SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000467-TA|BGIBMGA000467-PA|IPR002126|Cadherin,
IPR006209|EGF-like, IPR012680|Laminin G, subdomain 2,
IPR002049|EGF-like, laminin, IPR001879|Hormone receptor,
extracellular, IPR000203|GPS, IPR000152|Aspartic acid and asparagine
hydroxylation site, IPR013032|EGF-like region,
IPR000005|Helix-turn-helix, AraC type, IPR000083|Fibronectin, type I,
IPR006210|EGF, IPR001791|Laminin G, IPR001881|EGF-like
calcium-binding, IPR000742|EGF-like, type 3
         (2796 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_18656| Best HMM Match : No HMM Matches (HMM E-Value=.)             614   e-175
SB_22798| Best HMM Match : Cadherin (HMM E-Value=0)                   434   e-121
SB_58036| Best HMM Match : Cadherin (HMM E-Value=0)                   386   e-106
SB_38622| Best HMM Match : No HMM Matches (HMM E-Value=.)             385   e-106
SB_25361| Best HMM Match : Cadherin (HMM E-Value=0)                   384   e-106
SB_34906| Best HMM Match : Cadherin (HMM E-Value=0)                   368   e-101
SB_46477| Best HMM Match : No HMM Matches (HMM E-Value=.)             351   4e-96
SB_48962| Best HMM Match : Cadherin (HMM E-Value=0)                   345   3e-94
SB_45916| Best HMM Match : Cadherin (HMM E-Value=0)                   341   5e-93
SB_5763| Best HMM Match : Cadherin (HMM E-Value=0)                    332   2e-90
SB_47886| Best HMM Match : Cadherin (HMM E-Value=0)                   329   2e-89
SB_51779| Best HMM Match : No HMM Matches (HMM E-Value=.)             304   7e-82
SB_1988| Best HMM Match : No HMM Matches (HMM E-Value=.)              288   5e-77
SB_15712| Best HMM Match : Cadherin (HMM E-Value=0)                   277   7e-74
SB_36047| Best HMM Match : No HMM Matches (HMM E-Value=.)             274   5e-73
SB_9756| Best HMM Match : Cadherin (HMM E-Value=0)                    268   4e-71
SB_41246| Best HMM Match : Cadherin (HMM E-Value=0)                   266   2e-70
SB_55456| Best HMM Match : Cadherin (HMM E-Value=0)                   242   3e-63
SB_18678| Best HMM Match : No HMM Matches (HMM E-Value=.)             240   1e-62
SB_22450| Best HMM Match : No HMM Matches (HMM E-Value=.)             238   4e-62
SB_9507| Best HMM Match : Cadherin (HMM E-Value=0)                    238   4e-62
SB_28228| Best HMM Match : Cadherin (HMM E-Value=0)                   227   1e-58
SB_27857| Best HMM Match : Cadherin (HMM E-Value=0)                   221   9e-57
SB_56770| Best HMM Match : Cadherin (HMM E-Value=0)                   216   2e-55
SB_35949| Best HMM Match : Cadherin (HMM E-Value=0)                   214   1e-54
SB_50345| Best HMM Match : Cadherin (HMM E-Value=0)                   202   4e-51
SB_56686| Best HMM Match : Cadherin (HMM E-Value=0)                   199   2e-50
SB_40275| Best HMM Match : Cadherin (HMM E-Value=0)                   196   2e-49
SB_35963| Best HMM Match : Cadherin (HMM E-Value=0)                   191   6e-48
SB_7364| Best HMM Match : Cadherin (HMM E-Value=0)                    182   4e-45
SB_18765| Best HMM Match : Cadherin (HMM E-Value=0)                   175   6e-43
SB_44524| Best HMM Match : Cadherin (HMM E-Value=0)                   173   1e-42
SB_33995| Best HMM Match : Cadherin (HMM E-Value=3e-39)               165   5e-40
SB_39408| Best HMM Match : Cadherin (HMM E-Value=0)                   165   6e-40
SB_34907| Best HMM Match : Cadherin (HMM E-Value=0)                   162   4e-39
SB_51258| Best HMM Match : Cadherin (HMM E-Value=0)                   153   2e-36
SB_24627| Best HMM Match : Cadherin (HMM E-Value=0)                   145   4e-34
SB_14427| Best HMM Match : Cadherin (HMM E-Value=0)                   144   7e-34
SB_56813| Best HMM Match : Cadherin (HMM E-Value=5.8e-40)             137   1e-31
SB_30491| Best HMM Match : No HMM Matches (HMM E-Value=.)             136   2e-31
SB_28202| Best HMM Match : Cadherin (HMM E-Value=1.8e-29)             133   2e-30
SB_4130| Best HMM Match : Cadherin (HMM E-Value=9.3e-29)              124   1e-27
SB_10746| Best HMM Match : Cadherin (HMM E-Value=0)                   119   4e-26
SB_4448| Best HMM Match : No HMM Matches (HMM E-Value=.)              117   2e-25
SB_34938| Best HMM Match : Cadherin (HMM E-Value=1e-25)               109   2e-23
SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0)                106   2e-22
SB_40244| Best HMM Match : Cadherin (HMM E-Value=0)                   105   4e-22
SB_16935| Best HMM Match : Cadherin (HMM E-Value=0)                   102   5e-21
SB_21336| Best HMM Match : No HMM Matches (HMM E-Value=.)             101   6e-21
SB_36411| Best HMM Match : No HMM Matches (HMM E-Value=.)              97   2e-19
SB_15158| Best HMM Match : Cadherin (HMM E-Value=7.5e-23)              96   3e-19
SB_57964| Best HMM Match : No HMM Matches (HMM E-Value=.)              96   4e-19
SB_32317| Best HMM Match : Cadherin (HMM E-Value=1.5e-28)              86   3e-16
SB_56860| Best HMM Match : Cadherin (HMM E-Value=4.4e-16)              82   7e-15
SB_10800| Best HMM Match : No HMM Matches (HMM E-Value=.)              76   4e-13
SB_45116| Best HMM Match : EGF (HMM E-Value=0)                         75   1e-12
SB_54100| Best HMM Match : No HMM Matches (HMM E-Value=.)              74   1e-12
SB_4874| Best HMM Match : No HMM Matches (HMM E-Value=.)               73   3e-12
SB_23044| Best HMM Match : No HMM Matches (HMM E-Value=.)              71   1e-11
SB_16968| Best HMM Match : Laminin_EGF (HMM E-Value=0)                 71   1e-11
SB_35857| Best HMM Match : No HMM Matches (HMM E-Value=.)              71   2e-11
SB_35310| Best HMM Match : Cadherin (HMM E-Value=5.9e-23)              71   2e-11
SB_35194| Best HMM Match : EGF_2 (HMM E-Value=0)                       70   2e-11
SB_6200| Best HMM Match : Laminin_EGF (HMM E-Value=0)                  70   2e-11
SB_10656| Best HMM Match : No HMM Matches (HMM E-Value=.)              68   9e-11
SB_30436| Best HMM Match : No HMM Matches (HMM E-Value=.)              68   9e-11
SB_7853| Best HMM Match : Cadherin (HMM E-Value=9.9)                   68   1e-10
SB_32515| Best HMM Match : FAINT (HMM E-Value=4.5)                     67   2e-10
SB_29802| Best HMM Match : Laminin_EGF (HMM E-Value=0)                 66   5e-10
SB_8046| Best HMM Match : No HMM Matches (HMM E-Value=.)               65   9e-10
SB_25851| Best HMM Match : Laminin_G_2 (HMM E-Value=0)                 64   2e-09
SB_552| Best HMM Match : Laminin_EGF (HMM E-Value=1.3e-23)             64   2e-09
SB_49286| Best HMM Match : Laminin_N (HMM E-Value=0)                   63   3e-09
SB_22952| Best HMM Match : EGF_2 (HMM E-Value=2e-23)                   63   3e-09
SB_42841| Best HMM Match : No HMM Matches (HMM E-Value=.)              63   3e-09
SB_52794| Best HMM Match : No HMM Matches (HMM E-Value=.)              62   6e-09
SB_56285| Best HMM Match : No HMM Matches (HMM E-Value=.)              62   8e-09
SB_50568| Best HMM Match : EGF (HMM E-Value=0)                         62   8e-09
SB_9550| Best HMM Match : GPS (HMM E-Value=1.6e-11)                    61   1e-08
SB_52147| Best HMM Match : EGF (HMM E-Value=0)                         61   1e-08
SB_32355| Best HMM Match : Laminin_EGF (HMM E-Value=0)                 61   1e-08
SB_10244| Best HMM Match : Laminin_EGF (HMM E-Value=0)                 61   1e-08
SB_33333| Best HMM Match : No HMM Matches (HMM E-Value=.)              60   2e-08
SB_31541| Best HMM Match : EGF (HMM E-Value=0)                         60   2e-08
SB_25612| Best HMM Match : Cadherin (HMM E-Value=0.034)                60   3e-08
SB_31961| Best HMM Match : EGF (HMM E-Value=0)                         59   6e-08
SB_32940| Best HMM Match : EGF (HMM E-Value=0)                         59   6e-08
SB_58558| Best HMM Match : EGF (HMM E-Value=0)                         58   1e-07
SB_20112| Best HMM Match : EGF (HMM E-Value=0)                         58   1e-07
SB_18364| Best HMM Match : Cadherin (HMM E-Value=3e-12)                57   2e-07
SB_12265| Best HMM Match : Cadherin (HMM E-Value=1.3e-10)              57   2e-07
SB_49765| Best HMM Match : EGF (HMM E-Value=0)                         56   3e-07
SB_40116| Best HMM Match : EGF (HMM E-Value=0)                         56   3e-07
SB_471| Best HMM Match : Laminin_EGF (HMM E-Value=0)                   56   3e-07
SB_43550| Best HMM Match : Laminin_EGF (HMM E-Value=0)                 56   4e-07
SB_9705| Best HMM Match : Cadherin (HMM E-Value=0.013)                 55   7e-07
SB_32282| Best HMM Match : Laminin_G_2 (HMM E-Value=0)                 55   9e-07
SB_22642| Best HMM Match : No HMM Matches (HMM E-Value=.)              54   1e-06
SB_2045| Best HMM Match : EGF (HMM E-Value=0)                          54   2e-06
SB_8580| Best HMM Match : No HMM Matches (HMM E-Value=.)               54   2e-06
SB_54839| Best HMM Match : No HMM Matches (HMM E-Value=.)              54   2e-06
SB_16910| Best HMM Match : EGF (HMM E-Value=0)                         53   3e-06
SB_3456| Best HMM Match : No HMM Matches (HMM E-Value=.)               53   3e-06
SB_20264| Best HMM Match : No HMM Matches (HMM E-Value=.)              53   4e-06
SB_2152| Best HMM Match : EGF (HMM E-Value=0)                          53   4e-06
SB_13309| Best HMM Match : EGF (HMM E-Value=0)                         52   7e-06
SB_16967| Best HMM Match : Laminin_EGF (HMM E-Value=0)                 52   7e-06
SB_8425| Best HMM Match : EGF (HMM E-Value=0)                          52   7e-06
SB_59261| Best HMM Match : No HMM Matches (HMM E-Value=.)              52   9e-06
SB_28495| Best HMM Match : No HMM Matches (HMM E-Value=.)              51   1e-05
SB_786| Best HMM Match : EGF (HMM E-Value=0)                           51   1e-05
SB_57511| Best HMM Match : EGF_CA (HMM E-Value=0)                      51   1e-05
SB_45521| Best HMM Match : F5_F8_type_C (HMM E-Value=8.6e-23)          50   2e-05
SB_18560| Best HMM Match : No HMM Matches (HMM E-Value=.)              50   2e-05
SB_34444| Best HMM Match : Cadherin (HMM E-Value=0.0043)               50   2e-05
SB_26697| Best HMM Match : EGF (HMM E-Value=7.5e-34)                   50   2e-05
SB_4999| Best HMM Match : EGF_CA (HMM E-Value=0)                       50   2e-05
SB_46333| Best HMM Match : EGF (HMM E-Value=1.10001e-40)               50   3e-05
SB_49700| Best HMM Match : No HMM Matches (HMM E-Value=.)              50   3e-05
SB_37565| Best HMM Match : No HMM Matches (HMM E-Value=.)              50   3e-05
SB_34555| Best HMM Match : EGF (HMM E-Value=7.00649e-45)               50   3e-05
SB_6077| Best HMM Match : EGF (HMM E-Value=0)                          50   3e-05
SB_40912| Best HMM Match : No HMM Matches (HMM E-Value=.)              50   4e-05
SB_50709| Best HMM Match : No HMM Matches (HMM E-Value=.)              49   5e-05
SB_22953| Best HMM Match : EGF_2 (HMM E-Value=1.3e-14)                 49   5e-05
SB_3431| Best HMM Match : EGF (HMM E-Value=1.8e-08)                    49   5e-05
SB_12832| Best HMM Match : No HMM Matches (HMM E-Value=.)              49   6e-05
SB_40516| Best HMM Match : Cadherin (HMM E-Value=0.042)                48   8e-05
SB_23966| Best HMM Match : EGF (HMM E-Value=2.4e-40)                   48   8e-05
SB_16748| Best HMM Match : No HMM Matches (HMM E-Value=.)              48   8e-05
SB_3457| Best HMM Match : No HMM Matches (HMM E-Value=.)               48   8e-05
SB_52148| Best HMM Match : EGF (HMM E-Value=0)                         48   1e-04
SB_48268| Best HMM Match : No HMM Matches (HMM E-Value=.)              48   1e-04
SB_42006| Best HMM Match : EGF_2 (HMM E-Value=8.7e-05)                 48   1e-04
SB_21404| Best HMM Match : VWA (HMM E-Value=8.1e-27)                   48   1e-04
SB_41690| Best HMM Match : DSL (HMM E-Value=0)                         48   1e-04
SB_35429| Best HMM Match : Laminin_EGF (HMM E-Value=5.3e-17)           48   1e-04
SB_1249| Best HMM Match : Cadherin (HMM E-Value=0.0083)                48   1e-04
SB_9975| Best HMM Match : 7tm_2 (HMM E-Value=1.9e-38)                  48   1e-04
SB_46889| Best HMM Match : No HMM Matches (HMM E-Value=.)              47   2e-04
SB_11569| Best HMM Match : No HMM Matches (HMM E-Value=.)              47   2e-04
SB_26778| Best HMM Match : No HMM Matches (HMM E-Value=.)              47   2e-04
SB_47530| Best HMM Match : No HMM Matches (HMM E-Value=.)              47   3e-04
SB_44915| Best HMM Match : VWA (HMM E-Value=0)                         47   3e-04
SB_32721| Best HMM Match : No HMM Matches (HMM E-Value=.)              47   3e-04
SB_29838| Best HMM Match : EGF (HMM E-Value=1.2e-15)                   47   3e-04
SB_13163| Best HMM Match : VWA (HMM E-Value=2.3e-32)                   47   3e-04
SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0)                      47   3e-04
SB_5993| Best HMM Match : EGF_2 (HMM E-Value=9e-14)                    47   3e-04
SB_4760| Best HMM Match : EGF (HMM E-Value=8.29989e-42)                47   3e-04
SB_46360| Best HMM Match : EGF (HMM E-Value=0)                         47   3e-04
SB_44887| Best HMM Match : EGF (HMM E-Value=4.1e-09)                   47   3e-04
SB_26480| Best HMM Match : EGF (HMM E-Value=0)                         47   3e-04
SB_33722| Best HMM Match : EGF_CA (HMM E-Value=0)                      46   3e-04
SB_22957| Best HMM Match : EGF (HMM E-Value=7e-39)                     46   3e-04
SB_40913| Best HMM Match : No HMM Matches (HMM E-Value=.)              46   3e-04
SB_48384| Best HMM Match : No HMM Matches (HMM E-Value=.)              46   4e-04
SB_36058| Best HMM Match : VWA (HMM E-Value=7.4e-23)                   46   6e-04
SB_28093| Best HMM Match : VWA (HMM E-Value=4.4e-33)                   46   6e-04
SB_54456| Best HMM Match : EGF (HMM E-Value=2.3e-31)                   46   6e-04
SB_39378| Best HMM Match : VWA (HMM E-Value=0)                         46   6e-04
SB_5376| Best HMM Match : EGF_CA (HMM E-Value=0)                       46   6e-04
SB_30234| Best HMM Match : No HMM Matches (HMM E-Value=.)              45   8e-04
SB_15312| Best HMM Match : EGF (HMM E-Value=7.1e-21)                   45   8e-04
SB_53619| Best HMM Match : GPS (HMM E-Value=2.4e-15)                   45   8e-04
SB_40564| Best HMM Match : Laminin_EGF (HMM E-Value=3.5e-12)           45   8e-04
SB_52271| Best HMM Match : No HMM Matches (HMM E-Value=.)              45   0.001
SB_16119| Best HMM Match : EGF (HMM E-Value=2e-20)                     45   0.001
SB_52861| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.001
SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.001
SB_26578| Best HMM Match : EGF (HMM E-Value=2.2e-35)                   44   0.001
SB_26267| Best HMM Match : TSP_C (HMM E-Value=0)                       44   0.001
SB_26085| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.001
SB_54230| Best HMM Match : EGF (HMM E-Value=0)                         44   0.001
SB_33876| Best HMM Match : EGF (HMM E-Value=2.4e-08)                   44   0.001
SB_3578| Best HMM Match : No HMM Matches (HMM E-Value=.)               44   0.001
SB_58129| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.002
SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.002
SB_48589| Best HMM Match : EGF (HMM E-Value=2e-19)                     44   0.002
SB_32722| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.002
SB_12742| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.002
SB_11540| Best HMM Match : EGF (HMM E-Value=1.5e-25)                   44   0.002
SB_45954| Best HMM Match : VWA (HMM E-Value=4e-26)                     44   0.002
SB_5527| Best HMM Match : EGF_CA (HMM E-Value=1e-26)                   44   0.002
SB_33579| Best HMM Match : Laminin_G_2 (HMM E-Value=3.2e-34)           44   0.002
SB_30923| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.002
SB_27599| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.002
SB_42661| Best HMM Match : No HMM Matches (HMM E-Value=.)              43   0.003
SB_14079| Best HMM Match : No HMM Matches (HMM E-Value=.)              43   0.003
SB_7343| Best HMM Match : EGF (HMM E-Value=0)                          43   0.003
SB_5020| Best HMM Match : No HMM Matches (HMM E-Value=.)               43   0.003
SB_37317| Best HMM Match : EGF_CA (HMM E-Value=6.6e-25)                43   0.004
SB_28272| Best HMM Match : EGF (HMM E-Value=2.6e-15)                   43   0.004
SB_20457| Best HMM Match : fn3 (HMM E-Value=5.1e-12)                   43   0.004
SB_37171| Best HMM Match : EGF (HMM E-Value=2.6e-15)                   43   0.004
SB_31622| Best HMM Match : EGF (HMM E-Value=4.2e-09)                   43   0.004
SB_19665| Best HMM Match : No HMM Matches (HMM E-Value=.)              43   0.004
SB_32719| Best HMM Match : No HMM Matches (HMM E-Value=.)              42   0.005
SB_26949| Best HMM Match : No HMM Matches (HMM E-Value=.)              42   0.005
SB_23501| Best HMM Match : No HMM Matches (HMM E-Value=.)              42   0.005
SB_21594| Best HMM Match : No HMM Matches (HMM E-Value=.)              42   0.005
SB_33543| Best HMM Match : No HMM Matches (HMM E-Value=.)              42   0.005
SB_32196| Best HMM Match : No HMM Matches (HMM E-Value=.)              42   0.005
SB_44376| Best HMM Match : EGF_CA (HMM E-Value=7.8e-22)                42   0.007
SB_34553| Best HMM Match : F5_F8_type_C (HMM E-Value=8.3e-22)          42   0.007
SB_33149| Best HMM Match : DSL (HMM E-Value=5.60519e-45)               42   0.007
SB_50993| Best HMM Match : EGF (HMM E-Value=3.4e-19)                   42   0.009
SB_47717| Best HMM Match : EGF (HMM E-Value=1.9e-29)                   42   0.009
SB_52863| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.012
SB_47423| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.012
SB_47176| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.012
SB_41795| Best HMM Match : EGF (HMM E-Value=8.7e-11)                   41   0.012
SB_32588| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.012
SB_14770| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.012
SB_7289| Best HMM Match : EGF_CA (HMM E-Value=0)                       41   0.012
SB_4732| Best HMM Match : EGF (HMM E-Value=2.4e-10)                    41   0.012
SB_57080| Best HMM Match : EGF_CA (HMM E-Value=1.4013e-43)             41   0.012
SB_41915| Best HMM Match : F5_F8_type_C (HMM E-Value=9.1e-13)          41   0.012
SB_15410| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.012
SB_48923| Best HMM Match : EGF_CA (HMM E-Value=3.2e-27)                41   0.016
SB_41903| Best HMM Match : HRM (HMM E-Value=0.00061)                   41   0.016
SB_39963| Best HMM Match : EGF (HMM E-Value=1.4e-13)                   41   0.016
SB_39510| Best HMM Match : VWA (HMM E-Value=0)                         41   0.016
SB_33920| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.016
SB_12645| Best HMM Match : Laminin_EGF (HMM E-Value=3e-31)             41   0.016
SB_6849| Best HMM Match : EGF_2 (HMM E-Value=9.3e-11)                  41   0.016
SB_58051| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.016
SB_26475| Best HMM Match : Cadherin (HMM E-Value=0.009)                41   0.016
SB_5780| Best HMM Match : EGF_CA (HMM E-Value=0)                       41   0.016
SB_7527| Best HMM Match : DSL (HMM E-Value=2.5e-34)                    40   0.022
SB_34550| Best HMM Match : VWA (HMM E-Value=0)                         40   0.022
SB_1891| Best HMM Match : EGF (HMM E-Value=6.5e-15)                    40   0.022
SB_53569| Best HMM Match : EGF_CA (HMM E-Value=0)                      40   0.029
SB_14925| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.029
SB_3454| Best HMM Match : No HMM Matches (HMM E-Value=.)               40   0.029
SB_48850| Best HMM Match : EGF_CA (HMM E-Value=2.1e-27)                40   0.029
SB_40335| Best HMM Match : EGF (HMM E-Value=2.5e-09)                   40   0.029
SB_20425| Best HMM Match : EGF_CA (HMM E-Value=1.2e-20)                40   0.029
SB_15408| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.029
SB_7767| Best HMM Match : Laminin_EGF (HMM E-Value=3.4e-05)            40   0.029
SB_3977| Best HMM Match : EGF (HMM E-Value=1.8e-09)                    40   0.029
SB_3108| Best HMM Match : No HMM Matches (HMM E-Value=.)               40   0.029
SB_7933| Best HMM Match : GCC2_GCC3 (HMM E-Value=1.4e-18)              40   0.038
SB_58992| Best HMM Match : VWA (HMM E-Value=2.4e-15)                   40   0.038
SB_43977| Best HMM Match : VWA (HMM E-Value=4.9e-13)                   40   0.038
SB_32754| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.038
SB_27540| Best HMM Match : Laminin_EGF (HMM E-Value=5.4e-12)           40   0.038
SB_7814| Best HMM Match : No HMM Matches (HMM E-Value=.)               40   0.038
SB_34004| Best HMM Match : No HMM Matches (HMM E-Value=.)              39   0.050
SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40)                39   0.050
SB_18916| Best HMM Match : GPS (HMM E-Value=1e-17)                     39   0.050
SB_51485| Best HMM Match : Laminin_EGF (HMM E-Value=0.0035)            39   0.050
SB_32431| Best HMM Match : No HMM Matches (HMM E-Value=.)              39   0.050
SB_32430| Best HMM Match : No HMM Matches (HMM E-Value=.)              39   0.050
SB_26028| Best HMM Match : EGF (HMM E-Value=0.00014)                   39   0.050
SB_15843| Best HMM Match : VWA (HMM E-Value=4.1e-35)                   39   0.050
SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0)                      39   0.066
SB_27751| Best HMM Match : Laminin_G_2 (HMM E-Value=1e-06)             39   0.066
SB_59742| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.088
SB_52403| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.088
SB_42659| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.088
SB_41113| Best HMM Match : VWA (HMM E-Value=1.8e-21)                   38   0.088
SB_35900| Best HMM Match : EGF_CA (HMM E-Value=2.5e-38)                38   0.088
SB_20528| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.088
SB_54457| Best HMM Match : EGF (HMM E-Value=4.6e-31)                   38   0.088
SB_39083| Best HMM Match : PhaC_N (HMM E-Value=0.7)                    38   0.088
SB_15637| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.088
SB_8084| Best HMM Match : EGF_CA (HMM E-Value=2.8026e-45)              38   0.088
SB_56752| Best HMM Match : EGF (HMM E-Value=8.3e-10)                   38   0.12 
SB_47667| Best HMM Match : Ldl_recept_a (HMM E-Value=0)                38   0.12 
SB_36893| Best HMM Match : Fibrinogen_C (HMM E-Value=2.4e-24)          38   0.12 
SB_32444| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.12 
SB_11375| Best HMM Match : EGF_CA (HMM E-Value=0)                      38   0.12 
SB_45136| Best HMM Match : EGF_CA (HMM E-Value=8.7e-36)                38   0.12 
SB_9474| Best HMM Match : EGF (HMM E-Value=2e-08)                      38   0.12 
SB_5962| Best HMM Match : EGF (HMM E-Value=8.5e-09)                    38   0.12 
SB_51974| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.15 
SB_50111| Best HMM Match : GCC2_GCC3 (HMM E-Value=0)                   38   0.15 
SB_18624| Best HMM Match : EGF (HMM E-Value=7.8e-06)                   38   0.15 
SB_42888| Best HMM Match : EGF (HMM E-Value=8.4e-20)                   38   0.15 
SB_22619| Best HMM Match : TSP_1 (HMM E-Value=8.5e-14)                 37   0.20 
SB_45836| Best HMM Match : EGF (HMM E-Value=6.7e-21)                   37   0.20 
SB_38753| Best HMM Match : No HMM Matches (HMM E-Value=.)              37   0.20 
SB_12543| Best HMM Match : TSP_1 (HMM E-Value=1.4e-07)                 37   0.20 
SB_56964| Best HMM Match : Zona_pellucida (HMM E-Value=0)              37   0.27 
SB_49295| Best HMM Match : No HMM Matches (HMM E-Value=.)              37   0.27 
SB_43576| Best HMM Match : EGF_CA (HMM E-Value=2.7e-38)                37   0.27 
SB_30653| Best HMM Match : Cadherin (HMM E-Value=0.0018)               37   0.27 
SB_51462| Best HMM Match : Ion_trans_2 (HMM E-Value=2.3e-15)           37   0.27 
SB_41271| Best HMM Match : EGF (HMM E-Value=1.2e-20)                   37   0.27 
SB_28917| Best HMM Match : No HMM Matches (HMM E-Value=.)              37   0.27 
SB_24004| Best HMM Match : EGF (HMM E-Value=5.7e-14)                   37   0.27 
SB_14763| Best HMM Match : Zona_pellucida (HMM E-Value=0)              37   0.27 
SB_42084| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.35 
SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.35 
SB_12997| Best HMM Match : DSL (HMM E-Value=1.4013e-45)                36   0.35 
SB_11257| Best HMM Match : GCC2_GCC3 (HMM E-Value=2.7e-11)             36   0.35 
SB_50906| Best HMM Match : EGF (HMM E-Value=3.5e-08)                   36   0.35 
SB_10156| Best HMM Match : DSL (HMM E-Value=3.3e-35)                   36   0.35 
SB_825| Best HMM Match : EGF (HMM E-Value=5.6e-08)                     36   0.35 
SB_37500| Best HMM Match : RRM_1 (HMM E-Value=7.3e-38)                 36   0.47 
SB_21661| Best HMM Match : EGF_CA (HMM E-Value=0)                      36   0.47 
SB_14859| Best HMM Match : SEA (HMM E-Value=0.01)                      36   0.47 
SB_673| Best HMM Match : VWA (HMM E-Value=8.9e-25)                     36   0.47 
SB_58882| Best HMM Match : EGF_CA (HMM E-Value=0)                      36   0.47 
SB_33318| Best HMM Match : EGF (HMM E-Value=7.5e-05)                   36   0.47 
SB_50933| Best HMM Match : Laminin_EGF (HMM E-Value=0.0069)            36   0.62 
SB_17565| Best HMM Match : EGF (HMM E-Value=5.1e-05)                   36   0.62 
SB_2182| Best HMM Match : EGF_CA (HMM E-Value=0)                       36   0.62 
SB_38887| Best HMM Match : EGF_CA (HMM E-Value=6.2e-31)                36   0.62 
SB_28027| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.62 
SB_57938| Best HMM Match : Cadherin (HMM E-Value=0.0027)               35   0.82 
SB_42767| Best HMM Match : Thyroglobulin_1 (HMM E-Value=0)             35   0.82 
SB_45647| Best HMM Match : HSP70 (HMM E-Value=0)                       35   0.82 
SB_45586| Best HMM Match : EGF_2 (HMM E-Value=0.00035)                 35   0.82 
SB_41869| Best HMM Match : Laminin_EGF (HMM E-Value=9.7e-23)           35   0.82 
SB_37188| Best HMM Match : Cadherin (HMM E-Value=0.0029)               35   0.82 
SB_36925| Best HMM Match : EGF (HMM E-Value=1.5e-16)                   35   0.82 
SB_7361| Best HMM Match : No HMM Matches (HMM E-Value=.)               35   0.82 
SB_58994| Best HMM Match : EGF_CA (HMM E-Value=2.3e-29)                35   1.1  
SB_50721| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.1  
SB_21681| Best HMM Match : EGF (HMM E-Value=3e-06)                     35   1.1  
SB_19005| Best HMM Match : EGF (HMM E-Value=1.4e-20)                   35   1.1  
SB_55591| Best HMM Match : TIL (HMM E-Value=4.2e-09)                   35   1.1  
SB_47132| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.1  
SB_39056| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.1  
SB_22868| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.1  
SB_22565| Best HMM Match : EGF (HMM E-Value=0.2)                       35   1.1  
SB_10084| Best HMM Match : Cadherin (HMM E-Value=2.4e-06)              35   1.1  
SB_43077| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   1.4  
SB_42051| Best HMM Match : EGF_CA (HMM E-Value=6.9e-35)                34   1.4  
SB_34212| Best HMM Match : EGF (HMM E-Value=1.1e-05)                   34   1.4  
SB_29518| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   1.4  
SB_24277| Best HMM Match : EGF (HMM E-Value=2.4e-06)                   34   1.4  
SB_14044| Best HMM Match : EGF_CA (HMM E-Value=4.1e-13)                34   1.4  
SB_14014| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   1.4  
SB_10438| Best HMM Match : Cadherin (HMM E-Value=0.0027)               34   1.4  
SB_9772| Best HMM Match : EGF_CA (HMM E-Value=3.9e-25)                 34   1.4  
SB_9711| Best HMM Match : EGF (HMM E-Value=2.4e-08)                    34   1.4  
SB_4259| Best HMM Match : No HMM Matches (HMM E-Value=.)               34   1.4  
SB_23241| Best HMM Match : EGF_CA (HMM E-Value=6.3e-30)                34   1.4  
SB_58993| Best HMM Match : EGF_CA (HMM E-Value=0)                      34   1.9  
SB_58780| Best HMM Match : VWA (HMM E-Value=1.3e-34)                   34   1.9  
SB_52309| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   1.9  
SB_51002| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   1.9  
SB_43565| Best HMM Match : EGF (HMM E-Value=2.8e-05)                   34   1.9  
SB_41134| Best HMM Match : EGF_CA (HMM E-Value=0)                      34   1.9  
SB_35287| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   1.9  
SB_13146| Best HMM Match : Laminin_G_2 (HMM E-Value=1.5e-25)           34   1.9  
SB_2428| Best HMM Match : ShTK (HMM E-Value=4.2e-21)                   34   1.9  
SB_55657| Best HMM Match : EGF_CA (HMM E-Value=0)                      34   1.9  
SB_43823| Best HMM Match : MAM (HMM E-Value=0)                         34   1.9  
SB_31249| Best HMM Match : PKD (HMM E-Value=4.9)                       34   1.9  
SB_17530| Best HMM Match : EGF_CA (HMM E-Value=0)                      34   1.9  
SB_16469| Best HMM Match : EGF (HMM E-Value=4e-09)                     34   1.9  
SB_6531| Best HMM Match : EGF_2 (HMM E-Value=0.0016)                   34   1.9  
SB_56885| Best HMM Match : EGF_CA (HMM E-Value=1.1e-08)                33   2.5  
SB_46203| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   2.5  
SB_45060| Best HMM Match : DSL (HMM E-Value=3e-07)                     33   2.5  
SB_36177| Best HMM Match : Integrin_beta (HMM E-Value=0)               33   2.5  
SB_32816| Best HMM Match : EGF_CA (HMM E-Value=3.1e-11)                33   2.5  
SB_53888| Best HMM Match : TSP_3 (HMM E-Value=9.2e-11)                 33   2.5  
SB_41898| Best HMM Match : EGF_CA (HMM E-Value=3.9e-14)                33   2.5  
SB_33267| Best HMM Match : F5_F8_type_C (HMM E-Value=3.4e-10)          33   2.5  
SB_19371| Best HMM Match : C_tripleX (HMM E-Value=0.041)               33   2.5  
SB_18417| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   2.5  
SB_17302| Best HMM Match : Pentaxin (HMM E-Value=1e-09)                33   2.5  
SB_1865| Best HMM Match : DUF1168 (HMM E-Value=5)                      33   2.5  
SB_45154| Best HMM Match : EGF_CA (HMM E-Value=2.8026e-45)             33   3.3  
SB_8644| Best HMM Match : 7tm_1 (HMM E-Value=0)                        33   3.3  
SB_8305| Best HMM Match : Plasmodium_HRP (HMM E-Value=8.8)             33   3.3  
SB_5768| Best HMM Match : EGF (HMM E-Value=3.5e-06)                    33   3.3  
SB_5000| Best HMM Match : EGF_CA (HMM E-Value=0)                       33   3.3  
SB_1171| Best HMM Match : No HMM Matches (HMM E-Value=.)               33   3.3  
SB_58884| Best HMM Match : 7tm_2 (HMM E-Value=2.4e-29)                 33   3.3  
SB_52354| Best HMM Match : EGF (HMM E-Value=0.0011)                    33   3.3  
SB_31301| Best HMM Match : EGF (HMM E-Value=0.0037)                    33   3.3  
SB_29947| Best HMM Match : Fasciclin (HMM E-Value=2.3e-33)             33   3.3  
SB_20014| Best HMM Match : EGF_CA (HMM E-Value=1.6e-18)                33   3.3  
SB_12383| Best HMM Match : EGF_CA (HMM E-Value=2.5e-12)                33   3.3  
SB_10557| Best HMM Match : GCC2_GCC3 (HMM E-Value=7.2e-15)             33   3.3  
SB_58945| Best HMM Match : EGF_CA (HMM E-Value=3.6e-06)                33   4.4  
SB_49120| Best HMM Match : F5_F8_type_C (HMM E-Value=1.1e-08)          33   4.4  
SB_39098| Best HMM Match : EGF (HMM E-Value=5.2e-07)                   33   4.4  
SB_32896| Best HMM Match : F5_F8_type_C (HMM E-Value=8.6e-17)          33   4.4  
SB_31319| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.4  
SB_28523| Best HMM Match : EGF (HMM E-Value=2e-05)                     33   4.4  
SB_27922| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.4  
SB_21308| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.4  
SB_17959| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.4  
SB_10187| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.4  
SB_6365| Best HMM Match : No HMM Matches (HMM E-Value=.)               33   4.4  
SB_57056| Best HMM Match : EGF (HMM E-Value=0.13)                      33   4.4  
SB_53139| Best HMM Match : EGF (HMM E-Value=3.2e-08)                   33   4.4  
SB_50806| Best HMM Match : EGF_CA (HMM E-Value=1e-27)                  33   4.4  
SB_42216| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.4  
SB_41911| Best HMM Match : PAN (HMM E-Value=0.00033)                   33   4.4  
SB_36797| Best HMM Match : EGF (HMM E-Value=0.13)                      33   4.4  
SB_25329| Best HMM Match : EGF (HMM E-Value=0.13)                      33   4.4  
SB_16758| Best HMM Match : EGF_CA (HMM E-Value=5.5e-14)                33   4.4  
SB_14811| Best HMM Match : EGF (HMM E-Value=0.13)                      33   4.4  
SB_10956| Best HMM Match : EGF (HMM E-Value=5.3e-05)                   33   4.4  
SB_8486| Best HMM Match : Granulin (HMM E-Value=0)                     33   4.4  
SB_4118| Best HMM Match : EGF (HMM E-Value=1.8e-20)                    33   4.4  
SB_48360| Best HMM Match : EGF (HMM E-Value=0.1)                       32   5.8  
SB_38935| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   5.8  
SB_22969| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   5.8  
SB_22536| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   5.8  
SB_2600| Best HMM Match : Fibrinogen_C (HMM E-Value=0.00053)           32   5.8  
SB_52175| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   5.8  
SB_32488| Best HMM Match : EGF (HMM E-Value=2)                         32   5.8  
SB_29723| Best HMM Match : EGF_2 (HMM E-Value=0.55)                    32   5.8  
SB_28368| Best HMM Match : Pentaxin (HMM E-Value=9.5e-11)              32   5.8  
SB_25113| Best HMM Match : EGF (HMM E-Value=9.1e-07)                   32   5.8  
SB_24499| Best HMM Match : Fibrinogen_C (HMM E-Value=0.00053)          32   5.8  
SB_4088| Best HMM Match : No HMM Matches (HMM E-Value=.)               32   5.8  
SB_57668| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   7.6  
SB_42336| Best HMM Match : Sushi (HMM E-Value=1.5e-08)                 32   7.6  
SB_30275| Best HMM Match : EGF_CA (HMM E-Value=1.3e-13)                32   7.6  
SB_17844| Best HMM Match : Fibrinogen_C (HMM E-Value=0)                32   7.6  
SB_9160| Best HMM Match : EGF (HMM E-Value=0.0019)                     32   7.6  
SB_6741| Best HMM Match : WD40 (HMM E-Value=0)                         32   7.6  
SB_47980| Best HMM Match : EGF_CA (HMM E-Value=7.6e-20)                32   7.6  
SB_40322| Best HMM Match : RVT_1 (HMM E-Value=7.4e-27)                 32   7.6  
SB_33521| Best HMM Match : Utp14 (HMM E-Value=0.48)                    32   7.6  
SB_16854| Best HMM Match : UL97 (HMM E-Value=4.9)                      32   7.6  

>SB_18656| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 3292

 Score =  614 bits (1517), Expect = e-175
 Identities = 367/1115 (32%), Positives = 579/1115 (51%), Gaps = 72/1115 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            INVLD ND+ P+FE   Y A + E  S G  VL ++A+D D G N EV+Y I       L
Sbjct: 337  INVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCI-------L 389

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N +                F I   SGA+     LDREKV  YT+ V+A DQ +P     
Sbjct: 390  NSDGD-----------NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPR--- 435

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+T T+ + ++D ND  PQFS+K Y+ ++ ED+ V  N ++  ++ATD D G+N  + + 
Sbjct: 436  SATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV--NQLVTTVRATDCDQGSNGEVFFE 493

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ GN    FSI+ ++G+V + + LDYE +  + L++ AQD G P   N T + I + DV
Sbjct: 494  IVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDV 553

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDNAP+F +S FQ  + EN  +G    RVQAYD D G N E+T++    D      LP +
Sbjct: 554  NDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQND------LPFS 607

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G +    +LDRE   K+   + A D G P +  TA               F   +
Sbjct: 608  INENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEE 667

Query: 371  YEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGR-FSITSQNGRGLITVAQP 428
            Y   +AE+   GT V+ + A D D     + Y I   +   R F I   N +GLIT++  
Sbjct: 668  YHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRI---NPQGLITLSCT 724

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            L++  +  YV +VSA+D G  S TA+V +N+TD+N +AP F+   Y+A V EDA +GT+V
Sbjct: 725  LNYNTKHVYVFSVSASD-GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSV 783

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            L V ATD D G NA+I+YS+++ +          +F ++  TG I T   LDRE +  Y 
Sbjct: 784  LTVLATDRDTGSNAKISYSIATLVP---------EFSVDETTGVIKTAGSLDREKVDTYR 834

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
              VTA D G+P L   + V I + DVNDN+PVF +  Y A + ED   G  V +V A+DA
Sbjct: 835  FEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDA 894

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D+  N +I Y        +G+F ID   G+IRT K LDRE++  ++L  VA D GTPP  
Sbjct: 895  DIXKNAQIIYSFASNGDGQGTFTIDRTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQ 954

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            ++V V + +ED+ DSPP+FE       + E++P  + +  ++A   D  P   + YSI  
Sbjct: 955  ASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVR 1014

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
            G+    F +    G+    + T++ LDYE+ + +Y L +RA   P + +  V + + D+N
Sbjct: 1015 GNSPQVFDINPNTGA----IQTLMKLDYET-QSEYRLTVRATLSPFFTETTVMVYLKDIN 1069

Query: 789  DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848
            DN PV++ F +  N  +   P     ++PAYD DV+DKL ++++ GN    + LN T+G 
Sbjct: 1070 DNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPDVSDKLTFKVMEGNAKEWVTLNATSGE 1129

Query: 849  MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQF 908
            ++++ +L     K A ++++VTDG+    A   + +  +T EM+  SI + ++DM   +F
Sbjct: 1130 LSVNKKL-IQASKPANIKIAVTDGLRTASATGSIMMTSVTTEMIQQSIQLEIDDMEVLEF 1188

Query: 909  LSPLLGFFIDGLAAIIPCPKENIYIFSVQ-------DDTDVTGNILNVSFSARRPDAEVG 961
             +       + ++ I+ C  + + +F +           D +   L +    R+ + +  
Sbjct: 1189 FNTAYEKLRESVSQIVKCKPDQVLMFDITSRVILPVSSADYSKTRLTIWLVLRKKNEKEA 1248

Query: 962  VAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPC-----LNFEECLTV 1016
              G    ++  + +R  +YLHR  +A+   + ++ F D++C  +PC      ++ +C T 
Sbjct: 1249 FVG----YFDASFVRYVIYLHREQIAKEVGINLMAFPDDVCSKKPCNYLKPNSYYDCNTY 1304

Query: 1017 LKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
              F      ++S  V+FR +     F C CP  + G +C+T L    C +    +  + G
Sbjct: 1305 TYFSGEPQVLSSLKVVFRTVPVDMKFNCSCPADYRGQDCDTHLN--LCTLTHAATTEKQG 1362

Query: 1077 SQCVARREGGILCQGCSIDAAYTTAVCELRARSFP 1111
              C  + +      G   +A  T   C L+ R  P
Sbjct: 1363 FYCRCKADR----VGSRCEANVTRDFCPLKPRELP 1393



 Score =  367 bits (903), Expect = e-101
 Identities = 263/841 (31%), Positives = 412/841 (48%), Gaps = 55/841 (6%)

Query: 18   DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77
            ++ P F   Q +ASV E A  GT V T+ A+D D G N  + Y+        ++P     
Sbjct: 236  NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYS--------MSPSQNLM 287

Query: 78   XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137
                        F ID  +G + T+  LDRE + R+   VKA D   P    L     + 
Sbjct: 288  SATY--------FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEP---SLEGYMDLT 336

Query: 138  VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-T 196
            +N++D NDN P F    Y   + ED S+ D   +  ++A+DAD G+N  ++Y I+  +  
Sbjct: 337  INVLDVNDNGPIFERNIYAADIPEDKSIGD--FVLAVRASDADSGSNGEVKYCILNSDGD 394

Query: 197  QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
               FSI  +SG V+++K LD E+V +Y L ++AQD G+P RS T  + I + DVND  P+
Sbjct: 395  NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQ 454

Query: 257  FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
            F   ++  ++ E+VP+   +  V+A D D+G N E+ + +     +GN     +I+  +G
Sbjct: 455  FSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIV----SGNDMNFFSINRING 510

Query: 317  WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
             V    +LD E    + LLVTA D G P      T              F+   ++  + 
Sbjct: 511  EVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIP 570

Query: 377  EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
            E+   G     + A   D+D+  + EIT    +     +     G I++ + LD ++  +
Sbjct: 571  ENYAVGQEFYRVQA--YDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPK 628

Query: 437  YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
            +   + A D G   +  TA + I + D N+  P F    Y  S+ E++  GT+VL V A 
Sbjct: 629  FTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAI 688

Query: 495  DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
            D D G    + YS+ S       + HD+ F INPQ G IT +  L+  T   Y+ +V+A 
Sbjct: 689  DPDSG-PTNVVYSIVSS------SGHDRCFRINPQ-GLITLSCTLNYNTKHVYVFSVSAS 740

Query: 555  DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
            DG    LS T  V ++V D N + P FK++ Y+A + EDA +GTSV  V ATD D G N 
Sbjct: 741  DG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNA 797

Query: 615  RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            +I Y +     E   F +D  +GVI+T  +LDRE V T+  +  A D G P   +   V+
Sbjct: 798  KISYSIATLVPE---FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVY 854

Query: 675  IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSN 733
            I I D+ND+ PVF        + E+   G  + E+ A D D   NA + YS    GD   
Sbjct: 855  IHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIXKNAQIIYSFASNGDGQG 914

Query: 734  SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790
            +F+++  QG     + T+  LD E+   +YEL + A    +PP    V+V++++ DV D+
Sbjct: 915  TFTIDRTQGI----IRTLKPLDRET-IPEYELTVVATDQGTPPGQASVKVKVILEDVKDS 969

Query: 791  APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGS 848
             P+ +         +D  P  P   V A   D++ +  + Y I+ GN+  +  +N  TG+
Sbjct: 970  PPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGA 1029

Query: 849  M 849
            +
Sbjct: 1030 I 1030



 Score =  310 bits (761), Expect = 1e-83
 Identities = 256/826 (30%), Positives = 375/826 (45%), Gaps = 59/826 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN----- 144
           +R+D ++G L+ R SL      R   +V    Q+S  S R  S A + + I D       
Sbjct: 168 YRVDSKTGHLVLRKSLVGHP-ERIMFVVAQLSQSSKNSKRKKS-ARLRLFIDDGKQIKNN 225

Query: 145 ----------DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
                     +N PQFS      SV ED  V    V+A + A+D D G+N  IRY++   
Sbjct: 226 RRRVRKRAPTNNPPQFSRLQEDASVSEDAEV--GTVVATVSASDPDSGSNGMIRYSMSPS 283

Query: 195 NTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
              M    FSID ++G ++  + LD E +  +   ++A+DGG PS      L IN+ DVN
Sbjct: 284 QNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVN 343

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           DN P F  +++   + E+  IG  ++ V+A DAD G N E+ Y + + D   +     +I
Sbjct: 344 DNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSA---FSI 400

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
              SG V    +LDRE    Y L V A D G+PPRSAT T              F    Y
Sbjct: 401 GEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVY 460

Query: 372 EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
              + ED P    V T+ ATD D+  +  + +EI  GN    FSI   NG   + V Q L
Sbjct: 461 SATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGE--VRVKQKL 518

Query: 430 DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           D++    + L V+A D G     +   V I + D N+ AP F ++ +   + E+  +G  
Sbjct: 519 DYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQE 578

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
              V A D D G N +IT+S            +D  F IN  TG I+  + LDRE +  +
Sbjct: 579 FYRVQAYDKDHGTNGEITFSF---------MQNDLPFSINENTGGISIKEELDREKVPKF 629

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
              + ARD GVP    T  + I+++D+NDN P F Q+ Y  +I E++  GTSV QV A D
Sbjct: 630 TFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAID 689

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D G    + Y +      +  F I+P  G+I  +  L+  +   +     A DG     
Sbjct: 690 PDSGPT-NVVYSIVSSSGHDRCFRINP-QGLITLSCTLNYNTKHVYVFSVSASDG---ML 744

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           SST +V++ + D N   P F+    +  + E++ +GT++  + A D D G NA + YSI 
Sbjct: 745 SSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI- 803

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILV 784
                  FS++   G  K    T   LD E     Y   + A     P L     V I +
Sbjct: 804 -ATLVPEFSVDETTGVIK----TAGSLDREKV-DTYRFEVTATDHGIPQLKAKSFVYIHI 857

Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ--YRILS-GNNANLIL 841
            DVNDN PV           +D  P G    V A DAD+    Q  Y   S G+      
Sbjct: 858 ADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIXKNAQIIYSFASNGDGQGTFT 917

Query: 842 LNETTGSM-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
           ++ T G + TL P     +P+     V+   G    +A +++ V L
Sbjct: 918 IDRTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVIL 963



 Score =  284 bits (697), Expect = 6e-76
 Identities = 215/708 (30%), Positives = 337/708 (47%), Gaps = 48/708 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +LD ND +P F  + Y A++RE       V T++ATD D G N EV +  E+V+ + 
Sbjct: 442  KITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFF--EIVSGND 499

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +N                  F I+  +G +  +  LD E +  + +LV A D+  P    
Sbjct: 500  MN-----------------FFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPF--- 539

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L +  T+ + +ID NDN PQF    +   + E+ +V       +++A D D G N  I +
Sbjct: 540  LYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQE--FYRVQAYDKDHGTNGEITF 597

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            + +     + FSI+  +G +S+ + LD E+V  +   I+A+D G P +  T Q+ I + D
Sbjct: 598  SFM--QNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLD 655

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P+F    +  S++EN   G S+++V+A D D G    + Y++     +G+ D   
Sbjct: 656  INDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG-PTNVVYSIVSS--SGH-DRCF 711

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+P+ G +  S  L+  T+  Y   V+A+DG     S+TA               F   
Sbjct: 712  RINPQ-GLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRR 767

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y  E+ ED   GT V+T+ ATD D  +      +       FS+      G+I  A  L
Sbjct: 768  SYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETT--GVIKTAGSL 825

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D ++   Y   V+ATD G       + V I+I D N+  PVF    Y A V ED   G  
Sbjct: 826  DREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGR 885

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V+ VSA+D+D+  NAQI YS +S    +        F I+   G I T K LDRET+  Y
Sbjct: 886  VIEVSASDADIXKNAQIIYSFASNGDGQGT------FTIDRTQGIIRTLKPLDRETIPEY 939

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             LTV A D G P    +  V++ + DV D+ P+F++ LY   + ED    + V  V A  
Sbjct: 940  ELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKS 999

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             D+     + Y +  +      F I+P +G I+T   LD E+ + + L    +     P 
Sbjct: 1000 QDLSPETGMMYSI-VRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRL---TVRATLSPF 1055

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
             +   V + ++DIND+ PV E+  +   + E         +I A+DPD
Sbjct: 1056 FTETTVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPD 1103



 Score =  272 bits (666), Expect = 3e-72
 Identities = 164/577 (28%), Positives = 266/577 (46%), Gaps = 47/577 (8%)

Query: 1357 RFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKS---------GLLHYSYN 1407
            RF G  +L  N     I+LPW  +L  RTR+    ++  + +S         G L Y +N
Sbjct: 1744 RFIGQSILIKNYRTTSIKLPWSQSLMFRTRKSLGILIETRFRSSAGVLKVVNGRLSYQFN 1803

Query: 1408 GE-TMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466
             + T+ L    + DGAWH +++ WL   + VT DY  +         K++  +  ++++G
Sbjct: 1804 QQLTVNLSQLRVDDGAWHHVDVTWLRGMVRVTGDYIYQATATHQ-GEKLE--FTSELIMG 1860

Query: 1467 G---LDTTAGLLASDVGF-FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSIC 1522
            G   L+T+A    + +   F GC+  + +  +Q   ++ T +++V  GC   + C  S C
Sbjct: 1861 GRQSLNTSAPQPKAYIEEGFVGCMMGITVDGSQIDTSQAT-KQSVFTGCSMPSHCQSSPC 1919

Query: 1523 PPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARC-VPDQTPKGYSCACEPGYTL 1581
                 CV  WD+ +C C  G VG +C + C+L PC    C +   TPKGY C C P YT 
Sbjct: 1920 LGGGTCVEGWDTFSCRCRPGYVGKRCTNVCDLKPCQNGNCELSSATPKGYKCKCPPQYT- 1978

Query: 1582 TTSGCIESGKEECPGGWWGGS---ACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638
                C    +  C   ++  S    CGPC C V   ++P CNK  G+C+C   HY+    
Sbjct: 1979 -GEYCETRKETPCQDKFFSASNIGLCGPCNCPVGANFNPVCNKTTGECYCNPYHYRSPKG 2037

Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCP 1698
             ECL C C   GS +  C  + GQC C  G                       V+   CP
Sbjct: 2038 NECLKCNCEEIGSLSLQCRVSDGQCPCIKG--------------------SSTVINTSCP 2077

Query: 1699 RSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRK 1758
            RS A  +WW R  F       CP G+SG A R CD+ K   WQ PD+ +C + +F  LRK
Sbjct: 2078 RSIAEDIWWKRGAFDKIAEQKCPFGASGTARRICDKNKG--WQKPDLMDCVSNSFLNLRK 2135

Query: 1759 QLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLN 1818
            +L ++E G+L  +  + + +A  L  A     RLY  D+ +A   +  L DYE +Q    
Sbjct: 2136 KLKRLEEGKLLWSPSIAMDLARQLDLAITLATRLYPNDIDIALKAITVLFDYESQQNEST 2195

Query: 1819 LTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQHD 1878
            L  +++ ++ + L++S + + N E +  W  ++  +   A+L+ +K + +   LA +   
Sbjct: 2196 LVSAKNHEFAQILVQSASMLFNAENKNVWSVVQRNSAGTADLM-EKMENFSGTLANNLAH 2254

Query: 1879 TYTSPFEIVTKDVVISVDTVTSESIYGFEPTQLNRLN 1915
               + +    + ++     +T   +    P  +   N
Sbjct: 2255 LKRARYRRNVESIIPPYTVITPNILMELHPVTIRNFN 2291



 Score =  241 bits (589), Expect = 7e-63
 Identities = 200/724 (27%), Positives = 336/724 (46%), Gaps = 62/724 (8%)

Query: 4    PFCIHQ---QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
            PF  +Q    I ++D ND++P F    ++  + E  + G     ++A D+D G N E+  
Sbjct: 538  PFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEI-- 595

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
            T   +  D                     F I+  +G +  +  LDREKV ++T  +KA 
Sbjct: 596  TFSFMQNDL-------------------PFSINENTGGISIKEELDREKVPKFTFGIKAR 636

Query: 121  DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
            D+  P  +    TA I + ++D NDN P+FS++ Y  S+ E+     +  + ++KA D D
Sbjct: 637  DKGVPFKE---GTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTS--VLQVKAIDPD 691

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
             G  + + Y+I+  +   +    +  G ++L  TL+Y     Y   + A DG     S+T
Sbjct: 692  SGPTNVV-YSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDG---MLSST 747

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
              + +N+ D N +AP F    +   V E+  +G S++ V A D D G NA+++Y++    
Sbjct: 748  ALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI---- 803

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
                +    ++D  +G + T+G LDRE    Y+  VTATD G P   A +          
Sbjct: 804  --ATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVN 861

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418
                 F+   YE ++ ED  PG  V+ ++A+DAD  ++ ++ Y     N  G+ + T   
Sbjct: 862  DNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIXKNAQIIYSF-ASNGDGQGTFTIDR 920

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTA 476
             +G+I   +PLD +    Y LTV ATD G     A V++ +   D  +  P+FE   Y  
Sbjct: 921  TQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEV 980

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            +V ED P  + V+ V A   D+     + YS+          +  Q F INP TGAI T 
Sbjct: 981  TVPEDTPPRSPVITVKAKSQDLSPETGMMYSI-------VRGNSPQVFDINPNTGAIQTL 1033

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
              LD ET S Y LTV A     P  ++TT V + + D+NDN PV +      N+ E  + 
Sbjct: 1034 MKLDYETQSEYRLTVRATLS--PFFTETT-VMVYLKDINDNTPVLEAFHMNINVQEGKVP 1090

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
              +  ++ A D DV  + ++ +++   + +E    ++  SG +  NK L + S    ++K
Sbjct: 1091 PEARYKIPAYDPDV--SDKLTFKVMEGNAKEW-VTLNATSGELSVNKKLIQASKPA-NIK 1146

Query: 657  AVAIDG--GTPPQSSTVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAH 712
                DG        S ++  +  E I  S    + + + L F+ +    +  ++ +I   
Sbjct: 1147 IAVTDGLRTASATGSIMMTSVTTEMIQQSIQLEIDDMEVLEFFNTAYEKLRESVSQIVKC 1206

Query: 713  DPDE 716
             PD+
Sbjct: 1207 KPDQ 1210



 Score =  239 bits (585), Expect = 2e-62
 Identities = 159/432 (36%), Positives = 222/432 (51%), Gaps = 21/432 (4%)

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           N  P F      ASV EDA +GT V  VSA+D D G N  I YS+S   +  +  +    
Sbjct: 236 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATY---- 291

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F I+  TG ITT + LDRE +  +   V A DGG PSL    D+ I+V+DVNDN P+F++
Sbjct: 292 FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFER 351

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
            +Y A+I ED  +G  V  V A+DAD G NG + Y +   D +  +F I   SG +   K
Sbjct: 352 NIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMK 411

Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            LDRE V T+ L+  A D G PP+S+TV V I + D+ND  P F     +  I E+ P+ 
Sbjct: 412 KLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVN 471

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             +  +RA D D+G N  V + I  G+D N FS+    G    E+     LDYE     +
Sbjct: 472 QLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRING----EVRVKQKLDYEM-IGVF 526

Query: 764 ELVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVG-PFGRVP 817
            L++ A     P L+N   V+I + DVNDNAP  V   FQ +     + + VG  F RV 
Sbjct: 527 NLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMI---PENYAVGQEFYRVQ 583

Query: 818 AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTD-GVNE 875
           AYD D     +       N     +NE TG +++  +L+   VPK  T  +   D GV  
Sbjct: 584 AYDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPKF-TFGIKARDKGVPF 642

Query: 876 IKAMMQLSVRLI 887
            +   Q+++ L+
Sbjct: 643 KEGTAQITITLL 654



 Score =  237 bits (581), Expect = 7e-62
 Identities = 205/712 (28%), Positives = 312/712 (43%), Gaps = 34/712 (4%)

Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
           K    D+  G +  +R +++G   ++ F +  LS      K    ++    RL I   D 
Sbjct: 166 KFYRVDSKTG-HLVLRKSLVGHPERIMFVVAQLSQSS---KNSKRKKSARLRLFI---DD 218

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
           G   ++N  +  +  R   +N P+F       SVSE+  +G  +  V A D D G N  +
Sbjct: 219 GKQIKNNRRR--VRKRAPTNNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMI 276

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
            Y+M+      +     +ID  +G + T   LDRE   ++   V A DGG+P        
Sbjct: 277 RYSMSPSQNLMSATY-FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDL 335

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412
                        F    Y  ++ ED+  G  V+ + A+DAD  +    +    N+ G  
Sbjct: 336 TINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDN 395

Query: 413 SITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469
           S  S     G +TV + LD ++   Y L V A D G   RS T  V+I + D N+  P F
Sbjct: 396 SAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQF 455

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INP 528
               Y+A++ ED P+   V  V ATD D G N ++ +        E V+ +D  F  IN 
Sbjct: 456 SKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFF--------EIVSGNDMNFFSINR 507

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
             G +   + LD E +  + L VTA+D G P L + T V+I+++DVNDN P F    +  
Sbjct: 508 INGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQT 567

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            I E+  VG    +V A D D G NG I +     D     F I+  +G I   + LDRE
Sbjct: 568 MIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDL---PFSINENTGGISIKEELDRE 624

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            V        A D G P +  T  + I + DIND+PP F  +     I+ENS  GT++ +
Sbjct: 625 KVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQ 684

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVI 767
           ++A DPD GP  VV+  +        F +   QG     L+T+   L+Y + +  Y   +
Sbjct: 685 VKAIDPDSGPTNVVYSIVSSSGHDRCFRINP-QG-----LITLSCTLNYNT-KHVYVFSV 737

Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827
            A+   L +   V + VTD N +AP  K         +D         V A D D     
Sbjct: 738 SASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNA 797

Query: 828 QYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878
           +             ++ETTG +  +  L+         EV+ TD G+ ++KA
Sbjct: 798 KISYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKA 849



 Score =  181 bits (441), Expect = 6e-45
 Identities = 107/321 (33%), Positives = 159/321 (49%), Gaps = 37/321 (11%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDG---------DGSICRSGSQCVARREGGILCQGC 1092
            F C+C     G  CE  +T+  C +             + C +G+QC+ +  GG  C  C
Sbjct: 1363 FYCRCKADRVGSRCEANVTRDFCPLKPRELPKVNQMKWNPCMNGAQCINQPGGGFGCL-C 1421

Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERH 1152
                   T  CEL   SF    +  F  L ++ R+H+ L+F T  +  LLLYNG++N++ 
Sbjct: 1422 EDSNKADTPFCELTTLSFRDGDYAAFTALSQKWRLHISLQFTTLQSDALLLYNGQFNDKQ 1481

Query: 1153 DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTITM 1210
            DF+A+EL         G  +RF+ S GG  +  T  V+G + DG WH++   Y N+T  +
Sbjct: 1482 DFIAIEL--------SGGQVRFTVSTGGTPASATSRVDGGLNDGRWHSLTAVYKNKTAIV 1533

Query: 1211 ILDDCDKVLSLAGAADFGLK---YACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGL 1267
            I+DDC     LA A  FG +   Y CA   R           +   R L LT PL +GGL
Sbjct: 1534 IIDDC----KLAVAVQFGTQEGSYGCAAAKRL---------NQQAARSLQLTSPLMLGGL 1580

Query: 1268 PNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAE 1327
             ++ S + + +K + GC+ +  IDHK +DL + +   GT   C  K   C ++PC  G  
Sbjct: 1581 HSLRSEYPITSKRYTGCLRNVSIDHKRLDLAAPIWKRGTSPKCSIKVDFCRNSPCKRG-N 1639

Query: 1328 CSDLWDTYICDCKEGHTGKDC 1348
            C++ W TY+C C E + GK C
Sbjct: 1640 CTNTWGTYLCRCPENYGGKQC 1660



 Score = 75.4 bits (177), Expect = 6e-13
 Identities = 51/171 (29%), Positives = 94/171 (54%), Gaps = 21/171 (12%)

Query: 2159 NATGVGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWS----TLRGSGEWS 2214
            N+  V  KM   +  ++L +PI +  +   NR+   +R+   CV W+      RG G WS
Sbjct: 2367 NSDVVSVKM-PGMEDVQLAEPIHITFY---NRQV--NRSEYLCVFWNYSVPNTRGGG-WS 2419

Query: 2215 RVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFS 2274
              GC   I  +W+  +       C CNH+++FAVL D +++EF P+ +    + +Y   +
Sbjct: 2420 TNGCR-RIAINWTHTT-------CACNHMTSFAVLSD-LNLEFPPQVAFALRIGTYIGIA 2470

Query: 2275 ISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTS 2325
            +S+ +LL ++ +   +RG   + +N IHK+L+ ++ +AE+++L  +  RTS
Sbjct: 2471 VSVAILLIAFVSFVCLRGLKKSNANDIHKNLVAAIVIAEIIFLAGIN-RTS 2520



 Score = 62.5 bits (145), Expect = 5e-09
 Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 6/99 (6%)

Query: 1256 LDLTGPLQIGGLPNIPSSF-QVK---NKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCP 1311
            L+ T  L +GG  ++ +S  Q K    + FVGC+    +D   ID  S         GC 
Sbjct: 1851 LEFTSELIMGGRQSLNTSAPQPKAYIEEGFVGCMMGITVDGSQID-TSQATKQSVFTGC- 1908

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
               S C S+PC  G  C + WDT+ C C+ G+ GK C +
Sbjct: 1909 SMPSHCQSSPCLGGGTCVEGWDTFSCRCRPGYVGKRCTN 1947



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 2/92 (2%)

Query: 1458 QYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRAD- 1516
            Q    +++GGL +           + GC+++V I   +  L  P  +      C  + D 
Sbjct: 1570 QLTSPLMLGGLHSLRSEYPITSKRYTGCLRNVSIDHKRLDLAAPIWKRGTSPKCSIKVDF 1629

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548
            C  S C     C  +W +  C C     G QC
Sbjct: 1630 CRNSPC-KRGNCTNTWGTYLCRCPENYGGKQC 1660


>SB_22798| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 3255

 Score =  434 bits (1069), Expect = e-121
 Identities = 291/825 (35%), Positives = 426/825 (51%), Gaps = 55/825 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ P F    Y  +V E  ++G  V  + ATD D G N ++ Y+I       
Sbjct: 891  KVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSI------- 943

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+  +               F +D  +G + TR  LDRE +A Y++ + A D  S V  R
Sbjct: 944  LSGNENMA------------FAMDRFTGEITTRVPLDRETIASYSLTINA-DDGSLV--R 988

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              +  T++++I D+NDN P F+  +   ++ ED S T   V  ++ ATD D+G N A+ Y
Sbjct: 989  FMAATTVNISIADENDNQPTFTGPS-RFNISED-SPTGTRV-GQLTATDRDIGPNGAVTY 1045

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            AII GN    F +D  SG +S+  TLD E + SY LV++A D GSP +S T  + +++ D
Sbjct: 1046 AIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLD 1105

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAPRF  SLF   + E+  +  ++++V+  D DEG N  +T ++     +G      
Sbjct: 1106 VNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL-----SGEGSDNF 1160

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            TID  +G+V +   LD ET A YQL VTA DGG P +SATA               F+  
Sbjct: 1161 TID-STGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSP 1219

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
                 + ED    T VV L ATD+D    L ++I  GN    F I   +  GLI+VA+ L
Sbjct: 1220 AQVTSIPEDVAINTHVVKLNATDSD-GTPLTFDIVEGNAGSSFKIDQSS--GLISVAKRL 1276

Query: 430  DFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D +    Y L V AT++G + ++      I + D N+ APVF    Y  S+ E+ PIG T
Sbjct: 1277 DRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQT 1336

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V  V+ATD D G NA++TY LS             +F +NP TG +TT + LDRE  + Y
Sbjct: 1337 VAKVTATDRDEGENAKVTYELS--------VGDTSKFEVNPATGLVTTKRPLDREDQASY 1388

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             L VTA D G PS S    + +++ D+NDN P F Q  YT  + E+   G+++ +V A+D
Sbjct: 1389 SLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASD 1448

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             D G NGR+ Y +        +F ID  +G I     +DRE++A+++L   A D G PP 
Sbjct: 1449 PDAGANGRVTYSI-ISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPW 1507

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
             ST  V I + D ND+ P+F S+  ++ I E   IG+ +  + A D DEG NA V YSI 
Sbjct: 1508 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV 1567

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVEILVTD 786
             GD S +F++    G     L    +++ E+ P + Y   +R  S    + + V    +D
Sbjct: 1568 RGDTS-AFAINAMNG----VLTVKKEINRETVPTQSYIGSVRENSAQSTSVLTVAADDSD 1622

Query: 787  VNDNAPVMKDFQIIFNNYKDCFPVGPFGRV--PAYDADVTDKLQY 829
            V  NA V++ + II  N +  F +     V       D  +K QY
Sbjct: 1623 VGANA-VLR-YSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQY 1665



 Score =  420 bits (1034), Expect = e-117
 Identities = 285/788 (36%), Positives = 394/788 (50%), Gaps = 77/788 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND++P F +  Y+  V E  + G+ V  L A D D+G NA + Y+  LV+ DT
Sbjct: 396  KITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYS--LVSGDT 453

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F +D + G + T+ + DRE  A Y V ++A D  SP    
Sbjct: 454  ------------------SYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSP---S 491

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S  AT+ + I+D NDN P FS   YT SVDED+++     +  + A+D D G N+ +RY
Sbjct: 492  RSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAI--GAAMVTVTASDKDNGNNADLRY 549

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +   GNT   F++D+++G V++ ++LD+EQ  SY L +   D GSP  ++T+ LLIN+ D
Sbjct: 550  SFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVND 609

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P F  S +Q  V EN P G    +V A D D   N  L + +      GN D   
Sbjct: 610  INDNPPVFSPSAYQSRVKENTPAG---TQVSATDRDSSTNGALVFGI----IKGNDDGVF 662

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            TID  +G +  +   D E + +Y L V A D G P +  TA               F P 
Sbjct: 663  TIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPS 722

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y  ++ E    G+ VVTLTATD D                         RG I V+  L
Sbjct: 723  NYSKQIPESTVIGSTVVTLTATDLD----------------------SGPRGSIRVSSEL 760

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D +    Y L V A D G   RS +  V I + D N+ +P+F+  PY   V E +  G  
Sbjct: 761  DRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQ-GPYVFRVSESSSPGHQ 819

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            +  V+ATD+D   N  + Y+LS          +   F IN  TG IT    LD E  + Y
Sbjct: 820  IGQVAATDADDSSNGDVRYALSD---------NTDVFSINTSTGLITLKTQLDYEKKTQY 870

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            ++TVTA+DGG PS S  T V++ V DVNDN P F + LYT  + E+   G +V  V ATD
Sbjct: 871  MVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATD 930

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            AD G NG+I Y +     E  +F +D  +G I T   LDRE++A++ L   A DG     
Sbjct: 931  ADSGANGKISYSI-LSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRF 989

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
             +   V+I I D ND+ P F      F ISE+SP GT +G++ A D D GPN  V Y+I 
Sbjct: 990  MAATTVNISIADENDNQPTFTGPS-RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAII 1048

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784
             G+  NSF L+ R G     L     LD E+    Y LV++A+   SP       + + V
Sbjct: 1049 SGNQGNSFQLDPRSGI----LSVRSTLDRET-IPSYTLVVKASDAGSPQQSITASIHVSV 1103

Query: 785  TDVNDNAP 792
             DVNDNAP
Sbjct: 1104 LDVNDNAP 1111



 Score =  410 bits (1009), Expect = e-113
 Identities = 276/867 (31%), Positives = 439/867 (50%), Gaps = 78/867 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +LD ND+ PVF   QY ASV E  + G  ++T+ A+D+D G NA++ Y+    T+  
Sbjct: 499  EIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSF---TSGN 555

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N                  F +D  +G +    SLD E+ + Y + +  TD+ SP    
Sbjct: 556  TN----------------HAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSP---P 596

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+ T+ + +N+ D NDN P FS   Y   V E     + P   ++ ATD D   N A+ +
Sbjct: 597  LTDTSHLLINVNDINDNPPVFSPSAYQSRVKE-----NTPAGTQVSATDRDSSTNGALVF 651

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             II GN    F+ID  +G +S+ K+ DYE    Y L ++A+D G P + +T Q+ I I D
Sbjct: 652  GIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIED 711

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VND++P F  S + + + E+  IG ++V + A D D G                      
Sbjct: 712  VNDHSPVFSPSNYSKQIPESTVIGSTVVTLTATDLDSG---------------------- 749

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
               PR G +  S +LDRET   Y L V A DGG   RS++                F  G
Sbjct: 750  ---PR-GSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQ-G 804

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y   ++E   PG  +  + ATDAD+ +         +    FSI +    GLIT+   L
Sbjct: 805  PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTST--GLITLKTQL 862

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D++++ +Y++TV+A D G   RS   +V++ + D N+  P F  + YT +V E+   G  
Sbjct: 863  DYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVA 922

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V  V+ATD+D G N +I+YS+ S   NE +A     F ++  TG ITT   LDRET++ Y
Sbjct: 923  VCYVTATDADSGANGKISYSILS--GNENMA-----FAMDRFTGEITTRVPLDRETIASY 975

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             LT+ A DG +      T V IS+ D NDN+P F       NI ED+  GT V Q+ ATD
Sbjct: 976  SLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP-SRFNISEDSPTGTRVGQLTATD 1034

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             D+G NG + Y +     +  SF +DP SG++     LDRE++ ++ L   A D G+P Q
Sbjct: 1035 RDIGPNGAVTYAI-ISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQ 1093

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            S T  +H+ + D+ND+ P FE    +  I E++ + +T+ +++  D DEG N  +  S+ 
Sbjct: 1094 SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL- 1152

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784
             G+ S++F++++        +++   LDYE+    Y+L + A    SP      +V+I +
Sbjct: 1153 SGEGSDNFTIDS-----TGFVLSKTPLDYET-TAAYQLTVTARDGGSPSKSATAQVKITI 1206

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844
             +VNDN P       + +  +D        ++ A D+D T  L + I+ GN  +   +++
Sbjct: 1207 INVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGT-PLTFDIVEGNAGSSFKIDQ 1265

Query: 845  TTGSMTLSPQLNTNVPKLATMEVSVTD 871
            ++G ++++ +L+       T+ V  T+
Sbjct: 1266 SSGLISVAKRLDRETTANYTLVVRATE 1292



 Score =  380 bits (934), Expect = e-104
 Identities = 262/767 (34%), Positives = 393/767 (51%), Gaps = 43/767 (5%)

Query: 94   GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEK 153
            G  G++   + LDRE    Y++ V+A D  S  + R SST  + + + D NDN P F + 
Sbjct: 749  GPRGSIRVSSELDRETTPSYSLQVEARDGGS--TSRSSSTR-VTIALQDINDNSPIF-QG 804

Query: 154  TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213
             Y   V E  S +    I ++ ATDAD  +N  +RYA+   NT + FSI++ +G ++L  
Sbjct: 805  PYVFRVSE--SSSPGHQIGQVAATDADDSSNGDVRYAL-SDNTDV-FSINTSTGLITLKT 860

Query: 214  TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273
             LDYE+   Y + + A+DGG+PSRS+ T + + + DVNDN P+F  SL+  +V EN+  G
Sbjct: 861  QLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAG 920

Query: 274  YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333
             ++  V A DAD G N +++Y++     +GN ++   +D  +G + T   LDRET A Y 
Sbjct: 921  VAVCYVTATDADSGANGKISYSI----LSGNENMAFAMDRFTGEITTRVPLDRETIASYS 976

Query: 334  LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
            L + A D G   R   AT                 G     ++ED P GT V  LTATD 
Sbjct: 977  LTINA-DDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTRVGQLTATDR 1035

Query: 394  D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--R 449
            D   +  + Y I  GN    F +  ++  G+++V   LD +    Y L V A+D+G   +
Sbjct: 1036 DIGPNGAVTYAIISGNQGNSFQLDPRS--GILSVRSTLDRETIPSYTLVVKASDAGSPQQ 1093

Query: 450  SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
            S TA + +++ D N+ AP FE + ++  + EDA + +TVL V   D D G N  IT SLS
Sbjct: 1094 SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLS 1153

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
             E S+         F I+  TG + +   LD ET + Y LTVTARDGG PS S T  V+I
Sbjct: 1154 GEGSD--------NFTID-STGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKI 1204

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            ++++VNDN P F       +I ED  + T V ++ ATD+D      + +++  +     S
Sbjct: 1205 TIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD---GTPLTFDI-VEGNAGSS 1260

Query: 630  FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
            F ID +SG+I   K LDRE+ A + L   A + G+  +S      I++ D+ND+ PVF  
Sbjct: 1261 FKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNP 1320

Query: 690  DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
                  + EN PIG T+ ++ A D DEG NA V Y +  GD S  F +    G     + 
Sbjct: 1321 GSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTS-KFEVNPATGL----VT 1375

Query: 750  TMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
            T   LD E  +  Y L + A     P       + + + D+NDN+P     +      ++
Sbjct: 1376 TKRPLDRED-QASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTEN 1434

Query: 807  CFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL 851
                    RV A D D     ++ Y I+SGN+ N   ++ TTG +T+
Sbjct: 1435 TANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITV 1481



 Score =  350 bits (861), Expect = 8e-96
 Identities = 277/877 (31%), Positives = 428/877 (48%), Gaps = 102/877 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+V D ND++P F +  Y  ++RE   +    + + ATD+D G NA + Y++        
Sbjct: 195 IDVKDENDNAPEFPLNSYVFNIRENTPAAQVAI-VTATDRDSGTNAAITYSL-------- 245

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           ++ F ++ ++G + T   LD E    YT+ + A D       + 
Sbjct: 246 -------------FSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFD------GKH 286

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGANSA 186
           ++   + +NI+D N+  P+F +   T   D   +V +    N  I  + ATD D     +
Sbjct: 287 TTFVPLVINILDVNEP-PRFQDDC-TRRGDCSATVLESAPLNTRIVTLAATDPD---GDS 341

Query: 187 IRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           + Y++ I  + +  F+ID+ SG ++L K LD E   +Y LV+ A DG   +      L I
Sbjct: 342 LLYSVRIRDSQEKIFTIDN-SGRLTLNKMLDREAKSAYDLVVEASDGNIIA---IAALKI 397

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            + DVNDNAP F  S+++  V E+V +G  + ++ A D D G+NA L+Y++   D +   
Sbjct: 398 TVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSY-- 455

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
               T+D + G + T G  DRET+A YQ+ + A DGG P RS  AT              
Sbjct: 456 ---FTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPV 511

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLI 423
           F   QY   + ED   G  +VT+TA+D D  N   L Y  T GNT   F++ +  G  ++
Sbjct: 512 FSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTG--VV 569

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481
           TV++ LDF+Q   Y L +S TD G    +DT+ + IN+ D N+  PVF  + Y + V E+
Sbjct: 570 TVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKEN 629

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            P GT V   SATD D   N  + + +          + D  F I+  TG I+  K  D 
Sbjct: 630 TPAGTQV---SATDRDSSTNGALVFGIIK-------GNDDGVFTIDGSTGIISIAKSPDY 679

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
           E  + Y LTV ARD GVP   DT  V I + DVND+ PVF    Y+  I E  ++G++V 
Sbjct: 680 ENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVV 739

Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            + ATD D G          P+             G IR +  LDRE+  ++ L+  A D
Sbjct: 740 TLTATDLDSG----------PR-------------GSIRVSSELDRETTPSYSLQVEARD 776

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
           GG+  +SS+  V I ++DIND+ P+F+   + F +SE+S  G  IG++ A D D+  N  
Sbjct: 777 GGSTSRSSSTRVTIALQDINDNSPIFQGPYV-FRVSESSSPGHQIGQVAATDADDSSNGD 835

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRA---ASPPLWND 777
           V Y++   D+++ FS+ T  G     L+T+   LDYE  + +Y + + A    +P   + 
Sbjct: 836 VRYALS--DNTDVFSINTSTG-----LITLKTQLDYEK-KTQYMVTVTAKDGGTPSRSSL 887

Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGN 835
             V+++V DVNDN P            ++         V A DAD     K+ Y ILSGN
Sbjct: 888 TVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGN 947

Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                 ++  TG +T    L+       ++ ++  DG
Sbjct: 948 ENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDG 984



 Score =  347 bits (853), Expect = 8e-95
 Identities = 274/877 (31%), Positives = 417/877 (47%), Gaps = 95/877 (10%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  INV D ND+ PVF    Y++ V+E   +GT V    ATD+D   N  + + I     
Sbjct: 602  HLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQV---SATDRDSSTNGALVFGI----- 653

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              +   D              VF IDG +G +    S D E   RY + V+A D+  PV 
Sbjct: 654  --IKGND------------DGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVK 699

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
                 TA + + I D ND+ P FS   Y+  + E  S      +  + ATD D G   +I
Sbjct: 700  ---YDTAQVTIFIEDVNDHSPVFSPSNYSKQIPE--STVIGSTVVTLTATDLDSGPRGSI 754

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            R +                        LD E   SY L + A+DGGS SRS++T++ I +
Sbjct: 755  RVS----------------------SELDRETTPSYSLQVEARDGGSTSRSSSTRVTIAL 792

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            +D+NDN+P  +   +   VSE+   G+ I +V A DAD+  N ++ Y ++D     N D+
Sbjct: 793  QDINDNSP-IFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSD-----NTDV 846

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +I+  +G +    QLD E + +Y + VTA DGG P RS+                 F 
Sbjct: 847  -FSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFA 905

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y   + E+   G  V  +TATDAD   + ++ Y I  GN    F++    G   IT 
Sbjct: 906  KSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGE--ITT 963

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
              PLD +    Y LT++A D           V I+I D N+  P F   P   ++ ED+P
Sbjct: 964  RVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTF-TGPSRFNISEDSP 1022

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT V  ++ATD D+G N  +TY++ S        +    F ++P++G ++    LDRET
Sbjct: 1023 TGTRVGQLTATDRDIGPNGAVTYAIIS-------GNQGNSFQLDPRSGILSVRSTLDRET 1075

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            +  Y L V A D G P  S T  + +SV+DVNDN P F++ L++  I EDA V ++V QV
Sbjct: 1076 IPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQV 1135

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
               D D G NG I   L  +  +  +F ID ++G + +   LD E+ A + L   A DGG
Sbjct: 1136 KVEDKDEGSNGAITLSLSGEGSD--NFTID-STGFVLSKTPLDYETTAAYQLTVTARDGG 1192

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            +P +S+T  V I I ++ND+ P F S      I E+  I T + ++ A D D  P   + 
Sbjct: 1193 SPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTP---LT 1249

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAA-----SPPLWND 777
            + I  G+  +SF ++   G     L+++   LD E+    Y LV+RA         ++N+
Sbjct: 1250 FDIVEGNAGSSFKIDQSSG-----LISVAKRLDRET-TANYTLVVRATETGSQGESVYNN 1303

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSG 834
              + +L  DVNDNAPV        + +++  P+G    +V A D D  +  K+ Y +  G
Sbjct: 1304 ATIRVL--DVNDNAPVFNPGSYAKSLHEN-LPIGQTVAKVTATDRDEGENAKVTYELSVG 1360

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            + +    +N  TG +T    L+       ++ V+  D
Sbjct: 1361 DTSK-FEVNPATGLVTTKRPLDREDQASYSLRVTAMD 1396



 Score =  325 bits (799), Expect = 3e-88
 Identities = 256/799 (32%), Positives = 387/799 (48%), Gaps = 78/799 (9%)

Query: 87  QDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           Q +F ID  +G++ T     DRE  +RY + V A D A+           + +++ D+ND
Sbjct: 146 QGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCH---KGRTVVVIDVKDEND 202

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
           N P+F   +Y  ++ E+   T    +A + ATD D G N+AI Y++  G  +  F ++S 
Sbjct: 203 NAPEFPLNSYVFNIREN---TPAAQVAIVTATDRDSGTNAAITYSLFSGENK--FMMNSK 257

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE- 264
           +G++  V  LD+E   SY + I A DG     +    L+INI DVN+  PRF     +  
Sbjct: 258 TGEIRTVTPLDHETKDSYTMRISAFDG---KHTTFVPLVINILDVNE-PPRFQDDCTRRG 313

Query: 265 ----SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
               +V E+ P+   IV + A D D      L Y++  +D    +    TID  SG +  
Sbjct: 314 DCSATVLESAPLNTRIVTLAATDPD---GDSLLYSVRIRDSQEKI---FTID-NSGRLTL 366

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           +  LDRE ++ Y L+V A+DG      A A               F    Y+  + ED  
Sbjct: 367 NKMLDREAKSAYDLVVEASDGNI---IAIAALKITVDDVNDNAPFFALSVYKTGVYEDVA 423

Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
            G+ V  LTA D D   + RL Y +  G+T   F++ SQ   G+I      D + +  Y 
Sbjct: 424 VGSIVRQLTAVDLDVGINARLSYSLVSGDT-SYFTVDSQ---GVIRTKGAFDRETKASYQ 479

Query: 439 LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           + + A D G   RS  A V+I I D N+  PVF +A YTASV ED  IG  ++ V+A+D 
Sbjct: 480 VALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDK 539

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G NA + YS +S  +N A       F ++  TG +T ++ LD E  S Y L ++  D 
Sbjct: 540 DNGNNADLRYSFTSGNTNHA-------FTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDR 592

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
           G P L+DT+ + I+V D+NDN PVF    Y + + E+   GT   QV ATD D   NG +
Sbjct: 593 GSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGAL 649

Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
            + +  K  ++G F ID ++G+I   K+ D E+   +DL   A D G P +  T  V I 
Sbjct: 650 VFGII-KGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIF 708

Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGDDSNSF 735
           IED+ND  PVF     +  I E++ IG+T+  + A D D GP   +  S +   + + S+
Sbjct: 709 IEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTLTATDLDSGPRGSIRVSSELDRETTPSY 768

Query: 736 SL--ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793
           SL  E R G   +                     R++S       RV I + D+NDN+P+
Sbjct: 769 SLQVEARDGGSTS---------------------RSSS------TRVTIALQDINDNSPI 801

Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853
            +    +F   +   P    G+V A DAD +     R    +N ++  +N +TG +TL  
Sbjct: 802 FQG-PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKT 860

Query: 854 QLNTNVPKLATMEVSVTDG 872
           QL+        + V+  DG
Sbjct: 861 QLDYEKKTQYMVTVTAKDG 879



 Score =  308 bits (755), Expect = 6e-83
 Identities = 202/649 (31%), Positives = 328/649 (50%), Gaps = 41/649 (6%)

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F++ +Y+ SV E++  T N +        + V  N  +RY+I+ GN Q  F+IDS +G +
Sbjct: 106 FAKDSYSASVKEELQATQNVI-----TVSSSVSPN--LRYSIMDGNDQGMFTIDSSTGSI 158

Query: 210 SLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           +   +  D E    YRL + AQD  +      T ++I+++D NDNAP F  + +  ++ E
Sbjct: 159 TTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRE 218

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
           N P    +  V A D D G NA +TY++    ++G  +    ++ ++G + T   LD ET
Sbjct: 219 NTPAA-QVAIVTATDRDSGTNAAITYSL----FSG--ENKFMMNSKTGEIRTVTPLDHET 271

Query: 329 QAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           +  Y + ++A DG                            G     + E  P  T +VT
Sbjct: 272 KDSYTMRISAFDGKHTTFVPLVINILDVNEPPRFQDDCTRRGDCSATVLESAPLNTRIVT 331

Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
           L ATD D D+ L Y +   +++ +      +GR  +T+ + LD + +  Y L V A+D G
Sbjct: 332 LAATDPDGDSLL-YSVRIRDSQEKIFTIDNSGR--LTLNKMLDREAKSAYDLVVEASD-G 387

Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
                A ++I + D N+ AP F  + Y   V+ED  +G+ V  ++A D DVGINA+++YS
Sbjct: 388 NIIAIAALKITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYS 447

Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
           L        V+     F ++ Q G I T    DRET + Y + + A+DGG PS S    V
Sbjct: 448 L--------VSGDTSYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATV 498

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
           EI ++DVNDN PVF    YTA++ ED  +G ++  V A+D D G N  + Y     +   
Sbjct: 499 EIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNH 558

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
            +F +D  +GV+  +++LD E  +++ L     D G+PP + T  + I + DIND+PPVF
Sbjct: 559 -AFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVF 617

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
                   + EN+P GT   ++ A D D   N  + + I  G+D   F+++   G     
Sbjct: 618 SPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGI---- 670

Query: 748 LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPV 793
           +      DYE+ + +Y+L ++A     P  ++  +V I + DVND++PV
Sbjct: 671 ISIAKSPDYEN-KTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPV 718



 Score =  302 bits (741), Expect = 3e-81
 Identities = 261/846 (30%), Positives = 399/846 (47%), Gaps = 107/846 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+SP F   +Y  +V E  ++G+ +L + A+D D G N  V Y+I  ++ +  
Sbjct: 1410 LTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSI--ISGNHG 1467

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                  FRID  +G +     +DRE +A Y + + A D   P     
Sbjct: 1468 N-----------------AFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPP---W 1507

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             STA + + + D+NDN P F+    +  +DE +S+     +A + ATD D          
Sbjct: 1508 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSR--VAVVTATDRDE--------- 1556

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
              G N Q+ +SI  + GD S                I A +G          +L   +++
Sbjct: 1557 --GSNAQVFYSI--VRGDTSA-------------FAINAMNG----------VLTVKKEI 1589

Query: 251  N-DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            N +  P   T  +  SV EN     S++ V A D+D G NA L Y++     +GN +   
Sbjct: 1590 NRETVP---TQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSII----SGNDEKRF 1642

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  SG + T+  LD E +++Y L VTATD      +A                 F   
Sbjct: 1643 KINSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQ 1699

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y   + E+ P  T VV ++A+D D      Y I GG    +FSI  ++G  +I+ A  L
Sbjct: 1700 NYTASVRENSPTSTSVVKVSASDRDS-----YSIVGGKDSDKFSIDQRSG--IISTADVL 1752

Query: 430  DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D +    Y + V  TD+G    S+   V I I D N+ +P F+++ Y++S+ E++   + 
Sbjct: 1753 DRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSF 1812

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
               ++ATD+D G NA+ITY+LS    N+A       F+I   +G IT  + LDRE +S Y
Sbjct: 1813 SFKLAATDADEGTNARITYNLSR---NDA-------FMIGASSGVITNVRKLDREQVSIY 1862

Query: 548  LLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
             L V A D G P L S+   V I V D NDN P F       N+ E+A+VG  ++++ A 
Sbjct: 1863 TLYVQAVDQGNPRLASEWVPVHIRVQDENDNAPRFVSS-GNCNVSENAVVGAIIAELLAV 1921

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D+G  G + Y +  +  E   F ID  +GVI   + LDRE+ +T+DL   A D GTPP
Sbjct: 1922 DPDLGTGGVVSYRILTRQTE---FTIDNTTGVITLAQPLDRENKSTYDLAIQARDHGTPP 1978

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            Q+S++ + + + DIND  P+  S  L   + EN P  T +  I A D D G NA + +S+
Sbjct: 1979 QASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSL 2038

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEIL 783
               +  + F+L+   G    ++ T V LD E  +  Y L I  A   +P L +   V I 
Sbjct: 2039 LSNEHKSVFTLDNTTG----DISTKVPLDREQ-QAVYTLRIGVADKGNPSLSSVADVIID 2093

Query: 784  VTDVNDNAPVMKDFQIIFN-NYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLIL 841
            V D +DN P  +  +  +N    +  P G    +V A D D      Y I S   +    
Sbjct: 2094 VIDEDDNCPRFQPTE--YNVTISESLPRGASIVQVTARDIDGDKDTSYAIKSMTPSGGFT 2151

Query: 842  LNETTG 847
            ++  TG
Sbjct: 2152 IDSKTG 2157



 Score =  284 bits (697), Expect = 6e-76
 Identities = 225/708 (31%), Positives = 329/708 (46%), Gaps = 57/708 (8%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S+   IH  ++VLD ND++P FE   +   +RE AS  +TVL +K  D+D G N  +   
Sbjct: 1094 SITASIH--VSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITL- 1150

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
                   +L+ E +            D F ID  +G +L++  LD E  A Y + V A D
Sbjct: 1151 -------SLSGEGS------------DNFTIDS-TGFVLSKTPLDYETTAAYQLTVTARD 1190

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
              SP     S+TA + + II+ NDN P F       S+ ED+++  N  + K+ ATD+D 
Sbjct: 1191 GGSPSK---SATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAI--NTHVVKLNATDSD- 1244

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
               + + + I+ GN    F ID  SG +S+ K LD E   +Y LV+RA + GS   S   
Sbjct: 1245 --GTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYN 1302

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
               I + DVNDNAP F    + +S+ EN+PIG ++ +V A D DEG NA++TY ++  D 
Sbjct: 1303 NATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDT 1362

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +        ++P +G V T   LDRE QA Y L VTA D G P +SA A           
Sbjct: 1363 S-----KFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLND 1417

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                F   +Y + + E+   G+ ++ + A+D D   + R+ Y I  GN    F I S  G
Sbjct: 1418 NSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTG 1477

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTAS 477
            R  ITV   +D +    Y LT+SA DSG      TA V I + D N+ +P+F +   +  
Sbjct: 1478 R--ITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYG 1535

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E   IG+ V VV+ATD D G NAQ+ YS+        V      F IN   G +T  K
Sbjct: 1536 IDEGVSIGSRVAVVTATDRDEGSNAQVFYSI--------VRGDTSAFAINAMNGVLTVKK 1587

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             ++RET+       + R+    S S  T V     DV  N  V +  + + N  E     
Sbjct: 1588 EINRETVPTQSYIGSVRENSAQSTSVLT-VAADDSDVGAN-AVLRYSIISGN-DEKRFKI 1644

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             S S V  T   +    +  Y L+    +  S      +  IR     D     T     
Sbjct: 1645 NSTSGVIMTTTPLDFEEKSQYGLEVTATD--SKYTAKTNVTIRVINLNDITPAFTQQNYT 1702

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
             ++   +P  +ST +V +   D +    V   D   F I + S I +T
Sbjct: 1703 ASVRENSP--TSTSVVKVSASDRDSYSIVGGKDSDKFSIDQRSGIIST 1748



 Score =  283 bits (695), Expect = 1e-75
 Identities = 226/728 (31%), Positives = 344/728 (47%), Gaps = 86/728 (11%)

Query: 26   QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXX 85
            Q Y  SVRE ++  T+VLT+ A D D+G NA + Y+I       ++  D           
Sbjct: 1597 QSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI-------ISGND----------- 1638

Query: 86   VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
             +  F+I+  SG ++T   LD E+ ++Y + V ATD       + ++   + + +I+ ND
Sbjct: 1639 -EKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS------KYTAKTNVTIRVINLND 1691

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
              P F+++ YT SV E+ S T   V+ K+ A+D D        Y+I+GG    +FSID  
Sbjct: 1692 ITPAFTQQNYTASVREN-SPTSTSVV-KVSASDRD-------SYSIVGGKDSDKFSIDQR 1742

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            SG +S    LD E V  Y + +R  D G+P  SN T + I I D NDN+P+F +S +  S
Sbjct: 1743 SGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSS 1802

Query: 266  VSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            + EN  P  +S  ++ A DADEG NA +TY ++  D          I   SG +    +L
Sbjct: 1803 ILENSAPSSFSF-KLAATDADEGTNARITYNLSRND-------AFMIGASSGVITNVRKL 1854

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
            DRE  + Y L V A D G+P  ++                          ++E+   G  
Sbjct: 1855 DREQVSIYTLYVQAVDQGNPRLASEWVPVHIRVQDENDNAPRFVSSGNCNVSENAVVGAI 1914

Query: 385  VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            +  L A D D      + Y I    T      T  N  G+IT+AQPLD + +  Y L + 
Sbjct: 1915 IAELLAVDPDLGTGGVVSYRILTRQT----EFTIDNTTGVITLAQPLDRENKSTYDLAIQ 1970

Query: 443  ATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            A D G     + + I +T  D N++ P+  ++    SV E+ P  T V+ + A+D+D G+
Sbjct: 1971 ARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGL 2030

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
            NA++T+SL   +SNE    H   F ++  TG I+T   LDRE  + Y L +   D G PS
Sbjct: 2031 NAELTFSL---LSNE----HKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPS 2083

Query: 561  LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            LS   DV I V+D +DN P F+   Y   I E    G S+ QV A D D   +    Y +
Sbjct: 2084 LSSVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDIDGDKD--TSYAI 2141

Query: 621  DPKDREEGSFVIDPASGVIR-TNKALDRESV---------------ATHDL------KAV 658
                   G F ID  +GV+   +  +DRE                 AT+D       + +
Sbjct: 2142 KSM-TPSGGFTIDSKTGVVMVASSGVDREIADVFKLVIRAGKEHCGATNDTGGGEGGRFL 2200

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
             +   T P S   +  I++ D+ND+ P F  D   +  ++ + +   +  +RA D D G 
Sbjct: 2201 GVQQATYPDSLATVT-IQVTDVNDNAPSFSRDSYEYDFNDVTTV--NLLSVRATDLDAGV 2257

Query: 719  NAVVHYSI 726
            N VV + +
Sbjct: 2258 NGVVKFRL 2265



 Score =  260 bits (638), Expect = 9e-69
 Identities = 221/750 (29%), Positives = 344/750 (45%), Gaps = 72/750 (9%)

Query: 153  KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV 212
            ++Y  SV E+ + + +  +  + A D+DVGAN+ +RY+II GN + +F I+S SG +   
Sbjct: 1597 QSYIGSVRENSAQSTS--VLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTT 1654

Query: 213  KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
              LD+E+   Y L + A D    +++N T  +IN+   ND  P F    +  SV EN P 
Sbjct: 1655 TPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINL---NDITPAFTQQNYTASVRENSPT 1711

Query: 273  GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
              S+V+V A D D       +Y++      G      +ID RSG + T+  LDRE  + Y
Sbjct: 1712 STSVVKVSASDRD-------SYSIVG----GKDSDKFSIDQRSGIISTADVLDRELVSLY 1760

Query: 333  QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
             + V  TD G+PP S                  F    Y   + E+  P +    L ATD
Sbjct: 1761 AIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATD 1820

Query: 393  ADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-- 448
            ADE  + R+ Y ++  +    F I + +  G+IT  + LD +Q   Y L V A D G   
Sbjct: 1821 ADEGTNARITYNLSRNDA---FMIGASS--GVITNVRKLDREQVSIYTLYVQAVDQGNPR 1875

Query: 449  -RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
              S+   V I + D N+ AP F ++    +V E+A +G  +  + A D D+G    ++Y 
Sbjct: 1876 LASEWVPVHIRVQDENDNAPRFVSSG-NCNVSENAVVGAIIAELLAVDPDLGTGGVVSYR 1934

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
            + +            +F I+  TG IT  + LDRE  S Y L + ARD G P  + +  +
Sbjct: 1935 ILT---------RQTEFTIDNTTGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITI 1985

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
             ++V+D+ND+ P+        ++ E+    T V ++ A+DAD GLN  + + L   +  +
Sbjct: 1986 RVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSL-LSNEHK 2044

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
              F +D  +G I T   LDRE  A + L+    D G P  SS   V I + D +D+ P F
Sbjct: 2045 SVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRF 2104

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
            +       ISE+ P G +I ++ A D D   +    Y+IK    S  F+++++ G     
Sbjct: 2105 QPTEYNVTISESLPRGASIVQVTARDIDGDKD--TSYAIKSMTPSGGFTIDSKTG---VV 2159

Query: 748  LVTMVDLDYESPRKKYELVIRAASP--PLWND---------------------VRVEILV 784
            +V    +D E     ++LVIRA        ND                       V I V
Sbjct: 2160 MVASSGVDREI-ADVFKLVIRAGKEHCGATNDTGGGEGGRFLGVQQATYPDSLATVTIQV 2218

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILS----GNNANL 839
            TDVNDNAP        + ++ D   V     R    DA V   +++R+      G N  +
Sbjct: 2219 TDVNDNAPSFSRDSYEY-DFNDVTTVNLLSVRATDLDAGVNGVVKFRLAEQTELGGNRVV 2277

Query: 840  ILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
             +     GS +LS Q++  V    + E  V
Sbjct: 2278 KVEAYDQGSPSLSSQVSVIVQTSVSCEAMV 2307



 Score =  243 bits (595), Expect = 1e-63
 Identities = 186/607 (30%), Positives = 292/607 (48%), Gaps = 49/607 (8%)

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
           F    +  SV E +    +++ V +      V+  L Y++ D    GN     TID  +G
Sbjct: 106 FAKDSYSASVKEELQATQNVITVSS-----SVSPNLRYSIMD----GNDQGMFTIDSSTG 156

Query: 317 WVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            + T+G+  DRE++++Y+L V A D  +                      F    Y   +
Sbjct: 157 SITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNI 216

Query: 376 AEDEPPG-TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
            E+ P     +VT T  D+  +  + Y +  G  +  F + S+ G   I    PLD + +
Sbjct: 217 RENTPAAQVAIVTATDRDSGTNAAITYSLFSGENK--FMMNSKTGE--IRTVTPLDHETK 272

Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN-----APYTASVFEDAPIGTTVL 489
             Y + +SA D G  +    + INI D N   P F++        +A+V E AP+ T ++
Sbjct: 273 DSYTMRISAFD-GKHTTFVPLVINILDVNE-PPRFQDDCTRRGDCSATVLESAPLNTRIV 330

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            ++ATD D      + YS+    S E +      F I+  +G +T NK+LDRE  S Y L
Sbjct: 331 TLAATDPD---GDSLLYSVRIRDSQEKI------FTID-NSGRLTLNKMLDREAKSAYDL 380

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            V A DG + +++    ++I+V DVNDN P F   +Y   + ED  VG+ V Q+ A D D
Sbjct: 381 VVEASDGNIIAIAA---LKITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLD 437

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
           VG+N R+ Y L   D     F +D + GVIRT  A DRE+ A++ +   A DGG+P +S 
Sbjct: 438 VGINARLSYSLVSGDTSY--FTVD-SQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSG 494

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
              V I+I D+ND+ PVF S   T  + E+  IG  +  + A D D G NA + YS   G
Sbjct: 495 QATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSG 554

Query: 730 DDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYEL---VIRAASPPLWNDVRVEILVT 785
           + +++F+L+   G     +VT+   LD+E  R  Y L   V    SPPL +   + I V 
Sbjct: 555 NTNHAFTLDAVTG-----VVTVSRSLDFEQ-RSSYALGLSVTDRGSPPLTDTSHLLINVN 608

Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845
           D+NDN PV        +  K+  P G        D+     L + I+ GN+  +  ++ +
Sbjct: 609 DINDNPPVFSP-SAYQSRVKENTPAGTQVSATDRDSSTNGALVFGIIKGNDDGVFTIDGS 667

Query: 846 TGSMTLS 852
           TG ++++
Sbjct: 668 TGIISIA 674



 Score =  109 bits (262), Expect = 3e-23
 Identities = 89/315 (28%), Positives = 150/315 (47%), Gaps = 49/315 (15%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V+D NDH P+        SVRE     T V+ + A+D D G NAE+ +++       
Sbjct: 1986 RVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSL------- 2038

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+ E             + VF +D  +G + T+  LDRE+ A YT+ +   D+ +P    
Sbjct: 2039 LSNEH------------KSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNP---S 2083

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS A + +++ID++DN P+F    Y V++ E  S+     I ++ A D D   +++  Y
Sbjct: 2084 LSSVADVIIDVIDEDDNCPRFQPTEYNVTISE--SLPRGASIVQVTARDIDGDKDTS--Y 2139

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRA----------QDGGSPSR- 237
            AI        F+IDS +G V +  + +D E    ++LVIRA            GG   R 
Sbjct: 2140 AIKSMTPSGGFTIDSKTGVVMVASSGVDREIADVFKLVIRAGKEHCGATNDTGGGEGGRF 2199

Query: 238  ---------SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
                      +   + I + DVNDNAP F    ++   ++   +  +++ V+A D D GV
Sbjct: 2200 LGVQQATYPDSLATVTIQVTDVNDNAPSFSRDSYEYDFNDVTTV--NLLSVRATDLDAGV 2257

Query: 289  NAELTYTMTDKDYTG 303
            N  + + + ++   G
Sbjct: 2258 NGVVKFRLAEQTELG 2272



 Score = 55.2 bits (127), Expect = 7e-07
 Identities = 52/219 (23%), Positives = 100/219 (45%), Gaps = 31/219 (14%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD-- 68
            I+V+D +D+ P F+  +Y  ++ E    G +++  + T +DI  + +  Y I+ +T    
Sbjct: 2092 IDVIDEDDNCPRFQPTEYNVTISESLPRGASIV--QVTARDIDGDKDTSYAIKSMTPSGG 2149

Query: 69   -TLNPEDAXXXXXXXXXX--VQDVFRIDGRSGALLTRASLDRE--KVARYTVLVKATDQA 123
             T++ +              + DVF++  R+G     A+ D    +  R+  + +AT   
Sbjct: 2150 FTIDSKTGVVMVASSGVDREIADVFKLVIRAGKEHCGATNDTGGGEGGRFLGVQQATYP- 2208

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
                    S AT+ + + D NDN P FS  +Y    ++  +V     +  ++ATD D G 
Sbjct: 2209 -------DSLATVTIQVTDVNDNAPSFSRDSYEYDFNDVTTVN----LLSVRATDLDAGV 2257

Query: 184  NSAIRYAI-----IGGNTQMQFSI-----DSLSGDVSLV 212
            N  +++ +     +GGN  ++         SLS  VS++
Sbjct: 2258 NGVVKFRLAEQTELGGNRVVKVEAYDQGSPSLSSQVSVI 2296



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/44 (38%), Positives = 21/44 (47%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            C    + C   PC+N   C D   TY C C+ G TGK C  + G
Sbjct: 2584 CQFNLNECKGDPCFNNGTCQDRNGTYQCTCRPGSTGKQCELTEG 2627



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 8/84 (9%)

Query: 816  VPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873
            V A D+DV     L+Y I+SGN+     +N T+G +  +  L+        +EV+ TD  
Sbjct: 1616 VAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATD-- 1673

Query: 874  NEIKAMMQLSVRLITEEMLLNSIT 897
            ++  A   +++R+I     LN IT
Sbjct: 1674 SKYTAKTNVTIRVIN----LNDIT 1693


>SB_58036| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 6074

 Score =  386 bits (949), Expect = e-106
 Identities = 273/908 (30%), Positives = 438/908 (48%), Gaps = 75/908 (8%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H ++ VLDCND+ PVF    Y   + E  S GT +L + A D+D+G NA++ Y I     
Sbjct: 2660 HVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDVGTNAKLSYAI----- 2714

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                              V + F ID  +G L T   L+RE +  + + V ATDQ  P  
Sbjct: 2715 --------------TKGNVNETFAIDHTTGELHTTKLLNREDIPGFNLTVTATDQGVP-- 2758

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L +++ + V I+D NDN P+F+   Y V + ED        I ++ A+D D   N  +
Sbjct: 2759 -SLHTSSEVLVTILDSNDNIPRFTSPEYHVILPED--TPTGAFILQVTASDQDEDNNRML 2815

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            RY I        FS+ + SG+++L   LDYE +R +R  +  +D G+P    TT ++I +
Sbjct: 2816 RYFINDNQVMKFFSVKASSGNITLKSALDYESIRVFRFQVFVEDNGTPPHLGTTLVVIKV 2875

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVNDN P F T  +   VSE   +G  I  ++A D+D   NA+L + +T+    GNV  
Sbjct: 2876 TDVNDNDPVFSTLHYTAQVSEASNVGALIAVLKASDSDSTSNAQLNFGITE----GNVKN 2931

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXX 365
               ++   G +Y +  LD E +  Y L V+  D G P R A   A               
Sbjct: 2932 TFYVN-TEGVIYLNRSLDFEERKVYNLSVSVEDSGTPKRKAVIEANVTIYVTDENDCSPV 2990

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
            F    Y   + E+   G+ ++   A D D      Y I    + G F++      G++  
Sbjct: 2991 FSQTYYTTAIPENITVGSVILRTVALDLDS---AVYSILNTTSNGTFTVDPHT--GVLRT 3045

Query: 426  AQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            +Q LD +    Y LT++  DSG      +  A V I + D N+  PVF+   Y+ SV E+
Sbjct: 3046 SQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVYSVSVPEN 3105

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              +G  +L+++A D D G+NA+I Y L   I++       ++F +N  TG IT  + +D 
Sbjct: 3106 ITVGAHILLLNAKDKDEGVNAEIRYFLKDVIAS-------KRFSMNDTTGQITIKQAVDY 3158

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E  S Y   V A DGG   L+ ++ V I+++DVNDN P F    Y   ++E+  +GT+V+
Sbjct: 3159 EERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVT 3218

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            Q+ A+D D  LNG + + +  +   +G F+ID  +GV+ TNK+LD E V  + L   A D
Sbjct: 3219 QMTASDLDSSLNGNVLFSI-LEGNSDGKFLIDQNTGVVTTNKSLDYEDVTKYTLVIQATD 3277

Query: 662  GGTPPQSSTV--IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GP 718
             G PP +S+   ++H+ + +IND+ PVF     +  I EN+ +G  I  ++A D D    
Sbjct: 3278 CGDPPLNSSQPGMLHVSVVNINDNSPVFLQKMYSASIDENTAVGHVILRVQATDRDHVNS 3337

Query: 719  NAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----- 771
            +++V Y +   D      F++  + G    EL+ +  LDYES  K Y+  + A       
Sbjct: 3338 SSIVIYYLDQSDTEAMRYFTINNQTG----ELILVSSLDYES-TKGYQFTVFAGDNIAQF 3392

Query: 772  ---PPLWNDVRV-----EILVTDVNDNAP-VMKDFQ--IIFNNYKDCFPVGPFGRVPAYD 820
                 + +  RV     +I + D+NDN P  ++ +    I    ++   +       A D
Sbjct: 3393 RKRRDIGDQARVAAVLIDISILDINDNRPKFLRPYNKIEITEGTREGTMILTLQATDA-D 3451

Query: 821  ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880
            + +  KL Y IL+  +     ++  TG +  S +L+       T+ ++V D  + +    
Sbjct: 3452 SGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAA 3511

Query: 881  QLSVRLIT 888
            Q ++  IT
Sbjct: 3512 QPAIVSIT 3519



 Score =  385 bits (948), Expect = e-106
 Identities = 276/923 (29%), Positives = 442/923 (47%), Gaps = 72/923 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++LD ND+ P F     +  + EG    T +LTL+ATD D G NA++ Y+I   T++  
Sbjct: 3848 ISILDINDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGVNAKLVYSILNTTSN-- 3905

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F +D  +G L T   LDRE V  YT+ +   D   P+ +  
Sbjct: 3906 -----------------GTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLND- 3947

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +  AT+ + ++D+NDN P F ++ Y+VS+ E+I+V  +  I  + A D D G N+ IRY 
Sbjct: 3948 AQPATVSITVLDENDNVPVFDQEVYSVSIPENITVGAH--ILLLNARDKDEGVNAEIRYF 4005

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +       +FS++  +G +++ + +DYE+  SY   + A DGG    + ++ + I I DV
Sbjct: 4006 LKDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDV 4065

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  + +   + ENV IG ++ +V A D D  +N ++ +++ +    GN D    
Sbjct: 4066 NDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILE----GNSDGKFV 4121

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMP 368
            ID  +G V T+  LD E   +Y L++ ATD GDPP   S                  F  
Sbjct: 4122 IDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ 4181

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITV 425
              Y   + E+   G  ++ + ATD D  NR   + Y +   +T      T  N  G + +
Sbjct: 4182 KIYSASIDENTTVGHVILRVQATDRDHVNRSSIVIYSLDQSDTEAMRYFTINNRTGELIL 4241

Query: 426  AQPLDFKQERRYVLTVSATDS----------GGRSDTA--MVQINITDANNYAPVFENAP 473
               LD++  +RY  TV A D+          G ++  A  ++ I+I D N+  P F  + 
Sbjct: 4242 VSSLDYESTKRYEFTVFAGDNTAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSY 4301

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
                + E     T +L + ATD+D G+NA++ YS+ +  SN         F ++P TG +
Sbjct: 4302 NKIEITEGTRESTMILTLQATDADSGMNAKLVYSILNTTSNGT-------FTVDPHTGVL 4354

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             T++ LDRET++ Y LT+T  D G P L  +    V I+V+D NDN PVF Q++Y+ +I 
Sbjct: 4355 RTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVYSVSIP 4414

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESV 650
            E+  VG  +  + A D D G+N  I Y L  KD      F ++  +G I   +A+D E  
Sbjct: 4415 ENITVGAHILLLNAKDKDEGVNAEIRYFL--KDLIASKRFSMNDTTGQITIKQAVDYEER 4472

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
            +++  +  A DGG    + +  V I I D+ND+ P F        + EN  IGTT+ ++ 
Sbjct: 4473 SSYSFEVFASDGGETRLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVT 4532

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA- 769
            A D D   N  V +SI  G+    F ++   G     + T   LDYE    KY LVI+A 
Sbjct: 4533 ASDLDSSLNGKVLFSILEGNSDGKFVIDQNTG----VVTTNKSLDYEDV-TKYTLVIQAT 4587

Query: 770  --ASPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT 824
                PPL +     + + V ++NDN+PV    +I   +  +   VG    RV A D D  
Sbjct: 4588 DCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ-KIYSASIDENTTVGHVILRVQATDRDHV 4646

Query: 825  DKLQYRILSGNNAN-----LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879
            ++    I S + ++        +N  TG + L   L+    K     V   D + + +  
Sbjct: 4647 NRSSIVIYSLDQSDTEAMRYFAINNQTGELILVSSLDYESTKRYEFTVFAGDNIAQFRKR 4706

Query: 880  MQLSVRLITEEMLLNSITVRLND 902
              +  +     +L++   + +ND
Sbjct: 4707 RDIRDQARVAAVLIDISILDIND 4729



 Score =  383 bits (942), Expect = e-105
 Identities = 276/899 (30%), Positives = 441/899 (49%), Gaps = 78/899 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND+ PVF+ + Y  SV E  + G  +L L A D+D G NAE+ Y ++ V A   
Sbjct: 3081 ITVLDENDNVPVFDQEVYSVSVPENITVGAHILLLNAKDKDEGVNAEIRYFLKDVIASKR 3140

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ++  +G +  + ++D E+ + Y+  V A+D       RL
Sbjct: 3141 -------------------FSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEA---RL 3178

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + ++++ + IID NDN P F    Y V + E++++     + ++ A+D D   N  + ++
Sbjct: 3179 TGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI--GTTVTQMTASDLDSSLNGNVLFS 3236

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIR 248
            I+ GN+  +F ID  +G V+  K+LDYE V  Y LVI+A D G P  + S    L +++ 
Sbjct: 3237 ILEGNSDGKFLIDQNTGVVTTNKSLDYEDVTKYTLVIQATDCGDPPLNSSQPGMLHVSVV 3296

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            ++NDN+P F   ++  S+ EN  +G+ I+RVQA D D   ++ +     D+  T  +   
Sbjct: 3297 NINDNSPVFLQKMYSASIDENTAVGHVILRVQATDRDHVNSSSIVIYYLDQSDTEAMRY- 3355

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG----------GDPPRSATATXXXXXXX 358
             TI+ ++G +     LD E+   YQ  V A D           GD  R A          
Sbjct: 3356 FTINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAVLIDISILD 3415

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                   F+    ++E+ E    GT ++TL ATDAD   + +L Y I    + G F++  
Sbjct: 3416 INDNRPKFLRPYNKIEITEGTREGTMILTLQATDADSGMNAKLVYSILNTTSNGTFTVDP 3475

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENA 472
                G++  +Q LD +    Y LT++  DSG      +  A+V I + D N+  PVF+  
Sbjct: 3476 HT--GVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPAIVSITVLDENDNIPVFDQE 3533

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y+ SV E+  +G  +L+++A D D G+NA+I Y L   I +       ++F IN  TG 
Sbjct: 3534 VYSVSVPENITVGGHILLLNARDKDEGVNAEIRYFLKDAIVS-------KKFSINDTTGQ 3586

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            IT  + +D E  S Y   V A DGG   L+ ++ V I+++DVNDN P F    Y   ++E
Sbjct: 3587 ITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVE 3646

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            +  +GT V+QV A+D D  LNG++ + +      +G FVID  +GV+ TNK+LD E V  
Sbjct: 3647 NVAIGTPVTQVTASDLDSSLNGKVLFSI-LGGNSDGKFVIDQNTGVVTTNKSLDYEDVTE 3705

Query: 653  HDLKAVAIDGGTPPQSSTV--IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
            + L   A D G PP +S+   ++H+ + +IND+ PVF     +  I EN+ +G  I  ++
Sbjct: 3706 YTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVQ 3765

Query: 711  AHDPDE-GPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            A D D    +++V YS+   D      F++  R G    EL+ +  LDYES  K Y+  +
Sbjct: 3766 ATDRDHVNSSSIVIYSLDQSDTEAMRYFTINNRTG----ELILVSSLDYES-TKGYQFTV 3820

Query: 768  RAAS--------PPLWNDVRV-----EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814
             A            + +  RV     +I + D+NDN P            +         
Sbjct: 3821 FAGDNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSYNKIEITEGTRESTMIL 3880

Query: 815  RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             + A DAD  V  KL Y IL+  +     ++  TG +  S +L+       T+ ++V D
Sbjct: 3881 TLQATDADSGVNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHD 3939



 Score =  382 bits (941), Expect = e-105
 Identities = 276/923 (29%), Positives = 438/923 (47%), Gaps = 72/923 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++LD ND+ P F     +  + EG   GT +LTL+ATD D G NA++ Y+I   T++  
Sbjct: 3411 ISILDINDNRPKFLRPYNKIEITEGTREGTMILTLQATDADSGMNAKLVYSILNTTSN-- 3468

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F +D  +G L T   LDRE V  YT+ +   D   P+ +  
Sbjct: 3469 -----------------GTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNA- 3510

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +  A + + ++D+NDN P F ++ Y+VSV E+I+V  +  I  + A D D G N+ IRY 
Sbjct: 3511 AQPAIVSITVLDENDNIPVFDQEVYSVSVPENITVGGH--ILLLNARDKDEGVNAEIRYF 3568

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +       +FSI+  +G +++ + +DYE+  SY   + A DGG    + ++ + I I DV
Sbjct: 3569 LKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDV 3628

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  + +   + ENV IG  + +V A D D  +N ++ +++      GN D    
Sbjct: 3629 NDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSILG----GNSDGKFV 3684

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMP 368
            ID  +G V T+  LD E   +Y L++ ATD GDPP   S                  F  
Sbjct: 3685 IDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ 3744

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITV 425
              Y   + E+   G  ++ + ATD D  N    + Y +   +T      T  N  G + +
Sbjct: 3745 KMYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRYFTINNRTGELIL 3804

Query: 426  AQPLDFKQERRYVLTVSATDS----------GGRSDTA--MVQINITDANNYAPVFENAP 473
               LD++  + Y  TV A D+          G ++  A  ++ I+I D N+  P F  + 
Sbjct: 3805 VSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSY 3864

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
                + E     T +L + ATD+D G+NA++ YS+ +  SN         F ++P TG +
Sbjct: 3865 NKIEITEGTRESTMILTLQATDADSGVNAKLVYSILNTTSNGT-------FTVDPHTGVL 3917

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVFKQQLYTANIM 591
             T++ LDRET++ Y LT+T  D G P L+D     V I+V+D NDN PVF Q++Y+ +I 
Sbjct: 3918 RTSQRLDRETVTEYTLTITVHDSGDPMLNDAQPATVSITVLDENDNVPVFDQEVYSVSIP 3977

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESV 650
            E+  VG  +  + A D D G+N  I Y L  KD      F ++  +G I   +A+D E  
Sbjct: 3978 ENITVGAHILLLNARDKDEGVNAEIRYFL--KDAIVSKRFSMNDTTGQITIKQAVDYEER 4035

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
            +++  +  A DGG    + +  V I I D+ND+ P F        + EN  IGTT+ ++ 
Sbjct: 4036 SSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVT 4095

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA- 769
            A D D   N  V +SI  G+    F ++   G     + T   LDYE    +Y LVI+A 
Sbjct: 4096 ASDLDSSLNGKVLFSILEGNSDGKFVIDQNTG----VVTTNKSLDYEDV-TEYTLVIQAT 4150

Query: 770  --ASPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT 824
                PPL +     + + V ++NDN+PV    +I   +  +   VG    RV A D D  
Sbjct: 4151 DCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ-KIYSASIDENTTVGHVILRVQATDRDHV 4209

Query: 825  DKLQYRILSGNNAN-----LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879
            ++    I S + ++        +N  TG + L   L+    K     V   D   + +  
Sbjct: 4210 NRSSIVIYSLDQSDTEAMRYFTINNRTGELILVSSLDYESTKRYEFTVFAGDNTAQFRKR 4269

Query: 880  MQLSVRLITEEMLLNSITVRLND 902
              +  +     +L++   + +ND
Sbjct: 4270 RDIGDQARVAAVLIDISILDIND 4292



 Score =  379 bits (932), Expect = e-104
 Identities = 280/920 (30%), Positives = 439/920 (47%), Gaps = 70/920 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND+ P+F   +Y   + E  +SGT VLTL A D+D G N +V Y I  VT+   
Sbjct: 2558 VKVLDANDNPPIFNQSEYYVEMYENVTSGTQVLTLFAHDRDEGINGQVFYYI--VTSS-- 2613

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V+ VF  +  +G +   A LDRE V +Y +LV A D  SP     
Sbjct: 2614 ---------------VKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPR--- 2655

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +++A + V ++D NDN P F+   YT+ + E  S+     I ++ A D DVG N+ + YA
Sbjct: 2656 TASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTR--ILRVSANDRDVGTNAKLSYA 2713

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN    F+ID  +G++   K L+ E +  + L + A D G PS   ++++L+ I D 
Sbjct: 2714 ITKGNVNETFAIDHTTGELHTTKLLNREDIPGFNLTVTATDQGVPSLHTSSEVLVTILDS 2773

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN PRF +  +   + E+ P G  I++V A D DE  N  L Y + D      V    +
Sbjct: 2774 NDNIPRFTSPEYHVILPEDTPTGAFILQVTASDQDEDNNRMLRYFIND----NQVMKFFS 2829

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +   SG +     LD E+   ++  V   D G PP   T                F    
Sbjct: 2830 VKASSGNITLKSALDYESIRVFRFQVFVEDNGTPPHLGTTLVVIKVTDVNDNDPVFSTLH 2889

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y  +++E    G  +  L A+D+D  +  +L++ IT GN +  F +   N  G+I + + 
Sbjct: 2890 YTAQVSEASNVGALIAVLKASDSDSTSNAQLNFGITEGNVKNTFYV---NTEGVIYLNRS 2946

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQIN----ITDANNYAPVFENAPYTASVFEDAPI 484
            LDF++ + Y L+VS  DSG     A+++ N    +TD N+ +PVF    YT ++ E+  +
Sbjct: 2947 LDFEERKVYNLSVSVEDSGTPKRKAVIEANVTIYVTDENDCSPVFSQTYYTTAIPENITV 3006

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G+ +L   A D D  +     YS+ +  SN         F ++P TG + T++ LDRET+
Sbjct: 3007 GSVILRTVALDLDSAV-----YSILNTTSNGT-------FTVDPHTGVLRTSQRLDRETV 3054

Query: 545  SGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            + Y LT+T  D G P L  +    V I+V+D NDN PVF Q++Y+ ++ E+  VG  +  
Sbjct: 3055 TEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVYSVSVPENITVGAHILL 3114

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            + A D D G+N  I Y L      +  F ++  +G I   +A+D E  +++  +  A DG
Sbjct: 3115 LNAKDKDEGVNAEIRYFLKDVIASK-RFSMNDTTGQITIKQAVDYEERSSYSFEVFASDG 3173

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G    + +  V I I D+ND+ P F        + EN  IGTT+ ++ A D D   N  V
Sbjct: 3174 GEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQMTASDLDSSLNGNV 3233

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV- 778
             +SI  G+    F ++   G     + T   LDYE    KY LVI+A     PPL +   
Sbjct: 3234 LFSILEGNSDGKFLIDQNTG----VVTTNKSLDYEDV-TKYTLVIQATDCGDPPLNSSQP 3288

Query: 779  -RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK----LQYRIL 832
              + + V ++NDN+PV    ++   +  +   VG    RV A D D  +     + Y   
Sbjct: 3289 GMLHVSVVNINDNSPVFLQ-KMYSASIDENTAVGHVILRVQATDRDHVNSSSIVIYYLDQ 3347

Query: 833  SGNNA-NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
            S   A     +N  TG + L   L+    K     V   D + + +    +  +     +
Sbjct: 3348 SDTEAMRYFTINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAV 3407

Query: 892  LLNSITVRLNDMTAEQFLSP 911
            L++   + +ND    +FL P
Sbjct: 3408 LIDISILDIND-NRPKFLRP 3426



 Score =  372 bits (916), Expect = e-102
 Identities = 269/904 (29%), Positives = 438/904 (48%), Gaps = 72/904 (7%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60
            S P  +H  ++V++ ND+SPVF  + Y AS+ E  + G  +L ++ATD+D + +++ V Y
Sbjct: 4597 SQPGMLH--VSVVNINDNSPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNRSSIVIY 4654

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
            +++    + +                   F I+ ++G L+  +SLD E   RY   V A 
Sbjct: 4655 SLDQSDTEAMR-----------------YFAINNQTGELILVSSLDYESTKRYEFTVFAG 4697

Query: 121  DQASPVSDRLS-------STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
            D  +    R         +   I ++I+D NDN P+F +    + + E     ++ +I  
Sbjct: 4698 DNIAQFRKRRDIRDQARVAAVLIDISILDINDNRPKFLQSYNKIEITE--GTRESTMILT 4755

Query: 174  IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            ++ATDAD G N+ + Y+I+   +   F++D  +G +   + LD E V  Y L I   D G
Sbjct: 4756 LQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 4815

Query: 234  SPSRSNTTQLLINIR--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
             P  +     +++I   D NDN P F   ++  S+ EN+ +G  I+ + A D DEGVNAE
Sbjct: 4816 DPMLNAAQPAIVSITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAE 4875

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            + Y + D      V    +++  +G +     +D E ++ Y   V A+DGG+   + +++
Sbjct: 4876 IRYFLKD----AIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSS 4931

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409
                          F+P +Y V+L E+   GT V  LTA+D D   + ++ + I  GN+ 
Sbjct: 4932 VRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQLTASDLDSSLNGKVLFSILEGNSD 4991

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465
            G+FSI  QN  G++T  + LD++    Y L + ATD G      S   M+ +++ + N+ 
Sbjct: 4992 GKFSI-DQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 5049

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524
            +PVF    Y+AS+ E+  +G  +L V ATD D V  ++ + YSL  +   EA+ +    F
Sbjct: 5050 SPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSL-DQSDTEAMRY----F 5104

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTA----------RDGGVPSLSDTTDVEISVVDV 574
             IN QTG +     LD E+  GY  TV A          RD G  +      ++IS++D+
Sbjct: 5105 AINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKNRDIGDQARVAAVLIDISILDI 5164

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            NDN P F Q      I E     T +  + ATDAD G+N ++ Y +       G+F +DP
Sbjct: 5165 NDNRPKFPQPYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI-LNTTSNGTFTVDP 5223

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCL 692
             +GV+RT++ LDRE+V  + L     D G P    + T  V I + D ND+ PVF+ +  
Sbjct: 5224 HTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQTATVSITVLDENDNVPVFDQEVY 5283

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
            +  I EN  +G  I  + A D DEG NA + Y +K    S  FS+    G    ++    
Sbjct: 5284 SVSIPENITVGAHILLLNARDKDEGVNAEILYFLKDVIASKRFSMNDTTG----QITIKQ 5339

Query: 753  DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
             +DYE  R  Y   + A+      L     V I + DVNDN P     +      ++   
Sbjct: 5340 AVDYEE-RSSYSFEVFASDSGEARLTGSSSVRIPIIDVNDNRPYFLPTRYYVQLVENVAI 5398

Query: 810  VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                 +V A D D  +  K+ + IL GN+    ++++ TG +T +  L+       T+ +
Sbjct: 5399 GTTVTQVYASDLDSSLNGKVLFSILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVI 5458

Query: 868  SVTD 871
              TD
Sbjct: 5459 QATD 5462



 Score =  370 bits (911), Expect = e-102
 Identities = 270/904 (29%), Positives = 436/904 (48%), Gaps = 72/904 (7%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60
            S P  +H  ++V++ ND+SPVF  + Y AS+ E  + G  +L ++ATD+D +  ++ V Y
Sbjct: 3286 SQPGMLH--VSVVNINDNSPVFLQKMYSASIDENTAVGHVILRVQATDRDHVNSSSIVIY 3343

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
             ++   +DT                    F I+ ++G L+  +SLD E    Y   V A 
Sbjct: 3344 YLD--QSDT---------------EAMRYFTINNQTGELILVSSLDYESTKGYQFTVFAG 3386

Query: 121  DQAS------PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
            D  +       + D+    A  I ++I+D NDN P+F      + + E     +  +I  
Sbjct: 3387 DNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLRPYNKIEITE--GTREGTMILT 3444

Query: 174  IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            ++ATDAD G N+ + Y+I+   +   F++D  +G +   + LD E V  Y L I   D G
Sbjct: 3445 LQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 3504

Query: 234  SPSRSNTTQLLINIR--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
             P  +     +++I   D NDN P F   ++  SV EN+ +G  I+ + A D DEGVNAE
Sbjct: 3505 DPMLNAAQPAIVSITVLDENDNIPVFDQEVYSVSVPENITVGGHILLLNARDKDEGVNAE 3564

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            + Y + D      V    +I+  +G +     +D E ++ Y   V A+DGG+   + +++
Sbjct: 3565 IRYFLKD----AIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSS 3620

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409
                          F+P +Y V+L E+   GTPV  +TA+D D   + ++ + I GGN+ 
Sbjct: 3621 VRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSILGGNSD 3680

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465
            G+F +  QN  G++T  + LD++    Y L + ATD G      S   M+ +++ + N+ 
Sbjct: 3681 GKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 3738

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524
            +PVF    Y+AS+ E+  +G  +L V ATD D V  ++ + YSL  +   EA+ +    F
Sbjct: 3739 SPVFSQKMYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSL-DQSDTEAMRY----F 3793

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTA----------RDGGVPSLSDTTDVEISVVDV 574
             IN +TG +     LD E+  GY  TV A          RD G  +      ++IS++D+
Sbjct: 3794 TINNRTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKRRDIGDQARVAAVLIDISILDI 3853

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            NDN P F Q      I E     T +  + ATDAD G+N ++ Y +       G+F +DP
Sbjct: 3854 NDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGVNAKLVYSI-LNTTSNGTFTVDP 3912

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCL 692
             +GV+RT++ LDRE+V  + L     D G P    +    V I + D ND+ PVF+ +  
Sbjct: 3913 HTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNDAQPATVSITVLDENDNVPVFDQEVY 3972

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
            +  I EN  +G  I  + A D DEG NA + Y +K    S  FS+    G    ++    
Sbjct: 3973 SVSIPENITVGAHILLLNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTG----QITIKQ 4028

Query: 753  DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
             +DYE  R  Y   + A+      L     V I + DVNDN P     +      ++   
Sbjct: 4029 AVDYEE-RSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI 4087

Query: 810  VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                 +V A D D  +  K+ + IL GN+    ++++ TG +T +  L+       T+ +
Sbjct: 4088 GTTVTQVTASDLDSSLNGKVLFSILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVI 4147

Query: 868  SVTD 871
              TD
Sbjct: 4148 QATD 4151



 Score =  366 bits (901), Expect = e-100
 Identities = 247/807 (30%), Positives = 394/807 (48%), Gaps = 63/807 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++LD ND+ P F     +  + EG    T +LTL+ATD D G NA++ Y+I   T++  
Sbjct: 4722 ISILDINDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSILNTTSN-- 4779

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F +D  +G L T   LDRE V  YT+ +   D   P+ +  
Sbjct: 4780 -----------------GTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNA- 4821

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +  A + + ++D+NDN P F ++ Y+VS+ E+I+V  +  I  + A D D G N+ IRY 
Sbjct: 4822 AQPAIVSITVLDENDNVPVFDQEVYSVSIPENITVGAH--ILLLNARDKDEGVNAEIRYF 4879

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +       +FS++  +G +++ + +DYE+  SY   + A DGG    + ++ + I I DV
Sbjct: 4880 LKDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDV 4939

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  + +   + ENV IG ++ ++ A D D  +N ++ +++ +    GN D   +
Sbjct: 4940 NDNRPYFLPTRYYVQLVENVAIGTTVTQLTASDLDSSLNGKVLFSILE----GNSDGKFS 4995

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMP 368
            ID  +G V T+  LD E   +Y L++ ATD GDPP   S                  F  
Sbjct: 4996 IDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ 5055

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITV 425
              Y   + E+   G  ++ + ATD D  N    + Y +   +T         N  G + +
Sbjct: 5056 KIYSASIDENTTVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRYFAINNQTGELIL 5115

Query: 426  AQPLDFKQERRYVLTVSATDS----------GGRSDTA--MVQINITDANNYAPVFENAP 473
               LD++  + Y  TV A D+          G ++  A  ++ I+I D N+  P F    
Sbjct: 5116 VSSLDYESTKGYQFTVFAGDNIAQFRKNRDIGDQARVAAVLIDISILDINDNRPKFPQPY 5175

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
                + E     T +L + ATD+D G+NA++ YS+ +  SN         F ++P TG +
Sbjct: 5176 NKIEITEGTRESTMILTLQATDADSGMNAKLVYSILNTTSNGT-------FTVDPHTGVL 5228

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             T++ LDRET++ Y LT+T  D G P L  + T  V I+V+D NDN PVF Q++Y+ +I 
Sbjct: 5229 RTSQRLDRETVTEYTLTITVHDSGDPMLNAAQTATVSITVLDENDNVPVFDQEVYSVSIP 5288

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
            E+  VG  +  + A D D G+N  I Y L      +  F ++  +G I   +A+D E  +
Sbjct: 5289 ENITVGAHILLLNARDKDEGVNAEILYFLKDVIASK-RFSMNDTTGQITIKQAVDYEERS 5347

Query: 652  THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
            ++  +  A D G    + +  V I I D+ND+ P F        + EN  IGTT+ ++ A
Sbjct: 5348 SYSFEVFASDSGEARLTGSSSVRIPIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVYA 5407

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769
             D D   N  V +SI  G+    F ++   G     + T   LDYE    +Y LVI+A  
Sbjct: 5408 SDLDSSLNGKVLFSILEGNSDGKFVIDQNTG----VVTTNKSLDYEDV-TEYTLVIQATD 5462

Query: 770  -ASPPLWNDV--RVEILVTDVNDNAPV 793
               PPL +     + + V ++NDN PV
Sbjct: 5463 CGDPPLNSSQPGMLHVSVVNINDNIPV 5489



 Score =  363 bits (894), Expect = e-100
 Identities = 266/904 (29%), Positives = 437/904 (48%), Gaps = 72/904 (7%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60
            S P  +H  ++V++ ND+SPVF  + Y AS+ E  + G  +L ++ATD+D +  ++ V Y
Sbjct: 3723 SQPGMLH--VSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVQATDRDHVNSSSIVIY 3780

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
            +++   +DT                    F I+ R+G L+  +SLD E    Y   V A 
Sbjct: 3781 SLD--QSDT---------------EAMRYFTINNRTGELILVSSLDYESTKGYQFTVFAG 3823

Query: 121  DQAS------PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
            D  +       + D+    A  I ++I+D NDN P+F +    + + E     ++ +I  
Sbjct: 3824 DNIAQFRKRRDIGDQARVAAVLIDISILDINDNRPKFLQSYNKIEITE--GTRESTMILT 3881

Query: 174  IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            ++ATDAD G N+ + Y+I+   +   F++D  +G +   + LD E V  Y L I   D G
Sbjct: 3882 LQATDADSGVNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 3941

Query: 234  SP--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
             P  + +    + I + D NDN P F   ++  S+ EN+ +G  I+ + A D DEGVNAE
Sbjct: 3942 DPMLNDAQPATVSITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAE 4001

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            + Y + D      V    +++  +G +     +D E ++ Y   V A+DGG+   + +++
Sbjct: 4002 IRYFLKD----AIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSS 4057

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409
                          F+P +Y V+L E+   GT V  +TA+D D   + ++ + I  GN+ 
Sbjct: 4058 VRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILEGNSD 4117

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465
            G+F +  QN  G++T  + LD++    Y L + ATD G      S   M+ +++ + N+ 
Sbjct: 4118 GKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 4175

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524
            +PVF    Y+AS+ E+  +G  +L V ATD D V  ++ + YSL  +   EA+ +    F
Sbjct: 4176 SPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNRSSIVIYSL-DQSDTEAMRY----F 4230

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTA----------RDGGVPSLSDTTDVEISVVDV 574
             IN +TG +     LD E+   Y  TV A          RD G  +      ++IS++D+
Sbjct: 4231 TINNRTGELILVSSLDYESTKRYEFTVFAGDNTAQFRKRRDIGDQARVAAVLIDISILDI 4290

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            NDN P F Q      I E     T +  + ATDAD G+N ++ Y +       G+F +DP
Sbjct: 4291 NDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI-LNTTSNGTFTVDP 4349

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFESDCL 692
             +GV+RT++ LDRE+V  + L     D G P  ++     V I + D ND+ PVF+ +  
Sbjct: 4350 HTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQEVY 4409

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
            +  I EN  +G  I  + A D DEG NA + Y +K    S  FS+    G    ++    
Sbjct: 4410 SVSIPENITVGAHILLLNAKDKDEGVNAEIRYFLKDLIASKRFSMNDTTG----QITIKQ 4465

Query: 753  DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
             +DYE  R  Y   + A+      L     V I + DVNDN P     +      ++   
Sbjct: 4466 AVDYEE-RSSYSFEVFASDGGETRLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI 4524

Query: 810  VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                 +V A D D  +  K+ + IL GN+    ++++ TG +T +  L+       T+ +
Sbjct: 4525 GTTVTQVTASDLDSSLNGKVLFSILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTKYTLVI 4584

Query: 868  SVTD 871
              TD
Sbjct: 4585 QATD 4588



 Score =  359 bits (883), Expect = 2e-98
 Identities = 255/800 (31%), Positives = 384/800 (48%), Gaps = 46/800 (5%)

Query: 87   QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST--ATIHVNIIDDN 144
            +DV R+    G ++   SLD E  A Y + + A D  SP   RL+S   AT+ V ++D N
Sbjct: 2509 EDV-RVGSTLGFIIVNDSLDFETTASYNLTIVAFDSGSP---RLASLVPATVFVKVLDAN 2564

Query: 145  DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
            DN P F++  Y V + E+  VT    +  + A D D G N  + Y I+  + +  F+ +S
Sbjct: 2565 DNPPIFNQSEYYVEMYEN--VTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNS 2622

Query: 205  LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
             +G VSL   LD E V  Y +++ AQDGGSP R+ +  + + + D NDN P F T  +  
Sbjct: 2623 TTGVVSLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTL 2682

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
             +SE   IG  I+RV A D D G NA+L+Y +T     GNV+    ID  +G ++T+  L
Sbjct: 2683 QLSEATSIGTRILRVSANDRDVGTNAKLSYAIT----KGNVNETFAIDHTTGELHTTKLL 2738

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
            +RE    + L VTATD G P    ++               F   +Y V L ED P G  
Sbjct: 2739 NREDIPGFNLTVTATDQGVPSLHTSSEVLVTILDSNDNIPRFTSPEYHVILPEDTPTGAF 2798

Query: 385  VVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            ++ +TA+D DEDN   L Y I        FS+ + +G   IT+   LD++  R +   V 
Sbjct: 2799 ILQVTASDQDEDNNRMLRYFINDNQVMKFFSVKASSGN--ITLKSALDYESIRVFRFQVF 2856

Query: 443  ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
              D+G      T +V I +TD N+  PVF    YTA V E + +G  + V+ A+DSD   
Sbjct: 2857 VEDNGTPPHLGTTLVVIKVTDVNDNDPVFSTLHYTAQVSEASNVGALIAVLKASDSDSTS 2916

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
            NAQ+ + ++         +    F +N + G I  N+ LD E    Y L+V+  D G P 
Sbjct: 2917 NAQLNFGITE-------GNVKNTFYVNTE-GVIYLNRSLDFEERKVYNLSVSVEDSGTPK 2968

Query: 561  LSDT--TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
                   +V I V D ND  PVF Q  YT  I E+  VG+ + +  A D D  +   ++ 
Sbjct: 2969 RKAVIEANVTIYVTDENDCSPVFSQTYYTTAIPENITVGSVILRTVALDLDSAVYSILN- 3027

Query: 619  ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST--VIVHIK 676
                     G+F +DP +GV+RT++ LDRE+V  + L     D G P  ++     V I 
Sbjct: 3028 -----TTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSIT 3082

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
            + D ND+ PVF+ +  +  + EN  +G  I  + A D DEG NA + Y +K    S  FS
Sbjct: 3083 VLDENDNVPVFDQEVYSVSVPENITVGAHILLLNAKDKDEGVNAEIRYFLKDVIASKRFS 3142

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPV 793
            +    G    ++     +DYE  R  Y   + A+      L     V I + DVNDN P 
Sbjct: 3143 MNDTTG----QITIKQAVDYEE-RSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPY 3197

Query: 794  MKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL 851
                +      ++        ++ A D D  +   + + IL GN+    L+++ TG +T 
Sbjct: 3198 FLPTRYYVQLVENVAIGTTVTQMTASDLDSSLNGNVLFSILEGNSDGKFLIDQNTGVVTT 3257

Query: 852  SPQLNTNVPKLATMEVSVTD 871
            +  L+       T+ +  TD
Sbjct: 3258 NKSLDYEDVTKYTLVIQATD 3277



 Score =  359 bits (882), Expect = 2e-98
 Identities = 281/918 (30%), Positives = 448/918 (48%), Gaps = 83/918 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I ++D ND+ P F   +Y   + E  + GTTV  + A+D D   N +V ++I    +D 
Sbjct: 4059 RITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILEGNSD- 4117

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID  +G + T  SLD E V  YT++++ATD   P  + 
Sbjct: 4118 ------------------GKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNS 4159

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIR 188
             S    +HV++++ NDN P FS+K Y+ S+DE+ +V    VI +++ATD D V  +S + 
Sbjct: 4160 -SQPGMLHVSVVNINDNSPVFSQKIYSASIDENTTV--GHVILRVQATDRDHVNRSSIVI 4216

Query: 189  YAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG----------GSPS 236
            Y++   +T+    F+I++ +G++ LV +LDYE  + Y   + A D           G  +
Sbjct: 4217 YSLDQSDTEAMRYFTINNRTGELILVSSLDYESTKRYEFTVFAGDNTAQFRKRRDIGDQA 4276

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            R     + I+I D+NDN P+F  S  +  ++E       I+ +QA DAD G+NA+L Y++
Sbjct: 4277 RVAAVLIDISILDINDNRPKFLQSYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI 4336

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXX 354
             +    G      T+DP +G + TS +LDRET  +Y L +T  D GDP  +A   AT   
Sbjct: 4337 LNTTSNGT----FTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSI 4392

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRF 412
                       F    Y V + E+   G  ++ L A D DE  +  + Y +       RF
Sbjct: 4393 TVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNAKDKDEGVNAEIRYFLKDLIASKRF 4452

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470
            S+    G+  IT+ Q +D+++   Y   V A+D G    + ++ V+I I D N+  P F 
Sbjct: 4453 SMNDTTGQ--ITIKQAVDYEERSSYSFEVFASDGGETRLTGSSSVRITIIDVNDNRPYFL 4510

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               Y   + E+  IGTTV  V+A+D D  +N ++ +S+          + D +FVI+  T
Sbjct: 4511 PTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSILE-------GNSDGKFVIDQNT 4563

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588
            G +TTNK LD E ++ Y L + A D G P L+ +    + +SVV++NDN PVF Q++Y+A
Sbjct: 4564 GVVTTNKSLDYEDVTKYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKIYSA 4623

Query: 589  NIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALD 646
            +I E+  VG  + +V ATD D V  +  + Y LD  D E    F I+  +G +    +LD
Sbjct: 4624 SIDENTTVGHVILRVQATDRDHVNRSSIVIYSLDQSDTEAMRYFAINNQTGELILVSSLD 4683

Query: 647  RESVATHDLKAVAIDG----------GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
             ES   ++    A D               + + V++ I I DIND+ P F        I
Sbjct: 4684 YESTKRYEFTVFAGDNIAQFRKRRDIRDQARVAAVLIDISILDINDNRPKFLQSYNKIEI 4743

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
            +E +   T I  ++A D D G NA + YSI     + +F+++   G     L T   LD 
Sbjct: 4744 TEGTRESTMILTLQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGV----LRTSQRLDR 4799

Query: 757  ESPRKKYELVIRA--ASPPLWNDVR---VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
            E+  + Y L I    +  P+ N  +   V I V D NDN PV  D ++   +  +   VG
Sbjct: 4800 ETVTE-YTLTITVHDSGDPMLNAAQPAIVSITVLDENDNVPVF-DQEVYSVSIPENITVG 4857

Query: 812  P-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
                 + A D D  V  +++Y +     +    +N+TTG +T+   ++       + EV 
Sbjct: 4858 AHILLLNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVF 4917

Query: 869  VTDGVNEIKAMMQLSVRL 886
             +DG  E +     SVR+
Sbjct: 4918 ASDG-GEARLTGSSSVRI 4934



 Score =  354 bits (871), Expect = 5e-97
 Identities = 263/863 (30%), Positives = 425/863 (49%), Gaps = 67/863 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +++VLD ND+ P F   QY+ +V E    G+ ++TL + D D   N  V +  ++++ D 
Sbjct: 1426 RVDVLDVNDNPPEFLRTQYDVTVSEALLPGSIIVTLVSRDNDSTANGLVRF--DILSGDK 1483

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP--VS 127
                                FR+   SG+++   SLD E+   YT+L++A D   P  VS
Sbjct: 1484 -----------------NSTFRVT-ESGSIILNKSLDYEQTKEYTLLLRARDVGLPPLVS 1525

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            DR    AT+ + ++D ND+ P F    Y+    E+ SV  +  + +++ATD D   NS I
Sbjct: 1526 DR---NATVLIRVVDLNDHQPVFDLSQYSGVFMENTSVGSS--LLRVRATDQDSNMNSHI 1580

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y  +  +  + F ++  +G+++L++ LD+E    Y  ++ A D G   ++  T + I +
Sbjct: 1581 SY-YMNTSQGLPFDVNQTNGEITLIRALDFETRSFYSFIVVASDAGRNRKAVNTLVQIYV 1639

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D+NDNAP F+  ++  ++SE    G  I +V A D D   NA+L + ++     GN + 
Sbjct: 1640 MDINDNAPVFFPIVYDVTISEATLQGAIIAKVTANDNDSLSNAQLRFAISQ----GNENG 1695

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               I+  +G +  +  +D E    Y L +T  D G PP + +                 +
Sbjct: 1696 SFAIND-AGILILAHAIDFENTRMYDLTITVHDLGWPPLATSKPARVIIHVYDDNDNSPI 1754

Query: 368  PGQ--YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG-RFSITSQNGRGL 422
             GQ  YEV L E+ P G   + ++ATD D   ++ L Y I         F IT + G   
Sbjct: 1755 FGQTVYEVTLKENYPVGQAFLNVSATDRDSRHNSLLSYSIHDAQANAPHFRITDETGE-- 1812

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            + ++  LD++    +  TV A D G   R  T +VQ+ + D N+  P+F+   Y  ++ E
Sbjct: 1813 LRLSSSLDYEARDVFRFTVIARDHGSSPRMGTTLVQVLVQDVNDNRPMFDPYCYNTTISE 1872

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            +   G  V+ VSA D+D   NA + Y +S+        + +  F I   TG I     LD
Sbjct: 1873 NLLPGMPVVWVSAYDNDSSSNADLKYRISA-------GNKENAFEITA-TGQIRPVIALD 1924

Query: 541  RETMSGYLLTVTARDGGVPSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
             E    Y LT+  RD G P+L       V I V DVNDN P+F Q LY+A I ED  VG 
Sbjct: 1925 HERTGFYNLTIDVRDSGQPALHAMHPATVLIHVFDVNDNAPIFNQTLYSAIIPEDFTVGG 1984

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            ++  V A D D  LN R+ Y +     E   FVID  +GV+R++K  D E+   +     
Sbjct: 1985 TLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVR 2044

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A D G+P +S+   +H++I D ND+ P+F+       +SEN+P+GT +  ++A D D   
Sbjct: 2045 AEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTS 2104

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL- 774
            NA + YSI+ G+++ SF+++   G    E++T  + D+E   ++Y L I  +    P L 
Sbjct: 2105 NADLIYSIQNGNNNGSFTIDNSTG----EIMTRKEFDFEK-TERYNLTISVSDTGVPALS 2159

Query: 775  -WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830
              N   V I+V D NDN P     +     Y++ F VG     V A D D  +   + Y 
Sbjct: 2160 SLNFANVVIIVVDENDNPPEFAQKRYTATVYEN-FTVGDNLFTVKASDKDSHLNGLITYS 2218

Query: 831  ILSGNN-ANLILLNETTGSMTLS 852
            I S  + A   +++E  G+++++
Sbjct: 2219 ITSAPSFAGKFVIDEILGNVSIT 2241



 Score =  353 bits (868), Expect = 1e-96
 Identities = 266/879 (30%), Positives = 413/879 (46%), Gaps = 60/879 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            QI V+D ND++PVF    Y+ ++ E    G  +  + A D D   NA++ + I      +
Sbjct: 1636 QIYVMDINDNAPVFFPIVYDVTISEATLQGAIIAKVTANDNDSLSNAQLRFAI------S 1689

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               E+               F I+  +G L+   ++D E    Y + +   D   P    
Sbjct: 1690 QGNENGS-------------FAIND-AGILILAHAIDFENTRMYDLTITVHDLGWPPL-A 1734

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S  A + +++ DDNDN P F +  Y V++ E+  V        + ATD D   NS + Y
Sbjct: 1735 TSKPARVIIHVYDDNDNSPIFGQTVYEVTLKENYPV--GQAFLNVSATDRDSRHNSLLSY 1792

Query: 190  AIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +I         F I   +G++ L  +LDYE    +R  + A+D GS  R  TT + + ++
Sbjct: 1793 SIHDAQANAPHFRITDETGELRLSSSLDYEARDVFRFTVIARDHGSSPRMGTTLVQVLVQ 1852

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P F    +  ++SEN+  G  +V V AYD D   NA+L Y ++     GN +  
Sbjct: 1853 DVNDNRPMFDPYCYNTTISENLLPGMPVVWVSAYDNDSSSNADLKYRIS----AGNKENA 1908

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXF 366
              I   +G +     LD E    Y L +   D G P   A   AT              F
Sbjct: 1909 FEITA-TGQIRPVIALDHERTGFYNLTIDVRDSGQPALHAMHPATVLIHVFDVNDNAPIF 1967

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y   + ED   G  ++T+ A D D   + R+ Y I   +T   + +   N  G++ 
Sbjct: 1968 NQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVID-NITGVVR 2026

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             ++  D++ +R Y  +V A D G   RS  A + + ITD N+  P+F+   Y   V E+ 
Sbjct: 2027 SSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENT 2086

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P+GT V  V A D D   NA + YS+ +  +N +       F I+  TG I T K  D E
Sbjct: 2087 PLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGS-------FTIDNSTGEIMTRKEFDFE 2139

Query: 543  TMSGYLLTVTARDGGVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
                Y LT++  D GVP+LS     +V I VVD NDN P F Q+ YTA + E+  VG ++
Sbjct: 2140 KTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGDNL 2199

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              V A+D D  LNG I Y +       G FVID   G +      D E   ++D    A 
Sbjct: 2200 FTVKASDKDSHLNGLITYSITSAPSFAGKFVIDEILGNVSITSGFDFELEQSYDFVIEAR 2259

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G+PP ++    H+ I D+ND+ PVF  +     ++E + +GT +  + AHD D GPNA
Sbjct: 2260 DSGSPPHTAYAHAHVTILDVNDNAPVFPVNNTHLVLTEATEVGTVVLRVTAHDKDSGPNA 2319

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777
            ++ YSI  G+  ++F +     +D  ++     LD E+  + Y LV+       PPL + 
Sbjct: 2320 MLKYSIHSGNTDDAFVII----ADSGDISLDKPLDKET-IENYTLVLIVTDMGIPPLESI 2374

Query: 778  VR--VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT--DKLQYRIL 832
             R  V ++V+ VN++AP   + +    +  +  P+G    RV A + DV+   +  Y I 
Sbjct: 2375 KRMVVNVIVSGVNEHAPRFLN-EFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIK 2433

Query: 833  SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
               ++ + L+N+ TG +TL+ +L+    +    EV   D
Sbjct: 2434 DAASSKVFLVNQ-TGDITLARELDYETRRRYEFEVFARD 2471



 Score =  346 bits (851), Expect = 1e-94
 Identities = 256/799 (32%), Positives = 391/799 (48%), Gaps = 60/799 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D ND+SP+F    YE +++E    G   L + ATD+D   N+ + Y+I    A+  
Sbjct: 1743 IHVYDDNDNSPIFGQTVYEVTLKENYPVGQAFLNVSATDRDSRHNSLLSYSIHDAQANAP 1802

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK--VARYTVLVKATDQASPVSD 128
            +                  FRI   +G L   +SLD E   V R+TV+  A D  S  S 
Sbjct: 1803 H------------------FRITDETGELRLSSSLDYEARDVFRFTVI--ARDHGS--SP 1840

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            R+ +T  + V + D NDN P F    Y  ++ E++ +   PV+  + A D D  +N+ ++
Sbjct: 1841 RMGTTL-VQVLVQDVNDNRPMFDPYCYNTTISENL-LPGMPVVW-VSAYDNDSSSNADLK 1897

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLIN 246
            Y I  GN +  F I + +G +  V  LD+E+   Y L I  +D G P+    +   +LI+
Sbjct: 1898 YRISAGNKENAFEITA-TGQIRPVIALDHERTGFYNLTIDVRDSGQPALHAMHPATVLIH 1956

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVNDNAP F  +L+   + E+  +G +++ V A D D  +NA +TY++    ++   D
Sbjct: 1957 VFDVNDNAPIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVS--FSTESD 2014

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                ID  +G V +S + D ETQ  Y   V A D G P RSA AT              F
Sbjct: 2015 Y-FVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIF 2073

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLIT 424
             P +YE  ++E+ P GT V  + A D D  +   L Y I  GN  G F+I   N  G I 
Sbjct: 2074 QPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGSFTI--DNSTGEIM 2131

Query: 425  VAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
              +  DF++  RY LT+S +D+G       + A V I + D N+  P F    YTA+V+E
Sbjct: 2132 TRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYE 2191

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            +  +G  +  V A+D D  +N  ITYS++S  S         +FVI+   G ++     D
Sbjct: 2192 NFTVGDNLFTVKASDKDSHLNGLITYSITSAPSFAG------KFVIDEILGNVSITSGFD 2245

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             E    Y   + ARD G P  +      ++++DVNDN PVF        + E   VGT V
Sbjct: 2246 FELEQSYDFVIEARDSGSPPHTAYAHAHVTILDVNDNAPVFPVNNTHLVLTEATEVGTVV 2305

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
             +V A D D G N  + Y +   + ++ +FVI   SG I  +K LD+E++  + L  +  
Sbjct: 2306 LRVTAHDKDSGPNAMLKYSIHSGNTDD-AFVIIADSGDISLDKPLDKETIENYTLVLIVT 2364

Query: 661  DGGTPPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            D G PP  S   ++V++ +  +N+  P F ++     I EN P+GT+I  +RA + D   
Sbjct: 2365 DMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSV 2424

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP-PL 774
             A   Y IK    S  F +     +   ++    +LDYE+ R++YE  + A    +P P 
Sbjct: 2425 GARFIYVIKDAASSKVFLV-----NQTGDITLARELDYET-RRRYEFEVFARDDGTPEPR 2478

Query: 775  WNDVRVEILVTDVNDNAPV 793
                 V I + D+NDN PV
Sbjct: 2479 EGLCVVTISLLDINDNRPV 2497



 Score =  334 bits (822), Expect = 4e-91
 Identities = 255/822 (31%), Positives = 404/822 (49%), Gaps = 73/822 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I ++D ND+ P F   +Y   + E  + GTTV  L A+D D   N +V ++I    +D 
Sbjct: 4933 RITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQLTASDLDSSLNGKVLFSILEGNSD- 4991

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID  +G + T  SLD E V  YT++++ATD   P  + 
Sbjct: 4992 ------------------GKFSIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNS 5033

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIR 188
             S    +HV++++ NDN P FS+K Y+ S+DE+ +V    VI +++ATD D V ++S + 
Sbjct: 5034 -SQPGMLHVSVVNINDNSPVFSQKIYSASIDENTTV--GHVILRVQATDRDHVNSSSIVI 5090

Query: 189  YAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG----------GSPS 236
            Y++   +T+    F+I++ +G++ LV +LDYE  + Y+  + A D           G  +
Sbjct: 5091 YSLDQSDTEAMRYFAINNQTGELILVSSLDYESTKGYQFTVFAGDNIAQFRKNRDIGDQA 5150

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            R     + I+I D+NDN P+F     +  ++E       I+ +QA DAD G+NA+L Y++
Sbjct: 5151 RVAAVLIDISILDINDNRPKFPQPYNKIEITEGTRESTMILTLQATDADSGMNAKLVYSI 5210

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXX 354
             +    G      T+DP +G + TS +LDRET  +Y L +T  D GDP  +A  TAT   
Sbjct: 5211 LNTTSNGT----FTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQTATVSI 5266

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRF 412
                       F    Y V + E+   G  ++ L A D DE  +  + Y +       RF
Sbjct: 5267 TVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAEILYFLKDVIASKRF 5326

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470
            S+    G+  IT+ Q +D+++   Y   V A+DSG    + ++ V+I I D N+  P F 
Sbjct: 5327 SMNDTTGQ--ITIKQAVDYEERSSYSFEVFASDSGEARLTGSSSVRIPIIDVNDNRPYFL 5384

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               Y   + E+  IGTTV  V A+D D  +N ++ +S+          + D +FVI+  T
Sbjct: 5385 PTRYYVQLVENVAIGTTVTQVYASDLDSSLNGKVLFSILE-------GNSDGKFVIDQNT 5437

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588
            G +TTNK LD E ++ Y L + A D G P L+ +    + +SVV++NDN PVF Q++Y+A
Sbjct: 5438 GVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNIPVFSQKMYSA 5497

Query: 589  NIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALD 646
            +I E+ +VG  + +V ATD D V  +  + Y LD  D E    F I+  +G +    +LD
Sbjct: 5498 SIDENTMVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRYFTINNQTGELILVSSLD 5557

Query: 647  RESVATHDLKAVAIDGGTPPQS-------STVIVHIKIEDINDSPPVFESDCLTFYISEN 699
             ES   +     A+D     +S        +  + I + +IND+ P F        ++EN
Sbjct: 5558 YESTKRYQFTVFALDNAMRSRSRRDSSNLGSCEIEISLGNINDNRPYFSPVEYNIEVAEN 5617

Query: 700  SPIGTTIGEIRAHDPDE-GP-NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
               GT++  + A D D+  P N  V +++     S S             L     L++E
Sbjct: 5618 VSPGTSLLLLHARDLDDVNPDNPDVIFTMIEQQPSLSMEQSIFAIQRDGTLSLNRTLNFE 5677

Query: 758  SPRKKYELVIRAAS---PPLWNDVR--VEILVTDVNDNAPVM 794
              R  Y + I  A    PPL   V   V ++V D ND  P +
Sbjct: 5678 E-RSSYNVTIAVADNGVPPLRCLVPAVVRVMVVDYNDGVPFL 5718



 Score =  309 bits (759), Expect = 2e-83
 Identities = 252/876 (28%), Positives = 402/876 (45%), Gaps = 86/876 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ V D ND+ P+F+   Y  ++ E    G  V+ + A D D   NA+++Y I       
Sbjct: 1848 QVLVQDVNDNRPMFDPYCYNTTISENLLPGMPVVWVSAYDNDSSSNADLKYRISAG---- 1903

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N E+A              F I   +G +    +LD E+   Y + +   D   P    
Sbjct: 1904 -NKENA--------------FEITA-TGQIRPVIALDHERTGFYNLTIDVRDSGQPALHA 1947

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +   AT+ +++ D NDN P F++  Y+  + ED +V     +  + A D D   N+ + Y
Sbjct: 1948 MHP-ATVLIHVFDVNDNAPIFNQTLYSAIIPEDFTV--GGTLLTVLARDQDAALNARVTY 2004

Query: 190  AIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +I+  +T+   F ID+++G V   K  DYE  R Y   +RA+D GSP RS    + + I 
Sbjct: 2005 SIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQIT 2064

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P F    ++  VSEN P+G  + RV+A D D   NA+L Y++ +    GN +  
Sbjct: 2065 DTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQN----GNNNGS 2120

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXF 366
             TID  +G + T  + D E   +Y L ++ +D G P  S+   A               F
Sbjct: 2121 FTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEF 2180

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT-RGRFSITSQNGRGLI 423
               +Y   + E+   G  + T+ A+D D   +  + Y IT   +  G+F I    G   +
Sbjct: 2181 AQKRYTATVYENFTVGDNLFTVKASDKDSHLNGLITYSITSAPSFAGKFVIDEILGN--V 2238

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFED 481
            ++    DF+ E+ Y   + A DSG    TA    ++T  D N+ APVF        + E 
Sbjct: 2239 SITSGFDFELEQSYDFVIEARDSGSPPHTAYAHAHVTILDVNDNAPVFPVNNTHLVLTEA 2298

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              +GT VL V+A D D G NA + YS+ S        + D  FVI   +G I+ +K LD+
Sbjct: 2299 TEVGTVVLRVTAHDKDSGPNAMLKYSIHS-------GNTDDAFVIIADSGDISLDKPLDK 2351

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTANIMEDALVGTS 599
            ET+  Y L +   D G+P L     + ++V+   VN++ P F  + Y A+I E+  +GTS
Sbjct: 2352 ETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTS 2411

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + +V A + DV +  R  Y +  KD       +   +G I   + LD E+   ++ +  A
Sbjct: 2412 IVRVRAVEDDVSVGARFIYVI--KDAASSKVFLVNQTGDITLARELDYETRRRYEFEVFA 2469

Query: 660  IDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
             D GTP P+    +V I + DIND+ PVF     +  ISE+  +G+T+G I  +D     
Sbjct: 2470 RDDGTPEPREGLCVVTISLLDINDNRPVFTKGENSISISEDVRVGSTLGFIIVND----- 2524

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
                           S   ET    +    +T+V  D  SPR      + +  P     V
Sbjct: 2525 ---------------SLDFETTASYN----LTIVAFDSGSPR------LASLVPA---TV 2556

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836
             V++L  D NDN P+    +     Y++         + A+D D  +  ++ Y I++ + 
Sbjct: 2557 FVKVL--DANDNPPIFNQSEYYVEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSV 2614

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
              +   N TTG ++L+ +L+        M V   DG
Sbjct: 2615 KGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDG 2650



 Score =  285 bits (700), Expect = 3e-76
 Identities = 219/756 (28%), Positives = 361/756 (47%), Gaps = 63/756 (8%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEY 60
            S P  +H  ++V++ ND+SPVF  + Y AS+ E  + G  +L ++ATD+D +  ++ V Y
Sbjct: 5034 SQPGMLH--VSVVNINDNSPVFSQKIYSASIDENTTVGHVILRVQATDRDHVNSSSIVIY 5091

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
            +++   +DT                    F I+ ++G L+  +SLD E    Y   V A 
Sbjct: 5092 SLD--QSDT---------------EAMRYFAINNQTGELILVSSLDYESTKGYQFTVFAG 5134

Query: 121  DQAS------PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
            D  +       + D+    A  I ++I+D NDN P+F +    + + E     ++ +I  
Sbjct: 5135 DNIAQFRKNRDIGDQARVAAVLIDISILDINDNRPKFPQPYNKIEITE--GTRESTMILT 5192

Query: 174  IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            ++ATDAD G N+ + Y+I+   +   F++D  +G +   + LD E V  Y L I   D G
Sbjct: 5193 LQATDADSGMNAKLVYSILNTTSNGTFTVDPHTGVLRTSQRLDRETVTEYTLTITVHDSG 5252

Query: 234  SP--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
             P  + + T  + I + D NDN P F   ++  S+ EN+ +G  I+ + A D DEGVNAE
Sbjct: 5253 DPMLNAAQTATVSITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAE 5312

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            + Y +  KD   +     +++  +G +     +D E ++ Y   V A+D G+   + +++
Sbjct: 5313 ILYFL--KDVIAS--KRFSMNDTTGQITIKQAVDYEERSSYSFEVFASDSGEARLTGSSS 5368

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409
                          F+P +Y V+L E+   GT V  + A+D D   + ++ + I  GN+ 
Sbjct: 5369 VRIPIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVYASDLDSSLNGKVLFSILEGNSD 5428

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465
            G+F +  QN  G++T  + LD++    Y L + ATD G      S   M+ +++ + N+ 
Sbjct: 5429 GKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDN 5486

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQF 524
             PVF    Y+AS+ E+  +G  +L V ATD D V  ++ + YSL  +   EA+ +    F
Sbjct: 5487 IPVFSQKMYSASIDENTMVGHVILRVQATDRDHVNSSSIVIYSL-DQSDTEAMRY----F 5541

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-------DTTDVEISVVDVNDN 577
             IN QTG +     LD E+   Y  TV A D  + S S        + ++EIS+ ++NDN
Sbjct: 5542 TINNQTGELILVSSLDYESTKRYQFTVFALDNAMRSRSRRDSSNLGSCEIEISLGNINDN 5601

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDA-DVGL-NGRIHY---ELDPKDREEGSFVI 632
             P F    Y   + E+   GTS+  + A D  DV   N  + +   E  P    E S   
Sbjct: 5602 RPYFSPVEYNIEVAENVSPGTSLLLLHARDLDDVNPDNPDVIFTMIEQQPSLSMEQSIFA 5661

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV--IVHIKIEDINDSPPVFESD 690
                G +  N+ L+ E  +++++     D G PP    V  +V + + D ND  P   S 
Sbjct: 5662 IQRDGTLSLNRTLNFEERSSYNVTIAVADNGVPPLRCLVPAVVRVMVVDYNDGVPFLTSP 5721

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
                 I   S  GT    I+A D D G    + Y I
Sbjct: 5722 TGVILIDWASSPGTIATVIQASDHDSGSAGFISYFI 5757



 Score =  276 bits (677), Expect = 2e-73
 Identities = 249/898 (27%), Positives = 395/898 (43%), Gaps = 54/898 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ PVF    YEA V            +KA D D  +N  + Y++    +   
Sbjct: 1181 IRIRDDNDNQPVFSRDLYEAWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSKFR 1240

Query: 71   NPEDAXXXXXXXXXXVQD----VFRIDGRSGALLTRASLDREKVARYTV----------L 116
              E             ++    VF I      +  ++S    KV    V          L
Sbjct: 1241 VNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFL 1300

Query: 117  VKAT-DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK 175
             K+T  + SPV       + + + I D+NDN P F    Y V + E++S+  +  I ++ 
Sbjct: 1301 YKSTVRENSPVGTTAIKVSVVLL-IEDENDNPPVFDLPYYFVRMYENVSIRAD--IIRVH 1357

Query: 176  ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
            A+D+D G NS IRY+   G     F+I++ +G +     +D+E+ R Y   + A D G P
Sbjct: 1358 ASDSDSGFNSEIRYSFPVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIP 1417

Query: 236  SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
               +   + +++ DVNDN P F  + +  +VSE +  G  IV + + D D   N  + + 
Sbjct: 1418 VLRDVAIVRVDVLDVNDNPPEFLRTQYDVTVSEALLPGSIIVTLVSRDNDSTANGLVRFD 1477

Query: 296  MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXX 353
            +   D   N    +T    SG +  +  LD E   +Y LL+ A D G PP      AT  
Sbjct: 1478 ILSGD--KNSTFRVT---ESGSIILNKSLDYEQTKEYTLLLRARDVGLPPLVSDRNATVL 1532

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RF 412
                        F   QY     E+   G+ ++ + ATD D +   H       ++G  F
Sbjct: 1533 IRVVDLNDHQPVFDLSQYSGVFMENTSVGSSLLRVRATDQDSNMNSHISYYMNTSQGLPF 1592

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470
             +   NG   IT+ + LDF+    Y   V A+D+G   ++   +VQI + D N+ APVF 
Sbjct: 1593 DVNQTNGE--ITLIRALDFETRSFYSFIVVASDAGRNRKAVNTLVQIYVMDINDNAPVFF 1650

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               Y  ++ E    G  +  V+A D+D   NAQ+ +++S    NE     +  F IN   
Sbjct: 1651 PIVYDVTISEATLQGAIIAKVTANDNDSLSNAQLRFAISQ--GNE-----NGSFAIN-DA 1702

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTA 588
            G +     +D E    Y LT+T  D G P L  S    V I V D NDN P+F Q +Y  
Sbjct: 1703 GILILAHAIDFENTRMYDLTITVHDLGWPPLATSKPARVIIHVYDDNDNSPIFGQTVYEV 1762

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
             + E+  VG +   V ATD D   N  + Y +         F I   +G +R + +LD E
Sbjct: 1763 TLKENYPVGQAFLNVSATDRDSRHNSLLSYSIHDAQANAPHFRITDETGELRLSSSLDYE 1822

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            +        +A D G+ P+  T +V + ++D+ND+ P+F+  C    ISEN   G  +  
Sbjct: 1823 ARDVFRFTVIARDHGSSPRMGTTLVQVLVQDVNDNRPMFDPYCYNTTISENLLPGMPVVW 1882

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI- 767
            + A+D D   NA + Y I  G+  N+F + T  G    ++  ++ LD+E     Y L I 
Sbjct: 1883 VSAYDNDSSSNADLKYRISAGNKENAFEI-TATG----QIRPVIALDHER-TGFYNLTID 1936

Query: 768  -RAASPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822
             R +  P     +   V I V DVNDNAP+           +D    G    V A D D 
Sbjct: 1937 VRDSGQPALHAMHPATVLIHVFDVNDNAPIFNQTLYSAIIPEDFTVGGTLLTVLARDQDA 1996

Query: 823  -VTDKLQYRILS-GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
             +  ++ Y I+S    ++  +++  TG +  S + +    ++ +  V   D  + I++
Sbjct: 1997 ALNARVTYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRS 2054



 Score =  226 bits (553), Expect = 2e-58
 Identities = 161/511 (31%), Positives = 246/511 (48%), Gaps = 40/511 (7%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            IH QI   D ND+ P+F+  +YE  V E    GT V  +KA D+D   NA++ Y+I+   
Sbjct: 2059 IHVQIT--DTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQ--- 2113

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                N  +               F ID  +G ++TR   D EK  RY + +  +D   P 
Sbjct: 2114 ----NGNN------------NGSFTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPA 2157

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               L + A + + ++D+NDN P+F++K YT +V E+ +V DN  +  +KA+D D   N  
Sbjct: 2158 LSSL-NFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGDN--LFTVKASDKDSHLNGL 2214

Query: 187  IRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            I Y+I    +   +F ID + G+VS+    D+E  +SY  VI A+D GSP  +      +
Sbjct: 2215 ITYSITSAPSFAGKFVIDEILGNVSITSGFDFELEQSYDFVIEARDSGSPPHTAYAHAHV 2274

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             I DVNDNAP F  +     ++E   +G  ++RV A+D D G NA L Y++    ++GN 
Sbjct: 2275 TILDVNDNAPVFPVNNTHLVLTEATEVGTVVLRVTAHDKDSGPNAMLKYSI----HSGNT 2330

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXX 363
            D    I   SG +     LD+ET   Y L++  TD G PP  +                 
Sbjct: 2331 DDAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHA 2390

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG 421
              F+   Y   + E+ P GT +V + A + D     R  Y I    +   F +   N  G
Sbjct: 2391 PRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLV---NQTG 2447

Query: 422  LITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478
             IT+A+ LD++  RRY   V A D G    R    +V I++ D N+  PVF     + S+
Sbjct: 2448 DITLARELDYETRRRYEFEVFARDDGTPEPREGLCVVTISLLDINDNRPVFTKGENSISI 2507

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
             ED  +G+T+  +   DS +      +Y+L+
Sbjct: 2508 SEDVRVGSTLGFIIVNDS-LDFETTASYNLT 2537



 Score =  206 bits (502), Expect = 3e-52
 Identities = 162/588 (27%), Positives = 282/588 (47%), Gaps = 56/588 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND+ PVF+ + Y  S+ E  + G  +L L A D+D G NAE+ Y ++ V A   
Sbjct: 5266 ITVLDENDNVPVFDQEVYSVSIPENITVGAHILLLNARDKDEGVNAEILYFLKDVIASKR 5325

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ++  +G +  + ++D E+ + Y+  V A+D       RL
Sbjct: 5326 -------------------FSMNDTTGQITIKQAVDYEERSSYSFEVFASDSGEA---RL 5363

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + ++++ + IID NDN P F    Y V + E++++     + ++ A+D D   N  + ++
Sbjct: 5364 TGSSSVRIPIIDVNDNRPYFLPTRYYVQLVENVAI--GTTVTQVYASDLDSSLNGKVLFS 5421

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIR 248
            I+ GN+  +F ID  +G V+  K+LDYE V  Y LVI+A D G P  + S    L +++ 
Sbjct: 5422 ILEGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVV 5481

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            ++NDN P F   ++  S+ EN  +G+ I+RVQA D D   ++ +     D+  T  +   
Sbjct: 5482 NINDNIPVFSQKMYSASIDENTMVGHVILRVQATDRDHVNSSSIVIYSLDQSDTEAMRY- 5540

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-------ATATXXXXXXXXXX 361
             TI+ ++G +     LD E+  +YQ  V A D     RS        +            
Sbjct: 5541 FTINNQTGELILVSSLDYESTKRYQFTVFALDNAMRSRSRRDSSNLGSCEIEISLGNIND 5600

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-- 419
                F P +Y +E+AE+  PGT ++ L A D D+ N  + ++       + S++ +    
Sbjct: 5601 NRPYFSPVEYNIEVAENVSPGTSLLLLHARDLDDVNPDNPDVIFTMIEQQPSLSMEQSIF 5660

Query: 420  ----RGLITVAQPLDFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPVFEN 471
                 G +++ + L+F++   Y +T++  D+G         A+V++ + D N+  P   +
Sbjct: 5661 AIQRDGTLSLNRTLNFEERSSYNVTIAVADNGVPPLRCLVPAVVRVMVVDYNDGVPFLTS 5720

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS-------EISNEAVAHHDQQ- 523
                  +   +  GT   V+ A+D D G    I+Y +S+         S++     +Q  
Sbjct: 5721 PTGVILIDWASSPGTIATVIQASDHDSGSAGFISYFISNITGLPTLTTSSDFARCVNQTY 5780

Query: 524  --FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
              F I+  TG +  + +L    +  Y +TVTARD GVP LS +  ++I
Sbjct: 5781 GVFDIHEHTGTLRVSGILASSCL--YNVTVTARDHGVPPLSSSVILQI 5826



 Score =  163 bits (395), Expect = 2e-39
 Identities = 161/603 (26%), Positives = 268/603 (44%), Gaps = 61/603 (10%)

Query: 315  SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYE 372
            SG +  + +LD E    Y L V A D G P   +   A               F    YE
Sbjct: 1140 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYE 1199

Query: 373  VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
              +  +         + A DAD  ++ RL Y +   N++ R + T+    G I +++ LD
Sbjct: 1200 AWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSKFRVNETT----GEIYLSESLD 1255

Query: 431  FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            F++ + YV  + A+DSG   +S +  V++ +   N+  P F+   Y ++V E++P+GTT 
Sbjct: 1256 FEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFLYKSTVRENSPVGTTA 1315

Query: 489  LVVSAT-----DSD-----------------VGINAQITYSLSSE----ISNEAVAHHDQ 522
            + VS       ++D                 V I A I    +S+     ++E       
Sbjct: 1316 IKVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDSDSGFNSEIRYSFPV 1375

Query: 523  QFVINP-----QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
             FV+ P      TG I T   +D E    Y  +V A D G+P L D   V + V+DVNDN
Sbjct: 1376 GFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIPVLRDVAIVRVDVLDVNDN 1435

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
             P F +  Y   + E  L G+ +  + + D D   NG + +++   D+     V +  SG
Sbjct: 1436 PPEFLRTQYDVTVSEALLPGSIIVTLVSRDNDSTANGLVRFDILSGDKNSTFRVTE--SG 1493

Query: 638  VIRTNKALDRESVATHDLKAVAIDGGTPPQSS--TVIVHIKIEDINDSPPVFESDCLTFY 695
             I  NK+LD E    + L   A D G PP  S     V I++ D+ND  PVF+    +  
Sbjct: 1494 SIILNKSLDYEQTKEYTLLLRARDVGLPPLVSDRNATVLIRVVDLNDHQPVFDLSQYSGV 1553

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
              EN+ +G+++  +RA D D   N+ + Y +   + S     +  Q + +  L+    LD
Sbjct: 1554 FMENTSVGSSLLRVRATDQDSNMNSHISYYM---NTSQGLPFDVNQTNGEITLIRA--LD 1608

Query: 756  YESPRKKYELVIRAASPPLWN---DVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVG 811
            +E+ R  Y  ++ A+         +  V+I V D+NDNAPV   F I+++    +    G
Sbjct: 1609 FET-RSFYSFIVVASDAGRNRKAVNTLVQIYVMDINDNAPVF--FPIVYDVTISEATLQG 1665

Query: 812  P-FGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
                +V A D D     +L++ I  GN      +N+  G + L+  ++    ++  + ++
Sbjct: 1666 AIIAKVTANDNDSLSNAQLRFAISQGNENGSFAIND-AGILILAHAIDFENTRMYDLTIT 1724

Query: 869  VTD 871
            V D
Sbjct: 1725 VHD 1727



 Score =  104 bits (250), Expect = 9e-22
 Identities = 60/184 (32%), Positives = 97/184 (52%), Gaps = 5/184 (2%)

Query: 96   SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
            SG +     LD E++  Y + V A D   PV   L   A + + I DDNDN P FS   Y
Sbjct: 1140 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKP-ANVVIRIRDDNDNQPVFSRDLY 1198

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215
               V   +     PV   +KA DAD   N  + Y+++  N++  F ++  +G++ L ++L
Sbjct: 1199 EAWVL--VEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSK--FRVNETTGEIYLSESL 1254

Query: 216  DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
            D+E+ + Y   I A D G   +S++T + + +  VNDN P F   L++ +V EN P+G +
Sbjct: 1255 DFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFLYKSTVRENSPVGTT 1314

Query: 276  IVRV 279
             ++V
Sbjct: 1315 AIKV 1318



 Score = 90.2 bits (214), Expect = 2e-17
 Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 14/199 (7%)

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANN 464
            RGR  +   N  G I++A+ LD+++ + Y LTV A DSG         A V I I D N+
Sbjct: 1130 RGRGHLLLVNS-GEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDND 1188

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              PVF    Y A V  +         + A D+D   N ++ YS+           ++ +F
Sbjct: 1189 NQPVFSRDLYEAWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSM---------VRNNSKF 1239

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
             +N  TG I  ++ LD E    Y+  + A D GV   S +T V++ V+ VNDN P F + 
Sbjct: 1240 RVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRF 1299

Query: 585  LYTANIMEDALVGTSVSQV 603
            LY + + E++ VGT+  +V
Sbjct: 1300 LYKSTVRENSPVGTTAIKV 1318



 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 52/193 (26%), Positives = 86/193 (44%), Gaps = 8/193 (4%)

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT--TQLLINIRDVNDNAPRFYTSLFQ 263
            SG++S+ + LDYE+++ Y L + A D G P   +     ++I IRD NDN P F   L++
Sbjct: 1140 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYE 1199

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
              V            ++A DAD   N  L Y+M   +          ++  +G +Y S  
Sbjct: 1200 AWVLVEYHRWPVRRAMKAKDADYQQNGRLVYSMVRNNSK------FRVNETTGEIYLSES 1253

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            LD E   +Y   + A+D G  P+S++ +              F    Y+  + E+ P GT
Sbjct: 1254 LDFEETKEYVFGIIASDSGVEPKSSSTSVKVIVMHVNDNVPTFDRFLYKSTVRENSPVGT 1313

Query: 384  PVVTLTATDADED 396
              + ++     ED
Sbjct: 1314 TAIKVSVVLLIED 1326


>SB_38622| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 3824

 Score =  385 bits (947), Expect = e-106
 Identities = 284/886 (32%), Positives = 427/886 (48%), Gaps = 70/886 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +N+ D ND+ P F    Y AS+ E + SG+ V+ L A D DIG+N+ + Y+I       L
Sbjct: 665  VNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI-------L 717

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                 F +D R G +    +LD E  + YT  V ATD         
Sbjct: 718  TPNTP--------------FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGR----- 758

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S  AT+HV++ D NDN P F   +Y+V   E+  +  +  I ++KA D D    +  R+ 
Sbjct: 759  SCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS--ICQLKAIDRDSPKFAITRFI 816

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN    FS+D  SG ++L K LD E   +Y L ++A DGG     N   + I + DV
Sbjct: 817  IEQGNADEVFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDV 875

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  P F  + +  ++ E+      I  V A   D+G NAE+ Y+++     GN D  + 
Sbjct: 876  NDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISK----GNTDNIVL 931

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G +Y   ++D E      L V A D G PP    A               F    
Sbjct: 932  INS-TGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSS 990

Query: 371  YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              V L ED P G    T++  DAD     R+ + +   N    F++ S  G   +++ + 
Sbjct: 991  ILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLS-NPGTLFNLDSNTGA--LSLTKL 1047

Query: 429  LDF-KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            +D+    R Y L V A D G   RS TAM+++ + D N+Y+PVF N  YTA V E  P  
Sbjct: 1048 IDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPD 1107

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            + ++ V ATD D G N +I+Y+  S++          +F +    G I     LDRE + 
Sbjct: 1108 SNIIEVVATDVDSGENGRISYAFDSKVDTS-------KFGLR-NGGKIFIKSKLDREDIE 1159

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y L V A D G P  S + DV++ V DVNDN P F+Q  Y   + E+  V T +  V A
Sbjct: 1160 EYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSA 1219

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            +D+D G NG + Y  D    +   F++D  +G I T++ LDRE+ A++    VA DGG+ 
Sbjct: 1220 SDSDEGSNGHVTYRFDT---QVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSS 1276

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAVVHY 724
            P+     V + + D+ND  P F  +  +  ++E+ P+G+++  + A D D+ GPN+ + Y
Sbjct: 1277 PRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITY 1336

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI---RAASPPLWNDVRV 780
             I  G    +FSL    G     ++T+V  LD E   +    V+   +  +  L     +
Sbjct: 1337 MIVAGP--KAFSLNQVTG-----VLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYI 1389

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQYRILSGNNA 837
            EI V DVNDN PV  + +  F    +  P+G     V A D+D  D  K++Y+I++GN  
Sbjct: 1390 EINVLDVNDNYPVFIN-ETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTD 1448

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQL 882
                +NETTG ++    L+  V     + VS TD G  + K   QL
Sbjct: 1449 GTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQL 1494



 Score =  363 bits (892), Expect = 1e-99
 Identities = 281/874 (32%), Positives = 419/874 (47%), Gaps = 64/874 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +INV D ND +P F+   YE  V E A+  T V  + A DQD G N+E+ YTI    A+T
Sbjct: 555  RINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTI----ANT 610

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID  SG + T   LDRE++ +  + V   D+ SP    
Sbjct: 611  TESRSYLHW-----------FAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPP--- 656

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LS   ++ VN+ D NDN P F++ +Y  S+ E+ S + +PV+ ++ A D D+G NS I Y
Sbjct: 657  LSDNCSVIVNLTDSNDNDPYFNQSSYNASLFEN-SPSGSPVV-QLLAQDPDIGENSLILY 714

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I+  NT   F +D   G V+  +TLD+E   SY   + A DGG  S + T    +++ D
Sbjct: 715  SILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVH--VSLTD 770

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P F  S +     EN  IG SI +++A D D    A   + +      GN D   
Sbjct: 771  LNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQ----GNADEVF 826

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            ++D  SG +  +  LDRETQ  Y L V A DGG       A               F   
Sbjct: 827  SVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKA 885

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427
            +Y   + E     + +  + A   D+       Y I+ GNT    +I   N  G + +  
Sbjct: 886  EYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTD---NIVLINSTGTLYLQS 942

Query: 428  PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             +D ++     LTV A D G       A V I + D N+ +P F ++     + ED PIG
Sbjct: 943  EVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIG 1002

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR-ETM 544
             T   VS  D+D G+  ++++SL   +SN         F ++  TGA++  KL+D   + 
Sbjct: 1003 HTFYTVSVFDADSGVLGRVSFSL---LSNPGTL-----FNLDSNTGALSLTKLIDYGNSA 1054

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              Y L V A+DGG P  S T  +E+ VVDVND  PVF    YTA+++E     +++ +V 
Sbjct: 1055 RSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVV 1114

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D G NGRI Y  D K  +   F +     +   +K LDRE +  ++LK +AID GT
Sbjct: 1115 ATDVDSGENGRISYAFDSKV-DTSKFGLRNGGKIFIKSK-LDREDIEEYNLKVIAIDHGT 1172

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P +SS+  V + ++D+ND+ P F+     F++ EN P+ T +G + A D DEG N   H 
Sbjct: 1173 PRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNG--HV 1230

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            + +       F ++ + G    ++ T   LD E+ +  Y   I A    S P  +  +V 
Sbjct: 1231 TYRFDTQVAQFIVDKQTG----KITTSQVLDREA-KASYVFSIVATDGGSSPRVDKTQVT 1285

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD---VTDKLQYRILSGNNA 837
            ++V DVND +P     +      +D  PVG     + A D D       + Y I++G  A
Sbjct: 1286 VIVRDVNDCSPKFSKNKYSVTVNED-LPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKA 1344

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                LN+ TG +TL   L+  V     + V  +D
Sbjct: 1345 --FSLNQVTGVLTLVSPLDREVTHRHILHVVASD 1376



 Score =  359 bits (883), Expect = 2e-98
 Identities = 252/821 (30%), Positives = 395/821 (48%), Gaps = 49/821 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P F    Y  ++ E    GT++L + A+D+DIG NAE++Y+IE  +    
Sbjct: 339  ITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHS---- 394

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P              Q +F I   +G ++    LD E    Y ++VKA D+ S  S +L
Sbjct: 395  DP--------------QAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGS--SHQL 438

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGANSAIR 188
            SS+A + + ++D NDN P     +YT+     +  + T    +A++  +DAD G N  + 
Sbjct: 439  SSSAIVRIEVLDVNDNNPVI-HVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVN 497

Query: 189  YAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
              + GG+       D L+ +  +++ ++LD E    + L     D G P R+      IN
Sbjct: 498  VTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRIN 557

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVND AP+F    ++  V EN  +   +  V A D D G N+EL YT+ +   + +  
Sbjct: 558  VGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYL 617

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                IDP SG + T+  LDRE   +  L V   D G PP S   +              F
Sbjct: 618  HWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYF 677

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y   L E+ P G+PVV L A D D  E++ + Y I   NT   F +  +  +GL+T
Sbjct: 678  NQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNT--PFFLDPR--KGLVT 733

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
             ++ LD + +  Y   V+ATD GGRS  A V +++TD N+  PVF+ + Y+   FE+  I
Sbjct: 734  NSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRI 793

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G ++  + A D D        ++++  I  +  A  D+ F ++  +G IT  KLLDRET 
Sbjct: 794  GQSICQLKAIDRD-----SPKFAITRFIIEQGNA--DEVFSVD-GSGLITLAKLLDRETQ 845

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              YLLTV A DGG     +   V I+V+DVND  P+F +  Y   I E +   + +  V 
Sbjct: 846  DNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVH 905

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A   D G N  + Y +   + +  + V+  ++G +     +D E + +  L   A D GT
Sbjct: 906  AISRDKGTNAEVVYSISKGNTD--NIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGT 963

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            PP      V I + DIND+ P F S  +   + E++PIG T   +   D D G    V +
Sbjct: 964  PPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSF 1023

