HMM E-Value=1.9e-38) Length = 1101 Score = 47.6 bits (108), Expect = 1e-04 Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 14/121 (11%) Query: 2204 WSTLRGSGEWSRVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVL--VDEVDVEFIPEP 2261 WS RG+ WS GC D D L C C+HL+ FA+L V E ++ E Sbjct: 433 WSLNRGN--WSSSGCKMTSDPD-------ERLAQCECDHLTNFAILMQVHEFKIDRAHEK 483 Query: 2262 SLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALK 2321 +L + +Y ISL L + A + A+ SIHK+L+ ++ +A++++L + Sbjct: 484 AL--QLITYVGCGISLFGLALTLATFLSLE-TLASERTSIHKNLVVAIGLAQIIFLAGID 540 Query: 2322 A 2322 A Sbjct: 541 A 541 >SB_46889| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 754 Score = 47.2 bits (107), Expect = 2e-04 Identities = 39/134 (29%), Positives = 50/134 (37%), Gaps = 13/134 (9%) Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVP 1564 D C++ D C S C CV + +CTC AG G C + C PC Sbjct: 214 DKCENNDDECKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCKTDIDECAGNPCANGGTCK 273 Query: 1565 DQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC--NKE 1622 D G++C C GY+ +T C E +EC G A G D G+ C Sbjct: 274 DGI-NGFTCECPVGYSGST--C-EIDIDECAG---NPCANGGTCKDGINGFTCECPVGYS 326 Query: 1623 NGKCHCKENHYKPE 1636 C Y PE Sbjct: 327 GSTCEIGVKCYNPE 340 Score = 45.2 bits (102), Expect = 8e-04 Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 7/64 (10%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362 C C S+PC NG C D + Y C C G TGK+C + G P GG DG Sbjct: 216 CENNDDECKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCKTDIDECAGNPCANGGTCKDG 275 Query: 1363 MLSF 1366 + F Sbjct: 276 INGF 279 Score = 38.7 bits (86), Expect = 0.066 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 7/64 (10%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362 C C+ PC NG C D + + C+C G++G C + G P GG DG Sbjct: 254 CKTDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTCEIDIDECAGNPCANGGTCKDG 313 Query: 1363 MLSF 1366 + F Sbjct: 314 INGF 317 Score = 38.7 bits (86), Expect = 0.066 Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 10/72 (13%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + FTC+CP G++G CE + + + G+ C +G C + GI C Y Sbjct: 276 INGFTCECPVGYSGSTCEIDIDECA------GNPCANGGTC----KDGINGFTCECPVGY 325 Query: 1099 TTAVCELRARSF 1110 + + CE+ + + Sbjct: 326 SGSTCEIGVKCY 337 Score = 37.5 bits (83), Expect = 0.15 Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+ PC NG C D + + C+C G++G C Sbjct: 292 CEIDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTC 330 Score = 36.3 bits (80), Expect = 0.35 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + ++C C GFTG NC+T + + + G+ C +G C + GI C Y Sbjct: 238 INRYSCTCVAGFTGKNCKTDIDECA------GNPCANGGTC----KDGINGFTCECPVGY 287 Query: 1099 TTAVCEL 1105 + + CE+ Sbjct: 288 SGSTCEI 294 Score = 31.9 bits (69), Expect = 7.6 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 10/61 (16%) Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103 C CP GF+G CE C+ S C++G CV GI C+ A +T C Sbjct: 205 CHCPAGFSGDKCEN--NDDECK----SSPCKNGGTCV----DGINRYSCTCVAGFTGKNC 254 Query: 1104 E 1104 + Sbjct: 255 K 255 >SB_11569| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 488 Score = 47.2 bits (107), Expect = 2e-04 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 1281 FVGCISDFYIDHKFI---DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYIC 1337 FVGC+++ ++ + L+ VA G + G S+C PC NG C + WD+Y C Sbjct: 249 FVGCMNNIKLNGALVRPRKLSKEVA--GAVIGRCSITSKCFPNPCQNGGACKESWDSYTC 306 Query: 1338 DCK 1340 DC+ Sbjct: 307 DCQ 309 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/44 (31%), Positives = 25/44 (56%) Query: 1181 GKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGA 1224 GK + V N+ D WHTV++ R++ + LD+ + + AG+ Sbjct: 3 GKHHVIVGENLDDNKWHTVKVARNQRSLLLTLDNKETRTNTAGS 46 Score = 32.3 bits (70), Expect = 5.8 Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 1482 FEGCIQDVRIGTAQSLLNRPT--VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTC 1539 F GC+ ++++ A + + V V C + C + C C SWDS TC C Sbjct: 249 FVGCMNNIKLNGALVRPRKLSKEVAGAVIGRCSITSKCFPNPCQNGGACKESWDSYTCDC 308 Query: 1540 E 1540 + Sbjct: 309 Q 309 >SB_26778| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1050 Score = 47.2 bits (107), Expect = 2e-04 Identities = 39/153 (25%), Positives = 50/153 (32%), Gaps = 4/153 (2%) Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCI 1587 C W CT C G GA C P+ + C+P T Sbjct: 565 CHKDWYGDLCTTFCKNKDSSEHYTCN-GTTGARICFPNWYGVNCTRFCKPDNESTFFCDK 623 Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647 +G C GW+G + C H C K +G C EN Y G A C+ Sbjct: 624 STGTRVCNAGWYGINCTTQCVGRNDSFGHYTCQKISGAKICHENWY---GQACTTFCEAR 680 Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 + + SC GQ C G CD N+ Sbjct: 681 NDSTGHYSCNLTNGQKVCHRDWYGPFCDVNCNS 713 Score = 38.7 bits (86), Expect = 0.066 Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 7/121 (5%) Query: 1558 GAARCVPDQTPKGYSCACEPGYTLTTSG---CIESGKEECPGGWWGGSACGPCACDVTRG 1614 G+ C PD + C P + T++G C+ +G + C GW+G + C Sbjct: 128 GSRLCHPDWYGSYCTIYCSPKNS-TSAGYYTCLSTGSKRCISGWYGQNCTTYCVPQNDEF 186 Query: 1615 YHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 + C+ E K C + Y C P + G + C+ TGQ C P C Sbjct: 187 ANYTCSDEGIKI-CANDWYNANCNVYCKPHRDDFIG--HFDCKNQTGQKVCMPNWYNDNC 243 Query: 1675 D 1675 + Sbjct: 244 N 244 Score = 37.9 bits (84), Expect = 0.12 Identities = 24/92 (26%), Positives = 33/92 (35%), Gaps = 6/92 (6%) Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 SG + C W+G + C H CN NG+ C + Y P C Sbjct: 659 SGAKICHENWYGQACTTFCEARNDSTGHYSCNLTNGQKVCHRDWYGPFCDVNC------N 712 Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 + S + +C TG C G CD N+ Sbjct: 713 SNSSHFTCNKTTGARVCHSNWYGTYCDVYCNS 744 Score = 36.3 bits (80), Expect = 0.35 Identities = 36/164 (21%), Positives = 56/164 (34%), Gaps = 13/164 (7%) Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647 ++G +EC W+G C H C+ G C Y P T C+P Sbjct: 323 KTGLKECFNHWYGPDCTTNCTPRNDSFGHYECDSSTGAVVCHSGWYGPTCTVNCIPRN-- 380 Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWW 1707 + +C G C G C+ ++ +SG + C R+ +G Sbjct: 381 -DSGGHYTCNETDGAKICDKHWYGTHCNVFCR---DMNDSSG----HYFCNRT-SGAKIC 431 Query: 1708 PRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMF--NCT 1749 +GV C P + R +CD D + + NCT Sbjct: 432 RNDWYGVNCTEYCTPRNKVRGHYSCDMATGAKICDSNWYGLNCT 475 Score = 33.1 bits (72), Expect = 3.3 Identities = 27/108 (25%), Positives = 42/108 (38%), Gaps = 6/108 (5%) Query: 1570 GYSCACEPGYTLTTSG---CIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 G +C YT +G C+ G++ C ++G C H C+++ G Sbjct: 71 GRACDVYCSYTDDINGHYYCLNDGQQACLNDYYGTLCKTYCYPHNDSTGHYTCHQDTGSR 130 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C + Y T C P +AG +C +TG C G G+ C Sbjct: 131 LCHPDWYGSYCTIYCSPKNSTSAG--YYTC-LSTGSKRCISGWYGQNC 175 Score = 32.7 bits (71), Expect = 4.4 Identities = 17/56 (30%), Positives = 23/56 (41%), Gaps = 3/56 (5%) Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 CN + G C + Y P+ T C P E C+++TG C G G C Sbjct: 320 CNNKTGLKECFNHWYGPDCTTNCTPRNDSFGHYE---CDSSTGAVVCHSGWYGPTC 372 >SB_47530| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 939 Score = 46.8 bits (106), Expect = 3e-04 Identities = 20/47 (42%), Positives = 23/47 (48%) Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 L GC C S PC NG C DL +Y CDC +G G +C G Sbjct: 177 LYGCVADGYECLSTPCLNGGTCVDLVASYRCDCIKGFNGTNCQYKLG 223 >SB_44915| Best HMM Match : VWA (HMM E-Value=0) Length = 541 Score = 46.8 bits (106), Expect = 3e-04 Identities = 17/39 (43%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C CSS+PC NGA C Y C+C H GK+C Sbjct: 298 CTADVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 336 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/32 (50%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSS+PC NGA C Y C+C H GK+C Sbjct: 44 CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 75 Score = 39.5 bits (88), Expect = 0.038 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348 L G + C S PC NG CS + Y C C G+TGK+C Sbjct: 255 LEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNC 298 Score = 36.3 bits (80), Expect = 0.35 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%) Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093 PI + +TC C G+TG NC + + S S C++G+ C+ ++ G C+ CS Sbjct: 278 PISSGSDYTCACAAGYTGKNCTADVDECS------SSPCQNGASCI-KKVGRYFCE-CS 328 Score = 33.1 bits (72), Expect = 3.3 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 10/86 (11%) Query: 1501 PTVRENVRDGCQSRAD-CMLSICPPYSKC--VTSWDSSTCTCEAGRVGPQC---VSACEL 1554 P++ E + +G + D C+ C C ++S TC C AG G C V C Sbjct: 249 PSLPE-ILEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTADVDECSS 307 Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGY 1579 PC A C+ + Y C C + Sbjct: 308 SPCQNGASCI--KKVGRYFCECSTAH 331 >SB_32721| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 637 Score = 46.8 bits (106), Expect = 3e-04 Identities = 52/183 (28%), Positives = 67/183 (36%), Gaps = 37/183 (20%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAAR-----CVPD 1565 C++ A C + C C D CTC +G G C E G A + C+PD Sbjct: 432 CEAEAQCKHAPCHNGGTCTELHDGFQCTCSSGYRGNTCKGDAEYGIEAAQKRTSEVCLPD 491 Query: 1566 QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGS-------ACGPCACDVT-----R 1613 G SC Y + + K CP G+ G S A PC D T Sbjct: 492 PCHNGGSC-----YIVD-----DKFKCFCPPGFKGDSCERNDFCASDPCLNDGTCKETPA 541 Query: 1614 GYHPHCNKENGKCHCK-ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGR 1672 GY C E +C+ ENH KP PC+ E +CHC+ G G Sbjct: 542 GYRCMCRPEFRGKNCETENHCKPVN-----PCENNGLCIETQD----NYRCHCKLGYKGF 592 Query: 1673 ACD 1675 C+ Sbjct: 593 NCE 595 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/36 (44%), Positives = 22/36 (61%) Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 K++RC PC NG C+D+ + Y C C G+ G DC Sbjct: 397 KKARCHPNPCQNGGSCTDVRNGYECTCLTGYKGHDC 432 Score = 45.6 bits (103), Expect = 6e-04 Identities = 15/37 (40%), Positives = 22/37 (59%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E ++C APC+NG C++L D + C C G+ G C Sbjct: 433 EAEAQCKHAPCHNGGTCTELHDGFQCTCSSGYRGNTC 469 Score = 42.3 bits (95), Expect = 0.005 Identities = 41/167 (24%), Positives = 58/167 (34%), Gaps = 12/167 (7%) Query: 1514 RADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKG 1570 +A C + C C + CTC G G C + C+ PC C + G Sbjct: 398 KARCHPNPCQNGGSCTDVRNGYECTCLTGYKGHDCEAEAQCKHAPCHNGGTCT--ELHDG 455 Query: 1571 YSCACEPGYT-LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 + C C GY T G E G E C P C G + + KC C Sbjct: 456 FQCTCSSGYRGNTCKGDAEYGIEAAQKR--TSEVCLPDPCH--NGGSCYIVDDKFKCFCP 511 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRACD 1675 +K + C ++ + E G +C CRP G+ C+ Sbjct: 512 PG-FKGDSCERNDFCASDPCLNDGTCKETPAGYRCMCRPEFRGKNCE 557 Score = 35.5 bits (78), Expect = 0.62 Identities = 50/182 (27%), Positives = 58/182 (31%), Gaps = 25/182 (13%) Query: 1549 VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIES-GKEEC-PGGWWGGSACG 1605 V CE PC +C C C PGY T C + K C P G +C Sbjct: 356 VYGCEPNPCLHDGKCHRTHHRTRIRCVCMPGY--TGQRCQRALKKARCHPNPCQNGGSC- 412 Query: 1606 PCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCH 1664 DV GY C C + E A+C C+ G + E G QC Sbjct: 413 ---TDVRNGY--ECT-----CLTGYKGHDCEAEAQCKHAPCHNGG---TCTELHDGFQCT 459 Query: 1665 CRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGS 1724 C G G C A E EV P G + KF CPPG Sbjct: 460 CSSGYRGNTCKGDAEYGIEAAQKRTSEVCLPD-PCHNGGSCYIVDDKFK----CFCPPGF 514 Query: 1725 SG 1726 G Sbjct: 515 KG 516 Score = 35.1 bits (77), Expect = 0.82 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 8/69 (11%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 T C C G+TG C+ L KA C + C++G C R G C+ Y Sbjct: 377 TRIRCVCMPGYTGQRCQRALKKARCHPNP----CQNGGSCTDVRNG----YECTCLTGYK 428 Query: 1100 TAVCELRAR 1108 CE A+ Sbjct: 429 GHDCEAEAQ 437 Score = 33.9 bits (74), Expect = 1.9 Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E+ C+S PC N C + Y C C+ GK+C Sbjct: 520 ERNDFCASDPCLNDGTCKETPAGYRCMCRPEFRGKNC 556 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Query: 1312 EKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E + C PC N C + D Y C CK G+ G +C Sbjct: 557 ETENHCKPVNPCENNGLCIETQDNYRCHCKLGYKGFNC 594 Score = 33.1 bits (72), Expect = 3.3 Identities = 15/47 (31%), Positives = 19/47 (40%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A+ G A C PC+NG C + D + C C G G C Sbjct: 473 AEYGIEAAQKRTSEVCLPDPCHNGGSCYIVDDKFKCFCPPGFKGDSC 519 >SB_29838| Best HMM Match : EGF (HMM E-Value=1.2e-15) Length = 373 Score = 46.8 bits (106), Expect = 3e-04 Identities = 18/37 (48%), Positives = 22/37 (59%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E C+S PC NGA C+D + Y C C G TGK+C Sbjct: 265 ENIDECASGPCQNGATCNDDVNKYTCSCIPGFTGKNC 301 Score = 37.9 bits (84), Expect = 0.12 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 1537 CTCEAGRVGPQC--VSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580 C C AG G +C + C GPC D K Y+C+C PG+T Sbjct: 253 CHCLAGFSGDKCENIDECASGPCQNGATCNDDVNK-YTCSCIPGFT 297 Score = 34.7 bits (76), Expect = 1.1 Identities = 13/20 (65%), Positives = 14/20 (70%) Query: 1039 VTSFTCQCPEGFTGVNCETI 1058 V +TC C GFTG NCETI Sbjct: 285 VNKYTCSCIPGFTGKNCETI 304 >SB_13163| Best HMM Match : VWA (HMM E-Value=2.3e-32) Length = 318 Score = 46.8 bits (106), Expect = 3e-04 Identities = 17/39 (43%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C CSS+PC NGA C Y C+C H GK+C Sbjct: 94 CTADVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 132 Score = 39.5 bits (88), Expect = 0.038 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348 L G + C S PC NG CS + Y C C G+TGK+C Sbjct: 51 LEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNC 94 Score = 36.3 bits (80), Expect = 0.35 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%) Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093 PI + +TC C G+TG NC + + S S C++G+ C+ ++ G C+ CS Sbjct: 74 PISSGSDYTCACAAGYTGKNCTADVDECS------SSPCQNGASCI-KKVGRYFCE-CS 124 Score = 33.1 bits (72), Expect = 3.3 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 10/86 (11%) Query: 1501 PTVRENVRDGCQSRAD-CMLSICPPYSKC--VTSWDSSTCTCEAGRVGPQC---VSACEL 1554 P++ E + +G + D C+ C C ++S TC C AG G C V C Sbjct: 45 PSLPE-ILEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTADVDECSS 103 Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGY 1579 PC A C+ + Y C C + Sbjct: 104 SPCQNGASCI--KKVGRYFCECSTAH 127 >SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 2411 Score = 46.8 bits (106), Expect = 3e-04 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 6/94 (6%) Query: 1258 LTGPLQIGGLPNIPSSFQVK---NKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKR 1314 L PL +G + ++ Q + + FVGCI DF ++ DL A L +R Sbjct: 2143 LDSPLYLG-VSQSEANLQTRVGVSTSFVGCIRDFRVEDP--DLRLRAASFDQLTVNQVRR 2199 Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C NG C+ Y C+C+ G TG C Sbjct: 2200 CGCRDGGCANGGVCTKRIKDYRCECRTGFTGSRC 2233 >SB_5993| Best HMM Match : EGF_2 (HMM E-Value=9e-14) Length = 360 Score = 46.8 bits (106), Expect = 3e-04 Identities = 38/136 (27%), Positives = 54/136 (39%), Gaps = 22/136 (16%) Query: 1539 CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGW 1598 C GR G C C C T K C C G+T C + C G+ Sbjct: 104 CPTGRFGAGCTGVCT---CHRGSICDHVTGK---CHCGLGWTGVK--C----DQVCKEGY 151 Query: 1599 WGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ--CYAAGS----E 1652 +G + CAC + G C++ +G C C Y + C P + Y AG Sbjct: 152 YGVNCEHKCAC-LNGGT---CDRVSGCCECNSGWYGDKCQYRCPPGRFGLYCAGICKCVN 207 Query: 1653 NSSCEAATGQCHCRPG 1668 SC+ +G+C+C+PG Sbjct: 208 GESCDPVSGECYCKPG 223 Score = 41.5 bits (93), Expect = 0.009 Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 10/88 (11%) Query: 1593 ECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC------LPCQC 1646 ECP G +G G C C RG C+ GKCHC + C + C+ Sbjct: 103 ECPTGRFGAGCTGVCTCH--RG--SICDHVTGKCHCGLGWTGVKCDQVCKEGYYGVNCEH 158 Query: 1647 YAAGSENSSCEAATGQCHCRPGVIGRAC 1674 A +C+ +G C C G G C Sbjct: 159 KCACLNGGTCDRVSGCCECNSGWYGDKC 186 Score = 39.1 bits (87), Expect = 0.050 Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 1644 CQCYAAGSENSSCEAATGQCHCRPGVIGRACD-ACANAYAEVTPNSGCEVVYDGCPRSFA 1702 C C+ S C+ TG+CHC G G CD C Y V C + G + Sbjct: 117 CTCH----RGSICDHVTGKCHCGLGWTGVKCDQVCKEGYYGVNCEHKCACLNGGTCDRVS 172 Query: 1703 GGVWWPRTKFGVETITDCPPGSSG 1726 G +G + CPPG G Sbjct: 173 GCCECNSGWYGDKCQYRCPPGRFG 196 Score = 38.3 bits (85), Expect = 0.088 Identities = 34/118 (28%), Positives = 47/118 (39%), Gaps = 21/118 (17%) Query: 1521 ICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580 +C + + + C C G G +C C+ G G C + CAC G T Sbjct: 116 VCTCHRGSICDHVTGKCHCGLGWTGVKCDQVCKEGYYG-VNC-------EHKCACLNGGT 167 Query: 1581 L-TTSGCIE--SG------KEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 SGC E SG + CP G +G G C C G C+ +G+C+CK Sbjct: 168 CDRVSGCCECNSGWYGDKCQYRCPPGRFGLYCAGICKC--VNG--ESCDPVSGECYCK 221 >SB_4760| Best HMM Match : EGF (HMM E-Value=8.29989e-42) Length = 240 Score = 46.8 bits (106), Expect = 3e-04 Identities = 32/126 (25%), Positives = 46/126 (36%), Gaps = 7/126 (5%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA---CELGPC-GAARCVPDQTPKGYS 1572 C + C +C + + C+C G G +C ++ C+ PC +CV + GY Sbjct: 41 CAPNPCEHDGECSVAGKNYDCSCSLGWKGEKCEASQGKCQKNPCMNGGKCVETLSGTGYE 100 Query: 1573 CACEPGYTLTTSGCIESG-KEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631 C+C GY I++ C G S G C T Y N K H Sbjct: 101 CSCPSGYRGEVCDVIDNCLSNPCQNGATCNSVAGGFTCTCTPEYRG--NSVTRKRHVTLT 158 Query: 1632 HYKPEG 1637 H G Sbjct: 159 HVTMAG 164 Score = 36.7 bits (81), Expect = 0.27 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 1540 EAGRVGPQCVSA-CELGPCGAARCVPDQTPKGYSCACEPGYT 1580 + G QCV CE PC RC+ + Y CAC+ GYT Sbjct: 194 QEGTESYQCVKKMCEPNPCQHGRCI-EVNDDDYQCACDAGYT 234 Score = 35.5 bits (78), Expect = 0.62 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSD-LWDT-YICDCKEGHTGKDC 1348 C + +C PC NG +C + L T Y C C G+ G+ C Sbjct: 72 CEASQGKCQKNPCMNGGKCVETLSGTGYECSCPSGYRGEVC 112 Score = 34.3 bits (75), Expect = 1.4 Identities = 14/37 (37%), Positives = 17/37 (45%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 C+ PC + ECS Y C C G G+ C S G Sbjct: 41 CAPNPCEHDGECSVAGKNYDCSCSLGWKGEKCEASQG 77 Score = 32.3 bits (70), Expect = 5.8 Identities = 13/35 (37%), Positives = 17/35 (48%) Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C PC +G D Y C C G+TGK+C Sbjct: 204 KKMCEPNPCQHGRCIEVNDDDYQCACDAGYTGKNC 238 >SB_46360| Best HMM Match : EGF (HMM E-Value=0) Length = 352 Score = 46.8 bits (106), Expect = 3e-04 Identities = 46/168 (27%), Positives = 56/168 (33%), Gaps = 14/168 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC + C Y C TC C G G C + CE PC A C D KGY