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            S+   +    F+L++  G+    L  ++  DY +  + Y L ++A    SPP  +   +E
Sbjct: 1024 SLL-SNPGTLFNLDSNTGA--LSLTKLI--DYGNSARSYTLPVQAQDGGSPPRSSTAMLE 1078

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
            + V DVND +PV  ++    +  +   P      V A D D
Sbjct: 1079 LKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVD 1119



 Score =  356 bits (876), Expect = 1e-97
 Identities = 272/876 (31%), Positives = 412/876 (47%), Gaps = 60/876 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P F+       + E     T V T+KA D D G N+ + YTI     D+ 
Sbjct: 1497 IYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTI-----DSQ 1551

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P                 F+I+  +G + T   +DRE+++ Y++ V+ATDQA    DRL
Sbjct: 1552 SPRAH--------------FKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRL 1597

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +TAT+ + I D NDN P+F  +  T  ++++     N  +  I A D D G    + Y 
Sbjct: 1598 YNTATLKIIIQDLNDNAPKFVSRNLTYVMEDE---PFNFQVTSITALDPDTGQGGNVEYR 1654

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+  +T  +FS+D  +G + L+ +LDYE V  Y L I A D GSP  ++     + + DV
Sbjct: 1655 IVSPDTG-KFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDV 1713

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F   LF  +VSEN P G S+V+V AYD D G NAELTY++     +G      +
Sbjct: 1714 NDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIP----SGVEMDKFS 1769

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ID  SG + T+  LDRE +  Y L V AT    P R ++ +              F+   
Sbjct: 1770 IDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPV 1829

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              +++ E+  P   + TLT  D D  N  ++ Y I  GNT G F+I    G   ++    
Sbjct: 1830 VTLKVPENS-PARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGE--LSTTTK 1886

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD + +  Y L+V A D      TA   I   I D N+  PVF+ + Y++++ E  P GT
Sbjct: 1887 LDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGT 1946

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            ++L ++A+D D G N  I Y+LS++            + I+ +TG + +    +      
Sbjct: 1947 SILNLTASDKDSGSNGNIVYTLSNDTYG--------VYSIDSRTGIVYSAARFETSIKQE 1998

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y     A+D G         V I + D N++ P F +  Y  +I  +      V+ V AT
Sbjct: 1999 YNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTAT 2058

Query: 607  DADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            DAD     NG++ Y LD        FV++  +G +RT+          H L  +A D G+
Sbjct: 2059 DADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGS 2118

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            PP     IV I I +I D PP F +       I ENS +G+ I  +RA       +A V 
Sbjct: 2119 PPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR---ASSDAQVT 2175

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---- 779
            YSI  G+   +F ++   G     + +   LDYES  K + L +  A+P  W  +     
Sbjct: 2176 YSIISGNKGRAFYVDPFTG--VISVASADALDYES-TKNFRLHL-VATPQGWVSLNGYMI 2231

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDAD--VTDKLQYRILSGN 835
            ++I V D NDN+P      ++    +D     P    +V A D D     K+ Y I +GN
Sbjct: 2232 LDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGN 2291

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             A +  ++ TTG +T +  L+        + +  TD
Sbjct: 2292 EAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTD 2327



 Score =  351 bits (863), Expect = 5e-96
 Identities = 265/876 (30%), Positives = 396/876 (45%), Gaps = 60/876 (6%)

Query: 10   QINVLDCNDHSPVFEMQQY---EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +I VLD ND++PV  +         V E A+ GT V  +  +D D GKN EV  T+E   
Sbjct: 445  RIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLE--- 501

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                                   F +      +    SLDRE    + +     D+  P 
Sbjct: 502  --------------GGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPP 547

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                ++  +  +N+ D ND  P+F   TY   V E+ +V  N ++A + A D D G+NS 
Sbjct: 548  R---TTEKSFRINVGDVNDCAPKFDRHTYETRVWENATV--NTLVAIVNAVDQDFGSNSE 602

Query: 187  IRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            + Y I            F+ID  SG ++    LD EQ+    L +   D GSP  S+   
Sbjct: 603  LVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCS 662

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            +++N+ D NDN P F  S +  S+ EN P G  +V++ A D D G N+ + Y++     T
Sbjct: 663  VIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI----LT 718

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
             N   P  +DPR G V  S  LD E Q+ Y   V ATDGG   RS  AT           
Sbjct: 719  PNT--PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDN 774

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGR 420
               F P  Y VE  E+   G  +  L A D D        + I  GN    FS+   +G 
Sbjct: 775  QPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSV---DGS 831

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASV 478
            GLIT+A+ LD + +  Y+LTV A D GG+   + A+V I + D N+  P+F  A Y  ++
Sbjct: 832  GLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTI 891

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E +   + +  V A   D G NA++ YS+S         + D   +IN  TG +     
Sbjct: 892  QEHSQALSVIGHVHAISRDKGTNAEVVYSISK-------GNTDNIVLIN-STGTLYLQSE 943

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            +D E +    LTV A+D G P L    +V I+V+D+NDN P F        + ED  +G 
Sbjct: 944  VDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGH 1003

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKA 657
            +   V   DAD G+ GR+ + L         F +D  +G +   K +D   S  ++ L  
Sbjct: 1004 TFYTVSVFDADSGVLGRVSFSL--LSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPV 1061

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A DGG+PP+SST ++ +K+ D+ND  PVF +   T ++ E +P  + I E+ A D D G
Sbjct: 1062 QAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSG 1121

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
             N  + Y+     D++ F L  R G  K  + + +D +         + I   +P   + 
Sbjct: 1122 ENGRISYAFDSKVDTSKFGL--RNGG-KIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSS 1178

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNN 836
              V+++V DVNDN P  +     F   K+  PV  + G V A D+D              
Sbjct: 1179 ADVKVIVDDVNDNNPHFQQASYAF-FVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQ 1237

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                ++++ TG +T S  L+          +  TDG
Sbjct: 1238 VAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDG 1273



 Score =  348 bits (856), Expect = 3e-95
 Identities = 271/895 (30%), Positives = 423/895 (47%), Gaps = 59/895 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+SP F ++   A +    +       L A D D G N+   YTI  V+ +  
Sbjct: 225  VYVQDLNDNSPSF-VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTI--VSGNVG 281

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                D+  ++  S        +DRE++  Y + + A+D  +P +   
Sbjct: 282  NVFKLISKRDTDGDLYADLV-VNASS------IGVDRERLDSYVLNISASDGGNPAN--- 331

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + + + D NDN P+FS  +Y+ ++ E+I V  +  I ++ A+D D+G N+ I+Y+
Sbjct: 332  HGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTS--ILQVSASDKDIGTNAEIQYS 389

Query: 191  I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIR 248
            I    + Q  F I   +G +     LDYE  RSY +V++A+D GS  + +++ ++ I + 
Sbjct: 390  IETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVL 449

Query: 249  DVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            DVNDN P     YT      V+EN  IG  + RV   DAD G N E+  T+   D  G  
Sbjct: 450  DVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGD--GYF 507

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
             +   +      +     LDRET   + L     D GDPPR+   +              
Sbjct: 508  SMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPK 567

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS----ITSQNGRG 421
            F    YE  + E+    T V  + A D D  +      T  NT    S           G
Sbjct: 568  FDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSG 627

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            +IT A  LD +Q  + VLTV   D G    SD   V +N+TD+N+  P F  + Y AS+F
Sbjct: 628  MITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLF 687

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E++P G+ V+ + A D D+G N+ I YS+ +          +  F ++P+ G +T ++ L
Sbjct: 688  ENSPSGSPVVQLLAQDPDIGENSLILYSILTP---------NTPFFLDPRKGLVTNSRTL 738

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D E  S Y   V A DGG  S + T  V +S+ D+NDN+PVF    Y+    E+  +G S
Sbjct: 739  DHEVQSSYTFQVAATDGGGRSCNAT--VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS 796

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + Q+ A D D        + ++  + +E  F +D  SG+I   K LDRE+   + L   A
Sbjct: 797  ICQLKAIDRDSPKFAITRFIIEQGNADE-VFSVD-GSGLITLAKLLDRETQDNYLLTVKA 854

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            +DGG     +  IV+I + D+ND PP+F      F I E+S   + IG + A   D+G N
Sbjct: 855  VDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTN 914

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
            A V YSI  G+  N   +     +    L    ++D+E     Y L ++A    +PPL+ 
Sbjct: 915  AEVVYSISKGNTDNIVLI-----NSTGTLYLQSEVDHEKIPSLY-LTVQAKDKGTPPLFG 968

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILS 833
               V I V D+NDN+P      I+    +D  P+G  F  V  +DAD  V  ++ + +LS
Sbjct: 969  YANVTIAVIDINDNSPQFNSSSILVRLPEDT-PIGHTFYTVSVFDADSGVLGRVSFSLLS 1027

Query: 834  GNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK---AMMQLSV 884
             N   L  L+  TG+++L+  ++  N  +  T+ V   DG +  +   AM++L V
Sbjct: 1028 -NPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKV 1081



 Score =  339 bits (833), Expect = 2e-92
 Identities = 257/856 (30%), Positives = 410/856 (47%), Gaps = 63/856 (7%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTADTLN 71
            V D ND SP F   +Y  +V E    G+++LTL ATD D  G N+++ Y I         
Sbjct: 1288 VRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMI------VAG 1341

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
            P+                F ++  +G L   + LDRE   R+ + V A+D+    S  L 
Sbjct: 1342 PK---------------AFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQS--LE 1384

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            +   I +N++D NDNYP F  +T   +V E + +    V+A + A D+D G N  +RY I
Sbjct: 1385 TITYIEINVLDVNDNYPVFINETTFKTVPEKLPI--GSVVAAVLAVDSDQGDNGKVRYKI 1442

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDV 250
            + GNT   F I+  +G +S ++ LD+E    Y L + A D G   +  + QL+ I + D 
Sbjct: 1443 VNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDA 1502

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  +     + ENVPI  ++  ++A+D D G+N+ + YT+  +    +      
Sbjct: 1503 NDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAH----FK 1558

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA---TATXXXXXXXXXXXXXXFM 367
            I+  +G + T+  +DRE  ++Y L V ATD     +     TAT              F+
Sbjct: 1559 INSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFV 1618

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
              +    + EDEP    V ++TA D D  +   + Y I   +T G+FS+  +   G++ +
Sbjct: 1619 -SRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDT-GKFSLDLKT--GVLKL 1674

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAP 483
               LD++   +Y L +SATD G    T+  +  + + D N+  P F    +  +V E+ P
Sbjct: 1675 IGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKP 1734

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT+V+ V+A D D G NA++TYS+ S +  +       +F I+  +G I TN +LDRE 
Sbjct: 1735 TGTSVVKVTAYDRDSGSNAELTYSIPSGVEMD-------KFSIDKHSGLIVTNSILDREK 1787

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
               Y LTV A     P    +T V I+V+D NDN P F   + T  + E++     +  +
Sbjct: 1788 KDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS-PARLIYTL 1846

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
               D D G N ++ Y +      +G+F I  ++G + T   LDRE+ A++ L   A D  
Sbjct: 1847 TVQDLDYGNNTKVLYSI-MSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDIT 1905

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P  ++   + I IED ND+PPVF+    +  ISE +P GT+I  + A D D G N  + 
Sbjct: 1906 PPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIV 1965

Query: 724  YSIKGGDDSNSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
            Y++   D    +S+++R G     A   T +  +Y      + +       P    V V 
Sbjct: 1966 YTL-SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNF----FCIAKDQGQDPKMAIVPVR 2020

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD----VTDKLQYRI-LSGNN 836
            I + D N++AP         + + +         V A DAD       K+ YR+  S N+
Sbjct: 2021 IKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNS 2080

Query: 837  ANLILLNETTGSMTLS 852
             +L ++   TGS+  S
Sbjct: 2081 TSLFVVESNTGSVRTS 2096



 Score =  330 bits (811), Expect = 9e-90
 Identities = 244/779 (31%), Positives = 377/779 (48%), Gaps = 43/779 (5%)

Query: 90   FRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            F +D  +G +   ++  LD E    + + + AT Q   VS  L+    + +N+ID NDN 
Sbjct: 2187 FYVDPFTGVISVASADALDYESTKNFRLHLVATPQGW-VS--LNGYMILDINVIDRNDNS 2243

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P F        + ED        + K+ ATD D G N  + Y+I  GN    F+IDS +G
Sbjct: 2244 PAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTG 2303

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            +++  K LD E   S+ LVIR  D G P +S   Q+ + + D+NDN P F   L + ++ 
Sbjct: 2304 EITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLF-DPLSEVNIR 2362

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            E+   G  +  V A D D+   + LTY +      G      ++   +G V    +LD E
Sbjct: 2363 EDTRTGAVVTSVVATDTDK--ESRLTYNLKSASTPG----MFSVGRFNGAVSLLKRLDYE 2416

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
               KY L +  +DG     SA  T              F+   Y+V L++  P G  ++ 
Sbjct: 2417 KTNKYSLNIAVSDG---LHSAEKTLTINVLDTNDNTPKFLNSSYQVTLSKTIPAGRAILR 2473

Query: 388  LTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATD 445
            ++ATD D  +    + +   T   +         G+I+  + +D +    ++ + V A D
Sbjct: 2474 VSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMD 2533

Query: 446  SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQI 504
             G     A+V + I       P FE   Y   V E+A +GT+VL V  TD+  G+   +I
Sbjct: 2534 QGVPPQRALVYVRIIITRE--PKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRI 2591

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
            +Y++  E SN         F I  ++G I+ NK LD ET   +LL V+A D   PS    
Sbjct: 2592 SYNI--ENSN--------YFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVR 2641

Query: 565  TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
              V I+V DVND +PVF Q  Y A   E   VGT V  V A D D G NGR+ + +   D
Sbjct: 2642 VPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGD 2701

Query: 625  REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
             ++GSF ID  +GVIRT +ALD E++ TH +   A D G+PP  + V V I++ D+ND+P
Sbjct: 2702 -DKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNP 2760

Query: 685  PVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            PVF         + EN P+ + + EI A D D G NA + +++ GG     F ++   G 
Sbjct: 2761 PVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSG- 2819

Query: 744  DKAELVTMVDLDYESPR-KKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQI 799
                L T +  DYE+    +Y L I+   A +PPL +++ + + V D ++  P       
Sbjct: 2820 ---WLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDY 2876

Query: 800  IFNNYKDCFPVGPF-GRVPAYDADVTDKLQ-YRILSGNNANLILLNETTGSMTLSPQLN 856
             F+   +   +G F G+V A D D  D+ + + +     +N + +N TTG ++++  LN
Sbjct: 2877 KFDVPGNA-KIGDFVGQVTATDRDSGDQGRVFFVFYNPTSNALKMNATTGIISVNRTLN 2934



 Score =  327 bits (804), Expect = 7e-89
 Identities = 234/796 (29%), Positives = 380/796 (47%), Gaps = 54/796 (6%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           ++  +G + T+  LDREKV+ Y + +   + ++P       + T+ V + D NDN P F 
Sbjct: 186 LEYNAGVITTKTVLDREKVSAYNLTI--VEFSTP-----PKSYTVLVYVQDLNDNSPSFV 238

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS---LSGD 208
             T    V   +   D     K+ A D+D G+NS   Y I+ GN    F + S     GD
Sbjct: 239 RGTSAKLV---VFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGD 295

Query: 209 V--SLVKT-----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
           +   LV       +D E++ SY L I A DGG+P+     +L I + D NDN P F    
Sbjct: 296 LYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVS 355

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           +  ++ EN+ +G SI++V A D D G NAE+ Y++   +   +      I P +G +  +
Sbjct: 356 YSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSI---ETHSDPQAIFGIHPTTGVIVNN 412

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV----ELAE 377
            +LD E +  Y ++V A D G   + +++                +   Y +    ++ E
Sbjct: 413 VRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTE 472

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQPLDFKQER 435
           +   GT V  ++ +DAD        +T     G FS+     N   +I V Q LD +   
Sbjct: 473 NATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHD 532

Query: 436 RYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            + L     D G   R+     +IN+ D N+ AP F+   Y   V+E+A + T V +V+A
Sbjct: 533 HFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNA 592

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D D G N+++ Y++++   + +  H    F I+P +G ITT   LDRE +   +LTV  
Sbjct: 593 VDQDFGSNSELVYTIANTTESRSYLHW---FAIDPSSGMITTATDLDREQIPQVVLTVLV 649

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            D G P LSD   V +++ D NDN+P F Q  Y A++ E++  G+ V Q+ A D D+G N
Sbjct: 650 HDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGEN 709

Query: 614 GRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
             I Y  L P       F +DP  G++  ++ LD E  +++  +  A DGG   +S    
Sbjct: 710 SLILYSILTPNT----PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGG--GRSCNAT 763

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           VH+ + D+ND+ PVF+    +    EN+ IG +I +++A D D    A+  + I+ G+  
Sbjct: 764 VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNAD 823

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789
             FS+      D + L+T+  L     +  Y L ++A         N   V I V DVND
Sbjct: 824 EVFSV------DGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVND 877

Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847
             P+    +  F   +    +   G V A   D     ++ Y I  GN  N++L+N +TG
Sbjct: 878 EPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLIN-STG 936

Query: 848 SMTLSPQL-NTNVPKL 862
           ++ L  ++ +  +P L
Sbjct: 937 TLYLQSEVDHEKIPSL 952



 Score =  316 bits (776), Expect = 2e-85
 Identities = 246/805 (30%), Positives = 377/805 (46%), Gaps = 65/805 (8%)

Query: 2    SVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59
            S P   +Q  NV+  D ND+ P F    +  +V E   +GT+V+ + A D+D G NAE+ 
Sbjct: 1697 SPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELT 1756

Query: 60   YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
            Y+I         P               D F ID  SG ++T + LDREK   Y + V A
Sbjct: 1757 YSI---------PSGVE----------MDKFSIDKHSGLIVTNSILDREKKDTYFLTVHA 1797

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
            T  + P   R+SST ++ +N++D NDN P+F     T+ V E+   +   +I  +   D 
Sbjct: 1798 TGVSYPF--RVSST-SVRINVMDRNDNPPKFISPVVTLKVPEN---SPARLIYTLTVQDL 1851

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            D G N+ + Y+I+ GNT   F+I   +G++S    LD E   SY+L ++A+D   P  + 
Sbjct: 1852 DYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTA 1911

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               + I I D NDN P F  SL+  ++SE  P G SI+ + A D D G N  + YT+++ 
Sbjct: 1912 FANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSND 1971

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
             Y        +ID R+G VY++ + +   + +Y     A D G  P+ A           
Sbjct: 1972 TYG-----VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDK 2026

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-----GGNTRGRFSI 414
                  F    YEV +  +      V  +TATDAD D   + ++T       N+   F +
Sbjct: 2027 NNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVV 2086

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN- 471
             S  G   +  +       + R+ L + A D G        +VQI I +  +  P F N 
Sbjct: 2087 ESNTGS--VRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQ 2144

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
             P   S+ E++ +G+ +  V A  S    +AQ+TYS+ S        +  + F ++P TG
Sbjct: 2145 TPARVSIPENSKVGSYITTVRARASS---DAQVTYSIIS-------GNKGRAFYVDPFTG 2194

Query: 532  AIT--TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             I+  +   LD E+   + L + A   G  SL+    ++I+V+D NDN P F      A 
Sbjct: 2195 VISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQ 2254

Query: 590  IMED--ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
            + ED  A     V +V ATD D G NG++ Y +     E G F ID  +G I T K LDR
Sbjct: 2255 LAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSI-WTGNEAGVFTIDSTTGEITTAKLLDR 2313

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E+ A+ DL     D G PP+S+   V + + D+ND+PP+F+       I E++  G  + 
Sbjct: 2314 ETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFD-PLSEVNIREDTRTGAVVT 2372

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
             + A D D+   + + Y++K       FS+    G     +  +  LDYE    KY L I
Sbjct: 2373 SVVATDTDK--ESRLTYNLKSASTPGMFSV----GRFNGAVSLLKRLDYEK-TNKYSLNI 2425

Query: 768  RAASPPLWNDVRVEILVTDVNDNAP 792
              +      +  + I V D NDN P
Sbjct: 2426 AVSDGLHSAEKTLTINVLDTNDNTP 2450



 Score =  310 bits (761), Expect = 1e-83
 Identities = 252/856 (29%), Positives = 390/856 (45%), Gaps = 59/856 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +INVLD ND+ PVF  +    +V E    G+ V  + A D D G N +V Y  ++V  +T
Sbjct: 1390 EINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRY--KIVNGNT 1447

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F+I+  +G + T  +LD E   RY + V ATD        
Sbjct: 1448 -----------------DGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKT 1490

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                 TI+V   D NDN P F +      + E++ +  N  +  IKA D D G NS I Y
Sbjct: 1491 SYQLVTIYVE--DANDNRPTFDKNPIITWIYENVPINTN--VTTIKAHDDDSGLNSRIWY 1546

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS---NTTQLLIN 246
             I   + +  F I+S +G +     +D E++  Y L +RA D     +    NT  L I 
Sbjct: 1547 TIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKII 1606

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I+D+NDNAP+F  S     V E+ P  + +  + A D D G    + Y +   D TG   
Sbjct: 1607 IQDLNDNAPKF-VSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPD-TGK-- 1662

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               ++D ++G +   G LD E   +Y L ++ATD G PP ++                 F
Sbjct: 1663 --FSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEF 1720

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLIT 424
                +   ++E++P GT VV +TA D D  +   L Y I  G    +FSI   +  GLI 
Sbjct: 1721 TRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHS--GLIV 1778

Query: 425  VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
                LD +++  Y LTV AT      R  +  V+IN+ D N+  P F +   T  V E++
Sbjct: 1779 TNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS 1838

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P    +  ++  D D G N ++ YS+ S        + D  F I   TG ++T   LDRE
Sbjct: 1839 P-ARLIYTLTVQDLDYGNNTKVLYSIMS-------GNTDGAFTIGRSTGELSTTTKLDRE 1890

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            T + Y L+V A+D   P  +   ++ I + D NDN PVF+Q LY++ I E    GTS+  
Sbjct: 1891 TKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILN 1950

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            + A+D D G NG I Y L   +   G + ID  +G++ +    +      ++   +A D 
Sbjct: 1951 LTASDKDSGSNGNIVYTL--SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQ 2008

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNA 720
            G  P+ + V V IKIED N+  P F       +I  N+     +  + A   D D+  N 
Sbjct: 2009 GQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNG 2068

Query: 721  VVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
             V Y +    +S S F +E+  GS +    T        P+ ++ L I A    SPPL  
Sbjct: 2069 KVTYRLDDSKNSTSLFVVESNTGSVR----TSAGFS-NPPQGRHALYIIAEDHGSPPLRG 2123

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836
               V+I++ ++ D+ P   +      +  +   VG +       A    ++ Y I+SGN 
Sbjct: 2124 YGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQVTYSIISGNK 2183

Query: 837  ANLILLNETTGSMTLS 852
                 ++  TG ++++
Sbjct: 2184 GRAFYVDPFTGVISVA 2199



 Score =  306 bits (752), Expect = 1e-82
 Identities = 233/743 (31%), Positives = 351/743 (47%), Gaps = 62/743 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVRE--GASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            INV+D ND+SP F      A + E  GA     V+ + ATD D G N +V Y+I      
Sbjct: 2234 INVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIW----- 2288

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            T N                 VF ID  +G + T   LDRE  A + ++++ TD   P   
Sbjct: 2289 TGNEAG--------------VFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPK- 2333

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              S+   + V + D NDN P F +    V++ ED       V+  + ATD D    S + 
Sbjct: 2334 --STNCQVKVVVTDLNDNPPLF-DPLSEVNIRED--TRTGAVVTSVVATDTD--KESRLT 2386

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y +   +T   FS+   +G VSL+K LDYE+   Y L I   DG     S    L IN+ 
Sbjct: 2387 YNLKSASTPGMFSVGRFNGAVSLLKRLDYEKTNKYSLNIAVSDG---LHSAEKTLTINVL 2443

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P+F  S +Q ++S+ +P G +I+RV A D D G NA++ Y+      T +  + 
Sbjct: 2444 DTNDNTPKFLNSSYQVTLSKTIPAGRAILRVSATDQDSGSNAQIKYSF---PITNSDQID 2500

Query: 309  ITIDPRSGWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              ID  +G +     +D R   +  Q+ V A D G PP+ A                 F 
Sbjct: 2501 YKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALV----YVRIIITREPKFE 2556

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLIT 424
               Y  ++ E+   GT V+T+  TD        R+ Y I   N    F I  ++  G+I+
Sbjct: 2557 LPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSN---YFRIGQRS--GVIS 2611

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDA 482
            V +PLD++ +RR++L VSA D    S      V IN++D N+  PVF  + Y A   E  
Sbjct: 2612 VNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGI 2671

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P+GT V+ VSA D D G N ++ +++ S             F I+ +TG I T + LD E
Sbjct: 2672 PVGTIVVNVSAADKDSGANGRVWFAIQS-------GDDKGSFAIDRKTGVIRTQRALDHE 2724

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSVS 601
            T+  + ++V A D G P +     V I V+D+NDN PVF+        ++E+  + + + 
Sbjct: 2725 TIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLY 2784

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT--HDLKAVA 659
            ++ ATD D G N R+ + +      +G F+ID  SG + TN   D E+ A   + L   A
Sbjct: 2785 EINATDRDSGANARLSFTV-IGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKA 2843

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D G PP SS + + + + D ++  P F      F +  N+ IG  +G++ A D D G  
Sbjct: 2844 TDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQ 2903

Query: 720  AVVHYSIKGGDDSNSFSLETRQG 742
              V + +     SN+  +    G
Sbjct: 2904 GRVFF-VFYNPTSNALKMNATTG 2925



 Score =  254 bits (622), Expect = 8e-67
 Identities = 248/898 (27%), Positives = 401/898 (44%), Gaps = 81/898 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ PVF+   Y +++ E    GT++L L A+D+D G N  + YT+   + DT 
Sbjct: 1917 IFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTL---SNDTY 1973

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              V+ ID R+G + + A  +      Y     A DQ     D  
Sbjct: 1974 G-----------------VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQG---QDPK 2013

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIR 188
             +   + + I D N++ PQF++  Y V +  + S   + ++  + ATDAD     N  + 
Sbjct: 2014 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSA--SALVTMVTATDADTDKSTNGKVT 2071

Query: 189  YAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            Y +    N+   F ++S +G V             + L I A+D GSP       + I I
Sbjct: 2072 YRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVI 2131

Query: 248  RDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
             ++ D+ PRF      + S+ EN  +G  I  V+A  + +   A++TY++     +GN  
Sbjct: 2132 GNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSD---AQVTYSI----ISGNKG 2184

Query: 307  LPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                +DP +G   V ++  LD E+   ++L + AT  G    +                 
Sbjct: 2185 RAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSP 2244

Query: 365  XFMPGQYEVELAEDEPPGTP--VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420
             F P     +LAED     P  VV +TATD D   + ++ Y I  GN  G F+I S  G 
Sbjct: 2245 AFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGE 2304

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
              IT A+ LD +    + L +  TDSG   +S    V++ +TD N+  P+F+      ++
Sbjct: 2305 --ITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLS-EVNI 2361

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             ED   G  V  V ATD+D    +++TY+L S       A     F +    GA++  K 
Sbjct: 2362 REDTRTGAVVTSVVATDTDK--ESRLTYNLKS-------ASTPGMFSVGRFNGAVSLLKR 2412

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LD E  + Y L +   D G+ S   T  + I+V+D NDN P F    Y   + +    G 
Sbjct: 2413 LDYEKTNKYSLNIAVSD-GLHSAEKT--LTINVLDTNDNTPKFLNSSYQVTLSKTIPAGR 2469

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKA 657
            ++ +V ATD D G N +I Y     + ++  + ID  +GVI   + +D R   +   +  
Sbjct: 2470 AILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPV 2529

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A+D G PPQ + V V I    I    P FE       + EN+ +GT++  +R  D   G
Sbjct: 2530 QAMDQGVPPQRALVYVRI----IITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAG 2585

Query: 718  -PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
             P   + Y+I   ++SN F +  R G     +     LDYE+ ++++ LV+ A    +P 
Sbjct: 2586 LPLGRISYNI---ENSNYFRIGQRSG----VISVNKPLDYET-KRRFLLVVSAIDDTAPS 2637

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYR 830
                V V I V+DVND  PV      +   + +  PVG     V A D D     ++ + 
Sbjct: 2638 KPVRVPVYINVSDVNDEKPVFGQSGYM-AQWSEGIPVGTIVVNVSAADKDSGANGRVWFA 2696

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
            I SG++     ++  TG +     L+    K   + V  TD G   +   + +++R++
Sbjct: 2697 IQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVL 2754



 Score =  253 bits (619), Expect = 2e-66
 Identities = 223/798 (27%), Positives = 346/798 (43%), Gaps = 60/798 (7%)

Query: 1    MSVPFCIHQ---QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE 57
            +S PF +     +INV+D ND+ P F        V E  S    + TL   D D G N +
Sbjct: 1800 VSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPEN-SPARLIYTLTVQDLDYGNNTK 1858

Query: 58   VEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117
            V Y+I  ++ +T                    F I   +G L T   LDRE  A Y + V
Sbjct: 1859 VLYSI--MSGNT-----------------DGAFTIGRSTGELSTTTKLDRETKASYQLSV 1899

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177
            +A D   P     ++ A I + I D NDN P F +  Y+ ++ E         I  + A+
Sbjct: 1900 QAKDITPPY---YTAFANITIFIEDQNDNPPVFQQSLYSSTISE--LTPPGTSILNLTAS 1954

Query: 178  DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
            D D G+N  I Y  +  +T   +SIDS +G V      +    + Y     A+D G   +
Sbjct: 1955 DKDSGSNGNIVYT-LSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPK 2013

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA--DEGVNAELTYT 295
                 + I I D N++AP+F  + ++  +  N      +  V A DA  D+  N ++TY 
Sbjct: 2014 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYR 2073

Query: 296  MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
            + D   + ++     ++  +G V TS       Q ++ L + A D G PP          
Sbjct: 2074 LDDSKNSTSL---FVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIV 2130

Query: 356  XXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414
                      F+      V + E+   G+ + T+ A  A  D ++ Y I  GN    F +
Sbjct: 2131 IGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR-ASSDAQVTYSIISGNKGRAFYV 2189

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA 472
                G   +  A  LD++  + + L + AT  G    +   ++ IN+ D N+ +P F  +
Sbjct: 2190 DPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPS 2249

Query: 473  PYTASVFED--APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               A + ED  A     V+ V+ATD D G N ++TYS+ +   NEA       F I+  T
Sbjct: 2250 NMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWT--GNEAGV-----FTIDSTT 2302

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G ITT KLLDRET + + L +   D G+P  S    V++ V D+NDN P+F   L   NI
Sbjct: 2303 GEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLF-DPLSEVNI 2361

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             ED   G  V+ V ATD D     R+ Y L       G F +   +G +   K LD E  
Sbjct: 2362 REDTRTGAVVTSVVATDTD--KESRLTYNLKSAS-TPGMFSVGRFNGAVSLLKRLDYEKT 2418

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
              + L  +A+  G      T+ +++   D ND+ P F +      +S+  P G  I  + 
Sbjct: 2419 NKYSLN-IAVSDGLHSAEKTLTINVL--DTNDNTPKFLNSSYQVTLSKTIPAGRAILRVS 2475

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
            A D D G NA + YS      +NS  ++ +  +D   +     +D        ++ ++A 
Sbjct: 2476 ATDQDSGSNAQIKYSF---PITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAM 2532

Query: 771  S---PPLWNDVRVEILVT 785
                PP    V V I++T
Sbjct: 2533 DQGVPPQRALVYVRIIIT 2550



 Score =  227 bits (554), Expect = 1e-58
 Identities = 172/587 (29%), Positives = 276/587 (47%), Gaps = 34/587 (5%)

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
           +P  ++  +G + T   LDRE  + Y L  T  +   PP+S T                F
Sbjct: 182 IPADLEYNAGVITTKTVLDREKVSAYNL--TIVEFSTPPKSYTV--LVYVQDLNDNSPSF 237

Query: 367 MPG-QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG------ 419
           + G   ++ + E++      +    +D   ++   Y I  GN    F + S+        
Sbjct: 238 VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLY 297

Query: 420 RGLITVAQPLDFKQER--RYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYT 475
             L+  A  +   +ER   YVL +SA+D G  ++   ++++IT  D N+  P F N  Y+
Sbjct: 298 ADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYS 357

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            ++ E+  +GT++L VSA+D D+G NA+I YS+ +    +A+      F I+P TG I  
Sbjct: 358 GTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAI------FGIHPTTGVIVN 411

Query: 536 NKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA----NI 590
           N  LD E    YL+ V A D G    LS +  V I V+DVNDN PV     YT      +
Sbjct: 412 NVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVS-YTLGGSYQV 470

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRES 649
            E+A +GT V++V  +DAD G NG ++  L+  D      F +     +I   ++LDRE+
Sbjct: 471 TENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRET 530

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
                LKAV ID G PP+++     I + D+ND  P F+       + EN+ + T +  +
Sbjct: 531 HDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIV 590

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR 768
            A D D G N+ + Y+I    +S S+            + T  DLD E  P+    +++ 
Sbjct: 591 NAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVH 650

Query: 769 -AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK- 826
              SPPL ++  V + +TD NDN P         + +++     P  ++ A D D+ +  
Sbjct: 651 DRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENS 710

Query: 827 -LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            + Y IL+ N      L+   G +T S  L+  V    T +V+ TDG
Sbjct: 711 LILYSILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDG 755



 Score =  134 bits (324), Expect = 1e-30
 Identities = 94/289 (32%), Positives = 143/289 (49%), Gaps = 27/289 (9%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S P  +   INV D ND  PVF    Y A   EG   GT V+ + A D+D G N  V + 
Sbjct: 2637 SKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFA 2696

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            I+       + +D            +  F ID ++G + T+ +LD E +  + V V+ATD
Sbjct: 2697 IQ-------SGDD------------KGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATD 2737

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDAD 180
            + SP    + +  ++ + ++D NDN P F       V V E++ +  N  + +I ATD D
Sbjct: 2738 EGSP---PMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPL--NSRLYEINATDRD 2792

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQDGGSPSRS 238
             GAN+ + + +IGG  Q  F ID  SG ++   T DYE   V  Y L I+A D G+P  S
Sbjct: 2793 SGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLS 2852

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287
            +   +++N+ D ++  P F    ++  V  N  IG  + +V A D D G
Sbjct: 2853 SNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSG 2901


>SB_25361| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 4833

 Score =  384 bits (945), Expect = e-106
 Identities = 260/766 (33%), Positives = 380/766 (49%), Gaps = 55/766 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+SP F    Y   + E A+ G ++ T+ A+D DIG+NA + Y+I       +
Sbjct: 1666 VTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSI-------V 1718

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +PE A              F ++  +G +     LDRE V  Y + V ATD     ++  
Sbjct: 1719 SPEKAT-------------FSMNPVTGEITVGQRLDREGVEHYLLNVTATDNGRLNTN-- 1763

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             ++  +++N++D NDN PQF    Y   + E       P++  +KA D D G+N  ++Y+
Sbjct: 1764 DASVDVYINVLDVNDNAPQFEAAVYHGEISESADKL-TPIVT-VKAIDKDSGSNGIVKYS 1821

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SPSRSNTTQLLINIRD 249
            +I GN    F+I   +G +   + LD E+  +Y L +RA D   S      T+++IN+ D
Sbjct: 1822 LISGNDGDAFTILG-NGTIVNAEVLDREKKSTYNLEVRAVDQATSGGLEGVTRVVINVTD 1880

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VND  P F TS     VSEN  +G  ++ V A DADEG N ++ Y++       ++  P 
Sbjct: 1881 VNDQPPEF-TSASVAHVSENSRVGDVVLTVIAVDADEGSNGDVVYSLGL-----DIGAPF 1934

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            ++  + G +  SG +DRE +A Y + VTATD G PP SA+                F+  
Sbjct: 1935 SLGSKDGVLRVSGSMDREKKANYSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFLSH 1994

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
               V + E+  PGT ++TL A D D   +  + Y    GN+   F+I S  GR  +  A+
Sbjct: 1995 IGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGR--LRTAR 2052

Query: 428  PLDFKQERRYVLTVSATDSG-GRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +   R+ L V A D G  R D+   V + + D N+  PVF  + Y A V E   + 
Sbjct: 2053 NLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VE 2111

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            + ++ V A D D+G +  +TY ++              FVIN  TG I     LDRET S
Sbjct: 2112 SNIVTVVAEDRDIGSDGSVTYCITQ-------GREGGLFVINENTGTIGITAKLDRETKS 2164

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y L V A DGG P+LS   DV ++V+D ND+ PVF     T  + ED   GT+V +V A
Sbjct: 2165 KYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSA 2224

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             D DVG N  + Y L         F ID  +GVI T + LDRE    H L+ +A D G P
Sbjct: 2225 VDGDVGSNADVTYSL---KYSFSRFSIDSKTGVITTVRPLDREIAGQHKLEVLASDAGKP 2281

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            P    + + I + D ND  P F+       IS+++P+GT +  + A D D G NA   YS
Sbjct: 2282 PLQGKLDLDIIVGDKNDHDPEFQQSQFQATISQSAPVGTIVFVLSARDEDTGENAESDYS 2341

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
            I  G+D++ FSL  R G      V  V     S   +Y L I+AA+
Sbjct: 2342 ITSGNDASVFSLNARSG------VISVSRTVPSSPAQYSLKIKAAN 2381



 Score =  358 bits (880), Expect = 4e-98
 Identities = 310/1112 (27%), Positives = 492/1112 (44%), Gaps = 88/1112 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ P F +  Y   + E ++ G TV+ + A D D G N E+ Y   L    +
Sbjct: 2694 KVTVTDINDNPPKFLLLPYVTQLPEDSAVGVTVMNVTAVDADEGTNVELNYEFLLSPYGS 2753

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                DA                   R+ A    ++L    +  Y + V+A +   P    
Sbjct: 2754 FLAVDARTGMITL-----------NRAIAFKPFSALPNPNI--YNLTVRARNIYPP---H 2797

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIR 188
              + A I + ++D ND+ P F +  Y +   +D        I +++A D  D G N+ +R
Sbjct: 2798 YKADAAIQIEVLDTNDHAPVFVKSVYLLFAVQDAG--SGVSIGRVEAVDKFDYGPNALVR 2855

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y  I GN   +F +   +G+V +  +L  +  ++Y + +RA D G P  S+T  + + + 
Sbjct: 2856 YEAISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVT 2915

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            + N + P F  +++Q S +E++ +G +++ V A D D G N E++Y +      GN    
Sbjct: 2916 ERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDII----AGNSQEY 2971

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              I   +G +Y S  LD E Q  Y L V+ATDGG  P+++ AT              F P
Sbjct: 2972 FGIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSP 3031

Query: 369  GQYEVELAEDEPPGTPVV-TLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425
             +Y  ELAE+  P + VV ++ ATD DE  +  + Y I GG+ + +F I  + G    TV
Sbjct: 3032 IEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKDKFVIDERTGEIRATV 3091

Query: 426  AQPLDFKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
                DF+      L ++A D G          A V I IT  N + PVF  + +TA+V E
Sbjct: 3092 E--FDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAE 3149

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            +APIG +VL VSATD D G +  + Y L         + + Q F ++  TG ++ +  LD
Sbjct: 3150 NAPIGHSVLRVSATDKDKGPDGVVLYHLLG-------SDNQQGFDLDSNTGTLSVSGDLD 3202

Query: 541  RETMSGYLLTVTARD----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
             E      L V A++       PS      + ++V D ND  P F + +Y+A++ E + +
Sbjct: 3203 NERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDAND-PPRFLKSVYSAHVTEGSRI 3261

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G  V+ V A D D  +   I Y +   +    +FV+D  +G +RT   LDRE++A + L 
Sbjct: 3262 GHVVTNVTAVDDDSDIRS-IRYGISAGNTGN-AFVMDAVTGFVRTAAELDREAIAEYRLT 3319

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
              A D GTPP +    + + ++DIND+PP          ++EN P GT +  + A DPD 
Sbjct: 3320 VTATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDL 3379

Query: 717  GPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
             PN     YSI  G D  SF L    G     + T+  LD E  +  Y + I+       
Sbjct: 3380 NPNRGPFKYSI-SGSDYGSFRLNVSSG----VVSTVKSLDREK-QDAYNISIKVTDARGL 3433

Query: 776  NDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
            + V    I V D NDN P      +  + ++  F  G    V   D D+ D +   +L+ 
Sbjct: 3434 SAVNFCMIHVEDQNDNRPKATSRDVYVHTFEGKFLGGVVADVRPDDPDIDDPMTCALLNP 3493

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894
               N  + +   G+  LS  L  +      + V+ +DG+  +  ++ L     TE  L  
Sbjct: 3494 PQNN--IFSFPRGNCELS-SLAYSQDARFDLSVNGSDGLGAVTYLITLRFLGYTETTLQQ 3550

Query: 895  SITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSAR 954
             + VRL +     FL+     F   + A +P    +  I SV    +    +++V  S R
Sbjct: 3551 GVVVRLRNTNTRDFLANSYHKFTSAVNATLPSGYSS-QIMSVDSSGE---GLVDVLASVR 3606

Query: 955  RPDAEVGVAGDPSPHYSPTHLRERVYLH-RTTLARLATVQVLPFDDNIC-VHEPCLNFEE 1012
            +    +              +R+RV  H +  L   + + +   D N C     CLN  E
Sbjct: 3607 QGGTLM--------------IRDRVSGHLKDKLVSSSALDIAAVDYNPCTTGNQCLNGGE 3652

Query: 1013 CLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI 1072
            C + ++       V+S  V+          TC C  GFTG  CE  +       D + + 
Sbjct: 3653 CSSAIQASRRGHVVSSTPVVMVTAGYTWKITCSCKPGFTGSQCEESVN------DCNPNP 3706

Query: 1073 CRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
            CR+   C     G      CS    YT  +CE
Sbjct: 3707 CRNEGTC-TDNNGSF---KCSCIPGYTGRLCE 3734



 Score =  348 bits (855), Expect = 4e-95
 Identities = 260/859 (30%), Positives = 407/859 (47%), Gaps = 71/859 (8%)

Query: 4    PFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            P     +I V+  D NDH PVF        + E AS GT ++TL+A D D G NAE+ Y 
Sbjct: 1970 PLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYA 2029

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
               VT ++ N                  F I+  +G L T  +LDRE   R+T+ V A D
Sbjct: 2030 --FVTGNSNNS-----------------FTINSITGRLRTARNLDRETTPRFTLEVLAYD 2070

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
               P   R  S   + V + D NDN P F+   Y   V E + V  N  I  + A D D+
Sbjct: 2071 LGVP---RKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VESN--IVTVVAEDRDI 2124

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            G++ ++ Y I  G     F I+  +G + +   LD E    Y L ++A DGGSP+ S+  
Sbjct: 2125 GSDGSVTYCITQGREGGLFVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEA 2184

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             +++N+ D ND+AP F  +     V E+   G ++++V A D D G NA++TY++    Y
Sbjct: 2185 DVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSL---KY 2241

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            + +     +ID ++G + T   LDRE   +++L V A+D G PP                
Sbjct: 2242 SFS---RFSIDSKTGVITTVRPLDREIAGQHKLEVLASDAGKPPLQGKLDLDIIVGDKND 2298

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                F   Q++  +++  P GT V  L+A D D  E+    Y IT GN    FS+ +++ 
Sbjct: 2299 HDPEFQQSQFQATISQSAPVGTIVFVLSARDEDTGENAESDYSITSGNDASVFSLNARS- 2357

Query: 420  RGLITVAQPLDFKQERRYVLTVSAT--DSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G+I+V++ +      +Y L + A   ++ GR+D+A +QI ++ A    P F +   + S
Sbjct: 2358 -GVISVSRTVP-SSPAQYSLKIKAANRNAPGRTDSATLQITVSSA--VFPRFLHPDQSIS 2413

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E   +G  +L V+AT          T+ +       A  +H   F ++   G +    
Sbjct: 2414 ISELTRVGMEILTVNAT-------GHTTFDI-------AGGNHGDAFDVDAVQGVVKVKT 2459

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD E    Y L + A DG VP       V I++ D NDN PVF Q++YTA++ E    G
Sbjct: 2460 PLDYERYPNYTLIIGAYDGSVPPHVGYARVVITLQDENDNVPVFSQRVYTAHVPEGKSAG 2519

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             SV  V A+D D G+N  + Y L       G F +   +G++ T+  LDRE V ++ LK 
Sbjct: 2520 VSVLTVLASDEDSGVNAEVEYHL----VGSGPFQVSRTTGLVTTSDVLDRELVGSYTLKV 2575

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A + G    +S  IVH+ + DIND+PP  +   LT  +SE +  G  + ++   D DE 
Sbjct: 2576 RAENPGNRSMASEAIVHVTVTDINDTPPTLQQP-LTASVSEQAQAGDLVLQLHGDDKDEP 2634

Query: 718  PNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLW 775
             N+ +HY  +  G+    F++    G+     +T+V +LD E+ +  Y L +        
Sbjct: 2635 VNSPLHYGFLPNGNPGGVFAIGALSGN-----ITLVKNLDRET-KSLYSLEVFVNDSLHV 2688

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833
                V++ VTD+NDN P       +    +D         V A DAD     +L Y  L 
Sbjct: 2689 TQATVKVTVTDINDNPPKFLLLPYVTQLPEDSAVGVTVMNVTAVDADEGTNVELNYEFLL 2748

Query: 834  GNNANLILLNETTGSMTLS 852
                + + ++  TG +TL+
Sbjct: 2749 SPYGSFLAVDARTGMITLN 2767



 Score =  344 bits (846), Expect = 5e-94
 Identities = 270/877 (30%), Positives = 413/877 (47%), Gaps = 69/877 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VL+  D+ PVF  + Y  +V E    GT V  + AT +D  KN  + Y I  V+ D  
Sbjct: 619  VTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKD--KNGSISYAI--VSGDPT 674

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                 +F +D   G +     +DRE+ A+Y + V A  +   V   L
Sbjct: 675  N-----------------LFLVDSTGGIIKINGDMDREEKAQYLLAVIA--RVGTVKP-L 714

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+ AT+++ ++D NDN PQFS  T +V VD D +     V+    A D D G N  +RY 
Sbjct: 715  SAQATVNIEVLDRNDNAPQFS--TSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQ 772

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   N +    I+S SG + L + L       Y + + A D GSP + +T  + I +  +
Sbjct: 773  LT-SNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL-SI 830

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            N + P+F  S +   V  + P+ Y    V A D D G N +L Y++      GN +    
Sbjct: 831  N-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ----GNEEGLFG 885

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I P  G +Y    L +  +  Y L+V ATDGG P  SA+                F+   
Sbjct: 886  IFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNT 944

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            +   +AE+  PGT V TL A   D         +  ++   F++  ++G+  IT    LD
Sbjct: 945  FRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQ--ITTRVRLD 1002

Query: 431  FKQ------ERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             ++         Y++   A   D+  + D A+V + +TD N+ APVF  A Y  +V E +
Sbjct: 1003 REELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELS 1062

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
              G+ V  + A D+D G NA+  YSL S    +       +F IN  TG +  +K LDRE
Sbjct: 1063 LPGSPVFRIKAMDADKGDNAKFFYSLVSGTGMD-------KFFINSSTGELHLSKTLDRE 1115

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            T S Y L V A D    +L  T  +EI+V D ND  PVF +  YT NI EDAL+G+ V  
Sbjct: 1116 TTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVIN 1175

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            + A+D D+G NG I Y +         F ++ A+G +   K+LD E+   ++L   A D 
Sbjct: 1176 LNASDKDIGQNGLIKYSIS-NGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDH 1234

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G  P SSTV V + + D+ND+ P+F +  +T  + EN   G  +G   A D D G NA +
Sbjct: 1235 GLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHI 1294

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE---SPRKKYELVIRA---ASPPLWN 776
             +S+     S +FS+     S   E+ T+  +D E   + R  ++LV+ A    SP L  
Sbjct: 1295 AFSMYSQTPSKTFSV----NSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLST 1350

Query: 777  DVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835
               + + VTD NDN+P  +        +  +   +         D +   K+ Y I+SGN
Sbjct: 1351 RKSITVQVTDENDNSPGFVSPPAAAAGSSLNVMTI----TAEDPDRNSNGKVTYSIISGN 1406

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            N     L+ +TG + +  Q+  N P +  + +  +DG
Sbjct: 1407 N-GYFNLHPSTGQLQMIHQIPDN-PTIYQLTIQASDG 1441



 Score =  340 bits (835), Expect = 1e-92
 Identities = 272/877 (31%), Positives = 407/877 (46%), Gaps = 68/877 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND++PVF    Y  +V E +  G+ V  +KA D D G NA+  Y++   T    
Sbjct: 1037 VTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADKGDNAKFFYSLVSGTG--- 1093

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             D F I+  +G L    +LDRE  + Y ++VKATD ++     L
Sbjct: 1094 ----------------MDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNA---NL 1134

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             STA I + + D ND  P F E  YTV++ ED  +    ++  + A+D D+G N  I+Y+
Sbjct: 1135 YSTAKIEITVGDSNDQRPVFPESDYTVNITEDALI--GSLVINLNASDKDIGQNGLIKYS 1192

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN    F ++S +G + + K+LD+E  + Y L I AQD G    S+T  + +N+ DV
Sbjct: 1193 ISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDV 1252

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDNAP F T     +V ENV  G+ + R  A D D G NA + ++M    Y+       +
Sbjct: 1253 NDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSM----YSQTPSKTFS 1308

Query: 311  IDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
            ++  +  + T   +D ET    +  +QL+V ATD G P  S   +              F
Sbjct: 1309 VNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGF 1368

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLIT 424
            +        A        V+T+TA D D ++  ++ Y I  GN  G F++    G+ L  
Sbjct: 1369 VSPP-----AAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGN-NGYFNLHPSTGQ-LQM 1421

Query: 425  VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            + Q  D      Y LT+ A+D G   R    +V +         P F +A Y  SV E+ 
Sbjct: 1422 IHQIPD--NPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENK 1479

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
              GT+V+ V A      +N  I Y L+S+ S          F +   TG + T + +DRE
Sbjct: 1480 VAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGG-------FEVVKSTGVVKTTRGIDRE 1532

Query: 543  TM-SGYLLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             M + + L V A D   PS  + +  V I+V DVNDN PVF    +T +I E+   GT+V
Sbjct: 1533 GMGASFNLVVYAVDKQGPSARTSSATVTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTV 1592

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              V ATD D G N ++ Y           F ID +SG I T    DRE+   + +   A 
Sbjct: 1593 ITVTATDPDAGDNAKVSY-ATYGGSHGNKFAIDASSGRIYTTGTFDRETKDDYSINVTAS 1651

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G P +SST +V + + D ND+ P F +    F I+E++ +G +IG + A D D G NA
Sbjct: 1652 DHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENA 1711

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN---- 776
             + YSI   + + +FS+    G    E+     LD E   + Y L + A      N    
Sbjct: 1712 RLTYSIVSPEKA-TFSMNPVTG----EITVGQRLDREGV-EHYLLNVTATDNGRLNTNDA 1765

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSG 834
             V V I V DVNDNAP  +         +    + P   V A D D      ++Y ++SG
Sbjct: 1766 SVDVYINVLDVNDNAPQFEAAVYHGEISESADKLTPIVTVKAIDKDSGSNGIVKYSLISG 1825

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            N+ +   +    G++  +  L+        +EV   D
Sbjct: 1826 NDGDAFTI-LGNGTIVNAEVLDREKKSTYNLEVRAVD 1861



 Score =  338 bits (832), Expect = 3e-92
 Identities = 265/888 (29%), Positives = 425/888 (47%), Gaps = 70/888 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            INV D ND  P F      A V E +  G  VLT+ A D D G N +V Y++ L   D  
Sbjct: 1876 INVTDVNDQPPEFTSASV-AHVSENSRVGDVVLTVIAVDADEGSNGDVVYSLGL---DIG 1931

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                 F +  + G L    S+DREK A Y++ V ATD  +P    L
Sbjct: 1932 AP-----------------FSLGSKDGVLRVSGSMDREKKANYSIRVTATDLGTPP---L 1971

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S++  I V + D ND+ P F     TV +DE+ S      I  ++A D D G N+ IRYA
Sbjct: 1972 SASMEITVIVDDYNDHRPVFLSHIGTVFIDENAS--PGTEIITLQAVDGDSGVNAEIRYA 2029

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
             + GN+   F+I+S++G +   + LD E    + L + A D G P + + T + + +RDV
Sbjct: 2030 FVTGNSNNSFTINSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDV 2089

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  S +   VSE V +  +IV V A D D G +  +TY +T     G       
Sbjct: 2090 NDNQPVFTMSEYAAEVSEGV-VESNIVTVVAEDRDIGSDGSVTYCITQ----GREGGLFV 2144

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G +  + +LDRET++KY L V ATDGG P  S+ A               F P  
Sbjct: 2145 INENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPAT 2204

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
              V++ ED   GT V+ ++A D D  +      +   +  RFSI S+ G  +IT  +PLD
Sbjct: 2205 LTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSLKYSFSRFSIDSKTG--VITTVRPLD 2262

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTV 488
             +   ++ L V A+D+G       + ++I   D N++ P F+ + + A++ + AP+GT V
Sbjct: 2263 REIAGQHKLEVLASDAGKPPLQGKLDLDIIVGDKNDHDPEFQQSQFQATISQSAPVGTIV 2322

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
             V+SA D D G NA+  YS++S   N+A       F +N ++G I+ ++ +   + + Y 
Sbjct: 2323 FVLSARDEDTGENAESDYSITS--GNDASV-----FSLNARSGVISVSRTVP-SSPAQYS 2374

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L + A +   P  +D+  ++I+V     +  VF + L+     + ++  + +++VG    
Sbjct: 2375 LKIKAANRNAPGRTDSATLQITV-----SSAVFPRFLHP----DQSISISELTRVGMEIL 2425

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
             V   G   +++   +  + +F +D   GV++    LD E    + L   A DG  PP  
Sbjct: 2426 TVNATGHTTFDIAGGNHGD-AFDVDAVQGVVKVKTPLDYERYPNYTLIIGAYDGSVPPHV 2484

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
                V I ++D ND+ PVF     T ++ E    G ++  + A D D G NA V Y + G
Sbjct: 2485 GYARVVITLQDENDNVPVFSQRVYTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEYHLVG 2544

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVT 785
               S  F +    G     LVT  D+        Y L +RA +P    + ++  V + VT
Sbjct: 2545 ---SGPFQVSRTTG-----LVTTSDVLDRELVGSYTLKVRAENPGNRSMASEAIVHVTVT 2596

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTDKLQYRIL-SGNNANLIL 841
            D+ND  P ++  Q +  +  +    G    ++   D D  V   L Y  L +GN   +  
Sbjct: 2597 DINDTPPTLQ--QPLTASVSEQAQAGDLVLQLHGDDKDEPVNSPLHYGFLPNGNPGGVFA 2654

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
            +   +G++TL   L+     L ++EV V D ++  +A ++++V  I +
Sbjct: 2655 IGALSGNITLVKNLDRETKSLYSLEVFVNDSLHVTQATVKVTVTDIND 2702



 Score =  334 bits (821), Expect = 6e-91
 Identities = 261/887 (29%), Positives = 419/887 (47%), Gaps = 70/887 (7%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            SVP  I+ Q    D NDH  +F    +  +V E +S GT V TL A   D  +  ++ Y+
Sbjct: 923  SVPVTIYIQ----DSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYS 978

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVK 118
              L+++++                    F +D RSG + TR  LDRE++ + T   V + 
Sbjct: 979  --LISSESH-------------------FAVDVRSGQITTRVRLDREELIKNTGSNVYIM 1017

Query: 119  ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
              +     +      A + V + D NDN P FS   Y ++V E +S+  +PV  +IKA D
Sbjct: 1018 QAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSE-LSLPGSPVF-RIKAMD 1075

Query: 179  ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
            AD G N+   Y+++ G    +F I+S +G++ L KTLD E   SY LV++A D  + +  
Sbjct: 1076 ADKGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLY 1135

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            +T ++ I + D ND  P F  S +  +++E+  IG  ++ + A D D G N  + Y++++
Sbjct: 1136 STAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISN 1195

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                GN+     ++  +G +  +  LD ET   Y+L +TA D G  P S+T         
Sbjct: 1196 ----GNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLD 1251

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS 416
                   F      + + E+   G PV   TA+D D     H  + +        FS+ S
Sbjct: 1252 VNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNS 1311

Query: 417  QNGRGLITVAQPLDFKQERR--YVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA 472
                     A  L+     R  + L V ATD G    S    + + +TD N+ +P F + 
Sbjct: 1312 ATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSP 1371

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            P  A     A     V+ ++A D D   N ++TYS+        ++ ++  F ++P TG 
Sbjct: 1372 PAAA-----AGSSLNVMTITAEDPDRNSNGKVTYSI--------ISGNNGYFNLHPSTGQ 1418

Query: 533  I-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +   +++ D  T+  Y LT+ A DGG PS    T V +         P F    Y  ++ 
Sbjct: 1419 LQMIHQIPDNPTI--YQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVT 1476

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV- 650
            E+ + GTSV  V A      LNG I Y L   D  +G F +  ++GV++T + +DRE + 
Sbjct: 1477 ENKVAGTSVVTVLAAYPQSSLNGNIEYYL-TSDSSKGGFEVVKSTGVVKTTRGIDREGMG 1535

Query: 651  ATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            A+ +L   A+D  G   ++S+  V I ++D+ND+ PVF SD  T  I+EN   GTT+  +
Sbjct: 1536 ASFNLVVYAVDKQGPSARTSSATVTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITV 1595

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             A DPD G NA V Y+  GG   N F+++   G     + T    D E+ +  Y + + A
Sbjct: 1596 TATDPDAGDNAKVSYATYGGSHGNKFAIDASSG----RIYTTGTFDRET-KDDYSINVTA 1650

Query: 770  A---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD- 825
            +   +P   +   V + V D NDN+P       +F+  +D       G V A DAD+ + 
Sbjct: 1651 SDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGEN 1710

Query: 826  -KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             +L Y I+S   A    +N  TG +T+  +L+    +   + V+ TD
Sbjct: 1711 ARLTYSIVSPEKAT-FSMNPVTGEITVGQRLDREGVEHYLLNVTATD 1756



 Score =  332 bits (816), Expect = 2e-90
 Identities = 274/875 (31%), Positives = 411/875 (46%), Gaps = 68/875 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+SP F      A     A S   V+T+ A D D   N +V Y+I       +
Sbjct: 1356 VQVTDENDNSPGFVSPPAAA-----AGSSLNVMTITAEDPDRNSNGKVTYSI-------I 1403

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +  +           +Q + +I             D   +  Y + ++A+D   P     
Sbjct: 1404 SGNNGYFNLHPSTGQLQMIHQIP------------DNPTI--YQLTIQASDGGQPSRQTQ 1449

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +  +      I      P FS   Y  SV E+  V    V+  + A       N  I Y 
Sbjct: 1450 TVVSVFKEGPIGGG---PTFSSADYQGSVTEN-KVAGTSVVTVLAAYPQS-SLNGNIEYY 1504

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPS-RSNTTQLLINIR 248
            +   +++  F +   +G V   + +D E +  S+ LV+ A D   PS R+++  + I ++
Sbjct: 1505 LTSDSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQ 1564

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDNAP F +  F  S++ENV  G +++ V A D D G NA+++Y      Y G+    
Sbjct: 1565 DVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSYAT----YGGSHGNK 1620

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              ID  SG +YT+G  DRET+  Y + VTA+D G+P +S+T                F  
Sbjct: 1621 FAIDASSGRIYTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPA 1680

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y  ++AED   G  + T++A+DAD  E+ RL Y I     +  FS+    G   ITV 
Sbjct: 1681 LHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVSPE-KATFSMNPVTGE--ITVG 1737

Query: 427  QPLDFKQERRYVLTVSATDSG--GRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAP 483
            Q LD +    Y+L V+ATD+G    +D ++ V IN+ D N+ AP FE A Y   + E A 
Sbjct: 1738 QRLDREGVEHYLLNVTATDNGRLNTNDASVDVYINVLDVNDNAPQFEAAVYHGEISESAD 1797

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
              T ++ V A D D G N  + YSL S    +A       F I    G I   ++LDRE 
Sbjct: 1798 KLTPIVTVKAIDKDSGSNGIVKYSLISGNDGDA-------FTILGN-GTIVNAEVLDREK 1849

Query: 544  MSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             S Y L V A D      L   T V I+V DVND  P F      A++ E++ VG  V  
Sbjct: 1850 KSTYNLEVRAVDQATSGGLEGVTRVVINVTDVNDQPPEFTSAS-VAHVSENSRVGDVVLT 1908

Query: 603  VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A DAD G NG + Y L     + G+ F +    GV+R + ++DRE  A + ++  A D
Sbjct: 1909 VIAVDADEGSNGDVVYSLG---LDIGAPFSLGSKDGVLRVSGSMDREKKANYSIRVTATD 1965

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             GTPP S+++ + + ++D ND  PVF S   T +I EN+  GT I  ++A D D G NA 
Sbjct: 1966 LGTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAE 2025

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDV-R 779
            + Y+   G+ +NSF++ +  G     L T  +LD E+ PR   E++      P  + V  
Sbjct: 2026 IRYAFVTGNSNNSFTINSITG----RLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTN 2081

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNA 837
            V +++ DVNDN PV    +       +         V A D D+     + Y I  G   
Sbjct: 2082 VTVVLRDVNDNQPVFTMSEYAAE-VSEGVVESNIVTVVAEDRDIGSDGSVTYCITQGREG 2140

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             L ++NE TG++ ++ +L+       T+ V  TDG
Sbjct: 2141 GLFVINENTGTIGITAKLDRETKSKYTLRVQATDG 2175



 Score =  318 bits (780), Expect = 5e-86
 Identities = 265/885 (29%), Positives = 400/885 (45%), Gaps = 75/885 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ PVF  + Y A V EG S+G +VLT+ A+D+D G NAEVEY   LV +   
Sbjct: 2491 ITLQDENDNVPVFSQRVYTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEY--HLVGSGP- 2547

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F++   +G + T   LDRE V  YT+ V+A +   P +  +
Sbjct: 2548 -------------------FQVSRTTGLVTTSDVLDRELVGSYTLKVRAEN---PGNRSM 2585

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +S A +HV + D ND  P   ++  T SV E     D  ++ ++   D D   NS + Y 
Sbjct: 2586 ASEAIVHVTVTDINDTPPTL-QQPLTASVSEQAQAGD--LVLQLHGDDKDEPVNSPLHYG 2642

Query: 191  II-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +  GN    F+I +LSG+++LVK LD E    Y L +   D    +++      + + D
Sbjct: 2643 FLPNGNPGGVFAIGALSGNITLVKNLDRETKSLYSLEVFVNDSLHVTQATVK---VTVTD 2699

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P+F    +   + E+  +G +++ V A DADEG N EL Y      Y G+    +
Sbjct: 2700 INDNPPKFLLLPYVTQLPEDSAVGVTVMNVTAVDADEGTNVELNYEFLLSPY-GSF---L 2755

Query: 310  TIDPRSGWVYTSGQLDRETQAK------YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
             +D R+G +  +  +  +  +       Y L V A +   P   A A             
Sbjct: 2756 AVDARTGMITLNRAIAFKPFSALPNPNIYNLTVRARNIYPPHYKADAAIQIEVLDTNDHA 2815

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL-HYEITGGNTRGRFSITSQNGR 420
              F+   Y +   +D   G  +  + A D  +   N L  YE   GN  GRF +  + G 
Sbjct: 2816 PVFVKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPETGE 2875

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASV 478
             LI  A  L     + Y + V A+D G    SDTA V + +T+ N + PVF  A Y  S 
Sbjct: 2876 VLI--ASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSE 2933

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             ED  +G+ +L V+ATD D G N +I+Y + +  S E        F I    G++  +K 
Sbjct: 2934 NEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQE-------YFGIGLTNGSLYVSKP 2986

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV-G 597
            LD E    Y L V+A DGG    +    V I++ DVNDN PVF    Y   + E+     
Sbjct: 2987 LDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTPRS 3046

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              V  V ATD D      + Y +     ++  FVID  +G IR     D E   +  L  
Sbjct: 3047 VVVCSVRATDRDERGQQSVRYSILGGSGKD-KFVIDERTGEIRATVEFDFEVTMSSFLMI 3105

Query: 658  VAIDGGTPPQSST---VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
             A D G  PQ +      VHI I  +N+  PVF     T  ++EN+PIG ++  + A D 
Sbjct: 3106 AAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDK 3165

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI------R 768
            D+GP+ VV Y + G D+   F L++  G+    L    DLD E        VI       
Sbjct: 3166 DKGPDGVVLYHLLGSDNQQGFDLDSNTGT----LSVSGDLDNERAGIVTLRVIAKNLFQN 3221

Query: 769  AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK- 826
            + +P       + + VTD ND    +K   +   +  +   +G     V A D D   + 
Sbjct: 3222 SVTPSSVAHATIVVTVTDANDPPRFLK--SVYSAHVTEGSRIGHVVTNVTAVDDDSDIRS 3279

Query: 827  LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            ++Y I +GN  N  +++  TG +  + +L+        + V+ TD
Sbjct: 3280 IRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATD 3324



 Score =  295 bits (723), Expect = 4e-79
 Identities = 242/877 (27%), Positives = 396/877 (45%), Gaps = 74/877 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D NDH P F+  Q++A++ + A  GT V  L A D+D G+NAE +Y+I        
Sbjct: 2291 IIVGDKNDHDPEFQQSQFQATISQSAPVGTIVFVLSARDEDTGENAESDYSIT------- 2343

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +  DA             VF ++ RSG +    ++     A+Y++ +KA ++ +P     
Sbjct: 2344 SGNDAS------------VFSLNARSGVISVSRTVPSSP-AQYSLKIKAANRNAPGR--- 2387

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + +AT+ + +   +  +P+F     ++S+ E         + ++      V A     + 
Sbjct: 2388 TDSATLQITV--SSAVFPRFLHPDQSISISE---------LTRVGMEILTVNATGHTTFD 2436

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I GGN    F +D++ G V +   LDYE+  +Y L+I A DG  P      +++I ++D 
Sbjct: 2437 IAGGNHGDAFDVDAVQGVVKVKTPLDYERYPNYTLIIGAYDGSVPPHVGYARVVITLQDE 2496

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F   ++   V E    G S++ V A D D GVNAE+ Y +           P  
Sbjct: 2497 NDNVPVFSQRVYTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEYHLVGSG-------PFQ 2549

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +   +G V TS  LDRE    Y L V A + G+   ++ A                +   
Sbjct: 2550 VSRTTGLVTTSDVLDRELVGSYTLKVRAENPGNRSMASEAIVHVTVTDINDTPPT-LQQP 2608

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYE-ITGGNTRGRFSITSQNGRGLITVAQ 427
                ++E    G  V+ L   D DE  ++ LHY  +  GN  G F+I + +G   IT+ +
Sbjct: 2609 LTASVSEQAQAGDLVLQLHGDDKDEPVNSPLHYGFLPNGNPGGVFAIGALSGN--ITLVK 2666

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
             LD + +  Y L V   DS      A V++ +TD N+  P F   PY   + ED+ +G T
Sbjct: 2667 NLDRETKSLYSLEVFVNDS-LHVTQATVKVTVTDINDNPPKFLLLPYVTQLPEDSAVGVT 2725

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG- 546
            V+ V+A D+D G N ++ Y          ++ +     ++ +TG IT N+ +  +  S  
Sbjct: 2726 VMNVTAVDADEGTNVELNYEF-------LLSPYGSFLAVDARTGMITLNRAIAFKPFSAL 2778

Query: 547  -----YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
                 Y LTV AR+   P       ++I V+D ND+ PVF + +Y    ++DA  G S+ 
Sbjct: 2779 PNPNIYNLTVRARNIYPPHYKADAAIQIEVLDTNDHAPVFVKSVYLLFAVQDAGSGVSIG 2838

Query: 602  QVGATDA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            +V A D  D G N  + YE        G F + P +G +    +L  +   T+ ++  A 
Sbjct: 2839 RVEAVDKFDYGPNALVRYEA-ISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRAS 2897

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G P  S T  V++++ + N  PPVF         +E+  +G+ +  + A D D G N 
Sbjct: 2898 DMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNG 2957

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777
             + Y I  G+    F +    GS    L     LDYE  ++ Y L + A      P  + 
Sbjct: 2958 EISYDIIAGNSQEYFGIGLTNGS----LYVSKPLDYEH-QENYSLNVSATDGGKEPKTSY 3012

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSG 834
              V I + DVNDN PV    +      ++  P       V A D D      ++Y IL G
Sbjct: 3013 ATVRITLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGG 3072

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +  +  +++E TG +  + + +  V   + + ++  D
Sbjct: 3073 SGKDKFVIDERTGEIRATVEFDFEVTMSSFLMIAAKD 3109



 Score =  285 bits (700), Expect = 3e-76
 Identities = 251/887 (28%), Positives = 390/887 (43%), Gaps = 85/887 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD NDH+PVF        V+E   SGTTV+ + A D D+G NA+V Y+++   +   
Sbjct: 2188 VNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSLKYSFSR-- 2245

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ID ++G + T   LDRE   ++ + V A+D   P    L
Sbjct: 2246 -------------------FSIDSKTGVITTVRPLDREIAGQHKLEVLASDAGKPP---L 2283

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + + + D ND+ P+F +  +  ++ +   V    ++  + A D D G N+   Y+
Sbjct: 2284 QGKLDLDIIVGDKNDHDPEFQQSQFQATISQSAPV--GTIVFVLSARDEDTGENAESDYS 2341

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN    FS+++ SG +S+ +T+     + Y L I+A +  +P R+++  L I +   
Sbjct: 2342 ITSGNDASVFSLNARSGVISVSRTVPSSPAQ-YSLKIKAANRNAPGRTDSATLQITVSSA 2400

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
                PRF       S+SE   +G  I+ V A           T+ +      GN      
Sbjct: 2401 V--FPRFLHPDQSISISELTRVGMEILTVNA-------TGHTTFDIAG----GNHGDAFD 2447

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +D   G V     LD E    Y L++ A DG  PP    A               F    
Sbjct: 2448 VDAVQGVVKVKTPLDYERYPNYTLIIGAYDGSVPPHVGYARVVITLQDENDNVPVFSQRV 2507

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y   + E +  G  V+T+ A+D D   +  + Y + G    G F ++   G  L+T +  
Sbjct: 2508 YTAHVPEGKSAGVSVLTVLASDEDSGVNAEVEYHLVGS---GPFQVSRTTG--LVTTSDV 2562

Query: 429  LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    Y L V A + G RS    A+V + +TD N+  P  +  P TASV E A  G 
Sbjct: 2563 LDRELVGSYTLKVRAENPGNRSMASEAIVHVTVTDINDTPPTLQQ-PLTASVSEQAQAGD 2621

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             VL +   D D  +N+ + Y      +   V      F I   +G IT  K LDRET S 
Sbjct: 2622 LVLQLHGDDKDEPVNSPLHYGFLPNGNPGGV------FAIGALSGNITLVKNLDRETKSL 2675

Query: 547  YLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            Y L V   D    SL  T   V+++V D+NDN P F    Y   + ED+ VG +V  V A
Sbjct: 2676 YSLEVFVND----SLHVTQATVKVTVTDINDNPPKFLLLPYVTQLPEDSAVGVTVMNVTA 2731

Query: 606  TDADVGLNGRIHYE--LDPKDREEGSFV-IDPASGVIRTNKALDRESVAT------HDLK 656
             DAD G N  ++YE  L P     GSF+ +D  +G+I  N+A+  +  +       ++L 
Sbjct: 2732 VDADEGTNVELNYEFLLSPY----GSFLAVDARTGMITLNRAIAFKPFSALPNPNIYNLT 2787

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP-D 715
              A +   P   +   + I++ D ND  PVF       +  +++  G +IG + A D  D
Sbjct: 2788 VRARNIYPPHYKADAAIQIEVLDTNDHAPVFVKSVYLLFAVQDAGSGVSIGRVEAVDKFD 2847

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772
             GPNA+V Y    G+ +  F +    G      V +     +   K Y + +RA+    P
Sbjct: 2848 YGPNALVRYEAISGNGTGRFRVAPETGE-----VLIASSLRDDVNKTYYIRVRASDMGQP 2902

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYR 830
             + +   V + VT+ N + PV        +  +D         V A D D     ++ Y 
Sbjct: 2903 KMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYD 2962

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877
            I++GN+     +  T GS+ +S  L+    +  ++ VS TDG  E K
Sbjct: 2963 IIAGNSQEYFGIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPK 3009



 Score =  279 bits (684), Expect = 2e-74
 Identities = 238/839 (28%), Positives = 381/839 (45%), Gaps = 58/839 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID  +G + T ASLD E    +++++ A D  +  +   + TA ++V +++  DN P 
Sbjct: 574  FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYA---AKTAVVNVTVLNKADNLPV 630

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            F  + Y  +V E  +V    ++ ++ AT  D   N +I YAI+ G+    F +DS  G +
Sbjct: 631  FLYEMYNFTVYE--NVPKGTLVGRVYATTKD--KNGSISYAIVSGDPTNLFLVDSTGGII 686

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
             +   +D E+   Y L + A+ G     S    + I + D NDNAP+F TS     +   
Sbjct: 687  KINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGT 746

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
              +G  +    A D D G N  + Y +     T N +  + I+  SG +  + +L    +
Sbjct: 747  WLVGQVVYNAAAVDLDAGKNGLVRYQL-----TSNAEGLLWINSTSGVIKLARKLTDGDE 801

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
             +Y + V A+D G PP+ +T T              F    Y   +   +P       + 
Sbjct: 802  TQYTVQVLASDSGSPPQHSTMT--IHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVV 859

Query: 390  ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            A D D  ++ +L Y I  GN  G F I      G + + + L    +  Y L V ATD G
Sbjct: 860  AVDQDSGKNGQLFYSIPQGNEEGLFGIFP---GGKLYIRKSLLQALKGSYDLIVRATDGG 916

Query: 448  GRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
              S +A V +   I D+N++  +F N  +  +V E++  GT V  + A   D      I 
Sbjct: 917  VPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIV 976

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM------SGYLLTVTARDGGVP 559
            YSL   IS+E+       F ++ ++G ITT   LDRE +      + Y++   A      
Sbjct: 977  YSL---ISSES------HFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTT 1027

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
               D   V ++V D+NDN PVF + +Y   + E +L G+ V ++ A DAD G N +  Y 
Sbjct: 1028 IKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADKGDNAKFFYS 1087

Query: 620  LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
            L         F I+ ++G +  +K LDRE+ ++++L   A D       ST  + I + D
Sbjct: 1088 L-VSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGD 1146

Query: 680  INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739
             ND  PVF     T  I+E++ IG+ +  + A D D G N ++ YSI  G+ +  F +E+
Sbjct: 1147 SNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVES 1206

Query: 740  RQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVTDVNDNAPVMKD 796
              G     L+    LD+E+  + YEL I A      PL + V V + V DVNDNAP+   
Sbjct: 1207 ATG----RLIVAKSLDFET-TQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPT 1261

Query: 797  FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
              +     ++     P GR  A D D      + + + S   +    +N  T  +T    
Sbjct: 1262 QPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAA 1321

Query: 855  LNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDM--TAEQFLSP 911
            ++     L TM          + A  Q S +L T +    SITV++ D    +  F+SP
Sbjct: 1322 ID-----LETMPAGRDSFQLVVMATDQGSPKLSTRK----SITVQVTDENDNSPGFVSP 1371



 Score =  250 bits (613), Expect = 9e-66
 Identities = 212/754 (28%), Positives = 338/754 (44%), Gaps = 40/754 (5%)

Query: 149  QFSEKTYTVSV-DEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            Q S  T T++  D   +         +   D +      ++ +  GGN    FSIDS +G
Sbjct: 522  QVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGGNNNGNFSIDSSTG 581

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             +S + +LD+E    + L+I A+DGG+   + T  + + + +  DN P F   ++  +V 
Sbjct: 582  VISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVY 641

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            ENVP G  + RV A   D+  N  ++Y +   D T N+ L   +D   G +  +G +DRE
Sbjct: 642  ENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPT-NLFL---VDSTGGIIKINGDMDRE 695

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
             +A+Y L V A  G   P SA AT              F      V++      G  V  
Sbjct: 696  EKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYN 755

Query: 388  LTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
              A D D  ++  + Y++T  N  G   I S +  G+I +A+ L    E +Y + V A+D
Sbjct: 756  AAAVDLDAGKNGLVRYQLT-SNAEGLLWINSTS--GVIKLARKLTDGDETQYTVQVLASD 812

Query: 446  SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
            SG     + + I+IT + N+ P F  + Y   V    P+      V A D D G N Q+ 
Sbjct: 813  SGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLF 872

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
            YS+     NE     +  F I P  G +   K L +     Y L V A DGGVPS S + 
Sbjct: 873  YSIPQ--GNE-----EGLFGIFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASV 924

Query: 566  DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
             V I + D ND+  +F    +   + E++  GT V  + A   D      I Y L     
Sbjct: 925  PVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSL---IS 981

Query: 626  EEGSFVIDPASGVIRTNKALDRESVA------THDLKAVAIDGGTPPQSSTVIVHIKIED 679
             E  F +D  SG I T   LDRE +        + ++A A+   T  +    IV + + D
Sbjct: 982  SESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTD 1041

Query: 680  INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739
            +ND+ PVF        +SE S  G+ +  I+A D D+G NA   YS+  G   + F + +
Sbjct: 1042 LNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADKGDNAKFFYSLVSGTGMDKFFINS 1101

Query: 740  RQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKD 796
              G    EL     LD E+    Y LV++   A++  L++  ++EI V D ND  PV  +
Sbjct: 1102 STG----ELHLSKTLDRET-TSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPE 1156

Query: 797  FQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQ 854
                 N  +D         + A D D+     ++Y I +GN A +  +   TG + ++  
Sbjct: 1157 SDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKS 1216

Query: 855  LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
            L+    +L  + ++  D G+  + + + ++V ++
Sbjct: 1217 LDFETTQLYELTITAQDHGLIPLSSTVNVTVNVL 1250



 Score =  215 bits (524), Expect = 6e-55
 Identities = 160/516 (31%), Positives = 256/516 (49%), Gaps = 41/516 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-PVSDRLSSTATIHVNIIDDNDNYP 148
           F  +  +G + T A +DRE   + ++ ++  + ++ P+S        + V + D NDN P
Sbjct: 72  FGFNSNTGVISTTARIDRETTTQISLQLRTLNPSNQPIS--------VQVQVDDINDNEP 123

Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS- 206
           +F    YT+ + E + V T NP+     ATD D G N  + Y I  G+    FS+ + + 
Sbjct: 124 RFPTLYYTLRIRESMDVNTTNPINT---ATDPDAGNNGTVDYTIASGDNTATFSLGTTAC 180

Query: 207 --GDVSLV---KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
             G    V   K LD E    Y+L I A D G+P+      + I I D ND+AP F  + 
Sbjct: 181 PTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNS 240

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           +  S++EN   G SI+RV A D D G N ++ Y + D D   +  +   +D  +G + T 
Sbjct: 241 YLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI-DWDAIQSNSI-FDLDSSTGVIRTK 298

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----XXFMP---GQYEVE 374
             LD E +  Y   V A+DGG P ++  AT                  ++P   G   + 
Sbjct: 299 QNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIR 358

Query: 375 LAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
            +E+    T +  +  TD D   +++   +IT G+  G F +    G   I + +PLD +
Sbjct: 359 -SENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFL-GFYFIQLQKPLDRE 416

Query: 433 QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
               Y LT++ TD G   RS    V I++TD N+ +P F +  YTA++ E A  G+ VL 
Sbjct: 417 LVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQ 476

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           ++ATD D G N  ++YS++    N+        F ++ Q+G +TT K LDRE +S   +T
Sbjct: 477 LNATDPDEGDNGTVSYSITG--GNDL-----GWFQVDFQSGLVTTAKPLDREQVSSVTIT 529

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           +TA+D G    + +T V ++++D NDN+P F +  Y
Sbjct: 530 ITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSY 565



 Score =  208 bits (507), Expect = 6e-53
 Identities = 155/501 (30%), Positives = 224/501 (44%), Gaps = 23/501 (4%)

Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
           QF  +S +G +S    +D E      L +R  +   PS +    + + + D+NDN PRF 
Sbjct: 71  QFGFNSNTGVISTTARIDRETTTQISLQLRTLN---PS-NQPISVQVQVDDINDNEPRFP 126

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW- 317
           T  +   + E++ +  +     A D D G N  + YT+   D T    L  T  P     
Sbjct: 127 TLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTL 186

Query: 318 -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            V T   LDRET   YQL +TATD G P                     F    Y   +A
Sbjct: 187 CVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIA 246

Query: 377 EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           E+  PG  ++ ++A D D  +   + Y I     +        +  G+I   Q LDF+ +
Sbjct: 247 ENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVK 306

Query: 435 RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA---PYT---ASVFEDAPIGT 486
             Y   V A+D G   ++D A V IN+ D N+ +P  +     P+    A   E++ I T
Sbjct: 307 NSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINT 366

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +  +  TD D   N+Q    +++             F        I   K LDRE +  
Sbjct: 367 NIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYF------IQLQKPLDRELVPF 420

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y LT+   D GVPS S    V I V DVNDN P F    YTANI E A  G+ V Q+ AT
Sbjct: 421 YNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNAT 480

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D G NG + Y +   + + G F +D  SG++ T K LDRE V++  +   A D G+ P
Sbjct: 481 DPDEGDNGTVSYSITGGN-DLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAP 539

Query: 667 QSSTVIVHIKIEDINDSPPVF 687
           ++ +  V + I D ND+ P F
Sbjct: 540 KTGSTTVTVTIIDGNDNKPRF 560



 Score =  199 bits (485), Expect = 3e-50
 Identities = 151/496 (30%), Positives = 227/496 (45%), Gaps = 33/496 (6%)

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
           +G + T+ ++DRET  +  L +   +  + P S                  +    Y + 
Sbjct: 78  TGVISTTARIDRETTTQISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLY----YTLR 133

Query: 375 LAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ---NGRGLITVAQ-P 428
           + E     T  P+ T T  DA  +  + Y I  G+    FS+ +     G  L  + + P
Sbjct: 134 IRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKP 193

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGT 486
           LD +    Y L ++ATD G  +      INIT  D N++APVF    Y  S+ E+   G 
Sbjct: 194 LDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGV 253

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           ++L VSA D D G N  I Y++  +         +  F ++  TG I T + LD E  + 
Sbjct: 254 SILRVSAADRDSGSNGDIKYAIDWD-----AIQSNSIFDLDSSTGVIRTKQNLDFEVKNS 308

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDALVGTSV 600
           Y   V A DGGVPS +D   V I+V+D NDN P  K           A   E++L+ T++
Sbjct: 309 YTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNI 368

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV-IRTNKALDRESVATHDLKAVA 659
           + +  TD D   N +   ++   D +EG F ++      I+  K LDRE V  ++L    
Sbjct: 369 AYILVTDKDSNTNSQTELKITNGD-DEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNV 427

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            D G P +S+   V I + D+ND+ P F S+  T  ISE +  G+ + ++ A DPDEG N
Sbjct: 428 TDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDN 487

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
             V YSI GG+D   F ++ + G     + T   LD E       + I A    S P   
Sbjct: 488 GTVSYSITGGNDLGWFQVDFQSGL----VTTAKPLDREQV-SSVTITITAQDHGSAPKTG 542

Query: 777 DVRVEILVTDVNDNAP 792
              V + + D NDN P
Sbjct: 543 STTVTVTIIDGNDNKP 558



 Score =  188 bits (459), Expect = 4e-47
 Identities = 143/480 (29%), Positives = 217/480 (45%), Gaps = 35/480 (7%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  Q+ V D ND+ P F    Y   +RE     TT     ATD D G N  V+YTI   +
Sbjct: 109 ISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTI--AS 166

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            D                 +       G +  ++T+  LDRE    Y + + ATD+ +P 
Sbjct: 167 GDN-----------TATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPA 215

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L     I++ I+D+ND+ P F++ +Y  S+ E  +      I ++ A D D G+N  
Sbjct: 216 ---LMGYCLINITILDENDHAPVFTQNSYLGSIAE--NTKPGVSILRVSAADRDSGSNGD 270

Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           I+YAI     Q    F +DS +G +   + LD+E   SY   + A DGG PS+++   + 
Sbjct: 271 IKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVT 330

Query: 245 INIRDVNDNAPRFYTSLF-----QESV-SENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           IN+ D NDN+P+   +        +++ SEN  I  +I  +   D D   N++    +T+
Sbjct: 331 INVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITN 390

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
            D  G   +         ++     LDRE    Y L +  TD G P RS           
Sbjct: 391 GDDEGCFKVEFL---GFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTD 447

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITS 416
                  F    Y   ++E    G+ V+ L ATD DE DN  + Y ITGGN  G F +  
Sbjct: 448 VNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDF 507

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474
           Q+  GL+T A+PLD +Q     +T++A D G   ++ +  V + I D N+  P F  + Y
Sbjct: 508 QS--GLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSY 565



 Score =  172 bits (418), Expect = 4e-42
 Identities = 147/512 (28%), Positives = 224/512 (43%), Gaps = 30/512 (5%)

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           Y   + E++PPGT V  +    A E          G+ + +F   S    G+I+    +D
Sbjct: 42  YTFHVQEEQPPGTYVGKVDGASAFE----------GSPK-QFGFNSNT--GVISTTARID 88

Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
             +E    +++        +    VQ+ + D N+  P F    YT  + E   + TT  +
Sbjct: 89  --RETTTQISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPI 146

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            +ATD D G N  + Y+++S   N A             T  + T K LDRET   Y L 
Sbjct: 147 NTATDPDAGNNGTVDYTIASG-DNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLN 205

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           +TA D G P+L     + I+++D ND+ PVF Q  Y  +I E+   G S+ +V A D D 
Sbjct: 206 ITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDS 265

Query: 611 GLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
           G NG I Y +D    +  S F +D ++GVIRT + LD E   ++    +A DGG P ++ 
Sbjct: 266 GSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKND 325

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFY------ISENSPIGTTIGEIRAHDPDEGPNAVVH 723
              V I + D ND+ P  +   L  +       SENS I T I  I   D D   N+   
Sbjct: 326 LATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTE 385

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR-VEI 782
             I  GDD   F +E   G    +L   +D +   P     L +     P  + +  V I
Sbjct: 386 LKITNGDDEGCFKVEF-LGFYFIQLQKPLDREL-VPFYNLTLNVTDKGVPSRSTLGFVLI 443

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQYRILSGNNANL 839
            VTDVNDN+P          N  +    G +  ++ A D D  D   + Y I  GN+   
Sbjct: 444 DVTDVNDNSPAFTS-NAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGW 502

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             ++  +G +T +  L+       T+ ++  D
Sbjct: 503 FQVDFQSGLVTTAKPLDREQVSSVTITITAQD 534



 Score =  167 bits (406), Expect = 1e-40
 Identities = 117/369 (31%), Positives = 177/369 (47%), Gaps = 33/369 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I +LD NDH+PVF    Y  S+ E    G ++L + A D+D G N +++Y I+       
Sbjct: 224 ITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDW------ 277

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              DA             +F +D  +G + T+ +LD E    YT  V A+D   P  + L
Sbjct: 278 ---DAIQS--------NSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDL 326

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD-----NPVIAKIKATDADVGANS 185
              AT+ +N++D NDN PQ  + TY    + D ++       N  IA I  TD D   NS
Sbjct: 327 ---ATVTINVLDTNDNSPQL-KITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNS 382

Query: 186 AIRYAIIGGNTQMQFSIDSLSGD-VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
                I  G+ +  F ++ L    + L K LD E V  Y L +   D G PSRS    +L
Sbjct: 383 QTELKITNGDDEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVL 442

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I++ DVNDN+P F ++ +  ++SE    G  ++++ A D DEG N  ++Y++     TG 
Sbjct: 443 IDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSI-----TGG 497

Query: 305 VDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            DL    +D +SG V T+  LDRE  +   + +TA D G  P++ + T            
Sbjct: 498 NDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNK 557

Query: 364 XXFMPGQYE 372
             FM   Y+
Sbjct: 558 PRFMKSSYK 566



 Score =  130 bits (313), Expect = 2e-29
 Identities = 105/339 (30%), Positives = 155/339 (45%), Gaps = 32/339 (9%)

Query: 4    PFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63
            P  +H  I +   N+  PVF    + A+V E A  G +VL + ATD+D G +  V Y   
Sbjct: 3121 PASVH--ILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKDKGPDGVVLY--H 3176

Query: 64   LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ- 122
            L+ +D                  Q  F +D  +G L     LD E+    T+ V A +  
Sbjct: 3177 LLGSDN-----------------QQGFDLDSNTGTLSVSGDLDNERAGIVTLRVIAKNLF 3219

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             + V+    + ATI V + D ND  P+F +  Y+  V E   +    V+  + A D D  
Sbjct: 3220 QNSVTPSSVAHATIVVTVTDANDP-PRFLKSVYSAHVTEGSRI--GHVVTNVTAVDDDSD 3276

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
              S IRY I  GNT   F +D+++G V     LD E +  YRL + A D G+P  +    
Sbjct: 3277 IRS-IRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATDNGTPPMTGNAT 3335

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDY 301
            L++ + D+NDN P          V+EN P G  ++ + A D D   N     Y+++  DY
Sbjct: 3336 LVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDLNPNRGPFKYSISGSDY 3395

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
             G+  L ++    SG V T   LDRE Q  Y + +  TD
Sbjct: 3396 -GSFRLNVS----SGVVSTVKSLDREKQDAYNISIKVTD 3429



 Score = 57.6 bits (133), Expect = 1e-07
 Identities = 51/183 (27%), Positives = 83/183 (45%), Gaps = 25/183 (13%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC C  G+TG NC+  +    C+     S C   S C    +       C  D      
Sbjct: 3758 YTCTCKPGYTGQNCDVDIN--YCQ----SSPCMYNSTC----KDLPTSFECVCDFGGRGE 3807

Query: 1102 VCELRARSFPVSSFLTFP---GLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLA 1156
             CE+ +  F  +S++ FP   G+ ++   ++ ++F+T + +GLL YN  G      DF+A
Sbjct: 3808 RCEISSFGFEPASYMLFPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIA 3867

Query: 1157 LELVSSEAGRGGGPGLRFSFSLG--GGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDD 1214
            LE+V           L FS++LG  G    I  +  V DG WH V +    +   +++D 
Sbjct: 3868 LEIVERY--------LWFSYNLGYTGIPEVIKSDRAVTDGKWHHVTVIRDKKKGELLVDG 3919

Query: 1215 CDK 1217
             +K
Sbjct: 3920 SNK 3922



 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 1282 VGCISDF--YIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339
            VG I DF  Y+      ++      G +  CP K S C+ +PC NG  C D W  Y C+C
Sbjct: 3943 VGGIKDFDAYLSDSRKHMHEAREKEGVMNRCPRK-SWCTWSPCDNGGTCVDTWLDYYCEC 4001

Query: 1340 KEGHTGKDC 1348
             +G +G++C
Sbjct: 4002 PDGFSGRNC 4010



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%)

Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568
            +S  DC  + C     C  +  S  C+C  G  G  C   +  C   PC  A    D TP
Sbjct: 3697 ESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLCESDIDECLTNPCKHASAC-DNTP 3755

Query: 1569 KGYSCACEPGYT 1580
             GY+C C+PGYT
Sbjct: 3756 GGYTCTCKPGYT 3767



 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 57/260 (21%), Positives = 99/260 (38%), Gaps = 31/260 (11%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369
            C    + C S+PC   + C DL  ++ C C  G  G+ C  S+     FG      F P 
Sbjct: 3771 CDVDINYCQSSPCMYNSTCKDLPTSFECVCDFGGRGERCEISS-----FG------FEPA 3819

Query: 1370 LRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETM----YLPMATLSDGAWHR 1425
               +  P L  ++ +T        S    +GLL Y+ +G       ++ +  +    W  
Sbjct: 3820 SYML-FPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIALEIVERYLWFS 3878

Query: 1426 IEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFE-- 1483
              + + G    +  D  +       +   I+ +  G++L+ G +   G +  D GF +  
Sbjct: 3879 YNLGYTGIPEVIKSDRAVTDGKWHHV-TVIRDKKKGELLVDGSNKKTGEV--DGGFTQLE 3935

Query: 1484 --------GCIQ--DVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWD 1533
                    G I+  D  +  ++  ++    +E V + C  ++ C  S C     CV +W 
Sbjct: 3936 LNQSPLLVGGIKDFDAYLSDSRKHMHEAREKEGVMNRCPRKSWCTWSPCDNGGTCVDTWL 3995

Query: 1534 SSTCTCEAGRVGPQCVSACE 1553
               C C  G  G  C  A E
Sbjct: 3996 DYYCECPDGFSGRNCEKAME 4015



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 28/207 (13%)

Query: 1390 AFV-MSIQLKSGLLHYSYNG----ETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLR 1444
            AF+  +I + SG + YS+      +T+ +    +++G W  + ++     I +       
Sbjct: 4123 AFIEKTIAIASGKVTYSFRAGEASQTLTVTTLDVTNGNWQNVTLERDARTIRLATGTEFT 4182

Query: 1445 TVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPT-- 1502
                 +  +   G  I +  +GG       +  +   F+GC++D++I    + +N P   
Sbjct: 4183 QREFAVTPHNFLGANIRQWSLGGATQVPSGVTLEK--FKGCMEDLKINGVNTPMNGPNRF 4240

Query: 1503 ----VREN-VRDGCQSRADCMLSIC---PPYSKCVTSWDSSTCTCEAGRVGPQCVSACEL 1554
                 R   V +GC +   C  S C      + C   WDS TC   A          C+ 
Sbjct: 4241 LSAEARGGAVTEGCVTSGQCQSSPCANNKEKTACYEDWDSYTCVSAA---------PCQP 4291

Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGYT 1580
             PC   A C P Q  + + C C   YT
Sbjct: 4292 DPCKNNATCKP-QKDETFLCVCVGNYT 4317



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 5/72 (6%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C+S  D C+ + C   S C  +    TCTC+ G  G  C   ++ C+  PC       D 
Sbjct: 3733 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNCDVDINYCQSSPCMYNSTCKD- 3791

Query: 1567 TPKGYSCACEPG 1578
             P  + C C+ G
Sbjct: 3792 LPTSFECVCDFG 3803



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 30/149 (20%)

Query: 1536 TCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592
            TC+C+ G  G QC   V+ C   PC       D     + C+C PGY   T    ES  +
Sbjct: 3683 TCSCKPGFTGSQCEESVNDCNPNPCRNEGTCTDNN-GSFKCSCIPGY---TGRLCESDID 3738

Query: 1593 ECPGGWWGGSACGPC----ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            EC           PC    ACD T G +         C CK  +       +   CQ  +
Sbjct: 3739 EC--------LTNPCKHASACDNTPGGY--------TCTCKPGYTGQNCDVDINYCQS-S 3781

Query: 1649 AGSENSSCE--AATGQCHCRPGVIGRACD 1675
                NS+C+    + +C C  G  G  C+
Sbjct: 3782 PCMYNSTCKDLPTSFECVCDFGGRGERCE 3810



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C + PC + + C +    Y C CK G+TG++C
Sbjct: 3733 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNC 3771



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 40/130 (30%), Positives = 54/130 (41%), Gaps = 32/130 (24%)

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCK 1629
            +C+C+PG+T   S C ES  +  P          PC  + T      C   NG  KC C 
Sbjct: 3683 TCSCKPGFT--GSQCEESVNDCNPN---------PCRNEGT------CTDNNGSFKCSCI 3725

Query: 1630 ENHYK---PEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYAEV 1684
              +          ECL   C  A    S+C+   G   C C+PG  G+ CD   N Y + 
Sbjct: 3726 PGYTGRLCESDIDECLTNPCKHA----SACDNTPGGYTCTCKPGYTGQNCDVDIN-YCQS 3780

Query: 1685 TP---NSGCE 1691
            +P   NS C+
Sbjct: 3781 SPCMYNSTCK 3790



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 14/39 (35%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C+  PC N   C+D   ++ C C  G+TG+ C
Sbjct: 3695 CEESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLC 3733


>SB_34906| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 3922

 Score =  368 bits (905), Expect = e-101
 Identities = 408/1539 (26%), Positives = 647/1539 (42%), Gaps = 165/1539 (10%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND  P F++  Y+A VRE A  GTTV+T+KATD+D G    V Y ++  +        
Sbjct: 1786 DVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGS-------- 1837

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                         + F ID  SG L T+ S DRE  + ++V+V A D+ +     LS   
Sbjct: 1838 ------------DEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPG-ALSEEV 1884

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
             + V ++D+ND+ PQF +  +  SV E  S T    I ++ ATD D+G N+ + Y I GG
Sbjct: 1885 AVKVLVVDENDSPPQFDQAEFQTSVSE--SATIGTSILEVVATDQDIGDNAKLEYFISGG 1942

Query: 195  NTQMQFSIDSLS------GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            + +  F++ ++S      G+V +   LD+E   SY + + A DG     S TT++LI I 
Sbjct: 1943 DGRFWFAVQTISKSGRTYGEVQVDARLDFETKSSYTIDVTATDGRF---SATTRVLITIT 1999

Query: 249  DVNDNAPRFYT--------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            D ND  P F T         ++   VSE    G  +++V A D D   +  + YT+    
Sbjct: 2000 DANDIVPMFMTLTTPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD---SPNIQYTLEGSS 2056

Query: 301  YTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
                +          G + T  Q LDRE    +   V A DG     + +A         
Sbjct: 2057 SYFTIAARQEGGKFVGIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDI 2113

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRGRFSI 414
                  F    Y   + E++  GT V+ + A D D+     +  + Y +T  N  G+F I
Sbjct: 2114 NDNQPRFPNSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTLTD-NAGGKFKI 2172

Query: 415  TSQNGRGLITVAQPLDFKQE-RRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471
             +     L+T  + LD +     + +TV ATD G    S T +  I +TDAN++APVF  
Sbjct: 2173 DANTA--LVTTEEILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTK 2230

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              +  +V ED   G  V  VSATD+D G NA++ + ++    NE  A     F ++P  G
Sbjct: 2231 RIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTH--GNEPAA-----FYVDPSKG 2283

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTAN 589
             +    +L+      Y LTVT  D G+P LSD +   V I++ D NDN P+F    Y   
Sbjct: 2284 TVHVFDILNYTLRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKT 2343

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPAS-GVIRTNKAL 645
            + ED  VG+ V  V A D D G N +  +++   +P D  E     D +S G++RT   L
Sbjct: 2344 VAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGGNPDDLFEVVPNPDNSSLGIVRTRLPL 2403

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            DRE+   H L+  A D G    +    V + + D+ND+ P F+       I EN  +   
Sbjct: 2404 DRETTPIHHLEITAKDTGG--LTGKAHVWLTLLDVNDNGPWFQPPFFVGKIKENVNVKQF 2461

Query: 706  IGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSD-KAELVTMVDLDYESPRKKY 763
            + ++ A+DPD   N A   Y+I  G  S +F+ +    ++   ++ +    D E+    +
Sbjct: 2462 VTKVSANDPDTKNNGAPFTYAIYNGTVSGNFAFDIATITNVTTDMSSSGTFDRET-MTTW 2520

Query: 764  ELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
             + I       P   N   V + V D NDN P      II N+Y   F  GP  +    D
Sbjct: 2521 TIGIAGTDSGRPAKSNFTYVYVDVQDDNDNEPYDGRMTIIVNSYNGKFRGGPIAKTYYRD 2580

Query: 821  ADVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG----VNE 875
            AD   D   Y + S    N   ++ TTG ++ +  +      L      V  G     NE
Sbjct: 2581 ADYDGDVNTYTLQSQTGGNFFTVDTTTGEISAAKDIPVGEYSLVISVTEVNTGNPPRANE 2640

Query: 876  IK------AMMQLSVRLITEEMLLNSITVRLNDM-TAEQFLSPLLGFFIDGLAAIIPCPK 928
            +       +   + VR IT + + NS+ ++++DM   E F+       +  L+ +     
Sbjct: 2641 VNFPKTVTSRATVIVRDITSKAVSNSVALQISDMRKVEYFVGDYHDVVVGELSRMFGVSS 2700

Query: 929  ENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLAR 988
              I +FSVQ  + +    L+V F+ +    E         +  P  +   V  +R  L  
Sbjct: 2701 SGIEVFSVQ-PSPIKVMALDVQFAVKTGSDE---------YTKPYDVIRVVTDNRERLTN 2750

Query: 989  LATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPE 1048
            L  ++V     ++C  E      +C+ V++  +A    + D    +   P +S T    +
Sbjct: 2751 LG-LKVTSIGIDMCALER-ERVGKCINVVETSSAYKIASGD--YGKVPAPASSITLVSMD 2806

Query: 1049 GFTGVNCETILTKA-SCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRA 1107
                    TI+    +C  +     C +G  C      G   + C     Y    CE   
Sbjct: 2807 VVLRDKYVTIIEPGKNCSNENP---CLNGGTCHDTVPAG--WRVCQCPRGYRGPHCEQTT 2861

Query: 1108 RSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLALELVSS 1162
            R+F  +S++  P L       L  +F T+   GL+LY G       N   DFLA+ L   
Sbjct: 2862 RTFRGTSYIWLPKLTAYDIRELSFEFTTEFKDGLMLYQGPLKPGDNNGAKDFLAVFLDE- 2920

Query: 1163 EAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI--EYFNR-TITMILDDCDKVL 1219
                 G   +R S         +T   N+ D  WHTV+I  +  +R  I +I+D C    
Sbjct: 2921 -----GHLVVRVSLGYEPITINMTRRPNLNDKEWHTVQIIRDVIDRKMIRVIIDRCQSAQ 2975

Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279
             +        K      T +V              +L+  GPLQIGG+    +   +   
Sbjct: 2976 IVEENGRVFEKRDTCEITGRVKGRSV---------YLNGFGPLQIGGVETDLTFIGITTT 3026

Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339
             F GCI +     K  DL + +       GC    +  ++       E S +    +C C
Sbjct: 3027 GFRGCIRNIIDTEKMYDLRNPIKVVNAPEGCTLAGTCPNNCNDKGYCEPSLMAGKSMCVC 3086

Query: 1340 KEGHTGKDCADSTGPPW-------RFGGDGMLSFNPLLRPIQLPWLNA------LSIR-- 1384
              G+TG+ C D +   +       +F   G+ +   L++P  +P +N       L ++  
Sbjct: 3087 DFGYTGRACNDRSEANYYLENSFSQFLLTGIRARRELIQP-PVPLMNEYYTHINLQVKLD 3145

Query: 1385 --TRQRDAFVMS---------IQLKSGLLHYSYN-GETM---YLPMATLSDGAWHRIEIK 1429
              T+    F+ S         + +K  +L Y +  G+ M    +P   +SDG +H + + 
Sbjct: 3146 PGTKDCVLFLSSNSLGTEFNRLDVKDHMLRYIFRLGDRMKVLSIPQYNISDGKYHSVMVN 3205

Query: 1430 WLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGL 1468
              G    + +DY  +         K+     G I  GGL
Sbjct: 3206 REGNYAEMQIDYRAKMAGTTGGVQKLLNMGGGSIFTGGL 3244



 Score =  309 bits (759), Expect = 2e-83
 Identities = 253/837 (30%), Positives = 400/837 (47%), Gaps = 67/837 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V D N ++PVF    + AS  +   + T+V+ L   D+D+G   EV Y +       
Sbjct: 143 EVTVADTNTYTPVFSRTSFWASKPDTLPTDTSVMQLPIIDKDMGSLGEVTYQL------- 195

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           ++P  +            D FR+D  SG + +   L    +  Y +  KA D  SP    
Sbjct: 196 IDPTVSAGETSGY-----DRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPA--- 244

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI-KATDADVGANSAIR 188
           L +T  + +++   +D   +FS+  Y+ S+ E+     +P+  ++ +AT    G++S I 
Sbjct: 245 LEATVDVFISVYPSSDTPVRFSQNPYSASIAEN-----SPLNTEVFRATATKSGSSSGIA 299

Query: 189 YAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLL 244
           Y+++GG   N    FSIDS SG V L++ LD E+ +SY+L +R    GGS + +   + L
Sbjct: 300 YSLVGGQIENGNTMFSIDS-SGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATDVECL 358

Query: 245 INIRDVNDNAPRF-YTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           + + DVNDN P F +  + ++ V +N  P    I  ++A D+DEG NA++T ++     T
Sbjct: 359 VTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQG---T 415

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
              + PITID  S  + T+ +L   T   YQ+ V ATD G PP+ +  T           
Sbjct: 416 VPSNAPITIDTPSNVLKTTTKLS--TVIDYQITVRATDKGSPPQYSEITVIVKVLNIQTP 473

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
              F   +Y V++ E+   G  V+++ AT  D +  L Y    GN    F I S    G 
Sbjct: 474 PV-FGQAKYTVDVQENTKVGQQVISVKATYGDSNGLLQYSFVSGNLGDAFCIDSS---GQ 529

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           ITVAQPLD +    Y L V     G   D   V +++TD N+ +P F  + Y     ED 
Sbjct: 530 ITVAQPLDREVLPSYTLRVRVA-LGNNEDFTEVFVSLTDINDDSPTFTKSVYEFFANEDI 588

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT--TNKLLD 540
             GT++  V+ATD D G + QI+Y        +++     +F ++  TG I+  + K LD
Sbjct: 589 SSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSM----DKFDLDQTTGIISLASGKSLD 644

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E +S ++L V A D G   LS   +V I + D+NDN+P F    Y A +  DA V   V
Sbjct: 645 YEDISMHVLFVRAEDNGANKLSAIAEVRIYLRDINDNDPKFSAASYHAKLSLDAPVLEHV 704

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            QV ATD D   NGRI Y +     +EG+F +   +G+IR  K+L   + ++  L   A 
Sbjct: 705 VQVTATDLDTANNGRIRYSI-VAGNQEGAFQVLTDNGLIRVAKSLTTVAASSFLLTLEAA 763

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           D G P +  +V V + +  + D PP F  D +    +E       +   +A       + 
Sbjct: 764 DSGDPERKGSVNVQVNV-FLPDGPPKFVLDPVIVNATEGIAANQRVAVAKA-----ATSE 817

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
            + Y I  G+ ++ F++    G     ++T  +LDYE        +I   +      V+V
Sbjct: 818 ALKYEILSGNTNDMFAINPSSG----VILTTRELDYEEATGYIMNIIARDTRDRSASVQV 873

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG------RVPAYDADVTDKLQYRI 831
            I V ++NDN P+   F    N   D    GPF       R+ A D D+ D++ Y+I
Sbjct: 874 IINVVNINDNEPM---FPGETNGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKI 927



 Score =  270 bits (661), Expect = 1e-71
 Identities = 255/862 (29%), Positives = 387/862 (44%), Gaps = 94/862 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ P F  + Y  S++     GT+VLT+ ATD D G NA++ Y  +      
Sbjct: 1583 EVEVQDVNDNYPSFITRAYLGSIQNTKPIGTSVLTVSATDPDAGDNAKITYAFK------ 1636

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSD 128
             +P D               F ID  SG + T+ +L   K V     +V +  +A    D
Sbjct: 1637 -SPNDK--------------FEIDSTSGDIRTKVALTGTKDVNEKMTVVASNTEAIQGGD 1681

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              +      V I   +   P   +  +T  + E +SV  N  + K+ A         +I 
Sbjct: 1682 ANNRDRETEVTIYITDLAPPVCDKNLFTARILESLSV--NSDVLKVSA---QAPGGKSIV 1736

Query: 189  YAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLI 245
            Y+ +  N  +  +FS+++ +G +     LDYEQ+             SP  ++   Q   
Sbjct: 1737 YSPVKANADIDEKFSVET-NGQIKTASQLDYEQL-------------SPGDKTFKLQCCD 1782

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + DVND+ P F    +   V EN PIG +++ ++A D D G    +TY +         
Sbjct: 1783 TLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFL-----KAGS 1837

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXX 363
            D    ID  SG + T    DRE Q+ + ++V A D G+ P   S                
Sbjct: 1838 DEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSP 1897

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI--TSQNG 419
              F   +++  ++E    GT ++ + ATD D  ++ +L Y I+GG+ R  F++   S++G
Sbjct: 1898 PQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQTISKSG 1957

Query: 420  R--GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN------ 471
            R  G + V   LDF+ +  Y + V+ATD G  S T  V I ITDAN+  P+F        
Sbjct: 1958 RTYGEVQVDARLDFETKSSYTIDVTATD-GRFSATTRVLITITDANDIVPMFMTLTTPTL 2016

Query: 472  -AP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
             +P YT  V E    G  VL V A D+D   N Q T   SS     A      +FV    
Sbjct: 2017 LSPIYTGRVSEMTGSGVEVLKVYAVDTD-SPNIQYTLEGSSSYFTIAARQEGGKFV---- 2071

Query: 530  TGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
             G I+T ++ LDRE    +   V A+DG     + +  +EI+V D+NDN+P F   LY  
Sbjct: 2072 -GIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFPNSLYVG 2127

Query: 589  NIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
             + E+   GTSV  V A D D   +G N  I Y L   D   G F ID  + ++ T + L
Sbjct: 2128 YVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTL--TDNAGGKFKIDANTALVTTEEIL 2185

Query: 646  DRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            DRE S  +  +  +A D G    S+T +  I + D ND  PVF        +SE+   G 
Sbjct: 2186 DRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGY 2245

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
             +  + A D D GPNA + + +  G++  +F ++  +G+     V + D+   + RK Y 
Sbjct: 2246 VVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGT-----VHVFDILNYTLRKSYN 2300

Query: 765  LVIRAA--SPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
            L +  +    P+ +D     V I +TD NDNAP+    Q      +D     P   V A 
Sbjct: 2301 LTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAV 2360

Query: 820  DADVTD--KLQYRILSGNNANL 839
            D D  D  K  + I  GN  +L
Sbjct: 2361 DYDSGDNAKFVFDITGGNPDDL 2382



 Score =  252 bits (616), Expect = 4e-66
 Identities = 253/899 (28%), Positives = 401/899 (44%), Gaps = 102/899 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++NV   N + P F  +  +A+++E    G  + T+ ATD+D G+N EVEY I  V    
Sbjct: 1474 RVNVEYKNMYRPEFT-KCGKATIQENLLKGQLIATVTATDRDQGRNGEVEYKIVPVGG-- 1530

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVS 127
                             QD F I+ ++G ++T +SLDRE  A YTV++ A D       +
Sbjct: 1531 -----------------QDFFTINNKTGEVITTSSLDRETKATYTVIITAEDGGHGKDPA 1573

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            +RL S   + V + D NDNYP F  + Y  S+     +  +  +  + ATD D G N+ I
Sbjct: 1574 ERLMSYCFLEVEVQDVNDNYPSFITRAYLGSIQNTKPIGTS--VLTVSATDPDAGDNAKI 1631

Query: 188  RYAIIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRA-----QDGGSPSRSNTT 241
             YA    N   +F IDS SGD+ + V     + V     V+ +     Q G + +R   T
Sbjct: 1632 TYAFKSPND--KFEIDSTSGDIRTKVALTGTKDVNEKMTVVASNTEAIQGGDANNRDRET 1689

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            ++ I I D+    P    +LF   + E++ +   +++V A  A  G    + Y+      
Sbjct: 1690 EVTIYITDL--APPVCDKNLFTARILESLSVNSDVLKVSA-QAPGG--KSIVYS----PV 1740

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
              N D    ID +   V T+GQ+   +Q  Y+ L      GD  ++              
Sbjct: 1741 KANAD----IDEKFS-VETNGQIKTASQLDYEQL----SPGD--KTFKLQCCDTLEDVND 1789

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419
                F  G Y+  + E+ P GT V+T+ ATD D  +   + Y +  G+    F+I   + 
Sbjct: 1790 DKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSDE-HFAIDVNS- 1847

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYT 475
             G +T  +  D + +  + + V A D G      S+   V++ + D N+  P F+ A + 
Sbjct: 1848 -GTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQ 1906

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT-GAIT 534
             SV E A IGT++L V ATD D+G NA++ Y +S        A   Q    + +T G + 
Sbjct: 1907 TSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFA--VQTISKSGRTYGEVQ 1964

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK--------QQLY 586
             +  LD ET S Y + VTA DG     S TT V I++ D ND  P+F           +Y
Sbjct: 1965 VDARLDFETKSSYTIDVTATDG---RFSATTRVLITITDANDIVPMFMTLTTPTLLSPIY 2021

Query: 587  TANIMEDALVGTSVSQVGATDAD-----VGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
            T  + E    G  V +V A D D       L G   Y      +E G FV     G+I T
Sbjct: 2022 TGRVSEMTGSGVEVLKVYAVDTDSPNIQYTLEGSSSYFTIAARQEGGKFV-----GIIST 2076

Query: 642  -NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
             ++ LDRE+        +A DG     + +  + I + DIND+ P F +     Y+ EN 
Sbjct: 2077 GSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENK 2133

Query: 701  PIGTTIGEIRAHDPDE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
              GT++  ++AHD D+   G NA + Y++   +    F ++    ++ A + T   LD E
Sbjct: 2134 AAGTSVMYVQAHDDDDPYLGGNAEIRYTLT-DNAGGKFKID----ANTALVTTEEILDRE 2188

Query: 758  SPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814
            +    + + + A    +  L       I VTD ND+APV           +D  P     
Sbjct: 2189 TSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVT 2248

Query: 815  RVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             V A D D     +L++ +  GN      ++ + G++ +   LN  + K   + V+V+D
Sbjct: 2249 SVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVFDILNYTLRKSYNLTVTVSD 2307



 Score =  223 bits (546), Expect = 1e-57
 Identities = 210/803 (26%), Positives = 333/803 (41%), Gaps = 45/803 (5%)

Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           S D E   +Y + + A    +P  + ++S++ + + I D+ D  PQFS+  Y VSV ED 
Sbjct: 3   SFDYETADKYRIQISAQSGTAP--NIMTSSSDVAITIKDEKDP-PQFSQSEYKVSVPEDA 59

Query: 164 SVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQF-SIDSLSGDVSLV--KTLDYEQ 219
           SV    +   I+  D D +          +     + + S+    G+   V  KTLD   
Sbjct: 60  SVRST-LSRGIRFVDEDTLSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLDTFV 118

Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
              +   ++  D   P    TT++ + + D N   P F  + F  S  + +P   S++++
Sbjct: 119 ASKFTFDMKVTDKNFPGMFATTKVEVTVADTNTYTPVFSRTSFWASKPDTLPTDTSVMQL 178

Query: 280 QAYDADEGVNAELTYTMTDKDY----TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
              D D G   E+TY + D       T   D    +D  SG + ++  L   T   Y+L 
Sbjct: 179 PIIDKDMGSLGEVTYQLIDPTVSAGETSGYD-RFRVDD-SGMIESTNILTANT--LYKLQ 234

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
             A DGG P   AT                F    Y   +AE+ P  T V   TAT +  
Sbjct: 235 AKAKDGGSPALEATVDVFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATATKSGS 294

Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM- 454
            + + Y + GG      ++ S +  G + + + LD ++ + Y L V  T +GG    A  
Sbjct: 295 SSGIAYSLVGGQIENGNTMFSIDSSGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATD 354

Query: 455 --VQINITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDSDVGINAQITYSLSS 510
               + +TD N+  P+F           D  AP  T +  + A DSD G NAQ+T S+  
Sbjct: 355 VECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQG 414

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
            + + A    D      P     TT KL    T+  Y +TV A D G P       V + 
Sbjct: 415 TVPSNAPITID-----TPSNVLKTTTKL---STVIDYQITVRATDKGSPPQYSEITVIVK 466

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           V+++    PVF Q  YT ++ E+  VG  V  V AT  D   NG + Y     +  + +F
Sbjct: 467 VLNI-QTPPVFGQAKYTVDVQENTKVGQQVISVKATYGD--SNGLLQYSFVSGNLGD-AF 522

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            ID +SG I   + LDRE + ++ L+     G     +    V + + DIND  P F   
Sbjct: 523 CID-SSGQITVAQPLDREVLPSYTLRVRVALGNNEDFTE---VFVSLTDINDDSPTFTKS 578

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF-SLETRQGSDKAELV 749
              F+ +E+   GT+IG++ A D D G +  + Y      D  S    +  Q +    L 
Sbjct: 579 VYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGIISLA 638

Query: 750 TMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
           +   LDYE     + L +RA    +  L     V I + D+NDN P             D
Sbjct: 639 SGKSLDYED-ISMHVLFVRAEDNGANKLSAIAEVRIYLRDINDNDPKFSAASYHAKLSLD 697

Query: 807 CFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864
              +    +V A D D  +  +++Y I++GN      +    G + ++  L T       
Sbjct: 698 APVLEHVVQVTATDLDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVAKSLTTVAASSFL 757

Query: 865 MEVSVTD-GVNEIKAMMQLSVRL 886
           + +   D G  E K  + + V +
Sbjct: 758 LTLEAADSGDPERKGSVNVQVNV 780



 Score =  221 bits (541), Expect = 5e-57
 Identities = 237/898 (26%), Positives = 389/898 (43%), Gaps = 75/898 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69
           I + D  D  P F   +Y+ SV E AS  +T+   ++  D+D   + ++E ++E +T+  
Sbjct: 35  ITIKDEKD-PPQFSQSEYKVSVPEDASVRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRI 92

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             P D           VQD     G     +   +LD    +++T  +K TD+  P    
Sbjct: 93  --PLD-------YLSVVQD-----GGECKFVIEKTLDTFVASKFTFDMKVTDKNFP---G 135

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           + +T  + V + D N   P FS  ++  S  + +  TD  V+ ++   D D+G+   + Y
Sbjct: 136 MFATTKVEVTVADTNTYTPVFSRTSFWASKPDTLP-TDTSVM-QLPIIDKDMGSLGEVTY 193

Query: 190 AII-----GGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            +I      G T    +F +D  SG +     L    +  Y+L  +A+DGGSP+   T  
Sbjct: 194 QLIDPTVSAGETSGYDRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPALEATVD 250

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           + I++   +D   RF  + +  S++EN P+   + R  A     G ++ + Y++      
Sbjct: 251 VFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATA--TKSGSSSGIAYSLVGGQIE 308

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT-DGGDPPRSATATXXXXXXXXXX 361
            N +   +ID  SG V    QLDRE    Y+L V  T  GG    +              
Sbjct: 309 -NGNTMFSIDS-SGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATDVECLVTVTDVND 366

Query: 362 XXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQN 418
               F   +   +   D   P  T + TL A D+DE       ++  G       IT   
Sbjct: 367 NTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQGTVPSNAPITIDT 426

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTAS 477
              ++     L    +  Y +TV ATD G     + + + +   N    PVF  A YT  
Sbjct: 427 PSNVLKTTTKLSTVID--YQITVRATDKGSPPQYSEITVIVKVLNIQTPPVFGQAKYTVD 484

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V E+  +G  V+ V AT  D   N  + YS  S    +A       F I+  +G IT  +
Sbjct: 485 VQENTKVGQQVISVKATYGDS--NGLLQYSFVSGNLGDA-------FCID-SSGQITVAQ 534

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LDRE +  Y L V    G   +  D T+V +S+ D+ND+ P F + +Y     ED   G
Sbjct: 535 PLDREVLPSYTLRVRVALG---NNEDFTEVFVSLTDINDDSPTFTKSVYEFFANEDISSG 591

Query: 598 TSVSQVGATDADVGLNGRIHYE-LDPKDREE-GSFVIDPASGVIR--TNKALDRESVATH 653
           TS+ +V ATD D G +G+I Y  L   D +    F +D  +G+I   + K+LD E ++ H
Sbjct: 592 TSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGIISLASGKSLDYEDISMH 651

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            L   A D G    S+   V I + DIND+ P F +      +S ++P+   + ++ A D
Sbjct: 652 VLFVRAEDNGANKLSAIAEVRIYLRDINDNDPKFSAASYHAKLSLDAPVLEHVVQVTATD 711

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKKYELVIRAAS- 771
            D   N  + YSI  G+   +F + T  G  + A+ +T V          + L + AA  
Sbjct: 712 LDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVAKSLTTV------AASSFLLTLEAADS 765

Query: 772 --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829
             P     V V++ V  + D  P      +I N  +    +    RV    A  ++ L+Y
Sbjct: 766 GDPERKGSVNVQVNVF-LPDGPPKFVLDPVIVNATEG---IAANQRVAVAKAATSEALKY 821

Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            ILSGN  ++  +N ++G +  + +L+        M +   D   +  A +Q+ + ++
Sbjct: 822 EILSGNTNDMFAINPSSGVILTTRELDYEEATGYIMNIIARD-TRDRSASVQVIINVV 878



 Score =  195 bits (476), Expect = 4e-49
 Identities = 208/844 (24%), Positives = 350/844 (41%), Gaps = 85/844 (10%)

Query: 21   PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80
            PVF   +Y   V+E    G  V+++KAT  D   N  ++Y+                   
Sbjct: 474  PVFGQAKYTVDVQENTKVGQQVISVKATYGD--SNGLLQYSF------------------ 513

Query: 81   XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140
                 + D F ID  SG +     LDRE +  YT+ V+       + +    T  + V++
Sbjct: 514  -VSGNLGDAFCIDS-SGQITVAQPLDREVLPSYTLRVRVA-----LGNNEDFTE-VFVSL 565

Query: 141  IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQ 197
             D ND+ P F++  Y    +EDIS      I K+ ATD D G++  I Y  +  +   + 
Sbjct: 566  TDINDDSPTFTKSVYEFFANEDIS--SGTSIGKVAATDRDSGSHGQISYRFLYASDIQSM 623

Query: 198  MQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
             +F +D  +G +SL   K+LDYE +  + L +RA+D G+   S   ++ I +RD+NDN P
Sbjct: 624  DKFDLDQTTGIISLASGKSLDYEDISMHVLFVRAEDNGANKLSAIAEVRIYLRDINDNDP 683

Query: 256  RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
            +F  + +   +S + P+   +V+V A D D   N  + Y++      GN +    +   +
Sbjct: 684  KFSAASYHAKLSLDAPVLEHVVQVTATDLDTANNGRIRYSIV----AGNQEGAFQVLTDN 739

Query: 316  GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            G +  +  L     + + L + A D GDP R  +                F+     V  
Sbjct: 740  GLIRVAKSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNVFLPDGPPK-FVLDPVIVNA 798

Query: 376  AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
             E       V    A  ++    L YEI  GNT   F+I   +G  +I   + LD+++  
Sbjct: 799  TEGIAANQRVAVAKAATSEA---LKYEILSGNTNDMFAINPSSG--VILTTRELDYEEAT 853

Query: 436  RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE---NAPYTASVFEDAPIGTTVLVVS 492
             Y++ + A D+  RS +  V IN+ + N+  P+F    N      V      G     ++
Sbjct: 854  GYIMNIIARDTRDRSASVQVIINVVNINDNEPMFPGETNGQIDRKVAGPFAPGVIATRLT 913

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            A D D+G   ++ Y +S E  N         F I+ +   I  N L  +   S +  T+ 
Sbjct: 914  AVDKDIG--DRVYYKISIEAEN--------YFTIDERGQLICKNDL--KGIASPFRFTIE 961

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            ARDGG+P    T +V +  V+        KQQ     + E    GT +++V       G 
Sbjct: 962  ARDGGLPQKVHTANVLLVFVNYRP-----KQQPVRVIVPETTRAGTVITRV-PRYFPTG- 1014

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
                  E      E+ +F ID   G +  N+ LD E +A   L  V     + P  + + 
Sbjct: 1015 ------EFSIVYPEKTNFTID-NDGNVTLNRPLDYEEIA-FTLITVREKQASGPLENYID 1066

Query: 673  VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            V I + D ND+ P F        ++ NS  G T  +++A D D G N ++ + ++     
Sbjct: 1067 VEITVLDENDNAPFFTMISTLGRVNSNSRAGATAFQLQARDLDSGSNGLIGFQLENIPTL 1126

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
               +  TRQ       + +     ++ R   +++      P  N  +  + +  V  + P
Sbjct: 1127 FMINPLTRQ-------IEVGQPRLQTSRYGLDIIPFDYGKPSVNGTKATVDIETV-QSPP 1178

Query: 793  VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852
            V  +    F   +    +   G V A       +L Y I+ GN  +  L  +  G + L+
Sbjct: 1179 VFNESSYTFTVSERAPTMTKIGDVTAVSVSGA-RLSYTIIEGNTGDKFLAKD-NGDIVLN 1236

Query: 853  PQLN 856
              L+
Sbjct: 1237 SLLD 1240



 Score =  195 bits (475), Expect = 5e-49
 Identities = 214/850 (25%), Positives = 366/850 (43%), Gaps = 92/850 (10%)

Query: 96   SGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
            +G ++  + LD E+  + + + V+A +Q   +   LSS   + + +I+ ND +P F +  
Sbjct: 1230 NGDIVLNSLLDFERDQSVFNLKVEAKEQ---IPKGLSSEVDVTITVINANDFHPYFDDPV 1286

Query: 155  YTVSVDEDISVTDNPVIAKIKATDADVGAN-----SAIRYAIIGGNTQMQFSIDSLSGDV 209
            Y + V E   V D  VI  + A D D  ++       ++Y++  G +   F ID  +G +
Sbjct: 1287 YRLKVPESRGVGD--VIMTVTARDCDCPSDCTCPVGQLKYSVEAGTS---FDIDQ-TGAI 1340

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
             + +TLDYE  +   L + A D G    +  T +++ + D NDNAP F  + +   ++ +
Sbjct: 1341 VVARTLDYETSKVQVLKVMASDQGEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTAD 1400

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
               G  I  V A D D+    ++ Y++              ++  +G +  +  L    +
Sbjct: 1401 ASTGSMIGAVIARDQDQDDIEKVRYSVVS-------GTEFNVNTETGVLTVAKDLSTGAK 1453

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
            ++Y + + ATD     +S  A               F     +  + E+   G  + T+T
Sbjct: 1454 SEYSMEIRATDS---TKSNDARVRVNVEYKNMYRPEFTKCG-KATIQENLLKGQLIATVT 1509

Query: 390  ATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            ATD D+  +  + Y+I     +  F+I ++ G  + T    LD + +  Y + ++A D G
Sbjct: 1510 ATDRDQGRNGEVEYKIVPVGGQDFFTINNKTGEVITT--SSLDRETKATYTVIITAEDGG 1567

Query: 448  GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
               D A        +++ + D N+  P F    Y  S+    PIGT+VL VSATD D G 
Sbjct: 1568 HGKDPAERLMSYCFLEVEVQDVNDNYPSFITRAYLGSIQNTKPIGTSVLTVSATDPDAGD 1627

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLTVTARD 555
            NA+ITY+  S          + +F I+  +G I T   L       E M+       A  
Sbjct: 1628 NAKITYAFKSP---------NDKFEIDSTSGDIRTKVALTGTKDVNEKMTVVASNTEAIQ 1678

Query: 556  GGVPSLSD-TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
            GG  +  D  T+V I + D+    PV  + L+TA I+E   V + V +V A     G   
Sbjct: 1679 GGDANNRDRETEVTIYITDL--APPVCDKNLFTARILESLSVNSDVLKVSAQAP--GGKS 1734

Query: 615  RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
             ++  +      +  F ++  +G I+T   LD E ++  D            ++  +   
Sbjct: 1735 IVYSPVKANADIDEKFSVE-TNGQIKTASQLDYEQLSPGD------------KTFKLQCC 1781

Query: 675  IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
              +ED+ND  P F+       + EN+PIGTT+  I+A D D G   VV Y +K G D + 
Sbjct: 1782 DTLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSDEH- 1840

Query: 735  FSLETRQGSDKAELVTMVDLDYESPRKKYELVI---RAASP-PLWNDVRVEILVTDVNDN 790
            F+++   G+    L T    D E       +VI   +  +P  L  +V V++LV D ND+
Sbjct: 1841 FAIDVNSGT----LTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDS 1896

Query: 791  APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN------ANLILL 842
             P     +   +  +          V A D D+ D  KL+Y I  G+         +   
Sbjct: 1897 PPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQTISKS 1956

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLND 902
              T G + +  +L+       T++V+ TDG          + R++      N I      
Sbjct: 1957 GRTYGEVQVDARLDFETKSSYTIDVTATDG------RFSATTRVLITITDANDIVPMFMT 2010

Query: 903  MTAEQFLSPL 912
            +T    LSP+
Sbjct: 2011 LTTPTLLSPI 2020



 Score =  184 bits (448), Expect = 9e-46
 Identities = 183/674 (27%), Positives = 303/674 (44%), Gaps = 59/674 (8%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID      L R  LD E++A   + V+    + P+ + +     + + ++D+NDN P 
Sbjct: 1026 FTIDNDGNVTLNRP-LDYEEIAFTLITVREKQASGPLENYID----VEITVLDENDNAPF 1080

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            F+  +    V+ +          +++A D D G+N  I + +   N    F I+ L+  +
Sbjct: 1081 FTMISTLGRVNSNSRA--GATAFQLQARDLDSGSNGLIGFQL--ENIPTLFMINPLTRQI 1136

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
             + +     Q   Y L I   D G PS  N T+  ++I  V  + P F  S +  +VSE 
Sbjct: 1137 EVGQ--PRLQTSRYGLDIIPFDYGKPS-VNGTKATVDIETV-QSPPVFNESSYTFTVSER 1192

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-T 328
             P    I  V A        A L+YT+ + + TG+  L       +G +  +  LD E  
Sbjct: 1193 APTMTKIGDVTAVSVS---GARLSYTIIEGN-TGDKFLA----KDNGDIVLNSLLDFERD 1244

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            Q+ + L V A +      S+                 F    Y +++ E    G  ++T+
Sbjct: 1245 QSVFNLKVEAKEQIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIMTV 1304

Query: 389  TATDAD--ED-----NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            TA D D   D      +L Y +  G +   F I   +  G I VA+ LD++  +  VL V
Sbjct: 1305 TARDCDCPSDCTCPVGQLKYSVEAGTS---FDI---DQTGAIVVARTLDYETSKVQVLKV 1358

Query: 442  SATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
             A+D G +  TA+  V + + D N+ APVF+   Y   +  DA  G+ +  V A D D  
Sbjct: 1359 MASDQGEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQD 1418

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
               ++ YS+ S            +F +N +TG +T  K L     S Y + + A D    
Sbjct: 1419 DIEKVRYSVVS----------GTEFNVNTETGVLTVAKDLSTGAKSEYSMEIRATDS--- 1465

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            + S+   V ++V   N   P F  +   A I E+ L G  ++ V ATD D G NG + Y+
Sbjct: 1466 TKSNDARVRVNVEYKNMYRPEF-TKCGKATIQENLLKGQLIATVTATDRDQGRNGEVEYK 1524

Query: 620  LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG---TPPQ--SSTVIVH 674
            + P   ++  F I+  +G + T  +LDRE+ AT+ +   A DGG    P +   S   + 
Sbjct: 1525 IVPVGGQD-FFTINNKTGEVITTSSLDRETKATYTVIITAEDGGHGKDPAERLMSYCFLE 1583

Query: 675  IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
            ++++D+ND+ P F +      I    PIGT++  + A DPD G NA + Y+ K  +D   
Sbjct: 1584 VEVQDVNDNYPSFITRAYLGSIQNTKPIGTSVLTVSATDPDAGDNAKITYAFKSPND--K 1641

Query: 735  FSLETRQGSDKAEL 748
            F +++  G  + ++
Sbjct: 1642 FEIDSTSGDIRTKV 1655



 Score =  178 bits (434), Expect = 5e-44
 Identities = 225/892 (25%), Positives = 366/892 (41%), Gaps = 103/892 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND+ P F    Y A +   A     V+ + ATD D   N  + Y+I  V    
Sbjct: 672  RIYLRDINDNDPKFSAASYHAKLSLDAPVLEHVVQVTATDLDTANNGRIRYSI--VAG-- 727

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N E A              F++   +G +    SL     + + + ++A D   P  +R
Sbjct: 728  -NQEGA--------------FQVLTDNGLIRVAKSLTTVAASSFLLTLEAADSGDP--ER 770

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              S   + VN+    D  P+F      V+  E I+      +AK   ++A       ++Y
Sbjct: 771  KGSV-NVQVNVFLP-DGPPKFVLDPVIVNATEGIAANQRVAVAKAATSEA-------LKY 821

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ GNT   F+I+  SG +   + LDYE+   Y + I A+D  +  RS + Q++IN+ +
Sbjct: 822  EILSGNTNDMFAINPSSGVILTTRELDYEEATGYIMNIIARD--TRDRSASVQVIINVVN 879

Query: 250  VNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            +NDN P F           V+     G    R+ A D D G       ++  ++Y     
Sbjct: 880  INDNEPMFPGETNGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISIEAENY----- 934

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               TID R G +     L +   + ++  + A DGG P +  TA               +
Sbjct: 935  --FTIDER-GQLICKNDL-KGIASPFRFTIEARDGGLPQKVHTANVLLVFVN-------Y 983

Query: 367  MPGQYEVELAEDEPP--GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
             P Q  V +   E    GT +  +       +  + Y       +  F+I +    G +T
Sbjct: 984  RPKQQPVRVIVPETTRAGTVITRVPRYFPTGEFSIVYP-----EKTNFTIDND---GNVT 1035

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAP 483
            + +PLD+++    ++TV    + G  +  + V+I + D N+ AP F        V  ++ 
Sbjct: 1036 LNRPLDYEEIAFTLITVREKQASGPLENYIDVEITVLDENDNAPFFTMISTLGRVNSNSR 1095

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             G T   + A D D G N  I + L +  +          F+INP T  I   +   R  
Sbjct: 1096 AGATAFQLQARDLDSGSNGLIGFQLENIPT---------LFMINPLTRQIEVGQ--PRLQ 1144

Query: 544  MSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             S Y L +   D G PS++ T   V+I  V    + PVF +  YT  + E A   T +  
Sbjct: 1145 TSRYGLDIIPFDYGKPSVNGTKATVDIETVQ---SPPVFNESSYTFTVSERAPTMTKIGD 1201

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVAID 661
            V A         R+ Y +   +   G   +   +G I  N  LD E   +  +LK  A +
Sbjct: 1202 VTAVSVS---GARLSYTII--EGNTGDKFLAKDNGDIVLNSLLDFERDQSVFNLKVEAKE 1256

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-----E 716
                  SS V V I + + ND  P F+       + E+  +G  I  + A D D      
Sbjct: 1257 QIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIMTVTARDCDCPSDCT 1316

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-ASPPLW 775
             P   + YS++ G    SF ++         +V    LDYE+ + +   V+ +     ++
Sbjct: 1317 CPVGQLKYSVEAG---TSFDID-----QTGAIVVARTLDYETSKVQVLKVMASDQGEKVF 1368

Query: 776  NDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRIL 832
              V  V + + D NDNAPV K    +F    D       G V A D D  D  K++Y ++
Sbjct: 1369 TAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQDDIEKVRYSVV 1428

Query: 833  SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            SG   N+   N  TG +T++  L+T      +ME+  TD      A ++++V
Sbjct: 1429 SGTEFNV---NTETGVLTVAKDLSTGAKSEYSMEIRATDSTKSNDARVRVNV 1477



 Score =  167 bits (405), Expect = 1e-40
 Identities = 177/651 (27%), Positives = 279/651 (42%), Gaps = 50/651 (7%)

Query: 200  FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
            F+ID+  G+V+L + LDYE++    + +R +    P   N   + I + D NDNAP F  
Sbjct: 1026 FTIDN-DGNVTLNRPLDYEEIAFTLITVREKQASGPLE-NYIDVEITVLDENDNAPFFTM 1083

Query: 260  SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
                  V+ N   G +  ++QA D D G N  + + +       N+     I+P +  + 
Sbjct: 1084 ISTLGRVNSNSRAGATAFQLQARDLDSGSNGLIGFQLE------NIPTLFMINPLTRQIE 1137

Query: 320  TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
              GQ   +T ++Y L +   D G P  S   T              F    Y   ++E  
Sbjct: 1138 V-GQPRLQT-SRYGLDIIPFDYGKP--SVNGTKATVDIETVQSPPVFNESSYTFTVSERA 1193

Query: 380  PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR-YV 438
            P  T +  +TA       RL Y I  GNT  +F +   NG   I +   LDF++++  + 
Sbjct: 1194 PTMTKIGDVTAVSVS-GARLSYTIIEGNTGDKF-LAKDNGD--IVLNSLLDFERDQSVFN 1249

Query: 439  LTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            L V A +    G S    V I + +AN++ P F++  Y   V E   +G  ++ V+A D 
Sbjct: 1250 LKVEAKEQIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIMTVTARDC 1309

Query: 497  DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
            D   +         + S EA    D       QTGAI   + LD ET    +L V A D 
Sbjct: 1310 DCPSDCTCPVG-QLKYSVEAGTSFDID-----QTGAIVVARTLDYETSKVQVLKVMASDQ 1363

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            G    +  T V +++ D NDN PVFK+  Y   +  DA  G+ +  V A D D     ++
Sbjct: 1364 GEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQDDIEKV 1423

Query: 617  HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
             Y +         F ++  +GV+   K L   + + + ++  A D     +S+   V + 
Sbjct: 1424 RYSV----VSGTEFNVNTETGVLTVAKDLSTGAKSEYSMEIRATDS---TKSNDARVRVN 1476

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
            +E  N   P F + C    I EN   G  I  + A D D+G N  V Y I      + F+
Sbjct: 1477 VEYKNMYRPEF-TKCGKATIQENLLKGQLIATVTATDRDQGRNGEVEYKIVPVGGQDFFT 1535

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVIRA--------ASPPLWNDVRVEILVTDVN 788
            +  + G    E++T   LD E+ +  Y ++I A         +  L +   +E+ V DVN
Sbjct: 1536 INNKTG----EVITTSSLDRET-KATYTVIITAEDGGHGKDPAERLMSYCFLEVEVQDVN 1590

Query: 789  DNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSGNN 836
            DN P     +    + ++  P+G     V A D D  D  K+ Y   S N+
Sbjct: 1591 DNYPSFIT-RAYLGSIQNTKPIGTSVLTVSATDPDAGDNAKITYAFKSPND 1640



 Score =  163 bits (395), Expect = 2e-39
 Identities = 175/700 (25%), Positives = 310/700 (44%), Gaps = 50/700 (7%)

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
           +++ DYE    YR+ I AQ G +P+  ++++ + I I+D  D  P+F  S ++ SV E+ 
Sbjct: 1   MRSFDYETADKYRIQISAQSGTAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEDA 59

Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQLDRETQ 329
            +  ++ R   +  ++ ++ +L  +M +      +D L +  D           LD    
Sbjct: 60  SVRSTLSRGIRFVDEDTLSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLDTFVA 119

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
           +K+   +  TD   P   AT                F    +     +  P  T V+ L 
Sbjct: 120 SKFTFDMKVTDKNFPGMFATTKVEVTVADTNTYTPVFSRTSFWASKPDTLPTDTSVMQLP 179

Query: 390 ATDADEDN--RLHYE-----ITGGNTRG--RFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             D D  +   + Y+     ++ G T G  RF +   +  G+I     L       Y L 
Sbjct: 180 IIDKDMGSLGEVTYQLIDPTVSAGETSGYDRFRV---DDSGMIESTNIL--TANTLYKLQ 234

Query: 441 VSATDSGGRSDTAMVQINIT-DANNYAPV-FENAPYTASVFEDAPIGTTVLVVSATDSDV 498
             A D G  +  A V + I+   ++  PV F   PY+AS+ E++P+ T V   +AT S  
Sbjct: 235 AKAKDGGSPALEATVDVFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATATKS-- 292

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           G ++ I YSL   +  + + + +  F I+  +G +   + LDRE    Y L V     G 
Sbjct: 293 GSSSGIAYSL---VGGQ-IENGNTMFSID-SSGRVLLLRQLDRERTKSYKLYVRGTYTG- 346

Query: 559 PSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQVGATDADVGLNG 614
            SL+  TDVE  ++V DVNDN P+F         + D  A   T ++ + A D+D G N 
Sbjct: 347 GSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANA 406

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
           ++   +           ID  S V++T   L   +V  + +   A D G+PPQ S + V 
Sbjct: 407 QVTMSIQGTVPSNAPITIDTPSNVLKTTTKL--STVIDYQITVRATDKGSPPQYSEITVI 464

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           +K+ +I  +PPVF     T  + EN+ +G  +  ++A   D   N ++ YS   G+  ++
Sbjct: 465 VKVLNI-QTPPVFGQAKYTVDVQENTKVGQQVISVKATYGDS--NGLLQYSFVSGNLGDA 521

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794
           F +++       ++     LD E     Y L +R A     +   V + +TD+ND++P  
Sbjct: 522 FCIDS-----SGQITVAQPLDRE-VLPSYTLRVRVALGNNEDFTEVFVSLTDINDDSPTF 575

Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGN---NANLILLNETTGSM 849
                 F   +D       G+V A D D     ++ YR L  +   + +   L++TTG +
Sbjct: 576 TKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGII 635

Query: 850 TLSPQLNTNVPKLATMEVSV---TDGVNEIKAMMQLSVRL 886
           +L+   + +   ++   + V    +G N++ A+ ++ + L
Sbjct: 636 SLASGKSLDYEDISMHVLFVRAEDNGANKLSAIAEVRIYL 675



 Score =  112 bits (269), Expect = 4e-24
 Identities = 120/458 (26%), Positives = 188/458 (41%), Gaps = 35/458 (7%)

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            I V QP    Q  RY L +   D G  S          +     PVF  + YT +V E A
Sbjct: 1136 IEVGQPR--LQTSRYGLDIIPFDYGKPSVNGTKATVDIETVQSPPVFNESSYTFTVSERA 1193

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P  T +  V+A        A+++Y++    + +     D         G I  N LLD E
Sbjct: 1194 PTMTKIGDVTAVSVS---GARLSYTIIEGNTGDKFLAKDN--------GDIVLNSLLDFE 1242

Query: 543  T-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
               S + L V A++     LS   DV I+V++ ND  P F   +Y   + E   VG  + 
Sbjct: 1243 RDQSVFNLKVEAKEQIPKGLSSEVDVTITVINANDFHPYFDDPVYRLKVPESRGVGDVIM 1302

Query: 602  QVGATDADVGLN-----GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
             V A D D   +     G++ Y ++       SF ID  +G I   + LD E+     LK
Sbjct: 1303 TVTARDCDCPSDCTCPVGQLKYSVEAGT----SFDIDQ-TGAIVVARTLDYETSKVQVLK 1357

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             +A D G    ++   V + +ED ND+ PVF+ +   F ++ ++  G+ IG + A D D+
Sbjct: 1358 VMASDQGEKVFTAVTFVVVTLEDTNDNAPVFKRNDYLFRMTADASTGSMIGAVIARDQDQ 1417

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
                 V YS+  G +   F++ T  G     L    DL     + +Y + IRA      N
Sbjct: 1418 DDIEKVRYSVVSGTE---FNVNTETGV----LTVAKDLS-TGAKSEYSMEIRATDSTKSN 1469

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSG 834
            D RV + V   N   P            ++         V A D D     +++Y+I+  
Sbjct: 1470 DARVRVNVEYKNMYRPEFTKCGKA-TIQENLLKGQLIATVTATDRDQGRNGEVEYKIVPV 1528

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
               +   +N  TG +  +  L+       T+ ++  DG
Sbjct: 1529 GGQDFFTINNKTGEVITTSSLDRETKATYTVIITAEDG 1566



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE-LV 65
            I  +I VLD ND++P F M      V   + +G T   L+A D D G N  + + +E + 
Sbjct: 1065 IDVEITVLDENDNAPFFTMISTLGRVNSNSRAGATAFQLQARDLDSGSNGLIGFQLENIP 1124

Query: 66   TADTLNP 72
            T   +NP
Sbjct: 1125 TLFMINP 1131



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 3/90 (3%)

Query: 1461 GKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLS 1520
            G + IGG++T    +      F GCI+++        L  P    N  +GC     C  +
Sbjct: 3007 GPLQIGGVETDLTFIGITTTGFRGCIRNIIDTEKMYDLRNPIKVVNAPEGCTLAGTCP-N 3065

Query: 1521 ICPPYSKCVTSW--DSSTCTCEAGRVGPQC 1548
             C     C  S     S C C+ G  G  C
Sbjct: 3066 NCNDKGYCEPSLMAGKSMCVCDFGYTGRAC 3095



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 26/74 (35%), Positives = 29/74 (39%), Gaps = 9/74 (12%)

Query: 1479 VGFFEGCIQDVRIGTAQSLLNRPTV---RENVRDGCQSRADCMLSICPPYSKCVTSWDSS 1535
            +G  EGC    R     SL + P V   R+NVR GC     C    C     CV      
Sbjct: 3539 IGDMEGCTATNRF-QGVSLEDSPDVEVRRQNVRKGCP----CAEGFCENGGTCVDG-TPP 3592

Query: 1536 TCTCEAGRVGPQCV 1549
             C C  G  GP CV
Sbjct: 3593 YCLCSPGWTGPTCV 3606


>SB_46477| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 6116

 Score =  351 bits (864), Expect = 4e-96
 Identities = 236/739 (31%), Positives = 360/739 (48%), Gaps = 43/739 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V   N+H+PVF+   Y  S+ E A+ G+ V    A+D D G +  +EY    VT+   
Sbjct: 4867 VHVTAENEHTPVFQFMNYSVSISEWAAVGSPVFDANASDADTGIHGNLEY---YVTSGLN 4923

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               D               F ID  SG +   +SLDRE    Y + +   D+ +   +R 
Sbjct: 4924 GGVD---------------FTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERR 4968

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            ++   + + + D+NDN P F+++ YT ++ E+++      +A++  TD D+G N+   Y+
Sbjct: 4969 AAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMA--SGASVARVATTDRDIGINANHTYS 5026

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I GG+   +FSI   +G ++ +  LDYE   +Y L I A+D GSP       + I + D 
Sbjct: 5027 ITGGDGLGKFSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDT 5086

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  +L+  S+SE    G  ++ V A D D G+NAE+TY++   D      +  T
Sbjct: 5087 NDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSVNST 5146

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
                 G + T   LDRE  A Y LLV A+D G PP++ T                F    
Sbjct: 5147 -----GMIRTIATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSA 5201

Query: 371  YEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            +   + ED P G   + ++A+DAD  DN RL Y I  GNT    +I S  G  L +V   
Sbjct: 5202 FSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGNTDNVVAIESATG-ALYSVG-A 5259

Query: 429  LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
             D ++   Y L + A D+G      T    I I D N+  P F +A Y   V E+ P G 
Sbjct: 5260 FDRERTATYTLAIRAIDAGNPPLFSTITAHIVIIDRNDNTPTFLDADYNFVVTENQPGGL 5319

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            ++  V A D D G +AQ+ Y++         + +   F +NP TG + T   LDRE +  
Sbjct: 5320 SIGHVRAIDIDNGTHAQLVYTIEP-------SPNSNHFTMNPITGGLFTAMALDRENVPY 5372

Query: 547  YLLTVTARDGGV-PS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            Y LTV   D    PS L +TT V I+V+D+NDN P F + ++ A+I E++  G SV++V 
Sbjct: 5373 YRLTVRVTDSAAYPSQLFNTTTVHITVLDLNDNPPAFDKAVFNASIAENSESGASVTRVT 5432

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A+D D   N R+ Y L         F +D A+G +     +D E+V   ++   A D G 
Sbjct: 5433 ASDRDRDANARLTYSLTYNASSPEYFRLDEATGEVFLKSGVDYENVQIIEVTVTAKDDGF 5492

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG-TTIGEIRAHDPDEGPNAVVH 723
            P  S +  + + + D+ND+ PVF +      I  +  +G   I  + A D D GPN+ V 
Sbjct: 5493 PSLSGSTTLRVHVIDLNDNAPVFSATFYETEIRSDHNLGPPAIITLTAIDRDSGPNSAVT 5552

Query: 724  YSIKGGDDSNSFSLETRQG 742
            Y ++       F L+T  G
Sbjct: 5553 YELE--QTQEKFKLDTNSG 5569



 Score =  349 bits (857), Expect = 3e-95
 Identities = 249/762 (32%), Positives = 365/762 (47%), Gaps = 39/762 (5%)

Query: 142  DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201
            D ++   +F    Y+  + E  +      I  +  +D D+G NS + Y II GNT  +F 
Sbjct: 4768 DISEGKGEFVPALYSADISE--ATAAETAIINVTCSDTDLGPNSQLSYEIIRGNTGNKFR 4825

Query: 202  IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            +D+ +  V +   LD++  + Y L +R  D G  SR     + +++   N++ P F    
Sbjct: 4826 LDNHT--VVVAGQLDHDTTKDYSLEVRVSDNGVTSRVTVAVVTVHVTAENEHTPVFQFMN 4883

Query: 262  FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
            +  S+SE   +G  +    A DAD G++  L Y +T     G VD   TID  SG V   
Sbjct: 4884 YSVSISEWAAVGSPVFDANASDADTGIHGNLEYYVT-SGLNGGVD--FTIDKSSGVVAVG 4940

Query: 322  GQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
              LDRET+  Y+L +T  D G+     R+A                 F    Y   + E+
Sbjct: 4941 SSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTTIPEN 5000

Query: 379  EPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
               G  V  +  TD D   N  H Y ITGG+  G+FSI      G+IT    LD++ +  
Sbjct: 5001 MASGASVARVATTDRDIGINANHTYSITGGDGLGKFSIVQST--GVITALPGLDYETKYT 5058

Query: 437  YVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
            Y L+++A D G       A V+I ++D N+  PVF    Y  S+ E    GT V+ V AT
Sbjct: 5059 YYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHAT 5118

Query: 495  DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
            D D GINA+ITYS+   +  +A      QF +N  TG I T   LDRE ++ Y L V A 
Sbjct: 5119 DVDTGINAEITYSI---VGGDA----KNQFSVN-STGMIRTIATLDREDIASYTLLVQAS 5170

Query: 555  DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
            D GVP  ++T  V ++++DVNDN  VF Q  ++A ++EDA VG     + A+DAD G N 
Sbjct: 5171 DRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADSGDNA 5230

Query: 615  RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            R+ Y +      +    I+ A+G + +  A DRE  AT+ L   AID G PP  ST+  H
Sbjct: 5231 RLTYSIQ-SGNTDNVVAIESATGALYSVGAFDRERTATYTLAIRAIDAGNPPLFSTITAH 5289

Query: 675  IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
            I I D ND+ P F      F ++EN P G +IG +RA D D G +A + Y+I+   +SN 
Sbjct: 5290 IVIIDRNDNTPTFLDADYNFVVTENQPGGLSIGHVRAIDIDNGTHAQLVYTIEPSPNSNH 5349

Query: 735  FSLETRQGSDKAELVTMVDLDYESPRKKYELVIR----AASP-PLWNDVRVEILVTDVND 789
            F++    G     L T + LD E+    Y L +R    AA P  L+N   V I V D+ND
Sbjct: 5350 FTMNPITGG----LFTAMALDRENV-PYYRLTVRVTDSAAYPSQLFNTTTVHITVLDLND 5404

Query: 790  NAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRI-LSGNNANLILLNETT 846
            N P         +  ++        RV A   D D   +L Y +  + ++     L+E T
Sbjct: 5405 NPPAFDKAVFNASIAENSESGASVTRVTASDRDRDANARLTYSLTYNASSPEYFRLDEAT 5464

Query: 847  GSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            G + L   ++  NV  +     +  DG   +     L V +I
Sbjct: 5465 GEVFLKSGVDYENVQIIEVTVTAKDDGFPSLSGSTTLRVHVI 5506



 Score =  347 bits (852), Expect = 1e-94
 Identities = 274/918 (29%), Positives = 435/918 (47%), Gaps = 107/918 (11%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  + V   N+++P F   +Y  ++ E    GTTV+ + A+D D G   E+ Y++     
Sbjct: 3425 HVDVIVQALNEYTPSFSQSEYNVTISEATPIGTTVIDIDASDNDSGPQGELTYSM----- 3479

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                P  +              F ID  SG +  +  LD E V  Y +LV ATD     S
Sbjct: 3480 ----PSGSP-------------FYIDSLSGVITLKQGLDYEAVTSYVLLVTATD--GDAS 3520

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
               SS   + V + D+NDN P F+   Y+V + E+ +V  +  I  +  TD+D G N   
Sbjct: 3521 SPKSSMVNVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTS--ILSLTCTDSDSGTNGQF 3578

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLIN 246
            + AII GNT   F+I   +G +++   LD E   +Y LV+RA+D  + S + +T  + + 
Sbjct: 3579 KMAIISGNTGTGFAISD-AGVLTVATALDVETTGAYSLVVRARDQHALSPQESTAAVSVI 3637

Query: 247  IRDVNDNAPRFYTS-LFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTGN 304
            I DVN++ P+F +   +   ++E+ P+G  +  V A D D G V   +TYT+T    +GN
Sbjct: 3638 ITDVNEHTPQFTSGGSYTAVIAEDAPVGSFVTNVTAIDNDLGLVYGVVTYTIT----SGN 3693

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXX 362
             +    I P  G ++    LDRE+   Y L++TA+D  DP  P+S+TAT           
Sbjct: 3694 SEDKFYIRPSDGSIFVKKGLDRESTPSYSLVITASDQ-DPVSPKSSTATLIVTISDVNDN 3752

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSITSQNGR 420
                 P  Y   L E    GT V  L  +D D    +   Y I+ GNT    S+   +G 
Sbjct: 3753 DPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAISSGNT----SLFGVSGN 3808

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            GL+T     D++  + Y+L V+ TD G    RS    + + IT AN Y P F    Y+ +
Sbjct: 3809 GLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGANEYEPAFSQPTYSVT 3868

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
              ED  IG T+  V+ATD+D G +  I++++ +   NE     + +F+I+  +G I   +
Sbjct: 3869 HQEDTAIGVTIATVAATDADHGSDGAISFAIIA--GNE-----EDKFLIDTTSGVIELKR 3921

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE+   Y+LTV ARD G P+ S    V+++VVDVNDN P      +   + E+A VG
Sbjct: 3922 PLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVEVAENASVG 3981

Query: 598  TSVSQVGATDADVGLNGRIHYEL--DPKDREEG------------------SFVIDPASG 637
            ++V ++   D D G N ++ Y +  D  D  +G                   F ++ +SG
Sbjct: 3982 STVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGNTNSDFTLNSSSG 4041

Query: 638  VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
            V+     L+RES   +DL     D GTPP ++  + H   ED++                
Sbjct: 4042 VLTVASQLNRESTVYYDLTVTITDSGTPPLTTLHLQHSLSEDVS---------------- 4085

Query: 698  ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
                +GTT+    A D D+G +  V Y+I  G+ +++F L+   GS    L  +  LDYE
Sbjct: 4086 ----LGTTVFIAHAQDYDDGEHGHVTYAILSGNTADTFLLDKYSGS----LQLLRSLDYE 4137

Query: 758  SPRKKYELVIRAA-----SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP 812
                 Y+L+I A+     S    + + V I V D+NDN P   +     +  +       
Sbjct: 4138 -VASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKPECSETTKHVSLLESVVVGTV 4196

Query: 813  FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
                   D+D +D   L Y+IL+GN      +  + G +TL+  L+  +     + V+V 
Sbjct: 4197 IFSTNCSDSDSSDNALLTYQILTGNAEGKFNVT-SGGEVTLASGLSVEMTSWYHLVVAVR 4255

Query: 871  DGVNEIKAM-MQLSVRLI 887
            D  +  +A+ + L+V ++
Sbjct: 4256 DAGSPSRAVNVSLTVEVL 4273



 Score =  345 bits (847), Expect = 4e-94
 Identities = 270/934 (28%), Positives = 438/934 (46%), Gaps = 89/934 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V+  N+H+PVF    Y  S+ E  + GT++L + ATD D G    V Y++  + A   
Sbjct: 3295 IDVIAVNEHAPVFTSASYAQSIAEDTAIGTSILMVTATDGDNGPQGHVVYSLLPLNAP-- 3352

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ID  SG +  ++SLDRE  A YT+ V A D+    +D  
Sbjct: 3353 -------------------FYIDTISGIIRVKSSLDRETTASYTLTVSAHDKDPVTADVK 3393

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSV---------------------DEDISVTD-N 168
            ++  T+ V++ D NDN P FS   YT+                       + ++++++  
Sbjct: 3394 TANVTVSVDVTDVNDNEPAFSPAHYTLMAVSHVDVIVQALNEYTPSFSQSEYNVTISEAT 3453

Query: 169  PV---IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL 225
            P+   +  I A+D D G    + Y++  G+    F IDSLSG ++L + LDYE V SY L
Sbjct: 3454 PIGTTVIDIDASDNDSGPQGELTYSMPSGS---PFYIDSLSGVITLKQGLDYEAVTSYVL 3510

Query: 226  VIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
            ++ A DG + S +S+   + + ++D NDN P F  +++   + EN  +G SI+ +   D+
Sbjct: 3511 LVTATDGDASSPKSSMVNVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDS 3570

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGD 343
            D G N +    +     +GN      I   +G +  +  LD ET   Y L+V A D    
Sbjct: 3571 DSGTNGQFKMAI----ISGNTGTGFAISD-AGVLTVATALDVETTGAYSLVVRARDQHAL 3625

Query: 344  PPRSATATXXXXXXXXXXXXXXFMP-GQYEVELAEDEPPGTPVVTLTATDADED---NRL 399
             P+ +TA               F   G Y   +AED P G+ V  +TA D D       +
Sbjct: 3626 SPQESTAAVSVIITDVNEHTPQFTSGGSYTAVIAEDAPVGSFVTNVTAIDNDLGLVYGVV 3685

Query: 400  HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS---GGRSDTAMVQ 456
             Y IT GN+  +F I   +G   I V + LD +    Y L ++A+D      +S TA + 
Sbjct: 3686 TYTITSGNSEDKFYIRPSDGS--IFVKKGLDRESTPSYSLVITASDQDPVSPKSSTATLI 3743

Query: 457  INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
            + I+D N+  PV +   Y+ S+ E   IGT+V  ++ +D D+  N   +Y++SS   N +
Sbjct: 3744 VTISDVNDNDPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAISS--GNTS 3801

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-VPSLSDTTDVEISVVDVN 575
            +      F ++   G +TT  L D ET+  Y+L VT  DGG V   S    + + +   N
Sbjct: 3802 L------FGVS-GNGLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGAN 3854

Query: 576  DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
            + EP F Q  Y+    ED  +G +++ V ATDAD G +G I + +     EE  F+ID  
Sbjct: 3855 EYEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAI-IAGNEEDKFLIDTT 3913

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
            SGVI   + LDRES  ++ L  +A D G+P +SS   V + + D+ND+ P          
Sbjct: 3914 SGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVE 3973

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            ++EN+ +G+T+ E+R  D DEG N+ + Y+I    D +    +    +   +     + D
Sbjct: 3974 VAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGNTNSD 4033

Query: 756  YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--- 812
            +        L + A+     + V  ++ VT  +   P +    +  +  +D   +G    
Sbjct: 4034 FTLNSSSGVLTV-ASQLNRESTVYYDLTVTITDSGTPPLTTLHLQHSLSED-VSLGTTVF 4091

Query: 813  FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                  YD      + Y ILSGN A+  LL++ +GS+ L   L+  V     + +  +DG
Sbjct: 4092 IAHAQDYDDGEHGHVTYAILSGNTADTFLLDKYSGSLQLLRSLDYEVASSYKLIIEASDG 4151

Query: 873  VNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906
                    ++SVR  +  + +N   + LND   E
Sbjct: 4152 A-------EVSVRK-SSRITVNIAVIDLNDNKPE 4177



 Score =  338 bits (830), Expect = 5e-92
 Identities = 242/793 (30%), Positives = 379/793 (47%), Gaps = 60/793 (7%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ++    F    Y A + E  ++ T ++ +  +D D+G N+++ Y  E++  +T N   
Sbjct: 4768 DISEGKGEFVPALYSADISEATAAETAIINVTCSDTDLGPNSQLSY--EIIRGNTGNK-- 4823

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                           FR+D  +  ++    LD +    Y++ V+ +D    V+ R++  A
Sbjct: 4824 ---------------FRLDNHT--VVVAGQLDHDTTKDYSLEVRVSDNG--VTSRVT-VA 4863

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
             + V++  +N++ P F    Y+VS+ E  +V  +PV     A+DAD G +  + Y +  G
Sbjct: 4864 VVTVHVTAENEHTPVFQFMNYSVSISEWAAV-GSPVF-DANASDADTGIHGNLEYYVTSG 4921

Query: 195  -NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS---RSNTTQLLINIRDV 250
             N  + F+ID  SG V++  +LD E    Y L I  +D G+     R+   QL I + D 
Sbjct: 4922 LNGGVDFTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDE 4981

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F   ++  ++ EN+  G S+ RV   D D G+NA  TY++T  D  G      +
Sbjct: 4982 NDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINANHTYSITGGDGLGK----FS 5037

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I   +G +     LD ET+  Y L +TA D G P   A A               F P  
Sbjct: 5038 IVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTL 5097

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y   ++E    GT V+ + ATD D   +  + Y I GG+ + +FS+   N  G+I     
Sbjct: 5098 YLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSV---NSTGMIRTIAT 5154

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    Y L V A+D G   +++T  V + I D N+ A VF  + ++A V EDAP+G 
Sbjct: 5155 LDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGF 5214

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
              + +SA+D+D G NA++TYS+ S  ++  VA       I   TGA+ +    DRE  + 
Sbjct: 5215 RFMNISASDADSGDNARLTYSIQSGNTDNVVA-------IESATGALYSVGAFDRERTAT 5267

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y L + A D G P L  T    I ++D NDN P F    Y   + E+   G S+  V A 
Sbjct: 5268 YTLAIRAIDAGNPPLFSTITAHIVIIDRNDNTPTFLDADYNFVVTENQPGGLSIGHVRAI 5327

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D G + ++ Y ++P       F ++P +G + T  ALDRE+V  + L     D    P
Sbjct: 5328 DIDNGTHAQLVYTIEPSP-NSNHFTMNPITGGLFTAMALDRENVPYYRLTVRVTDSAAYP 5386

Query: 667  QS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
                +T  VHI + D+ND+PP F+       I+ENS  G ++  + A D D   NA + Y
Sbjct: 5387 SQLFNTTTVHITVLDLNDNPPAFDKAVFNASIAENSESGASVTRVTASDRDRDANARLTY 5446

Query: 725  SIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRV 780
            S+         F L+   G    E+     +DYE+  +  E+ + A     P L     +
Sbjct: 5447 SLTYNASSPEYFRLDEATG----EVFLKSGVDYENV-QIIEVTVTAKDDGFPSLSGSTTL 5501

Query: 781  EILVTDVNDNAPV 793
             + V D+NDNAPV
Sbjct: 5502 RVHVIDLNDNAPV 5514



 Score =  332 bits (815), Expect = 3e-90
 Identities = 258/827 (31%), Positives = 393/827 (47%), Gaps = 102/827 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+SPV     Y ASV E  + G++VLT+   D DIG N EV Y++  V+ D  
Sbjct: 2772 IAISDVNDNSPVCSQAMYTASVLESVAVGSSVLTVSCPDLDIGANGEVSYSV--VSGDG- 2828

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ++  +G L T + L+ E   RYT+ ++A+D  +P   + 
Sbjct: 2829 -----------------GAFALNSSTGILSTTSPLNYETTMRYTLSIQASDGGTP--GKA 2869

Query: 131  SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S+T  + +++   N+  P F    TY +S+ ED+SV  + ++  + A+DAD G+   + Y
Sbjct: 2870 STTLAV-IDVQGVNEYTPSFIPNNTYELSLAEDLSVGHDVIL--VTASDADAGSQGEVTY 2926

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIR 248
            +I  G+T   F+ID   G + L   LDYE +    L+I A DG   S  S T  L IN+ 
Sbjct: 2927 SITSGDTYGNFAIDRARGLIELRSMLDYELISQIVLIIAATDGDPLSPNSATASLTINVV 2986

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P    +L   +V E+  +G  +  +   D D G+N +LTYT    +  GN ++ 
Sbjct: 2987 DVNDNYPSCNPALLTPAVPESAAVGSMLASLNCSDTDSGLNGQLTYTFVSGNTAGNFNVS 3046

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
                  +G V  +  LD E+   Y L+++ TD G   +S   +              F  
Sbjct: 3047 T-----AGVVSLATALDYESTRLYSLVLSVTDSGPSTKSTQVSIKVTVIAVNEFSPVFTS 3101

Query: 369  G-QYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRFSITSQNGRGLI 423
            G  Y V ++E    GT ++ +TA DAD +   H    Y I  GNT   F + +  G   +
Sbjct: 3102 GGTYAVTVSEHTSLGTELIRVTANDADLNTHAHGMITYSIISGNTGSHFYVATDTGAIHL 3161

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
                    K +R  +   S T  G  +  A V + I+D N+  P      Y A+V EDA 
Sbjct: 3162 -------MKGDRSVIFAHSTTTDGENNVNATVALTISDVNDNDPACSPTSYAATVREDAG 3214

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            +GT+++ V   DSD G N  + +S+++  +N         F I+   G I+T + LD ET
Sbjct: 3215 LGTSLVRVLCLDSDEGNNGLLAFSITAGNTNT-------DFTIDAN-GTISTARALDYET 3266

Query: 544  MSGYLLTVTARDGGVPSLSDTT---DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             + Y LTV +RD   P  S  +   +V I V+ VN++ PVF    Y  +I ED  +GTS+
Sbjct: 3267 TTSYTLTVKSRDSSSPISSQRSVNVEVTIDVIAVNEHAPVFTSASYAQSIAEDTAIGTSI 3326

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              V ATD D G  G + Y L P +     F ID  SG+IR   +LDRE+ A++ L   A 
Sbjct: 3327 LMVTATDGDNGPQGHVVYSLLPLN---APFYIDTISGIIRVKSSLDRETTASYTLTVSAH 3383

Query: 661  DGG---TPPQSSTVIVHIKIEDINDSPPVFES-----------DCLTFYISENSP----- 701
            D        +++ V V + + D+ND+ P F             D +   ++E +P     
Sbjct: 3384 DKDPVTADVKTANVTVSVDVTDVNDNEPAFSPAHYTLMAVSHVDVIVQALNEYTPSFSQS 3443

Query: 702  -----------IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
                       IGTT+ +I A D D GP   + YS+  G   + F +++  G     ++T
Sbjct: 3444 EYNVTISEATPIGTTVIDIDASDNDSGPQGELTYSMPSG---SPFYIDSLSG-----VIT 3495

Query: 751  MVD-LDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAP 792
            +   LDYE+    Y L++ A    AS P  + V V + V D NDN P
Sbjct: 3496 LKQGLDYEAV-TSYVLLVTATDGDASSPKSSMVNVTVTVKDENDNEP 3541



 Score =  327 bits (804), Expect = 7e-89
 Identities = 265/884 (29%), Positives = 415/884 (46%), Gaps = 80/884 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD ND  P F    Y  S+RE  ++GT VL   A D+D G              DTL
Sbjct: 2377 VNVLDVNDE-PQFINSPYSVSIRENLATGTRVLQASAADEDTG--------------DTL 2421

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                +              F I   +G + T + +D E V+ Y++ V  +D    VS+  
Sbjct: 2422 TYSLSGSNHAH--------FSISN-TGVISTASGIDFEVVSSYSLSVAVSDGTVSVSE-- 2470

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + +++ + ND+ P F++  Y  +++E+ S   +  I ++  TD D   + +I ++
Sbjct: 2471 ----PVMISVENLNDS-PVFTDAPYNATINENTSTATS--ILQVSTTDQD---SDSITFS 2520

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
             +G  T   F+I S SG ++    ++YE+  +Y L I+A DG       T    I + D+
Sbjct: 2521 FVGV-TSSDFNIHSSSGIITTAVNINYEKTAAYTLTIQADDGNGGKTLTTAS--ITVTDL 2577

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  P F ++ +   V EN   G S++ V A D D   ++ L Y+++      +    +T
Sbjct: 2578 NDERPTFASASYTGHVVENAASGTSVIVVTATDLDVA-DSTLAYSLSG---ASSSHFNVT 2633

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
             +   G + T+  +D E+   Y L +TA+DG     + T T              F    
Sbjct: 2634 SE---GLISTAAAIDYESLTSYSLTLTASDGAG--NTGTTTINIAVVNVIDNDPVFGSVS 2688

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y     ED   GT V  +TATDAD  + + Y ++G  +   F+I    G  +I+     D
Sbjct: 2689 YSANAFEDSVAGTSVTRITATDADIGDVITYSLSGPESTN-FTINVNTG--VISTNSAFD 2745

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
             + +  Y  T++ATD+G R DTA+V I I+D N+ +PV   A YTASV E   +G++VL 
Sbjct: 2746 RESKDTYTFTITATDTGSRPDTAIVTIAISDVNDNSPVCSQAMYTASVLESVAVGSSVLT 2805

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            VS  D D+G N +++YS+   +S +  A     F +N  TG ++T   L+ ET   Y L+
Sbjct: 2806 VSCPDLDIGANGEVSYSV---VSGDGGA-----FALNSSTGILSTTSPLNYETTMRYTLS 2857

Query: 551  VTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVSQVGATDAD 609
            + A DGG P  + TT   I V  VN+  P F     Y  ++ ED  VG  V  V A+DAD
Sbjct: 2858 IQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVGHDVILVTASDAD 2917

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-TPPQS 668
             G  G + Y +   D   G+F ID A G+I     LD E ++   L   A DG    P S
Sbjct: 2918 AGSQGEVTYSITSGD-TYGNFAIDRARGLIELRSMLDYELISQIVLIIAATDGDPLSPNS 2976

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            +T  + I + D+ND+ P      LT  + E++ +G+ +  +   D D G N  + Y+   
Sbjct: 2977 ATASLTINVVDVNDNYPSCNPALLTPAVPESAAVGSMLASLNCSDTDSGLNGQLTYTFVS 3036

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVT-- 785
            G+ + +F++ T   +    L T   LDYES R  Y LV+    S P     +V I VT  
Sbjct: 3037 GNTAGNFNVST---AGVVSLATA--LDYESTR-LYSLVLSVTDSGPSTKSTQVSIKVTVI 3090

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT----DKLQYRILSGNNANLI 840
             VN+ +PV            +   +G    RV A DAD+       + Y I+SGN  +  
Sbjct: 3091 AVNEFSPVFTSGGTYAVTVSEHTSLGTELIRVTANDADLNTHAHGMITYSIISGNTGSHF 3150

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
             +   TG++ L     + +   +T     TDG N + A + L++
Sbjct: 3151 YVATDTGAIHLMKGDRSVIFAHST----TTDGENNVNATVALTI 3190



 Score =  323 bits (793), Expect = 1e-87
 Identities = 251/801 (31%), Positives = 398/801 (49%), Gaps = 80/801 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V++  D+ PVF    Y A+  E + +GT+V  + ATD DIG         +++T    
Sbjct: 2672 IAVVNVIDNDPVFGSVSYSANAFEDSVAGTSVTRITATDADIG---------DVITYSLS 2722

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             PE                F I+  +G + T ++ DRE    YT  + ATD  S      
Sbjct: 2723 GPESTN-------------FTINVNTGVISTNSAFDRESKDTYTFTITATDTGSR----- 2764

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              TA + + I D NDN P  S+  YT SV E ++V  +  +  +   D D+GAN  + Y+
Sbjct: 2765 PDTAIVTIAISDVNDNSPVCSQAMYTASVLESVAVGSS--VLTVSCPDLDIGANGEVSYS 2822

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            ++ G+    F+++S +G +S    L+YE    Y L I+A DGG+P +++TT  +I+++ V
Sbjct: 2823 VVSGDGGA-FALNSSTGILSTTSPLNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGV 2881

Query: 251  NDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            N+  P F   + ++ S++E++ +G+ ++ V A DAD G   E+TY++T  D  GN     
Sbjct: 2882 NEYTPSFIPNNTYELSLAEDLSVGHDVILVTASDADAGSQGEVTYSITSGDTYGN----F 2937

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXFM 367
             ID   G +     LD E  ++  L++ ATDG DP  P SATA+                
Sbjct: 2938 AIDRARGLIELRSMLDYELISQIVLIIAATDG-DPLSPNSATASLTINVVDVNDNYPSCN 2996

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
            P      + E    G+ + +L  +D D   + +L Y    GNT G F++++    G++++
Sbjct: 2997 PALLTPAVPESAAVGSMLASLNCSDTDSGLNGQLTYTFVSGNTAGNFNVSTA---GVVSL 3053

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENA-PYTASVFEDA 482
            A  LD++  R Y L +S TDSG  + +  V I +T    N ++PVF +   Y  +V E  
Sbjct: 3054 ATALDYESTRLYSLVLSVTDSGPSTKSTQVSIKVTVIAVNEFSPVFTSGGTYAVTVSEHT 3113

Query: 483  PIGTTVLVVSATDSDVGINAQ--ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
             +GT ++ V+A D+D+  +A   ITYS+   IS    +H    F +   TGAI   K  D
Sbjct: 3114 SLGTELIRVTANDADLNTHAHGMITYSI---ISGNTGSH----FYVATDTGAIHLMKG-D 3165

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            R  +  +  T      G  +++ T  V +++ DVNDN+P      Y A + EDA +GTS+
Sbjct: 3166 RSVIFAHSTTTD----GENNVNAT--VALTISDVNDNDPACSPTSYAATVREDAGLGTSL 3219

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
             +V   D+D G NG + + +   +     F ID A+G I T +ALD E+  ++ L   + 
Sbjct: 3220 VRVLCLDSDEGNNGLLAFSITAGNTNT-DFTID-ANGTISTARALDYETTTSYTLTVKSR 3277

Query: 661  DGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            D  +P    +S  V V I +  +N+  PVF S      I+E++ IGT+I  + A D D G
Sbjct: 3278 DSSSPISSQRSVNVEVTIDVIAVNEHAPVFTSASYAQSIAEDTAIGTSILMVTATDGDNG 3337

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-ASPPLWN 776
            P   V YS+     +  F ++T  G  + +      LD E+    Y L + A    P+  
Sbjct: 3338 PQGHVVYSLL--PLNAPFYIDTISGIIRVK----SSLDRET-TASYTLTVSAHDKDPVTA 3390

Query: 777  DVR-----VEILVTDVNDNAP 792
            DV+     V + VTDVNDN P
Sbjct: 3391 DVKTANVTVSVDVTDVNDNEP 3411



 Score =  291 bits (714), Expect = 5e-78
 Identities = 235/798 (29%), Positives = 383/798 (47%), Gaps = 78/798 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND  P F    Y   V E A+SGT+V+ + ATD D+  ++ + Y++   ++   
Sbjct: 2572 ITVTDLNDERPTFASASYTGHVVENAASGTSVIVVTATDLDVA-DSTLAYSLSGASSSHF 2630

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                         G + T A++D E +  Y++ + A+D A       
Sbjct: 2631 NVTS---------------------EGLISTAAAIDYESLTSYSLTLTASDGAGN----- 2664

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + T TI++ +++  DN P F   +Y+ +  ED SV    V  +I ATDAD+G    I Y+
Sbjct: 2665 TGTTTINIAVVNVIDNDPVFGSVSYSANAFED-SVAGTSV-TRITATDADIG--DVITYS 2720

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            + G  +   F+I+  +G +S     D E   +Y   I A D GS  R +T  + I I DV
Sbjct: 2721 LSGPEST-NFTINVNTGVISTNSAFDRESKDTYTFTITATDTGS--RPDTAIVTIAISDV 2777

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN+P    +++  SV E+V +G S++ V   D D G N E++Y++   D  G       
Sbjct: 2778 NDNSPVCSQAMYTASVLESVAVGSSVLTVSCPDLDIGANGEVSYSVVSGD--GGA---FA 2832

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ++  +G + T+  L+ ET  +Y L + A+DGG P +++T                F+P  
Sbjct: 2833 LNSSTGILSTTSPLNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNN 2892

Query: 371  -YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             YE+ LAED   G  V+ +TA+DAD  ++  + Y IT G+T G F+I     RGLI +  
Sbjct: 2893 TYELSLAEDLSVGHDVILVTASDADAGSQGEVTYSITSGDTYGNFAI--DRARGLIELRS 2950

Query: 428  PLDFKQERRYVLTVSATDS---GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
             LD++   + VL ++ATD       S TA + IN+ D N+  P    A  T +V E A +
Sbjct: 2951 MLDYELISQIVLIIAATDGDPLSPNSATASLTINVVDVNDNYPSCNPALLTPAVPESAAV 3010

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G+ +  ++ +D+D G+N Q+TY+  S   N A       F ++   G ++    LD E+ 
Sbjct: 3011 GSMLASLNCSDTDSGLNGQLTYTFVS--GNTA-----GNFNVST-AGVVSLATALDYEST 3062

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-LYTANIMEDALVGTSVSQV 603
              Y L ++  D G  + S    ++++V+ VN+  PVF     Y   + E   +GT + +V
Sbjct: 3063 RLYSLVLSVTDSGPSTKSTQVSIKVTVIAVNEFSPVFTSGGTYAVTVSEHTSLGTELIRV 3122

Query: 604  GATDADVGLN--GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             A DAD+  +  G I Y +         F +   +G I   K  DR  +  H   +   D
Sbjct: 3123 TANDADLNTHAHGMITYSII-SGNTGSHFYVATDTGAIHLMKG-DRSVIFAH---STTTD 3177

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G     +    V + I D+ND+ P          + E++ +GT++  +   D DEG N +
Sbjct: 3178 G---ENNVNATVALTISDVNDNDPACSPTSYAATVREDAGLGTSLVRVLCLDSDEGNNGL 3234

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPPLWN--- 776
            + +SI  G+ +  F+++         + T   LDYE+    Y L +  R +S P+ +   
Sbjct: 3235 LAFSITAGNTNTDFTIDA-----NGTISTARALDYET-TTSYTLTVKSRDSSSPISSQRS 3288

Query: 777  -DVRVEILVTDVNDNAPV 793
             +V V I V  VN++APV
Sbjct: 3289 VNVEVTIDVIAVNEHAPV 3306



 Score =  282 bits (692), Expect = 2e-75
 Identities = 248/894 (27%), Positives = 409/894 (45%), Gaps = 86/894 (9%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++  + V D ND+ P F    Y   + E  + GT++L+L  TD D G N   ++ + +++
Sbjct: 3527 VNVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTNG--QFKMAIIS 3584

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             +T                + D       +G L    +LD E    Y+++V+A DQ + +
Sbjct: 3585 GNT-----------GTGFAISD-------AGVLTVATALDVETTGAYSLVVRARDQHA-L 3625

Query: 127  SDRLSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVG-AN 184
            S +  STA + V I D N++ PQF S  +YT  + ED  V     +  + A D D+G   
Sbjct: 3626 SPQ-ESTAAVSVIITDVNEHTPQFTSGGSYTAVIAEDAPV--GSFVTNVTAIDNDLGLVY 3682

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA--QDGGSPSRSNTTQ 242
              + Y I  GN++ +F I    G + + K LD E   SY LVI A  QD  SP +S+T  
Sbjct: 3683 GVVTYTITSGNSEDKFYIRPSDGSIFVKKGLDRESTPSYSLVITASDQDPVSP-KSSTAT 3741

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            L++ I DVNDN P     ++ +S+ E+V IG S+ ++   D D   N   +Y ++    +
Sbjct: 3742 LIVTISDVNDNDPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAIS----S 3797

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXX 361
            GN  L   +   +G V T G  D ET   Y L+VT TDGG    RS              
Sbjct: 3798 GNTSL-FGVS-GNGLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGANE 3855

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                F    Y V   ED   G  + T+ ATDAD   D  + + I  GN   +F I + + 
Sbjct: 3856 YEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAIIAGNEEDKFLIDTTS- 3914

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G+I + +PLD +    Y+LTV A D G   +S  A V + + D N+ AP      +   
Sbjct: 3915 -GVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVE 3973

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--------------ISNEAVAHHDQQ 523
            V E+A +G+TVL +   D D G N+Q+TY+++++              +  ++  + +  
Sbjct: 3974 VAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGNTNSD 4033

Query: 524  FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
            F +N  +G +T    L+RE+   Y LTVT  D G P L+ T  ++ S             
Sbjct: 4034 FTLNSSSGVLTVASQLNRESTVYYDLTVTITDSGTPPLT-TLHLQHS------------- 4079

Query: 584  QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
                  + ED  +GT+V    A D D G +G + Y +   +  + +F++D  SG ++  +
Sbjct: 4080 ------LSEDVSLGTTVFIAHAQDYDDGEHGHVTYAILSGNTAD-TFLLDKYSGSLQLLR 4132

Query: 644  ALDRESVATHDLKAVAIDGG--TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
            +LD E  +++ L   A DG   +  +SS + V+I + D+ND+ P          + E+  
Sbjct: 4133 SLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKPECSETTKHVSLLESVV 4192

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
            +GT I      D D   NA++ Y I  G+    F++ +     +  L + + ++  S   
Sbjct: 4193 VGTVIFSTNCSDSDSSDNALLTYQILTGNAEGKFNVTS---GGEVTLASGLSVEMTSWYH 4249

Query: 762  KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF---GRVP 817
                V  A SP    +V + + V  VN+  P       +++ N  +   +G      +V 
Sbjct: 4250 LVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDLYSLNVFENVTLGTIVFQAQVQ 4309

Query: 818  AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
              D  +   L++ ++SGN+     L  ++G + L   L+       ++ V V D
Sbjct: 4310 DNDTGLHGTLRFSLVSGNDQGCFYLEPSSGMLVLVSPLDRETVDHYSVMVKVED 4363



 Score =  280 bits (687), Expect = 1e-74
 Identities = 260/862 (30%), Positives = 397/862 (46%), Gaps = 87/862 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V+D ND +PV     Y A + E  SSG  V  + A+DQD              +ADT+
Sbjct: 1985 VTVVDQND-TPVLTGSPYTARIEENLSSGGVVAHVVASDQD--------------SADTM 2029

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N   +              F I   +G + +   LD E V+ YT+ V+ TD  +  S   
Sbjct: 2030 NYTLSGTNSAH--------FSISS-AGVITSARVLDYESVSAYTLGVQVTDGTATAS--- 2077

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                T+ V ++D ND  P FS  T+T  V E+ +      +  + ATDAD G    + Y 
Sbjct: 2078 ---TTVTVTVVDANDA-PVFSNSTFTAQVSENDA---GAAVCTVSATDADSGPADTLTYT 2130

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            + G ++  QFS+ + +G V+L   LDYE+   + L +R  DG   + S  T L I +++ 
Sbjct: 2131 LYGASSS-QFSLHASTGVVTLSNVLDYEEASQHVLTVRVSDGRGGTVS--TSLTIKVQNQ 2187

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  P F  + +  S+ EN+  G S+    A D D G     TY+++     G      T
Sbjct: 2188 ND-PPVFRGTPYTTSIDENLSAGSSVFVAIATDEDNGDTC--TYSIS-----GVNSSDFT 2239

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +   +G + T   LD E    Y L VT TD      S+ +               F+   
Sbjct: 2240 MASATGILTTLKVLDFEQLNSYSLTVTVTDS----TSSVSQPITITVSDVNDSPGFLDAP 2295

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y + + E+    + + T++A+D D D  L Y +TG    G    T  +  GL+T+A+ L+
Sbjct: 2296 YSISVQENSINAS-LCTVSASDEDNDT-LSYSLTGS---GASYFTIHSATGLVTLAKSLN 2350

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
            ++    + LTV  +D  G S+T+ + +N+ D N+  P F N+PY+ S+ E+   GT VL 
Sbjct: 2351 YEGSSMFSLTVIVSDVQGASNTSTLTVNVLDVND-EPQFINSPYSVSIRENLATGTRVLQ 2409

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
             SA D D G    +TYSLS   SN A       F I+  TG I+T   +D E +S Y L+
Sbjct: 2410 ASAADEDTG--DTLTYSLSG--SNHA------HFSIS-NTGVISTASGIDFEVVSSYSLS 2458

Query: 551  VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
            V   DG V S+S+   V ISV ++ND+ PVF    Y A I E+    TS+ QV  TD D 
Sbjct: 2459 VAVSDGTV-SVSE--PVMISVENLNDS-PVFTDAPYNATINENTSTATSILQVSTTDQD- 2513

Query: 611  GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
              +  I +           F I  +SG+I T   ++ E  A + L   A DG      +T
Sbjct: 2514 --SDSITFSF--VGVTSSDFNIHSSSGIITTAVNINYEKTAAYTLTIQADDGNGGKTLTT 2569

Query: 671  VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
                I + D+ND  P F S   T ++ EN+  GT++  + A D D   ++ + YS+ G  
Sbjct: 2570 --ASITVTDLNDERPTFASASYTGHVVENAASGTSVIVVTATDLDVA-DSTLAYSLSGAS 2626

Query: 731  DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVND 789
             S+ F++ T +G     + T   +DYES    Y L + A+          + I V +V D
Sbjct: 2627 SSH-FNV-TSEGL----ISTAAAIDYES-LTSYSLTLTASDGAGNTGTTTINIAVVNVID 2679

Query: 790  NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849
            N PV        N ++D        R+ A DAD+ D + Y  LSG  +    +N  TG +
Sbjct: 2680 NDPVFGSVSYSANAFEDSVAGTSVTRITATDADIGDVITYS-LSGPESTNFTINVNTGVI 2738

Query: 850  TLSPQLNTNVPKLATMEVSVTD 871
            + +   +       T  ++ TD
Sbjct: 2739 STNSAFDRESKDTYTFTITATD 2760



 Score =  279 bits (685), Expect = 2e-74
 Identities = 264/880 (30%), Positives = 411/880 (46%), Gaps = 97/880 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND +P+     Y AS+ E A  GT V+   ATD D G              DT+
Sbjct: 492  ITVTDAND-APISVSASYSASIEEDAPVGTNVIQTSATDVDSG--------------DTI 536

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +   +              F I G +G + T  SLD E  + Y++ V   D        L
Sbjct: 537  SYSLSGSAH----------FSITG-TGLIKTAESLDYETTSSYSLTVSFFDGT------L 579

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S T  + +++ + ND  P      YT SV E   V     +  + ATDAD      + Y+
Sbjct: 580  SVTKAVSISVTNKNDA-PVLPSSPYTASVSEGSLV--GTAVYDVNATDAD---GDTLTYS 633

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            + G  +   FSI S +G V+  K LDYE V SY L IR  DG        T L + I + 
Sbjct: 634  LYGAGSS-SFSISSATGVVTTAKALDYEAVTSYTLTIRVTDGNGGITE--TSLTVTITNS 690

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND+ P+F ++ +  +V EN+  G S++ V A D D G    LTY+++     G  +   +
Sbjct: 691  NDS-PQFLSTPYNTAVDENLGTGTSVISVSAIDQDSGNT--LTYSLS-----GTNNAHFS 742

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I   SG V T+  LD E  + Y L V+ +DG         T              F    
Sbjct: 743  ISSASGLVTTAQALDHEAVSSYSLTVSVSDG----TVTVTTALVITVTNRNDAPAFSNAP 798

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y   +AE+   G+ V T++ATD D  + + Y I+G  + G FSI S  G  ++T+A+ L+
Sbjct: 799  YSASVAENNA-GSAVYTVSATDEDSGDTMTYFISGTGS-GDFSIDSSTG--VVTLARALN 854

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
            ++    Y L++   D  G SD+  + I +TDAN+ APVF + PY A + E   IGT VL 
Sbjct: 855  YEDTTYYSLSILVLDGKGESDSTNLNITVTDAND-APVFLSTPYAAHISEGVAIGTNVLK 913

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
             +ATD D   +  +TY+L+   S    AH    F ++  TG I+T  +LDRE++S Y LT
Sbjct: 914  ATATDQDT--SDTLTYALTGTNS----AH----FAVS-STGMISTAHVLDRESVSSYSLT 962

Query: 551  VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
            ++  DG   + + T  V I+VV+ ND  PVF    Y++ + E      +V    ATD D 
Sbjct: 963  LSVSDG---TANVTQGVSITVVNAND-VPVFTGAPYSSTVAEGD-AAAAVYTASATDGD- 1016

Query: 611  GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
                 + + L        SF ++P++GVI    AL+ E+   + L   A DG     ++T
Sbjct: 1017 --GDTLVFSLSGTGST--SFSMNPSTGVITLTAALNYETSPAYSLTIRADDGNGGVATTT 1072

Query: 671  VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
            +  +I + + NDSP VF     +  ++EN PIGTT+ ++ A D D      + YS+ G +
Sbjct: 1073 L--NITVTNQNDSP-VFSGTPFSATLTENDPIGTTVLKVIAIDEDSAD--TLSYSLSGSN 1127

Query: 731  DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790
             ++ F++    GS    + T   LD E+    Y L +  +      +  + + + D ND 
Sbjct: 1128 SAH-FAI----GSSTGVITTAQLLDRETV-NSYSLTVSVSDGTATVNQALSVTINDAND- 1180

Query: 791  APVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849
            AP+  +    +N    +    G    V A DAD +D + Y I  G+ ++   ++ ++G +
Sbjct: 1181 APLFTNAP--YNATVNENAGSGSVYTVSATDAD-SDVIAYSIY-GHGSDKFSIHSSSGLV 1236

Query: 850  TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
            TL+  ++        + V   D  N   A   L V ++ +
Sbjct: 1237 TLASAVDFETKSSFVLTVQAAD-TNGAIATTSLYVDVVNQ 1275



 Score =  277 bits (678), Expect = 1e-73
 Identities = 220/740 (29%), Positives = 341/740 (46%), Gaps = 86/740 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ PV +   Y  S+ E  + GT+V  L  +D+D+  N    Y I   + +T 
Sbjct: 3744 VTISDVNDNDPVCDPVVYSKSLVESVAIGTSVAQLACSDRDLVPNVVSSYAIS--SGNT- 3800

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F + G +G + T    D E V  Y ++V  TD    V+ R 
Sbjct: 3801 -----------------SLFGVSG-NGLVTTLGLFDYETVKSYILVVTVTD-GGLVTQR- 3840

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+   I V I   N+  P FS+ TY+V+  ED ++     IA + ATDAD G++ AI +A
Sbjct: 3841 STQVAISVQITGANEYEPAFSQPTYSVTHQEDTAI--GVTIATVAATDADHGSDGAISFA 3898

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            II GN + +F ID+ SG + L + LD E   SY L + A+D GSP++S+   + + + DV
Sbjct: 3899 IIAGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDV 3958

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT------------- 297
            NDNAP    +     V+EN  +G +++ ++  D DEG N++LTY +T             
Sbjct: 3959 NDNAPNCSVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDND 4018

Query: 298  ----DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
                D D  GN +   T++  SG +  + QL+RE+   Y L VT TD G PP +      
Sbjct: 4019 GDAVDCDSEGNTNSDFTLNSSSGVLTVASQLNRESTVYYDLTVTITDSGTPPLTTL---- 4074

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGR 411
                              +  L+ED   GT V    A D D+    H  Y I  GNT   
Sbjct: 4075 ----------------HLQHSLSEDVSLGTTVFIAHAQDYDDGEHGHVTYAILSGNTADT 4118

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAP 467
            F +   +G   + + + LD++    Y L + A+D    S  +S    V I + D N+  P
Sbjct: 4119 FLLDKYSGS--LQLLRSLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKP 4176

Query: 468  VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
                     S+ E   +GT +   + +DSD   NA +TY + +        + + +F + 
Sbjct: 4177 ECSETTKHVSLLESVVVGTVIFSTNCSDSDSSDNALLTYQILT-------GNAEGKFNVT 4229

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ--QL 585
               G +T    L  E  S Y L V  RD G PS +    + + V+ VN+  P F     L
Sbjct: 4230 -SGGEVTLASGLSVEMTSWYHLVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDL 4288

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
            Y+ N+ E+  +GT V Q    D D GL+G + + L     ++G F ++P+SG++     L
Sbjct: 4289 YSLNVFENVTLGTIVFQAQVQDNDTGLHGTLRFSL-VSGNDQGCFYLEPSSGMLVLVSPL 4347

Query: 646  DRESVATHDLKAVAIDGG-TPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            DRE+V  + +     D   + P  +SS V V I + D+ND+ P       +  ISE    
Sbjct: 4348 DRETVDHYSVMVKVEDSSQSDPDVRSSNVTVAITVLDVNDNDPECVPALYSADISEGK-- 4405

Query: 703  GTTIGEIRAHDPDEGPNAVV 722
            G  +  + + D  EG    V
Sbjct: 4406 GEFVPALYSADISEGKGEFV 4425



 Score =  271 bits (664), Expect = 6e-72
 Identities = 232/812 (28%), Positives = 370/812 (45%), Gaps = 91/812 (11%)

Query: 13   VLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            + D N+H+P F     Y A + E A  G+ V  + A D D+G    + Y +   T  + N
Sbjct: 3638 ITDVNEHTPQFTSGGSYTAVIAEDAPVGSFVTNVTAIDNDLG----LVYGVVTYTITSGN 3693

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
             ED               F I    G++  +  LDRE    Y++++ A+DQ  PVS + S
Sbjct: 3694 SEDK--------------FYIRPSDGSIFVKKGLDRESTPSYSLVITASDQ-DPVSPK-S 3737

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            STAT+ V I D NDN P      Y+ S+ E +++  +  +A++  +D D+  N    YAI
Sbjct: 3738 STATLIVTISDVNDNDPVCDPVVYSKSLVESVAIGTS--VAQLACSDRDLVPNVVSSYAI 3795

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDV 250
              GNT + F +   +G V+ +   DYE V+SY LV+   DGG  + RS    + + I   
Sbjct: 3796 SSGNTSL-FGVSG-NGLVTTLGLFDYETVKSYILVVTVTDGGLVTQRSTQVAISVQITGA 3853

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            N+  P F    +  +  E+  IG +I  V A DAD G +  +++ +      GN +    
Sbjct: 3854 NEYEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAII----AGNEEDKFL 3909

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ID  SG +     LDRE+   Y L V A D G P +S+ A+                   
Sbjct: 3910 IDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTA 3969

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---------------------GN 407
            + VE+AE+   G+ V+ L   D DE  +++L Y IT                      GN
Sbjct: 3970 HVVEVAENASVGSTVLELRCEDVDEGANSQLTYNITTDKDDDGDGDDNDGDAVDCDSEGN 4029

Query: 408  TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467
            T   F++ S +G  ++TVA  L+ +    Y LTV+ TDSG                   P
Sbjct: 4030 TNSDFTLNSSSG--VLTVASQLNRESTVYYDLTVTITDSG------------------TP 4069

Query: 468  VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
                     S+ ED  +GTTV +  A D D G +  +TY++ S   N A       F+++
Sbjct: 4070 PLTTLHLQHSLSEDVSLGTTVFIAHAQDYDDGEHGHVTYAILS--GNTA-----DTFLLD 4122

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQL 585
              +G++   + LD E  S Y L + A DG   S+  S    V I+V+D+NDN+P   +  
Sbjct: 4123 KYSGSLQLLRSLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNKPECSETT 4182

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
               +++E  +VGT +     +D+D   N  + Y++      EG F +  + G +     L
Sbjct: 4183 KHVSLLESVVVGTVIFSTNCSDSDSSDNALLTYQI-LTGNAEGKFNVT-SGGEVTLASGL 4240

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES--DCLTFYISENSPIG 703
              E  + + L     D G+P ++  V + +++  +N+  P F +  D  +  + EN  +G
Sbjct: 4241 SVEMTSWYHLVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDLYSLNVFENVTLG 4300

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD---LDYESPR 760
            T + + +  D D G +  + +S+  G+D   F LE   G     LV+ +D   +D+ S  
Sbjct: 4301 TIVFQAQVQDNDTGLHGTLRFSLVSGNDQGCFYLEPSSG--MLVLVSPLDRETVDHYSVM 4358

Query: 761  KKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
             K E   ++      ++V V I V DVNDN P
Sbjct: 4359 VKVEDSSQSDPDVRSSNVTVAITVLDVNDNDP 4390



 Score =  263 bits (645), Expect = 1e-69
 Identities = 245/856 (28%), Positives = 396/856 (46%), Gaps = 94/856 (10%)

Query: 18   DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77
            + +P F +  Y   + E + +GT ++T+ A+D D G              DT+    +  
Sbjct: 302  NEAPSFALASYSGRIHENSVNGTDIITVTASDVDSG--------------DTITYSLSGS 347

Query: 78   XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137
                       V  + G         SLD E    YT+ + ATD        L+ TAT+ 
Sbjct: 348  GSSSFSALTTGVIEVSG---------SLDFEATPTYTLTLTATDTGG-----LTDTATLT 393

Query: 138  VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
            +++ + N++ P F+  +Y  SV E+ +      +  + ATD DVG  +++ Y++ G  + 
Sbjct: 394  ISVDNVNES-PVFTSASYAASVAENDAAAS---VVTVAATDPDVG--NSVTYSLTGSGSS 447

Query: 198  MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
              F++   SG V L + LDYE   +Y L + A DG       TT L I + D ND AP  
Sbjct: 448  -HFTVHPTSGVVILTQALDYETKPTYSLTVAASDG--QGGLATTSLTITVTDAND-APIS 503

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
             ++ +  S+ E+ P+G ++++  A D D G    ++Y++     +G+    IT    +G 
Sbjct: 504  VSASYSASIEEDAPVGTNVIQTSATDVDSG--DTISYSL-----SGSAHFSIT---GTGL 553

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELA 376
            + T+  LD ET + Y L V+  DG     + + T               +P   Y   ++
Sbjct: 554  IKTAESLDYETTSSYSLTVSFFDG-----TLSVTKAVSISVTNKNDAPVLPSSPYTASVS 608

Query: 377  EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
            E    GT V  + ATDAD D  L Y + G  +   FSI+S    G++T A+ LD++    
Sbjct: 609  EGSLVGTAVYDVNATDADGDT-LTYSLYGAGS-SSFSISS--ATGVVTTAKALDYEAVTS 664

Query: 437  YVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            Y LT+  TD  G      + + IT++N+ +P F + PY  +V E+   GT+V+ VSA D 
Sbjct: 665  YTLTIRVTDGNGGITETSLTVTITNSND-SPQFLSTPYNTAVDENLGTGTSVISVSAIDQ 723

Query: 497  DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
            D G    +TYSLS   +N A       F I+  +G +TT + LD E +S Y LTV+  DG
Sbjct: 724  DSG--NTLTYSLSG--TNNA------HFSISSASGLVTTAQALDHEAVSSYSLTVSVSDG 773

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
               +++ TT + I+V + ND  P F    Y+A++ E+   G++V  V ATD D G    +
Sbjct: 774  ---TVTVTTALVITVTNRND-APAFSNAPYSASVAENN-AGSAVYTVSATDEDSG--DTM 826

Query: 617  HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
             Y +       G F ID ++GV+   +AL+ E    + L  + +DG    +S +  ++I 
Sbjct: 827  TYFI--SGTGSGDFSIDSSTGVVTLARALNYEDTTYYSLSILVLDG--KGESDSTNLNIT 882

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
            + D ND+ PVF S     +ISE   IGT +  ++A   D+  +  + Y++  G +S  F+
Sbjct: 883  VTDANDA-PVFLSTPYAAHISEGVAIGTNV--LKATATDQDTSDTLTYALT-GTNSAHFA 938

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796
            +     S    + T   LD ES    Y L +  +         V I V + ND  PV   
Sbjct: 939  V-----SSTGMISTAHVLDRESV-SSYSLTLSVSDGTANVTQGVSITVVNAND-VPVFTG 991

Query: 797  FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
                 +   +           A D D  D L +  LSG  +    +N +TG +TL+  LN
Sbjct: 992  AP-YSSTVAEGDAAAAVYTASATDGD-GDTLVFS-LSGTGSTSFSMNPSTGVITLTAALN 1048

Query: 857  TNVPKLATMEVSVTDG 872
                   ++ +   DG
Sbjct: 1049 YETSPAYSLTIRADDG 1064



 Score =  257 bits (630), Expect = 8e-68
 Identities = 234/728 (32%), Positives = 347/728 (47%), Gaps = 60/728 (8%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P F    Y+ +V+E++++        I ATD+D     AI  +II      +   D    
Sbjct: 206 PVFGSAAYSGTVNENVAIDTTVSGFTISATDSD---GQAITISIISSPGPFKLKSDGTK- 261

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            ++  +++D+E   SY L I+A  GG    +  T   I I ++N+ AP F  + +   + 
Sbjct: 262 ILTNGESIDFETTSSYTLTIQALAGGETDNATVT---ITIGNINE-APSFALASYSGRIH 317

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN   G  I+ V A D D G    +TY+++    +    L       +G +  SG LD E
Sbjct: 318 ENSVNGTDIITVTASDVDSGDT--ITYSLSGSGSSSFSALT------TGVIEVSGSLDFE 369

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
               Y L +TATD G    +AT T              F    Y   +AE++   + VVT
Sbjct: 370 ATPTYTLTLTATDTGGLTDTATLTISVDNVNESPV---FTSASYAASVAENDAAAS-VVT 425

Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
           + ATD D  N + Y +TG    G    T     G++ + Q LD++ +  Y LTV+A+D  
Sbjct: 426 VAATDPDVGNSVTYSLTGS---GSSHFTVHPTSGVVILTQALDYETKPTYSLTVAASDGQ 482

Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
           G   T  + I +TDAN+ AP+  +A Y+AS+ EDAP+GT V+  SATD D G    I+YS
Sbjct: 483 GGLATTSLTITVTDAND-APISVSASYSASIEEDAPVGTNVIQTSATDVDSG--DTISYS 539

Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
           LS        AH    F I   TG I T + LD ET S Y LTV+  DG   +LS T  V
Sbjct: 540 LSGS------AH----FSIT-GTGLIKTAESLDYETTSSYSLTVSFFDG---TLSVTKAV 585

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            ISV + ND  PV     YTA++ E +LVGT+V  V ATDAD      + Y L       
Sbjct: 586 SISVTNKND-APVLPSSPYTASVSEGSLVGTAVYDVNATDAD---GDTLTYSL--YGAGS 639

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
            SF I  A+GV+ T KALD E+V ++ L     DG      +++ V   I + NDSP  F
Sbjct: 640 SSFSISSATGVVTTAKALDYEAVTSYTLTIRVTDGNGGITETSLTV--TITNSNDSPQ-F 696

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
            S      + EN   GT++  + A D D G N +  YS+ G ++++ FS+ +  G     
Sbjct: 697 LSTPYNTAVDENLGTGTSVISVSAIDQDSG-NTLT-YSLSGTNNAH-FSISSASGL---- 749

Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
           + T   LD+E+    Y L +  +   +     + I VT+ ND AP   +     +  ++ 
Sbjct: 750 VTTAQALDHEAV-SSYSLTVSVSDGTVTVTTALVITVTNRND-APAFSNAPYSASVAENN 807

Query: 808 FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                +  V A D D  D + Y  +SG  +    ++ +TG +TL+  LN       ++ +
Sbjct: 808 AGSAVY-TVSATDEDSGDTMTY-FISGTGSGDFSIDSSTGVVTLARALNYEDTTYYSLSI 865

Query: 868 SVTDGVNE 875
            V DG  E
Sbjct: 866 LVLDGKGE 873



 Score =  256 bits (627), Expect = 2e-67
 Identities = 261/873 (29%), Positives = 400/873 (45%), Gaps = 95/873 (10%)

Query: 14   LDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPE 73
            +D  + SPVF    Y ASV E   +  +V+T+ ATD D+G +  V Y++           
Sbjct: 396  VDNVNESPVFTSASYAASVAEN-DAAASVVTVAATDPDVGNS--VTYSL----------- 441

Query: 74   DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133
                            F +   SG ++   +LD E    Y++ V A+D    +     +T
Sbjct: 442  ---------TGSGSSHFTVHPTSGVVILTQALDYETKPTYSLTVAASDGQGGL-----AT 487

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
             ++ + + D ND  P     +Y+ S++ED  V  N  + +  ATD D G    I Y++ G
Sbjct: 488  TSLTITVTDAND-APISVSASYSASIEEDAPVGTN--VIQTSATDVDSG--DTISYSLSG 542

Query: 194  GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
                  FSI   +G +   ++LDYE   SY L +   DG   + S T  + I++ + ND 
Sbjct: 543  ---SAHFSITG-TGLIKTAESLDYETTSSYSLTVSFFDG---TLSVTKAVSISVTNKND- 594

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
            AP   +S +  SVSE   +G ++  V A DAD      LTY++      G      +I  
Sbjct: 595  APVLPSSPYTASVSEGSLVGTAVYDVNATDAD---GDTLTYSL-----YGAGSSSFSISS 646

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             +G V T+  LD E    Y L +  TDG       T T              F+   Y  
Sbjct: 647  ATGVVTTAKALDYEAVTSYTLTIRVTDGNG---GITETSLTVTITNSNDSPQFLSTPYNT 703

Query: 374  ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
             + E+   GT V++++A D D  N L Y ++G N    FSI+S +  GL+T AQ LD + 
Sbjct: 704  AVDENLGTGTSVISVSAIDQDSGNTLTYSLSGTN-NAHFSISSAS--GLVTTAQALDHEA 760

Query: 434  ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
               Y LTVS +D      TA+V I +T+ N+ AP F NAPY+ASV E+   G+ V  VSA
Sbjct: 761  VSSYSLTVSVSDGTVTVTTALV-ITVTNRND-APAFSNAPYSASVAEN-NAGSAVYTVSA 817

Query: 494  TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            TD D G    +TY +S   S +        F I+  TG +T  + L+ E  + Y L++  
Sbjct: 818  TDEDSG--DTMTYFISGTGSGD--------FSIDSSTGVVTLARALNYEDTTYYSLSILV 867

Query: 554  RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
             DG     SD+T++ I+V D ND  PVF    Y A+I E   +GT+V +  ATD D   +
Sbjct: 868  LDG--KGESDSTNLNITVTDAND-APVFLSTPYAAHISEGVAIGTNVLKATATDQDT--S 922

Query: 614  GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
              + Y L         F +  ++G+I T   LDRESV+++ L  +++  GT   + T  V
Sbjct: 923  DTLTYAL--TGTNSAHFAVS-STGMISTAHVLDRESVSSYSL-TLSVSDGT--ANVTQGV 976

Query: 674  HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
             I + + ND  PVF     +  ++E    G     +      +G    + +S+  G  S 
Sbjct: 977  SITVVNAND-VPVFTGAPYSSTVAE----GDAAAAVYTASATDGDGDTLVFSL-SGTGST 1030

Query: 734  SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW-NDVRVEILVTDVNDNAP 792
            SFS+    G     +     L+YE+    Y L IRA           + I VT+ ND +P
Sbjct: 1031 SFSMNPSTG----VITLTAALNYET-SPAYSLTIRADDGNGGVATTTLNITVTNQND-SP 1084

Query: 793  VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851
            V            +  P+G    +V A D D  D L Y  LSG+N+    +  +TG +T 
Sbjct: 1085 VFSGTP-FSATLTENDPIGTTVLKVIAIDEDSADTLSYS-LSGSNSAHFAIGSSTGVITT 1142

Query: 852  SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            +  L+       ++ VSV+DG   +   + +++
Sbjct: 1143 AQLLDRETVNSYSLTVSVSDGTATVNQALSVTI 1175



 Score =  252 bits (616), Expect = 4e-66
 Identities = 255/906 (28%), Positives = 419/906 (46%), Gaps = 100/906 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D ND  P+F    + ASV E  ++  ++LTL ATD+D         + +++T   L
Sbjct: 1693 ITVIDSND-LPLFVDAPFSASVNENTTT-VSLLTLTATDED---------SSDMLTFSLL 1741

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P               ++F I   SG +   ++LD E  + Y + V+ +D    V+   
Sbjct: 1742 GPGS-------------ELFSIHPTSGVVSVTSALDAEVTSLYVLTVRVSDGKGGVN--- 1785

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              T+++ V +ID ND  P F    Y  SV E +  +   V+  I ATD D     ++ Y+
Sbjct: 1786 --TSSLSVTVIDVNDR-PAFVGAPYAASVSERLP-SGTGVVTLI-ATDQD---GDSLTYS 1837

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I G N    FSI   +G +   + LDYE V SY L     DG   S + TT + I++ + 
Sbjct: 1838 ISGTN-HGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDG---SVTVTTSVTISVTNT 1893

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  P   +S +  S++EN     S++ +   D+D      LTY++T    TG+ D   +
Sbjct: 1894 ND-PPTLSSSYYNVSINEN-DAALSVIDITGSDSD---GDTLTYSLTG---TGSGD--FS 1943

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ++  +G +  +  LD E+++ Y L +  TD     +    T               + G 
Sbjct: 1944 MNSATGLITLATALDYESRSAYSLTIRVTD----TKEGVVTASLFVTVVDQNDTPVLTGS 1999

Query: 371  -YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y   + E+   G  V  + A+D D  + ++Y ++G N+   FSI+S    G+IT A+ L
Sbjct: 2000 PYTARIEENLSSGGVVAHVVASDQDSADTMNYTLSGTNS-AHFSISS---AGVITSARVL 2055

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            D++    Y L V  TD    + T  V + + DAN+ APVF N+ +TA V E+   G  V 
Sbjct: 2056 DYESVSAYTLGVQVTDGTATASTT-VTVTVVDAND-APVFSNSTFTAQVSEN-DAGAAVC 2112

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
             VSATD+D G    +TY+L    S+        QF ++  TG +T + +LD E  S ++L
Sbjct: 2113 TVSATDADSGPADTLTYTLYGASSS--------QFSLHASTGVVTLSNVLDYEEASQHVL 2164

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            TV   DG   ++S  T + I V + ND  PVF+   YT +I E+   G+SV    ATD D
Sbjct: 2165 TVRVSDGRGGTVS--TSLTIKVQNQND-PPVFRGTPYTTSIDENLSAGSSVFVAIATDED 2221

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
             G      Y +   +  +  F +  A+G++ T K LD E + ++ L     D      S 
Sbjct: 2222 NG--DTCTYSISGVNSSD--FTMASATGILTTLKVLDFEQLNSYSLTVTVTDS---TSSV 2274

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
            +  + I + D+NDSP   ++   +  + ENS I  ++  + A D D   N  + YS+  G
Sbjct: 2275 SQPITITVSDVNDSPGFLDAP-YSISVQENS-INASLCTVSASDED---NDTLSYSLT-G 2328

Query: 730  DDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
              ++ F++ +  G     LVT+   L+YE        VI +      N   + + V DVN
Sbjct: 2329 SGASYFTIHSATG-----LVTLAKSLNYEGSSMFSLTVIVSDVQGASNTSTLTVNVLDVN 2383

Query: 789  DNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKLQYRILSGNNANLILLNETTG 847
            D    +     +  + ++    G    +  A D D  D L Y +   N+A+  + N  TG
Sbjct: 2384 DEPQFINSPYSV--SIRENLATGTRVLQASAADEDTGDTLTYSLSGSNHAHFSISN--TG 2439

Query: 848  SMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN----SITVRLNDM 903
             ++ +  ++  V    ++ V+V+DG   +   + +SV  + +  +      + T+  N  
Sbjct: 2440 VISTASGIDFEVVSSYSLSVAVSDGTVSVSEPVMISVENLNDSPVFTDAPYNATINENTS 2499

Query: 904  TAEQFL 909
            TA   L
Sbjct: 2500 TATSIL 2505



 Score =  235 bits (574), Expect = 5e-61
 Identities = 240/797 (30%), Positives = 364/797 (45%), Gaps = 68/797 (8%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I   +G +   A+LD E  + Y + V+  D         +++ T++V + D ND+ P 
Sbjct: 1552 FVIHASTGVVSLSAALDYEVKSSYVLGVEVRDGQGG-----TASTTLNVTVSDANDS-PV 1605

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            F    Y+  V ED++V     + +  A D D  A+  + Y + G N+   F++ + +G +
Sbjct: 1606 FVGTPYSAMVAEDVNV--GHTVFRSSAVDED--ASDTLTYTLSGTNST-HFTMATSTGII 1660

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            +  + LDYE + SY L I   DG   + S T  + I + D ND  P F  + F  SV+EN
Sbjct: 1661 TTAEGLDYESLTSYTLTITVSDG---TASVTQPITITVIDSND-LPLFVDAPFSASVNEN 1716

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
                 S++ + A D D   +  LT+++      G      +I P SG V  +  LD E  
Sbjct: 1717 TTT-VSLLTLTATDEDS--SDMLTFSL-----LGPGSELFSIHPTSGVVSVTSALDAEVT 1768

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
            + Y L V  +DG         +              F+   Y   ++E  P GT VVTL 
Sbjct: 1769 SLYVLTVRVSDG---KGGVNTSSLSVTVIDVNDRPAFVGAPYAASVSERLPSGTGVVTLI 1825

Query: 390  ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
            ATD D D+ L Y I+G N  G FSI+     GLI  AQ LD++    Y LT S TD G  
Sbjct: 1826 ATDQDGDS-LTYSISGTN-HGHFSISPST--GLIQTAQILDYESVNSYTLTASVTD-GSV 1880

Query: 450  SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
            + T  V I++T+ N+  P   ++ Y  S+ E+     +V+ ++ +DSD      +TYSL+
Sbjct: 1881 TVTTSVTISVTNTND-PPTLSSSYYNVSINEN-DAALSVIDITGSDSD---GDTLTYSLT 1935

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
               S +        F +N  TG IT    LD E+ S Y LT+   D     +  T  + +
Sbjct: 1936 GTGSGD--------FSMNSATGLITLATALDYESRSAYSLTIRVTDTKEGVV--TASLFV 1985

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            +VVD ND  PV     YTA I E+   G  V+ V A+D D      ++Y L         
Sbjct: 1986 TVVDQNDT-PVLTGSPYTARIEENLSSGGVVAHVVASDQDSA--DTMNYTL--SGTNSAH 2040

Query: 630  FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
            F I  A GVI + + LD ESV+ + L  V +  GT   S+TV V   + D ND+ PVF +
Sbjct: 2041 FSISSA-GVITSARVLDYESVSAYTL-GVQVTDGTATASTTVTV--TVVDANDA-PVFSN 2095

Query: 690  DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
               T  +SEN   G  +  + A D D GP   + Y++ G   S+ FSL    G     +V
Sbjct: 2096 STFTAQVSEND-AGAAVCTVSATDADSGPADTLTYTLYGA-SSSQFSLHASTG-----VV 2148

Query: 750  TMVD-LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
            T+ + LDYE    ++ L +R  S      V   + +   N N P +        +  +  
Sbjct: 2149 TLSNVLDYEE-ASQHVLTVR-VSDGRGGTVSTSLTIKVQNQNDPPVFRGTPYTTSIDENL 2206

Query: 809  PVGPFGRVP-AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
              G    V  A D D  D   Y I SG N++   +   TG +T    L+       ++ V
Sbjct: 2207 SAGSSVFVAIATDEDNGDTCTYSI-SGVNSSDFTMASATGILTTLKVLDFEQLNSYSLTV 2265

Query: 868  SVTDGVNEIKAMMQLSV 884
            +VTD  + +   + ++V
Sbjct: 2266 TVTDSTSSVSQPITITV 2282



 Score =  230 bits (563), Expect = 1e-59
 Identities = 209/675 (30%), Positives = 320/675 (47%), Gaps = 81/675 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + + ND SP F    Y  +V E   +GT+V+++ A DQD G       T+    + T 
Sbjct: 685  VTITNSND-SPQFLSTPYNTAVDENLGTGTSVISVSAIDQDSGN------TLTYSLSGTN 737

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                  F I   SG + T  +LD E V+ Y++ V  +D    V+  L
Sbjct: 738  NAH----------------FSISSASGLVTTAQALDHEAVSSYSLTVSVSDGTVTVTTAL 781

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              T T       + ++ P FS   Y+ SV E+ +      +  + ATD D G    + Y 
Sbjct: 782  VITVT-------NRNDAPAFSNAPYSASVAENNA---GSAVYTVSATDEDSG--DTMTY- 828

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
             I G     FSIDS +G V+L + L+YE    Y L I   DG     S++T L I + D 
Sbjct: 829  FISGTGSGDFSIDSSTGVVTLARALNYEDTTYYSLSILVLDG--KGESDSTNLNITVTDA 886

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND AP F ++ +   +SE V IG ++++  A D D   +  LTY +T    T +    ++
Sbjct: 887  ND-APVFLSTPYAAHISEGVAIGTNVLKATATDQD--TSDTLTYALTG---TNSAHFAVS 940

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
                +G + T+  LDRE+ + Y L ++ +DG     +A  T                 G 
Sbjct: 941  ---STGMISTAHVLDRESVSSYSLTLSVSDG-----TANVTQGVSITVVNANDVPVFTGA 992

Query: 371  -YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y   +AE +     V T +ATD D D  L + ++G    G  S +     G+IT+   L
Sbjct: 993  PYSSTVAEGDAAAA-VYTASATDGDGDT-LVFSLSG---TGSTSFSMNPSTGVITLTAAL 1047

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            +++    Y LT+ A D  G   T  + I +T+ N+ +PVF   P++A++ E+ PIGTTVL
Sbjct: 1048 NYETSPAYSLTIRADDGNGGVATTTLNITVTNQND-SPVFSGTPFSATLTENDPIGTTVL 1106

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
             V A D D      ++YSLS   SN A       F I   TG ITT +LLDRET++ Y L
Sbjct: 1107 KVIAIDEDSADT--LSYSLSG--SNSA------HFAIGSSTGVITTAQLLDRETVNSYSL 1156

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            TV+  DG   + +    + +++ D ND  P+F    Y A + E+A  G SV  V ATDAD
Sbjct: 1157 TVSVSDG---TATVNQALSVTINDAND-APLFTNAPYNATVNENAGSG-SVYTVSATDAD 1211

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
              +   I Y +     ++  F I  +SG++    A+D E+ ++  L   A D  T    +
Sbjct: 1212 SDV---IAYSIYGHGSDK--FSIHSSSGLVTLASAVDFETKSSFVLTVQAAD--TNGAIA 1264

Query: 670  TVIVHIKIEDINDSP 684
            T  +++ + + NDSP
Sbjct: 1265 TTSLYVDVVNQNDSP 1279



 Score =  229 bits (561), Expect = 2e-59
 Identities = 175/572 (30%), Positives = 267/572 (46%), Gaps = 40/572 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND+ PVF    Y  S+ E  S+GT V+ + ATD D G NAE+ Y+I  V  D 
Sbjct: 5080 RIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSI--VGGDA 5137

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N                  F ++  +G + T A+LDRE +A YT+LV+A+D+  P    
Sbjct: 5138 KNQ-----------------FSVNS-TGMIRTIATLDREDIASYTLLVQASDRGVPPQ-- 5177

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + T  + V I+D NDN   FS+  ++  V ED  V        I A+DAD G N+ + Y
Sbjct: 5178 -TETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFR--FMNISASDADSGDNARLTY 5234

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I  GNT    +I+S +G +  V   D E+  +Y L IRA D G+P   +T    I I D
Sbjct: 5235 SIQSGNTDNVVAIESATGALYSVGAFDRERTATYTLAIRAIDAGNPPLFSTITAHIVIID 5294

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P F  + +   V+EN P G SI  V+A D D G +A+L YT+     + +     
Sbjct: 5295 RNDNTPTFLDADYNFVVTENQPGGLSIGHVRAIDIDNGTHAQLVYTIEPSPNSNH----F 5350

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFM 367
            T++P +G ++T+  LDRE    Y+L V  TD    P     T T              F 
Sbjct: 5351 TMNPITGGLFTAMALDRENVPYYRLTVRVTDSAAYPSQLFNTTTVHITVLDLNDNPPAFD 5410

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITV 425
               +   +AE+   G  V  +TA+D D D   RL Y +T   +   +        G + +
Sbjct: 5411 KAVFNASIAENSESGASVTRVTASDRDRDANARLTYSLTYNASSPEY-FRLDEATGEVFL 5469

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
               +D++  +   +TV+A D G    S +  +++++ D N+ APVF    Y   +  D  
Sbjct: 5470 KSGVDYENVQIIEVTVTAKDDGFPSLSGSTTLRVHVIDLNDNAPVFSATFYETEIRSDHN 5529

Query: 484  IGT-TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            +G   ++ ++A D D G N+ +TY L        +  +  + V+    GA        R 
Sbjct: 5530 LGPPAIITLTAIDRDSGPNSAVTYELEQTQEKFKLDTNSGEIVLKASPGAGQIYSFRARA 5589

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
              SG   +       V    DT D E ++VD+
Sbjct: 5590 KDSG---SPQLSSSYVNVRVDTIDAEQTMVDI 5618



 Score =  208 bits (508), Expect = 5e-53
 Identities = 193/643 (30%), Positives = 309/643 (48%), Gaps = 62/643 (9%)

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           +DV    P F ++ +  +V+ENV I  ++    + A D+D      +T ++         
Sbjct: 199 QDVQGAPPVFGSAAYSGTVNENVAIDTTVSGFTISATDSD---GQAITISIISSPG---- 251

Query: 306 DLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             P  +      + T+G+ +D ET + Y L + A  GG+   +AT T             
Sbjct: 252 --PFKLKSDGTKILTNGESIDFETTSSYTLTIQALAGGETD-NATVT---ITIGNINEAP 305

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            F    Y   + E+   GT ++T+TA+D D  + + Y ++G  +    ++T+    G+I 
Sbjct: 306 SFALASYSGRIHENSVNGTDIITVTASDVDSGDTITYSLSGSGSSSFSALTT----GVIE 361

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           V+  LDF+    Y LT++ATD+GG +DTA + I++ + N  +PVF +A Y ASV E+   
Sbjct: 362 VSGSLDFEATPTYTLTLTATDTGGLTDTATLTISVDNVNE-SPVFTSASYAASVAEN-DA 419

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
             +V+ V+ATD DVG    +TYSL+   S+         F ++P +G +   + LD ET 
Sbjct: 420 AASVVTVAATDPDVG--NSVTYSLTGSGSS--------HFTVHPTSGVVILTQALDYETK 469

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
             Y LTV A D G   L+ TT + I+V D ND  P+     Y+A+I EDA VGT+V Q  
Sbjct: 470 PTYSLTVAASD-GQGGLA-TTSLTITVTDAND-APISVSASYSASIEEDAPVGTNVIQTS 526

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           ATD D G    I Y L         F I   +G+I+T ++LD E+ +++ L     DG  
Sbjct: 527 ATDVDSG--DTISYSLS----GSAHFSI-TGTGLIKTAESLDYETTSSYSLTVSFFDG-- 577

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
              S T  V I + + ND+ PV  S   T  +SE S +GT + ++ A D D      + Y
Sbjct: 578 -TLSVTKAVSISVTNKNDA-PVLPSSPYTASVSEGSLVGTAVYDVNATDAD---GDTLTY 632

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW-NDVRVEIL 783
           S+ G   S+SFS+ +  G     + T   LDYE+    Y L IR         +  + + 
Sbjct: 633 SLYGA-GSSSFSISSATG----VVTTAKALDYEAV-TSYTLTIRVTDGNGGITETSLTVT 686

Query: 784 VTDVNDNAPVMKDFQIIFNNYKD-CFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLIL 841
           +T+ ND+   +      +N   D     G     V A D D  + L Y +   NNA+   
Sbjct: 687 ITNSNDSPQFL---STPYNTAVDENLGTGTSVISVSAIDQDSGNTLTYSLSGTNNAH-FS 742

Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
           ++  +G +T +  L+       ++ VSV+DG   +   + ++V
Sbjct: 743 ISSASGLVTTAQALDHEAVSSYSLTVSVSDGTVTVTTALVITV 785



 Score =  198 bits (483), Expect = 5e-50
 Identities = 176/642 (27%), Positives = 271/642 (42%), Gaps = 63/642 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + +   N++ P F    Y  + +E  + G T+ T+ ATD D G +  + + I        
Sbjct: 3848 VQITGANEYEPAFSQPTYSVTHQEDTAIGVTIATVAATDADHGSDGAISFAI-------- 3899

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +D F ID  SG +  +  LDRE    Y + V A D  SP     
Sbjct: 3900 -----------IAGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSP---NK 3945

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS A++ V ++D NDN P  S   + V V E+ SV     + +++  D D GANS + Y 
Sbjct: 3946 SSNASVDVTVVDVNDNAPNCSVTAHVVEVAENASV--GSTVLELRCEDVDEGANSQLTYN 4003

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-----GSPSRSNTTQLLI 245
            I    T      D    D   V   D E   +    + +  G        +R +T    +
Sbjct: 4004 I---TTDKDDDGDGDDNDGDAVDC-DSEGNTNSDFTLNSSSGVLTVASQLNRESTVYYDL 4059

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             +   +   P   T   Q S+SE+V +G ++    A D D+G +  +TY +     +GN 
Sbjct: 4060 TVTITDSGTPPLTTLHLQHSLSEDVSLGTTVFIAHAQDYDDGEHGHVTYAIL----SGNT 4115

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXX 363
                 +D  SG +     LD E  + Y+L++ A+DG +    +S+  T            
Sbjct: 4116 ADTFLLDKYSGSLQLLRSLDYEVASSYKLIIEASDGAEVSVRKSSRITVNIAVIDLNDNK 4175

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRL-HYEITGGNTRGRFSITSQNGRG 421
                     V L E    GT + +   +D+D  DN L  Y+I  GN  G+F++TS    G
Sbjct: 4176 PECSETTKHVSLLESVVVGTVIFSTNCSDSDSSDNALLTYQILTGNAEGKFNVTSG---G 4232

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAP--YTAS 477
             +T+A  L  +    Y L V+  D+G  S    V   + +   N + P F      Y+ +
Sbjct: 4233 EVTLASGLSVEMTSWYHLVVAVRDAGSPSRAVNVSLTVEVLPVNEFVPTFAAGGDLYSLN 4292

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTN 536
            VFE+  +GT V      D+D G++  + +SL        V+ +DQ  F + P +G +   
Sbjct: 4293 VFENVTLGTIVFQAQVQDNDTGLHGTLRFSL--------VSGNDQGCFYLEPSSGMLVLV 4344

Query: 537  KLLDRETMSGYLLTVTARDGGV--PSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
              LDRET+  Y + V   D     P + S    V I+V+DVNDN+P     LY+A+I E 
Sbjct: 4345 SPLDRETVDHYSVMVKVEDSSQSDPDVRSSNVTVAITVLDVNDNDPECVPALYSADISEG 4404

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
               G  V  + + D   G  G     L   D  EG     PA
Sbjct: 4405 K--GEFVPALYSADISEG-KGEFVPALYSADISEGKGEFVPA 4443



 Score =  190 bits (463), Expect = 1e-47
 Identities = 141/464 (30%), Positives = 216/464 (46%), Gaps = 41/464 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +H  + +LD ND++ VF    + A V E A  G   + + A+D D G NA + Y+I+   
Sbjct: 5181 VHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGN 5240

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             D                   +V  I+  +GAL +  + DRE+ A YT+ ++A D  +P 
Sbjct: 5241 TD-------------------NVVAIESATGALYSVGAFDRERTATYTLAIRAIDAGNP- 5280

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               L ST T H+ IID NDN P F +  Y   V E  +      I  ++A D D G ++ 
Sbjct: 5281 --PLFSTITAHIVIIDRNDNTPTFLDADYNFVVTE--NQPGGLSIGHVRAIDIDNGTHAQ 5336

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSR-SNTTQLL 244
            + Y I        F+++ ++G +     LD E V  YRL +R  D  + PS+  NTT + 
Sbjct: 5337 LVYTIEPSPNSNHFTMNPITGGLFTAMALDRENVPYYRLTVRVTDSAAYPSQLFNTTTVH 5396

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            I + D+NDN P F  ++F  S++EN   G S+ RV A D D   NA LTY++T   Y  +
Sbjct: 5397 ITVLDLNDNPPAFDKAVFNASIAENSESGASVTRVTASDRDRDANARLTYSLT---YNAS 5453

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                  +D  +G V+    +D E     ++ VTA D G P  S + T             
Sbjct: 5454 SPEYFRLDEATGEVFLKSGVDYENVQIIEVTVTAKDDGFPSLSGSTTLRVHVIDLNDNAP 5513

Query: 365  XFMPGQYEVELAEDEPPGTP-VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
             F    YE E+  D   G P ++TLTA D D   ++ + YE+    T+ +F + + +G  
Sbjct: 5514 VFSATFYETEIRSDHNLGPPAIITLTAIDRDSGPNSAVTYELE--QTQEKFKLDTNSGE- 5570

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDA 462
            ++  A P      + Y     A DSG     S    V+++  DA
Sbjct: 5571 IVLKASP---GAGQIYSFRARAKDSGSPQLSSSYVNVRVDTIDA 5611



 Score =  185 bits (450), Expect = 5e-46
 Identities = 254/939 (27%), Positives = 384/939 (40%), Gaps = 116/939 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD------------------I 52
            I V + ND SPVF    + A++ E    GTTVL + A D+D                  I
Sbjct: 1075 ITVTNQND-SPVFSGTPFSATLTENDPIGTTVLKVIAIDEDSADTLSYSLSGSNSAHFAI 1133

Query: 53   GKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI---DGRSGALLTRASLD--- 106
            G +  V  T +L+  +T+N              V     +   D     L T A  +   
Sbjct: 1134 GSSTGVITTAQLLDRETVNSYSLTVSVSDGTATVNQALSVTINDANDAPLFTNAPYNATV 1193

Query: 107  REKVARYTVL-VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165
             E     +V  V ATD  S V        +I+ +  D    +      T   +VD +   
Sbjct: 1194 NENAGSGSVYTVSATDADSDVI-----AYSIYGHGSDKFSIHSSSGLVTLASAVDFE--- 1245

Query: 166  TDNPVIAKIKATDADVG-ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
            T +  +  ++A D +   A +++   ++  N    F     S  + +   LDYE   SY 
Sbjct: 1246 TKSSFVLTVQAADTNGAIATTSLYVDVVNQNDSPAFMGTPYSTSI-IESALDYESASSYS 1304

Query: 225  LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
            L +   DG   + S TT L I+I DVND AP F ++ +  SV+EN   G ++  V   D 
Sbjct: 1305 LTVTVNDG---TVSMTTPLTISIADVND-APVFTSAPYTTSVNEN-EAGAAVYTVSGTDQ 1359

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            D G +   T   +   Y        T+ P +G V  S  LD ET   Y L + A+D    
Sbjct: 1360 DSGDSVSFTMYGSGSSY-------FTLHPTTGVVTLSRALDYETTPLYTLTIIASDTNQG 1412

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404
              S T T               +   Y  ++ E+   G  V+ LTATD D ++ L Y +T
Sbjct: 1413 LASTTLTVTVTDQNDEPK---LVGTPYYAQVDENLNSGATVMKLTATDQDSNSTLSYTLT 1469

Query: 405  GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464
            G N  G FSI++    GLIT  Q LD++    Y L VS TD G  + T  + I + + N+
Sbjct: 1470 GSNN-GHFSISAT---GLITTTQELDYETINTYSLNVSVTD-GTTTVTEGLTITVRNKND 1524

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
                          F  AP   TV   +A    VG                        F
Sbjct: 1525 DPS-----------FTSAPYSATVTENNAVPPWVG---------------------SADF 1552

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            VI+  TG ++ +  LD E  S Y+L V  RDG   + S T +V +S  D ND+ PVF   
Sbjct: 1553 VIHASTGVVSLSAALDYEVKSSYVLGVEVRDGQGGTASTTLNVTVS--DANDS-PVFVGT 1609

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
             Y+A + ED  VG +V +  A D D   +  + Y L   +     F +  ++G+I T + 
Sbjct: 1610 PYSAMVAEDVNVGHTVFRSSAVDEDA--SDTLTYTLSGTNSTH--FTMATSTGIITTAEG 1665

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LD ES+ ++ L     DG     S T  + I + D ND  P+F     +  ++EN+   T
Sbjct: 1666 LDYESLTSYTLTITVSDG---TASVTQPITITVIDSNDL-PLFVDAPFSASVNENT---T 1718

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            T+  +     DE  + ++ +S+  G  S  FS+    G     + + +D +  S    Y 
Sbjct: 1719 TVSLLTLTATDEDSSDMLTFSLL-GPGSELFSIHPTSG--VVSVTSALDAEVTS---LYV 1772

Query: 765  LVIRAASPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
            L +R +      N   + + V DVND  P          +  +  P G  G V     D 
Sbjct: 1773 LTVRVSDGKGGVNTSSLSVTVIDVNDR-PAFVGAPYA-ASVSERLPSGT-GVVTLIATDQ 1829

Query: 824  T-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL 882
              D L Y I SG N     ++ +TG +  +  L+       T+  SVTDG   +   + +
Sbjct: 1830 DGDSLTYSI-SGTNHGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDGSVTVTTSVTI 1888

Query: 883  SVRLITEEMLLNS--ITVRLNDMTAEQFLSPLLGFFIDG 919
            SV    +   L+S    V +N+  A   +  + G   DG
Sbjct: 1889 SVTNTNDPPTLSSSYYNVSINENDAALSVIDITGSDSDG 1927



 Score =  112 bits (269), Expect = 4e-24
 Identities = 127/435 (29%), Positives = 199/435 (45%), Gaps = 42/435 (9%)

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTV--LVVSATDSDVGINAQITYSLSSE 511
           +V     D     PVF +A Y+ +V E+  I TTV    +SATDSD      IT S+ S 
Sbjct: 193 LVSFVCQDVQGAPPVFGSAAYSGTVNENVAIDTTVSGFTISATDSD---GQAITISIISS 249

Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
                +         +  T  +T  + +D ET S Y LT+ A  GG    +D   V I++
Sbjct: 250 PGPFKLK--------SDGTKILTNGESIDFETTSSYTLTIQALAGGE---TDNATVTITI 298

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            ++N+  P F    Y+  I E+++ GT +  V A+D D G    I Y L        S +
Sbjct: 299 GNINE-APSFALASYSGRIHENSVNGTDIITVTASDVDSG--DTITYSLSGSGSSSFSAL 355

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
               +GVI  + +LD E+  T+ L   A D G    ++T+   I ++++N+S PVF S  
Sbjct: 356 ---TTGVIEVSGSLDFEATPTYTLTLTATDTGGLTDTATLT--ISVDNVNES-PVFTSAS 409

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
               ++EN    + +  + A DPD G N+V  YS+ G   S+ F++    G     ++T 
Sbjct: 410 YAASVAENDAAASVV-TVAATDPDVG-NSVT-YSLTGSGSSH-FTVHPTSG---VVILTQ 462

Query: 752 VDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
             LDYE+ +  Y L + A+          + I VTD ND AP+        +  +D  PV
Sbjct: 463 A-LDYET-KPTYSLTVAASDGQGGLATTSLTITVTDAND-APISVSASYSASIEEDA-PV 518

Query: 811 GP-FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
           G    +  A D D  D + Y  LSG +A+  +    TG +  +  L+       ++ VS 
Sbjct: 519 GTNVIQTSATDVDSGDTISYS-LSG-SAHFSITG--TGLIKTAESLDYETTSSYSLTVSF 574

Query: 870 TDGVNEIKAMMQLSV 884
            DG   +   + +SV
Sbjct: 575 FDGTLSVTKAVSISV 589



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 52/226 (23%), Positives = 96/226 (42%), Gaps = 13/226 (5%)

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
           +V    +D+  +PPVF S   +  ++EN  I TT+        D    A+   +I     
Sbjct: 193 LVSFVCQDVQGAPPVFGSAAYSGTVNENVAIDTTVSGFTISATDSDGQAI---TISIISS 249

Query: 732 SNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790
              F L+    SD  +++T  + +D+E+    Y L I+A +    ++  V I + ++N+ 
Sbjct: 250 PGPFKLK----SDGTKILTNGESIDFET-TSSYTLTIQALAGGETDNATVTITIGNINE- 303

Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850
           AP           +++         V A D D  D + Y +    +++   L  TTG + 
Sbjct: 304 APSFALASYSGRIHENSVNGTDIITVTASDVDSGDTITYSLSGSGSSSFSAL--TTGVIE 361

Query: 851 LSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNS 895
           +S  L+       T+ ++ TD G     A + +SV  + E  +  S
Sbjct: 362 VSGSLDFEATPTYTLTLTATDTGGLTDTATLTISVDNVNESPVFTS 407


>SB_48962| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 2225

 Score =  345 bits (848), Expect = 3e-94
 Identities = 246/789 (31%), Positives = 384/789 (48%), Gaps = 53/789 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           IN+LD ND+SP    ++Y A V E +  GT V T+KATD D G N EVEY I      T 
Sbjct: 152 INILDVNDNSPQPARREYRAHVAENSDVGTLVTTVKATDPDAGVNGEVEYCI----VQTA 207

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             E A             +F+I+  SG +LT   LD E +  + + +KA+D+  P  + L
Sbjct: 208 KAESAS------------LFKIESHSGRILTVKPLDYETMQEHVLTIKASDRGIPKRETL 255

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S     V++ D ND+ P+F    +   VD  +S      I ++ ATD D G NS ++Y+
Sbjct: 256 FSVV---VSVDDVNDHKPEFLSPLFESEVD--VSAKAGTAILRVIATDKDDGTNSKLKYS 310

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I+ GNT    S+D  SG V +   L    V  Y L +++ DGG P       +  N ++ 
Sbjct: 311 IVSGNTNKSLSVDQNSGVVKVAGRLS-TLVHQYALKVQSTDGGEPPLKTQVDVKYNQKEC 369

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           ND AP F  SL+  ++SE+ P+  ++V V+A D D G+N E+ Y + +    G       
Sbjct: 370 NDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSRVGAF---FK 426

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           ID +SG V+ +  LD E++  +++++ A D G P  +                  F    
Sbjct: 427 IDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGETRVRVVLMDANDNAPRFDKSM 486

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           Y   +     PG  V  + ATD DE +  +L Y ITGG  R  F I SQ+  G+IT+++ 
Sbjct: 487 YAASILGSASPGQFVTRILATDPDEGDAKKLRYSITGGQGRQHFQIDSQS--GVITLSRV 544

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           +  KQ + Y L V  +DS   S T+ V++ I D N+++P+F    Y  S  E+ P GT V
Sbjct: 545 VGIKQGKVYGLDVEVSDSVHVS-TSKVRVIIGDTNDHSPIFSEDVYKVSFNENYPEGTFV 603

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            +VSATD D G  A +TYS+ S    +A+    ++F I+  +G + +  + DRE  S  +
Sbjct: 604 TMVSATDLDSGNYAHLTYSIDSV---DAM----RKFRIDADSGMLYSRLMFDRENSSQAI 656

Query: 549 LTVTAR--DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           ++V  R  DGG         VE+ ++D NDN+P+F+ + Y   I     +GT V    A+
Sbjct: 657 MSVPIRATDGG--GRFGFCVVEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSAS 714

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D   N  + Y +    +    F I+ A+GVI+ ++      V +++   +  DGG P 
Sbjct: 715 DPDASSNAALTYVI-VGHQTPPVFTINAATGVIQVSR---EPEVKSYNFFVLVKDGGNPL 770

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             S   V I + + +     F        + EN+ +G  +  +    P   P  V +  I
Sbjct: 771 LRSIASVKITVLERDARILHFGKSKYDVTVGENAEMGQIVTGLNLVVPGGNPVDVDYRII 830

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVR--VEIL 783
           KG +D+N    + + G D    V ++  LDYE  R +Y +++ A    +    R  V + 
Sbjct: 831 KGNNDNN----DRKFGVDSTGRVRVIGRLDYEI-RNRYVMIVEANVSAINQIARTVVVVQ 885

Query: 784 VTDVNDNAP 792
           V D+ND  P
Sbjct: 886 VLDINDVTP 894



 Score =  291 bits (713), Expect = 7e-78
 Identities = 242/818 (29%), Positives = 379/818 (46%), Gaps = 56/818 (6%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            N  +CND +P F    Y A++ E     T V+T+KA D D G N E+ Y I+ V+     
Sbjct: 365  NQKECNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSR---- 420

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
                          V   F+ID +SG +    SLD E    + +++ A D+  P    L+
Sbjct: 421  --------------VGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKP---SLT 463

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
                + V ++D NDN P+F +  Y  S+    S +    + +I ATD D G    +RY+I
Sbjct: 464  GETRVRVVLMDANDNAPRFDKSMYAASILG--SASPGQFVTRILATDPDEGDAKKLRYSI 521

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
             GG  +  F IDS SG ++L + +  +Q + Y L +   D    S   T+++ + I D N
Sbjct: 522  TGGQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDSVHVS---TSKVRVIIGDTN 578

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            D++P F   +++ S +EN P G  +  V A D D G  A LTY++   D          I
Sbjct: 579  DHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRK----FRI 634

Query: 312  DPRSGWVYTSGQLDRE--TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            D  SG +Y+    DRE  +QA   + + ATDGG   R                   F   
Sbjct: 635  DADSGMLYSRLMFDRENSSQAIMSVPIRATDGGG--RFGFCVVEVHLIDENDNQPIFELK 692

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y+  ++     GTPV+  +A+D D  +   L Y I G  T   F+I +    G+I V++
Sbjct: 693  NYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVIVGHQTPPVFTINA--ATGVIQVSR 750

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
              + K    +VL     +   RS  A V+I + + +     F  + Y  +V E+A +G  
Sbjct: 751  EPEVKSYNFFVLVKDGGNPLLRS-IASVKITVLERDARILHFGKSKYDVTVGENAEMGQI 809

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V  ++      G    + Y +    +N+   ++D++F ++  TG +     LD E  + Y
Sbjct: 810  VTGLNLVVPG-GNPVDVDYRIIKG-NND---NNDRKFGVD-STGRVRVIGRLDYEIRNRY 863

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            ++ V A    +  ++ T  V + V+D+ND  P F    Y A+I E+  +G+ V +V A D
Sbjct: 864  VMIVEANVSAINQIARTV-VVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAED 922

Query: 608  ADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
             D G NG + Y L  KD+  +  F ID  +G I T  ALDRE   + + +  A D GT  
Sbjct: 923  LDSGSNGMVTYALVSKDKLVKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTR 982

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             +S   V   + D+ND+PP F     T  + E++ IG ++  I A   DE  N  ++Y I
Sbjct: 983  LTSLTTVRAIVLDVNDTPPKFSQSEFTASVKEDALIGQSVTTITA--TDEDLNTELYYFI 1040

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786
              GD    F +E + G     +     LD ES    Y+L I A+     +  +++I + D
Sbjct: 1041 LSGDPQARFGIERKTG----VIFVHGSLDRESV-GSYDLNISASDGLFTSFAQMKIDIED 1095

Query: 787  VNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823
             NDN P+     I   + K+  P+G     V A DADV
Sbjct: 1096 ANDNPPICTQ-SIYVEHIKENTPLGSTVLTVGATDADV 1132



 Score =  289 bits (710), Expect = 2e-77
 Identities = 225/727 (30%), Positives = 346/727 (47%), Gaps = 59/727 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ ++D ND++P F+   Y AS+   AS G  V  + ATD D G   ++ Y+I       
Sbjct: 469  RVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSI------- 521

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             +  F+ID +SG +     +  ++   Y + V+ +D        
Sbjct: 522  ------------TGGQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDSVHV---- 565

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              ST+ + V I D ND+ P FSE  Y VS +E+    +   +  + ATD D G  + + Y
Sbjct: 566  --STSKVRVIIGDTNDHSPIFSEDVYKVSFNENYP--EGTFVTMVSATDLDSGNYAHLTY 621

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV----IRAQDGGSPSRSNTTQLLI 245
            +I   +   +F ID+ SG   L   L +++  S + +    IRA DGG   R     + +
Sbjct: 622  SIDSVDAMRKFRIDADSG--MLYSRLMFDRENSSQAIMSVPIRATDGGG--RFGFCVVEV 677

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            ++ D NDN P F    +  ++S +V +G  ++   A D D   NA LTY +      G+ 
Sbjct: 678  HLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVIV-----GHQ 732

Query: 306  DLPI-TIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
              P+ TI+  +G +    Q+ RE + K Y   V   DGG+P   + A+            
Sbjct: 733  TPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDARI 788

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLT-ATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
              F   +Y+V + E+   G  V  L           + Y I  GN          +  G 
Sbjct: 789  LHFGKSKYDVTVGENAEMGQIVTGLNLVVPGGNPVDVDYRIIKGNNDNNDRKFGVDSTGR 848

Query: 423  ITVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            + V   LD++   RYV+ V A  S   +    +V + + D N+  P F + PY AS+ E+
Sbjct: 849  VRVIGRLDYEIRNRYVMIVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPEN 908

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              IG+ VL V A D D G N  +TY+L   +S + +    ++F I+  TG ITT   LDR
Sbjct: 909  IDIGSKVLRVFAEDLDSGSNGMVTYAL---VSKDKLVK--EKFDIDQHTGWITTRGALDR 963

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E    +   V A D G   L+  T V   V+DVND  P F Q  +TA++ EDAL+G SV+
Sbjct: 964  EKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSEFTASVKEDALIGQSVT 1023

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             + ATD D  LN  ++Y +   D  +  F I+  +GVI  + +LDRESV ++DL   A D
Sbjct: 1024 TITATDED--LNTELYYFILSGD-PQARFGIERKTGVIFVHGSLDRESVGSYDLNISASD 1080

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G     +S   + I IED ND+PP+        +I EN+P+G+T+  + A D D G NA 
Sbjct: 1081 G---LFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAE 1137

Query: 722  VHYSIKG 728
            + YS+ G
Sbjct: 1138 LTYSVFG 1144



 Score =  285 bits (700), Expect = 3e-76
 Identities = 241/850 (28%), Positives = 385/850 (45%), Gaps = 52/850 (6%)

Query: 90  FRIDGRSGALLTRASL-DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND--- 145
           F ID RSG + T  SL D E    Y + + A D   P   +LS++  + +++I  N    
Sbjct: 7   FIIDSRSGEIFTNVSLVDGES---YDLTIVAEDNGLP---KLSTSTNVLIDVIQGNKPSK 60

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
           N P F  K Y+  + ED  +  N  +  I A D D      I Y I  GN   +F+ID  
Sbjct: 61  NAPVFWNKQYSADIQEDKRI--NSFVLIIGAEDPDF---DQITYNIASGNHGNKFTIDRY 115

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            G +++  +LD E+   Y L + A DG + +   +  + INI DVNDN+P+     ++  
Sbjct: 116 GGFITVAHSLDREEKSFYSLRVEATDGYNTA---SVPVTINILDVNDNSPQPARREYRAH 172

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           V+EN  +G  +  V+A D D GVN E+ Y +       +  L   I+  SG + T   LD
Sbjct: 173 VAENSDVGTLVTTVKATDPDAGVNGEVEYCIVQTAKAESASL-FKIESHSGRILTVKPLD 231

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            ET  ++ L + A+D G P R    +              F+   +E E+      GT +
Sbjct: 232 YETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVSAKAGTAI 291

Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
           + + ATD D+  +++L Y I  GNT    S+  QN  G++ VA  L      +Y L V +
Sbjct: 292 LRVIATDKDDGTNSKLKYSIVSGNTNKSLSV-DQNS-GVVKVAGRLS-TLVHQYALKVQS 348

Query: 444 TDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
           TD G       V +  N  + N+ AP F  + Y A++ E  P+ T V+ V A D D GIN
Sbjct: 349 TDGGEPPLKTQVDVKYNQKECNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGIN 408

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
            +I Y + +      V+     F I+ ++G +   K LD E+   + + + A D G PSL
Sbjct: 409 KEINYFIQN------VSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSL 462

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           +  T V + ++D NDN P F + +Y A+I+  A  G  V+++ ATD D G   ++ Y + 
Sbjct: 463 TGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSIT 522

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
                +  F ID  SGVI  ++ +  +    + L     D       ST  V + I D N
Sbjct: 523 GGQGRQ-HFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDS---VHVSTSKVRVIIGDTN 578

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D  P+F  D      +EN P GT +  + A D D G  A + YSI   D    F ++   
Sbjct: 579 DHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADS 638

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV--MKDFQ 798
           G   + L  M D +  S +    + IRA      +    VE+ + D NDN P+  +K++ 
Sbjct: 639 GMLYSRL--MFDRE-NSSQAIMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYD 695

Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLN 856
              +  +      P     A D D +    L Y I+      +  +N  TG + +S +  
Sbjct: 696 TTIS--RSVTMGTPVLMTSASDPDASSNAALTYVIVGHQTPPVFTINAATGVIQVSREPE 753

Query: 857 TNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGF 915
               K     V V DG N  ++++  + + ++  +  +        D+T  +  +  +G 
Sbjct: 754 V---KSYNFFVLVKDGGNPLLRSIASVKITVLERDARILHFGKSKYDVTVGE--NAEMGQ 808

Query: 916 FIDGLAAIIP 925
            + GL  ++P
Sbjct: 809 IVTGLNLVVP 818



 Score =  269 bits (659), Expect = 2e-71
 Identities = 239/885 (27%), Positives = 384/885 (43%), Gaps = 62/885 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V D NDH P F    +E+ V   A +GT +L + ATD+D G N++++Y+I  V+ +T 
Sbjct: 260  VSVDDVNDHKPEFLSPLFESEVDVSAKAGTAILRVIATDKDDGTNSKLKYSI--VSGNT- 316

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                                 +D  SG +     L    V +Y + V++TD   P    L
Sbjct: 317  ----------------NKSLSVDQNSGVVKVAGRLST-LVHQYALKVQSTDGGEPP---L 356

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +   +  N  + ND  P F+   Y  ++ E   V D  V+  +KA D D G N  I Y 
Sbjct: 357  KTQVDVKYNQKECNDVAPAFNRSLYLATISESTPV-DTAVVT-VKAIDGDSGINKEINYF 414

Query: 191  IIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I         F ID  SG V + K+LDYE    + ++I A D G PS +  T++ + + D
Sbjct: 415  IQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGETRVRVVLMD 474

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDNAPRF  S++  S+  +   G  + R+ A D DEG   +L Y++T     G      
Sbjct: 475  ANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITG----GQGRQHF 530

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ID +SG +  S  +  +    Y L V  +D       +T+               F   
Sbjct: 531  QIDSQSGVITLSRVVGIKQGKVYGLDVEVSDS---VHVSTSKVRVIIGDTNDHSPIFSED 587

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y+V   E+ P GT V  ++ATD D  N  H  Y I   +   +F I + +G     +  
Sbjct: 588  VYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADSGMLYSRLMF 647

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
              +   +    + + ATD GGR    +V++++ D N+  P+FE   Y  ++     +GT 
Sbjct: 648  DRENSSQAIMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYDTTISRSVTMGTP 707

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNKLLDRETMSG 546
            VL+ SA+D D   NA +TY +        V H     F IN  TG I  ++      +  
Sbjct: 708  VLMTSASDPDASSNAALTYVI--------VGHQTPPVFTINAATGVIQVSR---EPEVKS 756

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y   V  +DGG P L     V+I+V++ +     F +  Y   + E+A +G  V+ +   
Sbjct: 757  YNFFVLVKDGGNPLLRSIASVKITVLERDARILHFGKSKYDVTVGENAEMGQIVTGLNLV 816

Query: 607  DADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
                G    + Y +     D  +  F +D ++G +R    LD E +    +  V  +   
Sbjct: 817  -VPGGNPVDVDYRIIKGNNDNNDRKFGVD-STGRVRVIGRLDYE-IRNRYVMIVEANVSA 873

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
              Q +  +V +++ DIND  P F SD     I EN  IG+ +  + A D D G N +V Y
Sbjct: 874  INQIARTVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTY 933

Query: 725  SIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779
            ++   D      F ++   G     + T   LD E  +  +E  +RA    +  L +   
Sbjct: 934  ALVSKDKLVKEKFDIDQHTGW----ITTRGALDREK-QPSFEFQVRATDNGTTRLTSLTT 988

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL 839
            V  +V DVND  P     +   +  +D         + A D D+  +L Y ILSG+    
Sbjct: 989  VRAIVLDVNDTPPKFSQSEFTASVKEDALIGQSVTTITATDEDLNTELYYFILSGDPQAR 1048

Query: 840  ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
              +   TG + +   L+        + +S +DG+    A M++ +
Sbjct: 1049 FGIERKTGVIFVHGSLDRESVGSYDLNISASDGLFTSFAQMKIDI 1093



 Score =  252 bits (616), Expect = 4e-66
 Identities = 194/642 (30%), Positives = 308/642 (47%), Gaps = 45/642 (7%)

Query: 195 NTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND- 252
           N   +F IDS SG++ + V  +D E   SY L I A+D G P  S +T +LI++   N  
Sbjct: 2   NRDNKFIIDSRSGEIFTNVSLVDGE---SYDLTIVAEDNGLPKLSTSTNVLIDVIQGNKP 58

Query: 253 --NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
             NAP F+   +   + E+  I   ++ + A D D     ++TY +     +GN     T
Sbjct: 59  SKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFD---QITYNIA----SGNHGNKFT 111

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG- 369
           ID   G++  +  LDRE ++ Y L V ATDG +     TA+                P  
Sbjct: 112 IDRYGGFITVAHSLDREEKSFYSLRVEATDGYN-----TASVPVTINILDVNDNSPQPAR 166

Query: 370 -QYEVELAEDEPPGTPVVTLTATDADE--DNRLHY---EITGGNTRGRFSITSQNGRGLI 423
            +Y   +AE+   GT V T+ ATD D   +  + Y   +     +   F I S +GR ++
Sbjct: 167 REYRAHVAENSDVGTLVTTVKATDPDAGVNGEVEYCIVQTAKAESASLFKIESHSGR-IL 225

Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
           TV +PLD++  + +VLT+ A+D G   R     V +++ D N++ P F +  + + V   
Sbjct: 226 TV-KPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVS 284

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A  GT +L V ATD D G N+++ YS+ S  +N++++  DQ   +    G ++T      
Sbjct: 285 AKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSLSV-DQNSGVVKVAGRLST------ 337

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
             +  Y L V + DGG P L    DV+ +  + ND  P F + LY A I E   V T+V 
Sbjct: 338 -LVHQYALKVQSTDGGEPPLKTQVDVKYNQKECNDVAPAFNRSLYLATISESTPVDTAVV 396

Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A D D G+N  I+Y +    R    F ID  SGV+   K+LD ES   H++  VA D
Sbjct: 397 TVKAIDGDSGINKEINYFIQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAAD 456

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G P  +    V + + D ND+ P F+       I  ++  G  +  I A DPDEG    
Sbjct: 457 EGKPSLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKK 516

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
           + YSI GG     F ++++ G     ++T+  +      K Y L +  +     +  +V 
Sbjct: 517 LRYSITGGQGRQHFQIDSQSG-----VITLSRVVGIKQGKVYGLDVEVSDSVHVSTSKVR 571

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD 822
           +++ D ND++P+  +  +   ++ + +P G F   V A D D
Sbjct: 572 VIIGDTNDHSPIFSE-DVYKVSFNENYPEGTFVTMVSATDLD 612



 Score =  232 bits (568), Expect = 3e-60
 Identities = 243/905 (26%), Positives = 390/905 (43%), Gaps = 79/905 (8%)

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            VQI + + N+  P F ++ Y  +V EDAPIG  V+ V A   +   N  ITY++     +
Sbjct: 1156 VQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVSRESS-NDVITYAILRGADS 1214

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
                     F I+ + G I  N+ LD ET   Y LTV A D G P L  T+ V ISV D 
Sbjct: 1215 GL-------FSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRISVTDS 1267

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            NDN P F ++ Y+A + E++ +GT V QV ATD D G N +I Y +  +  +   F I  
Sbjct: 1268 NDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSI-AEGNDAKKFKIVE 1326

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
             +GVI+ +  +DRE VA++ LK  A D G PPQ +  +V I++ D+ND+ P F S  LT 
Sbjct: 1327 ETGVIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTDVNDNSPEFSSTNLTT 1386

Query: 695  YISENSPIGTTIGEIRAHDPDE-GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             +SE+S     +  +R HD D  G  A   +++  GD S  F L +     K   V+  D
Sbjct: 1387 VLSESSLPNAAVIHLRPHDRDALGNGAPYQFTLISGDASR-FKLHSNGLITKIGDVSHSD 1445

Query: 754  LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
              Y    +   LV     PP   +V + + + +   + P +    +  N Y      G  
Sbjct: 1446 GQY----RLRVLVADNGHPPQSTEVSITVKIAESKTHPPNVHPLTVYVNLYGSNLNGGVI 1501

Query: 814  GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873
            GRV A D D  D L Y ++S   ++L+++++     T+  + N + P    + VSVTD  
Sbjct: 1502 GRVKATDKD-GDLLHYSLVSSEQSSLLMISD---EGTVRARANIS-PGTYNLNVSVTDKR 1556

Query: 874  NEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYI 933
              + + + + V  IT E   +S+T+RL D++A  F+   L   +  +  ++  P  NI++
Sbjct: 1557 YTVYSGVTVIVLNITPETQEHSVTLRLGDLSAGTFVEKSLEKCLLFIGKLLDVPAVNIHV 1616

Query: 934  FSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQ 993
            +S+Q     + N L+V  + R+     G+       + P +L  ++        +   V+
Sbjct: 1617 WSMQP----SDNDLDVVIAVRK--RRKGM-------FKPLYLTRQLNGSHLAFEKNVGVR 1663

Query: 994  VLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGV 1053
            ++    + C  + C  +  C  V K       V SD V +       S +C C +   G 
Sbjct: 1664 IVTVGLSQCRAQDCPTYLVCSDVYKPELKQIRVMSDHVSYISYEHSRSHSCTCQDKNRG- 1722

Query: 1054 NCETILTKASCEVDGDGSICR---SGSQCVARREGGILCQGCSIDAAYTTAVCELRARSF 1110
             C  I  K +      G  C+    G QC  +      C   +     T+ +    AR+F
Sbjct: 1723 -CGAI-QKCATSPCAPGYKCKDFPEGYQC--KCVDATKCHMDTTGCDDTSCIKGNNARTF 1778

Query: 1111 PVSSFLTFPGLKR---RHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRG 1167
               S++ +  LK    +    + L   T  + G L++      ++D+  LE+        
Sbjct: 1779 NGDSYIRY-RLKETFDQPSRSIGLALKTVKSEGTLVFAA---GQYDYSILEISK------ 1828

Query: 1168 GGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAAD 1226
            G   LRF F    G   ++++ + V DG WH V +E      T+ LD      S      
Sbjct: 1829 GFIQLRFDF----GPGVVSIDWSPVNDGKWHHVAVERQGNHATVTLDYGKHQASGKSPGR 1884

Query: 1227 FGLKYACAN---FTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVG 1283
              +     N   F  KVL +R         +  +  G +   G      +  V  KD   
Sbjct: 1885 MRILNLDGNSIYFGAKVLNSRI--------KRSEGQGVIVENGFKGCMQNLNVNGKDLPM 1936

Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343
              S+ Y        + Y   +    GC    +      C   + C + +    C+C  GH
Sbjct: 1937 TGSNTY-------ASGY--PSNAERGCRTSGACQRPQACPLASRCIETFTDRRCECLPGH 1987

Query: 1344 TGKDC 1348
            +G DC
Sbjct: 1988 SGPDC 1992



 Score =  224 bits (548), Expect = 7e-58
 Identities = 151/508 (29%), Positives = 250/508 (49%), Gaps = 41/508 (8%)

Query: 5    FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            FC+  +++++D ND+ P+FE++ Y+ ++    + GT VL   A+D D   NA + Y I  
Sbjct: 672  FCV-VEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVI-- 728

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQA 123
                                    VF I+  +G +     + RE +V  Y   V   D  
Sbjct: 729  -----------------VGHQTPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGG 767

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
            +P+   L S A++ + +++ +     F +  Y V+V E+  +    ++  +       G 
Sbjct: 768  NPL---LRSIASVKITVLERDARILHFGKSKYDVTVGENAEM--GQIVTGLNLV-VPGGN 821

Query: 184  NSAIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
               + Y II G   N   +F +DS +G V ++  LDYE    Y +++ A +  + ++   
Sbjct: 822  PVDVDYRIIKGNNDNNDRKFGVDS-TGRVRVIGRLDYEIRNRYVMIVEA-NVSAINQIAR 879

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            T +++ + D+ND  P+F +  +  S+ EN+ IG  ++RV A D D G N  +TY +  KD
Sbjct: 880  TVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKD 939

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
                V     ID  +GW+ T G LDRE Q  ++  V ATD G    ++  T         
Sbjct: 940  KL--VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVN 997

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                 F   ++   + ED   G  V T+TATD D +  L+Y I  G+ + RF I  +   
Sbjct: 998  DTPPKFSQSEFTASVKEDALIGQSVTTITATDEDLNTELYYFILSGDPQARFGI--ERKT 1055

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            G+I V   LD +    Y L +SA+D G  +  A ++I+I DAN+  P+   + Y   + E
Sbjct: 1056 GVIFVHGSLDRESVGSYDLNISASD-GLFTSFAQMKIDIEDANDNPPICTQSIYVEHIKE 1114

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSL 508
            + P+G+TVL V ATD+DVG+NA++TYS+
Sbjct: 1115 NTPLGSTVLTVGATDADVGVNAELTYSV 1142



 Score =  163 bits (396), Expect = 2e-39
 Identities = 111/302 (36%), Positives = 162/302 (53%), Gaps = 28/302 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND +P F    Y AS+ E    G+ VL + A D D G N  V Y   LV+ D L
Sbjct: 884  VQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYA--LVSKDKL 941

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V++ F ID  +G + TR +LDREK   +   V+ATD     + RL
Sbjct: 942  ---------------VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNG---TTRL 983

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +S  T+   ++D ND  P+FS+  +T SV ED  +  +  +  I ATD D+  N+ + Y 
Sbjct: 984  TSLTTVRAIVLDVNDTPPKFSQSEFTASVKEDALIGQS--VTTITATDEDL--NTELYYF 1039

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ G+ Q +F I+  +G + +  +LD E V SY L I A DG     ++  Q+ I+I D 
Sbjct: 1040 ILSGDPQARFGIERKTGVIFVHGSLDRESVGSYDLNISASDG---LFTSFAQMKIDIEDA 1096

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-TGNVDLPI 309
            NDN P    S++ E + EN P+G +++ V A DAD GVNAELTY++  + + T  VD  +
Sbjct: 1097 NDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGFGTFAVDKNV 1156

Query: 310  TI 311
             I
Sbjct: 1157 QI 1158



 Score =  157 bits (380), Expect = 2e-37
 Identities = 133/486 (27%), Positives = 214/486 (44%), Gaps = 43/486 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            QI VL+ ND  P F    Y  +V E A  G  V+ ++A  ++   N  + Y I L  AD+
Sbjct: 1157 QIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVSRE-SSNDVITYAI-LRGADS 1214

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               +F ID ++G +     LD E    YT+ V+A+D   PV   
Sbjct: 1215 ------------------GLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPV--- 1253

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L ST+ + +++ D NDN P+FSEK Y+  VDE+ ++     + ++ ATD D G N+ I+Y
Sbjct: 1254 LRSTSYVRISVTDSNDNGPEFSEKRYSAKVDENSAL--GTFVLQVFATDRDSGTNAQIKY 1311

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I  GN   +F I   +G + +   +D E+V SYRL +RAQD G P +   T + I + D
Sbjct: 1312 SIAEGNDAKKFKIVEETGVIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTD 1371

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTYTMTDKDYTGNVDLP 308
            VNDN+P F ++     +SE+     +++ ++ +D D  G  A   +T+   D      L 
Sbjct: 1372 VNDNSPEFSSTNLTTVLSESSLPNAAVIHLRPHDRDALGNGAPYQFTLISGD-ASRFKL- 1429

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
                  +G +   G +   +  +Y+L V   D G PP+S   +                P
Sbjct: 1430 ----HSNGLITKIGDVS-HSDGQYRLRVLVADNGHPPQSTEVSITVKIAESKTHPPNVHP 1484

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
                V L      G  +  + ATD D D  LHY +          I+ +   G +     
Sbjct: 1485 LTVYVNLYGSNLNGGVIGRVKATDKDGD-LLHYSLVSSEQSSLLMISDE---GTVRARAN 1540

Query: 429  LDFKQERRYVLTVSATDSGGR--SDTAMVQINIT-DANNYAPVFENAPYTASVFEDAPIG 485
            +       Y L VS TD      S   ++ +NIT +   ++        +A  F +  + 
Sbjct: 1541 I---SPGTYNLNVSVTDKRYTVYSGVTVIVLNITPETQEHSVTLRLGDLSAGTFVEKSLE 1597

Query: 486  TTVLVV 491
              +L +
Sbjct: 1598 KCLLFI 1603



 Score =  144 bits (349), Expect = 9e-34
 Identities = 109/384 (28%), Positives = 172/384 (44%), Gaps = 19/384 (4%)

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            + + +++ ND  P+FS   Y  +V ED  + +   + +++A   +  +N  I YAI+ G 
Sbjct: 1156 VQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNE--VVRVRAVSRE-SSNDVITYAILRGA 1212

Query: 196  TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
                FSID  +G + + + LDYE  + Y L + A D G P   +T+ + I++ D NDN P
Sbjct: 1213 DSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRISVTDSNDNGP 1272

Query: 256  RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
             F    +   V EN  +G  +++V A D D G NA++ Y++ +    GN      I   +
Sbjct: 1273 EFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSIAE----GNDAKKFKIVEET 1328

Query: 316  GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            G +  SG +DRE  A Y+L V A D G PP+ A                 F        L
Sbjct: 1329 GVIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTDVNDNSPEFSSTNLTTVL 1388

Query: 376  AEDEPPGTPVVTLTATDADE-DNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
            +E   P   V+ L   D D   N   Y+ T       RF + S    GLIT    +    
Sbjct: 1389 SESSLPNAAVIHLRPHDRDALGNGAPYQFTLISGDASRFKLHS---NGLITKIGDVS-HS 1444

Query: 434  ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
            + +Y L V   D+G   +S    + + I ++  + P         +++     G  +  V
Sbjct: 1445 DGQYRLRVLVADNGHPPQSTEVSITVKIAESKTHPPNVHPLTVYVNLYGSNLNGGVIGRV 1504

Query: 492  SATDSDVGINAQITYSL-SSEISN 514
             ATD D  +   + YSL SSE S+
Sbjct: 1505 KATDKDGDL---LHYSLVSSEQSS 1525



 Score =  130 bits (314), Expect = 2e-29
 Identities = 97/316 (30%), Positives = 144/316 (45%), Gaps = 14/316 (4%)

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD---QQFVINPQTGA-ITTNKLL 539
            +G+  L +SA+D      AQ+   +     N  +       +    N   G+ + T    
Sbjct: 1069 VGSYDLNISASDGLFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGAT 1128

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D +      LT +    G  + +   +V+I V+++ND  P F   +Y  N+ EDA +G  
Sbjct: 1129 DADVGVNAELTYSVFGQGFGTFAVDKNVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNE 1188

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V +V A   +   N  I Y +  +  + G F ID  +G I  N+ LD E+   + L   A
Sbjct: 1189 VVRVRAVSRE-SSNDVITYAI-LRGADSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEA 1246

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D G P   ST  V I + D ND+ P F     +  + ENS +GT + ++ A D D G N
Sbjct: 1247 SDAGPPVLRSTSYVRISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTN 1306

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776
            A + YSI  G+D+  F +    G  K       D+D E     Y L +RA     PP   
Sbjct: 1307 AQIKYSIAEGNDAKKFKIVEETGVIKVS----GDIDREEV-ASYRLKVRAQDQGLPPQVA 1361

Query: 777  DVRVEILVTDVNDNAP 792
            D  V+I VTDVNDN+P
Sbjct: 1362 DTVVDIEVTDVNDNSP 1377



 Score = 68.5 bits (160), Expect = 7e-11
 Identities = 76/313 (24%), Positives = 122/313 (38%), Gaps = 36/313 (11%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEG---HTGKDCADST----GPPWR-FGGDGML--- 1364
            +C+++PC  G +C D  + Y C C +    H      D T    G   R F GD  +   
Sbjct: 1728 KCATSPCAPGYKCKDFPEGYQCKCVDATKCHMDTTGCDDTSCIKGNNARTFNGDSYIRYR 1787

Query: 1365 ---SFNPLLRPIQLPWLNALSIRTR-----QRDAFVMSIQLKSGLLHYSYNGETMYLPMA 1416
               +F+   R I L      S  T      Q D  ++ I      L + +    + +  +
Sbjct: 1788 LKETFDQPSRSIGLALKTVKSEGTLVFAAGQYDYSILEISKGFIQLRFDFGPGVVSIDWS 1847

Query: 1417 TLSDGAWHRIEIKWLGTDISVTVDYGLRTV------LMPMLANKIQGQYIG-KILIGGLD 1469
             ++DG WH + ++  G   +VT+DYG           M +L       Y G K+L   + 
Sbjct: 1848 PVNDGKWHHVAVERQGNHATVTLDYGKHQASGKSPGRMRILNLDGNSIYFGAKVLNSRIK 1907

Query: 1470 TTAGLLASDVGFFEGCIQDVRI-GTAQSLLNRPTVR----ENVRDGCQSRADCML-SICP 1523
             + G        F+GC+Q++ + G    +    T       N   GC++   C     CP
Sbjct: 1908 RSEGQGVIVENGFKGCMQNLNVNGKDLPMTGSNTYASGYPSNAERGCRTSGACQRPQACP 1967

Query: 1524 PYSKCVTSWDSSTCTCEAGRVGPQCVS--ACELGPCGAARCVPDQTPKGYSCACE-PGYT 1580
              S+C+ ++    C C  G  GP C +   C   PC       D++  GYS   + P   
Sbjct: 1968 LASRCIETFTDRRCECLPGHSGPDCKAYIKCSGEPCQNRGVCVDKS-DGYSSMYDGPQVP 2026

Query: 1581 LTTSGCIESGKEE 1593
              +S  + S  EE
Sbjct: 2027 KRSSSLMSSSDEE 2039



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 3/55 (5%)

Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT--LTTSGC 1586
            S +CTC+    G   +  C   PC       D  P+GY C C       + T+GC
Sbjct: 1711 SHSCTCQDKNRGCGAIQKCATSPCAPGYKCKD-FPEGYQCKCVDATKCHMDTTGC 1764


>SB_45916| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 1774

 Score =  341 bits (838), Expect = 5e-93
 Identities = 265/805 (32%), Positives = 384/805 (47%), Gaps = 66/805 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV + NDH+P+F        + E  + GTTV   +A D+D+G    V Y         L
Sbjct: 898  LNVTNTNDHAPIFNQSFVPLFIPENTTVGTTVYHAQAYDRDLGTYGHVTYQ--------L 949

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P  A            D F ++  +G +    SLDRE  A Y+V V A+D       + 
Sbjct: 950  IPGRAW-----------DTFAVNKTTGDIKVTRSLDRESNASYSVTVMASD------GKF 992

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +   I V+I D ND YP FS + Y+V++ E+ S    PV+ ++ A D D G+NS + Y+
Sbjct: 993  QAFLEIDVHIQDINDQYPVFSPQNYSVAISEE-SWVRLPVL-QVTAVDMDSGSNSQVTYS 1050

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIR 248
            I+ GN+   FSID  +G + + +TLD+E  RS+ L ++A+D G P+    +   + INI 
Sbjct: 1051 IVDGNSS--FSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINIT 1108

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P F    +  S++E+V  G     V+A DAD G NA+L+Y++ D+D    V   
Sbjct: 1109 DENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADSGKNAKLSYSIPDED----VRKT 1164

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              +D  +G +   G +DRE    Y  +V  TD G  PR   A               F P
Sbjct: 1165 FAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRP 1224

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y V ++E    GT +V + A D D   +  + Y I  GN    F I      G I + 
Sbjct: 1225 QNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHIDSGNKESIFDIED----GTIVLN 1280

Query: 427  QPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
              LD +   +Y L + ATD+G       D A+V I I D N+  P F  + Y+ ++ ED 
Sbjct: 1281 GTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDT 1340

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             IGT VL V A+D D+G NA + Y + +  +++      + F +N  TGAI+T   LD E
Sbjct: 1341 SIGTQVLSVYASDKDLGSNAHVQYFIIASANDDI----KRVFDVNKTTGAISTTSNLDFE 1396

Query: 543  TMSG-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            + +  +   V ARD G P+L   T VEI V DVNDN PVF       ++ E+  V ++V 
Sbjct: 1397 SANNRFQFQVEARDNGKPALYSRTTVEIMVTDVNDNRPVFVGLPRDISVNENLPVKSTVL 1456

Query: 602  QVGATDADVGLNGRIHYELDPKDREEG-------SFVIDPASGVIRTNKALDRESVATHD 654
               A D D G N  + Y +       G       +F I+  +G I T K LDRE++A + 
Sbjct: 1457 IAHAHDEDSGSNSDVRYNITHTYGSRGDIHPDDRTFDIETVTGRIFTAKQLDRENIAYYI 1516

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L   A D G     +   + I++ D ND+ P          I E+SP+ TTI    A+D 
Sbjct: 1517 LVLKACDLGRSRLCTNANITIRLRDKNDNRPALYLP-KQVNIREDSPVNTTIFTAYANDS 1575

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQ----GSDKAELVTMVDLDYESPRKKYELVIRAA 770
            D G NA + Y IK   D++   L          D   L     LD E    +Y++ I A 
Sbjct: 1576 DTGENARIIYDIKNVTDNHGHVLNPYSIFGIKPDSGRLFINRPLDRERV-SRYDVTIEAR 1634

Query: 771  S---PPLWNDVRVEILVTDVNDNAP 792
                 P  +   V I+V DVNDN P
Sbjct: 1635 DGEITPHSSQGTVAIVVDDVNDNNP 1659



 Score =  318 bits (782), Expect = 3e-86
 Identities = 224/732 (30%), Positives = 344/732 (46%), Gaps = 47/732 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND  PVF  Q Y  ++ E +     VL + A D D G N++V Y+I        
Sbjct: 1000 VHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIV------- 1052

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               D               F ID  +G ++   +LD E    + + V+A D   P     
Sbjct: 1053 ---DGNSS-----------FSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVS- 1097

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
               A + +NI D+NDN P F +++Y  S+ ED++     V   ++A DAD G N+ + Y+
Sbjct: 1098 RDYAYVTINITDENDNNPVFDKRSYNFSITEDVA--KGTVFGFVRANDADSGKNAKLSYS 1155

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I   + +  F++D ++G++S+V  +D E+   Y  V+   D GS  R     + + ++DV
Sbjct: 1156 IPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDV 1215

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F    +   +SE   +G  IV V A+D D G NA +TY +     +GN +    
Sbjct: 1216 NDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHID----SGNKE--SI 1269

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFMP 368
             D   G +  +G LDRE   +Y L + ATD G+PP+ +   A               F  
Sbjct: 1270 FDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNA 1329

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE---ITGGNTRGRFSITSQNGRGLITV 425
              Y V ++ED   GT V+++ A+D D  +  H +   I   N   +         G I+ 
Sbjct: 1330 SVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAIST 1389

Query: 426  AQPLDFKQ-ERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDA 482
               LDF+    R+   V A D+G  +      V+I +TD N+  PVF   P   SV E+ 
Sbjct: 1390 TSNLDFESANNRFQFQVEARDNGKPALYSRTTVEIMVTDVNDNRPVFVGLPRDISVNENL 1449

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH-HDQQFVINPQTGAITTNKLLDR 541
            P+ +TVL+  A D D G N+ + Y+++    +    H  D+ F I   TG I T K LDR
Sbjct: 1450 PVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSRGDIHPDDRTFDIETVTGRIFTAKQLDR 1509

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E ++ Y+L + A D G   L    ++ I + D NDN P         NI ED+ V T++ 
Sbjct: 1510 ENIAYYILVLKACDLGRSRLCTNANITIRLRDKNDNRPALYLP-KQVNIREDSPVNTTIF 1568

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGS-------FVIDPASGVIRTNKALDRESVATHD 654
               A D+D G N RI Y++       G        F I P SG +  N+ LDRE V+ +D
Sbjct: 1569 TAYANDSDTGENARIIYDIKNVTDNHGHVLNPYSIFGIKPDSGRLFINRPLDRERVSRYD 1628

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            +   A DG   P SS   V I ++D+ND+ P   S         ++    ++  +   D 
Sbjct: 1629 VTIEARDGEITPHSSQGTVAIVVDDVNDNNPKCNSSTSKVDYMISTREYESLLTLHVCDN 1688

Query: 715  DEGPNAVVHYSI 726
            DEG N+VV ++I
Sbjct: 1689 DEGNNSVVEFTI 1700



 Score =  290 bits (711), Expect = 1e-77
 Identities = 212/719 (29%), Positives = 338/719 (47%), Gaps = 53/719 (7%)

Query: 98   ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157
            AL+T   LD E+ +R+ + + AT+       +L++  T+ +N+ + ND+ P F++    +
Sbjct: 862  ALITAKPLDHEQNSRHELTITATN----TDTKLATVITVTLNVTNTNDHAPIFNQSFVPL 917

Query: 158  SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY 217
             + E+ +V     +   +A D D+G    + Y +I G     F+++  +GD+ + ++LD 
Sbjct: 918  FIPENTTV--GTTVYHAQAYDRDLGTYGHVTYQLIPGRAWDTFAVNKTTGDIKVTRSLDR 975

Query: 218  EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
            E   SY + + A DG   +     ++ ++I+D+ND  P F    +  ++SE   +   ++
Sbjct: 976  ESNASYSVTVMASDGKFQA---FLEIDVHIQDINDQYPVFSPQNYSVAISEESWVRLPVL 1032

Query: 278  RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337
            +V A D D G N+++TY++ D    GN     +IDP +G +     LD E    + L V 
Sbjct: 1033 QVTAVDMDSGSNSQVTYSIVD----GNSS--FSIDPNTGQIIVHRTLDFEVTRSFILRVQ 1086

Query: 338  ATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD- 394
            A D G P   +   A               F    Y   + ED   GT    + A DAD 
Sbjct: 1087 ARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADS 1146

Query: 395  -EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSD 451
             ++ +L Y I   + R  F++    G   ++V   +D ++   Y   V  TD G   R  
Sbjct: 1147 GKNAKLSYSIPDEDVRKTFAVDEITGN--LSVVGDIDRERTGIYSFVVVVTDHGSSPRVG 1204

Query: 452  TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
             A+V + + D N+  P+F    YT  + E   +GT ++ V A D D+G NA ITY + S 
Sbjct: 1205 FAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHIDS- 1263

Query: 512  ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-VPSLS-DTTDVEI 569
                     +++ + + + G I  N  LDRE M  Y L + A D G  P LS D   V I
Sbjct: 1264 --------GNKESIFDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVI 1315

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREE 627
            ++ D+NDN P F   +Y+ NI ED  +GT V  V A+D D+G N  + Y +     D  +
Sbjct: 1316 TIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIK 1375

Query: 628  GSFVIDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
              F ++  +G I T   LD ES       +  A D G P   S   V I + D+ND+ PV
Sbjct: 1376 RVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSRTTVEIMVTDVNDNRPV 1435

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-----KGGD---DSNSFSLE 738
            F        ++EN P+ +T+    AHD D G N+ V Y+I       GD   D  +F +E
Sbjct: 1436 FVGLPRDISVNENLPVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSRGDIHPDDRTFDIE 1495

Query: 739  TRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM 794
            T  G     + T   LD E+    Y LV++A       L  +  + I + D NDN P +
Sbjct: 1496 TVTG----RIFTAKQLDREN-IAYYILVLKACDLGRSRLCTNANITIRLRDKNDNRPAL 1549



 Score =  222 bits (542), Expect = 4e-57
 Identities = 174/625 (27%), Positives = 285/625 (45%), Gaps = 36/625 (5%)

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA-ELTYTMTDKDYTGNV 305
            + +V D+ P F    + + V E   IG  ++ ++         A  ++ T+T  +  G  
Sbjct: 791  VLEVFDSKPAFRERHYSKEVLETTEIGEVLLGLRFSALGRFHRATSVSLTVTKGNKGGIF 850

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
             +   +      + T+  LD E  ++++L +TAT+  D   +   T              
Sbjct: 851  MITPNVSREYAALITAKPLDHEQNSRHELTITATNT-DTKLATVITVTLNVTNTNDHAPI 909

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLI 423
            F      + + E+   GT V    A D D     H  Y++  G     F++    G   I
Sbjct: 910  FNQSFVPLFIPENTTVGTTVYHAQAYDRDLGTYGHVTYQLIPGRAWDTFAVNKTTGD--I 967

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
             V + LD +    Y +TV A+D G       + ++I D N+  PVF    Y+ ++ E++ 
Sbjct: 968  KVTRSLDRESNASYSVTVMASD-GKFQAFLEIDVHIQDINDQYPVFSPQNYSVAISEESW 1026

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            +   VL V+A D D G N+Q+TYS         +   +  F I+P TG I  ++ LD E 
Sbjct: 1027 VRLPVLQVTAVDMDSGSNSQVTYS---------IVDGNSSFSIDPNTGQIIVHRTLDFEV 1077

Query: 544  MSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
               ++L V ARD G P+L   D   V I++ D NDN PVF ++ Y  +I ED   GT   
Sbjct: 1078 TRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFG 1137

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             V A DAD G N ++ Y +  +D  + +F +D  +G +     +DRE    +    V  D
Sbjct: 1138 FVRANDADSGKNAKLSYSIPDEDVRK-TFAVDEITGNLSVVGDIDRERTGIYSFVVVVTD 1196

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             G+ P+    +V ++++D+ND+ P+F     T  ISE + +GT I  + AHD D GPNA+
Sbjct: 1197 HGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNAL 1256

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPLWND 777
            + Y I  G+  + F +E         +V    LD E    +Y L I A      P L  D
Sbjct: 1257 ITYHIDSGNKESIFDIE------DGTIVLNGTLDRE-VMDQYTLGILATDNGEPPQLSRD 1309

Query: 778  VRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSG 834
              + ++ + D+NDN P         N  +D         V A D D+     +QY I++ 
Sbjct: 1310 PAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIAS 1369

Query: 835  NNANL---ILLNETTGSMTLSPQLN 856
             N ++     +N+TTG+++ +  L+
Sbjct: 1370 ANDDIKRVFDVNKTTGAISTTSNLD 1394



 Score =  216 bits (528), Expect = 2e-55
 Identities = 166/583 (28%), Positives = 282/583 (48%), Gaps = 53/583 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+ P+F  Q Y   + EG S GT ++ + A D+DIG NA + Y I     D+ 
Sbjct: 1210 VQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHI-----DSG 1264

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N E               +F I+   G ++   +LDRE + +YT+ + ATD   P   +L
Sbjct: 1265 NKES--------------IFDIE--DGTIVLNGTLDREVMDQYTLGILATDNGEP--PQL 1306

Query: 131  SSTATIHVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S    I V  I+D NDNYP+F+   Y+V++ ED S+     +  + A+D D+G+N+ ++Y
Sbjct: 1307 SRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQ--VLSVYASDKDLGSNAHVQY 1364

Query: 190  AIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI 245
             II     + +  F ++  +G +S    LD+E   + ++  + A+D G P+  + T + I
Sbjct: 1365 FIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSRTTVEI 1424

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGN 304
             + DVNDN P F       SV+EN+P+  +++   A+D D G N+++ Y +T      G+
Sbjct: 1425 MVTDVNDNRPVFVGLPRDISVNENLPVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSRGD 1484

Query: 305  V---DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +   D    I+  +G ++T+ QLDRE  A Y L++ A D G       A           
Sbjct: 1485 IHPDDRTFDIETVTGRIFTAKQLDRENIAYYILVLKACDLGRSRLCTNANITIRLRDKND 1544

Query: 362  XX-XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-----GNTRGRFS 413
                 ++P Q  V + ED P  T + T  A D+D  E+ R+ Y+I       G+    +S
Sbjct: 1545 NRPALYLPKQ--VNIREDSPVNTTIFTAYANDSDTGENARIIYDIKNVTDNHGHVLNPYS 1602

Query: 414  ITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470
            I   +   G + + +PLD ++  RY +T+ A D      S    V I + D N+  P   
Sbjct: 1603 IFGIKPDSGRLFINRPLDRERVSRYDVTIEARDGEITPHSSQGTVAIVVDDVNDNNPKCN 1662

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
            ++              ++L +   D+D G N+ + ++++  +++      + +F ++   
Sbjct: 1663 SSTSKVDYMISTREYESLLTLHVCDNDEGNNSVVEFTIARVVTDSEC---EGRFEVSSNG 1719

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                T  L+       Y +TVT RD G P L+ T DV ++VV+
Sbjct: 1720 TLYNTVPLVHA---CKYTITVTVRDWGEPRLTGTCDVIVNVVE 1759



 Score =  140 bits (338), Expect = 2e-32
 Identities = 125/416 (30%), Positives = 198/416 (47%), Gaps = 29/416 (6%)

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            P F    Y+  V E   IG  +L +    S +G   + T S+S  ++     +    F+I
Sbjct: 799  PAFRERHYSKEVLETTEIGEVLLGLRF--SALGRFHRAT-SVSLTVTK---GNKGGIFMI 852

Query: 527  NPQTG----AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             P       A+ T K LD E  S + LT+TA +     L+    V ++V + ND+ P+F 
Sbjct: 853  TPNVSREYAALITAKPLDHEQNSRHELTITATNTDT-KLATVITVTLNVTNTNDHAPIFN 911

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
            Q      I E+  VGT+V    A D D+G  G + Y+L P  R   +F ++  +G I+  
Sbjct: 912  QSFVPLFIPENTTVGTTVYHAQAYDRDLGTYGHVTYQLIP-GRAWDTFAVNKTTGDIKVT 970

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            ++LDRES A++ +  +A DG      + + + + I+DIND  PVF     +  ISE S +
Sbjct: 971  RSLDRESNASYSVTVMASDGKF---QAFLEIDVHIQDINDQYPVFSPQNYSVAISEESWV 1027

Query: 703  GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
               + ++ A D D G N+ V YSI  G+  +SFS++   G    +++    LD+E  R  
Sbjct: 1028 RLPVLQVTAVDMDSGSNSQVTYSIVDGN--SSFSIDPNTG----QIIVHRTLDFEVTRS- 1080

Query: 763  YELVIRA---ASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817
            + L ++A     P L +     V I +TD NDN PV       F+  +D      FG V 
Sbjct: 1081 FILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVR 1140

Query: 818  AYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            A DAD     KL Y I   +      ++E TG++++   ++     + +  V VTD
Sbjct: 1141 ANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTD 1196



 Score =  112 bits (269), Expect = 4e-24
 Identities = 104/354 (29%), Positives = 161/354 (45%), Gaps = 40/354 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV--TA 67
            +I V D ND+ PVF     + SV E     +TVL   A D+D G N++V Y I     + 
Sbjct: 1423 EIMVTDVNDNRPVFVGLPRDISVNENLPVKSTVLIAHAHDEDSGSNSDVRYNITHTYGSR 1482

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              ++P+D               F I+  +G + T   LDRE +A Y +++KA D      
Sbjct: 1483 GDIHPDDR-------------TFDIETVTGRIFTAKQLDRENIAYYILVLKACDLG---R 1526

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             RL + A I + + D NDN P        V++ ED  V  N  I    A D+D G N+ I
Sbjct: 1527 SRLCTNANITIRLRDKNDNRPAL-YLPKQVNIREDSPV--NTTIFTAYANDSDTGENARI 1583

Query: 188  RYAIIG-----GNTQMQFSIDSL---SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
             Y I       G+    +SI  +   SG + + + LD E+V  Y + I A+DG     S+
Sbjct: 1584 IYDIKNVTDNHGHVLNPYSIFGIKPDSGRLFINRPLDRERVSRYDVTIEARDGEITPHSS 1643

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT---- 295
               + I + DVNDN P+  +S  +     +     S++ +   D DEG N+ + +T    
Sbjct: 1644 QGTVAIVVDDVNDNNPKCNSSTSKVDYMISTREYESLLTLHVCDNDEGNNSVVEFTIARV 1703

Query: 296  MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
            +TD +  G  ++       +G +Y +  L      KY + VT  D G+P  + T
Sbjct: 1704 VTDSECEGRFEV-----SSNGTLYNTVPLVH--ACKYTITVTVRDWGEPRLTGT 1750



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 48/214 (22%), Positives = 94/214 (43%), Gaps = 10/214 (4%)

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSL 737
            ++ DS P F     +  + E + IG  +  +R         A  V  ++  G+    F +
Sbjct: 793  EVFDSKPAFRERHYSKEVLETTEIGEVLLGLRFSALGRFHRATSVSLTVTKGNKGGIFMI 852

Query: 738  ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP--LWNDVRVEILVTDVNDNAPVM- 794
                  + A L+T   LD+E    ++EL I A +    L   + V + VT+ ND+AP+  
Sbjct: 853  TPNVSREYAALITAKPLDHEQ-NSRHELTITATNTDTKLATVITVTLNVTNTNDHAPIFN 911

Query: 795  KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLS 852
            + F  +F           +    AYD D+     + Y+++ G   +   +N+TTG + ++
Sbjct: 912  QSFVPLFIPENTTVGTTVY-HAQAYDRDLGTYGHVTYQLIPGRAWDTFAVNKTTGDIKVT 970

Query: 853  PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
              L+       ++ V  +DG  + +A +++ V +
Sbjct: 971  RSLDRESNASYSVTVMASDG--KFQAFLEIDVHI 1002


>SB_5763| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 674

 Score =  332 bits (817), Expect = 2e-90
 Identities = 207/604 (34%), Positives = 324/604 (53%), Gaps = 33/604 (5%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           SG ++  + LDRE    Y + V A +  +   D   +T  +H+ + D  D+ P F+  + 
Sbjct: 78  SGDIIVDSPLDREFKNVYILNVTAANIVAGAQD---TTTQVHITVTDVIDDKPYFNSSSL 134

Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215
           TV + E+ S+  N  + KI A D D+G    I Y+I  G+    F+ID+++G++  V  L
Sbjct: 135 TVKLSENASIGTN--VTKITALDKDIG--DTISYSIANGDPYGLFTIDNVTGEIRTVAEL 190

Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
           D E V  Y L ++A+D  +   S+  ++++ + DVNDN P F    +     E  P G S
Sbjct: 191 DRENVTQYELFVQAKDSVNLV-SDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTS 249

Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQL 334
           I++V+A DAD G NA + Y++ +     NV   +T++  +G +   S QLDRE +  +  
Sbjct: 250 ILQVKAIDADIGDNAAVLYSIVE-----NVTDYVTVNAITGVISLGSSQLDREVEEYFNF 304

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
            + ATD G P +S+TA+              F    Y   + E++P GTPV+ +TA+D D
Sbjct: 305 TIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKD 364

Query: 395 --EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRS 450
              + +L Y +  G    RF+I    G   IT  +PL+ ++   Y LT+ A DS    R 
Sbjct: 365 VGTNAKLSY-VLSGVLYTRFAIDPDTGN--ITTREPLNREETGSYTLTLRAVDSAIRARE 421

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            T  V I +TDAN++ P F  + Y  SV ED  +G TV  V+ TD D+  NA++ Y +SS
Sbjct: 422 GTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISS 481

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
              N ++      F +N  TG I+T   LDRE  + Y L +TA+D G+P+L   T V I+
Sbjct: 482 --GNTSL-----MFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMIT 534

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE---- 626
           + DVNDN+P+F + +Y   + E   + T V QV ATD D G NG+  Y++   D +    
Sbjct: 535 IEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFY 594

Query: 627 -EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            +G F +D  +GV+   + LDRE  + + L  +A D G P  SS+V V+I + D+ND+ P
Sbjct: 595 IDGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLP 654

Query: 686 VFES 689
           + ++
Sbjct: 655 ILQT 658



 Score =  295 bits (724), Expect = 3e-79
 Identities = 204/601 (33%), Positives = 303/601 (50%), Gaps = 30/601 (4%)

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
           +SGD+ +   LD E    Y L + A +  + ++  TTQ+ I + DV D+ P F +S    
Sbjct: 77  VSGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLTV 136

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            +SEN  IG ++ ++ A D D G    ++Y++ + D  G      TID  +G + T  +L
Sbjct: 137 KLSENASIGTNVTKITALDKDIGDT--ISYSIANGDPYGL----FTIDNVTGEIRTVAEL 190

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           DRE   +Y+L V A D  +                       MPG Y +E  E+ P GT 
Sbjct: 191 DRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPG-YTIEYWEESPEGTS 249

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV-AQPLDFKQERRYVLTV 441
           ++ + A DAD  ++  + Y I    T     +T     G+I++ +  LD + E  +  T+
Sbjct: 250 ILQVKAIDADIGDNAAVLYSIVENVTD---YVTVNAITGVISLGSSQLDREVEEYFNFTI 306

Query: 442 SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            ATDSG   +S TA V I + D N+ +PVF N  Y A V E+ P GT VLVV+A+D DVG
Sbjct: 307 RATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVG 366

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            NA+++Y LS  +          +F I+P TG ITT + L+RE    Y LT+ A D  + 
Sbjct: 367 TNAKLSYVLSGVLYT--------RFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIR 418

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
           +   TT V I+V D ND+ P F Q  Y  ++ ED  VG +V +V  TD D+  N R+ Y 
Sbjct: 419 AREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYY 478

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
           +   +     F ++  +G+I T   LDRE  A++ L   A D G P   S   V I IED
Sbjct: 479 ISSGNTSL-MFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIED 537

Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE- 738
           +ND+ P+F        + E+  + T + ++ A DPDEG N    Y I  GD  + F ++ 
Sbjct: 538 VNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDG 597

Query: 739 TRQGSDKAELVTMV-DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794
             Q  +K  ++T    LD E     Y LV+ A     P L + V V I V D+NDN P++
Sbjct: 598 VFQMDNKTGVLTRTRPLDRED-TSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPIL 656

Query: 795 K 795
           +
Sbjct: 657 Q 657



 Score =  274 bits (672), Expect = 7e-73
 Identities = 192/577 (33%), Positives = 279/577 (48%), Gaps = 41/577 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D  D  P F        + E AS GT V  + A D+DIG    + Y+I     D  
Sbjct: 117 ITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSI--ANGDPY 172

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             +F ID  +G + T A LDRE V +Y + V+A D  + VSD L
Sbjct: 173 G-----------------LFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLL 215

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                + V + D NDN P FS   YT+   E+    +   I ++KA DAD+G N+A+ Y+
Sbjct: 216 K----VVVQVEDVNDNPPVFSMPGYTIEYWEE--SPEGTSILQVKAIDADIGDNAAVLYS 269

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           I+  N     ++++++G +SL  + LD E    +   IRA D G PS+S+T  + I + D
Sbjct: 270 IV-ENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVD 328

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           +NDN+P F  + +   V EN P G  ++ V A D D G NA+L+Y ++   YT       
Sbjct: 329 INDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYT-----RF 383

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            IDP +G + T   L+RE    Y L + A D     R  T                F   
Sbjct: 384 AIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQS 443

Query: 370 QYEVELAEDEPPGTPVVTLTATDAD-EDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            Y   + ED   G  V  +  TD D  DN R+ Y I+ GNT   FS+      G+I+   
Sbjct: 444 GYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNETT--GIISTTS 501

Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            LD +Q   Y L ++A D G         V I I D N+  P+F  + Y  ++ E   + 
Sbjct: 502 TLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLK 561

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           T V+ V ATD D G N Q TY +++  +++ V + D  F ++ +TG +T  + LDRE  S
Sbjct: 562 TQVVQVIATDPDEGANGQFTYKITAGDTDD-VFYIDGVFQMDNKTGVLTRTRPLDREDTS 620

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
            Y L V A D G P+LS +  V I+V+D+NDN P+ +
Sbjct: 621 FYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQ 657



 Score =  204 bits (499), Expect = 6e-52
 Identities = 155/474 (32%), Positives = 229/474 (48%), Gaps = 26/474 (5%)

Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDAN 463
           G+  G     S +  G I V  PLD + +  Y+L V+A +  +G +  T  V I +TD  
Sbjct: 64  GDGGGGEDTDSGDVSGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVI 123

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           +  P F ++  T  + E+A IGT V  ++A D D+G    I+YS+++             
Sbjct: 124 DDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSIAN-------GDPYGL 174

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F I+  TG I T   LDRE ++ Y L V A+D  V  +SD   V + V DVNDN PVF  
Sbjct: 175 FTIDNVTGEIRTVAELDRENVTQYELFVQAKDS-VNLVSDLLKVVVQVEDVNDNPPVFSM 233

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
             YT    E++  GTS+ QV A DAD+G N  + Y +   +       ++  +GVI    
Sbjct: 234 PGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSI--VENVTDYVTVNAITGVISLGS 291

Query: 644 A-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
           + LDRE     +    A D G P +SST  V IK+ DIND+ PVF +     Y+ EN P 
Sbjct: 292 SQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPA 351

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
           GT +  + A D D G NA + Y + G   +  F+++     D   + T   L+ E     
Sbjct: 352 GTPVLVVTASDKDVGTNAKLSYVLSGVLYTR-FAIDP----DTGNITTREPLNREETGS- 405

Query: 763 YELVIRAASPPLW---NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
           Y L +RA    +       RV I VTD ND+ P        F+  +D       GRV   
Sbjct: 406 YTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATT 465

Query: 820 DADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           D D+ D  +++Y I SGN + +  +NETTG ++ +  L+       T+ ++  D
Sbjct: 466 DEDINDNARVRYYISSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKD 519



 Score =  127 bits (307), Expect = 1e-28
 Identities = 84/257 (32%), Positives = 123/257 (47%), Gaps = 30/257 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D NDH P F    Y  SVRE    G TV  +  TD+DI  NA V Y I       +
Sbjct: 428 ITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLM 487

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F ++  +G + T ++LDRE+ A YT+++ A D   P    L
Sbjct: 488 -------------------FSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPA---L 525

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S  ++ + I D NDN P FS+  Y V++ E + +     + ++ ATD D GAN    Y 
Sbjct: 526 ESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQ--VVQVIATDPDEGANGQFTYK 583

Query: 191 IIGGNTQMQFSIDSL------SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           I  G+T   F ID +      +G ++  + LD E    Y LV+ A+D G P+ S++  + 
Sbjct: 584 ITAGDTDDVFYIDGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVN 643

Query: 245 INIRDVNDNAPRFYTSL 261
           I + D+NDN P   T +
Sbjct: 644 ITVLDMNDNLPILQTPM 660



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 35/162 (21%), Positives = 66/162 (40%), Gaps = 4/162 (2%)

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW---NDVRVEILV 784
           GG        +T  G    +++    LD E  +  Y L + AA+          +V I V
Sbjct: 61  GGCGDGGGGEDTDSGDVSGDIIVDSPLDREF-KNVYILNVTAANIVAGAQDTTTQVHITV 119

Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844
           TDV D+ P      +     ++        ++ A D D+ D + Y I +G+   L  ++ 
Sbjct: 120 TDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGLFTIDN 179

Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
            TG +    +L+        + V   D VN +  ++++ V++
Sbjct: 180 VTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLLKVVVQV 221


>SB_47886| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 679

 Score =  329 bits (809), Expect = 2e-89
 Identities = 233/717 (32%), Positives = 342/717 (47%), Gaps = 90/717 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +N+LD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I        
Sbjct: 24  VNILDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 75

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +  F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 76  -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 121

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +ST  + + + D NDN P   +    VS+              I ATD D GANSA+ Y+
Sbjct: 122 NSTTAVAIQVGDANDNPPVIQDAVIQVSL--------------ISATDGDAGANSALTYS 167

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I  GN +  FSI++ +G +S+ K LD E    Y L + AQDGG P  ++TT ++I + D 
Sbjct: 168 IAAGNEEGVFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVVIQVGDA 227

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P    ++ Q S+SE   I   +  V A D D G N  L Y++ +    G+  +   
Sbjct: 228 NDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFQIK-- 284

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            D  SG +  +G L    +  Y ++V  TDGG P   + A                    
Sbjct: 285 -DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------ 337

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQ 427
           Y+V + E E     V+ L   ++      H+ ++GGN        S+ S NG  L   + 
Sbjct: 338 YDVSVLEGE-ANVQVMDLKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGST 390

Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           PLD +   ++VL +S T+ G       V +N+ D N+  P+F++  +  SV E   +GT 
Sbjct: 391 PLDRETAAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV 450

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            L VSATD D G N+ +TYS+       A  + +  F IN +TGAI+  K LDRET   Y
Sbjct: 451 FLTVSATDGDAGSNSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQY 503

Query: 548 LLTVTARDGGVPSLSDTT--------------------------DVEISVVDVNDNEPVF 581
            LTV A+DGG P L+ TT                          +V ++V+D+ND  P+F
Sbjct: 504 TLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSEVTVNVLDINDETPLF 563

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
           +   +  ++ E   +GT    V ATD D G N  + Y +     EEG F I+  +G I  
Sbjct: 564 QSPSFNVSVNEIERLGTVFLTVLATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISV 622

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
            K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV +   +   +SE
Sbjct: 623 AKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 679



 Score =  297 bits (729), Expect = 8e-80
 Identities = 226/712 (31%), Positives = 340/712 (47%), Gaps = 81/712 (11%)

Query: 120 TDQASPVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
           +++ S +S+ LS  A  + VNI+D ND  P F   ++ VSV+E   +    V   + ATD
Sbjct: 5   SNKNSLISEDLSYIALQVTVNILDINDETPLFQSPSFNVSVNEIERL--GTVFLTVSATD 62

Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
            D GANSA+ Y+I  GN +  FSI++ +G +S+ K LD E    Y L + AQDGG P  +
Sbjct: 63  GDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLN 122

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           +TT + I + D NDN P    ++ Q S+            + A D D G N+ LTY++  
Sbjct: 123 STTAVAIQVGDANDNPPVIQDAVIQVSL------------ISATDGDAGANSALTYSIA- 169

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
               GN +   +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T         
Sbjct: 170 ---AGNEEGVFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVVIQVGD 226

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416
                        +V L+E     TPV T+ A+D D   + RL Y I  G   G F I  
Sbjct: 227 ANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQI-K 284

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPY 474
            +  G I++A  L + Q   Y++ V+ TD G  +    AMV I++T      P   N  Y
Sbjct: 285 DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PKPRNLTY 338

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
             SV E       V+ +   +S   ++    T+  SS             F IN  T   
Sbjct: 339 DVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDSS----------GSMFSIN-GTNLR 386

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
             +  LDRET + ++L ++  +GG  ++     V ++V+D+ND  P+F+   +  ++ E 
Sbjct: 387 VGSTPLDRETAAQHVLDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEI 444

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
             +GT    V ATD D G N  + Y +     EEG F I+  +G I   K LDRE+   +
Sbjct: 445 ERLGTVFLTVSATDGDAGSNSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQY 503

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV--------------------------F 687
            L  +A DGG PP +ST  V I++ D ND+PPV                          F
Sbjct: 504 TLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSEVTVNVLDINDETPLF 563

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
           +S      ++E   +GT    + A D D G N+ + YSI  G++   FS+  + G+    
Sbjct: 564 QSPSFNVSVNEIERLGTVFLTVLATDGDAGANSALTYSIAAGNEEGFFSINNKTGA---- 619

Query: 748 LVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796
           +     LD E+ R +Y L + A     PPL +   V I V D NDN PV++D
Sbjct: 620 ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 670



 Score =  231 bits (565), Expect = 6e-60
 Identities = 195/664 (29%), Positives = 297/664 (44%), Gaps = 74/664 (11%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           Q+ +NI D+ND  P F +  F  SV+E   +G   + V A D D G N+ LTY++     
Sbjct: 21  QVTVNILDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA---- 76

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            GN +   +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T            
Sbjct: 77  AGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAND 136

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                     +V L          ++ T  DA  ++ L Y I  GN  G FSI   N  G
Sbjct: 137 NPPVIQDAVIQVSL----------ISATDGDAGANSALTYSIAAGNEEGVFSIN--NKTG 184

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479
            I+VA+ LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    S+ 
Sbjct: 185 AISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVVIQVGDANDNPPVIQDAVIQVSLS 244

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E A I T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+   +L
Sbjct: 245 ETAAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGML 297

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
                + Y++ V   DGG P+L     V   V+DV    P  +   Y  +++E       
Sbjct: 298 SYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKPRNLTYDVSVLEGE-ANVQ 350

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V  +   ++   ++G      D      GS      + +   +  LDRE+ A H L    
Sbjct: 351 VMDLKPAESHFNVSGGNFTFFD----SSGSMFSINGTNLRVGSTPLDRETAAQHVLDISL 406

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            +GGT      V V + + DIND  P+F+S      ++E   +GT    + A D D G N
Sbjct: 407 TEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGSN 464

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
           + + YSI  G++   FS+  + G+    +     LD E+ R +Y L + A     PPL +
Sbjct: 465 SALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNS 519

Query: 777 DVRVEILVTDVNDNAPVMKDFQI------IFNNYKDCFPVGPFGRVPAY----------- 819
              V I V D NDN PV++D  I      +  N  D     P  + P++           
Sbjct: 520 TTAVAIQVGDANDNPPVIQDAVIQVSLSEVTVNVLDINDETPLFQSPSFNVSVNEIERLG 579

Query: 820 -----------DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
                      DA     L Y I +GN      +N  TG+++++ QL+       T+ V 
Sbjct: 580 TVFLTVLATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVM 639

Query: 869 VTDG 872
             DG
Sbjct: 640 AQDG 643


>SB_51779| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 3610

 Score =  304 bits (746), Expect = 7e-82
 Identities = 280/983 (28%), Positives = 441/983 (44%), Gaps = 88/983 (8%)

Query: 9    QQINVLDCND-HSPVFEMQQYEASVREGASSGTTVLTLKATDQDI----------GKNAE 57
            Q + V+D      P+FE   Y  SVRE A+ GTT+  ++A  Q+             NA+
Sbjct: 1621 QTLVVIDVTTVEPPMFERHLYNISVRENAAVGTTIGQIRAVSQNNRPIMYQPLHENPNAK 1680

Query: 58   VEYTIELVTADTLNPEDAXXXXXXXXXXVQDV--FRIDGRSGALLTRASLDREKVARYTV 115
             E  IE+ T   +               +QD   F ID + G +      DRE+ +RY++
Sbjct: 1681 EEIGIEIDTGSIVT-SSKLDYESVNNYELQDYQKFTIDTQRGTIRNAVVFDREEESRYSL 1739

Query: 116  LVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK 175
               ATD  +P     S+   + ++++D ND  P F +K    SV ED  +  +  + K  
Sbjct: 1740 TAIATDAGTPP---FSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSS--VYKAV 1794

Query: 176  ATDADVGANSAIRYAIIGGNTQMQFSI------DSLSGDVSLVKTLDYEQVRSYRLVIRA 229
              D+D+  ++++ + I GGN + +F +       S  G V ++  LDYE  R ++L +  
Sbjct: 1795 ILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQREFKLRLTI 1854

Query: 230  QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-V 288
             DG +   S+   L I + D NDNAP F   +++ S+ E  P G S+V V A D D   V
Sbjct: 1855 SDGKT---SDFGFLTIKVTDANDNAPLFSKLVYEVSLREESPAGTSVVTVSAIDIDSPPV 1911

Query: 289  NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRS 347
               +TY++   D  G  +    I   +G +      LDRE    Y   V A+DG +  R+
Sbjct: 1912 QEAITYSI---DKRG--EQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGRA 1966

Query: 348  ATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406
                              F P   Y   L E+   GT V  + A D D+ N       GG
Sbjct: 1967 EVMVTLVDINDQAP----FFPNPPYYAALFENRAIGTNVTVMQAIDNDDPN------AGG 2016

Query: 407  NTRGRFSITSQNG--------RGLITVAQPLDFK--QERRYVLTVSATDSG--GRSDTAM 454
            NT+  +S+   NG         GL+T  + +D +  QE  + +TV ATD G    S T +
Sbjct: 2017 NTKIIYSLEDNNGGYVTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQPALSGTTV 2076

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            +Q+   D N++ P F    Y ASV E    G  V  V ATD D G N  + Y +     N
Sbjct: 2077 LQVFFEDENDHKPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQ--GN 2134

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVV 572
            E  A     F I P+TG +  + +LD E+   Y L V   D G+P L   +   V +++ 
Sbjct: 2135 EPYA-----FFIEPRTGVVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNIT 2189

Query: 573  DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
            D N + P F Q+++ A++ ED  +G SV  + ATD D       H  L     EE  F I
Sbjct: 2190 DDNTHPPRFAQKVHEASVREDVPLGYSVLTIKATDIDTV--DSFHRFLISSGDEENMFTI 2247

Query: 633  -----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
                 +  + +I     LDRE  + +++  V  D  T  QS   IV I + D ND+ P F
Sbjct: 2248 TESESEKMTAIITVRGKLDRERKSFYNMIVVVND--TSGQSDECIVKITVTDANDNGPHF 2305

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSL-ETRQGSDK 745
            +    + ++ EN      +  I A DPD   N     +++     S+ F + ++   S+ 
Sbjct: 2306 QPSYFSGFVRENIDSEQFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNT 2365

Query: 746  AELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
            A++      D E     Y+L++ A+    P +WN   + + V DVN++ P+  +  II N
Sbjct: 2366 AQVFAYGTFDREL-TPFYKLLVNASDSGRPAMWNHTYIYVDVLDVNEHEPIDGNNTIIVN 2424

Query: 803  NYKDCFPVGPFGRVPAYDADVTDKLQ-YRILSGNNANLILLNETTGSMTLSP--QLNTNV 859
                 F  G  GR    D D    +  Y++ S +    + +N  TG++T SP   L   V
Sbjct: 2425 ALDGAFAGGVIGRPYYQDDDYNGDINVYKMTSQSPGAYLDMNSATGAITASPGIPLGEYV 2484

Query: 860  PKLATME-VSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFI 917
             K + +E V   D     ++   ++ VR ++ + +L S T+RL DM           + +
Sbjct: 2485 VKASVIESVPRQDKAPKTVETTTRVVVRNVSTQAVLASTTMRLTDMRKPGLFVQDYYYTV 2544

Query: 918  DG-LAAIIPCPKENIYIFSVQDD 939
            +  LA I   P++++ IF +Q +
Sbjct: 2545 ERLLAGIFGVPRDHVVIFGIQQN 2567



 Score =  211 bits (516), Expect = 5e-54
 Identities = 231/881 (26%), Positives = 376/881 (42%), Gaps = 116/881 (13%)

Query: 11   INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I+V+D ND+ P F  + +    + + + +G+ VL+L A D D  +N EV + I       
Sbjct: 995  ISVIDVNDNVPRFTGITRIYKRINKNSLNGSPVLSLNALDLDYERNGEVGFQIV------ 1048

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P D               F I+     + T  +L++E    Y   V A D   P  + 
Sbjct: 1049 --PRDGP-------------FGINPVDEMIETTGNLNKES---YEFDVYAFDYGIPRLNS 1090

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             +    +HV  +             Y     E  +     +I  +KA      + + I Y
Sbjct: 1091 TTIPMVVHVAEVPPIFEVLDNDHNMYRFETAE--TSHGGELIGTVKAVSY---SKALIAY 1145

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
             I  GN +  F I +L+G++     ++YE     Y L + A +           ++I+++
Sbjct: 1146 EITSGNVRNSFKIGTLTGEIRHNNFMNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLK 1205

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-----AELTYTMTDKDYTG 303
            ++NDN PRF  SLF  +V+E+VP+G SI++V A D D   +      ELTY++ + D   
Sbjct: 1206 NINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTYSIDNTDM-- 1263

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                   I P +G +  +  LD E  +   L+V   D G  P    +             
Sbjct: 1264 -----FAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLLPVNDNS 1318

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
              F    Y  +++E    G  +  +TATD D D  + Y I G +  G + I   +G   +
Sbjct: 1319 PVFAQSNYAFQISETAEVGNELAFVTATDRDGD-PITYTIEGDS--GPYIIDPSSGIITL 1375

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA----SVF 479
            +   P++  +   Y   V ATD G  + T  V ++I D NN+ P F N   ++     + 
Sbjct: 1376 SREAPVNVWE---YNFKVKATD-GIFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIA 1431

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E+ P G  ++ V ATD D G+N ++ Y L        +   D  F I+  TG I T   L
Sbjct: 1432 ENLPSGQVLMQVQATDEDRGLNGEVEYEL-------VIGFTD--FSIDNTTGVIKTRYPL 1482

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVE-----ISVVDVNDNEPVFKQQLYTANIMEDA 594
            DRE  S   + V A+DGG        ++      +SVVD NDN P+F    Y +++ + A
Sbjct: 1483 DRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKA 1542

Query: 595  LVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRES---- 649
             VG S+ +V A D D G N ++ Y  ++P D+    F I+  +G++     L   +    
Sbjct: 1543 PVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDK----FAIEKTTGIVTVKTDLSSFTGFVT 1598

Query: 650  --VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
              V + +   + +  G   +    +V I +  +   PP+FE       + EN+ +GTTIG
Sbjct: 1599 LQVQSSNPVPITVSVGEDDRDRQTLVVIDVTTV--EPPMFERHLYNISVRENAAVGTTIG 1656

Query: 708  EIRA---------HDP-DEGPNAVVHYSIK---GG-----------------DDSNSFSL 737
            +IRA         + P  E PNA     I+   G                   D   F++
Sbjct: 1657 QIRAVSQNNRPIMYQPLHENPNAKEEIGIEIDTGSIVTSSKLDYESVNNYELQDYQKFTI 1716

Query: 738  ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
            +T++G+ +  +V   D + ES      +   A +PP    V V+I V D ND  P   D 
Sbjct: 1717 DTQRGTIRNAVV--FDREEESRYSLTAIATDAGTPPFSTQVFVKIDVLDANDQPPSFPDK 1774

Query: 798  QIIFNNYKDCFPVG-PFGRVPAYDAD-VTDKLQYRILSGNN 836
             +  +  +D  P+G    +    D+D V D   +  +SG N
Sbjct: 1775 NLQASVREDA-PIGSSVYKAVILDSDMVFDTSMHFFISGGN 1814



 Score =  209 bits (511), Expect = 2e-53
 Identities = 202/686 (29%), Positives = 321/686 (46%), Gaps = 71/686 (10%)

Query: 200  FSIDSLSGDVSLVKTLDYEQVRSYRLVIR-AQDGGSPSRSNTTQLLINIRDVNDNAPRF- 257
            FSID + GD+ + K LD+E+  SY L +R A+  GS  R     ++I++ DVNDN PRF 
Sbjct: 950  FSIDEI-GDIRVAKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVPRFT 1008

Query: 258  -YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
              T +++  +++N   G  ++ + A D D   N E+ + +  +D       P  I+P   
Sbjct: 1009 GITRIYKR-INKNSLNGSPVLSLNALDLDYERNGEVGFQIVPRDG------PFGINPVDE 1061

Query: 317  WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP---GQYEV 373
             + T+G L++E+   Y+  V A D G P  ++T                 +      Y  
Sbjct: 1062 MIETTGNLNKES---YEFDVYAFDYGIPRLNSTTIPMVVHVAEVPPIFEVLDNDHNMYRF 1118

Query: 374  ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK- 432
            E AE    G  + T+ A    +   + YEIT GN R  F I +  G   I     ++++ 
Sbjct: 1119 ETAETSHGGELIGTVKAVSYSK-ALIAYEITSGNVRNSFKIGTLTGE--IRHNNFMNYEI 1175

Query: 433  QERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
             E  Y LTV+A++    G      V I++ + N+  P F  + +T +V ED P+GT++L 
Sbjct: 1176 HENVYNLTVTASELIPRGHQTEIPVIIHLKNINDNYPRFTKSLFTTAVNEDVPVGTSILQ 1235

Query: 491  VSATDSDVGIN-----AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            V+ATD D   +      ++TYS+           +   F I+P TG I+    LD E  S
Sbjct: 1236 VTATDCDCSKSCLCAPGELTYSID----------NTDMFAISPDTGVISPAVSLDYEMSS 1285

Query: 546  GYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              +L V   D GG P++  +    I+++ VNDN PVF Q  Y   I E A VG  ++ V 
Sbjct: 1286 WVVLVVKVEDKGGSPNIMQSY-ANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVT 1344

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D      I Y +   + + G ++IDP+SG+I  ++     +V  ++ K  A DG  
Sbjct: 1345 ATDRD---GDPITYTI---EGDSGPYIIDPSSGIITLSREAP-VNVWEYNFKVKATDG-- 1395

Query: 665  PPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
               ++T  V + I D N+  P F    ES      I+EN P G  + +++A D D G N 
Sbjct: 1396 -IFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAENLPSGQVLMQVQATDEDRGLNG 1454

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-----PPLW 775
             V Y +  G     FS++   G  K    T   LD E   K+Y +V+RA         L+
Sbjct: 1455 EVEYELVIG--FTDFSIDNTTGVIK----TRYPLDRERTSKQY-IVVRAKDGGHRRNELF 1507

Query: 776  NDVR---VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRI 831
             ++    + + V D NDN P+    + + + Y+   PVG    RV A D D     +   
Sbjct: 1508 RNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKA-PVGHSLVRVKAIDLDTGSNAKVEY 1566

Query: 832  LSGNNANLILLNETTGSMTLSPQLNT 857
                 ++   + +TTG +T+   L++
Sbjct: 1567 TFVEPSDKFAIEKTTGIVTVKTDLSS 1592



 Score =  187 bits (455), Expect = 1e-46
 Identities = 229/882 (25%), Positives = 387/882 (43%), Gaps = 101/882 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +++ D N+H+P      Y A+V     + T ++T+ A+D D  +    +   + V+    
Sbjct: 94  LSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLD-KEEGNQQVLFQFVS---- 148

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              DA           Q+ F+ID  +G + +   L       Y + VKATD  SP    +
Sbjct: 149 ---DADSSG-------QNRFQIDSSTGTITSTNLLAANN--EYKLTVKATDTGSPP---M 193

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S  ++ V++I       +F+E  Y  ++ E + V  N V+ ++ AT       +AI Y+
Sbjct: 194 ESQVSVTVSVITPITTPVKFAEANYAKTIQESL-VIGNSVL-QVTATGP-----AAITYS 246

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRD 249
           I+GGN    F ID  +G +++ K LDYE ++SY L +RA  +  +P  +    + I + D
Sbjct: 247 IVGGNKNDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTD 306

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           VNDN+P F   L+    +         V V +Y  ++ V     +      Y    +  +
Sbjct: 307 VNDNSPVFL--LYSNPTT---------VTVNSYTPEQTV----VFKARRFTYYVIYEKAL 351

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +D  S    T    DR   A+Y + + ATDGG     +T T              F   
Sbjct: 352 AVDADSESFGTVRYSDR---AEYTVALVATDGGG---KSTTTSLVIKVFNINEPPKFPQP 405

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
           +YE  + E++  GT +  +TAT AD +  L Y IT GN    F +   N +G+I++A+ L
Sbjct: 406 KYEFSVPENKQVGTEIGAITATYADPNTLLKYSITRGNIDDTFCV---NSKGVISLAKAL 462

Query: 430 DFKQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           D   E +   T+ A  S G S+ T +VQI + D N+  P+ E   Y   V ED   GT V
Sbjct: 463 D--SETKASFTLDAMVSHGTSNHTTVVQITVNDINDNWPIMEPV-YNVEVREDQ--GTIV 517

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           +          ++      ++ +  +  VA  D     NP    + TNK +      G  
Sbjct: 518 MASFVIFCIAAVHKHYR-RIARKTCHVKVARLD-----NPL--PVLTNKAISSYLAPGTE 569

Query: 549 L---TVTARDGGVP-----SLSDTTDV-EISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           L     T  DGGV      ++  T D+   S+  VN +  V    LY A++  +  V   
Sbjct: 570 LVKVVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVI--TLYLASVPYEFPVNFH 627

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V QV ATDAD G N  + Y +     E+G F I+  +G++   + L   +   H L   A
Sbjct: 628 VFQVIATDADSGSNAELTYAI-TGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKA 686

Query: 660 IDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            D G P +  +ST+IV + + D+    P F    L   + E    G  +  ++       
Sbjct: 687 TDNGVPRRIGTSTIIVFVILADL---LPKFPVSPLIVNVKEGVLPGGRVTTVKMTS---- 739

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
            + ++ Y I  G+D   F +++  G    +L+ + +LDYE  R  + + I+        D
Sbjct: 740 -SRLMTYRILEGNDEGYFRMDSLSG----DLLALKELDYEDVR-TFTMRIKGQDTDGNAD 793

Query: 778 -VRVEILVTDVNDNAPVMK---DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRIL 832
            V + + + DVND +PV       +++    +     G P  ++  YD D  D+L +  L
Sbjct: 794 VVTLVVNLEDVNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFE-L 852

Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
           S     +  +++  G +  +  +N ++ +  +  V+V D  +
Sbjct: 853 SDEGERIFTIDD-EGQLIPTRSVN-DITEPLSFTVTVRDSAS 892



 Score =  163 bits (395), Expect = 2e-39
 Identities = 179/678 (26%), Positives = 293/678 (43%), Gaps = 70/678 (10%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID   G +     LD EK   YT+ V+  +     S R+     + +++ID NDN P+
Sbjct: 950  FSID-EIGDIRVAKPLDFEKQVSYTLTVREAESIGS-SPRVFDRVVV-ISVIDVNDNVPR 1006

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            F+  T         S+  +PV++ + A D D   N  + + I+  +    F I+ +   +
Sbjct: 1007 FTGITRIYKRINKNSLNGSPVLS-LNALDLDYERNGEVGFQIVPRDG--PFGINPVDEMI 1063

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIRDVNDNAPRFYT-----SLFQ 263
                 L+ E   SY   + A D G P  ++TT  +++++ +V    P F       ++++
Sbjct: 1064 ETTGNLNKE---SYEFDVYAFDYGIPRLNSTTIPMVVHVAEV---PPIFEVLDNDHNMYR 1117

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
               +E    G  I  V+A    +   A + Y +T    +GNV     I   +G +  +  
Sbjct: 1118 FETAETSHGGELIGTVKAVSYSK---ALIAYEIT----SGNVRNSFKIGTLTGEIRHNNF 1170

Query: 324  LDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            ++ E     Y L VTA++                         F    +   + ED P G
Sbjct: 1171 MNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLKNINDNYPRFTKSLFTTAVNEDVPVG 1230

Query: 383  TPVVTLTATDAD-------EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
            T ++ +TATD D           L Y I   NT   F+I+     G+I+ A  LD++   
Sbjct: 1231 TSILQVTATDCDCSKSCLCAPGELTYSI--DNT-DMFAISPDT--GVISPAVSLDYEMSS 1285

Query: 436  RYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
              VL V   D GG  +      NIT    N+ +PVF  + Y   + E A +G  +  V+A
Sbjct: 1286 WVVLVVKVEDKGGSPNIMQSYANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVTA 1345

Query: 494  TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            TD D      ITY++  +            ++I+P +G IT ++         Y   V A
Sbjct: 1346 TDRD---GDPITYTIEGD---------SGPYIIDPSSGIITLSREAPVNVWE-YNFKVKA 1392

Query: 554  RDGGVPSLSDTTDVEISVVDVNDNEPVF----KQQLYTANIMEDALVGTSVSQVGATDAD 609
             DG     + TTDV + ++D N+++P F    +       I E+   G  + QV ATD D
Sbjct: 1393 TDG---IFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAENLPSGQVLMQVQATDED 1449

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS- 668
             GLNG + YEL     +   F ID  +GVI+T   LDRE  +   +   A DGG      
Sbjct: 1450 RGLNGEVEYELVIGFTD---FSIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNEL 1506

Query: 669  ----STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
                +  ++ + + D ND+ P+F        + + +P+G ++  ++A D D G NA V Y
Sbjct: 1507 FRNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEY 1566

Query: 725  SIKGGDDSNSFSLETRQG 742
            +    + S+ F++E   G
Sbjct: 1567 TFV--EPSDKFAIEKTTG 1582



 Score =  161 bits (391), Expect = 7e-39
 Identities = 220/860 (25%), Positives = 361/860 (41%), Gaps = 91/860 (10%)

Query: 36   ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGR 95
            AS+G   L L +   +   N  V    +++  D  +  +A             +F+I+  
Sbjct: 606  ASTGVITLYLASVPYEFPVNFHV---FQVIATDADSGSNAELTYAITGGNEDGIFKINSE 662

Query: 96   SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
            +G +     L      ++ + +KATD   P   R   T+TI V +I   D  P+F     
Sbjct: 663  NGLVSLARPLASSAKIKHKLSLKATDNGVP---RRIGTSTIIVFVI-LADLLPKFPVSPL 718

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215
             V+V E        V+   + T   + ++  + Y I+ GN +  F +DSLSGD+  +K L
Sbjct: 719  IVNVKEG-------VLPGGRVTTVKMTSSRLMTYRILEGNDEGYFRMDSLSGDLLALKEL 771

Query: 216  DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE---SVSENVPI 272
            DYE VR++ + I+ QD  +   ++   L++N+ DVND +P F   +  E    V E   +
Sbjct: 772  DYEDVRTFTMRIKGQD--TDGNADVVTLVVNLEDVNDCSPVFAGEVGGEVMLRVEEPFLV 829

Query: 273  -GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
             G  +V++  YD D G    LT+ ++D+      +   TID     + T    D      
Sbjct: 830  AGVPVVKLDVYDKDAG--DRLTFELSDEG-----ERIFTIDDEGQLIPTRSVNDITEPLS 882

Query: 332  YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
            +   VT  D   PP   ++                +P   E  + ED   G  V  +   
Sbjct: 883  F--TVTVRDSASPPHVTSSRVTLNFEKLGEA----LP--VESRVREDAYIGMIVTFVPKV 934

Query: 392  DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD 451
                  ++ Y          FSI   +  G I VA+PLDF+++  Y LTV   +S G S 
Sbjct: 935  FPKSVFKITYP-----KDPAFSI---DEIGDIRVAKPLDFEKQVSYTLTVREAESIGSSP 986

Query: 452  TA---MVQINITDANNYAPVFEN-APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
                 +V I++ D N+  P F         + +++  G+ VL ++A D D   N ++ + 
Sbjct: 987  RVFDRVVVISVIDVNDNVPRFTGITRIYKRINKNSLNGSPVLSLNALDLDYERNGEVGFQ 1046

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
                     +   D  F INP    I T   L++E+   Y   V A D G+P L+ TT  
Sbjct: 1047 ---------IVPRDGPFGINPVDEMIETTGNLNKES---YEFDVYAFDYGIPRLNSTTIP 1094

Query: 568  EISVVDVNDNEPVFK-----QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
               VV V +  P+F+       +Y     E +  G  +  V A      L   I YE+  
Sbjct: 1095 --MVVHVAEVPPIFEVLDNDHNMYRFETAETSHGGELIGTVKAVSYSKAL---IAYEI-T 1148

Query: 623  KDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
                  SF I   +G IR N  ++ E     ++L   A +       + + V I +++IN
Sbjct: 1149 SGNVRNSFKIGTLTGEIRHNNFMNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLKNIN 1208

Query: 682  DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV-----VHYSIKGGDDSNSFS 736
            D+ P F     T  ++E+ P+GT+I ++ A D D   + +     + YSI   D+++ F+
Sbjct: 1209 DNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTYSI---DNTDMFA 1265

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELV---IRAASPPLWNDVRVEILVTDVNDNAPV 793
            +      D   +   V LDYE       +V    +  SP +       I +  VNDN+PV
Sbjct: 1266 I----SPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSY-ANITLLPVNDNSPV 1320

Query: 794  MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853
                   F   +          V A D D  D + Y I  G++   I ++ ++G +TLS 
Sbjct: 1321 FAQSNYAFQISETAEVGNELAFVTATDRD-GDPITYTI-EGDSGPYI-IDPSSGIITLSR 1377

Query: 854  QLNTNVPKLATMEVSVTDGV 873
            +   NV +    +V  TDG+
Sbjct: 1378 EAPVNVWEY-NFKVKATDGI 1396



 Score =  138 bits (333), Expect = 8e-32
 Identities = 137/488 (28%), Positives = 224/488 (45%), Gaps = 50/488 (10%)

Query: 209 VSLVKTL-DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           ++++K+L ++  V  +  +++  +   P+   T ++ ++I+DVN++AP    + +  +VS
Sbjct: 57  LTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVS 116

Query: 268 ENVPIGYSIVRVQAYDAD--EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
            + P    IV V A D D  EG    L   ++D D +G       ID  +G + ++  L 
Sbjct: 117 SDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSDADSSG--QNRFQIDSSTGTITSTNLLA 174

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
              +  Y+L V ATD G PP  +  +              F    Y   + E    G  V
Sbjct: 175 ANNE--YKLTVKATDTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQESLVIGNSV 232

Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
           + +TAT       + Y I GGN    F I    G+  I V +PLD++  + YVL V AT 
Sbjct: 233 LQVTATG---PAAITYSIVGGNKNDAFRIDRTTGQ--IAVNKPLDYEVLQSYVLNVRATC 287

Query: 446 SGGRSDTA---MVQINITDANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
                  A    V I +TD N+ +PVF   + P T +V    P  T V            
Sbjct: 288 ETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKA--------- 338

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
             + TY +   I  +A+A       ++  + +  T +  DR   + Y + + A DGG   
Sbjct: 339 -RRFTYYV---IYEKALA-------VDADSESFGTVRYSDR---AEYTVALVATDGG--G 382

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            S TT + I V ++N+  P F Q  Y  ++ E+  VGT +  + AT AD   N  + Y +
Sbjct: 383 KSTTTSLVIKVFNINE-PPKFPQPKYEFSVPENKQVGTEIGAITATYADP--NTLLKYSI 439

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
             +   + +F ++ + GVI   KALD E+ A+  L A+ +  GT   + T +V I + DI
Sbjct: 440 -TRGNIDDTFCVN-SKGVISLAKALDSETKASFTLDAM-VSHGT--SNHTTVVQITVNDI 494

Query: 681 NDSPPVFE 688
           ND+ P+ E
Sbjct: 495 NDNWPIME 502



 Score =  137 bits (332), Expect = 1e-31
 Identities = 180/719 (25%), Positives = 299/719 (41%), Gaps = 71/719 (9%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           D FRID  +G +     LD E +  Y + V+AT      + ++++   + + + D NDN 
Sbjct: 254 DAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRAT--CETYTPKIAAEVAVAITLTDVNDNS 311

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P F   +   +V  +    +  V+ K +             Y +I    +   ++D+   
Sbjct: 312 PVFLLYSNPTTVTVNSYTPEQTVVFKAR----------RFTYYVI---YEKALAVDA--- 355

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           D     T+ Y     Y + + A DGG   +S TT L+I + ++N+  P+F    ++ SV 
Sbjct: 356 DSESFGTVRYSDRAEYTVALVATDGG--GKSTTTSLVIKVFNINE-PPKFPQPKYEFSVP 412

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN  +G  I  + A  AD   N  L Y++T     GN+D    ++ + G +  +  LD E
Sbjct: 413 ENKQVGTEIGAITATYADP--NTLLKYSIT----RGNIDDTFCVNSK-GVISLAKALDSE 465

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           T+A + L    + G     S   T               M   Y VE+ ED+  GT V+ 
Sbjct: 466 TKASFTLDAMVSHG----TSNHTTVVQITVNDINDNWPIMEPVYNVEVREDQ--GTIVMA 519

Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-S 446
                       HY      T         N   ++T      +      ++ V ATD  
Sbjct: 520 SFVIFCIAAVHKHYRRIARKTCHVKVARLDNPLPVLTNKAISSYLAPGTELVKVVATDLD 579

Query: 447 GGRSDTAMVQINITDANNYAPVFE-NAP------YTASVFEDAPIGTTVLVVSATDSDVG 499
           GG   T    I  T     + +F  NA       Y ASV  + P+   V  V ATD+D G
Sbjct: 580 GGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLYLASVPYEFPVNFHVFQVIATDADSG 639

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            NA++TY+++    NE     D  F IN + G ++  + L       + L++ A D GVP
Sbjct: 640 SNAELTYAITG--GNE-----DGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVP 692

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
               T+ + + V+ + D  P F       N+ E  L G  V+ V  T + + +  RI   
Sbjct: 693 RRIGTSTIIVFVI-LADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSSRL-MTYRI--- 747

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
           L+  D  EG F +D  SG +   K LD E V T  ++    D  T   +  V + + +ED
Sbjct: 748 LEGND--EGYFRMDSLSGDLLALKELDYEDVRTFTMRIKGQD--TDGNADVVTLVVNLED 803

Query: 680 INDSPPVFESDC---LTFYISENSPI-GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
           +ND  PVF  +    +   + E   + G  + ++  +D D G       S +G      F
Sbjct: 804 VNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFELSDEG---ERIF 860

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPV 793
           +++     D+ +L+    ++  +    + + +R +ASPP     RV +    + +  PV
Sbjct: 861 TID-----DEGQLIPTRSVNDITEPLSFTVTVRDSASPPHVTSSRVTLNFEKLGEALPV 914



 Score =  126 bits (303), Expect = 3e-28
 Identities = 175/693 (25%), Positives = 280/693 (40%), Gaps = 74/693 (10%)

Query: 52   IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111
            + +N +V   I  +TA   +P +           + D F ++ +    L +A LD E  A
Sbjct: 411  VPENKQVGTEIGAITATYADP-NTLLKYSITRGNIDDTFCVNSKGVISLAKA-LDSETKA 468

Query: 112  RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS--VTDNP 169
             +T+    +   S      + T  + + + D NDN+P   E  Y V V ED    V  + 
Sbjct: 469  SFTLDAMVSHGTS------NHTTVVQITVNDINDNWP-IMEPVYNVEVREDQGTIVMASF 521

Query: 170  VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLV- 226
            VI  I A            Y  I   T     +  L   + ++  K +         LV 
Sbjct: 522  VIFCIAAVHK--------HYRRIARKT-CHVKVARLDNPLPVLTNKAISSYLAPGTELVK 572

Query: 227  IRAQDGGSPSRSNTTQLLINIRDVND------NAPRFYTSLFQESVSENVPIGYSIVRVQ 280
            + A D         T  +I  +D+        NA     +L+  SV    P+ + + +V 
Sbjct: 573  VVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLYLASVPYEFPVNFHVFQVI 632

Query: 281  AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
            A DAD G NAELTY +T     GN D    I+  +G V  +  L    + K++L + ATD
Sbjct: 633  ATDADSGSNAELTYAITG----GNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATD 688

Query: 341  GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400
             G P R  T+T              F      V + E   PG  V T+  T +     + 
Sbjct: 689  NGVPRRIGTST-IIVFVILADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSS---RLMT 744

Query: 401  YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
            Y I  GN  G F + S +G   +   + LD++  R + + +   D+ G +D   + +N+ 
Sbjct: 745  YRILEGNDEGYFRMDSLSGD--LLALKELDYEDVRTFTMRIKGQDTDGNADVVTLVVNLE 802

Query: 461  DANNYAPVFENAPYTASVFE-DAPI---GTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
            D N+ +PVF        +   + P    G  V+ +   D D G   ++T+ LS E     
Sbjct: 803  DVNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAG--DRLTFELSDE----- 855

Query: 517  VAHHDQQFVINPQTGAITTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
                ++ F I+ +   I T  + D  E +S    TVT RD   P    ++ V ++   + 
Sbjct: 856  ---GERIFTIDDEGQLIPTRSVNDITEPLS---FTVTVRDSASPPHVTSSRVTLNFEKLG 909

Query: 576  DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
            +  PV       + + EDA +G  V+ V           +I Y  DP      +F ID  
Sbjct: 910  EALPV------ESRVREDAYIGMIVTFVPKVFPKSVF--KITYPKDP------AFSIDEI 955

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
             G IR  K LD E   ++ L     +  G+ P+    +V I + D+ND+ P F      +
Sbjct: 956  -GDIRVAKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVPRFTGITRIY 1014

Query: 695  -YISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
              I++NS  G+ +  + A D D   N  V + I
Sbjct: 1015 KRINKNSLNGSPVLSLNALDLDYERNGEVGFQI 1047



 Score =  121 bits (291), Expect = 1e-26
 Identities = 115/442 (26%), Positives = 195/442 (44%), Gaps = 49/442 (11%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            +  I +L  ND+SPVF    Y   + E A  G  +  + ATD+D      + YTIE    
Sbjct: 1306 YANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVTATDRD---GDPITYTIE---G 1359

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            D+  P                 + ID  SG ++T +      V  Y   VKATD      
Sbjct: 1360 DS-GP-----------------YIIDPSSG-IITLSREAPVNVWEYNFKVKATDGI---- 1396

Query: 128  DRLSSTATIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
               ++T  + ++IID N++ PQF+   E + TV    + ++    V+ +++ATD D G N
Sbjct: 1397 --FTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAE-NLPSGQVLMQVQATDEDRGLN 1453

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-----N 239
              + Y ++ G T   FSID+ +G +     LD E+     +V+RA+DGG          N
Sbjct: 1454 GEVEYELVIGFT--DFSIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNIN 1511

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               +++++ D NDN P F+   +  SV +  P+G+S+VRV+A D D G NA++ YT  + 
Sbjct: 1512 YCLIIVSVVDANDNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTFVEP 1571

Query: 300  DYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                 ++     +  ++     +G +  + Q+   + +T + G D     T         
Sbjct: 1572 SDKFAIEKTTGIVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDDRDRQTLV---VIDV 1628

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQ 417
                   F    Y + + E+   GT +  + A    ++NR + Y+    N   +  I  +
Sbjct: 1629 TTVEPPMFERHLYNISVRENAAVGTTIGQIRA--VSQNNRPIMYQPLHENPNAKEEIGIE 1686

Query: 418  NGRGLITVAQPLDFKQERRYVL 439
               G I  +  LD++    Y L
Sbjct: 1687 IDTGSIVTSSKLDYESVNNYEL 1708



 Score =  118 bits (285), Expect = 5e-26
 Identities = 124/446 (27%), Positives = 197/446 (44%), Gaps = 46/446 (10%)

Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSS 510
           TA V ++I D NN+AP    A Y A+V  D P  T ++ V+A+D D    N Q+ +   S
Sbjct: 89  TAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVS 148

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
           +  +        +F I+  TG IT+  LL     + Y LTV A D G P +     V +S
Sbjct: 149 DADSSG----QNRFQIDSSTGTITSTNLL--AANNEYKLTVKATDTGSPPMESQVSVTVS 202

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           V+        F +  Y   I E  ++G SV QV AT         I Y +   ++ + +F
Sbjct: 203 VITPITTPVKFAEANYAKTIQESLVIGNSVLQVTATGP-----AAITYSIVGGNKND-AF 256

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVF-- 687
            ID  +G I  NK LD E + ++ L   A  +  TP  ++ V V I + D+ND+ PVF  
Sbjct: 257 RIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLL 316

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
            S+  T  ++  +P  T + + R           V Y      D++S S  T + SD+AE
Sbjct: 317 YSNPTTVTVNSYTPEQTVVFKARRF------TYYVIYEKALAVDADSESFGTVRYSDRAE 370

Query: 748 -LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
             V +V  D         LVI+  +   PP +   + E     V +N  V  +       
Sbjct: 371 YTVALVATDGGGKSTTTSLVIKVFNINEPPKFPQPKYEF---SVPENKQVGTE------- 420

Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863
                     G + A  AD    L+Y I  GN  +   +N + G ++L+  L++      
Sbjct: 421 ---------IGAITATYADPNTLLKYSITRGNIDDTFCVN-SKGVISLAKALDSETKASF 470

Query: 864 TMEVSVTDGVNEIKAMMQLSVRLITE 889
           T++  V+ G +    ++Q++V  I +
Sbjct: 471 TLDAMVSHGTSNHTTVVQITVNDIND 496



 Score = 93.1 bits (221), Expect = 3e-18
 Identities = 85/320 (26%), Positives = 144/320 (45%), Gaps = 25/320 (7%)

Query: 485 GTTVLVVSA----TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           GTT+L  S+     D D     Q   SL  E+++  V  H +    + +        L +
Sbjct: 8   GTTILDGSSGFQFVDDDTNPE-QFECSLM-EVTSMFVLEHFRVERSDSECRLTVIKSLFE 65

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             +++ +   V   +   P++  T  V++S+ DVN++ P   Q  Y A +  D    T +
Sbjct: 66  HHSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPI 125

Query: 601 SQVGATDADVGL-NGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V A+D D    N ++ ++   D     +  F ID ++G I +   L   +   + L  
Sbjct: 126 VTVTASDLDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTGTITSTNLLAANN--EYKLTV 183

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D G+PP  S V V + +     +P  F        I E+  IG ++ ++ A  P   
Sbjct: 184 KATDTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQESLVIGNSVLQVTATGP--- 240

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA----SPP 773
             A + YSI GG+ +++F ++   G    ++     LDYE   + Y L +RA     +P 
Sbjct: 241 --AAITYSIVGGNKNDAFRIDRTTG----QIAVNKPLDYE-VLQSYVLNVRATCETYTPK 293

Query: 774 LWNDVRVEILVTDVNDNAPV 793
           +  +V V I +TDVNDN+PV
Sbjct: 294 IAAEVAVAITLTDVNDNSPV 313



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 59/260 (22%), Positives = 107/260 (41%), Gaps = 28/260 (10%)

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD--EGPNAVV 722
           P   +T  V + I+D+N+  P          +S ++P  T I  + A D D  EG   V+
Sbjct: 84  PNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVL 143

Query: 723 HYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777
              +   D S  N F +++  G       T+   +  +   +Y+L ++A    SPP+ + 
Sbjct: 144 FQFVSDADSSGQNRFQIDSSTG-------TITSTNLLAANNEYKLTVKATDTGSPPMESQ 196

Query: 778 VRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836
           V V + ++T +    PV           ++   +G    V    A     + Y I+ GN 
Sbjct: 197 VSVTVSVITPIT--TPVKFAEANYAKTIQESLVIG--NSVLQVTATGPAAITYSIVGGNK 252

Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM----- 891
            +   ++ TTG + ++  L+  V +   + V  T      K   +++V +   ++     
Sbjct: 253 NDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSP 312

Query: 892 --LL--NSITVRLNDMTAEQ 907
             LL  N  TV +N  T EQ
Sbjct: 313 VFLLYSNPTTVTVNSYTPEQ 332



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 1271 PSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNG--TLAGCPEKRSRCSSAPCYNGAEC 1328
            P+S + K+ DF GC+SD   +   +D +  V       + GCP     C    C+N   C
Sbjct: 3202 PNSTKAKS-DFEGCVSDHRYNGYHMDKDRTVDRYQWRVIKGCP-----CEPGGCFNNGTC 3255

Query: 1329 SDLWDTYICDCKEGHTGKDC 1348
                    C C+ G+TG  C
Sbjct: 3256 MANATIPTCKCQPGYTGLTC 3275


>SB_1988| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 3889

 Score =  288 bits (706), Expect = 5e-77
 Identities = 238/796 (29%), Positives = 374/796 (46%), Gaps = 62/796 (7%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            N    ND S V     Y   V +  +  +  LT+ ATD+ I +N  V   +  V+A  ++
Sbjct: 1423 NKFTVNDTSGVL----YTTHVLDRETKASYQLTITATDKGIVENMTVGSHVIKVSA--VD 1476

Query: 72   PEDAXXXXXXXXXXVQ-DVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDR 129
            P++              D+F I+  SG +   A +DRE   A Y++LV A D   P  + 
Sbjct: 1477 PDEGSNGDILYSLQTDYDIFAINQTSGVIRVVALVDREAHPAGYSLLVVARDHGYPTPN- 1535

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             ++TA +++ I D NDN P+F + TY+ SV ED +V     + +++ATD D G    I +
Sbjct: 1536 -AATARVNITISDINDNAPRFLKFTYSGSVREDSTVGTE--VVQVQATDDDDGLAGEIVF 1592

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            AI GG+ +  FSI + SG +++ ++LD E   +Y L + A D     +S + ++ I I D
Sbjct: 1593 AITGGDPEGLFSILNTSGKITVARSLDREMKATYELTVTATDRAGDPKSTSVEVDITITD 1652

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P F        +SE+   G  ++ V A D D GVN ++ Y        G      
Sbjct: 1653 ANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGDSPK--GK----F 1706

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFMP 368
             ++  +G V T G+LD E   +Y + + A D G+P   S T                F  
Sbjct: 1707 AVNAITGVVSTVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLVDANDNNPTFTK 1766

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y   ++E+   GT V+ + AT+ D  +D+++ Y I+ G+    F+I        +TV 
Sbjct: 1767 AAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDHFAINH------LTVT 1820

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
              +D   +R  V            DTA+    +T       + E+ P   S  +++  G 
Sbjct: 1821 IHVDDVNDRAPVFRFHNYQKEIPEDTAVGTSILT----VEAIDEDTP---SNTKNSLGGQ 1873

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMS 545
             VL V+ATD D+G NAQ+TYS++ +         D +F I P +G I T+ L LDRE   
Sbjct: 1874 LVLKVTATDRDLGTNAQLTYSMAGD---------DNRFTIGPSSGEIRTSSLRLDREAKP 1924

Query: 546  GYLLTVTARDGGVPSLSDTTD-----VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             Y+L VTA D G    +D+ D     V+ S+VD N  + VF     T  I     +    
Sbjct: 1925 VYVLHVTATDSGGRRATDSDDGANGDVDYSIVDGNVGD-VFTINNATGEIRSFKPLDREA 1983

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              +G  +      G+  Y L  +  + G F +DP +G+I+T + L+R+   +++L   A 
Sbjct: 1984 --IGVVEDS---EGKGVYRLTIRGSDHGDFTLDPNTGMIKTARNLERQQTFSYNLTIGAA 2038

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G P  S+T  V I + D+ND+ PVF     +  + ENSP+GT++ ++ A D D G NA
Sbjct: 2039 DHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNA 2098

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777
             V YS+  GD    F   T+      E+   +D +       Y L I A     P     
Sbjct: 2099 YVTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVND---FYNLTITATDGGVPISRTA 2155

Query: 778  VRVEIL-VTDVNDNAP 792
            + + ++ + D NDN P
Sbjct: 2156 IAIALVRILDRNDNEP 2171



 Score =  283 bits (695), Expect = 1e-75
 Identities = 179/509 (35%), Positives = 267/509 (52%), Gaps = 35/509 (6%)

Query: 227  IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
            ++A+D GSPS  + T + I++ D NDN P+F + ++  S  EN   GY ++RV A DADE
Sbjct: 2952 MKAKDKGSPSLESNTTIEISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIRVSATDADE 3011

Query: 287  GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDP 344
            G NA+L Y +              +   SG V  SG+LD E+  Q  Y L ++ TD G  
Sbjct: 3012 GTNAQLAYNI--------------VSGTSGIVRPSGRLDYESMVQKHYVLNLSVTDHGVT 3057

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402
              ++ A               F   +Y   + E+ P GT V  +TA D D   ++++ Y 
Sbjct: 3058 QFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYS 3117

Query: 403  ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINIT 460
            +TGG+  G FSI    G+  I + + ++ + +  Y +T++A+D G    S  A V +++ 
Sbjct: 3118 LTGGD--GVFSIEPSTGQ--IRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVL 3173

Query: 461  DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            D N+  PVF +  Y  ++ E   +GT    V A D+D+G N ++ Y        E  A +
Sbjct: 3174 DVNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMY--------EITAGN 3225

Query: 521  DQ-QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
            DQ  F ++P  G+I  ++ LDRET     LTV A+D G+P LSD   V I + DVNDN P
Sbjct: 3226 DQGLFTLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDNAP 3285

Query: 580  VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
            V + +  +A + E+A  G  V QV ATDADV  NG + Y +       G F I+  +GVI
Sbjct: 3286 VIRPRNMSAAVPENAAAGEFVVQVNATDADVERNGHVTYTI--MHGALGMFTINETTGVI 3343

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
            RT   L+RES   + L  +A D G  P      + + + D ND+ P+F +    F + EN
Sbjct: 3344 RTQGVLNRESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPIFLTTFGPFSVVEN 3403

Query: 700  SPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
             P+GTT+GE+ A D D G NA + Y+I G
Sbjct: 3404 MPVGTTVGEVSASDNDIGTNAAISYTISG 3432



 Score =  276 bits (677), Expect = 2e-73
 Identities = 241/876 (27%), Positives = 383/876 (43%), Gaps = 59/876 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D ND +PVF    Y+  + E  + GT++LT++A D+D   N +     +LV   T 
Sbjct: 1821 IHVDDVNDRAPVFRFHNYQKEIPEDTAVGTSILTVEAIDEDTPSNTKNSLGGQLVLKVTA 1880

Query: 71   NPEDAXXXXXXXXXXVQD--VFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQAS--P 125
               D             D   F I   SG + T +  LDRE    Y + V ATD      
Sbjct: 1881 TDRDLGTNAQLTYSMAGDDNRFTIGPSSGEIRTSSLRLDREAKPVYVLHVTATDSGGRRA 1940

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                  +   +  +I+D N     F+    T  +       D   I  ++ ++       
Sbjct: 1941 TDSDDGANGDVDYSIVDGNVG-DVFTINNATGEI-RSFKPLDREAIGVVEDSE-----GK 1993

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             +    I G+    F++D  +G +   + L+ +Q  SY L I A D G PS S TT++ I
Sbjct: 1994 GVYRLTIRGSDHGDFTLDPNTGMIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSI 2053

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + D+NDN P F  + +  +V EN P+G S++ V A DAD G NA +TY++T  D  G +
Sbjct: 2054 VVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHG-L 2112

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXX 364
               +T     G +  +G LDRE    Y L +TATDGG P  R+A A              
Sbjct: 2113 FRAVT-KSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNEP 2171

Query: 365  XFMPGQYEVELAEDEPPGTPV-VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
             F   +Y   + E+  PG PV +   +      +R H      N  G FS T    R   
Sbjct: 2172 KFSHARYTGSIQENSGPGVPVQMRQHSVFYQPSHRRH------NNPG-FSNTEPRSRAHN 2224

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
             +  P       R+    + T   G    A V I++ DAN+  P F  +   +++ E A 
Sbjct: 2225 KLTLP-------RHAADQAGT---GHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAAS 2274

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            IG +V  V+A D D G+N +I +S++S          + +F I    G +  +  LDRE 
Sbjct: 2275 IGQSVARVTANDPDSGLNGRIFFSINS--------GSEGKFEIGRSDGVVRVSGSLDREA 2326

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             + Y+L V+A DG          V +++ DVNDN P F +  +  ++ E   VG+ +   
Sbjct: 2327 KAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNA 2386

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             ATD D G N  I Y +         F I+  +G +   + LDRE+   +     A DGG
Sbjct: 2387 TATDPDQGSNAAITYSM-----SYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDGG 2441

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
                 S V V+++I D ND+ P F +      + + +P+GT +  + A D D G N  V 
Sbjct: 2442 --GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVT 2499

Query: 724  YSIKGGDDSNSFSLETRQGSDKA-ELVTMVDL---DYESPRKKYELVIRA---ASPPLWN 776
            Y+I+   D   F+++   G     ++++ + L    + S    +   + A    + P   
Sbjct: 2500 YAIRDSRDPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRAT 2559

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGN 835
            +V V I + D  D++PV      +    +D  P+G     V          + Y I  G+
Sbjct: 2560 NVTVVINIVDSGDDSPVFNTSSYVVKIDED-RPIGSSVVMVEVVKKRAGTIIMYSI--GS 2616

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            + N+  ++  TG +T + +L+        + V  TD
Sbjct: 2617 SQNVFSIDNLTGLVTTAAKLDRESRDDYVITVQATD 2652



 Score =  262 bits (642), Expect = 3e-69
 Identities = 175/513 (34%), Positives = 260/513 (50%), Gaps = 37/513 (7%)

Query: 117  VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
            +KA D+ SP    L S  TI +++ID NDN P+FS   Y  S  E+        + ++ A
Sbjct: 2952 MKAKDKGSP---SLESNTTIEISLIDTNDNVPKFSSPVYYASAPEN--AYGGYQVIRVSA 3006

Query: 177  TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGS 234
            TDAD G N+ + Y I+ G           SG V     LDYE +  + Y L +   D G 
Sbjct: 3007 TDADEGTNAQLAYNIVSGT----------SGIVRPSGRLDYESMVQKHYVLNLSVTDHGV 3056

Query: 235  PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
               ++   L I++ D NDN P+F  S +  +V EN+P+G  +  V A D D G+N+++ Y
Sbjct: 3057 TQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMY 3116

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            ++T  D         +I+P +G +     ++RE +  Y + +TA+D G P  S+ A    
Sbjct: 3117 SLTGGDGV------FSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHV 3170

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF 412
                       F    YE  ++E    GT   ++ A DAD   + R+ YEIT GN +G F
Sbjct: 3171 HVLDVNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEITAGNDQGLF 3230

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470
            ++      G I V++PLD +  +   LTV A D G    SD A V I +TD N+ APV  
Sbjct: 3231 TLDPV--LGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDNAPVIR 3288

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
                +A+V E+A  G  V+ V+ATD+DV  N  +TY+    I + A+      F IN  T
Sbjct: 3289 PRNMSAAVPENAAAGEFVVQVNATDADVERNGHVTYT----IMHGALG----MFTINETT 3340

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G I T  +L+RE+   Y L V ARD G     D   +++ V+D NDN P+F       ++
Sbjct: 3341 GVIRTQGVLNRESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPIFLTTFGPFSV 3400

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
            +E+  VGT+V +V A+D D+G N  I Y +  K
Sbjct: 3401 VENMPVGTTVGEVSASDNDIGTNAAISYTISGK 3433



 Score =  258 bits (631), Expect = 6e-68
 Identities = 221/713 (30%), Positives = 333/713 (46%), Gaps = 69/713 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND++P F    Y  SVRE ++ GT V+ ++ATD D G   E+ + I   T    
Sbjct: 1543 ITISDINDNAPRFLKFTYSGSVREDSTVGTEVVQVQATDDDDGLAGEIVFAI---TGG-- 1597

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +PE               +F I   SG +    SLDRE  A Y + V ATD+A    D  
Sbjct: 1598 DPE--------------GLFSILNTSGKITVARSLDREMKATYELTVTATDRA---GDPK 1640

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S++  + + I D NDN P F+    T+ + E  ++   PVI  + ATD D+G N  +RY 
Sbjct: 1641 STSVEVDITITDANDNKPVFTNIPATILLSES-TIPGTPVIT-VVATDQDIGVNGQVRY- 1697

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIRD 249
             +G + + +F++++++G VS V  LDYE V+ Y + I A D G P  ++TT  L I++ D
Sbjct: 1698 -VGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLVD 1756

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P F  + +   VSE    G +++ V A + D G ++++TY ++  D   +     
Sbjct: 1757 ANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDH----F 1812

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  +  ++     DR    ++              ++  T               + G
Sbjct: 1813 AINHLTVTIHVDDVNDRAPVFRFHNYQKEIPEDTAVGTSILTVEAIDEDTPSNTKNSLGG 1872

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            Q  +++           T T  D   + +L Y + G +   RF+I   +G  + T +  L
Sbjct: 1873 QLVLKV-----------TATDRDLGTNAQLTYSMAGDD--NRFTIGPSSGE-IRTSSLRL 1918

Query: 430  DFKQERRYVLTVSATDSGGRSDT-------AMVQINITDANNYAPVFENAPYTASVFEDA 482
            D + +  YVL V+ATDSGGR  T         V  +I D  N   VF     T  +    
Sbjct: 1919 DREAKPVYVLHVTATDSGGRRATDSDDGANGDVDYSIVD-GNVGDVFTINNATGEIRSFK 1977

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P+    + V       G+     Y L+   S+    H D  F ++P TG I T + L+R+
Sbjct: 1978 PLDREAIGVVEDSEGKGV-----YRLTIRGSD----HGD--FTLDPNTGMIKTARNLERQ 2026

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                Y LT+ A D G+PS S TT V I V D+NDN PVF    Y+  + E++ VGTS+  
Sbjct: 2027 QTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLD 2086

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSF--VIDPASGVIRTNKALDRESVATHDLKAVAI 660
            V ATDAD G N  + Y +   D   G F  V     G I     LDRE    ++L   A 
Sbjct: 2087 VTATDADSGQNAYVTYSVTAGD-SHGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITAT 2145

Query: 661  DGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
            DGG P  +++  I  ++I D ND+ P F     T  I ENS  G  + ++R H
Sbjct: 2146 DGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPV-QMRQH 2197



 Score =  254 bits (622), Expect = 8e-67
 Identities = 251/877 (28%), Positives = 386/877 (44%), Gaps = 91/877 (10%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +   I + D ND+ PVF        + E    GT V+T+ ATDQDIG N +V Y  +   
Sbjct: 1644 VEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGD--- 1700

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                +P+                F ++  +G + T   LD E V RYTV + A DQ  P 
Sbjct: 1701 ----SPKGK--------------FAVNAITGVVSTVGELDYEDVQRYTVYIVAIDQGEP- 1741

Query: 127  SDRLSSTATIHVNI--IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
              +L+ST T+H+NI  +D NDN P F++  YT  V E+ +   N ++  + AT+ D G +
Sbjct: 1742 --QLNST-TLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIM--VNATERDSGKD 1796

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            S I Y I  G+    F+I+ L+  + +    D   V  +    +      P  +     +
Sbjct: 1797 SKITYNISAGDPLDHFAINHLTVTIHVDDVNDRAPVFRFHNYQKE----IPEDTAVGTSI 1852

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + +  ++++ P         S ++N   G  +++V A D D G NA+LTY+M   D    
Sbjct: 1853 LTVEAIDEDTP---------SNTKNSLGGQLVLKVTATDRDLGTNAQLTYSMAGDDNR-- 1901

Query: 305  VDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                 TI P SG + TS  +LDRE +  Y L VTATD G   R AT +            
Sbjct: 1902 ----FTIGPSSGEIRTSSLRLDREAKPVYVLHVTATDSGG--RRATDSDDGANGDVDYSI 1955

Query: 364  XXFMPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLH--YEIT-GGNTRGRFSITSQNG 419
                 G  + +  A  E      +   A    ED+     Y +T  G+  G F++    G
Sbjct: 1956 VDGNVGDVFTINNATGEIRSFKPLDREAIGVVEDSEGKGVYRLTIRGSDHGDFTLDPNTG 2015

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
              +I  A+ L+ +Q   Y LT+ A D G    S T  V I + D N+  PVF    Y+ +
Sbjct: 2016 --MIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTT 2073

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            VFE++P+GT++L V+ATD+D G NA +TYS+++  S     H   + V     G I    
Sbjct: 2074 VFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDS-----HGLFRAVTKSNHGTIEVAG 2128

Query: 538  LLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
             LDRE    Y LT+TA DGGVP S +      + ++D NDNEP F    YT +I E++  
Sbjct: 2129 NLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGP 2188

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G  V               + Y+   +      F     S     ++A ++ ++  H   
Sbjct: 2189 GVPVQM---------RQHSVFYQPSHRRHNNPGF-----SNTEPRSRAHNKLTLPRH--- 2231

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
              A   GT  +S   +V I + D ND+ P F    +   ISE + IG ++  + A+DPD 
Sbjct: 2232 -AADQAGTGHESLAEVV-IHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDS 2289

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
            G N  + +SI  G +      E  +      +   +D + ++        I  +  P   
Sbjct: 2290 GLNGRIFFSINSGSEG---KFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREG 2346

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835
               V + + DVNDN P  K  +  FN +  +   VG    V A   D        I    
Sbjct: 2347 YGTVTVTLQDVNDNTP--KFTKPAFNVDVSEGVAVGSV-IVNATATDPDQGSNAAITYSM 2403

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            +     +N  TGS+T++  L+    +  +  V   DG
Sbjct: 2404 SYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDG 2440



 Score =  240 bits (588), Expect = 1e-62
 Identities = 161/508 (31%), Positives = 237/508 (46%), Gaps = 31/508 (6%)

Query: 229  AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
            A D       +  +++I++ D NDN PRF  S  Q ++SE   IG S+ RV A D D G+
Sbjct: 2232 AADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGL 2291

Query: 289  NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
            N  + +++      G  +    I    G V  SG LDRE +A Y L V+A DG   PR  
Sbjct: 2292 NGRIFFSINSGS-EGKFE----IGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREG 2346

Query: 349  TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
              T              F    + V+++E    G+ +V  TATD D+ +     IT   +
Sbjct: 2347 YGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNA--AITYSMS 2404

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
               F+I S  G   +T+ +PLD + ++ Y  TV A D GG      V + I D N+ +P 
Sbjct: 2405 YPGFAINSNTGS--VTITRPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQ 2462

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            F    Y   V +  P+GT VL V+A D DVG N  +TY++         +     F I+ 
Sbjct: 2463 FPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRD-------SRDPGLFTIDA 2515

Query: 529  QTGAITTNKLLDRETM--SGYL-------LTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
              G IT NK++ R  +  SG+L         V ARD G    +    V I++VD  D+ P
Sbjct: 2516 NNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGDDSP 2575

Query: 580  VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
            VF    Y   I ED  +G+SV  V       G    I Y +      +  F ID  +G++
Sbjct: 2576 VFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAGT--IIMYSI---GSSQNVFSIDNLTGLV 2630

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISE 698
             T   LDRES   + +   A D G  P+     V I + DIND+ P F+        ++E
Sbjct: 2631 TTAAKLDRESRDDYVITVQATDNGQTPRVGYTSVVIHVTDINDNAPKFQFPAPYKMTVNE 2690

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            ++ +GT +G ++A D D+G N +  Y+I
Sbjct: 2691 DAALGTGVGRVKAIDGDQGLNGMFEYAI 2718



 Score =  233 bits (571), Expect = 1e-60
 Identities = 223/768 (29%), Positives = 357/768 (46%), Gaps = 68/768 (8%)

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            V+D      T HV   +   +Y Q +       + E+++V  +  + K+ A D D G+N 
Sbjct: 1427 VNDTSGVLYTTHVLDRETKASY-QLTITATDKGIVENMTVGSH--VIKVSAVDPDEGSNG 1483

Query: 186  AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPS-RSNTTQ 242
             I Y++    T    F+I+  SG + +V  +D E     Y L++ A+D G P+  + T +
Sbjct: 1484 DILYSL---QTDYDIFAINQTSGVIRVVALVDREAHPAGYSLLVVARDHGYPTPNAATAR 1540

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            + I I D+NDNAPRF    +  SV E+  +G  +V+VQA D D+G+  E+ + +T  D  
Sbjct: 1541 VNITISDINDNAPRFLKFTYSGSVREDSTVGTEVVQVQATDDDDGLAGEIVFAITGGDPE 1600

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            G   +  T    SG +  +  LDRE +A Y+L VTATD    P+S +             
Sbjct: 1601 GLFSILNT----SGKITVARSLDREMKATYELTVTATDRAGDPKSTSVEVDITITDANDN 1656

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F      + L+E   PGTPV+T+ ATD D          G + +G+F++ +  G  +
Sbjct: 1657 KPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGDSPKGKFAVNAITG--V 1714

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            ++    LD++  +RY + + A D G     S T  + I++ DAN+  P F  A YTA V 
Sbjct: 1715 VSTVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAHVS 1774

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E+A  GT V++V+AT+ D G +++ITY++S+    + + H    F IN  T  I  + + 
Sbjct: 1775 EEATAGTNVIMVNATERDSGKDSKITYNISA---GDPLDH----FAINHLTVTIHVDDVN 1827

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            DR  +  +             + + T V  S++ V   E + +    T +  +++L G  
Sbjct: 1828 DRAPVFRF-------HNYQKEIPEDTAVGTSILTV---EAIDED---TPSNTKNSLGGQL 1874

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAV 658
            V +V ATD D+G N ++ Y +   D     F I P+SG IRT+   LDRE+   + L   
Sbjct: 1875 VLKVTATDRDLGTNAQLTYSMAGDDNR---FTIGPSSGEIRTSSLRLDREAKPVYVLHVT 1931

Query: 659  AIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT-TIGEIRAH 712
            A D G          +   V   I D N    VF  +  T  I    P+    IG +   
Sbjct: 1932 ATDSGGRRATDSDDGANGDVDYSIVDGNVGD-VFTINNATGEIRSFKPLDREAIGVV--- 1987

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771
            +  EG   V   +I+G D  + F+L+   G  K    T  +L+ +     Y L I AA  
Sbjct: 1988 EDSEG-KGVYRLTIRGSDHGD-FTLDPNTGMIK----TARNLERQQTFS-YNLTIGAADH 2040

Query: 772  --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK-- 826
              P      RV I+V D+NDN PV          +++  PVG     V A DAD      
Sbjct: 2041 GLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENS-PVGTSLLDVTATDADSGQNAY 2099

Query: 827  LQYRILSGNNANLI--LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            + Y + +G++  L   +     G++ ++  L+  V     + ++ TDG
Sbjct: 2100 VTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITATDG 2147



 Score =  233 bits (571), Expect = 1e-60
 Identities = 172/527 (32%), Positives = 253/527 (48%), Gaps = 40/527 (7%)

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
            T A     + A D G P   +  T              F    Y     E+   G  V+ 
Sbjct: 2944 TAASQLAKMKAKDKGSPSLESNTTIEISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIR 3003

Query: 388  LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATD 445
            ++ATDADE         G N +  ++I S    G++  +  LD++   ++ YVL +S TD
Sbjct: 3004 VSATDADE---------GTNAQLAYNIVSGTS-GIVRPSGRLDYESMVQKHYVLNLSVTD 3053

Query: 446  SGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
             G    T  A++ I++TD N+  P F  + Y+A+V E+ P+GT V +V+A D D GIN+Q
Sbjct: 3054 HGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQ 3113

Query: 504  ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
            I YSL+           D  F I P TG I   K ++RE    Y +T+TA D G P LS 
Sbjct: 3114 IMYSLTGG---------DGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSS 3164

Query: 564  TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
               V + V+DVNDN PVF  ++Y   + E   VGT    V A DAD+G NGR+ YE+   
Sbjct: 3165 DAKVHVHVLDVNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEI-TA 3223

Query: 624  DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
              ++G F +DP  G IR ++ LDRE+  T  L  +A D G P  S    V I + D+ND+
Sbjct: 3224 GNDQGLFTLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDN 3283

Query: 684  PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
             PV     ++  + EN+  G  + ++ A D D   N  V Y+I  G     F++    G 
Sbjct: 3284 APVIRPRNMSAAVPENAAAGEFVVQVNATDADVERNGHVTYTIMHG-ALGMFTINETTGV 3342

Query: 744  DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800
             + + V    L+ ES +  Y L++ A    + P  +   +++ V D NDN P+   F   
Sbjct: 3343 IRTQGV----LNRES-KDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPI---FLTT 3394

Query: 801  FNNYK--DCFPVG-PFGRVPAYDADV-TDKLQYRILSGNNANLILLN 843
            F  +   +  PVG   G V A D D+ T+      +SG     + LN
Sbjct: 3395 FGPFSVVENMPVGTTVGEVSASDNDIGTNAAISYTISGKGPMSLRLN 3441



 Score =  225 bits (549), Expect = 5e-58
 Identities = 168/516 (32%), Positives = 239/516 (46%), Gaps = 43/516 (8%)

Query: 119  ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
            A DQA    + L   A + ++++D NDN P+F   +   ++ E  S+  +  +A++ A D
Sbjct: 2232 AADQAGTGHESL---AEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQS--VARVTAND 2286

Query: 179  ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
             D G N  I ++I  G+ + +F I    G V +  +LD E    Y L + A DG    R 
Sbjct: 2287 PDSGLNGRIFFSINSGS-EGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPRE 2345

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
                + + ++DVNDN P+F    F   VSE V +G  IV   A D D+G NA +TY+M+ 
Sbjct: 2346 GYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMS- 2404

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
              Y G       I+  +G V  +  LDRET+  Y   V A DGG     +          
Sbjct: 2405 --YPG-----FAINSNTGSVTITRPLDRETKQAYSFTVHARDGGG--LESNVAVNVEIGD 2455

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS 416
                   F   QY+ ++ +  P GT V+ + A D D  N  H  Y I      G F+I +
Sbjct: 2456 ENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRDSRDPGLFTIDA 2515

Query: 417  QNGRGLITVAQPLD---------FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465
             N  GLITV + +                +V  V A D G   R+    V INI D+ + 
Sbjct: 2516 NN--GLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGDD 2573

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            +PVF  + Y   + ED PIG++V++V       G    I YS+ S             F 
Sbjct: 2574 SPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAG--TIIMYSIGSS---------QNVFS 2622

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQ 584
            I+  TG +TT   LDRE+   Y++TV A D G       T V I V D+NDN P F+   
Sbjct: 2623 IDNLTGLVTTAAKLDRESRDDYVITVQATDNGQTPRVGYTSVVIHVTDINDNAPKFQFPA 2682

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
             Y   + EDA +GT V +V A D D GLNG   Y +
Sbjct: 2683 PYKMTVNEDAALGTGVGRVKAIDGDQGLNGMFEYAI 2718



 Score =  210 bits (514), Expect = 9e-54
 Identities = 162/511 (31%), Positives = 240/511 (46%), Gaps = 51/511 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+VLD ND++P F     ++++ E AS G +V  + A D D G N  + ++I        
Sbjct: 2248 IHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN------- 2300

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +  F I    G +    SLDRE  A Y + V A D +   S R 
Sbjct: 2301 -------------SGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGS--YSPR- 2344

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                T+ V + D NDN P+F++  + V V E ++V    VI    ATD D G+N+AI Y+
Sbjct: 2345 EGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAV--GSVIVNATATDPDQGSNAAITYS 2402

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +    +   F+I+S +G V++ + LD E  ++Y   + A+DGG    SN   + + I D 
Sbjct: 2403 M----SYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDGGG-LESNVA-VNVEIGDE 2456

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN+P+F T  +Q  V +  P+G  ++ V A D D G N  +TY + D    G      T
Sbjct: 2457 NDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRDSRDPGL----FT 2512

Query: 311  IDPRSGWVYTSGQLDR---------ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            ID  +G +  +  + R              +   V A D G  PR+   T          
Sbjct: 2513 IDANNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGD 2572

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F    Y V++ ED P G+ VV +          + Y I  G+++  FSI   N  G
Sbjct: 2573 DSPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAGTIIMYSI--GSSQNVFSI--DNLTG 2628

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE-NAPYTASV 478
            L+T A  LD +    YV+TV ATD+G   R     V I++TD N+ AP F+  APY  +V
Sbjct: 2629 LVTTAAKLDRESRDDYVITVQATDNGQTPRVGYTSVVIHVTDINDNAPKFQFPAPYKMTV 2688

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
             EDA +GT V  V A D D G+N    Y+++
Sbjct: 2689 NEDAALGTGVGRVKAIDGDQGLNGMFEYAIT 2719



 Score =  199 bits (486), Expect = 2e-50
 Identities = 158/493 (32%), Positives = 225/493 (45%), Gaps = 49/493 (9%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
            F+P   +  ++E    G  V  +TA D D   + R+ + I  G+  G+F I   +G  ++
Sbjct: 2260 FIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGS-EGKFEIGRSDG--VV 2316

Query: 424  TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             V+  LD + +  YVL VSA D     R     V + + D N+  P F    +   V E 
Sbjct: 2317 RVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEG 2376

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              +G+ ++  +ATD D G NA ITYS+S              F IN  TG++T  + LDR
Sbjct: 2377 VAVGSVIVNATATDPDQGSNAAITYSMSYP-----------GFAINSNTGSVTITRPLDR 2425

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            ET   Y  TV ARDGG   L     V + + D NDN P F    Y  ++++   VGT V 
Sbjct: 2426 ETKQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVL 2483

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL------ 655
             V A D DVG NG + Y +    R+ G F ID  +G+I  NK + R  +           
Sbjct: 2484 AVNAEDRDVGNNGHVTYAIRDS-RDPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGS 2542

Query: 656  ---KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
               K  A D GT P+++ V V I I D  D  PVF +      I E+ PIG+++  +   
Sbjct: 2543 FVFKVEARDHGTSPRATNVTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEVV 2602

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771
                G   ++ YSI  G   N FS++   G     + T   LD ES R  Y + ++A   
Sbjct: 2603 KKRAG--TIIMYSI--GSSQNVFSIDNLTGL----VTTAAKLDRES-RDDYVITVQATDN 2653

Query: 772  --PPLWNDVRVEILVTDVNDNAPVMK---DFQIIFNNYKDCFPVGPFGRVPAYDAD--VT 824
               P      V I VTD+NDNAP  +    +++  N  +D       GRV A D D  + 
Sbjct: 2654 GQTPRVGYTSVVIHVTDINDNAPKFQFPAPYKMTVN--EDAALGTGVGRVKAIDGDQGLN 2711

Query: 825  DKLQYRILSGNNA 837
               +Y I   N A
Sbjct: 2712 GMFEYAITHANIA 2724



 Score =  193 bits (470), Expect = 2e-48
 Identities = 103/257 (40%), Positives = 152/257 (59%), Gaps = 12/257 (4%)

Query: 86   VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
            +   F ID  +G +     LDRE    YT+ VKATD   PV  R S+ A ++V ++D ND
Sbjct: 1214 ISHTFAIDPMTGDIRAVGLLDRETKLNYTLDVKATD-VDPVDPRWSA-AVVYVEVLDSND 1271

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
            N P F +++Y V + E    T    + K++ATD DVG+N  I Y+I+ GN    F IDS 
Sbjct: 1272 NAPVFKKQSYVVEMVEHSPTTFT--VVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSS 1329

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            SG +   + +D E+++ Y L ++AQDGGSP+   T Q+ INI+DVNDN P   +S +  S
Sbjct: 1330 SGVIKPAQDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTAS 1389

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
            V EN P G S++++  +D D   N ++ +T+ +  +        T++  SG +YT+  LD
Sbjct: 1390 VPENQPPGQSVLKISVFDPDHAGNGQVAFTVNNNKF--------TVNDTSGVLYTTHVLD 1441