Sbjct: 127 DCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL-KGY 185 Query: 1572 SCACEPGYTLTTSGCIESGKEEC--PGGWWGGSACGPCACDVTRGYHPHCNKENGKC--- 1626 SC+C G T + C G + C C + P C + C Sbjct: 186 SCSCPTGVTGRHCDVSICDSKPCRNNGSCVLTQSGYQCLC-ASSFTSPQCQRSIDDCEHA 244 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 HC N + C C G CE +CH +P G C Sbjct: 245 HCL-NGATCVDSDNAYKCSC-LEGYYGKHCE-LIDRCHSQPCQNGATC 289 Score = 44.0 bits (99), Expect = 0.002 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360 C C+++PC N A C+DL + + C C G+ G+ CA D T P + GG Sbjct: 7 CEANIDDCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGG 61 Score = 44.0 bits (99), Expect = 0.002 Identities = 48/189 (25%), Positives = 63/189 (33%), Gaps = 27/189 (14%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQT----PKGY 1571 DC C CV + TC C G G C + E+ CG+ C+ + T Sbjct: 51 DCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINC--SIEMDECGSYPCLNNGTCVDGRNRV 108 Query: 1572 SCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 +C C G+ T E ++C P C D T +P E C Sbjct: 109 TCTCAVGF---TGQFCEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGET----CA- 160 Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSC--EAATG-QCHCRPGVIGRACDACANAYAEVTPN 1687 P E PCQ N++C + G C C GV GR CD N Sbjct: 161 ---TPIDLCEAHPCQ------NNATCRMDPLKGYSCSCPTGVTGRHCDVSICDSKPCRNN 211 Query: 1688 SGCEVVYDG 1696 C + G Sbjct: 212 GSCVLTQSG 220 Score = 42.7 bits (96), Expect = 0.004 Identities = 46/162 (28%), Positives = 56/162 (34%), Gaps = 18/162 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 DC S C + C + C C AG G C V C PC D GY+ Sbjct: 13 DCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGGTCVDAV-SGYT 71 Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632 C C PG+T + IE +EC G + G C D C C+ N Sbjct: 72 CLCMPGFT-GINCSIE--MDEC--GSYPCLNNGTCV-DGRNRVTCTCAVGFTGQFCEVN- 124 Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 +C P C G+ A CHC PG G C Sbjct: 125 -----IDDCDPAPCQNYGTCQDL--VADFTCHCYPGFTGETC 159 Score = 42.7 bits (96), Expect = 0.004 Identities = 19/47 (40%), Positives = 22/47 (46%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A + T C C A C NGA C D + Y C C EG+ GK C Sbjct: 226 ASSFTSPQCQRSIDDCEHAHCLNGATCVDSDNAYKCSCLEGYYGKHC 272 Score = 39.5 bits (88), Expect = 0.038 Identities = 16/40 (40%), Positives = 18/40 (45%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C C APC N C DL + C C G TG+ CA Sbjct: 121 CEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCA 160 Score = 38.7 bits (86), Expect = 0.066 Identities = 16/33 (48%), Positives = 16/33 (48%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 RC S PC NGA C D C C G TG C Sbjct: 277 RCHSQPCQNGATCVDDDGVVFCKCAMGFTGTHC 309 Score = 37.9 bits (84), Expect = 0.12 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 999 DNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE-T 1057 D C P E C T + A N+ + P+ ++C CP G TG +C+ + Sbjct: 145 DFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL---KGYSCSCPTGVTGRHCDVS 201 Query: 1058 ILTKASCEVDGDGSICRSGSQCV 1080 I C +G + +SG QC+ Sbjct: 202 ICDSKPCRNNGSCVLTQSGYQCL 224 Score = 35.5 bits (78), Expect = 0.62 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 12/68 (17%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI-CRSGSQCVARREGGILCQGCSIDAA 1097 V+ +TC C GFTG+NC S E+D GS C + CV R + C C++ Sbjct: 67 VSGYTCLCMPGFTGINC-------SIEMDECGSYPCLNNGTCVDGR-NRVTCT-CAV--G 115 Query: 1098 YTTAVCEL 1105 +T CE+ Sbjct: 116 FTGQFCEV 123 Score = 35.1 bits (77), Expect = 0.82 Identities = 14/39 (35%), Positives = 17/39 (43%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC N C D + C C G TG+ C Sbjct: 83 CSIEMDECGSYPCLNNGTCVDGRNRVTCTCAVGFTGQFC 121 Score = 34.7 bits (76), Expect = 1.1 Identities = 13/33 (39%), Positives = 16/33 (48%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 C+ PC G C D Y C C G TG +C+ Sbjct: 52 CTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCS 84 Score = 33.5 bits (73), Expect = 2.5 Identities = 15/40 (37%), Positives = 17/40 (42%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDC 1348 C C + PC N A C D Y C C G TG+ C Sbjct: 159 CATPIDLCEAHPCQNNATCRMDPLKGYSCSCPTGVTGRHC 198 >SB_44887| Best HMM Match : EGF (HMM E-Value=4.1e-09) Length = 193 Score = 46.8 bits (106), Expect = 3e-04 Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 23/147 (15%) Query: 1305 GTLAGCPEKR--SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDG 1362 GTLA R C S PC +G C+ ++ Y C C +TG +C + + + Sbjct: 41 GTLAKTARLRYVQECQSEPCQHGGTCTKRFNGYECSCAPTYTGANCEKALSSDYDLTINN 100 Query: 1363 MLSFNPLLRPI-QLPWLNALSIR--TRQRD-----AFVMSIQ----LKSGL-------LH 1403 S NP I ++P L A S+ R D A S++ L+ GL L+ Sbjct: 101 RAS-NPYAATIKKIPDLTAFSVSLWVRSDDEQPGTALSYSVENSGKLQDGLVLQDFGGLN 159 Query: 1404 YSYNGETMYLPMATLSDGAWHRIEIKW 1430 N E YL + L DG WH + + W Sbjct: 160 LFINDEATYLGVDVL-DGFWHHVAVTW 185 >SB_26480| Best HMM Match : EGF (HMM E-Value=0) Length = 1772 Score = 46.8 bits (106), Expect = 3e-04 Identities = 39/140 (27%), Positives = 59/140 (42%), Gaps = 21/140 (15%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369 C + C S PC +G C+ ++ Y C C +TG +C + + + S NP Sbjct: 1146 CETEVQECQSEPCQHGGTCTKRFNGYECSCAPTYTGANCEKALSSDYDLTINNRAS-NPY 1204 Query: 1370 LRPI-QLPWLNALSIR--TRQRD-----AFVMSIQ----LKSGL-------LHYSYNGET 1410 I ++P L A S+ R D A S++ L+ GL L+ N E Sbjct: 1205 AATIKKIPDLTAFSVSLWVRSDDEQPGTALSYSVENSGKLQDGLVLQDFGGLNLFINDEA 1264 Query: 1411 MYLPMATLSDGAWHRIEIKW 1430 YL + L DG WH + + W Sbjct: 1265 TYLGVDVL-DGFWHHVAVTW 1283 Score = 45.2 bits (102), Expect = 8e-04 Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC----ADSTGPPWRFG 1359 +GTL C CS+ PC NG C D Y C C G+TGK+C + P + G Sbjct: 1104 SGTL--CQFNDDDCSAKPCRNGGSCIDNERFYTCACPAGYTGKNCETEVQECQSEPCQHG 1161 Query: 1360 GDGMLSFN 1367 G FN Sbjct: 1162 GTCTKRFN 1169 Score = 43.2 bits (97), Expect = 0.003 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC CP G+TG NCET + + E C+ G C R G CS YT A Sbjct: 1133 YTCACPAGYTGKNCETEVQECQSEP------CQHGGTCTKRFNG----YECSCAPTYTGA 1182 Query: 1102 VCE 1104 CE Sbjct: 1183 NCE 1185 Score = 42.7 bits (96), Expect = 0.004 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC C C+ + TC C AG G C V C+ PC C + GY Sbjct: 1114 DCSAKPCRNGGSCIDNERFYTCACPAGYTGKNCETEVQECQSEPCQHGGTCT--KRFNGY 1171 Query: 1572 SCACEPGYT 1580 C+C P YT Sbjct: 1172 ECSCAPTYT 1180 Score = 41.5 bits (93), Expect = 0.009 Identities = 15/36 (41%), Positives = 23/36 (63%) Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 K + C+S+PC N A+C D ++Y C+C G G +C Sbjct: 803 KVNDCASSPCNNNAKCIDTKESYRCECLPGFQGANC 838 Score = 41.1 bits (92), Expect = 0.012 Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 1502 TVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC- 1557 + R + C DC S C +KC+ + +S C C G G C V C+ PC Sbjct: 792 SARSTRLEDCGKVNDCASSPCNNNAKCIDTKESYRCECLPGFQGANCDKEVDECDKQPCF 851 Query: 1558 GAARCV 1563 GAA CV Sbjct: 852 GAATCV 857 Score = 37.9 bits (84), Expect = 0.12 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 12/91 (13%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGA----ARCVPDQTPKGY 1571 DC + C +CV +C C G GPQC + P A ++ V T Sbjct: 1645 DCSSNPCRSRGQCVDRLKGYSCNCFPGYSGPQCSTVVPCSPLDAPVYGSKSVSGNT---V 1701 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGS 1602 + +C+ GY + + S C G W G+ Sbjct: 1702 NFSCQSGYQI-----VGSSSRSCTSGQWTGT 1727 Score = 36.7 bits (81), Expect = 0.27 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 7/48 (14%) Query: 1309 GCPEK-------RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 GCP++ + CSS PC + +C D Y C+C G++G C+ Sbjct: 1631 GCPDRLVAPNVNSNDCSSNPCRSRGQCVDRLKGYSCNCFPGYSGPQCS 1678 Score = 35.9 bits (79), Expect = 0.47 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 1594 CPGGWW----GGSACGPCACDVTRGYHPH-CNKENGKCHCKENHYKPEGTAECLPCQC-- 1646 CP G + G C C D T + H N N + C ++ G A C PC+ Sbjct: 713 CPEGSYMNHEGALECKACP-DGTWTFGSHKANFTNCQAECGPGYFSATGIARCYPCKAGE 771 Query: 1647 YAAGSENSSCE 1657 Y++G N CE Sbjct: 772 YSSGERNKKCE 782 Score = 35.1 bits (77), Expect = 0.82 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 8/60 (13%) Query: 1534 SSTCTCEAGR---VGPQCV--SACELGPCGAAR-CVPDQTPKGYSCACEPGYTLTTSGCI 1587 SS+ +C +G+ P+C + C +G A+ C+ TP Y+CAC GY L + CI Sbjct: 1714 SSSRSCTSGQWTGTQPRCEDQNECSVGNHRCAQLCI--NTPGSYNCACAKGYRLDNNNCI 1771 >SB_33722| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 124 Score = 46.4 bits (105), Expect = 3e-04 Identities = 37/114 (32%), Positives = 48/114 (42%), Gaps = 16/114 (14%) Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELG--PCGA-ARCVPDQ 1566 +C L + CP + C S TC C+ G V C + C LG C A A CV + Sbjct: 4 ECALGVANCPASADCFNYDGSYTCRCKRGYTLVNKTCTDIDECALGVATCPASADCVNND 63 Query: 1567 TPKGYSCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCACDVTRGY 1615 Y+C C+PGYTL + C + G CP + G C RGY Sbjct: 64 G--SYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCFNYDGSYTCRCKRGY 115 Score = 41.9 bits (94), Expect = 0.007 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 7/87 (8%) Query: 1507 VRDGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELGPCGAA 1560 V C +C L + CP + CV + S TC C+ G V C + C LG Sbjct: 36 VNKTCTDIDECALGVATCPASADCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCP 95 Query: 1561 RCVPDQTPKG-YSCACEPGYTLTTSGC 1586 G Y+C C+ GYTL C Sbjct: 96 ASADCFNYDGSYTCRCKRGYTLVNKTC 122 >SB_22957| Best HMM Match : EGF (HMM E-Value=7e-39) Length = 201 Score = 46.4 bits (105), Expect = 3e-04 Identities = 43/173 (24%), Positives = 61/173 (35%), Gaps = 18/173 (10%) Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVS----ACELGPC-GAARCVPDQTPKGYSCACEPGY 1579 YS C+ ++ TC C G C + C+ PC C Y+CAC GY Sbjct: 2 YSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLCDPNPCQNGGVCKETFDRNNYTCACPQGY 61 Query: 1580 T-LTTSGCIESGKE-ECPGGWW---GGSACGPCACDVTRGYHP-HCNKENGKCH---CKE 1630 T +G + + C G +A C G++ C + C CK Sbjct: 62 TGWNCNGTLHPCETLNCNNGGTCQKQSNASDDYVCVCVTGFNGIRCEQNIDDCASLPCK- 120 Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPG--VIGRACDACANAY 1681 H K C C +G E C+ +C +PG + G CD Y Sbjct: 121 -HGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNGGTCDNYLGTY 172 Score = 41.1 bits (92), Expect = 0.012 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 9/76 (11%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCE-AGRVGPQC---VSACEL--GPC-GAARCV 1563 C+ D S+ + KCV ++ TC C +G GP+C ++ C++ GPC C Sbjct: 107 CEQNIDDCASLPCKHGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNGGTC- 165 Query: 1564 PDQTPKGYSCACEPGY 1579 D Y C+C+ GY Sbjct: 166 -DNYLGTYGCSCKAGY 180 Score = 41.1 bits (92), Expect = 0.012 Identities = 14/31 (45%), Positives = 19/31 (61%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 PC NG C + TY C CK G+ GK+C ++ Sbjct: 158 PCLNGGTCDNYLGTYGCSCKAGYRGKNCQEN 188 Score = 38.7 bits (86), Expect = 0.066 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354 C PC NG C + +D Y C C +G+TG +C + P Sbjct: 33 CDPNPCQNGGVCKETFDRNNYTCACPQGYTGWNCNGTLHP 72 Score = 33.5 bits (73), Expect = 2.5 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS 1077 ++TC CP+G+TG NC L +G C+ S Sbjct: 52 NYTCACPQGYTGWNCNGTLHPCETLNCNNGGTCQKQS 88 >SB_40913| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 656 Score = 46.4 bits (105), Expect = 3e-04 Identities = 18/39 (46%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C S PC NGA C+D + Y C CK G+TG C Sbjct: 364 CQQDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVC 402 Score = 44.8 bits (101), Expect = 0.001 Identities = 17/39 (43%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC NGA C+D + Y C C G+TG +C Sbjct: 326 CETDINECQSNPCLNGATCTDHVNGYTCSCALGYTGIEC 364 Score = 43.6 bits (98), Expect = 0.002 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TC+C G G +C ++ C+ PC D GY+ Sbjct: 332 ECQSNPCLNGATCTDHVNGYTCSCALGYTGIECQQDINECQSNPCLNGATCTDHV-NGYT 390 Query: 1573 CACEPGYT 1580 C+C+ GYT Sbjct: 391 CSCKLGYT 398 Score = 40.7 bits (91), Expect = 0.016 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 1315 SRCSSAPCYNGAECSDLW--DTYICDCKEGHTGKDC 1348 S C S PC +G+ C + DTY C C +G+TG+ C Sbjct: 291 SPCQSDPCLHGSRCLAAYTDDTYTCACLQGYTGRHC 326 Score = 35.5 bits (78), Expect = 0.62 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Query: 1037 YPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQC-VARREGGILCQ-- 1090 Y ++TC C +G+TG +CET + + +G+ C +G C A GI CQ Sbjct: 308 YTDDTYTCACLQGYTGRHCETDINECQSNPCLNGATCTDHVNGYTCSCALGYTGIECQQD 367 Query: 1091 --GCSIDAAYTTAVCELRARSFPVSSFLTFPGL 1121 C + A C + S L + G+ Sbjct: 368 INECQSNPCLNGATCTDHVNGYTCSCKLGYTGI 400 Score = 35.1 bits (77), Expect = 0.82 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 19/132 (14%) Query: 1550 SACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPC 1607 S C+ PC +RC+ T Y+CAC GY T C E+ EC G+ C Sbjct: 291 SPCQSDPCLHGSRCLAAYTDDTYTCACLQGY--TGRHC-ETDINECQSNPCLNGATC--- 344 Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667 D GY C C+++ EC C + T C C+ Sbjct: 345 -TDHVNGYTCSCALGYTGIECQQD------INECQSNPCLNGATCTDHVNGYT--CSCKL 395 Query: 1668 GVIGRAC--DAC 1677 G G C D+C Sbjct: 396 GYTGIVCQKDSC 407 >SB_48384| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1678 Score = 46.0 bits (104), Expect = 4e-04 Identities = 42/173 (24%), Positives = 64/173 (36%), Gaps = 20/173 (11%) Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELGP--CGAARC 1562 C +C L + CP + CV + S TC C+ G V C V+ C P C Sbjct: 930 CDDIDECGLGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCTDVNECTETPYVCSGENS 989 Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKE 1622 + + T + C+C+ GYT S + + P + R +C Sbjct: 990 ICENTDGSFKCSCKSGYTPKFSEAV----GDAPANLTSCDGKTAVHSKLVRNVIRYCVNN 1045 Query: 1623 NGK--CHCKENHYKPEGTAECLPCQC---YAAGSENSSCEAATGQ--CHCRPG 1668 +G C CK + T E + +C A ++ C G C C+PG Sbjct: 1046 DGSYTCKCKPGYTLVNNTCEDID-ECALGVATCPASADCVNNDGSYTCRCKPG 1097 Score = 41.5 bits (93), Expect = 0.009 Identities = 40/163 (24%), Positives = 58/163 (35%), Gaps = 16/163 (9%) Query: 1549 VSACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606 V+ C P C + + T + C+C+ GYT S + + P Sbjct: 880 VNECTETPYVCSGNNSICENTDGSFKCSCKSGYTPKFSEAV----GDAPANLTSCDDIDE 935 Query: 1607 CACDV-TRGYHPHCNKENGK--CHCKENHYKPEGTA----ECLPCQCYAAGSENSSCEAA 1659 C V T C +G C CK + T EC Y ENS CE Sbjct: 936 CGLGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCTDVNECTETP-YVCSGENSICENT 994 Query: 1660 TG--QCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRS 1700 G +C C+ G + +A +A A +T G V+ R+ Sbjct: 995 DGSFKCSCKSGYTPKFSEAVGDAPANLTSCDGKTAVHSKLVRN 1037 Score = 31.9 bits (69), Expect = 7.6 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 12/73 (16%) Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630 Y+C C+PGYTL + C + +EC G + C P + D N + C CK Sbjct: 1049 YTCKCKPGYTLVNNTCEDI--DECA---LGVATC-PASADCVN------NDGSYTCRCKP 1096 Query: 1631 NHYKPEGTAECLP 1643 + E +P Sbjct: 1097 GYELNNNECEAVP 1109 >SB_36058| Best HMM Match : VWA (HMM E-Value=7.4e-23) Length = 187 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/32 (50%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSS+PC NGA C Y C+C H GK+C Sbjct: 5 CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 36 >SB_28093| Best HMM Match : VWA (HMM E-Value=4.4e-33) Length = 222 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/32 (50%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSS+PC NGA C Y C+C H GK+C Sbjct: 5 CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 36 >SB_54456| Best HMM Match : EGF (HMM E-Value=2.3e-31) Length = 491 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/37 (43%), Positives = 23/37 (62%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 ++ S+C PC NGA C++ + YIC C G GK+C Sbjct: 422 DEESKCEPNPCRNGAVCTETREKYICSCTYGFMGKNC 458 Score = 42.7 bits (96), Expect = 0.004 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 5/74 (6%) Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPD 1565 D C ++ C + C ++ C + CTC G G C S CE PC A C Sbjct: 382 DRCDIQSKCFPNPCKNFATCTEHPNDYECTCHPGFHGKNCDEESKCEPNPCRNGAVCT-- 439 Query: 1566 QTPKGYSCACEPGY 1579 +T + Y C+C G+ Sbjct: 440 ETREKYICSCTYGF 453 Score = 36.3 bits (80), Expect = 0.35 Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 +S+C PC N A C++ + Y C C G GK+C + + Sbjct: 387 QSKCFPNPCKNFATCTEHPNDYECTCHPGFHGKNCDEES 425 Score = 35.9 bits (79), Expect = 0.47 Identities = 14/34 (41%), Positives = 18/34 (52%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 S C +PC NG CS + + Y C C G+ G C Sbjct: 351 SPCEVSPCRNGGTCSAVGNEYRCVCALGYKGDRC 384 >SB_39378| Best HMM Match : VWA (HMM E-Value=0) Length = 2865 Score = 45.6 bits (103), Expect = 6e-04 Identities = 16/32 (50%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSS+PC NGA C Y C+C H GK+C Sbjct: 195 CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 226 Score = 41.1 bits (92), Expect = 0.012 Identities = 17/33 (51%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 1317 CSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348 C PC NG C S L TY C C+EG GK C Sbjct: 2123 CYDMPCQNGGTCTSTLSRTYTCSCREGFAGKHC 2155 Score = 40.7 bits (91), Expect = 0.016 Identities = 15/30 (50%), Positives = 17/30 (56%) Query: 1319 SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 S PCYNG C + Y C C +G TGK C Sbjct: 1451 SNPCYNGGTCVNEEGAYSCQCSDGFTGKHC 1480 Score = 39.5 bits (88), Expect = 0.038 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348 L G + C S PC NG CS + Y C C G+TGK+C Sbjct: 406 LEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNC 449 Score = 38.7 bits (86), Expect = 0.066 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 6/66 (9%) Query: 1489 VRIGTAQSLLNR-PTVRENVRDGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGP 1546 ++ + + L+N PT++E+V S AD C+LS+C SKC S C C +G G Sbjct: 2332 IQADSMEELINFIPTIKESVL----SIADPCLLSLCKNGSKCTLSGSGFRCECASGYNGL 2387 Query: 1547 QCVSAC 1552 C + C Sbjct: 2388 LCQNVC 2393 Score = 38.3 bits (85), Expect = 0.088 Identities = 16/37 (43%), Positives = 19/37 (51%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 S C S+PC NG CS+ + C C G GK C S Sbjct: 1896 STCDSSPCLNGGFCSNTEIGFSCVCPVGFAGKTCEKS 1932 Score = 37.9 bits (84), Expect = 0.12 Identities = 22/69 (31%), Positives = 24/69 (34%), Gaps = 6/69 (8%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV--SACELGPCGAARC----VPDQTPKG 1570 C LS C C TCTC G G C C L C V TP Sbjct: 2618 CALSPCKNGGSCSGDLSGYTCTCAFGWTGVNCEIRDFCALASVNGPACFNGGVCTNTPTS 2677 Query: 1571 YSCACEPGY 1579 Y+C C G+ Sbjct: 2678 YTCTCARGF 2686 Score = 36.7 bits (81), Expect = 0.27 Identities = 14/32 (43%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ +PC NG CS Y C C G TG +C Sbjct: 2618 CALSPCKNGGSCSGDLSGYTCTCAFGWTGVNC 