Query: 326  RETQAKYQLLVTATDGG 342
            RET+A YQL +TATD G
Sbjct: 1442 RETKASYQLTITATDKG 1458



 Score =  185 bits (451), Expect = 4e-46
 Identities = 153/506 (30%), Positives = 233/506 (46%), Gaps = 45/506 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+++D ND+ P F    Y AS  E A  G  V+ + ATD D G NA++ Y I   T+  
Sbjct: 2969 EISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIRVSATDADEGTNAQLAYNIVSGTSGI 3028

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            + P                       SG L   + + +  V   +V      Q +  S  
Sbjct: 3029 VRP-----------------------SGRLDYESMVQKHYVLNLSVTDHGVTQFT--SFA 3063

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L + +    N  D+   + Q SE + TV   E++ V     +   +  D+ +  NS I Y
Sbjct: 3064 LLNISVTDFN--DNQPQFNQ-SEYSATVL--ENMPVGTKVTMVTARDEDSGI--NSQIMY 3116

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++ GG+    FSI+  +G + L K ++ E   +Y + I A D G+P  S+  ++ +++ D
Sbjct: 3117 SLTGGDG--VFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLD 3174

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDN P F + +++ ++SE V +G     VQA DAD G N  + Y +T     GN     
Sbjct: 3175 VNDNPPVFTSRVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEIT----AGNDQGLF 3230

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            T+DP  G +  S  LDRET     L V A D G P  S  A+                P 
Sbjct: 3231 TLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSDQASVVIYLTDVNDNAPVIRPR 3290

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427
                 + E+   G  VV + ATDAD +   H  Y I  G   G F+I      G+I    
Sbjct: 3291 NMSAAVPENAAAGEFVVQVNATDADVERNGHVTYTIMHG-ALGMFTINETT--GVIRTQG 3347

Query: 428  PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             L+ + +  Y L V A D G     D   + +++ D N+  P+F       SV E+ P+G
Sbjct: 3348 VLNRESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTPIFLTTFGPFSVVENMPVG 3407

Query: 486  TTVLVVSATDSDVGINAQITYSLSSE 511
            TTV  VSA+D+D+G NA I+Y++S +
Sbjct: 3408 TTVGEVSASDNDIGTNAAISYTISGK 3433



 Score =  165 bits (402), Expect = 3e-40
 Identities = 89/230 (38%), Positives = 141/230 (61%), Gaps = 9/230 (3%)

Query: 436  RYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
            +Y+LT++A +   S   S   +V++N+ D N+  P F+++ Y  S+ E +P GT+V+ V+
Sbjct: 3631 QYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISEASPPGTSVVKVT 3690

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            A D D G N+++ Y     I ++A + +   F IN +TG ++T   +D      + + V 
Sbjct: 3691 AIDKDEGTNSRVLY----RIRHDASSANSDVFSINAETGVLSTQVFIDEYEYRAFTVIVE 3746

Query: 553  ARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            A+D G P+ LS T  V +++VDVNDN+PVF  +LY+ +I E AL G+SV QV ATDAD G
Sbjct: 3747 AKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVAATDADTG 3806

Query: 612  LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            +N R+ Y +   D E+G F I+ ++G+I  N ALDRES+ +  L   A +
Sbjct: 3807 INSRLTYRIISGD-EQGHFAINASTGLISVNSALDRESIDSFRLTVGAFN 3855



 Score =  160 bits (389), Expect = 1e-38
 Identities = 115/372 (30%), Positives = 187/372 (50%), Gaps = 30/372 (8%)

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            T +  L  + A+D G PSL   T +EIS++D NDN P F   +Y A+  E+A  G  V +
Sbjct: 2944 TAASQLAKMKAKDKGSPSLESNTTIEISLIDTNDNVPKFSSPVYYASAPENAYGGYQVIR 3003

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATHDLKAVAI- 660
            V ATDAD G N ++ Y            ++   SG++R +  LD ES V  H +  +++ 
Sbjct: 3004 VSATDADEGTNAQLAYN-----------IVSGTSGIVRPSGRLDYESMVQKHYVLNLSVT 3052

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G    +S  +++I + D ND+ P F     +  + EN P+GT +  + A D D G N+
Sbjct: 3053 DHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINS 3112

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777
             + YS+ GGD    FS+E   G  + +      ++ E+ ++ Y + I A+   +P L +D
Sbjct: 3113 QIMYSLTGGD--GVFSIEPSTGQIRLQKA----INREA-KENYHVTITASDRGTPVLSSD 3165

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADV--TDKLQYRILSG 834
             +V + V DVNDN PV    ++      +   VG     V A DAD+    ++ Y I +G
Sbjct: 3166 AKVHVHVLDVNDNPPVFTS-RVYERTMSEGVAVGTIAYSVQAVDADIGSNGRMMYEITAG 3224

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLL 893
            N+  L  L+   GS+ +S  L+    K  T+ V   D G+ ++    Q SV +   ++  
Sbjct: 3225 NDQGLFTLDPVLGSIRVSRPLDRETNKTITLTVLAKDQGIPQLSD--QASVVIYLTDVND 3282

Query: 894  NSITVRLNDMTA 905
            N+  +R  +M+A
Sbjct: 3283 NAPVIRPRNMSA 3294



 Score =  151 bits (367), Expect = 6e-36
 Identities = 97/258 (37%), Positives = 137/258 (53%), Gaps = 11/258 (4%)

Query: 524  FVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFK 582
            F I+P TG I    LLDRET   Y L V A D   V        V + V+D NDN PVFK
Sbjct: 1218 FAIDPMTGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFK 1277

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
            +Q Y   ++E +    +V +V ATD DVG NGRI Y +      +G+FVID +SGVI+  
Sbjct: 1278 KQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSI-VSGNVDGAFVIDSSSGVIKPA 1336

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            + +DRE +  + L   A DGG+P   +TV V I I+D+ND+ PV  S   T  + EN P 
Sbjct: 1337 QDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPENQPP 1396

Query: 703  GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
            G ++ +I   DPD   N  V +++    ++N F++    G     L T   LD E+ +  
Sbjct: 1397 GQSVLKISVFDPDHAGNGQVAFTV----NNNKFTVNDTSG----VLYTTHVLDRET-KAS 1447

Query: 763  YELVIRAASPPLWNDVRV 780
            Y+L I A    +  ++ V
Sbjct: 1448 YQLTITATDKGIVENMTV 1465



 Score =  147 bits (356), Expect = 1e-34
 Identities = 91/250 (36%), Positives = 134/250 (53%), Gaps = 16/250 (6%)

Query: 429  LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            LD + +  Y L V ATD      R   A+V + + D+N+ APVF+   Y   + E +P  
Sbjct: 1233 LDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVVEMVEHSPTT 1292

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
             TV+ V ATD DVG N +I+YS+ S        + D  FVI+  +G I   + +DRE + 
Sbjct: 1293 FTVVKVEATDRDVGSNGRISYSIVS-------GNVDGAFVIDSSSGVIKPAQDIDREKIQ 1345

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             YLL V A+DGG P+L  T  V I++ DVNDN PV     YTA++ E+   G SV ++  
Sbjct: 1346 RYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPENQPPGQSVLKISV 1405

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             D D   NG++ + ++        F ++  SGV+ T   LDRE+ A++ L   A D G  
Sbjct: 1406 FDPDHAGNGQVAFTVN-----NNKFTVNDTSGVLYTTHVLDRETKASYQLTITATDKGI- 1459

Query: 666  PQSSTVIVHI 675
             ++ TV  H+
Sbjct: 1460 VENMTVGSHV 1469



 Score =  140 bits (339), Expect = 1e-32
 Identities = 95/254 (37%), Positives = 131/254 (51%), Gaps = 20/254 (7%)

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXFMP 368
            IDP +G +   G LDRET+  Y L V ATD  DP  PR + A               F  
Sbjct: 1220 IDPMTGDIRAVGLLDRETKLNYTLDVKATDV-DPVDPRWSAAVVYVEVLDSNDNAPVFKK 1278

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y VE+ E  P    VV + ATD D   + R+ Y I  GN  G F I S +G  +I  A
Sbjct: 1279 QSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSSSG--VIKPA 1336

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPI 484
            Q +D ++ +RY+L V A D G  +  A VQ  INI D N+  PV  ++ YTASV E+ P 
Sbjct: 1337 QDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPENQPP 1396

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G +VL +S  D D   N Q+ +++           ++ +F +N  +G + T  +LDRET 
Sbjct: 1397 GQSVLKISVFDPDHAGNGQVAFTV-----------NNNKFTVNDTSGVLYTTHVLDRETK 1445

Query: 545  SGYLLTVTARDGGV 558
            + Y LT+TA D G+
Sbjct: 1446 ASYQLTITATDKGI 1459



 Score =  140 bits (338), Expect = 2e-32
 Identities = 82/233 (35%), Positives = 128/233 (54%), Gaps = 20/233 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++NVLD ND  P F+   Y  S+ E +  GT+V+ + A D+D G N+ V Y I       
Sbjct: 3654 RVNVLDVNDDIPAFKSSSYNMSISEASPPGTSVVKVTAIDKDEGTNSRVLYRIR------ 3707

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                DA            DVF I+  +G L T+  +D  +   +TV+V+A D  SP +  
Sbjct: 3708 ---HDASSANS-------DVFSINAETGVLSTQVFIDEYEYRAFTVIVEAKDMGSPTA-- 3755

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSST  ++V I+D NDN P F+ K Y+ S+ E  S  +   + ++ ATDAD G NS + Y
Sbjct: 3756 LSSTVPVYVTIVDVNDNQPVFANKLYSTSISE--SALNGSSVIQVAATDADTGINSRLTY 3813

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
             II G+ Q  F+I++ +G +S+   LD E + S+RL + A +  + + +NT++
Sbjct: 3814 RIISGDEQGHFAINASTGLISVNSALDRESIDSFRLTVGAFNDEALAFNNTSR 3866



 Score =  128 bits (309), Expect = 6e-29
 Identities = 77/238 (32%), Positives = 132/238 (55%), Gaps = 14/238 (5%)

Query: 106  DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165
            +RE++++Y + + A +  +  S  LSS   + VN++D ND+ P F   +Y +S+ E  + 
Sbjct: 3625 NRERISQYLLTITAANLDT--SPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISE--AS 3680

Query: 166  TDNPVIAKIKATDADVGANSAIRYAI----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221
                 + K+ A D D G NS + Y I       N+ + FSI++ +G +S    +D  + R
Sbjct: 3681 PPGTSVVKVTAIDKDEGTNSRVLYRIRHDASSANSDV-FSINAETGVLSTQVFIDEYEYR 3739

Query: 222  SYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
            ++ +++ A+D GSP+  S+T  + + I DVNDN P F   L+  S+SE+   G S+++V 
Sbjct: 3740 AFTVIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVA 3799

Query: 281  AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
            A DAD G+N+ LTY +   D  G+      I+  +G +  +  LDRE+   ++L V A
Sbjct: 3800 ATDADTGINSRLTYRIISGDEQGH----FAINASTGLISVNSALDRESIDSFRLTVGA 3853



 Score =  124 bits (299), Expect = 1e-27
 Identities = 104/339 (30%), Positives = 162/339 (47%), Gaps = 20/339 (5%)

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQL-YTAN---IMEDALVGTSVSQVGATDADVGLNGR 615
            +++DT+ V +    V D E     QL  TA    I+E+  VG+ V +V A D D G NG 
Sbjct: 1426 TVNDTSGV-LYTTHVLDRETKASYQLTITATDKGIVENMTVGSHVIKVSAVDPDEGSNGD 1484

Query: 616  IHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATHDLKAVAIDGGTP-PQSSTVIV 673
            I Y L     +   F I+  SGVIR    +DRE+  A + L  VA D G P P ++T  V
Sbjct: 1485 ILYSLQT---DYDIFAINQTSGVIRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARV 1541

Query: 674  HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            +I I DIND+ P F     +  + E+S +GT + +++A D D+G    + ++I GGD   
Sbjct: 1542 NITISDINDNAPRFLKFTYSGSVREDSTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEG 1601

Query: 734  SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790
             FS+    G    ++     LD E  +  YEL + A   A  P    V V+I +TD NDN
Sbjct: 1602 LFSILNTSG----KITVARSLDREM-KATYELTVTATDRAGDPKSTSVEVDITITDANDN 1656

Query: 791  APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850
             PV  +        +   P  P   V A D D+    Q R +  +      +N  TG ++
Sbjct: 1657 KPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGDSPKGKFAVNAITGVVS 1716

Query: 851  LSPQLN-TNVPKLATMEVSVTDGVNEIKA-MMQLSVRLI 887
               +L+  +V +     V++  G  ++ +  + L++ L+
Sbjct: 1717 TVGELDYEDVQRYTVYIVAIDQGEPQLNSTTLHLNISLV 1755



 Score =  122 bits (295), Expect = 3e-27
 Identities = 75/209 (35%), Positives = 113/209 (54%), Gaps = 4/209 (1%)

Query: 538  LLDRETMSGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            L +RE +S YLLT+TA +    P+LS    V ++V+DVND+ P FK   Y  +I E +  
Sbjct: 3623 LQNRERISQYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISEASPP 3682

Query: 597  GTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
            GTSV +V A D D G N R+ Y +  D        F I+  +GV+ T   +D        
Sbjct: 3683 GTSVVKVTAIDKDEGTNSRVLYRIRHDASSANSDVFSINAETGVLSTQVFIDEYEYRAFT 3742

Query: 655  LKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            +   A D G+P   SSTV V++ I D+ND+ PVF +   +  ISE++  G+++ ++ A D
Sbjct: 3743 VIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVAATD 3802

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
             D G N+ + Y I  GD+   F++    G
Sbjct: 3803 ADTGINSRLTYRIISGDEQGHFAINASTG 3831



 Score =  119 bits (287), Expect = 3e-26
 Identities = 84/264 (31%), Positives = 130/264 (49%), Gaps = 14/264 (5%)

Query: 317  WVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            + YT    +RE  ++Y L +TA +    P  S+                 F    Y + +
Sbjct: 3617 YFYTCFLQNRERISQYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSI 3676

Query: 376  AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFK 432
            +E  PPGT VV +TA D DE  ++R+ Y I    +     + S N   G+++    +D  
Sbjct: 3677 SEASPPGTSVVKVTAIDKDEGTNSRVLYRIRHDASSANSDVFSINAETGVLSTQVFIDEY 3736

Query: 433  QERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            + R + + V A D G     S T  V + I D N+  PVF N  Y+ S+ E A  G++V+
Sbjct: 3737 EYRAFTVIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVI 3796

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
             V+ATD+D GIN+++TY +   IS +   H    F IN  TG I+ N  LDRE++  + L
Sbjct: 3797 QVAATDADTGINSRLTYRI---ISGDEQGH----FAINASTGLISVNSALDRESIDSFRL 3849

Query: 550  TVTARDGGVPSLSDTTDVEISVVD 573
            TV A +    + ++T+  E   VD
Sbjct: 3850 TVGAFNDEALAFNNTSRREQRNVD 3873



 Score =  116 bits (279), Expect = 3e-25
 Identities = 74/249 (29%), Positives = 116/249 (46%), Gaps = 9/249 (3%)

Query: 200  FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFY 258
            F+ID ++GD+  V  LD E   +Y L ++A D      R +   + + + D NDNAP F 
Sbjct: 1218 FAIDPMTGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFK 1277

Query: 259  TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
               +   + E+ P  +++V+V+A D D G N  ++Y++     +GNVD    ID  SG +
Sbjct: 1278 KQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIV----SGNVDGAFVIDSSSGVI 1333

Query: 319  YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
              +  +DRE   +Y L V A DGG P   AT                     Y   + E+
Sbjct: 1334 KPAQDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASVPEN 1393

Query: 379  EPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
            +PPG  V+ ++  D D         T  N +   + TS    G++     LD + +  Y 
Sbjct: 1394 QPPGQSVLKISVFDPDHAGNGQVAFTVNNNKFTVNDTS----GVLYTTHVLDRETKASYQ 1449

Query: 439  LTVSATDSG 447
            LT++ATD G
Sbjct: 1450 LTITATDKG 1458



 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 65/199 (32%), Positives = 106/199 (53%), Gaps = 18/199 (9%)

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
           I+V    ++  I ATD+D G NSA+ Y I  GN    F++D+L+G +S    LD E    
Sbjct: 225 ITVVTYFMLTIILATDSDRGINSALHYMIDSGNFGNSFTLDALTGSLSTTGPLDREVRAE 284

Query: 223 YRLVIRAQD--G----GSPSRSNTT-----QLLINIRDVNDNAPRFYTSLFQESVSENVP 271
           Y L++   D  G    G P R +       ++ I I DVND+ P F  +++   + EN+ 
Sbjct: 285 YTLLVFVSDLQGNASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENIT 344

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP--ITIDPRSGWVYTSGQLDRETQ 329
           +G  +++    D D G N +++Y ++    +GN + P   +++P SG +  S + D +T 
Sbjct: 345 LGTVVLQPSCVDRDLGTNGQISYHIS----SGNSETPPRFSVNPSSGALSVSTEFDFDTG 400

Query: 330 AK-YQLLVTATDGGDPPRS 347
            K Y L++TATD G+P  S
Sbjct: 401 RKSYSLVLTATDKGEPALS 419



 Score = 95.1 bits (226), Expect = 7e-19
 Identities = 71/248 (28%), Positives = 119/248 (47%), Gaps = 13/248 (5%)

Query: 629  SFVIDPASGVIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
            +F IDP +G IR    LDRE+   +  D+KA  +D    P+ S  +V++++ D ND+ PV
Sbjct: 1217 TFAIDPMTGDIRAVGLLDRETKLNYTLDVKATDVDP-VDPRWSAAVVYVEVLDSNDNAPV 1275

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
            F+       + E+SP   T+ ++ A D D G N  + YSI  G+   +F +++  G  K 
Sbjct: 1276 FKKQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSSSGVIKP 1335

Query: 747  ELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
                  D+D E  ++ Y L ++A    SP L   V+V I + DVNDN PV+       + 
Sbjct: 1336 AQ----DIDREKIQR-YLLGVQAQDGGSPTLQATVQVTINIQDVNDNTPVLTSSTYTASV 1390

Query: 804  YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863
             ++  P     ++  +D D     Q      NN     +N+T+G +  +  L+       
Sbjct: 1391 PENQPPGQSVLKISVFDPDHAGNGQVAFTVNNNK--FTVNDTSGVLYTTHVLDRETKASY 1448

Query: 864  TMEVSVTD 871
             + ++ TD
Sbjct: 1449 QLTITATD 1456



 Score = 91.9 bits (218), Expect = 7e-18
 Identities = 58/149 (38%), Positives = 79/149 (53%), Gaps = 9/149 (6%)

Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
           DS    D     I + D N+ APVF     YT  V ++  +G +V  V ATD D GINA 
Sbjct: 40  DSDDDDDDDEDDIILDDVNDNAPVFSRPEGYTFEV-QEGGVGLSVGTVQATDRDSGINAA 98

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
             YSL S      VA + + F+I+ +TG I T+  LDRET     + V ARD G P LS 
Sbjct: 99  TLYSLKS------VADYSK-FIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSA 151

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIME 592
              + ++V D+ND+ P F Q+ Y+  + E
Sbjct: 152 EVGIIVNVTDINDHRPAFSQRQYSVTVQE 180



 Score = 90.2 bits (214), Expect = 2e-17
 Identities = 68/218 (31%), Positives = 112/218 (51%), Gaps = 9/218 (4%)

Query: 646  DRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            +RE ++ + L   A +  T P  SS V+V + + D+ND  P F+S      ISE SP GT
Sbjct: 3625 NRERISQYLLTITAANLDTSPALSSGVVVRVNVLDVNDDIPAFKSSSYNMSISEASPPGT 3684

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            ++ ++ A D DEG N+ V Y I+  D S++ S      ++   L T V +D E   + + 
Sbjct: 3685 SVVKVTAIDKDEGTNSRVLYRIR-HDASSANSDVFSINAETGVLSTQVFID-EYEYRAFT 3742

Query: 765  LVIRA---ASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
            +++ A    SP  L + V V + + DVNDN PV  +     +  +         +V A D
Sbjct: 3743 VIVEAKDMGSPTALSSTVPVYVTIVDVNDNQPVFANKLYSTSISESALNGSSVIQVAATD 3802

Query: 821  AD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            AD  +  +L YRI+SG+      +N +TG ++++  L+
Sbjct: 3803 ADTGINSRLTYRIISGDEQGHFAINASTGLISVNSALD 3840



 Score = 86.6 bits (205), Expect = 3e-16
 Identities = 63/191 (32%), Positives = 95/191 (49%), Gaps = 23/191 (12%)

Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
           + ATD+D   ++ LHY I  GN    F++ +  G   ++   PLD +    Y L V  +D
Sbjct: 236 ILATDSDRGINSALHYMIDSGNFGNSFTLDALTGS--LSTTGPLDREVRAEYTLLVFVSD 293

Query: 446 SGGRS-------DTAMVQ------INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             G +       D+A+V       I I+D N+  P F  A Y+  + E+  +GT VL  S
Sbjct: 294 LQGNASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPS 353

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTV 551
             D D+G N QI+Y +SS  S         +F +NP +GA++ +   D +T    Y L +
Sbjct: 354 CVDRDLGTNGQISYHISSGNSET-----PPRFSVNPSSGALSVSTEFDFDTGRKSYSLVL 408

Query: 552 TARDGGVPSLS 562
           TA D G P+LS
Sbjct: 409 TATDKGEPALS 419



 Score = 86.2 bits (204), Expect = 3e-16
 Identities = 62/193 (32%), Positives = 97/193 (50%), Gaps = 22/193 (11%)

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
           ++ ATDSD GIN+ + Y + S        +    F ++  TG+++T   LDRE  + Y L
Sbjct: 235 IILATDSDRGINSALHYMIDS-------GNFGNSFTLDALTGSLSTTGPLDREVRAEYTL 287

Query: 550 TVTARD--G----GVPSLSDTT------DVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            V   D  G    G+P L D+       +V I++ DVND+ P F Q +Y+  I E+  +G
Sbjct: 288 LVFVSDLQGNASLGIP-LRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENITLG 346

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRES-VATHDL 655
           T V Q    D D+G NG+I Y +   + E    F ++P+SG +  +   D ++   ++ L
Sbjct: 347 TVVLQPSCVDRDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSL 406

Query: 656 KAVAIDGGTPPQS 668
              A D G P  S
Sbjct: 407 VLTATDKGEPALS 419



 Score = 84.2 bits (199), Expect = 1e-15
 Identities = 49/126 (38%), Positives = 72/126 (57%), Gaps = 3/126 (2%)

Query: 563 DTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           D  + +I + DVNDN PVF + + YT  + E   VG SV  V ATD D G+N    Y L 
Sbjct: 46  DDDEDDIILDDVNDNAPVFSRPEGYTFEVQEGG-VGLSVGTVQATDRDSGINAATLYSLK 104

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
               +   F+ID  +GVI+T+ +LDRE+    +++ +A D G+P  S+ V + + + DIN
Sbjct: 105 SV-ADYSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDIN 163

Query: 682 DSPPVF 687
           D  P F
Sbjct: 164 DHRPAF 169



 Score = 82.6 bits (195), Expect = 4e-15
 Identities = 59/160 (36%), Positives = 85/160 (53%), Gaps = 13/160 (8%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATD---QAS---PVSDRLSSTATIHVNII-- 141
           F +D  +G+L T   LDRE  A YT+LV  +D    AS   P+ D       I V I   
Sbjct: 262 FTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQGNASLGIPLRDSAVVNVFIEVTITIS 321

Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN--TQMQ 199
           D ND+ P+FS+  Y+V + E+I++    V+ +    D D+G N  I Y I  GN  T  +
Sbjct: 322 DVNDSPPEFSQAMYSVRIPENITL--GTVVLQPSCVDRDLGTNGQISYHISSGNSETPPR 379

Query: 200 FSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRS 238
           FS++  SG +S+    D++  R SY LV+ A D G P+ S
Sbjct: 380 FSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPALS 419



 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 59/178 (33%), Positives = 83/178 (46%), Gaps = 18/178 (10%)

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID--G 662
           ATD+D G+N  +HY +D       SF +D  +G + T   LDRE  A + L     D  G
Sbjct: 238 ATDSDRGINSALHYMID-SGNFGNSFTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQG 296

Query: 663 ----GTPPQSSTVI-----VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
               G P + S V+     V I I D+NDSPP F     +  I EN  +GT + +    D
Sbjct: 297 NASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVD 356

Query: 714 PDEGPNAVVHYSIKGGDDSN--SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            D G N  + Y I  G+      FS+    G+    L    + D+++ RK Y LV+ A
Sbjct: 357 RDLGTNGQISYHISSGNSETPPRFSVNPSSGA----LSVSTEFDFDTGRKSYSLVLTA 410



 Score = 70.9 bits (166), Expect = 1e-11
 Identities = 54/186 (29%), Positives = 86/186 (46%), Gaps = 29/186 (15%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN++D  D SPVF    Y   + E    G++V+ ++   +  G    + Y+I        
Sbjct: 2565 INIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAG--TIIMYSI-------- 2614

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            Q+VF ID  +G + T A LDRE    Y + V+ATD     + R+
Sbjct: 2615 -------------GSSQNVFSIDNLTGLVTTAAKLDRESRDDYVITVQATDNGQ--TPRV 2659

Query: 131  SSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              T+ + +++ D NDN P+F     Y ++V+ED ++     + ++KA D D G N    Y
Sbjct: 2660 GYTSVV-IHVTDINDNAPKFQFPAPYKMTVNEDAALGTG--VGRVKAIDGDQGLNGMFEY 2716

Query: 190  AIIGGN 195
            AI   N
Sbjct: 2717 AITHAN 2722



 Score = 69.3 bits (162), Expect = 4e-11
 Identities = 54/148 (36%), Positives = 78/148 (52%), Gaps = 24/148 (16%)

Query: 15  DCNDHSPVFEMQQ-YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPE 73
           D ND++PVF   + Y   V+EG   G +V T++ATD+D G NA   Y+++ V AD     
Sbjct: 56  DVNDNAPVFSRPEGYTFEVQEGGV-GLSVGTVQATDRDSGINAATLYSLKSV-AD----- 108

Query: 74  DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133
                           F ID ++G + T  SLDRE   +  + V A D  SP   +LS+ 
Sbjct: 109 -------------YSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSP---QLSAE 152

Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDE 161
             I VN+ D ND+ P FS++ Y+V+V E
Sbjct: 153 VGIIVNVTDINDHRPAFSQRQYSVTVQE 180



 Score = 68.1 bits (159), Expect = 9e-11
 Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 7/132 (5%)

Query: 140 IIDD-NDNYPQFSE-KTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
           I+DD NDN P FS  + YT  V E  + ++    +  ++ATD D G N+A  Y++     
Sbjct: 53  ILDDVNDNAPVFSRPEGYTFEVQEGGVGLS----VGTVQATDRDSGINAATLYSLKSVAD 108

Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
             +F IDS +G +    +LD E      + + A+D GSP  S    +++N+ D+ND+ P 
Sbjct: 109 YSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPA 168

Query: 257 FYTSLFQESVSE 268
           F    +  +V E
Sbjct: 169 FSQRQYSVTVQE 180



 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 48/146 (32%), Positives = 65/146 (44%), Gaps = 7/146 (4%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTG 303
           I + DVNDNAP F          +   +G S+  VQA D D G+NA   Y++    DY+ 
Sbjct: 52  IILDDVNDNAPVFSRPEGYTFEVQEGGVGLSVGTVQATDRDSGINAATLYSLKSVADYSK 111

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            +     ID ++G + TS  LDRETQ +  + V A D G P  SA               
Sbjct: 112 FI-----IDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHR 166

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLT 389
             F   QY V + E       ++TLT
Sbjct: 167 PAFSQRQYSVTVQEKRASHV-ILTLT 191



 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 42/127 (33%), Positives = 66/127 (51%), Gaps = 8/127 (6%)

Query: 675 IKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
           I ++D+ND+ PVF   +  TF + E   +G ++G ++A D D G NA   YS+K   D +
Sbjct: 52  IILDDVNDNAPVFSRPEGYTFEVQEGG-VGLSVGTVQATDRDSGINAATLYSLKSVADYS 110

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNA 791
            F ++++ G  K    T   LD E+  +    VI     SP L  +V + + VTD+ND+ 
Sbjct: 111 KFIIDSKTGVIK----TSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHR 166

Query: 792 PVMKDFQ 798
           P     Q
Sbjct: 167 PAFSQRQ 173



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 42/153 (27%), Positives = 65/153 (42%), Gaps = 26/153 (16%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN+ D ND++PV     Y ASV E    G +VL +   D D   N +V +T+        
Sbjct: 1369 INIQDVNDNTPVLTSSTYTASVPENQPPGQSVLKISVFDPDHAGNGQVAFTVN------- 1421

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             + F ++  SG L T   LDRE  A Y + + ATD+   V +  
Sbjct: 1422 ----------------NNKFTVNDTSGVLYTTHVLDRETKASYQLTITATDKGI-VENMT 1464

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
              +  I V+ +D ++      +  Y++  D DI
Sbjct: 1465 VGSHVIKVSAVDPDEG--SNGDILYSLQTDYDI 1495



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 3/106 (2%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I   I + D ND  P F    Y   + E  + GT VL     D+D+G N ++ Y I    
Sbjct: 314 IEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGTNGQISYHISSGN 373

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVA 111
           ++T  P             V   F  D GR    L   + D+ + A
Sbjct: 374 SET--PPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPA 417



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 37/162 (22%), Positives = 76/162 (46%), Gaps = 12/162 (7%)

Query: 732  SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPLWNDVRVEILVTDV 787
            S++F+++   G  +A  V ++D +    +  Y L ++A       P W+   V + V D 
Sbjct: 1215 SHTFAIDPMTGDIRA--VGLLDRE---TKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDS 1269

Query: 788  NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNET 845
            NDNAPV K    +    +         +V A D DV    ++ Y I+SGN     +++ +
Sbjct: 1270 NDNAPVFKKQSYVVEMVEHSPTTFTVVKVEATDRDVGSNGRISYSIVSGNVDGAFVIDSS 1329

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRL 886
            +G +  +  ++    +   + V   DG +  ++A +Q+++ +
Sbjct: 1330 SGVIKPAQDIDREKIQRYLLGVQAQDGGSPTLQATVQVTINI 1371



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSA 186
           L++ AT+ +++ + NDN P+F+ K Y  +V E   + +  ++ ++ A D D  A NSA
Sbjct: 913 LATNATVVIDLENVNDNTPEFTRKAYLFNVREGSYIDNEKIVGRVSAIDRDKDAENSA 970



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 28/184 (15%)

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI- 767
           I A D D G N+ +HY I  G+  NSF+L+   GS    L T   LD E  R +Y L++ 
Sbjct: 236 ILATDSDRGINSALHYMIDSGNFGNSFTLDALTGS----LSTTGPLDRE-VRAEYTLLVF 290

Query: 768 -------RAASPPLWND------VRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF 813
                   +   PL +       + V I ++DVND+ P     Q +++    +   +G  
Sbjct: 291 VSDLQGNASLGIPLRDSAVVNVFIEVTITISDVNDSPPEFS--QAMYSVRIPENITLGTV 348

Query: 814 GRVPA---YDADVTDKLQYRILSGNNAN--LILLNETTGSMTLSPQLNTNV-PKLATMEV 867
              P+    D     ++ Y I SGN+       +N ++G++++S + + +   K  ++ +
Sbjct: 349 VLQPSCVDRDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVL 408

Query: 868 SVTD 871
           + TD
Sbjct: 409 TATD 412



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL 45
           +NV D NDH P F  +QY  +V+E  +S   +LTL
Sbjct: 157 VNVTDINDHRPAFSQRQYSVTVQEKRAS-HVILTL 190



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQVGATDADVGLN----G 614
           L+    V I + +VNDN P F ++ Y  N+ E + +     V +V A D D        G
Sbjct: 913 LATNATVVIDLENVNDNTPEFTRKAYLFNVREGSYIDNEKIVGRVSAIDRDKDAENSAYG 972

Query: 615 RIHY 618
           RI Y
Sbjct: 973 RIQY 976


>SB_15712| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 1075

 Score =  277 bits (680), Expect = 7e-74
 Identities = 244/890 (27%), Positives = 397/890 (44%), Gaps = 94/890 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREG---ASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            IN+ D +D    F  + YEA + +    A S T  L        +   + + Y + ++  
Sbjct: 211  INITDVDDLPANFSQKLYEAHIDKNSPLAKSTTQPLAFTLVKVTVSTLSNLTYDVSILEG 270

Query: 68   DT------LNPEDAXXXXXXXXXXVQD----VFRIDGRSGALLTRASLDREKVARYTVLV 117
            +       L P ++            D    +F I+G +   +    LDRE  A++ + +
Sbjct: 271  EANVPVMDLKPAESHFNVSGGNFTFFDSSGSMFSING-TNLRVGSTPLDRETAAQHILDI 329

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177
              T+  +     +     + VN++D ND  P F   ++ VSV+E   +    V   + AT
Sbjct: 330  SLTEGGT-----IKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERL--GTVFLTVSAT 382

Query: 178  DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
            D D GANSA+ Y+I  GN +  FSI++ +G +S+ K LD E    Y L + AQDGG P  
Sbjct: 383  DGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPL 442

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            ++TT + I + D NDN P    ++ Q S+SE   I   +  V A D D G N  L Y++ 
Sbjct: 443  NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSI- 501

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP---PRSATATXXX 354
            +    G+  +    D  SG +  +G L    +  Y ++V  TDGG P    R+       
Sbjct: 502  ESGALGHFQIK---DWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVT 558

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPP--GTPVVTLTATDAD--EDNRLHYEITGGNTRG 410
                        + G+  V++ + +     TPV T+ A+D D   + RL Y I  G   G
Sbjct: 559  PKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPVATVIASDKDIGANGRLMYSIESG-AHG 617

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPV 468
             F I   +  G I++A  L + Q   Y++ V+ TD G  +    AMV I++T      P 
Sbjct: 618  HFQI-KDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PK 670

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQQFVIN 527
              N  Y  SV E       V+ +   +S   ++    T+  SS             F IN
Sbjct: 671  PRNLTYDVSVLE-GEANVQVMDLKPAESHFNMSGGNFTFFDSS----------GSMFSIN 719

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
              T     +  LDRET + ++L ++  +GG  ++     V ++V+D+ND  P+F+   + 
Sbjct: 720  -GTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFN 776

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
             ++ E   +GT    V ATD D G N  + Y +   + E  S                ++
Sbjct: 777  VSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEAVS----------------NK 820

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
             S+ + DL  +A+            V + + DIND  P+F+S      ++E   +GT   
Sbjct: 821  NSLISEDLSYIALQ-----------VTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFL 869

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
             + A D D G N+ + YSI  G++   FS+  + G+    +     LD E+ R +Y L +
Sbjct: 870  TVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTV 924

Query: 768  RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV- 823
             A     PPL +   V I V D NDN PV++D  I  +  +      P   V A D D+ 
Sbjct: 925  MAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIG 984

Query: 824  -TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
               +L Y I SG + +  + + ++G+++L+  L+ N      + V+VTDG
Sbjct: 985  ANGRLMYSIESGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1034



 Score =  216 bits (528), Expect = 2e-55
 Identities = 232/792 (29%), Positives = 349/792 (44%), Gaps = 82/792 (10%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           FRI+  +G L+   +LDRE +      ++    AS  S + S TA +   I D NDN P 
Sbjct: 58  FRINSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAIL--TITDINDNAPA 115

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F     TVS  E+  +     +A + ATDAD   N+ I + I+ GN    FSID ++GD+
Sbjct: 116 FQNTPLTVSCSENRPI--GLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDI 173

Query: 210 SLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVS 267
           ++ K LDYE   R Y L I A +  +     +  ++ INI DV+D    F   L++  + 
Sbjct: 174 TISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHID 233

Query: 268 ENVPIGYSIVRVQAY---DADEGVNAELTYTMTDKDYTGNV---DLP------------I 309
           +N P+  S  +  A+          + LTY ++  +   NV   DL              
Sbjct: 234 KNSPLAKSTTQPLAFTLVKVTVSTLSNLTYDVSILEGEANVPVMDLKPAESHFNVSGGNF 293

Query: 310 TIDPRSGWVYT---------SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
           T    SG +++         S  LDRET A++ L ++ T+GG        T         
Sbjct: 294 TFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVT--VNVLDIN 351

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418
                F    + V + E E  GT  +T++ATD D   ++ L Y I  GN  G FSI   N
Sbjct: 352 DETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSI--NN 409

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
             G I+VA+ LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    
Sbjct: 410 KTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQV 469

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ E A I T V  V A+D D+G N ++ YS+ S     A+ H     + +  +GAI+  
Sbjct: 470 SLSETAEIDTPVATVIASDKDIGANGRLMYSIES----GALGHFQ---IKDWSSGAISLA 522

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANI----M 591
            +L     + Y++ V   DGG P+L     V I V     N       L   AN+    +
Sbjct: 523 GMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVSVLEGEANVQVMDL 582

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESV 650
           + A + T V+ V A+D D+G NGR+ Y ++      G F I D +SG I     L     
Sbjct: 583 KTAEIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQR 640

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
             + +     DGG+P   S  +V I   D+   P       LT+ +S         GE  
Sbjct: 641 NNYIVVVNVTDGGSPALKSRAMVVI---DVTPKP-----RNLTYDVS------VLEGEAN 686

Query: 711 AHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
               D  P A  H+++ GG+ +   +S S+ +  G++    V    LD E+  +    + 
Sbjct: 687 VQVMDLKP-AESHFNMSGGNFTFFDSSGSMFSINGTNLR--VGSTPLDRETAAQHILDIS 743

Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDAD--V 823
                 +   V+V + V D+ND  P+ +   F +  N  +    V  F  V A D D   
Sbjct: 744 LTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGA 801

Query: 824 TDKLQYRILSGN 835
              L Y I  GN
Sbjct: 802 NSALTYSIAVGN 813



 Score =  213 bits (520), Expect = 2e-54
 Identities = 209/676 (30%), Positives = 304/676 (44%), Gaps = 85/676 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ PV +    + S+ E A   T V T+ A+D+DIG N  + Y+IE       
Sbjct: 450  IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 502

Query: 71   NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               F+I D  SGA+     L   +   Y V+V  TD  SP    
Sbjct: 503  -------------SGALGHFQIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 546

Query: 130  LSSTATIHVNIIDDNDNYPQ---FSEKTYTVSV-DEDISVTDNPVIAKIKATDADVGANS 185
            L S A + +++     N        E    V V D   +  D PV A + A+D D+GAN 
Sbjct: 547  LKSRAIVVIDVTPKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPV-ATVIASDKDIGANG 605

Query: 186  AIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
             + Y+I  G     F I DS SG +SL   L Y Q  +Y +V+   DGGSP+  +   ++
Sbjct: 606  RLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVV 664

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            I++       PR  T  +  SV E    G + V+V      E          T  D +G+
Sbjct: 665  IDVTP----KPRNLT--YDVSVLE----GEANVQVMDLKPAESHFNMSGGNFTFFDSSGS 714

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +      + R G    S  LDRET A++ L ++ T+GG        T             
Sbjct: 715  MFSINGTNLRVG----STPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPL- 769

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422
             F    + V + E E  GT  +T++ATD D   ++ L Y I  GN     +++++N   L
Sbjct: 770  -FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEE---AVSNKNS--L 823

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            I+        ++  Y+                V +N+ D N+  P+F++  +  SV E  
Sbjct: 824  IS--------EDLSYI-------------ALQVTVNVLDINDETPLFQSPSFNVSVNEIE 862

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +GT  L VSATD D G N+ +TYS+       A  + +  F IN +TGAI+  K LDRE
Sbjct: 863  RLGTVFLTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRE 915

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            T   Y LTV A+DGG P L+ TT V I V D NDN PV +  +   ++ E A + T V+ 
Sbjct: 916  TRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVAT 975

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAID 661
            V A+D D+G NGR+ Y ++      G F I D +SG I     L       + +     D
Sbjct: 976  VIASDKDIGANGRLMYSIE--SGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTD 1033

Query: 662  GGTPPQSSTVIVHIKI 677
            GG+P   S  +V I +
Sbjct: 1034 GGSPALKSRAMVVIDV 1049



 Score =  210 bits (513), Expect = 1e-53
 Identities = 220/794 (27%), Positives = 346/794 (43%), Gaps = 95/794 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND++P F+      S  E    G TV TL ATD D   NA + + I  V+ +  
Sbjct: 104 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI--VSGNE- 160

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
                            + F ID  +G +     LD E   R YT+ + A +  + +   
Sbjct: 161 ----------------GEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDL--M 202

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI----SVTDNPVIAKIKATDA------ 179
           L S   + +NI D +D    FS+K Y   +D++     S T       +K T +      
Sbjct: 203 LQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPLAKSTTQPLAFTLVKVTVSTLSNLT 262

Query: 180 -DVG-----ANSAI--------RYAIIGGN------TQMQFSIDSLSGDVSLVKTLDYEQ 219
            DV      AN  +         + + GGN      +   FSI+  +  V     LD E 
Sbjct: 263 YDVSILEGEANVPVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGST-PLDRET 321

Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
              + L I   +GG  +     ++ +N+ D+ND  P F +  F  SV+E   +G   + V
Sbjct: 322 AAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTV 379

Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
            A D D G N+ LTY++      GN +   +I+ ++G +  + QLDRET+ +Y L V A 
Sbjct: 380 SATDGDAGANSALTYSIA----VGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQ 435

Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397
           DGG+PP ++T                      +V L+E     TPV T+ A+D D   + 
Sbjct: 436 DGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANG 495

Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMV 455
           RL Y I  G   G F I   +  G I++A  L + Q   Y++ V+ TD G  +    A+V
Sbjct: 496 RLMYSIESG-ALGHFQIKDWSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIV 553

Query: 456 QINIT----DANNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            I++T    +  +   V E  A       + A I T V  V A+D D+G N ++ YS+  
Sbjct: 554 VIDVTPKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPVATVIASDKDIGANGRLMYSI-- 611

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
               E+ AH   Q + +  +GAI+   +L     + Y++ V   DGG P+L     V   
Sbjct: 612 ----ESGAHGHFQ-IKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMV--- 663

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           V+DV    P  +   Y  +++E       V  +   ++   ++G      D      GS 
Sbjct: 664 VIDVT---PKPRNLTYDVSVLEGE-ANVQVMDLKPAESHFNMSGGNFTFFD----SSGSM 715

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
                + +   +  LDRE+ A H L     +GGT      V V + + DIND  P+F+S 
Sbjct: 716 FSINGTNLRVGSTPLDRETAAQHILDISLTEGGT--IKGFVKVTVNVLDINDETPLFQSP 773

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD---SNSFSLETRQGSDKAE 747
                ++E   +GT    + A D D G N+ + YSI  G++   SN  SL +   S  A 
Sbjct: 774 SFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEAVSNKNSLISEDLSYIAL 833

Query: 748 LVT--MVDLDYESP 759
            VT  ++D++ E+P
Sbjct: 834 QVTVNVLDINDETP 847



 Score =  175 bits (427), Expect = 3e-43
 Identities = 179/660 (27%), Positives = 289/660 (43%), Gaps = 61/660 (9%)

Query: 255 PRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
           P F +  + + + E N   G  I R+ A     G N  +TY++ D  +         I+ 
Sbjct: 12  PTFGSPFWSDVLPEVNTTAGTIITRLTA----TGGNGTITYSLEDIAHPW-----FRINS 62

Query: 314 RSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
            +G +  +  LDRE        L       D     + T              F      
Sbjct: 63  STGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNTPLT 122

Query: 373 VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           V  +E+ P G  V TLTATDAD      + + I  GN    FSI    G   IT+++PLD
Sbjct: 123 VSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGD--ITISKPLD 180

Query: 431 FKQ-ERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG- 485
           ++   R Y L +SA ++          +V INITD ++    F    Y A + +++P+  
Sbjct: 181 YENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPLAK 240

Query: 486 --TTVLVVSATDSDVGINAQITYSLS---SEIS------NEAVAHHD---QQFVINPQTG 531
             T  L  +     V   + +TY +S    E +        A +H +     F     +G
Sbjct: 241 STTQPLAFTLVKVTVSTLSNLTYDVSILEGEANVPVMDLKPAESHFNVSGGNFTFFDSSG 300

Query: 532 AITT---------NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
           ++ +         +  LDRET + ++L ++  +GG  ++     V ++V+D+ND  P+F+
Sbjct: 301 SMFSINGTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQ 358

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
              +  ++ E   +GT    V ATD D G N  + Y +     EEG F I+  +G I   
Sbjct: 359 SPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AVGNEEGFFSINNKTGAISVA 417

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
           K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV +   +   +SE + I
Sbjct: 418 KQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI 477

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
            T +  + A D D G N  + YSI+ G     F ++    S    L  M  L Y + R  
Sbjct: 478 DTPVATVIASDKDIGANGRLMYSIESG-ALGHFQIKD-WSSGAISLAGM--LSY-NQRNN 532

Query: 763 YELVIR---AASPPLWNDVRVEILVTD-----VNDNAPVMKDFQIIFNNYKDCFPVGPFG 814
           Y +V+      SP L +   V I VT       +D + +  +  +   + K      P  
Sbjct: 533 YIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVSVLEGEANVQVMDLKTAEIDTPVA 592

Query: 815 RVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            V A D D+    +L Y I SG + +  + + ++G+++L+  L+ N      + V+VTDG
Sbjct: 593 TVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 652



 Score = 87.8 bits (208), Expect = 1e-16
 Identities = 74/240 (30%), Positives = 111/240 (46%), Gaps = 14/240 (5%)

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
           AP    +P+ + V  +  + TT   +    +  G N  ITYSL      E +AH    F 
Sbjct: 10  APPTFGSPFWSDVLPE--VNTTAGTIITRLTATGGNGTITYSL------EDIAH--PWFR 59

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQ 584
           IN  TG +  NK LDRE M   L ++        S S  +   I ++ D+NDN P F+  
Sbjct: 60  INSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNT 119

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
             T +  E+  +G +V+ + ATDAD   N  I + +     E  +F ID  +G I  +K 
Sbjct: 120 PLTVSCSENRPIGLTVATLTATDADATTNAIITFVI-VSGNEGEAFSIDKVTGDITISKP 178

Query: 645 LDRES-VATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
           LD E+    + L   A++  T     S  +V I I D++D P  F       +I +NSP+
Sbjct: 179 LDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPL 238



 Score = 74.1 bits (174), Expect = 1e-12
 Identities = 60/182 (32%), Positives = 92/182 (50%), Gaps = 17/182 (9%)

Query: 162 DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221
           +++ T   +I ++ AT    G N  I Y++        F I+S +GD+ + KTLD E + 
Sbjct: 25  EVNTTAGTIITRLTAT----GGNGTITYSL-EDIAHPWFRINSSTGDLIVNKTLDREAMG 79

Query: 222 ----SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
               S R  + A D  S S+ + T +L  I D+NDNAP F  +    S SEN PIG ++ 
Sbjct: 80  NGLGSLRFEVYASD--SSSQGSLTAIL-TITDINDNAPAFQNTPLTVSCSENRPIGLTVA 136

Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLV 336
            + A DAD   NA +T+ +     +GN     +ID  +G +  S  LD E   + Y L +
Sbjct: 137 TLTATDADATTNAIITFVIV----SGNEGEAFSIDKVTGDITISKPLDYENGPRVYTLNI 192

Query: 337 TA 338
           +A
Sbjct: 193 SA 194



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 51/206 (24%), Positives = 93/206 (45%), Gaps = 18/206 (8%)

Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           +PP F S   +  + E   + TT G I       G N  + YS++  D ++ +    R  
Sbjct: 10  APPTFGSPFWSDVLPE---VNTTAGTIITRLTATGGNGTITYSLE--DIAHPWF---RIN 61

Query: 743 SDKAELVTMVDLDYESPRK---KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI 799
           S   +L+    LD E+           + A+       +   + +TD+NDNAP  ++  +
Sbjct: 62  SSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNTPL 121

Query: 800 IFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLN 856
             +  ++  P+G     + A DAD T    + + I+SGN      +++ TG +T+S  L+
Sbjct: 122 TVSCSENR-PIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDITISKPLD 180

Query: 857 -TNVPKLATMEVSVTDGVNEIKAMMQ 881
             N P++ T+ +S  +  N    M+Q
Sbjct: 181 YENGPRVYTLNISAMN--NHTDLMLQ 204


>SB_36047| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 980

 Score =  274 bits (673), Expect = 5e-73
 Identities = 211/667 (31%), Positives = 315/667 (47%), Gaps = 39/667 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVAR----YTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           FRI+  +G L+   +LDRE +      +   V A+D +SP       +    + IID ND
Sbjct: 74  FRINSSTGDLIVNKTLDREAMGSGDGSFRFEVYASDGSSP-----QGSLRAFLTIIDIND 128

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
           N P F     T S  ED  V   PV+  + ATDAD   N+ I + I+ GN    FSID +
Sbjct: 129 NAPAFQNTPLTKSCSEDTPV-GFPVVT-VTATDADATTNAIITFVIVSGNEGEAFSIDKV 186

Query: 206 SGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQ 263
           +GD+++ K LDYE   R Y L I A +  +     +  ++ IN+ DV+D    F   L++
Sbjct: 187 TGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINVTDVDDLPANFSQKLYE 246

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSG 322
             + +N P+G  I +V A D D  +NA + Y++  D D  G       I+  SG V   G
Sbjct: 247 AHIDKNSPLGSFITQVHAEDMDS-LNAPVEYSIYPDSDPDGL----FAINKTSGAVTVDG 301

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            L       Y L+V A     PP                     + G+  V++ + +   
Sbjct: 302 NLKNGV---YSLIVNAKSTTQPPAFTLVKVTVGPLPNLTYAVTVLEGEANVQVMDLQVTV 358

Query: 383 TPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVL 439
               + + T      + H+  +GG         S+ S +G  L   + PLD +   ++VL
Sbjct: 359 ETRDSYSYTKRALPAKSHFNASGGTFTFFGSSGSMFSIDGAKLKVGSTPLDRETAAQHVL 418

Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            +S T+ G       V +N+ D N+  P F++  +  SV E   +GT +L V ATD D G
Sbjct: 419 DISLTEGGTVKGFVKVTVNVLDINDDRPSFQSPSFNVSVNEIERLGTVILTVFATDGDAG 478

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            N  +TYS+S+   NE     +  F IN +TGAI+  K LDRET   Y LTV A+DGG P
Sbjct: 479 ANGTLTYSISA--GNE-----EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP 531

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            L+ TT V I V D NDN PV +  +   ++ E A + T V+ V A+D D+G NGR+ Y 
Sbjct: 532 PLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYS 591

Query: 620 LDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
           ++      G F I D +SG I     L  +    + +     DGG+    S  IV I + 
Sbjct: 592 IE--SGAHGHFQIKDSSSGAISVAGVLSYKQWHNYTVVVKVTDGGSLALESRAIVLIDVT 649

Query: 679 DI--NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
               N + PVF S      + +++     +  + A D D G N VV Y I+  +D++ F 
Sbjct: 650 STTENRNGPVFASVQYIGGVYKDTSFDFPVLTVTATDSDTGVNGVVEYRIR--EDTDLFY 707

Query: 737 LETRQGS 743
           +E   G+
Sbjct: 708 VEPTSGT 714



 Score =  210 bits (513), Expect = 1e-53
 Identities = 206/715 (28%), Positives = 327/715 (45%), Gaps = 66/715 (9%)

Query: 162 DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221
           +++ T    I +  ATD D G N  I Y++   N    F I+S +GD+ + KTLD E + 
Sbjct: 40  EVNTTAGTNITRFTATDGD-GDN--ISYSL-QSNAHPWFRINSSTGDLIVNKTLDREAMG 95

Query: 222 S----YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
           S    +R  + A DG SP  S   +  + I D+NDNAP F  +   +S SE+ P+G+ +V
Sbjct: 96  SGDGSFRFEVYASDGSSPQGS--LRAFLTIIDINDNAPAFQNTPLTKSCSEDTPVGFPVV 153

Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLV 336
            V A DAD   NA +T+ +     +GN     +ID  +G +  S  LD E   + Y L +
Sbjct: 154 TVTATDADATTNAIITFVIV----SGNEGEAFSIDKVTGDITISKPLDYENGPRVYTLNI 209

Query: 337 TATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
           +A +   D    +                 F    YE  + ++ P G+ +  + A D D 
Sbjct: 210 SAMNNHTDLMLQSFGVVTINVTDVDDLPANFSQKLYEAHIDKNSPLGSFITQVHAEDMDS 269

Query: 396 DNR-LHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA 453
            N  + Y I    +  G F+I   +G   +TV   L   +   Y L V+A  +       
Sbjct: 270 LNAPVEYSIYPDSDPDGLFAINKTSGA--VTVDGNL---KNGVYSLIVNAKSTTQPPAFT 324

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
           +V++ +       P+  N  Y  +V E          V   D  V +  + +YS +   +
Sbjct: 325 LVKVTV------GPL-PNLTYAVTVLEGEAN------VQVMDLQVTVETRDSYSYTKR-A 370

Query: 514 NEAVAHHDQQ---FVINPQTGA---ITTNKL------LDRETMSGYLLTVTARDGGVPSL 561
             A +H +     F     +G+   I   KL      LDRET + ++L ++  +GG  ++
Sbjct: 371 LPAKSHFNASGGTFTFFGSSGSMFSIDGAKLKVGSTPLDRETAAQHVLDISLTEGG--TV 428

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
                V ++V+D+ND+ P F+   +  ++ E   +GT +  V ATD D G NG + Y + 
Sbjct: 429 KGFVKVTVNVLDINDDRPSFQSPSFNVSVNEIERLGTVILTVFATDGDAGANGTLTYSIS 488

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
             + EEG F I+  +G I   K LDRE+   + L  +A DGG PP +ST  V I++ D N
Sbjct: 489 AGN-EEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAN 547

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D+PPV +   +   +SE + I T +  + A D D G N  + YSI+ G   +    + + 
Sbjct: 548 DNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH---FQIKD 604

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILV----TDVNDNAPVMKD 796
            S  A  V  V L Y+     Y +V++      L  + R  +L+    T  N N PV   
Sbjct: 605 SSSGAISVAGV-LSYKQWHN-YTVVVKVTDGGSLALESRAIVLIDVTSTTENRNGPVFAS 662

Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM 849
            Q I   YKD     P   V A D+D  V   ++YRI    + +L  +  T+G++
Sbjct: 663 VQYIGGVYKDTSFDFPVLTVTATDSDTGVNGVVEYRI--REDTDLFYVEPTSGTI 715



 Score =  190 bits (462), Expect = 2e-47
 Identities = 185/672 (27%), Positives = 296/672 (44%), Gaps = 59/672 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + ++D ND++P F+      S  E    G  V+T+ ATD D   NA + + I  V+ +  
Sbjct: 121 LTIIDINDNAPAFQNTPLTKSCSEDTPVGFPVVTVTATDADATTNAIITFVI--VSGNE- 177

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
                            + F ID  +G +     LD E   R YT+ + A +  + +   
Sbjct: 178 ----------------GEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLM-- 219

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L S   + +N+ D +D    FS+K Y   +D++  +     I ++ A D D   N+ + Y
Sbjct: 220 LQSFGVVTINVTDVDDLPANFSQKLYEAHIDKNSPL--GSFITQVHAEDMD-SLNAPVEY 276

Query: 190 AII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           +I    +    F+I+  SG V++   L   +   Y L++ A+    P      ++ +   
Sbjct: 277 SIYPDSDPDGLFAINKTSGAVTVDGNL---KNGVYSLIVNAKSTTQPPAFTLVKVTVGPL 333

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD-ADEGVNAELTYTMTDKDYT--GNV 305
               N     T L  E+  + + +  ++    +Y      + A+  +  +   +T  G+ 
Sbjct: 334 P---NLTYAVTVLEGEANVQVMDLQVTVETRDSYSYTKRALPAKSHFNASGGTFTFFGSS 390

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
               +ID     V  S  LDRET A++ L ++ T+GG        T              
Sbjct: 391 GSMFSIDGAKLKV-GSTPLDRETAAQHVLDISLTEGGTVKGFVKVTVNVLDINDDRPS-- 447

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F    + V + E E  GT ++T+ ATD D   +  L Y I+ GN  G FSI   N  G I
Sbjct: 448 FQSPSFNVSVNEIERLGTVILTVFATDGDAGANGTLTYSISAGNEEGFFSIN--NKTGAI 505

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481
           +VA+ LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    S+ E 
Sbjct: 506 SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSET 565

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A I T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+   +L  
Sbjct: 566 AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISVAGVLSY 618

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTS 599
           +    Y + V   DGG  +L     V I V    +N   PVF    Y   + +D      
Sbjct: 619 KQWHNYTVVVKVTDGGSLALESRAIVLIDVTSTTENRNGPVFASVQYIGGVYKDTSFDFP 678

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKAL-DRESVATHDLKA 657
           V  V ATD+D G+NG + Y +    RE+   F ++P SG IRT     D++   +     
Sbjct: 679 VLTVTATDSDTGVNGVVEYRI----REDTDLFYVEPTSGTIRTADVFADKDEGQSFSFSV 734

Query: 658 VAIDGGTPPQSS 669
            A D GTPP+ +
Sbjct: 735 QASDKGTPPKET 746



 Score =  169 bits (410), Expect = 4e-41
 Identities = 185/663 (27%), Positives = 290/663 (43%), Gaps = 56/663 (8%)

Query: 251 NDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           N   P F + ++ +   E N   G +I R  A D D G N  ++Y++       N     
Sbjct: 23  NGAPPTFISPIWSDVFPEVNTTAGTNITRFTATDGD-GDN--ISYSLQS-----NAHPWF 74

Query: 310 TIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            I+  +G +  +  LDRE        ++  V A+DG  P  S  A               
Sbjct: 75  RINSSTGDLIVNKTLDREAMGSGDGSFRFEVYASDGSSPQGSLRA--FLTIIDINDNAPA 132

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLI 423
           F         +ED P G PVVT+TATDAD      + + I  GN    FSI    G   I
Sbjct: 133 FQNTPLTKSCSEDTPVGFPVVTVTATDADATTNAIITFVIVSGNEGEAFSIDKVTGD--I 190

Query: 424 TVAQPLDFKQERR-YVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVF 479
           T+++PLD++   R Y L +SA ++          +V IN+TD ++    F    Y A + 
Sbjct: 191 TISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINVTDVDDLPANFSQKLYEAHID 250

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           +++P+G+ +  V A D D  +NA + YS+  +      +  D  F IN  +GA+T +  L
Sbjct: 251 KNSPLGSFITQVHAEDMD-SLNAPVEYSIYPD------SDPDGLFAINKTSGAVTVDGNL 303

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
                  Y L V A+    P     T V+++V  + +           AN+    L  T 
Sbjct: 304 KNGV---YSLIVNAKSTTQPPAF--TLVKVTVGPLPNLTYAVTVLEGEANVQVMDLQVTV 358

Query: 600 VSQVGATDADVGLNGRIHYELDPKD----REEGS-FVIDPASGVIRTNKALDRESVATHD 654
            ++   +     L  + H+             GS F ID A   + +   LDRE+ A H 
Sbjct: 359 ETRDSYSYTKRALPAKSHFNASGGTFTFFGSSGSMFSIDGAKLKVGSTP-LDRETAAQHV 417

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           L     +GGT      V V + + DIND  P F+S      ++E   +GT I  + A D 
Sbjct: 418 LDISLTEGGTV--KGFVKVTVNVLDINDDRPSFQSPSFNVSVNEIERLGTVILTVFATDG 475

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
           D G N  + YSI  G++   FS+  + G+    +     LD E+ R +Y L + A     
Sbjct: 476 DAGANGTLTYSISAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGE 530

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829
           PPL +   V I V D NDN PV++D  I  +  +      P   V A D D+    +L Y
Sbjct: 531 PPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMY 590

Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN---EIKAMMQLSVRL 886
            I SG + +  + + ++G+++++  L+       T+ V VTDG +   E +A++ + V  
Sbjct: 591 SIESGAHGHFQIKDSSSGAISVAGVLSYKQWHNYTVVVKVTDGGSLALESRAIVLIDVTS 650

Query: 887 ITE 889
            TE
Sbjct: 651 TTE 653


>SB_9756| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 608

 Score =  268 bits (657), Expect = 4e-71
 Identities = 192/598 (32%), Positives = 303/598 (50%), Gaps = 60/598 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND+ P FE   Y  SV E A+ GT ++ L +TD D G+NA V Y   L+    +
Sbjct: 56  ITVLDENDNKPRFEAGAYNVSVYENATIGTVIVRLTSTDADQGRNAHVIYN--LLAGSGI 113

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              FR+D  +G +  +  LDRE +  +++ V  +D   P+    
Sbjct: 114 G-----------------TFRVDNTTGEITLQKPLDREVMDFFSLFVSVSD---PL---F 150

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+   + ++I+D N+  P F+ + Y V + E  +V    ++  + +TD D+G N+A+RYA
Sbjct: 151 SAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLV--VTSTDQDIGKNAAVRYA 208

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LLINIR 248
           I+ G+    F+++   G ++L K+LD E+  ++ L I A D G PS    T+  ++I++ 
Sbjct: 209 IVDGDPDGYFAVNDY-GVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVV 267

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDL 307
           D NDN P F  SL++ ++ EN   G S++ V+A D D +  N EL Y +      GN   
Sbjct: 268 DTNDNNPIFELSLYETTILENTTAGSSVLEVRADDGDSQSSNKELRYVIL-----GNCT- 321

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQL-----LVTATDGGDPPRSATATXXXXXXXXXXX 362
              ID  SG +YT+  +D E Q  Y+      ++ ATD G  PRSA A            
Sbjct: 322 DWHIDSLSGVIYTNNSVDYERQRVYEFQDFSFVLIATDNGTSPRSAHARVHITVNDVNDN 381

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420
              F P  Y+V ++E  P G  ++ LT +D D  E+++L+  +  G+    F +++    
Sbjct: 382 RPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFLSNS--- 438

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYTA 476
           G I++A+ LD+++ + Y LTV A DSG         A V I I D N+  PVF    Y A
Sbjct: 439 GEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYEA 498

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            V E+   G  V+ V A D+D   N ++ YS+           ++ +F +N  TG I  +
Sbjct: 499 WVLENITAGQFVVQVKAKDADYQQNGRLVYSM---------VRNNSKFRVNETTGEIYLS 549

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           + LD E    Y+  + A D GV   S +T V + V+DVNDN P F + LY + + E++
Sbjct: 550 ESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENS 607



 Score =  258 bits (632), Expect = 5e-68
 Identities = 190/617 (30%), Positives = 299/617 (48%), Gaps = 42/617 (6%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           L T  SLDRE ++ Y ++V+A +      + +++   I++ ++D+NDN P+F    Y VS
Sbjct: 20  LYTTRSLDRENISYYLLMVRARNIDEHAQEAITA---INITVLDENDNKPRFEAGAYNVS 76

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
           V E+ ++    VI ++ +TDAD G N+ + Y ++ G+    F +D+ +G+++L K LD E
Sbjct: 77  VYENATI--GTVIVRLTSTDADQGRNAHVIYNLLAGSGIGTFRVDNTTGEITLQKPLDRE 134

Query: 219 QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278
            +  + L +   D   P  S    + I+I DVN+  P F    +   +SE   +G +++ 
Sbjct: 135 VMDFFSLFVSVSD---PLFSAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLV 191

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           V + D D G NA + Y + D D  G   +        G +  +  LD E    + L +TA
Sbjct: 192 VTSTDQDIGKNAAVRYAIVDGDPDGYFAVN-----DYGVITLTKSLDSERNTTFNLTITA 246

Query: 339 TDGGDPP-RSAT-ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED 396
            D G P   +AT A               F    YE  + E+   G+ V+ + A D D  
Sbjct: 247 HDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYETTILENTTAGSSVLEVRADDGDSQ 306

Query: 397 N---RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL-----TVSATDSGG 448
           +    L Y I G  T       S    G+I     +D++++R Y        + ATD+G 
Sbjct: 307 SSNKELRYVILGNCTDWHIDSLS----GVIYTNNSVDYERQRVYEFQDFSFVLIATDNGT 362

Query: 449 --RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
             RS  A V I + D N+  PVFE   Y   V E AP+G T+L ++ +D+D   N+Q+  
Sbjct: 363 SPRSAHARVHITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLNL 422

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT-- 564
            + S   N         F+ N  +G I+  + LD E +  Y LTV A D G P L     
Sbjct: 423 RVVSGDPNSTF------FLSN--SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKP 474

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
            +V I + D NDN+PVF + LY A ++E+   G  V QV A DAD   NGR+ Y +    
Sbjct: 475 ANVVIRIRDDNDNQPVFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMV--- 531

Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
           R    F ++  +G I  +++LD E    +    +A D G  P+SS+  V + + D+ND+ 
Sbjct: 532 RNNSKFRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNV 591

Query: 685 PVFESDCLTFYISENSP 701
           P F+       + ENSP
Sbjct: 592 PTFDRFLYKSTVRENSP 608



 Score =  245 bits (600), Expect = 3e-64
 Identities = 193/598 (32%), Positives = 291/598 (48%), Gaps = 46/598 (7%)

Query: 315 SGWV--YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
           +GW+  YT+  LDRE  + Y L+V A +  +  + A                 F  G Y 
Sbjct: 15  NGWLGLYTTRSLDRENISYYLLMVRARNIDEHAQEAITAINITVLDENDNKPRFEAGAYN 74

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           V + E+   GT +V LT+TDAD+    H  Y +  G+  G F +   N  G IT+ +PLD
Sbjct: 75  VSVYENATIGTVIVRLTSTDADQGRNAHVIYNLLAGSGIGTFRV--DNTTGEITLQKPLD 132

Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
            +    + L VS +D    +    V I+I D N Y PVF    Y   + E + +GTT+LV
Sbjct: 133 REVMDFFSLFVSVSDPLFSAYQG-VTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLV 191

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           V++TD D+G NA + Y++            D  F +N   G IT  K LD E  + + LT
Sbjct: 192 VTSTDQDIGKNAAVRYAIVD-------GDPDGYFAVNDY-GVITLTKSLDSERNTTFNLT 243

Query: 551 VTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           +TA D G+PSL   T   V I VVD NDN P+F+  LY   I+E+   G+SV +V A D 
Sbjct: 244 ITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYETTILENTTAGSSVLEVRADDG 303

Query: 609 DV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK-----AVAIDG 662
           D    N  + Y +     +   + ID  SGVI TN ++D E    ++ +      +A D 
Sbjct: 304 DSQSSNKELRYVILGNCTD---WHIDSLSGVIYTNNSVDYERQRVYEFQDFSFVLIATDN 360

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
           GT P+S+   VHI + D+ND+ PVFE       +SE +P+G TI  +   D D   N+ +
Sbjct: 361 GTSPRSAHARVHITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQL 420

Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVR- 779
           +  +  GD +++F L     S+  E+     LDYE   + Y L + A  +  P+   ++ 
Sbjct: 421 NLRVVSGDPNSTFFL-----SNSGEISIARKLDYER-LQMYNLTVVAWDSGKPVLQSLKP 474

Query: 780 --VEILVTDVNDNAPVMKDFQIIFNNYK-DCFPVGPFG-RVPAYDADVTD--KLQYRILS 833
             V I + D NDN PV    + ++  +  +    G F  +V A DAD     +L Y ++ 
Sbjct: 475 ANVVIRIRDDNDNQPVFS--RDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMVR 532

Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
            N+     +NETTG + LS  L+    K     +  +D   E K+    SVR+I  ++
Sbjct: 533 NNSK--FRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKS-SSTSVRVIVMDV 587



 Score =  226 bits (553), Expect = 2e-58
 Identities = 176/601 (29%), Positives = 282/601 (46%), Gaps = 43/601 (7%)

Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
           ++LD E +  Y L++RA++    ++   T + I + D NDN PRF    +  SV EN  I
Sbjct: 24  RSLDRENISYYLLMVRARNIDEHAQEAITAINITVLDENDNKPRFEAGAYNVSVYENATI 83

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G  IVR+ + DAD+G NA + Y +      G       +D  +G +     LDRE    +
Sbjct: 84  GTVIVRLTSTDADQGRNAHVIYNLLAGSGIGT----FRVDNTTGEITLQKPLDREVMDFF 139

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
            L V+ +   DP  SA                 F P +Y VE++E    GT ++ +T+TD
Sbjct: 140 SLFVSVS---DPLFSAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGTTLLVVTSTD 196

Query: 393 AD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450
            D  ++  + Y I  G+  G F++   N  G+IT+ + LD ++   + LT++A D G  S
Sbjct: 197 QDIGKNAAVRYAIVDGDPDGYFAV---NDYGVITLTKSLDSERNTTFNLTITAHDKGMPS 253

Query: 451 ----DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQIT 505
                 A+V I++ D N+  P+FE + Y  ++ E+   G++VL V A D D    N ++ 
Sbjct: 254 LETATRAIVVIDVVDTNDNNPIFELSLYETTILENTTAGSSVLEVRADDGDSQSSNKELR 313

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY-----LLTVTARDGGVPS 560
           Y +    ++         + I+  +G I TN  +D E    Y        + A D G   
Sbjct: 314 YVILGNCTD---------WHIDSLSGVIYTNNSVDYERQRVYEFQDFSFVLIATDNGTSP 364

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            S    V I+V DVNDN PVF+   Y   + E A VG ++ ++  +D D   N +++  +
Sbjct: 365 RSAHARVHITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRV 424

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS--TVIVHIKIE 678
              D     F+ +  SG I   + LD E +  ++L  VA D G P   S     V I+I 
Sbjct: 425 VSGDPNSTFFLSN--SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIR 482

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           D ND+ PVF  D    ++ EN   G  + +++A D D   N  + YS+    +++ F + 
Sbjct: 483 DDNDNQPVFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMV--RNNSKFRVN 540

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKD 796
              G    E+     LD+E  ++    +I + S   P  +   V ++V DVNDN P    
Sbjct: 541 ETTG----EIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDR 596

Query: 797 F 797
           F
Sbjct: 597 F 597



 Score =  126 bits (305), Expect = 2e-28
 Identities = 83/261 (31%), Positives = 130/261 (49%), Gaps = 25/261 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ PVFE   Y+  V E A  G T+L L  +D D  +N+++   + +V+ D  
Sbjct: 373 ITVNDVNDNRPVFEPPYYQVMVSEYAPVGQTILRLTVSDNDTAENSQLN--LRVVSGDP- 429

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F +   SG +     LD E++  Y + V A D   PV   L
Sbjct: 430 ----------------NSTFFLSN-SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSL 472

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              A + + I DDNDN P FS   Y   V E+I  T    + ++KA DAD   N  + Y+
Sbjct: 473 KP-ANVVIRIRDDNDNQPVFSRDLYEAWVLENI--TAGQFVVQVKAKDADYQQNGRLVYS 529

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           ++  N++  F ++  +G++ L ++LD+E+ + Y   I A D G   +S++T + + + DV
Sbjct: 530 MVRNNSK--FRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDV 587

Query: 251 NDNAPRFYTSLFQESVSENVP 271
           NDN P F   L++ +V EN P
Sbjct: 588 NDNVPTFDRFLYKSTVRENSP 608



 Score =  122 bits (295), Expect = 3e-27
 Identities = 95/276 (34%), Positives = 134/276 (48%), Gaps = 16/276 (5%)

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
           V N   G  TT  L DRE +S YLL V AR+    +    T + I+V+D NDN+P F+  
Sbjct: 13  VTNGWLGLYTTRSL-DRENISYYLLMVRARNIDEHAQEAITAINITVLDENDNKPRFEAG 71

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
            Y  ++ E+A +GT + ++ +TDAD G N  + Y L       G+F +D  +G I   K 
Sbjct: 72  AYNVSVYENATIGTVIVRLTSTDADQGRNAHVIYNL-LAGSGIGTFRVDNTTGEITLQKP 130

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           LDRE +   D  ++ +    P  S+   V I I D+N+  PVF        ISE S +GT
Sbjct: 131 LDREVM---DFFSLFVSVSDPLFSAYQGVTIHILDVNEYRPVFTPQKYHVEISEASTVGT 187

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
           T+  + + D D G NA V Y+I  GD    F++     +D   +     LD E     + 
Sbjct: 188 TLLVVTSTDQDIGKNAAVRYAIVDGDPDGYFAV-----NDYGVITLTKSLDSER-NTTFN 241

Query: 765 LVIRA---ASPPLWNDVR--VEILVTDVNDNAPVMK 795
           L I A     P L    R  V I V D NDN P+ +
Sbjct: 242 LTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFE 277



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 6/144 (4%)

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEILVTDVND 789
           N+F L +   +    L T   LD E+    Y L++RA +           + I V D ND
Sbjct: 5   NTFRLASNVTNGWLGLYTTRSLDRENI-SYYLLMVRARNIDEHAQEAITAINITVLDEND 63

Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ--YRILSGNNANLILLNETTG 847
           N P  +      + Y++        R+ + DAD        Y +L+G+      ++ TTG
Sbjct: 64  NKPRFEAGAYNVSVYENATIGTVIVRLTSTDADQGRNAHVIYNLLAGSGIGTFRVDNTTG 123

Query: 848 SMTLSPQLNTNVPKLATMEVSVTD 871
            +TL   L+  V    ++ VSV+D
Sbjct: 124 EITLQKPLDREVMDFFSLFVSVSD 147


>SB_41246| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 660

 Score =  266 bits (651), Expect = 2e-70
 Identities = 217/728 (29%), Positives = 331/728 (45%), Gaps = 93/728 (12%)

Query: 32  VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91
           + EGA +   V+   A D+D G+N  + Y  EL++ +T                    F 
Sbjct: 2   ISEGAKANQDVIAAIAIDKDAGENKRLTY--ELISGNTGGD-----------------FT 42

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           +D  +G + T  +L+R++   Y + + A D   P     S+T  + + + D NDN P F+
Sbjct: 43  LDPNTGMIKTARNLERQQTFSYNLTIGAADHGLP---SFSATTRVSIVVGDLNDNNPVFN 99

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS--GDV 209
              Y+ +V E+  V  +  +  + ATDAD G N+ + Y++  G++   F   + S  G +
Sbjct: 100 PTNYSTTVFENSPVGTS--LLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKSNHGTI 157

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNAPRF----YTSLFQE 264
            +   LD E    Y L I A DGG P SR+     L+ I D NDN P+F    YT   QE
Sbjct: 158 EVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQE 217

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           +    VP+  +   + A D D   +A++ Y +   D      +  +I+PR+G + T    
Sbjct: 218 NSGPGVPVQMTS-SIMATDRDIESHADVRYRLNGSD-----SIQFSINPRTGVITTRAGT 271

Query: 325 DRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
             E+ A  ++++   D  D  PR                   F+P   +  ++E    G 
Sbjct: 272 GHESLA--EVVIHVLDANDNTPR-------------------FIPSSIQSTISEAASIGQ 310

Query: 384 PVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            V  +TA D D   + R+ + I  G+  G+F I   +G  ++ V+  LD + +  YVL V
Sbjct: 311 SVARVTANDPDSGLNGRIFFSINSGS-EGKFEIGRSDG--VVRVSGSLDREAKAVYVLNV 367

Query: 442 SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
           SA D     R     V + + D N+  P F    +   V E   +G+ ++  +ATD D G
Sbjct: 368 SAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQG 427

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            NA ITYS+S              F IN  TG++T  + LDRET   Y  TV ARDGG  
Sbjct: 428 SNAAITYSMSYP-----------GFAINSNTGSVTITRPLDRETKQAYSFTVHARDGG-- 474

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            L     V + + D NDN P F    Y  ++++   VGT V  V A D DVG NG + Y 
Sbjct: 475 GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYA 534

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL---------KAVAIDGGTPPQSST 670
           +    R+ G F ID  +G+I  NK + R  +              K  A D GT P+++ 
Sbjct: 535 IRDS-RDPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGSFVFKVEARDHGTSPRATN 593

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
           V V I I D  D  PVF +      I E+ PIG+++  +       G   ++ YSI  G 
Sbjct: 594 VTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEVVKKRAG--TIIMYSI--GS 649

Query: 731 DSNSFSLE 738
             N FS++
Sbjct: 650 SQNVFSID 657



 Score =  260 bits (636), Expect = 2e-68
 Identities = 199/655 (30%), Positives = 310/655 (47%), Gaps = 53/655 (8%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
           VIA I A D D G N  + Y +I GNT   F++D  +G +   + L+ +Q  SY L I A
Sbjct: 12  VIAAI-AIDKDAGENKRLTYELISGNTGGDFTLDPNTGMIKTARNLERQQTFSYNLTIGA 70

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
            D G PS S TT++ I + D+NDN P F  + +  +V EN P+G S++ V A DAD G N
Sbjct: 71  ADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQN 130

Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSA 348
           A +TY++T  D  G +   +T     G +  +G LDRE    Y L +TATDGG P  R+A
Sbjct: 131 AYVTYSVTAGDSHG-LFRAVT-KSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTA 188

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV---TLTATDADEDNR--LHYEI 403
            A               F   +Y   + E+  PG PV    ++ ATD D ++   + Y +
Sbjct: 189 IAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRDIESHADVRYRL 248

Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463
            G ++  +FSI  + G                  V+T  A    G    A V I++ DAN
Sbjct: 249 NGSDSI-QFSINPRTG------------------VITTRA--GTGHESLAEVVIHVLDAN 287

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           +  P F  +   +++ E A IG +V  V+A D D G+N +I +S++S          + +
Sbjct: 288 DNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSG--------SEGK 339

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F I    G +  +  LDRE  + Y+L V+A DG          V +++ DVNDN P F +
Sbjct: 340 FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTK 399

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
             +  ++ E   VG+ +    ATD D G N  I Y +         F I+  +G +   +
Sbjct: 400 PAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSM-----SYPGFAINSNTGSVTITR 454

Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            LDRE+   +     A DGG     S V V+++I D ND+ P F +      + + +P+G
Sbjct: 455 PLDRETKQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVG 512

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA-ELVTMVDL---DYESP 759
           T +  + A D D G N  V Y+I+   D   F+++   G     ++++ + L    + S 
Sbjct: 513 TIVLAVNAEDRDVGNNGHVTYAIRDSRDPGLFTIDANNGLITVNKIISRLQLGQSGFLSN 572

Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
              +   + A    + P   +V V I + D  D++PV      +    +D  P+G
Sbjct: 573 NGSFVFKVEARDHGTSPRATNVTVVINIVDSGDDSPVFNTSSYVVKIDED-RPIG 626



 Score =  252 bits (618), Expect = 2e-66
 Identities = 194/606 (32%), Positives = 288/606 (47%), Gaps = 72/606 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND++PVF    Y  +V E +  GT++L + ATD D G+NA V Y++     D+ 
Sbjct: 86  IVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSV--TAGDS- 142

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRS--GALLTRASLDREKVARYTVLVKATDQASPVSD 128
                             +FR   +S  G +    +LDRE    Y + + ATD   P+S 
Sbjct: 143 ----------------HGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISR 186

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSA 186
             ++ A   V I+D NDN P+FS   YT S+ E+ S    PV   + I ATD D+ +++ 
Sbjct: 187 --TAIAIALVRILDRNDNEPKFSHARYTGSIQEN-SGPGVPVQMTSSIMATDRDIESHAD 243

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           +RY  + G+  +QFSI+  +G ++                 RA  G      +  +++I+
Sbjct: 244 VRYR-LNGSDSIQFSINPRTGVIT----------------TRAGTG----HESLAEVVIH 282

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + D NDN PRF  S  Q ++SE   IG S+ RV A D D G+N  + +++     +G+ +
Sbjct: 283 VLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN----SGS-E 337

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               I    G V  SG LDRE +A Y L V+A DG   PR    T              F
Sbjct: 338 GKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKF 397

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
               + V+++E    G+ +V  TATD D+ +  +  IT   +   F+I S  G   +T+ 
Sbjct: 398 TKPAFNVDVSEGVAVGSVIVNATATDPDQGS--NAAITYSMSYPGFAINSNTGS--VTIT 453

Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           +PLD + ++ Y  TV A D GG      V + I D N+ +P F    Y   V +  P+GT
Sbjct: 454 RPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGT 513

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-- 544
            VL V+A D DVG N  +TY++         +     F I+   G IT NK++ R  +  
Sbjct: 514 IVLAVNAEDRDVGNNGHVTYAIRD-------SRDPGLFTIDANNGLITVNKIISRLQLGQ 566

Query: 545 SGYL-------LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           SG+L         V ARD G    +    V I++VD  D+ PVF    Y   I ED  +G
Sbjct: 567 SGFLSNNGSFVFKVEARDHGTSPRATNVTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIG 626

Query: 598 TSVSQV 603
           +SV  V
Sbjct: 627 SSVVMV 632



 Score =  248 bits (606), Expect = 7e-65
 Identities = 188/600 (31%), Positives = 281/600 (46%), Gaps = 58/600 (9%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           +SE       ++   A D D G N  LTY +     +GN     T+DP +G + T+  L+
Sbjct: 2   ISEGAKANQDVIAAIAIDKDAGENKRLTYELI----SGNTGGDFTLDPNTGMIKTARNLE 57

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           R+    Y L + A D G P  SAT                F P  Y   + E+ P GT +
Sbjct: 58  RQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSL 117

Query: 386 VTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
           + +TATDAD     +  Y +T G++ G F   +++  G I VA  LD +    Y LT++A
Sbjct: 118 LDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITA 177

Query: 444 TDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS---ATDSD 497
           TD G    R+  A+  + I D N+  P F +A YT S+ E++  G  V + S   ATD D
Sbjct: 178 TDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRD 237

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
           +  +A + Y L+   S         QF INP+TG ITT      E+++            
Sbjct: 238 IESHADVRYRLNGSDSI--------QFSINPRTGVITTRAGTGHESLA------------ 277

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
                   +V I V+D NDN P F      + I E A +G SV++V A D D GLNGRI 
Sbjct: 278 --------EVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIF 329

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           + ++     EG F I  + GV+R + +LDRE+ A + L   AIDG   P+     V + +
Sbjct: 330 FSIN--SGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTL 387

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
           +D+ND+ P F        +SE   +G+ I    A DPD+G NA + YS+        F++
Sbjct: 388 QDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSM----SYPGFAI 443

Query: 738 ETRQGSDKAELVTMV-DLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMK 795
            +  GS     VT+   LD E+ ++ Y   + A     L ++V V + + D NDN+P   
Sbjct: 444 NSNTGS-----VTITRPLDRET-KQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFP 497

Query: 796 DFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLS 852
             Q    +  D  PVG     V A D DV +   + Y I    +  L  ++   G +T++
Sbjct: 498 TVQ-YQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIRDSRDPGLFTIDANNGLITVN 556



 Score =  185 bits (451), Expect = 4e-46
 Identities = 152/488 (31%), Positives = 227/488 (46%), Gaps = 42/488 (8%)

Query: 392 DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GR 449
           DA E+ RL YE+  GNT G F++    G  +I  A+ L+ +Q   Y LT+ A D G    
Sbjct: 21  DAGENKRLTYELISGNTGGDFTLDPNTG--MIKTARNLERQQTFSYNLTIGAADHGLPSF 78

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           S T  V I + D N+  PVF    Y+ +VFE++P+GT++L V+ATD+D G NA +TYS++
Sbjct: 79  SATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVT 138

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVE 568
           +  S     H   + V     G I     LDRE    Y LT+TA DGGVP S +      
Sbjct: 139 AGDS-----HGLFRAVTKSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIAL 193

Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSV---SQVGATDADVGLNGRIHYELDPKDR 625
           + ++D NDNEP F    YT +I E++  G  V   S + ATD D+  +  + Y L+  D 
Sbjct: 194 VRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRDIESHADVRYRLNGSDS 253

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            +  F I+P +GVI T      ES+A                   V++H+   D ND+ P
Sbjct: 254 IQ--FSINPRTGVITTRAGTGHESLAE------------------VVIHVL--DANDNTP 291

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
            F    +   ISE + IG ++  + A+DPD G N  + +SI  G +      E  +    
Sbjct: 292 RFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGSEGK---FEIGRSDGV 348

Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NY 804
             +   +D + ++        I  +  P      V + + DVNDN P  K  +  FN + 
Sbjct: 349 VRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTP--KFTKPAFNVDV 406

Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864
            +   VG    V A   D        I    +     +N  TGS+T++  L+    +  +
Sbjct: 407 SEGVAVGSV-IVNATATDPDQGSNAAITYSMSYPGFAINSNTGSVTITRPLDRETKQAYS 465

Query: 865 MEVSVTDG 872
             V   DG
Sbjct: 466 FTVHARDG 473



 Score =  140 bits (338), Expect = 2e-32
 Identities = 128/404 (31%), Positives = 178/404 (44%), Gaps = 42/404 (10%)

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + E A     V+   A D D G N ++TY L S        +    F ++P TG I T +
Sbjct: 2   ISEGAKANQDVIAAIAIDKDAGENKRLTYELIS-------GNTGGDFTLDPNTGMIKTAR 54

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            L+R+    Y LT+ A D G+PS S TT V I V D+NDN PVF    Y+  + E++ VG
Sbjct: 55  NLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVG 114

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSF--VIDPASGVIRTNKALDRESVATHDL 655
           TS+  V ATDAD G N  + Y +   D   G F  V     G I     LDRE    ++L
Sbjct: 115 TSLLDVTATDADSGQNAYVTYSVTAGD-SHGLFRAVTKSNHGTIEVAGNLDREVNDFYNL 173

Query: 656 KAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI---GEIRA 711
              A DGG P  +++  I  ++I D ND+ P F     T  I ENS  G  +     I A
Sbjct: 174 TITATDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMA 233

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
            D D   +A V Y +  G DS  FS+  R G     + T     +ES     E+VI    
Sbjct: 234 TDRDIESHADVRYRL-NGSDSIQFSINPRTG----VITTRAGTGHES---LAEVVIH--- 282

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQ 828
                       V D NDN P       I +   +   +G    RV A D D  +  ++ 
Sbjct: 283 ------------VLDANDNTPRFIP-SSIQSTISEAASIGQSVARVTANDPDSGLNGRIF 329

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           + I SG+      +  + G + +S  L+     +  + VS  DG
Sbjct: 330 FSINSGSEGK-FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDG 372



 Score =  114 bits (274), Expect = 1e-24
 Identities = 94/338 (27%), Positives = 149/338 (44%), Gaps = 15/338 (4%)

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
           I E A     V    A D D G N R+ YEL       G F +DP +G+I+T + L+R+ 
Sbjct: 2   ISEGAKANQDVIAAIAIDKDAGENKRLTYELI-SGNTGGDFTLDPNTGMIKTARNLERQQ 60

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
             +++L   A D G P  S+T  V I + D+ND+ PVF     +  + ENSP+GT++ ++
Sbjct: 61  TFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDV 120

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            A D D G NA V YS+  GD    F   T+      E+   +D +       Y L I A
Sbjct: 121 TATDADSGQNAYVTYSVTAGDSHGLFRAVTKSNHGTIEVAGNLDREVND---FYNLTITA 177

Query: 770 AS---PPLWNDVRVEIL-VTDVNDNAPVMKDFQI---IFNNYKDCFPVGPFGRVPAYDAD 822
                P     + + ++ + D NDN P     +    I  N     PV     + A D D
Sbjct: 178 TDGGVPISRTAIAIALVRILDRNDNEPKFSHARYTGSIQENSGPGVPVQMTSSIMATDRD 237

Query: 823 VTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQ 881
           +      R  L+G+++    +N  TG +T   +  T    LA + + V D  +     + 
Sbjct: 238 IESHADVRYRLNGSDSIQFSINPRTGVIT--TRAGTGHESLAEVVIHVLDANDNTPRFIP 295

Query: 882 LSVR-LITEEMLLNSITVRLNDMTAEQFLSPLLGFFID 918
            S++  I+E   +     R+     +  L+  + F I+
Sbjct: 296 SSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN 333



 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 59/198 (29%), Positives = 95/198 (47%), Gaps = 23/198 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND+SP F   QY+  V +    GT VL + A D+D+G N  V Y I     D+ 
Sbjct: 484 VEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIR----DSR 539

Query: 71  NPEDAXXXXXXXXXXVQDVF-RID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           +P             V  +  R+  G+SG L    S        +   V+A D  +  S 
Sbjct: 540 DPGLFTIDANNGLITVNKIISRLQLGQSGFLSNNGS--------FVFKVEARDHGT--SP 589

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           R ++  T+ +NI+D  D+ P F+  +Y V +DED  +  + V+ ++        A + I 
Sbjct: 590 R-ATNVTVVINIVDSGDDSPVFNTSSYVVKIDEDRPIGSSVVMVEV----VKKRAGTIIM 644

Query: 189 YAIIGGNTQMQFSIDSLS 206
           Y+I  G++Q  FSID+L+
Sbjct: 645 YSI--GSSQNVFSIDNLT 660


>SB_55456| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 736

 Score =  242 bits (592), Expect = 3e-63
 Identities = 200/657 (30%), Positives = 311/657 (47%), Gaps = 50/657 (7%)

Query: 129 RLSSTATIHVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA---TDADVGAN 184
           R  ST  + + I DD NDN P F+E+ Y   + E    + N V  ++      D +V  +
Sbjct: 51  RNDSTLFLFLGIEDDYNDNAPVFTEQPYMAKIAETPFFSLNSVNGELTLGGPLDFEVARS 110

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL------VIRAQDGGSPSRS 238
             +             S  ++  +V+ +  +    ++S+ L         A +   P+ +
Sbjct: 111 YMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIASEVPDPNSN 170

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV--RVQAYDADEG-VNAELTYT 295
            T  +++ + DVNDN P F  S++   V E+V +   +V  ++Q  D D+  V   + Y 
Sbjct: 171 TTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYH 230

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXX 354
           +   D          IDP SG +Y +  LD E Q  +   V AT+     + SA A+   
Sbjct: 231 LVGADSD-----KFAIDPTSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTL 285

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRF 412
                      F    Y   + E+  PGT +  +TATDAD      L YE+ GG     F
Sbjct: 286 TLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQA-AYF 344

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVF 469
           S+ + NG   I+ AQ LD+   R+Y  ++   D GG       A V + + D N+  P F
Sbjct: 345 SVNADNGT--ISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEF 402

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
              PYT+ + E+ P GT V  V+ATD D G N ++++++S+    +   H    F IN  
Sbjct: 403 TGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISA---GDDGGH----FSING- 454

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL-YTA 588
           +G +TT + LDRET++ Y LTV+A D GV S      + ++V+D NDN P     L  T 
Sbjct: 455 SGLVTTARELDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQITDGLTITT 514

Query: 589 NIMEDALVGTSV-SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LD 646
           NI E A  GT + S + A D D G NG++ Y +   D     F ++ A+G ++ + A LD
Sbjct: 515 NISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR---FTLNSATGRLQISPAGLD 571

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE----SDCLTFYISENSPI 702
           RE   ++DL     D G+PP +++  VH+ I D+ND+ P F+        T+ I+ +   
Sbjct: 572 RELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGP 631

Query: 703 GT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
           GT   T+ +I A DPD   N  V YS+  GD+   F L+    S K +  T+    Y
Sbjct: 632 GTINKTLIDINATDPDADANGKVAYSL-SGDEHGFFRLDPVTTSAK-QAATITTTQY 686



 Score =  235 bits (575), Expect = 4e-61
 Identities = 189/640 (29%), Positives = 297/640 (46%), Gaps = 50/640 (7%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND++PVF  Q Y A + E     T   +L + + ++     +++ +       +  ED
Sbjct: 65  DYNDNAPVFTEQPYMAKIAE-----TPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAED 119

Query: 75  AXXXXXXXXXXVQ-DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133
                      V  +V  I       L    L  +++   T +  A++   P S+   +T
Sbjct: 120 LGVPKLESRTTVIIEVTDISDMPPRFLQSFYL--KEIEENTPI--ASEVPDPNSN---TT 172

Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRYAII 192
            T+ V ++D NDN P F +  Y   V ED+++    V  +++ TD D       + Y ++
Sbjct: 173 VTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLV 232

Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLLINIRDVN 251
           G ++  +F+ID  SG + + KTLDYE+  ++   V+  +   S   S    + + + +VN
Sbjct: 233 GADSD-KFAIDPTSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLINVN 291

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           DN P F  S +  ++ E +  G  I  + A DAD G    LTY     +  G      ++
Sbjct: 292 DNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTY-----ELRGGQAAYFSV 346

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQ 370
           +  +G +  +  LD +T  +YQ  +   DGG      A AT              F    
Sbjct: 347 NADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMP 406

Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           Y  ++AE+ P GT V  +TATD D  E+ RL + I+ G+  G FSI   NG GL+T A+ 
Sbjct: 407 YTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSI---NGSGLVTTARE 463

Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPIG 485
           LD +    Y LTVSA D G   R     + +N+ D N+  P + +    T ++ E A  G
Sbjct: 464 LDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQITDGLTITTNISEGAGGG 523

Query: 486 TTVL-VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRET 543
           T +L  ++A D D G N Q+TYS+S           D +F +N  TG +  +   LDRE 
Sbjct: 524 TVLLSSIAAVDPDAGSNGQLTYSMSG---------GDSRFTLNSATGRLQISPAGLDREL 574

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF----KQQLYTANIMEDALVGT- 598
              Y L +   D G P  +++T V ++++DVNDN P F     Q L T  I  D   GT 
Sbjct: 575 KDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTI 634

Query: 599 --SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636
             ++  + ATD D   NG++ Y L     E G F +DP +
Sbjct: 635 NKTLIDINATDPDADANGKVAYSL--SGDEHGFFRLDPVT 672



 Score =  192 bits (467), Expect = 5e-48
 Identities = 143/470 (30%), Positives = 237/470 (50%), Gaps = 35/470 (7%)

Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP-PGTPVVT-LTATDADE 395
           A++  DP  + T T              F+   Y  ++ ED   PG  V   L  TD D+
Sbjct: 161 ASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDK 220

Query: 396 D---NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--- 449
           +    R+ Y + G ++  +F+I   +G   + + + LD++++  +   V AT++      
Sbjct: 221 NPVFRRVLYHLVGADS-DKFAIDPTSGT--LYINKTLDYEKQINFTFDVVATETDTSEKF 277

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           S  A V + + + N+  P+F  + Y  ++ E+   GT +  ++ATD+D+G    +TY   
Sbjct: 278 SANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTY--- 334

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG--VPSLSDTTDV 567
            E+     A+    F +N   G I+  ++LD +T+  Y  ++  +DGG     ++  T V
Sbjct: 335 -ELRGGQAAY----FSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIAT-V 388

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            +++ DVNDN+P F    YT++I E+   GT V QV ATD D G NGR+ + +   D + 
Sbjct: 389 TVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGD-DG 447

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-V 686
           G F I+  SG++ T + LDRE++AT+ L   A D G   +   V + + + D ND+ P +
Sbjct: 448 GHFSIN-GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQI 506

Query: 687 FESDCLTFYISENSPIGTTI-GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
            +   +T  ISE +  GT +   I A DPD G N  + YS+ GGD  + F+L +  G  +
Sbjct: 507 TDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGD--SRFTLNSATGRLQ 564

Query: 746 AELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792
              ++   LD E  +  Y+L+I      SPP  N   V + + DVNDN P
Sbjct: 565 ---ISPAGLDREL-KDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTP 610



 Score =  152 bits (369), Expect = 3e-36
 Identities = 119/431 (27%), Positives = 193/431 (44%), Gaps = 27/431 (6%)

Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV--VSATDSDVG-INAQITYSL 508
           T  V + + D N+  P F  + Y   V ED  +   V+   +  TD D   +  ++ Y L
Sbjct: 172 TVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHL 231

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDV 567
                   V     +F I+P +G +  NK LD E    +   V A +       S    V
Sbjct: 232 --------VGADSDKFAIDPTSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASV 283

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            +++++VNDN+P+F +  Y   + E+   GT ++ + ATDAD+G  G + YEL  +  + 
Sbjct: 284 TLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYEL--RGGQA 341

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPPV 686
             F ++  +G I   + LD +++  +    V  DGG   Q   +  V + ++D+ND+ P 
Sbjct: 342 AYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPE 401

Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
           F     T  I+EN P GT + ++ A D D G N  + ++I  GDD   FS+    GS   
Sbjct: 402 FTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSI---NGS--G 456

Query: 747 ELVTMVDLDYESPRKKYELVIRAASPPL---WNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
            + T  +LD E+    Y L + A    +     DV++ + V D NDN P + D   I  N
Sbjct: 457 LVTTARELDRET-IATYTLTVSAYDHGVSSRHKDVQLTVNVLDENDNTPQITDGLTITTN 515

Query: 804 YKDCFPVGP--FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQ-LNTNVP 860
             +    G      + A D D     Q         +   LN  TG + +SP  L+  + 
Sbjct: 516 ISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFTLNSATGRLQISPAGLDRELK 575

Query: 861 KLATMEVSVTD 871
               + ++VTD
Sbjct: 576 DSYDLIINVTD 586



 Score =  138 bits (334), Expect = 6e-32
 Identities = 109/407 (26%), Positives = 184/407 (45%), Gaps = 43/407 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + +++ ND+ P+F    Y  ++ E  + GT +  + ATD D+G       T   +T +  
Sbjct: 285 LTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLG-------TFGALTYELR 337

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             + A              F ++  +G +     LD + + +Y   +   D      +  
Sbjct: 338 GGQAA-------------YFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQE-- 382

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + AT+ V + D NDN P+F+   YT  + E++      ++ ++ ATD D G N  + + 
Sbjct: 383 IAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPA--GTIVFQVTATDKDSGENGRLSFN 440

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I  G+    FSI+  SG V+  + LD E + +Y L + A D G  SR    QL +N+ D 
Sbjct: 441 ISAGDDGGHFSING-SGLVTTARELDRETIATYTLTVSAYDHGVSSRHKDVQLTVNVLDE 499

Query: 251 NDNAPRFYTSL-FQESVSENVPIGYSIV-RVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           NDN P+    L    ++SE    G  ++  + A D D G N +LTY+M+  D        
Sbjct: 500 NDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR------ 553

Query: 309 ITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            T++  +G +  S   LDRE +  Y L++  TD G PP + + T              F 
Sbjct: 554 FTLNSATGRLQISPAGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFD 613

Query: 368 PGQYE----VELAEDEPPGT---PVVTLTAT--DADEDNRLHYEITG 405
           P   +      +  DE PGT    ++ + AT  DAD + ++ Y ++G
Sbjct: 614 PNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSG 660



 Score =  126 bits (305), Expect = 2e-28
 Identities = 97/328 (29%), Positives = 159/328 (48%), Gaps = 37/328 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND+ P F    Y + + E   +GT V  + ATD+D G+N  + + I        
Sbjct: 390 VTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISA------ 443

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             +D               F I+G SG + T   LDRE +A YT+ V A D    VS R 
Sbjct: 444 -GDDGGH------------FSING-SGLVTTARELDRETIATYTLTVSAYDHG--VSSR- 486

Query: 131 SSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                + VN++D+NDN PQ ++  T T ++ E        +++ I A D D G+N  + Y
Sbjct: 487 HKDVQLTVNVLDENDNTPQITDGLTITTNISEGAG-GGTVLLSSIAAVDPDAGSNGQLTY 545

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           ++ GG++  +F+++S +G + +    LD E   SY L+I   D GSP  +N+T + + I 
Sbjct: 546 SMSGGDS--RFTLNSATGRLQISPAGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTIL 603

Query: 249 DVNDNAPRFYTSLFQE------SVSENV-PIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           DVNDN P F  +  Q       +V E    I  +++ + A D D   N ++ Y+++  ++
Sbjct: 604 DVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEH 663

Query: 302 TGNVDL-PITIDPRSGWVYTSGQLDRET 328
            G   L P+T   +     T+ Q  + T
Sbjct: 664 -GFFRLDPVTTSAKQAATITTTQYSKIT 690



 Score = 54.8 bits (126), Expect = 9e-07
 Identities = 43/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%)

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIG-------TTVLVVSATDSDVGINAQITYSLSS 510
           N+   +N  P          V E+A IG       +T+ +    + D   NA +     +
Sbjct: 19  NVVKGSNNIPYITTTNLALRVNENATIGIQGIRNDSTLFLFLGIEDDYNDNAPVF----T 74

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
           E    A       F +N   G +T    LD E    Y+L V A D GVP L   T V I 
Sbjct: 75  EQPYMAKIAETPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIE 134

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
           V D++D  P F Q  Y   I E+  + + V
Sbjct: 135 VTDISDMPPRFLQSFYLKEIEENTPIASEV 164



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 71/319 (22%), Positives = 131/319 (41%), Gaps = 26/319 (8%)

Query: 573 DVNDNEPVFKQQLYTANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELD----PK 623
           D NDN PVF +Q Y A I E        V   ++  G  D +V  +  +    +    PK
Sbjct: 65  DYNDNAPVFTEQPYMAKIAETPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPK 124

Query: 624 DREEGSFVIDPASGVIRTNKALDRESVAT-HDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
                + +I+         + L    +    +   +A +   P  ++TV V + + D+ND
Sbjct: 125 LESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIASEVPDPNSNTTVTVVVTVVDVND 184

Query: 683 SPPVFESDCLTFYISENSPI-GTTIG-EIRAHDPDEGP--NAVVHYSIKGGDDSNSFSLE 738
           + P F      F + E+  + G  +  +++  D D+ P    V+++ +  G DS+ F+++
Sbjct: 185 NRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLV--GADSDKFAID 242

Query: 739 TRQGSDKAELVTMVDLDYESP-RKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMK 795
              G+    L     LDYE      +++V      S     +  V + + +VNDN P+  
Sbjct: 243 PTSGT----LYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLINVNDNKPMFA 298

Query: 796 DFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSP 853
                +   ++  P      + A DAD+     L Y  L G  A    +N   G+++ + 
Sbjct: 299 KSSYNYTMDEEITPGTHIADITATDADLGTFGALTYE-LRGGQAAYFSVNADNGTISAAQ 357

Query: 854 QLNTNVPKLATMEVSVTDG 872
            L+ +  +     + V DG
Sbjct: 358 ILDYDTLRQYQFSLVVKDG 376


>SB_18678| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 727

 Score =  240 bits (587), Expect = 1e-62
 Identities = 189/605 (31%), Positives = 289/605 (47%), Gaps = 57/605 (9%)

Query: 152 EKTYTVS-VDEDISVTDNPVIAKIKATDADVGA-NSAIRYAIIGGNTQMQFSIDSLSGDV 209
           E T T+S   E    T    +  + ATD D    N  + YAI+ GN    F ID   G +
Sbjct: 97  EATKTMSCTPETCKSTSGLSVLTMSATDMDAEEINQRVNYAIVSGNEDGIFDIDFNKGVI 156

Query: 210 SLVKTLDYEQVRSYRLVIRAQ-----DGGSPSR--SNTTQLLINIRDVNDNAPRFYTSLF 262
            L + LD+EQ+  Y+L I A      D   P    SN T + +N+ D +D   RF    +
Sbjct: 157 RLARELDFEQLTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSY 216

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
             S+ EN  +G  +++V A D D+ +NA +TY + DK+ T  + +   I   +G +  +G
Sbjct: 217 SASIPENAAMGSVVMQVHAKDLDKSINAPVTYAI-DKE-TNPLRM-FNIANITGEITLNG 273

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            LDRET A+Y+L + A       +  T                 +P  Y   + E+   G
Sbjct: 274 SLDRETIAEYRLRILAYC--TIYQDHTEVLITVTDVNDNIPLFTLPS-YNTTVNENAAIG 330

Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           T V+ + A D D+     +          F I   +G  +I V   LD +++  Y +TV 
Sbjct: 331 TYVIQVQAEDIDQGVNASFIYEIAYASHEFVIGEHSG--IIIVNGTLDREKKDFYSITVI 388

Query: 443 ATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
           A +   S G      + + + D N+ +P+F  A Y++ ++E+ P GT V+ VSA DSD+G
Sbjct: 389 ARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIG 448

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG--- 556
            NA ++Y++ S+        H Q F IN + G ITT++ LDRE ++ + L VTA DG   
Sbjct: 449 SNAMVSYAVLSDAEG-----HYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPL 503

Query: 557 ----GVPSLSDTTD-------------------VEISVVDVNDNEPVFKQQLYTANIMED 593
               G+  L+ T D                   V ++V+D NDN PV  +  YT +I E+
Sbjct: 504 STISGLLQLNHTLDREVVSKHSLRVTASDRGGEVTVNVLDSNDNIPVCDKVYYTISIPEN 563

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
             VG S+  +  TD D G N  + Y +         FV+D  +G++  NK LD E   T 
Sbjct: 564 TSVGQSLIHLNCTDQDSGENAHLLYHM---VSGHSKFVVDNVTGIMSLNKLLDFEEKPTV 620

Query: 654 DLKAV-AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIR 710
              A+  ID G PP S  V V++ ++++ND+ P F  D  TF+ISE   +     +G + 
Sbjct: 621 FTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVS 680

Query: 711 AHDPD 715
           AHD D
Sbjct: 681 AHDLD 685



 Score =  210 bits (512), Expect = 2e-53
 Identities = 193/663 (29%), Positives = 311/663 (46%), Gaps = 97/663 (14%)

Query: 36  ASSGTTVLTLKATDQDIGK-NAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG 94
           ++SG +VLT+ ATD D  + N  V Y I  V+ +    ED              +F ID 
Sbjct: 111 STSGLSVLTMSATDMDAEEINQRVNYAI--VSGN----EDG-------------IFDIDF 151

Query: 95  RSGALLTRASLDREKVARYTVLVKA----TDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
             G +     LD E++ +Y + + A    T+      + LS+   + VN++D +D   +F
Sbjct: 152 NKGVIRLARELDFEQLTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRF 211

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDV 209
           +  +Y+ S+ E+ ++    V+ ++ A D D   N+ + YAI      ++ F+I +++G++
Sbjct: 212 NNYSYSASIPENAAM--GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEI 269

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
           +L  +LD E +  YRL I A         + T++LI + DVNDN P F    +  +V+EN
Sbjct: 270 TLNGSLDRETIAEYRLRILAY---CTIYQDHTEVLITVTDVNDNIPLFTLPSYNTTVNEN 326

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
             IG  +++VQA D D+GVNA   Y +    Y  +      I   SG +  +G LDRE +
Sbjct: 327 AAIGTYVIQVQAEDIDQGVNASFIYEIA---YASH---EFVIGEHSGIIIVNGTLDREKK 380

Query: 330 AKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
             Y + V A +        +  T              F    Y   + E+EPPGT V+ +
Sbjct: 381 DFYSITVIARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQV 440

Query: 389 TATDAD------------EDNRLHYE---ITGGN--------------TRGRFSITSQNG 419
           +A D+D             D   HY+   I   N              T  R  +T+ +G
Sbjct: 441 SANDSDIGSNAMVSYAVLSDAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDG 500

Query: 420 R------GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473
                  GL+ +   LD +   ++ L V+A+D GG      V +N+ D+N+  PV +   
Sbjct: 501 APLSTISGLLQLNHTLDREVVSKHSLRVTASDRGGE-----VTVNVLDSNDNIPVCDKVY 555

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           YT S+ E+  +G +++ ++ TD D G NA + Y +        V+ H  +FV++  TG +
Sbjct: 556 YTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHM--------VSGH-SKFVVDNVTGIM 606

Query: 534 TTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           + NKLLD  E  + + + +   D G P LS    V ++V +VNDN P F Q  YT  I E
Sbjct: 607 SLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISE 666

Query: 593 ------DALVG-TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
                  A+VG  S   + A  ++  L G++ Y L       G F ID  +GV+R   +L
Sbjct: 667 GDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTL---GNSTGPFAIDKDTGVLRAVGSL 723

Query: 646 DRE 648
           DRE
Sbjct: 724 DRE 726



 Score =  138 bits (333), Expect = 8e-32
 Identities = 136/485 (28%), Positives = 235/485 (48%), Gaps = 43/485 (8%)

Query: 485 GTTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           G +VL +SATD D   IN ++ Y++ S   NE     D  F I+   G I   + LD E 
Sbjct: 114 GLSVLTMSATDMDAEEINQRVNYAIVS--GNE-----DGIFDIDFNKGVIRLARELDFEQ 166

Query: 544 MSGYLLTVTA-----RDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           ++ Y L ++A      D  +P   LS+ T V ++V+D +D    F    Y+A+I E+A +
Sbjct: 167 LTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAM 226

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           G+ V QV A D D  +N  + Y +D +      F I   +G I  N +LDRE++A + L+
Sbjct: 227 GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEITLNGSLDRETIAEYRLR 286

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
            +A    T  Q  T ++ I + D+ND+ P+F        ++EN+ IGT + +++A D D+
Sbjct: 287 ILAY--CTIYQDHTEVL-ITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQ 343

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASP 772
           G NA   Y I     S+ F +    G     ++    LD E  +  Y + + A     S 
Sbjct: 344 GVNASFIYEIAYA--SHEFVI----GEHSGIIIVNGTLDREK-KDFYSITVIARETETSA 396

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQY 829
              ++V + +++ D NDN+P+          Y++  P G F  +V A D+D+     + Y
Sbjct: 397 GFHSNVTITVMLRDENDNSPIFSRALYSSPIYEN-EPPGTFVIQVSANDSDIGSNAMVSY 455

Query: 830 RILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--VNEIKAMMQLSVR 885
            +LS    +     +N   G++T S +L+        + V+ +DG  ++ I  ++QL+  
Sbjct: 456 AVLSDAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTISGLLQLNHT 515

Query: 886 LITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGN 945
           L  E +  +S+ V  +D   E  ++ L     D    I  C K   Y  S+ ++T V  +
Sbjct: 516 LDREVVSKHSLRVTASDRGGEVTVNVL-----DSNDNIPVCDKV-YYTISIPENTSVGQS 569

Query: 946 ILNVS 950
           +++++
Sbjct: 570 LIHLN 574



 Score =  133 bits (321), Expect = 2e-30
 Identities = 101/333 (30%), Positives = 165/333 (49%), Gaps = 33/333 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NVLD +D    F    Y AS+ E A+ G+ V+ + A D D   NA V Y I+  T    
Sbjct: 199 VNVLDADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKSINAPVTYAIDKET---- 254

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           NP                +F I   +G +    SLDRE +A Y + + A    +   D  
Sbjct: 255 NP--------------LRMFNIANITGEITLNGSLDRETIAEYRLRILA--YCTIYQDHT 298

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                + + + D NDN P F+  +Y  +V+E+ ++     + +++A D D G N++  Y 
Sbjct: 299 E----VLITVTDVNDNIPLFTLPSYNTTVNENAAI--GTYVIQVQAEDIDQGVNASFIYE 352

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIR 248
           I       +F I   SG + +  TLD E+   Y + + A++  + +   SN T + + +R
Sbjct: 353 I--AYASHEFVIGEHSGIIIVNGTLDREKKDFYSITVIARETETSAGFHSNVT-ITVMLR 409

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D NDN+P F  +L+   + EN P G  +++V A D+D G NA ++Y +   D  G+    
Sbjct: 410 DENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL-SDAEGHYQY- 467

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
             I+ ++G + TS +LDRE    ++L VTA+DG
Sbjct: 468 FKINAKNGTITTSRRLDRENITTFRLRVTASDG 500



 Score =  103 bits (248), Expect = 2e-21
 Identities = 155/625 (24%), Positives = 257/625 (41%), Gaps = 73/625 (11%)

Query: 273 GYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
           G S++ + A D D E +N  + Y +     +GN D    ID   G +  + +LD E   +
Sbjct: 114 GLSVLTMSATDMDAEEINQRVNYAIV----SGNEDGIFDIDFNKGVIRLARELDFEQLTQ 169

Query: 332 YQLLVTA----TDGGDPPRSATATXXXXXXXXXXXXXX---FMPGQYEVELAEDEPPGTP 384
           Y+L ++A    T+    P++  +                  F    Y   + E+   G+ 
Sbjct: 170 YKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAMGSV 229

Query: 385 VVTLTATDADEDNR--LHYEITGG-NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
           V+ + A D D+     + Y I    N    F+I +  G   IT+   LD +    Y L +
Sbjct: 230 VMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGE--ITLNGSLDRETIAEYRLRI 287

Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
            A  +  +  T ++ I +TD N+  P+F    Y  +V E+A IGT V+ V A D D G+N
Sbjct: 288 LAYCTIYQDHTEVL-ITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQGVN 346

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGA------ITTNKLLDRETMSGY----LLTV 551
           A   Y ++       +  H    ++N             T    + ET +G+     +TV
Sbjct: 347 ASFIYEIAYASHEFVIGEHSGIIIVNGTLDREKKDFYSITVIARETETSAGFHSNVTITV 406

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT--ANIMEDALVGTSVS-------- 601
             RD    S   +  +  S +  N+    F  Q+    ++I  +A+V  +V         
Sbjct: 407 MLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLSDAEGHYQ 466

Query: 602 --QVGATDADVGLNGRIHYELDPKDR-----EEGSFVIDPASGVIRTNKALDRESVATHD 654
             ++ A +  +  + R+  E     R      +G+  +   SG+++ N  LDRE V+ H 
Sbjct: 467 YFKINAKNGTITTSRRLDRENITTFRLRVTASDGA-PLSTISGLLQLNHTLDREVVSKHS 525

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           L+  A D G         V + + D ND+ PV +    T  I EN+ +G ++  +   D 
Sbjct: 526 LRVTASDRGGE-------VTVNVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQ 578

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL---VIRAAS 771
           D G NA + Y +  G   + F ++   G      +    LD+E     + +   VI    
Sbjct: 579 DSGENAHLLYHMVSG--HSKFVVDNVTGIMSLNKL----LDFEEKPTVFTVAIEVIDHGR 632

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV--GPFGRVPAYDAD------- 822
           PPL   V V + V +VNDN P        F   +  F V     G V A+D D       
Sbjct: 633 PPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCP 692

Query: 823 VTDKLQYRILSGNNANLILLNETTG 847
           +  KLQY +  GN+     +++ TG
Sbjct: 693 LCGKLQYTL--GNSTGPFAIDKDTG 715



 Score = 79.0 bits (186), Expect = 5e-14
 Identities = 61/214 (28%), Positives = 99/214 (46%), Gaps = 32/214 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NVLD ND+ PV +   Y  S+ E  S G +++ L  TDQD G+NA + Y   +V+    
Sbjct: 539 VNVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLY--HMVSG--- 593

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129
                              F +D  +G +     LD  EK   +TV ++  D   P    
Sbjct: 594 ----------------HSKFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRP---P 634

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA--- 186
           LS    ++V + + NDNYP F +  YT  + E     D+ ++  + A D D  +++    
Sbjct: 635 LSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLC 694

Query: 187 --IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
             ++Y +  GN+   F+ID  +G +  V +LD E
Sbjct: 695 GKLQYTL--GNSTGPFAIDKDTGVLRAVGSLDRE 726


>SB_22450| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2806

 Score =  238 bits (583), Expect = 4e-62
 Identities = 189/611 (30%), Positives = 297/611 (48%), Gaps = 45/611 (7%)

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSG------DVSLVKTLDYEQVRSYRLVIRAQDGGS 234
            V + + + + II GN Q  FS+DS         D+   K L+ E V SY L +  QD  +
Sbjct: 1234 VYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRT 1293

Query: 235  PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
                + T++ I + D NDN P F    + +++ E++P+  SI R++A DAD G N  + Y
Sbjct: 1294 KRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYY 1353

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            +  +K  +        I+P SG V  + +L    +  ++L V A D   PP    ++   
Sbjct: 1354 SFKEKTTS------FAINPISGVVSVAQKLSNSARI-HRLTVVARDRALPPSKPKSSRNC 1406

Query: 355  XXXXXXXXXXXFMPG---QYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNT 408
                       F P    + +++   +   G    TL   D D+ +       EIT GN 
Sbjct: 1407 QLIVNVQAVNQFSPEFSVKTQLQNVSEGTSGIVYATLGIIDKDKGSNGDIDRVEITSGNL 1466

Query: 409  RGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465
             G FSI S      + V +PLD +     Y +T++A D G   R+ + ++++N+ D N+ 
Sbjct: 1467 DGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDN 1526

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
             P F  + Y  ++ E API T VL V ATD D G N  I Y ++    NE       +F 
Sbjct: 1527 NPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITR--GNEL-----GKFE 1579

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS---DTTDVEISVVDVNDNEPVFK 582
            IN +TG I T   LD E+   + LTV A D GVP  S    T  V ++++D ND++P FK
Sbjct: 1580 INSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSRKISTVPVVVNILDANDHDPEFK 1638

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
               Y  ++ ED   GTSV  V A D D G NG++ Y L   +     F I+P +G+IRT 
Sbjct: 1639 APEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSL--ANLRPVPFEIEPDTGIIRTT 1696

Query: 643  KALDRESVATH--DLKAVAIDGGTPPQSST-VIVHIKIEDINDSPPVFESDCLTFYISEN 699
              LDR++      +L+  A D GTP +  T  +V ++++++ND+ PV +       +  N
Sbjct: 1697 TNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILVDRN 1756

Query: 700  SPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
            +P+G  I  + A D D    +  + Y    G+   +FSL+ + G    EL T   L    
Sbjct: 1757 APVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTG----ELRTARSL--RG 1810

Query: 759  PRKKYELVIRA 769
             ++++ L+I+A
Sbjct: 1811 LQREFTLIIKA 1821



 Score =  225 bits (550), Expect = 4e-58
 Identities = 195/616 (31%), Positives = 290/616 (47%), Gaps = 50/616 (8%)

Query: 87   QDVFRIDGRSGA------LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140
            Q +F +D R  +      + T   L+RE VA Y + V   D+ +    R      +++ +
Sbjct: 1250 QGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRTK---RTLDRTKVNITV 1306

Query: 141  IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200
             D NDN P F +K Y  ++ EDI +  +  IA+I+A DADVG N  I Y+     T   F
Sbjct: 1307 DDSNDNRPIFLKKKYLKTIPEDIPM--HTSIARIEAVDADVGPNGLIYYSFKEKTT--SF 1362

Query: 201  SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAPR 256
            +I+ +SG VS+ + L     R +RL + A+D       P  S   QL++N++ VN  +P 
Sbjct: 1363 AINPISGVVSVAQKLS-NSARIHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPE 1421

Query: 257  FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--LPITIDPR 314
            F      ++VSE    G     +   D D+G N ++      +  +GN+D    I   P 
Sbjct: 1422 FSVKTQLQNVSEGTS-GIVYATLGIIDKDKGSNGDIDRV---EITSGNLDGAFSIKSSPN 1477

Query: 315  SGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
               V     LDRE     Y + +TA D G P R+ +                F   +Y  
Sbjct: 1478 DYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYIT 1537

Query: 374  ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
             L+E  P  TPV+ + ATD D   +  + Y IT GN  G+F I S+ G+  I     LD+
Sbjct: 1538 NLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGKFEINSKTGQ--IYTKGDLDY 1595

Query: 432  KQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            +  +R+ LTV+A D       +  T  V +NI DAN++ P F+   Y   ++ED   GT+
Sbjct: 1596 ESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTS 1655

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSG 546
            V  VSA D D G N ++ YSL++             F I P TG I T   LDR+T +  
Sbjct: 1656 VFTVSAEDLDSGGNGKVRYSLAN--------LRPVPFEIEPDTGIIRTTTNLDRDTGLPE 1707

Query: 547  YL-LTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQ 602
            ++ L V A D G P   +T T V++ V ++NDN PV KQ  +  NI+ D  A VG  ++ 
Sbjct: 1708 FINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQ--FKCNILVDRNAPVGVLITT 1765

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A D D+    +             +F +DP +G +RT ++L R       L   A DG
Sbjct: 1766 VTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 1824

Query: 663  -GTPPQSSTVIVHIKI 677
                P +  VI+ I I
Sbjct: 1825 IQESPDTHPVILKISI 1840



 Score =  215 bits (524), Expect = 6e-55
 Identities = 220/832 (26%), Positives = 366/832 (43%), Gaps = 115/832 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV   N  SP F ++    +V EG +SG    TL   D+D G N +++  +E+ +    
Sbjct: 1410 VNVQAVNQFSPEFSVKTQLQNVSEG-TSGIVYATLGIIDKDKGSNGDID-RVEITSG--- 1464

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDR 129
            N + A             V +             LDRE     Y V + A D+ +PV + 
Sbjct: 1465 NLDGAFSIKSSPNDYAVQVIK------------PLDRELAPFGYNVTLTAYDKGTPVRN- 1511

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
               +  + VN++D+NDN P+F++  Y  ++ E ++    PV+ ++ ATD D G+N  I Y
Sbjct: 1512 --GSYVLRVNVLDENDNNPEFNQSRYITNLSE-LAPIHTPVL-RVLATDKDAGSNGNIMY 1567

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRS-NTTQLLINI 247
             I  GN   +F I+S +G +     LDYE  + + L + A DG    SR  +T  +++NI
Sbjct: 1568 VITRGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNI 1627

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D ND+ P F    +++ + E++  G S+  V A D D G N ++ Y++ +        +
Sbjct: 1628 LDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLR-----PV 1682

Query: 308  PITIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            P  I+P +G + T+  LDR+T       L V A+D G P R  T T              
Sbjct: 1683 PFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAP 1742

Query: 366  FMPGQYEVELAEDE--PPGTPVVTLTATD---ADEDNRLHYEITGGNTRGRFSITSQNGR 420
             +  Q++  +  D   P G  + T+TA D   +D+D  L Y+ T GNT   FS+  + G 
Sbjct: 1743 VLK-QFKCNILVDRNAPVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGE 1801

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQINITDANN-YAPVFENAPYTASV 478
              +  A+ L   Q R + L + ATD    S DT  V + I+      A   +N   T  V
Sbjct: 1802 --LRTARSLRGLQ-REFTLIIKATDGIQESPDTHPVILKISIVGGRQARKLQNHVSTKCV 1858

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
              D+P+    L +            + ++ ++++ N    HH                  
Sbjct: 1859 --DSPLYAKALKIKQEQKSYSSLQPLIFA-TAKLHNR---HHP----------------- 1895

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            + RET+S Y L ++A D G    S  T + + + DVND  PVF + +Y   + E+  VG 
Sbjct: 1896 VFRETISSYTLNISAVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYEVTLPENITVGQ 1955

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            +V+               H     KD+E+  + I+    +   + ++D + V        
Sbjct: 1956 TVT---------------HVHASDKDQEQEMYKIE----IQAMDSSVDNQKVG------- 1989

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
                      ST ++ + + DIND+ P+ +       + E+  +   +  I A DPD GP
Sbjct: 1990 ----------STHVI-VTLLDINDNSPIVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGP 2038

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
               + +S+   + +  F+++++ G  +        LD+E  +  Y L +R     SP L+
Sbjct: 2039 GGEIEFSLP--ESTRKFNIDSKSGVIRLR----QRLDFEQ-KSTYNLTVRVTDKGSPALF 2091

Query: 776  NDVRVEILVTDVNDN--APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825
             DV V + V DVN+N  APV        N++ D     P    P  + D  D
Sbjct: 2092 TDVEVVVNVLDVNENSLAPVFSGALEYPNSFDDIKSFSPTDFGPLENKDHED 2143



 Score =  210 bits (512), Expect = 2e-53
 Identities = 208/797 (26%), Positives = 343/797 (43%), Gaps = 81/797 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P+F  ++Y  ++ E     T++  ++A D D+G N  + Y+ +  T    
Sbjct: 1304 ITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS-- 1361

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSDR 129
                               F I+  SG +     L    ++ R TV+  A D+A P S  
Sbjct: 1362 -------------------FAINPISGVVSVAQKLSNSARIHRLTVV--ARDRALPPSKP 1400

Query: 130  LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI- 187
             SS    + VN+   N   P+FS KT   +V E    T   V A +   D D G+N  I 
Sbjct: 1401 KSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEG---TSGIVYATLGIIDKDKGSNGDID 1457

Query: 188  RYAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLL 244
            R  I  GN    FSI S   D  V ++K LD E     Y + + A D G+P R+ +  L 
Sbjct: 1458 RVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLR 1517

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            +N+ D NDN P F  S +  ++SE  PI   ++RV A D D G N  + Y +T  +  G 
Sbjct: 1518 VNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGK 1577

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXX 362
             +    I+ ++G +YT G LD E++ ++ L V A DG      + +T             
Sbjct: 1578 FE----INSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDH 1633

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRG 421
               F   +Y  +L ED  PGT V T++A D D         +  N R   F I    G  
Sbjct: 1634 DPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLRPVPFEIEPDTGII 1693

Query: 422  LITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478
              T     D        L V A+D G    R    +V++ + + N+ APV +       V
Sbjct: 1694 RTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILV 1753

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
              +AP+G  +  V+A D D+    Q +    S   N   A     F ++P+TG + T + 
Sbjct: 1754 DRNAPVGVLITTVTAIDIDISDKDQ-SLMYKSTFGNTGKA-----FSLDPKTGELRTARS 1807

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            L R     + L + A D G+    DT  V + +  V   +    Q   +   ++  L   
Sbjct: 1808 L-RGLQREFTLIIKATD-GIQESPDTHPVILKISIVGGRQARKLQNHVSTKCVDSPLYAK 1865

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            ++         +    + +  L P        +I   + +   +  + RE+++++ L   
Sbjct: 1866 ALK--------IKQEQKSYSSLQP--------LIFATAKLHNRHHPVFRETISSYTLNIS 1909

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A+D G   +S+  I+++KI D+ND  PVF+       + EN  +G T+  + A D D+  
Sbjct: 1910 AVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYEVTLPENITVGQTVTHVHASDKDQ-E 1968

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP---RKKYELVIRAASPPLW 775
              +    I+  D     S++ ++      +VT++D++  SP    KK+ + ++       
Sbjct: 1969 QEMYKIEIQAMDS----SVDNQKVGSTHVIVTLLDINDNSPIVKPKKFNVTVQ------- 2017

Query: 776  NDVRVEILVTDVNDNAP 792
             D+ V  +VT ++ + P
Sbjct: 2018 EDLLVNAVVTSIHASDP 2034



 Score =  177 bits (431), Expect = 1e-43
 Identities = 174/581 (29%), Positives = 260/581 (44%), Gaps = 44/581 (7%)

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            + TS +L+RE+ A Y+L V   D                         F+  +Y   + E
Sbjct: 1268 IKTSKRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPE 1327

Query: 378  DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
            D P  T +  + A DAD   +  ++Y      T   F+I   +G  +++VAQ L     R
Sbjct: 1328 DIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS--FAINPISG--VVSVAQKLS-NSAR 1382

Query: 436  RYVLTVSATDSG------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
             + LTV A D          S    + +N+   N ++P F       +V E    G    
Sbjct: 1383 IHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEGTS-GIVYA 1441

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI--NPQTGAITTNKLLDRETMS-G 546
             +   D D G N  I      EI++    + D  F I  +P   A+   K LDRE    G
Sbjct: 1442 TLGIIDKDKGSNGDID---RVEITS---GNLDGAFSIKSSPNDYAVQVIKPLDRELAPFG 1495

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y +T+TA D G P  + +  + ++V+D NDN P F Q  Y  N+ E A + T V +V AT
Sbjct: 1496 YNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLAT 1555

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D G NG I Y +  +  E G F I+  +G I T   LD ES    DL   A+DG  P 
Sbjct: 1556 DKDAGSNGNIMYVIT-RGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDG-VPL 1613

Query: 667  QS---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            QS   STV V + I D ND  P F++      + E+   GT++  + A D D G N  V 
Sbjct: 1614 QSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVR 1673

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRAAS--PPLWNDVR- 779
            YS+     +N   +      D   + T  +LD ++   ++  L +RA+    PL  +   
Sbjct: 1674 YSL-----ANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETET 1728

Query: 780  -VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK---LQYRILSG 834
             V++ V ++NDNAPV+K F+      ++  PVG     V A D D++DK   L Y+   G
Sbjct: 1729 LVKMRVKEMNDNAPVLKQFKCNILVDRNA-PVGVLITTVTAIDIDISDKDQSLMYKSTFG 1787

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
            N      L+  TG +  +  L   + +  T+ +  TDG+ E
Sbjct: 1788 NTGKAFSLDPKTGELRTARSLR-GLQREFTLIIKATDGIQE 1827



 Score =  161 bits (392), Expect = 6e-39
 Identities = 145/545 (26%), Positives = 241/545 (44%), Gaps = 39/545 (7%)

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL----IT 424
            G Y   + E  P GTPV           N + + I  GN +G FS+ S+         I 
Sbjct: 1210 GIYSAFIPEITPIGTPVKCDLKMGVYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIK 1269

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             ++ L+ +    Y L V   D   +   D   V I + D+N+  P+F    Y  ++ ED 
Sbjct: 1270 TSKRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDI 1329

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P+ T++  + A D+DVG N  I YS   + ++         F INP +G ++  + L   
Sbjct: 1330 PMHTSIARIEAVDADVGPNGLIYYSFKEKTTS---------FAINPISGVVSVAQKLSNS 1380

Query: 543  TMSGYLLTVTARDGGV----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
                + LTV ARD  +    P  S    + ++V  VN   P F  +    N+ E    G 
Sbjct: 1381 ARI-HRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSE-GTSGI 1438

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVI--DPASGVIRTNKALDRE-SVATHDL 655
              + +G  D D G NG I          +G+F I   P    ++  K LDRE +   +++
Sbjct: 1439 VYATLGIIDKDKGSNGDIDRVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNV 1498

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A D GTP ++ + ++ + + D ND+ P F        +SE +PI T +  + A D D
Sbjct: 1499 TLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKD 1558

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPL 774
             G N  + Y I  G++   F + ++ G    ++ T  DLDYES R++++L + A    PL
Sbjct: 1559 AGSNGNIMYVITRGNELGKFEINSKTG----QIYTKGDLDYES-RQRFDLTVAALDGVPL 1613

Query: 775  W----NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQ 828
                 + V V + + D ND+ P  K  +   + Y+D  P      V A D D     K++
Sbjct: 1614 QSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVR 1673

Query: 829  YRILSGNNANLILLNETTGSMTLSPQL--NTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
            Y  L+        +   TG +  +  L  +T +P+   ++V  +D    ++   +  V++
Sbjct: 1674 YS-LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKM 1732

Query: 887  ITEEM 891
              +EM
Sbjct: 1733 RVKEM 1737



 Score =  134 bits (325), Expect = 7e-31
 Identities = 100/335 (29%), Positives = 158/335 (47%), Gaps = 30/335 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++NVLD ND++P F   +Y  ++ E A   T VL + ATD+D G N  + Y I     + 
Sbjct: 1517 RVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVI--TRGNE 1574

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L                   F I+ ++G + T+  LD E   R+ + V A D   P+  R
Sbjct: 1575 LGK-----------------FEINSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSR 1616

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              ST  + VNI+D ND+ P+F    Y   + ED+  T    +  + A D D G N  +RY
Sbjct: 1617 KISTVPVVVNILDANDHDPEFKAPEYRKDLYEDL--TPGTSVFTVSAEDLDSGGNGKVRY 1674

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQDGGSPSRSNTTQLL-IN 246
            + +     + F I+  +G +     LD +        L +RA D G+P R  T  L+ + 
Sbjct: 1675 S-LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMR 1733

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            ++++NDNAP          V  N P+G  I  V A D D    ++   ++  K   GN  
Sbjct: 1734 VKEMNDNAPVLKQFKCNILVDRNAPVGVLITTVTAIDID---ISDKDQSLMYKSTFGNTG 1790

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
               ++DP++G + T+  L R  Q ++ L++ ATDG
Sbjct: 1791 KAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 1824



 Score = 94.3 bits (224), Expect = 1e-18
 Identities = 76/270 (28%), Positives = 135/270 (50%), Gaps = 16/270 (5%)

Query: 44   TLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA 103
            TL  +  D GK+ +  YTI  V    +N              + +   + G++   +  +
Sbjct: 1905 TLNISAVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYEVTLPENITV-GQTVTHVHAS 1963

Query: 104  SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
              D+E+   Y + ++A D +S  + ++ ST  I V ++D NDN P    K + V+V ED+
Sbjct: 1964 DKDQEQ-EMYKIEIQAMD-SSVDNQKVGSTHVI-VTLLDINDNSPIVKPKKFNVTVQEDL 2020

Query: 164  SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
             V  N V+  I A+D D G    I +++    +  +F+IDS SG + L + LD+EQ  +Y
Sbjct: 2021 LV--NAVVTSIHASDPDSGPGGEIEFSL--PESTRKFNIDSKSGVIRLRQRLDFEQKSTY 2076

Query: 224  RLVIRAQDGGSPSRSNTTQLLINIRDVNDN--APRFYTSLFQESVSENV----PIGYSIV 277
             L +R  D GSP+     ++++N+ DVN+N  AP F  +L   +  +++    P  +  +
Sbjct: 2077 NLTVRVTDKGSPALFTDVEVVVNVLDVNENSLAPVFSGALEYPNSFDDIKSFSPTDFGPL 2136

Query: 278  RVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
              + ++ D+ +  EL + + D    G VDL
Sbjct: 2137 ENKDHE-DDHLRLEL-WGLRDAVENGQVDL 2164



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 39/139 (28%), Positives = 68/139 (48%), Gaps = 24/139 (17%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  + +LD ND+SP+ + +++  +V+E       V ++ A+D D G   E+E+++     
Sbjct: 1992 HVIVTLLDINDNSPIVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSL----- 2046

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                PE                F ID +SG +  R  LD E+ + Y + V+ TD+ SP  
Sbjct: 2047 ----PESTRK------------FNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPA- 2089

Query: 128  DRLSSTATIHVNIIDDNDN 146
              L +   + VN++D N+N
Sbjct: 2090 --LFTDVEVVVNVLDVNEN 2106


>SB_9507| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 2735

 Score =  238 bits (583), Expect = 4e-62
 Identities = 223/811 (27%), Positives = 361/811 (44%), Gaps = 81/811 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I + D ND+ P+F    Y+  VRE    G  +    A D D G NA V Y+I       
Sbjct: 6   KIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSI------- 58

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           +N ED+            ++F I   +G L   ++LDRE ++R+ + ++A D   P   R
Sbjct: 59  INFEDSRS---------DNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVP---R 106

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           +S  A I + + D ND+ P+FS  ++ V +   ++   +  + + +A D D G N  +RY
Sbjct: 107 MSGLAQIVIIVDDVNDHAPRFSSGSFHVEI--PLNTPPDSRVFQARALDPDGGHNGLVRY 164

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           +II GN Q  FSI+ + G + L + L    +    + I+A+D G P RS+T  + I I  
Sbjct: 165 SIIQGNKQGYFSINHIDGSLFLDEKL--TTLEPIDIKIQARDMGQPERSSTADIRIFIH- 221

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           V    P+F +S F  +V+EN P G  +V + A   D      + Y++   +  GN     
Sbjct: 222 VQAGPPQFLSSPFVGNVTENEPKGAFVVHISAASLD-----PVMYSIVSGNEAGN----F 272

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMP 368
            + P  GW+ T   LD E Q++Y+++V A D      +                      
Sbjct: 273 RLHPGVGWLTTVRPLDNEKQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRN 332

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           G  E  + +D   G+ V+ + A DAD  + L Y I     R  FS+   N  G++T  + 
Sbjct: 333 GIIEGNVLKDVAVGSRVMVIDAVDADRSDILSYRIEDEKARRYFSV---NNEGVVTSTRV 389

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           L    +  Y+  VS +D+G     A     +     Y P  +      S+ E A +GT V
Sbjct: 390 LR-DLDSPYLFKVSVSDNGKPPMVAQAMARVV-LLKYQP--QQDQQRTSIQESAALGTRV 445

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
             +  T   +  NA+  YS+ S +        + +F ++P +G +     LD ET+  + 
Sbjct: 446 FTL-LTAKPIR-NAR--YSIVSPL--------ETKFRVDPYSGDVRVRSGLDYETVKTHR 493

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ----LYTANIMEDALVGTSVSQVG 604
            T  AR+    +     DV I+V D NDN P F       LY A +  + +  T V  + 
Sbjct: 494 FTAEARNTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLE 553

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           ATD D  LNG + Y L         F ++  +G I T    D   +  ++L   A D G 
Sbjct: 554 ATDPDSDLNGIVRYRLITNPGSH--FALNAVTGSITTRGRSDL-FLPWYNLTVEAFDLGK 610

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
           P   +  +V+++       PP+F      FY+ EN+P G TIG +   D      +++ Y
Sbjct: 611 PSLVTRAVVNVR---TGQFPPLFSRKEYAFYVDENTPRGYTIGTV---DAKSFSGSLLEY 664

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP------PLWNDV 778
            +  G     F L++  G     L     LD+E     Y + + A         PL ++ 
Sbjct: 665 MVIEGSGHKRFVLDSVTG----RLTLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEA 720

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
            V+I++ D+NDN P  + F++   +Y+D  P
Sbjct: 721 DVKIVLRDLNDNPP--EFFEL---SYRDTLP 746



 Score =  223 bits (544), Expect = 2e-57
 Identities = 187/600 (31%), Positives = 284/600 (47%), Gaps = 68/600 (11%)

Query: 11   INVLDCNDHSPVFEMQQ----YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I V D ND+ P F M +    Y A V     + T V TL+ATD D   N  V Y   L+T
Sbjct: 514  ITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRY--RLIT 571

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                NP                 F ++  +G++ TR   D   +  Y + V+A D   P 
Sbjct: 572  ----NPGSH--------------FALNAVTGSITTRGRSDLF-LPWYNLTVEAFDLGKP- 611

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               L + A ++V         P FS K Y   VDE+      P    I   DA   + S 
Sbjct: 612  --SLVTRAVVNVRT---GQFPPLFSRKEYAFYVDEN-----TPRGYTIGTVDAKSFSGSL 661

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGS----PSRSNTT 241
            + Y +I G+   +F +DS++G ++L + LD+E+  + Y + + A++  +    P +S   
Sbjct: 662  LEYMVIEGSGHKRFVLDSVTGRLTLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSE-A 720

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             + I +RD+NDN P F+   +++++ E+ P+G +++ V A D D GVN +  Y +  + +
Sbjct: 721  DVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQFF 780

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                    ++DP +GW+ T   LD ET   +  LV A D G+P R+ TA           
Sbjct: 781  --------SVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVND 832

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-R 420
                F    Y V +AED      V T+ ATD D D  + Y I  G+    F I ++ G  
Sbjct: 833  NAPRFSQSLYNVFVAEDAGSDQLVATVQATDKDND-PVTYSIASGDNTTNFVINNKTGVI 891

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN-APYTASVF 479
             L++  +P        Y + +SA+D G     AMV + I D NN+ PVF + A Y   V 
Sbjct: 892  KLVSNRKPELIGP--YYTMNISASD-GLHVSQAMVIVAIQDVNNHKPVFTDCASYHPVVM 948

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            ED P  T V+ V A D D G N ++ YS+  E    A+++    F I+ +TG +TT +  
Sbjct: 949  EDDPPNTFVMQVHADDQDTGANGEVIYSI--EKPPGALSY----FAIDDKTGIVTTLQSF 1002

Query: 540  DRETMSGYLLTVTARDGGVPS------LSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            DRE    Y + +  RDGG+ S      L     V+I + D ND++PVF+ + Y A I ED
Sbjct: 1003 DREEKPVYQIRIIGRDGGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKED 1062



 Score =  210 bits (514), Expect = 9e-54
 Identities = 183/632 (28%), Positives = 294/632 (46%), Gaps = 56/632 (8%)

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            RY+I+    + +F +D  SGDV +   LDYE V+++R    A++    +      ++I +
Sbjct: 458  RYSIVSP-LETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYANIDVIITV 516

Query: 248  RDVNDNAPRFYTS----LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             D NDN PRF  +    L+   VS N      +  ++A D D  +N  + Y +       
Sbjct: 517  EDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT----- 571

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            N      ++  +G + T G+ D      Y L V A D G P   +  T            
Sbjct: 572  NPGSHFALNAVTGSITTRGRSDLFLPW-YNLTVEAFDLGKP---SLVTRAVVNVRTGQFP 627

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
              F   +Y   + E+ P G  + T+ A      + L Y +  G+   RF + S  GR  +
Sbjct: 628  PLFSRKEYAFYVDENTPRGYTIGTVDAKSFS-GSLLEYMVIEGSGHKRFVLDSVTGR--L 684

Query: 424  TVAQPLDFKQERR-YVLTVSATDSGGR-----SDTAMVQINITDANNYAPVFENAPYTAS 477
            T+ +PLDF+++   Y++TVSA ++           A V+I + D N+  P F    Y  +
Sbjct: 685  TLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEADVKIVLRDLNDNPPEFFELSYRDT 744

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E AP+GTTVL V+A D D G+N Q  Y + S+            F ++P TG ITT +
Sbjct: 745  LPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQF-----------FSVDPYTGWITTKR 793

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD ET   +   V A+D G P+ + T  V + + +VNDN P F Q LY   + EDA   
Sbjct: 794  PLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVAEDAGSD 853

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              V+ V ATD D   N  + Y +   D    +FVI+  +GVI+       E +  +    
Sbjct: 854  QLVATVQATDKD---NDPVTYSIASGDNTT-NFVINNKTGVIKLVSNRKPELIGPYYTMN 909

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPD 715
            ++   G     + VIV   I+D+N+  PVF +DC +++  + E+ P  T + ++ A D D
Sbjct: 910  ISASDGLHVSQAMVIV--AIQDVNNHKPVF-TDCASYHPVVMEDDPPNTFVMQVHADDQD 966

Query: 716  EGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLD-YESPRKKYELVIR----- 768
             G N  V YSI+    + S F+++ + G     + T+   D  E P  +  ++ R     
Sbjct: 967  TGANGEVIYSIEKPPGALSYFAIDDKTGI----VTTLQSFDREEKPVYQIRIIGRDGGLG 1022

Query: 769  --AASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
                +  L    +V+I + D ND+ PV ++ Q
Sbjct: 1023 SSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQ 1054



 Score =  208 bits (507), Expect = 6e-53
 Identities = 180/618 (29%), Positives = 282/618 (45%), Gaps = 47/618 (7%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-- 193
           + + + D NDN P F++  Y V V E++      VI +  A D D GAN+ + Y+II   
Sbjct: 5   LKIQLGDVNDNPPLFAQPVYKVFVRENLQ--GGHVIGQFAARDPDKGANARVTYSIINFE 62

Query: 194 -GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
              +   FSI   +G ++ + TLD E +  + L I+A+D G P  S   Q++I + DVND
Sbjct: 63  DSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVND 122

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           +APRF +  F   +  N P    + + +A D D G N  + Y++      GN     +I+
Sbjct: 123 HAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQ----GNKQGYFSIN 178

Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
              G ++   +L   T     + + A D G P RS+TA               F+   + 
Sbjct: 179 HIDGSLFLDEKL--TTLEPIDIKIQARDMGQPERSSTA-DIRIFIHVQAGPPQFLSSPFV 235

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
             + E+EP G  VV ++A   D    + Y I  GN  G F +    G G +T  +PLD +
Sbjct: 236 GNVTENEPKGAFVVHISAASLDP---VMYSIVSGNEAGNFRL--HPGVGWLTTVRPLDNE 290

Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF---ENAPYTASVFEDAPIGTTVL 489
           ++ RY + V A D   R     V +N+ + N+  P F    N     +V +D  +G+ V+
Sbjct: 291 KQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVM 350

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
           V+ A D+D    + I   LS  I +E    +   F +N + G +T+ ++L R+  S YL 
Sbjct: 351 VIDAVDAD---RSDI---LSYRIEDEKARRY---FSVNNE-GVVTSTRVL-RDLDSPYLF 399

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            V+  D G P +       + ++     +P   QQ    +I E A +GT V  +    A 
Sbjct: 400 KVSVSDNGKPPMVAQAMARVVLLKY---QPQQDQQ--RTSIQESAALGTRVFTL--LTAK 452

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
              N R +  + P    E  F +DP SG +R    LD E+V TH   A A +       +
Sbjct: 453 PIRNAR-YSIVSPL---ETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYA 508

Query: 670 TVIVHIKIEDINDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            + V I +ED ND+ P F     +     Y+S N    T +  + A DPD   N +V Y 
Sbjct: 509 NIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYR 568

Query: 726 IKGGDDSNSFSLETRQGS 743
           +     S+ F+L    GS
Sbjct: 569 LITNPGSH-FALNAVTGS 585



 Score =  180 bits (439), Expect = 1e-44
 Identities = 163/589 (27%), Positives = 263/589 (44%), Gaps = 52/589 (8%)

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            INA++ YSL  E      A  ++ F I+  TG I     LD ET   Y L V  RD GVP
Sbjct: 1189 INAKLKYSLEYE------AKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVP 1242

Query: 560  -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
             S SDT  + + V+D ND  P F+   Y+A + ED  +G  + +V A D D G+     Y
Sbjct: 1243 LSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRVRAFDEDTGIYKIFKY 1302

Query: 619  ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
             +   D  +G F I+P +G +  NK+LDRE  + H L   A +   P       V +++ 
Sbjct: 1303 SIAGGD-PQGQFKINPDTGDLYINKSLDREKNSNHILTIRATNIAPPYWYGEASVGVQVL 1361

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP--NAVVHYSIKGGDDSNSFS 736
            D+ND+ P F+ +    ++ EN+P    I ++   DPD  P       + I+ G++ N F 
Sbjct: 1362 DVNDNGPQFKPEVYNVFVPENTPPPYVIEKLEVTDPDSDPQNGGPFKFGIRSGNEKNLFE 1421

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVI----RAASP--PLWNDVRVEILVTDVNDN 790
            L     ++   L T V  + E    KYELV+     A  P  P+ +   V + V D NDN
Sbjct: 1422 L-----TEDGVLKTRVTFNREE-TAKYELVVWAEDNAKHPEKPIKSFASVFVHVRDRNDN 1475

Query: 791  APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850
                   +++ N  +  F  G  G+V   D D  D+  Y ++    +    ++  +G++ 
Sbjct: 1476 QHEAGYLELVLNVLEGKFGGGIIGKVFVKDIDTDDERLYELID-RESEAFSVDRLSGAVI 1534

Query: 851  LSPQLNTNVPK-LATMEVSVTDGVNEIKAMMQLSVRLITEEMLL----NSITVRLNDMTA 905
              P    N P    +M V V+D  +  +  +  +V++I +++ L     S  +RL  ++ 
Sbjct: 1535 SKP----NPPSGEFSMRVKVSDRDSGFQPRVS-TVKIIVKKLPLAAVGKSTAIRLRGISR 1589

Query: 906  EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGD 965
            E F++  +  F + LA I+    EN+ +FSVQ    +T  +++V F+A            
Sbjct: 1590 ETFVAGYITSFKESLAEILRTTSENVDLFSVQ-TAALTSQVIDVRFAAH----------- 1637

Query: 966  PSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGF 1025
             SP+YSP  +   +   R  L + A  ++     + CV EPC     C   LK       
Sbjct: 1638 GSPYYSPEKMIALIKAMRKNLEK-AAYKLDSIGVDPCVLEPC-EHSSCHAQLKVPGTVDV 1695

Query: 1026 VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR 1074
            + +    F  I         C     G   E+  ++  C+   +G  CR
Sbjct: 1696 IGTGEQSFTSI--KADLVAVCDACHAGRRIESRCSEDFCK---NGGTCR 1739



 Score =  157 bits (381), Expect = 1e-37
 Identities = 168/629 (26%), Positives = 284/629 (45%), Gaps = 65/629 (10%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           +L I + DVNDN P F   +++  V EN+  G+ I +  A D D+G NA +TY++ + + 
Sbjct: 4   ELKIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFED 63

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
           + + +L  +I P +G +     LDRE  +++ L + A D G P  S  A           
Sbjct: 64  SRSDNL-FSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVND 122

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
               F  G + VE+  + PP + V    A D D   +  + Y I  GN +G FSI   +G
Sbjct: 123 HAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDG 182

Query: 420 R----GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473
                  +T  +P+D K        + A D G   RS TA ++I I       P F ++P
Sbjct: 183 SLFLDEKLTTLEPIDIK--------IQARDMGQPERSSTADIRIFI-HVQAGPPQFLSSP 233

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           +  +V E+ P G  V+ +SA   D      + YS+ S   NEA       F ++P  G +
Sbjct: 234 FVGNVTENEPKGAFVVHISAASLD-----PVMYSIVS--GNEA-----GNFRLHPGVGWL 281

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANI 590
           TT + LD E  S Y + V A D  + +     +V ++V++VNDN+P F   +  +   N+
Sbjct: 282 TTVRPLDNEKQSRYKIIVMAMD--LKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNV 339

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
           ++D  VG+ V  + A DAD   +  + Y ++  D +   +      GV+ + + L R+  
Sbjct: 340 LKDVAVGSRVMVIDAVDAD--RSDILSYRIE--DEKARRYFSVNNEGVVTSTRVL-RDLD 394

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
           + +  K    D G PP  +  +  + +  +   P   + D     I E++ +GT +  + 
Sbjct: 395 SPYLFKVSVSDNGKPPMVAQAMARVVL--LKYQP---QQDQQRTSIQESAALGTRVFTLL 449

Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
              P    NA   YSI    ++  F ++   G    ++     LDYE+  K +     A 
Sbjct: 450 TAKPIR--NA--RYSIVSPLET-KFRVDPYSG----DVRVRSGLDYETV-KTHRFTAEAR 499

Query: 771 SPPLWND-VRVEILVT--DVNDNAP--VMKDFQIIFNNYKDCFPVGPFG----RVPAYDA 821
           +     D   +++++T  D NDN P   M     ++  Y    P+             D+
Sbjct: 500 NTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDS 559

Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMT 850
           D+   ++YR+++ N  +   LN  TGS+T
Sbjct: 560 DLNGIVRYRLIT-NPGSHFALNAVTGSIT 587



 Score =  130 bits (314), Expect = 2e-29
 Identities = 99/329 (30%), Positives = 148/329 (44%), Gaps = 16/329 (4%)

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            G I +A  LD++ +R Y L V   DSG     SDTA + + + DAN+ AP FE   Y+A 
Sbjct: 1214 GEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAV 1273

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V ED  IG  +L V A D D GI     YS++             QF INP TG +  NK
Sbjct: 1274 VREDVDIGERLLRVRAFDEDTGIYKIFKYSIAG-------GDPQGQFKINPDTGDLYINK 1326

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE  S ++LT+ A +   P       V + V+DVNDN P FK ++Y   + E+    
Sbjct: 1327 SLDREKNSNHILTIRATNIAPPYWYGEASVGVQVLDVNDNGPQFKPEVYNVFVPENTPPP 1386

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              + ++  TD D        ++   +   E +       GV++T    +RE  A ++L  
Sbjct: 1387 YVIEKLEVTDPDSDPQNGGPFKFGIRSGNEKNLFELTEDGVLKTRVTFNREETAKYELVV 1446

Query: 658  VAIDGGTPPQ---SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
             A D    P+    S   V + + D ND+        L   + E    G  IG++   D 
Sbjct: 1447 WAEDNAKHPEKPIKSFASVFVHVRDRNDNQHEAGYLELVLNVLEGKFGGGIIGKVFVKDI 1506

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            D     +     +   +S +FS++   G+
Sbjct: 1507 DTDDERLYELIDR---ESEAFSVDRLSGA 1532



 Score =  128 bits (309), Expect = 6e-29
 Identities = 101/371 (27%), Positives = 167/371 (45%), Gaps = 14/371 (3%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            FRID  +G ++   +LD E    Y + VK  D   P+S   S TA++ V ++D ND  P+
Sbjct: 1207 FRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLS--FSDTASLTVEVLDANDRAPR 1264

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            F   +Y+  V ED+ + +   + +++A D D G     +Y+I GG+ Q QF I+  +GD+
Sbjct: 1265 FEPLSYSAVVREDVDIGER--LLRVRAFDEDTGIYKIFKYSIAGGDPQGQFKINPDTGDL 1322

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
             + K+LD E+  ++ L IRA +   P       + + + DVNDN P+F   ++   V EN
Sbjct: 1323 YINKSLDREKNSNHILTIRATNIAPPYWYGEASVGVQVLDVNDNGPQFKPEVYNVFVPEN 1382

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
             P  Y I +++  D D        +    +         +T D   G + T    +RE  
Sbjct: 1383 TPPPYVIEKLEVTDPDSDPQNGGPFKFGIRSGNEKNLFELTED---GVLKTRVTFNREET 1439

Query: 330  AKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL--AEDEPPGTPVV 386
            AKY+L+V A D    P +   +                  G  E+ L   E +  G  + 
Sbjct: 1440 AKYELVVWAEDNAKHPEKPIKSFASVFVHVRDRNDNQHEAGYLELVLNVLEGKFGGGIIG 1499

Query: 387  TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
             +   D D D+   YE+    +   FS+   +G     +++P     E    + VS  DS
Sbjct: 1500 KVFVKDIDTDDERLYELIDRESEA-FSVDRLSG---AVISKPNPPSGEFSMRVKVSDRDS 1555

Query: 447  GGRSDTAMVQI 457
            G +   + V+I
Sbjct: 1556 GFQPRVSTVKI 1566



 Score =  122 bits (294), Expect = 4e-27
 Identities = 99/335 (29%), Positives = 159/335 (47%), Gaps = 39/335 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND+ P F    Y  ++ E A  GTTVL++ A D D G N +  Y +E      
Sbjct: 723  KIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVE------ 776

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F +D  +G + T+  LD E    ++ LV A D  +P    
Sbjct: 777  -----------------SQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPAR-- 817

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TA + V + + NDN P+FS+  Y V V ED     + ++A ++ATD D   N  + Y
Sbjct: 818  -NGTARVIVELTNVNDNAPRFSQSLYNVFVAEDAG--SDQLVATVQATDKD---NDPVTY 871

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINIR 248
            +I  G+    F I++ +G + LV     E +   Y + I A DG   S++    +++ I+
Sbjct: 872  SIASGDNTTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHVSQA---MVIVAIQ 928

Query: 249  DVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVN++ P F   + +   V E+ P    +++V A D D G N E+ Y++  +   G +  
Sbjct: 929  DVNNHKPVFTDCASYHPVVMEDDPPNTFVMQVHADDQDTGANGEVIYSI--EKPPGALSY 986

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
               ID ++G V T    DRE +  YQ+ +   DGG
Sbjct: 987  -FAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGG 1020



 Score =  118 bits (284), Expect = 7e-26
 Identities = 92/324 (28%), Positives = 147/324 (45%), Gaps = 17/324 (5%)

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD--PK 623
           +++I + DVNDN P+F Q +Y   + E+   G  + Q  A D D G N R+ Y +     
Sbjct: 4   ELKIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFED 63

Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
            R +  F I P +GV+     LDRE ++ H L   A D G P  S    + I ++D+ND 
Sbjct: 64  SRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDH 123

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            P F S      I  N+P  + + + RA DPD G N +V YSI  G+    FS+    GS
Sbjct: 124 APRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGS 183

Query: 744 --DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
                +L T+  +D +   +      R+++     D+R+ I    V    P       + 
Sbjct: 184 LFLDEKLTTLEPIDIKIQARDMGQPERSSTA----DIRIFI---HVQAGPPQFLSSPFV- 235

Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP- 860
            N  +  P G F  V    A   D + Y I+SGN A    L+   G +T    L+     
Sbjct: 236 GNVTENEPKGAF--VVHISAASLDPVMYSIVSGNEAGNFRLHPGVGWLTTVRPLDNEKQS 293

Query: 861 --KLATMEVSVTDGVNEIKAMMQL 882
             K+  M + + + V++++ ++ +
Sbjct: 294 RYKIIVMAMDLKNRVSKVEVIVNV 317



 Score =  100 bits (240), Expect = 1e-20
 Identities = 103/400 (25%), Positives = 163/400 (40%), Gaps = 24/400 (6%)

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            +E +NA+L Y++   +Y    + P  ID  +G +  +  LD ET+  Y+L V   D G P
Sbjct: 1186 EERINAKLKYSL---EYEAKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVP 1242

Query: 345  -PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHY 401
               S TA+              F P  Y   + ED   G  ++ + A D D        Y
Sbjct: 1243 LSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRVRAFDEDTGIYKIFKY 1302

Query: 402  EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINI 459
             I GG+ +G+F I    G   + + + LD ++   ++LT+ AT+         A V + +
Sbjct: 1303 SIAGGDPQGQFKINPDTGD--LYINKSLDREKNSNHILTIRATNIAPPYWYGEASVGVQV 1360

Query: 460  TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
             D N+  P F+   Y   V E+ P    +  +  TD D        +       NE    
Sbjct: 1361 LDVNDNGPQFKPEVYNVFVPENTPPPYVIEKLEVTDPDSDPQNGGPFKFGIRSGNE---- 1416

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISVVDVND 576
                F +  + G + T    +RE  + Y L V A D        +     V + V D ND
Sbjct: 1417 -KNLFELT-EDGVLKTRVTFNREETAKYELVVWAEDNAKHPEKPIKSFASVFVHVRDRND 1474

Query: 577  NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636
            N+          N++E    G  + +V   D D   + R+ YEL   DRE  +F +D  S
Sbjct: 1475 NQHEAGYLELVLNVLEGKFGGGIIGKVFVKDIDTD-DERL-YEL--IDRESEAFSVDRLS 1530

Query: 637  GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
            G +  +K        +  +K    D G  P+ STV + +K
Sbjct: 1531 GAV-ISKPNPPSGEFSMRVKVSDRDSGFQPRVSTVKIIVK 1569



 Score = 92.7 bits (220), Expect = 4e-18
 Identities = 75/249 (30%), Positives = 116/249 (46%), Gaps = 32/249 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND +P FE   Y A VRE    G  +L ++A D+D G     +Y+I        
Sbjct: 1253 VEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRVRAFDEDTGIYKIFKYSI-------- 1304

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            Q  F+I+  +G L    SLDREK + + + ++AT+ A P     
Sbjct: 1305 -----------AGGDPQGQFKINPDTGDLYINKSLDREKNSNHILTIRATNIAPPY---W 1350

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP-VIAKIKATDADVGANSA--I 187
               A++ V ++D NDN PQF  + Y V V E+   T  P VI K++ TD D    +    
Sbjct: 1351 YGEASVGVQVLDVNDNGPQFKPEVYNVFVPEN---TPPPYVIEKLEVTDPDSDPQNGGPF 1407

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSR--SNTTQLL 244
            ++ I  GN +  F +    G +    T + E+   Y LV+ A+D    P +   +   + 
Sbjct: 1408 KFGIRSGNEKNLFELTE-DGVLKTRVTFNREETAKYELVVWAEDNAKHPEKPIKSFASVF 1466

Query: 245  INIRDVNDN 253
            +++RD NDN
Sbjct: 1467 VHVRDRNDN 1475



 Score = 71.7 bits (168), Expect = 8e-12
 Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 16/174 (9%)

Query: 1185 ITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPAR 1244
            +T    + DG WH +EI     T+ + +D C      A     G+       TR    + 
Sbjct: 1779 VTGGAMLNDGEWHMIEIHRDETTVRVTVDRCR-----ASNISEGV-------TRSEDRSM 1826

Query: 1245 CEIPTETCHR---FLDLTGPLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSY 1300
            CE+      +   FL+L  PLQ+GG+ +    F  ++  DF GCI +   + +  DL S 
Sbjct: 1827 CEVVGHMKKKKLKFLNLNDPLQLGGIASRDLLFPDLRFHDFNGCIRNLINEGRLYDLKSP 1886

Query: 1301 VADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
               N T  GC      C+   C+  A C    + ++C+C  G  G  C  +T P
Sbjct: 1887 SRQNNTREGCATMDQHCNPNSCHEQATCIGSLNGHVCECNMGRHGDTCKHTTQP 1940



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 44/153 (28%), Positives = 66/153 (43%), Gaps = 21/153 (13%)

Query: 1416 ATLSDGAWHRIEIKWLGTDISVTVDY----------------GLRTVLMPMLANKIQGQY 1459
            A L+DG WH IEI    T + VTVD                  +  V+  M   K++   
Sbjct: 1783 AMLNDGEWHMIEIHRDETTVRVTVDRCRASNISEGVTRSEDRSMCEVVGHMKKKKLKFLN 1842

Query: 1460 IGKIL-IGGLDTTAGLLASDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRAD 1516
            +   L +GG+  +  LL  D+ F  F GCI+++        L  P+ + N R+GC +   
Sbjct: 1843 LNDPLQLGGI-ASRDLLFPDLRFHDFNGCIRNLINEGRLYDLKSPSRQNNTREGCATMDQ 1901

Query: 1517 -CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548
             C  + C   + C+ S +   C C  GR G  C
Sbjct: 1902 HCNPNSCHEQATCIGSLNGHVCECNMGRHGDTC 1934



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 48/224 (21%), Positives = 92/224 (41%), Gaps = 26/224 (11%)

Query: 1123 RRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLR-FSFSLGGG 1181
            R  RI L+++  T+  +G +L +    E+ ++  L+LV  +  R     +  ++F+ G  
Sbjct: 1962 RETRIDLRVR--TRDLNGGVLLHSEGTEKGEYSTLQLVPMKDQRKREILIVVYAFNTGDR 2019

Query: 1182 KSEITVEG-NVGDGSWHTVEIEYFNR--TITMILDDCDKVLSLAGAADFGLKYACANFTR 1238
             +E+     NVGDG W ++ +  +    T+T+  D  + + + +   +  L       T 
Sbjct: 2020 GAEVRASDVNVGDGKWCSIRVNRYRNAATLTVEKDGVNYIRTRSTRGNHSLIMLDPIMTF 2079

Query: 1239 KVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISD-----FYIDHK 1293
                 R    + T  R              N  +S   ++ DF+GCI D     + + H 
Sbjct: 2080 VGGLPRVVHASVTTRRLRRR----------NRSTS---RDNDFIGCIDDLRFHGYRLHHN 2126

Query: 1294 FIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYIC 1337
                 +     G + GC  + + C ++PC     C D W  ++C
Sbjct: 2127 GTKAFATAISKGVVEGC--ESNSCLASPCPTFQWCYDAWRMHVC 2168



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 6/61 (9%)

Query: 1482 FEGCIQDVRIGTAQSLLN-----RPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSST 1536
            F GCI D+R    +   N        + + V +GC+S + C+ S CP +  C  +W    
Sbjct: 2109 FIGCIDDLRFHGYRLHHNGTKAFATAISKGVVEGCESNS-CLASPCPTFQWCYDAWRMHV 2167

Query: 1537 C 1537
            C
Sbjct: 2168 C 2168


>SB_28228| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 838

 Score =  227 bits (554), Expect = 1e-58
 Identities = 217/793 (27%), Positives = 351/793 (44%), Gaps = 81/793 (10%)

Query: 28  YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87
           Y+  VRE    G  +    A D D G NA V Y+I       +N ED+            
Sbjct: 3   YKVFVRENLQGGHVIGQFAARDPDKGANARVTYSI-------INFEDSRS---------D 46

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           ++F I   +G L   ++LDRE ++R+ + ++A D   P   R+S  A I + + D ND+ 
Sbjct: 47  NLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVP---RMSGLAQIVIIVDDVNDHA 103

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P+FS  ++ V +   ++   +  + + +A D D G N  +RY+II GN Q  FSI+ + G
Sbjct: 104 PRFSSGSFHVEI--PLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDG 161

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            + L + L    +    + I+A+D G P RS+T  + I I  V    P+F +S F  +V+
Sbjct: 162 SLFLDEKL--TTLEPIDIKIQARDMGQPERSSTADIRIFIH-VQAGPPQFLSSPFVGNVT 218

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN P G  +V + A   D      + Y++   +  GN      + P  GW+ T   LD E
Sbjct: 219 ENEPKGAFVVHISAASLD-----PVMYSIVSGNEAGN----FRLHPGVGWLTTVRPLDNE 269

Query: 328 TQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
            Q++Y+++V A D      +                      G  E  + +D   G+ V+
Sbjct: 270 KQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVM 329

Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            + A DAD  + L Y I     R  FS+   N  G++T  + L    +  Y+  VS +D+
Sbjct: 330 VIDAVDADRSDILSYRIEDEKARRYFSV---NNEGVVTSTRVLR-DLDSPYLFKVSVSDN 385

Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
           G     A     +     Y P  +      S+ E A +GT V  +  T   +  NA+  Y
Sbjct: 386 GKPPMVAQAMARVV-LLKYQP--QQDQQRTSIQESAALGTRVFTL-LTAKPIR-NAR--Y 438

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
           S+ S +        + +F ++P +G +     LD ET+  +  T  AR+    +     D
Sbjct: 439 SIVSPL--------ETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYANID 490

Query: 567 VEISVVDVNDNEPVFKQQ----LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
           V I+V D NDN P F       LY A +  + +  T V  + ATD D  LNG + Y L  
Sbjct: 491 VIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT 550

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
                  F ++  +G I T    D   +  ++L   A D G P   +  +V+++      
Sbjct: 551 NPGSH--FALNAVTGSITTRGRSDL-FLPWYNLTVEAFDLGKPSLVTRAVVNVR---TGQ 604

Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            PP+F      FY+ EN+P G TIG +   D      +++ Y +  G     F L++  G
Sbjct: 605 FPPLFSRKEYAFYVDENTPRGYTIGTV---DAKSFSGSLLEYMVIEGSGHKRFVLDSVTG 661

Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASP------PLWNDVRVEILVTDVNDNAPVMKD 796
                L     LD+E     Y + + A         PL ++  V+I++ D+NDN P  + 
Sbjct: 662 ----RLTLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEADVKIVLRDLNDNPP--EF 715

Query: 797 FQIIFNNYKDCFP 809
           F++   +Y+D  P
Sbjct: 716 FEL---SYRDTLP 725



 Score =  168 bits (409), Expect = 5e-41
 Identities = 204/799 (25%), Positives = 332/799 (41%), Gaps = 95/799 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D NDH+P F    +   +       + V   +A D D G N  V Y+I        
Sbjct: 94  IIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSI-------- 145

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           Q  F I+   G+L     L    +    + ++A D   P     
Sbjct: 146 -----------IQGNKQGYFSINHIDGSLFLDEKLTT--LEPIDIKIQARDMGQP---ER 189

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SSTA I +  I      PQF    +  +V E+        +  I A   D      + Y+
Sbjct: 190 SSTADIRI-FIHVQAGPPQFLSSPFVGNVTEN--EPKGAFVVHISAASLD-----PVMYS 241

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I+ GN    F +    G ++ V+ LD E+   Y++++ A D    +R +  ++++N+ +V
Sbjct: 242 IVSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMD--LKNRVSKVEVIVNVLNV 299

Query: 251 NDNAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           NDN P+F      + + +V ++V +G  ++ + A DAD   +  L+Y + D+       +
Sbjct: 300 NDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDADR--SDILSYRIEDEKARRYFSV 357

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
                  +  V TS ++ R+  + Y   V+ +D G PP  A A                 
Sbjct: 358 ------NNEGVVTSTRVLRDLDSPYLFKVSVSDNGKPPMVAQAMARVVLLKYQP-----Q 406

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Q    + E    GT V TL       + R  Y I       +F +   +G   + V  
Sbjct: 407 QDQQRTSIQESAALGTRVFTLLTAKPIRNAR--YSIVSP-LETKFRVDPYSGD--VRVRS 461

Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFE----NAPYTASVFED 481
            LD++  + +  T  A ++   +D A + + IT  D+N+  P F     N  Y A V  +
Sbjct: 462 GLDYETVKTHRFTAEARNTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVN 521

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               T V  + ATD D  +N  + Y L        + +    F +N  TG+ITT    D 
Sbjct: 522 PIADTRVFTLEATDPDSDLNGIVRYRL--------ITNPGSHFALNAVTGSITTRGRSDL 573

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTS 599
             +  Y LTV A D G PSL     V  +VV+V   +  P+F ++ Y   + E+   G +
Sbjct: 574 -FLPWYNLTVEAFDLGKPSL-----VTRAVVNVRTGQFPPLFSRKEYAFYVDENTPRGYT 627

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE---SVATHDLK 656
           +   G  DA       + Y +      +  FV+D  +G +   + LD E   ++    + 
Sbjct: 628 I---GTVDAKSFSGSLLEYMVIEGSGHK-RFVLDSVTGRLTLPEPLDFERDSNIYLITVS 683

Query: 657 AVAIDGGT-PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
           A   D     P  S   V I + D+ND+PP F        + E++P+GTT+  + A D D
Sbjct: 684 AKETDNSLLRPLKSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLD 743

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIRAASPPL 774
            G N   HY +    +S  FS++   G     + T   LD+E +P   + +V + +  P 
Sbjct: 744 SGVNGQFHYFV----ESQFFSVDPYTG----WITTKRPLDFETNPTHSFLVVAQDSGNPA 795

Query: 775 WN-DVRVEILVTDVNDNAP 792
            N   RV + +T+VNDNAP
Sbjct: 796 RNGTARVIVELTNVNDNAP 814



 Score =  161 bits (391), Expect = 7e-39
 Identities = 126/417 (30%), Positives = 195/417 (46%), Gaps = 34/417 (8%)

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           RY+I+    + +F +D  SGDV +   LDYE V+++R    A++    +      ++I +
Sbjct: 437 RYSIVSP-LETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYANIDVIITV 495

Query: 248 RDVNDNAPRFYTS----LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            D NDN PRF  +    L+   VS N      +  ++A D D  +N  + Y +       
Sbjct: 496 EDSNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT----- 550

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           N      ++  +G + T G+ D      Y L V A D G P   +  T            
Sbjct: 551 NPGSHFALNAVTGSITTRGRSDLFLPW-YNLTVEAFDLGKP---SLVTRAVVNVRTGQFP 606

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
             F   +Y   + E+ P G  + T+ A      + L Y +  G+   RF + S  GR  +
Sbjct: 607 PLFSRKEYAFYVDENTPRGYTIGTVDAKSFS-GSLLEYMVIEGSGHKRFVLDSVTGR--L 663

Query: 424 TVAQPLDFKQERR-YVLTVSATDSGGR-----SDTAMVQINITDANNYAPVFENAPYTAS 477
           T+ +PLDF+++   Y++TVSA ++           A V+I + D N+  P F    Y  +
Sbjct: 664 TLPEPLDFERDSNIYLITVSAKETDNSLLRPLKSEADVKIVLRDLNDNPPEFFELSYRDT 723

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + E AP+GTTVL V+A D D G+N Q  Y + S+            F ++P TG ITT +
Sbjct: 724 LPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQF-----------FSVDPYTGWITTKR 772

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            LD ET   +   V A+D G P+ + T  V + + +VNDN P F Q LY   + EDA
Sbjct: 773 PLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVAEDA 829



 Score =  153 bits (372), Expect = 1e-36
 Identities = 169/624 (27%), Positives = 269/624 (43%), Gaps = 58/624 (9%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           FR+    G L T   LD EK +RY ++V A D    + +R+S    I VN+++ NDN P+
Sbjct: 251 FRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMD----LKNRVSKVEVI-VNVLNVNDNKPK 305

Query: 150 FSEKTYTV---SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
           F      +   +V +D++V    ++  I A DAD   +  + Y I     +  FS+++  
Sbjct: 306 FVNIRNGIIEGNVLKDVAVGSRVMV--IDAVDAD--RSDILSYRIEDEKARRYFSVNN-E 360

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
           G V+  + L  +    Y   +   D G P         + +        +  TS+ QES 
Sbjct: 361 GVVTSTRVLR-DLDSPYLFKVSVSDNGKPPMVAQAMARVVLLKYQPQQDQQRTSI-QESA 418

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
           +    + ++++  +        NA   Y++        ++    +DP SG V     LD 
Sbjct: 419 ALGTRV-FTLLTAKPIR-----NAR--YSIVSP-----LETKFRVDPYSGDVRVRSGLDY 465

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP----GQYEVELAEDEPPG 382
           ET   ++    A +  D    A                 F      G Y   ++ +    
Sbjct: 466 ETVKTHRFTAEARNTRDNTDYANIDVIITVEDSNDNRPRFTMNKTNGLYLAYVSVNPIAD 525

Query: 383 TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           T V TL ATD D D    + Y +   N    F++ +  G   IT     D      Y LT
Sbjct: 526 TRVFTLEATDPDSDLNGIVRYRLIT-NPGSHFALNAVTGS--ITTRGRSDLFLPW-YNLT 581

Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           V A D G  S      +N+     + P+F    Y   V E+ P G T+  V A       
Sbjct: 582 VEAFDLGKPSLVTRAVVNVR-TGQFPPLFSRKEYAFYVDENTPRGYTIGTVDAKS----- 635

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGG-- 557
               + SL   +  E   H  ++FV++  TG +T  + LD E  S  YL+TV+A++    
Sbjct: 636 ---FSGSLLEYMVIEGSGH--KRFVLDSVTGRLTLPEPLDFERDSNIYLITVSAKETDNS 690

Query: 558 -VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            +  L    DV+I + D+NDN P F +  Y   + E A VGT+V  V A D D G+NG+ 
Sbjct: 691 LLRPLKSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQF 750

Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
           HY +     E   F +DP +G I T + LD E+  TH    VA D G P ++ T  V ++
Sbjct: 751 HYFV-----ESQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVE 805

Query: 677 IEDINDSPPVFESDCLTFYISENS 700
           + ++ND+ P F       +++E++
Sbjct: 806 LTNVNDNAPRFSQSLYNVFVAEDA 829



 Score =  140 bits (339), Expect = 1e-32
 Identities = 159/610 (26%), Positives = 273/610 (44%), Gaps = 65/610 (10%)

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
           +++  V EN+  G+ I +  A D D+G NA +TY++ + + + + +L  +I P +G +  
Sbjct: 2   VYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNL-FSIHPFTGVLTA 60

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
              LDRE  +++ L + A D G P  S  A               F  G + VE+  + P
Sbjct: 61  LSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTP 120

Query: 381 PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR----GLITVAQPLDFKQE 434
           P + V    A D D   +  + Y I  GN +G FSI   +G       +T  +P+D K  
Sbjct: 121 PDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIK-- 178

Query: 435 RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
                 + A D G   RS TA ++I I       P F ++P+  +V E+ P G  V+ +S
Sbjct: 179 ------IQARDMGQPERSSTADIRIFI-HVQAGPPQFLSSPFVGNVTENEPKGAFVVHIS 231

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
           A   D      + YS+ S   NEA       F ++P  G +TT + LD E  S Y + V 
Sbjct: 232 AASLD-----PVMYSIVS--GNEA-----GNFRLHPGVGWLTTVRPLDNEKQSRYKIIVM 279

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANIMEDALVGTSVSQVGATDAD 609
           A D  + +     +V ++V++VNDN+P F   +  +   N+++D  VG+ V  + A DAD
Sbjct: 280 AMD--LKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDAD 337

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
              +  + Y ++  D +   +      GV+ + + L R+  + +  K    D G PP  +
Sbjct: 338 --RSDILSYRIE--DEKARRYFSVNNEGVVTSTRVL-RDLDSPYLFKVSVSDNGKPPMVA 392

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             +  + +  +   P   + D     I E++ +GT +  +    P    NA   YSI   
Sbjct: 393 QAMARVVL--LKYQP---QQDQQRTSIQESAALGTRVFTLLTAKPIR--NA--RYSIVSP 443

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVT--D 786
            ++  F ++   G    ++     LDYE+  K +     A +     D   +++++T  D
Sbjct: 444 LET-KFRVDPYSG----DVRVRSGLDYETV-KTHRFTAEARNTRDNTDYANIDVIITVED 497

Query: 787 VNDNAP--VMKDFQIIFNNYKDCFPVGPFG----RVPAYDADVTDKLQYRILSGNNANLI 840
            NDN P   M     ++  Y    P+             D+D+   ++YR+++ N  +  
Sbjct: 498 SNDNRPRFTMNKTNGLYLAYVSVNPIADTRVFTLEATDPDSDLNGIVRYRLIT-NPGSHF 556

Query: 841 LLNETTGSMT 850
            LN  TGS+T
Sbjct: 557 ALNAVTGSIT 566



 Score = 98.3 bits (234), Expect = 8e-20
 Identities = 83/305 (27%), Positives = 133/305 (43%), Gaps = 17/305 (5%)

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTN 642
           +Y   + E+   G  + Q  A D D G N R+ Y +      R +  F I P +GV+   
Sbjct: 2   VYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTAL 61

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
             LDRE ++ H L   A D G P  S    + I ++D+ND  P F S      I  N+P 
Sbjct: 62  STLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPP 121

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS--DKAELVTMVDLDYESPR 760
            + + + RA DPD G N +V YSI  G+    FS+    GS     +L T+  +D +   
Sbjct: 122 DSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIKIQA 181

Query: 761 KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
           +      R+++     D+R+ I    V    P       +  N  +  P G F  V    
Sbjct: 182 RDMGQPERSSTA----DIRIFI---HVQAGPPQFLSSPFV-GNVTENEPKGAF--VVHIS 231

Query: 821 ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP---KLATMEVSVTDGVNEIK 877
           A   D + Y I+SGN A    L+   G +T    L+       K+  M + + + V++++
Sbjct: 232 AASLDPVMYSIVSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMDLKNRVSKVE 291

Query: 878 AMMQL 882
            ++ +
Sbjct: 292 VIVNV 296



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 47/153 (30%), Positives = 69/153 (45%), Gaps = 26/153 (16%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I + D ND+ P F    Y  ++ E A  GTTVL++ A D D G N +  Y +E      
Sbjct: 702 KIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVE------ 755

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               F +D  +G + T+  LD E    ++ LV A D  +P    
Sbjct: 756 -----------------SQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPAR-- 796

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
            + TA + V + + NDN P+FS+  Y V V ED
Sbjct: 797 -NGTARVIVELTNVNDNAPRFSQSLYNVFVAED 828


>SB_27857| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 2418

 Score =  221 bits (539), Expect = 9e-57
 Identities = 216/804 (26%), Positives = 348/804 (43%), Gaps = 79/804 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++NV D ND +PVFE  QY  ++ E     T+VL ++ATD+D G N  + Y ++      
Sbjct: 237 RVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMK------ 290

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            NP             V   F ID  +G +    +LD     ++T+ + A D+  P   R
Sbjct: 291 -NP-------------VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDP--PR 334

Query: 130 LSSTATIHVNI------------IDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
            S+ AT+ +++             D  +N  P F +  YT S+ ED        +  ++A
Sbjct: 335 TSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFP--PKGALLVMRA 392

Query: 177 TDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQDG 232
            D D +G N  +RY++  GN   +F+ID  SG V+L  ++DYE   +   Y L + A D 
Sbjct: 393 ADNDPIGPNKRLRYSL-SGNGVSKFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQ 451

Query: 233 GSPSRSNTTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           G  S S TTQLLI I+DV  N N+PRF        +SEN+     +  V A D+D   N 
Sbjct: 452 GPGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNP 511

Query: 291 ELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSA 348
                       G   L +  +D  +G V  +   LDRE  ++Y L+V A+D    PRS+
Sbjct: 512 SSPDGKVVYSIVGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSS 571

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
                            F    Y  ++ E++P GT V  +   DADE     Y +    T
Sbjct: 572 RLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPSYTVI---T 628

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN--NYA 466
            G      +   G+I  ++ LD  +     L V    S   S TA  Q+NIT  +  N  
Sbjct: 629 PG-VPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRP 687

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           PVF+N PY+  V E+      +  ++A DS   ++  + Y+L+           D  F +
Sbjct: 688 PVFKNTPYSVKVPEEMGPLPNLFCIAAVDS---LSRPVQYTLAPGA--------DGLFEV 736

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           +  +G + T    + E +  Y L + AR   V  ++ +  + + V +  D  P F    Y
Sbjct: 737 DKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEVA-SASLTVEVTEEKD-LPKFSSDSY 794

Query: 587 TANIMEDALVGTSVSQ-VGATDADVGLNG-RIHYELDPKDREEGSFVIDPASG----VIR 640
              + E A  GT+++  +   D+D   +      E         +F +   SG     ++
Sbjct: 795 QLTVDESAAPGTTLAPGLLIIDSDTSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQ 854

Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
               LD    + +     A D       +T  V + + D+ND  P F  +     +  ++
Sbjct: 855 AGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSST 914

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
           P G+++  ++A D D G NA V Y +   ++S  F L     +D  +L T   L   +P 
Sbjct: 915 PAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFIL-----NDNNQLSTASTL---TPN 966

Query: 761 KKYELVIRAASPPLWNDVRVEILV 784
            +Y+L+IRA+     N    ++ V
Sbjct: 967 VRYQLLIRASDSATRNPSSAQVPV 990



 Score =  218 bits (533), Expect = 5e-56
 Identities = 209/702 (29%), Positives = 319/702 (45%), Gaps = 69/702 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND+ P++  ++  A V   + +G  V  L+A D+D G +  V Y ++  + D 
Sbjct: 1741 EVVVLDVNDNRPIWMERERLARVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSPSNDA 1800

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                 +           Q  F I+ ++  +    SL   K  RY + V A D   P   R
Sbjct: 1801 KRKRRSPP---------QHPFTINPKTRQMEVAGSL---KDQRYDLDVFAFDYGIP---R 1845

Query: 130  LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            L+S T T++V+        P+FS+ +Y   V ED       ++  I A     GA   + 
Sbjct: 1846 LTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLS--LVGIILARSIS-GAR--LD 1900

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINI 247
            Y I+ GN   +F I    G + L   LD+E+ ++ Y L ++A +       +T  + I++
Sbjct: 1901 YKIVSGNVGDKF-IAMGDGRILLNSLLDFERDQTQYNLKVKATEQIPDGLDSTVDVKIDV 1959

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-----LTYTMTDKDYT 302
             + ND+ P F   L+   + E+  +G  +  V A D D   +       LTY++      
Sbjct: 1960 INANDHFPYFDQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQ 2019

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            G       IDP +G +  S  LD E Q  + L V ATD G                    
Sbjct: 2020 GG---KFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDN 2076

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F+   YE  +AE    G  +  + A DAD D  + Y   GG  +  FS+    G  +
Sbjct: 2077 RPTFLKSAYEFRVAEGAATGESLAIVVAVDADGD-AVTYSKAGGALQ--FSVDQSTG--V 2131

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            IT+   LD   + +Y L V A DSGG + T  V  N+ DANN  P F N   T S+ E+ 
Sbjct: 2132 ITLNSALD-PNKNQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQFTNCG-TVSIREND 2189

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P  T +  ++ATD+D G N QITYS+  + S++ +      F I P+TG + +   LDRE
Sbjct: 2190 PRDTKITQLTATDADRGQNGQITYSIE-DASSQTL------FSIEPRTGVVRSLTSLDRE 2242

Query: 543  TMSGYLLTVTARDGGVPSLSDTTD-------VEISVVDVNDNEPVFKQQLYTANIMEDAL 595
                Y   + A DG   S  D ++       + I+V DVNDN P F    Y  ++   A 
Sbjct: 2243 NKDSYNAIIKAEDGS--SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAP 2300

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN---KALDRES--- 649
             G+++  V ATDAD G N +I Y L   D   G F +D +SG++RTN     L  E+   
Sbjct: 2301 NGSNILTVQATDADSGSNAKIKYAL--LDSAGGLFRLD-SSGILRTNTNPARLQLETGKK 2357

Query: 650  ----VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
                V+  D++++A  G  P + +     I+I   N+ PP F
Sbjct: 2358 LLLEVSAKDVESIA--GTQPGKPTKYTTQIEILVSNEEPPKF 2397



 Score =  216 bits (528), Expect = 2e-55
 Identities = 248/898 (27%), Positives = 389/898 (43%), Gaps = 94/898 (10%)

Query: 10  QINVLDCNDHSPVFEMQQ---YEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIE 63
           +I +LD N+  PVF++ Q   YE  V+EG +  T V  L+   ATD+D   +    Y+I 
Sbjct: 116 RITILDVNNFHPVFQLSQGEHYEGFVKEGTAENTIVEGLEQCHATDRD--TSGIRGYSI- 172

Query: 64  LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALL--TRASLDREKVARYTVL-VKAT 120
                                 VQ    +  R   +L  T   + R+    Y +L V+ T
Sbjct: 173 ---------ISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDNNPYIMLTVQVT 223

Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
           D  +P     S TA I VN+ D ND  P F    Y  ++ E+  +  +  + +++ATD D
Sbjct: 224 DGGNPSH---SGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTS--VLRVRATDKD 278

Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN- 239
            G N  I Y  +       F+ID+++G + + KTLDY     + L I A+D G P R++ 
Sbjct: 279 DGTNGGI-YYYMKNPVNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDPPRTSA 337

Query: 240 --TTQLLI--NIR--------DVNDNA-PRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
             T ++ +  NI+        D  +N  P F  S +  S+ E+ P   +++ ++A D D 
Sbjct: 338 EATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFPPKGALLVMRAADNDP 397

Query: 287 -GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK---YQLLVTATDGG 342
            G N  L Y++     +GN      IDP SG V  +  +D E       Y L VTATD G
Sbjct: 398 IGPNKRLRYSL-----SGNGVSKFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQG 452

Query: 343 DPPRSATATXXXXXXXXXXXXXX--FMPGQYEVELAEDEPPGTPVVTLTATDADE----- 395
               SAT                  F P Q  +E++E+    + V T++ATD+D      
Sbjct: 453 PGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNPS 512

Query: 396 --DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSG--GRS 450
             D ++ Y I GG   G F + S  G   + VA P LD +   +Y L V A+D+    RS
Sbjct: 513 SPDGKVVYSIVGGTGLGVFRVDSNTGE--VKVAVPSLDREGTSQYTLVVKASDNATFPRS 570

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
               + IN+ D ++  P F    Y A V E+ P GT V VV   D+D G N   T     
Sbjct: 571 SRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPSYT----- 625

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
                 V      + I P TG I T+K LD+  +S   L V  R     S +    V I+
Sbjct: 626 ------VITPGVPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNIT 679

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           V+   +  PVFK   Y+  + E+     ++  + A D+   L+  + Y L P    +G F
Sbjct: 680 VISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAAVDS---LSRPVQYTLAP--GADGLF 734

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            +D  SG + T  + + E+V  ++L+  A        +S  +  +++ +  D P  F SD
Sbjct: 735 EVDKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEVASASLT-VEVTEEKDLPK-FSSD 792

Query: 691 CLTFYISENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAEL 748
                + E++  GTT+   +   D D   +     S++     ++ ++ E  Q S +  L
Sbjct: 793 SYQLTVDESAAPGTTLAPGLLIIDSDTSSDQ-FDCSMEAITSLHTLYNFEVTQQSGRCFL 851

Query: 749 VTMVDLDYESP-RKKYELVIRAASPPLWN---DVRVEILVTDVNDNAPVMKDFQIIFNNY 804
                   ++    KY   +RA      N     +VE+ V DVND+ P     +  + + 
Sbjct: 852 RVQAGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQ-ESYWLSV 910

Query: 805 KDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859
               P G     V A D D+    +++Y +L   N+   +LN+     T S  L  NV
Sbjct: 911 PSSTPAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFILNDNNQLSTAS-TLTPNV 967



 Score =  212 bits (517), Expect = 4e-54
 Identities = 208/795 (26%), Positives = 352/795 (44%), Gaps = 78/795 (9%)