2649 Score = 35.5 bits (78), Expect = 0.62 Identities = 23/70 (32%), Positives = 26/70 (37%), Gaps = 5/70 (7%) Query: 1291 DHKFIDLNSYVADNGTLAGC-----PEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTG 1345 D KF+ L D+G A E + C PC NG CS IC CK TG Sbjct: 1017 DDKFVFLLRNYNDSGVAANAFQDSVIEALNSCYINPCKNGGTCSTSASKLICACKPTFTG 1076 Query: 1346 KDCADSTGPP 1355 C P Sbjct: 1077 SLCETECNIP 1086 Score = 34.3 bits (75), Expect = 1.4 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 1516 DCMLS-ICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG 1555 +C+ S IC CV ++ S C C + GP C+ C+ G Sbjct: 455 ECLDSRICAVERMCVNTYGSYQCVCTMDKYGPSCIYDCKSG 495 Score = 33.1 bits (72), Expect = 3.3 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 8/61 (13%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDG----DGSICR---SGSQCV-ARREGGILCQ 1090 ++ +TC C G+TGVNCE A V+G +G +C + C AR G+ C+ Sbjct: 2633 LSGYTCTCAFGWTGVNCEIRDFCALASVNGPACFNGGVCTNTPTSYTCTCARGFHGLRCE 2692 Query: 1091 G 1091 G Sbjct: 2693 G 2693 >SB_5376| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 1705 Score = 45.6 bits (103), Expect = 6e-04 Identities = 38/127 (29%), Positives = 50/127 (39%), Gaps = 12/127 (9%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGP--CGA-ARCVPDQTPKGYSCACEPG 1578 C + C + S TCTC A G ++ CE+G C A A C+ T ++CAC G Sbjct: 16 CHRNATCANTHGSFTCTCIAVYTGDD-INECEVGSHNCHADATCI--NTDGSFTCACNVG 72 Query: 1579 YTLTTSGCIESGKEECPG---GWWGGSACGPCACDVTRGYH--PHCNKENGKCHCK-ENH 1632 Y + C E E P A P H HC G +C +N Sbjct: 73 YAGNGAFCQEGFDRENPTLDINECQRDALAPIHNHYAHNCHVDAHCTNTKGSFYCTCKNG 132 Query: 1633 YKPEGTA 1639 Y +GTA Sbjct: 133 YSGDGTA 139 Score = 32.3 bits (70), Expect = 5.8 Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTL 1581 C P+++C + S CTCE G G V+ ++ C + D ++C + T Sbjct: 884 CHPHAQCTNTKGSFYCTCEKGYSG-DGVNCTDIDECNSETLSGDHKHLAHNCHSDANCTN 942 Query: 1582 T 1582 T Sbjct: 943 T 943 >SB_30234| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 5222 Score = 45.2 bits (102), Expect = 8e-04 Identities = 64/256 (25%), Positives = 89/256 (34%), Gaps = 29/256 (11%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570 C + LS C P S + C G + P + ++ PC A PD TPK Sbjct: 2527 CPKGTNAPLS-CEPGSYQPNRGQGNCTKCGPGSMCPY-QNMTKVEPCKAGYYCPDGTPK- 2583 Query: 1571 YSCACEPGYTLTTSGCIESGK-EECPGGWWGGSAC-----GPCA----CD--VTRGYHPH 1618 C G +G S + +CP G + A GPCA C+ Sbjct: 2584 ---PCGLGTYGNRTGLSSSDQCTDCPAGQFCSEAGLTMPKGPCAAGHFCEGGADSATPSP 2640 Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRACDAC 1677 +K C HY EGT P QC N++ AA C +C PG C+ Sbjct: 2641 SSKYPRNGLCPVGHYCVEGTQT--PEQCQPGTFRNTTGAAAFDHCLNCTPGWY---CEGF 2695 Query: 1678 ANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKD 1737 N+ P C Y CP + V P+ +F ++ TCD Sbjct: 2696 GNS----KPTDKCAPGYY-CPENSQASVSEPKKQFANYKLSHSGYNQKREGQPTCDPCPA 2750 Query: 1738 VPWQDPDMFNCTTATF 1753 + DPD C + + Sbjct: 2751 GYYCDPDAKKCPSHNY 2766 >SB_15312| Best HMM Match : EGF (HMM E-Value=7.1e-21) Length = 77 Score = 45.2 bits (102), Expect = 8e-04 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 DC S C + CV + TCTC G G C ++ C PC A C + + Sbjct: 4 DCAGSPCQNGATCVDGINKYTCTCAGGYTGTHCETDINECASSPCLNGATC--NDGVNLF 61 Query: 1572 SCACEPGY 1579 SC+C PGY Sbjct: 62 SCSCVPGY 69 Score = 41.5 bits (93), Expect = 0.009 Identities = 15/32 (46%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ +PC NGA C D + Y C C G+TG C Sbjct: 5 CAGSPCQNGATCVDGINKYTCTCAGGYTGTHC 36 Score = 41.1 bits (92), Expect = 0.012 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C+S+PC NGA C+D + + C C G+ G C Sbjct: 36 CETDINECASSPCLNGATCNDGVNLFSCSCVPGYIGVRC 74 Score = 35.5 bits (78), Expect = 0.62 Identities = 12/38 (31%), Positives = 21/38 (55%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 + +TC C G+TG +CET + + + +G+ C G Sbjct: 20 INKYTCTCAGGYTGTHCETDINECASSPCLNGATCNDG 57 >SB_53619| Best HMM Match : GPS (HMM E-Value=2.4e-15) Length = 457 Score = 45.2 bits (102), Expect = 8e-04 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 15/143 (10%) Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEIDYDWSPYSEEPLL 2235 L KPI + + N+ + S P+CV W T R WS GCH + Sbjct: 196 LTKPIVITV--RNNKTSNNSEMVPKCVFWDTKRRG--WSSSGCHLSFS--------NATI 243 Query: 2236 INCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSIS-LPLLLTSWAALCLIRGGA 2294 C C+H++ +AVL+ D+ + + S+ +Y ++S L + LT + L Sbjct: 244 TECKCDHMTNYAVLMSIGDMPIPAKHTRALSIVTYIGCTLSILGVFLTVVTLISL--PVL 301 Query: 2295 ATVSNSIHKHLIFSVFMAELLYL 2317 + IH +L +V ++++L+L Sbjct: 302 RSERTRIHCNLCIAVGVSQILFL 324 >SB_40564| Best HMM Match : Laminin_EGF (HMM E-Value=3.5e-12) Length = 186 Score = 45.2 bits (102), Expect = 8e-04 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 1569 KGYSC-ACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627 +G C C+PG+ T E G +EC GG+A C T+ HP +K Sbjct: 85 QGRQCDTCKPGFYRLTRDNPE-GCQEC-ACHHGGTANASNVCVTTQHEHPEQSKTVDPLS 142 Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 + + P EC Y AG+ C ATGQC CR V G+ C+ Sbjct: 143 DRWILFLPSA-CECDSGGTYPAGT----CNKATGQCQCRAHVTGKRCN 185 >SB_52271| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 89 Score = 44.8 bits (101), Expect = 0.001 Identities = 16/32 (50%), Positives = 21/32 (65%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S+PC NGA C+D + Y C C G TG +C Sbjct: 55 CASSPCQNGATCNDSVNKYTCSCIPGFTGTNC 86 Score = 40.7 bits (91), Expect = 0.016 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 8/54 (14%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLL 1370 C+ PC NG C+D + + C C G+TG C G DGML+ N +L Sbjct: 5 CAGDPCANGGTCTDGINGFTCTCPAGYTGNTCGT--------GFDGMLTINFVL 50 Score = 36.3 bits (80), Expect = 0.35 Identities = 24/82 (29%), Positives = 29/82 (35%), Gaps = 16/82 (19%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---------------VSACELGPCGAA 1560 DC C C + TCTC AG G C + C PC Sbjct: 4 DCAGDPCANGGTCTDGINGFTCTCPAGYTGNTCGTGFDGMLTINFVLDIDECASSPCQNG 63 Query: 1561 RCVPDQTPKGYSCACEPGYTLT 1582 D K Y+C+C PG+T T Sbjct: 64 ATCNDSVNK-YTCSCIPGFTGT 84 Score = 31.9 bits (69), Expect = 7.6 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 10/73 (13%) Query: 1039 VTSFTCQCPEGFTGVNCET----ILT-KASCEVDG-DGSICRSGSQCVARREGGILCQGC 1092 + FTC CP G+TG C T +LT ++D S C++G+ C + C Sbjct: 20 INGFTCTCPAGYTGNTCGTGFDGMLTINFVLDIDECASSPCQNGATC----NDSVNKYTC 75 Query: 1093 SIDAAYTTAVCEL 1105 S +T CE+ Sbjct: 76 SCIPGFTGTNCEM 88 >SB_16119| Best HMM Match : EGF (HMM E-Value=2e-20) Length = 76 Score = 44.8 bits (101), Expect = 0.001 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C C +S CTC AG G +C + C GPC D K Y+ Sbjct: 3 ECAGNPCANGGICKDGINSFKCTCPAGYTGSKCETDIDDCASGPCQNGATCNDGVNK-YT 61 Query: 1573 CACEPGYTLT 1582 C+C PG+T T Sbjct: 62 CSCIPGFTGT 71 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S PC NGA C+D + Y C C G TG +C Sbjct: 35 CETDIDDCASGPCQNGATCNDGVNKYTCSCIPGFTGTNC 73 Score = 37.5 bits (83), Expect = 0.15 Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+ PC NG C D +++ C C G+TG C Sbjct: 4 CAGNPCANGGICKDGINSFKCTCPAGYTGSKC 35 Score = 37.1 bits (82), Expect = 0.20 Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 + SF C CP G+TG CET + + +G+ C G Sbjct: 19 INSFKCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 56 Score = 33.9 bits (74), Expect = 1.9 Identities = 12/19 (63%), Positives = 13/19 (68%) Query: 1039 VTSFTCQCPEGFTGVNCET 1057 V +TC C GFTG NCET Sbjct: 57 VNKYTCSCIPGFTGTNCET 75 >SB_52861| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1487 Score = 44.4 bits (100), Expect = 0.001 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 14/106 (13%) Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSG-CIESGKEECPGGWWGGSACGPCACDVTRGY 1615 C A + D TP+ + C C+PGY SG C+ C G G P C + G+ Sbjct: 203 CSALQNCVD-TPEFFRCVCKPGYEQALSGQCV----PVCTQGCVNGKCTSPDVCTCSFGW 257 Query: 1616 -HPHCNKE---NGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCE 1657 P+C+ E NG HC N K + C C+ + GS CE Sbjct: 258 TGPNCSVECLCNGHGHC-ANATKRD---VCTDCRNHTTGSSCQYCE 299 >SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 933 Score = 44.4 bits (100), Expect = 0.001 Identities = 60/215 (27%), Positives = 75/215 (34%), Gaps = 20/215 (9%) Query: 1488 DVRIGTAQSLLNRPTVRENVR---DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEA--- 1541 DVR+G Q PT + VR G R C I + CE Sbjct: 383 DVRVGIHQDQSLNPTCNDRVRTVGQGQALRVQCNPPIPGRHIAIQMIGKGILTLCEVSVY 442 Query: 1542 GRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSG--CIESGKEECPGGWW 1599 R P C+L G + + C C PG+ + G CI+ +EC Sbjct: 443 SRTAP-LADLCQLDNGGCEQVCYNLCNLKVKCGCYPGFKMAYDGRTCIDI--DECQVN-N 498 Query: 1600 GGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAA 1659 GG C T G H HC NG + + Y E E C AG E+ CE Sbjct: 499 GGCDIFHGQCINTPGSH-HCACRNGYQLKENSKYVCEDLNE---CNVANAGCEH-ICENT 553 Query: 1660 TG--QCHCRPGVIGRACD-ACANAYAEVTPNSGCE 1691 G C CR G +A C N + N GCE Sbjct: 554 HGSFNCDCRQGYKLKAGGYGCENINECLVKNGGCE 588 Score = 33.5 bits (73), Expect = 2.5 Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 7/85 (8%) Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTC------EAGRVGPQCVSACELGP 1556 ++EN + C+ +C ++ C + S C C +AG G + ++ C + Sbjct: 525 LKENSKYVCEDLNECNVANAGCEHICENTHGSFNCDCRQGYKLKAGGYGCENINECLVKN 584 Query: 1557 CGAARCVPDQTPKGYSCACEPGYTL 1581 G D GY C C PGY L Sbjct: 585 GGCEHTCKDYEG-GYYCTCNPGYRL 608 >SB_26578| Best HMM Match : EGF (HMM E-Value=2.2e-35) Length = 136 Score = 44.4 bits (100), Expect = 0.001 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C ++ C C +C C+AG G C V+ C + PC ++ GYS Sbjct: 63 ECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNE-HGGYS 121 Query: 1573 CACEPGYT 1580 CAC+ G+T Sbjct: 122 CACKAGFT 129 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 19 CEQDVNECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNC 57 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 57 CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 95 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS PC NG C + Y C CK G TGK+C Sbjct: 95 CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 133 Score = 40.3 bits (90), Expect = 0.022 Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 26/147 (17%) Query: 1536 TCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592 +CTC++G G C V+ C PC ++ GYSCAC+ G+ T C E Sbjct: 7 SCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHG-GYSCACKVGF--TGKNC-EQDVN 62 Query: 1593 ECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCKENHYKPEGTAECLPCQCYAAG 1650 EC + PC G C E+G C CK + C Sbjct: 63 EC--------SVNPCK---NGGV---CKNEHGGYSCACKAGFTGKNCEQDVNECSVNPC- 107 Query: 1651 SENSSCEAATG--QCHCRPGVIGRACD 1675 C+ G C C+ G G+ C+ Sbjct: 108 KNGGVCKNEHGGYSCACKAGFTGKNCE 134 Score = 35.5 bits (78), Expect = 0.62 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 8/72 (11%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS--GSQCVARREG--GILCQ----GC 1092 +++C C GFTG NCE + + S +G +C++ G A + G G C+ C Sbjct: 5 AYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNEC 64 Query: 1093 SIDAAYTTAVCE 1104 S++ VC+ Sbjct: 65 SVNPCKNGGVCK 76 Score = 35.5 bits (78), Expect = 0.62 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 8/71 (11%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS--GSQCVARREG--GILCQ----GCS 1093 ++C C GFTG NCE + + S +G +C++ G A + G G C+ CS Sbjct: 44 YSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECS 103 Query: 1094 IDAAYTTAVCE 1104 ++ VC+ Sbjct: 104 VNPCKNGGVCK 114 Score = 35.1 bits (77), Expect = 0.82 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 10/63 (15%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C GFTG NCE + + C V+ C++G C GG C+ A +T Sbjct: 82 YSCACKAGFTGKNCEQDVNE--CSVNP----CKNGGVC-KNEHGG---YSCACKAGFTGK 131 Query: 1102 VCE 1104 CE Sbjct: 132 NCE 134 Score = 31.9 bits (69), Expect = 7.6 Identities = 29/110 (26%), Positives = 37/110 (33%), Gaps = 8/110 (7%) Query: 1571 YSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHC 1628 YSC C+ G+T E K C G + G +C G+ N E C Sbjct: 6 YSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKVGFTGK-NCEQDVNEC 64 Query: 1629 KENHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 N K G + C C AG +CE +C P G C Sbjct: 65 SVNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDVNECSVNPCKNGGVC 113 >SB_26267| Best HMM Match : TSP_C (HMM E-Value=0) Length = 2996 Score = 44.4 bits (100), Expect = 0.001 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAP 473 T G +T+ LD++ Y++ + TD+G G S ++I + D N+ P+ Sbjct: 1247 TMATSHGKLTLKAELDYEATTEYLIVMRITDTGRGTSGEIAIKIFVLDYNDNCPILPKVS 1306 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 YT ATD D G+N +T ++ S+ Sbjct: 1307 YTLKPIPPLQ-PQPFFTARATDKDSGLNGHVTPTIVSK 1343 Score = 43.6 bits (98), Expect = 0.002 Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 15/149 (10%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G L +A LD E Y ++++ TD S ++ I + ++D NDN P + +YT Sbjct: 1253 GKLTLKAELDYEATTEYLIVMRITDTGRGTSGEIA----IKIFVLDYNDNCPILPKVSYT 1308 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216 + + I +ATD D G N + I+ ++ +++ + V T Sbjct: 1309 L---KPIPPLQPQPFFTARATDKDSGLNGHVTPTIV----SKKYYMNNYTEIVWSNTTTQ 1361 Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +EQ I A DGG+P R + L I Sbjct: 1362 WEQT----YYIFAIDGGTPRRGDKIPLTI 1386 Score = 42.7 bits (96), Expect = 0.004 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 11/141 (7%) Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G +T LD E + YL+ + D G S ++I V+D NDN P+ + YT Sbjct: 1253 GKLTLKAELDYEATTEYLIVMRITDTG-RGTSGEIAIKIFVLDYNDNCPILPKVSYTLKP 1311 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 + L ATD D GLNG + + K + ++ + ++ +N E Sbjct: 1312 I-PPLQPQPFFTARATDKDSGLNGHVTPTIVSK-----KYYMNNYTEIVWSNTTTQWEQ- 1364 Query: 651 ATHDLKAVAIDGGTPPQSSTV 671 T+ + AIDGGTP + + Sbjct: 1365 -TYYI--FAIDGGTPRRGDKI 1382 Score = 41.9 bits (94), Expect = 0.007 Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 16/141 (11%) Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQES 265 G ++L LDYE Y +V+R D G + S + I + D NDN P S + Sbjct: 1253 GKLTLKAELDYEATTEYLIVMRITDTGRGT-SGEIAIKIFVLDYNDNCPILPKVSYTLKP 1311 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 + P + R A D D G+N +T T+ K Y N I W T+ Sbjct: 1312 IPPLQPQPFFTAR--ATDKDSGLNGHVTPTIVSKKYYMNNYTEIV------WSNTT---- 1359 Query: 326 RETQAKYQLLVTATDGGDPPR 346 TQ + + A DGG P R Sbjct: 1360 --TQWEQTYYIFAIDGGTPRR 1378 Score = 31.9 bits (69), Expect = 7.6 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 9/82 (10%) Query: 747 ELVTMVDLDYESPRKKYELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNY 804 +L +LDYE+ + Y +V+R ++ ++I V D NDN P++ Sbjct: 1254 KLTLKAELDYEATTE-YLIVMRITDTGRGTSGEIAIKIFVLDYNDNCPILPKVSYTLK-- 1310 Query: 805 KDCFPVGPFGRVPAYDADVTDK 826 P+ P P + A TDK Sbjct: 1311 ----PIPPLQPQPFFTARATDK 1328 >SB_26085| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 484 Score = 44.4 bits (100), Expect = 0.001 Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 21/140 (15%) Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAG-------RVGPQCVSACEL---GPCG 1558 D C+ R +C C + C+ + S C CE G + CV E G C Sbjct: 236 DKCRDRNECAYKNCGVGATCLNALGSYACQCEPGFRLDRTLGLSGVCVDMDECLVPGSC- 294 Query: 1559 AARCVPDQTPKGYSCACEPGYTL--TTSGCIESGK----EECPGGWWGGSACGPCACDVT 1612 V KG++C CE GY + + CI+ + CP G + G CD Sbjct: 295 PEHSVCTNHVKGFTCECESGYLMDDLKAHCIDVDECALGATCPSGTNCVNTQGSFYCDCG 354 Query: 1613 RGYHPHCNKENGKCHCKENH 1632 GYH NG C +H Sbjct: 355 HGYH----AVNGTCQGMFDH 370 Score = 40.7 bits (91), Expect = 0.016 Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 35/186 (18%) Query: 1521 ICPPYSKCVTSWDSSTCTC---EAGRVGPQC--VSACELGPCG-AARCVPDQTPKGYSCA 1574 ICP + CV + S CTC + G +C + C CG A C+ Y+C Sbjct: 208 ICPENTNCVNTHGSYECTCLGPFSPWFGDKCRDRNECAYKNCGVGATCL--NALGSYACQ 265 Query: 1575 CEPGY----TLTTSG-CIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 CEPG+ TL SG C++ + PG S C + +G+ C C+ Sbjct: 266 CEPGFRLDRTLGLSGVCVDMDECLVPGSCPEHSVC----TNHVKGF---------TCECE 312 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689 + + A C+ A G ++C + T C G CD C + Y V N Sbjct: 313 SGYLMDDLKAHCIDVDECALG---ATCPSGT-NCVNTQGSF--YCD-CGHGYHAV--NGT 363 Query: 1690 CEVVYD 1695 C+ ++D Sbjct: 364 CQGMFD 369 >SB_54230| Best HMM Match : EGF (HMM E-Value=0) Length = 1359 Score = 44.4 bits (100), Expect = 0.001 Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 2/41 (4%) Query: 1310 CPEKRSRC--SSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + ++C SS PC NGA CS+L TY C G+TGK C Sbjct: 913 CEKGINKCIPSSNPCKNGATCSNLHGTYTCTYATGYTGKHC 953 Score = 43.2 bits (97), Expect = 0.003 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + CS ++PC NGA C +L Y C C G TGK C Sbjct: 834 CEKDVNECSQNSPCRNGATCLNLPGAYTCTCASGFTGKHC 873 Score = 41.9 bits (94), Expect = 0.007 Identities = 16/28 (57%), Positives = 18/28 (64%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 PC N A CS+L TY C C G+TGK C Sbjct: 1027 PCKNRATCSNLHGTYTCTCATGYTGKHC 1054 Score = 41.5 bits (93), Expect = 0.009 Identities = 46/162 (28%), Positives = 61/162 (37%), Gaps = 17/162 (10%) Query: 1511 CQSRAD-CML-SICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC-ELGPC-GAARCV 1563 C++ D C + S C + C + TC C G G C V+ C + PC A C+ Sbjct: 795 CETDIDECKITSSCKNGATCTNLHGTYTCICATGYKGEHCEKDVNECSQNSPCRNGATCL 854 Query: 1564 PDQTPKGYSCACEPGYT-LTTSGCIESGKEE--CPGGWWGGSACGP--CACDVTRGYHPH 1618 P Y+C C G+T I+ K + C G ++ G C+C H Sbjct: 855 --NLPGAYTCTCASGFTGKHCEKDIDECKVQNPCRNGATCINSIGDYRCSCCPPCFTGQH 912 Query: 1619 CNKENGKCHCKENHYKPEGTAECL--PCQC-YAAGSENSSCE 1657 C K KC N K T L C YA G CE Sbjct: 913 CEKGINKCIPSSNPCKNGATCSNLHGTYTCTYATGYTGKHCE 954 Score = 38.3 bits (85), Expect = 0.088 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 7/64 (10%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL-GPC-GAARCVPDQTPKGYSCACE 1576 C + C + TCTC G G C + C++ PC A C+ + Y C+C Sbjct: 1028 CKNRATCSNLHGTYTCTCATGYTGKHCEKDIDECKVQNPCRNGATCI--NSMGDYRCSCP 1085 Query: 1577 PGYT 1580 PG+T Sbjct: 1086 PGFT 1089 Score = 37.9 bits (84), Expect = 0.12 Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 8/105 (7%) Query: 1248 PTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVG---CISDFYIDHKFIDLNSYVADN 1304 PT C++ + L+ G P++ + ++ D G C + K D Sbjct: 695 PTPRCNK----SDTLECVGAPSVNYVYTLQEDDPCGSHLCKNGATCTSKLGKYRCSCPDG 750 Query: 1305 GTLAGCPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T C + C S PC N C + + +Y C C G TGK+C Sbjct: 751 LTGRHCETDLNECKPSNPCRNDGTCVNTYGSYSCACPTGLTGKNC 795 Score = 37.5 bits (83), Expect = 0.15 Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 5/39 (12%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079 S++C CP G TG NCET + + C++ S C++G+ C Sbjct: 781 SYSCACPTGLTGKNCETDIDE--CKIT---SSCKNGATC 814 Score = 37.1 bits (82), Expect = 0.20 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C ++ C NGA C++L TY C C G+ G+ C Sbjct: 795 CETDIDECKITSSCKNGATCTNLHGTYTCICATGYKGEHC 834 Score = 36.3 bits (80), Expect = 0.35 Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 8/64 (12%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 ++TC C GFTG +CE + + C+V CR+G+ C+ G C C +T Sbjct: 859 AYTCTCASGFTGKHCEKDIDE--CKVQNP---CRNGATCI-NSIGDYRCSCC--PPCFTG 910 Query: 1101 AVCE 1104 CE Sbjct: 911 QHCE 914 Score = 35.5 bits (78), Expect = 0.62 Identities = 42/162 (25%), Positives = 57/162 (35%), Gaps = 27/162 (16%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL-GPC-GAARCVPDQTPKGYSCACE 1576 C CV ++ S +C C G G C + C++ C A C Y+C C Sbjct: 769 CRNDGTCVNTYGSYSCACPTGLTGKNCETDIDECKITSSCKNGATCT--NLHGTYTCICA 826 Query: 1577 PGYTLTTSGCIESGKEECP--GGWWGGSAC----GPCACDVTRGY-HPHCNKENGKCHCK 1629 GY C E EC G+ C G C G+ HC K+ +C + Sbjct: 827 TGY--KGEHC-EKDVNECSQNSPCRNGATCLNLPGAYTCTCASGFTGKHCEKDIDECKVQ 883 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPGV 1669 A C+ + G SC TGQ HC G+ Sbjct: 884 N---PCRNGATCI----NSIGDYRCSCCPPCFTGQ-HCEKGI 917 Score = 35.5 bits (78), Expect = 0.62 Identities = 15/40 (37%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C PC NGA C + Y C C G TG+ C Sbjct: 1054 CEKDIDECKVQNPCRNGATCINSMGDYRCSCPPGFTGQHC 1093 Score = 35.1 bits (77), Expect = 0.82 Identities = 32/113 (28%), Positives = 43/113 (38%), Gaps = 13/113 (11%) Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL-GPC-GAARCVPDQTPKGYSCA 1574 S C + C+ + TCTC +G G C + C++ PC A C+ SC Sbjct: 845 SPCRNGATCLNLPGAYTCTCASGFTGKHCEKDIDECKVQNPCRNGATCINSIGDYRCSC- 903 Query: 1575 CEPGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNK 1621 C P +T + CI S C G + G C GY HC K Sbjct: 904 CPPCFTGQHCEKGINKCIPS-SNPCKNGATCSNLHGTYTCTYATGYTGKHCEK 955 Score = 33.5 bits (73), Expect = 2.5 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 5/40 (12%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV 1080 ++TC C G+TG +CE + + C+V CR+G+ C+ Sbjct: 1040 TYTCTCATGYTGKHCEKDIDE--CKVQNP---CRNGATCI 1074 Score = 32.7 bits (71), Expect = 4.4 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 1042 FTCQCPEGFTGVNCETILT--KASCEVDGDGSICRSGSQCVARREGGILCQGC--SIDAA 1097 + C CP+G TG +CET L K S DG+ + G+ + C ID Sbjct: 743 YRCSCPDGLTGRHCETDLNECKPSNPCRNDGTCVNTYGSYSCACPTGLTGKNCETDIDEC 802 Query: 1098 YTTAVCE 1104 T+ C+ Sbjct: 803 KITSSCK 809 >SB_33876| Best HMM Match : EGF (HMM E-Value=2.4e-08) Length = 164 Score = 44.4 bits (100), Expect = 0.001 Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355 C+S PC NGA C+D + Y C C G TG +C ++ G P Sbjct: 5 CASDPCQNGATCNDGLNNYTCACISGFTGTNC-ETIGKP 42 Score = 34.7 bits (76), Expect = 1.1 Identities = 12/20 (60%), Positives = 15/20 (75%) Query: 1039 VTSFTCQCPEGFTGVNCETI 1058 + ++TC C GFTG NCETI Sbjct: 20 LNNYTCACISGFTGTNCETI 39 >SB_3578| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 355 Score = 44.4 bits (100), Expect = 0.001 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 1310 CPEK--RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CP+ + CSS PC NGA CS Y C C G+ G+DC Sbjct: 312 CPDNVGANPCSSNPCRNGATCSSNEGQYKCKCPPGYGGRDC 352 >SB_58129| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 82 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 1644 CQCYAAGSENSS--CEAATGQCHCRPGVIGRACDAC 1677 C C+ AG+ N+S C+ GQC C+ V GR CD C Sbjct: 46 CGCHGAGTVNASDVCDKLDGQCPCKQAVTGRTCDTC 81 >SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 4232 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/32 (53%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSSAPC NG C+ + Y C C G TG DC Sbjct: 21 CSSAPCQNGGTCTVVSGGYSCTCLPGFTGNDC 52 >SB_48589| Best HMM Match : EGF (HMM E-Value=2e-19) Length = 112 Score = 44.0 bits (99), Expect = 0.002 Identities = 14/39 (35%), Positives = 23/39 (58%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S+PC NG C++ + + C+C+ G+ GK C Sbjct: 34 CESEIDECESSPCLNGGTCTNHVNYFHCECRAGYAGKQC 72 Score = 42.3 bits (95), Expect = 0.005 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+S+PC NG+ C D + Y C C G++G C Sbjct: 72 CQTDIDECASSPCLNGSTCEDGVNGYTCSCVVGYSGPQC 110 Score = 41.9 bits (94), Expect = 0.007 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 7/75 (9%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPD 1565 C+S D C S C C + C C AG G QC + C PC + C + Sbjct: 34 CESEIDECESSPCLNGGTCTNHVNYFHCECRAGYAGKQCQTDIDECASSPCLNGSTC--E 91 Query: 1566 QTPKGYSCACEPGYT 1580 GY+C+C GY+ Sbjct: 92 DGVNGYTCSCVVGYS 106 Score = 32.7 bits (71), Expect = 4.4 Identities = 25/95 (26%), Positives = 30/95 (31%), Gaps = 9/95 (9%) Query: 1534 SSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT--LTTSGCI 1587 S C C+AG G +C + CE PC C + C C GY + Sbjct: 20 SCACLCKAGFTGLECESEIDECESSPCLNGGTCT--NHVNYFHCECRAGYAGKQCQTDID 77 Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNK 1621 E C G C GY P C K Sbjct: 78 ECASSPCLNGSTCEDGVNGYTCSCVVGYSGPQCGK 112 Score = 32.7 bits (71), Expect = 4.4 Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548 CQ+ D C S C S C + TC+C G GPQC Sbjct: 72 CQTDIDECASSPCLNGSTCEDGVNGYTCSCVVGYSGPQC 110 >SB_32722| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 603 Score = 44.0 bits (99), Expect = 0.002 Identities = 41/141 (29%), Positives = 50/141 (35%), Gaps = 26/141 (18%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA--CELGPC-GAARCVPDQTPKGYSC 1573 C + C + CV + S C C AG GP C + C PC CVP + GY C Sbjct: 280 CHPNPCHNGATCVATDSSFDCDCVAGWTGPLCQTRQYCIPNPCQNGGTCVPQE--NGYRC 337 Query: 1574 ACEPGYTLTTSGCIESGKEECPGGWWGGSACGP------CAC-----------DVTRGYH 1616 C+ Y + C E P G C CAC D Sbjct: 338 TCQANY--EGNDC-ERANPCSPNPCRNGGTCSEMNNAAVCACGVQFEGNQCEIDKCAKCD 394 Query: 1617 PHCNKENGKCHCKENHYKPEG 1637 H NGKC C E Y+ +G Sbjct: 395 MHATCRNGKCVCMEG-YEGDG 414 Score = 38.7 bits (86), Expect = 0.066 Identities = 49/196 (25%), Positives = 60/196 (30%), Gaps = 20/196 (10%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS-ACELGPCGAARCVPDQTPK 1569 C+ R+ C + C CV C C G G C + C PC ++ Sbjct: 170 CEERSICFSNPCLHGGSCVDEMYGFRCNCPIGYNGVTCQNHVCRPNPCQNGGSCLEEGGL 229 Query: 1570 GYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCAC-DVTRGYHPHCNKENGKCHC 1628 G C C+ GY C C G C C D G CNK CH Sbjct: 230 G-RCICQMGY--HGQHCENDRCRFCSVN--ADCILGHCVCKDGYHGDGKTCNK--NVCHP 282 Query: 1629 KENHYKPE--GTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686 H T C C AG C+ C P G C N Y Sbjct: 283 NPCHNGATCVATDSSFDCDC-VAGWTGPLCQTRQ-YCIPNPCQNGGTCVPQENGY----- 335 Query: 1687 NSGCEVVYDG--CPRS 1700 C+ Y+G C R+ Sbjct: 336 RCTCQANYEGNDCERA 351 Score = 37.5 bits (83), Expect = 0.15 Identities = 46/176 (26%), Positives = 63/176 (35%), Gaps = 21/176 (11%) Query: 1530 TSWDSSTCTCEAGRVGPQC--VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCI 1587 TS CTC G G C ++ C PC A ++ Y C C G+ T C Sbjct: 114 TSVTGYQCTCREGFKGFDCEEINLCVPNPCKNAGTCTEKGGGRYDCTCPIGFKGVT--CE 171 Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647 E GGS C D G+ +C C +NH C P C Sbjct: 172 ERSICFSNPCLHGGS----CV-DEMYGFRCNCPIGYNGVTC-QNHV-------CRPNPCQ 218 Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAG 1703 GS E G+C C+ G G+ C+ + V N+ C + + C + G Sbjct: 219 NGGS--CLEEGGLGRCICQMGYHGQHCENDRCRFCSV--NADCILGHCVCKDGYHG 270 Score = 37.5 bits (83), Expect = 0.15 Identities = 16/44 (36%), Positives = 22/44 (50%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355 E+RS C S PC +G C D + C+C G+ G C + P Sbjct: 171 EERSICFSNPCLHGGSCVDEMYGFRCNCPIGYNGVTCQNHVCRP 214 Score = 37.1 bits (82), Expect = 0.20 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 3/52 (5%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC--ADSTGP-PWRFGG 1360 + R C PC NG C + Y C C+ + G DC A+ P P R GG Sbjct: 312 QTRQYCIPNPCQNGGTCVPQENGYRCTCQANYEGNDCERANPCSPNPCRNGG 363 Score = 35.9 bits (79), Expect = 0.47 Identities = 14/32 (43%), Positives = 17/32 (53%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C PC+NGA C ++ CDC G TG C Sbjct: 280 CHPNPCHNGATCVATDSSFDCDCVAGWTGPLC 311 Score = 35.9 bits (79), Expect = 0.47 Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 5/68 (7%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA--CELGPC-GAARCVPDQT 1567 CQ+R C+ + C CV + CTC+A G C A C PC C + Sbjct: 311 CQTRQYCIPNPCQNGGTCVPQENGYRCTCQANYEGNDCERANPCSPNPCRNGGTC--SEM 368 Query: 1568 PKGYSCAC 1575 CAC Sbjct: 369 NNAAVCAC 376 Score = 35.5 bits (78), Expect = 0.62 Identities = 13/34 (38%), Positives = 17/34 (50%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 S C PC NG +C+ + + Y C C G G C Sbjct: 21 SFCEPVPCQNGGQCTVVPNGYECTCSPGFMGTHC 54 Score = 35.5 bits (78), Expect = 0.62 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E+ + CS PC NG CS++ + +C C G C Sbjct: 349 ERANPCSPNPCRNGGTCSEMNNAAVCACGVQFEGNQC 385 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Query: 1315 SRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCAD 1350 ++C PC NG C+ Y C C+EG G DC + Sbjct: 97 NKCHPNPCRNGGMCTGTTSVTGYQCTCREGFKGFDCEE 134 >SB_12742| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1077 Score = 44.0 bits (99), Expect = 0.002 Identities = 60/210 (28%), Positives = 79/210 (37%), Gaps = 45/210 (21%) Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQCVSACELGP---CGA-ARC 1562 C +C+LS C +S C + S TC C G ++ +CV E C A +RC Sbjct: 354 CNDIDECVLSAPNCSSHSYCSNTMGSYTCRCHVGFIKLNGECVDLNECQKHFYCPATSRC 413 Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIE--------------------SGKEE--CPGGWWG 1600 V T Y C C GY S CI+ G E C G++G Sbjct: 414 V--NTLGSYKCRCLEGYHSAGSSCIDIDECKTSAHNCHANATCVNKMGSYECVCKEGYFG 471 Query: 1601 -GSACGPCACDVTR-----GYHPHCNKENG--KCHCKENHYKPEGTAECL-PCQCYAAGS 1651 G+ C AC TR C EN KC CK + T E + CQ + Sbjct: 472 NGTHCEVDAC-FTRPSRLCDKDAVCRLENNAIKCMCKAGYTGDGITCEDVNECQLPGSCH 530 Query: 1652 ENSSCEAATGQ--CHCRPGVIGRACDACAN 1679 +++C G C C G IG D C + Sbjct: 531 VHATCANTNGSHVCTCNKGFIGEG-DLCTD 559 >SB_11540| Best HMM Match : EGF (HMM E-Value=1.5e-25) Length = 103 Score = 44.0 bits (99), Expect = 0.002 Identities = 17/34 (50%), Positives = 21/34 (61%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C S PC NGA C+D + Y C CK G+TG C Sbjct: 67 NECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVC 100 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/34 (50%), Positives = 21/34 (61%) Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + C S PC NGA C+D + Y C CK G+TG C Sbjct: 3 NECQSNPCLNGATCTDHVNGYTCKCKLGYTGIVC 36 Score = 33.1 bits (72), Expect = 3.3 Identities = 12/28 (42%), Positives = 16/28 (57%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYIC 1337 C + + C S PC NGA C+D + Y C Sbjct: 36 CQQDINECQSNPCLNGATCTDHVNGYTC 63 Score = 32.3 bits (70), Expect = 5.8 Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 1533 DSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580 + +TCT ++ C+ PC D GY+C+C+ GYT Sbjct: 50 NGATCTDHVNGYTCSYINECQSNPCLNGATCTDHV-NGYTCSCKLGYT 96 Score = 31.9 bits (69), Expect = 7.6 Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 4/62 (6%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C + C + C + TC C+ G G C ++ C+ PC D GY+ Sbjct: 4 ECQSNPCLNGATCTDHVNGYTCKCKLGYTGIVCQQDINECQSNPCLNGATCTDHV-NGYT 62 Query: 1573 CA 1574 C+ Sbjct: 63 CS 64 >SB_45954| Best HMM Match : VWA (HMM E-Value=4e-26) Length = 715 Score = 43.6 bits (98), Expect = 0.002 Identities = 17/32 (53%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 CSSAPC NG C+ + Y C C G TG DC Sbjct: 28 CSSAPCQNGGTCTVVSGGYSCACLPGFTGNDC 59 Score = 37.5 bits (83), Expect = 0.15 Identities = 21/74 (28%), Positives = 31/74 (41%) Query: 1276 VKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTY 1335 V+ KD G S+ + + LNS V G + C++ C NG C+ + Sbjct: 640 VELKDLTGVDSNVFTTTSYDGLNSLVESIRNAVGNAPLKVVCNANACKNGGTCNVYGVGF 699 Query: 1336 ICDCKEGHTGKDCA 1349 C C TG DC+ Sbjct: 700 NCTCPIQWTGADCS 713 >SB_5527| Best HMM Match : EGF_CA (HMM E-Value=1e-26) Length = 83 Score = 43.6 bits (98), Expect = 0.002 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 11/80 (13%) Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELGP--CGA-ARCVPDQ 1566 +C L+I CP CV + S TC C+ G V C + C LG C A A CV + Sbjct: 4 ECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCVNND 63 Query: 1567 TPKGYSCACEPGYTLTTSGC 1586 Y+C C+PG+TL + C Sbjct: 64 G--SYTCRCKPGFTLVYNKC 81 >SB_33579| Best HMM Match : Laminin_G_2 (HMM E-Value=3.2e-34) Length = 1071 Score = 43.6 bits (98), Expect = 0.002 Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 1281 FVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC- 1339 FVGC+ D I I S + G G + C PC NG C ++ Y CDC Sbjct: 344 FVGCMKDVKIRGVKIRDQSVIRYRGPKFGVCPLENYCFPNPCLNGGVCHIWYNKYTCDCY 403 Query: 1340 KEGHTGKDC 1348 K +TG C Sbjct: 404 KTFYTGSTC 412 >SB_30923| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 642 Score = 43.6 bits (98), Expect = 0.002 Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 3/73 (4%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS--ACELGPC-GAARCVPDQT 1567 CQ R C C CV + C C G +G C AC PC C T Sbjct: 32 CQERNYCSSMPCLNGGSCVEIPGAFKCGCPFGFLGTVCEERDACHPNPCKNGGTCTRSDT 91 Query: 1568 PKGYSCACEPGYT 1580 G+ C C+ G+T Sbjct: 92 ESGFVCVCKEGFT 104 Score = 43.6 bits (98), Expect = 0.002 Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 1305 GTLAGCPEKRSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDC 1348 G L E+R C PC NG C SD ++C CKEG TG+ C Sbjct: 63 GFLGTVCEERDACHPNPCKNGGTCTRSDTESGFVCVCKEGFTGEHC 108 Score = 38.7 bits (86), Expect = 0.066 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC--ADSTGP-PWRFGG 1360 ++R+ CSS PC NG C ++ + C C G G C D+ P P + GG Sbjct: 33 QERNYCSSMPCLNGGSCVEIPGAFKCGCPFGFLGTVCEERDACHPNPCKNGG 84 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/38 (36%), Positives = 19/38 (50%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 C+S PC NG C + +C CK TG C + + P Sbjct: 371 CTSNPCQNGGTCMNDKGKAVCRCKGKWTGVTCRECSCP 408 >SB_27599| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2937 Score = 43.6 bits (98), Expect = 0.002 Identities = 15/32 (46%), Positives = 21/32 (65%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S PC NG C D ++Y+C C G+TG +C Sbjct: 137 CASEPCLNGGACVDGANSYLCSCTAGYTGINC 168 Score = 40.3 bits (90), Expect = 0.022 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C S C C+ + +C C G +GP C V C PC CV Y Sbjct: 98 ECAASPCLNDGTCIDGPGNYSCICSTGFLGPTCEINVDDCASEPCLNGGACV--DGANSY 155 Query: 1572 SCACEPGYT 1580 C+C GYT Sbjct: 156 LCSCTAGYT 164 Score = 35.1 bits (77), Expect = 0.82 Identities = 25/77 (32%), Positives = 31/77 (40%), Gaps = 10/77 (12%) Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100 +++C C GF G CE + + E C +G CV G CS A YT Sbjct: 116 NYSCICSTGFLGPTCEINVDDCASEP------CLNGGACV----DGANSYLCSCTAGYTG 165 Query: 1101 AVCELRARSFPVSSFLT 1117 CE R F V S T Sbjct: 166 INCETAIRGFLVQSTKT 182 Score = 32.7 bits (71), Expect = 4.4 Identities = 12/32 (37%), Positives = 15/32 (46%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+++PC N C D Y C C G G C Sbjct: 99 CAASPCLNDGTCIDGPGNYSCICSTGFLGPTC 130 >SB_42661| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1717 Score = 43.2 bits (97), Expect = 0.003 Identities = 53/198 (26%), Positives = 69/198 (34%), Gaps = 25/198 (12%) Query: 1517 CMLSICPPYSKC-------VTSWDSSTCT-CEAGRVGPQCVSACELGPCGAARCVPDQTP 1568 C ++ CP C T+ D+ CT C G +GP C C G A CV D Sbjct: 1456 CHITDCPGTPNCFDRGFCNTTNRDTPACTDCVKGWMGPACNDPCVHGREVAGSCVCDPCY 1515 Query: 1569 KGYSCACE-PGYTLTTSGCIESGKEEC---PGGWWGGSACGPCAC---DVTRGYHPHCNK 1621 G C E G+ C+E GK +C G + G C C D + CN Sbjct: 1516 TGSGCQSECSGH----GECVE-GKCKCNEAAGDAYVGVNCELPGCPGRDGNCNGNGFCNL 1570 Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAAT-GQCHCRPGVIGRACD-ACAN 1679 + KC C + L C S C +C C P G C+ C N Sbjct: 1571 KLQKCECYPGW--AGDACDKLDCPGSPPCSGQGECSNTNPRRCQCFPKWGGEKCEIPCLN 1628 Query: 1680 AYAEVTPNS-GCEVVYDG 1696 Y + C+ Y G Sbjct: 1629 GYNYGNASDCVCDACYSG 1646 Score = 36.3 bits (80), Expect = 0.35 Identities = 48/168 (28%), Positives = 64/168 (38%), Gaps = 36/168 (21%) Query: 1509 DGCQSRADCMLSI-CPPYSKCVTSWDSSTCT-CEAGRVGPQCVSACELGPCGAARCVPDQ 1566 DGC+ DC + C C TS+D CT C G +G C C G VP Sbjct: 1323 DGCEI-PDCPGNPDCAGRGHCNTSFDPPRCTNCSQGWMGQACEDLCVHGTQ-----VPMD 1376 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 + +C C+ +T GC EC G G G CACD G+ + G Sbjct: 1377 SG---NCQCDACFT--GRGC----NVECSGH--GQCVNGACACDTLAGWRGSLCEVPG-- 1423 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C K +C S + +C++A +C C PG G C Sbjct: 1424 -CAGVDGK-----DC---------SGHGTCDSANHKCICDPGWSGIGC 1456 >SB_14079| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 546 Score = 43.2 bits (97), Expect = 0.003 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 7/84 (8%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572 +C S C CV + +CTC AG G C + C PC D G++ Sbjct: 182 ECKSSPCNNGRTCVDGINRYSCTCAAGFTGTNCETDIDECAGNPCANGGTCKDGI-NGFT 240 Query: 1573 CACEPGYTLTTSGCIESGKEECPG 1596 C C GY+ +T C E +EC G Sbjct: 241 CECPVGYSGST--C-EIDIDECAG 261 Score = 41.9 bits (94), Expect = 0.007 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 10/77 (12%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + FTC+CP G++G CE + + + G+ C +G C + GI C Y Sbjct: 236 INGFTCECPVGYSGSTCEIDIDECA------GNPCANGGTC----KDGINGFTCECHVGY 285 Query: 1099 TTAVCELRARSFPVSSF 1115 + + CE+ V+SF Sbjct: 286 SGSTCEIEGLILSVNSF 302 Score = 40.3 bits (90), Expect = 0.022 Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 7/57 (12%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DGMLSF 1366 C S+PC NG C D + Y C C G TG +C + G P GG DG+ F Sbjct: 183 CKSSPCNNGRTCVDGINRYSCTCAAGFTGTNCETDIDECAGNPCANGGTCKDGINGF 239 Score = 39.1 bits (87), Expect = 0.050 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 10/67 (14%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + ++C C GFTG NCET + + + G+ C +G C + GI C Y Sbjct: 198 INRYSCTCAAGFTGTNCETDIDECA------GNPCANGGTC----KDGINGFTCECPVGY 247 Query: 1099 TTAVCEL 1105 + + CE+ Sbjct: 248 SGSTCEI 254 Score = 39.1 bits (87), Expect = 0.050 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 7/68 (10%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG- 1360 T C C+ PC NG C D + + C+C G++G C + G P GG Sbjct: 210 TGTNCETDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTCEIDIDECAGNPCANGGT 269 Query: 1361 --DGMLSF 1366 DG+ F Sbjct: 270 CKDGINGF 277 Score = 37.5 bits (83), Expect = 0.15 Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C+ PC NG C D + + C+C G++G C Sbjct: 252 CEIDIDECAGNPCANGGTCKDGINGFTCECHVGYSGSTC 290 Score = 35.9 bits (79), Expect = 0.47 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 1044 CQCPEGFTGVNCET---ILTKASCEVDGD----GSICRSGSQCVARREGGILCQGCSIDA 1096 C CP GF+G CE+ +T + +D D S C +G CV GI C+ A Sbjct: 152 CHCPAGFSGDKCESKLLYITNLTPLIDNDDECKSSPCNNGRTCV----DGINRYSCTCAA 207 Query: 1097 AYTTAVCE 1104 +T CE Sbjct: 208 GFTGTNCE 215 Score = 35.9 bits (79), Expect = 0.47 Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 5/77 (6%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C++ D C + C C + TC C G G C + C PC D Sbjct: 214 CETDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTCEIDIDECAGNPCANGGTCKDG 273 Query: 1567 TPKGYSCACEPGYTLTT 1583 G++C C GY+ +T Sbjct: 274 I-NGFTCECHVGYSGST 289 >SB_7343| Best HMM Match : EGF (HMM E-Value=0) Length = 1233 Score = 43.2 bits (97), Expect = 0.003 Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 18/168 (10%) Query: 1536 TCTCEAGRVGPQCVSA--CEL-GPCG----AARCVPDQTPKGYSCACEPGYTLTTSGCIE 1588 +CTC +G G C CE PC R + GY+C C PGY T C E Sbjct: 278 SCTCVSGYTGRNCTERDLCEPENPCANGGTCQRTIGSDGSLGYNCTCAPGYLGT--NCTE 335 Query: 1589 SGKEECPGGWWGGSAC-GPCACDVTRGYHPHCNKENGKCHCKE-NHYKPEGTAECLPCQC 1646 E G C D + GY+ C +C E N +P PC Sbjct: 336 RNLCEPVNPCINGGTCKRTVGSDGSPGYNCTCAPGYLGTNCTERNLCEPVN-----PCAN 390 Query: 1647 YAAGSENSSCEAATG-QCHCRPGVIGRACDACANAYAEV-TPNSGCEV 1692 + + G C C G G C + + V TP+S ++ Sbjct: 391 GGTCKRTVGSDGSAGYNCTCIEGFTGENCSEITPSSSSVPTPSSSSDI 438 Score = 41.9 bits (94), Expect = 0.007 Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 11/72 (15%) Query: 1312 EKRSRCSSAPCYNGAECSD----LWDTYICDCKEGHTGKDCA----DSTGPPWRFGG--- 1360 E+ + C +PC N A C D L D Y C C G TGK+C D P GG Sbjct: 167 EELNSCLRSPCQNQATCLDINAGLRDAYNCSCVPGFTGKNCEINIDDCASRPCLNGGLCV 226 Query: 1361 DGMLSFNPLLRP 1372 DG+ S++ L +P Sbjct: 227 DGVNSYSCLCQP 238 Score = 39.9 bits (89), Expect = 0.029 Identities = 46/171 (26%), Positives = 59/171 (34%), Gaps = 19/171 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV----SACELGPC---GAA-RCVP-DQ 1566 DC C CV +S +C C+ G C + C+ PC G R V D Sbjct: 213 DCASRPCLNGGLCVDGVNSYSCLCQPDINGNNCEIVTPNRCQPNPCENGGTCDRTVGNDG 272 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC-GPCACDVTRGYHPHCNKENGK 1625 + YSC C GY T C E E G C D + GY+ C Sbjct: 273 SRSNYSCTCVSGY--TGRNCTERDLCEPENPCANGGTCQRTIGSDGSLGYNCTCAPGYLG 330 Query: 1626 CHCKE-NHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRAC 1674 +C E N +P PC + + G C C PG +G C Sbjct: 331 TNCTERNLCEPVN-----PCINGGTCKRTVGSDGSPGYNCTCAPGYLGTNC 376 Score = 37.9 bits (84), Expect = 0.12 Identities = 75/325 (23%), Positives = 119/325 (36%), Gaps = 38/325 (11%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQ-----CVARR-EGGILCQ-GCSI 1094 + C+CP G+ G +C I +G I + SQ C+ + G+ C+ SI Sbjct: 709 YDCKCPSGYQGKSCTLISACVGDPCNGGRCIVSNSSQPQNHVCLCPYGKAGVSCEHDISI 768 Query: 1095 DAAYTTAVCELRARSFPVSSFLTFPGLKRRH-RIHLKLKFATQTTSGLLLYNG--RYNER 1151 T L + + PG + ++ LLLY+ RY Sbjct: 769 SVPGFTM---LHGYASYIQYATPTPGASHFDITMQFRVDDPIAWNDALLLYSSQDRYLGG 825 Query: 1152 HDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMI 1211 DF+AL L + + ++LG G + I WHTV + Sbjct: 826 GDFIALGLKDGQ--------ILLQYNLGSGLARIRSCSLNKTQDWHTVTAGRSGPEGYVY 877 Query: 1212 LDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIP 1271 D+C+KV + GL F V E+PT ++D + G L + Sbjct: 878 ADNCEKVRGSSEGNLQGLDLYAPLFIGGVHDLS-ELPT-----YVDFKSGFR-GNLYGMA 930 Query: 1272 SSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA--PCYNGAECS 1329 F N+++ +S + + + S + G+ G E + C S PC NG C+ Sbjct: 931 IRFS--NQEYWRNLS--LLQTQGV---SERVEAGSNIG-NESYNECISQTPPCLNGGNCT 982 Query: 1330 DLWDTYICDCKEGHTGKDCADSTGP 1354 TY+C C G G C + P Sbjct: 983 RHAATYVCRCLPGWRGLYCGSRSIP 1007 Score = 37.5 bits (83), Expect = 0.15 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 7/71 (9%) Query: 1515 ADCMLSICPPYSKCVTSWDSS---TCTCEAGRVGPQC--VSACELGPCGAARCVPDQT-- 1567 A C+ + C C D C C +G G C +SAC PC RC+ + Sbjct: 686 APCVNNPCHNGGTCTPDGDDPHDYDCKCPSGYQGKSCTLISACVGDPCNGGRCIVSNSSQ 745 Query: 1568 PKGYSCACEPG 1578 P+ + C C G Sbjct: 746 PQNHVCLCPYG 756 Score = 34.7 bits (76), Expect = 1.1 Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S PC NG C D ++Y C C+ G +C Sbjct: 214 CASRPCLNGGLCVDGVNSYSCLCQPDINGNNC 245 Score = 34.3 bits (75), Expect = 1.4 Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 3/35 (8%) Query: 1317 CSSAPCYNGAECSDLWDT---YICDCKEGHTGKDC 1348 C + PC+NG C+ D Y C C G+ GK C Sbjct: 688 CVNNPCHNGGTCTPDGDDPHDYDCKCPSGYQGKSC 722 Score = 33.5 bits (73), Expect = 2.5 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 7/49 (14%) Query: 1310 CPEKRSRCSSA-PCYNGAEC-----SDLWDTYICDCKEGHTGKDCADST 1352 C E R+ C PC NG C SD Y C C EG TG++C++ T Sbjct: 376 CTE-RNLCEPVNPCANGGTCKRTVGSDGSAGYNCTCIEGFTGENCSEIT 423 Score = 33.1 bits (72), Expect = 3.3 Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 6/42 (14%) Query: 1315 SRCSSAPCYNGAECSDLW------DTYICDCKEGHTGKDCAD 1350 +RC PC NG C Y C C G+TG++C + Sbjct: 251 NRCQPNPCENGGTCDRTVGNDGSRSNYSCTCVSGYTGRNCTE 292 >SB_5020| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 687 Score = 43.2 bits (97), Expect = 0.003 Identities = 51/187 (27%), Positives = 64/187 (34%), Gaps = 34/187 (18%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574 C +KC S CTC G G +C + C G C ARC + T Y C Sbjct: 326 CDKNAKCNNIIGSYHCTCNPGFSGDGRECTDIDECVTGDHTCDKNARC--NNTIGSYHCT 383 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634 C PG++ C + +EC G CD + CN G HC+ N Sbjct: 384 CNPGFSGDGRECTDI--DEC--------VTGDHTCD----KNARCNNTIGSYHCRCNPGF 429 Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC---DACANAYAE 1683 EC G +N+ C G C C PG GR C D C Sbjct: 430 SGDGRECTDIDECVTGDHTCDKNARCNNTIGSYHCTCNPGFSGDGRECTDMDECVTGDHT 489 Query: 1684 VTPNSGC 1690 N+ C Sbjct: 490 CDKNAKC 496 Score = 34.3 bits (75), Expect = 1.4 Identities = 48/196 (24%), Positives = 65/196 (33%), Gaps = 32/196 (16%) Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELG--PCGA-AR 1561 C +C C +KC + S CTC G G C + C G C A+ Sbjct: 108 CSETDECSAGNHTCDKNAKCNNTIGSYHCTCNPGFSGDGRNCTDIDECVTGNHTCDKNAK 167 Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNK 1621 C + Y C C PG++ C + +EC G CD + CN Sbjct: 168 C--NNIIGSYHCMCNPGFSKDGRECTDI--DEC--------VTGDHTCD----KNARCNN 211 Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVIGRACD 1675 G HC N C G +N+ C G C C PG G + Sbjct: 212 IIGSYHCMCNPGFSGDGRNCTDIDECVTGDHTCDKNARCGNIIGSHHCICNPGFSGDGKN 271 Query: 1676 ACANAYAEVTPNSGCE 1691 C + VT + C+ Sbjct: 272 -CTDIDECVTGDHTCD 286 Score = 33.5 bits (73), Expect = 2.5 Identities = 46/187 (24%), Positives = 64/187 (34%), Gaps = 34/187 (18%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574 C ++C + S CTC G G +C + C G C A+C + + C Sbjct: 449 CDKNARCNNTIGSYHCTCNPGFSGDGRECTDMDECVTGDHTCDKNAKC--NNIIGSHHCT 506 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634 C PG++ CI+ +EC G CD + CN G HC N Sbjct: 507 CNPGFSGDGRECIDI--DEC--------VTGDHTCD----KNAKCNNIVGSHHCTCNPGF 552 Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVIG-----RACDACANAYAE 1683 EC G +N+ C G C C G G R D C Sbjct: 553 SGNGRECTDIDECGTGDHTCDKNARCNNTIGSYDCMCMSGFYGNSTRCRDIDECKKEKHH 612 Query: 1684 VTPNSGC 1690 +P++ C Sbjct: 613 CSPHAIC 619 >SB_37317| Best HMM Match : EGF_CA (HMM E-Value=6.6e-25) Length = 86 Score = 42.7 bits (96), Expect = 0.004 Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 8/74 (10%) Query: 1522 CPPY-SKCVTSWDSSTCTCEAGRVGP--QCVSACELGPCGAARCVPD-----QTPKGYSC 1573 C P S C + S TC+C AG G CV + GA C P T Y+C Sbjct: 12 CAPIGSSCTNNAGSFTCSCNAGYAGDGETCVEDIDECSSGAHTCAPSGSTCTNTVGSYTC 71 Query: 1574 ACEPGYTLTTSGCI 1587 AC GYT C+ Sbjct: 72 ACNVGYTGDGETCV 85 >SB_28272| Best HMM Match : EGF (HMM E-Value=2.6e-15) Length = 157 Score = 42.7 bits (96), Expect = 0.004 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 6/70 (8%) Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570 C S C + C D+S CTC G G C V C PC + C G Sbjct: 80 CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKPCGSSPCKNNSTCTNKDENSG 139 Query: 1571 YSCACEPGYT 1580 Y C C G+T Sbjct: 140 YDCTCSTGFT 149 Score = 41.5 bits (93), Expect = 0.009 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354 + +GT A + C S+PC N A C++ D Y C C G TG DC P Sbjct: 66 SSSGTCANSARVKP-CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKP 119 Score = 35.5 bits (78), Expect = 0.62 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 7/72 (9%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSACELGPC-GAARCVPDQTP 1568 C C ++ +C +SS+ TC + RV P C+ PC A C + Sbjct: 43 CTEEYICRVNFENNTHRCECPKESSSGTCANSARVKP-----CDSSPCQNNATCTNKEDN 97 Query: 1569 KGYSCACEPGYT 1580 GY+C C G+T Sbjct: 98 SGYNCTCSTGFT 109 Score = 34.3 bits (75), Expect = 1.4 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 2/45 (4%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECS--DLWDTYICDCKEGHTGKDC 1348 T + C + C S+PC N + C+ D Y C C G T DC Sbjct: 109 TGSDCETQVKPCGSSPCKNNSTCTNKDENSGYDCTCSTGFTESDC 153 Score = 33.5 bits (73), Expect = 2.5 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 8/65 (12%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 + + C C GFTG +CET + S C++ S C + E C+ +T Sbjct: 98 SGYNCTCSTGFTGSDCETQVKPCG------SSPCKNNSTCTNKDENS--GYDCTCSTGFT 149 Query: 1100 TAVCE 1104 + CE Sbjct: 150 ESDCE 154 >SB_20457| Best HMM Match : fn3 (HMM E-Value=5.1e-12) Length = 1114 Score = 42.7 bits (96), Expect = 0.004 Identities = 51/229 (22%), Positives = 85/229 (37%), Gaps = 20/229 (8%) Query: 1663 CHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPP 1722 C C PG +G N + + G D C + W RT G +T CP Sbjct: 652 CKCGPGFVG-------NGFLCRVESPGLSDK-DFCGPITTQNIKWSRTLKGQTDVTSCPK 703 Query: 1723 GSSGRATRTCDE---TKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVA 1779 +G A R C E +D W PD+ C + +++Q ++ E T V +VA Sbjct: 704 DVTGVARRKCKEQEPDQDASWDTPDLSECISEWALNIKEQ--ALDPSEAV--TSVASKVA 759 Query: 1780 ADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTIL 1839 T+ +Y D+ IL L E + + D+ + ++++ + IL Sbjct: 760 N--LTSVTRVEDIYPGDLYAVVDILGLLS--ERAGSSRSSVPQASTDFNKAVVQTASNIL 815 Query: 1840 NVEYEREWKRIREL-TGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIV 1887 + +W I A L+ D +A+S T+ +V Sbjct: 816 EAKTINKWSFIPPTKRKRQAGSLMSNLDNVALKMAQSSGSAITAMPNVV 864 >SB_37171| Best HMM Match : EGF (HMM E-Value=2.6e-15) Length = 186 Score = 42.7 bits (96), Expect = 0.004 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 6/70 (8%) Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570 C S C + C D+S CTC G G C V C PC + C G Sbjct: 80 CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKPCGSSPCKNNSTCTNKDENSG 139 Query: 1571 YSCACEPGYT 1580 Y C C G+T Sbjct: 140 YDCTCSTGFT 149 Score = 41.5 bits (93), Expect = 0.009 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354 + +GT A + C S+PC N A C++ D Y C C G TG DC P Sbjct: 66 SSSGTCANSARVKP-CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKP 119 Score = 35.9 bits (79), Expect = 0.47 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 3/66 (4%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECS--DLWDTYICDCKEGHTGKDC-ADSTGPPWRFGGDG 1362 T + C + C S+PC N + C+ D Y C C G T DC T +RF + Sbjct: 109 TGSDCETQVKPCGSSPCKNNSTCTNKDENSGYDCTCSTGFTESDCETQGTISKYRFNAET 168 Query: 1363 MLSFNP 1368 S P Sbjct: 169 GQSGEP 174 Score = 35.5 bits (78), Expect = 0.62 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 7/72 (9%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSACELGPC-GAARCVPDQTP 1568 C C ++ +C +SS+ TC + RV P C+ PC A C + Sbjct: 43 CTEEYICRVNFENNTHRCECPKESSSGTCANSARVKP-----CDSSPCQNNATCTNKEDN 97 Query: 1569 KGYSCACEPGYT 1580 GY+C C G+T Sbjct: 98 SGYNCTCSTGFT 109 Score = 33.5 bits (73), Expect = 2.5 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 8/65 (12%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 + + C C GFTG +CET + S C++ S C + E C+ +T Sbjct: 98 SGYNCTCSTGFTGSDCETQVKPCG------SSPCKNNSTCTNKDENS--GYDCTCSTGFT 149 Query: 1100 TAVCE 1104 + CE Sbjct: 150 ESDCE 154 >SB_31622| Best HMM Match : EGF (HMM E-Value=4.2e-09) Length = 39 Score = 42.7 bits (96), Expect = 0.004 Identities = 16/32 (50%), Positives = 19/32 (59%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C S PC NG C DL +Y CDC +G G +C Sbjct: 5 CLSTPCLNGGTCVDLVASYRCDCIKGFNGTNC 36 >SB_19665| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 491 Score = 42.7 bits (96), Expect = 0.004 Identities = 42/130 (32%), Positives = 54/130 (41%), Gaps = 14/130 (10%) Query: 1499 NRPTVRENVRDGCQSRADCMLSICPP-YSKCVTSWDSS-TCTCEAGRVGPQCVSACELGP 1556 N V E+V G ++ C CP S C DSS +C C G G +C E Sbjct: 111 NMADVSESVYQGFENV--CNNRPCPDDRSTCGIGTDSSHSCLCRPGFEGEKCSDIDECAV 168 Query: 1557 CGAARCVPD----QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDV 1611 G + C + T Y+C C+PGYT C + +EC G S C A C+ Sbjct: 169 SGDSPCDKNAECNNTVGSYTCTCKPGYTGDRKTC--NDIDECAIS--GDSPCDKNAECNN 224 Query: 1612 TRG-YHPHCN 1620 T G Y CN Sbjct: 225 TVGSYTCTCN 234 Score = 40.3 bits (90), Expect = 0.022 Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 18/116 (15%) Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQ--C--VSACELG---PCGA-ARCVPDQTPKGY 1571 S C ++C + S TCTC+ G G + C + C + PC A C + T Y Sbjct: 172 SPCDKNAECNNTVGSYTCTCKPGYTGDRKTCNDIDECAISGDSPCDKNAEC--NNTVGSY 229 Query: 1572 SCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCAC---DVTRGYHPHC 1619 +C C PGYT C + + + C G + C C T PHC Sbjct: 230 TCTCNPGYTGDGKTCDDVNECTTNPDICNGECTNYNGSYTCKCRDKSNTMSQAPHC 285 Score = 36.3 bits (80), Expect = 0.35 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 2/33 (6%) Query: 1320 APCYNGAECSDLWDTYICDCKEGHTG--KDCAD 1350 +PC AEC++ +Y C CK G+TG K C D Sbjct: 172 SPCDKNAECNNTVGSYTCTCKPGYTGDRKTCND 204 Score = 34.3 bits (75), Expect = 1.4 Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%) Query: 1320 APCYNGAECSDLWDTYICDCKEGHT--GKDCAD 1350 +PC AEC++ +Y C C G+T GK C D Sbjct: 214 SPCDKNAECNNTVGSYTCTCNPGYTGDGKTCDD 246 >SB_32719| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 604 Score = 42.3 bits (95), Expect = 0.005 Identities = 52/194 (26%), Positives = 64/194 (32%), Gaps = 28/194 (14%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKGYSC 1573 C+ S C CV S C C G C +S C PC C T +G+ C Sbjct: 196 CLPSPCRNNGTCVNIGASYKCNCPPEFYGKHCEALSKCTPNPCKNDGTCRDISTGRGFVC 255 Query: 1574 ACEPGYTLTTSGCIESG----KEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHC 1628 C Y C C G + AC GY HC + N C Sbjct: 256 YCSIAY--LGPNCDRKNLCHPDNPCKNGGTCKTDGSTVACHCKEGYLGSHCEQMN---FC 310 Query: 1629 KENHYKPEGTAECLP------CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682 N K +GT C P C C G +C+ +C+ P G C A Sbjct: 311 YGNPCKNKGT--CTPKLDGYECDC-PEGFYGKNCD-GVDRCYPNPCANGATC-----FNA 361 Query: 1683 EVTPNSGCEVVYDG 1696 E+T C V Y G Sbjct: 362 ELTYICQCPVRYMG 375 Score = 41.9 bits (94), Expect = 0.007 Identities = 46/181 (25%), Positives = 58/181 (32%), Gaps = 24/181 (13%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKGYSCACEPG 1578 C C T + C C+ G +G C ++ C PC C P GY C C G Sbjct: 278 CKNGGTCKTDGSTVACHCKEGYLGSHCEQMNFCYGNPCKNKGTCTPKL--DGYECDCPEG 335 Query: 1579 -YTLTTSGCIESGKEECPGG--WWGGSACGPCACDV----TRGYHPHC-----NKE--NG 1624 Y G C G + C C V R C N E NG Sbjct: 336 FYGKNCDGVDRCYPNPCANGATCFNAELTYICQCPVRYMGIRCRVDKCDRCDLNAECLNG 395 Query: 1625 KCHCKE----NHYKPEGTAE-CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 C C+ N +K T + C+P C G C C G G C+ + Sbjct: 396 TCECRSGFVGNGFKCTATEDPCIPNPCENGGICRPGHGGKVFDCSCPSGFDGMRCEVTKS 455 Query: 1680 A 1680 A Sbjct: 456 A 456 Score = 41.1 bits (92), Expect = 0.012 Identities = 18/44 (40%), Positives = 22/44 (50%) Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 G L E+ + C PC N C+ D Y CDC EG GK+C Sbjct: 298 GYLGSHCEQMNFCYGNPCKNKGTCTPKLDGYECDCPEGFYGKNC 341 Score = 39.5 bits (88), Expect = 0.038 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 7/63 (11%) Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061 C PCLN C+ + N +G + D V+F + F C CP+G+ G+NC+ ++ + Sbjct: 457 CKARPCLNGGICVDLT---NDNGTL-LDGVIF---LNTSDFRCVCPKGYAGINCDKLVLR 509 Query: 1062 ASC 1064 C Sbjct: 510 NPC 512 Score = 36.3 bits (80), Expect = 0.35 Identities = 35/144 (24%), Positives = 47/144 (32%), Gaps = 16/144 (11%) Query: 1575 CEPGYTLTTSGCIESG---KEECPGGWWGG-----SACGPCACDVTRGYHPHCNKENGKC 1626 C P C+ G K CP ++G S C P C C Sbjct: 196 CLPSPCRNNGTCVNIGASYKCNCPPEFYGKHCEALSKCTPNPCKNDGTCRDISTGRGFVC 255 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPGVIGRACDACANAYAEV 1684 +C + P + L C +C + +T CHC+ G +G C+ Y Sbjct: 256 YCSIAYLGPNCDRKNL-CHPDNPCKNGGTCKTDGSTVACHCKEGYLGSHCEQMNFCYGNP 314 Query: 1685 TPNSG-CEVVYDG----CPRSFAG 1703 N G C DG CP F G Sbjct: 315 CKNKGTCTPKLDGYECDCPEGFYG 338 Score = 36.3 bits (80), Expect = 0.35 Identities = 15/39 (38%), Positives = 16/39 (41%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C K PC NG C T C CKEG+ G C Sbjct: 266 CDRKNLCHPDNPCKNGGTCKTDGSTVACHCKEGYLGSHC 304 Score = 36.3 bits (80), Expect = 0.35 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 7/59 (11%) Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV-ARREGGILCQG 1091 RP + F C CP GF G+ CE +TK++C+ C +G CV + G L G Sbjct: 429 RPGHGGKVFDCSCPSGFDGMRCE--VTKSACK----ARPCLNGGICVDLTNDNGTLLDG 481 Score = 35.5 bits (78), Expect = 0.62 Identities = 15/33 (45%), Positives = 17/33 (51%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 RC PC NGA C + TYIC C + G C Sbjct: 346 RCYPNPCANGATCFNAELTYICQCPVRYMGIRC 378 Score = 32.7 bits (71), Expect = 4.4 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 10/75 (13%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS-----QCVARREG----GILCQGC 1092 + C CPEGF G NC+ + + +G+ C + QC R G C C Sbjct: 328 YECDCPEGFYGKNCDGV-DRCYPNPCANGATCFNAELTYICQCPVRYMGIRCRVDKCDRC 386 Query: 1093 SIDAAYTTAVCELRA 1107 ++A CE R+ Sbjct: 387 DLNAECLNGTCECRS 401 >SB_26949| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 92 Score = 42.3 bits (95), Expect = 0.005 Identities = 23/68 (33%), Positives = 41/68 (60%), Gaps = 4/68 (5%) Query: 394 DEDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 D+ N +L++ IT GN + F + N G+I + + LDF++ + Y L+VS DSG Sbjct: 2 DKSNAQLNFGITEGNVKNTFYV---NTEGVIYLNRSLDFEERKVYNLSVSVEDSGTPKRK 58 Query: 453 AMVQINIT 460 A+++ N++ Sbjct: 59 AVIEANVS 66 Score = 37.9 bits (84), Expect = 0.12 Identities = 16/55 (29%), Positives = 33/55 (60%), Gaps = 1/55 (1%) Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 +N+ + + I GN + F +++ G + L ++LD+E+ + Y L + +D G+P R Sbjct: 4 SNAQLNFGITEGNVKNTFYVNT-EGVIYLNRSLDFEERKVYNLSVSVEDSGTPKR 57 >SB_23501| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 585 Score = 42.3 bits (95), Expect = 0.005 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 8/76 (10%) Query: 1527 KCVTSWDSSTCTCEAGRV--GPQCVSA--CELGP--CGAARCVPDQTPKGYSCACEPGYT 1580 +CV + S C C G + G CV C + P CG A+CV TP Y C C G+ Sbjct: 15 RCVNTVGSFRCECPIGYMKNGVTCVDKDECMMTPNLCGEAKCV--NTPGSYVCKCNSGFE 72 Query: 1581 LTTSGCIESGKEECPG 1596 K+EC G Sbjct: 73 YNPQTKTCGDKDECKG 88 Score = 40.7 