Query: 21   PVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADTLNPEDAXXXX 79
            P F   +Y  S+RE       +L ++A D D IG N  + Y++   + + ++        
Sbjct: 366  PYFPQSRYTFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSL---SGNGVSK------- 415

Query: 80   XXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSSTATI 136
                      F ID  SG +    S+D E       Y + V ATDQ  P S   ++   I
Sbjct: 416  ----------FAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQG-PGSLSATTQLLI 464

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA----IRYAI 191
             +  +D+N N P+F  +   + + E++    N ++  + ATD+D VG  S+    + Y+I
Sbjct: 465  EIQDVDENKNSPRFDPQQAILEISENLK--QNSLVTTVSATDSDSVGNPSSPDGKVVYSI 522

Query: 192  IGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +GG     F +DS +G+V + V +LD E    Y LV++A D  +  RS+   L+IN+ D 
Sbjct: 523  VGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDE 582

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            +DN P F   ++   V EN P G  +  V   DADEG N   +YT+          +P  
Sbjct: 583  DDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNP--SYTVITPG------VPYK 634

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+P +G + TS  LD+   +  +L V         ++A                 F    
Sbjct: 635  IEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTP 694

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y V++ E+  P   +  + A D+     + Y +  G   G F +   +GR  +      +
Sbjct: 695  YSVKVPEEMGPLPNLFCIAAVDS-LSRPVQYTLAPG-ADGLFEVDKDSGR--LHTKNSFN 750

Query: 431  FKQERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            ++   RY L + A T S     +A + + +T+  +  P F +  Y  +V E A  GTT+ 
Sbjct: 751  YENVDRYNLRIEARTSSVQEVASASLTVEVTEEKDL-PKFSSDSYQLTVDESAAPGTTLA 809

Query: 490  V-VSATDSDVGINAQITYSLSSEISNEAVA--HHDQQFVINPQTGA----ITTNKLLDRE 542
              +   DSD       T S   + S EA+   H    F +  Q+G     +     LD  
Sbjct: 810  PGLLIIDSD-------TSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQAGGKLDAH 862

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              S Y   V A D    ++  T  VE++V+DVND++P F Q+ Y  ++      G+S+  
Sbjct: 863  LASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVT 922

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A D D+G N ++ YEL  ++  E  F+++  +  + T   L       + L   A D 
Sbjct: 923  VQAEDMDIGTNAQVRYELLRQENSE-RFILND-NNQLSTASTLTPN--VRYQLLIRASDS 978

Query: 663  GT-PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             T  P S+ V V++ +   ++SP VF+       + E+S   T +   +A        + 
Sbjct: 979  ATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLPEDSSANTLVFTAKATRSGSSRGSR 1038

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASPPLWND 777
             + S+ G      FS++     D  ++  +  LD+E+ +  + + +RA     +  L ++
Sbjct: 1039 TNSSVIG---EAMFSIK----PDTGQVYLIKKLDFET-KSYFPIAVRAKYSGGAIELASE 1090

Query: 778  VRVEILVTDVNDNAP 792
            V  ++ + DVNDN P
Sbjct: 1091 VVAKVTIVDVNDNGP 1105



 Score =  210 bits (513), Expect = 1e-53
 Identities = 192/633 (30%), Positives = 289/633 (45%), Gaps = 45/633 (7%)

Query: 326  RETQ-AKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            R TQ + Y ++V ATDG  D  +                   F    Y   + E    G 
Sbjct: 1106 RYTQGSSYIIIVVATDGATDGSQKIQKYTVNVQVLDTPRPPSFPQKTYSAPVTETAGVGD 1165

Query: 384  PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
             V T+ A  +  +  L Y    GN    F +   NG G+I+VA+ LD ++   Y L +  
Sbjct: 1166 TVTTVRAVYSKPNAFLKYTFVSGNEDNTFCV---NGFGIISVAKSLDREKVAGYTLGMRV 1222

Query: 444  TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINA 502
            T  G   D   V +N+TD N+ AP F +A Y  S+ E     T +L  V A D D G N 
Sbjct: 1223 T-LGQHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNG 1281

Query: 503  QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-L 561
            +I YS+ S +  +     D+ F I+  TG ITT   LD ET   + L + A D G P  L
Sbjct: 1282 KILYSILSGVHPD----WDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSPKRL 1337

Query: 562  SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
            S    V+I V+D NDN PVF    Y A I   A+ GTSV QV ATD D G NG+I Y + 
Sbjct: 1338 SGIAQVDIDVIDRNDNSPVFAAAFYRAKISLGAVKGTSVLQVHATDLDSGQNGQITYSI- 1396

Query: 622  PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
             +  EE +F I+   GVI  +K+L   +     LK  A D    P+S +V V I +  + 
Sbjct: 1397 IQGNEEEAFTIN-EQGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVY-LP 1454

Query: 682  DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
            D PP+F    +T Y+ E  P    +  ++A       +  + Y++  G+++  F +    
Sbjct: 1455 DGPPMFVVSPVTVYVKEGVPANHRVAGVKA-----ATSEALTYTLLSGNEAGMFRINPST 1509

Query: 742  GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTDVNDNAPVMKDF--- 797
            GS    L    +LDYE  R++YEL I A      +  V + I+V ++NDN P   D    
Sbjct: 1510 GS----LDATRELDYEE-RRRYELKIEARDTRDRSAMVELIIIVVNINDNKPTFVDIVDG 1564

Query: 798  QIIFNNYKDCFPVG-----PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852
            QI       C P          R+ A+D D  D++ + I+  +  +L  + ++ G +T  
Sbjct: 1565 QIDRKAIGTCSPTDIAEGEVITRLGAFDRD-GDEITF-IVPDDVKDLFKI-DSRGVVTAK 1621

Query: 853  PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLN---DMTAEQFL 909
              +  ++PK+    V   D   E      + VRL+      +   VR+N   D      +
Sbjct: 1622 KPIE-DLPKIYPFNVKALDN-GEPPQETDVKVRLVFVHYRPDQKHVRVNVREDTPTGSVI 1679

Query: 910  SPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDV 942
            + +  +F +G+ +++   K N   FSV+ + DV
Sbjct: 1680 ATVRRYFPNGIVSLLLPEKAN---FSVRANGDV 1709



 Score =  208 bits (507), Expect = 6e-53
 Identities = 217/817 (26%), Positives = 368/817 (45%), Gaps = 89/817 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V   ++   VF+   Y  ++ E +S+ T V T KAT     + +    ++      ++
Sbjct: 992  VSVYSPSESPIVFDKSSYNQNLPEDSSANTLVFTAKATRSGSSRGSRTNSSVIGEAMFSI 1051

Query: 71   NPEDAXXXXXXXXXX-VQDVFRIDGR---SGALLTRASLDREKVA---------RYT--- 114
             P+              +  F I  R   SG  +  AS    KV          RYT   
Sbjct: 1052 KPDTGQVYLIKKLDFETKSYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRYTQGS 1111

Query: 115  ---VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171
               ++V ATD A+  S ++    T++V ++D     P F +KTY+  V E   V D   +
Sbjct: 1112 SYIIIVVATDGATDGSQKIQKY-TVNVQVLD-TPRPPSFPQKTYSAPVTETAGVGDT--V 1167

Query: 172  AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
              ++A  +    N+ ++Y  + GN    F ++   G +S+ K+LD E+V  Y L +R   
Sbjct: 1168 TTVRAVYSK--PNAFLKYTFVSGNEDNTFCVNGF-GIISVAKSLDREKVAGYTLGMRVTL 1224

Query: 232  GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDADEGVNA 290
            G      + T + +N+ D+ND+AP F +++++ S+ E +     I+  V A D D G N 
Sbjct: 1225 G---QHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNG 1281

Query: 291  ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SAT 349
            ++ Y++    +  + D    ID  +G + T   LD ET   + L + A D G P R S  
Sbjct: 1282 KILYSILSGVHP-DWDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSPKRLSGI 1340

Query: 350  ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407
            A               F    Y  +++     GT V+ + ATD D  ++ ++ Y I  GN
Sbjct: 1341 AQVDIDVIDRNDNSPVFAAAFYRAKISLGAVKGTSVLQVHATDLDSGQNGQITYSIIQGN 1400

Query: 408  TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465
                F+I   N +G+I V + L      ++ L V A D     RS +  V+IN+   +  
Sbjct: 1401 EEEAFTI---NEQGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVYLPDG- 1456

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
             P+F  +P T  V E  P    V  V A  S+      +TY+L S   NEA       F 
Sbjct: 1457 PPMFVVSPVTVYVKEGVPANHRVAGVKAATSEA-----LTYTLLS--GNEA-----GMFR 1504

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---- 581
            INP TG++   + LD E    Y L + ARD      S   ++ I VV++NDN+P F    
Sbjct: 1505 INPSTGSLDATRELDYEERRRYELKIEARD--TRDRSAMVELIIIVVNINDNKPTFVDIV 1562

Query: 582  -----KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636
                 ++ + T +   D   G  ++++GA D D      I + + P D ++  F ID + 
Sbjct: 1563 DGQIDRKAIGTCS-PTDIAEGEVITRLGAFDRD---GDEITF-IVPDDVKD-LFKID-SR 1615

Query: 637  GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
            GV+   K ++ +    +     A+D G PPQ +   V +++  ++  P   +   +   +
Sbjct: 1616 GVVTAKKPIE-DLPKIYPFNVKALDNGEPPQETD--VKVRLVFVHYRP---DQKHVRVNV 1669

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
             E++P G+ I  +R +     PN +V   +    +  +FS+         +++ +  LDY
Sbjct: 1670 REDTPTGSVIATVRRY----FPNGIVSLLL---PEKANFSVRA-----NGDVILLTPLDY 1717

Query: 757  ESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793
            ES ++ + + +R       NDV VE++V DVNDN P+
Sbjct: 1718 ES-QQFHRMTVREELGNQTNDVDVEVVVLDVNDNRPI 1753



 Score =  205 bits (500), Expect = 5e-52
 Identities = 202/718 (28%), Positives = 332/718 (46%), Gaps = 79/718 (11%)

Query: 125 PVSDRLSSTA-TIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDAD 180
           P  + L   A T+ + I+D N+ +P F     + Y   V E     +N ++  ++   A 
Sbjct: 103 PRGETLGGIAITLRITILDVNNFHPVFQLSQGEHYEGFVKE--GTAENTIVEGLEQCHAT 160

Query: 181 VGANSAIR-YAIIGGNTQMQFSIDSL---SGDVS----LVKTLDYEQVRS-----YRLVI 227
               S IR Y+II GN +  F ++++   SG  S    ++KT     VR        L +
Sbjct: 161 DRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDNNPYIMLTV 220

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287
           +  DGG+PS S T  + +N+ D ND  P F +S ++E+++EN PI  S++RV+A D D+G
Sbjct: 221 QVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDG 280

Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR- 346
            N  + Y M +      V+   TID  +G +  +  LD   + K+ L ++A D GDPPR 
Sbjct: 281 TNGGIYYYMKNP-----VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDPPRT 335

Query: 347 SATATXX-------------XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
           SA AT                           F   +Y   + ED PP   ++ + A D 
Sbjct: 336 SAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFPPKGALLVMRAADN 395

Query: 394 D---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSG 447
           D    + RL Y ++ GN   +F+I  ++  G++T+   +D++       Y LTV+ATD G
Sbjct: 396 DPIGPNKRLRYSLS-GNGVSKFAIDPES--GVVTLTDSVDYENTPNNHVYDLTVTATDQG 452

Query: 448 GRSDTA----MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VG--- 499
             S +A    +++I   D N  +P F+       + E+    + V  VSATDSD VG   
Sbjct: 453 PGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNPS 512

Query: 500 -INAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGG 557
             + ++ YS+   +    +      F ++  TG +      LDRE  S Y L V A D  
Sbjct: 513 SPDGKVVYSI---VGGTGLG----VFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNA 565

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
               S    + I+++D +DN P F Q +Y A + E+   GT V+ V   DAD G N   +
Sbjct: 566 TFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPS-Y 624

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
             + P       + I+P++GVIRT+K+LD+  ++T +L+ +        +++   V+I +
Sbjct: 625 TVITP----GVPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITV 680

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
               + PPVF++   +  + E       +  I A D    P   V Y++  G D   F +
Sbjct: 681 ISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAAVDSLSRP---VQYTLAPGAD-GLFEV 736

Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795
           +     D   L T    +YE+   +Y L I A +  +  +V    L  +V +   + K
Sbjct: 737 D----KDSGRLHTKNSFNYENV-DRYNLRIEARTSSV-QEVASASLTVEVTEEKDLPK 788



 Score =  204 bits (499), Expect = 6e-52
 Identities = 230/886 (25%), Positives = 373/886 (42%), Gaps = 72/886 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTAD 68
            +I   D  D S + E+     ++ +   +   ++  +   + IG  +  +    E++T  
Sbjct: 1529 KIEARDTRDRSAMVELIIIVVNINDNKPTFVDIVDGQIDRKAIGTCSPTDIAEGEVITRL 1588

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
                 D           V+D+F+ID R      +   D  K+  Y   VKA D   P  +
Sbjct: 1589 GAFDRDGDEITFIVPDDVKDLFKIDSRGVVTAKKPIEDLPKI--YPFNVKALDNGEPPQE 1646

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
                   + V+   D        +K   V+V ED       VIA ++        N  + 
Sbjct: 1647 TDVKVRLVFVHYRPD--------QKHVRVNVREDTPT--GSVIATVRR----YFPNGIVS 1692

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
              +     +  FS+ + +GDV L+  LDYE  + +R+ +R + G   +++N   + + + 
Sbjct: 1693 LLL---PEKANFSVRA-NGDVILLTPLDYESQQFHRMTVREELG---NQTNDVDVEVVVL 1745

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN---- 304
            DVNDN P +        V+ N   G  + +++A D D+G +  + Y +            
Sbjct: 1746 DVNDNRPIWMERERLARVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSPSNDAKRKRR 1805

Query: 305  --VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXX 361
                 P TI+P++  +  +G L  +   +Y L V A D G P   S T T          
Sbjct: 1806 SPPQHPFTINPKTRQMEVAGSLKDQ---RYDLDVFAFDYGIPRLTSDTITLNVDGSAAGQ 1862

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F    Y   ++ED    + V  + A       RL Y+I  GN   +F      G G
Sbjct: 1863 LPPRFSKVSYHFMVSEDAKYLSLVGIILARSIS-GARLDYKIVSGNVGDKFIAM---GDG 1918

Query: 422  LITVAQPLDFKQER-RYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASV 478
             I +   LDF++++ +Y L V AT+    G   T  V+I++ +AN++ P F+   Y+  +
Sbjct: 1919 RILLNSLLDFERDQTQYNLKVKATEQIPDGLDSTVDVKIDVINANDHFPYFDQQLYSVQI 1978

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E   +G  V  V+A D D   +   +    +  S E       +F I+P TG I+ +  
Sbjct: 1979 PESTAVGVLVQEVTAKDCDCLSSCTCSPGFLT-YSIEPSKEQGGKFYIDPATGKISVSVA 2037

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LD E    +LL V A D G  S      V +++ +VNDN P F +  Y   + E A  G 
Sbjct: 2038 LDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAYEFRVAEGAATGE 2097

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            S++ V A DAD      + Y    K      F +D ++GVI  N ALD      + L+ +
Sbjct: 2098 SLAIVVAVDAD---GDAVTYS---KAGGALQFSVDQSTGVITLNSALDPNK-NQYTLQVM 2150

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A D G    +STV V   + D N++ P F ++C T  I EN P  T I ++ A D D G 
Sbjct: 2151 AKDSGG--LTSTVSVTFNVADANNNVPQF-TNCGTVSIRENDPRDTKITQLTATDADRGQ 2207

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
            N  + YSI+       FS+E R G  +    ++  LD E+ +  Y  +I+A       D 
Sbjct: 2208 NGQITYSIEDASSQTLFSIEPRTGVVR----SLTSLDREN-KDSYNAIIKAEDGSSKQDE 2262

Query: 779  RVEIL--------VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQ 828
               +L        V DVNDN P     +   + +           V A DAD     K++
Sbjct: 2263 SERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAPNGSNILTVQATDADSGSNAKIK 2322

Query: 829  YRILSGNNANLILLNETTGSM---TLSPQLNTNVPKLATMEVSVTD 871
            Y +L  ++A  +   +++G +   T   +L     K   +EVS  D
Sbjct: 2323 YALL--DSAGGLFRLDSSGILRTNTNPARLQLETGKKLLLEVSAKD 2366



 Score =  194 bits (474), Expect = 6e-49
 Identities = 230/908 (25%), Positives = 386/908 (42%), Gaps = 104/908 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69
            +N+ D ND +P F    Y  S++EG +  T +L  + A D D G N ++ Y+I       
Sbjct: 1235 VNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNGKILYSI----LSG 1290

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            ++P+                F ID  +G + T+ +LD E    +T+ ++A D  SP   R
Sbjct: 1291 VHPD------------WDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSP--KR 1336

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LS  A + +++ID NDN P F+   Y   +   +       + ++ ATD D G N  I Y
Sbjct: 1337 LSGIAQVDIDVIDRNDNSPVFAAAFYRAKIS--LGAVKGTSVLQVHATDLDSGQNGQITY 1394

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +II GN +  F+I+   G + + K+L       + L + A+D  +  RS +  + IN+  
Sbjct: 1395 SIIQGNEEEAFTINE-QGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVY- 1452

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            + D  P F  S     V E VP  + +  V+A  ++      LTYT+     +GN     
Sbjct: 1453 LPDGPPMFVVSPVTVYVKEGVPANHRVAGVKAATSEA-----LTYTLL----SGNEAGMF 1503

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP- 368
             I+P +G +  + +LD E + +Y+L + A D  D  RSA                 F+  
Sbjct: 1504 RINPSTGSLDATRELDYEERRRYELKIEARDTRD--RSAMVELIIIVVNINDNKPTFVDI 1561

Query: 369  --GQYEVELA-----EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
              GQ + +        D   G  +  L A D D D      I   + +  F I S   RG
Sbjct: 1562 VDGQIDRKAIGTCSPTDIAEGEVITRLGAFDRDGDEITF--IVPDDVKDLFKIDS---RG 1616

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            ++T  +P++    + Y   V A D+G       V++ +   + Y P  +      +V ED
Sbjct: 1617 VVTAKKPIE-DLPKIYPFNVKALDNGEPPQETDVKVRLVFVH-YRP--DQKHVRVNVRED 1672

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
             P G+ +  V     +      I   L  E +N +V  +    ++ P          LD 
Sbjct: 1673 TPTGSVIATVRRYFPN-----GIVSLLLPEKANFSVRANGDVILLTP----------LDY 1717

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E+   + +TV    G   + ++  DVE+ V+DVNDN P++ ++   A +  ++  G  V 
Sbjct: 1718 ESQQFHRMTVREELG---NQTNDVDVEVVVLDVNDNRPIWMERERLARVNTNSRAGAQVY 1774

Query: 602  QVGATDADVGLNGRIHYEL-----DPKDRE----EGSFVIDPASGVIRTNKALDRESVAT 652
            Q+ A D D G +G + Y+L     D K +     +  F I+P +  +    +L  +    
Sbjct: 1775 QLEARDEDDGSSGLVGYQLKSPSNDAKRKRRSPPQHPFTINPKTRQMEVAGSLKDQ---R 1831

Query: 653  HDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
            +DL   A D G P   S T+ +++        PP F      F +SE++   + +G I A
Sbjct: 1832 YDLDVFAFDYGIPRLTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLSLVGIILA 1891

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
                    A + Y I  G+  + F      G  +  L ++  LD+E  + +Y L ++A  
Sbjct: 1892 RSIS---GARLDYKIVSGNVGDKF---IAMGDGRILLNSL--LDFERDQTQYNLKVKATE 1943

Query: 772  ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK- 826
                 L + V V+I V + ND+ P   D Q+      +   VG     V A D D     
Sbjct: 1944 QIPDGLDSTVDVKIDVINANDHFPYF-DQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSC 2002

Query: 827  ------LQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878
                  L Y I  S        ++  TG +++S  L+    +   ++V  TD G    + 
Sbjct: 2003 TCSPGFLTYSIEPSKEQGGKFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQG 2062

Query: 879  MMQLSVRL 886
            +  ++V L
Sbjct: 2063 LCFVNVTL 2070



 Score =  170 bits (413), Expect = 2e-41
 Identities = 202/754 (26%), Positives = 327/754 (43%), Gaps = 75/754 (9%)

Query: 207 GDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF------- 257
           G V+  + ++YE  +   Y L +  +  G         L I I DVN+  P F       
Sbjct: 77  GHVTSTQEIEYEIGKTNKYDLTVLQRPRGETLGGIAITLRITILDVNNFHPVFQLSQGEH 136

Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDY--TGNVDLPITIDPR 314
           Y    +E  +EN  I   + +  A D D  G+      +  +K Y     V +   +  R
Sbjct: 137 YEGFVKEGTAENT-IVEGLEQCHATDRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSR 195

Query: 315 SGWVY-TSGQ-LDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
              V  T+G+ + R+    Y +L V  TDGG+P  S TA               F   QY
Sbjct: 196 KFLVLKTTGKPIVRDDNNPYIMLTVQVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQY 255

Query: 372 EVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
              +AE+ P  T V+ + ATD D+  N   Y          F+I +    G+I VA+ LD
Sbjct: 256 RETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMKNPVNSYFTIDAIT--GVIRVAKTLD 313

Query: 431 FKQERRYVLTVSATDSGG---RSDTAMVQINITD-------------ANNYAPVFENAPY 474
           +    ++ L +SA D G     S  A V+I++ +               N  P F  + Y
Sbjct: 314 YNARDKHTLYISARDRGDPPRTSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRY 373

Query: 475 TASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           T S+ ED P    +LV+ A D+D +G N ++ YSLS         +   +F I+P++G +
Sbjct: 374 TFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSLS--------GNGVSKFAIDPESGVV 425

Query: 534 TTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588
           T    +D E       Y LTVTA D G  SLS TT   +EI  VD N N P F  Q    
Sbjct: 426 TLTDSVDYENTPNNHVYDLTVTATDQGPGSLSATTQLLIEIQDVDENKNSPRFDPQQAIL 485

Query: 589 NIMEDALVGTSVSQVGATDAD-VG----LNGRIHYELDPKDREEGSFVIDPASGVIRTN- 642
            I E+    + V+ V ATD+D VG     +G++ Y +       G F +D  +G ++   
Sbjct: 486 EISENLKQNSLVTTVSATDSDSVGNPSSPDGKVVYSI-VGGTGLGVFRVDSNTGEVKVAV 544

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            +LDRE  + + L   A D  T P+SS + + I + D +D+ P F        + EN P 
Sbjct: 545 PSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPS 604

Query: 703 GTTIGEIRAHDPDEGPN---AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
           GT +  +   D DEG N    V+   +    + ++  + T +  D++EL T         
Sbjct: 605 GTFVTVVVGRDADEGFNPSYTVITPGVPYKIEPSTGVIRTSKSLDQSELST--------- 655

Query: 760 RKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
            ++ ++++R ++      D +V I V    +  PV K+        ++  P+     + A
Sbjct: 656 -RELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAA 714

Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK 877
            D+ ++  +QY +  G +  L  +++ +G +      N  NV +      + T  V E+ 
Sbjct: 715 VDS-LSRPVQYTLAPGAD-GLFEVDKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEV- 771

Query: 878 AMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911
           A   L+V  +TEE  L   +     +T ++  +P
Sbjct: 772 ASASLTVE-VTEEKDLPKFSSDSYQLTVDESAAP 804



 Score =  169 bits (410), Expect = 4e-41
 Identities = 145/509 (28%), Positives = 236/509 (46%), Gaps = 45/509 (8%)

Query: 97   GALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
            G +L  + LD E+   +Y + VKAT+Q   + D L ST  + +++I+ ND++P F ++ Y
Sbjct: 1918 GRILLNSLLDFERDQTQYNLKVKATEQ---IPDGLDSTVDVKIDVINANDHFPYFDQQLY 1974

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSA-----IRYAIIGGNTQM-QFSIDSLSGDV 209
            +V + E  +V    ++ ++ A D D  ++       + Y+I     Q  +F ID  +G +
Sbjct: 1975 SVQIPESTAV--GVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQGGKFYIDPATGKI 2032

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            S+   LDYE  R + L + A D G  S      + + + +VNDN P F  S ++  V+E 
Sbjct: 2033 SVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAYEFRVAEG 2092

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
               G S+  V A DAD      +TY+       G   L  ++D  +G +  +  LD   +
Sbjct: 2093 AATGESLAIVVAVDAD---GDAVTYSK-----AGGA-LQFSVDQSTGVITLNSALD-PNK 2142

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
             +Y L V A D G    + + T                     V + E++P  T +  LT
Sbjct: 2143 NQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQ---FTNCGTVSIRENDPRDTKITQLT 2199

Query: 390  ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            ATDAD  ++ ++ Y I   +++  FSI  +   G++     LD + +  Y   + A D  
Sbjct: 2200 ATDADRGQNGQITYSIEDASSQTLFSIEPRT--GVVRSLTSLDRENKDSYNAIIKAEDGS 2257

Query: 448  GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
             + D +        + IN+ D N+  P F  A Y  SVF  AP G+ +L V ATD+D G 
Sbjct: 2258 SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAPNGSNILTVQATDADSGS 2317

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVI----NPQTGAITTNKLLDRETMSGYLLTVTARDG 556
            NA+I Y+L    S   +   D   ++    NP    + T K L  E  +  + ++     
Sbjct: 2318 NAKIKYALLD--SAGGLFRLDSSGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQP 2375

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            G P+   TT +EI V   N+  P F QQ+
Sbjct: 2376 GKPT-KYTTQIEILV--SNEEPPKFSQQV 2401



 Score =  122 bits (293), Expect = 5e-27
 Identities = 141/585 (24%), Positives = 242/585 (41%), Gaps = 64/585 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN+LD +D+ P F    Y A V E   SGT V  +   D D G N    YT+  +T    
Sbjct: 577  INLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPS--YTV--ITPGV- 631

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSD 128
                               ++I+  +G + T  SLD+ +++     V+V+ +   S  +D
Sbjct: 632  ------------------PYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTAD 673

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
                   +++ +I   +  P F    Y+V V E++    N  +  I A D+    +  ++
Sbjct: 674  -----GQVNITVISKVNRPPVFKNTPYSVKVPEEMGPLPN--LFCIAAVDS---LSRPVQ 723

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y +  G   + F +D  SG +    + +YE V  Y L I A+   S     +  L + + 
Sbjct: 724  YTLAPGADGL-FEVDKDSGRLHTKNSFNYENVDRYNLRIEARTS-SVQEVASASLTVEVT 781

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            +  D  P+F +  +Q +V E+   G ++        D   +++      +   + +    
Sbjct: 782  EEKD-LPKFSSDSYQLTVDESAAPGTTLAPGLLI-IDSDTSSDQFDCSMEAITSLHTLYN 839

Query: 309  ITIDPRSGW----VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
              +  +SG     V   G+LD    +KY   V ATD       ATA              
Sbjct: 840  FEVTQQSGRCFLRVQAGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKP 899

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422
             F+   Y + +    P G+ +VT+ A D D   + ++ YE+       RF +   N    
Sbjct: 900  EFLQESYWLSVPSSTPAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFILNDNNQLST 959

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVF 479
             +   P       RY L + A+DS  R+ ++    V +++   +    VF+ + Y  ++ 
Sbjct: 960  ASTLTP-----NVRYQLLIRASDSATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLP 1014

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            ED+   T V    AT S     ++     +S +  EA+      F I P TG +   K L
Sbjct: 1015 EDSSANTLVFTAKATRSGSSRGSRT----NSSVIGEAM------FSIKPDTGQVYLIKKL 1064

Query: 540  DRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
            D ET S + + V A+  GG   L+     ++++VDVNDN P + Q
Sbjct: 1065 DFETKSYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRYTQ 1109


>SB_56770| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 1136

 Score =  216 bits (528), Expect = 2e-55
 Identities = 187/717 (26%), Positives = 324/717 (45%), Gaps = 42/717 (5%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            +F ID  S  +   A+LD EK      L V ATDQ SP     S+   +++  +D+N N 
Sbjct: 396  LFAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSA-SAPLIVYIKDVDENQNL 454

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P F  K   +SV ED ++  +  I   KATD D G +  + Y+++ G       ++  +G
Sbjct: 455  PVFDPKAQAISVKEDTALGTS--IFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTG 512

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             V+     D +      +VI A D G+  R++   LLI +  V+D  P F    +  +V 
Sbjct: 513  VVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFTQPAYSATVL 572

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            +  P    +V + A D +   N ++ Y + +    G  DL   ++  +G + T+ +   +
Sbjct: 573  DGSPENTFVVALHATDYE---NTQIEYRLVN---VGVNDL-FQVERSTGVIRTARE-PAK 624

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
            T+   +      +  D  R A                 F    +E+++ E+  P   +V 
Sbjct: 625  TRGDQEFNQLIIEASDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDSLVC 684

Query: 388  LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            L ATD D  + + Y ITGG   G+F++   +G+   +V +  D++ E  Y++ V A    
Sbjct: 685  LAATDGDLGS-ITYSITGGGN-GKFAVDQHSGK--FSVLRSFDYELENGYIVQVQAETPN 740

Query: 448  GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA----TDSDVGINAQ 503
             ++ +A V++ I++ ++  P F    YT +V E    GTT+L  S+     D D     Q
Sbjct: 741  AKTSSANVKLIISNIDDL-PSFAKPEYTLTVPEGTTPGTTILDGSSGFQFVDDDTNPE-Q 798

Query: 504  ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
               SL  E+++  V  H +    + +        L +  +++ +   V   +   P++  
Sbjct: 799  FECSLM-EVTSMFVLEHFRVERSDSECRLTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQA 857

Query: 564  TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYEL-- 620
            T  V++S+ DVN++ P   Q  Y A +  D    T +  V A+D D    N ++ ++   
Sbjct: 858  TAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVS 917

Query: 621  DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
            D     +  F ID ++G I +   L   +   + L   A D G+PP  S V V + +   
Sbjct: 918  DADSSGQNRFQIDSSTGTITSTNLLAANN--EYKLTVKATDTGSPPMESQVSVTVSVITP 975

Query: 681  NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
              +P  F        I E+  IG ++ ++ A  P     A + YSI GG+ +++F ++  
Sbjct: 976  ITTPVKFAEANYAKTIQESLVIGNSVLQVTATGP-----AAITYSIVGGNKNDAFRIDRT 1030

Query: 741  QGSDKAELVTMVDLDYESPRKKYELVIRAA----SPPLWNDVRVEILVTDVNDNAPV 793
             G    ++     LDYE   + Y L +RA     +P +  +V V I +TDVNDN+PV
Sbjct: 1031 TG----QIAVNKPLDYEV-LQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPV 1082



 Score =  207 bits (506), Expect = 9e-53
 Identities = 186/688 (27%), Positives = 316/688 (45%), Gaps = 63/688 (9%)

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSAIRY 189
           +  T+ V I D N+  P F    Y  +V E  S  D  V  +    A D D G  S+  Y
Sbjct: 103 TATTLLVTIKDSNNFLPTFGSSVYNGTVMEG-SKEDTVVKGLENCHAEDRDTGGISS--Y 159

Query: 190 AIIGGNTQMQFSIDSLS-GDVSLVKTLDYE------QVRSYRLVIRAQDGGSPSRSNTTQ 242
            II GN +  F   +++ G+   ++ L  +         + +LV+ A+D GSP+R+ TTQ
Sbjct: 160 TIISGNEKGYFKTSTINVGEERFLQILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQ 219

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           + I++ + N+N P+F    +   V E   +   + RV A D D+G++  + Y      Y 
Sbjct: 220 IHISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYY------YL 273

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT------------A 350
             +    T++P +G V   G LD + Q+ YQL V ATD G P R A             +
Sbjct: 274 SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTIKDSQFS 333

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407
                          F        + ED P    V   TATD D    + RL Y ++G  
Sbjct: 334 PPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLYSLSGPE 393

Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSGGRSDTA----MVQINITDA 462
             G F+I   +   ++T+A  LD+++    + LTV+ATD G  + +A    +V I   D 
Sbjct: 394 A-GLFAIDPDS--AVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDE 450

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
           N   PVF+      SV ED  +GT++    ATD D G + ++ YS+   ++ E V +   
Sbjct: 451 NQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSM---VAGEGVGY--- 504

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             ++N  TG +TT  + DR+T     + + A D G    +    + I V  V+D  P F 
Sbjct: 505 -VILNETTGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFT 563

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
           Q  Y+A +++ +   T V  + ATD +   N +I Y L      +  F ++ ++GVIRT 
Sbjct: 564 QPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVND-LFQVERSTGVIRTA 619

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
           +    ++    +   + I+     + +  +V+I I+   +  P F +      + ENS  
Sbjct: 620 RE-PAKTRGDQEFNQLIIEASDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGP 678

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
             ++  + A D D G    + YSI GG  +  F+++  Q S K  ++   D + E+    
Sbjct: 679 FDSLVCLAATDGDLGS---ITYSITGG-GNGKFAVD--QHSGKFSVLRSFDYELEN---G 729

Query: 763 YELVIRAASP-PLWNDVRVEILVTDVND 789
           Y + ++A +P    +   V++++++++D
Sbjct: 730 YIVQVQAETPNAKTSSANVKLIISNIDD 757



 Score =  183 bits (446), Expect = 2e-45
 Identities = 228/937 (24%), Positives = 390/937 (41%), Gaps = 97/937 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V + N+++P FE ++Y A V E     + V  + A D D G +  V Y         L
Sbjct: 222  ISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYYY--------L 273

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P             +   F ++  +G ++   +LD +K + Y + V ATD+ SP  +  
Sbjct: 274  SP-------------LSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAA 320

Query: 131  SSTA-TIH-------VNIIDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
            +    TI         +  D   N  P F+ K    +V ED+    N  +    ATD D 
Sbjct: 321  TKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVREDLP--KNGFVFLATATDNDP 378

Query: 182  -GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY-RLVIRAQDGGSPSRSN 239
             G N  + Y++ G    + F+ID  S  V+L   LDYE+  +   L + A D GSP+ S 
Sbjct: 379  PGPNQRLLYSLSGPEAGL-FAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSA 437

Query: 240  TTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            +  L++ I+DV  N N P F       SV E+  +G SI   +A D D G + EL Y+M 
Sbjct: 438  SAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMV 497

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
              +  G V L  T    +G V T+   DR+T    ++++ A D G  PR++         
Sbjct: 498  AGEGVGYVILNET----TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVE 553

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417
                    F    Y   + +  P  T VV L ATD  E+ ++ Y +        F +   
Sbjct: 554  KVDDMYPEFTQPAYSATVLDGSPENTFVVALHATDY-ENTQIEYRLVNVGVNDLFQVERS 612

Query: 418  NGRGLITVAQPLDFKQERRY-VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
             G  + T  +P   + ++ +  L + A+D   ++ T +V I I       P F  + +  
Sbjct: 613  TGV-IRTAREPAKTRGDQEFNQLIIEASDKTRQAIT-LVNILIKSTKEVVPRFTTSAFEI 670

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
             V E++    +++ ++ATD D+G    ITYS++   + +        F ++  +G  +  
Sbjct: 671  KVPENSGPFDSLVCLAATDGDLG---SITYSITGGGNGK--------FAVDQHSGKFSVL 719

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            +  D E  +GY++ V A      + S    + IS +D   + P F +  YT  + E    
Sbjct: 720  RSFDYELENGYIVQVQAETPNAKTSSANVKLIISNID---DLPSFAKPEYTLTVPEGTTP 776

Query: 597  GTSV--SQVGATDADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTN--KAL-DR 647
            GT++     G    D   N    +E    +         F ++ +    R    K+L + 
Sbjct: 777  GTTILDGSSGFQFVDDDTNPE-QFECSLMEVTSMFVLEHFRVERSDSECRLTVIKSLFEH 835

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
             SV          +   P   +T  V + I+D+N+  P          +S ++P  T I 
Sbjct: 836  HSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIV 895

Query: 708  EIRAHDPD--EGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             + A D D  EG   V+   +   D S  N F +++  G       T+   +  +   +Y
Sbjct: 896  TVTASDLDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTG-------TITSTNLLAANNEY 948

Query: 764  ELVIRAA---SPPLWNDVRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
            +L ++A    SPP+ + V V + ++T +    PV           ++   +G    V   
Sbjct: 949  KLTVKATDTGSPPMESQVSVTVSVITPIT--TPVKFAEANYAKTIQESLVIG--NSVLQV 1004

Query: 820  DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879
             A     + Y I+ GN  +   ++ TTG + ++  L+  V +   + V  T      K  
Sbjct: 1005 TATGPAAITYSIVGGNKNDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIA 1064

Query: 880  MQLSVRLITEEM-------LL--NSITVRLNDMTAEQ 907
             +++V +   ++       LL  N  TV +N  T EQ
Sbjct: 1065 AEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQ 1101



 Score =  176 bits (428), Expect = 2e-43
 Identities = 225/918 (24%), Positives = 383/918 (41%), Gaps = 92/918 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIELVTA 67
           + + D N+  P F    Y  +V EG+   T V  L+   A D+D G  +   YTI  ++ 
Sbjct: 109 VTIKDSNNFLPTFGSSVYNGTVMEGSKEDTVVKGLENCHAEDRDTGGISS--YTI--ISG 164

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
           +    E             +   +I      L T   + R+      ++V+A D  SP  
Sbjct: 165 N----EKGYFKTSTINVGEERFLQI------LTTDLPITRDTTNTIKLVVEARDSGSPAR 214

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              + T  IH+++ + N+N P+F ++ YT  V E+  +  N  +A++ A D D G + ++
Sbjct: 215 ---TVTTQIHISVENRNENTPKFEKEEYTAMVMEETQL--NSPVARVHAKDTDQGMSGSV 269

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            Y +        F+++ ++G V LV TLDY++  SY+L + A D GSP R   T++++ I
Sbjct: 270 YYYL--SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTI 327

Query: 248 RDVN------------DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTY 294
           +D              + AP F       +V E++P    +    A D D  G N  L Y
Sbjct: 328 KDSQFSPPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLY 387

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXX 353
           +++  +  G       IDP S  V  +  LD E       L VTATD G P  SA+A   
Sbjct: 388 SLSGPE-AG----LFAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLI 442

Query: 354 XXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409
                         F P    + + ED   GT + T  ATD D   D  L Y +  G   
Sbjct: 443 VYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMVAGEGV 502

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467
           G + I ++   G++T A   D K      + ++A D G   R+    + I +   ++  P
Sbjct: 503 G-YVILNET-TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYP 560

Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            F    Y+A+V + +P  T V+ + ATD +   N QI Y L +   N+        F + 
Sbjct: 561 EFTQPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVNDL-------FQVE 610

Query: 528 PQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
             TG I T +     R       L + A D    +    T V I +    +  P F    
Sbjct: 611 RSTGVIRTAREPAKTRGDQEFNQLIIEASD---KTRQAITLVNILIKSTKEVVPRFTTSA 667

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
           +   + E++    S+  + ATD D+   G I Y +       G F +D  SG     ++ 
Sbjct: 668 FEIKVPENSGPFDSLVCLAATDGDL---GSITYSI--TGGGNGKFAVDQHSGKFSVLRSF 722

Query: 646 DRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           D E     +   V +   TP  ++S+  V + I +I+D P  F     T  + E +  GT
Sbjct: 723 DYE---LENGYIVQVQAETPNAKTSSANVKLIISNIDDLPS-FAKPEYTLTVPEGTTPGT 778

Query: 705 TI--GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE---TRQGSDKAELVTMVDLDYESP 759
           TI  G       D+  N    +     + ++ F LE     +   +  L  +  L     
Sbjct: 779 TILDGSSGFQFVDDDTNP-EQFECSLMEVTSMFVLEHFRVERSDSECRLTVIKSLFEHHS 837

Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816
             ++  +++    A P +    +V++ + DVN++AP +           D     P   V
Sbjct: 838 VTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNHAPEITQASYWATVSSDTPTRTPIVTV 897

Query: 817 PAYDADVTD---KLQYRILS---GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
            A D D  +   ++ ++ +S    +  N   ++ +TG++T +  L  N     T++ + T
Sbjct: 898 TASDLDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTGTITSTNLLAANNEYKLTVKATDT 957

Query: 871 DGVNEIKAMMQLSVRLIT 888
            G   +++ + ++V +IT
Sbjct: 958 -GSPPMESQVSVTVSVIT 974



 Score =  172 bits (419), Expect = 3e-42
 Identities = 187/729 (25%), Positives = 315/729 (43%), Gaps = 78/729 (10%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S P  ++  I  +D N + PVF+ +    SV+E  + GT++ T KATD+D G + E+EY+
Sbjct: 438  SAPLIVY--IKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYS 495

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
              +V  + +                     ++  +G + T A  DR+      V++ A D
Sbjct: 496  --MVAGEGVG-----------------YVILNETTGVVTTAAMFDRKTNPVVEVVIAAHD 536

Query: 122  QAS-PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
            + + P + +      I V  +DD   YP+F++  Y+ +V +     +N  +  + ATD +
Sbjct: 537  KGTFPRTSKFY--LLIQVEKVDDM--YPEFTQPAYSATVLD--GSPENTFVVALHATDYE 590

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV----KTLDYEQVRSYRLVIRAQDGGSPS 236
               N+ I Y ++       F ++  +G +       KT   ++    +L+I A D    +
Sbjct: 591  ---NTQIEYRLVNVGVNDLFQVERSTGVIRTAREPAKTRGDQEFN--QLIIEASD---KT 642

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            R   T + I I+   +  PRF TS F+  V EN     S+V + A D D G    +TY++
Sbjct: 643  RQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDSLVCLAATDGDLG---SITYSI 699

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
            T     G  +    +D  SG        D E +  Y + V A     P    ++      
Sbjct: 700  T-----GGGNGKFAVDQHSGKFSVLRSFDYELENGYIVQVQAET---PNAKTSSANVKLI 751

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA--------TDADEDNRLHYEITGGNT 408
                     F   +Y + + E   PGT ++  ++        T+ ++      E+T    
Sbjct: 752  ISNIDDLPSFAKPEYTLTVPEGTTPGTTILDGSSGFQFVDDDTNPEQFECSLMEVTSMFV 811

Query: 409  RGRFSITSQNGRGLITVAQPL-DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465
               F +   +    +TV + L +     ++   V  T+        TA V ++I D NN+
Sbjct: 812  LEHFRVERSDSECRLTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQATAKVDLSIKDVNNH 871

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQF 524
            AP    A Y A+V  D P  T ++ V+A+D D    N Q+ +   S+  +        +F
Sbjct: 872  APEITQASYWATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSDADSSG----QNRF 927

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
             I+  TG IT+  LL     + Y LTV A D G P +     V +SV+        F + 
Sbjct: 928  QIDSSTGTITSTNLLAAN--NEYKLTVKATDTGSPPMESQVSVTVSVITPITTPVKFAEA 985

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
             Y   I E  ++G SV QV AT         I Y +   ++ + +F ID  +G I  NK 
Sbjct: 986  NYAKTIQESLVIGNSVLQVTATGP-----AAITYSIVGGNKND-AFRIDRTTGQIAVNKP 1039

Query: 645  LDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTFYISENSP 701
            LD E + ++ L   A  +  TP  ++ V V I + D+ND+ PVF   S+  T  ++  +P
Sbjct: 1040 LDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTP 1099

Query: 702  IGTTIGEIR 710
              T + + R
Sbjct: 1100 EQTVVFKAR 1108



 Score =  147 bits (357), Expect = 1e-34
 Identities = 128/481 (26%), Positives = 220/481 (45%), Gaps = 43/481 (8%)

Query: 421 GLITVAQPLDFK--QERRYVLT-VSATDSGGRSDTAM-VQINITDANNYAPVFENAPYTA 476
           G++T A+P +++  +   + LT V    S G   TA  + + I D+NN+ P F ++ Y  
Sbjct: 69  GVVTSAKPFEYRIGESNTFTLTIVKRQRSQGFGGTATTLLVTIKDSNNFLPTFGSSVYNG 128

Query: 477 SVFEDAPIGTTVLVVS---ATDSDVGINAQITYSLSSE---ISNEAVAHHDQQFVINPQT 530
           +V E +   T V  +    A D D G  +  T    +E        +   +++F+     
Sbjct: 129 TVMEGSKEDTVVKGLENCHAEDRDTGGISSYTIISGNEKGYFKTSTINVGEERFL----- 183

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
             +TT+  + R+T +   L V ARD G P+ + TT + ISV + N+N P F+++ YTA +
Sbjct: 184 QILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTAMV 243

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
           ME+  + + V++V A D D G++G ++Y L P       F ++P +GV+     LD +  
Sbjct: 244 MEETQLNSPVARVHAKDTDQGMSGSVYYYLSPL---SSYFTVNPITGVVILVGTLDYQKQ 300

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP------------PVFESDCLTFYISE 698
           +++ L  +A D G+P + +   V + I+D   SP            PVF    L   + E
Sbjct: 301 SSYQLTVMATDRGSPRREAATKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVRE 360

Query: 699 NSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
           + P    +    A D D  GPN  + YS+  G ++  F+++     D A +     LDYE
Sbjct: 361 DLPKNGFVFLATATDNDPPGPNQRLLYSL-SGPEAGLFAID----PDSAVVTLAAALDYE 415

Query: 758 SPRKKYELVIRA---ASPPLWNDVRVEILVTDV--NDNAPVM-KDFQIIFNNYKDCFPVG 811
                  L + A    SP L     + + + DV  N N PV     Q I           
Sbjct: 416 KGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTS 475

Query: 812 PF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
            F  +    D+    +L+Y +++G     ++LNETTG +T +   +     +  + ++  
Sbjct: 476 IFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTGVVTTAAMFDRKTNPVVEVVIAAH 535

Query: 871 D 871
           D
Sbjct: 536 D 536


>SB_35949| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 521

 Score =  214 bits (522), Expect = 1e-54
 Identities = 166/525 (31%), Positives = 245/525 (46%), Gaps = 28/525 (5%)

Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
           + ++ ATDAD G N+ I Y IIGGN    FSIDS +G +S + +LD+E    + L+I A+
Sbjct: 9   LLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAK 68

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           DGG+   + T  + + + +  DN P F   ++  +V ENVP G  + RV A   D+  N 
Sbjct: 69  DGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDK--NG 126

Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
            ++Y +   D T N+ L   +D   G +  +G +DRE +A+Y L V A  G   P SA A
Sbjct: 127 SISYAIVSGDPT-NLFL---VDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQA 182

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNT 408
           T              F      V++      G  V    A D D  ++  + Y++T  N 
Sbjct: 183 TVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLT-SNA 241

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
            G   I S +  G+I +A+ L    E +Y + V A+DSG     + + I+IT + N+ P 
Sbjct: 242 EGLLWINSTS--GVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLSINHPPK 299

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           F  + Y   V    P+      V A D D G N Q+ YS+     NE     +  F I P
Sbjct: 300 FTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ--GNE-----EGLFGIFP 352

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
             G +   K L +     Y L V A DGGVPS S +  V I + D ND+  +F    +  
Sbjct: 353 -GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRF 411

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            + E++  GT V  + A   D      I Y L      E  F +D  SG I T   LDRE
Sbjct: 412 AVAENSSPGTLVGTLVAHALDHSRTKDIVYSL---ISSESHFAVDVRSGQITTRVRLDRE 468

Query: 649 SVA------THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
            +        + ++A A+   T  +    IV + + D+ND+ PVF
Sbjct: 469 ELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVF 513



 Score =  196 bits (477), Expect = 3e-49
 Identities = 155/536 (28%), Positives = 246/536 (45%), Gaps = 35/536 (6%)

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN P G  +++V A DADEG NA ++Y +   +  GN     +ID  +G + T   LD E
Sbjct: 2   ENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGN----FSIDSSTGVISTLASLDHE 56

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
            +  + L+++A DGG+   + TA               F+   Y   + E+ P GT V  
Sbjct: 57  VEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGR 116

Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
           + AT  D++  + Y I  G+    F + S  G  +I +   +D +++ +Y+L V A    
Sbjct: 117 VYATTKDKNGSISYAIVSGDPTNLFLVDSTGG--IIKINGDMDREEKAQYLLAVIARVGT 174

Query: 448 GR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
            +  S  A V I + D N+ AP F  +     +     +G  V   +A D D G N  + 
Sbjct: 175 VKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVR 234

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
           Y L+S               IN  +G I   + L     + Y + V A D G P    T 
Sbjct: 235 YQLTSNAEG--------LLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTM 286

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
            + I++  +N + P F    Y  +++    +      V A D D G NG++ Y + P+  
Sbjct: 287 TIHITL-SIN-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSI-PQGN 343

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
           EEG F I P  G +   K+L +    ++DL   A DGG P  S++V V I I+D ND   
Sbjct: 344 EEGLFGIFPG-GKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRS 402

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
           +F ++   F ++ENS  GT +G + AH  D      + YS+   +  + F+++ R G   
Sbjct: 403 LFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSE--SHFAVDVRSG--- 457

Query: 746 AELVTMVDLDYESPRKKY-ELVIRAASPPLWNDVRVE-------ILVTDVNDNAPV 793
            ++ T V LD E   K     V    +  ++ND  ++       + VTD+NDNAPV
Sbjct: 458 -QITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPV 512



 Score =  171 bits (416), Expect = 7e-42
 Identities = 142/507 (28%), Positives = 230/507 (45%), Gaps = 36/507 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ID  +G + T ASLD E    +++++ A D  +  +   + TA ++V +++  DN P 
Sbjct: 38  FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYA---AKTAVVNVTVLNKADNLPV 94

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F  + Y  +V E+  V    ++ ++ AT  D   N +I YAI+ G+    F +DS  G +
Sbjct: 95  FLYEMYNFTVYEN--VPKGTLVGRVYATTKD--KNGSISYAIVSGDPTNLFLVDSTGGII 150

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            +   +D E+   Y L + A+ G     S    + I + D NDNAP+F TS     +   
Sbjct: 151 KINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGT 210

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
             +G  +    A D D G N  + Y +T      N +  + I+  SG +  + +L    +
Sbjct: 211 WLVGQVVYNAAAVDLDAGKNGLVRYQLTS-----NAEGLLWINSTSGVIKLARKLTDGDE 265

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
            +Y + V A+D G PP+ +T T              F    Y   +   +P       + 
Sbjct: 266 TQYTVQVLASDSGSPPQHSTMTIHITLSINHPPK--FTLSSYVTHVLASQPLSYQFFYVV 323

Query: 390 ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
           A D D  ++ +L Y I  GN  G F I      G + + + L    +  Y L V ATD G
Sbjct: 324 AVDQDSGKNGQLFYSIPQGNEEGLFGIFPG---GKLYIRKSLLQALKGSYDLIVRATDGG 380

Query: 448 GRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
             S +A V + I   D+N++  +F N  +  +V E++  GT V  + A   D      I 
Sbjct: 381 VPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIV 440

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM------SGYLLTVTARDGGVP 559
           YSL   IS+E+       F ++ ++G ITT   LDRE +      + Y++   A      
Sbjct: 441 YSL---ISSES------HFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTT 491

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLY 586
              D   V ++V D+NDN PVF + +Y
Sbjct: 492 IKRDKAIVIVTVTDLNDNAPVFSRAVY 518



 Score =  161 bits (391), Expect = 7e-39
 Identities = 138/472 (29%), Positives = 213/472 (45%), Gaps = 44/472 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VL+  D+ PVF  + Y  +V E    GT V  + AT +D  KN  + Y I  V+ D  
Sbjct: 83  VTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKD--KNGSISYAI--VSGDPT 138

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N                 +F +D   G +     +DRE+ A+Y + V A  +   V   L
Sbjct: 139 N-----------------LFLVDSTGGIIKINGDMDREEKAQYLLAVIA--RVGTVKP-L 178

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+ AT+++ ++D NDN PQFS  T +V VD D +     V+    A D D G N  +RY 
Sbjct: 179 SAQATVNIEVLDRNDNAPQFS--TSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQ 236

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           +   N +    I+S SG + L + L       Y + + A D GSP + +T  + I +  +
Sbjct: 237 LT-SNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL-SI 294

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           N + P+F  S +   V  + P+ Y    V A D D G N +L Y++      GN +    
Sbjct: 295 N-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ----GNEEGLFG 349

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           I P  G +Y    L +  +  Y L+V ATDGG P  SA+                F+   
Sbjct: 350 IFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNT 408

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           +   +AE+  PGT V TL A   D         +  ++   F++  ++G+  IT    LD
Sbjct: 409 FRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQ--ITTRVRLD 466

Query: 431 FKQ------ERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPY 474
            ++         Y++   A   D+  + D A+V + +TD N+ APVF  A Y
Sbjct: 467 REELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVY 518



 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 50/163 (30%), Positives = 82/163 (50%), Gaps = 11/163 (6%)

Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
           EN P G  + ++ A D DEG NAV+ Y I GG+++ +FS+++  G     + T+  LD+E
Sbjct: 2   ENEPPGKLL-QVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGV----ISTLASLDHE 56

Query: 758 SPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF- 813
              + + L+I A    +        V + V +  DN PV       F  Y++  P G   
Sbjct: 57  V-EEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENV-PKGTLV 114

Query: 814 GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
           GRV A   D    + Y I+SG+  NL L++ T G + ++  ++
Sbjct: 115 GRVYATTKDKNGSISYAIVSGDPTNLFLVDSTGGIIKINGDMD 157



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 45/160 (28%), Positives = 71/160 (44%), Gaps = 28/160 (17%)

Query: 2   SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
           SVP  I+ Q    D NDH  +F    +  +V E +S GT V TL A   D  +  ++ Y+
Sbjct: 387 SVPVTIYIQ----DSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYS 442

Query: 62  IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVK 118
             L+++++                    F +D RSG + TR  LDRE++ + T   V + 
Sbjct: 443 --LISSESH-------------------FAVDVRSGQITTRVRLDREELIKNTGSNVYIM 481

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
             +     +      A + V + D NDN P FS   Y ++
Sbjct: 482 QAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAIT 521



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 809 PVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866
           P G   +V A DAD      + Y I+ GNN     ++ +TG ++    L+  V +  ++ 
Sbjct: 5   PPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLI 64

Query: 867 VSVTDGVNEIKA 878
           +S  DG N+  A
Sbjct: 65  ISAKDGGNKYAA 76


>SB_50345| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 1021

 Score =  202 bits (492), Expect = 4e-51
 Identities = 195/731 (26%), Positives = 331/731 (45%), Gaps = 69/731 (9%)

Query: 89  VFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSDRLSSTATIHVNIID 142
           +F I+  +G L T+  L+REK+        + + +K T     VS    +T    V ++D
Sbjct: 64  IFEINAATGVLRTKILLNREKLPPSAQGDIFQIQIKVTTDTGGVS----ATIPTEVRVLD 119

Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202
            ND+ P+F +    + + E  S  +       +A DAD+G NS   Y I+ GN    FS+
Sbjct: 120 INDHSPKFPQDFEELQISE--SAPERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSL 177

Query: 203 D--SLSGDVSLV-----KTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNA 254
                S D+  V     K LD E    Y+LVI A DGG P  RS   ++ I I D ND++
Sbjct: 178 SLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHS 237

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P F    +  SV EN P G  ++RV A D D G N E+ + + +    G       +D  
Sbjct: 238 PEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDESPERG----LFRMDEY 293

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
           +G ++T+  LD E +++Y+L V A D G       A                     +V 
Sbjct: 294 TGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKVEDKNDNAPTIQVKLLQVP 353

Query: 375 LA-------EDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS-QNGRGLIT 424
            A       ED   G+ V  +   D D    ++   ++T  + +  F++    N    + 
Sbjct: 354 NAARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLLHHKHDFALRRIFNTFYNLE 413

Query: 425 VAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
           V +PL+  ++  Y +   A D G     ++ +++ ++I D N + P +       ++ ++
Sbjct: 414 VQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLI-LHIEDKNRHTPTYPIPSRDITIIDN 472

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEI---SNEAVAHHDQQFVINPQTGAITTNKL 538
               T V V  A D D      + Y+++S +    N  V    + F+   ++G +     
Sbjct: 473 TQPATIVSVFKAEDPDTDREGDLDYTITSLVMGEKNVTVDDPGRYFMYGQKSGELVVIPK 532

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           L       + LT+ A+D G         + ++V          K Q Y  +I+E++ +GT
Sbjct: 533 LWCAFTPSFRLTLQAKDNGRERKHGEMTLHVTV-------KCAKYQ-YNFSIVENSPLGT 584

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            V ++       G    + + +    R++  F+I+ A+GVIRT + LDRE+VA +DL  +
Sbjct: 585 IVGRIVVNTRAPG--KVVSFSVITTGRQD--FMINNATGVIRTTRRLDREAVAAYDLVVL 640

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             DG    + +++   + + D+ND+ PVF   +D     +  N+  G  +  IRA DPD 
Sbjct: 641 VTDGDVEMRLASI---VNVVDVNDNAPVFIGLNDNDVMEVPSNAKRGDEVVTIRATDPDS 697

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773
           G N  + YS+  G+D  +F L+     D+ ELV + +  ++S    Y L I+A+   +PP
Sbjct: 698 GLNGKIQYSLIAGNDDKTFILD----KDRGELV-VFNYMFQS---SYVLTIKASDSGNPP 749

Query: 774 LWNDVRVEILV 784
             + VR+ I V
Sbjct: 750 SESLVRIRIRV 760



 Score =  187 bits (456), Expect = 1e-46
 Identities = 185/692 (26%), Positives = 286/692 (41%), Gaps = 63/692 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  ++ VLD NDHSP F     E  + E A   +     +A D DIG N+  EY I    
Sbjct: 111 IPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRGN 170

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            D L                 D+  +      L+    LDRE    Y +++ A D   P+
Sbjct: 171 EDGL-------FSLSLKRFSPDMIYV-----YLVNTKRLDRETRDFYQLVIVAVDGGFPL 218

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               S    +++ I+D ND+ P+FS+  YT SV E+    +   + ++ A D D+G N  
Sbjct: 219 PR--SGRKEVNITILDSNDHSPEFSKDFYTASVPEN--APNGTYLLRVTAIDQDIGKNGE 274

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           I + +     +  F +D  +G++     LDYE    YRL + AQD G  S     Q+ I 
Sbjct: 275 IMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIK 334

Query: 247 IRDVNDNAPRFYTSLFQES-------VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           + D NDNAP     L Q         V E++  G ++  V+  D D  +       +T  
Sbjct: 335 VEDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLL 394

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
            +  +  L    +     +     L+   Q+ Y++   A D G P      +        
Sbjct: 395 HHKHDFALRRIFNTFYN-LEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLILHIEDK 453

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITG---GNTR----- 409
                 +     ++ + ++  P T V    A D D D    L Y IT    G        
Sbjct: 454 NRHTPTYPIPSRDITIIDNTQPATIVSVFKAEDPDTDREGDLDYTITSLVMGEKNVTVDD 513

Query: 410 -GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
            GR+ +  Q   G + V   L       + LT+ A D+G       + +++T        
Sbjct: 514 PGRYFMYGQKS-GELVVIPKLWCAFTPSFRLTLQAKDNGRERKHGEMTLHVT------VK 566

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
                Y  S+ E++P+GT V         + +N   T +    +S   +    Q F+IN 
Sbjct: 567 CAKYQYNFSIVENSPLGTIV-------GRIVVN---TRAPGKVVSFSVITTGRQDFMINN 616

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            TG I T + LDRE ++ Y L V   DG V     +    ++VVDVNDN PVF   L   
Sbjct: 617 ATGVIRTTRRLDREAVAAYDLVVLVTDGDVEMRLASI---VNVVDVNDNAPVF-IGLNDN 672

Query: 589 NIME---DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
           ++ME   +A  G  V  + ATD D GLNG+I Y L     ++ +F++D   G +     +
Sbjct: 673 DVMEVPSNAKRGDEVVTIRATDPDSGLNGKIQYSL-IAGNDDKTFILDKDRGELVVFNYM 731

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            + S   + L   A D G PP  S V + I++
Sbjct: 732 FQSS---YVLTIKASDSGNPPSESLVRIRIRV 760



 Score =  155 bits (377), Expect = 4e-37
 Identities = 149/578 (25%), Positives = 239/578 (41%), Gaps = 60/578 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I +LD NDHSP F    Y ASV E A +GT +L + A DQDIGKN E+ + ++       
Sbjct: 228 ITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDE------ 281

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +PE             + +FR+D  +G + T A LD E  + Y + V A DQ     D +
Sbjct: 282 SPE-------------RGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGP---DSI 325

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVS-------VDEDISVTDNPVIAKIKATDADVGA 183
              A + + + D NDN P    K   V        V EDI+   N  I +++  D+ +  
Sbjct: 326 PVRAQVTIKVEDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTV 385

Query: 184 NSAIRYAIIGGNTQMQFS-IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
           NS +   ++          I +   ++ + + L+  +   Y++   A+D G P+      
Sbjct: 386 NSVVDVTLLHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNS 445

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK--- 299
           L+++I D N + P +       ++ +N      +   +A D D     +L YT+T     
Sbjct: 446 LILHIEDKNRHTPTYPIPSRDITIIDNTQPATIVSVFKAEDPDTDREGDLDYTITSLVMG 505

Query: 300 DYTGNVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           +    VD P        +SG +    +L       ++L + A D G   +    T     
Sbjct: 506 EKNVTVDDPGRYFMYGQKSGELVVIPKLWCAFTPSFRLTLQAKDNGRERKHGEMTLHVTV 565

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416
                        QY   + E+ P GT V  +          + + +    T GR     
Sbjct: 566 KCAKY--------QYNFSIVENSPLGTIVGRIVVNTRAPGKVVSFSVI---TTGRQDFMI 614

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE--NAPY 474
            N  G+I   + LD +    Y L V  TD       A + +N+ D N+ APVF   N   
Sbjct: 615 NNATGVIRTTRRLDREAVAAYDLVVLVTDGDVEMRLASI-VNVVDVNDNAPVFIGLNDND 673

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              V  +A  G  V+ + ATD D G+N +I YSL +        + D+ F+++   G + 
Sbjct: 674 VMEVPSNAKRGDEVVTIRATDPDSGLNGKIQYSLIA-------GNDDKTFILDKDRGELV 726

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
               + +   S Y+LT+ A D G P       + I VV
Sbjct: 727 VFNYMFQ---SSYVLTIKASDSGNPPSESLVRIRIRVV 761



 Score =  147 bits (357), Expect = 1e-34
 Identities = 168/695 (24%), Positives = 280/695 (40%), Gaps = 64/695 (9%)

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           D G  S +  T+  + + D+ND++P+F     +  +SE+ P        +A DAD G N+
Sbjct: 103 DTGGVSATIPTE--VRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNS 160

Query: 291 ELTYTMTDKDYTGNVDLPI-TIDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDP-PR 346
              Y +   +  G   L +    P   +VY   + +LDRET+  YQL++ A DGG P PR
Sbjct: 161 IQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPR 220

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404
           S                  F    Y   + E+ P GT ++ +TA D D  ++  + + + 
Sbjct: 221 SGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLD 280

Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDA 462
               RG F +    G   I     LD++ +  Y LTV A D G  S    A V I + D 
Sbjct: 281 ESPERGLFRMDEYTGE--IWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKVEDK 338

Query: 463 NNYAPVFE-------NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           N+ AP  +       NA     V ED   G+ V +V   D D  +         + + + 
Sbjct: 339 NDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTV-------NSVVDV 391

Query: 516 AVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
            + HH   F +         +   + L+    S Y +   ARD GVP+L     + + + 
Sbjct: 392 TLLHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLILHIE 451

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
           D N + P +        I+++    T VS   A D D    G + Y +      E +  +
Sbjct: 452 DKNRHTPTYPIPSRDITIIDNTQPATIVSVFKAEDPDTDREGDLDYTITSLVMGEKNVTV 511

Query: 633 D---------PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
           D           SG +     L      +  L   A D G   +   + +H+ ++     
Sbjct: 512 DDPGRYFMYGQKSGELVVIPKLWCAFTPSFRLTLQAKDNGRERKHGEMTLHVTVKCAKYQ 571

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
                     F I ENSP+GT +G I  +     P  VV +S+        F +    G 
Sbjct: 572 --------YNFSIVENSPLGTIVGRIVVN--TRAPGKVVSFSVI-TTGRQDFMINNATG- 619

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM-----KDFQ 798
               + T   LD E+    Y+LV+      +   +   + V DVNDNAPV       D  
Sbjct: 620 ---VIRTTRRLDREAV-AAYDLVVLVTDGDVEMRLASIVNVVDVNDNAPVFIGLNDNDVM 675

Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858
            + +N K    V    R    D+ +  K+QY +++GN+    +L++  G + +    N  
Sbjct: 676 EVPSNAKRGDEVVTI-RATDPDSGLNGKIQYSLIAGNDDKTFILDKDRGELVV---FNYM 731

Query: 859 VPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEML 892
                 + +  +D  N   ++++++ +R++  E+L
Sbjct: 732 FQSSYVLTIKASDSGNPPSESLVRIRIRVVPPEVL 766



 Score =  130 bits (313), Expect = 2e-29
 Identities = 100/326 (30%), Positives = 156/326 (47%), Gaps = 13/326 (3%)

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRL-----HYEITGGNTRGRFSITSQNG--RGLITVA 426
           ++ E++ PG  V  ++ TD  +  RL      Y+I G    G F I +  G  R  I + 
Sbjct: 23  QVKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGP-ADGIFEINAATGVLRTKILLN 81

Query: 427 Q---PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           +   P   + +   +     TD+GG S T   ++ + D N+++P F        + E AP
Sbjct: 82  REKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAP 141

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             +   +  A D+D+G N+   Y +     +   +   ++F  +     +   K LDRET
Sbjct: 142 ERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRET 201

Query: 544 MSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              Y L + A DGG P   S   +V I+++D ND+ P F +  YTA++ E+A  GT + +
Sbjct: 202 RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLR 261

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A D D+G NG I + LD +  E G F +D  +G I TN  LD E  + + L  VA D 
Sbjct: 262 VTAIDQDIGKNGEIMFYLD-ESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQ 320

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFE 688
           G         V IK+ED ND+ P  +
Sbjct: 321 GPDSIPVRAQVTIKVEDKNDNAPTIQ 346



 Score = 87.8 bits (208), Expect = 1e-16
 Identities = 97/332 (29%), Positives = 154/332 (46%), Gaps = 27/332 (8%)

Query: 590 IMEDALVGTSVSQVGATDADVGLN---GRIHYELD-PKDREEGSFVIDPASGVIRTNKAL 645
           + E+   G  V  V  TD    L    G+I Y++  P D   G F I+ A+GV+RT   L
Sbjct: 24  VKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGPAD---GIFEINAATGVLRTKILL 80

Query: 646 DRESV---ATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
           +RE +   A  D+  + I   T     S+T+   +++ DIND  P F  D     ISE++
Sbjct: 81  NREKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESA 140

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD---LDYE 757
           P  +     RA D D G N++  Y I  G++   FSL  ++ S     V +V+   LD E
Sbjct: 141 PERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRE 200

Query: 758 SPRKKYELVIRAASP--PLWNDVRVEILVT--DVNDNAP-VMKDFQIIFNNYKDCFPVGP 812
           + R  Y+LVI A     PL    R E+ +T  D ND++P   KDF     +  +  P G 
Sbjct: 201 T-RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTA--SVPENAPNGT 257

Query: 813 F-GRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
           +  RV A D D+    ++ + +       L  ++E TG +  +  L+  V     + V  
Sbjct: 258 YLLRVTAIDQDIGKNGEIMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVA 317

Query: 870 TD-GVNEIKAMMQLSVRLITEEMLLNSITVRL 900
            D G + I    Q+++++  +     +I V+L
Sbjct: 318 QDQGPDSIPVRAQVTIKVEDKNDNAPTIQVKL 349


>SB_56686| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 1888

 Score =  199 bits (486), Expect = 2e-50
 Identities = 164/519 (31%), Positives = 242/519 (46%), Gaps = 38/519 (7%)

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LL 244
           + YAI  GN    F +D+ +G V L+ TLDY +  SYRLVIRA DGG+          L 
Sbjct: 3   VSYAIYSGNQAGMFRVDA-NGTVYLLGTLDYARAPSYRLVIRATDGGAKEMRKHADFTLT 61

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + + D+NDNAP+F +      V E   IG  I  + A DAD   N +++Y    K  +GN
Sbjct: 62  VLVEDINDNAPKFASDKTMVDVYETSKIGQVITVITATDADASTNGQVSY----KIASGN 117

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDPPRSATATXXXXXXXXX 360
            D    +D ++G V  S  LD E          L+V ATD G P   + A+         
Sbjct: 118 DDDYFRLDSKTGHVTLSKSLDLEILHNEGWNRTLVVIATDHGTPRLHSNASFVFRLNSVN 177

Query: 361 XXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417
                +       + L+ED   G+ +  L+ATD D   D  + Y I  GN   +F +   
Sbjct: 178 EFPPVWTGNANLSLSLSEDILVGSKIGRLSATDRDYGLDGEIRYIILSGNGERKFHLDEV 237

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENA 472
              G+IT+  PLD ++   + L V A+D     S  R   A+V I + D N+  P F+  
Sbjct: 238 T--GVITIHAPLDRERTSYFRLRVQASDCSKKASSRRRVYAVVDIKVKDVNDNKPTFQRK 295

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            Y   V E A IG  ++ V A+DSD G N ++TYS+   IS   +      F I+ QTG 
Sbjct: 296 SYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSI---ISGNDLGF----FGIDSQTGT 348

Query: 533 ITTNKLLDRETMSG-----YLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLY 586
           +   K LD ET        Y+LT++A+D G P +L+ T  + I +  VN   P       
Sbjct: 349 LRVRKSLDLETQVHVYDLIYILTISAQDQGTPRALNSTAIITIEIRSVNQFTPGLPAPSD 408

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
             +  E + VG  V    ATD D G +G I + +     E  +F ID ++G I   K L+
Sbjct: 409 VIH-PESSPVGFEVVDWNATDKDFGADGIIRFAIF-HGNEGNTFDIDSSTGKITVGKKLN 466

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVI--VHIKIEDINDS 683
                 + L     D G   Q  +++  V +++ ++ND+
Sbjct: 467 FTLYPRYFLHINISDSGPTSQRRSLVTKVTVRVTNLNDN 505



 Score =  179 bits (436), Expect = 3e-44
 Identities = 151/509 (29%), Positives = 233/509 (45%), Gaps = 38/509 (7%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +FR+D  +G +    +LD  +   Y ++++ATD  +    R  +  T+ V + D NDN P
Sbjct: 15  MFRVDA-NGTVYLLGTLDYARAPSYRLVIRATDGGAKEM-RKHADFTLTVLVEDINDNAP 72

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
           +F+     V V E   +    VI  I ATDAD   N  + Y I  GN    F +DS +G 
Sbjct: 73  KFASDKTMVDVYETSKI--GQVITVITATDADASTNGQVSYKIASGNDDDYFRLDSKTGH 130

Query: 209 VSLVKTLDYEQVR----SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY-TSLFQ 263
           V+L K+LD E +     +  LV+ A D G+P   +    +  +  VN+  P +   +   
Sbjct: 131 VTLSKSLDLEILHNEGWNRTLVVIATDHGTPRLHSNASFVFRLNSVNEFPPVWTGNANLS 190

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            S+SE++ +G  I R+ A D D G++ E+ Y +     +GN +    +D  +G +     
Sbjct: 191 LSLSEDILVGSKIGRLSATDRDYGLDGEIRYII----LSGNGERKFHLDEVTGVITIHAP 246

Query: 324 LDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           LDRE  + ++L V A+D        R   A               F    Y V + E   
Sbjct: 247 LDRERTSYFRLRVQASDCSKKASSRRRVYAVVDIKVKDVNDNKPTFQRKSYYVVVLETAQ 306

Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR-- 436
            G  ++T+ A+D+DE  + R+ Y I  GN  G F I SQ   G + V + LD + +    
Sbjct: 307 IGGAIITVHASDSDEGPNGRVTYSIISGNDLGFFGIDSQT--GTLRVRKSLDLETQVHVY 364

Query: 437 ---YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
              Y+LT+SA D G     + TA++ I I   N + P    AP      E +P+G  V+ 
Sbjct: 365 DLIYILTISAQDQGTPRALNSTAIITIEIRSVNQFTPGLP-APSDVIHPESSPVGFEVVD 423

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            +ATD D G +  I +++     NE        F I+  TG IT  K L+      Y L 
Sbjct: 424 WNATDKDFGADGIIRFAIFH--GNEG-----NTFDIDSSTGKITVGKKLNFTLYPRYFLH 476

Query: 551 VTARDGGVPS--LSDTTDVEISVVDVNDN 577
           +   D G  S   S  T V + V ++NDN
Sbjct: 477 INISDSGPTSQRRSLVTKVTVRVTNLNDN 505



 Score =  178 bits (434), Expect = 5e-44
 Identities = 141/498 (28%), Positives = 229/498 (45%), Gaps = 48/498 (9%)

Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
           Y I  GN  G F +   +  G + +   LD+ +   Y L + ATD G +         +T
Sbjct: 5   YAIYSGNQAGMFRV---DANGTVYLLGTLDYARAPSYRLVIRATDGGAKEMRKHADFTLT 61

Query: 461 ----DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
               D N+ AP F +      V+E + IG  + V++ATD+D   N Q++Y ++S      
Sbjct: 62  VLVEDINDNAPKFASDKTMVDVYETSKIGQVITVITATDADASTNGQVSYKIAS------ 115

Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETM--SGY--LLTVTARDGGVPSLSDTTDVEISVV 572
             + D  F ++ +TG +T +K LD E +   G+   L V A D G P L         + 
Sbjct: 116 -GNDDDYFRLDSKTGHVTLSKSLDLEILHNEGWNRTLVVIATDHGTPRLHSNASFVFRLN 174

Query: 573 DVNDNEPVFKQQL-YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            VN+  PV+      + ++ ED LVG+ + ++ ATD D GL+G I Y +   + E   F 
Sbjct: 175 SVNEFPPVWTGNANLSLSLSEDILVGSKIGRLSATDRDYGLDGEIRYIILSGNGER-KFH 233

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST---VIVHIKIEDINDSPPVFE 688
           +D  +GVI  +  LDRE  +   L+  A D      S      +V IK++D+ND+ P F+
Sbjct: 234 LDEVTGVITIHAPLDRERTSYFRLRVQASDCSKKASSRRRVYAVVDIKVKDVNDNKPTFQ 293

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
                  + E + IG  I  + A D DEGPN  V YSI  G+D   F ++++ G+    L
Sbjct: 294 RKSYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSIISGNDLGFFGIDSQTGT----L 349

Query: 749 VTMVDLDYESPRKKYELV----IRA---ASPPLWNDVR-VEILVTDVNDNAPVMKDFQII 800
                LD E+    Y+L+    I A    +P   N    + I +  VN   P +     +
Sbjct: 350 RVRKSLDLETQVHVYDLIYILTISAQDQGTPRALNSTAIITIEIRSVNQFTPGLPAPSDV 409

Query: 801 FNNYKDCFPVGPFGRVPAYDADVTDK-------LQYRILSGNNANLILLNETTGSMTLSP 853
              + +  PVG        D + TDK       +++ I  GN  N   ++ +TG +T+  
Sbjct: 410 I--HPESSPVG----FEVVDWNATDKDFGADGIIRFAIFHGNEGNTFDIDSSTGKITVGK 463

Query: 854 QLNTNVPKLATMEVSVTD 871
           +LN  +     + ++++D
Sbjct: 464 KLNFTLYPRYFLHINISD 481



 Score =  165 bits (400), Expect = 6e-40
 Identities = 143/472 (30%), Positives = 215/472 (45%), Gaps = 51/472 (10%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND++P F   +    V E +  G  +  + ATD D   N +V Y I     D    
Sbjct: 64  VEDINDNAPKFASDKTMVDVYETSKIGQVITVITATDADASTNGQVSYKIASGNDD---- 119

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY----TVLVKATDQASPVSD 128
                          D FR+D ++G +    SLD E +       T++V ATD  +P   
Sbjct: 120 ---------------DYFRLDSKTGHVTLSKSLDLEILHNEGWNRTLVVIATDHGTP--- 161

Query: 129 RLSSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
           RL S A+    +   N+  P ++     ++S+ EDI V     I ++ ATD D G +  I
Sbjct: 162 RLHSNASFVFRLNSVNEFPPVWTGNANLSLSLSEDILVGSK--IGRLSATDRDYGLDGEI 219

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLL- 244
           RY I+ GN + +F +D ++G +++   LD E+   +RL ++A D    + SR     ++ 
Sbjct: 220 RYIILSGNGERKFHLDEVTGVITIHAPLDRERTSYFRLRVQASDCSKKASSRRRVYAVVD 279

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I ++DVNDN P F    +   V E   IG +I+ V A D+DEG N  +TY++     +GN
Sbjct: 280 IKVKDVNDNKPTFQRKSYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSI----ISGN 335

Query: 305 VDLP-ITIDPRSGWVYTSGQLDRETQAK-----YQLLVTATDGGDPPRSATATXXXXXXX 358
            DL    ID ++G +     LD ETQ       Y L ++A D G P    +         
Sbjct: 336 -DLGFFGIDSQTGTLRVRKSLDLETQVHVYDLIYILTISAQDQGTPRALNSTAIITIEIR 394

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416
                   +P   +V   E  P G  VV   ATD D   D  + + I  GN    F I S
Sbjct: 395 SVNQFTPGLPAPSDVIHPESSPVGFEVVDWNATDKDFGADGIIRFAIFHGNEGNTFDIDS 454

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANN 464
             G+  ITV + L+F    RY L ++ +DSG     RS    V + +T+ N+
Sbjct: 455 STGK--ITVGKKLNFTLYPRYFLHINISDSGPTSQRRSLVTKVTVRVTNLND 504



 Score = 94.7 bits (225), Expect = 1e-18
 Identities = 78/253 (30%), Positives = 115/253 (45%), Gaps = 31/253 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ P F+ + Y   V E A  G  ++T+ A+D D G N  V Y+I  ++ + L
Sbjct: 280 IKVKDVNDNKPTFQRKSYYVVVLETAQIGGAIITVHASDSDEGPNGRVTYSI--ISGNDL 337

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-----YTVLVKATDQASP 125
                              F ID ++G L  R SLD E         Y + + A DQ +P
Sbjct: 338 G-----------------FFGIDSQTGTLRVRKSLDLETQVHVYDLIYILTISAQDQGTP 380

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            +  L+STA I + I   N   P     +  +  +   S      +    ATD D GA+ 
Sbjct: 381 RA--LNSTAIITIEIRSVNQFTPGLPAPSDVIHPE---SSPVGFEVVDWNATDKDFGADG 435

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQL 243
            IR+AI  GN    F IDS +G +++ K L++     Y L I   D G  S  RS  T++
Sbjct: 436 IIRFAIFHGNEGNTFDIDSSTGKITVGKKLNFTLYPRYFLHINISDSGPTSQRRSLVTKV 495

Query: 244 LINIRDVNDNAPR 256
            + + ++NDN  R
Sbjct: 496 TVRVTNLNDNGGR 508


>SB_40275| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 1747

 Score =  196 bits (478), Expect = 2e-49
 Identities = 225/768 (29%), Positives = 332/768 (43%), Gaps = 109/768 (14%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
           LD+E   SY L + A DG     S+T  + + I+DVND  P F + L++  + EN   G 
Sbjct: 222 LDFETKSSYTLEVTATDG---KFSDTAVVTVTIQDVNDLPPVFSSPLYESRIQENTGPGA 278

Query: 275 SIVRVQAYDADEGVNAELTYTMTD--KDYTGNVDLPITIDPRSGWV----YTSGQLDRET 328
            +V V A D D   +  +++++ D  KDY     +  +  P + WV      S QLDRE 
Sbjct: 279 GVVMVTASDID---SPTISFSLDDRGKDYFQITPIRAS-GPGNVWVGDIRTGSKQLDREE 334

Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
                  V A DG     +A A               F    Y   + E++P GT V+ +
Sbjct: 335 SPVKVFTVIANDG---KHTAQAEIRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYI 391

Query: 389 TATDADE-----DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYVLTVS 442
            A D D+     + +L YE+T  +   +FSI   +  GLI      D +Q   ++ + V 
Sbjct: 392 QAVDDDDPLAGGNAKLSYELT-DSAGDKFSIDPLS--GLIKTKVTFDREQTPNKFKVRVK 448

Query: 443 ATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           ATD+G    +A V   I+++DAN++ P F    Y  SV E+AP G +VL V+ATD DVG 
Sbjct: 449 ATDAGNPRLSASVDGIIHVSDANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDVGP 508

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           NA+  + +     N+  A     F I+P  G +  + +LD E    Y +T+T  D G+P 
Sbjct: 509 NAEFEFVVVQ--GNDPHA-----FYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPP 561

Query: 561 L--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           L   +T  V I ++D NDN P F  ++Y A+++ED      V  V A D D G NG   +
Sbjct: 562 LQGDETAYVVIEILDANDNAPEFIPKIYNASVLEDVGARQPVLTVTAVDRDSGPNGNFTF 621

Query: 619 ELDPKDREEGSFVIDP-----ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
            +DP+   + +F I+P     + G+IRT   LD+E      L   +        +   + 
Sbjct: 622 AIDPRSDPDDAFTIEPNPNKCSIGIIRTRVPLDQEKTHRSTL-GYSYGRRKGVSARQFVT 680

Query: 674 HIKIEDINDSPPVFESD-CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            +K  D    P  F  D  +TF I        T+GE    DP    N  V        D 
Sbjct: 681 KLKAYD----PDAFVKDQVITFSIYNG-----TVGENFKLDPVSVTNESV--------DL 723

Query: 733 NSFSLETRQGSDKAEL-VTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNA 791
           +S+ +  R+ +   ++ +  VD     P+K +  V             V++L  DVNDNA
Sbjct: 724 HSYGVFDREAAPVWKIGIEAVDNVGPKPQKNFTYVY------------VDVL--DVNDNA 769

Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851
           P      II N Y   F  G  G+ P Y  D  D                 +E T    L
Sbjct: 770 PKDGSLLIIVNAYDGNFTGGVIGK-PYYQDDDFDG----------------DENT--YEL 810

Query: 852 SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDM-TAEQFLS 910
           + Q   + P   T  V V              VR I +E + N + V   DM     F+ 
Sbjct: 811 NSQSRKDSPSTVTSSVRVL-------------VRRIDKEAVDNGVAVEFTDMRKVGYFVG 857

Query: 911 PLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDA 958
                F D LA+ +  P  +I IFSVQ   D  G  + V F+    D+
Sbjct: 858 DYYKGFEDVLASTLGVPTGDIKIFSVQKAHD-NGLAVVVFFTVAAKDS 904



 Score =  186 bits (454), Expect = 2e-46
 Identities = 164/552 (29%), Positives = 251/552 (45%), Gaps = 41/552 (7%)

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           DG  P R  T ++  N     D +    T+  + ++   V   Y  V V A D     +A
Sbjct: 129 DGSEPHRRVTYEMKDNPNFQIDASTGMITT--KTTLDREVTPKYD-VEVTAKDGVNKESA 185

Query: 291 ELTYTMTDKDYTGNVDLPITID---PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347
            L  T+ D++    V  P +     P    +  +G+LD ET++ Y L VTATDG     S
Sbjct: 186 ILYITVVDQNDQPPVFAPKSYAISVPEDSPIVVNGKLDFETKSSYTLEVTATDG---KFS 242

Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN 407
            TA               F    YE  + E+  PG  VV +TA+D D    + + +   +
Sbjct: 243 DTAVVTVTIQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDIDSPT-ISFSL---D 298

Query: 408 TRGR--FSITSQNGRG--------LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457
            RG+  F IT     G        + T ++ LD ++    V TV A D G  +  A +++
Sbjct: 299 DRGKDYFQITPIRASGPGNVWVGDIRTGSKQLDREESPVKVFTVIAND-GKHTAQAEIRV 357

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISN 514
           N+TD N+ AP F  +PY   V E+ P GT+V+ + A D D    G NA+++Y L+    +
Sbjct: 358 NLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYELTDSAGD 417

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRE-TMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           +        F I+P +G I T    DRE T + + + V A D G P LS + D  I V D
Sbjct: 418 K--------FSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVSD 469

Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            ND++P F ++ Y  ++ E+A  G SV +V ATD DVG N    + +  +  +  +F ID
Sbjct: 470 ANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDVGPNAEFEFVV-VQGNDPHAFYID 528

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDC 691
           P +G +  +  LD E    + +     D G PP     T  V I+I D ND+ P F    
Sbjct: 529 PFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEFIPKI 588

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELV- 749
               + E+      +  + A D D GPN    ++I    D  ++F++E         ++ 
Sbjct: 589 YNASVLEDVGARQPVLTVTAVDRDSGPNGNFTFAIDPRSDPDDAFTIEPNPNKCSIGIIR 648

Query: 750 TMVDLDYESPRK 761
           T V LD E   +
Sbjct: 649 TRVPLDQEKTHR 660



 Score =  162 bits (393), Expect = 4e-39
 Identities = 176/651 (27%), Positives = 270/651 (41%), Gaps = 72/651 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND  PVF    YE+ ++E    G  V+ + A+D D         TI     D  
Sbjct: 249 VTIQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDID-------SPTISFSLDD-- 299

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             +D             +V+  D R+G+      LDRE+       V A D       + 
Sbjct: 300 RGKDYFQITPIRASGPGNVWVGDIRTGS----KQLDREESPVKVFTVIAND------GKH 349

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-SVTDNPVIAKIKATDADVGANSAIRY 189
           ++ A I VN+ D NDN P+F    Y   V+E+  S T    I  +   D   G N+ + Y
Sbjct: 350 TAQAEIRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSY 409

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +       +FSID LSG +    T D EQ    +++ ++A D G+P  S +   +I++ 
Sbjct: 410 ELTDSAGD-KFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVS 468

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D ND+ P+F    ++ SV+EN P GYS++RV A D D G NAE  + +      GN    
Sbjct: 469 DANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDVGPNAEFEFVVVQ----GNDPHA 524

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXF 366
             IDP +G V  SG LD E + +Y + +T  D G PP     TA               F
Sbjct: 525 FYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEF 584

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGR--- 420
           +P  Y   + ED     PV+T+TA D D     ++        +    F+I     +   
Sbjct: 585 IPKIYNASVLEDVGARQPVLTVTAVDRDSGPNGNFTFAIDPRSDPDDAFTIEPNPNKCSI 644

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           G+I    PLD  QE+ +  T+    S GR      +  +T    Y P             
Sbjct: 645 GIIRTRVPLD--QEKTHRSTLGY--SYGRRKGVSARQFVTKLKAYDP------------- 687

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           DA +   V+  S  +  VG N ++       ++NE+V  H              +  + D
Sbjct: 688 DAFVKDQVITFSIYNGTVGENFKLD---PVSVTNESVDLH--------------SYGVFD 730

Query: 541 RETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           RE    + + + A D  G     + T V + V+DVNDN P     L   N  +    G  
Sbjct: 731 REAAPVWKIGIEAVDNVGPKPQKNFTYVYVDVLDVNDNAPKDGSLLIIVNAYDGNFTGGV 790

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
           + +    D D        YEL+ + R++    +   S V    + +D+E+V
Sbjct: 791 IGKPYYQDDDFD-GDENTYELNSQSRKDSPSTV--TSSVRVLVRRIDKEAV 838



 Score =  147 bits (356), Expect = 1e-34
 Identities = 99/310 (31%), Positives = 151/310 (48%), Gaps = 34/310 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVT 66
           ++N+ D ND++P F    Y   V E   SGT+V+ ++A D D    G NA++ Y +    
Sbjct: 356 RVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYEL---- 411

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASP 125
                                D F ID  SG + T+ + DRE+   ++ V VKATD  +P
Sbjct: 412 ----------------TDSAGDKFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNP 455

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
              RLS++    +++ D ND+ P+F+EK Y  SV E  +      + ++ ATD DVG N+
Sbjct: 456 ---RLSASVDGIIHVSDANDHKPKFTEKFYRGSVAE--NAPPGYSVLRVTATDEDVGPNA 510

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQL 243
              + ++ GN    F ID  +G V +   LDYE+ + Y + +   D G P      T  +
Sbjct: 511 EFEFVVVQGNDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYV 570

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
           +I I D NDNAP F   ++  SV E+V     ++ V A D D G N   T+ +   D   
Sbjct: 571 VIEILDANDNAPEFIPKIYNASVLEDVGARQPVLTVTAVDRDSGPNGNFTFAI---DPRS 627

Query: 304 NVDLPITIDP 313
           + D   TI+P
Sbjct: 628 DPDDAFTIEP 637



 Score = 88.2 bits (209), Expect = 8e-17
 Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 20/232 (8%)

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           YTAS+ E+   G+TV  ++AT S     A+I+Y          +      F + P  G I
Sbjct: 2   YTASINENMETGSTVTRITATSST---GAEISYENVDTNPRAKIL-----FRVQPD-GYI 52

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN--IM 591
            T    D E  + Y +   A+D     L  T  V I+++DVND  P F   + T N  ++
Sbjct: 53  ITGDRPDYERGTTYNMQFAAKDKKT-LLYSTVKVVINIIDVNDVSPAFLLAINTRNARVL 111

Query: 592 EDALVGTSVSQVGATDADVG-LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
           E+    T V  + A D D    + R+ YE+    ++  +F ID ++G+I T   LDRE  
Sbjct: 112 ENKPAPTKVISMKAIDDDGSEPHRRVTYEM----KDNPNFQIDASTGMITTKTTLDREVT 167

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
             +D++  A DG       + I++I + D ND PPVF        + E+SPI
Sbjct: 168 PKYDVEVTAKDG---VNKESAILYITVVDQNDQPPVFAPKSYAISVPEDSPI 216



 Score = 87.0 bits (206), Expect = 2e-16
 Identities = 81/271 (29%), Positives = 112/271 (41%), Gaps = 30/271 (11%)

Query: 1089 CQG--CSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLY-- 1144
            C G  C     Y   +CE+  R+F  +S++  P L       L+ +F T+T  GLL+Y  
Sbjct: 1018 CPGFVCKCPTGYHGPLCEMTTRTFYGNSYIWLPKLMTYSLSDLEFEFMTKTADGLLVYQG 1077

Query: 1145 ---NGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI 1201
                G  N   DF+A+ L      RGG   L  S  L     ++     + DG WHTV++
Sbjct: 1078 PEREGANNGLKDFIAVVL------RGGRVELFVSLGLDPVTVKMDKGPRLDDGEWHTVQV 1131

Query: 1202 EYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHR--FLDLT 1259
                + I +I+D C   L L    D           RK     C +      R  FLD  
Sbjct: 1132 LRNMKDIEIIIDRCSTAL-LEHKPD-----GTVVENRK----SCHVYGRMLGRSVFLDGF 1181

Query: 1260 GPLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCS 1318
            GPLQIGG+ N    F  +    F GC+ +   +H   DL + +       GC +  S C 
Sbjct: 1182 GPLQIGGVSNPNMDFPDIPYTGFKGCVRNIKDNHNLYDLKNPLKVVNAPEGC-QLASACP 1240

Query: 1319 SAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348
               C N   C  L     IC C  G++GK C
Sbjct: 1241 E--CKNDGYCEPLMARDSICVCNPGYSGKHC 1269



 Score = 82.2 bits (194), Expect = 5e-15
 Identities = 70/228 (30%), Positives = 105/228 (46%), Gaps = 19/228 (8%)

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           Y   + E+   G+ V  +TAT +     + YE    N R +     Q    +IT  +P D
Sbjct: 2   YTASINENMETGSTVTRITATSST-GAEISYENVDTNPRAKILFRVQPDGYIITGDRP-D 59

Query: 431 FKQERRYVLTVSATDSGGRS-DTAMVQINITDANNYAPVFENAPYT--ASVFEDAPIGTT 487
           +++   Y +  +A D       T  V INI D N+ +P F  A  T  A V E+ P  T 
Sbjct: 60  YERGTTYNMQFAAKDKKTLLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPTK 119

Query: 488 VLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           V+ + A D D    + ++TY +            +  F I+  TG ITT   LDRE    
Sbjct: 120 VISMKAIDDDGSEPHRRVTYEMKD----------NPNFQIDASTGMITTKTTLDREVTPK 169

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           Y + VTA+DG      ++  + I+VVD ND  PVF  + Y  ++ ED+
Sbjct: 170 YDVEVTAKDG---VNKESAILYITVVDQNDQPPVFAPKSYAISVPEDS 214



 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 29/160 (18%)

Query: 11  INVLDCNDHSPVF--EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
           IN++D ND SP F   +    A V E   + T V+++KA D D G       T E+    
Sbjct: 87  INIIDVNDVSPAFLLAINTRNARVLENKPAPTKVISMKAIDDD-GSEPHRRVTYEMKD-- 143

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             NP                 F+ID  +G + T+ +LDRE   +Y V V A D  +    
Sbjct: 144 --NPN----------------FQIDASTGMITTKTTLDREVTPKYDVEVTAKDGVN---- 181

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN 168
               +A +++ ++D ND  P F+ K+Y +SV ED  +  N
Sbjct: 182 --KESAILYITVVDQNDQPPVFAPKSYAISVPEDSPIVVN 219



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 64/260 (24%), Positives = 104/260 (40%), Gaps = 14/260 (5%)

Query: 52  IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111
           I +N E   T+  +TA +    +            + +FR+    G ++T    D E+  
Sbjct: 6   INENMETGSTVTRITATSSTGAEISYENVDTNPRAKILFRVQP-DGYIITGDRPDYERGT 64

Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171
            Y +   A D+ +     L ST  + +NIID ND  P F     T +     +      +
Sbjct: 65  TYNMQFAAKDKKT----LLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPTKV 120

Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
             +KA D D   +   R           F ID+ +G ++   TLD E    Y + + A+D
Sbjct: 121 ISMKAIDDD--GSEPHRRVTYEMKDNPNFQIDASTGMITTKTTLDREVTPKYDVEVTAKD 178

Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
           G       +  L I + D ND  P F    +  SV E+ PI   +V  +  D +   +  
Sbjct: 179 G---VNKESAILYITVVDQNDQPPVFAPKSYAISVPEDSPI---VVNGK-LDFETKSSYT 231

Query: 292 LTYTMTDKDYTGNVDLPITI 311
           L  T TD  ++    + +TI
Sbjct: 232 LEVTATDGKFSDTAVVTVTI 251



 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 49/163 (30%), Positives = 72/163 (44%), Gaps = 10/163 (6%)

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
           P    I  N  LD E+ +++ L+  A DG     S T +V + I+D+ND PPVF S    
Sbjct: 211 PEDSPIVVNGKLDFETKSSYTLEVTATDGKF---SDTAVVTVTIQDVNDLPPVFSSPLYE 267

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK--AELVT- 750
             I EN+  G  +  + A D D  P        +G D      +      +    ++ T 
Sbjct: 268 SRIQENTGPGAGVVMVTASDIDS-PTISFSLDDRGKDYFQITPIRASGPGNVWVGDIRTG 326

Query: 751 MVDLDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
              LD E SP K + ++          ++RV +  TDVNDNAP
Sbjct: 327 SKQLDREESPVKVFTVIANDGKHTAQAEIRVNL--TDVNDNAP 367



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 9/85 (10%)

Query: 1477 SDVGFFEGCIQDVRIGTAQSLLNRPTV---RENVRDGCQSRADCMLSICPPYSKCVTSWD 1533
            S +G F GCI    +  A ++ + P++   R+NV DGC     C+ + C     CV +  
Sbjct: 1482 SVLGDFGGCIAGTSVNGA-NMESDPSIKVHRQNVLDGCP----CLSNFCANGGTCVDAMP 1536

Query: 1534 SSTCTCEAGRVGPQCVSACELGPCG 1558
               C C  G  GP C       P G
Sbjct: 1537 PY-CICAPGWTGPLCTIVVTAPPVG 1560



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 22/151 (14%)

Query: 1418 LSDGAWHRIEIKWLGTDISVTVDYGLRTVLM-----PMLANK----IQGQYIGK------ 1462
            L DG WH +++     DI + +D     +L       ++ N+    + G+ +G+      
Sbjct: 1121 LDDGEWHTVQVLRNMKDIEIIIDRCSTALLEHKPDGTVVENRKSCHVYGRMLGRSVFLDG 1180

Query: 1463 ---ILIGGLDTTAGLLASDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADC 1517
               + IGG+ +   +   D+ +  F+GC+++++       L  P    N  +GCQ  + C
Sbjct: 1181 FGPLQIGGV-SNPNMDFPDIPYTGFKGCVRNIKDNHNLYDLKNPLKVVNAPEGCQLASAC 1239

Query: 1518 MLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548
                   Y + + + D S C C  G  G  C
Sbjct: 1240 PECKNDGYCEPLMARD-SICVCNPGYSGKHC 1269


>SB_35963| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 864

 Score =  191 bits (466), Expect = 6e-48
 Identities = 168/607 (27%), Positives = 277/607 (45%), Gaps = 51/607 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           QI++ D N++ PVFE  +Y  ++ E     T++L ++A D DIG+N  + Y +       
Sbjct: 235 QIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARDADIGRNGGIYYYLR------ 288

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N +D           ++ +  +D +SG   T     R++            Q +  SD 
Sbjct: 289 -NTQD--FTIDAITGVIRPIRMLDFQSGQQRTLEVTARDR-GSSPKAANVNVQVTIRSDI 344

Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAI 187
                 +  +   D +  P F E  ++T+S+ ED  V  N  I  +KA D D G+ N  +
Sbjct: 345 SGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPV--NGAIQVVKANDPDAGSTNGQL 402

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQD--GGSPSRSNTTQ 242
           RY++ G N    F+IDS SG V+L   L+Y+   +     LV+ A D  G S + S +  
Sbjct: 403 RYSLSGNN---NFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVN 459

Query: 243 LLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           L I + DV  N+NAP F     + +VSE+  +G +I RV A D+D+G + ++ Y++    
Sbjct: 460 LKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDDGSDGQVVYSIIQGS 519

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             G   +  T    +G +  +  LDRE  + Y L++ A D    P+S+            
Sbjct: 520 GLGVFQVQAT----TGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVD 575

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                F    Y  +  E  P  T V  +   D D    + Y ITG ++   F I   +  
Sbjct: 576 DHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGASS---FKIVPTS-- 630

Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTA 476
           GLI    P+D   E   Y L V+AT +     +  T  V + IT      PVF+N PY  
Sbjct: 631 GLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESPPVFKNTPYAI 690

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E+      ++ V+A D+       + YS+ S           + F I+ ++G  ++ 
Sbjct: 691 SVPENQGSIANLVCVAAIDTK---GQPVIYSIES---------RGEPFGIDSKSGRFSSL 738

Query: 537 KLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           +  D ET   Y + ++A+ G  P+ ++ ++DV I++ D  D  P F Q  Y  ++ E A 
Sbjct: 739 QSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEGAS 797

Query: 596 VGTSVSQ 602
           V +++S+
Sbjct: 798 VRSTLSR 804



 Score =  179 bits (435), Expect = 3e-44
 Identities = 190/677 (28%), Positives = 298/677 (44%), Gaps = 80/677 (11%)

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIG 193
           T+ + + D N+  P F    Y   + E+ +  T    + K  A D D   +   RY I+ 
Sbjct: 121 TLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKD--RSGIDRYEIVS 178

Query: 194 GNTQMQFSIDSLSGDVS---LVKTLDYEQVR-----SYRLVIRAQDGGSPSRSNTTQLLI 245
           GN +  F  ++ +       ++K  +   VR     S  L +RA DGG      TT++ I
Sbjct: 179 GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVRANDGGG--LHGTTRIQI 236

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           +I+D N+N P F  S +  ++ E+ P+  SI+RV+A DAD G N  + Y      Y  N 
Sbjct: 237 DIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARDADIGRNGGIYY------YLRNT 290

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX- 364
               TID  +G +     LD ++  +  L VTA D G  P++A                 
Sbjct: 291 Q-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIRSDISGYPP 349

Query: 365 --------------XFMPGQ-YEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGG 406
                          F  G  + + + ED P    +  + A D D    + +L Y ++G 
Sbjct: 350 VVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQLRYSLSGN 409

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDTAMVQINI---- 459
           N    F+I S +G  ++T+   L++K    +    L V+ATD  G+S      +N+    
Sbjct: 410 NN---FAIDSTSG--VVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVNLKIEV 464

Query: 460 --TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
              D NN APVF       +V ED  +G T+  VSATDSD G + Q+ YS+   I    +
Sbjct: 465 LDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDDGSDGQVVYSI---IQGSGL 521

Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                 F +   TG +     LDRE MS Y L + A D      S    V + + DV+D+
Sbjct: 522 G----VFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDH 577

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
            P F Q +Y A   E +   T V+ V   D D+G +  + Y +        SF I P SG
Sbjct: 578 FPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSI----TGASSFKIVPTSG 631

Query: 638 VIRTNKALD-RESVATHDL--KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
           +I T   +D     +T++L   A + + GT  + +T  V+++I    +SPPVF++     
Sbjct: 632 LILTTGPIDLTTEPSTYELVVTATSTNYGT-TKRATGQVNVEITSKTESPPVFKNTPYAI 690

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
            + EN      +  + A D    P   V YSI+   +   F ++++ G       ++   
Sbjct: 691 SVPENQGSIANLVCVAAIDTKGQP---VIYSIESRGE--PFGIDSKSG----RFSSLQSF 741

Query: 755 DYESPRKKYELVIRAAS 771
           DYE+   KY + I A S
Sbjct: 742 DYET-ADKYRIQISAQS 757



 Score =  175 bits (425), Expect = 6e-43
 Identities = 201/739 (27%), Positives = 319/739 (43%), Gaps = 82/739 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-KATDQDIGKNAEVEYTIELVTAD 68
           +I V D N+  P F    Y   + E A+ GTTV  L K   +D  ++    Y  E+V+ +
Sbjct: 123 RITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKDRSGIDRY--EIVSGN 180

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
               E             Q    +   +    TR   D  + +  T+ V+A D       
Sbjct: 181 ----ERGYFVAETKTVGAQKFLVLKATN----TRIVRDPARPS-ITLTVRANDGGG---- 227

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            L  T  I ++I D N+N P F +  YTV++ ED  V  +  I +++A DAD+G N  I 
Sbjct: 228 -LHGTTRIQIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTS--ILRVRARDADIGRNGGIY 284

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y +   NTQ  F+ID+++G +  ++ LD++  +   L + A+D GS  ++    + + IR
Sbjct: 285 YYL--RNTQ-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIR 341

Query: 249 -DVND-------------NAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEG-VNAE 291
            D++              N P  +   S F  S+ E+ P+  +I  V+A D D G  N +
Sbjct: 342 SDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQ 401

Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD---RETQAKYQLLVTATD----GGDP 344
           L Y++     +GN +    ID  SG V    QL+      Q    L+VTATD     G  
Sbjct: 402 LRYSL-----SGNNN--FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGAL 454

Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402
             S                  F P Q E+ ++ED   G  +  ++ATD+D+  D ++ Y 
Sbjct: 455 SASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDDGSDGQVVYS 514

Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINIT 460
           I  G+  G F + +  G   + VA PLD ++   Y L + A D     +S    V + I 
Sbjct: 515 IIQGSGLGVFQVQATTGD--LIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQ 572

Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
           D +++ P F    Y A   E +P  T V VV   D D+G    ++YS++   S       
Sbjct: 573 DVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGASS------- 623

Query: 521 DQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNE 578
              F I P +G I T   +D  T  S Y L VTA      +    T  V + +    ++ 
Sbjct: 624 ---FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESP 680

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           PVFK   Y  ++ E+     ++  V A D        + Y ++ +      F ID  SG 
Sbjct: 681 PVFKNTPYAISVPENQGSIANLVCVAAIDTK---GQPVIYSIESRGE---PFGIDSKSGR 734

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
             + ++ D E+   + ++  A  G  P   +S+  V I I+D  D PP F        + 
Sbjct: 735 FSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVP 793

Query: 698 ENSPIGTTIGE-IRAHDPD 715
           E + + +T+   IR  D D
Sbjct: 794 EGASVRSTLSRGIRFVDED 812



 Score =  158 bits (383), Expect = 7e-38
 Identities = 161/612 (26%), Positives = 264/612 (43%), Gaps = 66/612 (10%)

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR----FYTSLFQESVSENVPIGYSIVR 278
           Y L +  +  G         L I + D N+  P     FY     E  ++   +G  + +
Sbjct: 102 YVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVG-GLEK 160

Query: 279 VQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQLLV 336
             A D D  G++     +  ++ Y       +          T+ ++ R+  +    L V
Sbjct: 161 CHAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTV 220

Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-- 394
            A DGG      T                F   +Y V + ED P  T ++ + A DAD  
Sbjct: 221 RANDGGG--LHGTTRIQIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARDADIG 278

Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
            +  ++Y +   NT+  F+I +    G+I   + LDF+  ++  L V+A D G     A 
Sbjct: 279 RNGGIYYYLR--NTQD-FTIDAIT--GVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAAN 333

Query: 455 VQINIT---DANNYAPVF---------------ENAPYTASVFEDAPIGTTVLVVSATDS 496
           V + +T   D + Y PV                E + +T S+ ED P+   + VV A D 
Sbjct: 334 VNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDP 393

Query: 497 DVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLT 550
           D G  N Q+ YSLS           +  F I+  +G +T    L+      + +   ++T
Sbjct: 394 DAGSTNGQLRYSLSG----------NNNFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVT 443

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            T R+G   +LS + +++I V+DV+DN   PVF  Q     + ED  VG ++ +V ATD+
Sbjct: 444 ATDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDS 503

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
           D G +G++ Y +  +    G F +   +G +     LDRE ++ +DL   A D  T P+S
Sbjct: 504 DDGSDGQVVYSI-IQGSGLGVFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKS 562

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
           S + V +KI+D++D  P F          E SP  T +  ++  D D G +  V YSI G
Sbjct: 563 SNLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITG 620

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR----VEILV 784
              ++SF +    G     ++T   +D  +    YELV+ A S       R    V + +
Sbjct: 621 ---ASSFKIVPTSGL----ILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEI 673

Query: 785 TDVNDNAPVMKD 796
           T   ++ PV K+
Sbjct: 674 TSKTESPPVFKN 685



 Score =  155 bits (375), Expect = 6e-37
 Identities = 149/515 (28%), Positives = 235/515 (45%), Gaps = 50/515 (9%)

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK--Q 433
           E+EP G  V +  +  ++E       + T   +  R    S++G  ++    PL +   +
Sbjct: 41  ENEPEGFRVFSFPSPPSNEIYSFFRALDTASQSALRLFDISEDG--VVVTKNPLVYTDGE 98

Query: 434 ERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
           E  YVLTV     G         ++I +TD NN+ P F    Y   + E+A  GTTV  +
Sbjct: 99  ENLYVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGL 158

Query: 492 SATDSDVGINAQIT-YSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGY 547
               ++    + I  Y + S   NE      +   +  Q   +   T  +++        
Sbjct: 159 EKCHAEDKDRSGIDRYEIVS--GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSI 216

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            LTV A DGG   L  TT ++I + D N+N PVF++  YT  I ED  V TS+ +V A D
Sbjct: 217 TLTVRANDGG--GLHGTTRIQIDIQDTNNNPPVFEKSEYTVTIGEDTPVMTSILRVRARD 274

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           AD+G NG I+Y L    R    F ID  +GVIR  + LD +S     L+  A D G+ P+
Sbjct: 275 ADIGRNGGIYYYL----RNTQDFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPK 330

Query: 668 SSTVIVHIKIE-DIN--------------DSPPVF-ESDCLTFYISENSPIGTTIGEIRA 711
           ++ V V + I  DI+              + PPVF E    T  I E+ P+   I  ++A
Sbjct: 331 AANVNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKA 390

Query: 712 HDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           +DPD G  N  + YS+ G   +N+F++++  G     L T ++      +   +LV+ A 
Sbjct: 391 NDPDAGSTNGQLRYSLSG---NNNFAIDSTSG--VVTLQTQLEYKGNPAQDVIDLVVTAT 445

Query: 771 -----SPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822
                S  L   V  ++E+L  D N+NAPV    Q+     +D        RV A D+D 
Sbjct: 446 DRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDTAVGRTIRRVSATDSDD 505

Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
               ++ Y I+ G+   +  +  TTG + ++  L+
Sbjct: 506 GSDGQVVYSIIQGSGLGVFQVQATTGDLIVAAPLD 540



 Score = 76.6 bits (180), Expect = 3e-13
 Identities = 74/294 (25%), Positives = 132/294 (44%), Gaps = 36/294 (12%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           ++  + + D +DH P F    Y A   E +   T V  +K  D D+G++  V Y+I   +
Sbjct: 565 LYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITGAS 622

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASP 125
           +                      F+I   SG +LT   +D   + + Y ++V AT     
Sbjct: 623 S----------------------FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYG 660

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            + R  +T  ++V I    ++ P F    Y +SV E+     N V   + A D       
Sbjct: 661 TTKR--ATGQVNVEITSKTESPPVFKNTPYAISVPENQGSIANLVC--VAAIDT---KGQ 713

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLL 244
            + Y+I   +    F IDS SG  S +++ DYE    YR+ I AQ G +P+  ++++ + 
Sbjct: 714 PVIYSI--ESRGEPFGIDSKSGRFSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVA 771

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           I I+D  D  P+F  S ++ SV E   +  ++ R   +  ++ ++ +L  +M +
Sbjct: 772 ITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDEDTLSTQLECSMEE 824


>SB_7364| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 408

 Score =  182 bits (443), Expect = 4e-45
 Identities = 133/421 (31%), Positives = 200/421 (47%), Gaps = 36/421 (8%)

Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
           GNT   F+I++ SG +  +  LD E    Y L + A D G P+ +++T + I++ DVNDN
Sbjct: 2   GNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDN 61

Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
            P    +       EN P G  +  + A D DEG NA + ++     Y    D   +I P
Sbjct: 62  KPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFS----GY-AVPDGKFSIKP 116

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFMPGQYE 372
            +G +     LDRE Q ++     ATD G PP  S+  +              F P  Y 
Sbjct: 117 -NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYS 175

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           V ++E+ P    +V + A++ DE  +L ++I+ G+  G F+I   N  G+I+  +PLD +
Sbjct: 176 VNISENGPSEEVIVQVNASERDE-GKLLFKISSGDPGGYFTI--HNVTGVISTRKPLDRE 232

Query: 433 QERRYVLTVSATDSGGRSDTAM--------------------VQINITDANNYAPVFENA 472
              R+ LT++A D G  S  A+                    V I + D N++APV E  
Sbjct: 233 MVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPVIEQC 292

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TG 531
               SV E+A IG+ V  ++A D D   N +ITYS+ +   N  +      F    +  G
Sbjct: 293 EQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFN--ITTQRLPFSSGSRYRG 350

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            I T  LLDRE    Y +TVTA DG   +   T ++ + + DVNDN PVF Q     ++ 
Sbjct: 351 IIITAGLLDRERQDNYNITVTASDGNHIA---TCNITVRITDVNDNSPVFNQTTMNISLH 407

Query: 592 E 592
           E
Sbjct: 408 E 408



 Score =  155 bits (376), Expect = 5e-37
 Identities = 124/410 (30%), Positives = 188/410 (45%), Gaps = 37/410 (9%)

Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463
           GNT   F+I +++G  + T+   LD +   RY+LTV A+D G    + +  V I++ D N
Sbjct: 2   GNTDNSFAINNKSG-SIYTLLH-LDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVN 59

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           +  P   N P      E+ P G+ V ++SA+D D G NA++ +S          A  D +
Sbjct: 60  DNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFS--------GYAVPDGK 111

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFK 582
           F I P  G I     LDRE  + ++    A D G P   S     +I + D NDN PVF 
Sbjct: 112 FSIKP-NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFD 170

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
              Y+ NI E+      + QV A++ D    G++ +++   D   G F I   +GVI T 
Sbjct: 171 PVHYSVNISENGPSEEVIVQVNASERD---EGKLLFKISSGD-PGGYFTIHNVTGVISTR 226

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSS-----TVI-------------VHIKIEDINDSP 684
           K LDRE V+  DL   A D G P + +     T++             V I + D ND  
Sbjct: 227 KPLDREMVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFA 286

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGS 743
           PV E       +SEN+ IG+ +  I A D D+  N  + YS+     +  +  L    GS
Sbjct: 287 PVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGS 346

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793
               ++    L     +  Y + + A+         + + +TDVNDN+PV
Sbjct: 347 RYRGIIITAGLLDRERQDNYNITVTASDGNHIATCNITVRITDVNDNSPV 396



 Score =  147 bits (355), Expect = 2e-34
 Identities = 125/423 (29%), Positives = 192/423 (45%), Gaps = 43/423 (10%)

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           GN D    I+ +SG +YT   LDRET  +Y L V A+D G+P  +++             
Sbjct: 2   GNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDN 61

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSITSQNGRG 421
                     V   E+ PPG+ V  L+A+D DE +      +G     G+FSI   NG  
Sbjct: 62  KPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGKFSI-KPNGE- 119

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASV 478
            I V   LD + + R+V    ATDSG     S      I I D N+  PVF+   Y+ ++
Sbjct: 120 -IMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNI 178

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            E+ P    ++ V+A++ D G   ++ + +SS             F I+  TG I+T K 
Sbjct: 179 SENGPSEEVIVQVNASERDEG---KLLFKISS-------GDPGGYFTIHNVTGVISTRKP 228

Query: 539 LDRETMSGYLLTVTARDGGVPS------------------LSDTTDVEISVVDVNDNEPV 580
           LDRE +S + LT+TA D G PS                  ++    V I V D ND  PV
Sbjct: 229 LDREMVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPV 288

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS---- 636
            +Q     ++ E+A +G++V+ + A D D   N +I Y +        +  +  +S    
Sbjct: 289 IEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRY 348

Query: 637 -GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
            G+I T   LDRE    +++   A DG      +T  + ++I D+ND+ PVF    +   
Sbjct: 349 RGIIITAGLLDRERQDNYNITVTASDGN---HIATCNITVRITDVNDNSPVFNQTTMNIS 405

Query: 696 ISE 698
           + E
Sbjct: 406 LHE 408



 Score =  130 bits (314), Expect = 2e-29
 Identities = 126/421 (29%), Positives = 193/421 (45%), Gaps = 50/421 (11%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F I+ +SG++ T   LDRE   RY + V A+D+  P  +  S+  TIHVN  D NDN P 
Sbjct: 8   FAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNS-STNVTIHVN--DVNDNKPN 64

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR---YAIIGGNTQMQFSIDSLS 206
            +     V   E  +     ++  + A+D D G+N+ +    YA+  G    +FSI   +
Sbjct: 65  ITNNPGVVVTRE--NTPPGSLVYILSASDLDEGSNARVAFSGYAVPDG----KFSIKP-N 117

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQES 265
           G++ +  +LD E    +     A D G P   S+     I I D NDN P F    +  +
Sbjct: 118 GEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVN 177

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           +SEN P    IV+V A + DEG   +L + ++  D  G      TI   +G + T   LD
Sbjct: 178 ISENGPSEEVIVQVNASERDEG---KLLFKISSGDPGGY----FTIHNVTGVISTRKPLD 230

Query: 326 RETQAKYQLLVTATDGGDPPR--------------SATATXXXXXXXXXXXXXXFMP--G 369
           RE  +++ L +TA D G P R              S                  F P   
Sbjct: 231 REMVSRFDLTITAEDEGRPSRMALGYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPVIE 290

Query: 370 QYE--VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ-----NG--- 419
           Q E  V ++E+   G+ V ++ A D D+ +      + GN+   F+IT+Q     +G   
Sbjct: 291 QCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNS--AFNITTQRLPFSSGSRY 348

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
           RG+I  A  LD +++  Y +TV+A+D G    T  + + ITD N+ +PVF       S+ 
Sbjct: 349 RGIIITAGLLDRERQDNYNITVTASD-GNHIATCNITVRITDVNDNSPVFNQTTMNISLH 407

Query: 480 E 480
           E
Sbjct: 408 E 408



 Score =  119 bits (287), Expect = 3e-26
 Identities = 107/351 (30%), Positives = 159/351 (45%), Gaps = 48/351 (13%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+V D ND+ P           RE    G+ V  L A+D D G NA V ++   V     
Sbjct: 53  IHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAV----- 107

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P+                F I   +G ++ R SLDRE   R+     ATD   P  +  
Sbjct: 108 -PDGK--------------FSIK-PNGEIMVRDSLDREAQNRFVFYAMATDSGQPPFN-- 149

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SS  +  + I D+NDN P F    Y+V++ E  +     VI ++ A++ D G    + + 
Sbjct: 150 SSMVSFDILIADENDNNPVFDPVHYSVNISE--NGPSEEVIVQVNASERDEG---KLLFK 204

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR------SNTTQLL 244
           I  G+    F+I +++G +S  K LD E V  + L I A+D G PSR          +LL
Sbjct: 205 ISSGDPGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVCTLLELL 264

Query: 245 IN------------IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
           ++            + D ND AP         SVSEN  IG ++  + A D D+  N ++
Sbjct: 265 VSKRVAQRGRVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKI 324

Query: 293 TYTMTDKDYTGNVD-LPITIDPR-SGWVYTSGQLDRETQAKYQLLVTATDG 341
           TY++ +  +      LP +   R  G + T+G LDRE Q  Y + VTA+DG
Sbjct: 325 TYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTASDG 375



 Score = 82.2 bits (194), Expect = 5e-15
 Identities = 68/248 (27%), Positives = 112/248 (45%), Gaps = 10/248 (4%)

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
           + SF I+  SG I T   LDRE+   + L  +A D G P  +S+  V I + D+ND+ P 
Sbjct: 5   DNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPN 64

Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
             ++       EN+P G+ +  + A D DEG NA V +S     D   FS++        
Sbjct: 65  ITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGK-FSIKPN-----G 118

Query: 747 ELVTMVDLDYESPRKK--YELVIRAASPPLWND-VRVEILVTDVNDNAPVMKDFQIIFNN 803
           E++    LD E+  +   Y +   +  PP  +  V  +IL+ D NDN PV        N 
Sbjct: 119 EIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNI 178

Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863
            ++        +V A + D   KL ++I SG+      ++  TG ++    L+  +    
Sbjct: 179 SENGPSEEVIVQVNASERD-EGKLLFKISSGDPGGYFTIHNVTGVISTRKPLDREMVSRF 237

Query: 864 TMEVSVTD 871
            + ++  D
Sbjct: 238 DLTITAED 245



 Score = 74.1 bits (174), Expect = 1e-12
 Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 52/281 (18%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D ND++PVF+   Y  ++ E   S   ++ + A+++D GK        ++ + D  
Sbjct: 157 ILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDEGK-----LLFKISSGDP- 210

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP----- 125
                              F I   +G + TR  LDRE V+R+ + + A D+  P     
Sbjct: 211 ----------------GGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGRPSRMAL 254

Query: 126 ----------VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK 175
                     VS R++    + + + D+ND  P   +    VSV E+  +     +A I 
Sbjct: 255 GYVCTLLELLVSKRVAQRGRVTIFVNDENDFAPVIEQCEQLVSVSENAHI--GSAVASIN 312

Query: 176 ATDADVGANSAIRYAIIGGNT-------QMQFSIDS-LSGDVSLVKTLDYEQVRSYRLVI 227
           A D D  +N+ I Y++  GN+       ++ FS  S   G +     LD E+  +Y + +
Sbjct: 313 AVDKDDPSNTKITYSV--GNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITV 370

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            A DG   +  N T   + I DVNDN+P F  +    S+ E
Sbjct: 371 TASDGNHIATCNIT---VRITDVNDNSPVFNQTTMNISLHE 408


>SB_18765| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 389

 Score =  175 bits (425), Expect = 6e-43
 Identities = 121/370 (32%), Positives = 177/370 (47%), Gaps = 26/370 (7%)

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
           D  SG +  +G L    +  Y ++V  TDGG P   + A                    Y
Sbjct: 16  DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------Y 69

Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQP 428
           +V + E E     V+ L   ++      H+ ++GGN        S+ S NG  L   + P
Sbjct: 70  DVSVLEGEA-NVQVMDLKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTP 122

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           LD +   +++L +S T+ G       V +N+ D N+  P+F++  +  SV E   +GT  
Sbjct: 123 LDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVF 182

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           L VSATD D G N+ +TYS+       A  + +  F IN +TGAI+  K LDRET   Y 
Sbjct: 183 LTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYT 235

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           LTV A+DGG P L+ TT V I V D NDN PV +  +   ++ E A + T V+ V A+D 
Sbjct: 236 LTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDK 295

Query: 609 DVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           D+G NGR+ Y ++      G F I D +SG I     L       + +     DGG+P  
Sbjct: 296 DIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPAL 353

Query: 668 SSTVIVHIKI 677
            S  +V I +
Sbjct: 354 KSRAMVVIDV 363



 Score =  144 bits (349), Expect = 9e-34
 Identities = 120/391 (30%), Positives = 181/391 (46%), Gaps = 34/391 (8%)

Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQIN 458
           Y I  G   G F I   +  G I++A  L + Q   Y++ V+ TD G  +    AMV I+
Sbjct: 2   YSIESG-AHGHFRIKDSSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVID 59

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLSSEISNEAV 517
           +T      P   N  Y  SV E       V+ +   +S   ++    T+  SS       
Sbjct: 60  VT------PKPRNLTYDVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDSS------- 105

Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                 F IN  T     +  LDRET + ++L ++  +GG  ++     V ++V+D+ND 
Sbjct: 106 ---GSMFSING-TNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDE 159

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
            P+F+   +  ++ E   +GT    V ATD D G N  + Y +     EEG F I+  +G
Sbjct: 160 TPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTG 218

Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
            I   K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV +   +   +S
Sbjct: 219 AISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLS 278

Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
           E + I T +  + A D D G N  + YSI+ G   + F ++    S    L  M  L Y 
Sbjct: 279 ETAEIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAISLAGM--LSY- 333

Query: 758 SPRKKYELVIR---AASPPLWNDVRVEILVT 785
           + R  Y +V+      SP L +   V I VT
Sbjct: 334 NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 364



 Score =  138 bits (335), Expect = 4e-32
 Identities = 86/262 (32%), Positives = 133/262 (50%), Gaps = 12/262 (4%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F I+G +   +    LDRE  A++ + +  T+  +     +     + VN++D ND  P
Sbjct: 108 MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 161

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G 
Sbjct: 162 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 219

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    ++ Q S+SE
Sbjct: 220 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 279

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
              I   +  V A D D G N  L Y++ +    G+  +    D  SG +  +G L    
Sbjct: 280 TAEIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFQIK---DSSSGAISLAGMLSYNQ 335

Query: 329 QAKYQLLVTATDGGDPPRSATA 350
           +  Y ++V  TDGG P   + A
Sbjct: 336 RNNYIVVVNVTDGGSPALKSRA 357



 Score =  135 bits (326), Expect = 6e-31
 Identities = 118/396 (29%), Positives = 178/396 (44%), Gaps = 34/396 (8%)

Query: 90  FRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           FRI D  SGA+     L   +   Y V+V  TD  SP    L S A + +++       P
Sbjct: 12  FRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAMVVIDVT------P 62

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
           +    TY VSV E  +   N  +  +K  ++    +    +     +  M FSI+  +  
Sbjct: 63  KPRNLTYDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLR 117

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           V     LD E    + L I   +GG  +     ++ +N+ D+ND  P F +  F  SV+E
Sbjct: 118 VGST-PLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNE 174

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
              +G   + V A D D G N+ LTY++      GN +   +I+ ++G +  + QLDRET
Sbjct: 175 IERLGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRET 230

Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
           + +Y L V A DGG+PP ++T                      +V L+E     TPV T+
Sbjct: 231 RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATV 290

Query: 389 TATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            A+D D   + RL Y I  G   G F I   +  G I++A  L + Q   Y++ V+ TD 
Sbjct: 291 IASDKDIGANGRLMYSIESG-AHGHFQI-KDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 348

Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480
           G  +    AMV I++T      P   N  Y  SV E
Sbjct: 349 GSPALKSRAMVVIDVT------PKPRNLTYDVSVLE 378



 Score =  120 bits (290), Expect = 1e-26
 Identities = 80/238 (33%), Positives = 118/238 (49%), Gaps = 26/238 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I        
Sbjct: 151 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 202

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +  F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 203 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 248

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +ST  + + + D NDN P   +    VS+ E   + D PV A + A+D D+GAN  + Y+
Sbjct: 249 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI-DTPV-ATVIASDKDIGANGRLMYS 306

Query: 191 IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           I  G     F I DS SG +SL   L Y Q  +Y +V+   DGGSP+  +   ++I++
Sbjct: 307 IESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 363



 Score =  115 bits (276), Expect = 6e-25
 Identities = 98/358 (27%), Positives = 161/358 (44%), Gaps = 23/358 (6%)

Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
           H    + +  +GAI+   +L     + Y++ V   DGG P+L     V   V+DV    P
Sbjct: 9   HGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---P 62

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
             +   Y  +++E       V  +   ++   ++G      D      GS      + + 
Sbjct: 63  KPRNLTYDVSVLEGE-ANVQVMDLKPAESHFNVSGGNFTFFD----SSGSMFSINGTNLR 117

Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
             +  LDRE+ A H L     +GGT      V V + + DIND  P+F+S      ++E 
Sbjct: 118 VGSTPLDRETAAQHILDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEI 175

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
             +GT    + A D D G N+ + YSI  G++   FS+  + G+    +     LD E+ 
Sbjct: 176 ERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET- 230

Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816
           R +Y L + A     PPL +   V I V D NDN PV++D  I  +  +      P   V
Sbjct: 231 RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATV 290

Query: 817 PAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            A D D+    +L Y I SG + +  + + ++G+++L+  L+ N      + V+VTDG
Sbjct: 291 IASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 348


>SB_44524| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 630

 Score =  173 bits (422), Expect = 1e-42
 Identities = 148/562 (26%), Positives = 248/562 (44%), Gaps = 31/562 (5%)

Query: 207 GDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
           G ++   TLD+E  R   + LVI  ++       +   + + + D ND+AP+F   L+  
Sbjct: 80  GTLTTKATLDHEDKRGNVFNLVIVRRELSRREGGSVIIVSVIVLDRNDHAPKFPKDLYNA 139

Query: 265 SVSENVPIGYSIVRVQ---AYDADEGVNAELTYTMTDKDYTG--NVDLPITIDPRSGWVY 319
            V+EN P G  ++ ++   A D D GVNA  TYT+ + +  G   VD+      +   + 
Sbjct: 140 YVAENKPAGTFVLGLEDVYAGDLDSGVNAAYTYTIVEGNKEGLFAVDVNELGGVQFLRLR 199

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
           T+  +DRE  A + L V  TD G P  S+T                F P  YE+ + E+ 
Sbjct: 200 TTAAIDREKTAFFVLTVQVTDHGKPRMSSTTQVRINILDENDCAPVFDPQIYEISVNENA 259

Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
             G+ VV + A DAD  +         +    F I S    G+++V   ++F++   + +
Sbjct: 260 AIGSSVVHVKAVDADAGSNADVYYFFTHDHDFFMINSHT--GVVSVTSHINFEKGNYFEI 317

Query: 440 TVSATDSGGRSDTA--MVQINITDANNY---------APVFENAPYTASVFEDAPIGTTV 488
            V+A D G     A  +V+I + + + +          P+F+ + Y   + ED P+ +  
Sbjct: 318 RVAAVDRGRNPHNASTLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAF 377

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           L +         +A++TY LS       +A  D  F INP++G IT  K LD ET   Y 
Sbjct: 378 LHLRIKGDVEDNHARVTYELS------PIALRD-VFAINPKSGVITLRKPLDYETRKTYS 430

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDN--EPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           + V A D    +    T++ I V DV++N   P F+      ++ +DA   T ++ V AT
Sbjct: 431 IKVIALDNRHQTFFAETEITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVSAT 490

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D G  G + Y +       G F +    GVI    +L+R+    +DL   A D    P
Sbjct: 491 DGDSGREGEVRYHI-VGGSGAGLFALHETGGVITPYGSLNRDH-KRYDLYIEARDNAKNP 548

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           +++ +   I  +  N+  P F +      + ENS    T   +   +     +  + YSI
Sbjct: 549 RTARLYALILADAKNEKRPFFFAPTQIAEVRENSEESETFVTVVRAEFKGKDSKQMRYSI 608

Query: 727 KGGDDSNSFSLETRQGSDKAEL 748
             G++   F++    G    E+
Sbjct: 609 SAGNEEGKFTISPETGECFVEI 630



 Score =  169 bits (412), Expect = 2e-41
 Identities = 143/508 (28%), Positives = 238/508 (46%), Gaps = 38/508 (7%)

Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
           +VE+ E   PGT ++TL     D      Y +   ++R  +S+      G +T    LD 
Sbjct: 37  KVEVFEGTEPGTVLLTL-----DRIPGFEY-VLQDSSRDSYSLFHITPDGTLTTKATLDH 90

Query: 432 KQERRYV--LTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           + +R  V  L +   +   R      +V + + D N++AP F    Y A V E+ P GT 
Sbjct: 91  EDKRGNVFNLVIVRRELSRREGGSVIIVSVIVLDRNDHAPKFPKDLYNAYVAENKPAGTF 150

Query: 488 VLV---VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           VL    V A D D G+NA  TY++  E + E +   D   +   Q   + T   +DRE  
Sbjct: 151 VLGLEDVYAGDLDSGVNAAYTYTIV-EGNKEGLFAVDVNELGGVQFLRLRTTAAIDREKT 209

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
           + ++LTV   D G P +S TT V I+++D ND  PVF  Q+Y  ++ E+A +G+SV  V 
Sbjct: 210 AFFVLTVQVTDHGKPRMSSTTQVRINILDENDCAPVFDPQIYEISVNENAAIGSSVVHVK 269

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           A DAD G N  ++Y       +   F+I+  +GV+     ++ E     +++  A+D G 
Sbjct: 270 AVDADAGSNADVYYFF---THDHDFFMINSHTGVVSVTSHINFEKGNYFEIRVAAVDRGR 326

Query: 665 PPQSSTVIVHIKIED---------INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
            P +++ +V I++ +         I+ SPP+F+       I E+ P+ +    +R     
Sbjct: 327 NPHNASTLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAFLHLRIKGDV 386

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772
           E  +A V Y +      + F++  + G     +     LDYE+ RK Y + + A      
Sbjct: 387 EDNHARVTYELSPIALRDVFAINPKSG----VITLRKPLDYET-RKTYSIKVIALDNRHQ 441

Query: 773 PLWNDVRVEILVTDVNDN--APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQ 828
             + +  + I VTDV++N   P  + F ++ +  +D         V A D D     +++
Sbjct: 442 TFFAETEITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVSATDGDSGREGEVR 501

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLN 856
           Y I+ G+ A L  L+ET G +T    LN
Sbjct: 502 YHIVGGSGAGLFALHETGGVITPYGSLN 529



 Score =  169 bits (410), Expect = 4e-41
 Identities = 155/565 (27%), Positives = 247/565 (43%), Gaps = 44/565 (7%)

Query: 97  GALLTRASLDRE-KVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           G L T+A+LD E K      LV    + S       S   + V ++D ND+ P+F +  Y
Sbjct: 80  GTLTTKATLDHEDKRGNVFNLVIVRRELSRREG--GSVIIVSVIVLDRNDHAPKFPKDLY 137

Query: 156 TVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSID-SLSGDVSLVK 213
              V E+       + +  + A D D G N+A  Y I+ GN +  F++D +  G V  ++
Sbjct: 138 NAYVAENKPAGTFVLGLEDVYAGDLDSGVNAAYTYTIVEGNKEGLFAVDVNELGGVQFLR 197

Query: 214 -----TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
                 +D E+   + L ++  D G P  S+TTQ+ INI D ND AP F   +++ SV+E
Sbjct: 198 LRTTAAIDREKTAFFVLTVQVTDHGKPRMSSTTQVRINILDENDCAPVFDPQIYEISVNE 257

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           N  IG S+V V+A DAD G NA++ Y  T D D+         I+  +G V  +  ++ E
Sbjct: 258 NAAIGSSVVHVKAVDADAGSNADVYYFFTHDHDF-------FMINSHTGVVSVTSHINFE 310

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXX---------XXXXXXXXFMPGQYEVELAED 378
               +++ V A D G  P +A+                         F   +Y V++ ED
Sbjct: 311 KGNYFEIRVAAVDRGRNPHNASTLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIRED 370

Query: 379 EPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
            P  +  + L      EDN  R+ YE++    R  F+I  ++  G+IT+ +PLD++  + 
Sbjct: 371 LPVNSAFLHLRIKGDVEDNHARVTYELSPIALRDVFAINPKS--GVITLRKPLDYETRKT 428

Query: 437 YVLTVSATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
           Y + V A D+  ++  A  +I I     D N + P FE+      + +DA   T +  VS
Sbjct: 429 YSIKVIALDNRHQTFFAETEITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVS 488

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
           ATD D G   ++ Y +         A H+   VI P       +K  D        L + 
Sbjct: 489 ATDGDSGREGEVRYHIVGGSGAGLFALHETGGVITPYGSLNRDHKRYD--------LYIE 540

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           ARD      +      I     N+  P F      A + E++    +   V   +     
Sbjct: 541 ARDNAKNPRTARLYALILADAKNEKRPFFFAPTQIAEVRENSEESETFVTVVRAEFKGKD 600

Query: 613 NGRIHYELDPKDREEGSFVIDPASG 637
           + ++ Y +     EEG F I P +G
Sbjct: 601 SKQMRYSIS-AGNEEGKFTISPETG 624



 Score =  158 bits (384), Expect = 5e-38
 Identities = 156/537 (29%), Positives = 250/537 (46%), Gaps = 52/537 (9%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIELVTADT 69
           VLD NDH+P F    Y A V E   +GT VL L+   A D D G NA   YTI  V    
Sbjct: 122 VLDRNDHAPKFPKDLYNAYVAENKPAGTFVLGLEDVYAGDLDSGVNAAYTYTI--VEG-- 177

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N E            VQ +         L T A++DREK A + + V+ TD   P   R
Sbjct: 178 -NKEGLFAVDVNELGGVQFL--------RLRTTAAIDREKTAFFVLTVQVTDHGKP---R 225

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           +SST  + +NI+D+ND  P F  + Y +SV+E+ ++  +  +  +KA DAD G+N+ + Y
Sbjct: 226 MSSTTQVRINILDENDCAPVFDPQIYEISVNENAAIGSS--VVHVKAVDADAGSNADVYY 283

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
                +    F I+S +G VS+   +++E+   + + + A D G    + +T + I + +
Sbjct: 284 FFT--HDHDFFMINSHTGVVSVTSHINFEKGNYFEIRVAAVDRGRNPHNASTLVKIRLLE 341

Query: 250 VN--DNAPRFYTS--LFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           V+     PR +TS  +FQ S     + E++P+  + + ++     E  +A +TY ++   
Sbjct: 342 VDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAFLHLRIKGDVEDNHARVTYELSP-- 399

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA--TXXXXXXX 358
                D+   I+P+SG +     LD ET+  Y + V A D       A    T       
Sbjct: 400 -IALRDV-FAINPKSGVITLRKPLDYETRKTYSIKVIALDNRHQTFFAETEITIEVTDVD 457

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416
                  F        L +D    T + T++ATD D   +  + Y I GG+  G F++  
Sbjct: 458 ENYFTPEFESFTVLGHLPQDADARTLIATVSATDGDSGREGEVRYHIVGGSGAGLFAL-H 516

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA-MVQINITDANNYAPVFENAP-Y 474
           + G G+IT    L+ +  +RY L + A D+     TA +  + + DA N    F  AP  
Sbjct: 517 ETG-GVITPYGSLN-RDHKRYDLYIEARDNAKNPRTARLYALILADAKNEKRPFFFAPTQ 574

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
            A V E++    T + V   +     + Q+ YS+S+   NE     + +F I+P+TG
Sbjct: 575 IAEVRENSEESETFVTVVRAEFKGKDSKQMRYSISA--GNE-----EGKFTISPETG 624



 Score =  116 bits (280), Expect = 2e-25
 Identities = 110/428 (25%), Positives = 182/428 (42%), Gaps = 42/428 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +IN+LD ND +PVF+ Q YE SV E A+ G++V+ +KA D D G NA+V Y     T D 
Sbjct: 233 RINILDENDCAPVFDPQIYEISVNENAAIGSSVVHVKAVDADAGSNADVYY---FFTHD- 288

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             D F I+  +G +   + ++ EK   + + V A D+     + 
Sbjct: 289 -----------------HDFFMINSHTGVVSVTSHINFEKGNYFEIRVAAVDRGRNPHNA 331

Query: 130 LSSTATIHVNIIDD-------NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            S+   I +  +D        + + P F    Y V + ED+ V    +  +IK    DV 
Sbjct: 332 -STLVKIRLLEVDGFPPPPRIHTSPPMFQLSEYYVKIREDLPVNSAFLHLRIKG---DVE 387

Query: 183 ANSA-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            N A + Y +     +  F+I+  SG ++L K LDYE  ++Y + + A D    +    T
Sbjct: 388 DNHARVTYELSPIALRDVFAINPKSGVITLRKPLDYETRKTYSIKVIALDNRHQTFFAET 447

Query: 242 QLLINIRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           ++ I + DV++N   P F +      + ++      I  V A D D G   E+ Y +   
Sbjct: 448 EITIEVTDVDENYFTPEFESFTVLGHLPQDADARTLIATVSATDGDSGREGEVRYHIVGG 507

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
              G   L  T     G +   G L+R+   +Y L + A D    PR+A           
Sbjct: 508 SGAGLFALHET----GGVITPYGSLNRD-HKRYDLYIEARDNAKNPRTARLYALILADAK 562

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD--ADEDNRLHYEITGGNTRGRFSITSQ 417
                 F       E+ E+       VT+   +    +  ++ Y I+ GN  G+F+I+ +
Sbjct: 563 NEKRPFFFAPTQIAEVRENSEESETFVTVVRAEFKGKDSKQMRYSISAGNEEGKFTISPE 622

Query: 418 NGRGLITV 425
            G   + +
Sbjct: 623 TGECFVEI 630


>SB_33995| Best HMM Match : Cadherin (HMM E-Value=3e-39)
          Length = 632

 Score =  165 bits (401), Expect = 5e-40
 Identities = 168/615 (27%), Positives = 264/615 (42%), Gaps = 61/615 (9%)

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           +S    LD E+V  Y L +RA+  G+P S S+  Q+++ + D+NDN P F  +     + 
Sbjct: 3   ISTTSRLDRERVDRYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYIR 62

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--- 324
           EN     +++ + A D D G+N+++TYT+   +  G   +  T+   S  +     L   
Sbjct: 63  ENQGTIPNLLCLIASDKDIGLNSDITYTIESGNDDGLFAIHPTLGILSEIIRLREDLGAR 122

Query: 325 --DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
             D   +++Y  L        P  S   T                 G   V + ED  PG
Sbjct: 123 VDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITDEDARHKFGGDNPVSVEEDAEPG 182

Query: 383 TPVVTLTATDADEDNRLHYEIT----GGNTRGRFSI-TSQNGRGLITVAQPLDFKQERRY 437
             +  + +TD D      +  T      +    FS  T + G  LI +   L++ +  +Y
Sbjct: 183 RTLTIIDSTDEDAGKSGQFVCTIDDVDSDVMDMFSFHTVRQGCALI-LYNHLEYSRRSQY 241

Query: 438 VLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
              V A+D        S TA V + + D NN  P+F+ + Y  ++ E +PIGT +L V+A
Sbjct: 242 TFKVRASDQADAVQQLSTTANVIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTA 301

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D D G             SN  V  H  Q+         + NK         Y  TVTA
Sbjct: 302 EDLDSG-------------SNADVKDHYLQY-------QASRNKK--------YSFTVTA 333

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            D G PS S    V +S+   +D+ PVF++  Y   I E+  +   + +V A     G  
Sbjct: 334 FDQGKPSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAG 393

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID----GGTPPQSS 669
           G + Y L   D  +  F +D  +G +   K LD E VA++ L+  A+        P   +
Sbjct: 394 GELRYYLVGGD-PQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPA 452

Query: 670 TVIVHIKIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
              V I + DIND+ P F    + L   I +  P GTT+ ++ A+D D G +A+V Y ++
Sbjct: 453 EATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLE 512

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWN-DVRVEILV 784
              DS  F++  + G  K    T  +L +   R  Y  V+ A  ++PP       V + V
Sbjct: 513 NA-DSFPFTITPQTGVIK----TTAELRH-FERDFYAFVVTATDSTPPFHKVTANVNVHV 566

Query: 785 TDVNDNAPVMKDFQI 799
           TD     PV    +I
Sbjct: 567 TDAR-TPPVFTKVRI 580



 Score =  161 bits (391), Expect = 7e-39
 Identities = 165/608 (27%), Positives = 249/608 (40%), Gaps = 68/608 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND+ PVF    +   +RE   +   +L L A+D+DIG N+++ YTIE       
Sbjct: 40  VMVTDMNDNRPVFANTNHTVYIRENQGTIPNLLCLIASDKDIGLNSDITYTIES------ 93

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             +D           + ++ R+    GA +     D  K +RY  L +      P S ++
Sbjct: 94  GNDDGLFAIHPTLGILSEIIRLREDLGARVD----DTSKRSRYPELEQYCALNVPDSSKI 149

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +   I V  I D D   +F      VSV+ED        +  I +TD D G +      
Sbjct: 150 RTI--IAVLEITDEDARHKFGGDN-PVSVEEDAE--PGRTLTIIDSTDEDAGKSGQFVCT 204

Query: 191 I--IGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLL 244
           I  +  +    FS  ++    +L+    L+Y +   Y   +RA D     +  S T  ++
Sbjct: 205 IDDVDSDVMDMFSFHTVRQGCALILYNHLEYSRRSQYTFKVRASDQADAVQQLSTTANVI 264

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + + D N+N P F  S +  ++ E  PIG  ++RV A D D G NA++      KD+   
Sbjct: 265 VRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADV------KDH--- 315

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                         Y   Q  R    KY   VTA D G P RS+ AT             
Sbjct: 316 --------------YLQYQASRNK--KYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPP 359

Query: 365 XFMPGQYEVELAEDEP--PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
            F    YE  + E+     G   V   A        L Y + GG+ + +F++    G   
Sbjct: 360 VFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVGGDPQSQFNVDRLTGE-- 417

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDT------AMVQINITDANNYAPVFE--NAPY 474
           +++ +PLD+++   Y L + A     R +       A V I +TD N+ AP F     P 
Sbjct: 418 LSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPREPL 477

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             S+ +  P GTTV  V+A D D G +A + Y L +  S          F I PQTG I 
Sbjct: 478 VTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENADSFP--------FTITPQTGVIK 529

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMED 593
           T   L       Y   VTA D   P    T +V + V D     PVF K ++    I   
Sbjct: 530 TTAELRHFERDFYAFVVTATDSTPPFHKVTANVNVHVTDAR-TPPVFTKVRIAVITITTT 588

Query: 594 ALVGTSVS 601
             + T+++
Sbjct: 589 ITITTTIT 596



 Score =  147 bits (355), Expect = 2e-34
 Identities = 158/607 (26%), Positives = 253/607 (41%), Gaps = 56/607 (9%)

Query: 101 TRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVD 160
           T + LDRE+V RY + V+A    +P S  +SS A + V + D NDN P F+   +TV + 
Sbjct: 5   TTSRLDRERVDRYALEVRARVNGAPQS--MSSPAQVVVMVTDMNDNRPVFANTNHTVYIR 62

Query: 161 EDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS--------LV 212
           E+     N  +  + A+D D+G NS I Y I  GN    F+I    G +S        L 
Sbjct: 63  ENQGTIPN--LLCLIASDKDIGLNSDITYTIESGNDDGLFAIHPTLGILSEIIRLREDLG 120

Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVP 271
             +D    RS    +      +   S+  + +I + ++ D   R  +      SV E+  
Sbjct: 121 ARVDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITDEDARHKFGGDNPVSVEEDAE 180

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQA 330
            G ++  + + D D G + +   T+ D D +  +D+      R G  +     L+   ++
Sbjct: 181 PGRTLTIIDSTDEDAGKSGQFVCTIDDVD-SDVMDMFSFHTVRQGCALILYNHLEYSRRS 239

Query: 331 KYQLLVTATDGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
           +Y   V A+D  D  +  S TA               F    Y V L E  P GT ++ +
Sbjct: 240 QYTFKVRASDQADAVQQLSTTANVIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRV 299

Query: 389 TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG- 447
           TA D D         +G N   +                     + ++Y  TV+A D G 
Sbjct: 300 TAEDLD---------SGSNADVKDHYLQYQA------------SRNKKYSFTVTAFDQGK 338

Query: 448 -GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
             RS  A V ++I   ++  PVF  + Y   + E+  +   ++ V A  +  G   ++ Y
Sbjct: 339 PSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRY 398

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD----GGVPSLS 562
            L              QF ++  TG ++  K LD E ++ Y L + A        +P L 
Sbjct: 399 YLVG-------GDPQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELP 451

Query: 563 DTTDVEISVVDVNDNEPVF--KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
               V I+V D+NDN P F   ++    +I +    GT+V++V A D D G +  + Y L
Sbjct: 452 AEATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGL 511

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
           +  D     F I P +GVI+T   L       +     A D   P    T  V++ + D 
Sbjct: 512 ENAD--SFPFTITPQTGVIKTTAELRHFERDFYAFVVTATDSTPPFHKVTANVNVHVTDA 569

Query: 681 NDSPPVF 687
             +PPVF
Sbjct: 570 R-TPPVF 575



 Score =  121 bits (292), Expect = 7e-27
 Identities = 132/496 (26%), Positives = 219/496 (44%), Gaps = 62/496 (12%)

Query: 31  SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVF 90
           SV E A  G T+  + +TD+D GK+ +   TI+ V +D                 V D+F
Sbjct: 174 SVEEDAEPGRTLTIIDSTDEDAGKSGQFVCTIDDVDSD-----------------VMDMF 216

Query: 91  RIDG-RSG-ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
                R G AL+    L+  + ++YT  V+A+DQA  V  +LS+TA + V ++D N+N P
Sbjct: 217 SFHTVRQGCALILYNHLEYSRRSQYTFKVRASDQADAVQ-QLSTTANVIVRVLDGNNNDP 275

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            F + +Y V++ E   +     + ++ A D D G+N+ ++   +    Q Q S +     
Sbjct: 276 IFQQSSYWVALPEGSPIGTE--LLRVTAEDLDSGSNADVKDHYL----QYQASRN----- 324

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
                       + Y   + A D G PSRS+   + ++I   +D+ P F  S +++ + E
Sbjct: 325 ------------KKYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPE 372

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
           N  +   IVRV+A     G   EL Y +      G+      +D  +G +     LD E 
Sbjct: 373 NFALKRGIVRVEALANGGGAGGELRYYLVG----GDPQSQFNVDRLTGELSLKKPLDYEK 428

Query: 329 QAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEV-ELAEDEPPG 382
            A Y+L + A         P   A AT              F +P +  V  + +  P G
Sbjct: 429 VASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAG 488

Query: 383 TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           T V  +TA D D  +   + Y +   ++   F+IT Q G  + T A+   F+++  Y   
Sbjct: 489 TTVTKVTAYDQDSGSHALVKYGLENADS-FPFTITPQTG-VIKTTAELRHFERD-FYAFV 545

Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA-SVFEDAPIGTTVLVVSATDSD 497
           V+ATDS       TA V +++TDA    PVF        ++     I TT+ + +     
Sbjct: 546 VTATDSTPPFHKVTANVNVHVTDART-PPVFTKVRIAVITITTTITITTTITITTTITIT 604

Query: 498 VGINAQITYSLSSEIS 513
           + I   IT +++  I+
Sbjct: 605 ITITITITITITITIT 620



 Score = 94.3 bits (224), Expect = 1e-18
 Identities = 88/324 (27%), Positives = 151/324 (46%), Gaps = 30/324 (9%)

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASV 478
           +I+    LD ++  RY L V A  +G     S  A V + +TD N+  PVF N  +T  +
Sbjct: 2   VISTTSRLDRERVDRYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYI 61

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            E+      +L + A+D D+G+N+ ITY++ S        + D  F I+P  G I +  +
Sbjct: 62  RENQGTIPNLLCLIASDKDIGLNSDITYTIES-------GNDDGLFAIHPTLG-ILSEII 113

Query: 539 LDRETMSGYLLTVTARDGGVPSLS--------DTTDVE--ISVVDVNDNEPVFK-QQLYT 587
             RE + G  +  T++    P L         D++ +   I+V+++ D +   K      
Sbjct: 114 RLREDL-GARVDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITDEDARHKFGGDNP 172

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSF--VIDPASGVIRTN 642
            ++ EDA  G +++ + +TD D G +G+    +D  D    +  SF  V    + ++  +
Sbjct: 173 VSVEEDAEPGRTLTIIDSTDEDAGKSGQFVCTIDDVDSDVMDMFSFHTVRQGCALILYNH 232

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
               R S  T  ++A          S+T  V +++ D N++ P+F+       + E SPI
Sbjct: 233 LEYSRRSQYTFKVRASDQADAVQQLSTTANVIVRVLDGNNNDPIFQQSSYWVALPEGSPI 292

Query: 703 GTTIGEIRAHDPDEGPNAVV--HY 724
           GT +  + A D D G NA V  HY
Sbjct: 293 GTELLRVTAEDLDSGSNADVKDHY 316



 Score = 59.3 bits (137), Expect = 4e-08
 Identities = 47/160 (29%), Positives = 79/160 (49%), Gaps = 9/160 (5%)

Query: 638 VIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
           VI T   LDRE V  + L+  A ++G     SS   V + + D+ND+ PVF +   T YI
Sbjct: 2   VISTTSRLDRERVDRYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYI 61

Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD--- 753
            EN      +  + A D D G N+ + Y+I+ G+D   F++    G   +E++ + +   
Sbjct: 62  RENQGTIPNLLCLIASDKDIGLNSDITYTIESGNDDGLFAIHPTLGI-LSEIIRLREDLG 120

Query: 754 --LDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVND 789
             +D  S R +Y  + +  A + P  + +R  I V ++ D
Sbjct: 121 ARVDDTSKRSRYPELEQYCALNVPDSSKIRTIIAVLEITD 160



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 762 KYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817
           +Y L +RA    A   + +  +V ++VTD+NDN PV  +        ++   +     + 
Sbjct: 16  RYALEVRARVNGAPQSMSSPAQVVVMVTDMNDNRPVFANTNHTVYIRENQGTIPNLLCLI 75

Query: 818 AYDADV--TDKLQYRILSGNNANLILLNETTGSMT 850
           A D D+     + Y I SGN+  L  ++ T G ++
Sbjct: 76  ASDKDIGLNSDITYTIESGNDDGLFAIHPTLGILS 110


>SB_39408| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 2389

 Score =  165 bits (400), Expect = 6e-40
 Identities = 115/346 (33%), Positives = 169/346 (48%), Gaps = 30/346 (8%)

Query: 463  NNYAPVFE--NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            N++AP F   N  Y A++ E+   GT VL VSA D D G    + +++ S        + 
Sbjct: 2040 NDFAPEFVPINPNYQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIYS-------GNT 2092

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNE 578
            D  F I+ ++G I T + LDRE +S Y LT+ ARD         TD  +SV+  DVNDN 
Sbjct: 2093 DNSFAIDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNS 2152

Query: 579  PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
            PVF    Y A + E A VG ++ +  ATD D G N R+HY +     E+G F I+  +G 
Sbjct: 2153 PVFSHDEYRALVKETARVGEAIIRARATDRDAGTNARLHYTI-TSGNEQGLFAINDETGD 2211

Query: 639  IRTNKALDRESVA----THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE---SDC 691
            +   K LD E  A     + L     D G+PP+ ++  VHI++  +N+  P+F    S  
Sbjct: 2212 VTVAKPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRN 2271

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
            LT     +  +G  + ++ A D D G    V Y+I  G+ +  F ++         +  +
Sbjct: 2272 LTIREHLDVGLGLALIDLDAKDKDYGIQGHVSYAIYSGNQAGMFRVDA-----NGTVYLL 2326

Query: 752  VDLDYESPRKKYELVIRAASPPLWN-----DVRVEILVTDVNDNAP 792
              LDY +    Y LVIRA            D  + +LV D+NDNAP
Sbjct: 2327 GTLDY-ARAPSYRLVIRATDGGAKEMRKHADFTLTVLVEDINDNAP 2371



 Score =  157 bits (382), Expect = 9e-38
 Identities = 111/335 (33%), Positives = 168/335 (50%), Gaps = 36/335 (10%)

Query: 17   NDHSPVFEM--QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            ND +P F      Y+A++ E  ++GT VLT+ A D D G   +V +TI     D      
Sbjct: 2040 NDFAPEFVPINPNYQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIYSGNTD------ 2093

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                         + F ID RSG + TR +LDRE ++ Y + ++A D A     R +  A
Sbjct: 2094 -------------NSFAIDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTD-A 2139

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
             + V + D NDN P FS   Y   V E   V +   I + +ATD D G N+ + Y I  G
Sbjct: 2140 LVSVIVSDVNDNSPVFSHDEYRALVKETARVGE--AIIRARATDRDAGTNARLHYTITSG 2197

Query: 195  NTQMQFSIDSLSGDVSLVKTLDYEQ----VRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            N Q  F+I+  +GDV++ K LD E       +YRL +   D GSP R N+T + I +  V
Sbjct: 2198 NEQGLFAINDETGDVTVAKPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPV 2257

Query: 251  NDNAPRFYTSLFQE-SVSE--NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            N+ +P F   + +  ++ E  +V +G +++ + A D D G+   ++Y +    Y+GN   
Sbjct: 2258 NEFSPIFRRGVSRNLTIREHLDVGLGLALIDLDAKDKDYGIQGHVSYAI----YSGNQAG 2313

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
               +D  +G VY  G LD      Y+L++ ATDGG
Sbjct: 2314 MFRVD-ANGTVYLLGTLDYARAPSYRLVIRATDGG 2347



 Score =  143 bits (346), Expect = 2e-33
 Identities = 109/347 (31%), Positives = 170/347 (48%), Gaps = 26/347 (7%)

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y+  L E+   GT V+T++A D D+ ++  + + I  GNT   F+I  ++G  +I   + 
Sbjct: 2053 YQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIYSGNTDNSFAIDDRSG--VIKTRRT 2110

Query: 429  LDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            LD +    Y LT+ A D       R   A+V + ++D N+ +PVF +  Y A V E A +
Sbjct: 2111 LDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNSPVFSHDEYRALVKETARV 2170

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE-- 542
            G  ++   ATD D G NA++ Y+++S   NE        F IN +TG +T  K LD E  
Sbjct: 2171 GEAIIRARATDRDAGTNARLHYTITS--GNE-----QGLFAINDETGDVTVAKPLDLEDG 2223

Query: 543  --TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL-YTANIME--DALVG 597
              T   Y L V   D G P   ++T V I V  VN+  P+F++ +     I E  D  +G
Sbjct: 2224 ALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRNLTIREHLDVGLG 2283

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             ++  + A D D G+ G + Y +     + G F +D A+G +     LD     ++ L  
Sbjct: 2284 LALIDLDAKDKDYGIQGHVSYAI-YSGNQAGMFRVD-ANGTVYLLGTLDYARAPSYRLVI 2341

Query: 658  VAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
             A DGG     + +   + + +EDIND+ P F SD     + E S I
Sbjct: 2342 RATDGGAKEMRKHADFTLTVLVEDINDNAPKFASDKTMVDVYETSKI 2388



 Score =  136 bits (328), Expect = 3e-31
 Identities = 107/358 (29%), Positives = 157/358 (43%), Gaps = 26/358 (7%)

Query: 144  NDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201
            ND  P+F      Y  ++ E+   T    +  + A D D G+   + + I  GNT   F+
Sbjct: 2040 NDFAPEFVPINPNYQATLLEN--TTTGTQVLTVSAVDHDKGSQGDVFFTIYSGNTDNSFA 2097

Query: 202  IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN--IRDVNDNAPRFYT 259
            ID  SG +   +TLD E +  Y L IRA+D     +   T  L++  + DVNDN+P F  
Sbjct: 2098 IDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNSPVFSH 2157

Query: 260  SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
              ++  V E   +G +I+R +A D D G NA L YT+T    +GN      I+  +G V 
Sbjct: 2158 DEYRALVKETARVGEAIIRARATDRDAGTNARLHYTIT----SGNEQGLFAINDETGDVT 2213

Query: 320  TSGQLDRE----TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG-QYEVE 374
             +  LD E    T   Y+L V  TD G PPR  + T              F  G    + 
Sbjct: 2214 VAKPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRNLT 2273

Query: 375  LAE--DEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            + E  D   G  ++ L A D D   + H  Y I  GN  G F +   +  G + +   LD
Sbjct: 2274 IREHLDVGLGLALIDLDAKDKDYGIQGHVSYAIYSGNQAGMFRV---DANGTVYLLGTLD 2330

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDAPI 484
            + +   Y L + ATD G +         +T    D N+ AP F +      V+E + I
Sbjct: 2331 YARAPSYRLVIRATDGGAKEMRKHADFTLTVLVEDINDNAPKFASDKTMVDVYETSKI 2388



 Score =  120 bits (290), Expect = 1e-26
 Identities = 89/263 (33%), Positives = 124/263 (47%), Gaps = 22/263 (8%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D ND+SPVF   +Y A V+E A  G  ++  +ATD+D G NA + YTI      T   
Sbjct: 2145 VSDVNDNSPVFSHDEYRALVKETARVGEAIIRARATDRDAGTNARLHYTI------TSGN 2198

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
            E            V     +D   GAL + A         Y + V  TDQ SP   R +S
Sbjct: 2199 EQGLFAINDETGDVTVAKPLDLEDGALTSLA---------YRLGVYVTDQGSP--PRGNS 2247

Query: 133  TATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            T T+H+ +   N+  P F    +  +++ E + V     +  + A D D G    + YAI
Sbjct: 2248 T-TVHIQVTPVNEFSPIFRRGVSRNLTIREHLDVGLGLALIDLDAKDKDYGIQGHVSYAI 2306

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LLINIRD 249
              GN    F +D+ +G V L+ TLDY +  SYRLVIRA DGG+          L + + D
Sbjct: 2307 YSGNQAGMFRVDA-NGTVYLLGTLDYARAPSYRLVIRATDGGAKEMRKHADFTLTVLVED 2365

Query: 250  VNDNAPRFYTSLFQESVSENVPI 272
            +NDNAP+F +      V E   I
Sbjct: 2366 INDNAPKFASDKTMVDVYETSKI 2388



 Score =  115 bits (276), Expect = 6e-25
 Identities = 95/334 (28%), Positives = 150/334 (44%), Gaps = 22/334 (6%)

Query: 574  VNDNEPVFK--QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            VND  P F      Y A ++E+   GT V  V A D D G  G + + +      + SF 
Sbjct: 2039 VNDFAPEFVPINPNYQATLLENTTTGTQVLTVSAVDHDKGSQGDVFFTIY-SGNTDNSFA 2097

Query: 632  IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFES 689
            ID  SGVI+T + LDRE ++ ++L   A D     +   +  +V + + D+ND+ PVF  
Sbjct: 2098 IDDRSGVIKTRRTLDREMISIYELTIRARDDAEAGKVRFTDALVSVIVSDVNDNSPVFSH 2157

Query: 690  DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
            D     + E + +G  I   RA D D G NA +HY+I  G++   F++    G     + 
Sbjct: 2158 DEYRALVKETARVGEAIIRARATDRDAGTNARLHYTITSGNEQGLFAINDETGD--VTVA 2215

Query: 750  TMVDL-DYESPRKKYEL---VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805
              +DL D       Y L   V    SPP  N   V I VT VN+ +P+ +         +
Sbjct: 2216 KPLDLEDGALTSLAYRLGVYVTDQGSPPRGNSTTVHIQVTPVNEFSPIFRRGVSRNLTIR 2275

Query: 806  DCFPVGPFGRVPAYDADVTDK-------LQYRILSGNNANLILLNETTGSMTLSPQLNTN 858
            +   VG  G +   D D  DK       + Y I SGN A +  + +  G++ L   L+  
Sbjct: 2276 EHLDVG-LG-LALIDLDAKDKDYGIQGHVSYAIYSGNQAGMFRV-DANGTVYLLGTLDYA 2332

Query: 859  VPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEM 891
                  + +  TD G  E++     ++ ++ E++
Sbjct: 2333 RAPSYRLVIRATDGGAKEMRKHADFTLTVLVEDI 2366


>SB_34907| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 697

 Score =  162 bits (393), Expect = 4e-39
 Identities = 162/563 (28%), Positives = 247/563 (43%), Gaps = 67/563 (11%)

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIG 193
           T+ + + D N+  P F    Y   + E+ +  T    + K  A D D   +   RY I+ 
Sbjct: 117 TLRITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGLEKCHAEDKD--RSGIDRYEIVS 174

Query: 194 GNTQMQFSIDSLSGDVS---LVKTLDYEQVR-----SYRLVIRAQDGGSPSRSNTTQLLI 245
           GN +  F  ++ +       ++K  +   VR     S  L +RA DGG      TT++ I
Sbjct: 175 GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVRANDGGG--LHGTTRIQI 232

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           +I+D N+N P F  S +  +V E+ P+  SI+RV+A DAD G N  + Y      Y  N 
Sbjct: 233 DIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYY------YLRNT 286

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX----------- 354
               TID  +G +     LD ++  +  L VTA D G  P++A                 
Sbjct: 287 Q-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIRSDISGYPP 345

Query: 355 ----XXXXXXXXXXXFMPG-QYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGG 406
                          F  G  + + + ED P    +  + A D D    + +L Y ++G 
Sbjct: 346 VVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQLRYSLSGN 405

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDTAMVQINI---- 459
           N    F+I S +  G++T+   L++K    +    L V+ATD  G+S      +N+    
Sbjct: 406 N---NFAIDSTS--GVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVNLKIEV 460

Query: 460 --TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
              D NN APVF       +V ED+ +G T+  VSATDSD G + Q+ YS+   I    +
Sbjct: 461 LDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSI---IQGSGL 517

Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                 F +   TG +     LDRE MS Y L + A D      S    V + + DV+D+
Sbjct: 518 G----VFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDH 573

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
            P F Q +Y A   E +   T V+ V   D D+G +  + Y +        SF I P SG
Sbjct: 574 FPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSI----TGASSFKIVPTSG 627

Query: 638 VIRTNKALD-RESVATHDLKAVA 659
           +I T   +D     +T++L   A
Sbjct: 628 LILTTGPIDLTTEPSTYELVVTA 650



 Score =  156 bits (378), Expect = 3e-37
 Identities = 156/582 (26%), Positives = 259/582 (44%), Gaps = 60/582 (10%)

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
           Y L +  +  G         L I + D N+  P F   L+   ++E    G ++  ++  
Sbjct: 98  YVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGLEKC 157

Query: 283 DADEGVNAEL-TYTMTDKDYTGN-VDLPITIDPRSGWVY--TSGQLDRE-TQAKYQLLVT 337
            A++   + +  Y +   +  G  V    T+  +   V   T+ ++ R+  +    L V 
Sbjct: 158 HAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVR 217

Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--E 395
           A DGG      T                F   +Y V + ED P  T ++ + A DAD   
Sbjct: 218 ANDGGG--LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGR 275

Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455
           +  ++Y +   NT+  F+I +    G+I   + LDF+  ++  L V+A D G     A V
Sbjct: 276 NGGIYYYLR--NTQD-FTIDAIT--GVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANV 330

Query: 456 QINIT---DANNYAPVF---------------ENAPYTASVFEDAPIGTTVLVVSATDSD 497
            + +T   D + Y PV                E + +T S+ ED P+   + VV A D D
Sbjct: 331 NVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPD 390

Query: 498 VG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLTV 551
            G  N Q+ YSLS           +  F I+  +G +T    L+      + +   ++T 
Sbjct: 391 AGSTNGQLRYSLSG----------NNNFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTA 440

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
           T R+G   +LS + +++I V+DV+DN   PVF  Q     + ED+ VG ++ +V ATD+D
Sbjct: 441 TDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSD 500

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
            G +G++ Y +  +    G F +   +G +     LDRE ++ +DL   A D  T P+SS
Sbjct: 501 DGSDGQVVYSI-IQGSGLGVFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSS 559

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
            + V +KI+D++D  P F          E SP  T +  ++  D D G +  V YSI G 
Sbjct: 560 NLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITG- 616

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
             ++SF +    G     ++T   +D  +    YELV+ A S
Sbjct: 617 --ASSFKIVPTSGL----ILTTGPIDLTTEPSTYELVVTATS 652



 Score =  155 bits (375), Expect = 6e-37
 Identities = 148/515 (28%), Positives = 235/515 (45%), Gaps = 50/515 (9%)

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK--Q 433
           E+EP G  V +  +  ++E       + T   +  R    S++G  ++    PL +   +
Sbjct: 37  ENEPEGFRVFSFPSPPSNEIYSFFRALDTASQSALRLFDISEDG--VVVTKNPLVYTDGE 94

Query: 434 ERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
           E  YVLTV     G         ++I +TD NN+ P F    Y   + E+A  GTTV  +
Sbjct: 95  ENLYVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGL 154

Query: 492 SATDSDVGINAQIT-YSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGY 547
               ++    + I  Y + S   NE      +   +  Q   +   T  +++        
Sbjct: 155 EKCHAEDKDRSGIDRYEIVS--GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSI 212

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            LTV A DGG   L  TT ++I + D N+N PVF++  YT  + ED  V TS+ +V A D
Sbjct: 213 TLTVRANDGG--GLHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARD 270

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           AD+G NG I+Y L    R    F ID  +GVIR  + LD +S     L+  A D G+ P+
Sbjct: 271 ADIGRNGGIYYYL----RNTQDFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPK 326

Query: 668 SSTVIVHIKIE-DIN--------------DSPPVF-ESDCLTFYISENSPIGTTIGEIRA 711
           ++ V V + I  DI+              + PPVF E    T  I E+ P+   I  ++A
Sbjct: 327 AANVNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKA 386

Query: 712 HDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           +DPD G  N  + YS+ G   +N+F++++  G     L T ++      +   +LV+ A 
Sbjct: 387 NDPDAGSTNGQLRYSLSG---NNNFAIDSTSG--VVTLQTQLEYKGNPAQDVIDLVVTAT 441

Query: 771 -----SPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822
                S  L   V  ++E+L  D N+NAPV    Q+     +D        RV A D+D 
Sbjct: 442 DRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDD 501

Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
               ++ Y I+ G+   +  +  TTG + ++  L+
Sbjct: 502 GSDGQVVYSIIQGSGLGVFQVQATTGDLIVAAPLD 536



 Score =  151 bits (367), Expect = 6e-36
 Identities = 165/574 (28%), Positives = 253/574 (44%), Gaps = 72/574 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-KATDQDIGKNAEVEYTIELVTAD 68
           +I V D N+  P F    Y   + E A+ GTTV  L K   +D  ++    Y  E+V+ +
Sbjct: 119 RITVTDTNNFQPTFGADLYLGYIAEEAAQGTTVGGLEKCHAEDKDRSGIDRY--EIVSGN 176

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
               E             Q    +   +    TR   D  + +  T+ V+A D       
Sbjct: 177 ----ERGYFVAETKTVGAQKFLVLKATN----TRIVRDPARPS-ITLTVRANDGGG---- 223

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            L  T  I ++I D N+N P F +  YTV+V ED  V  +  I +++A DAD+G N  I 
Sbjct: 224 -LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTS--ILRVRARDADIGRNGGIY 280

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y +   NTQ  F+ID+++G +  ++ LD++  +   L + A+D GS  ++    + + IR
Sbjct: 281 YYL--RNTQ-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIR 337

Query: 249 -DVND-------------NAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEG-VNAE 291
            D++              N P  +   S F  S+ E+ P+  +I  V+A D D G  N +
Sbjct: 338 SDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQ 397

Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD---RETQAKYQLLVTATD----GGDP 344
           L Y++     +GN +    ID  SG V    QL+      Q    L+VTATD     G  
Sbjct: 398 LRYSL-----SGNNN--FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGAL 450

Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402
             S                  F P Q E+ ++ED   G  +  ++ATD+D+  D ++ Y 
Sbjct: 451 SASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYS 510

Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINIT 460
           I  G+  G F + +  G   + VA PLD ++   Y L + A D     +S    V + I 
Sbjct: 511 IIQGSGLGVFQVQATTGD--LIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQ 568

Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
           D +++ P F    Y A   E +P  T V VV   D D+G    ++YS++   S       
Sbjct: 569 DVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGASS------- 619

Query: 521 DQQFVINPQTGAITTNKLLDRET-MSGYLLTVTA 553
              F I P +G I T   +D  T  S Y L VTA
Sbjct: 620 ---FKIVPTSGLILTTGPIDLTTEPSTYELVVTA 650



 Score =  147 bits (356), Expect = 1e-34
 Identities = 131/461 (28%), Positives = 208/461 (45%), Gaps = 35/461 (7%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           QI++ D N++ PVFE  +Y  +V E     T++L ++A D DIG+N  + Y +       
Sbjct: 231 QIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYYYLR------ 284

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N +D           ++ +  +D +SG   T     R++            Q +  SD 
Sbjct: 285 -NTQD--FTIDAITGVIRPIRMLDFQSGQQRTLEVTARDR-GSSPKAANVNVQVTIRSDI 340

Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAI 187
                 +  +   D +  P F E  ++T+S+ ED  V  N  I  +KA D D G+ N  +
Sbjct: 341 SGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPV--NGAIQVVKANDPDAGSTNGQL 398

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQD--GGSPSRSNTTQ 242
           RY++ G N    F+IDS SG V+L   L+Y+   +     LV+ A D  G S + S +  
Sbjct: 399 RYSLSGNN---NFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVN 455

Query: 243 LLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           L I + DV  N+NAP F     + +VSE+  +G +I RV A D+D+G + ++ Y++    
Sbjct: 456 LKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSIIQGS 515

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             G   +  T    +G +  +  LDRE  + Y L++ A D    P+S+            
Sbjct: 516 GLGVFQVQAT----TGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVD 571

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                F    Y  +  E  P  T V  +   D D    + Y ITG ++   F I   +  
Sbjct: 572 DHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGASS---FKIVPTS-- 626

Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSG-GRSDTAMVQINI 459
           GLI    P+D   E   Y L V+AT +  G +  A  Q+N+
Sbjct: 627 GLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNV 667



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 15/55 (27%), Positives = 25/55 (45%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
           ++  + + D +DH P F    Y A   E +   T V  +K  D D+G++     T
Sbjct: 561 LYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSIT 615


>SB_51258| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 484

 Score =  153 bits (371), Expect = 2e-36
 Identities = 114/342 (33%), Positives = 165/342 (48%), Gaps = 30/342 (8%)

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKY---QLLVTATDGGDPPRSATATXXXXXXXXXX 361
           V + +T  PR+   Y    L+ E   +    +++V  TDGG P   + A           
Sbjct: 151 VVIDVTPKPRN-LTYDVSVLEGEANVQVMDLKVVVNVTDGGSPALKSRAMVVIDVTPKPR 209

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQN 418
                    Y+V + E E     V+ L   ++      H+  +GG         S+ S N
Sbjct: 210 NLT------YDVSVLEGEA-NVQVMDLKPAES------HFNASGGTFAFFGSSGSMFSIN 256

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
           G  L   + PLD +    +VL +S T+ G       V +N+ D N+  P F++  +  SV
Sbjct: 257 GTNLRVGSTPLDRETAEEHVLDISLTEGGIVKGLFKVTVNVLDINDETPSFQSPSFNVSV 316

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            E   +GT  L VSATDSD G N+ +TYS+       A  + +  F IN +T AI+  K 
Sbjct: 317 NEIERLGTVFLTVSATDSDAGANSALTYSI-------AAGNEEGFFSINNKTSAISVAKQ 369

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRET   Y+LTV A+DGG PSL+ T  V I V D NDN PV +  +   ++ E A + T
Sbjct: 370 LDRETRDLYMLTVMAQDGGEPSLNRTAAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDT 429

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVI 639
            V+ V A+D D+G NGR+ Y ++      G F I D +SG I
Sbjct: 430 PVATVIASDKDIGANGRLLYSIE--SGAHGHFQIKDSSSGAI 469



 Score =  124 bits (299), Expect = 1e-27
 Identities = 124/450 (27%), Positives = 188/450 (41%), Gaps = 37/450 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ PV +      S+ E A+  T V T+ A+D+DIG N  + Y+IE       
Sbjct: 48  IQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHF 107

Query: 71  NPEDAXXXXXXXXXXVQDVFR---------IDGRSGALLTRASLDREKVARYTVLVKATD 121
             +D+          +    R          DG S AL +RA +  +   +   L     
Sbjct: 108 QIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVS 167

Query: 122 QASPVSDRLSSTATIHVNIIDDN------------DNYPQFSEKTYTVSVDEDISVTDNP 169
                ++       + VN+ D              D  P+    TY VSV E  +   N 
Sbjct: 168 VLEGEANVQVMDLKVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVSVLEGEA---NV 224

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
            +  +K  ++   A+    +A  G +  M FSI+  +  V     LD E    + L I  
Sbjct: 225 QVMDLKPAESHFNASGG-TFAFFGSSGSM-FSINGTNLRVGST-PLDRETAEEHVLDISL 281

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
            +GG        ++ +N+ D+ND  P F +  F  SV+E   +G   + V A D+D G N
Sbjct: 282 TEGGIV--KGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGTVFLTVSATDSDAGAN 339

Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
           + LTY++      GN +   +I+ ++  +  + QLDRET+  Y L V A DGG+P  + T
Sbjct: 340 SALTYSIA----AGNEEGFFSINNKTSAISVAKQLDRETRDLYMLTVMAQDGGEPSLNRT 395

Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407
           A                     +V L+E     TPV T+ A+D D   + RL Y I  G 
Sbjct: 396 AAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLLYSIESG- 454

Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRY 437
             G F I   +  G I+VA  L + Q   Y
Sbjct: 455 AHGHFQI-KDSSSGAISVADRLSYNQRNNY 483



 Score =  117 bits (282), Expect = 1e-25
 Identities = 65/191 (34%), Positives = 101/191 (52%), Gaps = 3/191 (1%)

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRET   ++L ++  +GG+  +     V ++V+D+ND  P F+   +  ++ E   +GT
Sbjct: 267 LDRETAEEHVLDISLTEGGI--VKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGT 324

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
               V ATD+D G N  + Y +     EEG F I+  +  I   K LDRE+   + L  +
Sbjct: 325 VFLTVSATDSDAGANSALTYSI-AAGNEEGFFSINNKTSAISVAKQLDRETRDLYMLTVM 383

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           A DGG P  + T  V I++ D ND+PPV +   +   +SE + I T +  + A D D G 
Sbjct: 384 AQDGGEPSLNRTAAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGA 443

Query: 719 NAVVHYSIKGG 729
           N  + YSI+ G
Sbjct: 444 NGRLLYSIESG 454



 Score =  104 bits (250), Expect = 9e-22
 Identities = 62/155 (40%), Positives = 83/155 (53%), Gaps = 3/155 (1%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ TT V I V D NDN PV + 
Sbjct: 3   FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 62

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTN 642
            +   ++ E A + T V+ V A+D D+G NGR+ Y ++      G F I D +SG I   
Sbjct: 63  AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLA 120

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
             L       + +     DGG+P   S  +V I +
Sbjct: 121 GMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 155



 Score = 94.3 bits (224), Expect = 1e-18
 Identities = 57/159 (35%), Positives = 86/159 (54%), Gaps = 7/159 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F I+ ++GA+     LDRE   +YT+ V A D   P    L+ST  + + + D NDN P 
Sbjct: 3   FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---LNSTTAVAIQVGDANDNPPV 59

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGD 208
             +    VS+ E  ++ D PV A + A+D D+GAN  + Y+I  G     F I DS SG 
Sbjct: 60  IQDAVIRVSLSETAAI-DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGA 116

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +SL   L Y Q  +Y +V+   DGGSP+  +   ++I++
Sbjct: 117 ISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 155



 Score = 88.6 bits (210), Expect = 6e-17
 Identities = 51/151 (33%), Positives = 77/151 (50%), Gaps = 4/151 (2%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           FSI++ +G +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    
Sbjct: 3   FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 62

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           ++ + S+SE   I   +  V A D D G N  L Y++ +    G+  +    D  SG + 
Sbjct: 63  AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFQIK---DSSSGAIS 118

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
            +G L    +  Y ++V  TDGG P   + A
Sbjct: 119 LAGMLSYNQRNNYIVVVNVTDGGSPALKSRA 149



 Score = 83.4 bits (197), Expect = 2e-15
 Identities = 58/162 (35%), Positives = 83/162 (51%), Gaps = 11/162 (6%)

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVF 469
           FSI   N  G I+VA+ LD +   +Y LTV A D G    + T  V I + DAN+  PV 
Sbjct: 3   FSIN--NKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVI 60

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
           ++A    S+ E A I T V  V A+D D+G N ++ YS+      E+ AH   Q + +  
Sbjct: 61  QDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSS 113

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
           +GAI+   +L     + Y++ V   DGG P+L     V I V
Sbjct: 114 SGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 155



 Score = 82.6 bits (195), Expect = 4e-15
 Identities = 64/219 (29%), Positives = 102/219 (46%), Gaps = 12/219 (5%)

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           LDRE+   H L     +GG       V V++   DIND  P F+S      ++E   +GT
Sbjct: 267 LDRETAEEHVLDISLTEGGIVKGLFKVTVNVL--DINDETPSFQSPSFNVSVNEIERLGT 324

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
               + A D D G N+ + YSI  G++   FS+  +  +    +     LD E+ R  Y 
Sbjct: 325 VFLTVSATDSDAGANSALTYSIAAGNEEGFFSINNKTSA----ISVAKQLDRET-RDLYM 379

Query: 765 LVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821
           L + A     P L     V I V D NDN PV++D  I  +  +      P   V A D 
Sbjct: 380 LTVMAQDGGEPSLNRTAAVAIQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDK 439

Query: 822 DV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858
           D+    +L Y I SG + +  + + ++G+++++ +L+ N
Sbjct: 440 DIGANGRLLYSIESGAHGHFQIKDSSSGAISVADRLSYN 478



 Score = 82.2 bits (194), Expect = 5e-15
 Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 15/193 (7%)

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
           +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T                    
Sbjct: 4   SINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDA 63

Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
              V L+E     TPV T+ A+D D   + RL Y I  G   G F I   +  G I++A 
Sbjct: 64  VIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQI-KDSSSGAISLAG 121

Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE---DA 482
            L + Q   Y++ V+ TD G  +    AMV I++T      P   N  Y  SV E   + 
Sbjct: 122 MLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PKPRNLTYDVSVLEGEANV 175

Query: 483 PIGTTVLVVSATD 495
            +    +VV+ TD
Sbjct: 176 QVMDLKVVVNVTD 188



 Score = 76.2 bits (179), Expect = 4e-13
 Identities = 55/159 (34%), Positives = 79/159 (49%), Gaps = 8/159 (5%)

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
           F I+  +G I   K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV + 
Sbjct: 3   FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 62

Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
             +   +SE + I T +  + A D D G N  + YSI+ G   + F ++    S    L 
Sbjct: 63  AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAISLA 120

Query: 750 TMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVT 785
            M  L Y + R  Y +V+      SP L +   V I VT
Sbjct: 121 GM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 156



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 6/124 (4%)

Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
           LD E+ R +Y L + A     PPL +   V I V D NDN PV++D  I  +  +     
Sbjct: 18  LDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAID 76

Query: 811 GPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
            P   V A D D+    +L Y I SG + +  + + ++G+++L+  L+ N      + V+
Sbjct: 77  TPVATVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVN 136

Query: 869 VTDG 872
           VTDG
Sbjct: 137 VTDG 140


>SB_24627| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 262

 Score =  145 bits (352), Expect = 4e-34
 Identities = 87/224 (38%), Positives = 120/224 (53%), Gaps = 10/224 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V IN+ D N+  P+F++  +  SV E   +GT  L VSATD D G N+ +TYS+      
Sbjct: 22  VTINVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI------ 75

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
            A  + +  F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ TT V I V D 
Sbjct: 76  -AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDA 134

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-D 633
           NDN PV +  +   ++ E A + T V+ V A+D D+G NGR+ Y ++      G F I D
Sbjct: 135 NDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKD 192

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            +SG I     L       + +     DGG+P   S  +V I +
Sbjct: 193 SSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 236



 Score =  135 bits (327), Expect = 4e-31
 Identities = 80/226 (35%), Positives = 119/226 (52%), Gaps = 7/226 (3%)

Query: 126 VSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
           +S+ LS  A  + +N++D ND  P F   ++ VSV+E   +    V   + ATD D GAN
Sbjct: 11  ISEDLSYIALQVTINVLDINDETPLFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGAN 68

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           SA+ Y+I  GN +  FSI++ +G +S+ K LD E    Y L + AQDGG P  ++TT + 
Sbjct: 69  SALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVA 128

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I + D NDN P    ++ Q S+SE   I   +  V A D D G N  L Y++ +    G+
Sbjct: 129 IQVGDANDNPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSI-ESGAHGH 187

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
             +    D  SG +  +G L    +  Y ++V  TDGG P   + A
Sbjct: 188 FQIK---DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRA 230



 Score =  121 bits (292), Expect = 7e-27
 Identities = 81/238 (34%), Positives = 119/238 (50%), Gaps = 26/238 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           INVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I        
Sbjct: 24  INVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 75

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +  F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 76  -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 121

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +ST  + + + D NDN P   +    VS+ E  ++ D PV A + A+D D+GAN  + Y+
Sbjct: 122 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAAI-DTPV-ATVIASDKDIGANGRLMYS 179

Query: 191 IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           I  G     F I DS SG +SL   L Y Q  +Y +V+   DGGSP+  +   ++I++
Sbjct: 180 IESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDV 236



 Score =  116 bits (278), Expect = 4e-25
 Identities = 77/222 (34%), Positives = 112/222 (50%), Gaps = 9/222 (4%)

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
           V I+V+D+ND  P+F+   +  ++ E   +GT    V ATD D G N  + Y +     E
Sbjct: 22  VTINVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNE 80

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
           EG F I+  +G I   K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV
Sbjct: 81  EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPV 140

Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
            +   +   +SE + I T +  + A D D G N  + YSI+ G   + F ++    S   
Sbjct: 141 IQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAI 198

Query: 747 ELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVT 785
            L  M  L Y + R  Y +V+      SP L +   V I VT
Sbjct: 199 SLAGM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 237



 Score =  108 bits (259), Expect = 7e-23
 Identities = 75/210 (35%), Positives = 107/210 (50%), Gaps = 13/210 (6%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F    + V + E E  GT  +T++ATD D   ++ L Y I  GN  G FSI   N  G I
Sbjct: 36  FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSIN--NKTGAI 93

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481
           +VA+ LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    S+ E 
Sbjct: 94  SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSET 153

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A I T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+   +L  
Sbjct: 154 AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSY 206

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
              + Y++ V   DGG P+L     V I V
Sbjct: 207 NQRNNYIVVVNVTDGGSPALKSRAMVVIDV 236



 Score = 92.3 bits (219), Expect = 5e-18
 Identities = 64/205 (31%), Positives = 102/205 (49%), Gaps = 10/205 (4%)

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           V I + DIND  P+F+S      ++E   +GT    + A D D G N+ + YSI  G++ 
Sbjct: 22  VTINVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEE 81

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789
             FS+  + G+    +     LD E+ R +Y L + A     PPL +   V I V D ND
Sbjct: 82  GFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAND 136

Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTG 847
           N PV++D  I  +  +      P   V A D D+    +L Y I SG + +  + + ++G
Sbjct: 137 NPPVIQDAVIQVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSG 196

Query: 848 SMTLSPQLNTNVPKLATMEVSVTDG 872
           +++L+  L+ N      + V+VTDG
Sbjct: 197 AISLAGMLSYNQRNNYIVVVNVTDG 221



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 778 VRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833
           ++V I V D+ND  P+ +   F +  N  +    V  F  V A D D      L Y I +
Sbjct: 20  LQVTINVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAA 77

Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           GN      +N  TG+++++ QL+       T+ V   DG
Sbjct: 78  GNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 116


>SB_14427| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 2325

 Score =  144 bits (350), Expect = 7e-34
 Identities = 193/736 (26%), Positives = 306/736 (41%), Gaps = 83/736 (11%)

Query: 95   RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
            R+GALL    LD E  A++TV ++A D  +P       T +  V ++DDND  P  +   
Sbjct: 308  RNGALLATRPLDFESHAQWTVRIRAQDSGTPSK---YFTESFTVRVLDDND--PPTAITL 362

Query: 155  YTVSVDEDISVTDNPVIAKIKATDADVGANSAI--------RYAIIGGNTQMQFSIDSLS 206
             + +VDE+  +  + ++  +   D D G             R+ I G   ++  S     
Sbjct: 363  SSSAVDENSGI--DTLVGYLSTRDEDSGQRFTYTLLDSARGRFKIEGDKLKVAQSNRECL 420

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
                    L+YE  +++ + +R  D G+   +    L I IRD+ND  PR    L    V
Sbjct: 421  RQGGNSCLLNYEHNQTHLIRVRTTDSGTIPLTYDAVLTITIRDINDQ-PRDL-QLSNNRV 478

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
            +EN  IG S     + D D G +  L Y+++D D  G       +D   G ++ +  +D 
Sbjct: 479  AENASIGSSFGTFSSRDEDAGQS--LVYSLSDDD--GG---RFRVDA-VGKLFKAKDMDY 530

Query: 327  ETQAKYQLLVTATDGGDPP----RSATATXXXXXXXXXXXXXXFMPGQYEV-----ELAE 377
            ETQ  + +    TD G P     +  T                   GQ        ++ E
Sbjct: 531  ETQRSHVIQAVVTDNGSPAMKMEKQFTIEVLDINEAPVHLNFTSTDGQLAFPPNSPKVRE 590

Query: 378  DEPPGTPVVTLTATDADEDNRL--HYEITGG-----NTRGRFSITSQNGRGLIT------ 424
            +   GT V TL A D D   +L  H + + G     +      +   N RG  T      
Sbjct: 591  NSELGTVVGTLEALDYDALQQLSFHLDDSAGEAFSLSASASLCVPVTNMRGFNTRCTHTL 650

Query: 425  -VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV---FENAPYTASVFE 480
             V   L+++Q + + +    TD+ G   T   ++ ITD N+ AP          TA+V E
Sbjct: 651  RVNTTLNYEQNQAHYIVARVTDNKGLFTTRRFRVTITDEND-APAGITLAGNSLTATVDE 709

Query: 481  DAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            +A  G  V  +   D D   +AQ  TY L+ + +   V   ++ +V        + +  L
Sbjct: 710  NAN-GALVGELVTIDED---SAQSHTYVLTDDAAGRFVTRANKLYV--------SRSANL 757