bits (91), Expect = 0.016 Identities = 51/190 (26%), Positives = 72/190 (37%), Gaps = 32/190 (16%) Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAG-RVGPQCVSACELGPC-GAAR----- 1561 C + +CM++ +C +KCV + S C C +G PQ + + C G ++ Sbjct: 38 CVDKDECMMTPNLCGE-AKCVNTPGSYVCKCNSGFEYNPQTKTCGDKDECKGQSQLCQFG 96 Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNK 1621 CV Y C C+PG+TL+ EC + CG C T G + +C Sbjct: 97 CV--NLIGSYRCGCQPGFTLSYYWNQCQDVNECQ-----TNPCGGAQCQNTLGSY-YCGC 148 Query: 1622 ENGKCHCKENHYKPEGTAECL----PCQCYAAGSENS--SCEAAT-----GQCHCRPGVI 1670 G N + EC PC Y + N SC + G HC Sbjct: 149 AQGNI-LAPNRRSCQDINECSMGINPCS-YGCNNNNGGFSCACPSGFYPIGDGHCLSS-F 205 Query: 1671 GRACDACANA 1680 G AC CA A Sbjct: 206 GEACYECALA 215 >SB_21594| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1075 Score = 42.3 bits (95), Expect = 0.005 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGD 1361 C + + C S PC NG C++ Y C C G TG +C TG RF D Sbjct: 504 CEDDINECQSNPCKNGGTCANGEHKYSCACAPGFTGTNC--DTGKLVRFTSD 553 Score = 35.5 bits (78), Expect = 0.62 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 1537 CTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLT 1582 C C G G +C ++ C+ PC + K YSCAC PG+T T Sbjct: 493 CHCPEGFSGDKCEDDINECQSNPCKNGGTCANGEHK-YSCACAPGFTGT 540 Score = 33.1 bits (72), Expect = 3.3 Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076 C CPEGF+G CE + + +G C +G Sbjct: 493 CHCPEGFSGDKCEDDINECQSNPCKNGGTCANG 525 >SB_33543| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 838 Score = 42.3 bits (95), Expect = 0.005 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 1275 QVKNKDFVGCISDFYID-HKFI--DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDL 1331 + K FVGC+ + ID HK L+ NG A +RC PC N C Sbjct: 338 EYKFPGFVGCMLNLRIDSHKITARHLSKQKYSNGIDATKCATSNRCFPNPCINRGTCWQD 397 Query: 1332 WDTYICDCKEGH-TGKDC 1348 W ++ CDC + GK C Sbjct: 398 WQSFYCDCSNTYFEGKRC 415 Score = 39.9 bits (89), Expect = 0.029 Identities = 38/158 (24%), Positives = 67/158 (42%), Gaps = 17/158 (10%) Query: 1393 MSIQLKSGLLHYSY---NGETMYLPMA-TLSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448 ++I+L SG+L Y NG L M L+DG WH + + ++ +T+D R+ + Sbjct: 254 LNIRLHSGVLMYDVLAPNGSKAELRMGENLNDGEWHSVNASIVPPNVQLTLDDRTRSKFL 313 Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGLLASDVGF--FEGCIQDVRIGTAQSLLNRPTVREN 1506 + + + ++ I AG A + F F GC+ ++RI + + R ++ Sbjct: 314 NLTSLLLDFSNKSRLKI-----FAGRGAREYKFPGFVGCMLNLRI-DSHKITARHLSKQK 367 Query: 1507 VRDG-----CQSRADCMLSICPPYSKCVTSWDSSTCTC 1539 +G C + C + C C W S C C Sbjct: 368 YSNGIDATKCATSNRCFPNPCINRGTCWQDWQSFYCDC 405 Score = 32.3 bits (70), Expect = 5.8 Identities = 12/35 (34%), Positives = 19/35 (54%) Query: 1180 GGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDD 1214 G K+E+ + N+ DG WH+V + + LDD Sbjct: 272 GSKAELRMGENLNDGEWHSVNASIVPPNVQLTLDD 306 >SB_32196| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1333 Score = 42.3 bits (95), Expect = 0.005 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 2/89 (2%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P+F +K Y + ED +V D+ I + A D IRY+I + +ID +G Sbjct: 141 PEFEQKEYEAEIREDAAVGDD--ILTVTALDRCSKHPDKIRYSIAEESDDELLTIDENNG 198 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236 + + K+L+ +S L ++A G S Sbjct: 199 RIKVAKSLESSAGKSLELTVQANKGADQS 227 Score = 40.7 bits (91), Expect = 0.016 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATD--ADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F +YE E+ ED G ++T+TA D + +++ Y I + +I NGR I Sbjct: 143 FEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSIAEESDDELLTIDENNGR--I 200 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 VA+ L+ + LTV A + G A + +T Sbjct: 201 KVAKSLESSAGKSLELTVQA-NKGADQSVAKAHVRVT 236 Score = 39.9 bits (89), Expect = 0.029 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 7/96 (7%) Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P FE Y A + EDA +G +L V+A D +I YS++ E D+ I Sbjct: 141 PEFEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSIAEE-------SDDELLTI 193 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 + G I K L+ LTV A G S++ Sbjct: 194 DENNGRIKVAKSLESSAGKSLELTVQANKGADQSVA 229 Score = 38.3 bits (85), Expect = 0.088 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 4/99 (4%) Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P F+Q+ Y A I EDA VG + V A D +I Y + ++ ++ ID +G Sbjct: 141 PEFEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSI-AEESDDELLTIDENNGR 199 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 I+ K+L+ + + +L A G S H+++ Sbjct: 200 IKVAKSLESSAGKSLELTVQANKGA---DQSVAKAHVRV 235 Score = 37.1 bits (82), Expect = 0.20 Identities = 18/50 (36%), Positives = 29/50 (58%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 P FE ++YEA +RE A+ G +LT+ A D+ ++ Y+I + D L Sbjct: 141 PEFEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSIAEESDDEL 190 >SB_44376| Best HMM Match : EGF_CA (HMM E-Value=7.8e-22) Length = 84 Score = 41.9 bits (94), Expect = 0.007 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 6/66 (9%) Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRV--GPQCVSACELGPCGAARC----VPDQTPKGYSC 1573 S C P +KC+ S C C G + G C E G A C TP + C Sbjct: 10 SPCDPNAKCINMMGSYACGCNEGFLGDGTNCTDVDECSTPGVATCSNLATCINTPGSFKC 69 Query: 1574 ACEPGY 1579 C+PGY Sbjct: 70 ECKPGY 75 >SB_34553| Best HMM Match : F5_F8_type_C (HMM E-Value=8.3e-22) Length = 667 Score = 41.9 bits (94), Expect = 0.007 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 8/68 (11%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 T +TC CP +TG CET + D S C++G C + + C+ +AYT Sbjct: 236 TGYTCTCPSEYTGTECETQVQPC------DSSPCKNGGACANKADNS--GYTCACASAYT 287 Query: 1100 TAVCELRA 1107 CE +A Sbjct: 288 GIECESQA 295 Score = 39.9 bits (89), Expect = 0.029 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 4/49 (8%) Query: 1536 TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 TCTC + G +C V C+ PC C GY+CAC YT Sbjct: 239 TCTCPSEYTGTECETQVQPCDSSPCKNGGACANKADNSGYTCACASAYT 287 Score = 39.1 bits (87), Expect = 0.050 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 2/47 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354 C + C S+PC NG C++ D Y C C +TG +C P Sbjct: 251 CETQVQPCDSSPCKNGGACANKADNSGYTCACASAYTGIECESQAHP 297 >SB_33149| Best HMM Match : DSL (HMM E-Value=5.60519e-45) Length = 443 Score = 41.9 bits (94), Expect = 0.007 Identities = 31/119 (26%), Positives = 46/119 (38%), Gaps = 8/119 (6%) Query: 1570 GYSCACEPGYTLTTS-GCIES-GKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627 G C C P + C E+ G++ C GW+G + C+ H +CN + G Sbjct: 152 GPECDCRPRLDASAGYTCNETTGQKICYPGWYGRNCNVACSPRNDSTGHYNCNADTGAKE 211 Query: 1628 CKENHYKPEGTAECLP----CQCYAAGSENSSCEAATGQCH--CRPGVIGRACDACANA 1680 C E+ + C+P C A G+ QCH C+P I C + A Sbjct: 212 CLESWIGEQCDVYCVPDNQTHSCLANGTRKCQQHWYGQQCHVFCQPRPIQYTCQSTTGA 270 Score = 40.3 bits (90), Expect = 0.022 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 10/108 (9%) Query: 1586 CIESGKEECPGGWWGGSACGPCAC---DVTRGYHPHCNKENGKCHCKENHYKPEGTAECL 1642 C +G C GW+ C D T Y C+ + G C PE +C Sbjct: 103 CDVTGSRVCLPGWYPREQCETLCIPHNDSTASYT--CDSQTGSKTCLSGWSGPE--CDCR 158 Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690 P +AG +C TGQ C PG GR C+ + + T + C Sbjct: 159 PRLDASAGY---TCNETTGQKICYPGWYGRNCNVACSPRNDSTGHYNC 203 Score = 38.3 bits (85), Expect = 0.088 Identities = 36/155 (23%), Positives = 51/155 (32%), Gaps = 14/155 (9%) Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTS-GC 1586 C++ W C C R+ C G C P + + AC P T C Sbjct: 146 CLSGWSGPECDCRP-RLDASAGYTCN-ETTGQKICYPGWYGRNCNVACSPRNDSTGHYNC 203 Query: 1587 -IESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ 1645 ++G +EC W G C D H NG C+++ Y + C P Sbjct: 204 NADTGAKECLESWIGEQCDVYCVPD----NQTHSCLANGTRKCQQHWYGQQCHVFCQPRP 259 Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 +C++ TG C G G C A Sbjct: 260 I------QYTCQSTTGAKVCSQGWYGEDCSTFCKA 288 Score = 36.7 bits (81), Expect = 0.27 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 12/109 (11%) Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA-CANAYAEVTP 1686 C ++Y P T C+P S + +C+ TG CRPG G C C + +V+ Sbjct: 9 CTRDYYGPNCTTHCIPRD---GTSGHYTCDLKTGGRVCRPGWHGPQCRVYCISRDDDVSG 65 Query: 1687 NSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDET 1735 + C+ G W +GV T C P ++ A CD T Sbjct: 66 HFTCQT---GTGLKICLANW-----YGVLCKTYCAPINNSDAGYNCDVT 106 Score = 34.7 bits (76), Expect = 1.1 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 12/112 (10%) Query: 1575 CEP--GYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632 C+P TL C + G C W+G C H C +G+ C E+ Sbjct: 320 CKPHRNSTLGYYRCDDHGNPVCERDWYGTKCTVYCRPRDDEEGHYSCGAVDGRRVCLEDW 379 Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCH--CR---PGVIGRACDACAN 1679 Y T C+ A + +C+ TGQ H CR GV+G + A+ Sbjct: 380 YGENCTVHCV-----ADKEGHFTCDGKTGQRHRLCRLLAAGVLGDGLGSLAH 426 >SB_50993| Best HMM Match : EGF (HMM E-Value=3.4e-19) Length = 220 Score = 41.5 bits (93), Expect = 0.009 Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 C+ APC N C++L D Y C CK+G TGK+C Sbjct: 120 CAEAPCQNEGLCANLPDYSDYTCTCKKGFTGKNC 153 Score = 40.7 bits (91), Expect = 0.016 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 8/85 (9%) Query: 1513 SRADCMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQ 1566 ++ C + C C D S TCTC+ G G C ++AC+ PC C Sbjct: 116 AKEPCAEAPCQNEGLCANLPDYSDYTCTCKKGFTGKNCEKEMTACDSQPCANGGACKATA 175 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGK 1591 GY CAC G+ C GK Sbjct: 176 EQPGYICACLSGF--EGDACQNKGK 198 Score = 37.9 bits (84), Expect = 0.12 Identities = 13/39 (33%), Positives = 23/39 (58%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQ 1078 + +TC C +GFTG NCE +T + +G C++ ++ Sbjct: 138 SDYTCTCKKGFTGKNCEKEMTACDSQPCANGGACKATAE 176 Score = 35.5 bits (78), Expect = 0.62 Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348 C ++ + C S PC NG C + YIC C G G C Sbjct: 153 CEKEMTACDSQPCANGGACKATAEQPGYICACLSGFEGDAC 193 >SB_47717| Best HMM Match : EGF (HMM E-Value=1.9e-29) Length = 214 Score = 41.5 bits (93), Expect = 0.009 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 14/122 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C + C C+ + TC C+ G +G +C ++ C PC A+C Q G+ Sbjct: 10 ECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRCHAVINKCLFNPCKNGAKCQTLQ-DGGH 68 Query: 1572 SCACEPGY--TLTTSGCIESGKEECPGGWWGGSACG----PCACDVTRGY-HPHCNKENG 1624 C CE G+ +L E + + P G G CAC++ GY CN Sbjct: 69 RCLCEKGFKGSLCEVNVNECNETQSPCSEHGACIDGVNSYTCACNL--GYTGSTCNVTVN 126 Query: 1625 KC 1626 C Sbjct: 127 DC 128 Score = 39.5 bits (88), Expect = 0.038 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 9/67 (13%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098 + FTC+C +GF G C ++ K C + C++G++C ++GG C + + Sbjct: 26 INGFTCKCQDGFIGDRCHAVINK--CLFNP----CKNGAKCQTLQDGG---HRCLCEKGF 76 Query: 1099 TTAVCEL 1105 ++CE+ Sbjct: 77 KGSLCEV 83 Score = 34.7 bits (76), Expect = 1.1 Identities = 14/41 (34%), Positives = 18/41 (43%) Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 A C C S PCY C D + + C C++G G C Sbjct: 2 ATCDIDIDECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRC 42 Score = 32.7 bits (71), Expect = 4.4 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348 C ++C PC NGA+C L D + C C++G G C Sbjct: 42 CHAVINKCLFNPCKNGAKCQTLQDGGHRCLCEKGFKGSLC 81 >SB_52863| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 575 Score = 41.1 bits (92), Expect = 0.012 Identities = 37/134 (27%), Positives = 49/134 (36%), Gaps = 17/134 (12%) Query: 1509 DGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQ 1566 D C +C L + C S CV ++ + C C G G +AC C A CV Sbjct: 31 DKCPDVNECRLGLDSCHYNSTCVNTYGTYHCICNPGYTG-DGKTACN-KTCYPA-CVHGT 87 Query: 1567 TPKGYSCAC-----EPGYTLTTSGCIESGKEECPGGWWGGSACGPCAC----DVTRGYHP 1617 Y C C EP L + + C C C DVT G Sbjct: 88 CNSNYLCDCDLGCLEPTVRLIVGVTDTAHVTKASASVTSAKGCKACDCNGHGDVTLGV-- 145 Query: 1618 HCNKENGKCHCKEN 1631 C++ G+C CK+N Sbjct: 146 -CDRMTGQCFCKDN 158 Score = 40.3 bits (90), Expect = 0.022 Identities = 43/165 (26%), Positives = 56/165 (33%), Gaps = 14/165 (8%) Query: 1549 VSACELG--PCGA-ARCVPDQTPKGYSCACEPGYTLT-TSGCIESGKEECPGGWWGGSAC 1604 V+ C LG C + CV T Y C C PGYT + C ++ C G + Sbjct: 36 VNECRLGLDSCHYNSTCV--NTYGTYHCICNPGYTGDGKTACNKTCYPACVHGTCNSNYL 93 Query: 1605 GPCACDVTRGYHPHCNKENG---KCHCKENHYKPEGTAECLPCQCYAAGSENSS-CEAAT 1660 C CD+ P G H + C C C G C+ T Sbjct: 94 --CDCDLGC-LEPTVRLIVGVTDTAHVTKASASVTSAKGCKACDCNGHGDVTLGVCDRMT 150 Query: 1661 GQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGV 1705 GQC C+ G C+ C + P G Y+ RS V Sbjct: 151 GQCFCKDNTEGLNCERCKSGLVG-NPRYGGRCYYECKSRSILTNV 194 Score = 36.3 bits (80), Expect = 0.35 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%) Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674 C C + P+ T P C S + SC +A+G C C PG G C Sbjct: 348 CRCASDWTGPDCTIRVCPNNC----SGHGSCNSASGLCTCAPGYAGTDC 392 Score = 32.3 bits (70), Expect = 5.8 Identities = 18/62 (29%), Positives = 23/62 (37%), Gaps = 5/62 (8%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC-VSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580 C +CV + C C + GP C + C G C + G C C PGY Sbjct: 333 CHGNRRCVMTSQGEACRCASDWTGPDCTIRVCPNNCSGHGSC---NSASGL-CTCAPGYA 388 Query: 1581 LT 1582 T Sbjct: 389 GT 390 >SB_47423| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 855 Score = 41.1 bits (92), Expect = 0.012 Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 12/91 (13%) Query: 1129 LKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITV- 1187 + +FAT G+++++ ++ D + +EL +G +R SF LG G+ IT Sbjct: 299 IAFRFATGNPDGVIVHSSMFD---DHVVVEL-----SKGF---VRVSFDLGQGRLNITSR 347 Query: 1188 EGNVGDGSWHTVEIEYFNRTITMILDDCDKV 1218 EG + DG+WH+V I R +T+ LD +V Sbjct: 348 EGCLHDGTWHSVTIHRKRRRVTLDLDKQKRV 378 Score = 32.3 bits (70), Expect = 5.8 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 6/77 (7%) Query: 1271 PSSF-QVKNKDFVGCISDFYIDHKFIDLNSYV-ADNGTLAGCPEKRSRCSSAPCYNGAEC 1328 P++F Q FVGC + + + NGT GC + C+ C NG +C Sbjct: 663 PTAFWQSMQHGFVGCTRGMKYGYLGKESRPKINRTNGTRVGCG---NACAVLKCRNGGKC 719 Query: 1329 SDLWDTYICDCK-EGHT 1344 + CDC+ GHT Sbjct: 720 VNRIIVAECDCRGTGHT 736 >SB_47176| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 471 Score = 41.1 bits (92), Expect = 0.012 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 34/187 (18%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574 C +KC + S C C G G +C + C G C ARC + T Y C Sbjct: 71 CDKNAKCNNTIGSYHCMCNPGFSGDGRECTDIDECVTGDHTCDKNARC--NNTIGSYHCT 128 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634 C PG++ C + +EC A G CD + CN G HC+ N Sbjct: 129 CNPGFSGDGRNCTDI--DEC--------ATGDHTCD----KNAKCNNTIGSYHCRCNPGF 174 Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC---DACANAYAE 1683 C G +N+ C G C C PG GR C D C Sbjct: 175 SGDGRNCTDIDECVTGDHTCDKNARCNNIIGSYHCTCNPGFSGDGRNCTDIDECVTGDHT 234 Query: 1684 VTPNSGC 1690 N+ C Sbjct: 235 CDKNAKC 241 Score = 37.1 bits (82), Expect = 0.20 Identities = 52/188 (27%), Positives = 67/188 (35%), Gaps = 36/188 (19%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELG--PCGA-ARCVPDQTPKGYSCA 1574 C +KC + S CTC G G +C + C G C A+C + Y C Sbjct: 235 CDKNAKCNNTIGSYHCTCNPGFSGDGRECTDIDECVTGDHTCDKNAKC--NNIIGSYHCM 292 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDVTRG-YHPHCN---KENGKCHCK 1629 C PG++ C + +EC G C A C T G YH CN NG+ C Sbjct: 293 CNPGFSGNGRECTDI--DECV---TGDHTCDKNARCGNTIGSYHCTCNPGFSGNGR-ECT 346 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVI--GRAC---DACANAYA 1682 + G C +N+ C G C C PG GR C D C Sbjct: 347 DTDECVTGDHTC---------DKNARCGNTIGSYHCTCNPGFSGNGRECTDIDECVTGDY 397 Query: 1683 EVTPNSGC 1690 N+ C Sbjct: 398 TCDKNAKC 405 >SB_41795| Best HMM Match : EGF (HMM E-Value=8.7e-11) Length = 83 Score = 41.1 bits (92), Expect = 0.012 Identities = 15/36 (41%), Positives = 20/36 (55%) Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 + S CS PC NG C++ Y C C EG +G +C Sbjct: 43 RTSNCSPNPCQNGGVCTETATGYTCQCLEGFSGVNC 78 Score = 36.7 bits (81), Expect = 0.27 Identities = 13/17 (76%), Positives = 15/17 (88%) Query: 1040 TSFTCQCPEGFTGVNCE 1056 T +TCQC EGF+GVNCE Sbjct: 63 TGYTCQCLEGFSGVNCE 79 >SB_32588| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1135 Score = 41.1 bits (92), Expect = 0.012 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 14/91 (15%) Query: 1129 LKLKFATQTTSGLLLYNGRYNERH-DFLALELVSSEAGRGGGPGLRFSFSLGGGKS---- 1183 ++L+F T +GLLL+ E + D+ +EL+ G LRF+ SLG + Sbjct: 51 IELQFRTIQPNGLLLHGSSSGEEYGDYFTIELI--------GGKLRFAISLGRRQGIDDM 102 Query: 1184 -EITVEGNVGDGSWHTVEIEYFNRTITMILD 1213 +T+ + D +HTV IE+ NR + + LD Sbjct: 103 VNMTLGDGLADNKFHTVLIEHNNREVWLFLD 133 Score = 39.5 bits (88), Expect = 0.038 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 11/86 (12%) Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTL-AGCPEKR 1314 LD+ G L IGG ++ N FVGCI F I+ + ++L D + GC Sbjct: 759 LDVVGNLFIGGYMR-----EMMN-GFVGCIRGFTINGEVLNLARLSKDFDYVNEGC---Y 809 Query: 1315 SRCSS-APCYNGAECSDLWDTYICDC 1339 S C++ C GA C+D ++ Y CDC Sbjct: 810 SACNNETQCKGGARCTDDYNIYKCDC 835 Score = 35.9 bits (79), Expect = 0.47 Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 16/125 (12%) Query: 1416 ATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLL 1475 A L+ G WH +E + +G I+V ++ + P A+ Q +IG + IGG Sbjct: 293 APLNTGMWHHVEFE-IGP-IAVWINVDKMVDMRPPSADLPQNFFIGSVQIGG-------- 342 Query: 1476 ASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDG-CQSRADCMLSICPPYSKCVTSWDS 1534 F GC+ ++ + + + E + G C C ++C SKC+ + Sbjct: 343 -----DFVGCVLNIELNGVKFDPKSLSPTEYIEVGTCHITDFCFPTVCQHGSKCIQDGKT 397 Query: 1535 STCTC 1539 C C Sbjct: 398 FGCDC 402 Score = 32.3 bits (70), Expect = 5.8 Identities = 17/64 (26%), Positives = 25/64 (39%) Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339 DFVGC+ + ++ D S G C C +G++C T+ CDC Sbjct: 343 DFVGCVLNIELNGVKFDPKSLSPTEYIEVGTCHITDFCFPTVCQHGSKCIQDGKTFGCDC 402 Query: 1340 KEGH 1343 H Sbjct: 403 LNTH 406 >SB_14770| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 41 Score = 41.1 bits (92), Expect = 0.012 Identities = 18/41 (43%), Positives = 26/41 (63%) Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 +A DGG PP +ST V I++ D ND+PPV + + +SE Sbjct: 1 MAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 41 Score = 39.5 bits (88), Expect = 0.038 Identities = 18/40 (45%), Positives = 24/40 (60%) Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 A+DGG P L+ TT V I V D NDN PV + + ++ E Sbjct: 2 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 41 Score = 39.1 bits (87), Expect = 0.050 Identities = 17/40 (42%), Positives = 25/40 (62%) Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 AQDGG P ++TT + I + D NDN P ++ + S+SE Sbjct: 2 