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D E+ + Y +T+ + D G PSL+ +    I V DVN  E   K  L  + + E++   T 
Sbjct: 758  DYESKNTYNITIRSTDTGNPSLNVSNTFSILVRDVN--EAPSKVSLSNSRVQENSPKDTV 815

Query: 600  VSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            + Q+  TD D    N R  ++    D   G FV+D  + +      LD E      +   
Sbjct: 816  IGQLTVTDPDNSAYNSRQSHKCSVVDDMIGQFVVDQGNVLKVGRVVLDFEQATVISVPVK 875

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
             +D G PP S  V+ +I ++D+N+SP        +  I+EN P  T IG +   DPD   
Sbjct: 876  CVDSGYPPLSLQVVFNITVDDVNESPADIALSGNS--IAENVP-ATYIGTLTTTDPDNEA 932

Query: 719  --NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPP 773
                   Y++ G      F +      D A L +   L+YE  +  +   IR   + +PP
Sbjct: 933  QFRQTFTYTLMGDTAGIPFVI------DGAALNSTRPLNYER-KAFWVFTIRSTDSGTPP 985

Query: 774  LWNDVRVEILVTDVND 789
            L       I V DVN+
Sbjct: 986  LSVTKTFNITVVDVNE 1001



 Score =  130 bits (313), Expect = 2e-29
 Identities = 159/613 (25%), Positives = 265/613 (43%), Gaps = 70/613 (11%)

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL---FQE 264
           DV++   LD+E  +S  +++RA D  S    ++    + + DVND  P    +L      
Sbjct: 7   DVTVGVRLDFEVSQSELIIVRATD--SSGLFHSVAFNVTVIDVND--PPINVTLDGSLSG 62

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ- 323
           +V+EN    + I  +Q   ADE ++   +Y +   D  GN ++      R+  +YTS   
Sbjct: 63  TVNENSR-DFLIGSLQT--ADEDLHQTYSYILLS-DGGGNFEI------RADKLYTSSSA 112

Query: 324 -LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            LD E    YQL V +TD G PP S   T                     +   E+ PPG
Sbjct: 113 NLDFEVARSYQLRVRSTDSGTPPLSVEGTVTITISDVNERPTNISLSASTI--TENTPPG 170

Query: 383 TPVVTLTATDADE-----DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
           T +  L+  D D      D + H      ++ GR +I    G  L+  +  +++++    
Sbjct: 171 TVIGRLSVIDPDNLGPQGDRQRHVCRLTDSSNGRVAI---QGNQLVVGSAGVNYERGSSL 227

Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            +TVS  D GG    A   ++++D N        +  +  + E+ P  T V  +  TD D
Sbjct: 228 NVTVSCADPGGLELLASFTVDVSDVNESPTAISIS--SLQILENRPALTKVGDLKVTDPD 285

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
             +  + T++L+       V      F +  + GA+   + LD E+ + + + + A+D G
Sbjct: 286 NEVCQRQTFNLT-------VLSPLSPFKV--RNGALLATRPLDFESHAQWTVRIRAQDSG 336

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
            PS   T    + V+D  DN+P     L ++ + E++ + T V  +   D D G   R  
Sbjct: 337 TPSKYFTESFTVRVLD--DNDPPTAITLSSSAVDENSGIDTLVGYLSTRDEDSG--QRFT 392

Query: 618 YELDPKDREEGSFVID-PASGVIRTNK----------ALDRESVATHDLKAVAIDGGTPP 666
           Y L   D   G F I+     V ++N+           L+ E   TH ++    D GT P
Sbjct: 393 YTL--LDSARGRFKIEGDKLKVAQSNRECLRQGGNSCLLNYEHNQTHLIRVRTTDSGTIP 450

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            +   ++ I I DIND P   +       ++EN+ IG++ G   + D D G + V  YS+
Sbjct: 451 LTYDAVLTITIRDINDQPR--DLQLSNNRVAENASIGSSFGTFSSRDEDAGQSLV--YSL 506

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK--YELVIRAASPPLWNDVRVEILV 784
              DD   F ++        +L    D+DYE+ R      +V    SP +  + +  I V
Sbjct: 507 -SDDDGGRFRVDA-----VGKLFKAKDMDYETQRSHVIQAVVTDNGSPAMKMEKQFTIEV 560

Query: 785 TDVNDNAPVMKDF 797
            D+N+ APV  +F
Sbjct: 561 LDINE-APVHLNF 572



 Score =  128 bits (308), Expect = 8e-29
 Identities = 185/721 (25%), Positives = 297/721 (41%), Gaps = 79/721 (10%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           LD E      ++V+ATD     S  L  +   +V +ID ND  P  +     V++D  +S
Sbjct: 14  LDFEVSQSELIIVRATD-----SSGLFHSVAFNVTVIDVND--PPIN-----VTLDGSLS 61

Query: 165 VTDNP-----VIAKIKATDADVGAN-SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
            T N      +I  ++  D D+    S I  +  GGN +++   D L    S    LD+E
Sbjct: 62  GTVNENSRDFLIGSLQTADEDLHQTYSYILLSDGGGNFEIR--ADKLYTSSSA--NLDFE 117

Query: 219 QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278
             RSY+L +R+ D G+P  S    + I I DVN+       SL   +++EN P G  I R
Sbjct: 118 VARSYQLRVRSTDSGTPPLSVEGTVTITISDVNERPTNI--SLSASTITENTPPGTVIGR 175

Query: 279 VQAYDAD----EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
           +   D D    +G        +TD    G V +       +  V  S  ++ E  +   +
Sbjct: 176 LSVIDPDNLGPQGDRQRHVCRLTDSS-NGRVAIQ-----GNQLVVGSAGVNYERGSSLNV 229

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
            V+  D G     A+ T                     +++ E+ P  T V  L  TD D
Sbjct: 230 TVSCADPGGLELLASFTVDVSDVNESPTAISIS----SLQILENRPALTKVGDLKVTDPD 285

Query: 395 ED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD- 451
            +   R  + +T  +    F +  +NG  L T  +PLDF+   ++ + + A DSG  S  
Sbjct: 286 NEVCQRQTFNLTVLSPLSPFKV--RNGALLAT--RPLDFESHAQWTVRIRAQDSGTPSKY 341

Query: 452 -TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            T    + + D N+  P       +++V E++ I T V  +S  D D G   + TY+L  
Sbjct: 342 FTESFTVRVLDDND--PPTAITLSSSAVDENSGIDTLVGYLSTRDEDSG--QRFTYTLLD 397

Query: 511 EISNEAVAHHDQQFVINPQTGAIT---TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
                     D+  V       +     + LL+ E    +L+ V   D G   L+    +
Sbjct: 398 SARGRFKIEGDKLKVAQSNRECLRQGGNSCLLNYEHNQTHLIRVRTTDSGTIPLTYDAVL 457

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            I++ D+ND       QL    + E+A +G+S     + D D G +  + Y L   D + 
Sbjct: 458 TITIRDINDQPRDL--QLSNNRVAENASIGSSFGTFSSRDEDAGQS--LVYSLS--DDDG 511

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-- 685
           G F +D A G +   K +D E+  +H ++AV  D G+P         I++ DIN++P   
Sbjct: 512 GRFRVD-AVGKLFKAKDMDYETQRSHVIQAVVTDNGSPAMKMEKQFTIEVLDINEAPVHL 570

Query: 686 --VFESDCLTF-----YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD---SNSF 735
                   L F      + ENS +GT +G + A D D       H     G+    S S 
Sbjct: 571 NFTSTDGQLAFPPNSPKVRENSELGTVVGTLEALDYDALQQLSFHLDDSAGEAFSLSASA 630

Query: 736 SL----ETRQGSDKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
           SL       +G +     T+     L+YE  +  Y +     +  L+   R  + +TD N
Sbjct: 631 SLCVPVTNMRGFNTRCTHTLRVNTTLNYEQNQAHYIVARVTDNKGLFTTRRFRVTITDEN 690

Query: 789 D 789
           D
Sbjct: 691 D 691



 Score =  119 bits (287), Expect = 3e-26
 Identities = 168/706 (23%), Positives = 292/706 (41%), Gaps = 62/706 (8%)

Query: 32   VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91
            VRE +  GT V TL+A D D  +  ++ + ++    D+     +          V ++  
Sbjct: 588  VRENSELGTVVGTLEALDYDALQ--QLSFHLD----DSAGEAFSLSASASLCVPVTNMRG 641

Query: 92   IDGR-SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP-- 148
             + R +  L    +L+ E+   + ++ + TD        L +T    V I D+ND     
Sbjct: 642  FNTRCTHTLRVNTTLNYEQNQAHYIVARVTDNKG-----LFTTRRFRVTITDENDAPAGI 696

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
              +  + T +VDE+    +  ++ ++   D D   +      ++  +   +F   +    
Sbjct: 697  TLAGNSLTATVDEN---ANGALVGELVTIDEDSAQSHTY---VLTDDAAGRFVTRANKLY 750

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            VS    LDYE   +Y + IR+ D G+PS + +    I +RDVN+ AP    SL    V E
Sbjct: 751  VSRSANLDYESKNTYNITIRSTDTGNPSLNVSNTFSILVRDVNE-APS-KVSLSNSRVQE 808

Query: 269  NVPIGYSIVRVQAYDADEGV-NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LD 325
            N P    I ++   D D    N+  ++  +  D   ++     +D   G V   G+  LD
Sbjct: 809  NSPKDTVIGQLTVTDPDNSAYNSRQSHKCSVVD---DMIGQFVVD--QGNVLKVGRVVLD 863

Query: 326  RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTP 384
             E      + V   D G PP S                    + G     +AE+  P T 
Sbjct: 864  FEQATVISVPVKCVDSGYPPLSLQVVFNITVDDVNESPADIALSGN---SIAEN-VPATY 919

Query: 385  VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
            + TLT TD D + +     T         I        +   +PL+++++  +V T+ +T
Sbjct: 920  IGTLTTTDPDNEAQFRQTFTYTLMGDTAGIPFVIDGAALNSTRPLNYERKAFWVFTIRST 979

Query: 445  DSGGRSDTAMVQINITDAN-NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            DSG    +     NIT  + N AP +     ++ V E++   T +  +S  D D   +  
Sbjct: 980  DSGTPPLSVTKTFNITVVDVNEAP-YGITVSSSDVDENSGQDTVIGTLSCQDPD--FDQS 1036

Query: 504  ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK---LLDRETMSGYLLTVTARDGGVPS 560
             +Y+L  +        +D   V    +  I        L+ E    +++ V + D G P+
Sbjct: 1037 HSYTLIDDAGGRFKVENDTLMVALSNSDCIRLGGSACKLNYEGQRQHVIRVRSTDNGAPA 1096

Query: 561  LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
             +    + I+V DVND     +   +   + E+A +GT + ++ A+D D      + + L
Sbjct: 1097 RTSEKSLVITVNDVNDRPRDLRMSGF--KVEENAPIGTRIGKLTASDED--KYQTLSFSL 1152

Query: 621  DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
               D ++G F ID +SG +   KA D E+   H + A A D GT   +      I + +I
Sbjct: 1153 --VDDDKGRFAID-SSGYVMKVKATDYETSQLHTIIAQARDNGTKTLAVNQTFTIVVVNI 1209

Query: 681  NDSP-----------PVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
            N++P             F  +  T  +SENSP GT +G + + D D
Sbjct: 1210 NEAPINISITSLNGQQAFPDNAPT--VSENSPNGTVVGTLFSLDHD 1253



 Score =  113 bits (271), Expect = 3e-24
 Identities = 124/508 (24%), Positives = 206/508 (40%), Gaps = 38/508 (7%)

Query: 200  FSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
            F+I+S SG +SL    LDYEQ  +Y L +R+ D G P  S   Q  +N+ DV DN  R  
Sbjct: 1685 FAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDNGLPPLSTLGQFFVNVIDVLDNNDRPQ 1744

Query: 259  -TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
               L   +V EN   G  I  +QA D D   N   ++++ D+      DL    + R   
Sbjct: 1745 GIQLSPSTVLENATAGAVIGSLQARDQD--ANQTHSFSVVDR-----TDL---FEVRGSK 1794

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            +     ++ E      + + A D G P  S                   +     + L E
Sbjct: 1795 LVLVSSVNYEENPTINVTIRAADDGSPSLSKEEVLAVTVIDCNDAPSDVIIRPQNIVLPE 1854

Query: 378  DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
            +   GTP+  +T  D D     +  +  G         S++  G+   A  LDF+  ++ 
Sbjct: 1855 NSKSGTPLANVTVVDDDTLQEHYCTLIDGQRYFYIKKLSRSEAGIFVAASELDFETMKQP 1914

Query: 438  V-LTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            + +TV  TD G    +     N+T ++ N AP       +  V E+   G  +  +S  D
Sbjct: 1915 ITVTVKCTDDGNPQYSNQRSFNVTLSDINEAPYDITLTGSPVVEENVVKGYAIGSLSCKD 1974

Query: 496  SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM---SGYLLTVT 552
             DVG          S +  + V  +D  F +N     +     LD E +   +   +++ 
Sbjct: 1975 PDVG---------QSHVF-QVVGKYDNVFEVNGTNLIVKDPSYLDHEALPPPATLHISIR 2024

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A D G   L  T DV I+V DVN+     +       + ED   G  ++QV +T+ +V  
Sbjct: 2025 ATDNGDTPLDVTNDVTINVTDVNEAPYDIRLVPSHVTVKEDIRTGQCIAQVTSTNPEVEQ 2084

Query: 613  N---GRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGG 663
                  + Y+ + +       S +    +  +  N  L  + +     T+D+   A+D G
Sbjct: 2085 TVSYSLLSYQTEFRINAVCLNSSLSSGNAAYLTVNGPLSYDKMESLNYTYDIMVEAMDNG 2144

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDC 691
             PP +    V +++E ++  P V E+ C
Sbjct: 2145 IPPLAWNDSVFVRVERVD--PCVNETVC 2170



 Score =  103 bits (246), Expect = 3e-21
 Identities = 160/610 (26%), Positives = 253/610 (41%), Gaps = 60/610 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND +P         ++ E + SGT + TL   DQD+ ++    Y IE VTA   
Sbjct: 1616 ITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITADQDVRQSHS--YNIEHVTAYGF 1672

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSDR 129
              +            +  +F I+  SG L L+   LD E+ A YT+ V++TD   P    
Sbjct: 1673 GGKS-------NSSSLLGLFAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDNGLP---P 1722

Query: 130  LSSTATIHVNIID--DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            LS+     VN+ID  DN++ PQ  + + +  ++   + T   VI  ++A D D  AN   
Sbjct: 1723 LSTLGQFFVNVIDVLDNNDRPQGIQLSPSTVLE---NATAGAVIGSLQARDQD--ANQTH 1777

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             ++++   T +    +     + LV +++YE+  +  + IRA D GSPS S    L + +
Sbjct: 1778 SFSVV-DRTDL---FEVRGSKLVLVSSVNYEENPTINVTIRAADDGSPSLSKEEVLAVTV 1833

Query: 248  RDVNDNAPRFYTSLFQESV-SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
             D ND AP       Q  V  EN   G  +  V   D D+ +       +  + Y     
Sbjct: 1834 IDCND-APSDVIIRPQNIVLPENSKSGTPLANVTVVD-DDTLQEHYCTLIDGQRYFYIKK 1891

Query: 307  LPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            L  +    +G    + +LD ET  +   + V  TD G+P  S   +              
Sbjct: 1892 LSRS---EAGIFVAASELDFETMKQPITVTVKCTDDGNPQYSNQRSFNVTLSDINEAPYD 1948

Query: 366  F-MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
              + G   VE  E+   G  + +L+  D D      +++ G       ++   NG  LI 
Sbjct: 1949 ITLTGSPVVE--ENVVKGYAIGSLSCKDPDVGQSHVFQVVGKYD----NVFEVNGTNLI- 2001

Query: 425  VAQP--LDFK---QERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTAS 477
            V  P  LD +         +++ ATD+G      T  V IN+TD N         P   +
Sbjct: 2002 VKDPSYLDHEALPPPATLHISIRATDNGDTPLDVTNDVTINVTDVNEAPYDIRLVPSHVT 2061

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSS---EISNEAVAHHDQQFVINPQTGAIT 534
            V ED   G  +  V++T+ +V     ++YSL S   E    AV  +    + +     +T
Sbjct: 2062 VKEDIRTGQCIAQVTSTNPEV--EQTVSYSLLSYQTEFRINAVCLNSS--LSSGNAAYLT 2117

Query: 535  TNKLLDRETMSG----YLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTA 588
             N  L  + M      Y + V A D G+P L  +D+  V +  VD   NE V       A
Sbjct: 2118 VNGPLSYDKMESLNYTYDIMVEAMDNGIPPLAWNDSVFVRVERVDPCVNETVCDGNATCA 2177

Query: 589  NIMEDALVGT 598
             +   +L  T
Sbjct: 2178 RVKGTSLTCT 2187



 Score =  102 bits (245), Expect = 4e-21
 Identities = 138/542 (25%), Positives = 229/542 (42%), Gaps = 48/542 (8%)

Query: 214  TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273
            TL+YEQ +++ +V R  D  +     T +  + I D ND AP   T L   S++  V   
Sbjct: 655  TLNYEQNQAHYIVARVTD--NKGLFTTRRFRVTITDEND-APAGIT-LAGNSLTATVDEN 710

Query: 274  YSIVRV-QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
             +   V +    DE      TY +TD D  G             +V  S  LD E++  Y
Sbjct: 711  ANGALVGELVTIDEDSAQSHTYVLTD-DAAGR----FVTRANKLYVSRSANLDYESKNTY 765

Query: 333  QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
             + + +TD G+P  + + T                     V+  E+ P  T +  LT TD
Sbjct: 766  NITIRSTDTGNPSLNVSNTFSILVRDVNEAPSKVSLSNSRVQ--ENSPKDTVIGQLTVTD 823

Query: 393  ADED----NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448
             D       + H      +  G+F +   N   +  V   LDF+Q     + V   DSG 
Sbjct: 824  PDNSAYNSRQSHKCSVVDDMIGQFVVDQGNVLKVGRVV--LDFEQATVISVPVKCVDSGY 881

Query: 449  RSDTAMVQINIT-DANNYAPVFENAPYTASVFEDAP---IGTTVLVVSATDSDVGINAQI 504
               +  V  NIT D  N +P  + A    S+ E+ P   IGT  L  +  D++       
Sbjct: 882  PPLSLQVVFNITVDDVNESPA-DIALSGNSIAENVPATYIGT--LTTTDPDNEAQFRQTF 938

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
            TY+L  + +          FVI+    A+ + + L+ E  + ++ T+ + D G P LS T
Sbjct: 939  TYTLMGDTAGIP-------FVIDG--AALNSTRPLNYERKAFWVFTIRSTDSGTPPLSVT 989

Query: 565  TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
                I+VVDVN  E  +   + ++++ E++   T +  +   D D   +       D   
Sbjct: 990  KTFNITVVDVN--EAPYGITVSSSDVDENSGQDTVIGTLSCQDPDFDQSHSYTLIDDAGG 1047

Query: 625  R---EEGSFVIDPA-SGVIRTNKA---LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            R   E  + ++  + S  IR   +   L+ E    H ++  + D G P ++S   + I +
Sbjct: 1048 RFKVENDTLMVALSNSDCIRLGGSACKLNYEGQRQHVIRVRSTDNGAPARTSEKSLVITV 1107

Query: 678  EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
             D+ND P         F + EN+PIGT IG++ A D D+     + +S+   DD   F++
Sbjct: 1108 NDVNDRPRDLRMS--GFKVEENAPIGTRIGKLTASDEDK--YQTLSFSLV-DDDKGRFAI 1162

Query: 738  ET 739
            ++
Sbjct: 1163 DS 1164



 Score = 90.6 bits (215), Expect = 2e-17
 Identities = 171/731 (23%), Positives = 292/731 (39%), Gaps = 92/731 (12%)

Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
           A+LD E    Y + V++TD  +P    LS   T+ + I D N+     S    T++    
Sbjct: 112 ANLDFEVARSYQLRVRSTDSGTP---PLSVEGTVTITISDVNERPTNISLSASTITE--- 165

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQV 220
            +     VI ++   D D       R   +   T       ++ G+  +V +  ++YE+ 
Sbjct: 166 -NTPPGTVIGRLSVIDPDNLGPQGDRQRHVCRLTDSSNGRVAIQGNQLVVGSAGVNYERG 224

Query: 221 RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
            S  + +   D G           +++ DVN++      S  Q  + EN P    +  ++
Sbjct: 225 SSLNVTVSCADPG--GLELLASFTVDVSDVNESPTAISISSLQ--ILENRPALTKVGDLK 280

Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPIT-IDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
             D D  V    T+ +T       V  P++    R+G +  +  LD E+ A++ + + A 
Sbjct: 281 VTDPDNEVCQRQTFNLT-------VLSPLSPFKVRNGALLATRPLDFESHAQWTVRIRAQ 333

Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399
           D G P +  T +                     V+  E+    T V  L+  D D   R 
Sbjct: 334 DSGTPSKYFTESFTVRVLDDNDPPTAITLSSSAVD--ENSGIDTLVGYLSTRDEDSGQRF 391

Query: 400 HYEITGGNTRGRFSI------TSQNGRGLITVAQP---LDFKQERRYVLTVSATDSGGRS 450
            Y +   + RGRF I       +Q+ R  +        L+++  + +++ V  TDSG   
Sbjct: 392 TYTLL-DSARGRFKIEGDKLKVAQSNRECLRQGGNSCLLNYEHNQTHLIRVRTTDSGTIP 450

Query: 451 DT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
            T  A++ I I D N+     + +     V E+A IG++    S+ D D G    + YSL
Sbjct: 451 LTYDAVLTITIRDINDQPRDLQLS--NNRVAENASIGSSFGTFSSRDEDAG--QSLVYSL 506

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
           S +           +F ++   G +   K +D ET   +++     D G P++       
Sbjct: 507 SDDDGG--------RFRVD-AVGKLFKAKDMDYETQRSHVIQAVVTDNGSPAMKMEKQFT 557

Query: 569 ISVVDVNDNEPVF-------KQQLYTAN---IMEDALVGTSVSQVGATDADVGLNGRIHY 618
           I V+D+N+  PV         Q  +  N   + E++ +GT V  + A D D     ++ +
Sbjct: 558 IEVLDINE-APVHLNFTSTDGQLAFPPNSPKVRENSELGTVVGTLEALDYDA--LQQLSF 614

Query: 619 ELDPKDREEGSF-----VIDPASGV----------IRTNKALDRESVATHDLKAVAIDGG 663
            LD    E  S      +  P + +          +R N  L+ E    H + A   D  
Sbjct: 615 HLDDSAGEAFSLSASASLCVPVTNMRGFNTRCTHTLRVNTTLNYEQNQAHYIVARVTD-- 672

Query: 664 TPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
                +T    + I D ND+P       + LT  + EN+  G  +GE+   D D   +A 
Sbjct: 673 NKGLFTTRRFRVTITDENDAPAGITLAGNSLTATVDENAN-GALVGELVTIDED---SAQ 728

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778
            H  +   D +  F   TR  ++K  +    +LDYES +  Y + IR+    +P L    
Sbjct: 729 SHTYVLTDDAAGRF--VTR--ANKLYVSRSANLDYES-KNTYNITIRSTDTGNPSLNVSN 783

Query: 779 RVEILVTDVND 789
              ILV DVN+
Sbjct: 784 TFSILVRDVNE 794



 Score = 88.2 bits (209), Expect = 8e-17
 Identities = 113/501 (22%), Positives = 213/501 (42%), Gaps = 44/501 (8%)

Query: 386  VTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
            VT+T+TD   +   H  +EI     R   ++TS + +G  T +   +  +  R  +TV++
Sbjct: 1550 VTVTSTDNKGNTASHNGHEIH----RSSVTVTSTDNKGN-TASH--NGHEIYRSSVTVTS 1602

Query: 444  TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV----- 498
            TD+ G + T    I + D N+ AP   +A    ++ E +P GT +  +   D DV     
Sbjct: 1603 TDNKGLNVTNSFVITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITADQDVRQSHS 1661

Query: 499  -GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLLDRETMSGYLLTVTARDG 556
              I     Y    + ++ ++      F I   +G ++ +  LLD E  + Y LTV + D 
Sbjct: 1662 YNIEHVTAYGFGGKSNSSSLLG---LFAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDN 1718

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
            G+P LS      ++V+DV DN    +  QL  + ++E+A  G  +  + A D D      
Sbjct: 1719 GLPPLSTLGQFFVNVIDVLDNNDRPQGIQLSPSTVLENATAGAVIGSLQARDQDANQT-- 1776

Query: 616  IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
              +     DR +   + +     +    +++ E   T ++   A D G+P  S   ++ +
Sbjct: 1777 --HSFSVVDRTD---LFEVRGSKLVLVSSVNYEENPTINVTIRAADDGSPSLSKEEVLAV 1831

Query: 676  KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
             + D ND+P           + ENS  GT +  +   D D       HY     D    F
Sbjct: 1832 TVIDCNDAPSDVIIRPQNIVLPENSKSGTPLANVTVVDDD---TLQEHYCTL-IDGQRYF 1887

Query: 736  SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
             ++    S+    V   +LD+E+ ++   + ++     +P   N     + ++D+N+ AP
Sbjct: 1888 YIKKLSRSEAGIFVAASELDFETMKQPITVTVKCTDDGNPQYSNQRSFNVTLSDINE-AP 1946

Query: 793  ---VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849
                +    ++  N    + +   G +   D DV     ++++ G   N+  +N T   +
Sbjct: 1947 YDITLTGSPVVEENVVKGYAI---GSLSCKDPDVGQSHVFQVV-GKYDNVFEVNGTNLIV 2002

Query: 850  TLSPQLNTN-VPKLATMEVSV 869
                 L+   +P  AT+ +S+
Sbjct: 2003 KDPSYLDHEALPPPATLHISI 2023



 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 132/596 (22%), Positives = 236/596 (39%), Gaps = 51/596 (8%)

Query: 223  YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
            YR  +      +   + T   +I ++D ND AP   ++    +++E+ P G  I  +   
Sbjct: 1594 YRSSVTVTSTDNKGLNVTNSFVITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITA 1652

Query: 283  DAD----EGVNAE--LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL-DRETQAKYQLL 335
            D D       N E    Y    K  + ++     I+  SG +  SG L D E  A Y L 
Sbjct: 1653 DQDVRQSHSYNIEHVTAYGFGGKSNSSSLLGLFAIESPSGKLSLSGPLLDYEQYANYTLT 1712

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDAD 394
            V +TD G PP S                      Q     + E+   G  + +L A D D
Sbjct: 1713 VRSTDNGLPPLSTLGQFFVNVIDVLDNNDRPQGIQLSPSTVLENATAGAVIGSLQARDQD 1772

Query: 395  EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DT 452
             +    + +       R  +    G  L+ V+  +++++     +T+ A D G  S    
Sbjct: 1773 ANQTHSFSVVD-----RTDLFEVRGSKLVLVSS-VNYEENPTINVTIRAADDGSPSLSKE 1826

Query: 453  AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
             ++ + + D N+        P    + E++  GT +  V+  D D      +     + I
Sbjct: 1827 EVLAVTVIDCNDAPSDVIIRPQNIVLPENSKSGTPLANVTVVDDDT-----LQEHYCTLI 1881

Query: 513  SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISV 571
              +   +  +  +   + G       LD ETM   + +TV   D G P  S+     +++
Sbjct: 1882 DGQRYFYIKK--LSRSEAGIFVAASELDFETMKQPITVTVKCTDDGNPQYSNQRSFNVTL 1939

Query: 572  VDVNDNEPVFKQQLYTANIMEDALV-GTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
             D+N  E  +   L  + ++E+ +V G ++  +   D DVG +    +      + +  F
Sbjct: 1940 SDIN--EAPYDITLTGSPVVEENVVKGYAIGSLSCKDPDVGQS----HVFQVVGKYDNVF 1993

Query: 631  VIDPASGVIRTNKALDRESV---ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
             ++  + +++    LD E++   AT  +   A D G  P   T  V I + D+N++P   
Sbjct: 1994 EVNGTNLIVKDPSYLDHEALPPPATLHISIRATDNGDTPLDVTNDVTINVTDVNEAPYDI 2053

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSD 744
                    + E+   G  I ++ + +P+      V YS+         N+  L +   S 
Sbjct: 2054 RLVPSHVTVKEDIRTGQCIAQVTSTNPE--VEQTVSYSLLSYQTEFRINAVCLNSSLSSG 2111

Query: 745  KAELVTM-VDLDY---ESPRKKYELVIRAAS---PPL-WND---VRVEILVTDVND 789
             A  +T+   L Y   ES    Y++++ A     PPL WND   VRVE +   VN+
Sbjct: 2112 NAAYLTVNGPLSYDKMESLNYTYDIMVEAMDNGIPPLAWNDSVFVRVERVDPCVNE 2167



 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 105/404 (25%), Positives = 173/404 (42%), Gaps = 50/404 (12%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F IDG   AL +   L+ E+ A +   +++TD  +P    LS T T ++ ++D N+    
Sbjct: 951  FVIDG--AALNSTRPLNYERKAFWVFTIRSTDSGTPP---LSVTKTFNITVVDVNE--AP 1003

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII---GGNTQMQFS--IDS 204
            +     +  VDE+     + VI  +   D D   + +  Y +I   GG  +++    + +
Sbjct: 1004 YGITVSSSDVDENSG--QDTVIGTLSCQDPDFDQSHS--YTLIDDAGGRFKVENDTLMVA 1059

Query: 205  LSGDVSL-----VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
            LS    +        L+YE  R + + +R+ D G+P+R++   L+I + DVND       
Sbjct: 1060 LSNSDCIRLGGSACKLNYEGQRQHVIRVRSTDNGAPARTSEKSLVITVNDVNDRPRDLRM 1119

Query: 260  SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
            S F+  V EN PIG  I ++ A D D+     L++++ D D  G       ID  SG+V 
Sbjct: 1120 SGFK--VEENAPIGTRIGKLTASDEDK--YQTLSFSLVDDD-KGR----FAIDS-SGYVM 1169

Query: 320  TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX----XXXFMPGQYEVE- 374
                 D ET   + ++  A D G    +   T                   + GQ     
Sbjct: 1170 KVKATDYETSQLHTIIAQARDNGTKTLAVNQTFTIVVVNINEAPINISITSLNGQQAFPD 1229

Query: 375  ----LAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-----TRGRFSITSQNGRGLI-- 423
                ++E+ P GT V TL + D D   +L ++IT        T    + T+  G G I  
Sbjct: 1230 NAPTVSENSPNGTVVGTLFSLDHDAVQKLSFQITNNKFTLDPTPVCHNQTNIPGVGTICS 1289

Query: 424  ---TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464
                V   LD++Q  R  + V   D  G S +    + + DAN+
Sbjct: 1290 TKLRVRGGLDYEQSAREDVIVRVMDDHGLSLSQRFTVQVLDAND 1333



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 88/372 (23%), Positives = 147/372 (39%), Gaps = 40/372 (10%)

Query: 443  ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT-------VLVVSATD 495
            AT +       + + +  D +N  P  +N  ++ +V + +  G+        +  V + D
Sbjct: 1482 ATVAENSGPVVVGRFHTIDPDNEGPWAQNQTFSYTVIKQSGTGSPFSTEGDFLKTVRSLD 1541

Query: 496  SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTA 553
             +   +  +T + +    N A +H+  +   +  T   T NK           Y  +VT 
Sbjct: 1542 YETRNSWSVTVTSTDNKGNTA-SHNGHEIHRSSVTVTSTDNKGNTASHNGHEIYRSSVTV 1600

Query: 554  RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
                   L+ T    I+V D ND  P         NI E +  GT +  +   D DV  +
Sbjct: 1601 TSTDNKGLNVTNSFVITVQDRND-APTKISASGPLNIAEHSPSGTYIGTLITADQDVRQS 1659

Query: 614  GRIH------YELDPKDREE---GSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGG 663
               +      Y    K       G F I+  SG +  +   LD E  A + L   + D G
Sbjct: 1660 HSYNIEHVTAYGFGGKSNSSSLLGLFAIESPSGKLSLSGPLLDYEQYANYTLTVRSTDNG 1719

Query: 664  TPPQSSTVIVHIKIEDI---NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
             PP S+     + + D+   ND P   +    T  + EN+  G  IG ++A D D   N 
Sbjct: 1720 LPPLSTLGQFFVNVIDVLDNNDRPQGIQLSPST--VLENATAGAVIGSLQARDQD--ANQ 1775

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777
               +S+   D ++ F +   +GS   +LV +  ++YE       + IRAA   SP L  +
Sbjct: 1776 THSFSVV--DRTDLFEV---RGS---KLVLVSSVNYEE-NPTINVTIRAADDGSPSLSKE 1826

Query: 778  VRVEILVTDVND 789
              + + V D ND
Sbjct: 1827 EVLAVTVIDCND 1838



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 16/138 (11%)

Query: 210  SLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            +LV T  L++E   +   ++R  D G+P       + I ++DVN+ AP     L   +V+
Sbjct: 1428 TLVSTGDLNHEATPTIDAILRCYDDGTPRLYLEKTITIFVKDVNE-APS-GIHLAGATVA 1485

Query: 268  ENV-PIGYSIVRVQAYDAD-EG---VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
            EN  P+   + R    D D EG    N   +YT+  +  TG+   P + +    ++ T  
Sbjct: 1486 ENSGPV--VVGRFHTIDPDNEGPWAQNQTFSYTVIKQSGTGS---PFSTE--GDFLKTVR 1538

Query: 323  QLDRETQAKYQLLVTATD 340
             LD ET+  + + VT+TD
Sbjct: 1539 SLDYETRNSWSVTVTSTD 1556



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 38/120 (31%), Positives = 54/120 (45%), Gaps = 16/120 (13%)

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PIG 703
            L+ E+  T D      D GTP       + I ++D+N++P        T  ++ENS P+ 
Sbjct: 1435 LNHEATPTIDAILRCYDDGTPRLYLEKTITIFVKDVNEAPSGIHLAGAT--VAENSGPV- 1491

Query: 704  TTIGEIRAHDPD-EGP---NAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
              +G     DPD EGP   N    Y+ IK     + FS E   G     L T+  LDYE+
Sbjct: 1492 -VVGRFHTIDPDNEGPWAQNQTFSYTVIKQSGTGSPFSTE---GD---FLKTVRSLDYET 1544



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGA-ECSDLWDTYICDCKEGHTGKDC 1348
            C  + + C  +PC   A +C D    + C C+EG+TG  C
Sbjct: 2260 CSREINECEPSPCGQYALDCKDGIARFECICQEGYTGTVC 2299


>SB_56813| Best HMM Match : Cadherin (HMM E-Value=5.8e-40)
          Length = 211

 Score =  137 bits (331), Expect = 1e-31
 Identities = 83/212 (39%), Positives = 119/212 (56%), Gaps = 13/212 (6%)

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           +DT +V+I ITD N+  P+FE   Y  SV E A  G  +L VSA D D G+NA+++Y +S
Sbjct: 3   TDT-IVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYIS 61

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
               N A       F +N + G I     LDRE +  Y LT+TA+DG     S    V +
Sbjct: 62  EGNINGA-------FEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNV 111

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            V+D+NDN P F++  Y  N+ E+   GT V ++ A+D D+G +G+  Y++  +     +
Sbjct: 112 YVLDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGL--SA 169

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAID 661
           F I+P +G IRT   LDRE  A +D  A AID
Sbjct: 170 FTINPLTGEIRTRIKLDRELKARYDFIAFAID 201



 Score =  123 bits (296), Expect = 2e-27
 Identities = 72/205 (35%), Positives = 108/205 (52%), Gaps = 10/205 (4%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           + + I D+NDN P F EK Y +SV E  S      + K+ A D D G N+ + Y I  GN
Sbjct: 7   VEIIITDENDNPPIFEEKVYNISVLE--SAASGMELLKVSAVDRDFGVNARVSYYISEGN 64

Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
               F ++   G + L  TLD E V  Y+L + A+DG     S    + + + D+NDN P
Sbjct: 65  INGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNVYVLDINDNNP 121

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
           +F  S ++ +VSEN P G  +V+++A D D G + +  Y     D +G      TI+P +
Sbjct: 122 KFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLY-----DISGQGLSAFTINPLT 176

Query: 316 GWVYTSGQLDRETQAKYQLLVTATD 340
           G + T  +LDRE +A+Y  +  A D
Sbjct: 177 GEIRTRIKLDRELKARYDFIAFAID 201



 Score =  116 bits (279), Expect = 3e-25
 Identities = 72/212 (33%), Positives = 111/212 (52%), Gaps = 12/212 (5%)

Query: 564 TTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           TTD  VEI + D NDN P+F++++Y  +++E A  G  + +V A D D G+N R+ Y + 
Sbjct: 2   TTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYIS 61

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
            +    G+F ++   G IR    LDRE+V  + L   A DG     S    V++ + DIN
Sbjct: 62  -EGNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNVYVLDIN 117

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D+ P FE       +SEN P GT + ++RA DPD G +    Y I  G   ++F++    
Sbjct: 118 DNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDI-SGQGLSAFTINPLT 176

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPP 773
           G    E+ T + LD E  + +Y+ +  A   P
Sbjct: 177 G----EIRTRIKLDREL-KARYDFIAFAIDSP 203



 Score = 92.7 bits (220), Expect = 4e-18
 Identities = 66/222 (29%), Positives = 104/222 (46%), Gaps = 28/222 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I + D ND+ P+FE + Y  SV E A+SG  +L + A D+D G NA V Y I       
Sbjct: 8   EIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYIS------ 61

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                           +   F ++   G +    +LDRE V  Y + + A D       +
Sbjct: 62  -------------EGNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKD------GK 102

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S  AT++V ++D NDN P+F +  Y V+V E+       ++ K++A+D D+G +    Y
Sbjct: 103 YSGEATVNVYVLDINDNNPKFEKSHYRVNVSENRPA--GTLVVKLRASDPDLGESGKFLY 160

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
             I G     F+I+ L+G++     LD E    Y  +  A D
Sbjct: 161 D-ISGQGLSAFTINPLTGEIRTRIKLDRELKARYDFIAFAID 201



 Score = 92.3 bits (219), Expect = 5e-18
 Identities = 68/215 (31%), Positives = 102/215 (47%), Gaps = 12/215 (5%)

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           ++  T + I I D NDN P F   ++  SV E+   G  +++V A D D GVNA ++Y +
Sbjct: 1   KTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYI 60

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           ++    GN++    ++   G +  +G LDRE    Y+L +TA DG     S  AT     
Sbjct: 61  SE----GNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNVYV 113

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414
                    F    Y V ++E+ P GT VV L A+D D  E  +  Y+I+G   +G  + 
Sbjct: 114 LDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISG---QGLSAF 170

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
           T     G I     LD + + RY     A DS G+
Sbjct: 171 TINPLTGEIRTRIKLDRELKARYDFIAFAIDSPGK 205



 Score = 86.2 bits (204), Expect = 3e-16
 Identities = 59/179 (32%), Positives = 91/179 (50%), Gaps = 13/179 (7%)

Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           Y + + E    G  ++ ++A D D   + R+ Y I+ GN  G F +  + G   I +A  
Sbjct: 26  YNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAFEVNREFGT--IRLAGT 83

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           LD +    Y LT++A D G  S  A V + + D N+  P FE + Y  +V E+ P GT V
Sbjct: 84  LDRENVDHYKLTLTAKD-GKYSGEATVNVYVLDINDNNPKFEKSHYRVNVSENRPAGTLV 142

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           + + A+D D+G + +  Y    +IS + ++     F INP TG I T   LDRE  + Y
Sbjct: 143 VKLRASDPDLGESGKFLY----DISGQGLS----AFTINPLTGEIRTRIKLDRELKARY 193



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 49/185 (26%), Positives = 84/185 (45%), Gaps = 8/185 (4%)

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           +++  IV I I D ND+PP+FE       + E++  G  + ++ A D D G NA V Y I
Sbjct: 1   KTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYI 60

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786
             G+ + +F +    G+    +     LD E+    Y+L + A       +  V + V D
Sbjct: 61  SEGNINGAFEVNREFGT----IRLAGTLDRENV-DHYKLTLTAKDGKYSGEATVNVYVLD 115

Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRI-LSGNNANLILLNE 844
           +NDN P  +       N  +  P G    ++ A D D+ +  ++   +SG   +   +N 
Sbjct: 116 INDNNPKFEKSHYRV-NVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLSAFTINP 174

Query: 845 TTGSM 849
            TG +
Sbjct: 175 LTGEI 179


>SB_30491| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1516

 Score =  136 bits (330), Expect = 2e-31
 Identities = 100/307 (32%), Positives = 149/307 (48%), Gaps = 12/307 (3%)

Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           Y   ++E+      ++ +TA DAD  E+ RL+Y I  GNT   F++ +  G   + + + 
Sbjct: 452 YNKVISENTTVDATILRVTANDADSGENARLNYAIETGNTNDTFALDTSTGE--LRLHKS 509

Query: 429 LDFKQERRYVLTVSATDSGGRSDTA-----MVQINITDAN-NYAPVFENAPYTASVFEDA 482
           L  K    Y LT++A D G  + T+      +++   D+     P F    Y A+V E  
Sbjct: 510 LRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDSGPTKRPTFPVPIYLATVNEST 569

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           P+ T +L V A + +      I+Y LS     +     D  F +N QTGAI  NK LD E
Sbjct: 570 PLYTEILRVRARN-ERKYEGSISYFLSHISGGDKEGDVDLHFGVNSQTGAIRLNKKLDYE 628

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y+  V A D    S  DT  V I V DVNDN P F Q  Y+   +++  +  +V  
Sbjct: 629 KTKRYVFLVGAIDVRTASPVDTVLVRILVQDVNDNRPEFYQYRYSRVFLKEPPLYYAVDT 688

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A DAD G NGR+ Y +     E   F ID  +GV++T++ L R+++   +L     D 
Sbjct: 689 VMAKDADSGQNGRLSYWIS-GGNEGNFFAIDSRTGVVKTSRMLQRQTLRLFNLTISVADQ 747

Query: 663 GTPPQSS 669
           G+PP  S
Sbjct: 748 GSPPMKS 754



 Score =  130 bits (313), Expect = 2e-29
 Identities = 96/344 (27%), Positives = 161/344 (46%), Gaps = 27/344 (7%)

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           ++I + D+NDN PRF   ++ + +SEN  +  +I+RV A DAD G NA L Y +     T
Sbjct: 433 VIIRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIE----T 488

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           GN +    +D  +G +     L  +    Y L +TA D G+P  ++              
Sbjct: 489 GNTNDTFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDS 548

Query: 363 XXXFMP----GQYEVELAEDEPPGTPVVTLTA-TDADEDNRLHY---EITGGNTRG---- 410
                P      Y   + E  P  T ++ + A  +   +  + Y    I+GG+  G    
Sbjct: 549 GPTKRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLSHISGGDKEGDVDL 608

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPV 468
            F + SQ   G I + + LD+++ +RYV  V A D  +    DT +V+I + D N+  P 
Sbjct: 609 HFGVNSQT--GAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRILVQDVNDNRPE 666

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           F    Y+    ++ P+   V  V A D+D G N +++Y +S    NE        F I+ 
Sbjct: 667 FYQYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISG--GNEG-----NFFAIDS 719

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
           +TG + T+++L R+T+  + LT++  D G P +    D  + V+
Sbjct: 720 RTGVVKTSRMLQRQTLRLFNLTISVADQGSPPMKSEKDALVQVL 763



 Score =  125 bits (302), Expect = 4e-28
 Identities = 98/340 (28%), Positives = 148/340 (43%), Gaps = 28/340 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ P F +  Y   + E  +   T+L + A D D G+NA + Y IE  T +T 
Sbjct: 435 IRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIE--TGNT- 491

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            D F +D  +G L    SL  +    Y + + A DQ  P     
Sbjct: 492 ----------------NDTFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSD 535

Query: 131 SSTATIHVNIIDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                I V   D      P F    Y  +V+E   +    +  + +      G+ S    
Sbjct: 536 PVHVFIKVQRHDSGPTKRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLS 595

Query: 190 AIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            I GG+ +    + F ++S +G + L K LDYE+ + Y  ++ A D  + S  +T  + I
Sbjct: 596 HISGGDKEGDVDLHFGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRI 655

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            ++DVNDN P FY   +     +  P+ Y++  V A DAD G N  L+Y ++     GN 
Sbjct: 656 LVQDVNDNRPEFYQYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISG----GNE 711

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
                ID R+G V TS  L R+T   + L ++  D G PP
Sbjct: 712 GNFFAIDSRTGVVKTSRMLQRQTLRLFNLTISVADQGSPP 751



 Score =  120 bits (290), Expect = 1e-26
 Identities = 87/300 (29%), Positives = 143/300 (47%), Gaps = 18/300 (6%)

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
           A+V I + D N+  P F    Y   + E+  +  T+L V+A D+D G NA++ Y++ +  
Sbjct: 431 ALVIIRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIETGN 490

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SDTTDVEISV 571
           +N+        F ++  TG +  +K L  +    Y LT+TA+D G P++ SD   V I V
Sbjct: 491 TNDT-------FALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKV 543

Query: 572 VDVNDN---EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL------DP 622
              +      P F   +Y A + E   + T + +V A + +    G I Y L      D 
Sbjct: 544 QRHDSGPTKRPTFPVPIYLATVNESTPLYTEILRVRARN-ERKYEGSISYFLSHISGGDK 602

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
           +   +  F ++  +G IR NK LD E    +     AID  T     TV+V I ++D+ND
Sbjct: 603 EGDVDLHFGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRILVQDVND 662

Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           + P F     +    +  P+   +  + A D D G N  + Y I GG++ N F++++R G
Sbjct: 663 NRPEFYQYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDSRTG 722



 Score =  119 bits (286), Expect = 4e-26
 Identities = 90/322 (27%), Positives = 155/322 (48%), Gaps = 12/322 (3%)

Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
           A + + + D NDN P+F    Y   + E+ +V  +  I ++ A DAD G N+ + YAI  
Sbjct: 431 ALVIIRVDDLNDNKPRFVLPVYNKVISENTTV--DATILRVTANDADSGENARLNYAIET 488

Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVND 252
           GNT   F++D+ +G++ L K+L  +    Y L + A+D G P+  S+   + I ++  + 
Sbjct: 489 GNTNDTFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDS 548

Query: 253 ---NAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD--EGVNAELTYTMTDKDYTGNVDL 307
                P F   ++  +V+E+ P+   I+RV+A +    EG  +     ++  D  G+VDL
Sbjct: 549 GPTKRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLSHISGGDKEGDVDL 608

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              ++ ++G +  + +LD E   +Y  LV A D        T                F 
Sbjct: 609 HFGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVDTVLVRILVQDVNDNRPEFY 668

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
             +Y     ++ P    V T+ A DAD  ++ RL Y I+GGN    F+I S+   G++  
Sbjct: 669 QYRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDSRT--GVVKT 726

Query: 426 AQPLDFKQERRYVLTVSATDSG 447
           ++ L  +  R + LT+S  D G
Sbjct: 727 SRMLQRQTLRLFNLTISVADQG 748



 Score =  119 bits (286), Expect = 4e-26
 Identities = 101/352 (28%), Positives = 163/352 (46%), Gaps = 17/352 (4%)

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
           V I V D+NDN+P F   +Y   I E+  V  ++ +V A DAD G N R++Y ++  +  
Sbjct: 433 VIIRVDDLNDNKPRFVLPVYNKVISENTTVDATILRVTANDADSGENARLNYAIETGNTN 492

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSP- 684
           + +F +D ++G +R +K+L  +    ++L   A D G P  +S  + V IK++  +  P 
Sbjct: 493 D-TFALDTSTGELRLHKSLRGKHYYFYNLTLTAKDQGEPAMTSDPVHVFIKVQRHDSGPT 551

Query: 685 --PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY--SIKGGDDSNSFSLETR 740
             P F        ++E++P+ T I  +RA +  +   ++ ++   I GGD      L   
Sbjct: 552 KRPTFPVPIYLATVNESTPLYTEILRVRARNERKYEGSISYFLSHISGGDKEGDVDLHFG 611

Query: 741 QGSDKAELVTMVDLDYESPRKKYELV----IRAASPPLWNDVRVEILVTDVNDNAPVMKD 796
             S    +     LDYE  ++   LV    +R ASP   + V V ILV DVNDN P    
Sbjct: 612 VNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPV--DTVLVRILVQDVNDNRPEFYQ 669

Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
           ++      K+         V A DAD     +L Y I  GN  N   ++  TG +  S  
Sbjct: 670 YRYSRVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDSRTGVVKTSRM 729

Query: 855 LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVR-LITEEMLLNSITVRLNDMT 904
           L     +L  + +SV D G   +K+     V+ LI   + L+   V  ++ T
Sbjct: 730 LQRQTLRLFNLTISVADQGSPPMKSEKDALVQVLIFHPISLHMTLVETSETT 781



 Score =  112 bits (269), Expect = 4e-24
 Identities = 105/371 (28%), Positives = 168/371 (45%), Gaps = 37/371 (9%)

Query: 403 ITGGNTRGRFSITS--QNGRGLITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINI 459
           +T GN    F + +  +N    + + + LD +    Y LT+ A +    +   A ++I +
Sbjct: 25  VTSGNEESIFKLINYPRNNSASLILQRELDREVASGYNLTIKALNIHENKFRLAHIRIVV 84

Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
            D N+ AP F  + Y  ++F +   G  +  V+A D D G NA I Y L          +
Sbjct: 85  IDENDNAPTFPPSGYHTTIFTNVTEGQEIFRVNAIDVDTGDNANIRYHL---------LN 135

Query: 520 HDQQFVINPQTGAIT-TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
           H Q F I P+TG +  T +    +    + + V A +G   ++   T   I+V  VN+  
Sbjct: 136 HQQLFSIMPKTGVLVKTKERFAIDRTRNFTVIVVAINGEFKNVGTVT---ITVHPVNERR 192

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           P F ++ Y   + E   VGTSV++V A D D G  G++ Y +  +      F ID   GV
Sbjct: 193 PTFLKRNYEVKVSEAVQVGTSVAKVFAADPDYGNLGKLRYSILTESCP--FFGIDD-DGV 249

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTP----PQSSTVIVHIK-IEDINDSPPVFESDCLT 693
           IR  + L R       L+  A D G P    P+ +TV + I+ +E++    PV+E     
Sbjct: 250 IRNVQPLTRHGGENCTLEITAQDSGIPPLETPRPATVSIVIEPVENLKFDVPVYE----- 304

Query: 694 FYISENSPIGTTIGEIRA---HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
             I EN  +G+ I  +RA         P  +V YSI+  D + SF +    G     + T
Sbjct: 305 ISIPENIILGSEILTVRAVAGSGNRRNPRKIV-YSIENIDGALSFKI----GKHTGRITT 359

Query: 751 MVDLDYESPRK 761
              +DYE  ++
Sbjct: 360 RTHIDYEKTKE 370



 Score =  101 bits (243), Expect = 6e-21
 Identities = 90/347 (25%), Positives = 149/347 (42%), Gaps = 24/347 (6%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           S +L+ +  LDRE  + Y + +KA +    + +     A I + +ID+NDN P F    Y
Sbjct: 44  SASLILQRELDREVASGYNLTIKALN----IHENKFRLAHIRIVVIDENDNAPTFPPSGY 99

Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215
             ++  +  VT+   I ++ A D D G N+ IRY ++  N Q  FSI   +G   LVKT 
Sbjct: 100 HTTIFTN--VTEGQEIFRVNAIDVDTGDNANIRYHLL--NHQQLFSIMPKTG--VLVKTK 153

Query: 216 D---YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
           +    ++ R++ +++ A +G      N   + I +  VN+  P F    ++  VSE V +
Sbjct: 154 ERFAIDRTRNFTVIVVAING---EFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQV 210

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G S+ +V A D D G   +L Y++  +        P       G +     L R      
Sbjct: 211 GTSVAKVFAADPDYGNLGKLRYSILTE------SCPFFGIDDDGVIRNVQPLTRHGGENC 264

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
            L +TA D G PP                    F    YE+ + E+   G+ ++T+ A  
Sbjct: 265 TLEITAQDSGIPPLETPRPATVSIVIEPVENLKFDVPVYEISIPENIILGSEILTVRAVA 324

Query: 393 ADEDNRLHYEITGG--NTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
              + R   +I     N  G  S       G IT    +D+++ + Y
Sbjct: 325 GSGNRRNPRKIVYSIENIDGALSFKIGKHTGRITTRTHIDYEKTKEY 371



 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 79/328 (24%), Positives = 138/328 (42%), Gaps = 38/328 (11%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H +I V+D ND++P F    Y  ++    + G  +  + A D D G NA + Y +     
Sbjct: 79  HIRIVVIDENDNAPTFPPSGYHTTIFTNVTEGQEIFRVNAIDVDTGDNANIRYHL----- 133

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALL-TRASLDREKVARYTVLVKATDQASPV 126
             LN               Q +F I  ++G L+ T+     ++   +TV+V A      +
Sbjct: 134 --LNH--------------QQLFSIMPKTGVLVKTKERFAIDRTRNFTVIVVA------I 171

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
           +    +  T+ + +   N+  P F ++ Y V V E + V  +  +AK+ A D D G    
Sbjct: 172 NGEFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQVGTS--VAKVFAADPDYGNLGK 229

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           +RY+I+  +    F ID   G +  V+ L      +  L I AQD G P         ++
Sbjct: 230 LRYSILTESCPF-FGIDD-DGVIRNVQPLTRHGGENCTLEITAQDSGIPPLETPRPATVS 287

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I        +F   +++ S+ EN+ +G  I  VR  A   +     ++ Y++ + D    
Sbjct: 288 IVIEPVENLKFDVPVYEISIPENIILGSEILTVRAVAGSGNRRNPRKIVYSIENIDGA-- 345

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKY 332
             L   I   +G + T   +D E   +Y
Sbjct: 346 --LSFKIGKHTGRITTRTHIDYEKTKEY 371



 Score = 76.6 bits (180), Expect = 3e-13
 Identities = 52/163 (31%), Positives = 79/163 (48%), Gaps = 15/163 (9%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVSDRLSSTATIHVNIIDDNDNY 147
           F ++ ++GA+     LD EK  RY  LV A D   ASPV      T  + + + D NDN 
Sbjct: 610 FGVNSQTGAIRLNKKLDYEKTKRYVFLVGAIDVRTASPVD-----TVLVRILVQDVNDNR 664

Query: 148 PQFSEKTYTVSVDEDISVTDNPV---IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
           P+F +  Y+      + + + P+   +  + A DAD G N  + Y I GGN    F+IDS
Sbjct: 665 PEFYQYRYS-----RVFLKEPPLYYAVDTVMAKDADSGQNGRLSYWISGGNEGNFFAIDS 719

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +G V   + L  + +R + L I   D GSP   +    L+ +
Sbjct: 720 RTGVVKTSRMLQRQTLRLFNLTISVADQGSPPMKSEKDALVQV 762



 Score = 74.1 bits (174), Expect = 1e-12
 Identities = 95/349 (27%), Positives = 136/349 (38%), Gaps = 28/349 (8%)

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
           S  + L + LD E    Y L I+A +    ++     + I + D NDNAP F  S +  +
Sbjct: 44  SASLILQRELDREVASGYNLTIKALNIHE-NKFRLAHIRIVVIDENDNAPTFPPSGYHTT 102

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG-WVYTSGQL 324
           +  NV  G  I RV A D D G NA + Y +       N     +I P++G  V T  + 
Sbjct: 103 IFTNVTEGQEIFRVNAIDVDTGDNANIRYHLL------NHQQLFSIMPKTGVLVKTKERF 156

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
             +    + ++V A +G         T              F+   YEV+++E    GT 
Sbjct: 157 AIDRTRNFTVIVVAING---EFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQVGTS 213

Query: 385 VVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           V  + A D D  N  +L Y I    +   F I      G+I   QPL         L ++
Sbjct: 214 VAKVFAADPDYGNLGKLRYSIL-TESCPFFGIDDD---GVIRNVQPLTRHGGENCTLEIT 269

Query: 443 ATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           A DSG         A V I I    N    F+   Y  S+ E+  +G+ +L V A     
Sbjct: 270 AQDSGIPPLETPRPATVSIVIEPVENLK--FDVPVYEISIPENIILGSEILTVRAVAGSG 327

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
             N +    +   I N   A     F I   TG ITT   +D E    Y
Sbjct: 328 --NRRNPRKIVYSIENIDGA---LSFKIGKHTGRITTRTHIDYEKTKEY 371



 Score = 74.1 bits (174), Expect = 1e-12
 Identities = 85/372 (22%), Positives = 137/372 (36%), Gaps = 23/372 (6%)

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           +LDRE  + Y L + A +  +  +   A               F P  Y   +  +   G
Sbjct: 52  ELDREVASGYNLTIKALNIHEN-KFRLAHIRIVVIDENDNAPTFPPSGYHTTIFTNVTEG 110

Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
             +  + A D D  +  +      N +  FSI  + G  L+   +     + R + + V 
Sbjct: 111 QEIFRVNAIDVDTGDNANIRYHLLNHQQLFSIMPKTGV-LVKTKERFAIDRTRNFTVIVV 169

Query: 443 ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           A + G   +   V I +   N   P F    Y   V E   +GT+V  V A D D G   
Sbjct: 170 AIN-GEFKNVGTVTITVHPVNERRPTFLKRNYEVKVSEAVQVGTSVAKVFAADPDYGNLG 228

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           ++ YS+ +E            F      G I   + L R       L +TA+D G+P L 
Sbjct: 229 KLRYSILTESC---------PFFGIDDDGVIRNVQPLTRHGGENCTLEITAQDSGIPPLE 279

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG--RIHYEL 620
                 +S+V        F   +Y  +I E+ ++G+ +  V A           +I Y +
Sbjct: 280 TPRPATVSIVIEPVENLKFDVPVYEISIPENIILGSEILTVRAVAGSGNRRNPRKIVYSI 339

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
           +  D    SF I   +G I T   +D E    +           P QS  ++  +    I
Sbjct: 340 ENIDGAL-SFKIGKHTGRITTRTHIDYEKTKEYSFP--------PKQSCDLLAQVPYCHI 390

Query: 681 NDSPPVFESDCL 692
             SP + + DCL
Sbjct: 391 AHSPDLLDVDCL 402



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 31/124 (25%), Positives = 48/124 (38%), Gaps = 3/124 (2%)

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEIL 783
           +  G++ + F L     ++ A L+   +LD E     Y L I+A +     +    + I+
Sbjct: 25  VTSGNEESIFKLINYPRNNSASLILQRELDREVA-SGYNLTIKALNIHENKFRLAHIRIV 83

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLN 843
           V D NDNAP           + +        RV A D D  D    R    N+  L  + 
Sbjct: 84  VIDENDNAPTFPPSGYHTTIFTNVTEGQEIFRVNAIDVDTGDNANIRYHLLNHQQLFSIM 143

Query: 844 ETTG 847
             TG
Sbjct: 144 PKTG 147


>SB_28202| Best HMM Match : Cadherin (HMM E-Value=1.8e-29)
          Length = 242

 Score =  133 bits (321), Expect = 2e-30
 Identities = 76/196 (38%), Positives = 107/196 (54%), Gaps = 10/196 (5%)

Query: 400 HYEITGGNT---RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456
           H+ ++GGN        S+ S NG  L   + PLD +   ++VL +S T+ G       V 
Sbjct: 54  HFNVSGGNFTFFNSSGSMFSINGNNLRVGSTPLDRETAAQHVLDISLTEGGTIKGFVKVT 113

Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
           +N+ D N+  P+F++  +  SV E   +GT  L VSATD D G N+ +TYS+       A
Sbjct: 114 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------A 166

Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576
             + +  F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ TT V I V D ND
Sbjct: 167 AGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDAND 226

Query: 577 NEPVFKQQLYTANIME 592
           N PV +  +   ++ E
Sbjct: 227 NPPVIQDAVIRVSLSE 242



 Score =  108 bits (259), Expect = 7e-23
 Identities = 62/180 (34%), Positives = 98/180 (54%), Gaps = 8/180 (4%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F I+G +   +    LDRE  A++ + +  T+  +     +     + VN++D ND  P
Sbjct: 71  MFSINGNN-LRVGSTPLDRETAAQHVLDISLTEGGT-----IKGFVKVTVNVLDINDETP 124

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G 
Sbjct: 125 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 182

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    ++ + S+SE
Sbjct: 183 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242



 Score =  107 bits (258), Expect = 1e-22
 Identities = 57/160 (35%), Positives = 89/160 (55%), Gaps = 3/160 (1%)

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRET + ++L ++  +GG  ++     V ++V+D+ND  P+F+   +  ++ E   +GT
Sbjct: 86  LDRETAAQHVLDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 143

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
               V ATD D G N  + Y +     EEG F I+  +G I   K LDRE+   + L  +
Sbjct: 144 VFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVM 202

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           A DGG PP +ST  V I++ D ND+PPV +   +   +SE
Sbjct: 203 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242



 Score = 84.2 bits (199), Expect = 1e-15
 Identities = 74/239 (30%), Positives = 116/239 (48%), Gaps = 29/239 (12%)

Query: 115 VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTD-NPV 170
           V+V  TD  SP    L S A + +++       P+    TY VSV E   ++ V D  PV
Sbjct: 1   VVVNVTDGGSPA---LKSRAMVVIDVT------PKPRNLTYDVSVLEGEANVQVMDLKPV 51

Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
           ++    +    G N    +     +  M FSI+  +  V     LD E    + L I   
Sbjct: 52  VSHFNVS----GGN----FTFFNSSGSM-FSINGNNLRVGSTP-LDRETAAQHVLDISLT 101

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           +GG+       ++ +N+ D+ND  P F +  F  SV+E   +G   + V A D D G N+
Sbjct: 102 EGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANS 159

Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
            LTY++      GN +   +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T
Sbjct: 160 ALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 214



 Score = 83.8 bits (198), Expect = 2e-15
 Identities = 54/155 (34%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           LDRE+ A H L     +GGT      V V + + DIND  P+F+S      ++E   +GT
Sbjct: 86  LDRETAAQHVLDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 143

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
               + A D D G N+ + YSI  G++   FS+  + G+    +     LD E+ R +Y 
Sbjct: 144 VFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYT 198

Query: 765 LVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796
           L + A     PPL +   V I V D NDN PV++D
Sbjct: 199 LTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 233



 Score = 75.8 bits (178), Expect = 5e-13
 Identities = 57/164 (34%), Positives = 79/164 (48%), Gaps = 8/164 (4%)

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           S  LDRET A++ L ++ T+GG        T              F    + V + E E 
Sbjct: 83  STPLDRETAAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPL--FQSPSFNVSVNEIER 140

Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
            GT  +T++ATD D   ++ L Y I  GN  G FSI   N  G I+VA+ LD +   +Y 
Sbjct: 141 LGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSI--NNKTGAISVAKQLDRETRDQYT 198

Query: 439 LTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           LTV A D G    + T  V I + DAN+  PV ++A    S+ E
Sbjct: 199 LTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242



 Score = 72.1 bits (169), Expect = 6e-12
 Identities = 48/151 (31%), Positives = 70/151 (46%), Gaps = 22/151 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I        
Sbjct: 114 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 165

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +  F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 166 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 211

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161
           +ST  + + + D NDN P   +    VS+ E
Sbjct: 212 NSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 242



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 12/173 (6%)

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
           GE      D  P  V H+++ GG+ +   +S S+ +  G++    V    LD E+  +  
Sbjct: 39  GEANVQVMDLKP-VVSHFNVSGGNFTFFNSSGSMFSINGNNLR--VGSTPLDRETAAQHV 95

Query: 764 ELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDA 821
             +       +   V+V + V D+ND  P+ +   F +  N  +    V  F  V A D 
Sbjct: 96  LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDG 153

Query: 822 DV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           D      L Y I +GN      +N  TG+++++ QL+       T+ V   DG
Sbjct: 154 DAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 206


>SB_4130| Best HMM Match : Cadherin (HMM E-Value=9.3e-29)
          Length = 322

 Score =  124 bits (298), Expect = 1e-27
 Identities = 105/328 (32%), Positives = 164/328 (50%), Gaps = 39/328 (11%)

Query: 375 LAEDEPPGTPVVT-----LTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLITVA 426
           + E  P GT V+      L A   D+D   ++L YEI   + R  FSI      G IT A
Sbjct: 3   VTEGSPQGTAVLDHKGSQLVAVATDQDISGDKLTYEIVETSARDVFSI--HPATGAITTA 60

Query: 427 QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           + LD++   +Y   +  TDSG    S  A V+I++TD N+ APVF  + Y A+V+  +  
Sbjct: 61  KVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYA 120

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDRE 542
           GT V +V+ATD D   N  +T+SL+ +          + F +NP TG +T +   LL R+
Sbjct: 121 GTRVTMVTATDGDSAAN--LTFSLARQ--------DTELFAVNPLTGVVTVSNAALLRRD 170

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
           T   Y + +T  DG   + +    V I   ++  ++  F ++ Y+A++ E   V + +  
Sbjct: 171 T---YTIKLTVSDG---NHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSVDSELVT 224

Query: 603 VGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGV--IRTNKALDRESVATHDLKAVA 659
           V A    +G    I Y  ++P +     F I P++GV  IR    LDRES+  + +   A
Sbjct: 225 VRALGYPIG--STITYTIINPSE----LFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQA 278

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVF 687
            D   PP  +   VH+++ D ND+ PVF
Sbjct: 279 RDDSVPPNVAQAAVHVQVIDRNDNQPVF 306



 Score =  105 bits (253), Expect = 4e-22
 Identities = 100/327 (30%), Positives = 149/327 (45%), Gaps = 35/327 (10%)

Query: 478 VFEDAPIGTTVL-------VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
           V E +P GT VL       V  ATD D+    ++TY +    + +        F I+P T
Sbjct: 3   VTEGSPQGTAVLDHKGSQLVAVATDQDIS-GDKLTYEIVETSARDV-------FSIHPAT 54

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
           GAITT K+LD E    Y   +   D G P LS   DV+I V D+ND  PVF    Y A +
Sbjct: 55  GAITTAKVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATV 114

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKALDRES 649
              +  GT V+ V ATD D   N  + + L  +D E   F ++P +GV+  +N AL R  
Sbjct: 115 YLPSYAGTRVTMVTATDGDSAAN--LTFSLARQDTE--LFAVNPLTGVVTVSNAALLRRD 170

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
             T+ +K    DG     ++   V I+ E++  S   F     +  + E   + + +  +
Sbjct: 171 --TYTIKLTVSDGN---HTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSVDSELVTV 225

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           RA     G  + + Y+I   + S  F +    G     +    DLD ES    Y+++++A
Sbjct: 226 RALGYPIG--STITYTII--NPSELFHIVPSTG--VMSIRAGFDLDRES-IDAYQVIVQA 278

Query: 770 ---ASPPLWNDVRVEILVTDVNDNAPV 793
              + PP      V + V D NDN PV
Sbjct: 279 RDDSVPPNVAQAAVHVQVIDRNDNQPV 305



 Score = 91.9 bits (218), Expect = 7e-18
 Identities = 87/329 (26%), Positives = 146/329 (44%), Gaps = 28/329 (8%)

Query: 266 VSENVPIGYSIV-----RVQAYDADEGVNAE-LTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           V+E  P G +++     ++ A   D+ ++ + LTY + +   T   D+  +I P +G + 
Sbjct: 3   VTEGSPQGTAVLDHKGSQLVAVATDQDISGDKLTYEIVE---TSARDV-FSIHPATGAIT 58

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
           T+  LD E   +Y   +  TD G+P  SA A               F    Y   +    
Sbjct: 59  TAKVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPS 118

Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
             GT V  +TATD D    L + +   +T   F++    G  ++TV+     +++  Y +
Sbjct: 119 YAGTRVTMVTATDGDSAANLTFSLARQDTE-LFAVNPLTG--VVTVSNAALLRRDT-YTI 174

Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            ++ +D G  +  A V+I   +  +    F    Y+ASV E   + + ++ V A    +G
Sbjct: 175 KLTVSD-GNHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIG 233

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETMSGYLLTVTARDGG 557
             + ITY+         + +  + F I P TG  +I     LDRE++  Y + V ARD  
Sbjct: 234 --STITYT---------IINPSELFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDS 282

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           VP       V + V+D NDN+PVF    Y
Sbjct: 283 VPPNVAQAAVHVQVIDRNDNQPVFINSPY 311



 Score = 89.0 bits (211), Expect = 5e-17
 Identities = 82/303 (27%), Positives = 126/303 (41%), Gaps = 20/303 (6%)

Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
           ATD D+  +  + Y I+  + +  FSI   +G ++  K LDYE    Y   I+  D G+P
Sbjct: 25  ATDQDISGDK-LTYEIVETSARDVFSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP 83

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
             S    + I++ D+ND AP F  S +  +V      G  +  V A D D   N  LT++
Sbjct: 84  RLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN--LTFS 141

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXX 353
           +  +D     +L   ++P +G V  S    L R+T   Y + +T +DG     +A A   
Sbjct: 142 LARQD----TEL-FAVNPLTGVVTVSNAALLRRDT---YTIKLTVSDGN---HTAHARVR 190

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413
                       F    Y   + E     + +VT+ A      + + Y I   N    F 
Sbjct: 191 IRCENLPSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIGSTITYTII--NPSELFH 248

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFEN 471
           I    G   I     LD +    Y + V A D     + A   V + + D N+  PVF N
Sbjct: 249 IVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQPVFIN 308

Query: 472 APY 474
           +PY
Sbjct: 309 SPY 311



 Score = 82.2 bits (194), Expect = 5e-15
 Identities = 85/321 (26%), Positives = 146/321 (45%), Gaps = 35/321 (10%)

Query: 32  VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91
           V EG+  GT VL  K      G       T + ++ D L  E             +DVF 
Sbjct: 3   VTEGSPQGTAVLDHK------GSQLVAVATDQDISGDKLTYE-------IVETSARDVFS 49

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           I   +GA+ T   LD E   +Y   +K TD  +P   RLS+ A + +++ D ND  P FS
Sbjct: 50  IHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP---RLSAFADVKIHVTDINDIAPVFS 106

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
             TY  +V   +       +  + ATD D  AN  + +++   +T++ F+++ L+G V+ 
Sbjct: 107 ASTYHATV--YLPSYAGTRVTMVTATDGDSAAN--LTFSLARQDTEL-FAVNPLTGVVT- 160

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
           V      +  +Y + +   DG   + +   ++ I   ++  +  +F    +  SV E V 
Sbjct: 161 VSNAALLRRDTYTIKLTVSDGNHTAHA---RVRIRCENLPSSDLQFSRKNYSASVREGVS 217

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT--IDPRSGWVYTSGQLDRETQ 329
           +   +V V+A      + + +TYT+ +     ++ +P T  +  R+G+      LDRE+ 
Sbjct: 218 VDSELVTVRALGYP--IGSTITYTIINPSELFHI-VPSTGVMSIRAGF-----DLDRESI 269

Query: 330 AKYQLLVTATDGGDPPRSATA 350
             YQ++V A D   PP  A A
Sbjct: 270 DAYQVIVQARDDSVPPNVAQA 290



 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 77/256 (30%), Positives = 119/256 (46%), Gaps = 43/256 (16%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I+V D ND +PVF    Y A+V   + +GT V  + ATD D   N     T  L   DT
Sbjct: 92  KIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN----LTFSLARQDT 147

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128
                             ++F ++  +G + ++ A+L R    R T  +K T     VSD
Sbjct: 148 ------------------ELFAVNPLTGVVTVSNAALLR----RDTYTIKLT-----VSD 180

Query: 129 RLSSTATIHVNIIDDN--DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
             + TA   V I  +N   +  QFS K Y+ SV E +SV D+ ++  ++A    +G  S 
Sbjct: 181 G-NHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSV-DSELVT-VRALGYPIG--ST 235

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           I Y II  N    F I   +G +S+     LD E + +Y+++++A+D   P       + 
Sbjct: 236 ITYTII--NPSELFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVH 293

Query: 245 INIRDVNDNAPRFYTS 260
           + + D NDN P F  S
Sbjct: 294 VQVIDRNDNQPVFINS 309



 Score = 55.6 bits (128), Expect = 5e-07
 Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 28/137 (20%)

Query: 23  FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXX 82
           F  + Y ASVREG S  + ++T++A    IG    + YTI       +NP +        
Sbjct: 203 FSRKNYSASVREGVSVDSELVTVRALGYPIGST--ITYTI-------INPSE-------- 245

Query: 83  XXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140
                 +F I   +G +  RA   LDRE +  Y V+V+A D + P +    + A +HV +
Sbjct: 246 ------LFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPN---VAQAAVHVQV 296

Query: 141 IDDNDNYPQFSEKTYTV 157
           ID NDN P F    Y +
Sbjct: 297 IDRNDNQPVFINSPYFI 313


>SB_10746| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 336

 Score =  119 bits (286), Expect = 4e-26
 Identities = 96/316 (30%), Positives = 151/316 (47%), Gaps = 15/316 (4%)

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRL-----HYEITGGNTRGRFSITSQNG--RGLITVA 426
           ++ E++ PG  V  ++ TD  +  RL      Y+I G    G F I +  G  R  I + 
Sbjct: 23  QVKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGP-ADGIFEINAATGVLRTKILLN 81

Query: 427 Q---PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           +   P   + +   +     TD+GG S T   ++ + D N+++P F        + E AP
Sbjct: 82  REKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAP 141

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             +   +  A D+D+G N+   Y +     +   +   ++F  +     +   K LDRET
Sbjct: 142 ERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRET 201

Query: 544 MSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              Y L + A DGG P   S   +V I+++D ND+ P F +  YTA++ E+A  GT + +
Sbjct: 202 RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLR 261

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A D D+G NG I + LD +  E G F +D  +G I TN  LD E  + + L  VA D 
Sbjct: 262 VTAIDQDIGKNGEIMFYLD-ESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQ 320

Query: 663 GTPPQSSTVIVHIKIE 678
           G  P S  V   + I+
Sbjct: 321 G--PDSIPVRAQVTIK 334



 Score =  118 bits (283), Expect = 9e-26
 Identities = 87/268 (32%), Positives = 131/268 (48%), Gaps = 24/268 (8%)

Query: 89  VFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSDRLSSTATIHVNIID 142
           +F I+  +G L T+  L+REK+        + + +K T     VS    +T    V ++D
Sbjct: 64  IFEINAATGVLRTKILLNREKLPPSAQGDIFQIQIKVTTDTGGVS----ATIPTEVRVLD 119

Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202
            ND+ P+F +    + + E  S  +       +A DAD+G NS   Y I+ GN    FS+
Sbjct: 120 INDHSPKFPQDFEELQISE--SAPERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSL 177

Query: 203 D--SLSGDVSLV-----KTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNA 254
                S D+  V     K LD E    Y+LVI A DGG P  RS   ++ I I D ND++
Sbjct: 178 SLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHS 237

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P F    +  SV EN P G  ++RV A D D G N E+ + + +    G       +D  
Sbjct: 238 PEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDESPERG----LFRMDEY 293

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGG 342
           +G ++T+  LD E +++Y+L V A D G
Sbjct: 294 TGEIWTNAVLDYEVKSEYRLTVVAQDQG 321



 Score = 95.9 bits (228), Expect = 4e-19
 Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 16/241 (6%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  ++ VLD NDHSP F     E  + E A   +     +A D DIG N+  EY I    
Sbjct: 111 IPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRGN 170

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            D L                 D+  +      L+    LDRE    Y +++ A D   P+
Sbjct: 171 EDGL-------FSLSLKRFSPDMIYV-----YLVNTKRLDRETRDFYQLVIVAVDGGFPL 218

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               S    +++ I+D ND+ P+FS+  YT SV E+    +   + ++ A D D+G N  
Sbjct: 219 PR--SGRKEVNITILDSNDHSPEFSKDFYTASVPEN--APNGTYLLRVTAIDQDIGKNGE 274

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           I + +     +  F +D  +G++     LDYE    YRL + AQD G  S     Q+ I 
Sbjct: 275 IMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIK 334

Query: 247 I 247
           +
Sbjct: 335 V 335



 Score = 91.5 bits (217), Expect = 9e-18
 Identities = 82/249 (32%), Positives = 110/249 (44%), Gaps = 20/249 (8%)

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           Q+ VT   GG    SAT                F     E++++E  P  +      A D
Sbjct: 97  QIKVTTDTGGV---SATIPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALD 153

Query: 393 ADEDNRL--HYEITGGNTRGRFSITSQN-GRGLITV----AQPLDFKQERRYVLTVSATD 445
           AD  N     Y I  GN  G FS++ +     +I V     + LD +    Y L + A D
Sbjct: 154 ADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVD 213

Query: 446 SG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
            G    RS    V I I D+N+++P F    YTASV E+AP GT +L V+A D D+G N 
Sbjct: 214 GGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNG 273

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           +I + L               F ++  TG I TN +LD E  S Y LTV A+D G  S+ 
Sbjct: 274 EIMFYLDESPERGL-------FRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIP 326

Query: 563 DTTDVEISV 571
               V I V
Sbjct: 327 VRAQVTIKV 335



 Score = 87.0 bits (206), Expect = 2e-16
 Identities = 94/318 (29%), Positives = 148/318 (46%), Gaps = 27/318 (8%)

Query: 590 IMEDALVGTSVSQVGATDADVGLN---GRIHYELD-PKDREEGSFVIDPASGVIRTNKAL 645
           + E+   G  V  V  TD    L    G+I Y++  P D   G F I+ A+GV+RT   L
Sbjct: 24  VKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGPAD---GIFEINAATGVLRTKILL 80

Query: 646 DRESV---ATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
           +RE +   A  D+  + I   T     S+T+   +++ DIND  P F  D     ISE++
Sbjct: 81  NREKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESA 140

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD---LDYE 757
           P  +     RA D D G N++  Y I  G++   FSL  ++ S     V +V+   LD E
Sbjct: 141 PERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRE 200

Query: 758 SPRKKYELVIRAASP--PLWNDVRVEILVT--DVNDNAP-VMKDFQIIFNNYKDCFPVGP 812
           + R  Y+LVI A     PL    R E+ +T  D ND++P   KDF     +  +  P G 
Sbjct: 201 T-RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTA--SVPENAPNGT 257

Query: 813 F-GRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
           +  RV A D D+    ++ + +       L  ++E TG +  +  L+  V     + V  
Sbjct: 258 YLLRVTAIDQDIGKNGEIMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVA 317

Query: 870 TD-GVNEIKAMMQLSVRL 886
            D G + I    Q+++++
Sbjct: 318 QDQGPDSIPVRAQVTIKV 335



 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 10/235 (4%)

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           D G  S +  T+  + + D+ND++P+F     +  +SE+ P        +A DAD G N+
Sbjct: 103 DTGGVSATIPTE--VRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNS 160

Query: 291 ELTYTMTDKDYTGNVDLPIT-IDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDP-PR 346
              Y +   +  G   L +    P   +VY   + +LDRET+  YQL++ A DGG P PR
Sbjct: 161 IQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPR 220

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404
           S                  F    Y   + E+ P GT ++ +TA D D  ++  + + + 
Sbjct: 221 SGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLD 280

Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
               RG F +    G   I     LD++ +  Y LTV A D G  S     Q+ I
Sbjct: 281 ESPERGLFRMDEYTGE--IWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTI 333


>SB_4448| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 245

 Score =  117 bits (281), Expect = 2e-25
 Identities = 66/196 (33%), Positives = 106/196 (54%), Gaps = 8/196 (4%)

Query: 105 LDREKVAR-YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           LDRE     +T+ V ATDQ +   ++LS+T    + + D ND+ P F+++ +  +V ED 
Sbjct: 16  LDRETSPNSFTITVLATDQGA---NKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSED- 71

Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
            V    V+  + ATD D G N+ + + +  GN    F +D   G V +   L+Y   +SY
Sbjct: 72  -VRPGYVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVFDILNYTLRKSY 130

Query: 224 RLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
            L +   D G P  S ++   +LI I D NDNAP F  + + ++V+E++ +G  +V V A
Sbjct: 131 NLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTA 190

Query: 282 YDADEGVNAELTYTMT 297
            D D G NA+  + +T
Sbjct: 191 VDYDSGDNAKFVFDIT 206



 Score =  113 bits (273), Expect = 1e-24
 Identities = 69/188 (36%), Positives = 99/188 (52%), Gaps = 11/188 (5%)

Query: 437 YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           + +TV ATD G    S T +  I +TDAN++APVF    +  +V ED   G  V  VSAT
Sbjct: 25  FTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSAT 84

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D+D G NA++ + ++    NE  A     F ++P  G +    +L+      Y LTVT  
Sbjct: 85  DTDTGPNAELEFVVTH--GNEPAA-----FYVDPSKGTVHVFDILNYTLRKSYNLTVTVS 137

Query: 555 DGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           D G+P LSD +   V I++ D NDN P+F    Y   + ED  VG+ V  V A D D G 
Sbjct: 138 DRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGD 197

Query: 613 NGRIHYEL 620
           N +  +++
Sbjct: 198 NAKFVFDI 205



 Score =  110 bits (265), Expect = 1e-23
 Identities = 74/218 (33%), Positives = 105/218 (48%), Gaps = 8/218 (3%)

Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
           S+ + + A D G+   S T    I + D ND+AP F   +F+ +VSE+V  GY +  V A
Sbjct: 24  SFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSA 83

Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
            D D G NAEL + +T     GN      +DP  G V+    L+   +  Y L VT +D 
Sbjct: 84  TDTDTGPNAELEFVVTH----GNEPAAFYVDPSKGTVHVFDILNYTLRKSYNLTVTVSDR 139

Query: 342 GDPPRS--ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN- 397
           G P  S  + A               F+P QY   +AED   G+PVV +TA D D  DN 
Sbjct: 140 GMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNA 199

Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
           +  ++ITGGN    F    +N   L+ V+  L +  +R
Sbjct: 200 KFVFDITGGNPNDLFESRPRNRIILVWVSCALGYPLDR 237



 Score =  108 bits (259), Expect = 7e-23
 Identities = 64/207 (30%), Positives = 102/207 (49%), Gaps = 4/207 (1%)

Query: 537 KLLDRETM-SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           ++LDRET  + + +TV A D G   LS T    I V D ND+ PVF ++++   + ED  
Sbjct: 14  EILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVR 73

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
            G  V+ V ATD D G N  + + +     E  +F +DP+ G +     L+     +++L
Sbjct: 74  PGYVVTSVSATDTDTGPNAELEFVV-THGNEPAAFYVDPSKGTVHVFDILNYTLRKSYNL 132

Query: 656 KAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
                D G P    +S   V I I D ND+ P+F  +     ++E+  +G+ +  + A D
Sbjct: 133 TVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVD 192

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETR 740
            D G NA   + I GG+ ++ F    R
Sbjct: 193 YDSGDNAKFVFDITGGNPNDLFESRPR 219



 Score = 90.2 bits (214), Expect = 2e-17
 Identities = 68/227 (29%), Positives = 103/227 (45%), Gaps = 10/227 (4%)

Query: 324 LDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           LDRET    + + V ATD G    S T                F    +   ++ED  PG
Sbjct: 16  LDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPG 75

Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             V +++ATD D   +  L + +T GN    F +     +G + V   L++   + Y LT
Sbjct: 76  YVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPS--KGTVHVFDILNYTLRKSYNLT 133

Query: 441 VSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           V+ +D G      +  A V I ITDAN+ AP+F    Y  +V ED  +G+ V+VV+A D 
Sbjct: 134 VTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDY 193

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           D G NA+  + ++    N+      +  +I     +      LDRET
Sbjct: 194 DSGDNAKFVFDITGGNPNDLFESRPRNRIILVWV-SCALGYPLDRET 239



 Score = 77.0 bits (181), Expect = 2e-13
 Identities = 61/186 (32%), Positives = 87/186 (46%), Gaps = 24/186 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D NDH+PVF  + +  +V E    G  V ++ ATD D G NAE+E+ +      T 
Sbjct: 47  IYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVV------TH 100

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV-SDR 129
             E A              F +D   G +     L+      Y + V  +D+  PV SD 
Sbjct: 101 GNEPA-------------AFYVDPSKGTVHVFDILNYTLRKSYNLTVTVSDRGMPVLSD- 146

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +S A + + I D NDN P F    Y  +V ED++V  +PV+  + A D D G N+   +
Sbjct: 147 -NSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAV-GSPVVV-VTAVDYDSGDNAKFVF 203

Query: 190 AIIGGN 195
            I GGN
Sbjct: 204 DITGGN 209



 Score = 72.1 bits (169), Expect = 6e-12
 Identities = 58/201 (28%), Positives = 92/201 (45%), Gaps = 12/201 (5%)

Query: 645 LDRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
           LDRE S  +  +  +A D G    S+T +  I + D ND  PVF        +SE+   G
Sbjct: 16  LDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPG 75

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             +  + A D D GPNA + + +  G++  +F ++  +G+     V + D+   + RK Y
Sbjct: 76  YVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGT-----VHVFDILNYTLRKSY 130

Query: 764 ELVIRAA--SPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
            L +  +    P+ +D     V I +TD NDNAP+    Q      +D     P   V A
Sbjct: 131 NLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTA 190

Query: 819 YDADVTDKLQYRI-LSGNNAN 838
            D D  D  ++   ++G N N
Sbjct: 191 VDYDSGDNAKFVFDITGGNPN 211



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANL 839
           I VTD ND+APV           +D  P      V A D D     +L++ +  GN    
Sbjct: 47  IYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTHGNEPAA 106

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             ++ + G++ +   LN  + K   + V+V+D
Sbjct: 107 FYVDPSKGTVHVFDILNYTLRKSYNLTVTVSD 138


>SB_34938| Best HMM Match : Cadherin (HMM E-Value=1e-25)
          Length = 150

 Score =  109 bits (263), Expect = 2e-23
 Identities = 62/154 (40%), Positives = 86/154 (55%), Gaps = 7/154 (4%)

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
           S NG  L   + PLD +   +++L +S T+ G       V +N+ D N+  P+F++  + 
Sbjct: 3   SINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFN 62

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            SV E   +GT  L VSATD D G N+ +TYS+       A  + +  F IN +TGAI+ 
Sbjct: 63  VSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISV 115

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
            K LDRET   Y LTV A+DGG P L+ TT V I
Sbjct: 116 AKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAI 149



 Score = 91.5 bits (217), Expect = 9e-18
 Identities = 54/157 (34%), Positives = 85/157 (54%), Gaps = 8/157 (5%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F I+G +   +    LDRE  A++ + +  T+  +     +     + VN++D ND  P
Sbjct: 1   MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 54

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G 
Sbjct: 55  LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 112

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           +S+ K LD E    Y L + AQDGG P  ++TT + I
Sbjct: 113 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAI 149



 Score = 90.2 bits (214), Expect = 2e-17
 Identities = 49/138 (35%), Positives = 76/138 (55%), Gaps = 3/138 (2%)

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRET + ++L ++  +GG  ++     V ++V+D+ND  P+F+   +  ++ E   +GT
Sbjct: 16  LDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 73

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
               V ATD D G N  + Y +     EEG F I+  +G I   K LDRE+   + L  +
Sbjct: 74  VFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVM 132

Query: 659 AIDGGTPPQSSTVIVHIK 676
           A DGG PP +ST  V I+
Sbjct: 133 AQDGGEPPLNSTTAVAIQ 150



 Score = 81.4 bits (192), Expect = 9e-15
 Identities = 47/135 (34%), Positives = 74/135 (54%), Gaps = 6/135 (4%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
           LD E    + L I   +GG+       ++ +N+ D+ND  P F +  F  SV+E   +G 
Sbjct: 16  LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 73

Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
             + V A D D G N+ LTY++      GN +   +I+ ++G +  + QLDRET+ +Y L
Sbjct: 74  VFLTVSATDGDAGANSALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRETRDQYTL 129

Query: 335 LVTATDGGDPPRSAT 349
            V A DGG+PP ++T
Sbjct: 130 TVMAQDGGEPPLNST 144



 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 46/141 (32%), Positives = 68/141 (48%), Gaps = 10/141 (7%)

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           LDRE+ A H L     +GGT      V V + + DIND  P+F+S      ++E   +GT
Sbjct: 16  LDRETAAQHILDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 73

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
               + A D D G N+ + YSI  G++   FS+  + G+    +     LD E+ R +Y 
Sbjct: 74  VFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYT 128

Query: 765 LVIRA---ASPPLWNDVRVEI 782
           L + A     PPL +   V I
Sbjct: 129 LTVMAQDGGEPPLNSTTAVAI 149



 Score = 62.5 bits (145), Expect = 5e-09
 Identities = 46/129 (35%), Positives = 62/129 (48%), Gaps = 6/129 (4%)

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           S  LDRET A++ L ++ T+GG        T              F    + V + E E 
Sbjct: 13  STPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPL--FQSPSFNVSVNEIER 70

Query: 381 PGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
            GT  +T++ATD D   ++ L Y I  GN  G FSI   N  G I+VA+ LD +   +Y 
Sbjct: 71  LGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSI--NNKTGAISVAKQLDRETRDQYT 128

Query: 439 LTVSATDSG 447
           LTV A D G
Sbjct: 129 LTVMAQDGG 137



 Score = 57.6 bits (133), Expect = 1e-07
 Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 19/124 (15%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I        
Sbjct: 44  VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 95

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +  F I+ ++GA+     LDRE   +YT+ V A D   P  +  
Sbjct: 96  -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 144

Query: 131 SSTA 134
           ++ A
Sbjct: 145 TAVA 148



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 778 VRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833
           V+V + V D+ND  P+ +   F +  N  +    V  F  V A D D      L Y I +
Sbjct: 40  VKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAA 97

Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           GN      +N  TG+++++ QL+       T+ V   DG
Sbjct: 98  GNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 136


>SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0)
          Length = 645

 Score =  106 bits (255), Expect = 2e-22
 Identities = 128/464 (27%), Positives = 190/464 (40%), Gaps = 67/464 (14%)

Query: 1049 GFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQ---GCSIDAAYTTAVCEL 1105
            G+ G  CE +  + S        +C  G +CV R + G  C    G   D     +V E 
Sbjct: 198  GYKGRTCEGVGERCS------PGVCNKG-RCVNRGDTGFDCLCPVGFKGDRCQEGSVIE- 249

Query: 1106 RARSFPVSSFLTFPGLKRRH-RIHLKLKF-ATQTTSGLLLYNGR--YNERHDFLALELVS 1161
                F V SF++FPG++    +I L ++F A   + GLLLYNG+  +  R DF+++ +V 
Sbjct: 250  -TPQFDVKSFMSFPGIQGALLKIKLSMRFMANDASDGLLLYNGQRLHPNRGDFVSIAIV- 307

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSL 1221
                   G  + F + LG G++ I  + N+  G WHTV  E + R  ++ILD    V S 
Sbjct: 308  -------GGNVEFRYDLGYGRAVIRSKKNITVGQWHTVVAERYRRDGSLILDSEPAVKSQ 360

Query: 1222 AGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDF 1281
            A     GL  A   +   VL     I T+            ++G            N+ F
Sbjct: 361  APCCSVGLNLALPLYVGGVLNFE-TIDTD------------KVG-----------VNRGF 396

Query: 1282 VGCISDFYIDHKFIDL-NSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT-YICDC 1339
             GCISD  +D   IDL NSYV   G +  C E    C   PC N   C     T Y+C C
Sbjct: 397  KGCISDVAVDDNPIDLINSYVKHRG-IEQCTECLLPCQIEPCVNNGTCIPRGQTGYMCAC 455

Query: 1340 KEGHTGKDCA-DSTGP-PWRFGGDGMLSFNPLLR----PIQLPWLNALSIRTRQRDAFVM 1393
             +G TGK+C     GP   R   +G L F P  R    P+        S+   +     +
Sbjct: 456  GDGFTGKNCEFPLVGPGKNRTCMNGGLPFPPSGRVCDCPVGYAGKRCESVVQLEDSMSFL 515

Query: 1394 S---IQLKSGLLHYSYN---GETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVL 1447
                +Q    ++  +Y    G  +      + DG WH +++     D ++ +D     ++
Sbjct: 516  GDGYVQYPGSVMRRNYELGAGPAVLRSRRRVDDGQWHFVKVFRRSQDGALQIDDD--EIV 573

Query: 1448 MPMLANKIQG-QYIGKILIGGLDTTAGL-LASDVGFFEGCIQDV 1489
                 N  +     G I IGG D    L        F GC+  +
Sbjct: 574  NGTSKNGARSLNTPGPIFIGGGDDVETLTYGKYAASFRGCVSGI 617



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 79/353 (22%), Positives = 124/353 (35%), Gaps = 38/353 (10%)

Query: 1256 LDLTGPLQIGGLPNIPS--SFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEK 1313
            L+L   + +GG+ N      F   N+ F+GCIS   +D      N+ +        C   
Sbjct: 154  LNLNQNMFLGGVANYSKIDRFSGFNRGFIGCISYIKVD------NNTIRPGYKGRTCEGV 207

Query: 1314 RSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDCAD-STGPPWRFGGDGMLSFNPL-- 1369
              RCS   C N   C +  DT + C C  G  G  C + S     +F     +SF  +  
Sbjct: 208  GERCSPGVC-NKGRCVNRGDTGFDCLCPVGFKGDRCQEGSVIETPQFDVKSFMSFPGIQG 266

Query: 1370 -LRPIQLPW-------LNALSIRTRQR----DAFVMSIQLKSGLLHYSYN---GETMYLP 1414
             L  I+L          + L +   QR        +SI +  G + + Y+   G  +   
Sbjct: 267  ALLKIKLSMRFMANDASDGLLLYNGQRLHPNRGDFVSIAIVGGNVEFRYDLGYGRAVIRS 326

Query: 1415 MATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGL 1474
               ++ G WH +  +    D S+ +D     V        +       + +GG+     +
Sbjct: 327  KKNITVGQWHTVVAERYRRDGSLILD-SEPAVKSQAPCCSVGLNLALPLYVGGVLNFETI 385

Query: 1475 LASDVGF---FEGCIQDVRI-GTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVT 1530
                VG    F+GCI DV +      L+N       +    +    C +  C     C+ 
Sbjct: 386  DTDKVGVNRGFKGCISDVAVDDNPIDLINSYVKHRGIEQCTECLLPCQIEPCVNNGTCIP 445

Query: 1531 SWDSS-TCTCEAGRVGPQCVSACELGPCGAARCVPDQ---TPKGYSCACEPGY 1579
               +   C C  G  G  C     +GP     C+       P G  C C  GY
Sbjct: 446  RGQTGYMCACGDGFTGKNCEFPL-VGPGKNRTCMNGGLPFPPSGRVCDCPVGY 497



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 1547 QCVSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
            +C+  C++ PC     C+P +   GY CAC  G+T
Sbjct: 427  ECLLPCQIEPCVNNGTCIP-RGQTGYMCACGDGFT 460



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%)

Query: 1037 YPVTSFTCQCPEGFTGVNCETIL-TKASCEVDGDGSICRSGS 1077
            +P +   C CP G+ G  CE+++  + S    GDG +   GS
Sbjct: 484  FPPSGRVCDCPVGYAGKRCESVVQLEDSMSFLGDGYVQYPGS 525


>SB_40244| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 566

 Score =  105 bits (253), Expect = 4e-22
 Identities = 127/502 (25%), Positives = 210/502 (41%), Gaps = 65/502 (12%)

Query: 129 RLSSTATIHVNII--DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
           R   TA++ V++     N N P+   +   VSV E+ S  D  ++A I ATDAD  ++  
Sbjct: 37  RAQHTASLRVSVFVFPVNQNAPKIYPRHMVVSVYENASKGD--MVASINATDAD--SHDQ 92

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           + Y ++ G    +F ++S +G +S+V+ LD E    Y+L +  QD  S   S+  ++ I 
Sbjct: 93  LLYTLLAGGDG-RFQLNSSTGVLSVVEQLDRESTAQYKLFVLVQDRQSLPYSDYGEVDIT 151

Query: 247 IRDVNDNAPRFYTSLFQES------VSENVPIG--------YSIVRVQAYDADEGVNAEL 292
           + DVNDN P+      QES      ++EN            Y +V   A D     + + 
Sbjct: 152 VIDVNDNQPQLSKDREQESSYNLTIIAENTLARPRLRSKHMYHVVVDDANDFPPSFSRQT 211

Query: 293 TYT-MTDKDYTG------NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--- 342
            Y  +T+    G      N   P T   +S  VY     ++ +   Y+ L+    G    
Sbjct: 212 YYAHVTEGTPVGTLVINLNASDPDTDSGKSHLVYRIIH-EKSSLESYRFLMDPESGDITT 270

Query: 343 ----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398
               D  R A+                 M  Q     +E    G  +  + A D DE + 
Sbjct: 271 QSEIDRERIASYNVSVKFILMEQLRFVRMKVQSGFSASESSAIGDVIARVHAEDKDEGSN 330

Query: 399 --LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--------- 447
             + Y+IT GN  G F +    G   +T+A+PLDF+ +  Y LTV + +           
Sbjct: 331 AVITYQITLGNEDGNFLLHPMTGD--LTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARAR 388

Query: 448 -----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
                 +SD A+V + + DAN+  PVF    +          G  +LVV A D D   + 
Sbjct: 389 RQVLTSKSDEAIVTVKVNDANDNQPVFIKDVFVGGFVYKDYTGGAILVVKAIDKDSFASG 448

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMSGYLLTVTA--RDGGV 558
            + Y  +++  + A+       ++NP+TG ++ N   +   E    Y L V A   DG  
Sbjct: 449 PVIYRETNQSPSGAL-------LLNPRTGHVSLNLASIHVNEATKRYTLEVMASDNDGKF 501

Query: 559 PSLSDTTDVEISVVDVNDNEPV 580
           P  + T    + ++   +++ V
Sbjct: 502 PYNNSTKTANVVILQFTEDDNV 523



 Score =  104 bits (249), Expect = 1e-21
 Identities = 108/357 (30%), Positives = 161/357 (45%), Gaps = 50/357 (14%)

Query: 540 DRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           DRE  S Y LT+ A +    P L       + V D ND  P F +Q Y A++ E   VGT
Sbjct: 165 DREQESSYNLTIIAENTLARPRLRSKHMYHVVVDDANDFPPSFSRQTYYAHVTEGTPVGT 224

Query: 599 SVSQVGATDADVGLNGRIH--YEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
            V  + A+D D   +G+ H  Y +  +    E   F++DP SG I T   +DRE +A+++
Sbjct: 225 LVINLNASDPDTD-SGKSHLVYRIIHEKSSLESYRFLMDPESGDITTQSEIDRERIASYN 283

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           +    I            V +K++               F  SE+S IG  I  + A D 
Sbjct: 284 VSVKFI-----LMEQLRFVRMKVQS-------------GFSASESSAIGDVIARVHAEDK 325

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----A 770
           DEG NAV+ Y I  G++  +F L    G    +L     LD+E  +  Y L +R+     
Sbjct: 326 DEGSNAVITYQITLGNEDGNFLLHPMTG----DLTIAKPLDFEY-KSVYTLTVRSFNIDP 380

Query: 771 SPPL-----------WNDVRVEILVTDVNDNAPV-MKDFQIIFNNYKDCFPVGPFGRVPA 818
           S PL            ++  V + V D NDN PV +KD  +    YKD +  G    V A
Sbjct: 381 SSPLARARRQVLTSKSDEAIVTVKVNDANDNQPVFIKDVFVGGFVYKD-YTGGAILVVKA 439

Query: 819 YDAD--VTDKLQYRILSGNNANLILLNETTGSMTLS-PQLNTN-VPKLATMEVSVTD 871
            D D   +  + YR  + + +  +LLN  TG ++L+   ++ N   K  T+EV  +D
Sbjct: 440 IDKDSFASGPVIYRETNQSPSGALLLNPRTGHVSLNLASIHVNEATKRYTLEVMASD 496



 Score = 89.8 bits (213), Expect = 3e-17
 Identities = 94/353 (26%), Positives = 153/353 (43%), Gaps = 58/353 (16%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND  P F  Q Y A V EG   GT V+ L A+D D        + +  +  +  + E 
Sbjct: 199 DANDFPPSFSRQTYYAHVTEGTPVGTLVINLNASDPDTDSGKS--HLVYRIIHEKSSLES 256

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                          F +D  SG + T++ +DRE++A Y V VK                
Sbjct: 257 YR-------------FLMDPESGDITTQSEIDRERIASYNVSVKF--------------- 288

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
                I+ +   + +   ++   S  E  ++ D  VIA++ A D D G+N+ I Y I  G
Sbjct: 289 -----ILMEQLRFVRMKVQS-GFSASESSAIGD--VIARVHAEDKDEGSNAVITYQITLG 340

Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA--QDGGSP----------SRSNTTQ 242
           N    F +  ++GD+++ K LD+E    Y L +R+   D  SP          S+S+   
Sbjct: 341 NEDGNFLLHPMTGDLTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARARRQVLTSKSDEAI 400

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           + + + D NDN P F   +F          G +I+ V+A D D   +  + Y  T++  +
Sbjct: 401 VTVKVNDANDNQPVFIKDVFVGGFVYKDYTGGAILVVKAIDKDSFASGPVIYRETNQSPS 460

Query: 303 GNVDLPITIDPRSGWVYTS-GQLD-RETQAKYQLLVTAT--DGGDPPRSATAT 351
           G     + ++PR+G V  +   +   E   +Y L V A+  DG  P  ++T T
Sbjct: 461 G----ALLLNPRTGHVSLNLASIHVNEATKRYTLEVMASDNDGKFPYNNSTKT 509



 Score = 83.8 bits (198), Expect = 2e-15
 Identities = 110/401 (27%), Positives = 169/401 (42%), Gaps = 53/401 (13%)

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
           DY G VD+ + ID        S   DRE ++ Y L + A +    PR  +          
Sbjct: 144 DY-GEVDITV-IDVNDNQPQLSK--DREQESSYNLTIIAENTLARPRLRSKHMYHVVVDD 199

Query: 360 XXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---RLHYEITGGNTR---GRF 412
                  F    Y   + E  P GT V+ L A+D D D+    L Y I    +     RF
Sbjct: 200 ANDFPPSFSRQTYYAHVTEGTPVGTLVINLNASDPDTDSGKSHLVYRIIHEKSSLESYRF 259

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472
            +  ++G   IT    +D  +ER     VS            V+  + +   +  +   +
Sbjct: 260 LMDPESGD--ITTQSEID--RERIASYNVS------------VKFILMEQLRFVRMKVQS 303

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            ++AS  E + IG  +  V A D D G NA ITY ++  + NE     D  F+++P TG 
Sbjct: 304 GFSAS--ESSAIGDVIARVHAEDKDEGSNAVITYQIT--LGNE-----DGNFLLHPMTGD 354

Query: 533 ITTNKLLDRETMSGYLLTVT------------ARDGGVPSLSDTTDVEISVVDVNDNEPV 580
           +T  K LD E  S Y LTV             AR   + S SD   V + V D NDN+PV
Sbjct: 355 LTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARARRQVLTSKSDEAIVTVKVNDANDNQPV 414

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
           F + ++    +     G ++  V A D D   +G + Y  +      G+ +++P +G + 
Sbjct: 415 FIKDVFVGGFVYKDYTGGAILVVKAIDKDSFASGPVIYR-ETNQSPSGALLLNPRTGHVS 473

Query: 641 TNKALDRESVAT--HDLKAVAI--DGGTPPQSSTVIVHIKI 677
            N A    + AT  + L+ +A   DG  P  +ST   ++ I
Sbjct: 474 LNLASIHVNEATKRYTLEVMASDNDGKFPYNNSTKTANVVI 514



 Score = 72.9 bits (171), Expect = 3e-12
 Identities = 91/364 (25%), Positives = 147/364 (40%), Gaps = 44/364 (12%)

Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           S DRE+ + Y + + A +  +    RL S    HV + D ND  P FS +TY   V E  
Sbjct: 163 SKDREQESSYNLTIIAENTLA--RPRLRSKHMYHVVVDDANDFPPSFSRQTYYAHVTEGT 220

Query: 164 SVTDNPVIAKIKATDADV-GANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQ 219
            V    ++  + A+D D     S + Y II   + ++   F +D  SGD++    +D E+
Sbjct: 221 PV--GTLVINLNASDPDTDSGKSHLVYRIIHEKSSLESYRFLMDPESGDITTQSEIDRER 278

Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
           + SY + ++              L+  +R V       +      S SE+  IG  I RV
Sbjct: 279 IASYNVSVK------------FILMEQLRFVRMKVQSGF------SASESSAIGDVIARV 320

Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA- 338
            A D DEG NA +TY +T     GN D    + P +G +  +  LD E ++ Y L V + 
Sbjct: 321 HAEDKDEGSNAVITYQIT----LGNEDGNFLLHPMTGDLTIAKPLDFEYKSVYTLTVRSF 376

Query: 339 -TDGGDP----------PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
             D   P           +S  A               F+   +       +  G  ++ 
Sbjct: 377 NIDPSSPLARARRQVLTSKSDEAIVTVKVNDANDNQPVFIKDVFVGGFVYKDYTGGAILV 436

Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
           + A D D      + Y  T  +  G   +  + G   + +A     +  +RY L V A+D
Sbjct: 437 VKAIDKDSFASGPVIYRETNQSPSGALLLNPRTGHVSLNLASIHVNEATKRYTLEVMASD 496

Query: 446 SGGR 449
           + G+
Sbjct: 497 NDGK 500



 Score = 69.3 bits (162), Expect = 4e-11
 Identities = 48/161 (29%), Positives = 80/161 (49%), Gaps = 12/161 (7%)

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASV 478
           G + + +P      +     V+  D G    TA +++++     N  AP         SV
Sbjct: 10  GTLALVKPAKDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPKIYPRHMVVSV 69

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
           +E+A  G  V  ++ATD+D   + Q+ Y+L        +A  D +F +N  TG ++  + 
Sbjct: 70  YENASKGDMVASINATDADS--HDQLLYTL--------LAGGDGRFQLNSSTGVLSVVEQ 119

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
           LDRE+ + Y L V  +D      SD  +V+I+V+DVNDN+P
Sbjct: 120 LDRESTAQYKLFVLVQDRQSLPYSDYGEVDITVIDVNDNQP 160



 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 45/167 (26%), Positives = 74/167 (44%), Gaps = 4/167 (2%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F +   +G +   K             VT +D G    + +  V + V  VN N P    
Sbjct: 3   FAVEAMSGTLALVKPAKDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPKIYP 62

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
           +    ++ E+A  G  V+ + ATDAD   + ++ Y L      +G F ++ ++GV+   +
Sbjct: 63  RHMVVSVYENASKGDMVASINATDADS--HDQLLYTLLAGG--DGRFQLNSSTGVLSVVE 118

Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            LDRES A + L  +  D  + P S    V I + D+ND+ P    D
Sbjct: 119 QLDRESTAQYKLFVLVQDRQSLPYSDYGEVDITVIDVNDNQPQLSKD 165



 Score = 59.3 bits (137), Expect = 4e-08
 Identities = 41/148 (27%), Positives = 71/148 (47%), Gaps = 7/148 (4%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F+++++SG ++LVK       ++   V+  +D G    + + ++ + +  VN NAP+ Y 
Sbjct: 3   FAVEAMSGTLALVKPAKDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPKIYP 62

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
                SV EN   G  +  + A DAD   + +L YT+         D    ++  +G + 
Sbjct: 63  RHMVVSVYENASKGDMVASINATDADS--HDQLLYTL-----LAGGDGRFQLNSSTGVLS 115

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRS 347
              QLDRE+ A+Y+L V   D    P S
Sbjct: 116 VVEQLDRESTAQYKLFVLVQDRQSLPYS 143



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 9/166 (5%)

Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAI--DGGTPPQSSTVIVHIKIEDINDSPPV 686
           SF ++  SG +   K    + V   ++  V    D G    ++++ V + +  +N + P 
Sbjct: 2   SFAVEAMSGTLALVKPA--KDVVNQNISFVVTCKDHGRAQHTASLRVSVFVFPVNQNAPK 59

Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
                +   + EN+  G  +  I A D D     +  Y++  G D   F L +  G    
Sbjct: 60  IYPRHMVVSVYENASKGDMVASINATDADSHDQLL--YTLLAGGDGR-FQLNSSTGV--L 114

Query: 747 ELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
            +V  +D +  +  K + LV    S P  +   V+I V DVNDN P
Sbjct: 115 SVVEQLDRESTAQYKLFVLVQDRQSLPYSDYGEVDITVIDVNDNQP 160



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 1/79 (1%)

Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837
           +RV + V  VN NAP +    ++ + Y++         + A DAD  D+L Y +L+G + 
Sbjct: 44  LRVSVFVFPVNQNAPKIYPRHMVVSVYENASKGDMVASINATDADSHDQLLYTLLAGGDG 103

Query: 838 NLILLNETTGSMTLSPQLN 856
               LN +TG +++  QL+
Sbjct: 104 R-FQLNSSTGVLSVVEQLD 121



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 63/253 (24%), Positives = 101/253 (39%), Gaps = 37/253 (14%)

Query: 31  SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVF 90
           S  E ++ G  +  + A D+D G NA + Y I      TL  ED               F
Sbjct: 306 SASESSAIGDVIARVHAEDKDEGSNAVITYQI------TLGNEDGN-------------F 346

Query: 91  RIDGRSGALLTRASLDREKVARYTVLVKA--TDQASP-------VSDRLSSTATIHVNII 141
            +   +G L     LD E  + YT+ V++   D +SP       V    S  A + V + 
Sbjct: 347 LLHPMTGDLTIAKPLDFEYKSVYTLTVRSFNIDPSSPLARARRQVLTSKSDEAIVTVKVN 406

Query: 142 DDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200
           D NDN P F +  +    V +D +      I  +KA D D  A+  + Y     +     
Sbjct: 407 DANDNQPVFIKDVFVGGFVYKDYT---GGAILVVKAIDKDSFASGPVIYRETNQSPSGAL 463

Query: 201 SIDSLSGDVSLVKTLDY--EQVRSYRLVIRA--QDGGSPSRSNT-TQLLINIRDVNDNAP 255
            ++  +G VSL     +  E  + Y L + A   DG  P  ++T T  ++ ++   D+  
Sbjct: 464 LLNPRTGHVSLNLASIHVNEATKRYTLEVMASDNDGKFPYNNSTKTANVVILQFTEDDNV 523

Query: 256 RFYTSLFQESVSE 268
           R    +  E + E
Sbjct: 524 RVIAGVPPEFIME 536


>SB_16935| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 2204

 Score =  102 bits (244), Expect = 5e-21
 Identities = 146/584 (25%), Positives = 249/584 (42%), Gaps = 70/584 (11%)

Query: 164 SVTDNPVIAKI--KATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221
           SV +N  +  +  K T  DV +  +  Y ++  + +  F +D+  G + +V+ +D+E   
Sbjct: 193 SVPENSPLGSVVGKLTTLDVDSRQSHSYTMVD-SAEGTFGVDNSLGVLVVVREMDFETHP 251

Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
            + + + + D G+P  S+     I++ DVN+  P     L    V EN  +  +I  + +
Sbjct: 252 QFFIQVMSTDSGTPPLSHVQNFTIDVMDVNE--PPTPPVLAPPVVYENASVHSTIGLLSS 309

Query: 282 YDADEGVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
           +DAD   N  LTYT +TD   T  V+        S  V  S  L  ETQ++Y + V   D
Sbjct: 310 HDADADTN--LTYTLLTDARGTFRVE-------ESRLVLNS-PLSYETQSRYTITVQVRD 359

Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP------GTPVVTLTATDAD 394
            G+P   A+                 +     ++   D+P       GT V TLTA D D
Sbjct: 360 NGNPILVASQAINVTVFDCNDPPTGVIFNGGSLDEYSDDPDVNGTRNGTHVGTLTAIDED 419

Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
             +   +EI    T+G       N   ++  A+ LDF+    + L +  TD    S T+ 
Sbjct: 420 AKDTHVFEIL---TQGS-PFRIHNSTVIVGNARRLDFESRNTWTLLIRVTDQVAASVTSS 475

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           ++I ++D N   P    +  + S  E+AP+GT +  +S  D D     +  +SL +  SN
Sbjct: 476 IRIFLSDINE--PPTMISLSSDSFSENAPVGTLIGSLSTQDPDA--QDRHRFSLETSSSN 531

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVD 573
            +V+ +    ++         NK++D ET+   L + V  RD G  + +   ++ ++  +
Sbjct: 532 -SVSINGSNLIV---------NKVVDFETVLNPLSIQVKVRDSGNLTRNQVFNITVTNSN 581

Query: 574 VNDNEPVFKQQL-----YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
                     QL      T  + E+ L G  V+ +   D D G       ++   D    
Sbjct: 582 EAPTSIELTSQLSCSPGVTLCVPENKLAGYPVAYINVKDPDDG-------DVTTCDVMTD 634

Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAI----DGGTPPQSSTVIVHIKIEDINDSP 684
            F       +I T    + E++ +  + +V I     GG   Q+     +I I D ND+P
Sbjct: 635 EFFGIRDKELIVTGNT-NYEALTSDHVVSVGIFCRDKGGLSAQAD---YNISILDANDAP 690

Query: 685 -PVFESDCLTFYI-SENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             VF    L+ YI S+++P+G+ +G     D D       HY I
Sbjct: 691 TQVF----LSHYIASDSAPVGSLVGRFTVEDEDASD---THYCI 727



 Score = 83.4 bits (197), Expect = 2e-15
 Identities = 107/481 (22%), Positives = 190/481 (39%), Gaps = 45/481 (9%)

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D   N P     +  +SV EN P+G  + ++   D D       +YTM D     + +  
Sbjct: 177 DPGSNRPPSAILISSDSVPENSPLGSVVGKLTTLDVDS--RQSHSYTMVD-----SAEGT 229

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +D   G +    ++D ET  ++ + V +TD G PP S                    P
Sbjct: 230 FGVDNSLGVLVVVREMDFETHPQFFIQVMSTDSGTPPLSHVQNFTIDVMDVNEPPT--PP 287

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
                 + E+    + +  L++ DAD D  L Y +   + RG F +        + +  P
Sbjct: 288 VLAPPVVYENASVHSTIGLLSSHDADADTNLTYTLL-TDARGTFRVEESR----LVLNSP 342

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTT 487
           L ++ + RY +TV   D+G     A   IN+T       VF+ N P T  +F    +   
Sbjct: 343 LSYETQSRYTITVQVRDNGNPILVASQAINVT-------VFDCNDPPTGVIFNGGSLDEY 395

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAH---HDQQFVINPQTGAITTNKLLDRETM 544
                   +  G +     ++  +  +  V         F I+  T  +   + LD E+ 
Sbjct: 396 SDDPDVNGTRNGTHVGTLTAIDEDAKDTHVFEILTQGSPFRIHNSTVIVGNARRLDFESR 455

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
           + + L +   D    S+  T+ + I + D+  NEP     L + +  E+A VGT +  + 
Sbjct: 456 NTWTLLIRVTDQVAASV--TSSIRIFLSDI--NEPPTMISLSSDSFSENAPVGTLIGSLS 511

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH-DLKAVAIDGG 663
             D D     R  + L+       S  I+ ++ ++  NK +D E+V     ++    D G
Sbjct: 512 TQDPDA--QDRHRFSLETS--SSNSVSINGSNLIV--NKVVDFETVLNPLSIQVKVRDSG 565

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFE-------SDCLTFYISENSPIGTTIGEIRAHDPDE 716
              ++   + +I + + N++P   E       S  +T  + EN   G  +  I   DPD+
Sbjct: 566 NLTRNQ--VFNITVTNSNEAPTSIELTSQLSCSPGVTLCVPENKLAGYPVAYINVKDPDD 623

Query: 717 G 717
           G
Sbjct: 624 G 624



 Score = 82.6 bits (195), Expect = 4e-15
 Identities = 159/664 (23%), Positives = 253/664 (38%), Gaps = 54/664 (8%)

Query: 147  YPQ-FSEKTYTVSVDEDISVT-DNPVIAKIKATDADVGANSAIRY-----AIIGGNTQMQ 199
            +PQ F  +   +++   I++T D+  I++ KA  + VG   A+ Y      +   +    
Sbjct: 770  FPQLFFIEVQNLNMSAQINITIDSSEISENKAPGSVVGRIHALSYDPTETLVFDLDDDCN 829

Query: 200  FSIDSLSGDVS----LVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
             +    SG+ +    LV T  LDYE    Y +V+R +  G+  R++  +  I++ DV + 
Sbjct: 830  GTFALTSGNTANTRMLVTTRPLDYETRPQYTVVVRVR--GNAERTSFREFTISVLDVTE- 886

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             P  Y  L   SV EN    +++V +      E     L +T  D D      L  T   
Sbjct: 887  FPDDYLVLHHSSVVENT--AHALVGIVMLR--EPQMRHLAFTAID-DPDDAFMLQPTSFS 941

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             +  + T+  LD E    + +     D      S   T                      
Sbjct: 942  HTCKLLTARPLDYEKAQNHNITFNIRDTPYSQISVNQTFIIAVINVNEPPSAI--NLTNK 999

Query: 374  ELAEDEPPGTPVVTLTATDADEDNRLHYEITG--GNTRGRFSITSQNGRGLITVAQP--L 429
             + E+ P GT +  L   D DE       +     +  GRF ++       + VA P  L
Sbjct: 1000 NIVENSPRGTVIGRLIVEDPDEPFLPQSFVCNLRNDAYGRFMVSGLT----LKVADPRRL 1055

Query: 430  DFKQE--RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            DF+       ++ V   D  G S      +NI + N       +   T  V E+   G  
Sbjct: 1056 DFEGVGGAMCLIDVECRDQDGGSVQQQFVVNIMNENEAPTRVLSESGTFEVPENHSPGYI 1115

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V  + A D D   N   TY L S  +   V      F I+     ITT +L D E+   Y
Sbjct: 1116 VAKLLAEDQDS--NDNFTYLLQSSKNTSNVP-----FTIHGNR-LITTARL-DYESRDTY 1166

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            ++ VT  D G  + S T  + + V+DVND          TA + E++ + T V ++   D
Sbjct: 1167 VINVTCVDSG--NFSVTQALLVQVLDVNDVPSEIVVPPGTA-VTENSEMSTLVVELRTLD 1223

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGV-IRTNKALDRESVATHDLKAVAIDGGTP- 665
             D+G   + H  +       G+  +   + + +  +  +D ESV    L     D G P 
Sbjct: 1224 EDLG---QTHKYIIHSQSPIGALELRETNKLHVADSSKIDYESVPYIHLTISTTDNGRPT 1280

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            P +   I+ I I D N+ P   +   L+  + EN+ +GT +G I   DPD  P A     
Sbjct: 1281 PLTKVTILKIPILDTNEKPTDIKLSPLS--MRENAAVGTIVGTITVIDPDTFPQAFTCLL 1338

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785
            +   D    F +          +   + LDYE  R     +        W      + V 
Sbjct: 1339 V--DDAEGRFRIVHNNTKIDLAIGNGLALDYEKHRSHNITIKCTDGGGFWCQREFVLDVL 1396

Query: 786  DVND 789
            D ND
Sbjct: 1397 DAND 1400



 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 115/485 (23%), Positives = 189/485 (38%), Gaps = 37/485 (7%)

Query: 99   LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
            LLT   LD EK   + +     D  +P S ++S   T  + +I+ N+  P     T    
Sbjct: 946  LLTARPLDYEKAQNHNITFNIRD--TPYS-QISVNQTFIIAVINVNEP-PSAINLTNKNI 1001

Query: 159  VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
            V+     T   VI ++   D D           +  +   +F +  L+  V+  + LD+E
Sbjct: 1002 VENSPRGT---VIGRLIVEDPDEPFLPQSFVCNLRNDAYGRFMVSGLTLKVADPRRLDFE 1058

Query: 219  QVRSYRLVI----RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
             V     +I    R QDGGS  +    Q ++NI + N+   R  +      V EN   GY
Sbjct: 1059 GVGGAMCLIDVECRDQDGGSVQQ----QFVVNIMNENEAPTRVLSESGTFEVPENHSPGY 1114

Query: 275  SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
             + ++ A D D   N   TY +     T NV  P TI      + T+ +LD E++  Y +
Sbjct: 1115 IVAKLLAEDQDS--NDNFTYLLQSSKNTSNV--PFTI--HGNRLITTARLDYESRDTYVI 1168

Query: 335  LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
             VT  D G+   +                    PG     + E+    T VV L   D D
Sbjct: 1169 NVTCVDSGNFSVTQALLVQVLDVNDVPSEIVVPPG---TAVTENSEMSTLVVELRTLDED 1225

Query: 395  EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSD 451
                  Y I   +  G   +   N +  +  +  +D++      LT+S TD+G     + 
Sbjct: 1226 LGQTHKYIIHSQSPIGALELRETN-KLHVADSSKIDYESVPYIHLTISTTDNGRPTPLTK 1284

Query: 452  TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
              +++I I D N      + +P   S+ E+A +GT V  ++  D D    A     +   
Sbjct: 1285 VTILKIPILDTNEKPTDIKLSP--LSMRENAAVGTIVGTITVIDPDTFPQAFTCLLVDDA 1342

Query: 512  ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
                 + H++ +  +     AI     LD E    + +T+   DGG        +  + V
Sbjct: 1343 EGRFRIVHNNTKIDL-----AIGNGLALDYEKHRSHNITIKCTDGG--GFWCQREFVLDV 1395

Query: 572  VDVND 576
            +D ND
Sbjct: 1396 LDAND 1400



 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 168/683 (24%), Positives = 272/683 (39%), Gaps = 82/683 (12%)

Query: 138  VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
            VNI+++N+   +   ++ T  V E+ S     ++AK+ A D D   N           + 
Sbjct: 1085 VNIMNENEAPTRVLSESGTFEVPENHS--PGYIVAKLLAEDQDSNDNFTYLLQSSKNTSN 1142

Query: 198  MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
            + F+I      +     LDYE   +Y + +   D G+   S T  LL+ + DVND  P  
Sbjct: 1143 VPFTIHG--NRLITTARLDYESRDTYVINVTCVDSGN--FSVTQALLVQVLDVND-VPSE 1197

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
                   +V+EN  +   +V ++  D D G   +  Y +  +   G ++L  T       
Sbjct: 1198 IVVPPGTAVTENSEMSTLVVELRTLDEDLGQTHK--YIIHSQSPIGALELRET---NKLH 1252

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            V  S ++D E+     L ++ TD G P      T               +     + + E
Sbjct: 1253 VADSSKIDYESVPYIHLTISTTDNGRPTPLTKVTILKIPILDTNEKPTDIKLS-PLSMRE 1311

Query: 378  DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN-------GRGL-------- 422
            +   GT V T+T  D D   +    +   +  GRF I   N       G GL        
Sbjct: 1312 NAAVGTIVGTITVIDPDTFPQAFTCLLVDDAEGRFRIVHNNTKIDLAIGNGLALDYEKHR 1371

Query: 423  ---ITV--AQPLDFKQERRYVLTV-SATDS-------GGRSDTAMVQ--INITDA--NNY 465
               IT+       F  +R +VL V  A D+         R DT + Q  +NI+ A   N 
Sbjct: 1372 SHNITIKCTDGGGFWCQREFVLDVLDANDAPSNVIFIDARGDTTLDQARVNISSALATNT 1431

Query: 466  APVF---ENA-------PYTASVFEDAPIGT---TVLVVSATDSD--VGINA---QITYS 507
             PV    E+A        Y   + ED        T  ++S  D+   V +NA   Q  +S
Sbjct: 1432 VPVAAVNESAVAGITLVSYVHVIDEDTSHTAQKHTCGLISEEDAQLYVTVNAYRPQSDFS 1491

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
                 S E+ +    +F+I P T +I   + LD E  +   + +   D G P LS    +
Sbjct: 1492 RRKRRSTES-SRVPTEFMIQPGTNSIVVREKLDYEARTNLTIFLKCTDNGSPQLSTVAYL 1550

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            ++ V+DV   E      L +  I E++  GT V  +  TD D   +    Y L+   +  
Sbjct: 1551 KVYVLDV--AEAPTDLTLSSLVIKENSPEGTLVGSITVTDPDSAPSA---YSLEVTSQGV 1605

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
               ++   + V  +   LD E      ++    +  T  Q  T   HI I DIN++P   
Sbjct: 1606 PFRLV--GNDVFVSRHPLDHERTPVITIQVTVREVFTSLQ-FTKSFHINISDINEAPSKV 1662

Query: 688  ESD-CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
              D   +  + E+  +G TIG+    D D   + +   S+ GG +++ F++  R G+   
Sbjct: 1663 TLDGKASVTVLESVTVGHTIGQFVVEDED-NYDKIFAISL-GGSNASDFAV--RDGA--- 1715

Query: 747  ELVTMVDLDYESPRKKYELVIRA 769
             LV    LD  S   +Y L +RA
Sbjct: 1716 -LVVTSQLDAWS-IDRYTLAVRA 1736



 Score = 75.4 bits (177), Expect = 6e-13
 Identities = 157/753 (20%), Positives = 295/753 (39%), Gaps = 78/753 (10%)

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           TL+ +             +  F +D   G L+    +D E   ++ + V +TD  +P   
Sbjct: 209 TLDVDSRQSHSYTMVDSAEGTFGVDNSLGVLVVVREMDFETHPQFFIQVMSTDSGTPP-- 266

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            LS      ++++D N+  P          V E+ SV  +  I  + + DAD   N  + 
Sbjct: 267 -LSHVQNFTIDVMDVNE--PPTPPVLAPPVVYENASV--HSTIGLLSSHDADADTN--LT 319

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y ++  + +  F ++     + L   L YE    Y + ++ +D G+P    +  + + + 
Sbjct: 320 YTLLT-DARGTFRVEE--SRLVLNSPLSYETQSRYTITVQVRDNGNPILVASQAINVTVF 376

Query: 249 DVNDNAPR-FYTSLFQESVSENVPI-----GYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           D ND      +     +  S++  +     G  +  + A D D   +  +   +T     
Sbjct: 377 DCNDPPTGVIFNGGSLDEYSDDPDVNGTRNGTHVGTLTAIDED-AKDTHVFEILTQGS-- 433

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
                P  I   +  V  + +LD E++  + LL+  TD      +A+ T           
Sbjct: 434 -----PFRIHNSTVIVGNARRLDFESRNTWTLLIRVTD----QVAASVTSSIRIFLSDIN 484

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               M        +E+ P GT + +L+  D D  +R  + +   ++       S NG  L
Sbjct: 485 EPPTMISLSSDSFSENAPVGTLIGSLSTQDPDAQDRHRFSLETSSSNS----VSINGSNL 540

Query: 423 ITVAQPLDFKQERRYV-LTVSATDSGGRSDTAMVQINITDANNYAPVFE-------NAPY 474
           I V + +DF+     + + V   DSG  +   +  I +T++N      E       +   
Sbjct: 541 I-VNKVVDFETVLNPLSIQVKVRDSGNLTRNQVFNITVTNSNEAPTSIELTSQLSCSPGV 599

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
           T  V E+   G  V  ++  D D G       +    +++E     D++ ++   TG   
Sbjct: 600 TLCVPENKLAGYPVAYINVKDPDDG-----DVTTCDVMTDEFFGIRDKELIV---TGNTN 651

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
              L     +S   + +  RD G   LS   D  IS++D ND         Y A+  + A
Sbjct: 652 YEALTSDHVVS---VGIFCRDKG--GLSAQADYNISILDANDAPTQVFLSHYIAS--DSA 704

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
            VG+ V +    D D       HY +          + +     +R  K+L   +     
Sbjct: 705 PVGSLVGRFTVEDEDAS---DTHYCILLTQNS----LFEILGLELRVKKSLKNATATRQP 757

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           ++    D  +   +   +  I+++++N S  +      +  ISEN   G+ +G I A   
Sbjct: 758 VRVWCYDRTSV--AFPQLFFIEVQNLNMSAQI-NITIDSSEISENKAPGSVVGRIHALSY 814

Query: 715 DEGPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---A 770
           D  P   + + +   DD N +F+L +   ++   LVT   LDYE+ R +Y +V+R    A
Sbjct: 815 D--PTETLVFDLD--DDCNGTFALTSGNTANTRMLVTTRPLDYET-RPQYTVVVRVRGNA 869

Query: 771 SPPLWNDVRVEIL-VTDVNDNAPVMKDFQIIFN 802
               + +  + +L VT+  D+  V+    ++ N
Sbjct: 870 ERTSFREFTISVLDVTEFPDDYLVLHHSSVVEN 902



 Score = 62.1 bits (144), Expect = 6e-09
 Identities = 59/249 (23%), Positives = 112/249 (44%), Gaps = 23/249 (9%)

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
           GYLL +        ++      +   +D   N P     + + ++ E++ +G+ V ++  
Sbjct: 150 GYLLGINNITCQSSAIWSIIRAQCEDLDPGSNRPPSAILISSDSVPENSPLGSVVGKLTT 209

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            D D     R  +     D  EG+F +D + GV+   + +D E+     ++ ++ D GTP
Sbjct: 210 LDVD----SRQSHSYTMVDSAEGTFGVDNSLGVLVVVREMDFETHPQFFIQVMSTDSGTP 265

Query: 666 PQSSTVIVHIKIEDIND--SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
           P S      I + D+N+  +PPV         + EN+ + +TIG + +HD D   N  + 
Sbjct: 266 PLSHVQNFTIDVMDVNEPPTPPVLAPP----VVYENASVHSTIGLLSSHDADADTN--LT 319

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780
           Y++   D   +F +E      ++ LV    L YE+ + +Y + ++     +P L     +
Sbjct: 320 YTLL-TDARGTFRVE------ESRLVLNSPLSYET-QSRYTITVQVRDNGNPILVASQAI 371

Query: 781 EILVTDVND 789
            + V D ND
Sbjct: 372 NVTVFDCND 380



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 81/377 (21%), Positives = 149/377 (39%), Gaps = 25/377 (6%)

Query: 88   DVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
            +V  ID R    L +A ++    +A  TV V A ++++     L S    +V++ID++ +
Sbjct: 1404 NVIFIDARGDTTLDQARVNISSALATNTVPVAAVNESAVAGITLVS----YVHVIDEDTS 1459

Query: 147  YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            +   + + +T  +   IS  D  +   + A       +   R +        +F I   +
Sbjct: 1460 H---TAQKHTCGL---ISEEDAQLYVTVNAYRPQSDFSRRKRRSTESSRVPTEFMIQPGT 1513

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
              + + + LDYE   +  + ++  D GSP  S    L + + DV + AP   T L    +
Sbjct: 1514 NSIVVREKLDYEARTNLTIFLKCTDNGSPQLSTVAYLKVYVLDVAE-APTDLT-LSSLVI 1571

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
             EN P G  +  +   D D   +A   Y++   + T    +P  +     +V +   LD 
Sbjct: 1572 KENSPEGTLVGSITVTDPDSAPSA---YSL---EVTSQ-GVPFRLVGNDVFV-SRHPLDH 1623

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
            E      + VT  +     +   +                + G+  V + E    G  + 
Sbjct: 1624 ERTPVITIQVTVREVFTSLQFTKSFHINISDINEAPSKVTLDGKASVTVLESVTVGHTIG 1683

Query: 387  TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
                 D D  +++     GG+    F++      G + V   LD     RY L V ATD 
Sbjct: 1684 QFVVEDEDNYDKIFAISLGGSNASDFAVRD----GALVVTSQLDAWSIDRYTLAVRATDR 1739

Query: 447  GGRSDTAMVQINITDAN 463
            GG S T+M+ + + + +
Sbjct: 1740 GGLSTTSMITVIVKEVD 1756



 Score = 59.3 bits (137), Expect = 4e-08
 Identities = 112/462 (24%), Positives = 182/462 (39%), Gaps = 56/462 (12%)

Query: 54  KNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113
           +NA V  TI L+++   + +             +  FR++     L+  + L  E  +RY
Sbjct: 296 ENASVHSTIGLLSSHDADAD--TNLTYTLLTDARGTFRVE--ESRLVLNSPLSYETQSRY 351

Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDND--NYPQFSEKTY-TVSVDEDISVTDNPV 170
           T+ V+  D  +P+   L ++  I+V + D ND      F+  +    S D D++ T N  
Sbjct: 352 TITVQVRDNGNPI---LVASQAINVTVFDCNDPPTGVIFNGGSLDEYSDDPDVNGTRNGT 408

Query: 171 -IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
            +  + A D D            G      F I + +  V   + LD+E   ++ L+IR 
Sbjct: 409 HVGTLTAIDEDAKDTHVFEILTQGS----PFRIHNSTVIVGNARRLDFESRNTWTLLIRV 464

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDADEG 287
            D    + S T+ + I + D+N+  P    SL  +S SEN P+G  I  +  Q  DA + 
Sbjct: 465 TD--QVAASVTSSIRIFLSDINE--PPTMISLSSDSFSENAPVGTLIGSLSTQDPDAQDR 520

Query: 288 VNAEL-TYTMTDKDYTGN-------VDLPITIDPRSGWVYT--SGQLDRETQAKYQLLVT 337
               L T +       G+       VD    ++P S  V    SG L R         +T
Sbjct: 521 HRFSLETSSSNSVSINGSNLIVNKVVDFETVLNPLSIQVKVRDSGNLTRNQVFN----IT 576

Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397
            T+  + P S   T                PG   + + E++  G PV  +   D D+ +
Sbjct: 577 VTNSNEAPTSIELTSQLSCS----------PG-VTLCVPENKLAGYPVAYINVKDPDDGD 625

Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS--ATDSGGRSDTAMV 455
               ++    T   F I  +    LI             +V++V     D GG S  A  
Sbjct: 626 VTTCDVM---TDEFFGIRDKE---LIVTGNTNYEALTSDHVVSVGIFCRDKGGLSAQADY 679

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            I+I DAN+       + Y AS  + AP+G+ V   +  D D
Sbjct: 680 NISILDANDAPTQVFLSHYIAS--DSAPVGSLVGRFTVEDED 719



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 68/294 (23%), Positives = 105/294 (35%), Gaps = 25/294 (8%)

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +  V     I P +  +    +LD E +    + +  TD G P  S  A           
Sbjct: 1500 SSRVPTEFMIQPGTNSIVVREKLDYEARTNLTIFLKCTDNGSPQLSTVAYLKVYVLDVAE 1559

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGR 420
                       ++  E+ P GT V ++T TD D   +    E+T      R       G 
Sbjct: 1560 APTDLTLSSLVIK--ENSPEGTLVGSITVTDPDSAPSAYSLEVTSQGVPFRLV-----GN 1612

Query: 421  GLITVAQPLDFKQERRYVLTVSATDS---GGRSDTAMVQINITDANNY-APVFENAPYTA 476
             +     PLD   ER  V+T+  T          T    INI+D N   + V  +   + 
Sbjct: 1613 DVFVSRHPLD--HERTPVITIQVTVREVFTSLQFTKSFHINISDINEAPSKVTLDGKASV 1670

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            +V E   +G T+      D D   N    +++S   SN +       F +  + GA+   
Sbjct: 1671 TVLESVTVGHTIGQFVVEDED---NYDKIFAISLGGSNAS------DFAV--RDGALVVT 1719

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
              LD  ++  Y L V A D G  S +    V +  VD+  N      Q   A +
Sbjct: 1720 SQLDAWSIDRYTLAVRATDRGGLSTTSMITVIVKEVDLCANTSSCSPQATCARV 1773



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 38/173 (21%), Positives = 60/173 (34%), Gaps = 19/173 (10%)

Query: 1532 WDSSTCTCEAGRVGPQC---VSACELGPC---GAARCVPDQTPKGYSCACEPGYT--LTT 1583
            W + TC C+ G   P C   ++ C   PC   G++RC  +    G+ C C  G+T     
Sbjct: 1820 WKNYTCPCKPGWSPPNCKADINECLSNPCNSSGSSRC--ENLENGFQCTCRAGFTGKYCE 1877

Query: 1584 SGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHCKENHYKPEGTAECL 1642
            +   +  K+ C  G           C     +   +C+ ++  C    +     GT    
Sbjct: 1878 TDVDDCEKDSCLNGGLCVDKTNGFICVCKEPFIGVNCDTDDTICRQNASICPHNGTCISY 1937

Query: 1643 P-------CQCYAA-GSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPN 1687
            P       C C     S+ + C    G   C+P       D C   +    PN
Sbjct: 1938 PEDATKHTCLCSIPWSSDCNGCALGYGGADCKPCQYPWTGDNCLQDWRNCEPN 1990



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 50/169 (29%), Positives = 61/169 (36%), Gaps = 20/169 (11%)

Query: 1526 SKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCAC-EP--G 1578
            S+C    +   CTC AG  G  C   V  CE   C     CV D+T  G+ C C EP  G
Sbjct: 1854 SRCENLENGFQCTCRAGFTGKYCETDVDDCEKDSCLNGGLCV-DKT-NGFICVCKEPFIG 1911

Query: 1579 YTLTTSGCI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEG 1637
                T   I       CP        C     D T+         +  C+     Y   G
Sbjct: 1912 VNCDTDDTICRQNASICP----HNGTCISYPEDATKHTCLCSIPWSSDCNGCALGY---G 1964

Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686
             A+C PCQ Y    +N  C      C   P + G  C   +N YA V P
Sbjct: 1965 GADCKPCQ-YPWTGDN--CLQDWRNCEPNPCLHGGTCYPLSNEYACVCP 2010



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 9/86 (10%)

Query: 1507 VRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV----GPQC--VSACELGPCGAA 1560
            V + C    +C  S+ P   +CV +  S  C C +G +    G  C  V+ C     G  
Sbjct: 26   VNNTCDDVNECQSSLNPCSQRCVNTRGSLYCACSSGFLLLGDGFTCRDVNECSQSGHGCE 85

Query: 1561 R-CVPDQTPKGYSCACEPGYTLTTSG 1585
            + C+   T   Y+C CE GY L  +G
Sbjct: 86   QHCM--NTVGSYTCICELGYKLGQNG 109



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 19/126 (15%)

Query: 1528 CVTSWDSSTCTCEAG----RVGPQC--VSACE--LGPCGAARCVPDQTPKGYSCACEPGY 1579
            C+ +  S TCTC +G     V   C  V+ C+  L PC + RCV   T     CAC  G+
Sbjct: 6    CINTIGSFTCTCASGLIYNPVNNTCDDVNECQSSLNPC-SQRCV--NTRGSLYCACSSGF 62

Query: 1580 TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN-----KENGKCHCKENHYK 1634
             L   G       EC      G  C     +    Y   C       +NG+   + +   
Sbjct: 63   LLLGDGFTCRDVNECS---QSGHGCEQHCMNTVGSYTCICELGYKLGQNGRSCERVDCGI 119

Query: 1635 PEGTAE 1640
            PEGT+E
Sbjct: 120  PEGTSE 125



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 17/114 (14%)

Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
            P   SC C  G+T   +G I +  + C P      +  G C  D   G+      +N  C
Sbjct: 1775 PGRASCTCRVGFT--GNGHICNDIDFCAPNPCHPDNTIGECQ-DGFGGW------KNYTC 1825

Query: 1627 HCKENHYKPEGTA---ECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACD 1675
             CK     P   A   ECL   C ++GS  S CE      QC CR G  G+ C+
Sbjct: 1826 PCKPGWSPPNCKADINECLSNPCNSSGS--SRCENLENGFQCTCRAGFTGKYCE 1877



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 10/109 (9%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGI-LCQGCSIDAAYTT 1100
            F C C  GFTG  CET +    CE D     C +G  CV +  G I +C+   I     T
Sbjct: 1863 FQCTCRAGFTGKYCETDVD--DCEKDS----CLNGGLCVDKTNGFICVCKEPFIGVNCDT 1916

Query: 1101 --AVCELRARSFPVS-SFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG 1146
               +C   A   P + + +++P    +H     + +++      L Y G
Sbjct: 1917 DDTICRQNASICPHNGTCISYPEDATKHTCLCSIPWSSDCNGCALGYGG 1965



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/39 (35%), Positives = 17/39 (43%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C    C NG  C D  + +IC CKE   G +C
Sbjct: 1876 CETDVDDCEKDSCLNGGLCVDKTNGFICVCKEPFIGVNC 1914



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 2/41 (4%)

Query: 1310 CPEKRSRCSSAPCYNG--AECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC +   + C +L + + C C+ G TGK C
Sbjct: 1836 CKADINECLSNPCNSSGSSRCENLENGFQCTCRAGFTGKYC 1876


>SB_21336| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 120

 Score =  101 bits (243), Expect = 6e-21
 Identities = 56/126 (44%), Positives = 74/126 (58%), Gaps = 7/126 (5%)

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P+F++  +  SV E   +GT  L VSATD D G N+ +TYS+       AV + +  F I
Sbjct: 2   PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------AVGNEEGFFSI 54

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           N +TGAI+  K LDRET   Y LTV A+DGG P L+ TT V I V D NDN PV +  + 
Sbjct: 55  NNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVI 114

Query: 587 TANIME 592
             ++ E
Sbjct: 115 QVSLSE 120



 Score = 92.3 bits (219), Expect = 5e-18
 Identities = 49/121 (40%), Positives = 70/121 (57%), Gaps = 2/121 (1%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G
Sbjct: 2   PLFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTG 59

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    ++ Q S+S
Sbjct: 60  AISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLS 119

Query: 268 E 268
           E
Sbjct: 120 E 120



 Score = 82.2 bits (194), Expect = 5e-15
 Identities = 44/120 (36%), Positives = 64/120 (53%), Gaps = 1/120 (0%)

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           P+F+   +  ++ E   +GT    V ATD D G N  + Y +     EEG F I+  +G 
Sbjct: 2   PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AVGNEEGFFSINNKTGA 60

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           I   K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV +   +   +SE
Sbjct: 61  ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 120



 Score = 65.7 bits (153), Expect = 5e-10
 Identities = 45/119 (37%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F    + V + E E  GT  +T++ATD D   ++ L Y I  GN  G FSI   N  G I
Sbjct: 4   FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSIN--NKTGAI 61

Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           +VA+ LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    S+ E
Sbjct: 62  SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 120



 Score = 64.9 bits (151), Expect = 9e-10
 Identities = 36/95 (37%), Positives = 55/95 (57%), Gaps = 4/95 (4%)

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P F +  F  SV+E   +G   + V A D D G N+ LTY++      GN +   +I+ +
Sbjct: 2   PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----VGNEEGFFSINNK 57

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
           +G +  + QLDRET+ +Y L V A DGG+PP ++T
Sbjct: 58  TGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 92



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 8/115 (6%)

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
           P+F+S      ++E   +GT    + A D D G N+ + YSI  G++   FS+  + G+ 
Sbjct: 2   PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA- 60

Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796
              +     LD E+ R +Y L + A     PPL +   V I V D NDN PV++D
Sbjct: 61  ---ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 111



 Score = 58.4 bits (135), Expect = 8e-08
 Identities = 42/142 (29%), Positives = 64/142 (45%), Gaps = 22/142 (15%)

Query: 20  SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79
           +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I +   +           
Sbjct: 1   TPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGF--------- 51

Query: 80  XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139
                     F I+ ++GA+     LDRE   +YT+ V A D   P    L+ST  + + 
Sbjct: 52  ----------FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PLNSTTAVAIQ 98

Query: 140 IIDDNDNYPQFSEKTYTVSVDE 161
           + D NDN P   +    VS+ E
Sbjct: 99  VGDANDNPPVIQDAVIQVSLSE 120



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 16/53 (30%), Positives = 24/53 (45%)

Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           DA     L Y I  GN      +N  TG+++++ QL+       T+ V   DG
Sbjct: 32  DAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 84


>SB_36411| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 654

 Score = 96.7 bits (230), Expect = 2e-19
 Identities = 62/179 (34%), Positives = 93/179 (51%), Gaps = 15/179 (8%)

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
           N + PVF++  Y  SV E++P G++VL V+ATD D G N ++ Y L+   +NEA    D 
Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLA---TNEA----DM 282

Query: 523 QFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
            F ++  +G I T+ +LD E +     Y   VTA D G P    +T V ++++DVNDN P
Sbjct: 283 PFTVDGLSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCP 342

Query: 580 VFKQQLYTA-NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
           VF   + T  N+      GT +  +  TD D G N  + Y +       G   +D  +G
Sbjct: 343 VFDPSIRTTYNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSVS----ANGVIAVDAVTG 397



 Score = 91.1 bits (216), Expect = 1e-17
 Identities = 53/156 (33%), Positives = 85/156 (54%), Gaps = 5/156 (3%)

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
           N + PVF+   Y  +++E++  G+SV +V ATD D G NG + Y L   + +   F +D 
Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADM-PFTVDG 288

Query: 635 ASGVIRTNKALDRESVATHDL---KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
            SG I T+  LD E++    L      A D G P + ++  V++ + D+ND+ PVF+   
Sbjct: 289 LSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFDPSI 348

Query: 692 LTFY-ISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            T Y +S ++  GT +  I   D D G N++V YS+
Sbjct: 349 RTTYNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSV 384



 Score = 86.6 bits (205), Expect = 3e-16
 Identities = 63/202 (31%), Positives = 98/202 (48%), Gaps = 29/202 (14%)

Query: 17  NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
           N H PVF+   Y  SV E +  G++VL + ATD+D G+N EV Y +    AD        
Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADM------- 282

Query: 77  XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSST 133
                        F +DG SG ++T + LD E + R   YT  V A+D   P+  + +ST
Sbjct: 283 ------------PFTVDGLSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPM--KFAST 328

Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
             ++VN++D NDN P F     T + +  +       +  I  TD D G NS + Y++  
Sbjct: 329 R-VYVNLLDVNDNCPVFDPSIRT-TYNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSVSA 386

Query: 194 GNTQMQFSIDSLSGDVSLVKTL 215
                  ++D+++G +SL+  L
Sbjct: 387 NGV---IAVDAVTGSLSLIGQL 405



 Score = 82.2 bits (194), Expect = 5e-15
 Identities = 49/154 (31%), Positives = 79/154 (51%), Gaps = 6/154 (3%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P F    Y VSV E+ S   + V+ ++ ATD D G N  +RY +      M F++D LSG
Sbjct: 234 PVFQSTYYNVSVVEN-SPPGSSVL-RVNATDEDSGRNGEVRYFLATNEADMPFTVDGLSG 291

Query: 208 DVSLVKTLDYEQV---RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL-FQ 263
           ++     LDYE +     Y   + A D G P +  +T++ +N+ DVNDN P F  S+   
Sbjct: 292 EIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFDPSIRTT 351

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            ++S +   G  +  +   D D G N+ + Y+++
Sbjct: 352 YNLSVHTAPGTQLDVITTTDKDAGYNSIVIYSVS 385



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 49/148 (33%), Positives = 68/148 (45%), Gaps = 8/148 (5%)

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           N + P F ++ +  SV EN P G S++RV A D D G N E+ Y +     T   D+P T
Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLA----TNEADMPFT 285

Query: 311 IDPRSGWVYTSGQLDRETQAK---YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
           +D  SG + TS  LD E   +   Y   VTA+D G P + A+                F 
Sbjct: 286 VDGLSGEIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFD 345

Query: 368 PG-QYEVELAEDEPPGTPVVTLTATDAD 394
           P  +    L+    PGT +  +T TD D
Sbjct: 346 PSIRTTYNLSVHTAPGTQLDVITTTDKD 373



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 46/155 (29%), Positives = 78/155 (50%), Gaps = 14/155 (9%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F    Y V + E+ PPG+ V+ + ATD D   +  + Y +        F++   +G   I
Sbjct: 236 FQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADMPFTVDGLSGE--I 293

Query: 424 TVAQPLDFK---QERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE---NAPYT 475
             +  LD++   ++  Y   V+A+D+G   +  +  V +N+ D N+  PVF+      Y 
Sbjct: 294 VTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFDPSIRTTYN 353

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            SV   AP GT + V++ TD D G N+ + YS+S+
Sbjct: 354 LSV-HTAP-GTQLDVITTTDKDAGYNSIVIYSVSA 386



 Score = 64.9 bits (151), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 11/181 (6%)

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
           N  PPVF+S      + ENSP G+++  + A D D G N  V Y +   +    F+++  
Sbjct: 230 NLHPPVFQSTYYNVSVVENSPPGSSVLRVNATDEDSGRNGEVRYFLATNEADMPFTVDGL 289

Query: 741 QGSDKAELVTMVDLDYES-PRKK-YELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM- 794
            G    E+VT   LDYE+ PRK  Y   + A+    P  +   RV + + DVNDN PV  
Sbjct: 290 SG----EIVTSSVLDYEAIPRKHLYTFDVTASDNGRPMKFASTRVYVNLLDVNDNCPVFD 345

Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
              +  +N      P      +   D D        I S +   +I ++  TGS++L  Q
Sbjct: 346 PSIRTTYNLSVHTAPGTQLDVITTTDKDAGYN-SIVIYSVSANGVIAVDAVTGSLSLIGQ 404

Query: 855 L 855
           L
Sbjct: 405 L 405



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 63/233 (27%), Positives = 87/233 (37%), Gaps = 57/233 (24%)

Query: 1517 CMLSICPPYSKCVTSWD---SSTCTCEAGRVGPQC--VSACE-LGPCGA-ARCVPDQTPK 1569
            C +  C   S+C +  D   S+TC C  G  G +C  V+ C   G C     CV D+   
Sbjct: 73   CAVPDCAAVSQCSSHGDCVASNTCRCHPGYQGSRCSEVADCSSFGNCSFHGECVIDRGGN 132

Query: 1570 GYSCACEPGYT---LTTSGCIE----SGKEECPGGWWGGSACGPCACDVTRGYH-PHCNK 1621
              +C C  G++      + CI+    S + EC          G C CDV  GY  P C+ 
Sbjct: 133  A-TCRCYTGFSGSECQLASCIKVKNCSNRGEC-------FESGFCKCDV--GYTGPDCSN 182

Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
             +    C+  +Y       C  C      S+   C  A   C C PG  G +C+  A   
Sbjct: 183  NS----CEAINY-------CSDCTAVQECSKRGYC-MAPDTCECYPGWDGPSCNKKA--- 227

Query: 1682 AEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDE 1734
               TPN    V              +  T + V  + + PPGSS       DE
Sbjct: 228  ---TPNLHPPV--------------FQSTYYNVSVVENSPPGSSVLRVNATDE 263



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 31/122 (25%), Positives = 41/122 (33%), Gaps = 7/122 (5%)

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP-CACDVTRGYHPHCNKENGKCHCKE 1630
            SCA +  Y      C+ + + EC  GW G S   P CA       H  C   N  C C  
Sbjct: 43   SCA-DLDYCSGRGSCVNAYRCECNSGWTGISCAVPDCAAVSQCSSHGDCVASN-TCRCHP 100

Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSC---EAATGQCHCRPGVIGRACDACANAYAEVTPN 1687
              Y+    +E   C  +   S +  C         C C  G  G  C   +    +   N
Sbjct: 101  G-YQGSRCSEVADCSSFGNCSFHGECVIDRGGNATCRCYTGFSGSECQLASCIKVKNCSN 159

Query: 1688 SG 1689
             G
Sbjct: 160  RG 161



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 10/77 (12%)

Query: 1513 SRADCMLSICPPYSKCVTS---WDSSTCTCEAGRVGPQCV-SACE-LGPCGAARCVPDQT 1567
            S ++C L+ C     C      ++S  C C+ G  GP C  ++CE +  C     V + +
Sbjct: 142  SGSECQLASCIKVKNCSNRGECFESGFCKCDVGYTGPDCSNNSCEAINYCSDCTAVQECS 201

Query: 1568 PKGY-----SCACEPGY 1579
             +GY     +C C PG+
Sbjct: 202  KRGYCMAPDTCECYPGW 218



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 5/55 (9%)

Query: 11  INVLDCNDHSPVFE---MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           +N+LD ND+ PVF+      Y  SV    + GT +  +  TD+D G N+ V Y++
Sbjct: 332 VNLLDVNDNCPVFDPSIRTTYNLSVH--TAPGTQLDVITTTDKDAGYNSIVIYSV 384



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 3/41 (7%)

Query: 1315 SRCSSAPCYNGAECS---DLWDTYICDCKEGHTGKDCADST 1352
            S C  A C     CS   + +++  C C  G+TG DC++++
Sbjct: 144  SECQLASCIKVKNCSNRGECFESGFCKCDVGYTGPDCSNNS 184


>SB_15158| Best HMM Match : Cadherin (HMM E-Value=7.5e-23)
          Length = 390

 Score = 96.3 bits (229), Expect = 3e-19
 Identities = 63/161 (39%), Positives = 85/161 (52%), Gaps = 3/161 (1%)

Query: 556 GGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
           GGV  S +  T V I V DV+D   VF    YTA + E +  G  V+ V A D D+ LN 
Sbjct: 204 GGVNGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNK 263

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            + Y +D       +FVI   +GVI  NK LDRE+VA ++L+  AI   T  ++    V 
Sbjct: 264 PVSYFIDQVTNPGEAFVIINTTGVITVNKPLDRETVAFYNLRVGAI--STIHKAVFATVQ 321

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
           I I DIND+ P F +   +  + ENSP G T+  + A D D
Sbjct: 322 ITITDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDAD 362



 Score = 87.8 bits (208), Expect = 1e-16
 Identities = 57/164 (34%), Positives = 86/164 (52%), Gaps = 8/164 (4%)

Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
           +G R+    V I + D ++   VF    YTA V E +  G  V  V+A D D+ +N  ++
Sbjct: 207 NGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNKPVS 266

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
           Y +      + V +  + FVI   TG IT NK LDRET++ Y L V A      ++  T 
Sbjct: 267 YFI------DQVTNPGEAFVIINTTGVITVNKPLDRETVAFYNLRVGAISTIHKAVFAT- 319

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            V+I++ D+NDN P F    Y+  + E++  G +V +V A DAD
Sbjct: 320 -VQITITDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDAD 362



 Score = 78.6 bits (185), Expect = 7e-14
 Identities = 53/142 (37%), Positives = 80/142 (56%), Gaps = 12/142 (8%)

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
           L GT V  V A D +   N +I Y+L  +D   G F I+  +G I +N  +DRE +   +
Sbjct: 67  LSGTGVLTVRAVDNE---NDQITYQLSGED---GRFKINSVTGEITSNVNIDREKLPGSN 120

Query: 655 L---KAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
           L   KA+A D  G        V V ++IED+ND+ PVF +   +  + EN+ +GTT   +
Sbjct: 121 LLEFKAIAYDAKGAGYDYRGDVPVRVQIEDVNDNTPVFINTPYSISVKENT-LGTTGFAV 179

Query: 710 RAHDPDEGPNAVVHYSIKGGDD 731
           +A D D+G NA++ YSI GG++
Sbjct: 180 KATDADQGQNALIKYSITGGNE 201



 Score = 78.6 bits (185), Expect = 7e-14
 Identities = 53/134 (39%), Positives = 72/134 (53%), Gaps = 3/134 (2%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NR-LHYEITGGNTRGRFSITSQNGRGLI 423
           F P  Y  ++AE    G  V T+TA D D   N+ + Y I      G   +   N  G+I
Sbjct: 230 FSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNKPVSYFIDQVTNPGEAFVII-NTTGVI 288

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           TV +PLD +    Y L V A  +  ++  A VQI ITD N+ AP F N PY+ +V E++P
Sbjct: 289 TVNKPLDRETVAFYNLRVGAISTIHKAVFATVQITITDINDNAPKFVNLPYSGTVPENSP 348

Query: 484 IGTTVLVVSATDSD 497
            G TVL V+A D+D
Sbjct: 349 TGLTVLRVTAQDAD 362



 Score = 72.9 bits (171), Expect = 3e-12
 Identities = 57/150 (38%), Positives = 74/150 (49%), Gaps = 20/150 (13%)

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           GT VL V A D++   N QITY LS E         D +F IN  TG IT+N  +DRE +
Sbjct: 69  GTGVLTVRAVDNE---NDQITYQLSGE---------DGRFKINSVTGEITSNVNIDREKL 116

Query: 545 SGYLL------TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            G  L         A+  G     D   V + + DVNDN PVF    Y+ ++ E+ L GT
Sbjct: 117 PGSNLLEFKAIAYDAKGAGYDYRGDVP-VRVQIEDVNDNTPVFINTPYSISVKENTL-GT 174

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEG 628
           +   V ATDAD G N  I Y +   + + G
Sbjct: 175 TGFAVKATDADQGQNALIKYSITGGNEDLG 204



 Score = 72.5 bits (170), Expect = 4e-12
 Identities = 62/177 (35%), Positives = 85/177 (48%), Gaps = 10/177 (5%)

Query: 131 SSTATIHVNI-IDDNDNYPQ-FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           S TA   V I ++D D+ P  FS   YT  V E  S T    +  + A D D+  N  + 
Sbjct: 209 SRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAE--SSTKGFYVTTVTARDGDLSLNKPVS 266

Query: 189 YAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           Y I    N    F I + +G +++ K LD E V  Y L + A      +   T Q  I I
Sbjct: 267 YFIDQVTNPGEAFVIINTTGVITVNKPLDRETVAFYNLRVGAISTIHKAVFATVQ--ITI 324

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE--GVNAELTYTMTDKDYT 302
            D+NDNAP+F    +  +V EN P G +++RV A DAD    ++ EL  T T   YT
Sbjct: 325 TDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDADSVCTLHCELK-TSTSSVYT 380



 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 83/316 (26%), Positives = 127/316 (40%), Gaps = 42/316 (13%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVL-VKATD-QASPVSDRLSSTATIHVNIIDDNDNY 147
           F+I+  +G + +  ++DREK+    +L  KA    A            + V I D NDN 
Sbjct: 96  FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRGDVPVRVQIEDVNDNT 155

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P F    Y++SV E+   T       +KATDAD            G N  +++SI   + 
Sbjct: 156 PVFINTPYSISVKENTLGTTG---FAVKATDADQ-----------GQNALIKYSITGGNE 201

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           D+                      G + SR+  T + I + DV+D    F    +   V+
Sbjct: 202 DLG---------------------GVNGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVA 240

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           E+   G+ +  V A D D  +N  ++Y +   D   N      I   +G +  +  LDRE
Sbjct: 241 ESSTKGFYVTTVTARDGDLSLNKPVSYFI---DQVTNPGEAFVIINTTGVITVNKPLDRE 297

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           T A Y L V A       ++  AT              F+   Y   + E+ P G  V+ 
Sbjct: 298 TVAFYNLRVGAI--STIHKAVFATVQITITDINDNAPKFVNLPYSGTVPENSPTGLTVLR 355

Query: 388 LTATDADEDNRLHYEI 403
           +TA DAD    LH E+
Sbjct: 356 VTAQDADSVCTLHCEL 371



 Score = 64.9 bits (151), Expect = 9e-10
 Identities = 62/196 (31%), Positives = 96/196 (48%), Gaps = 28/196 (14%)

Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ---ERRYV 438
           GT V+T+ A D +E++++ Y+++G +  GRF I S  G   IT    +D ++        
Sbjct: 69  GTGVLTVRAVD-NENDQITYQLSGED--GRFKINSVTGE--ITSNVNIDREKLPGSNLLE 123

Query: 439 LTVSATDSGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
               A D+ G     R D   V++ I D N+  PVF N PY+ SV E+  +GTT   V A
Sbjct: 124 FKAIAYDAKGAGYDYRGDVP-VRVQIEDVNDNTPVFINTPYSISVKENT-LGTTGFAVKA 181

Query: 494 TDSDVGINAQITYSLS-------------SEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           TD+D G NA I YS++             + +++  +   D   +    +    T K+ +
Sbjct: 182 TDADQGQNALIKYSITGGNEDLGGVNGSRTAVTSVFIRVEDVDDLPAVFSPDYYTAKVAE 241

Query: 541 RETMSGYLLTVTARDG 556
             T   Y+ TVTARDG
Sbjct: 242 SSTKGFYVTTVTARDG 257



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 15/142 (10%)

Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRL 225
           +  ++A D +   N  I Y + G + +  F I+S++G+++    +D E++       ++ 
Sbjct: 72  VLTVRAVDNE---NDQITYQLSGEDGR--FKINSVTGEITSNVNIDREKLPGSNLLEFKA 126

Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285
           +     G          + + I DVNDN P F  + +  SV EN  +G +   V+A DAD
Sbjct: 127 IAYDAKGAGYDYRGDVPVRVQIEDVNDNTPVFINTPYSISVKENT-LGTTGFAVKATDAD 185

Query: 286 EGVNAELTYTMTDKDYTGNVDL 307
           +G NA + Y++T     GN DL
Sbjct: 186 QGQNALIKYSITG----GNEDL 203



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 1/53 (1%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           ++ + D ND++PVF    Y  SV+E  + GTT   +KATD D G+NA ++Y+I
Sbjct: 145 RVQIEDVNDNTPVFINTPYSISVKEN-TLGTTGFAVKATDADQGQNALIKYSI 196



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD 51
           QI + D ND++P F    Y  +V E + +G TVL + A D D
Sbjct: 321 QITITDINDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDAD 362


>SB_57964| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 134

 Score = 95.9 bits (228), Expect = 4e-19
 Identities = 49/132 (37%), Positives = 77/132 (58%), Gaps = 7/132 (5%)

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           L+++A D D G+NA+I Y L   I ++       +F +N  TG IT  + +D E  S Y 
Sbjct: 8   LLLNARDKDEGVNAEIRYFLKDAIVSK-------RFSMNDTTGQITIKQAVDYEERSSYS 60

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
             V A DGG   L+ ++ V I+++DVNDN P F    Y   ++E+  +GT+V+QV A+D 
Sbjct: 61  FEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDL 120

Query: 609 DVGLNGRIHYEL 620
           D  LNG++ + +
Sbjct: 121 DSSLNGKVLFSI 132



 Score = 85.4 bits (202), Expect = 6e-16
 Identities = 41/135 (30%), Positives = 76/135 (56%), Gaps = 2/135 (1%)

Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
           S  ++P++  + A D D G N+ IRY +       +FS++  +G +++ + +DYE+  SY
Sbjct: 2   STLEDPLL--LNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTGQITIKQAVDYEERSSY 59

Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283
              + A DGG    + ++ + I I DVNDN P F  + +   + ENV IG ++ +V A D
Sbjct: 60  SFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASD 119

Query: 284 ADEGVNAELTYTMTD 298
            D  +N ++ +++ +
Sbjct: 120 LDSSLNGKVLFSILE 134



 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 6/125 (4%)

Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
           L A D DE  +  + Y +       RFS+    G+  IT+ Q +D+++   Y   V A+D
Sbjct: 10  LNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTGQ--ITIKQAVDYEERSSYSFEVFASD 67

Query: 446 SGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            G    + ++ V+I I D N+  P F    Y   + E+  IGTTV  V+A+D D  +N +
Sbjct: 68  GGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGK 127

Query: 504 ITYSL 508
           + +S+
Sbjct: 128 VLFSI 132



 Score = 62.1 bits (144), Expect = 6e-09
 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 3/125 (2%)

Query: 603 VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661
           + A D D G+N  I Y L  KD      F ++  +G I   +A+D E  +++  +  A D
Sbjct: 10  LNARDKDEGVNAEIRYFL--KDAIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFASD 67

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
           GG    + +  V I I D+ND+ P F        + EN  IGTT+ ++ A D D   N  
Sbjct: 68  GGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGK 127

Query: 722 VHYSI 726
           V +SI
Sbjct: 128 VLFSI 132



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 4/116 (3%)

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           + A D DEGVNAE+ Y + D      V    +++  +G +     +D E ++ Y   V A
Sbjct: 10  LNARDKDEGVNAEIRYFLKD----AIVSKRFSMNDTTGQITIKQAVDYEERSSYSFEVFA 65

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
           +DGG+   + +++              F+P +Y V+L E+   GT V  +TA+D D
Sbjct: 66  SDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLD 121



 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 39/150 (26%), Positives = 73/150 (48%), Gaps = 24/150 (16%)

Query: 43  LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102
           L L A D+D G NAE+ Y ++          DA          V   F ++  +G +  +
Sbjct: 8   LLLNARDKDEGVNAEIRYFLK----------DAI---------VSKRFSMNDTTGQITIK 48

Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
            ++D E+ + Y+  V A+D       RL+ ++++ + IID NDN P F    Y V + E+
Sbjct: 49  QAVDYEERSSYSFEVFASDGGEA---RLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVEN 105

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAII 192
           +++     + ++ A+D D   N  + ++I+
Sbjct: 106 VAI--GTTVTQVTASDLDSSLNGKVLFSIL 133



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 8/87 (9%)

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
           + A D DEG NA + Y +K    S  FS+    G    ++     +DYE  R  Y   + 
Sbjct: 10  LNARDKDEGVNAEIRYFLKDAIVSKRFSMNDTTG----QITIKQAVDYEE-RSSYSFEVF 64

Query: 769 AA---SPPLWNDVRVEILVTDVNDNAP 792
           A+      L     V I + DVNDN P
Sbjct: 65  ASDGGEARLTGSSSVRITIIDVNDNRP 91



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 18/53 (33%), Positives = 30/53 (56%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           +I ++D ND+ P F   +Y   + E  + GTTV  + A+D D   N +V ++I
Sbjct: 80  RITIIDVNDNRPYFLPTRYYVQLVENVAIGTTVTQVTASDLDSSLNGKVLFSI 132


>SB_32317| Best HMM Match : Cadherin (HMM E-Value=1.5e-28)
          Length = 331

 Score = 86.2 bits (204), Expect = 3e-16
 Identities = 66/200 (33%), Positives = 97/200 (48%), Gaps = 20/200 (10%)

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV-AQPLDFKQERR 436
           D    T  V++T  D + DN   ++    N   R S  ++ G  +I V A   D + + +
Sbjct: 26  DRKSATVRVSITVRDTN-DNSPQFQ--SQNYETRLSEAARPGSNVIQVSATDQDLEYKGK 82

Query: 437 YVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            +  ++  D           I + D N+  PVF  + Y A V E++P GT VL V A+D 
Sbjct: 83  VIYNITDGDEN--------LIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDR 134

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G N +ITY L++        + D  F IN  TG IT   ++DRE +  ++LTV A D 
Sbjct: 135 DQGANGKITYKLTN-------GNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQ 187

Query: 557 GVPSLSDT-TDVEISVVDVN 575
           G PS   T  +V I+V D N
Sbjct: 188 GEPSSRKTFAEVVITVKDEN 207



 Score = 82.2 bits (194), Expect = 5e-15
 Identities = 48/129 (37%), Positives = 75/129 (58%), Gaps = 4/129 (3%)

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
           +++D  +  I V DVNDN+PVF Q  Y A+++E++  GT V +V A+D D G NG+I Y+
Sbjct: 86  NITDGDENLIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYK 145

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST---VIVHIK 676
           L   ++++ +F I+  +G I     +DRE+V T  L   A D G P    T   V++ +K
Sbjct: 146 LTNGNKDD-AFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVK 204

Query: 677 IEDINDSPP 685
            E+I    P
Sbjct: 205 DENIEFLQP 213



 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 47/142 (33%), Positives = 80/142 (56%), Gaps = 7/142 (4%)

Query: 115 VLVKATDQASPVSDRLSSTATI---HVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPV 170
           + V ATDQ      ++    T    ++  +DD NDN P F++  Y   V E+ S T  PV
Sbjct: 68  IQVSATDQDLEYKGKVIYNITDGDENLIYVDDVNDNDPVFNQSKYAADVLEN-SPTGTPV 126

Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
           + ++ A+D D GAN  I Y +  GN    FSI++++G++++   +D E V ++ L ++A+
Sbjct: 127 L-RVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAE 185

Query: 231 DGGSP-SRSNTTQLLINIRDVN 251
           D G P SR    +++I ++D N
Sbjct: 186 DQGEPSSRKTFAEVVITVKDEN 207



 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 41/106 (38%), Positives = 58/106 (54%), Gaps = 4/106 (3%)

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
           LI + DVNDN P F  S +   V EN P G  ++RV A D D+G N ++TY +T+    G
Sbjct: 94  LIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTN----G 149

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
           N D   +I+  +G +  +G +DRE    + L V A D G+P    T
Sbjct: 150 NKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKT 195



 Score = 61.7 bits (143), Expect = 8e-09
 Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 2/97 (2%)

Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171
           R+ + + ATDQA+P+SDR S+T  + + + D NDN PQF  + Y   + E      N  +
Sbjct: 10  RFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSN--V 67

Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            ++ ATD D+     + Y I  G+  + +  D    D
Sbjct: 68  IQVSATDQDLEYKGKVIYNITDGDENLIYVDDVNDND 104



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 38/103 (36%), Positives = 55/103 (53%), Gaps = 7/103 (6%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F   +Y  ++ E+ P GTPV+ + A+D D+  + ++ Y++T GN    FSI   N  G I
Sbjct: 107 FNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSI--NNVTGEI 164

Query: 424 TVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDAN 463
           TVA  +D +    +VLTV A D G    R   A V I + D N
Sbjct: 165 TVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDEN 207



 Score = 58.4 bits (135), Expect = 8e-08
 Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 21/139 (15%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ PVF   +Y A V E + +GT VL + A+D+D G N ++ Y +     D  
Sbjct: 95  IYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKD-- 152

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            D F I+  +G +     +DRE V  + + V+A DQ  P S + 
Sbjct: 153 -----------------DAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRK- 194

Query: 131 SSTATIHVNIIDDNDNYPQ 149
            + A + + + D+N  + Q
Sbjct: 195 -TFAEVVITVKDENIEFLQ 212



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 35/91 (38%), Positives = 49/91 (53%), Gaps = 7/91 (7%)

Query: 547 YLLTVTARDGGVPSLSD----TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
           +LL +TA D   P +SD    T  V I+V D NDN P F+ Q Y   + E A  G++V Q
Sbjct: 11  FLLDITATDQATP-ISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQ 69

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVID 633
           V ATD D+   G++ Y +   D +E    +D
Sbjct: 70  VSATDQDLEYKGKVIYNI--TDGDENLIYVD 98



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 23/68 (33%), Positives = 37/68 (54%)

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           I ++D+ND+ PVF        + ENSP GT +  + A D D+G N  + Y +  G+  ++
Sbjct: 95  IYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDA 154

Query: 735 FSLETRQG 742
           FS+    G
Sbjct: 155 FSINNVTG 162



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 5/73 (6%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---- 62
           +   I V D ND+SP F+ Q YE  + E A  G+ V+ + ATDQD+    +V Y I    
Sbjct: 32  VRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGD 91

Query: 63  -ELVTADTLNPED 74
             L+  D +N  D
Sbjct: 92  ENLIYVDDVNDND 104



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 3/81 (3%)

Query: 223 YRLVIRAQDGGSP---SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
           + L I A D  +P    +S T ++ I +RD NDN+P+F +  ++  +SE    G ++++V
Sbjct: 11  FLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQV 70

Query: 280 QAYDADEGVNAELTYTMTDKD 300
            A D D     ++ Y +TD D
Sbjct: 71  SATDQDLEYKGKVIYNITDGD 91



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 5/84 (5%)

Query: 436 RYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           R++L ++ATD     S  +S T  V I + D N+ +P F++  Y   + E A  G+ V+ 
Sbjct: 10  RFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQ 69

Query: 491 VSATDSDVGINAQITYSLSSEISN 514
           VSATD D+    ++ Y+++    N
Sbjct: 70  VSATDQDLEYKGKVIYNITDGDEN 93



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 655 LKAVAIDGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
           L   A D  TP    +S+TV V I + D ND+ P F+S      +SE +  G+ + ++ A
Sbjct: 13  LDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSA 72

Query: 712 HDPDEGPNAVVHYSIKGGDDS 732
            D D      V Y+I  GD++
Sbjct: 73  TDQDLEYKGKVIYNITDGDEN 93



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNAN 838
           I V DVNDN PV    +   +  ++  P G P  RV A D D     K+ Y++ +GN  +
Sbjct: 95  IYVDDVNDNDPVFNQSKYAADVLENS-PTGTPVLRVHASDRDQGANGKITYKLTNGNKDD 153

Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
              +N  TG +T++  ++        + V   D
Sbjct: 154 AFSINNVTGEITVAGVIDREAVHTFVLTVQAED 186



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 331 KYQLLVTATDGGDP---PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           ++ L +TATD   P    +SAT                F    YE  L+E   PG+ V+ 
Sbjct: 10  RFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQ 69

Query: 388 LTATDADED--NRLHYEITGGN 407
           ++ATD D +   ++ Y IT G+
Sbjct: 70  VSATDQDLEYKGKVIYNITDGD 91


>SB_56860| Best HMM Match : Cadherin (HMM E-Value=4.4e-16)
          Length = 748

 Score = 81.8 bits (193), Expect = 7e-15
 Identities = 105/414 (25%), Positives = 167/414 (40%), Gaps = 35/414 (8%)

Query: 372 EVELAEDEPPGTPVVTLTATDADE------DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
           ++ + E+ P GT V  LTA D D+       +   +E+    + G F +        + V
Sbjct: 336 KLTVLENVPIGTEVGVLTANDGDDPWGTPASSNFSWELIS-TSDGHFKLIGSK----VVV 390

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
           A+ LD + +  + + +  +D G           +   N   P  +      SV EDA IG
Sbjct: 391 AKSLDHESKSIHKIVIKCSDFGHPVGITTATFMVNVLNKDEPPKQITLNPTSVAEDAGIG 450

Query: 486 TTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRE 542
                ++A D +   I   I  S +S +    +     +      T A  +     LD E
Sbjct: 451 ARAAGLTALDEEGDTIVFSIAPSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYE 510

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y LTV A     P         IS+++VN+  P   Q   + ++ E+A+ GT +  
Sbjct: 511 ARDLYSLTVMANSSTGPVFKSFL---ISIINVNE-APSDVQLTGSHSVGENAMAGTIIGS 566

Query: 603 VGATDADVGLNG-RIHY--ELDPKDREEGSFVIDPASGVIRTNKAL---DRESVATHDLK 656
              TD D  +   + HY        +  GS       G +   K +   D E      ++
Sbjct: 567 FMVTDPDNKVTQTQSHYCSAAAASAQSPGSSFFTVKGGAVLEVKGMPVIDYEKTRQLTIR 626

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY-ISENSPIGTTIGEIRAHDPD 715
               D GTP  S T    I ++D+N++P    S  LT   I ENSP GT +G +   DP 
Sbjct: 627 VTCTDDGTPKLSITKDFVIIVKDVNEAPT---SITLTNKSIPENSPTGTLVGTLTCEDP- 682

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           E PN    ++I  G     FS+    G+D    +    LDYE+  K  ++V++A
Sbjct: 683 ESPNDTCTFAIM-GPSGVPFSI----GADGKSFLVNGSLDYET-EKTIDVVVKA 730



 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 120/454 (26%), Positives = 183/454 (40%), Gaps = 34/454 (7%)

Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
           + IRA D GSP         + + +VND  P    +L + +V ENVPIG  +  + A D 
Sbjct: 300 VTIRATDDGSPQMWLEQTFKVKVLNVND--PPMNITLTKLTVLENVPIGTEVGVLTANDG 357

Query: 285 DE--GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
           D+  G  A   ++  +   T +    +        V  +  LD E+++ +++++  +D G
Sbjct: 358 DDPWGTPASSNFSW-ELISTSDGHFKLI----GSKVVVAKSLDHESKSIHKIVIKCSDFG 412

Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE 402
            P    TAT                     V  AED   G     LTA D + D  +   
Sbjct: 413 HPVGITTATFMVNVLNKDEPPKQITLNPTSV--AEDAGIGARAAGLTALDEEGDTIVFSI 470

Query: 403 ITGGN-TRGRFSI--TS--QNGRGLITVAQ-----PLDFKQERRYVLTVSATDSGGRSDT 452
               N T  +F I  TS   NG+     A       LD++    Y LTV A  S G    
Sbjct: 471 APSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYEARDLYSLTVMANSSTGPVFK 530

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
           + + I+I + N  AP       + SV E+A  GT +     TD D  +    ++  S+  
Sbjct: 531 SFL-ISIINVNE-APSDVQLTGSHSVGENAMAGTIIGSFMVTDPDNKVTQTQSHYCSAAA 588

Query: 513 SNEAVAHHDQQFVINPQTGAITTNK---LLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
           ++ A +     F +  + GA+   K   ++D E      + VT  D G P LS T D  I
Sbjct: 589 AS-AQSPGSSFFTV--KGGAVLEVKGMPVIDYEKTRQLTIRVTCTDDGTPKLSITKDFVI 645

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            V DV  NE      L   +I E++  GT V  +   D +   N    + +        S
Sbjct: 646 IVKDV--NEAPTSITLTNKSIPENSPTGTLVGTLTCEDPE-SPNDTCTFAIMGPSGVPFS 702

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
              D  S ++  N +LD E+  T D+   A D G
Sbjct: 703 IGADGKSFLV--NGSLDYETEKTIDVVVKATDRG 734



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 87/366 (23%), Positives = 144/366 (39%), Gaps = 20/366 (5%)

Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           SLD E  + + +++K +D   PV     +TAT  VN+++ ++   Q +    +V+ D  I
Sbjct: 393 SLDHESKSIHKIVIKCSDFGHPVG---ITTATFMVNVLNKDEPPKQITLNPTSVAEDAGI 449

Query: 164 SVTDNPVIAKIKATDADVGA-----NSAIRYAIIGGNT-QMQFSIDSLSGDVSLVKTLDY 217
                 + A  +  D  V +     NS +    IG  + ++     + + D+ +   LDY
Sbjct: 450 GARAAGLTALDEEGDTIVFSIAPSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDY 509

Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
           E    Y L + A     P   +    LI+I +VN+ AP         SV EN   G  I 
Sbjct: 510 EARDLYSLTVMANSSTGPVFKS---FLISIINVNE-APSDVQLTGSHSVGENAMAGTIIG 565

Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY-TSGQ--LDRETQAKYQL 334
                D D  V    ++  +    +           + G V    G   +D E   +  +
Sbjct: 566 SFMVTDPDNKVTQTQSHYCSAAAASAQSPGSSFFTVKGGAVLEVKGMPVIDYEKTRQLTI 625

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
            VT TD G P  S T                       +   E+ P GT V TLT  D +
Sbjct: 626 RVTCTDDGTPKLSITKDFVIIVKDVNEAPTSITLTNKSIP--ENSPTGTLVGTLTCEDPE 683

Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
             N        G +   FSI + +G+  + V   LD++ E+   + V ATD GG     +
Sbjct: 684 SPNDTCTFAIMGPSGVPFSIGA-DGKSFL-VNGSLDYETEKTIDVVVKATDRGGLYKEEI 741

Query: 455 VQINIT 460
           + ++++
Sbjct: 742 LTVSVS 747



 Score = 59.7 bits (138), Expect = 3e-08
 Identities = 92/403 (22%), Positives = 160/403 (39%), Gaps = 39/403 (9%)

Query: 115 VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174
           V ++ATD  SP   ++    T  V +++ ND  P  +     ++V E++ +     +  +
Sbjct: 300 VTIRATDDGSP---QMWLEQTFKVKVLNVND--PPMNITLTKLTVLENVPIGTE--VGVL 352

Query: 175 KATDAD----VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
            A D D      A+S   + +I   +   F +  +   V + K+LD+E    +++VI+  
Sbjct: 353 TANDGDDPWGTPASSNFSWELIS-TSDGHFKL--IGSKVVVAKSLDHESKSIHKIVIKCS 409

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           D G P    T   ++N+  +N + P    +L   SV+E+  IG     + A D +EG   
Sbjct: 410 DFGHPVGITTATFMVNV--LNKDEPPKQITLNPTSVAEDAGIGARAAGLTALD-EEGDTI 466

Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYT-------SGQLDRETQAKYQLLVTATDGGD 343
             +   +D       ++  T    +G   T        G+LD E +  Y L V A     
Sbjct: 467 VFSIAPSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYEARDLYSLTVMANSSTG 526

Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLH 400
           P   +                  + G + V   E+   GT + +   TD D      + H
Sbjct: 527 PVFKSFLISIINVNEAPSDVQ--LTGSHSV--GENAMAGTIIGSFMVTDPDNKVTQTQSH 582

Query: 401 Y---EITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSG--GRSDTAM 454
           Y         + G    T + G  L     P +D+++ R+  + V+ TD G    S T  
Sbjct: 583 YCSAAAASAQSPGSSFFTVKGGAVLEVKGMPVIDYEKTRQLTIRVTCTDDGTPKLSITKD 642

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
             I + D N  AP         S+ E++P GT V  ++  D +
Sbjct: 643 FVIIVKDVNE-APTSITLT-NKSIPENSPTGTLVGTLTCEDPE 683



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 66/251 (26%), Positives = 102/251 (40%), Gaps = 24/251 (9%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           L+ +  LD E    Y++ V A     PV        +  ++II+ N+  P   + T + S
Sbjct: 501 LMVKGKLDYEARDLYSLTVMANSSTGPVFK------SFLISIINVNEA-PSDVQLTGSHS 553

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL----SGDVSLVK- 213
           V E+       +I     TD D        +         Q    S      G V  VK 
Sbjct: 554 VGENAMA--GTIIGSFMVTDPDNKVTQTQSHYCSAAAASAQSPGSSFFTVKGGAVLEVKG 611

Query: 214 --TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
              +DYE+ R   + +   D G+P  S T   +I ++DVN+ AP   T L  +S+ EN P
Sbjct: 612 MPVIDYEKTRQLTIRVTCTDDGTPKLSITKDFVIIVKDVNE-APTSIT-LTNKSIPENSP 669

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
            G ++V     +  E  N   T+ +      G   +P +I         +G LD ET+  
Sbjct: 670 TG-TLVGTLTCEDPESPNDTCTFAI-----MGPSGVPFSIGADGKSFLVNGSLDYETEKT 723

Query: 332 YQLLVTATDGG 342
             ++V ATD G
Sbjct: 724 IDVVVKATDRG 734



 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 62/248 (25%), Positives = 107/248 (43%), Gaps = 23/248 (9%)

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           +T+ A D G P +      ++ V++VND  P     L    ++E+  +GT V  + A D 
Sbjct: 300 VTIRATDDGSPQMWLEQTFKVKVLNVND--PPMNITLTKLTVLENVPIGTEVGVLTANDG 357

Query: 609 D--VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D   G     ++  +     +G F +  +  V+   K+LD ES + H +     D G P 
Sbjct: 358 DDPWGTPASSNFSWELISTSDGHFKLIGSKVVVA--KSLDHESKSIHKIVIKCSDFGHPV 415

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             +T    + +  +N   P  +       ++E++ IG     + A D +EG   V  +SI
Sbjct: 416 GITTATFMVNV--LNKDEPPKQITLNPTSVAEDAGIGARAAGLTALD-EEGDTIV--FSI 470

Query: 727 KGGDDS---------NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--PLW 775
              D+S          S  L  +Q +  A+L+    LDYE+ R  Y L + A S   P++
Sbjct: 471 APSDNSTLEKFEIGPTSCRLNGKQSTCAADLMVKGKLDYEA-RDLYSLTVMANSSTGPVF 529

Query: 776 NDVRVEIL 783
               + I+
Sbjct: 530 KSFLISII 537


>SB_10800| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 943

 Score = 76.2 bits (179), Expect = 4e-13
 Identities = 72/287 (25%), Positives = 124/287 (43%), Gaps = 16/287 (5%)

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF---ENAPYTASVFED 481
           +A+ L+  + +   LT+ A D+  R  T  V+ +I + N + P F   E+ PY  +V E+
Sbjct: 26  IARALNSDENKFCELTIIAKDAEKRVTTTRVRFDIINMNKHRPQFNKPESEPYICAVTEN 85

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA-ITTNKLLD 540
             +   +  ++ TD D G   +I      E++   +     +F +N      +   K  D
Sbjct: 86  TRVVRILPKINVTDQDRGEAGKIK---RIEVAESGIPF---KFNVNDDGSVEVVALKDFD 139

Query: 541 RETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            E  SGYL  + A DGG PS  S    V+  +VDVN+  P F+     A ++E       
Sbjct: 140 AEKESGYLFDIKAFDGGDPSKTSKPVQVDCRIVDVNEFPPTFESNNVVA-VVERGKTYKK 198

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           + Q+ ATD D+G    +  +   +  +    + +   GV+  +K L  ++      +  A
Sbjct: 199 ILQLTATDKDIGKENGVVCKYVVRTADVPFKITN--DGVLYLDKPLGSDAPEYCAFEVAA 256

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           +D G       V V + I+D     P +  D L   +S    +G  I
Sbjct: 257 VDCGGKISVENVNVRVDIKD--SCKPGYNMDQLLGKVSIPQCVGKAI 301



 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 57/198 (28%), Positives = 94/198 (47%), Gaps = 17/198 (8%)

Query: 97  GALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE--- 152
           G  + RA + D  K    T++ K  ++      R+++T  +  +II+ N + PQF++   
Sbjct: 23  GKKIARALNSDENKFCELTIIAKDAEK------RVTTTR-VRFDIINMNKHRPQFNKPES 75

Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI-RYAIIGGNTQMQFSI-DSLSGDVS 210
           + Y  +V E+  V    ++ KI  TD D G    I R  +       +F++ D  S +V 
Sbjct: 76  EPYICAVTENTRVVR--ILPKINVTDQDRGEAGKIKRIEVAESGIPFKFNVNDDGSVEVV 133

Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            +K  D E+   Y   I+A DGG PS+ S   Q+   I DVN+  P F ++    +V E 
Sbjct: 134 ALKDFDAEKESGYLFDIKAFDGGDPSKTSKPVQVDCRIVDVNEFPPTFESNNV-VAVVER 192

Query: 270 VPIGYSIVRVQAYDADEG 287
                 I+++ A D D G
Sbjct: 193 GKTYKKILQLTATDKDIG 210



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 53/270 (19%), Positives = 106/270 (39%), Gaps = 14/270 (5%)

Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
           ++S    + + L+ ++ +   L I A+D  +  R  TT++  +I ++N + P+F     +
Sbjct: 19  AVSEGKKIARALNSDENKFCELTIIAKD--AEKRVTTTRVRFDIINMNKHRPQFNKPESE 76

Query: 264 E---SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI-DPRSGWVY 319
               +V+EN  +   + ++   D D G   ++      +     +     + D  S  V 
Sbjct: 77  PYICAVTENTRVVRILPKINVTDQDRGEAGKIKRIEVAES---GIPFKFNVNDDGSVEVV 133

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
                D E ++ Y   + A DGGDP +++                        V + E  
Sbjct: 134 ALKDFDAEKESGYLFDIKAFDGGDPSKTSKPVQVDCRIVDVNEFPPTFESNNVVAVVERG 193

Query: 380 PPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
                ++ LTATD D  ++N +  +         F IT+    G++ + +PL        
Sbjct: 194 KTYKKILQLTATDKDIGKENGVVCKYVVRTADVPFKITND---GVLYLDKPLGSDAPEYC 250

Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAP 467
              V+A D GG+     V + +   ++  P
Sbjct: 251 AFEVAAVDCGGKISVENVNVRVDIKDSCKP 280



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
           ++D N+  P FE     A V  G +    +L L ATD+DIGK   V     + TAD
Sbjct: 171 IVDVNEFPPTFESNNVVAVVERGKTY-KKILQLTATDKDIGKENGVVCKYVVRTAD 225


>SB_45116| Best HMM Match : EGF (HMM E-Value=0)
          Length = 2023

 Score = 74.5 bits (175), Expect = 1e-12
 Identities = 82/292 (28%), Positives = 118/292 (40%), Gaps = 36/292 (12%)

Query: 1292 HKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            H  ID+   VAD G L    ++   CSS PC NGA CSDL + Y C C  G  G+ C   
Sbjct: 1276 HPNIDMEKGVADQGNLIADIDE---CSSNPCLNGATCSDLLNNYTCTCASGFQGERCEQK 1332

Query: 1352 TGPPWRFGGDGMLSF----NPLLRPIQLPWLNALSIRTRQRDAFVMS---------IQL- 1397
            T     F G    +F     PL++  +       S+    ++  +MS         IQ+ 
Sbjct: 1333 TSCQLAFYGRSTSNFAAVTMPLIKFEEFTICAWYSLAQEWQENVIMSYVTSNNRSQIQVA 1392

Query: 1398 --KSGLLHYSYNGETMYLPMAT--LSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLAN 1453
              K G L    N  T+ +P++   LS   WH + ++W  TD   TV YG +T       +
Sbjct: 1393 IRKDGKLELMVNWNTVTVPVSANFLSIIGWHFLCVQW-KTDGKATV-YGDKTSFGDDTFD 1450

Query: 1454 KIQGQYI---GKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDG 1510
            K++   I   GK+++G           D   F G +  V I    S L+   +       
Sbjct: 1451 KLKNLGIVGGGKVVLGASQRCLEGCFDDRLTFHGNVSQVNIW--NSKLSSGDIELVFVGS 1508

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARC 1562
            C S      ++  P    V  W +   +   G VG  C  +C  GP GA  C
Sbjct: 1509 CLSYG----AVDSP----VLGWKTIQASPLNGAVGGVCPVSCPFGPTGALSC 1552



 Score = 69.7 bits (163), Expect = 3e-11
 Identities = 63/209 (30%), Positives = 77/209 (36%), Gaps = 29/209 (13%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQT 1567
            C+   +C  + C     CV   D  TCTCEAG  G  C   ++ C+ GPC       D+ 
Sbjct: 160  CEEIKECTSAPCQNGGSCVDRRDGYTCTCEAGYNGINCEIEINECDSGPCNNGGTCTDRV 219

Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNK-ENG- 1624
              GY C C  GYT T   C E   +EC       G  C     D+  GY+  C    NG 
Sbjct: 220  -NGYECVCNAGYTGTR--C-EIDIDECASNPCINGGTC----TDMVNGYNCTCPPGYNGT 271

Query: 1625 KC-----HCKENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
             C      C  N     GT   L     C C   G   ++CE    +C   P V G  C 
Sbjct: 272  TCEIDINECASNPCLNGGTCNDLVNGYNCNC-PPGYNGTTCEIDINECASNPCVNGGTCA 330

Query: 1676 ACANAYAEVTPNSGCEVVYDGCPRSFAGG 1704
               N +     N  C   Y G     A G
Sbjct: 331  DLVNGF-----NCTCPPGYKGTKCEIATG 354



 Score = 56.0 bits (129), Expect = 4e-07
 Identities = 56/212 (26%), Positives = 78/212 (36%), Gaps = 39/212 (18%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS---------ACELGPCGAARCVPDQ 1566
            +C  + C     C    +S +CTC +G  G QC +         A ++  C +  C+   
Sbjct: 1024 ECDSNPCANGGTCADQVNSFSCTCVSGYTGLQCKTGTVLRYNEKAVDINECASNPCLNGG 1083

Query: 1567 T----PKGYSCACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620
            T      GY+C C+PGY  TT      E    +C  G       G C  D+  G++  C 
Sbjct: 1084 TCNDLVNGYNCKCQPGYNGTTCEIDINECASNQCVNG-------GTCT-DLVNGFNCTCP 1135

Query: 1621 K-ENG-KC-----HCKENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGV 1669
               NG KC      C+ N     GT         C C  +G     CE    +C   P V
Sbjct: 1136 PGYNGTKCEININECENNPCVNGGTCADQVNSFSCTC-VSGYTGLKCETDINECASNPCV 1194

Query: 1670 IGRACDACANAYAEVTP----NSGCEVVYDGC 1697
             G  C    N +    P     + CE+  D C
Sbjct: 1195 NGGTCTDLVNGFHCTCPPGYNGTKCEIDIDEC 1226



 Score = 51.6 bits (118), Expect = 9e-06
 Identities = 51/177 (28%), Positives = 63/177 (35%), Gaps = 28/177 (15%)

Query: 1534 SSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESG 1590
            +S C C AG  G  C  +  C   PC     CV  +   GY+C CE GY      C E  
Sbjct: 146  TSRCRCVAGYTGEHCEEIKECTSAPCQNGGSCVDRR--DGYTCTCEAGY--NGINC-EIE 200

Query: 1591 KEECPGGWWGGSACGPCACDVTRGYHPHCNK--ENGKC-----HCKENHYKPEGTAECL- 1642
              EC  G       G C  D   GY   CN      +C      C  N     GT   + 
Sbjct: 201  INECDSGPCNNG--GTCT-DRVNGYECVCNAGYTGTRCEIDIDECASNPCINGGTCTDMV 257

Query: 1643 ---PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDG 1696
                C C   G   ++CE    +C   P + G  C+   N Y     N  C   Y+G
Sbjct: 258  NGYNCTC-PPGYNGTTCEIDINECASNPCLNGGTCNDLVNGY-----NCNCPPGYNG 308



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 17/37 (45%), Positives = 22/37 (59%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E+   C+SAPC NG  C D  D Y C C+ G+ G +C
Sbjct: 161  EEIKECTSAPCQNGGSCVDRRDGYTCTCEAGYNGINC 197



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            NGT   C    + C+S PC NG  C+DL + + C C  G+ G  C  +TG
Sbjct: 307  NGTT--CEIDINECASNPCVNGGTCADLVNGFNCTCPPGYKGTKCEIATG 354



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 2/45 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            NGT   C    + C+S PC NG  C+DL + Y C+C  G+ G  C
Sbjct: 269  NGTT--CEIDINECASNPCLNGGTCNDLVNGYNCNCPPGYNGTTC 311



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 2/49 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            NGT   C    + C S PC NG  C+D  +++ C C  G+TG  C   T
Sbjct: 1014 NGTK--CEIDINECDSNPCANGGTCADQVNSFSCTCVSGYTGLQCKTGT 1060



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 15/34 (44%), Positives = 21/34 (61%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C+S PC NG  C+DL + Y C C+ G+ G  C
Sbjct: 1072 NECASNPCLNGGTCNDLVNGYNCKCQPGYNGTTC 1105



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  + + C S PC NG  C+D  + Y C C  G+TG  C
Sbjct: 197  CEIEINECDSGPCNNGGTCTDRVNGYECVCNAGYTGTRC 235



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S PC NG  C+DL + + C C  G+ G  C
Sbjct: 1181 CETDINECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKC 1219



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC NG  C+D+ + Y C C  G+ G  C
Sbjct: 235  CEIDIDECASNPCINGGTCTDMVNGYNCTCPPGYNGTTC 273



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 2/45 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            NGT   C    + C + PC NG  C+D  +++ C C  G+TG  C
Sbjct: 1139 NGTK--CEININECENNPCVNGGTCADQVNSFSCTCVSGYTGLKC 1181



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 14/34 (41%), Positives = 20/34 (58%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C+S PC NG  C+DL + + C C  G+ G  C
Sbjct: 985  NECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKC 1018



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            NGT   C    + C+S  C NG  C+DL + + C C  G+ G  C
Sbjct: 1101 NGTT--CEIDINECASNQCVNGGTCTDLVNGFNCTCPPGYNGTKC 1143



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            NGT   C      C+S PC NG  C++L + + C C  G+ G  C
Sbjct: 1215 NGTK--CEIDIDECASNPCINGGTCTELVNGFKCTCVPGYNGTRC 1257



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 10/64 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC C  G+ G+NCE  + +       D   C +G  C  R  G      C  +A YT  
Sbjct: 184  YTCTCEAGYNGINCEIEINEC------DSGPCNNGGTCTDRVNG----YECVCNAGYTGT 233

Query: 1102 VCEL 1105
             CE+
Sbjct: 234  RCEI 237



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 40/168 (23%), Positives = 58/168 (34%), Gaps = 21/168 (12%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C     C    +   CTC  G  G +C   +  C   PC     C   +   G+
Sbjct: 1187 ECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKCEIDIDECASNPCINGGTCT--ELVNGF 1244

Query: 1572 SCACEPGYTLTTSGCIESGK--EECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
             C C PGY  T    +   +  ++CP  + G         D+ +G     N       C 
Sbjct: 1245 KCTCVPGYNGTRCEIVLRPRPPKDCPSRFEGHP-----NIDMEKGVADQGNLIADIDECS 1299

Query: 1630 ENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRA 1673
             N      T   L     C C A+G +   CE  T    C+    GR+
Sbjct: 1300 SNPCLNGATCSDLLNNYTCTC-ASGFQGERCEQKTS---CQLAFYGRS 1343



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 11/62 (17%)

Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103
            C+C  G+TG +CE I    S         C++G  CV RR+G      C+ +A Y    C
Sbjct: 149  CRCVAGYTGEHCEEIKECTSAP-------CQNGGSCVDRRDG----YTCTCEAGYNGINC 197

Query: 1104 EL 1105
            E+
Sbjct: 198  EI 199



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 40/163 (24%), Positives = 50/163 (30%), Gaps = 14/163 (8%)

Query: 1549 VSACELGPCGAARCVPDQTPKGYSCACEPGY--TLTTSGCIESGKEECPGGWWGGSACGP 1606
            ++ C   PC       D    G+ C C PGY  T       E     C  G         
Sbjct: 984  INECASNPCVNGGTCTDLV-NGFHCTCPPGYNGTKCEIDINECDSNPCANGGTCADQVNS 1042

Query: 1607 CACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCR 1666
             +C    GY     K        E   K     EC    C   G+ N         C C+
Sbjct: 1043 FSCTCVSGYTGLQCKTGTVLRYNE---KAVDINECASNPCLNGGTCNDLVNGY--NCKCQ 1097

Query: 1667 PGVIGRACDACANAYA-EVTPNSG-CEVVYDG----CPRSFAG 1703
            PG  G  C+   N  A     N G C  + +G    CP  + G
Sbjct: 1098 PGYNGTTCEIDINECASNQCVNGGTCTDLVNGFNCTCPPGYNG 1140



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 13/35 (37%), Positives = 20/35 (57%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073
            V SF+C C  G+TG+ CET + + +     +G  C
Sbjct: 1165 VNSFSCTCVSGYTGLKCETDINECASNPCVNGGTC 1199



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQG--CSIDA 1096
            V SF+C C  G+TG+ C+T       E   D + C S + C+       L  G  C    
Sbjct: 1040 VNSFSCTCVSGYTGLQCKTGTVLRYNEKAVDINECAS-NPCLNGGTCNDLVNGYNCKCQP 1098

Query: 1097 AYTTAVCEL 1105
             Y    CE+
Sbjct: 1099 GYNGTTCEI 1107



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  F C CP G+ G  CE  + +  CE     + C +G  C  +    +    C+  + Y
Sbjct: 1127 VNGFNCTCPPGYNGTKCEININE--CE----NNPCVNGGTCADQ----VNSFSCTCVSGY 1176

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 1177 TGLKCE 1182


>SB_54100| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 3287

 Score = 74.1 bits (174), Expect = 1e-12
 Identities = 81/339 (23%), Positives = 128/339 (37%), Gaps = 46/339 (13%)

Query: 1281 FVGCISDFYIDHKFIDLNSYVADNGTLA----GCPEKRSRCSSAPCYNGAECSDLWDTYI 1336
            F GC+ D +++    +  S V  + +      GC  K + C +  C NG  C   W  + 
Sbjct: 1427 FNGCVRDIFVNSVEQNFGSAVRSSSSFTLPKPGC-RKETNCHAESCANGGTCVATWTGFQ 1485

Query: 1337 CDCKEGHTGKDCADSTGPP----------------WRFGGDGMLSFNPLLRPIQLPWLNA 1380
            C C     G  C + T                   WRFG  G L      R I L  L  
Sbjct: 1486 CRCLAEFNGTRCENGTATTFLANTSSIQLGLNTTEWRFGQSGSLRVRTS-RAIGL--LLY 1542

Query: 1381 LSIRTRQRDAFVMSIQLKSGLLHYSYN---GETMYLPMATLSDGAWHRIEIKWLGTDISV 1437
               +    +   + + L SG +  + +   G    +   T++DG WH I        + +
Sbjct: 1543 AGWKPSGPNTEYLMVDLVSGKVRLTADLGSGPGSVINPMTVNDGDWHHITWSRQYKRLIL 1602

Query: 1438 TVD---YGLRTVLMPMLANKIQGQYIGKILIGGLD--TTAGLLASDVGFFEGCIQD---- 1488
            +VD     + T     + +    + I  + IGG     ++    S +  F+GC++D    
Sbjct: 1603 SVDDVTMEMSTQGEQSVLDVADSEII-YVHIGGFPYLKSSATGLSTITSFQGCLKDLTFH 1661

Query: 1489 ---VRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG 1545
               V   T  S     ++  NV  GC S   C  + C  YS C  +  +  CTC +G  G
Sbjct: 1662 YRYVHFLTPFSQQGLASILRNVTTGCHSIGPCSSNPCQGYSTCENAGGAYNCTCLSGWTG 1721

Query: 1546 PQC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
             +C   +  C +  C   A CV +    G+ C C  G+T
Sbjct: 1722 DKCDVRIPDCIIANCSNGATCVNES--NGFRCQCAVGFT 1758



 Score = 72.1 bits (169), Expect = 6e-12
 Identities = 86/314 (27%), Positives = 123/314 (39%), Gaps = 46/314 (14%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            F C C  G+TG+ C   + + +       S C +G  C     G      C+    YT +
Sbjct: 967  FICDCKAGYTGLACTINIDECA------SSPCFNGGSCRDDVNG----YTCTCAPGYTGS 1016

Query: 1102 VCE-LRARSFPVSSFLTFPGLKRR---HRIHLKLKFATQTTSGLLLYNG--RYNERHDFL 1155
             CE L   SF   S++     + R    R  ++  F T  + GLLLY G  R  E  D +
Sbjct: 1017 RCEMLDEVSFRRGSYMPVYWYRDRPLPARARVEFLFRTSLSDGLLLYQGADRSLEHPDHV 1076

Query: 1156 ALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDC 1215
            ALEL+     RG    LR S + G      T+  ++ D ++H V +   N   T+ +   
Sbjct: 1077 ALELL-----RG---SLRLSLNTGFDTQVDTIGRDLNDSTYHQVTLVLENNRATVEVS-- 1126

Query: 1216 DKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQ 1275
                   G+ D G K +       V  A   + T        L G  Q G  P I     
Sbjct: 1127 ------GGSCDAGCKGSVTTQLSAVF-AYSGLAT--------LGGLAQTG--PVIRDQI- 1168

Query: 1276 VKNKDFVGCISDFYIDHKFIDLNSYVADN-GTLAGCPEKRSRCSSAPCYNGAECSDLWDT 1334
              + +FVGCI DF ++     L  ++        GC  +   C +  C NG  C D+W  
Sbjct: 1169 ATDGNFVGCIKDFKLNLISDYLRDFIPHAVHVTPGC-ARTDVCKNHKCTNGGACVDMWSE 1227

Query: 1335 YICDCKEGHTGKDC 1348
            Y C C  G  G  C
Sbjct: 1228 YRCQCPTGFAGTFC 1241



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 65/266 (24%), Positives = 98/266 (36%), Gaps = 31/266 (11%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369
            C      C+S+PC+NG  C D  + Y C C  G+TG  C       +R  G  M  +   
Sbjct: 980  CTINIDECASSPCFNGGSCRDDVNGYTCTCAPGYTGSRCEMLDEVSFR-RGSYMPVYWYR 1038

Query: 1370 LRPIQLPWLNALSIRTRQRDAFVM--------------SIQLKSGLLHYSYNG--ETMYL 1413
             RP+          RT   D  ++              +++L  G L  S N   +T   
Sbjct: 1039 DRPLPARARVEFLFRTSLSDGLLLYQGADRSLEHPDHVALELLRGSLRLSLNTGFDTQVD 1098

Query: 1414 PMA-TLSDGAWHRIEIKWLGTDISVTV-----DYGLRTVLMPMLANKIQGQYIGKILIGG 1467
             +   L+D  +H++ +       +V V     D G +  +   L+      Y G   +GG
Sbjct: 1099 TIGRDLNDSTYHQVTLVLENNRATVEVSGGSCDAGCKGSVTTQLSAVF--AYSGLATLGG 1156

Query: 1468 LDTTAGLLASDV---GFFEGCIQDVRIGTAQSLLNRPTVRE--NVRDGCQSRADCMLSIC 1522
            L  T  ++   +   G F GCI+D ++      L R  +    +V  GC     C    C
Sbjct: 1157 LAQTGPVIRDQIATDGNFVGCIKDFKLNLISDYL-RDFIPHAVHVTPGCARTDVCKNHKC 1215

Query: 1523 PPYSKCVTSWDSSTCTCEAGRVGPQC 1548
                 CV  W    C C  G  G  C
Sbjct: 1216 TNGGACVDMWSEYRCQCPTGFAGTFC 1241



 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 11/166 (6%)

Query: 1392 VMSIQLKSGLLHYSYN----GETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVL 1447
            V+ + L++G LH +Y       T       LS+G WHR+EI      I++ V+  +  + 
Sbjct: 1334 VLGLALRNGRLHAAYVMGFFQSTSVEIGRDLSNGNWHRVEISVTFGYITIKVNSDVTILR 1393

Query: 1448 MPMLANKIQGQ-YIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQ----SLLNRPT 1502
             P     +Q + Y+G +L    +    L  S    F GC++D+ + + +    S +   +
Sbjct: 1394 PPSTVPNLQTKVYMGNLLSSMTELNVELSRSIT--FNGCVRDIFVNSVEQNFGSAVRSSS 1451

Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548
                 + GC+   +C    C     CV +W    C C A   G +C
Sbjct: 1452 SFTLPKPGCRKETNCHAESCANGGTCVATWTGFQCRCLAEFNGTRC 1497



 Score = 54.8 bits (126), Expect = 9e-07
 Identities = 51/183 (27%), Positives = 64/183 (34%), Gaps = 17/183 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C +  D C    C   + CV+S    TC C  G  G  C   +  C   PC       D+
Sbjct: 2163 CNTLIDFCYSDPCAYGATCVSSLADYTCACVPGYTGRNCTTNIDDCLSAPCKNGATCEDK 2222

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGYHPHCNKE 1622
               GY C C  G+  T   C E+  E  P     G+ C       AC    GY    N  
Sbjct: 2223 V-NGYLCKCPDGFHST--NCSENINECDPNPCLNGATCLDKIADYACVCPSGY-SGINCS 2278

Query: 1623 NGKCHCKENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678
                 C+ N  +  GT   L     C C A G    +C      C  RP   G  C+   
Sbjct: 2279 VNVNDCRTNPCENGGTCIDLIGGYACTC-APGFTGVNCSVNIDDCASRPCKNGATCNDGV 2337

Query: 1679 NAY 1681
            N+Y
Sbjct: 2338 NSY 2340



 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 48/177 (27%), Positives = 60/177 (33%), Gaps = 12/177 (6%)

Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACE 1576
            S C  +  C+   +S TC C  G  G  C   V+ C   PC       D    GYSCAC 
Sbjct: 672  SPCSEHGACIDGVNSYTCACNLGYTGSTCNVTVNDCISNPCIHGATCHDGL-LGYSCACA 730

Query: 1577 PGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKC---HCKE 1630
             G+T         +     C              C    GY  + C+    +C    C  
Sbjct: 731  VGFTGINCEININDCASNPCAAYQRCIDRIDSYTCACPLGYTGNACDVNIDECASQPCLN 790

Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPN 1687
            N    +G      C C  AG E   CE  T +C   P   G  C    N +  V PN
Sbjct: 791  NGTCQDGRGN-FSCVC-PAGFEGLRCENQTNECASSPCFNGGTCHDLLNRFECVCPN 845



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 50/188 (26%), Positives = 64/188 (34%), Gaps = 26/188 (13%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG- 1570
            DC  + C  Y +C+   DS TC C  G  G  C   +  C   PC     C   Q  +G 
Sbjct: 744  DCASNPCAAYQRCIDRIDSYTCACPLGYTGNACDVNIDECASQPCLNNGTC---QDGRGN 800

Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
            +SC C  G+      C E+   EC     + G  C     D+   +   C        C+
Sbjct: 801  FSCVCPAGF--EGLRC-ENQTNECASSPCFNGGTCH----DLLNRFECVCPNGFLGRQCE 853

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689
             N        ECL   C   G+          QC C  G  G    AC   Y        
Sbjct: 854  AN------VVECLSDPCLNNGTCVEKIGVVGYQCVCPDGFAGDFSCACPVGYT----GKL 903

Query: 1690 CEVVYDGC 1697
            CE+  D C
Sbjct: 904  CEIDIDDC 911



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 48/176 (27%), Positives = 60/176 (34%), Gaps = 14/176 (7%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  + C   + CV   +  +C C AG  G  C   +  C   PC       D+    Y 
Sbjct: 2601 DCATNPCGNGATCVDEINKYSCLCPAGFSGGNCQTNIDECASRPCANVGSCIDRI-NSYE 2659

Query: 1573 CACEPGYTLTTS--GCIESGKEEC-PGGWWGGSACG-PCACDVTRGY-HPHCNKENGKCH 1627
            C C PGYT         E   + C  GG       G  CAC V  GY   +C+ E  +C 
Sbjct: 2660 CTCVPGYTGRNCQVDIDECESKPCVNGGTCIDRVAGYSCACAV--GYTDQNCSVEIDECA 2717

Query: 1628 CKE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
                 N            C C   G    +CE    +C   P   G  C    N Y
Sbjct: 2718 SNPCLNGATCTDRLGGYACSC-IPGFTGKNCETDLDECLSNPCGNGATCRHLVNNY 2772



 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 50/200 (25%), Positives = 74/200 (37%), Gaps = 23/200 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C     C+   +  TC C+ G +G +C   ++ C   PC   A+C   Q   G+
Sbjct: 589  ECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRCHAFINKCLFNPCKNGAKCQTLQ-DGGH 647

Query: 1572 SCACEPGY--TLTTSGCIESGKEECPGGWWGGSACG----PCACDVTRGY-HPHCNKENG 1624
             C CE G+  +L      E  + + P    G    G     CAC++  GY    CN    
Sbjct: 648  RCLCEKGFKGSLCEVNVNECNETQSPCSEHGACIDGVNSYTCACNL--GYTGSTCNVTVN 705

Query: 1625 KC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
             C    C       +G      C C A G    +CE     C   P    + C    ++Y
Sbjct: 706  DCISNPCIHGATCHDGLLG-YSCAC-AVGFTGINCEININDCASNPCAAYQRCIDRIDSY 763

Query: 1682 AEVTP----NSGCEVVYDGC 1697
                P     + C+V  D C
Sbjct: 764  TCACPLGYTGNACDVNIDEC 783



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 47/163 (28%), Positives = 62/163 (38%), Gaps = 20/163 (12%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  S C   + CV   +  +CTC  G     C   +  C   PC   A CV D   K Y
Sbjct: 2525 DCATSPCRNGATCVDGINKYSCTCPIGFTDQTCSTNIDDCATNPCRNGATCV-DGINK-Y 2582

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            SC C  G+T  T  C  +  ++C     G  A   C  ++ + Y   C       +C+ N
Sbjct: 2583 SCTCPIGFTDQT--C-STNIDDCATNPCGNGA--TCVDEINK-YSCLCPAGFSGGNCQTN 2636

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
                    EC    C   GS      +   +C C PG  GR C
Sbjct: 2637 ------IDECASRPCANVGSCIDRINSY--ECTCVPGYTGRNC 2671



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 45/185 (24%), Positives = 68/185 (36%), Gaps = 33/185 (17%)

Query: 1509 DGCQSRA-DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            D C  R  DC+++ C   + CV   +   C C  G  G  C   ++ C   PC   A C+
Sbjct: 1722 DKCDVRIPDCIIANCSNGATCVNESNGFRCQCAVGFTGKFCEAIINPCAPSPCKNGATCI 1781

Query: 1564 PDQTPKGYSCACEPGYT----------LTTSGCIESGK-----EE----CPGGWWGGSAC 1604
             +   K Y C C   +T           ++S C+  G      E+    CPGG++G    
Sbjct: 1782 REAHGK-YRCQCALDFTGFNCEIRVNNCSSSPCLHGGTCIDGFEDYNCTCPGGYYGKQ-- 1838

Query: 1605 GPCACDVTRGYHPHCNKENGKCHCKENHYKPE--GTAECLPCQCYAAGSENSSCEAATGQ 1662
                C+       H  K N  C+ +++ Y     G      C    AG   + C     +
Sbjct: 1839 ----CETVDTCFAHACKNNATCNRRDSDYTCTCVGNFAGELCDSCTAGYTGADCNTPMKK 1894

Query: 1663 CHCRP 1667
            C   P
Sbjct: 1895 CLTSP 1899



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 18/39 (46%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D    Y C C  G TGK+C
Sbjct: 2709 CSVEIDECASNPCLNGATCTDRLGGYACSCIPGFTGKNC 2747



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  + + C+S+PC+NG  C DL + + C C  G  G+ C
Sbjct: 814  CENQTNECASSPCFNGGTCHDLLNRFECVCPNGFLGRQC 852



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 48/191 (25%), Positives = 68/191 (35%), Gaps = 25/191 (13%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQ 1566
            C+ R + C  S C     C+  ++   CTC  G  G QC  V  C    C   A C  ++
Sbjct: 1801 CEIRVNNCSSSPCLHGGTCIDGFEDYNCTCPGGYYGKQCETVDTCFAHACKNNATC--NR 1858

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
                Y+C C   +      C     + C  G+ G      C   + +     C K NG C
Sbjct: 1859 RDSDYTCTCVGNF--AGELC-----DSCTAGYTGAD----CNTPMKKCLTSPC-KNNGTC 1906

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAEVT 1685
            +          T  C+      AG    SCE    +C   P   G  C D+ ++A   V 
Sbjct: 1907 YHDAQQPWTNRTCSCI------AGFTGMSCETDVDECLSSPCANGGTCSDSTSSASHFVG 1960

Query: 1686 PNSGCEVVYDG 1696
                C   Y+G
Sbjct: 1961 FICACVQGYEG 1971



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 18/44 (40%), Positives = 25/44 (56%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            T   C      C+S PC NGA C+D  ++Y C C  G +GK+C+
Sbjct: 2311 TGVNCSVNIDDCASRPCKNGATCNDGVNSYTCSCAAGFSGKNCS 2354



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 18/39 (46%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C +APC NGA C      +ICDCK G+TG  C
Sbjct: 942  CENLVTNCDTAPCQNGATCKIGAKGFICDCKAGYTGLAC 980



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 9/68 (13%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            F CQC  GFTG  CE I+   +       S C++G+ C+    G   CQ C++D  +T  
Sbjct: 1749 FRCQCAVGFTGKFCEAIINPCA------PSPCKNGATCIREAHGKYRCQ-CALD--FTGF 1799

Query: 1102 VCELRARS 1109
             CE+R  +
Sbjct: 1800 NCEIRVNN 1807



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 18/41 (43%), Positives = 21/41 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C      C S PC NGA C  L + Y C C  G TG++C D
Sbjct: 2747 CETDLDECLSNPCGNGATCRHLVNNYTCICAVGFTGRNCLD 2787



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 46/179 (25%), Positives = 61/179 (34%), Gaps = 21/179 (11%)

Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSS---TCTCEAGRVGPQC---VSACELGP 1556
            V E + D C +   C+  I     +CV     +   +C C  G  G  C   +  C   P
Sbjct: 856  VVECLSDPCLNNGTCVEKIGVVGYQCVCPDGFAGDFSCACPVGYTGKLCEIDIDDCASMP 915

Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYH 1616
            CG      D     YSCAC P YT      + +  +  P     G+ C   A    +G+ 
Sbjct: 916  CGNLSTCIDHV-NNYSCACVPWYTGRNCENLVTNCDTAP--CQNGATCKIGA----KGFI 968

Query: 1617 PHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
              C        C  N        EC    C+  GS        T  C C PG  G  C+
Sbjct: 969  CDCKAGYTGLACTIN------IDECASSPCFNGGSCRDDVNGYT--CTCAPGYTGSRCE 1019



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 16/39 (41%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  + + CSS+PC +G  C D ++ Y C C  G+ GK C
Sbjct: 1801 CEIRVNNCSSSPCLHGGTCIDGFEDYNCTCPGGYYGKQC 1839



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 16/42 (38%), Positives = 23/42 (54%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            C      C SAPC NGA C D  + Y+C C +G    +C+++
Sbjct: 2201 CTTNIDDCLSAPCKNGATCEDKVNGYLCKCPDGFHSTNCSEN 2242



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 73/307 (23%), Positives = 111/307 (36%), Gaps = 54/307 (17%)

Query: 1059 LTKASC--EVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL-RARSFPVSSF 1115
            L K  C  E +     C +G  CVA   G      C   A +    CE   A +F  ++ 
Sbjct: 1455 LPKPGCRKETNCHAESCANGGTCVATWTGF----QCRCLAEFNGTRCENGTATTFLANTS 1510

Query: 1116 LTFPGLKR---RHRIHLKLKFATQTTSGLLLYNG--RYNERHDFLALELVSSEAGRGGGP 1170
                GL     R      L+  T    GLLLY G        ++L ++LVS +       
Sbjct: 1511 SIQLGLNTTEWRFGQSGSLRVRTSRAIGLLLYAGWKPSGPNTEYLMVDLVSGK------- 1563

Query: 1171 GLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLK 1230
             +R +  LG G   +     V DG WH   I +  +   +IL   D  + ++   +    
Sbjct: 1564 -VRLTADLGSGPGSVINPMTVNDGDWH--HITWSRQYKRLILSVDDVTMEMSTQGE---- 1616

Query: 1231 YACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK--DFVGCISDF 1288
                   + VL       +E  +        + IGG P + SS    +    F GC+ D 
Sbjct: 1617 -------QSVLDVA---DSEIIY--------VHIGGFPYLKSSATGLSTITSFQGCLKDL 1658

Query: 1289 YIDHKFIDLNSYVADNGTLA-------GCPEKRSRCSSAPCYNGAECSDLWDTYICDCKE 1341
               ++++   +  +  G  +       GC      CSS PC   + C +    Y C C  
Sbjct: 1659 TFHYRYVHFLTPFSQQGLASILRNVTTGC-HSIGPCSSNPCQGYSTCENAGGAYNCTCLS 1717

Query: 1342 GHTGKDC 1348
            G TG  C
Sbjct: 1718 GWTGDKC 1724



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 18/196 (9%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  + C   + C        CTC  G     C   +  C+  PC  +    ++    Y+
Sbjct: 2093 DCAANPCLHGATCTDLVGGFVCTCALGYTDHNCSTIIDNCDPNPCNHSGICTNKI-GNYT 2151

Query: 1573 CACEPGYT-LTTSGCIE-SGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC--- 1626
            C C+ GYT    +  I+    + C  G    S+     C    GY   +C      C   
Sbjct: 2152 CLCKGGYTGWNCNTLIDFCYSDPCAYGATCVSSLADYTCACVPGYTGRNCTTNIDDCLSA 2211

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAEVT 1685
             CK N    E       C+C   G  +++C     +C   P + G  C D  A+ YA V 
Sbjct: 2212 PCK-NGATCEDKVNGYLCKC-PDGFHSTNCSENINECDPNPCLNGATCLDKIAD-YACVC 2268

Query: 1686 PN--SG--CEVVYDGC 1697
            P+  SG  C V  + C
Sbjct: 2269 PSGYSGINCSVNVNDC 2284



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 47/195 (24%), Positives = 65/195 (33%), Gaps = 16/195 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  + C   + C+   +  +CTC  G     C   +  C   PC   A CV D   K Y
Sbjct: 2487 DCATNPCRNGATCIDGINKYSCTCPIGFTDQICSTNIDDCATSPCRNGATCV-DGINK-Y 2544

Query: 1572 SCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKCHC 1628
            SC C  G+T  T  +   +     C  G          +C    G+    C+     C  
Sbjct: 2545 SCTCPIGFTDQTCSTNIDDCATNPCRNGATCVDGINKYSCTCPIGFTDQTCSTNIDDCAT 2604

Query: 1629 KE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY-AEVT 1685
                N            C C  AG    +C+    +C  RP     +C    N+Y     
Sbjct: 2605 NPCGNGATCVDEINKYSCLC-PAGFSGGNCQTNIDECASRPCANVGSCIDRINSYECTCV 2663

Query: 1686 P---NSGCEVVYDGC 1697
            P      C+V  D C
Sbjct: 2664 PGYTGRNCQVDIDEC 2678



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 16/40 (40%), Positives = 21/40 (52%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C E  + C   PC NGA C D    Y C C  G++G +C+
Sbjct: 2239 CSENINECDPNPCLNGATCLDKIADYACVCPSGYSGINCS 2278



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 16/31 (51%), Positives = 19/31 (61%)

Query: 1319 SAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            + PC NGA C DL D Y C C  G TG +C+
Sbjct: 2376 AGPCENGATCIDLVDGYRCSCSVGFTGTNCS 2406



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC N   C D  ++Y C C  G+TG++C
Sbjct: 2633 CQTNIDECASRPCANVGSCIDRINSYECTCVPGYTGRNC 2671



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 10/65 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  +TC CP GFTG NC   L    C  +     CR+G+ CV     GI    C+  A +
Sbjct: 2427 INRYTCVCPTGFTGFNCS--LNIDDCSTNP----CRNGATCV----DGINKYSCTCPAGF 2476

Query: 1099 TTAVC 1103
            T   C
Sbjct: 2477 TDQTC 2481



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 14/40 (35%), Positives = 23/40 (57%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C++ PC +GA C+DL   ++C C  G+T  +C+
Sbjct: 2087 CEINTDDCAANPCLHGATCTDLVGGFVCTCALGYTDHNCS 2126



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 16/40 (40%), Positives = 20/40 (50%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C    + C + PC NG  C DL   Y C C  G TG +C+
Sbjct: 2277 CSVNVNDCRTNPCENGGTCIDLIGGYACTCAPGFTGVNCS 2316



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 18/44 (40%), Positives = 21/44 (47%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            T   C      C S PC NGA C D  + Y C C  G TG +C+
Sbjct: 2401 TGTNCSTNIDDCYSDPCKNGASCVDGINRYTCVCPTGFTGFNCS 2444



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 16/41 (39%), Positives = 21/41 (51%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A C  + + C+S+PC N A C D+     C C  G TG  C
Sbjct: 1972 ARCMNRTNVCASSPCQNNATCRDVMGHVKCTCPTGFTGALC 2012



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%)

Query: 1306 TLAGCPEKRSRCSSA--PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T A C    + C S   PC+NG  CS+L  +Y C+C  G  G+ C
Sbjct: 2819 TGARCNIDVNECQSLEQPCFNGGTCSNLDGSYSCECPRGFAGRLC 2863



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 36/166 (21%), Positives = 64/166 (38%), Gaps = 16/166 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C++  D C+ + C   + C    ++ TC C  G  G  C   ++ C   PC   +C  + 
Sbjct: 2747 CETDLDECLSNPCGNGATCRHLVNNYTCICAVGFTGRNCLDDINECGSDPCVHGKC--NN 2804

Query: 1567 TPKGYSCACE-PGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-C 1619
            T   ++C C   G+T     +  + C +S ++ C  G    +  G  +C+  RG+    C
Sbjct: 2805 TIGSFACDCSGTGFTGARCNIDVNEC-QSLEQPCFNGGTCSNLDGSYSCECPRGFAGRLC 2863

Query: 1620 NKENGKCHCKE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663
              +  +C      +  K     +   C C   G     C     +C
Sbjct: 2864 ELDVDECASSPCLHGGKCINLKDQFICHCVGTGFTGFRCGLDVDEC 2909



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 15/43 (34%), Positives = 20/43 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C    + C S PC N   C D    Y C C  G+ G++C  +T
Sbjct: 2049 CQVDINECQSFPCLNSGTCRDEVGNYSCRCPYGYEGRNCEINT 2091



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            CS+ PC NGA C D  + Y C C  G T + C+
Sbjct: 2450 CSTNPCRNGATCVDGINKYSCTCPAGFTDQTCS 2482



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 15/40 (37%), Positives = 21/40 (52%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C+++PC NGA C D  + Y C C  G T + C+
Sbjct: 2519 CSTNIDDCATSPCRNGATCVDGINKYSCTCPIGFTDQTCS 2558



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 15/40 (37%), Positives = 19/40 (47%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C S PC NG  C D    Y C C  G+T ++C+
Sbjct: 2671 CQVDIDECESKPCVNGGTCIDRVAGYSCACAVGYTDQNCS 2710



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 9/67 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  FTC+C +GF G  C   + K  C  +     C++G++C   ++GG     C  +  +
Sbjct: 605  INGFTCKCQDGFIGDRCHAFINK--CLFNP----CKNGAKCQTLQDGG---HRCLCEKGF 655

Query: 1099 TTAVCEL 1105
              ++CE+
Sbjct: 656  KGSLCEV 662



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 1012 ECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGS 1071
            +C T +K    S   N+ +       P T+ TC C  GFTG++CET + +       +G 
Sbjct: 1887 DCNTPMKKCLTSPCKNNGTCYHDAQQPWTNRTCSCIAGFTGMSCETDVDECLSSPCANGG 1946

Query: 1072 ICRSGSQCVARREGGILC 1089
             C S S   A    G +C
Sbjct: 1947 TC-SDSTSSASHFVGFIC 1963



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 49/191 (25%), Positives = 70/191 (36%), Gaps = 25/191 (13%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTC-TCEAGRVGPQC---VSACELGPC-GAARCVPD 1565
            C++ A C          CV ++    C +C AG  G  C   +  C   PC     C  D
Sbjct: 1850 CKNNATCNRRDSDYTCTCVGNFAGELCDSCTAGYTGADCNTPMKKCLTSPCKNNGTCYHD 1909

Query: 1566 -QTP-KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKEN 1623
             Q P    +C+C  G+T     C E+  +EC          G C+   +   H       
Sbjct: 1910 AQQPWTNRTCSCIAGFT--GMSC-ETDVDECLSSPCANG--GTCSDSTSSASH----FVG 1960

Query: 1624 GKCHCKENHYKPEGTAECLPCQCYAAGS---ENSSCEAATG--QCHCRPGVIGRACDACA 1678
              C C + +   EG A C+      A S    N++C    G  +C C  G  G  C+   
Sbjct: 1961 FICACVQGY---EG-ARCMNRTNVCASSPCQNNATCRDVMGHVKCTCPTGFTGALCETDI 2016

Query: 1679 NAYAEVTPNSG 1689
            N  A    N+G
Sbjct: 2017 NECASNPCNNG 2027



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 15/40 (37%), Positives = 20/40 (50%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C++ PC NGA C D  + Y C C  G T + C+
Sbjct: 2557 CSTNIDDCATNPCRNGATCVDGINKYSCTCPIGFTDQTCS 2596



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C++ PC NGA C D  + Y C C  G +G +C
Sbjct: 2595 CSTNIDDCATNPCGNGATCVDEINKYSCLCPAGFSGGNC 2633



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICR 1074
            + C C  GFTG NCET L +      G+G+ CR
Sbjct: 2734 YACSCIPGFTGKNCETDLDECLSNPCGNGATCR 2766



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDC-KEGHTGKDC 1348
            C      C+S+PC +G +C +L D +IC C   G TG  C
Sbjct: 2863 CELDVDECASSPCLHGGKCINLKDQFICHCVGTGFTGFRC 2902



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 45/187 (24%), Positives = 63/187 (33%), Gaps = 24/187 (12%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPK-GYSCA 1574
            DC    C   + C    +S TC+C AG  G  C  +  +  C +  C    T K G +  
Sbjct: 2321 DCASRPCKNGATCNDGVNSYTCSCAAGFSGKNC--SHNIDDCFSMPCKHGATCKDGVAGP 2378

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634
            CE G   T    ++  +  C  G+ G +    C+ ++   Y   C K    C    N Y 
Sbjct: 2379 CENG--ATCIDLVDGYRCSCSVGFTGTN----CSTNIDDCYSDPC-KNGASCVDGINRY- 2430

Query: 1635 PEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP----NSGC 1690
                     C C   G    +C      C   P   G  C    N Y+   P    +  C
Sbjct: 2431 --------TCVC-PTGFTGFNCSLNIDDCSTNPCRNGATCVDGINKYSCTCPAGFTDQTC 2481

Query: 1691 EVVYDGC 1697
                D C
Sbjct: 2482 STNIDDC 2488



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 6/49 (12%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT------YICDCKEGHTGKDCADST 1352
            C      C S+PC NG  CSD   +      +IC C +G+ G  C + T
Sbjct: 1930 CETDVDECLSSPCANGGTCSDSTSSASHFVGFICACVQGYEGARCMNRT 1978



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 15/40 (37%), Positives = 20/40 (50%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C++ PC NGA C D  + Y C C  G T + C+
Sbjct: 2481 CSTNIDDCATNPCRNGATCIDGINKYSCTCPIGFTDQICS 2520



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 31/111 (27%), Positives = 43/111 (38%), Gaps = 19/111 (17%)

Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRP-------IYPVTSFTCQCPEGFTGVN 1054
            CV E  +N   CL    F   +   N D    RP       I  + S+ C C  G+TG N
Sbjct: 2613 CVDE--INKYSCLCPAGFSGGNCQTNIDECASRPCANVGSCIDRINSYECTCVPGYTGRN 2670

Query: 1055 CETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105
            C+  + +  CE       C +G  C+ R  G      C+    YT   C +
Sbjct: 2671 CQVDIDE--CE----SKPCVNGGTCIDRVAG----YSCACAVGYTDQNCSV 2711



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S PC     C D  D+Y C C  G+TG  C
Sbjct: 738  CEININDCASNPCAAYQRCIDRIDSYTCACPLGYTGNAC 776



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 14/32 (43%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C S PC  GA C      Y C C  G+TG++C
Sbjct: 2170 CYSDPCAYGATCVSSLADYTCACVPGYTGRNC 2201



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T A C    + C+S PC NG  C      Y C C +G TG++C
Sbjct: 2008 TGALCETDINECASNPCNNGT-CLQGIGRYDCSCFQGFTGQNC 2049



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C S PC +GA C D    Y C C  G TG +C
Sbjct: 707  CISNPCIHGATCHDGLLGYSCACAVGFTGINC 738



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 14/43 (32%), Positives = 17/43 (39%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C      C+S PC N   C D    + C C  G  G  C + T
Sbjct: 776  CDVNIDECASQPCLNNGTCQDGRGNFSCVCPAGFEGLRCENQT 818



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 13/32 (40%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S PC N + C D  + Y C C   +TG++C
Sbjct: 911  CASMPCGNLSTCIDHVNNYSCACVPWYTGRNC 942



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/41 (34%), Positives = 18/41 (43%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A C      C S PCY    C D  + + C C++G  G  C
Sbjct: 581  ATCDIDIDECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRC 621



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 10/65 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  ++C CP GFT   C T +    C  +     CR+G+ C+     GI    C+    +
Sbjct: 2465 INKYSCTCPAGFTDQTCSTNID--DCATNP----CRNGATCI----DGINKYSCTCPIGF 2514

Query: 1099 TTAVC 1103
            T  +C
Sbjct: 2515 TDQIC 2519



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 5/65 (7%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG---GILCQGCSIDAAY 1098
            + C CP G+ G  CET+ T  +     + +  R  S       G   G LC  C+  A Y
Sbjct: 1826 YNCTCPGGYYGKQCETVDTCFAHACKNNATCNRRDSDYTCTCVGNFAGELCDSCT--AGY 1883

Query: 1099 TTAVC 1103
            T A C
Sbjct: 1884 TGADC 1888



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  + C C  GFTG NC T +    C  D     C++G+ CV     GI    C     +
Sbjct: 2389 VDGYRCSCSVGFTGTNCSTNID--DCYSDP----CKNGASCV----DGINRYTCVCPTGF 2438

Query: 1099 TTAVCEL 1105
            T   C L
Sbjct: 2439 TGFNCSL 2445



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDCADST-GPP 1355
            C + A C++L   Y C C EG+ G+ C + T  PP
Sbjct: 2916 CMHNATCTNLEGGYRCTCVEGYFGEHCENGTLAPP 2950



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 33/128 (25%), Positives = 46/128 (35%), Gaps = 16/128 (12%)

Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061
            C+ +PCLN   C+  +      G V    V   P      F+C CP G+TG  CE  +  
Sbjct: 859  CLSDPCLNNGTCVEKI------GVVGYQCVC--PDGFAGDFSCACPVGYTGKLCEIDIDD 910

Query: 1062 ASCEVDGDGSIC-----RSGSQCV---ARREGGILCQGCSIDAAYTTAVCELRARSFPVS 1113
             +    G+ S C          CV     R    L   C        A C++ A+ F   
Sbjct: 911  CASMPCGNLSTCIDHVNNYSCACVPWYTGRNCENLVTNCDTAPCQNGATCKIGAKGFICD 970

Query: 1114 SFLTFPGL 1121
                + GL
Sbjct: 971  CKAGYTGL 978



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C   PC +   C++    Y C CK G+TG +C
Sbjct: 2125 CSTIIDNCDPNPCNHSGICTNKIGNYTCLCKGGYTGWNC 2163



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 12/38 (31%), Positives = 18/38 (47%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            +  + C C  GFTGVNC   +   +     +G+ C  G
Sbjct: 2299 IGGYACTCAPGFTGVNCSVNIDDCASRPCKNGATCNDG 2336



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/47 (31%), Positives = 18/47 (38%), Gaps = 4/47 (8%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAEC----SDLWDTYICDCKEGHTGKDC 1348
            T A C     +C ++PC N   C       W    C C  G TG  C
Sbjct: 1884 TGADCNTPMKKCLTSPCKNNGTCYHDAQQPWTNRTCSCIAGFTGMSC 1930



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/52 (28%), Positives = 23/52 (44%)

Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSID 1095
            C CP GFTG  CET + + +     +G+  +   +       G   Q C +D
Sbjct: 2001 CTCPTGFTGALCETDINECASNPCNNGTCLQGIGRYDCSCFQGFTGQNCQVD 2052



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 10/65 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  ++C CP GFT   C T +    C  +     CR+G+ CV     GI    C+    +
Sbjct: 2541 INKYSCTCPIGFTDQTCSTNID--DCATNP----CRNGATCV----DGINKYSCTCPIGF 2590

Query: 1099 TTAVC 1103
            T   C
Sbjct: 2591 TDQTC 2595



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 10/65 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  ++C CP GFT   C T +       D   S CR+G+ CV     GI    C+    +
Sbjct: 2503 INKYSCTCPIGFTDQICSTNID------DCATSPCRNGATCV----DGINKYSCTCPIGF 2552

Query: 1099 TTAVC 1103
            T   C
Sbjct: 2553 TDQTC 2557



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 1315 SRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348
            ++C   PC NGA+C  L D  + C C++G  G  C
Sbjct: 626  NKCLFNPCKNGAKCQTLQDGGHRCLCEKGFKGSLC 660



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 13/43 (30%), Positives = 23/43 (53%)

Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            R I  + S+TC CP G+TG  C+  + + + +   +   C+ G
Sbjct: 755  RCIDRIDSYTCACPLGYTGNACDVNIDECASQPCLNNGTCQDG 797



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 11/35 (31%), Positives = 18/35 (51%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073
            +  ++C CP GFT   C T +   +    G+G+ C
Sbjct: 2579 INKYSCTCPIGFTDQTCSTNIDDCATNPCGNGATC 2613



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS-----GSQCVARREGGILCQGCSIDA 1096
            F C CP GF G  CE  + +   +   +   C       G QCV   +G      C+   
Sbjct: 839  FECVCPNGFLGRQCEANVVECLSDPCLNNGTCVEKIGVVGYQCVC-PDGFAGDFSCACPV 897

Query: 1097 AYTTAVCEL 1105
             YT  +CE+
Sbjct: 898  GYTGKLCEI 906



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 23/97 (23%), Positives = 33/97 (34%), Gaps = 8/97 (8%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC---RSGSQCV-ARREGGILC----Q 1090
            +  + C CP G++G+NC   +         +G  C     G  C  A    G+ C     
Sbjct: 2261 IADYACVCPSGYSGINCSVNVNDCRTNPCENGGTCIDLIGGYACTCAPGFTGVNCSVNID 2320

Query: 1091 GCSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRI 1127
             C+       A C     S+  S    F G    H I
Sbjct: 2321 DCASRPCKNGATCNDGVNSYTCSCAAGFSGKNCSHNI 2357


>SB_4874| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 473

 Score = 72.9 bits (171), Expect = 3e-12
 Identities = 62/201 (30%), Positives = 89/201 (44%), Gaps = 18/201 (8%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
           F   Q+  E+ E+   G  V T+ A    +  ++ YE+   N       T +   G ITV
Sbjct: 220 FFSKQHSAEVRENSRRGAYVTTVRAVSFSKPRKIRYELIAENLLPPTHFTIEETTGTITV 279

Query: 426 AQPLDFKQERRYVLTVSA---TDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFE 480
           A  LD +++  Y+L V A     +G  S  A   V + I+D N+  P+F    Y   V  
Sbjct: 280 AGDLDREEKDSYLLEVGAGLQYPNGTLSRVARTYVMVKISDENDNYPIFGLPSYHVRVPC 339

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +   G TV  V+A D D+G NA+I Y L  +         +  F I P TG I   + L 
Sbjct: 340 NTTAGRTVYRVTAMDRDLGDNARIRYRLQPK---------NMYFTILPHTGKIRVTQDLH 390

Query: 541 R----ETMSGYLLTVTARDGG 557
           R        G+ L+V ARD G
Sbjct: 391 RFCNMRPARGFTLSVLARDYG 411



 Score = 72.5 bits (170), Expect = 4e-12
 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 13/185 (7%)

Query: 504 ITYSLSSEISNEAVAHH---DQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR---DGG 557
           +++S   +I  E +A +      F I   TG IT    LDRE    YLL V A      G
Sbjct: 245 VSFSKPRKIRYELIAENLLPPTHFTIEETTGTITVAGDLDREEKDSYLLEVGAGLQYPNG 304

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
             S    T V + + D NDN P+F    Y   +  +   G +V +V A D D+G N RI 
Sbjct: 305 TLSRVARTYVMVKISDENDNYPIFGLPSYHVRVPCNTTAGRTVYRVTAMDRDLGDNARIR 364

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDR----ESVATHDLKAVAIDGGTPPQSSTVIV 673
           Y L PK+     F I P +G IR  + L R           L  +A D G  P+++   +
Sbjct: 365 YRLQPKNM---YFTILPHTGKIRVTQDLHRFCNMRPARGFTLSVLARDYGKLPETAHAWM 421

Query: 674 HIKIE 678
           +I+++
Sbjct: 422 YIEVK 426



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 53/173 (30%), Positives = 79/173 (45%), Gaps = 15/173 (8%)

Query: 187 IRYAIIGGNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA---QDGGSPSRSNTT 241
           IRY +I  N      F+I+  +G +++   LD E+  SY L + A      G+ SR   T
Sbjct: 253 IRYELIAENLLPPTHFTIEETTGTITVAGDLDREEKDSYLLEVGAGLQYPNGTLSRVART 312

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            +++ I D NDN P F    +   V  N   G ++ RV A D D G NA + Y +  K  
Sbjct: 313 YVMVKISDENDNYPIFGLPSYHVRVPCNTTAGRTVYRVTAMDRDLGDNARIRYRLQPK-- 370

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATA 350
               ++  TI P +G +  +  L R    +    + L V A D G  P +A A
Sbjct: 371 ----NMYFTILPHTGKIRVTQDLHRFCNMRPARGFTLSVLARDYGKLPETAHA 419



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 62/231 (26%), Positives = 102/231 (44%), Gaps = 29/231 (12%)

Query: 23  FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXX 82
           F  +Q+ A VRE +  G  V T++A      K  ++ Y  EL+  + L P          
Sbjct: 220 FFSKQHSAEVRENSRRGAYVTTVRAVS--FSKPRKIRY--ELIAENLLPPTH-------- 267

Query: 83  XXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ-ASPVSDRLSSTATIHVNII 141
                  F I+  +G +     LDRE+   Y + V A  Q  +    R++ T  + V I 
Sbjct: 268 -------FTIEETTGTITVAGDLDREEKDSYLLEVGAGLQYPNGTLSRVARTYVM-VKIS 319

Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201
           D+NDNYP F   +Y V V    + T    + ++ A D D+G N+ IRY +   N  M F+
Sbjct: 320 DENDNYPIFGLPSYHVRV--PCNTTAGRTVYRVTAMDRDLGDNARIRYRLQPKN--MYFT 375

Query: 202 IDSLSGDVSLVKTL----DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           I   +G + + + L    +    R + L + A+D G    +    + I ++
Sbjct: 376 ILPHTGKIRVTQDLHRFCNMRPARGFTLSVLARDYGKLPETAHAWMYIEVK 426



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 41/151 (27%), Positives = 69/151 (45%), Gaps = 6/151 (3%)

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVI 639
           F  + ++A + E++  G  V+ V A         +I YEL  ++    + F I+  +G I
Sbjct: 220 FFSKQHSAEVRENSRRGAYVTTVRAVS--FSKPRKIRYELIAENLLPPTHFTIEETTGTI 277

Query: 640 RTNKALDRESVATHDLKAVA---IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
                LDRE   ++ L+  A      GT  + +   V +KI D ND+ P+F        +
Sbjct: 278 TVAGDLDREEKDSYLLEVGAGLQYPNGTLSRVARTYVMVKISDENDNYPIFGLPSYHVRV 337

Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
             N+  G T+  + A D D G NA + Y ++
Sbjct: 338 PCNTTAGRTVYRVTAMDRDLGDNARIRYRLQ 368



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 17/53 (32%), Positives = 30/53 (56%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63
           + + D ND+ P+F +  Y   V    ++G TV  + A D+D+G NA + Y ++
Sbjct: 316 VKISDENDNYPIFGLPSYHVRVPCNTTAGRTVYRVTAMDRDLGDNARIRYRLQ 368



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 9/78 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAG------RVGPQCVSACELGPCGAARCVPD--QT 1567
            +C   +C     C  +  S  C C  G      R   +CV   E G  GAARC      T
Sbjct: 136  ECERPVCSFPRLCRNTLGSYACDCPEGYENRGRRDSDKCVDIDECGS-GAARCDHKCVNT 194

Query: 1568 PKGYSCACEPGYTLTTSG 1585
               Y C C  GYTL   G
Sbjct: 195  EGSYHCRCRKGYTLAPDG 212


>SB_23044| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2162

 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 77/275 (28%), Positives = 111/275 (40%), Gaps = 32/275 (11%)

Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDL-WDTYICDCKEGHTGKDCADSTG 1353
            D +     N T   C   ++RC    PC NG  C D+ ++ + CDC  G  G  C +ST 
Sbjct: 908  DFSCNCTANYTGRQCEYLKTRCRPINPCLNGGRCKDIGFENFTCDCSAGFGGPLCENSTT 967

Query: 1354 PPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS-------IQLKSGLLHYSY 1406
                  G   L+F+      Q  ++ AL  RT   D  ++        +QLK G +  S 
Sbjct: 968  VS--LNGSSYLTFDGS----QSEFMVALEFRTTLADGVLVHDSESKFLMQLKEGAIEIS- 1020

Query: 1407 NGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466
            NG       A LSDG W  I ++   T   + +     +V +  + N+       K+ IG
Sbjct: 1021 NGVNSAAIGAALSDGNWSGI-VRLNVTQSHLQLSINTSSVSITRI-NRTNP----KLFIG 1074

Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRD--GCQSRADCMLSICPP 1524
            G    +G L S      GCI+DV++     L   P+  E VR   GC     C    C  
Sbjct: 1075 GY---SGNLQSSRNLI-GCIRDVKVNGVVKL---PSEIELVRVSMGCPREEVCSPDPCTN 1127

Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGA 1559
               C+  W +  C C     GP C ++   G  GA
Sbjct: 1128 -GTCIDEWLTYRCACYRRWTGPNCSTSFVAGTFGA 1161



 Score = 55.6 bits (128), Expect = 5e-07
 Identities = 44/170 (25%), Positives = 68/170 (40%), Gaps = 17/170 (10%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  ++C   + CV   ++ TC C +G  G  C   ++ CE  PC       ++  K ++
Sbjct: 620  DCASALCVANATCVDLLNNYTCKCPSGYHGDLCQFDINECESNPCRNNGTCKNEEGK-FT 678

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGYH-PHCNKENGKC- 1626
            C C  G+  T   C E   ++CP        C        C    G+   HC K+  +C 
Sbjct: 679  CTCLSGFNGTF--C-EVNIDDCPAIGCNNGTCIDGINNYTCQCFIGFEGRHCEKDIDECS 735

Query: 1627 --HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
              +CK N      T     CQC    +  ++CE    +C   P + G  C
Sbjct: 736  LGYCK-NGATCTNTPGNYSCQC-TEFTNGTNCELDINECASSPCLNGALC 783



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 18/39 (46%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C   R +C S PC NG  C    D Y C C+  HTGK+C
Sbjct: 2007 CDILRDKCDSNPCQNGGRCKSTRDGYTCQCEPSHTGKNC 2045



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 10/98 (10%)

Query: 1256 LDLTGP-LQIGGLP-NIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEK 1313
            ++ T P L IGG   N+ SS     ++ +GCI D  ++   + L S +       GCP +
Sbjct: 1064 INRTNPKLFIGGYSGNLQSS-----RNLIGCIRDVKVNG-VVKLPSEIELVRVSMGCPRE 1117

Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
               CS  PC NG  C D W TY C C    TG +C+ S
Sbjct: 1118 EV-CSPDPCTNGT-CIDEWLTYRCACYRRWTGPNCSTS 1153



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 67/303 (22%), Positives = 120/303 (39%), Gaps = 38/303 (12%)

Query: 1379 NALSIRTRQRDAFVMSIQLKSGLLH--YSYNGETMYLPMATL-SDGAWHRIEIKWLGTDI 1435
            NA+ +++RQ  +  + ++L+SG L+  Y++ G T  +    + ++G W+ +      T +
Sbjct: 1502 NAVLLQSRQDASNFLEVRLESGYLNVTYAFGGNTGTVKTGVVVNNGEWYHVTFNATST-L 1560

Query: 1436 SVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQ 1495
             ++V+             + +G + G  L   L +T         FF+GC+ +VR+G A 
Sbjct: 1561 LLSVNQS---------QTEKEGSFTGTELQNLLASTPISFGLAQPFFKGCLDNVRVGGA- 1610

Query: 1496 SLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG 1555
             LL  P +              + S+ P +   VTS +     C +         AC + 
Sbjct: 1611 -LL--PFIPYY---NATYNVSHVTSLKPRFD--VTSINGINTGCRSD-------DACAVR 1655

Query: 1556 PCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECP-GGWWGGSAC-GPCACDVTR 1613
            PC   +C  D     + CAC  GY      C  +    C     + GS C    A ++T+
Sbjct: 1656 PCMRGQCSDDW--NAFKCACPEGYAGMV--CNLTANMTCAHAPCFNGSTCENRTAANLTQ 1711

Query: 1614 GYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGR 1672
                +   +   CHC       +  A    C+    G+  +  ++     C C  G  GR
Sbjct: 1712 --ISNVGIDQFVCHCAPGFEGRQCNATTDECKSNPCGNYGTCTDSHLNYSCACVSGFTGR 1769

Query: 1673 ACD 1675
             C+
Sbjct: 1770 NCE 1772



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 20/153 (13%)

Query: 1533 DSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIES 1589
            D   C C  G  G QC      C+  PCG      D +   YSCAC  G+  T   C E 
Sbjct: 1718 DQFVCHCAPGFEGRQCNATTDECKSNPCGNYGTCTD-SHLNYSCACVSGF--TGRNC-EI 1773

Query: 1590 GKEECPG-GWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
              ++C G      S C     D+   Y+  C       +C+ +        ECL   C +
Sbjct: 1774 DIDDCVGNNCTNNSTC----VDLIDDYNCTCQVGYNGSYCELD------IDECLANPCSS 1823

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
             GS N++    + +C C+ G  G  C   A+ +
Sbjct: 1824 YGSCNNT--IGSYECVCKQGYYGNHCQYNASQW 1854



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 44/162 (27%), Positives = 63/162 (38%), Gaps = 16/162 (9%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCE-AGRVGPQC---VSACEL--GPC-GAARCV 1563
            C+   D   S+   + KCV   ++ TC C  +G  GP+C   ++ C++  GPC     C 
Sbjct: 313  CEQNIDDCASLPCKHGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNGGTC- 371

Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGG--SACGPCACDVTRGYHPHCNK 1621
             D     Y C+C+ GY      C E+  E  P     G  S C   A     G   H +K
Sbjct: 372  -DNYLGTYGCSCKAGY--RGKNCQENIDECDPNPCLNGATSRCTRPAIVCAIGRPRHMSK 428

Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663
             N  C+   +    +G      C C+  G     CE     C
Sbjct: 429  -NFLCYLLPSGTCVDG-INGFNCSCF-IGFTGERCETNIDDC 467



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C S PC + A C+DL + + C+C   +TG+ C
Sbjct: 884  CSEDINECLSTPCQHNATCNDLVNDFSCNCTANYTGRQC 922



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGA-ARCVPDQTPKGY 1571
            DC+ + C   S CV   D   CTC+ G  G  C   +  C   PC +   C  + T   Y
Sbjct: 1777 DCVGNNCTNNSTCVDLIDDYNCTCQVGYNGSYCELDIDECLANPCSSYGSC--NNTIGSY 1834

Query: 1572 SCACEPGY 1579
             C C+ GY
Sbjct: 1835 ECVCKQGY 1842



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 44/167 (26%), Positives = 59/167 (35%), Gaps = 24/167 (14%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC+ + C     CV   ++ TC C+ G  G  C   +  C   PC     C   +   GY
Sbjct: 466  DCVSNTCNANQDCVDQVNNYTCVCKPGFTGSDCSVDILECLSNPCRHGGTC--HEGVNGY 523

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSAC---GPCACDVTRGYHPHCNKENGKCHC 1628
            +C C P +  T   C      +C       S C   G C  DV   ++  C K      C
Sbjct: 524  NCTCLPRFNGT--HCELDTVNDC-----NSSPCLNNGTCVDDV-GFFNCTCPKGFDGVRC 575

Query: 1629 KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
            +        +  C P  C    S N   E     C C  G  G+ CD
Sbjct: 576  ENK------SDSCHPNPCKHGASCNIVNE-TDFTCACPTGYTGKTCD 615



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 17/47 (36%), Positives = 25/47 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPW 1356
            C      C+SAPC++ + C D  + Y C C    TG+DC+ + G  W
Sbjct: 209  CEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLW 255



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            NG   GC      C+  PC  G +CSD W+ + C C EG+ G  C
Sbjct: 1640 NGINTGC-RSDDACAVRPCMRG-QCSDDWNAFKCACPEGYAGMVC 1682



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 15/124 (12%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQ 1566
            C+   D   +I      C+   ++ TC C  G  G  C   +  C LG C   A C    
Sbjct: 690  CEVNIDDCPAIGCNNGTCIDGINNYTCQCFIGFEGRHCEKDIDECSLGYCKNGATCT--N 747

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNKENGK 1625
            TP  YSC C   +T  T+ C E    EC       G+ C    CD T      C+ +  +
Sbjct: 748  TPGNYSCQCTE-FTNGTN-C-ELDINECASSPCLNGALCQNNDCDKTA-----CSDKGYE 799

Query: 1626 CHCK 1629
            C CK
Sbjct: 800  CFCK 803



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 14/31 (45%), Positives = 19/31 (61%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            PC NG  C +   TY C CK G+ GK+C ++
Sbjct: 364  PCLNGGTCDNYLGTYGCSCKAGYRGKNCQEN 394



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C+ +PC  G  C+D W+ Y C C   + G DC+
Sbjct: 1354 CARSPCGMGGTCNDRWNKYECSCSPRYGGPDCS 1386



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348
            C  K   C   PC +GA C+ + +T + C C  G+TGK C
Sbjct: 575  CENKSDSCHPNPCKHGASCNIVNETDFTCACPTGYTGKTC 614



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    S C+  PC NG  C  L D YIC+C   + G++C
Sbjct: 1970 CSGLLSYCTPNPCING-NCIPLMDNYICECDSKYLGRNC 2007



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 11/108 (10%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  F+C C   +TG  CE + T+  C        C +G +C   ++ G     C   A +
Sbjct: 906  VNDFSCNCTANYTGRQCEYLKTR--CRPINP---CLNGGRC---KDIGFENFTCDCSAGF 957

Query: 1099 TTAVCELRAR-SFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN 1145
               +CE     S   SS+LTF G +    +   L+F T    G+L+++
Sbjct: 958  GGPLCENSTTVSLNGSSYLTFDGSQSEFMV--ALEFRTTLADGVLVHD 1003



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 15/39 (38%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C S PC N   C+D    Y C C  G TG++C
Sbjct: 1733 CNATTDECKSNPCGNYGTCTDSHLNYSCACVSGFTGRNC 1771



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C      C S  C    +C D  + Y C CK G TG DC+    +    P R GG
Sbjct: 460  CETNIDDCVSNTCNANQDCVDQVNNYTCVCKPGFTGSDCSVDILECLSNPCRHGG 514



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 42/182 (23%), Positives = 67/182 (36%), Gaps = 21/182 (11%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA-CE-LGPCGAARCVPDQTP 1568
            C + A C  +    Y  C   W+   C+ +      +C S  C+  G C  +  V +  P
Sbjct: 1861 CMNNATCSGNATGFYCTCAEGWEGKLCSVDI----KECESTPCQNNGTCTDSHSVSEFFP 1916

Query: 1569 KGYSCACEPGYTLTTSGCIESGKEECP---GGWWGGSACGPCACDVTRGYHPHCNKENGK 1625
             GY CAC   YT  +   + +  +E P    G     +     C+ T GY  + N     
Sbjct: 1917 -GYRCACTVDYTGPSCEKLVTPCDEKPCLNNGSCIRLSYNKYECNCTEGY-GNMNCSGLL 1974

Query: 1626 CHCKENHYKPEGTAECLP------CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
             +C  N   P     C+P      C+C  +     +C+    +C   P   G  C +  +
Sbjct: 1975 SYCTPN---PCINGNCIPLMDNYICEC-DSKYLGRNCDILRDKCDSNPCQNGGRCKSTRD 2030

Query: 1680 AY 1681
             Y
Sbjct: 2031 GY 2032



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 14/105 (13%)

Query: 1002 CVHEPCLNFEEC-LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILT 1060
            C   P  N   C L  +   N+S  +N+ +     +  V  F C CP+GF GV CE    
Sbjct: 525  CTCLPRFNGTHCELDTVNDCNSSPCLNNGTC----VDDVGFFNCTCPKGFDGVRCEN--K 578

Query: 1061 KASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105
              SC  +     C+ G+ C    E       C+    YT   C++
Sbjct: 579  SDSCHPNP----CKHGASCNIVNETDFT---CACPTGYTGKTCDI 616



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 14/32 (43%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+SA C   A C DL + Y C C  G+ G  C
Sbjct: 621  CASALCVANATCVDLLNNYTCKCPSGYHGDLC 652



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 14/39 (35%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    CS   C NGA C++    Y C C E   G +C
Sbjct: 727  CEKDIDECSLGYCKNGATCTNTPGNYSCQCTEFTNGTNC 765



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 20/70 (28%), Positives = 26/70 (37%), Gaps = 3/70 (4%)

Query: 1514 RADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKG 1570
            R  C  + C    +C ++ D  TC CE    G  C   S C   PC     C        
Sbjct: 2011 RDKCDSNPCQNGGRCKSTRDGYTCQCEPSHTGKNCQLPSPCFRNPCENNGVCKIHPVHFN 2070

Query: 1571 YSCACEPGYT 1580
            Y+C C   +T
Sbjct: 2071 YTCNCTDTFT 2080



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 13/32 (40%), Positives = 16/32 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    C N + C DL D Y C C+ G+ G  C
Sbjct: 1778 CVGNNCTNNSTCVDLIDDYNCTCQVGYNGSYC 1809



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDL-WDTYICDCKEGHTGKDCA 1349
            C +  + C   PC N   C  L ++ Y C+C EG+   +C+
Sbjct: 1931 CEKLVTPCDEKPCLNNGSCIRLSYNKYECNCTEGYGNMNCS 1971



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 11/80 (13%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVP- 1564
            C+   D C L  C   + C  +  + +C C     G  C   ++ C   PC   A C   
Sbjct: 727  CEKDIDECSLGYCKNGATCTNTPGNYSCQCTEFTNGTNCELDINECASSPCLNGALCQNN 786

Query: 1565 --DQTP---KGYSCACEPGY 1579
              D+T    KGY C C+ G+
Sbjct: 787  DCDKTACSDKGYECFCKSGF 806



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 17/70 (24%), Positives = 34/70 (48%), Gaps = 10/70 (14%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            ++ C+C   + G NC+ +  K       D + C++G +C + R+G      C  + ++T 
Sbjct: 1993 NYICECDSKYLGRNCDILRDKC------DSNPCQNGGRCKSTRDG----YTCQCEPSHTG 2042

Query: 1101 AVCELRARSF 1110
              C+L +  F
Sbjct: 2043 KNCQLPSPCF 2052



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 10/65 (15%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            +++C C  GFTG NCE  +       D  G+ C + S CV   +       C+    Y  
Sbjct: 1757 NYSCACVSGFTGRNCEIDID------DCVGNNCTNNSTCVDLIDD----YNCTCQVGYNG 1806

Query: 1101 AVCEL 1105
            + CEL
Sbjct: 1807 SYCEL 1811



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 14/49 (28%), Positives = 22/49 (44%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRF 1358
            C      C + PC +   C++   +Y C CK+G+ G  C  +     RF
Sbjct: 1809 CELDIDECLANPCSSYGSCNNTIGSYECVCKQGYYGNHCQYNASQWCRF 1857



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 29/108 (26%), Positives = 40/108 (37%), Gaps = 15/108 (13%)

Query: 1465 IGGLDTTAGLLASDVGF---FEGCIQDVRIGT--------AQSLLNRPT--VRENVRDGC 1511
            +GGL+        DV       GCI D R+ +        + S  + P   +  N+  GC
Sbjct: 1289 LGGLENWTAYQQEDVVTKIPLRGCIHDARLNSKLLQFFPVSSSEESFPLLGIASNLGRGC 1348

Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC-VSACEL-GPC 1557
                 C  S C     C   W+   C+C     GP C +  C L  PC
Sbjct: 1349 LGENVCARSPCGMGGTCNDRWNKYECSCSPRYGGPDCSLYGCALVKPC 1396



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 48/204 (23%), Positives = 63/204 (30%), Gaps = 26/204 (12%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC----VSACEL-GPC-GAARCVPDQTPK 1569
            +C+ + C  Y  C  +  S  C C+ G  G  C       C    PC   A C  + T  
Sbjct: 1815 ECLANPCSSYGSCNNTIGSYECVCKQGYYGNHCQYNASQWCRFQQPCMNNATCSGNAT-- 1872

Query: 1570 GYSCACEPGY--TLTTSGCIESGKEECPGGW-----WGGSACGP---CACDVTRGYHPHC 1619
            G+ C C  G+   L +    E     C            S   P   CAC V     P C
Sbjct: 1873 GFYCTCAEGWEGKLCSVDIKECESTPCQNNGTCTDSHSVSEFFPGYRCACTVDY-TGPSC 1931

Query: 1620 NKENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676
             K    C    C  N      +     C C   G  N +C      C   P + G     
Sbjct: 1932 EKLVTPCDEKPCLNNGSCIRLSYNKYECNC-TEGYGNMNCSGLLSYCTPNPCINGNCIPL 1990

Query: 1677 CANAYAEVTP---NSGCEVVYDGC 1697
              N   E         C+++ D C
Sbjct: 1991 MDNYICECDSKYLGRNCDILRDKC 2014



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 12/36 (33%), Positives = 18/36 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C+S+PC N   C D    + C C +G  G  C + +
Sbjct: 544  CNSSPCLNNGTCVDDVGFFNCTCPKGFDGVRCENKS 579



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 13/29 (44%), Positives = 15/29 (51%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            PC N A CS     + C C EG  GK C+
Sbjct: 1860 PCMNNATCSGNATGFYCTCAEGWEGKLCS 1888


>SB_16968| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 1101

 Score = 70.9 bits (166), Expect = 1e-11
 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 12/96 (12%)

Query: 1607 CACDVTRGY-HPHCNKENGKCHCKE-------NHYKPE----GTAECLPCQCYAAGSENS 1654
            C CD    Y +  C++  GKC CK        +  KP      ++ C PC C + GS + 
Sbjct: 729  CGCDSVGTYLNSTCDRYGGKCQCKPGVTGRTCDKCKPGFYNFTSSGCAPCDCVSTGSHHL 788

Query: 1655 SCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
             C A +GQC C+PGVI R C  C +++   T  SGC
Sbjct: 789  VCNAVSGQCPCKPGVITRTCSRCNDSFYGYTTGSGC 824



 Score = 70.9 bits (166), Expect = 1e-11
 Identities = 52/203 (25%), Positives = 76/203 (37%), Gaps = 23/203 (11%)

Query: 1510 GCQSRADCMLSICPPYS-KCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQ-- 1566
            GC S    + S C  Y  KC      +  TC+  + G    ++    PC           
Sbjct: 730  GCDSVGTYLNSTCDRYGGKCQCKPGVTGRTCDKCKPGFYNFTSSGCAPCDCVSTGSHHLV 789

Query: 1567 -TPKGYSCACEPGY-TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG 1624
                   C C+PG  T T S C +S       G+  GS C  C C+++      C+   G
Sbjct: 790  CNAVSGQCPCKPGVITRTCSRCNDSFY-----GYTTGSGCVECRCNMSGSADAQCDDVTG 844

Query: 1625 KCHCKENH-----------YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRA 1673
             C CK +            +    +A C  C C+  GS++  C   TG C C+   +G  
Sbjct: 845  NCTCKNSTDGAKCAECRFGFYNFTSAGCQACNCHEGGSQSQQCNLQTGICTCKSNALGEK 904

Query: 1674 CDACANAYAEVTPNS--GCEVVY 1694
            C++C        PN+  GC   Y
Sbjct: 905  CESCRPGTYHSDPNNPDGCTPCY 927



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 7/69 (10%)

Query: 1620 NKENGKCH-CKENHYKPEGTAE-----CLPCQCYAAG-SENSSCEAATGQCHCRPGVIGR 1672
            N E   C  CK+  Y+    +      C  C C+  G + N +C   TGQC CR  V GR
Sbjct: 347  NTEGHFCERCKDKFYRNMSLSLNHPEICPDCNCFPQGITNNGTCNQTTGQCECRANVTGR 406

Query: 1673 ACDACANAY 1681
             CD+CA+ +
Sbjct: 407  QCDSCADTF 415



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 36/146 (24%), Positives = 50/146 (34%), Gaps = 21/146 (14%)

Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSA-----CGPCAC-- 1609
            C    C P       +C    G     +       + C   +WG +      C  C C  
Sbjct: 374  CPDCNCFPQGITNNGTCNQTTGQCECRANVTGRQCDSCADTFWGYTLEPIGYCTECLCVG 433

Query: 1610 DVTRGYHPHCNKENGKCHCKEN-HYK------------PEGT-AECLPCQCYAAGSENSS 1655
            + T     +C++ NG+C CK N H +            P+    +C  C C   GS    
Sbjct: 434  NGTVNASLNCDQYNGQCSCKPNVHTRTCQECKHGYWDFPKTLDTDCKRCDCDYGGSVLQI 493

Query: 1656 CEAATGQCHCRPGVIGRACDACANAY 1681
            C   TG C CR  +IG  C      Y
Sbjct: 494  CNKTTGSCMCRTNIIGTRCTDVTTGY 519



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 19/85 (22%)

Query: 1593 ECPGGWWGGSACGPCACDVTRG--YHPHCNKENGKCHCKEN--------------HYKPE 1636
            EC  G++  ++ G  AC+   G      CN + G C CK N              H  P 
Sbjct: 859  ECRFGFYNFTSAGCQACNCHEGGSQSQQCNLQTGICTCKSNALGEKCESCRPGTYHSDPN 918

Query: 1637 GTAECLPCQCYAAGSENSSCEAATG 1661
                C PC C+     +++C +A+G
Sbjct: 919  NPDGCTPCYCF---GRSNTCTSASG 940


>SB_35857| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2680

 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 20/161 (12%)

Query: 1546 PQCVSACELGPCGAARCVPDQTPKG-YSCACEPGYTLTTSGCIESGKEECPGGWW---GG 1601
            P+   AC   P G      D+TP G   C+   G     +       ++C   ++    G
Sbjct: 762  PEGCQACNCNPKGTLG--GDRTPAGELECSGSNGKCACLTNVQGLRCDQCVSAYYWNPSG 819

Query: 1602 SACGPCACDVTRGYHPHCNKENGKCHCKEN-------HYKPE---GTAECLPCQCYAAGS 1651
              C PC CD +     +CN   G C CK N          P    G   C PC C  AGS
Sbjct: 820  YGCSPCNCDASGSLATNCNS-TGYCQCKPNIGGRRCDRCMPGSYGGPGSCKPCNCNMAGS 878

Query: 1652 ENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNS--GC 1690
             + +C+ + G+C+C+P V G  CD C +    +  N+  GC
Sbjct: 879  LSDTCDDS-GKCNCKPNVQGDKCDTCKDGTQNLQVNNDFGC 918



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 51/166 (30%), Positives = 68/166 (40%), Gaps = 25/166 (15%)

Query: 1517 CMLSICPPY----SKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYS 1572
            C L  C P     S       S  CTC+     P C   C  G    +   P+      +
Sbjct: 712  CSLCSCDPKGIQGSSLTCEVSSGNCTCKKYVREPTC-GQCMKGYFNLSSSNPEGCQ---A 767

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632
            C C P  TL       +G+ EC G      + G CAC +T      C++      C   +
Sbjct: 768  CNCNPKGTLGGDRT-PAGELECSG------SNGKCAC-LTNVQGLRCDQ------CVSAY 813

Query: 1633 Y-KPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC 1677
            Y  P G   C PC C A+GS  ++C + TG C C+P + GR CD C
Sbjct: 814  YWNPSGYG-CSPCNCDASGSLATNCNS-TGYCQCKPNIGGRRCDRC 857



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 16/112 (14%)

Query: 1587 IESGKEECP-GGWWGGSACGPCAC-DVTRGYHPHCNKENGKCHCKENHY--KPEGTAECL 1642
            +E+GK  C       G   G C C   T+G    C+       CK   Y  K   +  C+
Sbjct: 506  VETGKTSCARDDSTPGVIAGQCECKQYTQGRQ--CDA------CKPGFYDLKSSHSTGCV 557

Query: 1643 PCQCYAAGS--ENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPN--SGC 1690
             C C  AG+   N+SC+ + GQC+C+  V GR CD C + +  +  N  SGC
Sbjct: 558  TCGCNTAGTVNRNASCDQSRGQCYCKSNVTGRTCDTCESGFYGLRDNDPSGC 609



 Score = 56.0 bits (129), Expect = 4e-07
 Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 33/162 (20%)

Query: 1537 CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGY-SCACEPGYTLTTSGCIESGKEECP 1595
            C C++   G  C   CE G  G    + D  P G  +C C+P  TL  S C ++G     
Sbjct: 580  CYCKSNVTGRTC-DTCESGFYG----LRDNDPSGCRACECDPFGTLPGSVC-DAGS---- 629

Query: 1596 GGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN-- 1653
                     G C C               +CH  E+ Y    ++ C  C C   G++   
Sbjct: 630  ---------GQCRCKA--------GSTGLRCHLCEDGYHSLDSSGCKTCNCSTIGAKPGL 672

Query: 1654 -SSCEAATGQCHCRPGVIGRACDACANAYAEVTP--NSGCEV 1692
             ++C+   GQC+C+  V G+ CD C   Y  +T     GC +
Sbjct: 673  VNTCDKTNGQCYCKTYVEGKTCDRCKTGYYNLTTVNQDGCSL 714



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 54/226 (23%), Positives = 74/226 (32%), Gaps = 42/226 (18%)

Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG------- 1555
            +R+N   GC++  +C      P S C     S  C C+AG  G +C   CE G       
Sbjct: 601  LRDNDPSGCRA-CECDPFGTLPGSVCDAG--SGQCRCKAGSTGLRC-HLCEDGYHSLDSS 656

Query: 1556 PCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGK--EECPGGWWG-----GSACGPCA 1608
             C    C       G    C+             GK  + C  G++         C  C+
Sbjct: 657  GCKTCNCSTIGAKPGLVNTCDKTNGQCYCKTYVEGKTCDRCKTGYYNLTTVNQDGCSLCS 716

Query: 1609 CDVT--RGYHPHCNKENGKCHCKENHYKP--------------EGTAECLPCQCYAAGSE 1652
            CD    +G    C   +G C CK+   +P                   C  C C   G+ 
Sbjct: 717  CDPKGIQGSSLTCEVSSGNCTCKKYVREPTCGQCMKGYFNLSSSNPEGCQACNCNPKGTL 776

Query: 1653 NSS--------CEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
                       C  + G+C C   V G  CD C +AY       GC
Sbjct: 777  GGDRTPAGELECSGSNGKCACLTNVQGLRCDQCVSAYYWNPSGYGC 822



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 15/87 (17%)

Query: 1626 CH-CKENHYKPEGTA-----ECLPCQCYAAGSENSSCEAA---------TGQCHCRPGVI 1670
            CH C+++ ++  G +      C PCQC   G E      A          GQC C+    
Sbjct: 475  CHVCRDDFFREPGKSLSAVDVCSPCQCTGPGVETGKTSCARDDSTPGVIAGQCECKQYTQ 534

Query: 1671 GRACDACANAYAEVTPNSGCEVVYDGC 1697
            GR CDAC   + ++  +     V  GC
Sbjct: 535  GRQCDACKPGFYDLKSSHSTGCVTCGC 561



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 37/118 (31%), Positives = 52/118 (44%), Gaps = 11/118 (9%)

Query: 1418 LSDGAWHRIEIKWLGT-DISVTVDYGLRTVLMPMLANKIQGQ-YIGKILIGGLDTTAGLL 1475
            L DG WHR+EI  +G      TVD G++ V   +    +    YIG I +   +  A   
Sbjct: 1608 LCDGFWHRVEITGVGNFSFVFTVD-GVKNVETAVDKIAVTSPLYIGGIPLDNNNAVAAAN 1666

Query: 1476 ASDVGF---FEGCIQDVRIGTAQSLLNRP--TVRENVRDGCQSRADCMLSICPPYSKC 1528
             + +     F GCI+DV   T   L  R    +R +  DGC S     L++  P S C
Sbjct: 1667 KAGLDIQDTFGGCIRDVTTDT-NVLFGREVLAMRNSDLDGCVSNK--TLNVTQPSSAC 1721



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 9/106 (8%)

Query: 1110 FPVSSFLTFPGLKRRHRI--HLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRG 1167
            FP + +  FPG   R      ++L F TQ   GL+L+    ++  D LA+ L      R 
Sbjct: 1339 FPGNGYYKFPGSYVREGTTNEIELWFRTQYPDGLILFLSDSSQA-DLLAVVL------RE 1391

Query: 1168 GGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILD 1213
            G P   F    G     ++      D  WH +++   +   T+ +D
Sbjct: 1392 GKPWFIFDCQTGPAAFTVSAAVTFDDNQWHRLQLTRKDSVGTLTVD 1437


>SB_35310| Best HMM Match : Cadherin (HMM E-Value=5.9e-23)
          Length = 1250

 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 165/757 (21%), Positives = 289/757 (38%), Gaps = 72/757 (9%)

Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           SL+  +VA   + ++ATD  +P   R        V I+D ND     S   +TV+ +  +
Sbjct: 269 SLNNGEVA---ITIRATDNGNPPMWREQE---FKVRILDVNDPPGNISLSNHTVNKNAQV 322

Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
                 V   I   D     +S   + +   +  + F ++    ++ + K L+       
Sbjct: 323 GSLVG-VFTAIDGDDPTATPSSNFTWELTNSSNGL-FKLNG--SNLVVAKPLNNVPQNQI 378

Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVND-NAPRFYTSL-FQESVSENVPIG-YSIVRVQ 280
           ++ ++  D G P  + T + +I +   +D +A   Y  +  +E  S     G  +  +  
Sbjct: 379 QIEVKCTDSGQPFENATQKFVIYLIMYDDYHASITYRPISVKEDASVGTTAGTLTATQSL 438

Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS--GWVYTSGQLDRETQAKYQLLVTA 338
           A      +N  L  T+ +K   G     IT D  +    +    +LD E ++ +    +A
Sbjct: 439 ALPVTLSIN-HLNNTVLEKFKIGATTCSITADTATCTADILVKSELDFEDKSTFTFTASA 497

Query: 339 T-DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397
               G   R  T T              ++ G   V   E+   G  V +   TD D+  
Sbjct: 498 NFSKGVVTREFTITVKNVNEAPTDI---YLNGTLTVP--ENAVAGAIVGSFLVTDPDKTQ 552

Query: 398 RLHYE-ITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMV 455
             +   +    + G    T +NG  L    +P +++++ R   + V+ TD G  + +   
Sbjct: 553 THNCSLVNSAQSTGSSYFTVENGTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNLSTTK 612

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
             NIT  N   P  + +  + +V E++P+GT V  +S  + D   N   T+++ S+    
Sbjct: 613 DFNITVTNQNEPPLQVSITSQTVPENSPLGTLVGSLSCEEPDKLTNDNCTFTIDSQ---- 668

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
                +  F +     ++  N  LD E      + V A D G   L     ++I++ D N
Sbjct: 669 -----NYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKG--GLYKKVKLQINITDQN 721

Query: 576 D-----NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           D     N P     L   ++ E++  GT +S +   D D          L     + G  
Sbjct: 722 DAPTGINLPGNGGDL---SVYENSRSGTVISAIKLVDQD---GDPPSCSLTD---DAGGR 772

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
           V    + +I  +   D E  A   +     DG    QS     +I ++D+N+ P   +  
Sbjct: 773 VAVQGTNLITGSANSDFEESAVLHITLSCSDGKV--QSIQKSFNITVKDVNEVPT--DIT 828

Query: 691 CLTFYISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIKGG--DDSNSFSLETRQGSDKA 746
                + EN    T IG I   DPD  +     V   I  G  D S  F ++     ++ 
Sbjct: 829 LSHRQVLENE-ANTRIGIITVTDPDVNQSHRCTVCDVIDEGRCDASADFIVD-----ERL 882

Query: 747 ELVTMVDLDYESPRKKYELVI----RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
           +L+T   LD+ES   +  +VI     A SP +   V     +T ++ N P        F 
Sbjct: 883 QLLTSRGLDFESGHIR-RIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFE 941

Query: 803 NYKDCFPVGPFGRVPAYDAD----VTDKLQYRILSGN 835
                       R+ A D D    V   L Y+I++G+
Sbjct: 942 QAIRASVGSVVARLSAVDPDNAGSVKQALTYKIITGS 978



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 48/197 (24%), Positives = 84/197 (42%), Gaps = 12/197 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F +D R   LLT   LD E      +++  TD A+     LS     ++ +ID N+  P 
Sbjct: 876  FIVDERL-QLLTSRGLDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNE--PP 932

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGA-NSAIRYAIIGGNTQMQFSIDSLSG 207
             S    +   ++ I  +   V+A++ A D D  G+   A+ Y II G+    F +     
Sbjct: 933  TS--VCSSPFEQAIRASVGSVVARLSAVDPDNAGSVKQALTYKIITGSGVFPFQLFK--- 987

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
               + KT D  Q  ++   I+  D G   +  +   L  N+   N        ++  + +
Sbjct: 988  -NMIFKTADVIQPTNFTFSIQVTDDGRVVTDVSPNGLTFNVSKPNTVVFNCSLAVTADFM 1046

Query: 267  SENVPIGYSIVRVQAYD 283
            S+ + +  S+V VQ+ D
Sbjct: 1047 SDALDLRPSVVSVQSRD 1063



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 112/528 (21%), Positives = 184/528 (34%), Gaps = 41/528 (7%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            FR+     ++L   SLD E      ++V ATD+       L     + +NI D ND    
Sbjct: 672  FRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGG-----LYKKVKLQINITDQNDAPTG 726

Query: 150  FSEKTYTVSVDEDISVTDN----PVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
             +          D+SV +N     VI+ IK  D D    S       GG   +Q   + +
Sbjct: 727  IN----LPGNGGDLSVYENSRSGTVISAIKLVDQDGDPPSCSLTDDAGGRVAVQ-GTNLI 781

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            +G  +     D+E+     + +   DG   S   +    I ++DVN+  P   T   ++ 
Sbjct: 782  TGSAN----SDFEESAVLHITLSCSDGKVQSIQKSFN--ITVKDVNE-VPTDITLSHRQV 834

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--LPITIDPRSGWVYTSGQ 323
            +         I+ V     D  VN     T+ D    G  D      +D R   + TS  
Sbjct: 835  LENEANTRIGIITV----TDPDVNQSHRCTVCDVIDEGRCDASADFIVDERL-QLLTSRG 889

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAEDEPPG 382
            LD E+    ++++  TD    P+   +                        E A     G
Sbjct: 890  LDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFEQAIRASVG 949

Query: 383  TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            + V  L+A D D    +   +T     G      Q  + +I   +  D  Q   +  ++ 
Sbjct: 950  SVVARLSAVDPDNAGSVKQALTYKIITGSGVFPFQLFKNMI--FKTADVIQPTNFTFSIQ 1007

Query: 443  ATDSGG-RSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
             TD G   +D +   +    +     VF  +   TA    DA +     VVS    D  +
Sbjct: 1008 VTDDGRVVTDVSPNGLTFNVSKPNTVVFNCSLAVTADFMSDA-LDLRPSVVSVQSRDNSL 1066

Query: 501  NAQITYSLSSEISNEA---VAHHDQ--QFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
              ++  SL  +  NE    + + D+   F IN     + +  + D   +          D
Sbjct: 1067 IGRL--SLPKKFPNETFKYLLNSDETVPFAINGDQVFVKSIAMKDYALIFENKSAFVYLD 1124

Query: 556  GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
                S       E   V ++D+ P  K  L   +I E    G+ V Q+
Sbjct: 1125 INAESSQGVNRSEGHFVKISDDVPEMKMCLVKKSIEEKKPQGSIVGQL 1172


>SB_35194| Best HMM Match : EGF_2 (HMM E-Value=0)
          Length = 960

 Score = 70.1 bits (164), Expect = 2e-11
 Identities = 70/249 (28%), Positives = 91/249 (36%), Gaps = 28/249 (11%)

Query: 1494 AQSLLNRPTVRENVRD-GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS-A 1551
            A S L  PT +  + D  C S A C     P  S  +   +S  C C  G  G  C    
Sbjct: 79   AASGLELPTRKPCIGDRNCGSNAACH----PNQSGRIEKKES--CYCLPGYHGDGCQHYG 132

Query: 1552 CELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACD 1610
            C   PC     C        + CAC PG+   T  C    +  CP G WG    G C C 
Sbjct: 133  CTPNPCQNGGTCKQSLQNGSFVCACAPGFHGNT--C----QLPCPDGQWGIDCKGVCTCS 186

Query: 1611 VTRGYHPHCNKENGKCHCKENHYKPEGTAEC------LPCQCYAAGSENSSCEAATGQCH 1664
                 +  C+   GKCHC   +  P    EC        C         +SC+  TG C+
Sbjct: 187  E----YGSCDSRTGKCHCMPGYSGPTCIDECPTGYYGYECTQKCQCVNGASCDRRTGSCN 242

Query: 1665 CRPGVIGRAC-DACA-NAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDC-P 1721
            C  G IG+ C   C  N + E      C     G   S+     + +T    + + DC  
Sbjct: 243  CTVGWIGKFCQQTCPHNTWGEGYCKEECPRGIYGRNCSYTCQCAYNQTCSKRDGLCDCRV 302

Query: 1722 PGSSGRATR 1730
            PG +G   R
Sbjct: 303  PGVTGVTCR 311



 Score = 68.1 bits (159), Expect = 9e-11
 Identities = 55/179 (30%), Positives = 76/179 (42%), Gaps = 33/179 (18%)

Query: 1520 SICPP--YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGY------ 1571
            S CP   +S    +  +  C C  G  G  C+ AC +G  G       Q   GY      
Sbjct: 541  SPCPKCYHSNGACNAATGKCVCLDGYHGDSCLEACSVGYFGRQCQSKCQCLHGYCDHVTG 600

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            SC C PG+T     C ++    CP G +G +   PCAC      +  CN  +G C+C   
Sbjct: 601  SCECLPGWT--GKRCDQA----CPSGTYGFNCTLPCAC-----VNGSCNATDGSCNCAAG 649

Query: 1632 HYK-------PEGT--AEC-LPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
            ++        P G   A C L C C    + N +C A TG+C C  G  G +C+A  +A
Sbjct: 650  YHGNACDRPCPAGKHGANCGLKCLC----ANNGTCNAITGRCSCGTGWTGPSCNASCSA 704



 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 47/194 (24%), Positives = 62/194 (31%), Gaps = 24/194 (12%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTL 1581
            CP  +       S  C+C  G  GP C   C     G     P     G  C    G   
Sbjct: 327  CPCMNGAECDRVSGVCSCSPGWTGPFCSKPCPPSLWGHNCAHPCNCTNGARCNAVTGQCA 386

Query: 1582 TTSGCIESGKEECPGGWWGGSACGPCACD---------VTRGYHPHCNKENGKCHCKENH 1632
             T GC       C  GW G     PC  D              +  C+  +G+C C    
Sbjct: 387  CTDGC------SCNAGWTGPECRDPCGLDSWGPGCTNTCQCSRNGECDAASGRCACAPGF 440

Query: 1633 YKPEGTAEC------LPCQ--CYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAE 1683
                  + C        C   C    +  + C+  +G CHC PG  GR+C   C      
Sbjct: 441  TGDRCESRCPKGYYGTNCSNACTCKATNTNVCDVTSGFCHCNPGWSGRSCYQPCPGGSWG 500

Query: 1684 VTPNSGCEVVYDGC 1697
            V  +S C+ +   C
Sbjct: 501  VNCSSKCDCINGSC 514



 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 54/166 (32%), Positives = 69/166 (41%), Gaps = 31/166 (18%)

Query: 1539 CEAGRVGPQCVSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597
            C AG  G  C   C   PC   A C  D+   G  C+C PG+T    G   S  + CP  
Sbjct: 314  CRAGFFGIDCNHKC---PCMNGAEC--DRV-SGV-CSCSPGWT----GPFCS--KPCPPS 360

Query: 1598 WWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTA--ECL-PCQCYAAG---- 1650
             WG +   PC C  T G    CN   G+C C +      G    EC  PC   + G    
Sbjct: 361  LWGHNCAHPCNC--TNG--ARCNAVTGQCACTDGCSCNAGWTGPECRDPCGLDSWGPGCT 416

Query: 1651 -----SENSSCEAATGQCHCRPGVIGRACDA-CANAYAEVTPNSGC 1690
                 S N  C+AA+G+C C PG  G  C++ C   Y     ++ C
Sbjct: 417  NTCQCSRNGECDAASGRCACAPGFTGDRCESRCPKGYYGTNCSNAC 462



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 26/166 (15%)

Query: 1537 CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPG 1596
            C+C  G  GP C ++C  G  G             +C   PG+T    G  +S K+ CP 
Sbjct: 687  CSCGTGWTGPSCNASCSAGRYGI------------NCVARPGWT----G--KSCKDPCPA 728

Query: 1597 GWWGGSACGPCACDVTR-GYHPHCNKENGKCHCKENHYKPEGTAECLP------CQCYAA 1649
            G +G      C CD ++      C+   G+C+C+  +  P    +C        C     
Sbjct: 729  GRYGMMCASSCRCDPSKTDVKKPCDHVTGQCNCRPGYRGPRCLEQCPEGRYGDQCARKCE 788

Query: 1650 GSENSSCEAATGQCHCRPGVIGRACD-ACANAYAEVTPNSGCEVVY 1694
                  C A  G C C PG  G +C   C         +S C+ V+
Sbjct: 789  CDNRVPCRATDGVCLCLPGYYGNSCQLMCPRDRYGFNCSSTCQCVH 834



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 48/178 (26%), Positives = 63/178 (35%), Gaps = 37/178 (20%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570
            C S+ DC+   C P +          C C     G +C   C        +C        
Sbjct: 503  CSSKCDCINGSCDPVT--------GACVCNRRVTGQRCDKPCINCNSPCPKCYHSNGACN 554

Query: 1571 YS---CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627
             +   C C  GY      C+E+    C  G++G      C C      H +C+   G C 
Sbjct: 555  AATGKCVCLDGYH--GDSCLEA----CSVGYFGRQCQSKCQC-----LHGYCDHVTGSCE 603

Query: 1628 C-------KENHYKPEGTA--EC-LPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
            C       + +   P GT    C LPC C      N SC A  G C+C  G  G ACD
Sbjct: 604  CLPGWTGKRCDQACPSGTYGFNCTLPCACV-----NGSCNATDGSCNCAAGYHGNACD 656



 Score = 51.6 bits (118), Expect = 9e-06
 Identities = 47/190 (24%), Positives = 66/190 (34%), Gaps = 29/190 (15%)

Query: 1511 CQSRADCMLSICPPYS---KCVTSWDSSTC--TCEAGRVGPQCV--SACELGPC----GA 1559
            CQS+  C+   C   +   +C+  W    C   C +G  G  C    AC  G C    G+
Sbjct: 584  CQSKCQCLHGYCDHVTGSCECLPGWTGKRCDQACPSGTYGFNCTLPCACVNGSCNATDGS 643

Query: 1560 ARCVPDQTPKGYSCACEPGYTLTTSG----CIESG-------KEECPGGWWGGSACGPCA 1608
              C            C  G      G    C  +G       +  C  GW G S    C+
Sbjct: 644  CNCAAGYHGNACDRPCPAGKHGANCGLKCLCANNGTCNAITGRCSCGTGWTGPSCNASCS 703

Query: 1609 CD---VTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSE-NSSCEAATGQCH 1664
                 +     P    ++ K  C    Y   G      C+C  + ++    C+  TGQC+
Sbjct: 704  AGRYGINCVARPGWTGKSCKDPCPAGRY---GMMCASSCRCDPSKTDVKKPCDHVTGQCN 760

Query: 1665 CRPGVIGRAC 1674
            CRPG  G  C
Sbjct: 761  CRPGYRGPRC 770



 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 45/150 (30%), Positives = 60/150 (40%), Gaps = 23/150 (15%)

Query: 1537 CTCEAGRVGPQCVSACELGPCG---AARC-----VPDQTPKGYSCACEPGYTLTTSGCIE 1588
            C C  G  GP+C+  C  G  G   A +C     VP +   G  C C PGY    + C  
Sbjct: 759  CNCRPGYRGPRCLEQCPEGRYGDQCARKCECDNRVPCRATDGV-CLCLPGYY--GNSC-- 813

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK---CHCKENHYKPEGTAECLPCQ 1645
              +  CP   +G +    C C    G    C+K++G      C EN   P+GT     C 
Sbjct: 814  --QLMCPRDRYGFNCSSTCQC--VHGNTRMCDKKDGSYVGVLC-ENRC-PQGTYGP-GCH 866

Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
                    + C+  TG C C  G  G+ CD
Sbjct: 867  NNCTCLNGAQCDHVTGTCTCPVGYKGKYCD 896



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 42/168 (25%), Positives = 57/168 (33%), Gaps = 22/168 (13%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCT--CEAGRVGPQCVSACELGPCGAARCVPDQTP 1568
            C +R  C  +       C+  +  ++C   C   R G  C S C+        C  D+  
Sbjct: 789  CDNRVPCRAT--DGVCLCLPGYYGNSCQLMCPRDRYGFNCSSTCQCVHGNTRMC--DKKD 844

Query: 1569 KGY-SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKC 1626
              Y    CE      T G        C  G       G C C V  GY   +C+      
Sbjct: 845  GSYVGVLCENRCPQGTYGPGCHNNCTCLNGAQCDHVTGTCTCPV--GYKGKYCD-----V 897

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
             C +  + P  T  CL C+        + C+  TG C C PG  G  C
Sbjct: 898  ICDKGTFGPGCTQRCL-CE------NGAKCDRKTGACTCAPGFEGLRC 938



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 2/34 (5%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            PC NGAEC  +  + +C C  G TG  C+    P
Sbjct: 328  PCMNGAECDRV--SGVCSCSPGWTGPFCSKPCPP 359


>SB_6200| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 683

 Score = 70.1 bits (164), Expect = 2e-11
 Identities = 54/174 (31%), Positives = 74/174 (42%), Gaps = 31/174 (17%)

Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGA-ARCVPDQTPKGYSCA-CEPG-YTLTTSGCIE-- 1588
            + T  C    +G + +S CE  P G   RC P    +G  C  C+PG Y +T+ GC    
Sbjct: 23   NGTLPCSCDPLGSRTLSECE--PYGGQCRCKPGV--EGRDCGRCKPGFYNMTSEGCRPCD 78

Query: 1589 -----------SGKEECPGGWWGGSACGPCACD------VTRGYHPHCNKENGKCHCKEN 1631
                       SG+ ECP    G + C PC C+      +  G    C       +C + 
Sbjct: 79   CKGPNSVCDPVSGECECPANTVGRT-CEPCQCNNSTDKCLRSGECRDCQHNTTGFYCDKC 137

Query: 1632 HYKPEGTA---ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC-ANAY 1681
                 G A   +C  C C   GS +S C+  TGQC C+  V+GR C  C  N+Y
Sbjct: 138  VTGTYGNATAQQCKACDCNVNGSSSSLCDHVTGQCSCKENVVGRDCSRCKVNSY 191



 Score = 55.2 bits (127), Expect = 7e-07
 Identities = 44/122 (36%), Positives = 57/122 (46%), Gaps = 20/122 (16%)

Query: 1599 WGGSACGPCACDV---------TRGYHPHCNKE--NGKC-HCKENHYK-PEGTAECLPCQ 1645
            +G + C  CAC+V           G  P CN E    KC  CK  ++  P+ T  C  C 
Sbjct: 193  FGPAGCTECACNVHGSASLQCDDSGVCP-CNLEVIGTKCAQCKTGYFGLPKMT--CKACD 249

Query: 1646 CYAAGSENSS-CEAAT-GQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAG 1703
            C   G+ N + C   T GQC C+ GV GRACD C   +   T +SGC V   GC ++   
Sbjct: 250  CNVDGTVNGTVCANDTIGQCQCKSGVTGRACDKCQIYFTGFT-SSGC-VACPGCVKALMK 307

Query: 1704 GV 1705
             V
Sbjct: 308  NV 309



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 1642 LPCQCYAAGSEN-SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
            LPC C   GS   S CE   GQC C+PGV GR C  C   +  +T + GC
Sbjct: 26   LPCSCDPLGSRTLSECEPYGGQCRCKPGVEGRDCGRCKPGFYNMT-SEGC 74


>SB_10656| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1931

 Score = 68.1 bits (159), Expect = 9e-11
 Identities = 53/170 (31%), Positives = 68/170 (40%), Gaps = 21/170 (12%)

Query: 1537 CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPG 1596
            C C    +G QC + C+ G  G   C   Q      C  E G        +    E C  
Sbjct: 658  CQCRPYVIGRQC-NRCKTGYYGFPNCKKCQC---VFCNEETGACDCPPNTVGLNCELCLK 713

Query: 1597 GWWGGS---ACGPCACDV--TRGYHPHCNKENGKCHCKENHYKPE---------GTAECL 1642
            G +G +    C  C CD     G +  CN + G+C CK +H             G   C 
Sbjct: 714  GTFGYNPILGCQDCKCDRFGVAGGNIACNPKTGQCPCKPSHTGRRCDQCAVGYHGYPYCQ 773

Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV--TPNSGC 1690
             C C A G   S C++ TG+C C+ GV G  CD CA  Y  +  T  SGC
Sbjct: 774  QCDCDARGVNGSVCDS-TGRCLCKAGVTGIRCDTCAAGYFNLDNTNPSGC 822



 Score = 67.3 bits (157), Expect = 2e-10
 Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 18/122 (14%)

Query: 1592 EECPGGWWGGSA----CGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTA-------- 1639
            E C  G++G +     C  C C         CN  NG C CK N   P  +         
Sbjct: 1209 ERCRDGYYGDAVVAKNCAKCECSACGAVTSVCNHTNGACQCKANVIGPNCSTCKPNTWNF 1268

Query: 1640 -ECLPCQ-CYAA-GSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDG 1696
              CL C+ C  A  S   SC   TGQC C+PG  GR C+ C   +     N+GC+     
Sbjct: 1269 NSCLGCEDCECAEASLGQSCNVRTGQCLCKPGATGRRCERCKAGFWNY-KNTGCQAC--N 1325

Query: 1697 CP 1698
            CP
Sbjct: 1326 CP 1327



 Score = 55.2 bits (127), Expect = 7e-07
 Identities = 66/232 (28%), Positives = 85/232 (36%), Gaps = 27/232 (11%)

Query: 1516 DCMLSICPP-------YSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQT 1567
            DC L  CP         S+C    D S  C C  G  G QC   C  G  G    VP   
Sbjct: 1090 DCQLCKCPLGTSSNSFASECNVRGDGSLECLCREGYTGDQC-EQCADGYYGDPS-VPGDY 1147

Query: 1568 PKGYSCA--CEPGYTLTTSGCIESGKE-ECPGGWWGGSACGPCACDVTRGYHPHC-NKEN 1623
             K   C    +P  +L     I+   + E        S   P +C+   G    C NK  
Sbjct: 1148 CKKCDCNGNIDPDISLDLKLDIDFSLDLELAIDL---SHQVPGSCNPFTGVCNRCTNKAA 1204

Query: 1624 G-KCH-CKENHYKPEGTAE-CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
            G +C  C++ +Y     A+ C  C+C A G+  S C    G C C+  VIG  C  C   
Sbjct: 1205 GDRCERCRDGYYGDAVVAKNCAKCECSACGAVTSVCNHTNGACQCKANVIGPNCSTCKPN 1264

Query: 1681 YAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTC 1732
                    GCE     C  +  G     RT   +     C PG++GR    C
Sbjct: 1265 TWNFNSCLGCEDC--ECAEASLGQSCNVRTGQCL-----CKPGATGRRCERC 1309



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 41/140 (29%), Positives = 53/140 (37%), Gaps = 29/140 (20%)

Query: 1557 CGAARCVPDQTPK-GYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615
            C     + D+  + G  C C P Y +    C       C  G++G   C  C C      
Sbjct: 641  CDTKGALSDECQEFGGQCQCRP-YVIGRQ-C-----NRCKTGYYGFPNCKKCQC------ 687

Query: 1616 HPHCNKENGKCHCKEN------HYKPEGT------AECLPCQC--YAAGSENSSCEAATG 1661
               CN+E G C C  N          +GT        C  C+C  +     N +C   TG
Sbjct: 688  -VFCNEETGACDCPPNTVGLNCELCLKGTFGYNPILGCQDCKCDRFGVAGGNIACNPKTG 746

Query: 1662 QCHCRPGVIGRACDACANAY 1681
            QC C+P   GR CD CA  Y
Sbjct: 747  QCPCKPSHTGRRCDQCAVGY 766



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 21/53 (39%), Positives = 28/53 (52%)

Query: 1642 LPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVY 1694
            LPC+C   G+ +  C+   GQC CRP VIGR C+ C   Y        C+ V+
Sbjct: 637  LPCECDTKGALSDECQEFGGQCQCRPYVIGRQCNRCKTGYYGFPNCKKCQCVF 689



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 39/137 (28%), Positives = 46/137 (33%), Gaps = 22/137 (16%)

Query: 1606 PCACDVTRGYHPHCNKENGKCHCKE-------NHYKPE--GTAECLPCQCYAAGSENSSC 1656
            PC CD        C +  G+C C+        N  K    G   C  CQC         C
Sbjct: 638  PCECDTKGALSDECQEFGGQCQCRPYVIGRQCNRCKTGYYGFPNCKKCQCVF-------C 690

Query: 1657 EAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPR-SFAGGVWWPRTKFGVE 1715
               TG C C P  +G  C+ C        P  GC+     C R   AGG      K G  
Sbjct: 691  NEETGACDCPPNTVGLNCELCLKGTFGYNPILGCQDC--KCDRFGVAGGNIACNPKTGQ- 747

Query: 1716 TITDCPPGSSGRATRTC 1732
                C P  +GR    C
Sbjct: 748  --CPCKPSHTGRRCDQC 762



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 17/34 (50%), Positives = 20/34 (58%)

Query: 1641 CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            C  C C   GS +  C++ TGQC CRP V GR C
Sbjct: 80   CSGCACDVGGSFDQKCDSITGQCKCRPNVRGRDC 113



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 12/124 (9%)

Query: 1515 ADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACE-----LGPC-GAARCVPDQTP 1568
            A C  S C   +  V +  +  C C+A  +GP C S C+        C G   C   +  
Sbjct: 1226 AKCECSACGAVTS-VCNHTNGACQCKANVIGPNC-STCKPNTWNFNSCLGCEDCECAEAS 1283

Query: 1569 KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRG---YHPHCNKENGK 1625
             G SC    G  L   G      E C  G+W     G  AC+   G       C+   G+
Sbjct: 1284 LGQSCNVRTGQCLCKPGATGRRCERCKAGFWNYKNTGCQACNCPGGPENLWGFCDVNTGQ 1343

Query: 1626 CHCK 1629
            C CK
Sbjct: 1344 C-CK 1346



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 11/28 (39%), Positives = 15/28 (53%)

Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            C  CACDV   +   C+   G+C C+ N
Sbjct: 80   CSGCACDVGGSFDQKCDSITGQCKCRPN 107



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 13/54 (24%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 1622 ENGKC-HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRA 1673
            + G C +C +   + +    C+PC+C      ++ C+  TG+C +C+    G +
Sbjct: 994  DGGSCEYCGKGFTRSDDERTCIPCRC---NGHSNECDPETGECINCQDNTAGNS 1044


>SB_30436| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 633

 Score = 68.1 bits (159), Expect = 9e-11
 Identities = 42/114 (36%), Positives = 63/114 (55%), Gaps = 9/114 (7%)

Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           V A+D   +     + + ITD N+YAPVF+N P T S+ E+ P G TV   +ATD+D   
Sbjct: 239 VYASDGSTQGSLTAI-LTITDVNDYAPVFQNLPLTTSIAENTPTGFTVATATATDADATT 297

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTA 553
           NA IT++++S        + D +F I+  TG IT  K L+ +     Y L ++A
Sbjct: 298 NAVITFAVAS-------GNVDGKFRIDQTTGEITIAKPLEYDNGPKIYTLNISA 344



 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 81/308 (26%), Positives = 130/308 (42%), Gaps = 35/308 (11%)

Query: 488 VLVVSAT-DSDVGINA-QITYSLSSEISN-EAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           VL V+ T D +V I    +  +L  E+S+ E +        ++   G +T NK LDRE  
Sbjct: 46  VLTVNKTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVS--IGELTVNKTLDREVS 103

Query: 545 SGYLLTVTARDGGVPS----LSDTTDVEIS----VVDVNDNEPVFKQQLYTANIMEDALV 596
           SG L+     D  V S    +S T D E+S    +V    +  V   +L  +  ++  + 
Sbjct: 104 SGELIVSKTLDREVSSEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASKTLDREVS 163

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKD------REEGSFVIDPASGVIRTNKALDRESV 650
              ++     D +V     I  +   +D       E+    ID +  ++ T   L     
Sbjct: 164 SGELTVNKTLDREVSSEELIASKTLDRDASKRTEEEQKLLHIDKSYKIVATPSTLALVGT 223

Query: 651 ---------ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
                     +   K  A DG T  Q S   + + I D+ND  PVF++  LT  I+EN+P
Sbjct: 224 IPLAMGFGDGSLRFKVYASDGST--QGSLTAI-LTITDVNDYAPVFQNLPLTTSIAENTP 280

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
            G T+    A D D   NAV+ +++  G+    F ++   G    E+     L+Y++  K
Sbjct: 281 TGFTVATATATDADATTNAVITFAVASGNVDGKFRIDQTTG----EITIAKPLEYDNGPK 336

Query: 762 KYELVIRA 769
            Y L I A
Sbjct: 337 IYTLNISA 344



 Score = 64.9 bits (151), Expect = 9e-10
 Identities = 65/251 (25%), Positives = 108/251 (43%), Gaps = 18/251 (7%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRL-SSTATIHVN---IIDDNDNYPQFS 151
           SG L+   +LDRE  +   ++ K  D+     + + S T    V+   +I       + S
Sbjct: 104 SGELIVSKTLDREVSSEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASKTLDREVS 163

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
               TV+   D  V+   +IA  K  D D    +     ++  +    + I +    ++L
Sbjct: 164 SGELTVNKTLDREVSSEELIAS-KTLDRDASKRTEEEQKLL--HIDKSYKIVATPSTLAL 220

Query: 212 VKTLDYEQV---RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           V T+         S R  + A DG   S   +   ++ I DVND AP F       S++E
Sbjct: 221 VGTIPLAMGFGDGSLRFKVYASDG---STQGSLTAILTITDVNDYAPVFQNLPLTTSIAE 277

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
           N P G+++    A DAD   NA +T+ +     +GNVD    ID  +G +  +  L+ + 
Sbjct: 278 NTPTGFTVATATATDADATTNAVITFAVA----SGNVDGKFRIDQTTGEITIAKPLEYDN 333

Query: 329 QAK-YQLLVTA 338
             K Y L ++A
Sbjct: 334 GPKIYTLNISA 344



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 81/339 (23%), Positives = 132/339 (38%), Gaps = 26/339 (7%)

Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172
           +T+       A P     SS+  + VN   D +      E T   ++D ++S +   +++
Sbjct: 24  HTLTYSLQSNAHPWFRINSSSGVLTVNKTLDRE--VSIGELTVNKTLDREVS-SGELIVS 80

Query: 173 KIKATDADVG---ANSAIRYAIIGGNTQMQFSID-SLSGDVSLV-KTLDYEQVRSYRLVI 227
           K    +  +G    N  +   +  G   +  ++D  +S +  +V KTLD E      +V 
Sbjct: 81  KTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVSSEELIVSKTLDREVSNGELIVS 140

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287
           +  D    S        ++ R+V+        +L +E  SE +    ++ R    DA + 
Sbjct: 141 KTLDREVSSGELIASKTLD-REVSSGELTVNKTLDREVSSEELIASKTLDR----DASKR 195

Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347
              E      DK Y   V  P T+          G  D   + K    V A+DG     S
Sbjct: 196 TEEEQKLLHIDKSYK-IVATPSTLALVGTIPLAMGFGDGSLRFK----VYASDGSTQG-S 249

Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITG 405
            TA                +P      +AE+ P G  V T TATDAD      + + +  
Sbjct: 250 LTAILTITDVNDYAPVFQNLP--LTTSIAENTPTGFTVATATATDADATTNAVITFAVAS 307

Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYVLTVSA 443
           GN  G+F I    G   IT+A+PL++    + Y L +SA
Sbjct: 308 GNVDGKFRIDQTTGE--ITIAKPLEYDNGPKIYTLNISA 344



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 56/208 (26%), Positives = 91/208 (43%), Gaps = 29/208 (13%)

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           GTT+   SAT+ D   N  +TYSL S       AH    F IN  +G +T NK LDRE  
Sbjct: 10  GTTITKFSATNGD---NHTLTYSLQSN------AH--PWFRINSSSGVLTVNKTLDREVS 58

Query: 545 SGYLLTVTARDGGVPS----LSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDALV 596
            G L      D  V S    +S T D E+S+ ++  N+ + ++    +L  +  ++  + 
Sbjct: 59  IGELTVNKTLDREVSSGELIVSKTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVS 118

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI------DPASGVIRTNKALDRESV 650
              +      D +V     I  +   ++   G  +       + +SG +  NK LDRE V
Sbjct: 119 SEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASKTLDREVSSGELTVNKTLDRE-V 177

Query: 651 ATHDL---KAVAIDGGTPPQSSTVIVHI 675
           ++ +L   K +  D     +    ++HI
Sbjct: 178 SSEELIASKTLDRDASKRTEEEQKLLHI 205



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 5/91 (5%)

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNAN 838
           + +TDVND APV ++  +   +  +  P G       A DAD T    + + + SGN   
Sbjct: 254 LTITDVNDYAPVFQNLPLT-TSIAENTPTGFTVATATATDADATTNAVITFAVASGNVDG 312

Query: 839 LILLNETTGSMTLSPQLN-TNVPKLATMEVS 868
              +++TTG +T++  L   N PK+ T+ +S
Sbjct: 313 KFRIDQTTGEITIAKPLEYDNGPKIYTLNIS 343



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 18/52 (34%), Positives = 28/52 (53%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           + + D ND++PVF+      S+ E   +G TV T  ATD D   NA + + +
Sbjct: 254 LTITDVNDYAPVFQNLPLTTSIAENTPTGFTVATATATDADATTNAVITFAV 305



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 51/236 (21%), Positives = 97/236 (41%), Gaps = 16/236 (6%)

Query: 90  FRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASP----VSDRLSSTATI-HVNIIDD 143
           FRI+  SG L    +LDRE  +   TV      + S     VS  L    +I  + +   
Sbjct: 38  FRINSSSGVLTVNKTLDREVSIGELTVNKTLDREVSSGELIVSKTLDREVSIGELTVNKT 97

Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKI---KATDADVGANSAIRYAIIGGNTQMQF 200
            D      E   + ++D ++S ++  +++K    + ++ ++  +  +   +  G      
Sbjct: 98  LDREVSSGELIVSKTLDREVS-SEELIVSKTLDREVSNGELIVSKTLDREVSSGELIASK 156

Query: 201 SIDS--LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
           ++D    SG++++ KTLD E      +  +  D  +  R+   Q L++I           
Sbjct: 157 TLDREVSSGELTVNKTLDREVSSEELIASKTLDRDASKRTEEEQKLLHIDKSYKIVATPS 216

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT--YTMTD-KDYTGNV-DLPIT 310
           T     ++   +  G   +R + Y +D      LT   T+TD  DY     +LP+T
Sbjct: 217 TLALVGTIPLAMGFGDGSLRFKVYASDGSTQGSLTAILTITDVNDYAPVFQNLPLT 272


>SB_7853| Best HMM Match : Cadherin (HMM E-Value=9.9)
          Length = 114

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 42/116 (36%), Positives = 64/116 (55%), Gaps = 10/116 (8%)

Query: 90  FRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           F I  +SG + T   +LDRE    + + V A D+     +      TI V ++D NDN P
Sbjct: 6   FFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGGRTGE-----LTILVFLLDMNDNRP 60

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
           +F++  Y V++ E    T   V+A + ATD D+G+N+ I Y I+GGN    F+ID+
Sbjct: 61  RFTQSVYYVNITE----TTGHVMAGVSATDQDLGSNAVISYRILGGNIDDVFNIDN 112



 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 40/99 (40%), Positives = 56/99 (56%), Gaps = 5/99 (5%)

Query: 523 QFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
           +F I+ Q+G I TT + LDRET   + LTVTA D G    +    + + ++D+NDN P F
Sbjct: 5   KFFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEG--GRTGELTILVFLLDMNDNRPRF 62

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            Q +Y  NI E    G  ++ V ATD D+G N  I Y +
Sbjct: 63  TQSVYYVNITE--TTGHVMAGVSATDQDLGSNAVISYRI 99



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 3/99 (3%)

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469
           G+F I++Q+G  + T  + LD + E  + LTV+A D GGR+    + + + D N+  P F
Sbjct: 4   GKFFISAQSGN-IYTTPENLDRETEDFFNLTVTAMDEGGRTGELTILVFLLDMNDNRPRF 62

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
             + Y  ++ E    G  +  VSATD D+G NA I+Y +
Sbjct: 63  TQSVYYVNITETT--GHVMAGVSATDQDLGSNAVISYRI 99



 Score = 54.8 bits (126), Expect = 9e-07
 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)

Query: 628 GSFVIDPASGVIRTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
           G F I   SG I T  + LDRE+    +L   A+D G      T++V +   D+ND+ P 
Sbjct: 4   GKFFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGGRTGELTILVFLL--DMNDNRPR 61

Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           F      +Y++     G  +  + A D D G NAV+ Y I GG+  + F+++
Sbjct: 62  FTQS--VYYVNITETTGHVMAGVSATDQDLGSNAVISYRILGGNIDDVFNID 111



 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 36/115 (31%), Positives = 60/115 (52%), Gaps = 9/115 (7%)

Query: 199 QFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
           +F I + SG++ +  + LD E    + L + A D G   R+    +L+ + D+NDN PRF
Sbjct: 5   KFFISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGG--RTGELTILVFLLDMNDNRPRF 62

Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
             S++  +++E    G+ +  V A D D G NA ++Y +      GN+D    ID
Sbjct: 63  TQSVYYVNITETT--GHVMAGVSATDQDLGSNAVISYRILG----GNIDDVFNID 111



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)

Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
          +LD ND+ P F    Y  ++ E  ++G  +  + ATDQD+G NA + Y I
Sbjct: 52 LLDMNDNRPRFTQSVYYVNITE--TTGHVMAGVSATDQDLGSNAVISYRI 99



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 3/105 (2%)

Query: 311 IDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
           I  +SG +YT+ + LDRET+  + L VTA D G   R+   T              F   
Sbjct: 8   ISAQSGNIYTTPENLDRETEDFFNLTVTAMDEGG--RTGELTILVFLLDMNDNRPRFTQS 65

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414
            Y V + E        V+ T  D   +  + Y I GGN    F+I
Sbjct: 66  VYYVNITETTGHVMAGVSATDQDLGSNAVISYRILGGNIDDVFNI 110


>SB_32515| Best HMM Match : FAINT (HMM E-Value=4.5)
          Length = 103

 Score = 67.3 bits (157), Expect = 2e-10
 Identities = 29/82 (35%), Positives = 47/82 (57%)

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           +D    A + L   A D G P  +S+  VH+ ++DIND+ P+F     +F + E++ +  
Sbjct: 18  IDNNGKAVYSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAH 77

Query: 705 TIGEIRAHDPDEGPNAVVHYSI 726
           T+G++ A D D G NA + YSI
Sbjct: 78  TVGKVTAEDKDWGINARLSYSI 99



 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 35/100 (35%), Positives = 56/100 (56%), Gaps = 9/100 (9%)

Query: 531 GAITTNKLLDRET---------MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
           GA+T + L DRE           + Y L V A D G P+++ +  V + V D+NDN P+F
Sbjct: 1   GALTWSNLFDREKPLLKIDNNGKAVYSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIF 60

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
            + +Y+  + EDA +  +V +V A D D G+N R+ Y ++
Sbjct: 61  SKTVYSFTVKEDAQLAHTVGKVTAEDKDWGINARLSYSIN 100



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 5/87 (5%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           +D    A Y++LV+A D  +P    ++S+AT+HV + D NDN P FS+  Y+ +V ED  
Sbjct: 18  IDNNGKAVYSLLVEAADHGNPT---MTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQ 74

Query: 165 VTDNPVIAKIKATDADVGANSAIRYAI 191
           +     + K+ A D D G N+ + Y+I
Sbjct: 75  LAH--TVGKVTAEDKDWGINARLSYSI 99



 Score = 58.8 bits (136), Expect = 6e-08
 Identities = 23/74 (31%), Positives = 49/74 (66%)

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
           Y L++ A D G+P+ +++  + + + D+NDN+P F  +++  +V E+  + +++ +V A 
Sbjct: 26  YSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAE 85

Query: 283 DADEGVNAELTYTM 296
           D D G+NA L+Y++
Sbjct: 86  DKDWGINARLSYSI 99



 Score = 56.0 bits (129), Expect = 4e-07
 Identities = 30/75 (40%), Positives = 45/75 (60%), Gaps = 2/75 (2%)

Query: 437 YVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           Y L V A D G  + T  A V + + D N+ +P+F    Y+ +V EDA +  TV  V+A 
Sbjct: 26  YSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAE 85

Query: 495 DSDVGINAQITYSLS 509
           D D GINA+++YS++
Sbjct: 86  DKDWGINARLSYSIN 100



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 20/48 (41%), Positives = 28/48 (58%)

Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
          D ND+SP+F    Y  +V+E A    TV  + A D+D G NA + Y+I
Sbjct: 52 DINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAEDKDWGINARLSYSI 99



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 763 YELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
           Y L++ AA   +P + +   V +LV D+NDN+P+       F   +D       G+V A 
Sbjct: 26  YSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLAHTVGKVTAE 85

Query: 820 DAD--VTDKLQYRI 831
           D D  +  +L Y I
Sbjct: 86  DKDWGINARLSYSI 99



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           ++D   +A Y LLV A D G+P  +++AT              F    Y   + ED    
Sbjct: 17  KIDNNGKAVYSLLVEAADHGNPTMTSSATVHVLVDDINDNSPIFSKTVYSFTVKEDAQLA 76

Query: 383 TPVVTLTATDAD--EDNRLHYEI 403
             V  +TA D D   + RL Y I
Sbjct: 77  HTVGKVTAEDKDWGINARLSYSI 99


>SB_29802| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 546

 Score = 65.7 bits (153), Expect = 5e-10
 Identities = 47/148 (31%), Positives = 65/148 (43%), Gaps = 22/148 (14%)

Query: 1533 DSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592
            ++ +C C+    G +C   C  G  G   C+         CAC      T   C + G+ 
Sbjct: 62   NTGSCVCKDNFQGHRC-QKCMTGYYGFPLCI--------KCACSNSGFGT---CGQYGEC 109

Query: 1593 ECPGGWWGGSACGPCACDVTRGYH--PHCNKENGKCHCKENHYKPEGTAECLPCQCYAAG 1650
             C  G+ G S C  CA    +G++  PHC  E G     EN      +     C C   G
Sbjct: 110  ICRPGYTGRS-CESCA----KGFYGFPHCTGEYG---LSENGIPVVNSITVATCNCNVQG 161

Query: 1651 SENSSCEAATGQCHCRPGVIGRACDACA 1678
            SE+ SC+ A+G+C C+  VIG  CD CA
Sbjct: 162  SESQSCDQASGKCTCKKNVIGWKCDMCA 189



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 40/139 (28%), Positives = 54/139 (38%), Gaps = 22/139 (15%)

Query: 1552 CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV 1611
            C   P GA   V DQ+     C C     +    C     + CP G +    C  C CD 
Sbjct: 2    CNCNPEGATNLVCDQSTG--RCPCRT--RIRGKKC-----DLCPLGHFNFPRCKGCDCDP 52

Query: 1612 TRGYHPHCNKENGKCHCKENHYKPE---------GTAECLPCQCYAAGSENSSCEAATGQ 1662
                   C+   G C CK+N              G   C+ C C  +G    +C    G+
Sbjct: 53   LTTKDEICDN-TGSCVCKDNFQGHRCQKCMTGYYGFPLCIKCACSNSGF--GTC-GQYGE 108

Query: 1663 CHCRPGVIGRACDACANAY 1681
            C CRPG  GR+C++CA  +
Sbjct: 109  CICRPGYTGRSCESCAKGF 127



 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 53/197 (26%), Positives = 70/197 (35%), Gaps = 27/197 (13%)

Query: 1521 ICPPYSKCVT--SWDSSTCT-CEAGRVG-PQCVS-ACE---LGPCGA-ARCVPDQTPKGY 1571
            IC     CV   ++    C  C  G  G P C+  AC     G CG    C+      G 
Sbjct: 59   ICDNTGSCVCKDNFQGHRCQKCMTGYYGFPLCIKCACSNSGFGTCGQYGECICRPGYTGR 118

Query: 1572 SC-ACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            SC +C  G+        E G  E             C C+V       C++ +GKC CK+
Sbjct: 119  SCESCAKGFYGFPHCTGEYGLSENGIPVVNSITVATCNCNVQGSESQSCDQASGKCTCKK 178

Query: 1631 N--HYKPEGTAE-------CLPCQCYAAGS------ENSSCEAATGQCHCRPGVIGRACD 1675
            N   +K +  A+       C  C C   G+          C  A   C C+  V G  CD
Sbjct: 179  NVIGWKCDMCAKDLVSFPACTKCNCDPGGTVVLPGQSKVGCFGAKQSCMCKMNVQGTLCD 238

Query: 1676 ACANAYAEVTPN--SGC 1690
             C   Y   +    SGC
Sbjct: 239  RCRFGYFNFSAENPSGC 255



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 16/48 (33%), Positives = 24/48 (50%)

Query: 1644 CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691
            C C   G+ N  C+ +TG+C CR  + G+ CD C   +       GC+
Sbjct: 2    CNCNPEGATNLVCDQSTGRCPCRTRIRGKKCDLCPLGHFNFPRCKGCD 49



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 37/150 (24%), Positives = 51/150 (34%), Gaps = 25/150 (16%)

Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593
            S  CTC+   +G +C   C         C          C C+PG T+   G     K  
Sbjct: 171  SGKCTCKKNVIGWKC-DMCAKDLVSFPACT--------KCNCDPGGTVVLPG---QSKVG 218

Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653
            C G      A   C C +       C++    C     ++  E  + C  C C   G+  
Sbjct: 219  CFG------AKQSCMCKMNV-QGTLCDR----CRFGYFNFSAENPSGCTTCGCSTRGTMA 267

Query: 1654 S--SCEAATGQCHCRPGVIGRACDACANAY 1681
            +   C   TG C C+  V G    A A  Y
Sbjct: 268  AMRGCHHVTGICSCKNYVTGSKLTASARVY 297


>SB_8046| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1304

 Score = 64.9 bits (151), Expect = 9e-10
 Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 27/179 (15%)

Query: 1537 CTCEAGRVGP--QCVSACELGPCGAAR-CVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593
            C   AG  G   Q   ACE    GA    V DQ   G  C+C P         I    +E
Sbjct: 679  CQVLAGFYGDLYQKGQACECNATGAVTPSVCDQC--GGQCSCRPHV-------IGRKCDE 729

Query: 1594 CPGGWW---GGSACGPCACDVTRGYHPHCNKENGKCHCK------------ENHYKPEGT 1638
            C   ++    G  C  CAC++T      C+ + GKC C             ++++     
Sbjct: 730  CRPDYYDFTSGLGCKACACNMTGSKRSSCHPDTGKCECHPSITERQCSRCLDHYFNFTSG 789

Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGC 1697
              C PC C    S +  C+  TG C C+ GV G  C  C++A+  +T   G  +    C
Sbjct: 790  VGCQPCGCNELYSRDLQCDNDTGVCSCKDGVGGAKCTECSDAFYNLTLKVGSHLPVGQC 848



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 6/61 (9%)

Query: 1637 GTAECLPCQCYAAG----SENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNS--GC 1690
            G A  + C C   G      N+ C A TG+C C+P V GRACD C +    ++  S  GC
Sbjct: 290  GLAVFIDCACTLTGVRNMPNNTECNAVTGECDCKPNVQGRACDTCKDTMWNISNTSPQGC 349

Query: 1691 E 1691
            +
Sbjct: 350  Q 350



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 18/37 (48%), Positives = 19/37 (51%)

Query: 1641 CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC 1677
            C  CQC   GS N  C    G C CR   IGR CD+C
Sbjct: 894  CTGCQCDLNGSLNPVCNKLNGNCTCRSNAIGRLCDSC 930



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 1/44 (2%)

Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
            TA C  C C  AGS N +C    G CHCRP   G  CD     +
Sbjct: 430  TAGCSACNCDPAGSINVTCSDG-GACHCRPHFSGLKCDVIERGF 472



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/28 (46%), Positives = 16/28 (57%)

Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            C  C CD+    +P CNK NG C C+ N
Sbjct: 894  CTGCQCDLNGSLNPVCNKLNGNCTCRSN 921



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 11/27 (40%), Positives = 14/27 (51%)

Query: 1663 CHCRPGVIGRACDACANAYAEVTPNSG 1689
            C C    +G+ C+ CA  Y   TPN G
Sbjct: 1161 CQCPIQYVGQFCERCAPGYTRATPNGG 1187


>SB_25851| Best HMM Match : Laminin_G_2 (HMM E-Value=0)
          Length = 683

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 103/398 (25%), Positives = 159/398 (39%), Gaps = 57/398 (14%)

Query: 1111 PVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGP 1170
            P SSF      +      L   F T     LL+Y    +   D+  LEL   + GR    
Sbjct: 35   PKSSFAQHQQWRVSSNGTLTFSFKTFLKDALLIYQD--DGVMDYFNLEL---KVGR---- 85

Query: 1171 GLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLK 1230
             L  +   G   S++T+   + D SWH V I   +  I + LDD  +V+          K
Sbjct: 86   -LLLNIRTGRKTSQVTLGNQLNDLSWHQVSIHVEHVKIGLTLDDHTRVV----------K 134

Query: 1231 YACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISD--F 1288
                N   K  P+R          F  L   L I  L + P+   V  K F GCI D   
Sbjct: 135  IPRKNLALKNNPSRYLY-------FGGLPRSLSISTL-SFPAV--VFAKRFTGCIKDVEI 184

Query: 1289 YIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAEC-SDLWDTYICDCK-EGHTGK 1346
             I +   +    V   G + GC   R+ C S PC NG  C + +W +  CDC   G  G 
Sbjct: 185  QIGNGVQEELRLVESKGRVRGC---RNACRSNPCQNGGRCINKIWSS-ACDCSGTGFYGN 240

Query: 1347 DCADSTGPPWRFGGDGMLS----------FNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ 1396
             C +          D ++           ++ ++   +    + + ++T     F++ ++
Sbjct: 241  QCTEEPPRLSMTASDYVIHDMSQEATATFYDHVVIDFRATSSDGIILQTSFASDFLL-VE 299

Query: 1397 LKSGLLHYSYNGETMYLPMA---TLSDGAWHRIEIKWLGTDISVTVDYGLR---TVLMPM 1450
            L  G+L    +     L ++    LSD  WHR EIK    ++ +T+D  L+   T    +
Sbjct: 300  LHRGVLVMQLDIGAGMLKLSIGEKLSDARWHRAEIKRARRNVKLTLDERLKVDGTCPPSL 359

Query: 1451 LANKIQGQYIGKILIGGL-DTTAGLLASDVGFFEGCIQ 1487
             A  +QG   G++ IGG+ D T    +     FEGCI+
Sbjct: 360  TAFNMQGGE-GRVYIGGVSDPTRSKNSVSRKNFEGCIR 396



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 55/206 (26%), Positives = 84/206 (40%), Gaps = 21/206 (10%)

Query: 1356 WRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSG--LLHYSYNGETMYL 1413
            WR   +G L+F+      +    +AL I          +++LK G  LL+     +T  +
Sbjct: 45   WRVSSNGTLTFS-----FKTFLKDALLIYQDDGVMDYFNLELKVGRLLLNIRTGRKTSQV 99

Query: 1414 PMAT-LSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTA 1472
             +   L+D +WH++ I      I +T+D   R V +P     ++      +  GGL  + 
Sbjct: 100  TLGNQLNDLSWHQVSIHVEHVKIGLTLDDHTRVVKIPRKNLALKNNPSRYLYFGGLPRSL 159

Query: 1473 GLLASD---VGF---FEGCIQDVRI---GTAQSLLNRPTVRENVRDGCQSRADCMLSICP 1523
             +       V F   F GCI+DV I      Q  L     +  VR GC  R  C  + C 
Sbjct: 160  SISTLSFPAVVFAKRFTGCIKDVEIQIGNGVQEELRLVESKGRVR-GC--RNACRSNPCQ 216

Query: 1524 PYSKCVTSWDSSTCTCE-AGRVGPQC 1548
               +C+    SS C C   G  G QC
Sbjct: 217  NGGRCINKIWSSACDCSGTGFYGNQC 242


>SB_552| Best HMM Match : Laminin_EGF (HMM E-Value=1.3e-23)
          Length = 198

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 9/168 (5%)

Query: 1530 TSWDSSTCTCEAGRVGPQCVS-ACELGPCGAARCVP-DQTPKGYSCA-CEPGYTLTTSGC 1586
            TS D   C C  G       + +C LG  G   C    ++  G  C  C+ GY  T +  
Sbjct: 11   TSSDCRECPCPGGPFSANSFARSCVLGSDGLPTCTNCSESHAGRQCERCQDGYYGTPTDP 70

Query: 1587 IESGKEECPGGWWGGSACGPCA-CDVTRGYHPHC--NKENGKCHCKENHYKPEGTAE-CL 1642
            +     +C     G    G    C+ T G    C  N     C    + +    TA+ C 
Sbjct: 71   VNGQCRKCNCN--GNVDPGVTGNCNTTTGECLKCLYNTSGFNCQWCVSGFHGNATAKTCQ 128

Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
             C C   GS++  C   TGQC C P V G +C+ C       T   GC
Sbjct: 129  ACNCTDRGSKHGVCNNVTGQCDCHPLVTGLSCERCVKDAFNYTSGKGC 176



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 50/184 (27%), Positives = 72/184 (39%), Gaps = 39/184 (21%)

Query: 1515 ADCMLSICP--PYS------KCVTSWDS-STCT-CEAGRVGPQCVSACELGPCGAARCVP 1564
            +DC    CP  P+S       CV   D   TCT C     G QC   C+ G  G      
Sbjct: 13   SDCRECPCPGGPFSANSFARSCVLGSDGLPTCTNCSESHAGRQC-ERCQDGYYGTPTDPV 71

Query: 1565 DQTPKGYSCA--CEPGYT----LTTSGCIE-----SGK--EECPGGWWGGSACGPC-ACD 1610
            +   +  +C    +PG T     TT  C++     SG   + C  G+ G +    C AC+
Sbjct: 72   NGQCRKCNCNGNVDPGVTGNCNTTTGECLKCLYNTSGFNCQWCVSGFHGNATAKTCQACN 131

Query: 1611 VT-RGY-HPHCNKENGKCHCK------------ENHYKPEGTAECLPCQCYAAGSENSSC 1656
             T RG  H  CN   G+C C             ++ +       C  C C+  GS ++ C
Sbjct: 132  CTDRGSKHGVCNNVTGQCDCHPLVTGLSCERCVKDAFNYTSGKGCTACGCHPQGSNDTQC 191

Query: 1657 EAAT 1660
            +A +
Sbjct: 192  DAVS 195


>SB_49286| Best HMM Match : Laminin_N (HMM E-Value=0)
          Length = 1465

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 24/46 (52%), Positives = 30/46 (65%), Gaps = 3/46 (6%)

Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678
            + P+G   C PC C   GS N++C   TGQCHC+PGV GR CD C+
Sbjct: 1025 FPPKG---CEPCNCDTTGSWNNTCSVTTGQCHCKPGVTGRRCDQCS 1067



 Score = 62.5 bits (145), Expect = 5e-09
 Identities = 39/128 (30%), Positives = 56/128 (43%), Gaps = 16/128 (12%)

Query: 1621 KENGKCHCKENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676
            K N    CK+ + +  G+    A+C+PCQCY     + +C+  TG+C+C+    G  CD 
Sbjct: 679  KGNNCEQCKDGYTRQAGSTDRYAQCVPCQCYG---HSDTCDPVTGKCNCKHNTTGIRCDK 735

Query: 1677 CANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETI-TDCPPGSSGRATRTCDET 1735
            C + Y    P  G       CP  F         + G   + TDCP G  G     CD  
Sbjct: 736  CIDGYYG-NPTQGTPDDCKKCPCKFGTRC----IQIGANVVCTDCPEGHVG---NLCDMC 787

Query: 1736 KDVPWQDP 1743
            +D  + DP
Sbjct: 788  QDGYYGDP 795



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 5/71 (7%)

Query: 1625 KCH-CKENHYKPEGTAECLPCQCYAAGSENSSCEA-ATGQCHCRPGVIGRACDACANAY- 1681
            KC  C+ N++    T  C PCQC+  G++ +  +    G+C C+  V+G  C  C + Y 
Sbjct: 400  KCDKCQANYFGFSQTG-CRPCQCFGPGTDPAKTQCNEKGECTCKRHVVGAKCTLCRSGYF 458

Query: 1682 -AEVTPNSGCE 1691
              E +   GC+
Sbjct: 459  GLEASNPHGCK 469



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 13/66 (19%)

Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKE------------NHYKPEGTAECLPCQCYAAGS 1651
            C PC CD T  ++  C+   G+CHCK             +HY       CL C C   GS
Sbjct: 1030 CEPCNCDTTGSWNNTCSVTTGQCHCKPGVTGRRCDQCSIDHY-AFSELGCLACNCNLQGS 1088

Query: 1652 ENSSCE 1657
             N +C+
Sbjct: 1089 LNVTCD 1094



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 19/133 (14%)

Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKEN 1623
            P+Q      C+C   Y        + G     G     + C PC C    G+   C+   
Sbjct: 663  PNQVNWVEQCSCPKEYKGNNCEQCKDGYTRQAGSTDRYAQCVPCQC---YGHSDTCDPVT 719

Query: 1624 GKCHCKEN------------HY--KPEGTA-ECLPCQCYAAGSENSSCEAATGQCHCRPG 1668
            GKC+CK N            +Y    +GT  +C  C C   G+      A      C  G
Sbjct: 720  GKCNCKHNTTGIRCDKCIDGYYGNPTQGTPDDCKKCPC-KFGTRCIQIGANVVCTDCPEG 778

Query: 1669 VIGRACDACANAY 1681
             +G  CD C + Y
Sbjct: 779  HVGNLCDMCQDGY 791



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 45/179 (25%), Positives = 60/179 (33%), Gaps = 25/179 (13%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCT-CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCA 1574
            DC    C   ++C+    +  CT C  G VG  C   C+ G  G          +G    
Sbjct: 751  DCKKCPCKFGTRCIQIGANVVCTDCPEGHVGNLC-DMCQDGYYG-----DPMGKRGAPTT 804

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHY- 1633
            C+       SG I+           G   C  C  +   G    C       +    HY 
Sbjct: 805  CQK---CNCSGNIDPNAIGSCDRLTGD--CLKCIHNTRNGPISQCELCAIGYYGNATHYP 859

Query: 1634 KPEGTAECLPCQCYAAGSENSSCEAAT--------GQCHCRPGVIGRACDACANAYAEV 1684
            KP+    C  C+CY  G+ +      T        G+C C P V G  CD C   Y  V
Sbjct: 860  KPQ----CKACECYVQGTVSPPGHDPTLPFPCDDKGRCTCLPNVSGDKCDTCRPEYWNV 914



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 1654 SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
            S C +  GQC C+PGV G  CD C   Y   +  +GC
Sbjct: 382  SDCNSE-GQCRCKPGVTGIKCDKCQANYFGFS-QTGC 416



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 13/33 (39%), Positives = 15/33 (45%), Gaps = 1/33 (3%)

Query: 1317 CSSAPCYNGAECSDLWDTYIC-DCKEGHTGKDC 1348
            C   PC  G  C  +    +C DC EGH G  C
Sbjct: 752  CKKCPCKFGTRCIQIGANVVCTDCPEGHVGNLC 784


>SB_22952| Best HMM Match : EGF_2 (HMM E-Value=2e-23)
          Length = 300

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 49/176 (27%), Positives = 67/176 (38%), Gaps = 15/176 (8%)

Query: 1534 SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593
            + TC+C+ G  G  C   C  G  G             +C+   G    TSG      E+
Sbjct: 115  NGTCSCQTGWTGENCDITCSQGRWGVGCQGTCDCKNNATCSPFTGQCNCTSGFTGDRCEK 174

Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP------CQCY 1647
               G  GG  C    C+ T      CN   GKC C+   Y  +  AEC        C  +
Sbjct: 175  QCAGDSGGVDCRQ-HCNCTEW--GTCNPFTGKCLCQSGFYGEDCGAECPDGTYGPACTAH 231

Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANAY---AEVT---PNSGCEVVYDGC 1697
                +N++C+   G C C+PG  G  C+     Y    E T    N+ C+VV   C
Sbjct: 232  CKCQKNATCDKIDGTCQCKPGWTGIDCECSPGKYGNKCEKTCSCNNNYCDVVTGVC 287



 Score = 54.8 bits (126), Expect = 9e-07
 Identities = 49/174 (28%), Positives = 65/174 (37%), Gaps = 25/174 (14%)

Query: 1510 GCQSRADCMLSI-CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTP 1568
            GCQ   DC  +  C P++          C C +G  G +C   C  G  G   C      
Sbjct: 141  GCQGTCDCKNNATCSPFT--------GQCNCTSGFTGDRCEKQCA-GDSGGVDCRQHCNC 191

Query: 1569 KGYSCACEP--GYTLTTSGCI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625
              +   C P  G  L  SG   E    ECP G +G +    C C      +  C+K +G 
Sbjct: 192  TEWG-TCNPFTGKCLCQSGFYGEDCGAECPDGTYGPACTAHCKCQK----NATCDKIDGT 246

Query: 1626 CHCKENHYKPEGTAECLPCQ----CYAAGS-ENSSCEAATGQCHCRPGVIGRAC 1674
            C CK      +   EC P +    C    S  N+ C+  TG C+C  G     C
Sbjct: 247  CQCKPGWTGID--CECSPGKYGNKCEKTCSCNNNYCDVVTGVCNCPHGYERPTC 298


>SB_42841| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1651

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 30/67 (44%), Positives = 39/67 (58%), Gaps = 3/67 (4%)

Query: 1640 ECLPCQCYAAGSENSS-CEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCP 1698
            EC PC C   GS NSS C+  TGQC C+PGV G+ CD C+  +   T ++GC +  D C 
Sbjct: 16   ECQPCACNKTGSYNSSTCDRETGQCKCKPGVAGQNCDRCSVQHVNFT-DTGC-IACDICT 73

Query: 1699 RSFAGGV 1705
            R    G+
Sbjct: 74   RLGLQGI 80



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 13/27 (48%), Positives = 18/27 (66%), Gaps = 1/27 (3%)

Query: 1604 CGPCACDVTRGYHPH-CNKENGKCHCK 1629
            C PCAC+ T  Y+   C++E G+C CK
Sbjct: 17   CQPCACNKTGSYNSSTCDRETGQCKCK 43


>SB_52794| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1408

 Score = 62.1 bits (144), Expect = 6e-09
 Identities = 70/264 (26%), Positives = 106/264 (40%), Gaps = 35/264 (13%)

Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDL-WDTYICDCKEGHTGKDCADSTG 1353
            D +     N T   C   ++ C    PC NG  C D+ ++ + CDC  G  G  C +ST 
Sbjct: 887  DFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCIDIGFENFTCDCSAGFGGPLCENST- 945

Query: 1354 PPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS-------IQLKSGLLHYSY 1406
                  G   L+F+      Q  ++ AL  RT   D  ++        +QL+ G +  S 
Sbjct: 946  -TVSLNGSSYLTFD----GSQSEFMVALEFRTTLPDGVLVHDSESKFLLQLREGAIEIS- 999

Query: 1407 NGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466
            NG +     A LSDG W  I +    T   + +     +V +  +  K    +IG  L  
Sbjct: 1000 NGASSAAIEAALSDGNWSGI-VGLNVTQSHLHLSINTSSVSIARINRKNPKLFIGGYL-E 1057

Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVR--DGCQSRADCMLSICPP 1524
             L+    L+        GCI+DV++    S++  P+  E VR   GC     C    C  
Sbjct: 1058 SLEKRRNLI--------GCIRDVKV---NSVVKLPSEMELVRVSMGCPREEVCSPDPC-T 1105

Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQC 1548
               C+  W +  C C+    GP C
Sbjct: 1106 NGTCIDEWLTYRCACDR---GPNC 1126



 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 58/212 (27%), Positives = 78/212 (36%), Gaps = 30/212 (14%)

Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV----SACELGPC-GAARC 1562
            D C+   D C  + C  YS C+   ++ TC C     G  C     + C+  PC     C
Sbjct: 432  DYCEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLCDPNPCQNGGVC 491

Query: 1563 VPDQTPKGYSCACEPGYT-LTTSGCIESGKE-ECPGGWW-----GGSACGPCACDVTRGY 1615
                    Y+CAC  GYT    +G +   +   C  G         S    C C VT GY
Sbjct: 492  KETFDRNIYTCACPQGYTGWNCNGTLHPCETLNCTNGGTCQKQSNASDDYVCVC-VTVGY 550

Query: 1616 HPH---CNKENG--KCHCKE--NHYKPE-GTAECLPCQCY-AAGSENSSCEAAT-----G 1661
              +   C    G   C C E  N    E    EC    C   A  +N+ C+         
Sbjct: 551  CKNGATCTNTPGNYSCQCTEFTNGTNCELDINECASSPCLNGALCQNNDCDKTACFDKGY 610

Query: 1662 QCHCRPGVIGRACDACANA--YAEVTPNSGCE 1691
            +C C+ G +G  C+   +    A V PN  CE
Sbjct: 611  ECFCKSGFLGPLCEIDLDECFLAAVDPNKRCE 642



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 17/41 (41%), Positives = 26/41 (63%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C    + C+S PC NGA C+DL + + C C  G+TG +C++
Sbjct: 825  CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSE 865



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C S PC + A C+DL + + C+C   +TG+ C
Sbjct: 863  CSEDINECLSTPCQHSATCNDLVNDFSCNCTANYTGRQC 901



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S PC NGA C+DL + + C C  G+TG  C
Sbjct: 705  CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGPLC 743



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 16/44 (36%), Positives = 24/44 (54%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            C      C+SAPC++ + C D  + Y C C    TG+DC+ + G
Sbjct: 434  CEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLG 477



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 39/157 (24%), Positives = 54/157 (34%), Gaps = 18/157 (11%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEP 1577
            C   + CV   +   C C  G  G +C   +  C LG C   A C  +     Y+C C P
Sbjct: 641  CENGATCVDKVNRKECICPPGWTGDRCHVDIDECALGFCDNGATC--NNFNGTYNCTCVP 698

Query: 1578 GYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCH--CKENH 1632
            GYT    ++   E     C  G           C    GY  P C  +  +C     + +
Sbjct: 699  GYTDRNCSTDINECASNPCENGATCNDLINYFNCTCVPGYTGPLCETDVDECFLAAVDPN 758

Query: 1633 YKPEGTAECL------PCQCYAAGSENSSCEAATGQC 1663
             + E  A C+       C C   G     C    G+C
Sbjct: 759  KRCENGATCVDKVNGKECIC-PLGWTGDRCHVYIGKC 794



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 27/165 (16%)

Query: 998  DDNICVHEPCLNFEECLTVLKFGNAS------GFVNSDSV---LFRPIYP-------VTS 1041
            D N C   PC N   C  ++ + N +      GF  S+ +   L  P          V  
Sbjct: 828  DINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSEDINECLSTPCQHSATCNDLVND 887

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            F+C C   +TG  CE +  K  C        C +G +C+   + G     C   A +   
Sbjct: 888  FSCNCTANYTGRQCEYL--KTLCRPINP---CLNGGRCI---DIGFENFTCDCSAGFGGP 939

Query: 1102 VCELRAR-SFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN 1145
            +CE     S   SS+LTF G +    +   L+F T    G+L+++
Sbjct: 940  LCENSTTVSLNGSSYLTFDGSQSEFMV--ALEFRTTLPDGVLVHD 982



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354
            C   PC NG  C + +D   Y C C +G+TG +C  +  P
Sbjct: 480  CDPNPCQNGGVCKETFDRNIYTCACPQGYTGWNCNGTLHP 519



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 7/77 (9%)

Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            D C    D C L  C   + C     +  CTC  G     C   ++ C   PC   A C 
Sbjct: 665  DRCHVDIDECALGFCDNGATCNNFNGTYNCTCVPGYTDRNCSTDINECASNPCENGATC- 723

Query: 1564 PDQTPKGYSCACEPGYT 1580
             +     ++C C PGYT
Sbjct: 724  -NDLINYFNCTCVPGYT 739



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 44/174 (25%), Positives = 61/174 (35%), Gaps = 26/174 (14%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCAC 1575
            +C  + C   + C    +   CTC  G  GP C +  ++  C  A   P++        C
Sbjct: 711  ECASNPCENGATCNDLINYFNCTCVPGYTGPLCET--DVDECFLAAVDPNK-------RC 761

Query: 1576 EPGYTLTTSGCIE--SGKE-ECPGGWWGGSA---CGPCACDVTRGYHPHCNKENG--KCH 1627
            E G T     C++  +GKE  CP GW G       G CA          CN  NG   C 
Sbjct: 762  ENGAT-----CVDKVNGKECICPLGWTGDRCHVYIGKCALGFCDN-GATCNNFNGTYNCT 815

Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACAN 1679
            C   +     + +   C         ++C        C C PG  G  C    N
Sbjct: 816  CVPGYTDRNCSTDINECASNPC-ENGATCNDLINYFNCTCVPGYTGFNCSEDIN 868



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 13/34 (38%), Positives = 21/34 (61%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            +C+   C NGA C++   TY C C  G+T ++C+
Sbjct: 793  KCALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 826



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 14/40 (35%), Positives = 21/40 (52%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C+   C NGA C++   TY C C  G+T ++C+
Sbjct: 667  CHVDIDECALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 706



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 14/47 (29%), Positives = 21/47 (44%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            +  F C C  G+TG  CET + +           C +G+ CV +  G
Sbjct: 727  INYFNCTCVPGYTGPLCETDVDECFLAAVDPNKRCENGATCVDKVNG 773



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 13/36 (36%), Positives = 18/36 (50%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS 1077
            +TC CP+G+TG NC   L         +G  C+  S
Sbjct: 500  YTCACPQGYTGWNCNGTLHPCETLNCTNGGTCQKQS 535



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACE-LGPC-GAARCVPDQTPKG 1570
            +C+ + C   + C    +  +C C A   G QC    + C  + PC    RC+ D   + 
Sbjct: 869  ECLSTPCQHSATCNDLVNDFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCI-DIGFEN 927

Query: 1571 YSCACEPGY 1579
            ++C C  G+
Sbjct: 928  FTCDCSAGF 936


>SB_56285| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1127

 Score = 61.7 bits (143), Expect = 8e-09
 Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 10/112 (8%)

Query: 1652 ENSSCEAATGQ--CHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPR 1709
            E++ C    G   C CR G+IG       + ++   P      +   CP  +  G+ WPR
Sbjct: 327  EDAECINMRGSYTCMCREGLIG-------DGHSCKVPEFSTADLLTYCPAHYENGIMWPR 379

Query: 1710 TKFGVETITDCPPGSSGRATRTCDETKDVP-WQDPDMFNCTTATFYQLRKQL 1760
            T      I  CP  S+G A+R C    D P W+ PDM  C T    ++ K+L
Sbjct: 380  TAHAQTQIQRCPKDSTGVASRQCSGPADSPEWEIPDMSQCVTDAIARIHKEL 431


>SB_50568| Best HMM Match : EGF (HMM E-Value=0)
          Length = 792

 Score = 61.7 bits (143), Expect = 8e-09
 Identities = 70/264 (26%), Positives = 107/264 (40%), Gaps = 35/264 (13%)

Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDL-WDTYICDCKEGHTGKDCADSTG 1353
            D +     N T   C   ++ C    PC NG  C D+ ++ + CDC  G  G  C +ST 
Sbjct: 216  DFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCIDIGFENFTCDCSAGFGGPLCENST- 274

Query: 1354 PPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS-------IQLKSGLLHYSY 1406
                  G   L+F+      Q  ++ AL  RT   D  ++        +QLK G +  S 
Sbjct: 275  -TVSLNGSSYLTFD----GSQSEFMVALEFRTTLADGVLVHDSESKFLLQLKEGAIEIS- 328

Query: 1407 NGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIG 1466
            NG +     A LS+G W  I +    T   + +     +V +  +  K    +IG  L  
Sbjct: 329  NGASSAAIGAKLSNGNWSGI-VGLNVTQSHLQLSINTLSVSITRINRKNPKLFIGGYL-E 386

Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVR--DGCQSRADCMLSICPP 1524
             L+    L+        GCI+DV++    S++  P+  E VR   GC     C    C  
Sbjct: 387  SLEKRRNLI--------GCIRDVKV---NSVVKLPSEIELVRVSMGCPREEVCSPDPC-T 434

Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQC 1548
            +  C+  W +  C C+    GP C
Sbjct: 435  HGTCIDEWLTYRCACDR---GPNC 455



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 17/41 (41%), Positives = 26/41 (63%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C    + C+S PC NGA C+DL + + C C  G+TG +C++
Sbjct: 154  CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSE 194



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 18/43 (41%), Positives = 24/43 (55%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C    + C+S PC NGA C+DL + + C C  G+TG  C   T
Sbjct: 34   CSTDINECASNPCENGATCNDLINYFNCTCVPGYTGPLCETDT 76



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C S PC + A C+DL + + C+C   +TG+ C
Sbjct: 192  CSEDINECLSTPCQHNATCNDLVNDFSCNCTANYTGRQC 230



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 27/165 (16%)

Query: 998  DDNICVHEPCLNFEECLTVLKFGNAS------GFVNSDSV---LFRPIYP-------VTS 1041
            D N C   PC N   C  ++ + N +      GF  S+ +   L  P          V  
Sbjct: 157  DINECASNPCENGATCNDLINYFNCTCVPGYTGFNCSEDINECLSTPCQHNATCNDLVND 216

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            F+C C   +TG  CE +  K  C        C +G +C+   + G     C   A +   
Sbjct: 217  FSCNCTANYTGRQCEYL--KTLCRPINP---CLNGGRCI---DIGFENFTCDCSAGFGGP 268

Query: 1102 VCELRAR-SFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN 1145
            +CE     S   SS+LTF G +    +   L+F T    G+L+++
Sbjct: 269  LCENSTTVSLNGSSYLTFDGSQSEFMV--ALEFRTTLADGVLVHD 311



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 9/83 (10%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C L  C   + C     +  CTC  G     C   ++ C   PC   A C  +     +
Sbjct: 2    ECALGFCDNGATCNNFNGTYNCTCVPGYTDRNCSTDINECASNPCENGATC--NDLINYF 59

Query: 1572 SCACEPGYTLTTSGCIESGKEEC 1594
            +C C PGY   T    E+  +EC
Sbjct: 60   NCTCVPGY---TGPLCETDTDEC 79



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 13/34 (38%), Positives = 21/34 (61%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            +C+   C NGA C++   TY C C  G+T ++C+
Sbjct: 122  KCALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 155



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 13/33 (39%), Positives = 20/33 (60%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C+   C NGA C++   TY C C  G+T ++C+
Sbjct: 3    CALGFCDNGATCNNFNGTYNCTCVPGYTDRNCS 35



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 44/174 (25%), Positives = 60/174 (34%), Gaps = 26/174 (14%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCAC 1575
            +C  + C   + C    +   CTC  G  GP C +  +   C  A   P++        C
Sbjct: 40   ECASNPCENGATCNDLINYFNCTCVPGYTGPLCET--DTDECFLAAVDPNK-------RC 90

Query: 1576 EPGYTLTTSGCIE--SGKE-ECPGGWWGGSA---CGPCACDVTRGYHPHCNKENG--KCH 1627
            E G T     C++  +GKE  CP GW G       G CA          CN  NG   C 
Sbjct: 91   ENGAT-----CVDKVNGKECICPLGWTGDRCHVYIGKCALGFCDN-GATCNNFNGTYNCT 144

Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACAN 1679
            C   +     + +   C         ++C        C C PG  G  C    N
Sbjct: 145  CVPGYTDRNCSTDINECASNPC-ENGATCNDLINYFNCTCVPGYTGFNCSEDIN 197



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 14/47 (29%), Positives = 20/47 (42%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            +  F C C  G+TG  CET   +           C +G+ CV +  G
Sbjct: 56   INYFNCTCVPGYTGPLCETDTDECFLAAVDPNKRCENGATCVDKVNG 102



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACE-LGPC-GAARCVPDQTPKG 1570
            +C+ + C   + C    +  +C C A   G QC    + C  + PC    RC+ D   + 
Sbjct: 198  ECLSTPCQHNATCNDLVNDFSCNCTANYTGRQCEYLKTLCRPINPCLNGGRCI-DIGFEN 256

Query: 1571 YSCACEPGY 1579
            ++C C  G+
Sbjct: 257  FTCDCSAGF 265


>SB_9550| Best HMM Match : GPS (HMM E-Value=1.6e-11)
          Length = 1771

 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 18/142 (12%)

Query: 1697 CPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVP-WQDPDMFNCTTATFYQ 1755
            CP   A  + WP T    +    CP G+SG A R C +   V  W+ PD+ NC +  F  
Sbjct: 26   CPFEIARNITWPATYSEEQARQACPSGTSGTAVRMCTQKSGVAVWEPPDLENCVSVRFAL 85

Query: 1756 LRKQLHKIETGELTMNTFVGVRVAADLSTACANT------PRLYGADVVVAEGILLELMD 1809
            L+++L K         T +    AADL+ A A         ++YG DV +A   +L  + 
Sbjct: 86   LQEKLSK---------TIINANAAADLADALAQVTSPSRDEQIYGGDVKIAVS-MLRALG 135

Query: 1810 YELRQAGLNLTHSQDKDYVRNL 1831
            +       N+T  ++K+ +RN+
Sbjct: 136  HNTAIDPHNVT-EEEKEKMRNV 156



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 2238 CTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATV 2297
            C C HL++FAVL+      F        ++   T   IS+ LL  S A L          
Sbjct: 336  CHCYHLTSFAVLMQHSPDTFAVTSQHQFALGLITYIGISISLLALSLALLTFSTFTFLKS 395

Query: 2298 S-NSIHKHLIFSVFMAELLYLIAL 2320
            S N  H +L  S+ +AE+++L+ +
Sbjct: 396  SRNFAHINLTLSLILAEVIFLVGI 419


>SB_52147| Best HMM Match : EGF (HMM E-Value=0)
          Length = 364

 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 55/199 (27%), Positives = 69/199 (34%), Gaps = 18/199 (9%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA---CELGPCGAARCVPDQT 1567
            C SR D  LS    Y KCV    S  C C++G  G  C +A   C L PC    C+    
Sbjct: 19   CDSRVDWCLSSPCKYGKCVNYAGSHGCMCDSGFTGKLCENAQDPCALHPCVNGDCISSND 78

Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGYHPH-CNKE 1622
               + C C  GY  T   C E+  + C         C        CD    Y  H C   
Sbjct: 79   T--FRCVCSEGY--TGDRC-ETVVDMCISAPCHNGTCINYGSSYICDCFNSYTGHLCETL 133

Query: 1623 NGKCHCKE-NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
               CH    N            C+C  AG    SC+     C   P   G       + Y
Sbjct: 134  IDACHSNPCNDGTCIQQTGSFYCEC-LAGYTGQSCDTMIDACQSNPCNDGTCIQQTGSFY 192

Query: 1682 AE-VTPNSG--CEVVYDGC 1697
             E +T  +G  C+ + D C
Sbjct: 193  CECLTGYTGQSCDTMIDAC 211



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 13/110 (11%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQT 1567
            C +  D   S    +  C+    S  C+C+A  VG +C   V+ C   PC    C+PD +
Sbjct: 204  CDTMIDACQSNPCVHGTCIPDGSSFRCSCDAKHVGEKCNIVVNVCLSNPCAHGICIPDAS 263

Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP------CACDV 1611
               YSC CE  Y+      I       P G  G   C P      CACDV
Sbjct: 264  --SYSCMCEFMYSGKNCDIIVDPCSANPCGNHG--MCVPRDSTYYCACDV 309



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 52/218 (23%), Positives = 75/218 (34%), Gaps = 26/218 (11%)

Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPD 1565
            D C++  D  +S       C+    S  C C     G  C   + AC   PC    C+  
Sbjct: 91   DRCETVVDMCISAPCHNGTCINYGSSYICDCFNSYTGHLCETLIDACHSNPCNDGTCI-Q 149

Query: 1566 QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC----GPCACDVTRGY-HPHCN 1620
            QT   Y C C  GY  T   C ++  + C         C    G   C+   GY    C+
Sbjct: 150  QTGSFY-CECLAGY--TGQSC-DTMIDACQSNPCNDGTCIQQTGSFYCECLTGYTGQSCD 205

Query: 1621 KENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDAC 1677
                 C    C      P+G++    C C  A      C      C   P   G  C   
Sbjct: 206  TMIDACQSNPCVHGTCIPDGSS--FRCSC-DAKHVGEKCNIVVNVCLSNPCAHG-ICIPD 261

Query: 1678 ANAYA----EVTPNSGCEVVYDGCPRSFAG--GVWWPR 1709
            A++Y+     +     C+++ D C  +  G  G+  PR
Sbjct: 262  ASSYSCMCEFMYSGKNCDIIVDPCSANPCGNHGMCVPR 299



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 8/81 (9%)

Query: 1505 ENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCG-AA 1560
            ++V + C    +  LS    +  C+    S +C CE    G  C   V  C   PCG   
Sbjct: 235  KHVGEKCNIVVNVCLSNPCAHGICIPDASSYSCMCEFMYSGKNCDIIVDPCSANPCGNHG 294

Query: 1561 RCVP-DQTPKGYSCACEPGYT 1580
             CVP D T   Y CAC+ G+T
Sbjct: 295  MCVPRDST---YYCACDVGFT 312



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C SAPC+NG  C +   +YICDC   +TG  C
Sbjct: 93   CETVVDMCISAPCHNGT-CINYGSSYICDCFNSYTGHLC 130



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C   +  C+  PC NG +C    DT+ C C EG+TG  C
Sbjct: 56   CENAQDPCALHPCVNG-DCISSNDTFRCVCSEGYTGDRC 93



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C S PC +G  C     ++ C+C  G+TG+ C
Sbjct: 167  CDTMIDACQSNPCNDGT-CIQQTGSFYCECLTGYTGQSC 204



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 14/32 (43%), Positives = 15/32 (46%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CS+ PC N   C     TY C C  G TG  C
Sbjct: 285  CSANPCGNHGMCVPRDSTYYCACDVGFTGDRC 316



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            C  +   C S+PC  G +C +   ++ C C  G TGK C ++  P
Sbjct: 19   CDSRVDWCLSSPCKYG-KCVNYAGSHGCMCDSGFTGKLCENAQDP 62



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C S PC +G  C     ++ C+C  G+TG+ C
Sbjct: 130  CETLIDACHSNPCNDGT-CIQQTGSFYCECLAGYTGQSC 167



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVA---RREGGILCQGCSIDAA 1097
            +F C C EG+TG  CET++         +G+    GS  +        G LC+   IDA 
Sbjct: 79   TFRCVCSEGYTGDRCETVVDMCISAPCHNGTCINYGSSYICDCFNSYTGHLCE-TLIDAC 137

Query: 1098 YT 1099
            ++
Sbjct: 138  HS 139



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGS-ICRSGS 1077
            SF C+C  G+TG +C+T++         DG+ I ++GS
Sbjct: 153  SFYCECLAGYTGQSCDTMIDACQSNPCNDGTCIQQTGS 190


>SB_32355| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 1358

 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 1/51 (1%)

Query: 1640 ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
            + L C+C   GS N +C+   GQCHC+PGV GR CD C   +  +T  +GC
Sbjct: 1096 QALACECNPDGSVNRTCQKYAGQCHCKPGVTGRKCDQCQQGFYNLT-TTGC 1145



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 29/71 (40%), Positives = 36/71 (50%), Gaps = 9/71 (12%)

Query: 1620 NKENGKCH-CKENHYKPEGTAE-----CLPCQCYAAGSENSS--CEA-ATGQCHCRPGVI 1670
            N E   C  C+  +Y+PE  ++     C  C C  AG+ NSS  CE  A GQC C+  V 
Sbjct: 807  NTEGINCERCRPLYYRPENRSQNAVDACELCDCDTAGARNSSNICEGDAYGQCPCKQNVQ 866

Query: 1671 GRACDACANAY 1681
            G  CD C N Y
Sbjct: 867  GLRCDTCNNTY 877



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 17/96 (17%)

Query: 1603 ACGPCACDVT--RGYHPHCNKEN-GKCHCKEN------------HY--KPEGTAECLPCQ 1645
            AC  C CD    R     C  +  G+C CK+N            +Y    + T  C PC 
Sbjct: 833  ACELCDCDTAGARNSSNICEGDAYGQCPCKQNVQGLRCDTCNNTYYGLSRQDTHGCRPCL 892

Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
            C   GS +  C    GQC C P + GR CD   + Y
Sbjct: 893  CDYGGSSSPVCNKTDGQCKCLPNIDGRQCDRPLDEY 928


>SB_10244| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 205

 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 43/153 (28%), Positives = 58/153 (37%), Gaps = 23/153 (15%)

Query: 1552 CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWG--GSACGPCAC 1609
            C   P G+ R + +  P G  C C+PG      G        C  G++      C PC C
Sbjct: 62   CSCDPLGS-RTLSECEPYGGQCRCKPGVEGRDCG-------RCKPGFYNMTSEGCRPCDC 113

Query: 1610 DVTRGYHPHCNKENGKCHCKENHYKPE-----------GTAECLPCQCYAAGSENSSCEA 1658
            +V       C+   G+C CK N    +           G A C  C C   GS +  C+ 
Sbjct: 114  NVNGSSSSLCDHVTGQCSCKANVVGRDCSRCKVSSYGFGPAGCTECACNVHGSASLQCD- 172

Query: 1659 ATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691
             +G C C   VIG  C  C   Y  + P   C+
Sbjct: 173  DSGVCPCNLEVIGTKCTQCKTGYFGL-PKMACK 204



 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 12/84 (14%)

Query: 1606 PCACDVTRGYH-PHCNKENGKCHCKEN-------HYKP---EGTAE-CLPCQCYAAGSEN 1653
            PC+CD         C    G+C CK           KP     T+E C PC C   GS +
Sbjct: 61   PCSCDPLGSRTLSECEPYGGQCRCKPGVEGRDCGRCKPGFYNMTSEGCRPCDCNVNGSSS 120

Query: 1654 SSCEAATGQCHCRPGVIGRACDAC 1677
            S C+  TGQC C+  V+GR C  C
Sbjct: 121  SLCDHVTGQCSCKANVVGRDCSRC 144



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 1642 LPCQCYAAGSEN-SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
            LPC C   GS   S CE   GQC C+PGV GR C  C   +  +T + GC
Sbjct: 60   LPCSCDPLGSRTLSECEPYGGQCRCKPGVEGRDCGRCKPGFYNMT-SEGC 108


>SB_33333| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 583

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 1626 CH-CKENHYKPEGT-----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
            CH C+E  YK           C  C C+  GS    C  +TGQC C+ GV+GR+CD CA 
Sbjct: 363  CHYCREGFYKDPNKHITHIKVCRQCNCHPHGSRGRVCNQSTGQCPCKEGVVGRSCDKCAP 422

Query: 1680 AYAEVTPN 1687
             Y     N
Sbjct: 423  GYKSTKSN 430


>SB_31541| Best HMM Match : EGF (HMM E-Value=0)
          Length = 268

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 50/195 (25%), Positives = 70/195 (35%), Gaps = 16/195 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C+   +S TCTC AG  G +C   +  C  GPC       D   K ++
Sbjct: 3    ECAGNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDGVNK-FT 61

Query: 1573 CACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC--- 1626
            C+C PG+T T   +   E     C  G           C    GY    C  +   C   
Sbjct: 62   CSCIPGFTGTNCETDMDECADNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASG 121

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686
             C+      +G  +   C C   G   ++CE    +C   P   G  C    N++    P
Sbjct: 122  PCQNGATCNDGVNK-YTCSC-IPGFTGANCETDMDECAGNPCANGGTCMDGINSFTCTCP 179

Query: 1687 ----NSGCEVVYDGC 1697
                 S CE   D C
Sbjct: 180  AGYTGSKCETDIDDC 194



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 50/175 (28%), Positives = 65/175 (37%), Gaps = 39/175 (22%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C++  D C  + C     C+   +S TCTC AG  G +C   +  C  GPC       D 
Sbjct: 73   CETDMDECADNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 132

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
              K Y+C+C PG+T   + C E+  +EC G         PCA               G C
Sbjct: 133  VNK-YTCSCIPGFT--GANC-ETDMDECAGN--------PCA-------------NGGTC 167

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
                N +          C C  AG   S CE     C   P   G  C+   N Y
Sbjct: 168  MDGINSFT---------CTC-PAGYTGSKCETDIDDCASGPCQNGATCNDGVNKY 212



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 8/92 (8%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C++  D C  + C     C+   +S TCTC AG  G +C   +  C  GPC       D 
Sbjct: 149  CETDMDECAGNPCANGGTCMDGINSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 208

Query: 1567 TPKGYSCACEPGYTLT---TSGCIESGKEECP 1595
              K Y+C+C PG+T T   T+ C    K+  P
Sbjct: 209  VNK-YTCSCIPGFTGTNCETANCSGIIKDYTP 239



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362
            C      C+S PC NGA C+D  + Y C C  G TG +C     +  G P   GG   DG
Sbjct: 111  CETDIDDCASGPCQNGATCNDGVNKYTCSCIPGFTGANCETDMDECAGNPCANGGTCMDG 170

Query: 1363 MLSF 1366
            + SF
Sbjct: 171  INSF 174



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  +TC C  GFTG NCET + + +      G+ C +G  C+     GI    C+  A Y
Sbjct: 133  VNKYTCSCIPGFTGANCETDMDECA------GNPCANGGTCM----DGINSFTCTCPAGY 182

Query: 1099 TTAVCE 1104
            T + CE
Sbjct: 183  TGSKCE 188



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC NGA C+D  + Y C C  G TG +C
Sbjct: 187  CETDIDDCASGPCQNGATCNDGVNKYTCSCIPGFTGTNC 225



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T A C      C+  PC NG  C D  +++ C C  G+TG  C
Sbjct: 145  TGANCETDMDECAGNPCANGGTCMDGINSFTCTCPAGYTGSKC 187



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC NGA C+D  + + C C  G TG +C
Sbjct: 35   CETDIDDCASGPCQNGATCNDGVNKFTCSCIPGFTGTNC 73



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  FTC C  GFTG NCET + + +       + C +G  C+     GI    C+  A Y
Sbjct: 57   VNKFTCSCIPGFTGTNCETDMDECA------DNPCANGGTCM----DGINSFTCTCPAGY 106

Query: 1099 TTAVCE 1104
            T + CE
Sbjct: 107  TGSKCE 112



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 15/43 (34%), Positives = 20/43 (46%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T   C      C+  PC NG  C D  +++ C C  G+TG  C
Sbjct: 69   TGTNCETDMDECADNPCANGGTCMDGINSFTCTCPAGYTGSKC 111



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            + SFTC CP G+TG  CET +       D     C++G+ C      G+    CS    +
Sbjct: 95   INSFTCTCPAGYTGSKCETDID------DCASGPCQNGATC----NDGVNKYTCSCIPGF 144

Query: 1099 TTAVCE 1104
            T A CE
Sbjct: 145  TGANCE 150



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            + SFTC CP G+TG  CET +   +     +G+ C  G
Sbjct: 19   INSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 56



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            + SFTC CP G+TG  CET +   +     +G+ C  G
Sbjct: 171  INSFTCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 208



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+  PC NG  C D  +++ C C  G+TG  C
Sbjct: 4    CAGNPCANGGTCMDGINSFTCTCPAGYTGSKC 35



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 1039 VTSFTCQCPEGFTGVNCET 1057
            V  +TC C  GFTG NCET
Sbjct: 209  VNKYTCSCIPGFTGTNCET 227


>SB_25612| Best HMM Match : Cadherin (HMM E-Value=0.034)
          Length = 177

 Score = 59.7 bits (138), Expect = 3e-08
 Identities = 28/61 (45%), Positives = 40/61 (65%), Gaps = 2/61 (3%)

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQ 583
           ++P TG + T++ LDRET++ Y LT+T  D G P L  +    V I+V+D NDN PVF Q
Sbjct: 117 VDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQ 176

Query: 584 Q 584
           +
Sbjct: 177 E 177



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 1/62 (1%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           +D  +G L T   LDRE V  YT+ +   D   P+ +  +  AT+ + ++D+NDN P F 
Sbjct: 117 VDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLN-AAQPATVSITVLDENDNVPVFD 175

Query: 152 EK 153
           ++
Sbjct: 176 QE 177



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 2/61 (3%)

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFES 689
           +DP +GV+RT++ LDRE+V  + L     D G P  ++     V I + D ND+ PVF+ 
Sbjct: 117 VDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFDQ 176

Query: 690 D 690
           +
Sbjct: 177 E 177



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 19/39 (48%), Positives = 26/39 (66%)

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
           T+DP +G + TS +LDRET  +Y L +T  D GDP  +A
Sbjct: 116 TVDPHTGVLRTSQRLDRETVTEYTLTITVHDSGDPMLNA 154



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 4/54 (7%)

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFE 470
           G++  +Q LD +    Y LT++  DSG      +  A V I + D N+  PVF+
Sbjct: 122 GVLRTSQRLDRETVTEYTLTITVHDSGDPMLNAAQPATVSITVLDENDNVPVFD 175


>SB_31961| Best HMM Match : EGF (HMM E-Value=0)
          Length = 2813

 Score = 58.8 bits (136), Expect = 6e-08
 Identities = 61/231 (26%), Positives = 79/231 (34%), Gaps = 18/231 (7%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C++  D C  S C     C    ++ TCTC  G  G  C   +  C   PC       D 
Sbjct: 1627 CEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITCDIDIDECASSPCQNGGFCTDM 1686

Query: 1567 TPKGYSCACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKEN 1623
                ++C+C PGYT  T      E     C  G +         C    GY    C+   
Sbjct: 1687 I-NAFTCSCPPGYTGITCDINIDECASSPCQNGGFCTDMINAFTCTCLPGYTGITCDINI 1745

Query: 1624 GKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
              C    C+      +G  E   CQC +AG   + CE    +C   P      C    N 
Sbjct: 1746 DDCASRPCQNGGICKDGINE-FKCQC-SAGFTGNLCEVNIDECASAPCQHRSTCKDLIND 1803

Query: 1681 Y-AEVTPN-SG--CEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGR 1727
            Y     P  SG  CE   D C  S      +     G   +  CPPG  G+
Sbjct: 1804 YNCTCHPGYSGRNCEHEIDECISSPCRNKGYCYDAIGY-YLCICPPGFYGK 1853



 Score = 55.2 bits (127), Expect = 7e-07
 Identities = 20/39 (51%), Positives = 27/39 (69%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + ++C CKEG+TGKDC
Sbjct: 1409 CGTEIDECASEPCKNGANCTDKINGFMCTCKEGYTGKDC 1447



 Score = 54.8 bits (126), Expect = 9e-07
 Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 12/176 (6%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TCTC+ G  G  C   +  C   PC       D+   G++
Sbjct: 1035 ECASNPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRI-NGFT 1093

Query: 1573 CACEPGYTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC--- 1626
            CAC+PG+T    G    E   + C  G          AC    G+    C  E  +C   
Sbjct: 1094 CACKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDCGTEIDECASN 1153

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682
             CK N            C C   G  +  C     +C  +P   G  C    N +A
Sbjct: 1154 PCK-NGATCTDRINGFTCTC-KPGFTDKDCGTEIDECASKPCKNGATCTDRINGFA 1207



 Score = 54.8 bits (126), Expect = 9e-07
 Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 24/187 (12%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +   CTC+ G  G  C   +  C   PC       D+   G++
Sbjct: 1339 ECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRI-NGFA 1397

Query: 1573 CACEPGYTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCH-- 1627
            C C+PG+T    G    E   E C  G           C    GY    C  +  +C   
Sbjct: 1398 CTCKPGFTGKDCGTEIDECASEPCKNGANCTDKINGFMCTCKEGYTGKDCGTDIDECSSN 1457

Query: 1628 -------CKENHYK-PEGTAECLPCQCYAAGSENSSCE--AATGQCHCRPGVIGRAC--- 1674
                   C +  Y  P    E   CQ         +CE   A+ +C C+ G  GR C   
Sbjct: 1458 PCLNEGTCTDQGYTGPNCEVEVNECQSDPC-QNGGTCEDLIASYRCFCKAGYTGRHCETD 1516

Query: 1675 -DACANA 1680
             D CA++
Sbjct: 1517 IDECASS 1523



 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 43/173 (24%), Positives = 68/173 (39%), Gaps = 26/173 (15%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TCTC+ G     C   +  C   PC       D+   G++
Sbjct: 1149 ECASNPCKNGATCTDRINGFTCTCKPGFTDKDCGTEIDECASKPCKNGATCTDRI-NGFA 1207

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG-KCHCKEN 1631
            CAC+PG+T         GK +C      G+    CA +  +      ++ NG  C CK  
Sbjct: 1208 CACKPGFT---------GK-DC------GTEIDECASNPCKNGATCTDRINGFTCTCKPG 1251

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRAC----DACAN 1679
                +   E   C      +  +  +   G +C C+PG  G+ C    D CA+
Sbjct: 1252 FTGKDCGTEIDECASKPCKNGATCTDRINGFRCTCKPGFTGKDCGTEIDECAS 1304



 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 18/39 (46%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S+PC NG  C+DL D + C C  G+TGK+C
Sbjct: 1513 CETDIDECASSPCANGGTCTDLVDAHKCQCSTGYTGKNC 1551



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 20/43 (46%), Positives = 26/43 (60%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T + C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1025 TGSDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGKDC 1067



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 43/173 (24%), Positives = 66/173 (38%), Gaps = 26/173 (15%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TCTC+ G  G  C   +  C   PC       D+   G+ 
Sbjct: 1225 ECASNPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRI-NGFR 1283

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG-KCHCKEN 1631
            C C+PG+T         GK +C      G+    CA +  +      ++ NG  C CK  
Sbjct: 1284 CTCKPGFT---------GK-DC------GTEIDECASNPCKNGATCTDRINGFTCTCKPG 1327

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRAC----DACAN 1679
                +   E   C      +  +  +   G  C C+PG  G+ C    D CA+
Sbjct: 1328 FTGSDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECAS 1380



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 20/43 (46%), Positives = 26/43 (60%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T + C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1329 TGSDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDC 1371



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 43/181 (23%), Positives = 57/181 (31%), Gaps = 12/181 (6%)

Query: 1510 GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPD 1565
            GC    +C  + C     C    +S  CTC +G  G +C      C   PC     C  D
Sbjct: 877  GCVEIDECSSNPCQNGGTCTDQLNSYLCTCPSGYTGTKCEIVPDQCASAPCINGGTCKSD 936

Query: 1566 QTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKE 1622
            +   GY C C+ G+T     +   E     C  G           C    G+    C  E
Sbjct: 937  R--YGYHCHCKVGFTGKNCETNIDECNSSPCKNGGSCTDRISGFTCTCKHGFTGKDCGTE 994

Query: 1623 NGKCHCK--ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
              +C  K  +N            C C   G   S C     +C   P   G  C    N 
Sbjct: 995  IDECASKPCKNGATCTDRINGFTCTC-KPGFTGSDCGTEIDECASNPCKNGATCTDRING 1053

Query: 1681 Y 1681
            +
Sbjct: 1054 F 1054



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 18/39 (46%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S+PC NG  C+D    + C CK G TGKDC
Sbjct: 953  CETNIDECNSSPCKNGGSCTDRISGFTCTCKHGFTGKDC 991



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1067 CGTEIDECASKPCKNGATCTDRINGFTCACKPGFTGKDC 1105



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1105 CGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDC 1143



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1181 CGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDC 1219



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1219 CGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGKDC 1257



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1371 CGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDC 1409



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TGKDC
Sbjct: 1257 CGTEIDECASKPCKNGATCTDRINGFRCTCKPGFTGKDC 1295



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 19/40 (47%), Positives = 24/40 (60%), Gaps = 1/40 (2%)

Query: 1309 GCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            GC E    CSS PC NG  C+D  ++Y+C C  G+TG  C
Sbjct: 877  GCVEI-DECSSNPCQNGGTCTDQLNSYLCTCPSGYTGTKC 915



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TG DC
Sbjct: 991  CGTEIDECASKPCKNGATCTDRINGFTCTCKPGFTGSDC 1029



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 1/47 (2%)

Query: 1303 DNG-TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            D G T   C  + + C S PC NG  C DL  +Y C CK G+TG+ C
Sbjct: 1467 DQGYTGPNCEVEVNECQSDPCQNGGTCEDLIASYRCFCKAGYTGRHC 1513



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G TG DC
Sbjct: 1295 CGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGSDC 1333



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC NGA C+D  + + C CK G T KDC
Sbjct: 1143 CGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTDKDC 1181



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 3/55 (5%)

Query: 1297 LNSYVAD--NG-TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            LNSY+    +G T   C     +C+SAPC NG  C      Y C CK G TGK+C
Sbjct: 899  LNSYLCTCPSGYTGTKCEIVPDQCASAPCINGGTCKSDRYGYHCHCKVGFTGKNC 953



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S+PC NG  C+D+ + + C C  G+TG  C
Sbjct: 1627 CEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITC 1665



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S+PC NG  C+D+ + + C C  G+TG  C
Sbjct: 1665 CDIDIDECASSPCQNGGFCTDMINAFTCSCPPGYTGITC 1703



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S+PC NG  C+D+ + + C C  G+TG  C
Sbjct: 1703 CDINIDECASSPCQNGGFCTDMINAFTCTCLPGYTGITC 1741



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+SAPC + + C DL + Y C C  G++G++C
Sbjct: 1779 CEVNIDECASAPCQHRSTCKDLINDYNCTCHPGYSGRNC 1817



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 66/279 (23%), Positives = 92/279 (32%), Gaps = 32/279 (11%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C+   D C    C   + CV       C C  G  G QC   +  C   PC       D 
Sbjct: 1551 CEVNIDECATKPCLNGATCVDQIAVYKCLCAPGYKGLQCQIDIDECASNPCQNNGYCEDL 1610

Query: 1567 TPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKEN 1623
               GY C C PG++     +   E     C  G           C    GY    C+ + 
Sbjct: 1611 I-NGYYCFCTPGFSGIHCEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITCDIDI 1669

Query: 1624 GKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
             +C    C+   +  +       C C   G    +C+    +C   P   G  C    NA
Sbjct: 1670 DECASSPCQNGGFCTD-MINAFTCSC-PPGYTGITCDINIDECASSPCQNGGFCTDMINA 1727

Query: 1681 Y-AEVTPN-SG--CEVVYDGCPRSFA--GGVWWPRTKFGV-ETITDCPPGSSGRATR-TC 1732
            +     P  +G  C++  D C       GG+     K G+ E    C  G +G       
Sbjct: 1728 FTCTCLPGYTGITCDINIDDCASRPCQNGGI----CKDGINEFKCQCSAGFTGNLCEVNI 1783

Query: 1733 DETKDVPWQD----PDM---FNCTTATFYQLRKQLHKIE 1764
            DE    P Q      D+   +NCT    Y  R   H+I+
Sbjct: 1784 DECASAPCQHRSTCKDLINDYNCTCHPGYSGRNCEHEID 1822