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 41 >SB_7289| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 278 Score = 41.1 bits (92), Expect = 0.012 Identities = 48/183 (26%), Positives = 64/183 (34%), Gaps = 30/183 (16%) Query: 1522 CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELG--PCGA-ARCVPDQTPKGYSCA 1574 C +KC + S CTC G G C + C G C A+C + T Y C Sbjct: 102 CDKNAKCNNTIGSYHCTCNPGFSGGGRNCTDIDECVTGDHTCDKNAKC--NNTIGSYHCM 159 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634 C PG++ C + +EC G CD + CN G HC N Sbjct: 160 CNPGFSGDGRECTDI--DEC--------VTGDHTCD----KNARCNNTIGSYHCMCNPGF 205 Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVIGRACDACANAYAEVTPNS 1688 EC G +N+ C G C C PG G + C + VT + Sbjct: 206 SGNGRECTDIDECVTGDHTCDKNARCNNTIGSYHCMCNPGFSGNGRE-CTDIDECVTGDH 264 Query: 1689 GCE 1691 C+ Sbjct: 265 TCD 267 Score = 33.1 bits (72), Expect = 3.3 Identities = 38/142 (26%), Positives = 47/142 (33%), Gaps = 27/142 (19%) Query: 1560 ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC 1619 ARC + T Y C C PG++ C + +EC G CD + C Sbjct: 24 ARC--NNTIGSYHCTCNPGFSGDGINCTDI--DEC--------VTGDHTCD----KNAKC 67 Query: 1620 NKENGKCHCKENHYKPEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--G 1671 N G HC N EC G +N+ C G C C PG G Sbjct: 68 NNTIGLYHCMCNPGFSGDGRECTDIDECVTGDHTCDKNAKCNNTIGSYHCTCNPGFSGGG 127 Query: 1672 RAC---DACANAYAEVTPNSGC 1690 R C D C N+ C Sbjct: 128 RNCTDIDECVTGDHTCDKNAKC 149 >SB_4732| Best HMM Match : EGF (HMM E-Value=2.4e-10) Length = 57 Score = 41.1 bits (92), Expect = 0.012 Identities = 14/32 (43%), Positives = 21/32 (65%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S+PC N A+C D ++Y C+C G G +C Sbjct: 5 CASSPCNNNAKCIDTKESYRCECLPGFQGANC 36 Score = 39.5 bits (88), Expect = 0.038 Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 4/52 (7%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563 DC S C +KC+ + +S C C G G C V C+ PC GAA CV Sbjct: 4 DCASSPCNNNAKCIDTKESYRCECLPGFQGANCDKEVDECDKQPCFGAATCV 55 >SB_57080| Best HMM Match : EGF_CA (HMM E-Value=1.4013e-43) Length = 360 Score = 41.1 bits (92), Expect = 0.012 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 1314 RSRCSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADST 1352 +S C S PC +GA C + YIC C G+TGK C T Sbjct: 107 KSDCISRPCQHGATCLAQYPCTAYICSCTPGYTGKHCETDT 147 Score = 35.5 bits (78), Expect = 0.62 Identities = 35/121 (28%), Positives = 47/121 (38%), Gaps = 10/121 (8%) Query: 1550 SACELGPCG-AARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA 1608 S C PC A C+ Y C+C PGY T C E+ EC G S C Sbjct: 108 SDCISRPCQHGATCLAQYPCTAYICSCTPGY--TGKHC-ETDTNECADGSHTCSINAACT 164 Query: 1609 CDVTRGYHPHCNK-ENGKCH-CKENHYKPEGTAEC-LPCQC-YAAGSENSSCEAA-TGQC 1663 + + CN G H C++ + +G+ C + C GS +C A TG Sbjct: 165 -NTVGSFTCACNAGYTGNGHTCQDTNECADGSHTCSINAACTNTVGSFTCACNAGYTGNG 223 Query: 1664 H 1664 H Sbjct: 224 H 224 Score = 34.3 bits (75), Expect = 1.4 Identities = 11/21 (52%), Positives = 15/21 (71%) Query: 1037 YPVTSFTCQCPEGFTGVNCET 1057 YP T++ C C G+TG +CET Sbjct: 125 YPCTAYICSCTPGYTGKHCET 145 Score = 33.1 bits (72), Expect = 3.3 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 11/83 (13%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP----QCVSACELG--PCGA-ARCVPDQTPKGYSCA 1574 C + C + S TC C AG G Q + C G C A C T ++CA Sbjct: 157 CSINAACTNTVGSFTCACNAGYTGNGHTCQDTNECADGSHTCSINAACT--NTVGSFTCA 214 Query: 1575 CEPGYTLTTSGCIESGKEECPGG 1597 C GYT C ++ EC G Sbjct: 215 CNAGYTGNGHTCQDT--NECADG 235 Score = 32.7 bits (71), Expect = 4.4 Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 11/79 (13%) Query: 1511 CQSRADCM--LSICPPYSKCVTSWDSSTCTCEAGRVGP----QCVSACELGP--CGA-AR 1561 CQ +C C + C + S TC C AG G Q + C G C A Sbjct: 185 CQDTNECADGSHTCSINAACTNTVGSFTCACNAGYTGNGHTCQDTNECADGSHTCSINAA 244 Query: 1562 CVPDQTPKGYSCACEPGYT 1580 C T ++CAC GYT Sbjct: 245 CT--NTVGSFTCACNAGYT 261 >SB_41915| Best HMM Match : F5_F8_type_C (HMM E-Value=9.1e-13) Length = 317 Score = 41.1 bits (92), Expect = 0.012 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 3/59 (5%) Query: 1300 YVADNGTLAGCPEKRSRCSSA-PCYNGAECSD--LWDTYICDCKEGHTGKDCADSTGPP 1355 Y AD+ L CS PC N A C + + Y C C+EG+TG+ C D PP Sbjct: 110 YTADSVYLEHLSRPAGSCSGGWPCSNKATCVNVPMMPGYKCYCQEGYTGELCQDCKSPP 168 >SB_15410| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1147 Score = 41.1 bits (92), Expect = 0.012 Identities = 55/220 (25%), Positives = 79/220 (35%), Gaps = 35/220 (15%) Query: 1492 GTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV----GPQ 1547 G Q + NR C +C++ C + S C C AG G Sbjct: 234 GGYQCICNRGFESTADMKDCVDINECLVDNGRCSEMCNNTLGSYLCDCGAGFALQPDGRT 293 Query: 1548 C--VSACELGP--CGAARCVPDQTPKGYSCACEPGY--TLTTSGCIESGKEECPGGWWGG 1601 C + C P CG + GY C C GY ++ + CI+ +EC Sbjct: 294 CRDIDECMERPDVCGPGNTC-NNIEGGYYCTCGKGYKQSVDSRSCIDV--DECQED---P 347 Query: 1602 SACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP---CQC-YAAGSENSSCE 1657 C C T G + +C C + + +GT C+ CQ A EN+ C Sbjct: 348 RLCTNGVCRNTPG--------SFECLCAKGYAIAKGTTACVDVNECQTGQAMCHENARCA 399 Query: 1658 AATG--QCHCRPGVI--GRAC---DACANAYAEVTPNSGC 1690 G +C C+PG I G +C D C A+ + C Sbjct: 400 NLVGSYRCECKPGFIGDGSSCTDVDECTTGIAQCSEQGTC 439 Score = 37.1 bits (82), Expect = 0.20 Identities = 54/227 (23%), Positives = 72/227 (31%), Gaps = 39/227 (17%) Query: 1492 GTAQSLLNRPTVRENVRDGCQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAG-RVGPQ- 1547 GT + + N+ R C+ +C +S +C C + + C C G R P Sbjct: 110 GTFECICNQGYGLTADRMDCEDIDECSISAGLCGN-GTCTNTPGAFRCDCNPGFRNAPMM 168 Query: 1548 ---CVSA--CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGS 1602 C+ C+ PC C T Y C C G L G K EC S Sbjct: 169 MEICIDIDECDHNPCADGTCY--NTMGSYKCVCPDGMELMKDGVSCEDKNEC-------S 219 Query: 1603 ACGPCACDVTRGYHPHCNKENG--KCHCKENHYKPEGTAECLPC-QCYA-AGSENSSCEA 1658 G C H C NG +C C +C+ +C G + C Sbjct: 220 DPGVCV-------HGRCENFNGGYQCICNRGFESTADMKDCVDINECLVDNGRCSEMCNN 272 Query: 1659 ATGQ--CHCRPGVI----GRAC---DACANAYAEVTPNSGCEVVYDG 1696 G C C G GR C D C P + C + G Sbjct: 273 TLGSYLCDCGAGFALQPDGRTCRDIDECMERPDVCGPGNTCNNIEGG 319 Score = 35.9 bits (79), Expect = 0.47 Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%) Query: 1300 YVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH--TGKDCAD 1350 Y GT A + A C+ A C++L +Y C+CK G G C D Sbjct: 370 YAIAKGTTACVDVNECQTGQAMCHENARCANLVGSYRCECKPGFIGDGSSCTD 422 Score = 34.3 bits (75), Expect = 1.4 Identities = 41/154 (26%), Positives = 55/154 (35%), Gaps = 17/154 (11%) Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCI 1587 CV + S C C AG +AC RC T G CE + L G Sbjct: 11 CVNTPGSYRCECSAGLTLDSIQNACV--DLRKDRCYMTITESG----CEKPFGL---GLY 61 Query: 1588 ESGKEECPGGWWGGSACG-PCA-CDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ 1645 + K++C G + G PC C + CN G C +GT EC+ Q Sbjct: 62 K--KDDCCCSAVGAAGWGTPCQECPLQNTDINECNTWQGLCR-NGRCVNKQGTFECICNQ 118 Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679 Y ++ CE +C G+ G C N Sbjct: 119 GYGLTADRMDCE-DIDECSISAGLCGNG--TCTN 149 Score = 33.5 bits (73), Expect = 2.5 Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 7/74 (9%) Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC--GAARCVPD----QTPKGYSC 1573 ++C ++C S C C+ G +G S ++ C G A+C TP + C Sbjct: 390 AMCHENARCANLVGSYRCECKPGFIGDGS-SCTDVDECTTGIAQCSEQGTCVNTPGSHRC 448 Query: 1574 ACEPGYTLTTSGCI 1587 C GYT C+ Sbjct: 449 VCHEGYTGDGITCV 462 >SB_48923| Best HMM Match : EGF_CA (HMM E-Value=3.2e-27) Length = 83 Score = 40.7 bits (91), Expect = 0.016 Identities = 29/80 (36%), Positives = 38/80 (47%), Gaps = 11/80 (13%) Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELG--PCGA-ARCVPDQ 1566 +C L+I CP CV + S TC C+ G V C + C LG C A A CV Sbjct: 4 ECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCV--N 61 Query: 1567 TPKGYSCACEPGYTLTTSGC 1586 Y+C C+ G+TL + C Sbjct: 62 NDGSYTCRCKRGFTLVNNTC 81 >SB_41903| Best HMM Match : HRM (HMM E-Value=0.00061) Length = 139 Score = 40.7 bits (91), Expect = 0.016 Identities = 27/100 (27%), Positives = 39/100 (39%), Gaps = 11/100 (11%) Query: 1663 CHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPP 1722 C C PG +G N + + G D C + W RT G +T CP Sbjct: 48 CKCGPGFVG-------NGFLCRVESPGLSDK-DFCGPITTQNIKWSRTLKGQTDVTSCPK 99 Query: 1723 GSSGRATRTCDE---TKDVPWQDPDMFNCTTATFYQLRKQ 1759 +G A R C E +D W PD+ C + +++Q Sbjct: 100 DVTGVARRKCKEQEPDQDASWDTPDLSECISEWALNIKEQ 139 >SB_39963| Best HMM Match : EGF (HMM E-Value=1.4e-13) Length = 3035 Score = 40.7 bits (91), Expect = 0.016 Identities = 14/35 (40%), Positives = 22/35 (62%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 C+ PC NG +C + D Y+C C G+TG +C ++ Sbjct: 160 CALFPCKNGGQCVNKDDGYLCLCPPGNTGDECQET 194 Score = 37.1 bits (82), Expect = 0.20 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 10/78 (12%) Query: 1507 VRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARC 1562 +++ CQ+ C C P V D C C+ G C + C L PC +C Sbjct: 116 IKNKCQTPGLCKNGTCYP----VYETDDFRCECKLNFSGRHCEIAIKDCALFPCKNGGQC 171 Query: 1563 VPDQTPKGYSCACEPGYT 1580 V GY C C PG T Sbjct: 172 V--NKDDGYLCLCPPGNT 187 Score = 36.3 bits (80), Expect = 0.35 Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 7/55 (12%) Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILC 1089 P+Y F C+C F+G +CE + C + C++G QCV ++ G LC Sbjct: 133 PVYETDDFRCECKLNFSGRHCEIAI--KDCAL----FPCKNGGQCV-NKDDGYLC 180 >SB_39510| Best HMM Match : VWA (HMM E-Value=0) Length = 705 Score = 40.7 bits (91), Expect = 0.016 Identities = 14/46 (30%), Positives = 23/46 (50%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355 C C + PC +G C++ +Y C+C G+ GK+C + P Sbjct: 74 CETGIDECLNLPCKHGGTCNNKGGSYSCECSTGYVGKNCKQNFTDP 119 Score = 40.3 bits (90), Expect = 0.022 Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 +C++ PC N C+ ++ + C C G GKDC+ Sbjct: 4 KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 37 Score = 38.7 bits (86), Expect = 0.066 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYS 1572 C S C C+ S+ S TC C+ G G C + C PC C + YS Sbjct: 43 CKSSPCNKNQNCINSFGSFTCVCKDGFKGDNCETGIDECLNLPCKHGGTC--NNKGGSYS 100 Query: 1573 CACEPGY 1579 C C GY Sbjct: 101 CECSTGY 107 Score = 36.3 bits (80), Expect = 0.35 Identities = 12/39 (30%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C +C S+PC C + + ++ C CK+G G +C Sbjct: 36 CSLDVDKCKSSPCNKNQNCINSFGSFTCVCKDGFKGDNC 74 Score = 32.7 bits (71), Expect = 4.4 Identities = 12/17 (70%), Positives = 13/17 (76%) Query: 1041 SFTCQCPEGFTGVNCET 1057 SFTC C +GF G NCET Sbjct: 60 SFTCVCKDGFKGDNCET 76 Score = 32.3 bits (70), Expect = 5.8 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC--ADSTGPPWRFGGDG 1362 C+ PC NG C Y C C G TG +C A +G F DG Sbjct: 302 CTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETACKSGIDLVFAVDG 350 Score = 31.9 bits (69), Expect = 7.6 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 1517 CMLSICPPYSKCVTSWDSS-TCTCEAGRVGPQCVSACELG 1555 C + C C+ S S TCTC G G C +AC+ G Sbjct: 302 CTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETACKSG 341 >SB_33920| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1278 Score = 40.7 bits (91), Expect = 0.016 Identities = 47/163 (28%), Positives = 65/163 (39%), Gaps = 25/163 (15%) Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPC-------ACDVTRGYHPHC--NKEN 1623 CAC PGY+ + E G G + G C PC +CD G +C N Sbjct: 511 CACPPGYSGLSCETCEPGYYRKHEGKFLGK-CLPCNCNRHAKSCDANTGKCNNCLHNTIG 569 Query: 1624 GKC-HCKENHY--KPEGTA-ECLPCQCYAAGSEN---SSC---EAATGQC-HCRPGVIGR 1672 C CK+ +Y GT +C PC C N S+C + C +C+ G GR Sbjct: 570 KNCEQCKKGYYGDPTVGTEDDCRPCACPMTKPPNKFSSTCFLDKDGKQTCDNCQLGYKGR 629 Query: 1673 ACDACANAYA--EVTPNSGCEVVYD-GC-PRSFAGGVWWPRTK 1711 C++C + + C+ D GC PR A P T+ Sbjct: 630 NCESCLTPFVGNPLVIGDYCKFEEDCGCDPRGSANSSCNPFTR 672 >SB_12645| Best HMM Match : Laminin_EGF (HMM E-Value=3e-31) Length = 541 Score = 40.7 bits (91), Expect = 0.016 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 13/90 (14%) Query: 1596 GGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSE--- 1652 G + GG C C + T G + C + CK+ +++P G + P C A + Sbjct: 440 GRYEGGGVCEDCQHN-TAGIN--CER------CKQGYFRPRGVDKTSPFACRACNCDPQY 490 Query: 1653 -NSSCEAATGQCHCRPGVIGRACDACANAY 1681 C G C C+P G CD C + Sbjct: 491 TTGRCYDENGDCECKPRYGGPRCDRCREGF 520 >SB_6849| Best HMM Match : EGF_2 (HMM E-Value=9.3e-11) Length = 439 Score = 40.7 bits (91), Expect = 0.016 Identities = 41/166 (24%), Positives = 61/166 (36%), Gaps = 20/166 (12%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570 C+ ++C S+ + +C T+ D C CE G C +G C V G Sbjct: 4 CEFISNC--SVPCSHGRCTTAPDK--CECEKYWSGADC--GTYIGTCNNCSSVGGTCSAG 57 Query: 1571 Y-SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629 +CAC PGYT T C ++C G CG +C ++ G C + G + Sbjct: 58 PDTCACRPGYTGPT--C---AVQKCDG-------CGHGSCQISAG-KKSCTCDYGWLNNV 104 Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675 + G C +C + +C CR G CD Sbjct: 105 GDASFTPGRGPCTKIWKCTEPCVYGTCPSDPFKCECRAPYTGTQCD 150 Score = 35.1 bits (77), Expect = 0.82 Identities = 19/75 (25%), Positives = 27/75 (36%), Gaps = 7/75 (9%) Query: 1616 HPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIG---- 1671 H C KC C++ Y C S +C A C CRPG G Sbjct: 16 HGRCTTAPDKCECEK--YWSGADCGTYIGTCNNCSSVGGTCSAGPDTCACRPGYTGPTCA 73 Query: 1672 -RACDACANAYAEVT 1685 + CD C + +++ Sbjct: 74 VQKCDGCGHGSCQIS 88 >SB_58051| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 42 Score = 40.7 bits (91), Expect = 0.016 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 C S+PC NG+ C++ D Y C C G+TG+ C Sbjct: 6 CDSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHC 39 Score = 33.5 bits (73), Expect = 2.5 Identities = 13/30 (43%), Positives = 16/30 (53%), Gaps = 1/30 (3%) Query: 1552 CELGPCG-AARCVPDQTPKGYSCACEPGYT 1580 C+ PC + C Q K Y+C C PGYT Sbjct: 6 CDSSPCSNGSVCNNTQDGKNYTCTCSPGYT 35 >SB_26475| Best HMM Match : Cadherin (HMM E-Value=0.009) Length = 340 Score = 40.7 bits (91), Expect = 0.016 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 10/105 (9%) Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D+N++P + E T Y ENSP GT +G + DP E P+ +S+ G D F++ Sbjct: 19 DVNEAPTLIELSRNTAY--ENSPAGTYVGTLTCEDP-EMPDDSCTFSVV-GPDGVPFAVR 74 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEI 782 SD L+ LD+E+ ++++RA + L+ DV + I Sbjct: 75 ----SDGKSLIVDGPLDHET-NPVLDVIVRATDNGGLYEDVTLTI 114 Score = 33.5 bits (73), Expect = 2.5 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 4/84 (4%) Query: 377 EDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 E+ P GT V TLT D + D+ + + G + F++ S +G+ LI V PLD + Sbjct: 36 ENSPAGTYVGTLTCEDPEMPDDSCTFSVVGPD-GVPFAVRS-DGKSLI-VDGPLDHETNP 92 Query: 436 RYVLTVSATDSGGRSDTAMVQINI 459 + V ATD+GG + + I + Sbjct: 93 VLDVIVRATDNGGLYEDVTLTIGL 116 >SB_5780| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 263 Score = 40.7 bits (91), Expect = 0.016 Identities = 58/221 (26%), Positives = 76/221 (34%), Gaps = 38/221 (17%) Query: 1491 IGTAQSLLNRPTVRENVRDGCQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP-- 1546 IG+ N P N R+ C +C+ C +KC + S CTC G G Sbjct: 15 IGSYHCTCN-PGFSGNGRE-CTDIDECVTGDHTCDKNAKCNNTIGSYHCTCNPGFSGDGR 72 Query: 1547 QC--VSACELGP--CGA-ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGG 1601 C + C G C A+C D T Y C C PG++ C + +EC Sbjct: 73 NCTDIDECVTGDHTCDKNAKC--DNTIGSYHCMCNPGFSGDGRECTDI--DEC------- 121 Query: 1602 SACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPC-QCYAAG---SENSSCE 1657 G CD + CN G HC N C +C +N+ C Sbjct: 122 -VTGDHTCD----KNAKCNNIIGSYHCTCNPGFSGDGRNCTDIDECLTGDHTCDKNAKCN 176 Query: 1658 AATG--QCHCRPGVI--GRAC---DACANAYAEVTPNSGCE 1691 G C C PG GR C D C N+ C+ Sbjct: 177 NTIGSYHCTCNPGFSGDGRNCTDIDECVTGDHTCDKNAKCD 217 Score = 35.5 bits (78), Expect = 0.62 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 13/96 (13%) Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-AR 1561 C +C+ C +KC + S CTC G G C + C G C A+ Sbjct: 156 CTDIDECLTGDHTCDKNAKCNNTIGSYHCTCNPGFSGDGRNCTDIDECVTGDHTCDKNAK 215 Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597 C D T Y C C PG++ C ++ +EC G Sbjct: 216 C--DNTIGSYHCTCNPGFSGNGRECTDT--DECVTG 247 >SB_7527| Best HMM Match : DSL (HMM E-Value=2.5e-34) Length = 542 Score = 40.3 bits (90), Expect = 0.022 Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 20/146 (13%) Query: 1538 TCEAGRVGPQCVSACELGP---C---GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGK 1591 TC G G +C C P C G C+P+ K S C P + +G+ Sbjct: 304 TCLPGWHGDRCNIYCRKTPTSICDGSGKKYCLPNWYGKDCSKYCAPTGNFACNSL--TGE 361 Query: 1592 EECPGGWWGGSACGPCAC--DVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAA 1649 C GW+G C D T + C+ E G+ C + Y GT C+ + Sbjct: 362 RGCVAGWYGDQCDRYCIATHDDTAAFS--CS-ETGEKVCHKGWY---GTN----CERHCV 411 Query: 1650 GSENSSCEAATGQCHCRPGVIGRACD 1675 + NS C TG+ C G G CD Sbjct: 412 RTRNSVCSNITGERICNKGWHGVNCD 437 Score = 34.7 bits (76), Expect = 1.1 Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 23/125 (18%) Query: 1589 SGKEECPGGWWGGSACGPCA-----------CDVTRGYH---PHCNKENGKCHCKENHYK 1634 +G++ C GW G S PC CD T G P + + +C++ Sbjct: 265 TGRKICLPGWHGVSCRVPCVPHNDNVNGHYTCDATTGSKTCLPGWHGDRCNIYCRKTPTS 324 Query: 1635 ---PEGTAECLP------CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685 G CLP C Y A + N +C + TG+ C G G CD A + T Sbjct: 325 ICDGSGKKYCLPNWYGKDCSKYCAPTGNFACNSLTGERGCVAGWYGDQCDRYCIATHDDT 384 Query: 1686 PNSGC 1690 C Sbjct: 385 AAFSC 389 >SB_34550| Best HMM Match : VWA (HMM E-Value=0) Length = 519 Score = 40.3 bits (90), Expect = 0.022 Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 +C++ PC N C+ ++ + C C G GKDC+ Sbjct: 4 KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 37 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC-ADSTGP 1354 C C S+PC C + + ++ C CK+G +C D T P Sbjct: 36 CSLDVDECKSSPCNKNQNCINSFGSFTCVCKDGLKADNCETDFTDP 81 >SB_1891| Best HMM Match : EGF (HMM E-Value=6.5e-15) Length = 106 Score = 40.3 bits (90), Expect = 0.022 Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349 +C++ PC N C+ ++ + C C G GKDC+ Sbjct: 33 KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 66 Score = 33.1 bits (72), Expect = 3.3 Identities = 11/39 (28%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C S+PC C + + ++ C CK+G +C Sbjct: 65 CSLDVDECKSSPCNKNQNCINSFGSFTCVCKDGFKADNC 103 >SB_53569| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 921 Score = 39.9 bits (89), Expect = 0.029 Identities = 47/173 (27%), Positives = 65/173 (37%), Gaps = 31/173 (17%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG----PQC--VSACEL--GPCGAARC 1562 C +CM I P C+ S C C G V C V+ CE+ G CG C Sbjct: 476 CMDIDECMEGI-PECFNCINLRGSYRCECGQGFVPNANQTHCSDVNECEVQNGGCGKHTC 534 Query: 1563 VPDQTPKGYSCACEPGYTL--TTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620 + T Y C C GY L T C++ +EC G C T G Sbjct: 535 I--NTYGSYKCQCLDGYRLDARTEQCVDI--DECARNHGKGDC--EHLCTNTVG------ 582 Query: 1621 KENGKCHCKENHYKPEGTAECL---PCQCYAAGSENSSCEAATG--QCHCRPG 1668 + C C + Y+ +G +C+ C + +C + G +C CRPG Sbjct: 583 --SFSCSCHQG-YRLKGKHQCVDVDECSDNSLNRCQQTCNNSIGSFKCTCRPG 632 Score = 35.1 bits (77), Expect = 0.82 Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 7/99 (7%) Query: 1528 CVTSWDSSTCTCEAG---RVGPQCVSACELGPCGAARCVP--DQTPKGYSCACEPGYTLT 1582 C + S +C+C G + QCV E RC + + + C C PGY L Sbjct: 577 CTNTVGSFSCSCHQGYRLKGKHQCVDVDECSDNSLNRCQQTCNNSIGSFKCTCRPGYHLA 636 Query: 1583 TSGCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCN 1620 G KE+ P G T G+ P H N Sbjct: 637 IDG-FSCTKEKAPPGCGIALEADLANLAATPGWQPAHAN 674 >SB_14925| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 367 Score = 39.9 bits (89), Expect = 0.029 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 10/72 (13%) Query: 1517 CMLSICPPYSKCV--TSWDSSTCTCEAGRVGPQC---VSACELG--PCG-AARCVPDQTP 1568 C S CP + CV + D+ TC C +G G C V C G PC +A C T Sbjct: 63 CSSSPCPVNTTCVPGPTQDTHTCACPSGYTGVDCENDVDECSDGQSPCHVSANC--SNTL 120 Query: 1569 KGYSCACEPGYT 1580 ++C C+ G+T Sbjct: 121 GSFTCTCKDGFT 132 Score = 35.9 bits (79), Expect = 0.47 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 1314 RSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDC 1348 ++ CSS+PC C DT+ C C G+TG DC Sbjct: 60 KNGCSSSPCPVNTTCVPGPTQDTHTCACPSGYTGVDC 96 Score = 35.1 bits (77), Expect = 0.82 Identities = 46/191 (24%), Positives = 72/191 (37%), Gaps = 33/191 (17%) Query: 1550 SACELGPCGA-ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA 1608 + C PC CVP T ++CAC GY T C E+ +EC G S C A Sbjct: 61 NGCSSSPCPVNTTCVPGPTQDTHTCACPSGY--TGVDC-ENDVDECSD---GQSPCHVSA 114 Query: 1609 -CDVTRGYHPHCNKENGKCHCKENHYKPEGTA-----ECL-PCQCYAAGSENSSCEAATG 1661 C T G + C CK+ + +G ECL P C+ N++C G Sbjct: 115 NCSNTLG--------SFTCTCKDG-FTGDGLTCKDVNECLRPNACHV----NATCTNTIG 161 Query: 1662 QCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCP 1721 +C + + ++ + + C+ ++ P S G+++ G + C Sbjct: 162 SYNCSCQTLHH-----GDGHSCLLKGTSCQEIHSRFPHSL-DGMFYIVGNHGYPYLAHCD 215 Query: 1722 PGSSGRATRTC 1732 S G C Sbjct: 216 MTSFGGGWTMC 226 Score = 35.1 bits (77), Expect = 0.82 Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 1310 CPEKRSRCSS--APCYNGAECSDLWDTYICDCKEGHTG 1345 C CS +PC+ A CS+ ++ C CK+G TG Sbjct: 96 CENDVDECSDGQSPCHVSANCSNTLGSFTCTCKDGFTG 133 Score = 33.9 bits (74), Expect = 1.9 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 4/37 (10%) Query: 1043 TCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079 TC CP G+TGV+CE + + S DG S C + C Sbjct: 84 TCACPSGYTGVDCENDVDECS---DGQ-SPCHVSANC 116 >SB_3454| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 123 Score = 39.9 bits (89), Expect = 0.029 Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C +PC N C ++ D+Y C C G GKDC Sbjct: 11 CYPSPCKNAGTCVEVGDSYQCSCHVGWIGKDC 42 Score = 36.3 bits (80), Expect = 0.35 Identities = 14/33 (42%), Positives = 16/33 (48%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353 PC NG CS+ TY C+C G G C G Sbjct: 53 PCQNGGTCSESLGTYRCNCMSGWQGLSCEVGCG 85 Score = 35.5 bits (78), Expect = 0.62 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 8/84 (9%) Query: 1511 CQSRADCM-LSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPK 1569 C + + C+ ++ C C S + C C +G G +CE+G CG+ C P+ Sbjct: 42 CGTESKCLPINPCQNGGTCSESLGTYRCNCMSGWQG----LSCEVG-CGS--CHPNAYCM 94 Query: 1570 GYSCACEPGYTLTTSGCIESGKEE 1593 C C PGY C +G E+ Sbjct: 95 MDKCVCNPGYIGDGITCDVTGHED 118 Score = 33.5 bits (73), Expect = 2.5 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSAC-ELGPC-GAARCVPDQTPKGYS 1572 C S C CV DS C+C G +G C S C + PC C ++ Y Sbjct: 11 CYPSPCKNAGTCVEVGDSYQCSCHVGWIGKDCGTESKCLPINPCQNGGTC--SESLGTYR 68 Query: 1573 CACEPGY 1579 C C G+ Sbjct: 69 CNCMSGW 75 >SB_48850| Best HMM Match : EGF_CA (HMM E-Value=2.1e-27) Length = 83 Score = 39.9 bits (89), Expect = 0.029 Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 7/78 (8%) Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELGPCGAARCVPDQTPK 1569 +C L+I CP CV + S TC C+ G V C + C LG Sbjct: 4 ECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCFNYD 63 Query: 1570 G-YSCACEPGYTLTTSGC 1586 G Y+C C+ GYTL C Sbjct: 64 GSYTCRCKRGYTLVNKTC 81 Score = 32.7 bits (71), Expect = 4.4 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 10/75 (13%) Query: 1549 VSACELG--PCGAAR-CVPDQTPKGYSCACEPGYTLTTSGCIE-----SGKEECPGGWWG 1600 + C+L C A R CV + Y+C C+PGYTL + C + G CP Sbjct: 2 IDECKLNISTCPANRYCVNNDG--SYTCKCKPGYTLVNNTCEDIDECALGVANCPASADC 59 Query: 1601 GSACGPCACDVTRGY 1615 + G C RGY Sbjct: 60 FNYDGSYTCRCKRGY 74 >SB_40335| Best HMM Match : EGF (HMM E-Value=2.5e-09) Length = 309 Score = 39.9 bits (89), Expect = 0.029 Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 1315 SRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348 S C + PC+NGA C D +Y C C G TGK C Sbjct: 151 SACKNNPCHNGATCHQENDESYKCACASGFTGKHC 185 >SB_20425| Best HMM Match : EGF_CA (HMM E-Value=1.2e-20) Length = 144 Score = 39.9 bits (89), Expect = 0.029 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 10/74 (13%) Query: 1037 YPVTSFTCQCPEGFTGVN--CETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSI 1094 Y +C +GF VN CE I E GDG +C+ G+ CV R GG CQ Sbjct: 25 YRCEGVAIRCQQGFEPVNGKCEDIN-----ECTGDGKVCQPGTVCV-NRVGGFTCQPMPC 78 Query: 1095 DAAY--TTAVCELR 1106 + Y VCE + Sbjct: 79 PSGYIRVNGVCECK 92 >SB_15408| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 779 Score = 39.9 bits (89), Expect = 0.029 Identities = 50/183 (27%), Positives = 63/183 (34%), Gaps = 31/183 (16%) Query: 1527 KCVTSWDSSTCTCEAGRVGPQCVSACE--------LGPCGAARCVPDQTPKGYSCACEPG 1578 KCV + S C C AGR + CE C RCV T GY C C G Sbjct: 104 KCVNTVGSFKCDCGAGRTMDPVTNKCEDVDECKTITNICANGRCV--NTNGGYRCECPRG 161 Query: 1579 YTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTR--GYHPHCNKE--NGKCHCKENH 1632 + L+ G CI + W + C + R C K NG CH + Sbjct: 162 FALSQDGMYCIAT---------WALATSLMCLLRMLRKDSTPGRCYKRIVNGYCHMGSSL 212 Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEA-ATGQCHCRPGVIGRA----CDACANAYAEVTPN 1687 + C Q A G + C A T + + GV+ A D C A PN Sbjct: 213 STTQAACCCSMMQSKAWGPDCKRCPAPGTDEYNKLCGVVPSAKPPEVDEC-RMDANACPN 271 Query: 1688 SGC 1690 C Sbjct: 272 GRC 274 Score = 33.1 bits (72), Expect = 3.3 Identities = 22/81 (27%), Positives = 29/81 (35%), Gaps = 11/81 (13%) Query: 1546 PQCVSACEL--GPCGAARCVPDQTPKGYSCACEPGYTLTT---SGCIESGKEECPGGWWG 1600 P V C + C RC+ P G+ C C GY L T + C++ + E Sbjct: 256 PPEVDECRMDANACPNGRCI--DMPSGFRCVCNDGYILPTGRDNKCVDKNECEADSTLCT 313 Query: 1601 GSAC----GPCACDVTRGYHP 1617 C G C GY P Sbjct: 314 NGRCVNTEGSYKCTCNNGYKP 334 >SB_7767| Best HMM Match : Laminin_EGF (HMM E-Value=3.4e-05) Length = 52 Score = 39.9 bits (89), Expect = 0.029 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 6/51 (11%) Query: 1644 CQCYAAGS---ENSSCEAATGQCHCRPGVIGRACDAC-ANAYAEVTPNSGC 1690 C C + ++ C A TGQC C+ + GR CD C NAY T + GC Sbjct: 2 CDCVLPNTLYGNSTVCNATTGQCTCKEKISGRTCDRCHENAYN--TSDRGC 50 >SB_3977| Best HMM Match : EGF (HMM E-Value=1.8e-09) Length = 108 Score = 39.9 bits (89), Expect = 0.029 Identities = 14/37 (37%), Positives = 19/37 (51%) Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 E +C + PC NG C + Y C C EG+ G +C Sbjct: 17 EDIDKCHAMPCMNGGTCIATLNNYRCQCPEGYRGSNC 53 Score = 33.9 bits (74), Expect = 1.9 Identities = 12/23 (52%), Positives = 16/23 (69%) Query: 1036 IYPVTSFTCQCPEGFTGVNCETI 1058 I + ++ CQCPEG+ G NCE I Sbjct: 34 IATLNNYRCQCPEGYRGSNCEGI 56 >SB_3108| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 631 Score = 39.9 bits (89), Expect = 0.029 Identities = 50/187 (26%), Positives = 62/187 (33%), Gaps = 34/187 (18%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574 C +KC S CTC G G C + C G C A+C + T Y C Sbjct: 330 CDKNAKCNNIIGSYHCTCNPGFSGDGRNCTDIDECVTGDHTCDKNAKC--NNTIGSYHCT 387 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634 C PG++ C + +EC G CD + CN G HC N Sbjct: 388 CNPGFSGDGRNCTDI--DEC--------VTGDHTCD----KNAKCNNTIGSYHCMCNPGF 433 Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC---DACANAYAE 1683 EC G +N+ C G C C PG GR C D C Sbjct: 434 SGDGRECTDIDECVTGDHTCDKNAKCNNIIGSYHCTCNPGFSGDGRNCTDIDECVTGDHT 493 Query: 1684 VTPNSGC 1690 N+ C Sbjct: 494 CDKNAKC 500 Score = 38.7 bits (86), Expect = 0.066 Identities = 48/198 (24%), Positives = 64/198 (32%), Gaps = 32/198 (16%) Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGPCGAAR-CV 1563 C +C C +KC + S C C G G +C + C G + + Sbjct: 153 CSETDECSAGNHTCGKNAKCNNTIGSYHCMCNPGFSGDGRECTDIDECVTGDHTCDKNAI 212 Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKEN 1623 + T Y C C PG++ C + +EC A G CD + CN Sbjct: 213 CNNTIGSYHCRCNPGFSGDGRNCTDI--DEC--------ATGDHICD----KNAKCNNTI 258 Query: 1624 GKCHCKENHYKPEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC- 1674 G HC N C G +N+ C G C C PG GR C Sbjct: 259 GSYHCMCNPGFSGDGRNCTDIDECVTGDHTCDKNAKCNNTIGSYHCMCNPGFSGDGRECT 318 Query: 1675 --DACANAYAEVTPNSGC 1690 D C N+ C Sbjct: 319 DIDECVTGDHTCDKNAKC 336 Score = 35.5 bits (78), Expect = 0.62 Identities = 34/108 (31%), Positives = 43/108 (39%), Gaps = 16/108 (14%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574 C +KC + S C C G G C + C G C A+C D T Y C Sbjct: 494 CDKNAKCNNTIGSYHCMCNPGFSGDGRNCTDIDECVTGDHTCDKNAKC--DNTIGSYHCT 551 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDVTRG-YHPHCN 1620 C PG++ C ++ +EC G C A C T G YH CN Sbjct: 552 CNPGFSGNGRECTDT--DECV---TGDHTCDKNARCGNTIGSYHCTCN 594 Score = 31.9 bits (69), Expect = 7.6 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 11/83 (13%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QCVSA--CELGP--CGA-ARCVPDQTPKGYSCA 1574 C +KC + S CTC G G +C C G C ARC T Y C Sbjct: 535 CDKNAKCDNTIGSYHCTCNPGFSGNGRECTDTDECVTGDHTCDKNARC--GNTIGSYHCT 592 Query: 1575 CEPGYTLTTSGCIESGKEECPGG 1597 C PG++ C + +EC G Sbjct: 593 CNPGFSGNGRECTDI--DECVTG 613 >SB_7933| Best HMM Match : GCC2_GCC3 (HMM E-Value=1.4e-18) Length = 1023 Score = 39.5 bits (88), Expect = 0.038 Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 37/232 (15%) Query: 1520 SICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSACELGP----CGAARCVPDQTPKGYS-- 1572 S CP +C +S CT + VG S C+ P C +P P G Sbjct: 270 SACPAGYECSVG-TASLCTAGQYSTVGSP--SGCQTCPSNKVCADPSQLPQNCPAGEEVA 326 Query: 1573 ---CACEPGYTLTTSGCIESGKEECPGGWW---GGSACGPCACDVTRGYHPHCNKENGKC 1626 AC+P S E+ + C G++ G S+C PC+ H N+ Sbjct: 327 ASKAACQPCAAGEYSNTGEAC-QPCTTGYFSLGGASSCTPCSIG-----HQCSNQTIAPV 380 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVI--GRACDACANAYAEV 1684 C Y P G A C C+ AG+ A+ C G G+ +C A Sbjct: 381 RCSPGEYAPAGQANCTACE---AGTYCPDVPLASPYM-CTNGTYSNGQRQTSCQTCQAGY 436 Query: 1685 TPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETK 1736 SG + + G + +K G +T T+CP G S A+++ D K Sbjct: 437 RCGSGAK-----SETACGDGTY---SKEGSDTCTECPAGHS-CASKSADPVK 479 Score = 32.7 bits (71), Expect = 4.4 Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 14/176 (7%) Query: 1526 SKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTT-- 1583 S+CV +C + PQ +A P G C P Q+ K PG T T Sbjct: 787 SRCVECPAGQSCMSGSSPTTPQDCAAGTYSPPGFGTCKPCQSGKKLVNPVNPGATYCTPC 846 Query: 1584 ---SGC--IESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCHCKENHYKPEG 1637 S C S + C G + C D GY P + + +C Sbjct: 847 PAGSSCPTPSSPRVPCTAGTYSLEGVAACV-DCPVGYMCPSTSWQPLRCPFGTTTLGASK 905 Query: 1638 TAECLPCQC-YAAGS-ENSSCEAATGQCHCRPGVIGRAC---DACANAYAEVTPNS 1688 C C YA + EN+ G+ + G C ACA VTP S Sbjct: 906 ALNCTDCPAGYACTTPENNITACNQGEYSLKRGARCITCPAGSACAQTDLHVTPVS 961 >SB_58992| Best HMM Match : VWA (HMM E-Value=2.4e-15) Length = 303 Score = 39.5 bits (88), Expect = 0.038 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 1286 SDFYIDHKFID-LNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHT 1344 S F I K I+ L SYV + G + CSS+PC NG C ++Y C C+ + Sbjct: 139 SQFIIADKNINVLGSYV--DRLRNGIGGVTNPCSSSPCLNGGSCVKTSNSYNCTCRAAYN 196 Query: 1345 GKDC 1348 G C Sbjct: 197 GDRC 200 >SB_43977| Best HMM Match : VWA (HMM E-Value=4.9e-13) Length = 227 Score = 39.5 bits (88), Expect = 0.038 Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S+PC NG CS L Y+C C + G C Sbjct: 5 CASSPCKNGGTCSKLSSGYVCKCTKQFNGSRC 36 >SB_32754| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 5659 Score = 39.5 bits (88), Expect = 0.038 Identities = 53/207 (25%), Positives = 79/207 (38%), Gaps = 35/207 (16%) Query: 1503 VRENVRDG--CQSRADCML--SICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGP-- 1556 +R + DG C +C L + C ++C+ S S +C C+ G G + +LGP Sbjct: 529 LRGYIGDGKTCIDFDECKLPKNDCDVNAECINSIGSYSCICKPGFTG-NGKTCTDLGPVK 587 Query: 1557 ----CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDV 1611 CG D K ++C C+ GY + C K EC G C P A C Sbjct: 588 CDPTCGDLETCVDIKGK-FTCVCKNGYQIVDGEC--KDKNECVG---SDLLCDPNALCTN 641 Query: 1612 TRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSE----NSSCEAATGQ--CHC 1665 T G + C CK ++ +G C + GS N+ C G C C Sbjct: 642 TPGSY--------LCRCKSG-FQGDGKT-CADIDECSDGSHDCHVNAICTNVPGTFLCRC 691 Query: 1666 RPGVIGRACDACANAYAEVTPNSGCEV 1692 G +G CA+ + C++ Sbjct: 692 INGFLGDG-KLCADINECFEGTANCDI 717 Score = 37.1 bits (82), Expect = 0.20 Identities = 47/189 (24%), Positives = 68/189 (35%), Gaps = 39/189 (20%) Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QCVS--ACEL--GPCGA-ARCVPDQTPKGYSCA 1574 C + C + + C C G +G C+ C+L C A C+ + YSC Sbjct: 511 CSVNALCTNTDGTFICRCLRGYIGDGKTCIDFDECKLPKNDCDVNAECI--NSIGSYSCI 568 Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK--CHCKENH 1632 C+PG+T C + GP CD T G C GK C CK + Sbjct: 569 CKPGFTGNGKTCTD---------------LGPVKCDPTCGDLETCVDIKGKFTCVCKNGY 613 Query: 1633 YKPEGTA----ECLPCQCYAAGSENSSCEAATGQ--CHCRPGV--IGRAC---DACANAY 1681 +G EC+ N+ C G C C+ G G+ C D C++ Sbjct: 614 QIVDGECKDKNECVGSDLLC--DPNALCTNTPGSYLCRCKSGFQGDGKTCADIDECSDGS 671 Query: 1682 AEVTPNSGC 1690 + N+ C Sbjct: 672 HDCHVNAIC 680 Score = 35.9 bits (79), Expect = 0.47 Identities = 47/179 (26%), Positives = 70/179 (39%), Gaps = 33/179 (18%) Query: 1507 VRDG--CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQCVSACELGPCGAA 1560 V DG C + +C+ C + C+ S S +C C G G QC E Sbjct: 204 VGDGKTCVDKDECVEEDHDCAKSADCINSVGSYSCQCRPGFEGDGKQCKDVDECASVLHN 263 Query: 1561 RCVPD----QTPKGYSCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCACDV 1611 +C P+ + Y C C+ GYT C + + ++C + G C Sbjct: 264 KCDPNALCTNSVGSYVCRCKKGYTGDGITCKDIDECTNKTDDCDANALCTNVLGSFVCRC 323 Query: 1612 TRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPG 1668 +G+ + NGK C P+ EC P A G+ NS C +AA +C C+ G Sbjct: 324 LKGF-----EGNGKT-C-----IPKLQTECNP----ACGN-NSECKMQAAGAECVCKMG 366 Score = 33.9 bits (74), Expect = 1.9 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 2/26 (7%) Query: 1039 VTSFTCQCPEGFT--GVNCETILTKA 1062 V S+ CQC EG+T G NC+ I+TK+ Sbjct: 725 VGSYNCQCMEGYTGDGKNCQAIITKS 750 >SB_27540| Best HMM Match : Laminin_EGF (HMM E-Value=5.4e-12) Length = 674 Score = 39.5 bits (88), Expect = 0.038 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 14/91 (15%) Query: 1626 CH-CKENHYKPEGTA-----ECLPCQCYAAGSE--NSSC-EAATGQCHCRPGVIGRACDA 1676 CH C+++ ++ G + C PCQC G E +SC ++G C C+ V C Sbjct: 276 CHVCRDDFFREPGKSLSAVDVCSPCQCTGPGVETGKTSCARVSSGNCTCKKYVREPTCGQ 335 Query: 1677 CANAYAEVTPNS--GCEVVYDGC-PRSFAGG 1704 C Y ++ ++ GC+ C P+ GG Sbjct: 336 CMKGYFNLSSSNPEGCQAC--NCNPKGTLGG 364 >SB_7814| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 61 Score = 39.5 bits (88), Expect = 0.038 Identities = 25/58 (43%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSY 223 D PV A + A+D D+GAN + Y+I G F I DS SG +SL L Y Q +Y Sbjct: 5 DTPV-ATVIASDKDIGANRRLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNY 60 >SB_34004| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 235 Score = 39.1 bits (87), Expect = 0.050 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 21/106 (19%) Query: 1001 ICVHEPCLNFE--ECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETI 1058 IC C N + EC+T N + +N++ +TC+C GFTG NCE Sbjct: 116 ICSLRYCGNGDVNECVTKKPCKNGASCINNEG----------GYTCKCTSGFTGKNCEND 165 Query: 1059 LTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 + + + C++G+ C+ +GG C+ C+ + +T CE Sbjct: 166 VNECVTK-----KPCKNGASCI-NNKGGYTCK-CT--SGFTGKNCE 202 Score = 38.3 bits (85), Expect = 0.088 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 1310 CPEKRSRC-SSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C + PC NGA C + Y C C G TGK+C Sbjct: 162 CENDVNECVTKKPCKNGASCINNKGGYTCKCTSGFTGKNC 201 Score = 37.5 bits (83), Expect = 0.15 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 8/89 (8%) Query: 1498 LNRPTVRENVRDGCQSRADCMLSI-CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC- 1552 L RPT+ G +C+ C + C+ + TC C +G G C V+ C Sbjct: 111 LQRPTICSLRYCGNGDVNECVTKKPCKNGASCINNEGGYTCKCTSGFTGKNCENDVNECV 170 Query: 1553 ELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 PC A C+ ++ GY+C C G+T Sbjct: 171 TKKPCKNGASCINNK--GGYTCKCTSGFT 197 Score = 37.1 bits (82), Expect = 0.20 Identities = 14/28 (50%), Positives = 16/28 (57%) Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDC 1348 PC NGA C + Y C C G TGK+C Sbjct: 135 PCKNGASCINNEGGYTCKCTSGFTGKNC 162 >SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40) Length = 1042 Score = 39.1 bits (87), Expect = 0.050 Identities = 36/101 (35%), Positives = 43/101 (42%), Gaps = 15/101 (14%) Query: 1528 CVTSWDSSTCTCEAGRV--GPQCVSACELGPCGAA-RCVPDQTPKG----YSCACEPGYT 1580 CV + S C C AG G QC E CGA+ RC + T Y CAC+PG+T Sbjct: 735 CVNTPGSYACVCPAGYTVSGYQCNDVNE---CGASDRCHVNATCTNTIGSYICACKPGFT 791 Query: 1581 LTTSGCIESGKEECPGGWWGGSACGPCACDVTRG-YHPHCN 1620 C + +EC G S CD T G Y CN Sbjct: 792 GNGFNCTD--VDECTMG--THSCHANAQCDNTIGSYTCRCN 828 Score = 32.3 bits (70), Expect = 5.8 Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGK--DCAD 1350 C + +S C+ A C++ +YIC CK G TG +C D Sbjct: 757 CNDVNECGASDRCHVNATCTNTIGSYICACKPGFTGNGFNCTD 799 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.317 0.134 0.404 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 94,751,511 Number of Sequences: 59808 Number of extensions: 4279957 Number of successful extensions: 19918 Number of sequences better than 10.0: 426 Number of HSP's better than 10.0 without gapping: 242 Number of HSP's successfully gapped in prelim test: 184 Number of HSP's that attempted gapping in prelim test: 10054 Number of HSP's gapped (non-prelim): 5140 length of query: 2796 length of database: 16,821,457 effective HSP length: 95 effective length of query: 2701 effective length of database: 11,139,697 effective search space: 30088321597 effective search space used: 30088321597 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 69 (31.9 bits)
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