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 44/174 (25%), Positives = 61/174 (35%), Gaps = 32/174 (18%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  S C     C    ++ TCTC  G  G  C   +  C   PC       D   + + 
Sbjct: 1709 ECASSPCQNGGFCTDMINAFTCTCLPGYTGITCDINIDDCASRPCQNGGICKDGINE-FK 1767

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPC----AC-DVTRGYHPHCNKENGKCH 1627
            C C  G+T       E   +EC        A  PC     C D+   Y+  C+      +
Sbjct: 1768 CQCSAGFT---GNLCEVNIDEC--------ASAPCQHRSTCKDLINDYNCTCHPGYSGRN 1816

Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIGRACDACAN 1679
            C+          EC+   C   G     C  A G   C C PG  G+ C+  A+
Sbjct: 1817 CEHE------IDECISSPCRNKGY----CYDAIGYYLCICPPGFYGKHCENLAS 1860



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 21/66 (31%), Positives = 25/66 (37%), Gaps = 5/66 (7%)

Query: 1283 GCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEG 1342
            G  +D    HK      Y   N     C      C++ PC NGA C D    Y C C  G
Sbjct: 1529 GTCTDLVDAHKCQCSTGYTGKN-----CEVNIDECATKPCLNGATCVDQIAVYKCLCAPG 1583

Query: 1343 HTGKDC 1348
            + G  C
Sbjct: 1584 YKGLQC 1589



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD--STG 1353
            C  +   C S+PC N   C D    Y+C C  G  GK C +  STG
Sbjct: 1817 CEHEIDECISSPCRNKGYCYDAIGYYLCICPPGFYGKHCENLASTG 1862



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 15/39 (38%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC N   C DL + Y C C  G +G  C
Sbjct: 1589 CQIDIDECASNPCQNNGYCEDLINGYYCFCTPGFSGIHC 1627



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 8/74 (10%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG-----SQCVARREGGILCQGCS 1093
            + +FTC C  G+TG+ C+  +   +     +G IC+ G      QC A   G  LC+  +
Sbjct: 1725 INAFTCTCLPGYTGITCDINIDDCASRPCQNGGICKDGINEFKCQCSAGFTGN-LCE-VN 1782

Query: 1094 IDAAYTTAVCELRA 1107
            ID    +A C+ R+
Sbjct: 1783 IDEC-ASAPCQHRS 1795



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 14/32 (43%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S PC NG  C D  + + C C  G TG  C
Sbjct: 1748 CASRPCQNGGICKDGINEFKCQCSAGFTGNLC 1779



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            + +FTC CP G+TG+ C+  + + +       S C++G  C       I    CS    Y
Sbjct: 1649 INAFTCTCPPGYTGITCDIDIDECA------SSPCQNGGFCTDM----INAFTCSCPPGY 1698

Query: 1099 TTAVCEL 1105
            T   C++
Sbjct: 1699 TGITCDI 1705



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 11/35 (31%), Positives = 20/35 (57%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073
            + +FTC CP G+TG+ C+  + + +     +G  C
Sbjct: 1687 INAFTCSCPPGYTGITCDINIDECASSPCQNGGFC 1721



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 8/90 (8%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-----REGGILCQ 1090
            +  FTC C  GFTG +C T + + + +   +G+ C    +G +C  +     ++ G    
Sbjct: 1241 INGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFRCTCKPGFTGKDCGTEID 1300

Query: 1091 GCSIDAAYTTAVCELRARSFPVSSFLTFPG 1120
             C+ +     A C  R   F  +    F G
Sbjct: 1301 ECASNPCKNGATCTDRINGFTCTCKPGFTG 1330



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 10/75 (13%)

Query: 1011 EECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDG 1070
            + C T +   N+S   N  S   R    ++ FTC C  GFTG +C T + + + +     
Sbjct: 951  KNCETNIDECNSSPCKNGGSCTDR----ISGFTCTCKHGFTGKDCGTEIDECASKP---- 1002

Query: 1071 SICRSGSQCVARREG 1085
              C++G+ C  R  G
Sbjct: 1003 --CKNGATCTDRING 1015



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 12/37 (32%), Positives = 20/37 (54%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS 1075
            + S+ C CP G+TG  CE +  + +     +G  C+S
Sbjct: 899  LNSYLCTCPSGYTGTKCEIVPDQCASAPCINGGTCKS 935



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 6/44 (13%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            + C C  GFTG NCET + +       + S C++G  C  R  G
Sbjct: 940  YHCHCKVGFTGKNCETNIDEC------NSSPCKNGGSCTDRISG 977



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 8/80 (10%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-----REGGILCQ 1090
            +  FTC C  GFTG +C T + + + +   +G+ C    +G  C  +     ++ G    
Sbjct: 1089 INGFTCACKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFACACKPGFTGKDCGTEID 1148

Query: 1091 GCSIDAAYTTAVCELRARSF 1110
             C+ +     A C  R   F
Sbjct: 1149 ECASNPCKNGATCTDRINGF 1168



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 8/90 (8%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-----REGGILCQ 1090
            +  FTC C  GFTG +C T + + +     +G+ C    +G  C  +     ++ G    
Sbjct: 1317 INGFTCTCKPGFTGSDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEID 1376

Query: 1091 GCSIDAAYTTAVCELRARSFPVSSFLTFPG 1120
             C+ +     A C  R   F  +    F G
Sbjct: 1377 ECASNPCKNGATCTDRINGFACTCKPGFTG 1406



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 6/47 (12%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            +  FTC C  GFTG +C T + + +       + C++G+ C  R  G
Sbjct: 1013 INGFTCTCKPGFTGSDCGTEIDECA------SNPCKNGATCTDRING 1053



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 6/47 (12%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            +  FTC C  GFTG +C T + + + +       C++G+ C  R  G
Sbjct: 1051 INGFTCTCKPGFTGKDCGTEIDECASKP------CKNGATCTDRING 1091



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 10/65 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  F C C  GFTG +C T + + + E       C++G+ C  +  G +    C+    Y
Sbjct: 1393 INGFACTCKPGFTGKDCGTEIDECASEP------CKNGANCTDKINGFM----CTCKEGY 1442

Query: 1099 TTAVC 1103
            T   C
Sbjct: 1443 TGKDC 1447


>SB_32940| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1025

 Score = 58.8 bits (136), Expect = 6e-08
 Identities = 45/174 (25%), Positives = 61/174 (35%), Gaps = 12/174 (6%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSC 1573
            C  S C   S CV   D+  C C  G  G  C   ++ C   PC    C+      GY C
Sbjct: 441  CSSSPCENNSTCVNKLDTFKCFCTPGYTGSHCEVNINECASSPCQYGTCI--DLIDGYRC 498

Query: 1574 ACEPGYTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCHCK- 1629
             C+PG+  T  G    E     C  G +         CD   GY   HC ++   C  + 
Sbjct: 499  YCKPGFGGTNCGLNLNECLSNPCYNGGFCVDEENNYRCDCGHGYRGRHCEEDVDLCKEEG 558

Query: 1630 --ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
               N    +     + CQC   G   ++C      C   P + G  C    N +
Sbjct: 559  WCVNAISCKDNGNSVDCQC-KPGFTGANCAVDIHDCVNNPCMNGGTCKDKVNDF 611



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 18/41 (43%), Positives = 23/41 (56%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            AG       C+S+PC NG  C D  D+Y C CK+G  G +C
Sbjct: 118  AGSDIDEDECASSPCRNGGLCIDQVDSYKCSCKQGTFGLNC 158



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 17/41 (41%), Positives = 22/41 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C    + C S PCYNG  C D  + Y CDC  G+ G+ C +
Sbjct: 509  CGLNLNECLSNPCYNGGFCVDEENNYRCDCGHGYRGRHCEE 549



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 16/39 (41%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  + + CSS+PC N + C +  DT+ C C  G+TG  C
Sbjct: 434  CDTELNACSSSPCENNSTCVNKLDTFKCFCTPGYTGSHC 472



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 18/43 (41%), Positives = 21/43 (48%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T A C      C + PC NG  C D  + + C CK G TGK C
Sbjct: 582  TGANCAVDIHDCVNNPCMNGGTCKDKVNDFECFCKPGFTGKTC 624



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 45/168 (26%), Positives = 59/168 (35%), Gaps = 17/168 (10%)

Query: 1522 CPPYSKCVTSWDSST--CTCEAGRVGPQCVSA--CELGPC--GAARCVPDQTPKG-YSCA 1574
            C  + +CVT++  S+  C C  G  G  C     C   PC  GA     +  P+  Y+C 
Sbjct: 327  CSNHGQCVTNFSMSSYQCKCCGGFRGEFCEKEDHCFSKPCKNGATCKNKEGDPRHFYTCT 386

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA----CDVTRGY-HPHCNKENGKCHCK 1629
            C PGY       +       P      +AC P      C   RGY    C+ E   C   
Sbjct: 387  CAPGYEGRDCSRVIDMCVSNPCKL--NAACTPLVNDFHCSCPRGYTGKTCDTELNACSSS 444

Query: 1630 --ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
              EN+       +   C C   G   S CE    +C   P   G   D
Sbjct: 445  PCENNSTCVNKLDTFKCFC-TPGYTGSHCEVNINECASSPCQYGTCID 491



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 4/42 (9%)

Query: 1312 EKRSRCSSAPCYNGAEC----SDLWDTYICDCKEGHTGKDCA 1349
            EK   C S PC NGA C     D    Y C C  G+ G+DC+
Sbjct: 356  EKEDHCFSKPCKNGATCKNKEGDPRHFYTCTCAPGYEGRDCS 397



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S+PC  G  C DL D Y C CK G  G +C
Sbjct: 472  CEVNINECASSPCQYGT-CIDLIDGYRCYCKPGFGGTNC 509



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C S PC   A C+ L + + C C  G+TGK C
Sbjct: 396  CSRVIDMCVSNPCKLNAACTPLVNDFHCSCPRGYTGKTC 434



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  F C CP G+TG  C+T L   S       S C + S CV + +       C     Y
Sbjct: 418  VNDFHCSCPRGYTGKTCDTELNACS------SSPCENNSTCVNKLD----TFKCFCTPGY 467

Query: 1099 TTAVCEL 1105
            T + CE+
Sbjct: 468  TGSHCEV 474



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C   PC NG  CS     ++CDC +G+ G  C
Sbjct: 53   CLPNPCTNGGLCSVNGTNFLCDCPQGYRGDRC 84



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 4/73 (5%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPG 1578
            C     C  + +S  C C+ G  G  C   +  C   PC       D+    + C C+PG
Sbjct: 560  CVNAISCKDNGNSVDCQCKPGFTGANCAVDIHDCVNNPCMNGGTCKDKV-NDFECFCKPG 618

Query: 1579 YTLTTSGCIESGK 1591
            +T  T   ++  +
Sbjct: 619  FTGKTCELLDGSR 631



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 1/41 (2%)

Query: 1310 CPEKRSRCSSAP-CYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C E    C     C N   C D  ++  C CK G TG +CA
Sbjct: 547  CEEDVDLCKEEGWCVNAISCKDNGNSVDCQCKPGFTGANCA 587


>SB_58558| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1101

 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 44/167 (26%), Positives = 54/167 (32%), Gaps = 10/167 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQTPKGYS 1572
            DC  + C   + C+   +S TC C  G  G QC      C+  PC       DQ   GY 
Sbjct: 582  DCASTPCMNGATCLDGVNSYTCICVTGWTGDQCTINPDNCQSAPCQNNGTCTDQV-NGYL 640

Query: 1573 CACEPGY--TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKENGKCHCK 1629
            C C PG+          E     C  G       G   C    GY   HC  +  +C   
Sbjct: 641  CDCTPGWYGKACEHDVDECSSNPCVNGGTCNDEAGGYTCTCAAGYTGLHCETDIDECRTN 700

Query: 1630 E--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
               N            C C A G     CE     C  +P + G  C
Sbjct: 701  PCLNGATCTDKVNSYTCTC-APGYAGVHCEKDEDDCASKPCLNGGTC 746



 Score = 57.6 bits (133), Expect = 1e-07
 Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 21/185 (11%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C+  AD C    C     C    D+  CTC  G  G +C   ++ C+  PC       D+
Sbjct: 500  CEINADDCQSMPCLNGGSCKDKVDAYECTCPLGYTGLRCETDINDCQPNPCLNGGSCTDR 559

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPG-GWWGGSAC------GPCACDVTRGYHPHC 1619
               GY+CAC PGY  T + C E   ++C       G+ C        C C VT      C
Sbjct: 560  V-NGYTCACAPGY--TGNNC-EKDIDDCASTPCMNGATCLDGVNSYTCIC-VTGWTGDQC 614

Query: 1620 NKENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676
                  C    C+ N    +     L C C   G    +CE    +C   P V G  C+ 
Sbjct: 615  TINPDNCQSAPCQNNGTCTDQVNGYL-CDC-TPGWYGKACEHDVDECSSNPCVNGGTCND 672

Query: 1677 CANAY 1681
             A  Y
Sbjct: 673  EAGGY 677



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 59/231 (25%), Positives = 80/231 (34%), Gaps = 36/231 (15%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C    C   + C   +++ TCTC AG  G  C   +  C    C     CV      GY
Sbjct: 239  ECAPQPCKNGATCNNLFNNYTCTCAAGYTGINCTENIDDCNGVVCQNGGNCV--DGVNGY 296

Query: 1572 SCACEPGYTLTTSGCIESGKEECP-GGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
             C+C PGY  T S C E+   EC       G  C     D+  G+   C        C+ 
Sbjct: 297  KCSCAPGY--TGSNC-ETDINECAVNSCQNGGNC----TDLVNGFSCTCAPGYTGHRCET 349

Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN-AYAEVTPNSG 1689
            +        +C    C   G+          +C C  G +G  C    N    +   N G
Sbjct: 350  D------IDDCASAPCRNGGTCTDQVNGY--RCQCALGFVGSYCQINVNDCIPDPCQNGG 401

Query: 1690 ---CEVVYDG---CPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDE 1734
               C++V D    CP  + G       K   E I DC P   G      D+
Sbjct: 402  FCCCDLVNDWICLCPGGWGG-------KNCTENINDCDPNPCGNGGTCTDQ 445



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 17/42 (40%), Positives = 26/42 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            C E    C+  PC NGA C++L++ Y C C  G+TG +C ++
Sbjct: 233  CTEDVDECAPQPCKNGATCNNLFNNYTCTCAAGYTGINCTEN 274



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 57/239 (23%), Positives = 82/239 (34%), Gaps = 25/239 (10%)

Query: 1500 RPTVRENVRDGC--QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL 1554
            R  +R N    C  Q   DC  S C     C    ++  C C  G VG  C   ++ C  
Sbjct: 144  RYEIRRNSEYYCYLQGIDDCAPSPCRNNGTCTDMHNAYRCQCTQGFVGKNCQININDCIP 203

Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTR 1613
             PC     C  D     + C C  G+  T   C E   E  P     G+ C     ++  
Sbjct: 204  DPCQNGGWCCCDLV-NDWICQCPKGW--TGKNCTEDVDECAPQPCKNGATCN----NLFN 256

Query: 1614 GYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGR 1672
             Y   C       +C EN        +C    C   G   +  +   G +C C PG  G 
Sbjct: 257  NYTCTCAAGYTGINCTEN------IDDCNGVVCQNGG---NCVDGVNGYKCSCAPGYTGS 307

Query: 1673 ACDACANAYAEVTPNSG--CEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRAT 1729
             C+   N  A  +  +G  C  + +G   + A G    R +  ++     P  + G  T
Sbjct: 308  NCETDINECAVNSCQNGGNCTDLVNGFSCTCAPGYTGHRCETDIDDCASAPCRNGGTCT 366



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 42/164 (25%), Positives = 58/164 (35%), Gaps = 20/164 (12%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  + C     C    ++  CTC  G  G +C   ++ C   PC       DQ   GY+
Sbjct: 430  DCDPNPCGNGGTCTDQLNAYLCTCPPGYTGSKCEIDINECASFPCQNGGSCTDQV-NGYT 488

Query: 1573 CACEPGYTLTTSGCIESGKEECPG-GWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            C+C  GY  +   C E   ++C       G +C     D    Y   C        C+ +
Sbjct: 489  CSCAAGY--SGVNC-EINADDCQSMPCLNGGSCK----DKVDAYECTCPLGYTGLRCETD 541

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
                    +C P  C   GS        T  C C PG  G  C+
Sbjct: 542  ------INDCQPNPCLNGGSCTDRVNGYT--CACAPGYTGNNCE 577



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 45/176 (25%), Positives = 57/176 (32%), Gaps = 14/176 (7%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  + C     C    +  TC C  G  G  C   +  C   PC   A C+       Y
Sbjct: 544  DCQPNPCLNGGSCTDRVNGYTCACAPGYTGNNCEKDIDDCASTPCMNGATCLDGVN--SY 601

Query: 1572 SCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
            +C C  G+T    T          C              CD T G++     E+    C 
Sbjct: 602  TCICVTGWTGDQCTINPDNCQSAPCQNNGTCTDQVNGYLCDCTPGWYGKAC-EHDVDECS 660

Query: 1630 ENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
             N     GT    A    C C AAG     CE    +C   P + G  C    N+Y
Sbjct: 661  SNPCVNGGTCNDEAGGYTCTC-AAGYTGLHCETDIDECRTNPCLNGATCTDKVNSY 715



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C   PC NG  C+D  + Y+C C  G+TG  C
Sbjct: 424  CTENINDCDPNPCGNGGTCTDQLNAYLCTCPPGYTGSKC 462



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/39 (43%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C SAPC N   C+D  + Y+CDC  G  GK C
Sbjct: 614  CTINPDNCQSAPCQNNGTCTDQVNGYLCDCTPGWYGKAC 652



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/39 (43%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C S PC NG  C D  D Y C C  G+TG  C
Sbjct: 500  CEINADDCQSMPCLNGGSCKDKVDAYECTCPLGYTGLRC 538



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/39 (43%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      CSS PC NG  C+D    Y C C  G+TG  C
Sbjct: 652  CEHDVDECSSNPCVNGGTCNDEAGGYTCTCAAGYTGLHC 690



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/41 (41%), Positives = 21/41 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C +    C+S PC NG  C+DL   + C C  G  GK C D
Sbjct: 728  CEKDEDDCASKPCLNGGTCTDLLADFECACVLGFIGKTCND 768



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S PC NG  C+D  + Y C C  G++G +C
Sbjct: 462  CEIDINECASFPCQNGGSCTDQVNGYTCSCAAGYSGVNC 500



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    C+S PC NGA C D  ++Y C C  G TG  C
Sbjct: 576  CEKDIDDCASTPCMNGATCLDGVNSYTCICVTGWTGDQC 614



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+ +PC N   C+D+ + Y C C +G  GK+C
Sbjct: 163  CAPSPCRNNGTCTDMHNAYRCQCTQGFVGKNC 194



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C   PC NG  C+D  + Y C C  G+TG +C
Sbjct: 538  CETDINDCQPNPCLNGGSCTDRVNGYTCACAPGYTGNNC 576



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C + PC NGA C+D  ++Y C C  G+ G  C
Sbjct: 690  CETDIDECRTNPCLNGATCTDKVNSYTCTCAPGYAGVHC 728



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            ++TC C  G+TG+NC   +       D +G +C++G  CV     G+    CS    YT 
Sbjct: 257  NYTCTCAAGYTGINCTENID------DCNGVVCQNGGNCV----DGVNGYKCSCAPGYTG 306

Query: 1101 AVCELRARSFPVSS 1114
            + CE       V+S
Sbjct: 307  SNCETDINECAVNS 320



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            T + C    + C+   C NG  C+DL + + C C  G+TG  C     D    P R GG
Sbjct: 305  TGSNCETDINECAVNSCQNGGNCTDLVNGFSCTCAPGYTGHRCETDIDDCASAPCRNGG 363



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E    C+   C NG  C D  + Y C C  G+TG +C
Sbjct: 271  CTENIDDCNGVVCQNGGNCVDGVNGYKCSCAPGYTGSNC 309



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCAD 1350
            C    + C   PC NG  C  DL + +IC C +G TGK+C +
Sbjct: 194  CQININDCIPDPCQNGGWCCCDLVNDWICQCPKGWTGKNCTE 235



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 16/39 (41%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+SAPC NG  C+D  + Y C C  G  G  C
Sbjct: 347  CETDIDDCASAPCRNGGTCTDQVNGYRCQCALGFVGSYC 385



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  + C C  G+TG NCET + +  C V+     C++G  C     G      C+    Y
Sbjct: 293  VNGYKCSCAPGYTGSNCETDINE--CAVNS----CQNGGNCTDLVNG----FSCTCAPGY 342

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 343  TGHRCE 348



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 10/69 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            + ++ C CP G+TG  CE  + + +         C++G  C  +  G      CS  A Y
Sbjct: 446  LNAYLCTCPPGYTGSKCEIDINECA------SFPCQNGGSCTDQVNG----YTCSCAAGY 495

Query: 1099 TTAVCELRA 1107
            +   CE+ A
Sbjct: 496  SGVNCEINA 504



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V ++ C CP G+TG+ CET +       D   + C +G  C  R  G      C+    Y
Sbjct: 522  VDAYECTCPLGYTGLRCETDIN------DCQPNPCLNGGSCTDRVNG----YTCACAPGY 571

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 572  TGNNCE 577



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 1/43 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCADS 1351
            C    + C   PC NG  C  DL + +IC C  G  GK+C ++
Sbjct: 385  CQINVNDCIPDPCQNGGFCCCDLVNDWICLCPGGWGGKNCTEN 427



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 12/37 (32%), Positives = 22/37 (59%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS 1075
            V  + CQCP+G+TG NC   + + + +   +G+ C +
Sbjct: 217  VNDWICQCPKGWTGKNCTEDVDECAPQPCKNGATCNN 253



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  F+C C  G+TG  CET +       D   + CR+G  C   +  G  CQ C++   +
Sbjct: 331  VNGFSCTCAPGYTGHRCETDID------DCASAPCRNGGTC-TDQVNGYRCQ-CAL--GF 380

Query: 1099 TTAVCEL 1105
              + C++
Sbjct: 381  VGSYCQI 387



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  +TC C  G++GVNCE  +    C+       C +G  C    +  +    C+    Y
Sbjct: 484  VNGYTCSCAAGYSGVNCE--INADDCQ----SMPCLNGGSC----KDKVDAYECTCPLGY 533

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 534  TGLRCE 539



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            V  +TC C  G+TG NCE  +   +     +G+ C  G
Sbjct: 560  VNGYTCACAPGYTGNNCEKDIDDCASTPCMNGATCLDG 597


>SB_20112| Best HMM Match : EGF (HMM E-Value=0)
          Length = 2112

 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 53/205 (25%), Positives = 74/205 (36%), Gaps = 28/205 (13%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C++  D C    C   + C  +  + TCTC AG  G  C   ++ C   PC    C+   
Sbjct: 795  CRTNIDECAKGPCKYGATCHDAVANYTCTCTAGFTGKNCDININECASNPCQRGSCL--D 852

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625
               GY C+C  GY      C E   ++C     + G +C     D    +   C      
Sbjct: 853  LVNGYLCSCPKGY--IGKHC-EVNADDCFVNACFNGGSC----VDGIAEFKCTCPLGFSG 905

Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685
              C+ +        EC    C A G+E          C C+ G +GR CD   N      
Sbjct: 906  SRCEVD------VDECASSPCSALGTEKCINNIGAYHCQCKQGFLGRHCDLNINECLSYP 959

Query: 1686 PNSGCEVVYDG-------CPRSFAG 1703
              +G E   DG       CP  F+G
Sbjct: 960  CRNGGE-CKDGAGEYTCLCPHGFSG 983



 Score = 57.6 bits (133), Expect = 1e-07
 Identities = 51/181 (28%), Positives = 68/181 (37%), Gaps = 24/181 (13%)

Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVP 1564
            D CQ   D C  S C     C+   ++ TC C  G  GP+C   ++ C   PC       
Sbjct: 636  DRCQINVDDCQSSPCVHGGSCIDGINTYTCQCPKGFTGPRCEIHINECSSDPCQHGGTCS 695

Query: 1565 DQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHC--NK 1621
            D+    YSC C PGY  T S C +   + C       G+ C     D++  +H  C    
Sbjct: 696  DRI-GSYSCYCRPGY--TGSNC-QHPLDRCANDPCRNGATCRRTGEDLS-DFHCECPLGY 750

Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC----DAC 1677
            +   C  KE      GT       C+ +    S        C C+PG  G  C    D C
Sbjct: 751  KGTICDVKEVSCAVAGTICANGGTCFDSNGVQS--------CTCKPGFTGSYCRTNIDEC 802

Query: 1678 A 1678
            A
Sbjct: 803  A 803



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 45/168 (26%), Positives = 56/168 (33%), Gaps = 20/168 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  S C     C        C C  G  G  C   + +C    C   A CV   TP  Y
Sbjct: 530  ECASSPCRNGGTCEDGVAQYYCRCRDGYTGKNCEVRIDSCIDHTCQNGASCV-SSTPYAY 588

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            SC C+PGY   T    E+  +EC        AC     D   G+   C+       C+ N
Sbjct: 589  SCQCKPGY---TGQYCETDVDECAARPCVNGAC----VDGVNGFICRCDPGFTGDRCQIN 641

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
                    +C    C   GS        T  C C  G  G  C+   N
Sbjct: 642  ------VDDCQSSPCVHGGSCIDGINTYT--CQCPKGFTGPRCEIHIN 681



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 17/39 (43%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S+PC NG  C D    Y C C++G+TGK+C
Sbjct: 524  CGVPVNECASSPCRNGGTCEDGVAQYYCRCRDGYTGKNC 562



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 18/41 (43%), Positives = 22/41 (53%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A C E  + C S PC NG  C D+ + Y CDC     GK+C
Sbjct: 1060 ANCEESINECLSQPCKNGGSCRDIVNGYKCDCPSKMIGKNC 1100



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 46/197 (23%), Positives = 68/197 (34%), Gaps = 20/197 (10%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  + C     C+   ++ +C C  G  G  C   V+ C   PC       D   + Y 
Sbjct: 492  DCPANACQNGGVCIDGMNTYSCKCHPGFTGFSCGVPVNECASSPCRNGGTCEDGVAQ-YY 550

Query: 1573 CACEPGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKC 1626
            C C  GYT     +    CI+   +   G     S     +C    GY   +C  +  +C
Sbjct: 551  CRCRDGYTGKNCEVRIDSCIDHTCQN--GASCVSSTPYAYSCQCKPGYTGQYCETDVDEC 608

Query: 1627 HCKE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV 1684
              +   N    +G    + C+C   G     C+     C   P V G +C    N Y   
Sbjct: 609  AARPCVNGACVDGVNGFI-CRC-DPGFTGDRCQINVDDCQSSPCVHGGSCIDGINTYTCQ 666

Query: 1685 TPNS----GCEVVYDGC 1697
             P       CE+  + C
Sbjct: 667  CPKGFTGPRCEIHINEC 683



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + CSS PC +G  CSD   +Y C C+ G+TG +C
Sbjct: 676  CEIHINECSSDPCQHGGTCSDRIGSYSCYCRPGYTGSNC 714



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/42 (40%), Positives = 22/42 (52%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            C   +  C SAPC NG  C D + +Y C C  G  G +C +S
Sbjct: 1024 CEWNKDECLSAPCRNGGTCIDGYGSYSCKCPLGFAGANCEES 1065



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 56/230 (24%), Positives = 81/230 (35%), Gaps = 30/230 (13%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C  +  C+   +   C C  G  G  C   ++ C+  PC    +C        Y
Sbjct: 303  ECESNPCV-HGLCLDYQNKFECACSKGYTGRLCDVEINECDSNPCLNGGQC--HDGLGNY 359

Query: 1572 SCACEPGYT--LTTSGCIESGKEECP--GGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627
            SC C+ GY   +  +   +     C   G    G A   C C +  G+     + N    
Sbjct: 360  SCTCQVGYVGEICQTNYDDCASNPCQNDGTCQDGIAQYTCLCPL--GFTGKSCETNTN-E 416

Query: 1628 CKENHYKPEGTA----ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAE 1683
            C  N     GT         CQC   G   + CE    +C   P   G  C    N Y  
Sbjct: 417  CAGNPCMNMGTCIDGINSFRCQC-PLGFTGNRCETEIDECESSPCQNGGTCKDKINGYVC 475

Query: 1684 VTP----NSGCEVVYDGCPRSFA--GGVWWPRTKFGVETIT-DCPPGSSG 1726
            + P     + CE   + CP +    GGV       G+ T +  C PG +G
Sbjct: 476  ICPPGASGTHCENDPNDCPANACQNGGVCID----GMNTYSCKCHPGFTG 521



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 50/193 (25%), Positives = 64/193 (33%), Gaps = 23/193 (11%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPCGA-ARCVPDQTPKGYSCACEPG 1578
            C     CV    S TC C  G+ G  C     C   PC   A CV   + K  SC C  G
Sbjct: 193  CQHGGTCVDKIGSYTCICPPGKTGLICNFDDECASNPCSENATCVTSFSGKA-SCICNSG 251

Query: 1579 YTLTTSGCIESGKEECPGG---WWGGSAC----GPCACDVTRGY-HPHCNKENGKCHCKE 1630
            +  T   C +   +EC G     + G  C    G   CD   G+    C     +C    
Sbjct: 252  W--TGKNC-DVDIKECEGDSSPCYHGGTCRDIPGSFVCDCVPGFAGARCEDNINECESNP 308

Query: 1631 -NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689
              H           C C + G     C+    +C   P + G  C      Y+  T   G
Sbjct: 309  CVHGLCLDYQNKFECAC-SKGYTGRLCDVEINECDSNPCLNGGQCHDGLGNYS-CTCQVG 366

Query: 1690 -----CEVVYDGC 1697
                 C+  YD C
Sbjct: 367  YVGEICQTNYDDC 379



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            K     S+PCY+G  C D+  +++CDC  G  G  C D+
Sbjct: 262  KECEGDSSPCYHGGTCRDIPGSFVCDCVPGFAGARCEDN 300



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C S+PC NG  C D  + Y+C C  G +G  C
Sbjct: 448  CETEIDECESSPCQNGGTCKDKINGYVCICPPGASGTHC 486



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 7/63 (11%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DGMLSFNPL 1369
            C S+PC +G  C D  +TY C C +G TG  C     + +  P + GG   D + S++  
Sbjct: 645  CQSSPCVHGGSCIDGINTYTCQCPKGFTGPRCEIHINECSSDPCQHGGTCSDRIGSYSCY 704

Query: 1370 LRP 1372
             RP
Sbjct: 705  CRP 707



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  + + C S PC NG +C D    Y C C+ G+ G+ C
Sbjct: 334  CDVEINECDSNPCLNGGQCHDGLGNYSCTCQVGYVGEIC 372



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 8/73 (10%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC--RSGSQCVARREG--GILCQ---- 1090
            + ++TCQCP+GFTG  CE  + + S +    G  C  R GS     R G  G  CQ    
Sbjct: 660  INTYTCQCPKGFTGPRCEIHINECSSDPCQHGGTCSDRIGSYSCYCRPGYTGSNCQHPLD 719

Query: 1091 GCSIDAAYTTAVC 1103
             C+ D     A C
Sbjct: 720  RCANDPCRNGATC 732



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 16/39 (41%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+  PC  GA C D    Y C C  G TGK+C
Sbjct: 795  CRTNIDECAKGPCKYGATCHDAVANYTCTCTAGFTGKNC 833



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 17/39 (43%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC NG EC D    Y C C  G +G DC
Sbjct: 948  CDLNINECLSYPCRNGGECKDGAGEYTCLCPHGFSGDDC 986



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 60/226 (26%), Positives = 81/226 (35%), Gaps = 35/226 (15%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC---GAARCVPDQTPK 1569
            +C+   C    +C       TC C  G  G  C   V  C   PC   G  R V +    
Sbjct: 954  ECLSYPCRNGGECKDGAGEYTCLCPHGFSGDDCERRVYTCSDQPCLNSGTCRTVHNT--- 1010

Query: 1570 GYSCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHC 1628
             Y+C+C PG  +    C E  K+EC       G  C     D    Y   C       +C
Sbjct: 1011 -YNCSCRPG--VYGKQC-EWNKDECLSAPCRNGGTC----IDGYGSYSCKCPLGFAGANC 1062

Query: 1629 KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNS 1688
            +E+        ECL   C   GS          +C C   +IG+ C+        V PN 
Sbjct: 1063 EES------INECLSQPCKNGGSCRDIVNGY--KCDCPSKMIGKNCETVVKDQCPV-PN- 1112

Query: 1689 GCEVVYDG--C-PRSFAGGVWWPRT--KFGVETITDCPP-GSSGRA 1728
             C   +DG  C P+       W  T    G+E  ++C     SG+A
Sbjct: 1113 -CAKKFDGGKCNPKCNTHECNWDGTTCSLGIEPWSNCTTVTKSGKA 1157



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S PC  G+ C DL + Y+C C +G+ GK C
Sbjct: 833  CDININECASNPCQRGS-CLDLVNGYLCSCPKGYIGKHC 870



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   CS  PC N   C  + +TY C C+ G  GK C
Sbjct: 986  CERRVYTCSDQPCLNSGTCRTVHNTYNCSCRPGVYGKQC 1024



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 47/196 (23%), Positives = 69/196 (35%), Gaps = 25/196 (12%)

Query: 1513 SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPK 1569
            ++ +C+ + C     C+  + S +C C  G  G  C   ++ C   PC       D    
Sbjct: 1027 NKDECLSAPCRNGGTCIDGYGSYSCKCPLGFAGANCEESINECLSQPCKNGGSCRD-IVN 1085

Query: 1570 GYSCACEPGYTLTTSGCIESGKEECP----GGWWGGSACGPCACDVTRGYHPHCNKENGK 1625
            GY C C     +    C    K++CP       + G  C P  C+     H  CN +   
Sbjct: 1086 GYKCDCPS--KMIGKNCETVVKDQCPVPNCAKKFDGGKCNP-KCNT----H-ECNWDGTT 1137

Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQC-----HCRPGVIGRACDA-C 1677
            C      +    T       CY   + N  C  E  TG C      C+P V     D  C
Sbjct: 1138 CSLGIEPWSNCTTVTKSGKACYQVFA-NGVCDRECNTGGCLFDGFDCKPSVPKCGADKYC 1196

Query: 1678 ANAYAEVTPNSGCEVV 1693
            A  +A    ++ C  V
Sbjct: 1197 AARFANAECDAICNNV 1212



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 17/43 (39%), Positives = 19/43 (44%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C      C+S PC N   C D    Y C C  G TGK C  +T
Sbjct: 372  CQTNYDDCASNPCQNDGTCQDGIAQYTCLCPLGFTGKSCETNT 414



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 6/47 (12%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            + SF CQCP GFTG  CET + +  CE     S C++G  C  +  G
Sbjct: 432  INSFRCQCPLGFTGNRCETEIDE--CE----SSPCQNGGTCKDKING 472



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 14/31 (45%), Positives = 19/31 (61%)

Query: 1319 SAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            S PC NG  CS+++  Y+C C  G  G DC+
Sbjct: 148  SQPCQNGGTCSNVYGGYMCRCITGWDGADCS 178



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 16/89 (17%)

Query: 1002 CVHEPCLNFEECLTVLKFGNAS---GFV------NSDSVLFRP-------IYPVTSFTCQ 1045
            C  +PCLN   C TV    N S   G        N D  L  P       I    S++C+
Sbjct: 993  CSDQPCLNSGTCRTVHNTYNCSCRPGVYGKQCEWNKDECLSAPCRNGGTCIDGYGSYSCK 1052

Query: 1046 CPEGFTGVNCETILTKASCEVDGDGSICR 1074
            CP GF G NCE  + +   +   +G  CR
Sbjct: 1053 CPLGFAGANCEESINECLSQPCKNGGSCR 1081



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 41/176 (23%), Positives = 62/176 (35%), Gaps = 21/176 (11%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570
            CQ+   C         +C+T WD + C+        +C        C       D+    
Sbjct: 151  CQNGGTCSNVYGGYMCRCITGWDGADCSVNI----DECKQNDPFPRCQHGGTCVDKI-GS 205

Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSA-C-----GPCACDVTRGY-HPHCNKEN 1623
            Y+C C PG T    G I +  +EC       +A C     G  +C    G+   +C+ + 
Sbjct: 206  YTCICPPGKT----GLICNFDDECASNPCSENATCVTSFSGKASCICNSGWTGKNCDVDI 261

Query: 1624 GKCHCKENHYKPEGTAECLP----CQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
             +C    +     GT   +P    C C   G   + CE    +C   P V G   D
Sbjct: 262  KECEGDSSPCYHGGTCRDIPGSFVCDC-VPGFAGARCEDNINECESNPCVHGLCLD 316



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C    + C +  C NG  C D  +TY C C  G TG  C     +    P R GG
Sbjct: 486  CENDPNDCPANACQNGGVCIDGMNTYSCKCHPGFTGFSCGVPVNECASSPCRNGG 540



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A C +  + C S PC +G  C D  + + C C +G+TG+ C
Sbjct: 295  ARCEDNINECESNPCVHGL-CLDYQNKFECACSKGYTGRLC 334



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 9/66 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  + C+C +G+TG NCE  +   SC +D     C++G+ CV+       CQ C     Y
Sbjct: 546  VAQYYCRCRDGYTGKNCEVRID--SC-ID---HTCQNGASCVSSTPYAYSCQ-CK--PGY 596

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 597  TGQYCE 602



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 9/83 (10%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQ-GCSIDAA 1097
            + S++C C  G+TG NC+  L +  C  D     CR+G+ C  RR G  L    C     
Sbjct: 698  IGSYSCYCRPGYTGSNCQHPLDR--CANDP----CRNGATC--RRTGEDLSDFHCECPLG 749

Query: 1098 YTTAVCELRARSFPVSSFLTFPG 1120
            Y   +C+++  S  V+  +   G
Sbjct: 750  YKGTICDVKEVSCAVAGTICANG 772



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 35/123 (28%), Positives = 45/123 (36%), Gaps = 14/123 (11%)

Query: 1509 DGCQSRA-DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            D C+ R   C    C     C T  ++  C+C  G  G QC      C   PC     C+
Sbjct: 984  DDCERRVYTCSDQPCLNSGTCRTVHNTYNCSCRPGVYGKQCEWNKDECLSAPCRNGGTCI 1043

Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC-NKE 1622
                   YSC C  G+    + C ES  E        G +C     D+  GY   C +K 
Sbjct: 1044 DGY--GSYSCKCPLGF--AGANCEESINECLSQPCKNGGSCR----DIVNGYKCDCPSKM 1095

Query: 1623 NGK 1625
             GK
Sbjct: 1096 IGK 1098



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 1/47 (2%)

Query: 1303 DNGTLAGCPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348
            D  T   C  +   C    C NGA C S     Y C CK G+TG+ C
Sbjct: 555  DGYTGKNCEVRIDSCIDHTCQNGASCVSSTPYAYSCQCKPGYTGQYC 601



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C++ PC NGA C D  + +IC C  G TG  C
Sbjct: 601  CETDVDECAARPCVNGA-CVDGVNGFICRCDPGFTGDRC 638



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 10/71 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            + +++C+C  GFTG +C   + + +       S CR+G  C    E G+    C     Y
Sbjct: 508  MNTYSCKCHPGFTGFSCGVPVNECA------SSPCRNGGTC----EDGVAQYYCRCRDGY 557

Query: 1099 TTAVCELRARS 1109
            T   CE+R  S
Sbjct: 558  TGKNCEVRIDS 568



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 5/53 (9%)

Query: 1300 YVADNGTLAGCPEKRSRCSSAPCYNGAEC----SDLWDTYICDCKEGHTGKDC 1348
            Y     T + C     RC++ PC NGA C     DL D + C+C  G+ G  C
Sbjct: 704  YCRPGYTGSNCQHPLDRCANDPCRNGATCRRTGEDLSD-FHCECPLGYKGTIC 755



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+  PC N   C D  +++ C C  G TG  C
Sbjct: 410  CETNTNECAGNPCMNMGTCIDGINSFRCQCPLGFTGNRC 448



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  +TC CP GFTG +CET   + +      G+ C +   C+     GI    C     +
Sbjct: 394  IAQYTCLCPLGFTGKSCETNTNECA------GNPCMNMGTCI----DGINSFRCQCPLGF 443

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 444  TGNRCE 449



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 15/44 (34%), Positives = 17/44 (38%)

Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            GT+    E     +   C NG  C D      C CK G TG  C
Sbjct: 752  GTICDVKEVSCAVAGTICANGGTCFDSNGVQSCTCKPGFTGSYC 795



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 11/69 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V ++TC C  GFTG NC+  + + +       + C+ GS C+    G +    CS    Y
Sbjct: 817  VANYTCTCTAGFTGKNCDININECA------SNPCQRGS-CLDLVNGYL----CSCPKGY 865

Query: 1099 TTAVCELRA 1107
                CE+ A
Sbjct: 866  IGKHCEVNA 874



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 8/45 (17%)

Query: 1039 VTSFT----CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079
            VTSF+    C C  G+TG NC+  +     E +GD S C  G  C
Sbjct: 237  VTSFSGKASCICNSGWTGKNCDVDIK----ECEGDSSPCYHGGTC 277



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 14/55 (25%), Positives = 27/55 (49%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSID 1095
            +++CQC  G+TG  CET + + +     +G+     +  + R + G     C I+
Sbjct: 587  AYSCQCKPGYTGQYCETDVDECAARPCVNGACVDGVNGFICRCDPGFTGDRCQIN 641



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/67 (29%), Positives = 27/67 (40%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  F C+C  GFTG  C+  +    C+     S C  G  C+     GI    C     +
Sbjct: 622  VNGFICRCDPGFTGDRCQ--INVDDCQ----SSPCVHGGSCI----DGINTYTCQCPKGF 671

Query: 1099 TTAVCEL 1105
            T   CE+
Sbjct: 672  TGPRCEI 678


>SB_18364| Best HMM Match : Cadherin (HMM E-Value=3e-12)
          Length = 104

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 5/94 (5%)

Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRL 225
           D PV A + A+D D+GAN  + Y+I  G     F I DS SG +S+   L Y+Q  +Y +
Sbjct: 5   DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGAISVAGRLSYKQRNNYSV 62

Query: 226 VIRAQDGGSPSRSNTTQLLINIRDV--NDNAPRF 257
           V++  DGGS +  +   +LI++     N NAP F
Sbjct: 63  VVKVTDGGSLALESRAIVLIDVTPTTENRNAPVF 96



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 8/98 (8%)

Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           TPV T+ A+D D   + RL Y I  G   G F I   +  G I+VA  L +KQ   Y + 
Sbjct: 6   TPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GAISVAGRLSYKQRNNYSVV 63

Query: 441 VSATDSGGRS--DTAMVQINITDA--NNYAPVFENAPY 474
           V  TD G  +    A+V I++T    N  APVF +  Y
Sbjct: 64  VKVTDGGSLALESRAIVLIDVTPTTENRNAPVFASVQY 101



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 9/107 (8%)

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A I T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+    L  
Sbjct: 2   AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISVAGRLSY 54

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV--NDNEPVFKQQLY 586
           +  + Y + V   DGG  +L     V I V     N N PVF    Y
Sbjct: 55  KQRNNYSVVVKVTDGGSLALESRAIVLIDVTPTTENRNAPVFASVQY 101



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 5/99 (5%)

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVAT 652
           A + T V+ V A+D D+G NGR+ Y ++      G F I D +SG I     L  +    
Sbjct: 2   AAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISVAGRLSYKQRNN 59

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDI--NDSPPVFES 689
           + +     DGG+    S  IV I +     N + PVF S
Sbjct: 60  YSVVVKVTDGGSLALESRAIVLIDVTPTTENRNAPVFAS 98



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 4/67 (5%)

Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
           +  V A D D G N  L Y++    + G+  +    D  SG +  +G+L  + +  Y ++
Sbjct: 8   VATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISVAGRLSYKQRNNYSVV 63

Query: 336 VTATDGG 342
           V  TDGG
Sbjct: 64  VKVTDGG 70


>SB_12265| Best HMM Match : Cadherin (HMM E-Value=1.3e-10)
          Length = 110

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 3/82 (3%)

Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRL 225
           D PV A + A+D D+GAN  + Y+I  G     F I DS SG +SL   L Y Q  +Y +
Sbjct: 5   DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIV 62

Query: 226 VIRAQDGGSPSRSNTTQLLINI 247
           V+   DGGSP+  +   ++I++
Sbjct: 63  VVNVTDGGSPALKSRAMVVIDV 84



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 36/102 (35%), Positives = 49/102 (48%), Gaps = 12/102 (11%)

Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           TPV T+ A+D D   + RL Y I  G   G F I   +  G I++A  L + Q   Y++ 
Sbjct: 6   TPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GAISLAGMLSYNQRNNYIVV 63

Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480
           V+ TD G  +    AMV I++T      P   N  Y  SV E
Sbjct: 64  VNVTDGGSPALKSRAMVVIDVT------PKPRNLTYDVSVLE 99



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 7/90 (7%)

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A I T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+   +L  
Sbjct: 2   AAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSY 54

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
              + Y++ V   DGG P+L     V I V
Sbjct: 55  NQRNNYIVVVNVTDGGSPALKSRAMVVIDV 84



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVAT 652
           A + T V+ V A+D D+G NGR+ Y ++      G F I D +SG I     L       
Sbjct: 2   AAIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQRNN 59

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKI 677
           + +     DGG+P   S  +V I +
Sbjct: 60  YIVVVNVTDGGSPALKSRAMVVIDV 84



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
           +  V A D D G N  L Y++    + G+  +    D  SG +  +G L    +  Y ++
Sbjct: 8   VATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQRNNYIVV 63

Query: 336 VTATDGGDPPRSATA 350
           V  TDGG P   + A
Sbjct: 64  VNVTDGGSPALKSRA 78


>SB_49765| Best HMM Match : EGF (HMM E-Value=0)
          Length = 508

 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 19/179 (10%)

Query: 1506 NVRDGCQSRADCMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQCVSACELGPCGAARCV 1563
            ++R+   +R  C+ S C   S C  + D    TCTC  G  G  C +   L PC ++ C 
Sbjct: 110  DIREDTVTRP-CVSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHCDTVIPLKPCDSSPCS 168

Query: 1564 PD------QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWG-GSACGPCACDVTRGYH 1616
                    Q  K Y+C C PGYT     C     + C       GS C        + Y 
Sbjct: 169  NGGVCNNTQDGKNYTCTCSPGYT--GRHCDTVIPKPCDSSPCNNGSVCNNTQDG--KNYT 224

Query: 1617 PHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
              C+      HC  +   P+    C+   C      N++ +     C C PG  GR CD
Sbjct: 225  CTCSPGYTGRHC--DTVIPKA---CVSSPCSNGSICNNTQDGKNYTCTCSPGYTGRHCD 278



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 7/103 (6%)

Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061
            C   P      C TV+          S+  +        ++TC C  G+TG +C+T++ K
Sbjct: 142  CTCSPGYTGRHCDTVIPLKPCDSSPCSNGGVCNNTQDGKNYTCTCSPGYTGRHCDTVIPK 201

Query: 1062 ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
              C    D S C +GS C   ++G      C+    YT   C+
Sbjct: 202  -PC----DSSPCNNGSVCNNTQDGKNYT--CTCSPGYTGRHCD 237



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            C S+PC NG+ C++  D   Y C C  G+TG+ C
Sbjct: 203  CDSSPCNNGSVCNNTQDGKNYTCTCSPGYTGRHC 236



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            C S+PC NG+ C++  D   Y C C  G+TG+ C
Sbjct: 310  CDSSPCSNGSVCNNTQDGKNYTCSCSYGYTGRHC 343



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            C S+PC NG  C++  D   Y C C  G+TG+ C
Sbjct: 162  CDSSPCSNGGVCNNTQDGKNYTCTCSPGYTGRHC 195



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            C S+PC NG+ C++  D   Y C C  G+TG+ C
Sbjct: 120  CVSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHC 153



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            C S+PC NG+ C++  D   Y C C  G+TG+ C
Sbjct: 244  CVSSPCSNGSICNNTQDGKNYTCTCSPGYTGRHC 277



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 6/64 (9%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            ++TC C  G+TG +C+T++    C    D S C +G  C   ++G      C+    YT 
Sbjct: 139  NYTCTCSPGYTGRHCDTVIPLKPC----DSSPCSNGGVCNNTQDGKNYT--CTCSPGYTG 192

Query: 1101 AVCE 1104
              C+
Sbjct: 193  RHCD 196



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 8/103 (7%)

Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061
            C   P      C TV+     S   N+ SV         ++TC C  G+TG +C+T++ K
Sbjct: 184  CTCSPGYTGRHCDTVIPKPCDSSPCNNGSVC-NNTQDGKNYTCTCSPGYTGRHCDTVIPK 242

Query: 1062 ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
            A        S C +GS C   ++G      C+    YT   C+
Sbjct: 243  ACV-----SSPCSNGSICNNTQDGKNYT--CTCSPGYTGRHCD 278



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 6/50 (12%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG-GILC 1089
            ++TC C  G+TG +C T L K SCE      +C+ G  C+   +G G +C
Sbjct: 329  NYTCSCSYGYTGRHCNT-LKKLSCE----DIVCQYGGTCITINDGIGCVC 373



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 28/90 (31%), Positives = 34/90 (37%), Gaps = 13/90 (14%)

Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGC 1697
            T  C+   C      N++ +     C C PG  GR CD        V P   C    D  
Sbjct: 117  TRPCVSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHCDT-------VIPLKPC----DSS 165

Query: 1698 PRSFAGGVWWPRTKFGVETITDCPPGSSGR 1727
            P S  GGV    T+ G      C PG +GR
Sbjct: 166  PCS-NGGV-CNNTQDGKNYTCTCSPGYTGR 193


>SB_40116| Best HMM Match : EGF (HMM E-Value=0)
          Length = 340

 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 52/169 (30%), Positives = 67/169 (39%), Gaps = 30/169 (17%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  + C     CV   D  TC C  G  G  C   V+ C+  PC   A CV +Q   G+
Sbjct: 4    DCHPNPCQYGGTCVDGLDDFTCLCVPGTTGKICHINVNYCDSEPCMNNATCVDEQ--DGF 61

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC-NKENG-KCHCK 1629
            +C C PGYT  T  C +   +EC        A  PC      G    C N ENG +C C 
Sbjct: 62   TCICAPGYTGPT--C-DGDIDEC--------AFNPC----LNG--AECINLENGFECVCL 104

Query: 1630 ENHYKPE---GTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
              +          +C P  C   G      +    +C C PG +G  C+
Sbjct: 105  PGYTGKRCGIDIDDCTPSPCINGG--RCIDQVNDYECQCLPGFVGDNCE 151



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 46/184 (25%), Positives = 68/184 (36%), Gaps = 25/184 (13%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C   ++C+   +   C C  G  G +C   +  C   PC    RC+ DQ    Y
Sbjct: 80   ECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGGRCI-DQV-NDY 137

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGP------CACDVTRGY------HPH 1618
             C C PG+      C E+  ++C       G+ C        C C +  GY      H  
Sbjct: 138  ECQCLPGFV--GDNC-ETNVDDCADNPCLNGATCIDGVNDYYCVCAI--GYYSKNCEHIS 192

Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678
            CN+ +       + +  E T+ C  C C   G+   S       C C  G  G  C+   
Sbjct: 193  CNRFSVVVLLICDLFLSE-TSTCTDCTCENGGTCGVSSVYGHWFCVCPKGFKGERCEIAD 251

Query: 1679 NAYA 1682
            N  A
Sbjct: 252  NGCA 255



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C      C+  PC NGAEC +L + + C C  G+TGK C     D T  P   GG
Sbjct: 74   CDGDIDECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGG 128



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348
            C    + C++ PC NG  C  D    Y C C+EG TGK+C
Sbjct: 247  CEIADNGCATKPCQNGGSCCQDPVKGYSCICREGFTGKNC 286



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C S PC N A C D  D + C C  G+TG  C
Sbjct: 43   CDSEPCMNNATCVDEQDGFTCICAPGYTGPTC 74



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 6/65 (9%)

Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343
            CI D   D++   L  +V DN     C      C+  PC NGA C D  + Y C C  G+
Sbjct: 130  CI-DQVNDYECQCLPGFVGDN-----CETNVDDCADNPCLNGATCIDGVNDYYCVCAIGY 183

Query: 1344 TGKDC 1348
              K+C
Sbjct: 184  YSKNC 188



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+ +PC NG  C D  + Y C C  G  G +C
Sbjct: 119  CTPSPCINGGRCIDQVNDYECQCLPGFVGDNC 150



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 5/48 (10%)

Query: 1537 CTCEAGRVGPQCVSA---CELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
            C C  G  G +C  A   C   PC     C  D   KGYSC C  G+T
Sbjct: 236  CVCPKGFKGERCEIADNGCATKPCQNGGSCCQDPV-KGYSCICREGFT 282



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/32 (43%), Positives = 15/32 (46%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C   PC  G  C D  D + C C  G TGK C
Sbjct: 5    CHPNPCQYGGTCVDGLDDFTCLCVPGTTGKIC 36



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 12/19 (63%), Positives = 14/19 (73%)

Query: 1038 PVTSFTCQCPEGFTGVNCE 1056
            PV  ++C C EGFTG NCE
Sbjct: 269  PVKGYSCICREGFTGKNCE 287



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            R I  V  + CQC  GF G NCET +   +     +G+ C  G
Sbjct: 129  RCIDQVNDYECQCLPGFVGDNCETNVDDCADNPCLNGATCIDG 171


>SB_471| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 587

 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 34/108 (31%), Positives = 43/108 (39%), Gaps = 11/108 (10%)

Query: 1606 PCACDVTRGYHPHCNKENGKCHCKENHYKPE---------GTAECLPCQCYAAGSENSSC 1656
            PC CD        C+K  G+C C+ N    +         G   C  C+C   GS +  C
Sbjct: 340  PCECDPKGALDASCSKFGGQCTCRRNVVGRKCDRCMASYTGFPNCRKCECSPVGSVSPDC 399

Query: 1657 EAATGQCHCRPGVIGRACDACANAYAEVTPN-SGCEVVYDGCPRSFAG 1703
            +  TG C C  G  GR CD CA+      PN   C     G   +F G
Sbjct: 400  D-VTGHCTCTRGFGGRKCDRCASYGYYGYPNCKACNCDTRGSLSTFCG 446



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 52/195 (26%), Positives = 69/195 (35%), Gaps = 32/195 (16%)

Query: 1516 DCMLSICPPYSKCVTSWD-SSTCTCEAGRVGPQCVSACELGPCGAARCVPDQ--TPKGYS 1572
            +C    C P        D +  CTC  G  G +C      G  G   C      T    S
Sbjct: 383  NCRKCECSPVGSVSPDCDVTGHCTCTRGFGGRKCDRCASYGYYGYPNCKACNCDTRGSLS 442

Query: 1573 CACEPGYTLTTSGCIESGK-EECPGGWWGGSACGPCACD-----VTRGYHPHCNKENG-K 1625
              C            E  K ++C  G++    C  C C+     +  G    C   N  K
Sbjct: 443  TFCGSWGQCQCRMNFEGLKCDQCRVGYYDFPRCKQCGCNPAGIRLLPGQQNTCGNGNDTK 502

Query: 1626 CHCKEN------------HY-----KPEGTAECLPCQCYAAGSENS--SCEAATGQCHCR 1666
            C CKEN            H+      P+G   C PC C   G+  S   C+   G+C+C+
Sbjct: 503  CTCKENVQGAECEQCKSMHFGLSIFNPKG---CRPCGCNLNGTLGSIGDCDKDHGRCNCK 559

Query: 1667 PGVIGRACDACANAY 1681
              V GR C  CA+ Y
Sbjct: 560  AHVTGRECGRCADGY 574



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 34/127 (26%), Positives = 42/127 (33%), Gaps = 15/127 (11%)

Query: 1568 PKGY---SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG 1624
            PKG    SC+   G        +    + C   + G   C  C C       P C+   G
Sbjct: 345  PKGALDASCSKFGGQCTCRRNVVGRKCDRCMASYTGFPNCRKCECSPVGSVSPDCDV-TG 403

Query: 1625 KCHCKENH----------YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
             C C              Y   G   C  C C   GS ++ C  + GQC CR    G  C
Sbjct: 404  HCTCTRGFGGRKCDRCASYGYYGYPNCKACNCDTRGSLSTFC-GSWGQCQCRMNFEGLKC 462

Query: 1675 DACANAY 1681
            D C   Y
Sbjct: 463  DQCRVGY 469



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 31/128 (24%), Positives = 51/128 (39%), Gaps = 12/128 (9%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG----PQCVSACELGPCGAARCVPDQ 1566
            C +R   + + C  + +C    +     C+  RVG    P+C   C   P G  R +P Q
Sbjct: 435  CDTRGS-LSTFCGSWGQCQCRMNFEGLKCDQCRVGYYDFPRC-KQCGCNPAGI-RLLPGQ 491

Query: 1567 TP---KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV--TRGYHPHCNK 1621
                  G    C     +  + C +          +    C PC C++  T G    C+K
Sbjct: 492  QNTCGNGNDTKCTCKENVQGAECEQCKSMHFGLSIFNPKGCRPCGCNLNGTLGSIGDCDK 551

Query: 1622 ENGKCHCK 1629
            ++G+C+CK
Sbjct: 552  DHGRCNCK 559


>SB_43550| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 1182

 Score = 56.0 bits (129), Expect = 4e-07
 Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 21/187 (11%)

Query: 1575 CEP--GYTLTTSGCIESGKEECPGGWWGGS--ACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            C+P  G     S  I    + C  G +G S   C  C CD        CN   G+C C+ 
Sbjct: 248  CDPIGGQCKCKSNVIGQRCDRCAPGSFGFSNKGCSACDCDRIGAIDNFCNILTGQCQCRN 307

Query: 1631 -------NHYKPE--GTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRACDACA-N 1679
                   +   P   G   C PC+CY      SSC   TG C  C+   +G+ C+ACA  
Sbjct: 308  WASGRQCSLCPPNMWGFPLCRPCRCY---GHASSCNPKTGVCVDCQHNTVGKNCEACAVG 364

Query: 1680 AYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITD---CPPGSSGRATRTCDETK 1736
             Y   T  +  +     CP   +G  +         T      C     G   R C+E  
Sbjct: 365  FYGIATKGTPNDCKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDKCQVGYTGRQCEECA 424

Query: 1737 DVPWQDP 1743
            D  + +P
Sbjct: 425  DGYYGNP 431



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 46/170 (27%), Positives = 64/170 (37%), Gaps = 20/170 (11%)

Query: 1539 CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIE-----SGKEE 1593
            C+ G  G QC   C  G  G    VP  + K  SC      T++  GC +      G   
Sbjct: 411  CQVGYTGRQC-EECADGYYGNP-LVPGGSCKPCSCNNNIDPTVSGKGCQQCDCCIEGSLR 468

Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK-----------ENHYKPEGTAECL 1642
                   G  C  C C +       C++  G+C CK           E+++       C 
Sbjct: 469  SMCNQVSGKGCQQCDCCIEGSLRSMCSQITGQCQCKAGFGGPRCCECEDNFWGSPPDGCS 528

Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692
             C    AGS +  C+  TG+C C+ G IG   D CA   +   P   CE+
Sbjct: 529  ACNGNPAGSGHLQCDRDTGKCLCKVGHIGDKWDMCAADTSGKMPQ--CEI 576



 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 47/170 (27%), Positives = 63/170 (37%), Gaps = 30/170 (17%)

Query: 1533 DSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSC-ACEPGYTLTTSGCIESGK 1591
            D   C C  G  G +   +C +            TP    C  C+ GYT     C     
Sbjct: 376  DCKRCQCPGGSSGNKFSESCYVDT--------STTPPSVLCDKCQVGYT--GRQC----- 420

Query: 1592 EECPGGWWG-----GSACGPCACDVTRGYHPHCN-KENGKCHC-----KENHYKPEGTAE 1640
            EEC  G++G     G +C PC+C+      P  + K   +C C       +         
Sbjct: 421  EECADGYYGNPLVPGGSCKPCSCN--NNIDPTVSGKGCQQCDCCIEGSLRSMCNQVSGKG 478

Query: 1641 CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
            C  C C   GS  S C   TGQC C+ G  G  C  C + +   +P  GC
Sbjct: 479  CQQCDCCIEGSLRSMCSQITGQCQCKAGFGGPRCCECEDNFWG-SPPDGC 527



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 6/65 (9%)

Query: 1631 NHYKPEGTAECLPCQCYAAGSENSS-----CEAATGQCHCRPGVIGRACDACANAYAEVT 1685
            N  K +G      C C   G++  +     C+   GQC C+  VIG+ CD CA      +
Sbjct: 218  NKNKYDGGNNDDTCNCDPKGTQRDANGTLVCDPIGGQCKCKSNVIGQRCDRCAPGSFGFS 277

Query: 1686 PNSGC 1690
             N GC
Sbjct: 278  -NKGC 281


>SB_9705| Best HMM Match : Cadherin (HMM E-Value=0.013)
          Length = 130

 Score = 55.2 bits (127), Expect = 7e-07
 Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 14/134 (10%)

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           L+ E+ A H+++    D G+PP+S     +I + ++ND P          Y+ EN+PI +
Sbjct: 8   LNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDKPRGLLLS--NQYVKENAPINS 65

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            IG+  A D D G   V  +S+   DD+  F ++         LV     DYE+  K ++
Sbjct: 66  VIGQFSARDEDNGQRLV--FSL-DNDDNGRFRVD-----GLGRLVKAKQTDYET-SKAHQ 116

Query: 765 LVIRA---ASPPLW 775
           + +R     +P LW
Sbjct: 117 ITVRVTDDGNPRLW 130



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 10/130 (7%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
           L+YE    + + +R  D GSP +S      I + +VND  PR    L  + V EN PI  
Sbjct: 8   LNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDK-PRGLL-LSNQYVKENAPINS 65

Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
            I +  A D D G    L +++ D D  G       +D   G +  + Q D ET   +Q+
Sbjct: 66  VIGQFSARDEDNG--QRLVFSL-DNDDNGR----FRVD-GLGRLVKAKQTDYETSKAHQI 117

Query: 335 LVTATDGGDP 344
            V  TD G+P
Sbjct: 118 TVRVTDDGNP 127



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 31/126 (24%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX-XXXFMPGQYEVELAEDEPP 381
           +L+ E  A + + V  TD G PP+S                    +  QY   + E+ P 
Sbjct: 7   KLNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDKPRGLLLSNQY---VKENAPI 63

Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            + +   +A D D   RL + +   +  GRF +   +G G +  A+  D++  + + +TV
Sbjct: 64  NSVIGQFSARDEDNGQRLVFSL-DNDDNGRFRV---DGLGRLVKAKQTDYETSKAHQITV 119

Query: 442 SATDSG 447
             TD G
Sbjct: 120 RVTDDG 125



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 7/127 (5%)

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           L+ E  + + + V   D G P  S   +  I+V +VND        L    + E+A + +
Sbjct: 8   LNYENNAYHNIRVRTTDSGSPPKSFERNFNITVNNVNDKPRGL--LLSNQYVKENAPINS 65

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            + Q  A D D G   R+ + LD  D   G F +D    +++  K  D E+   H +   
Sbjct: 66  VIGQFSARDEDNG--QRLVFSLDNDD--NGRFRVDGLGRLVKA-KQTDYETSKAHQITVR 120

Query: 659 AIDGGTP 665
             D G P
Sbjct: 121 VTDDGNP 127



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 11/131 (8%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           L+ E  A + + V+ TD  SP          I VN ++D       S +     V E+  
Sbjct: 8   LNYENNAYHNIRVRTTDSGSPPKS-FERNFNITVNNVNDKPRGLLLSNQY----VKENAP 62

Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
           +  N VI +  A D D G         +  +   +F +D L G +   K  DYE  ++++
Sbjct: 63  I--NSVIGQFSARDEDNGQRLVFS---LDNDDNGRFRVDGL-GRLVKAKQTDYETSKAHQ 116

Query: 225 LVIRAQDGGSP 235
           + +R  D G+P
Sbjct: 117 ITVRVTDDGNP 127


>SB_32282| Best HMM Match : Laminin_G_2 (HMM E-Value=0)
          Length = 897

 Score = 54.8 bits (126), Expect = 9e-07
 Identities = 45/134 (33%), Positives = 65/134 (48%), Gaps = 12/134 (8%)

Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHR--IHLKLKFATQTTSGLLLYNGRYNE 1150
            SI+AA   A    + R F  +S+++ P L R  R    L + F   +  GLLLY GR ++
Sbjct: 302  SIEAAEPNARSARQPR-FKGTSYMSLPRLPRSARTSFELSIMFKASSGDGLLLYGGRKDK 360

Query: 1151 RHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITM 1210
            R DFLAL L      R G   + F FS G   +++    N+    WH V +    R   +
Sbjct: 361  RKDFLALGL------RNG--HVEFRFSCGADIAQVRSRQNITLNQWHNVVVFRDKRDAHL 412

Query: 1211 ILDDCDKVL-SLAG 1223
            ++D+ D V  SL G
Sbjct: 413  MVDNGDLVTQSLKG 426



 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 33/212 (15%)

Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDC--ADSTGPPWRFGGDGMLSFNPLLRPIQLPWLN 1379
            C+NG  C    D Y C C  G+TG  C  A     P  F GDG + F       +L   N
Sbjct: 689  CFNGGTCQAKMDHYKCHCAVGYTGMMCERARRVSAP-TFAGDGFMKFKGSEILSRLSGKN 747

Query: 1380 A---LSIRTRQRDAFVMSIQLKS-------------GLLHYSYN----GETMYLPMATLS 1419
                   RT++    ++S+Q +S             G+L   Y+     ET+    ATL 
Sbjct: 748  TELEFLFRTQESSGLLLSVQKESVSHGDHITIGLIDGILEVRYDLGVGRETVIRSTATLD 807

Query: 1420 DGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGK--ILIGGLDTTAGLLAS 1477
            DG WH ++         + VD  ++      +A+  Q + +    + IGG  T      S
Sbjct: 808  DGYWHSVKFVRKSLAAYLKVDDEIKA----GIASDSQYRQLNSDVLFIGGAPTVDRRFMS 863

Query: 1478 DVGFFEGCIQDVRIGTAQ-SLLNRPTVRENVR 1508
             +    GC++D+ +G     L +  T  +NVR
Sbjct: 864  GL---VGCLKDLIVGDVPVDLASEVTSGQNVR 892



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 11/100 (11%)

Query: 1256 LDLTGPLQIGGLPN---IPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVAD---NGTLAG 1309
            +DL   L +GG+P    + S     +  F GC+  F +D + +DL+  + D   +  +  
Sbjct: 431  MDLKTRLFLGGVPRMRRVTSDAVPYHSGFTGCVKSFVVDGRMLDLSQALGDVVKSRQVEE 490

Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDC 1348
            C E R  C    C++ A C   +    IC C  G  G+ C
Sbjct: 491  CGESRD-CE---CHHNAPCHYAVSGEPICACPLGTYGRLC 526



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 14/44 (31%), Positives = 23/44 (52%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            + C C  G+TG+ CE     ++    GDG +   GS+ ++R  G
Sbjct: 702  YKCHCAVGYTGMMCERARRVSAPTFAGDGFMKFKGSEILSRLSG 745


>SB_22642| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1574

 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 40/145 (27%), Positives = 54/145 (37%), Gaps = 27/145 (18%)

Query: 1557 CGAARCVPDQTPKGYSCAC--EPGYTLTTSGCIESGK------EECPGGWWG-----GSA 1603
            C A  C P     G  C    +P   L    CI          + C  G++         
Sbjct: 1406 CIACNCDPTGGVNGGECEAKNDPAAGLVAGRCICKRNVGGVRCDRCKAGFFNLTTDNPDG 1465

Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKE------------NHYKPEGT-AECLPCQCYAAG 1650
            C  C C+   G    CN + G+C CK              ++    T A C  C C   G
Sbjct: 1466 CKACGCNPL-GTIGECNPDTGRCTCKRYVEGEDCDRCASEYWGLSSTPAGCSNCACDVGG 1524

Query: 1651 SENSSCEAATGQCHCRPGVIGRACD 1675
            S ++ C+  TGQC CR G+ GR C+
Sbjct: 1525 SYDNQCDKQTGQCRCRKGITGRQCE 1549



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 40/154 (25%), Positives = 56/154 (36%), Gaps = 16/154 (10%)

Query: 1539 CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGW 1598
            CE   VG  C     L     ++   D      +C C+P      +G +  G+ E     
Sbjct: 1376 CEHNTVGRNCERCKPLHYQDPSKKFSDPDAC-IACNCDP------TGGVNGGECEAKNDP 1428

Query: 1599 WGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEA 1658
              G   G C C    G    C++    C     +   +    C  C C   G+    C  
Sbjct: 1429 AAGLVAGRCICKRNVG-GVRCDR----CKAGFFNLTTDNPDGCKACGCNPLGTIGE-CNP 1482

Query: 1659 ATGQCHCRPGVIGRACDACANAY--AEVTPNSGC 1690
             TG+C C+  V G  CD CA+ Y     TP +GC
Sbjct: 1483 DTGRCTCKRYVEGEDCDRCASEYWGLSSTP-AGC 1515


>SB_2045| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1101

 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 47/176 (26%), Positives = 62/176 (35%), Gaps = 20/176 (11%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPG 1578
            C P+  CV   +  TCTC  G  G +C   +  C+  PC             Y C C  G
Sbjct: 843  CGPHGTCVDGVNRYTCTCHPGWNGTKCDIDIDECDPNPCLRGGQCHQTNNASYICTCPVG 902

Query: 1579 YTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638
            Y  T   C E+   EC       ++   C  D   GY   C       +C  N      +
Sbjct: 903  Y--TGQKC-ETEINECLSSSVKCTSGSTC-LDRLDGYECQCPPGLKGIYCSSN------S 952

Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC----DACANAYAEVTPNSGC 1690
            + C P  C    S N +       C C PG  GR C    D C ++      N+ C
Sbjct: 953  SWCEPNPCI---SGNCTDTGTNFTCLCNPGFTGRYCEIDIDECVSSPCGNVSNTKC 1005



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 19/39 (48%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C   PC NGA C DL   Y C C  G TGKDC
Sbjct: 586  CTTTTDECDPNPCKNGASCKDLHLDYNCSCPVGFTGKDC 624



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 62/247 (25%), Positives = 80/247 (32%), Gaps = 39/247 (15%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC------------VSACELGPC 1557
            C++  D C    C     C   +   TCTC  G  G QC            ++ C  GPC
Sbjct: 463  CETEIDLCEPEPCANGGSCTNFYTYYTCTCVPGYTGKQCAAGYTGTNCETNINECASGPC 522

Query: 1558 -GAARCVPDQTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRG 1614
                 CV +    GY C C  G+T     +   E     C  G           CD   G
Sbjct: 523  RNNGTCVDE--VNGYQCLCLQGFTGQRCETDIDECLTTPCLNGGTCHDEINNFRCDCPTG 580

Query: 1615 YH-PHCNKENGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCE-----AATGQC-- 1663
            Y+   C     +C    CK N    +       C C   G     CE        G C  
Sbjct: 581  YYGKTCTTTTDECDPNPCK-NGASCKDLHLDYNCSC-PVGFTGKDCEINIDDCTVGSCAG 638

Query: 1664 --HCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETIT-DC 1720
               C+ G+   +C  C   Y      + C+   D C  S          K GV   T +C
Sbjct: 639  TGTCKDGINDFSC-VCNTGYT----GAKCDSNIDDCAASGQPCQNGATCKDGVNQYTCEC 693

Query: 1721 PPGSSGR 1727
            P G +GR
Sbjct: 694  PLGFTGR 700



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/40 (40%), Positives = 21/40 (52%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C  +   C   PC NG  C++ +  Y C C  G+TGK CA
Sbjct: 463  CETEIDLCEPEPCANGGSCTNFYTYYTCTCVPGYTGKQCA 502



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C      C + PC NG  C D  + + CDC  G+ GK C  +T
Sbjct: 548  CETDIDECLTTPCLNGGTCHDEINNFRCDCPTGYYGKTCTTTT 590



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 42/170 (24%), Positives = 57/170 (33%), Gaps = 17/170 (10%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCG-AARCVPDQTPKGY 1571
            DC  + C   + CV    + TC C  G  G  C   ++ C   PC     CV +     Y
Sbjct: 708  DCASAACANGATCVDGIANYTCNCSIGYKGRHCGERINYCVTNPCKYQGTCVNEL--GYY 765

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP---CACDVTRGYH-PHCNKENGKCH 1627
             C C+ GY  T           C     G  A  P     C+   GY   +C  +   C 
Sbjct: 766  RCLCKEGYNGTNCEIDPCKWNPCQRN--GTCAVVPNTLYRCECKEGYSGRNCEIDIDDCD 823

Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIGRACD 1675
               N +  E +        Y     + +C     +  C C PG  G  CD
Sbjct: 824  PNNNIWNEENSNN---VGAYGFCGPHGTCVDGVNRYTCTCHPGWNGTKCD 870



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 3/53 (5%)

Query: 1299 SYVADNG-TLAGCPEKRSRCSSA--PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            S V + G T A C      C+++  PC NGA C D  + Y C+C  G TG+ C
Sbjct: 650  SCVCNTGYTGAKCDSNIDDCAASGQPCQNGATCKDGVNQYTCECPLGFTGRHC 702



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C+SA C NGA C D    Y C+C  G+ G+ C +
Sbjct: 709  CASAACANGATCVDGIANYTCNCSIGYKGRHCGE 742



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T   C    + C+S PC N   C D  + Y C C +G TG+ C
Sbjct: 506  TGTNCETNINECASGPCRNNGTCVDEVNGYQCLCLQGFTGQRC 548



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348
            C +  ++C  +PC N   C +   D Y C CK  +TGK+C
Sbjct: 424  CDQDLNKCRYSPCQNEGTCLNTGPDAYSCACKYKYTGKNC 463



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 8/58 (13%)

Query: 1528 CVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAA---RCVPDQTPKGYSCACEPGY 1579
            C  +  + TC C  G  G  C   +  C   PCG     +C+    P  YSC C P Y
Sbjct: 965  CTDTGTNFTCLCNPGFTGRYCEIDIDECVSSPCGNVSNTKCI--DLPGNYSCRCPPDY 1020



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 14/38 (36%), Positives = 21/38 (55%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            V  +TC+CP GFTG +CE  +   +     +G+ C  G
Sbjct: 686  VNQYTCECPLGFTGRHCEINIDDCASAACANGATCVDG 723



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 4/45 (8%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            S+ C CP G+TG  CET +     E       C SGS C+ R +G
Sbjct: 894  SYICTCPVGYTGQKCETEIN----ECLSSSVKCTSGSTCLDRLDG 934



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 3/46 (6%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348
            NGT   C      C   PC  G +C    + +YIC C  G+TG+ C
Sbjct: 865  NGTK--CDIDIDECDPNPCLRGGQCHQTNNASYICTCPVGYTGQKC 908



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 1/33 (3%)

Query: 1317 CSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348
            C   PC     C+ + +T Y C+CKEG++G++C
Sbjct: 783  CKWNPCQRNGTCAVVPNTLYRCECKEGYSGRNC 815



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 10/76 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            + +F C CP G+ G  C T  T   C    D + C++G+ C        L   CS    +
Sbjct: 570  INNFRCDCPTGYYGKTCTT--TTDEC----DPNPCKNGASCKDLH----LDYNCSCPVGF 619

Query: 1099 TTAVCELRARSFPVSS 1114
            T   CE+      V S
Sbjct: 620  TGKDCEINIDDCTVGS 635



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E+ + C + PC     C +    Y C CKEG+ G +C
Sbjct: 740  CGERINYCVTNPCKYQGTCVNELGYYRCLCKEGYNGTNC 778



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    S C   PC +G  C+D    + C C  G TG+ C
Sbjct: 948  CSSNSSWCEPNPCISG-NCTDTGTNFTCLCNPGFTGRYC 985



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 39/150 (26%), Positives = 52/150 (34%), Gaps = 24/150 (16%)

Query: 1537 CTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593
            C C+    G  C   ++ C   PC       +  P  YSCAC+  Y  T   C E+  + 
Sbjct: 413  CVCKPDWQGDNCDQDLNKCRYSPCQNEGTCLNTGPDAYSCACK--YKYTGKNC-ETEIDL 469

Query: 1594 C-PGGWWGGSACGP----CACDVTRGY-HPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647
            C P     G +C        C    GY    C       +C+ N        EC    C 
Sbjct: 470  CEPEPCANGGSCTNFYTYYTCTCVPGYTGKQCAAGYTGTNCETN------INECASGPC- 522

Query: 1648 AAGSENSSC--EAATGQCHCRPGVIGRACD 1675
                 N +C  E    QC C  G  G+ C+
Sbjct: 523  ---RNNGTCVDEVNGYQCLCLQGFTGQRCE 549



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 3/49 (6%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGD---GSICRSGSQCVARREG 1085
            T +TC C  G+TG  C    T  +CE + +      CR+   CV    G
Sbjct: 486  TYYTCTCVPGYTGKQCAAGYTGTNCETNINECASGPCRNNGTCVDEVNG 534



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 8/67 (11%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  F+C C  G+TG  C++ +   +      G  C++G+ C    + G+    C     +
Sbjct: 646  INDFSCVCNTGYTGAKCDSNIDDCA----ASGQPCQNGATC----KDGVNQYTCECPLGF 697

Query: 1099 TTAVCEL 1105
            T   CE+
Sbjct: 698  TGRHCEI 704



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 11/23 (47%), Positives = 17/23 (73%)

Query: 1041 SFTCQCPEGFTGVNCETILTKAS 1063
            +++C+CP  + G NCETI  +AS
Sbjct: 1011 NYSCRCPPDYEGANCETIKMEAS 1033



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            + C CP GFTG +CE  +    C V   GS C     C    + GI    C  +  YT A
Sbjct: 611  YNCSCPVGFTGKDCE--INIDDCTV---GS-CAGTGTC----KDGINDFSCVCNTGYTGA 660

Query: 1102 VCE 1104
             C+
Sbjct: 661  KCD 663



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 1310 CPEKRSRC--SSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C  + + C  SS  C +G+ C D  D Y C C  G  G  C+ ++
Sbjct: 908  CETEINECLSSSVKCTSGSTCLDRLDGYECQCPPGLKGIYCSSNS 952



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            T+FTC C  GFTG  CE  + +  C     G++  S ++C+    G   C+ C  D  Y 
Sbjct: 970  TNFTCLCNPGFTGRYCEIDIDE--CVSSPCGNV--SNTKCI-DLPGNYSCR-CPPD--YE 1021

Query: 1100 TAVCELRARSFPVSSFLTFP 1119
             A CE       VS+ L FP
Sbjct: 1022 GANCETIKMEASVSTVL-FP 1040


>SB_8580| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 426

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 41/119 (34%), Positives = 53/119 (44%), Gaps = 16/119 (13%)

Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELGP--CGA-AR 1561
            C    +C L+I  CP    CV +  S TC C+ G   V   C  +  C LG   C A A 
Sbjct: 202  CDDIDECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASAD 261

Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIES-----GKEECPGGWWGGSACGPCACDVTRGY 1615
            CV +     Y+C C+PGYTL  + CI++     G   CP      +  G   C   RGY
Sbjct: 262  CVNNNG--SYTCRCKPGYTLVNNTCIDTDECALGVATCPASADCVNNDGSYTCRCKRGY 318



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 13/100 (13%)

Query: 1507 VRDGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQCVSA--CELG--PCG 1558
            V + C+   +C L +  CP  + CV +  S TC C+ G   V   C+    C LG   C 
Sbjct: 239  VNNTCEDIDECALGVANCPASADCVNNNGSYTCRCKPGYTLVNNTCIDTDECALGVATCP 298

Query: 1559 A-ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597
            A A CV +     Y+C C+ GYTL    C +   +EC  G
Sbjct: 299  ASADCVNNDG--SYTCRCKRGYTLVNKTCKDI--DECALG 334



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 11/89 (12%)

Query: 1507 VRDGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELG--PCG 1558
            V + C    +C L +  CP  + CV +  S TC C+ G   V   C  +  C LG   C 
Sbjct: 280  VNNTCIDTDECALGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCKDIDECALGVATCP 339

Query: 1559 A-ARCVPDQTPKGYSCACEPGYTLTTSGC 1586
            A A CV +     Y+C C+ G+TL  + C
Sbjct: 340  ASADCVNNNG--SYTCRCKRGFTLVNNTC 366



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 37/156 (23%), Positives = 58/156 (37%), Gaps = 18/156 (11%)

Query: 1549 VSACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606
            V+ C   P  C     + + T   + C+C+PGYT   S  +     + P           
Sbjct: 152  VNECTETPYVCSGENSICENTDGSFKCSCKPGYTPKFSKAV----GDAPANLTSCDDIDE 207

Query: 1607 CACDV-TRGYHPHCNKENGK--CHCKENHYKPEGTAECL-PCQCYAAGSENSS-CEAATG 1661
            C  ++ T   + +C   +G   C CK  +     T E +  C    A    S+ C    G
Sbjct: 208  CKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCVNNNG 267

Query: 1662 Q--CHCRPG--VIGRAC---DACANAYAEVTPNSGC 1690
               C C+PG  ++   C   D CA   A    ++ C
Sbjct: 268  SYTCRCKPGYTLVNNTCIDTDECALGVATCPASADC 303


>SB_54839| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1409

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 44/168 (26%), Positives = 61/168 (36%), Gaps = 12/168 (7%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C       +CTC+AG  G  C   V+ C   PC       ++   GYS
Sbjct: 815  ECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSENPCKNGGVCKNE-HGGYS 873

Query: 1573 CACEPGY--TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            CAC+ G+          E  K  C  G    +  G  +C    G+    N E     C +
Sbjct: 874  CACKAGFMGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACKAGFTGK-NCEQDVNECSK 932

Query: 1631 NHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            N  K +G  +       C C  AG    +CE    +C   P   G  C
Sbjct: 933  NPCKNDGVCKNEHGGYSCAC-KAGFTGKNCEQDMNECSKNPCQNGGVC 979



 Score = 51.6 bits (118), Expect = 9e-06
 Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 16/195 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C       +CTC+AG  G  C   V+ C   PC       ++   GYS
Sbjct: 1043 ECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTCEQDVNECSKNPCKNGGVCKNE-HGGYS 1101

Query: 1573 CACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            CAC+  +T         E  K  C  G    +  G  +C    G+     +++    C +
Sbjct: 1102 CACKAEFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVN-ECSK 1160

Query: 1631 NHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT- 1685
            N  K  G  +       C C  AG    +CE    +C   P   G  C      Y+ V  
Sbjct: 1161 NPCKNGGVCKNEHGGYSCTC-KAGFTGKNCEQDVNECSTNPCQNGGVCKNEHGGYSCVCK 1219

Query: 1686 ---PNSGCEVVYDGC 1697
                   CE   D C
Sbjct: 1220 AGFTGKNCEQDVDEC 1234



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 16/143 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C       +CTC+AG  G  C   V+ C   PC       ++   GYS
Sbjct: 1157 ECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSTNPCQNGGVCKNE-HGGYS 1215

Query: 1573 CACEPGYTLTTSGCIESGKEECPG--GWWGGSAC----GPCACDVTRGY-HPHCNKENGK 1625
            C C+ G+  T   C E   +EC G      G  C    G  +C    GY   +C ++  +
Sbjct: 1216 CVCKAGF--TGKNC-EQDVDECAGVNPCHHGGVCSNSHGGYSCKCASGYTGKNCEQDKNE 1272

Query: 1626 CHCKE--NHYKPEGTAECLPCQC 1646
            C      N+ K   T     C C
Sbjct: 1273 CKVNPCLNNGKCINTPGSYKCNC 1295



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 46/186 (24%), Positives = 68/186 (36%), Gaps = 11/186 (5%)

Query: 1498 LNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL 1554
            LNRP V      G      C    C     C     + +CTC++G  G  C   V+ C  
Sbjct: 644  LNRPPVCHLRYCGNAEFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSK 703

Query: 1555 GPCGAARCVPDQTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVT 1612
             PC       ++   GYSCAC+ G+T         E  +  C  G    +  G  +C   
Sbjct: 704  NPCKNGGVCKNEHG-GYSCACKAGFTGKNCEQDVNECSENPCKNGGVCKNEHGGYSCACK 762

Query: 1613 RGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAA----TGQCHCRPG 1668
             G+    N E     C +N  +  G A+       A   ++S  ++A      +C+  P 
Sbjct: 763  AGFTGK-NCEQDVNECSKNPCQNGGVAKTNMADTLALAKQDSRAKSANKVHVNECNKNPC 821

Query: 1669 VIGRAC 1674
              G  C
Sbjct: 822  QNGGVC 827



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 12/168 (7%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C       +C C+AG  G  C   ++ C   PC       ++   GYS
Sbjct: 929  ECSKNPCKNDGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNKHG-GYS 987

Query: 1573 CACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            CAC+ G+T         E  K  C  G    +  G  +C   +      N E     C +
Sbjct: 988  CACKAGFTGKNCEQDVNECSKYPCQNGGVCKNEHGGYSC-ACKAEFTGKNCEQDVNECSK 1046

Query: 1631 NHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            N  K  G  +       C C  AG    +CE    +C   P   G  C
Sbjct: 1047 NPCKNGGVCKNEHGGYSCTC-KAGFTGKTCEQDVNECSKNPCKNGGVC 1093



 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 17/32 (53%), Positives = 20/32 (62%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSS PC NG  C ++   Y C CK G TGK+C
Sbjct: 663  CSSKPCKNGGTCREVNGAYSCTCKSGFTGKNC 694



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 961  CEQDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNC 999



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 18/46 (39%), Positives = 23/46 (50%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355
            C +  + CS  PC NG  C +    Y C CK G TGK+C  +   P
Sbjct: 313  CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQAPSKP 358



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 41/172 (23%), Positives = 61/172 (35%), Gaps = 12/172 (6%)

Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568
            Q   +C  + C     C       +C C+AG  G  C   V+ C   PC       ++  
Sbjct: 963  QDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSKYPCQNGGVCKNE-H 1021

Query: 1569 KGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
             GYSCAC+  +T         E  K  C  G    +  G  +C    G+     +++   
Sbjct: 1022 GGYSCACKAEFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTCEQDVN- 1080

Query: 1627 HCKENHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
             C +N  K  G  +       C C A  +   +CE    +C   P   G  C
Sbjct: 1081 ECSKNPCKNGGVCKNEHGGYSCACKAEFT-GKNCEQDVNECSKNPCKNGGVC 1131



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C ++ C     C       +C C+AG  G  C   V+ C + PC       ++   GYS
Sbjct: 464  ECSINPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNE-HGGYS 522

Query: 1573 CACEPGYT 1580
            CAC+ G+T
Sbjct: 523  CACKAGFT 530



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 885  CEQDVNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKNC 923



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 1151 CEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNC 1189



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS+ PC NG  C +    Y C CK G TGK+C
Sbjct: 1189 CEQDVNECSTNPCQNGGVCKNEHGGYSCVCKAGFTGKNC 1227



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 694  CEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNC 732



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 732  CEQDVNECSENPCKNGGVCKNEHGGYSCACKAGFTGKNC 770



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/39 (43%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK C
Sbjct: 1037 CEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTC 1075



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 36   CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 74



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 496  CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 534



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C       +C C+AG  G  C   V+ C + PC       ++   GYS
Sbjct: 281  ECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNEHG-GYS 339

Query: 1573 CACEPGYT 1580
            CAC+ G+T
Sbjct: 340  CACKAGFT 347



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 17/39 (43%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK C
Sbjct: 1113 CEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKIC 1151



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 16/34 (47%), Positives = 19/34 (55%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 280  NECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNC 313



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G  GK+C
Sbjct: 847  CEQDVNECSENPCKNGGVCKNEHGGYSCACKAGFMGKNC 885



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 16/34 (47%), Positives = 19/34 (55%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 3    NECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNC 36



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C       +C C+ G  G  C   V+ C + PC       ++   GYS
Sbjct: 4    ECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHG-GYS 62

Query: 1573 CACEPGYT 1580
            CAC+ G+T
Sbjct: 63   CACKAGFT 70



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 15/34 (44%), Positives = 19/34 (55%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C+  PC NG  C +    Y C CK G TGK+C
Sbjct: 814  NECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNC 847



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC N   C +    Y C CK G TGK+C
Sbjct: 923  CEQDVNECSKNPCKNDGVCKNEHGGYSCACKAGFTGKNC 961



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK   TGK+C
Sbjct: 999  CEQDVNECSKYPCQNGGVCKNEHGGYSCACKAEFTGKNC 1037



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 16/34 (47%), Positives = 19/34 (55%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 463  NECSINPCKNGGVCKNEHGGYSCACKAGFTGKNC 496



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK   TGK+C
Sbjct: 1075 CEQDVNECSKNPCKNGGVCKNEHGGYSCACKAEFTGKNC 1113



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    C+   PC++G  CS+    Y C C  G+TGK+C
Sbjct: 1227 CEQDVDECAGVNPCHHGGVCSNSHGGYSCKCASGYTGKNC 1266



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 15/47 (31%), Positives = 24/47 (51%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A   T   C + ++ C   PC N  +C +   +Y C+C + +TGK C
Sbjct: 1258 ASGYTGKNCEQDKNECKVNPCLNNGKCINTPGSYKCNCIDEYTGKHC 1304



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 10/69 (14%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C  GFTG NCE  + +  C V+     C++G  C     GG     C+  A +T  
Sbjct: 483  YSCACKAGFTGKNCEQDVNE--CSVNP----CKNGGVC-KNEHGG---YSCACKAGFTGK 532

Query: 1102 VCELRARSF 1110
             CE   RS+
Sbjct: 533  NCEQECRSY 541



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 5/57 (8%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095
            ++C C  GFTG NCE  + + S     +G +C++   G  CV +   G   + C  D
Sbjct: 1176 YSCTCKAGFTGKNCEQDVNECSTNPCQNGGVCKNEHGGYSCVCK--AGFTGKNCEQD 1230



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 7/63 (11%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSIDAAY 1098
            ++C C  GFTG NCE  + + S     +G +C++   G  C  +   G   + C  + AY
Sbjct: 23   YSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACK--AGFTGKNC--EQAY 78

Query: 1099 TTA 1101
            T A
Sbjct: 79   TRA 81



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 11/71 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C  GFTG NCE  + +  C V+     C++G  C     GG     C+  A +T  
Sbjct: 300  YSCACKAGFTGKNCEQDVNE--CSVNP----CKNGGVC-KNEHGG---YSCACKAGFTGK 349

Query: 1102 VCELRARSFPV 1112
             CE +A S P+
Sbjct: 350  NCE-QAPSKPL 359



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 5/58 (8%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095
            +++C C  GFTG NCE  + + S     +G +C++   G  C  +   G   + C  D
Sbjct: 680  AYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACK--AGFTGKNCEQD 735



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 5/57 (8%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095
            ++C C  GFTG NCE  + + S     +G +C++   G  C  +   G + + C  D
Sbjct: 834  YSCTCKAGFTGKNCEQDVNECSENPCKNGGVCKNEHGGYSCACK--AGFMGKNCEQD 888



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C  GFTG NCE  + + S     +G +C++       + GG     C+  A +T  
Sbjct: 948  YSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKN-------KHGG---YSCACKAGFTGK 997

Query: 1102 VCE 1104
             CE
Sbjct: 998  NCE 1000



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 3/46 (6%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARRE 1084
            ++C C  GFTG NCE  + + S     +G +C++   G  C  + E
Sbjct: 986  YSCACKAGFTGKNCEQDVNECSKYPCQNGGVCKNEHGGYSCACKAE 1031



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 5/57 (8%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095
            ++C C  GFTG NCE  + + S     +G +C++   G  C  +   G   + C  D
Sbjct: 719  YSCACKAGFTGKNCEQDVNECSENPCKNGGVCKNEHGGYSCACK--AGFTGKNCEQD 773



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C   FTG NCE  + + S     +G +C++         GG     C+  A +T  
Sbjct: 1100 YSCACKAEFTGKNCEQDVNECSKNPCKNGGVCKN-------EHGG---YSCTCKAGFTGK 1149

Query: 1102 VCE 1104
            +CE
Sbjct: 1150 ICE 1152



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 3/46 (6%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARRE 1084
            ++C C  GFTG  CE  + + S     +G +C++   G  C  + E
Sbjct: 1062 YSCTCKAGFTGKTCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAE 1107



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 16/57 (28%), Positives = 26/57 (45%), Gaps = 5/57 (8%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARREGGILCQGCSID 1095
            ++C C  GF G NCE  + + S     +G +C++   G  C  +   G   + C  D
Sbjct: 872  YSCACKAGFMGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACK--AGFTGKNCEQD 926



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 5/57 (8%)

Query: 1042 FTCQCPEGFTGVNCETILTKAS---CEVDGDGSICRSGSQCVARREGGILCQGCSID 1095
            ++C C  GFTG NCE  + + S   C+ DG       G  C  +   G   + C  D
Sbjct: 910  YSCACKAGFTGKNCEQDVNECSKNPCKNDGVCKNEHGGYSCACK--AGFTGKNCEQD 964



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C   FTG NCE  + + S     +G +C++         GG     C+  A +T  
Sbjct: 1024 YSCACKAEFTGKNCEQDVNECSKNPCKNGGVCKN-------EHGG---YSCTCKAGFTGK 1073

Query: 1102 VCE 1104
             CE
Sbjct: 1074 TCE 1076



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C+C  G+TG NCE    K  C+V+     C +  +C+    G   C  C ID  YT  
Sbjct: 1253 YSCKCASGYTGKNCEQ--DKNECKVNP----CLNNGKCI-NTPGSYKC-NC-ID-EYTGK 1302

Query: 1102 VCE 1104
             CE
Sbjct: 1303 HCE 1305


>SB_16910| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1552

 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 56/201 (27%), Positives = 69/201 (34%), Gaps = 31/201 (15%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPC-GAARCVPDQTPKGY 1571
            +C+ S C   + CV   D   C C+AG  G  C      C   PC  +A C+ D+    Y
Sbjct: 669  ECLSSPCKNGATCVDRVDGFKCVCDAGYQGSLCQVDRDDCASSPCENSATCI-DRV-DDY 726

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631
             C C PGY  T   C +    +C  G       G    D   GY   C  E     C+  
Sbjct: 727  ECRCAPGY--TGVNC-DHNINDC--GRLNPCQNGGSCIDKLNGYVCSCRPEFTGVECE-- 779

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYAEVTPNSG 1689
               P       PC      + N +C    G   C C  G  G  C+A  N   E  P   
Sbjct: 780  --SPVNKCSSNPC------TNNGTCIQGLGIFMCSCPAGFTGPRCEADINE-CESDPCLN 830

Query: 1690 CEVVYDG-------CPRSFAG 1703
                 DG       CP  F G
Sbjct: 831  SGTCVDGVASFQCKCPVGFTG 851



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 17/39 (43%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C++ PC NG +C DL   Y C+C EG  GK+C
Sbjct: 470  CDQNTNECAARPCINGRKCIDLIGDYACECLEGWQGKNC 508



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 42/164 (25%), Positives = 56/164 (34%), Gaps = 14/164 (8%)

Query: 1511 CQ-SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC-ELGPCGAARCVPD 1565
            CQ  R DC  S C   + C+   D   C C  G  G  C   ++ C  L PC       D
Sbjct: 701  CQVDRDDCASSPCENSATCIDRVDDYECRCAPGYTGVNCDHNINDCGRLNPCQNGGSCID 760

Query: 1566 QTPKGYSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKE 1622
            +   GY C+C P +T     S   +     C          G   C    G+  P C  +
Sbjct: 761  KL-NGYVCSCRPEFTGVECESPVNKCSSNPCTNNGTCIQGLGIFMCSCPAGFTGPRCEAD 819

Query: 1623 NGKCH---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663
              +C    C  +    +G A    C+C   G     CE     C
Sbjct: 820  INECESDPCLNSGTCVDGVAS-FQCKC-PVGFTGKRCETKLNHC 861



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 21/209 (10%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C+++ + C+  +C   + C+   D + C CE+G VG  C   V+ C   PC       D+
Sbjct: 854  CETKLNHCIGHVCANGATCMNGKDKAVCICESGFVGTHCDVNVNECNSMPCQHGGTCIDE 913

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECP-GGWWGGSACGPCACDVTRGYHPHC-NKENG 1624
                + C C  G   T     E   + C     + G++          G H  C N + G
Sbjct: 914  V-NNFRCLCPTG---TRGHFCEQVIDSCKIAVSFNGTSATKIVDTGVCGAHGTCINIQGG 969

Query: 1625 --KCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRACDACANAY 1681
              +C C E +       +   C  +  G+  +  +  +  QC CR G  G  C   A + 
Sbjct: 970  DFRCACDEGYTGNHCHIDIDDCIGHECGNGATCVDGISSYQCICRDGWEGPFCKTMA-SQ 1028

Query: 1682 AEVTP--NSG-CEVVYDG----CPRSFAG 1703
             E  P  N G C+ + D     CP  ++G
Sbjct: 1029 CERNPCQNGGTCQDLDDTFECVCPEGYSG 1057



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    S+C   PC NG  C DL DT+ C C EG++G+ C
Sbjct: 1022 CKTMASQCERNPCQNGGTCQDLDDTFECVCPEGYSGRTC 1060



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 18/39 (46%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C   R  C+S+PC N A C D  D Y C C  G+TG +C
Sbjct: 701  CQVDRDDCASSPCENSATCIDRVDDYECRCAPGYTGVNC 739



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 20/55 (36%), Positives = 29/55 (52%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLR 1371
            C+S+PC  GA C DL   Y C C  G  GK+C  +     R+G + + S N  ++
Sbjct: 1144 CASSPCQAGAHCLDLIGDYTCVCPPGKIGKNCEVNDPNLCRYGDNQLQSHNTTVK 1198



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG-SQCVARREGGILCQGCSID 1095
            V SF C+CP GFTG  CET L      V  +G+ C +G  + V   E G +   C ++
Sbjct: 838  VASFQCKCPVGFTGKRCETKLNHCIGHVCANGATCMNGKDKAVCICESGFVGTHCDVN 895



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 43/182 (23%), Positives = 60/182 (32%), Gaps = 19/182 (10%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAARCVPDQTPK 1569
            C     C  +I     +C + W+  TC         Q    C   PC  A  C+  +T  
Sbjct: 407  CLHNGSCTNTIEGFQCQCTSDWEGKTC---------QLSKDCHSQPCQNAGTCINTET-- 455

Query: 1570 GYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKC 1626
            G+ C C  G+   T      E     C  G       G  AC+   G+   +C++    C
Sbjct: 456  GFQCRCAHGWEGPTCDQNTNECAARPCINGRKCIDLIGDYACECLEGWQGKNCDQNINDC 515

Query: 1627 --HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV 1684
               CK N    +   +   C C   G    +C      C   P +    C A  N Y  V
Sbjct: 516  AGQCKHNGTCIDQLND-YTCHC-PLGYTGKNCGLLVDHCLSNPCLNKGICTAVVNGYQCV 573

Query: 1685 TP 1686
             P
Sbjct: 574  CP 575



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 46/179 (25%), Positives = 61/179 (34%), Gaps = 23/179 (12%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQ 1566
            CQ   DC    C     C+ +     C C  G  GP C    + C   PC    +C+   
Sbjct: 433  CQLSKDCHSQPCQNAGTCINTETGFQCRCAHGWEGPTCDQNTNECAARPCINGRKCI--D 490

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN-KENGK 1625
                Y+C C  G+      C +    +C G       C     D    Y  HC     GK
Sbjct: 491  LIGDYACECLEGW--QGKNC-DQNINDCAGQCKHNGTC----IDQLNDYTCHCPLGYTGK 543

Query: 1626 -C-----HCKENHYKPEG--TAECLPCQCYA-AGSENSSCEAATGQCHCRPGVIGRACD 1675
             C     HC  N    +G  TA     QC    G   ++C+    +C+  P V G   D
Sbjct: 544  NCGLLVDHCLSNPCLNKGICTAVVNGYQCVCPIGFHGNNCQYKDNECYPNPCVHGSCRD 602



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 16/39 (41%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    C++ PCYNGA C D     +C C +G +G DC
Sbjct: 1099 CDKNIDDCANNPCYNGATCVDGVGFRLCACAKGFSGPDC 1137



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 39/141 (27%), Positives = 56/141 (39%), Gaps = 17/141 (12%)

Query: 1552 CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV 1611
            C   PC       +  P  + C C PGYT     C E+  + C       +  G C  + 
Sbjct: 363  CRHLPCQNGGTCFNVGPDQHRCQCHPGYT--GINC-ETRVDSCASNPCLHN--GSCT-NT 416

Query: 1612 TRGYHPHCNKE-NGK-CHC-KENHYKP-EGTAECL------PCQCYAAGSENSSCEAATG 1661
              G+   C  +  GK C   K+ H +P +    C+       C+C A G E  +C+  T 
Sbjct: 417  IEGFQCQCTSDWEGKTCQLSKDCHSQPCQNAGTCINTETGFQCRC-AHGWEGPTCDQNTN 475

Query: 1662 QCHCRPGVIGRACDACANAYA 1682
            +C  RP + GR C      YA
Sbjct: 476  ECAARPCINGRKCIDLIGDYA 496



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 43/171 (25%), Positives = 56/171 (32%), Gaps = 15/171 (8%)

Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568
            Q+  DC    C     C+   +  TC C  G  G  C   V  C   PC   + +     
Sbjct: 510  QNINDCA-GQCKHNGTCIDQLNDYTCHCPLGYTGKNCGLLVDHCLSNPC-LNKGICTAVV 567

Query: 1569 KGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHC 1628
             GY C C  G+    + C     E  P     GS    C  D+   Y   C+      +C
Sbjct: 568  NGYQCVCPIGFH--GNNCQYKDNECYPNPCVHGS----CR-DLIGDYKCVCSDGYSGRNC 620

Query: 1629 KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
                   +G   C P  C   G+          QC C PG  G  C+   N
Sbjct: 621  SVPSV--DGNNACNPDPCLH-GAACIFLSDGGSQCQCLPGYTGAFCETNIN 668



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 18/43 (41%), Positives = 22/43 (51%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T A C    + C S+PC NGA C D  D + C C  G+ G  C
Sbjct: 659  TGAFCETNINECLSSPCKNGATCVDRVDGFKCVCDAGYQGSLC 701



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C  K + C   PC +G+ C DL   Y C C +G++G++C+
Sbjct: 583  CQYKDNECYPNPCVHGS-CRDLIGDYKCVCSDGYSGRNCS 621



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 6/67 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGA-ARCVPDQTPKGY 1571
            DC  + C   + CV       C C  G  GP C   +  C   PC A A C+       Y
Sbjct: 1105 DCANNPCYNGATCVDGVGFRLCACAKGFSGPDCRIDIDECASSPCQAGAHCL--DLIGDY 1162

Query: 1572 SCACEPG 1578
            +C C PG
Sbjct: 1163 TCVCPPG 1169



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 10/62 (16%)

Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103
            CQC  G+TG  CET + +         S C++G+ CV R +G      C  DA Y  ++C
Sbjct: 652  CQCLPGYTGAFCETNINECL------SSPCKNGATCVDRVDG----FKCVCDAGYQGSLC 701

Query: 1104 EL 1105
            ++
Sbjct: 702  QV 703



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 3/55 (5%)

Query: 1297 LNSYVAD---NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            LN YV       T   C    ++CSS PC N   C      ++C C  G TG  C
Sbjct: 762  LNGYVCSCRPEFTGVECESPVNKCSSNPCTNNGTCIQGLGIFMCSCPAGFTGPRC 816



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 1/54 (1%)

Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            D     A   T   C    + C    PC NG  C D  + Y+C C+   TG +C
Sbjct: 725  DYECRCAPGYTGVNCDHNINDCGRLNPCQNGGSCIDKLNGYVCSCRPEFTGVEC 778



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 15/39 (38%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC N   C D   ++ C C  G TGK C
Sbjct: 816  CEADINECESDPCLNSGTCVDGVASFQCKCPVGFTGKRC 854



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 9/66 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  + C+C  G+TGVNC+  +    C   G  + C++G  C+ +  G +    CS    +
Sbjct: 723  VDDYECRCAPGYTGVNCDHNIN--DC---GRLNPCQNGGSCIDKLNGYV----CSCRPEF 773

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 774  TGVECE 779



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 37/192 (19%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC---GAARCVPDQ--- 1566
            DC+   C   + CV    S  C C  G  GP C    S CE  PC   G  + + D    
Sbjct: 990  DCIGHECGNGATCVDGISSYQCICRDGWEGPFCKTMASQCERNPCQNGGTCQDLDDTFEC 1049

Query: 1567 -TPKGYS---CACEPGYTLT-----TSGCIESGKEE----CPGGWWGGSACGPCACDVTR 1613
              P+GYS   C  + G   +      + C++   E+    C  GW  G  C     D   
Sbjct: 1050 VCPEGYSGRTCQLDFGQCYSKPCKNNATCVDQVGEQFVCLCRNGW-EGFYCDKNIDDCAN 1108

Query: 1614 G--YH-PHCNKENG--KCHCKENHYKPE---GTAECLPCQCYAAGSENSSCEAATGQ--C 1663
               Y+   C    G   C C +    P+      EC    C A     + C    G   C
Sbjct: 1109 NPCYNGATCVDGVGFRLCACAKGFSGPDCRIDIDECASSPCQAG----AHCLDLIGDYTC 1164

Query: 1664 HCRPGVIGRACD 1675
             C PG IG+ C+
Sbjct: 1165 VCPPGKIGKNCE 1176



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 5/66 (7%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  + C C +G++G NC       +   + D   C  G+ C+   +GG  CQ C     Y
Sbjct: 604  IGDYKCVCSDGYSGRNCSVPSVDGNNACNPDP--CLHGAACIFLSDGGSQCQ-CL--PGY 658

Query: 1099 TTAVCE 1104
            T A CE
Sbjct: 659  TGAFCE 664



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 10/65 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            F C CP GFTG  CE  + +  CE D     C +   CV     G+    C     +T  
Sbjct: 803  FMCSCPAGFTGPRCEADINE--CESDP----CLNSGTCV----DGVASFQCKCPVGFTGK 852

Query: 1102 VCELR 1106
             CE +
Sbjct: 853  RCETK 857



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 14/39 (35%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  K + C    C NGA C +  D  +C C+ G  G  C
Sbjct: 854  CETKLNHCIGHVCANGATCMNGKDKAVCICESGFVGTHC 892



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 1/33 (3%)

Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348
            C   PC NG  C ++  D + C C  G+TG +C
Sbjct: 363  CRHLPCQNGGTCFNVGPDQHRCQCHPGYTGINC 395



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C+    +NG  C D  + Y C C  G+TGK+C
Sbjct: 508  CDQNINDCAGQCKHNGT-CIDQLNDYTCHCPLGYTGKNC 545



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 2/67 (2%)

Query: 1283 GCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWD-TYICDCKE 1341
            G   D   D+K +  + Y   N ++    +  + C+  PC +GA C  L D    C C  
Sbjct: 598  GSCRDLIGDYKCVCSDGYSGRNCSVPSV-DGNNACNPDPCLHGAACIFLSDGGSQCQCLP 656

Query: 1342 GHTGKDC 1348
            G+TG  C
Sbjct: 657  GYTGAFC 663



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 11/39 (28%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C+S PC +   C++  + + C C     GK C
Sbjct: 395  CETRVDSCASNPCLHNGSCTNTIEGFQCQCTSDWEGKTC 433



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S PC +G  C D  + + C C  G  G  C
Sbjct: 892  CDVNVNECNSMPCQHGGTCIDEVNNFRCLCPTGTRGHFC 930



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 1044 CQCPEGFTGVNCETILTKAS---CEVDGDGSICRSGSQCVARRE-GGILCQ 1090
            CQC  G+TG+NCET +   +   C  +G  +    G QC    +  G  CQ
Sbjct: 384  CQCHPGYTGINCETRVDSCASNPCLHNGSCTNTIEGFQCQCTSDWEGKTCQ 434



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSD-LWDTYICDCKEGHTGKDC 1348
            C     +C S PC N A C D + + ++C C+ G  G  C
Sbjct: 1060 CQLDFGQCYSKPCKNNATCVDQVGEQFVCLCRNGWEGFYC 1099



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCV 1080
            +  +TC CP G+TG NC  ++         +  IC    +G QCV
Sbjct: 529  LNDYTCHCPLGYTGKNCGLLVDHCLSNPCLNKGICTAVVNGYQCV 573



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 3/44 (6%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG---SQCVAR 1082
            F C C EG+TG +C   +        G+G+ C  G    QC+ R
Sbjct: 971  FRCACDEGYTGNHCHIDIDDCIGHECGNGATCVDGISSYQCICR 1014



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 13/32 (40%), Positives = 16/32 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    C NGA C D   +Y C C++G  G  C
Sbjct: 991  CIGHECGNGATCVDGISSYQCICRDGWEGPFC 1022


>SB_3456| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 462

 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 20/39 (51%), Positives = 26/39 (66%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            E+ S+C  +PC NG ECS+  + Y C C+EG  GKDC D
Sbjct: 114  EEPSKCHPSPCRNGGECSETEEGYTCLCREGFRGKDCED 152



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 47/190 (24%), Positives = 66/190 (34%), Gaps = 15/190 (7%)

Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPCGAARCVPDQ 1566
            D C+  + C  S C    +C  + +  TC C  G  G  C  ++ C+  PC  +    +Q
Sbjct: 111  DNCEEPSKCHPSPCRNGGECSETEEGYTCLCREGFRGKDCEDLNQCDPNPCKNSGTCFEQ 170

Query: 1567 TPKGYSCACEPGYTLTTSGCI-ESGKEEC-PGGWWGGSACG-PCACDVTRGYHPH-CN-- 1620
                + C C   Y   T   + E     C  GG    +A G  C C    GY  + C   
Sbjct: 171  N-GDFVCNCPKMYRGKTCEVVSECTAARCVNGGSCHDTATGFKCKCPF--GYFGNRCEVY 227

Query: 1621 -KENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
             K     +     Y    TA C P  C   G    S       C C  G  G+ C+  + 
Sbjct: 228  YKTKTGLYSLSATYVSTVTA-CQPNPCLNGGL--CSRFGTQHSCQCARGYSGKHCEEHSP 284

Query: 1680 AYAEVTPNSG 1689
                +  N G
Sbjct: 285  CGTSICMNGG 294



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C   PC NG  CS     + C C  G++GK C +
Sbjct: 248  CQPNPCLNGGLCSRFGTQHSCQCARGYSGKHCEE 281



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            S C++A C NG  C D    + C C  G+ G  C
Sbjct: 191  SECTAARCVNGGSCHDTATGFKCKCPFGYFGNRC 224



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 11/37 (29%), Positives = 19/37 (51%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E  ++C   PC N   C +    ++C+C + + GK C
Sbjct: 151  EDLNQCDPNPCKNSGTCFEQNGDFVCNCPKMYRGKTC 187



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 8/75 (10%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARR-EGGILCQGCSIDAAY 1098
            T  +CQC  G++G +CE     + C      SIC +G  CV            C     Y
Sbjct: 264  TQHSCQCARGYSGKHCE---EHSPCGT----SICMNGGTCVDNTFTNSRYGFACVCPRGY 316

Query: 1099 TTAVCELRARSFPVS 1113
            T  +CE   +   VS
Sbjct: 317  TGILCEKHRKRNKVS 331


>SB_20264| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 480

 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 52/201 (25%), Positives = 74/201 (36%), Gaps = 26/201 (12%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  S C     CV   +  +CTC AG  G  C   +  C   PC       D    G++
Sbjct: 142  ECKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCETDIDECAGNPCANGGTCKDGI-NGFT 200

Query: 1573 CACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPCACDVTRGYHPHCNKENGKCH---C 1628
            C C  GY  +T  C E   +EC  G    G+ C     + T    P  N  N + +   C
Sbjct: 201  CECAVGYNGST--C-EIDIDECASGPCQNGATCNDGVNNYTCSCIPGFNGTNCETNIDEC 257

Query: 1629 KENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQC---------HCRPGVIGRACD 1675
                 +  GT         C C   G   ++CE    +C          C+ G+ G  C+
Sbjct: 258  ASGPCQNGGTCNDGVNNYTCLC-IPGFNGTNCETNIDECIGNPCANGGTCKDGINGFTCE 316

Query: 1676 ACANAYAEVTPNSGCEVVYDG 1696
             C   Y+  T   GC++   G
Sbjct: 317  -CPVGYSGSTCEIGCDLAAIG 336



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DGMLSF 1366
            C S+PC NG  C D  + Y C C  G TGK+C     +  G P   GG   DG+  F
Sbjct: 143  CKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCETDIDECAGNPCANGGTCKDGINGF 199



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC NGA C+D  + Y C C  G  G +C
Sbjct: 212  CEIDIDECASGPCQNGATCNDGVNNYTCSCIPGFNGTNC 250



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            NGT   C      C+S PC NG  C+D  + Y C C  G  G +C
Sbjct: 246  NGT--NCETNIDECASGPCQNGGTCNDGVNNYTCLCIPGFNGTNC 288



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 2/45 (4%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            NGT   C      C   PC NG  C D  + + C+C  G++G  C
Sbjct: 284  NGT--NCETNIDECIGNPCANGGTCKDGINGFTCECPVGYSGSTC 326



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+  PC NG  C D  + + C+C  G+ G  C
Sbjct: 174  CETDIDECAGNPCANGGTCKDGINGFTCECAVGYNGSTC 212



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  ++C C  GFTG NCET + + +     +G  C+ G         G  C+ C++   Y
Sbjct: 158  INRYSCTCVAGFTGKNCETDIDECAGNPCANGGTCKDGI-------NGFTCE-CAV--GY 207

Query: 1099 TTAVCEL 1105
              + CE+
Sbjct: 208  NGSTCEI 214



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V ++TC C  GF G NCET + +        G+ C +G  C    + GI    C     Y
Sbjct: 272  VNNYTCLCIPGFNGTNCETNIDECI------GNPCANGGTC----KDGINGFTCECPVGY 321

Query: 1099 TTAVCEL 1105
            + + CE+
Sbjct: 322  SGSTCEI 328



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 14/38 (36%), Positives = 20/38 (52%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            V ++TC C  GF G NCET + + +     +G  C  G
Sbjct: 234  VNNYTCSCIPGFNGTNCETNIDECASGPCQNGGTCNDG 271



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 11/38 (28%), Positives = 19/38 (50%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            +  FTC+C  G+ G  CE  + + +     +G+ C  G
Sbjct: 196  INGFTCECAVGYNGSTCEIDIDECASGPCQNGATCNDG 233


>SB_2152| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1603

 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 48/190 (25%), Positives = 68/190 (35%), Gaps = 19/190 (10%)

Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV----SACELGPC-GAARC 1562
            D C+   D C  + C  YS C+   ++ TC C     G  C     + C+  PC     C
Sbjct: 9    DYCEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLCDPNPCQNGGVC 68

Query: 1563 VPDQTPKGYSCACEPGYT-LTTSGCIESGKE-ECPGGWW---GGSACGPCACDVTRGYHP 1617
                    Y+CAC  GYT    +G +   +   C  G       +A     C    G++ 
Sbjct: 69   KETFDRNNYTCACPQGYTGWNCNGTLHPCETLNCNNGGTCQKQSNASDDYVCVCVTGFNG 128

Query: 1618 -HCNKENGKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPG--VIG 1671
              C +    C    CK  H K         C C  +G E   C+    +C  +PG  + G
Sbjct: 129  IRCEQNIDDCASLPCK--HGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNG 186

Query: 1672 RACDACANAY 1681
              CD     Y
Sbjct: 187  GTCDNYLGTY 196



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 47/176 (26%), Positives = 64/176 (36%), Gaps = 16/176 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            CQ   D C  + C     CV   +   C+C  G  G +C   +  C    C A +   DQ
Sbjct: 209  CQENIDECDPNPCLNGGTCVDGINGFNCSCFIGFTGERCETNIDDCVSNTCNANQDCVDQ 268

Query: 1567 TPKGYSCACEPGYTLT--TSGCIESGKEEC-PGGWWGGSACG-PCACDVTRGYHPHCNKE 1622
                Y+C C+PGYT +  +   +E     C  GG       G  C C + R    HC  +
Sbjct: 269  V-NNYTCVCKPGYTGSDCSVDILECLSNPCRHGGTCHEGVNGYNCTC-LPRFNGTHCELD 326

Query: 1623 NGKCHCKENHYKPEGT----AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
                 C  +     GT         C C  A  +   CE  +  CH  P   G +C
Sbjct: 327  TVN-DCNSSPCLNNGTCVDDVGFFNCTCPKA-FDGVRCENKSDSCHPNPCKHGASC 380



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 39/177 (22%), Positives = 55/177 (31%), Gaps = 14/177 (7%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC+ + C     CV   ++ TC C+ G  G  C   +  C   PC     C   +   GY
Sbjct: 253  DCVSNTCNANQDCVDQVNNYTCVCKPGYTGSDCSVDILECLSNPCRHGGTC--HEGVNGY 310

Query: 1572 SCACEPGYTLT---TSGCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCH 1627
            +C C P +  T        +     C          G   C   + +    C  ++  CH
Sbjct: 311  NCTCLPRFNGTHCELDTVNDCNSSPCLNNGTCVDDVGFFNCTCPKAFDGVRCENKSDSCH 370

Query: 1628 ---CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
               CK              C C   G    +C+     C   P V    C    N Y
Sbjct: 371  PNPCKHGASCAIVNETDFTCAC-PTGYTGKTCDIDIDDCASAPCVANATCVDLLNNY 426



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 7/54 (12%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDC---ADSTGP-PWRFGG---DGMLSFN 1367
            PC NG  C +   TY C CK G+ GK+C    D   P P   GG   DG+  FN
Sbjct: 182  PCLNGGTCDNYLGTYGCSCKAGYRGKNCQENIDECDPNPCLNGGTCVDGINGFN 235



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 16/44 (36%), Positives = 24/44 (54%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            C      C+SAPC++ + C D  + Y C C    TG+DC+ + G
Sbjct: 11   CEINIDECASAPCHSYSTCLDGVNNYTCLCGPRWTGRDCSTNLG 54



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348
            C  K   C   PC +GA C+ + +T + C C  G+TGK C
Sbjct: 362  CENKSDSCHPNPCKHGASCAIVNETDFTCACPTGYTGKTC 401



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 15/32 (46%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+SAPC   A C DL + Y C C  G+ G  C
Sbjct: 408  CASAPCVANATCVDLLNNYTCKCASGYHGDLC 439



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C      C S  C    +C D  + Y C CK G+TG DC+    +    P R GG
Sbjct: 247  CETNIDDCVSNTCNANQDCVDQVNNYTCVCKPGYTGSDCSVDILECLSNPCRHGG 301



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354
            C   PC NG  C + +D   Y C C +G+TG +C  +  P
Sbjct: 57   CDPNPCQNGGVCKETFDRNNYTCACPQGYTGWNCNGTLHP 96



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 15/39 (38%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E    C   PC NG  C D  + + C C  G TG+ C
Sbjct: 209  CQENIDECDPNPCLNGGTCVDGINGFNCSCFIGFTGERC 247



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 14/105 (13%)

Query: 1002 CVHEPCLNFEEC-LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILT 1060
            C   P  N   C L  +   N+S  +N+ +     +  V  F C CP+ F GV CE    
Sbjct: 312  CTCLPRFNGTHCELDTVNDCNSSPCLNNGTC----VDDVGFFNCTCPKAFDGVRCEN--K 365

Query: 1061 KASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105
              SC  +     C+ G+ C    E       C+    YT   C++
Sbjct: 366  SDSCHPNP----CKHGASCAIVNETDFT---CACPTGYTGKTCDI 403



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 13/37 (35%), Positives = 19/37 (51%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS 1077
            ++TC CP+G+TG NC   L         +G  C+  S
Sbjct: 76   NYTCACPQGYTGWNCNGTLHPCETLNCNNGGTCQKQS 112



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC 1557
            DC  + C   + CV   ++ TC C +G  G  C   ++ CE  PC
Sbjct: 407  DCASAPCVANATCVDLLNNYTCKCASGYHGDLCQFDINECESNPC 451


>SB_13309| Best HMM Match : EGF (HMM E-Value=0)
          Length = 718

 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 56/214 (26%), Positives = 81/214 (37%), Gaps = 35/214 (16%)

Query: 1513 SRADCMLSICPPYSKCVTSWDSST---CTCEAGRVGPQC---VSAC-ELGPCGAARCVPD 1565
            +++ C  + C    KC       +   C C +G  G +C   V+ C    PC     V  
Sbjct: 341  TKSPCSPNPCENGGKCADDLGQDSGYRCVCRSGFSGARCQSDVNECASSNPCKNGG-VCT 399

Query: 1566 QTPKGYSCACEPGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHC 1619
             +P GYSC C  GYT        + C  S    C  G    ++ G  +C    GY   +C
Sbjct: 400  NSPGGYSCKCASGYTGKNCEKDVNECASS--NPCKNGGVCTNSPGGYSCKCASGYTGKNC 457

Query: 1620 NKENGKCHCKENHYKPEGTAECLP----CQCYAAGSENSSCEAATGQC----HCRPGVI- 1670
             K+  +C    N  K  G     P    C+C A+G    +CE    +C     C+ G + 
Sbjct: 458  EKDVNEC-ASSNPCKNGGVCTNSPGGYSCKC-ASGYTGKNCEKDVNECASSNPCKNGGVC 515

Query: 1671 ----GRACDACANAYAEVTPNSGCEVVYDGCPRS 1700
                GR    CA+ Y        CE+  + C  S
Sbjct: 516  ANSPGRYSCECASGYT----GKNCEIDVNECASS 545



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 17/47 (36%), Positives = 25/47 (53%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A   T   C +   +C  +PC NG +C +    Y C+CK G++GK C
Sbjct: 566  ASGYTGKNCEKDEDKCKVSPCQNGGKCINSDGGYSCECKGGYSGKHC 612



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A   T   C +  + C+S+ PC NG  C++    Y C+C  G+TGK+C
Sbjct: 488  ASGYTGKNCEKDVNECASSNPCKNGGVCANSPGRYSCECASGYTGKNC 535



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 38/125 (30%), Positives = 49/125 (39%), Gaps = 16/125 (12%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC-ELGPCGAARCVPDQTPKGYSCACEP 1577
            C     C  S    +C C +G  G  C   V+ C    PC     V   +P GYSC C  
Sbjct: 509  CKNGGVCANSPGRYSCECASGYTGKNCEIDVNECASSNPCKNGG-VCTNSPGGYSCKCAS 567

Query: 1578 GYTLTTSGCIESGKEECP-GGWWGGSAC----GPCACDVTRGYH-PHC-NKENGKCHC-K 1629
            GY  T   C E  +++C       G  C    G  +C+   GY   HC   +     C K
Sbjct: 568  GY--TGKNC-EKDEDKCKVSPCQNGGKCINSDGGYSCECKGGYSGKHCETAKYASLGCFK 624

Query: 1630 ENHYK 1634
            +NH K
Sbjct: 625  DNHKK 629



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 1308 AGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A C    + C+S+ PC NG  C++    Y C C  G+TGK+C
Sbjct: 377  ARCQSDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 418



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A   T   C +  + C+S+ PC NG  C++    Y C C  G+TGK+C
Sbjct: 410  ASGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 457



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A   T   C +  + C+S+ PC NG  C++    Y C C  G+TGK+C
Sbjct: 449  ASGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 496



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 1302 ADNGTLAGCPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A   T   C    + C+S+ PC NG  C++    Y C C  G+TGK+C
Sbjct: 527  ASGYTGKNCEIDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNC 574



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C+C  G+TG NCE    +  C+V    S C++G +C+   +GG  C+ C     Y+  
Sbjct: 561  YSCKCASGYTGKNCEK--DEDKCKV----SPCQNGGKCI-NSDGGYSCE-CK--GGYSGK 610

Query: 1102 VCE 1104
             CE
Sbjct: 611  HCE 613



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSD---LWDTYI 1336
            DF G   D  + H++ D   +++ N      P K S CS  PC NG +C+D       Y 
Sbjct: 313  DFNGDGEDDLLCHRYSDGYKWISYNRY----PTK-SPCSPNPCENGGKCADDLGQDSGYR 367

Query: 1337 CDCKEGHTGKDC 1348
            C C+ G +G  C
Sbjct: 368  CVCRSGFSGARC 379



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 9/63 (14%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C+C  G+TG NCE  + + +       + C++G  C     GG  C+ C+  + YT  
Sbjct: 522  YSCECASGYTGKNCEIDVNECA-----SSNPCKNGGVC-TNSPGGYSCK-CA--SGYTGK 572

Query: 1102 VCE 1104
             CE
Sbjct: 573  NCE 575



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 9/63 (14%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C+C  G+TG NCE  + + +       + C++G  C     GG  C+ C+  + YT  
Sbjct: 405  YSCKCASGYTGKNCEKDVNECA-----SSNPCKNGGVC-TNSPGGYSCK-CA--SGYTGK 455

Query: 1102 VCE 1104
             CE
Sbjct: 456  NCE 458



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 9/64 (14%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C+C  G+TG NCE  + + +       + C++G  C A   G   C+ C+  + YT  
Sbjct: 483  YSCKCASGYTGKNCEKDVNECA-----SSNPCKNGGVC-ANSPGRYSCE-CA--SGYTGK 533

Query: 1102 VCEL 1105
             CE+
Sbjct: 534  NCEI 537


>SB_16967| Best HMM Match : Laminin_EGF (HMM E-Value=0)
          Length = 1706

 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 44/149 (29%), Positives = 64/149 (42%), Gaps = 32/149 (21%)

Query: 1549 VSACELGPCGAARCVPDQTPKGY--SCACEPGYTLTTSGCIESGKEECPGGWWGGSA--- 1603
            V+AC LG      C+   T       C+C+P   +    C     ++C  G WG +    
Sbjct: 393  VNAC-LGITNNGSCLTQATDTEQIGQCSCKPN--VYGRRC-----DQCIPGHWGFTLPPQ 444

Query: 1604 --CGPCACDV--TRGYHPHCNKENGKCHCKEN-------------HYKP-EGTAECLPCQ 1645
              C  C C++  TR    +C++  G+C CK +             H  P +G   C PCQ
Sbjct: 445  GECKACNCNISGTRNATINCDQLTGQCFCKPSIQGVYCDGCRDGFHTFPTQGDGGCAPCQ 504

Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            C   G   S C+ ++G C CR GV G +C
Sbjct: 505  CDLGGGF-SICDKSSGSCTCRKGVEGFSC 532



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 12/83 (14%)

Query: 1607 CACDVTRGYHP-HCNKENGKCHCKE-------NHYKPE----GTAECLPCQCYAAGSENS 1654
            C CD     +P  C    G+C CK        NH  P       + C  C+C  +GS   
Sbjct: 738  CECDPEGSTNPTQCVAYGGQCPCKPGVAGLKCNHCLPGYYALSRSGCKKCECSMSGSITP 797

Query: 1655 SCEAATGQCHCRPGVIGRACDAC 1677
             C+ A G+C C+  V G  CDAC
Sbjct: 798  ICDNADGKCQCKANVEGAKCDAC 820



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 4/49 (8%)

Query: 1635 PEGTAECLPCQCYAAGSENSS--CEAATGQCHCRPGVIGRACDACANAY 1681
            P+G  EC  C C  +G+ N++  C+  TGQC C+P + G  CD C + +
Sbjct: 443  PQG--ECKACNCNISGTRNATINCDQLTGQCFCKPSIQGVYCDGCRDGF 489



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 1620 NKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN-SSCEAATGQCHCRPGVIGRACDACA 1678
            N EN +C         E       C+C   GS N + C A  GQC C+PGV G  C+ C 
Sbjct: 714  NTENPQCRALVFSASTELYNGTKVCECDPEGSTNPTQCVAYGGQCPCKPGVAGLKCNHCL 773

Query: 1679 NAYAEVTPNSGCE 1691
              Y  ++  SGC+
Sbjct: 774  PGYYALS-RSGCK 785



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 20/154 (12%)

Query: 1552 CELGPCGAARCVPDQ-TPKGYSCACEPGYT-LTTSGCIESGKEECPGGW-WGGSACGPCA 1608
            CE  P G+    P Q    G  C C+PG   L  + C+       PG +    S C  C 
Sbjct: 738  CECDPEGSTN--PTQCVAYGGQCPCKPGVAGLKCNHCL-------PGYYALSRSGCKKCE 788

Query: 1609 CDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ--CYAAGSEN-SSCEAATGQCHC 1665
            C ++    P C+  +GKC CK N    EG A+C  C+   +   S N   C+   G  H 
Sbjct: 789  CSMSGSITPICDNADGKCQCKAN---VEG-AKCDACKYGTFHLDSGNPHGCQHCFGYGHA 844

Query: 1666 RPGVIGRACDACANAYAEVTPNSGCEVV-YDGCP 1698
                      A       +T + G  VV Y G P
Sbjct: 845  HNCTSASGFIATNITSNFITGSDGWTVVDYSGIP 878



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 37/135 (27%), Positives = 48/135 (35%), Gaps = 13/135 (9%)

Query: 1555 GPCGAARCVPDQTPKGYSCA-CEPGYTLTT-SGCIESGKEECPGGWWGGSACGPCACDVT 1612
            GP  + RC  +    G  C  CEP +         ++   EC        A   C  + T
Sbjct: 299  GPIMSRRCECEHNTMGTDCEMCEPLFNNRPWMRANQTHGNECQECNCNNHATS-CVYNET 357

Query: 1613 RGYH--PHC--NKENGKC-HCKENHYKPEGTAECLPCQCYAAGSENSSCEAAT-----GQ 1662
             GY     C  N +   C +C   HY+           C    +  S    AT     GQ
Sbjct: 358  LGYGLCKGCQHNTQGDHCQNCTAKHYRDLSKPINHVNACLGITNNGSCLTQATDTEQIGQ 417

Query: 1663 CHCRPGVIGRACDAC 1677
            C C+P V GR CD C
Sbjct: 418  CSCKPNVYGRRCDQC 432



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 30/89 (33%), Positives = 38/89 (42%), Gaps = 13/89 (14%)

Query: 1605 GPCA-CDV-TRGYHPH-C--NKENGKC-HCKENHYKPEGTAECLPCQCYAAG---SENSS 1655
            G C  C + T GY    C  N +  +C  CK  ++       C  C C   G   S  S 
Sbjct: 1022 GVCTDCKIGTHGYRCELCTNNVQGPECVRCKPQYWGLSKDG-CKACDCNLPGTLYSNTSV 1080

Query: 1656 CEAATGQCHCRP--GVIGRACDAC-ANAY 1681
            C+  TGQC C     + G+ CD C  NAY
Sbjct: 1081 CDQTTGQCSCNATLHIGGQLCDRCEENAY 1109


>SB_8425| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1955

 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 5/71 (7%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  + C     CV   +  TCTC+AG  G +C   V  C   PC    C       GY 
Sbjct: 587  DCAKNPCLNNGACVDQVNGYTCTCKAGFAGSRCDRNVDNCYPNPCVNGVC--KNKVNGYE 644

Query: 1573 CACEPGYTLTT 1583
            CAC PGY+ +T
Sbjct: 645  CACNPGYSGST 655



 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 60/237 (25%), Positives = 75/237 (31%), Gaps = 20/237 (8%)

Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS---ACELGPCGAARCVPD 1565
            D C    +C  S C    +C +  D   C C  G  G +C +    C   PC       D
Sbjct: 428  DMCLDIDNCASSPCQNGGRCESLKDDFRCACPGGFTGRRCETEQDECLSDPCYQGSTCID 487

Query: 1566 QTPKGYSCACEPGYTLTTSGCIES--GKEECPGGWWGGSACGPCACDVTRGYHP-HCNKE 1622
            +   GY C C  GY+      I        C  G    +     AC+   GY    C ++
Sbjct: 488  KV-NGYECICAAGYSGPNCDVISGLCSSSRCQNGAKCVAKPPSGACECPEGYGGLFCERK 546

Query: 1623 NGKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
               C    CK N        +   C C   G     CE     C   P +   AC    N
Sbjct: 547  MDFCVSAPCK-NGGLCRSLQDKFQCNC-RPGFSGDRCEIDIDDCAKNPCLNNGACVDQVN 604

Query: 1680 AYAEVT----PNSGCEVVYDGC-PRSFAGGVWWPRTKFGVETITDCPPGSSGRATRT 1731
             Y          S C+   D C P     GV   +   G E    C PG SG    T
Sbjct: 605  GYTCTCKAGFAGSRCDRNVDNCYPNPCVNGVCKNKVN-GYECA--CNPGYSGSTCAT 658



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  K   C SAPC NG  C  L D + C+C+ G +G  C
Sbjct: 543  CERKMDFCVSAPCKNGGLCRSLQDKFQCNCRPGFSGDRC 581



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 15/32 (46%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S+PC NG  C  L D + C C  G TG+ C
Sbjct: 436  CASSPCQNGGRCESLKDDFRCACPGGFTGRRC 467



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  ++  C S PCY G+ C D  + Y C C  G++G +C
Sbjct: 467  CETEQDECLSDPCYQGSTCIDKVNGYECICAAGYSGPNC 505



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 17/51 (33%), Positives = 24/51 (47%)

Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355
            G     P  +  C S  C NG  C DL + + C C  G+ G+ C  ++G P
Sbjct: 1096 GCKESVPVAKGTCVSNSCTNGGTCVDLPNEFKCVCPSGYEGRRCEHASGCP 1146



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 46/171 (26%), Positives = 64/171 (37%), Gaps = 30/171 (17%)

Query: 1538 TCEAGR-VG--PQCVSACELG----PCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESG 1590
            TC  GR  G  PQCV   E      PC A +C    T   ++C+C PGY L + G   + 
Sbjct: 1185 TCNHGRWTGNDPQCVDINECNSASSPC-AQQCT--NTEGSFTCSCNPGYNLGSDGVTCND 1241

Query: 1591 KEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECL---PCQCY 1647
              EC       S  G C+      +  +  K + +C C        G   C     C   
Sbjct: 1242 VNEC-------SLTGICS------HKCYNTKGSFRCECPAGMELAAGGRSCQDKDECAIQ 1288

Query: 1648 AAGSENSSCEA-ATGQCHCRPGV-IGRACDACANAYAEVT--PNSGCEVVY 1694
              G E++         C CR G  +     +CA  +  VT  P  G E ++
Sbjct: 1289 NGGCEHACANGYLRSTCQCRGGYNLESDIRSCAEIHCPVTTPPTGGKETIH 1339



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 40/152 (26%), Positives = 49/152 (32%), Gaps = 14/152 (9%)

Query: 1565 DQTPKGYSCA--CEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620
            D+     SC   C+PGY  +T  + C    + E   G      C PC    T       +
Sbjct: 314  DEAKNFTSCTEKCKPGYYSSTGLARCTICPRGEYASGHMN-KKCAPCPQGTTTVLAAATS 372

Query: 1621 KENGKCHCKENHYKPEGTAECLPCQ--CYAAGSENSSCEAATGQCHCR-PGVIGR-ACDA 1676
            +E     C    Y   G   CLPC    Y       SC    G      PG      C  
Sbjct: 373  REECGMMCAPGTYSSSGVEPCLPCPKGTYQTAIGQMSCSECPGTKSTHGPGADSHDMCLD 432

Query: 1677 CANAYAEVTPNSG-CEVVYD----GCPRSFAG 1703
              N  +    N G CE + D     CP  F G
Sbjct: 433  IDNCASSPCQNGGRCESLKDDFRCACPGGFTG 464



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 11/85 (12%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  + C C  G++G NC+ I     C      S C++G++CVA+   G     C     Y
Sbjct: 489  VNGYECICAAGYSGPNCDVI--SGLC----SSSRCQNGAKCVAKPPSG----ACECPEGY 538

Query: 1099 TTAVCELRARSFPVSSFLTFPGLKR 1123
                CE R   F VS+     GL R
Sbjct: 539  GGLFCE-RKMDFCVSAPCKNGGLCR 562



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 13/32 (40%), Positives = 15/32 (46%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+  PC N   C D  + Y C CK G  G  C
Sbjct: 588  CAKNPCLNNGACVDQVNGYTCTCKAGFAGSRC 619



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/32 (43%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSS+ C NGA+C     +  C+C EG+ G  C
Sbjct: 512  CSSSRCQNGAKCVAKPPSGACECPEGYGGLFC 543



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 10/64 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            F C CP GFTG  CET   +  C  D     C  GS C+ +  G      C   A Y+  
Sbjct: 454  FRCACPGGFTGRRCET--EQDECLSDP----CYQGSTCIDKVNG----YECICAAGYSGP 503

Query: 1102 VCEL 1105
             C++
Sbjct: 504  NCDV 507



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C   PC NG  C +  + Y C C  G++G  CA
Sbjct: 619  CDRNVDNCYPNPCVNGV-CKNKVNGYECACNPGYSGSTCA 657



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 34/150 (22%), Positives = 53/150 (35%), Gaps = 20/150 (13%)

Query: 1513 SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPCGAARCVPDQTPKG 1570
            ++  C+ + C     CV   +   C C +G  G +C   S C          +   T  G
Sbjct: 1104 AKGTCVSNSCTNGGTCVDLPNEFKCVCPSGYEGRRCEHASGCPSPKSPTNGKIVSSTGSG 1163

Query: 1571 Y----SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
            +    +  C  G+ LT  G        C  G W G+   P   D+       CN  +  C
Sbjct: 1164 HGSSVTVTCNAGFKLTGDGV-----RTCNHGRWTGN--DPQCVDIN-----ECNSASSPC 1211

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSC 1656
              +  + +   T  C P   Y  GS+  +C
Sbjct: 1212 AQQCTNTEGSFTCSCNP--GYNLGSDGVTC 1239


>SB_59261| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 5445

 Score = 51.6 bits (118), Expect = 9e-06
 Identities = 19/38 (50%), Positives = 24/38 (63%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            CSS PC NG  C+D+ D Y C C+EG TG++C     P
Sbjct: 1620 CSSTPCRNGGTCNDIVDGYKCTCQEGKTGRNCEFDDSP 1657



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 19/65 (29%), Positives = 30/65 (46%)

Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343
            C+++        D     +   T   C  +++ CSS PC NG  C+     Y C+C  G+
Sbjct: 2590 CMNEAKCTEMIRDFQCECSAEFTGKNCELRKTNCSSNPCQNGGTCNVTDTGYKCECFVGY 2649

Query: 1344 TGKDC 1348
             GK+C
Sbjct: 2650 IGKEC 2654



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 24/73 (32%), Positives = 28/73 (38%), Gaps = 5/73 (6%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPC-GAARCVPDQ 1566
            CQ  A C  + C     C    D   CTC+ G+ G  C    S C   PC     C    
Sbjct: 1614 CQVMAPCSSTPCRNGGTCNDIVDGYKCTCQEGKTGRNCEFDDSPCASSPCKNGGNCTKVD 1673

Query: 1567 TPKGYSCACEPGY 1579
              K Y CAC  G+
Sbjct: 1674 DVK-YECACALGF 1685



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 7/85 (8%)

Query: 1502 TVRENVRDG-CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV--SACELGPCG 1558
            ++ + +RD  C +   C LS C     C+      TCTC +G  G  C     C L    
Sbjct: 4386 SIVDKLRDQICIASHPCALSPCKNGGFCLGDLSGYTCTCASGWTGVNCEIRDFCALASVN 4445

Query: 1559 AARC----VPDQTPKGYSCACEPGY 1579
               C    V   TP  Y+C C  G+
Sbjct: 4446 GPACFNGGVCTNTPTSYTCTCARGF 4470



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 1/44 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDCADST 1352
            C    S C+S+PC NG  C+ + D  Y C C  G  G +C D+T
Sbjct: 1651 CEFDDSPCASSPCKNGGNCTKVDDVKYECACALGFRGINCEDAT 1694



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 16/44 (36%), Positives = 21/44 (47%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            C +  S C SAPC NGA C+    ++ C C   + G  C    G
Sbjct: 1690 CEDATSTCDSAPCQNGATCTPTNTSFQCACLVEYAGNTCEKLCG 1733



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDC-KEGHTGKDCAD 1350
            E ++ CS APC NG  C++  D + C+C   G TG  C +
Sbjct: 3619 EAKAPCSGAPCKNGGICTENGDLFNCNCTSTGFTGPTCEE 3658



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 14/32 (43%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S+PC NG  CS L   Y+C C +   G  C
Sbjct: 5004 CASSPCKNGGTCSKLSSGYVCKCTKQFNGSRC 5035



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E    C    C N A C +   ++ CDCKEG+TG  C
Sbjct: 4781 CGEDVDECYHMLCKNDALCINTLGSFKCDCKEGYTGLTC 4819



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 3/35 (8%)

Query: 1317 CSSAPCYNGAECSD---LWDTYICDCKEGHTGKDC 1348
            CSS+PC N   C++   +   Y C C  G TGKDC
Sbjct: 492  CSSSPCNNNGNCTNKVAIPGDYSCACHTGFTGKDC 526



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C S PC N A+C+++   + C+C    TGK+C
Sbjct: 2585 CESNPCMNEAKCTEMIRDFQCECSAEFTGKNC 2616



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 1288 FYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKD 1347
            F++++  ++L +Y   +     C + R  C   PC+NGA+C +    + C C  G  G+ 
Sbjct: 5387 FHVEYSGLNLIAYAIRDRI---CID-RDECIGNPCFNGAKCVNTASGFTCMCAPGFYGQY 5442

Query: 1348 C 1348
            C
Sbjct: 5443 C 5443



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 13/32 (40%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+ +PC NGA C    + Y C C   +TG++C
Sbjct: 753  CALSPCKNGATCFRQNNDYTCKCPITYTGRNC 784



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 13/33 (39%), Positives = 15/33 (45%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            +C+  PC NG  C D      C C   H GK C
Sbjct: 3067 KCTPNPCKNGGTCIDRGYRNYCKCPVSHVGKSC 3099



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 9/62 (14%)

Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103
            C CP  FTGV+CET   K  C    +   CR+G  C       I    C+    Y   +C
Sbjct: 1152 CNCPGDFTGVHCET--NKDEC---NEAMPCRNGGSCY----NSIGFFNCTCTNQYVGKLC 1202

Query: 1104 EL 1105
            E+
Sbjct: 1203 EV 1204



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 13/40 (32%), Positives = 20/40 (50%)

Query: 1311 PEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            P +   C    C NG  C ++  +Y C+C   ++GK C D
Sbjct: 2244 PVRVDSCIDKTCSNGGRCINITYSYSCECPLVYSGKHCDD 2283



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/45 (31%), Positives = 17/45 (37%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            C   R  C   PC NG  C +L   + C C   + G  C     P
Sbjct: 75   CEYDRDECIGKPCSNGGTCVNLKGGFDCICPANYIGLHCLQVLNP 119



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 15/64 (23%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C  GFTG +CE +     C+   +G  C S S            + C+  A +T +
Sbjct: 513  YSCACHTGFTGKDCEIVKDSCGCQ---NGGTCNSTS------------RSCTCPAMFTGS 557

Query: 1102 VCEL 1105
            +CE+
Sbjct: 558  ICEI 561



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 13/32 (40%), Positives = 16/32 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CS +PC NG  CS      +C+C    TG  C
Sbjct: 1132 CSVSPCLNGGTCSTNGKLAVCNCPGDFTGVHC 1163



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 13/32 (40%), Positives = 16/32 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+ +PC NG  C      Y C C  G TG +C
Sbjct: 4402 CALSPCKNGGFCLGDLSGYTCTCASGWTGVNC 4433



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 2/41 (4%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079
            ++ +TC C  G+TGVNCE     A   V+G    C +G  C
Sbjct: 4417 LSGYTCTCASGWTGVNCEIRDFCALASVNGPA--CFNGGVC 4455



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  S C S PC NG  C+++   + C C     G  C
Sbjct: 1913 CRESDS-CYSLPCLNGGTCTNIGGRFNCTCLSAFVGDMC 1950



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 28/107 (26%), Positives = 34/107 (31%), Gaps = 10/107 (9%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYS 1572
            C  + C   +KC        C C A   G  C    + C   PC     C  + T  GY 
Sbjct: 2585 CESNPCMNEAKCTEMIRDFQCECSAEFTGKNCELRKTNCSSNPCQNGGTC--NVTDTGYK 2642

Query: 1573 CACEPGY----TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615
            C C  GY        S     G + C G     S      C+ T  Y
Sbjct: 2643 CECFVGYIGKECENVSSVDNCGNQTCSGRGNCISQVSSYLCNCTTDY 2689



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 3/44 (6%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKAS---CEVDGDGSICRSGSQC 1079
            +  F C+C   FTG NCE   T  S   C+  G  ++  +G +C
Sbjct: 2600 IRDFQCECSAEFTGKNCELRKTNCSSNPCQNGGTCNVTDTGYKC 2643



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C   +  C+ A PC NG  C +    + C C   + GK C
Sbjct: 1163 CETNKDECNEAMPCRNGGSCYNSIGFFNCTCTNQYVGKLC 1202



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 10/32 (31%), Positives = 16/32 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  C     C     +Y+C+C   ++GKDC
Sbjct: 2663 CGNQTCSGRGNCISQVSSYLCNCTTDYSGKDC 2694



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 11/32 (34%), Positives = 16/32 (50%)

Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            C+NG  C++   +Y C C  G  G+ C    G
Sbjct: 4449 CFNGGVCTNTPTSYTCTCARGFHGRRCEAGCG 4480



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 16/50 (32%), Positives = 22/50 (44%), Gaps = 2/50 (4%)

Query: 1505 ENVRDG-CQSRADCMLSICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSAC 1552
            E +RD  C+++A C  + C     C  + D   C C   G  GP C   C
Sbjct: 3611 EMLRDSICEAKAPCSGAPCKNGGICTENGDLFNCNCTSTGFTGPTCEEPC 3660


>SB_28495| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 6753

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 7/124 (5%)

Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGA 1559
            V++   + CQ    C    C     C  S  S TC C +  +G  C   +  C   PC  
Sbjct: 3828 VKQTKMELCQVADQCSSYPCKNGGTCTNSGQSYTCNCTSDYIGEHCEEKIDPCNPTPCQN 3887

Query: 1560 ARCVPDQTPKGYSCACEPGYT--LTTSGCIESGKEE-CPGGWWGGSACGPCACDVTRGYH 1616
                   +   Y+C C PGYT    T+   E    + C  G     + G  +C+ +  Y 
Sbjct: 3888 GGTCASPSSSNYTCTCAPGYTGENCTNNVNECNDPDLCKNGGVCKDSFGSYSCNCSSAYS 3947

Query: 1617 -PHC 1619
              HC
Sbjct: 3948 GKHC 3951



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 16/33 (48%), Positives = 21/33 (63%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            +CSS PC NG  C++   +YIC C    TGK+C
Sbjct: 3058 QCSSYPCKNGGSCANSGSSYICTCTSEFTGKNC 3090



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 28/98 (28%), Positives = 34/98 (34%), Gaps = 6/98 (6%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQT 1567
            CQ    C    C     C  S  S  CTC +   G  C     AC   PCG        +
Sbjct: 3053 CQVADQCSSYPCKNGGSCANSGSSYICTCTSEFTGKNCEIVRDACNPTPCGNGATCNILS 3112

Query: 1568 PKGYSCACEPGYTLTTSGCIESGKE-ECPGGWWGGSAC 1604
               Y+C C  GY  T   C ++  E + P     G  C
Sbjct: 3113 AVNYTCTCAVGY--TGKNCTQNVNECDDPARCQNGGTC 3148



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDCADS 1351
            C EK   C+  PC NG  C S     Y C C  G+TG++C ++
Sbjct: 3873 CEEKIDPCNPTPCQNGGTCASPSSSNYTCTCAPGYTGENCTNN 3915



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDCADS 1351
            C   R  C+  PC NGA C+ L    Y C C  G+TGK+C  +
Sbjct: 3090 CEIVRDACNPTPCGNGATCNILSAVNYTCTCAVGYTGKNCTQN 3132



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CS +PC NG  C+ + + Y C C++G  GK C
Sbjct: 3582 CSKSPCLNGGTCTIVGEDYNCTCRQGLIGKQC 3613



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 14/39 (35%), Positives = 22/39 (56%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            +CSS PC NG  C++   +Y C+C   + G+ C +   P
Sbjct: 3841 QCSSYPCKNGGTCTNSGQSYTCNCTSDYIGEHCEEKIDP 3879



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 17/41 (41%), Positives = 21/41 (51%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            E    C + PC NG  C +L   Y CDC   +TGK+C   T
Sbjct: 2573 EDVDECFNDPCTNGGACINLPGDYECDCPNKYTGKNCEKRT 2613



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 1546 PQCVSACELGPCGA-ARCVPDQTPKGYSCACEPGYTLTTSGCI-ESGKEECPGGWWGGSA 1603
            P     C+  PCGA A C  +     Y+CAC+PGY       I E   + C  G    + 
Sbjct: 333  PVSFEPCDSKPCGAGATCTHNLVAWNYTCACKPGYYGDNCADIDECTNKPCLNGGSCTNL 392

Query: 1604 CGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634
             G   C    GY   C K    C  + N+YK
Sbjct: 393  QGDYRCSCVSGY---CGK---YCQSRCNNYK 417



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 14/32 (43%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C++ PC NG  C++L   Y C C  G+ GK C
Sbjct: 378  CTNKPCLNGGSCTNLQGDYRCSCVSGYCGKYC 409



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSS-APCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C   A C NG  C DL  +Y C C   H G+DC
Sbjct: 3129 CTQNVNECDDPARCQNGGTCQDLHGSYNCKCSPLHAGRDC 3168



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 12/34 (35%), Positives = 20/34 (58%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            +C++ PC N   C+ ++  + C C  G  GKDC+
Sbjct: 4731 KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 4764



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 6/60 (10%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG-GILCQGCSIDAAYTT 1100
            ++CQC  G+TG +CE+ + +  C V G   +C S  +C+   +G G LC G   +A  T+
Sbjct: 621  YSCQCLAGYTGQHCESDVDE--CLVPG---VCSSPKECINSIDGYGCLCPGMKFNANCTS 675



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            +C+  PC NGA C +    + C C  G TGKDC+
Sbjct: 4142 KCALDPCKNGATCHNGPRDFTCTCVNGFTGKDCS 4175



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 4/54 (7%)

Query: 1296 DLNSYV-ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            DL+ +  A +G L+   +K   C+S PC NG +C+     Y C C  G  G +C
Sbjct: 2779 DLSGFAHALSGELSAVVDK---CTSFPCQNGGKCTPTDSDYYCTCTSGFNGTNC 2829



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 9/85 (10%)

Query: 1499 NRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELG 1555
            N   +RE +   C S   C L  C   + C       TCTC  G  G  C   V+ CE  
Sbjct: 4128 NAYKIRERI---CTSVDKCALDPCKNGATCHNGPRDFTCTCVNGFTGKDCSQDVNECEST 4184

Query: 1556 PCGA-ARCVPDQTPKGYSCACEPGY 1579
            PC     C+       +SC C+ G+
Sbjct: 4185 PCNENQNCI--NAFGSFSCVCKDGF 4207



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C + PC NG  C ++   Y C C +G  GK+C
Sbjct: 1871 CLNKPCLNGGSCFNMDGEYRCKCAKGFCGKNC 1902



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 4/37 (10%)

Query: 1317 CSSAPCYNGAECSD---LWDTYICDCKEGHTGKDCAD 1350
            C S PC  GA C+     W+ Y C CK G+ G +CAD
Sbjct: 339  CDSKPCGAGATCTHNLVAWN-YTCACKPGYYGDNCAD 374



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAP-CYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+    C NG  C D + +Y C+C   ++GK C
Sbjct: 3912 CTNNVNECNDPDLCKNGGVCKDSFGSYSCNCSSAYSGKHC 3951



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348
            C+S PC  G  C+ L  +  Y C C  G+TG+ C
Sbjct: 601  CTSVPCGIGGNCTSLDNYGLYSCQCLAGYTGQHC 634



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            +++TC C  G+TG NC   + + +     D  +C++G  C    +       C+  +AY+
Sbjct: 3897 SNYTCTCAPGYTGENCTNNVNECN-----DPDLCKNGGVC----KDSFGSYSCNCSSAYS 3947

Query: 1100 TAVCE 1104
               CE
Sbjct: 3948 GKHCE 3952



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 6/75 (8%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSS-TCTCEAGRVGPQCV---SAC-ELGPCGAARCVPD 1565
            C   + C+L  C     C    ++   CTC     G  C    + C ++ PC    C   
Sbjct: 2303 CLGFSKCVLKPCQNGGTCNPLDNTGYNCTCTPRYRGFNCTILRTVCTDVQPCDKGNCSMI 2362

Query: 1566 QTPKG-YSCACEPGY 1579
              P G Y C C PGY
Sbjct: 2363 SIPDGTYKCTCIPGY 2377



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 20/64 (31%), Positives = 23/64 (35%), Gaps = 4/64 (6%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELG-PCGAARCVPDQTPKGYS 1572
            C    C    KC  +     CTC +G  G  C   +  C  G PC     V   T   Y 
Sbjct: 2798 CTSFPCQNGGKCTPTDSDYYCTCTSGFNGTNCEKDIDECATGNPCTGVANVCHNTYGSYE 2857

Query: 1573 CACE 1576
            C CE
Sbjct: 2858 CMCE 2861



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC-ADSTGP 1354
            C +  + C S PC     C + + ++ C CK+G     C  D T P
Sbjct: 4174 CSQDVNECESTPCNENQNCINAFGSFSCVCKDGFKDVACQIDFTDP 4219



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 1/53 (1%)

Query: 1317 CSSAPCYNGAECSDLWDT-YICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNP 1368
            C+  PC NG  C     + Y C C  G TG +C    G          ++F+P
Sbjct: 4402 CTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETGLGSTNSLSQLNQVAFDP 4454



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC-ADSTGP 1354
            C      C S+PC     C + + ++ C CK+G    +C  D T P
Sbjct: 4763 CSLDVDECKSSPCNKNQNCINSFGSFTCVCKDGLKADNCETDFTDP 4808



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 17/89 (19%)

Query: 1262 LQIGGLPNIPSS-FQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA 1320
            +++  LP+ PSS + +K    V       +  K  D+   +AD GT          CSS 
Sbjct: 1267 IELRTLPSSPSSDYVIKETSMV------MLGRKVRDVRQAIADAGT---------PCSSN 1311

Query: 1321 PCYNGAECSD-LWDTYICDCKEGHTGKDC 1348
            PC NG  C++     Y C C    +G+ C
Sbjct: 1312 PCQNGGTCTEAAAGRYSCACPVRFSGEHC 1340



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)

Query: 1315 SRCSSAPCYNGAECSDLWDT-YICDCKEGHTGKDC 1348
            S+C   PC NG  C+ L +T Y C C   + G +C
Sbjct: 2307 SKCVLKPCQNGGTCNPLDNTGYNCTCTPRYRGFNC 2341



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 3/49 (6%)

Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC--ADSTGPPWRFGGDG 1362
            C+  PC NG  C       Y C C  G TG +C  A  +G    F  DG
Sbjct: 4991 CTKNPCLNGGTCIPSGPSVYTCTCTPGVTGANCETACKSGIDLVFAVDG 5039


>SB_786| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1427

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 51/208 (24%), Positives = 74/208 (35%), Gaps = 31/208 (14%)

Query: 1507 VRDGCQSRADCMLSICPP----YSKCV-TSWDSSTCTCEAGRVGPQCVSACELGPC-GAA 1560
            +++G +S   C+  +C P    + +C+  + D   C C+AG  G  C + C   PC    
Sbjct: 152  IQEGTESY-QCVKKMCEPNPCQHGRCIEVNDDDYQCACDAGYTGKNCENFCSPNPCKNNG 210

Query: 1561 RCVPDQTPKGYSCACEPGYTLTTSGCIE-SGKEECPGGWWGGSACGPCACDVTRGYHPHC 1619
             CV      GY C C+  +       ++      C          G C  D   GY   C
Sbjct: 211  VCV--SRGVGYHCKCKRDFKGPHCEMVDMCDMNPCKN--------GRCVADEKAGYKCVC 260

Query: 1620 NKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
            +      +C EN+        C+P  C   G   S  +    QC CR G  G  C+    
Sbjct: 261  HSGFVGKNCDENY--------CVPNPCLNGGICKSVADKGY-QCKCREGYNGPHCERSPC 311

Query: 1680 AYAEVTPNSGCEVVYD----GCPRSFAG 1703
            A         C V Y      CP  + G
Sbjct: 312  APNPCLNGGTCVVFYTVHLCKCPAHYRG 339



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 8/73 (10%)

Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT-YICDCKEG 1342
            C++D    +K +  + +V  N     C E  + C   PC NG  C  + D  Y C C+EG
Sbjct: 248  CVADEKAGYKCVCHSGFVGKN-----CDE--NYCVPNPCLNGGICKSVADKGYQCKCREG 300

Query: 1343 HTGKDCADSTGPP 1355
            + G  C  S   P
Sbjct: 301  YNGPHCERSPCAP 313



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 7/58 (12%)

Query: 1301 VADNGTLAGCPE-------KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            VAD G    C E       +RS C+  PC NG  C   +  ++C C   + G  C  S
Sbjct: 288  VADKGYQCKCREGYNGPHCERSPCAPNPCLNGGTCVVFYTVHLCKCPAHYRGNRCEAS 345



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/41 (34%), Positives = 19/41 (46%)

Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            +  C   PC +G       D Y C C  G+TGK+C +   P
Sbjct: 163  KKMCEPNPCQHGRCIEVNDDDYQCACDAGYTGKNCENFCSP 203


>SB_57511| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 879

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 20/180 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C    C     C  +  S TCTC A   GP C   V+ C   PC     C    T   Y
Sbjct: 575  ECATDPCDNGGTCANTDGSYTCTCTAAWTGPTCKQDVNECLNNPCVYGGTCT--NTVGDY 632

Query: 1572 SCACEPGYTLTTSGCIESGKEEC-------PGGWWGGSACGPCACDVTRGYHPHCNKENG 1624
            SCAC  G+  T   C +   +EC        G  +       CAC V      +C+++  
Sbjct: 633  SCACVQGW--TGKDC-DQDVDECVANPCANQGTCYNNDGSYTCAC-VAGRTGLNCDQDVN 688

Query: 1625 KCHCK--ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682
            +C     +N      T     C C AA +   +C+    +C   P V G  C      Y+
Sbjct: 689  ECATDPCDNGGTCANTDGSYTCTCTAAWT-GPTCKQDVNECLNNPCVYGGTCTNTVGDYS 747



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 48/180 (26%), Positives = 68/180 (37%), Gaps = 19/180 (10%)

Query: 1508 RDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            +D  Q   +C+ + C     C  +  S TC C AGR G  C   V+ C   PC     C 
Sbjct: 643  KDCDQDVDECVANPCANQGTCYNNDGSYTCACVAGRTGLNCDQDVNECATDPCDNGGTCA 702

Query: 1564 PDQTPKGYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCN 1620
               T   Y+C C   +T  T      E     C  G    +  G  +C   +G+    C+
Sbjct: 703  --NTDGSYTCTCTAAWTGPTCKQDVNECLNNPCVYGGTCTNTVGDYSCACVQGWTGKDCD 760

Query: 1621 KENGKCHCKENHYKPEGTAECLPCQCY-AAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
            ++  +C+   N    +GT       CY   GS   +C A     +C   V   A D C N
Sbjct: 761  QDINECY--NNPCANQGT-------CYNNDGSYTCACVAGWTGLNCDQDVNECATDPCDN 811



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 15/178 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELG-PC-GAARCVPDQTPKG 1570
            +C L  C     CV +  S  C C A   GP C   V+ C    PC     C    T   
Sbjct: 460  ECALKPCAYGGSCVNTMGSYQCLCTAQWQGPTCTTDVNECAASPPCVNGGSCT--NTAGD 517

Query: 1571 YSCACEPGYTLTTSG--CIESGKEEC--PGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
            Y CAC  G+     G    E     C   G  +       CAC V      +C+++  +C
Sbjct: 518  YHCACVQGWMGKNCGQDVDECVANPCANQGTCYNNDGSYTCAC-VAGWTGLNCDQDVNEC 576

Query: 1627 HCK--ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682
                 +N      T     C C AA +   +C+    +C   P V G  C      Y+
Sbjct: 577  ATDPCDNGGTCANTDGSYTCTCTAAWT-GPTCKQDVNECLNNPCVYGGTCTNTVGDYS 633



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C + PC  G  C++    Y C C +G TGKDC
Sbjct: 607  CKQDVNECLNNPCVYGGTCTNTVGDYSCACVQGWTGKDC 645



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C + PC  G  C++    Y C C +G TGKDC
Sbjct: 721  CKQDVNECLNNPCVYGGTCTNTVGDYSCACVQGWTGKDC 759



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C++ PC NG  C++   +Y C C    TG  C
Sbjct: 569  CDQDVNECATDPCDNGGTCANTDGSYTCTCTAAWTGPTC 607



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C++ PC NG  C++   +Y C C    TG  C
Sbjct: 683  CDQDVNECATDPCDNGGTCANTDGSYTCTCTAAWTGPTC 721



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+ S PC NG  C++    Y C C +G  GK+C
Sbjct: 492  CTTDVNECAASPPCVNGGSCTNTAGDYHCACVQGWMGKNC 531



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 10/64 (15%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            S+TC C  G+TG+NC+  + +  C  D     C +G  C A  +G   C  C+  AA+T 
Sbjct: 555  SYTCACVAGWTGLNCDQDVNE--CATDP----CDNGGTC-ANTDGSYTCT-CT--AAWTG 604

Query: 1101 AVCE 1104
              C+
Sbjct: 605  PTCK 608



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 12/39 (30%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C++ PC N   C++   +Y C C    TG  C
Sbjct: 797  CDQDVNECATDPCDNRGTCANTDGSYTCTCTAAWTGPTC 835



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    C + PC N   C +   +Y C C  G TG +C
Sbjct: 645  CDQDVDECVANPCANQGTCYNNDGSYTCACVAGRTGLNC 683



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 10/64 (15%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            S+TC C  G TG+NC+  + +  C  D     C +G  C A  +G   C  C+  AA+T 
Sbjct: 669  SYTCACVAGRTGLNCDQDVNE--CATDP----CDNGGTC-ANTDGSYTCT-CT--AAWTG 718

Query: 1101 AVCE 1104
              C+
Sbjct: 719  PTCK 722



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C + PC N   C +   +Y C C  G TG +C
Sbjct: 759  CDQDINECYNNPCANQGTCYNNDGSYTCACVAGWTGLNC 797



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 3/45 (6%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC 1557
            +C    C     C  +  S TCTC A   GP C   V+ C   PC
Sbjct: 803  ECATDPCDNRGTCANTDGSYTCTCTAAWTGPTCKQDVNECLNNPC 847



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    C + PC N   C +   +Y C C  G TG +C
Sbjct: 531  CGQDVDECVANPCANQGTCYNNDGSYTCACVAGWTGLNC 569



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 10/64 (15%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            S+TC C  G+TG+NC+  + +  C  D     C +   C A  +G   C  C+  AA+T 
Sbjct: 783  SYTCACVAGWTGLNCDQDVNE--CATDP----CDNRGTC-ANTDGSYTCT-CT--AAWTG 832

Query: 1101 AVCE 1104
              C+
Sbjct: 833  PTCK 836


>SB_45521| Best HMM Match : F5_F8_type_C (HMM E-Value=8.6e-23)
          Length = 247

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 19/43 (44%), Positives = 25/43 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C +  + C S PC NGA C+D  + Y C CK G+TG +C   T
Sbjct: 36   CQQDINECQSNPCLNGATCTDHVNRYTCSCKLGYTGIECQQET 78



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 17/34 (50%), Positives = 22/34 (64%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C S PC NGA C+D  + Y C CK G+TG +C
Sbjct: 3    NECQSNPCLNGATCTDHVNGYTCSCKLGYTGIEC 36



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TC+C+ G  G +C   ++ C+  PC       D   + Y+
Sbjct: 4    ECQSNPCLNGATCTDHVNGYTCSCKLGYTGIECQQDINECQSNPCLNGATCTDHVNR-YT 62

Query: 1573 CACEPGYT 1580
            C+C+ GYT
Sbjct: 63   CSCKLGYT 70



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  +TC C  G+TG+ C+    +A+ + D    +C   SQ +  +   I+   C   ++Y
Sbjct: 58   VNRYTCSCKLGYTGIECQQETEEATAKGDLVLLVC---SQALGVQYRSIIPDACMTGSSY 114

Query: 1099 TTAVCELR 1106
                 ELR
Sbjct: 115  YDNGYELR 122


>SB_18560| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1937

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 55/193 (28%), Positives = 68/193 (35%), Gaps = 28/193 (14%)

Query: 1513 SRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG--PQC--VSACELG-PCGAARCVPDQT 1567
            S   C   +C  +++C T      C CE G  G    C  ++ CE    C   + V   T
Sbjct: 835  SSVACGGKVCHTHAECFTYQGQKQCVCERGYQGNGEDCKDINECEQNHECDPLKAVCTNT 894

Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC---GPCACDVTRGYHPHCNKENG 1624
               YSC C PGY     G    G+   P    GG  C   G C  D   G    C    G
Sbjct: 895  EGSYSCTCRPGY----GG---DGRTCTPISSCGGEVCHQFGECVTDDDTG-RKRCQCRVG 946

Query: 1625 KCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRA--C---DAC 1677
                + N        EC+P      GS NS C    G  +C CR G   +   C   D C
Sbjct: 947  ---FRGNGVDCYDMDECIPL-LRTCGS-NSLCRNTLGGYECVCRRGFTKKEGNCINIDEC 1001

Query: 1678 ANAYAEVTPNSGC 1690
                    PN+ C
Sbjct: 1002 EPGRNRCDPNADC 1014



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 16/115 (13%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSS-----TCTCEAGRVGPQCVSA----CELGPCGA-A 1560
            C+S   C   +C    +CV   +S      TC C+ G  G   +      C  GPC   A
Sbjct: 1320 CKSDGTCEGKVCDFNGECVAKNNSDGETERTCRCKEGFEGDGIICTDQDECLKGPCPQNA 1379

Query: 1561 RCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615
            +CV +     Y C C PGY      C    ++ C     GGS      C+  +G+
Sbjct: 1380 KCVNNFG--SYLCICNPGYKKVNGKC----EKLCIRCMNGGSCVENNGCECPKGF 1428



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 16/116 (13%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDS--STCTCEAG--RVGPQCVSACELGP----CGAARC 1562
            C   + C   +C  + +CVT  D+    C C  G    G  C    E  P    CG +  
Sbjct: 913  CTPISSCGGEVCHQFGECVTDDDTGRKRCQCRVGFRGNGVDCYDMDECIPLLRTCG-SNS 971

Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCI-----ESGKEECPGGWWGGSACG--PCACDV 1611
            +   T  GY C C  G+T     CI     E G+  C       +  G   CAC V
Sbjct: 972  LCRNTLGGYECVCRRGFTKKEGNCINIDECEPGRNRCDPNADCRNTVGSFQCACQV 1027



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 30/165 (18%)

Query: 1511 CQSRADCML--SICPPYSKCVTSWDSSTCTCEAGRV--GPQCVS--ACELGPCG-AARCV 1563
            C+   +C L  + C   ++CV    S  C C  G V  G  C S   CE   C     CV
Sbjct: 1279 CRDIDECALGHANCHRKAECVNQLGSFVCRCVIGYVGNGVDCKSDGTCEGKVCDFNGECV 1338

Query: 1564 PDQTPKG---YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620
                  G    +C C+ G+     G I + ++EC          GPC        +  C 
Sbjct: 1339 AKNNSDGETERTCRCKEGF--EGDGIICTDQDEC--------LKGPCP------QNAKCV 1382

Query: 1621 KENGK--CHCKENHYKPEGTAECLPCQCYAAGS--ENSSCEAATG 1661
               G   C C   + K  G  E L  +C   GS  EN+ CE   G
Sbjct: 1383 NNFGSYLCICNPGYKKVNGKCEKLCIRCMNGGSCVENNGCECPKG 1427



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 6/67 (8%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAG--RVGPQCVSACELGPCGAARCVPD--- 1565
            C  + +C+   CP  +KCV ++ S  C C  G  +V  +C   C +       CV +   
Sbjct: 1364 CTDQDECLKGPCPQNAKCVNNFGSYLCICNPGYKKVNGKCEKLC-IRCMNGGSCVENNGC 1422

Query: 1566 QTPKGYS 1572
            + PKG+S
Sbjct: 1423 ECPKGFS 1429



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 10/82 (12%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP---QCVSA--CELGP--CGA-ARCVPDQTPKGYSC 1573
            C     C+T      C C  G  G     C  A  C L    C A A C+   T   Y C
Sbjct: 672  CHSLGVCITFQGRKECRCNYGYRGDGVSYCEDADECTLNRYRCDANAECI--NTVGSYRC 729

Query: 1574 ACEPGYTLTTSGCIESGKEECP 1595
             C+ GYT     C E+ +  CP
Sbjct: 730  KCKTGYTGDGKTCTEAEEFYCP 751



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 43/173 (24%), Positives = 56/173 (32%), Gaps = 34/173 (19%)

Query: 1519 LSICPPYSKCVTSWDSSTCTCEAGRVGPQ--CVSACELGPCGA------ARCVPDQTPKG 1570
            L  C P + C+ +  S  C C++G  G    C        CG       A C   Q  K 
Sbjct: 799  LDRCDPNADCIDTVGSYRCACKSGYTGDGSICTKVPSSVACGGKVCHTHAECFTYQGQK- 857

Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP--CACDVTRGYHPHCNKENGKCHC 1628
              C CE GY      C +    EC         C P    C  T G +         C C
Sbjct: 858  -QCVCERGYQGNGEDCKDI--NECE----QNHECDPLKAVCTNTEGSY--------SCTC 902

Query: 1629 KENHYKPEGTAECLPCQ------CYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
            +   Y  +G   C P        C+  G   +  +    +C CR G  G   D
Sbjct: 903  RPG-YGGDGRT-CTPISSCGGEVCHQFGECVTDDDTGRKRCQCRVGFRGNGVD 953



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 9/78 (11%)

Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGRVGP--QCVSACEL---GPCGA-ARC 1562
            C+   +C L+   C   ++C+ +  S  C C+ G  G    C  A E      C   A+C
Sbjct: 701  CEDADECTLNRYRCDANAECINTVGSYRCKCKTGYTGDGKTCTEAEEFYCPQKCHPNAKC 760

Query: 1563 VPDQTPKGYSCACEPGYT 1580
            V      G  C C PGYT
Sbjct: 761  VR-LAVGGQVCVCLPGYT 777


>SB_34444| Best HMM Match : Cadherin (HMM E-Value=0.0043)
          Length = 205

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 24/70 (34%), Positives = 41/70 (58%), Gaps = 1/70 (1%)

Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQ 242
           N+ + Y+I+ GNT   F +D+++G++ LV  L+ E++ SY L + + DG    R+   T 
Sbjct: 26  NANVSYSIVSGNTGAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGMPVIRTQVPTS 85

Query: 243 LLINIRDVND 252
           L I + D  D
Sbjct: 86  LRIKLIDTVD 95



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 8/80 (10%)

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GV 558
           +NA ++YS+ S   N   A H     ++  TG I     L+RE ++ Y LTV + DG  V
Sbjct: 25  MNANVSYSIVS--GNTGAAFH-----VDNVTGEIKLVSKLEREKITSYTLTVGSADGMPV 77

Query: 559 PSLSDTTDVEISVVDVNDNE 578
                 T + I ++D  D E
Sbjct: 78  IRTQVPTSLRIKLIDTVDLE 97


>SB_26697| Best HMM Match : EGF (HMM E-Value=7.5e-34)
          Length = 684

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 19/43 (44%), Positives = 25/43 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C +  + C S PC NGA C+D  + Y C CK G+TG +C   T
Sbjct: 473  CQQDINECQSNPCLNGATCTDHVNRYTCSCKLGYTGIECQQET 515



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC NGA C+D  + Y C CK G+TG +C
Sbjct: 435  CETDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIEC 473



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TC+C+ G  G +C   ++ C+  PC       D   + Y+
Sbjct: 441  ECQSNPCLNGATCTDHVNGYTCSCKLGYTGIECQQDINECQSNPCLNGATCTDHVNR-YT 499

Query: 1573 CACEPGYT 1580
            C+C+ GYT
Sbjct: 500  CSCKLGYT 507



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 1315 SRCSSAPCYNGAECSDLW--DTYICDCKEGHTGKDC 1348
            S C S PC +G+ C   +  DTY C C +G+TG+ C
Sbjct: 400  SPCQSDPCLHGSRCLATYTDDTYTCACLQGYTGRHC 435



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 1037 YPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQCVAR-REGGILCQ-- 1090
            Y   ++TC C +G+TG +CET + +       +G+ C    +G  C  +    GI CQ  
Sbjct: 417  YTDDTYTCACLQGYTGRHCETDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIECQQD 476

Query: 1091 --GCSIDAAYTTAVCELRARSFPVSSFLTFPGLK 1122
               C  +     A C      +  S  L + G++
Sbjct: 477  INECQSNPCLNGATCTDHVNRYTCSCKLGYTGIE 510



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 34/128 (26%), Positives = 46/128 (35%), Gaps = 17/128 (13%)

Query: 1549 VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGP 1606
            +S C+  PC   +RC+   T   Y+CAC  GY  T   C E+   EC       G+ C  
Sbjct: 399  LSPCQSDPCLHGSRCLATYTDDTYTCACLQGY--TGRHC-ETDINECQSNPCLNGATC-- 453

Query: 1607 CACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCR 1666
               D   GY   C        C+++        EC    C    +        T  C C+
Sbjct: 454  --TDHVNGYTCSCKLGYTGIECQQD------INECQSNPCLNGATCTDHVNRYT--CSCK 503

Query: 1667 PGVIGRAC 1674
             G  G  C
Sbjct: 504  LGYTGIEC 511



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  +TC C  G+TG+ C+    +A+ + D    +C   SQ +  +   I+   C   ++Y
Sbjct: 495  VNRYTCSCKLGYTGIECQQETEEATAKGDLVLLVC---SQALGVQYRSIIPDACMTGSSY 551


>SB_4999| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 1054

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 49/171 (28%), Positives = 66/171 (38%), Gaps = 18/171 (10%)

Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELG--PCGA-AR 1561
            C    +C L+I  CP    CV +  S TC C+ G   V   C  +  C LG   C A A 
Sbjct: 420  CDDIDECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVATCPASAD 479

Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNK 1621
            CV +     Y+C C+ GYTL  + C      EC   +          C    G    C  
Sbjct: 480  CVNNDG--SYTCRCKRGYTLKNNEC--EDVNECLDLFLNTCLFKGLDCINLPG-SLQCKC 534

Query: 1622 ENGKCHCKENHYKPEGTAECLPC--QCYAAGSENSSCEAATGQ--CHCRPG 1668
              G+    ++ Y   G  +   C    Y    +NS C+   G   C C+PG
Sbjct: 535  PAGQKWDPDSFYGTGGCVDLNECVETPYVCSGDNSICQNTEGSFTCSCKPG 585



 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 48/199 (24%), Positives = 72/199 (36%), Gaps = 23/199 (11%)

Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGRV--GPQC--VSACELGP--CGAARC 1562
            C    +C L +  CP  + CV +  S TC C+ G       C  V+ C   P  C     
Sbjct: 99   CDDIDECALGVATCPASADCVNNDGSYTCRCKRGYTLNNNTCTDVNECTEIPYVCSGENS 158

Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKE 1622
            + + T   + C+C+ GYT   S  +     + P               + R    +C   
Sbjct: 159  ICENTDGSFKCSCKSGYTPKFSEAV----GDAPANLTSCDGKTAVHSKLVRNVIRYCVNN 214

Query: 1623 NGK--CHCKENHYKPEGTAECL-PCQCYAAGSENSS-CEAATGQ--CHCRPG--VIGRAC 1674
            +G   C CK  +     T E +  C    A    S+ C    G   C C+PG  ++   C
Sbjct: 215  DGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCVNNDGSYTCRCKPGYTLVNNTC 274

Query: 1675 ---DACANAYAEVTPNSGC 1690
               D CA   A    ++ C
Sbjct: 275  KDIDECALGVATCPASADC 293



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 41/163 (25%), Positives = 60/163 (36%), Gaps = 16/163 (9%)

Query: 1549 VSACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606
            V+ C   P  C     + + T   ++C+C+ GYT   S  +     + P           
Sbjct: 49   VNECTETPYVCSGNNSICENTDGSFNCSCKSGYTPKFSEAV----GDAPANLTSCDDIDE 104

Query: 1607 CACDV-TRGYHPHCNKENGK--CHCKENHYKPEGTA----ECLPCQCYAAGSENSSCEAA 1659
            CA  V T      C   +G   C CK  +     T     EC     Y    ENS CE  
Sbjct: 105  CALGVATCPASADCVNNDGSYTCRCKRGYTLNNNTCTDVNECTEIP-YVCSGENSICENT 163

Query: 1660 TG--QCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRS 1700
             G  +C C+ G   +  +A  +A A +T   G   V+    R+
Sbjct: 164  DGSFKCSCKSGYTPKFSEAVGDAPANLTSCDGKTAVHSKLVRN 206



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 13/31 (41%), Positives = 20/31 (64%), Gaps = 2/31 (6%)

Query: 1320 APCYNGAECSDLWDTYICDCKEGHT--GKDC 1348
            +PC+  A C++   +Y+C C  G+T  GKDC
Sbjct: 615  SPCHENAACTNTKGSYLCRCNSGYTGDGKDC 645



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 17/110 (15%)

Query: 1514 RADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG--PCGAAR-CVPDQTPKG 1570
            +  C     P +SK V    ++  +C+        +  C+L    C A R CV +     
Sbjct: 395  KCSCKPGYTPKFSKAVGDAPANLTSCDD-------IDECKLNISTCPANRYCVNNDG--S 445

Query: 1571 YSCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCACDVTRGY 1615
            Y+C C+PGYTL  + C +      G   CP      +  G   C   RGY
Sbjct: 446  YTCKCKPGYTLVNNTCEDIDECALGVATCPASADCVNNDGSYTCRCKRGY 495



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 13/102 (12%)

Query: 1502 TVRENVRDGCQSRADCMLSICPPYS-KCVTSWDSSTCTCEAGRV-GPQ-------CV--S 1550
            T++ N  +      D  L+ C      C+    S  C C AG+   P        CV  +
Sbjct: 496  TLKNNECEDVNECLDLFLNTCLFKGLDCINLPGSLQCKCPAGQKWDPDSFYGTGGCVDLN 555

Query: 1551 ACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESG 1590
             C   P  C     +   T   ++C+C+PGYT T SG +  G
Sbjct: 556  ECVETPYVCSGDNSICQNTEGSFTCSCKPGYTPTFSGSVSDG 597



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 23/133 (17%)

Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            Y+C C+PGYTL  + C +   +EC     G + C P + D         N  +  C CK 
Sbjct: 218  YTCKCKPGYTLVNNTCEDI--DECA---LGVANC-PASADCVN------NDGSYTCRCKP 265

Query: 1631 NHYKPEGTAECLPCQC---YAAGSENSSCEAATGQ--CHCRPG--VIGRACDA---CANA 1680
             +     T + +  +C    A    ++ C    G   C C+ G  ++ + C A     + 
Sbjct: 266  GYTLVNNTCKDID-ECALGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCTARWSVISN 324

Query: 1681 YAEVTPNSGCEVV 1693
            + ++T N   E++
Sbjct: 325  FLQITNNERYELL 337


>SB_46333| Best HMM Match : EGF (HMM E-Value=1.10001e-40)
          Length = 580

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            C+++   C  S C   + C+   D+S   CTC AG  G  C   V  C+  PC   A C 
Sbjct: 115  CETQVKPCDSSPCKNNATCINDKDNSGYNCTCSAGFTGSDCETQVKPCDSSPCKNNATCT 174

Query: 1564 PDQTPKGYSCACEPGYT 1580
              +   GY+C C  G+T
Sbjct: 175  NKEDNSGYNCTCSAGFT 191



 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 18/165 (10%)

Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570
            C  S C   + C+   D+S   CTC AG  G  C   V  C+  PC   A C        
Sbjct: 42   CDSSPCKNNATCINKEDNSGYNCTCSAGFTGSDCETQVKPCDTIPCKNNATCTNKDDNSS 101

Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDV-TRGYHPHCNKENGKCHCK 1629
            Y+C C  G+  T S C E+  + C       +A   C  D    GY+  C+       C 
Sbjct: 102  YNCTCSTGF--TGSDC-ETQVKPCDSSPCKNNA--TCINDKDNSGYNCTCSAGFTGSDC- 155

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            E   KP    +  PC+  A  +     + +   C C  G  G  C
Sbjct: 156  ETQVKP---CDSSPCKNNATCTNKE--DNSGYNCTCSAGFTGNDC 195



 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSST--CTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            C+++   C    C   + C    D+S+  CTC  G  G  C   V  C+  PC   A C+
Sbjct: 75   CETQVKPCDTIPCKNNATCTNKDDNSSYNCTCSTGFTGSDCETQVKPCDSSPCKNNATCI 134

Query: 1564 PDQTPKGYSCACEPGYT 1580
             D+   GY+C C  G+T
Sbjct: 135  NDKDNSGYNCTCSAGFT 151



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 6/85 (7%)

Query: 1275 QVKNKDFVGCISDFYIDHKFIDLNSY--VADNG-TLAGCPEKRSRCSSAPCYNGAECSDL 1331
            QVK  D + C ++    +K  D +SY      G T + C  +   C S+PC N A C + 
Sbjct: 78   QVKPCDTIPCKNNATCTNKD-DNSSYNCTCSTGFTGSDCETQVKPCDSSPCKNNATCIND 136

Query: 1332 WDT--YICDCKEGHTGKDCADSTGP 1354
             D   Y C C  G TG DC     P
Sbjct: 137  KDNSGYNCTCSAGFTGSDCETQVKP 161



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348
            T + C  +   C S+PC N A C++  D   Y C C  G TG DC
Sbjct: 151  TGSDCETQVKPCDSSPCKNNATCTNKEDNSGYNCTCSAGFTGNDC 195



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 3/55 (5%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354
            + +G  A     +S C S+PC N A C +  D   Y C C  G TG DC     P
Sbjct: 28   SSSGACANATRVKS-CDSSPCKNNATCINKEDNSGYNCTCSAGFTGSDCETQVKP 81



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354
            T + C  +   C + PC N A C++  D  +Y C C  G TG DC     P
Sbjct: 71   TGSDCETQVKPCDTIPCKNNATCTNKDDNSSYNCTCSTGFTGSDCETQVKP 121



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            +S+ C C  GFTG +CET +         D S C++ + C+  ++       C+  A +T
Sbjct: 100  SSYNCTCSTGFTGSDCETQVKPC------DSSPCKNNATCINDKDNS--GYNCTCSAGFT 151

Query: 1100 TAVCELRAR 1108
             + CE + +
Sbjct: 152  GSDCETQVK 160



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 6/50 (12%)

Query: 1537 CTCEAGRVGPQCVSA-----CELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
            C C+ G     C +A     C+  PC   A C+  +   GY+C C  G+T
Sbjct: 22   CECQKGSSSGACANATRVKSCDSSPCKNNATCINKEDNSGYNCTCSAGFT 71



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 16/69 (23%), Positives = 30/69 (43%), Gaps = 8/69 (11%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            + + C C  GFTG +CET +         D   C++ + C  + +       C+    +T
Sbjct: 60   SGYNCTCSAGFTGSDCETQVKPC------DTIPCKNNATCTNKDDNS--SYNCTCSTGFT 111

Query: 1100 TAVCELRAR 1108
             + CE + +
Sbjct: 112  GSDCETQVK 120


>SB_49700| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 7645

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 41/138 (29%), Positives = 56/138 (40%), Gaps = 18/138 (13%)

Query: 938  DDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYL-HRTTLA-RLATVQVL 995
            D T VT  +LN      R    V +  D     + T         +R TL     TV +L
Sbjct: 6871 DYTQVTDKVLNFDVEETRIVVSVPIVDDALVEPTETFYATLTTADNRVTLGPENTTVYIL 6930

Query: 996  PFDDNICVHEPCLN---------FEECLTVLKFGNASGFVNSDSVLFRP-------IYPV 1039
              D N C  EPC N         + +C  V  F   +  +N +  +  P       +  +
Sbjct: 6931 DNDVNECDSEPCQNGGSCTDMGNYYQCACVPGFSGVNCEINVNECMSAPCKNGATCVDGI 6990

Query: 1040 TSFTCQCPEGFTGVNCET 1057
             S+TCQC  G+TGVNCET
Sbjct: 6991 NSYTCQCAVGYTGVNCET 7008



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 7/70 (10%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC---ADSTGP-PWRFGG---DG 1362
            C    + C SAPC NGA C D  ++Y C C  G+TG +C    D   P P ++GG   DG
Sbjct: 6968 CEINVNECMSAPCKNGATCVDGINSYTCQCAVGYTGVNCETNPDDCHPNPCQYGGTCVDG 7027

Query: 1363 MLSFNPLLRP 1372
            +  F  L  P
Sbjct: 7028 LDDFTCLCVP 7037



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 47/184 (25%), Positives = 69/184 (37%), Gaps = 27/184 (14%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C   ++C+   +   C C  G  G +C   +  C   PC    RC+ DQ    Y
Sbjct: 7126 ECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGGRCI-DQV-NDY 7183

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGP------CACDVTRGY------HPH 1618
             C C PG+      C E+  ++C       G+ C        C C +  GY      H  
Sbjct: 7184 ECQCLPGFV--GDNC-ETNVDDCADNPCLNGATCIDGVNDYYCVCAI--GYYSKNCEHIS 7238

Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACA 1678
            CN+ +    C  + +  E T+ C  C C   G+   S       C C  G  G  C+   
Sbjct: 7239 CNRFSVLLIC--DLFLSE-TSTCTDCTCENGGTCGVSSVYGHWFCVCPKGFKGERCEIAD 7295

Query: 1679 NAYA 1682
            N  A
Sbjct: 7296 NGCA 7299



 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 41/175 (23%), Positives = 58/175 (33%), Gaps = 12/175 (6%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS---ACELGPCG-AARCVPDQTPKGY 1571
            +CM + C   + CV   +S TC C  G  G  C +    C   PC     CV       +
Sbjct: 6974 ECMSAPCKNGATCVDGINSYTCQCAVGYTGVNCETNPDDCHPNPCQYGGTCVDGL--DDF 7031

Query: 1572 SCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHC 1628
            +C C PG T  +      E     C              C    GY   HC  +   C  
Sbjct: 7032 TCLCVPGTTGKICHININECNSNPCRNNGTCVDGINGFTCRCLEGYIGAHCEVDVNYCDS 7091

Query: 1629 KE--NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
            +   N+       +   C C A G    +C+    +C   P + G  C    N +
Sbjct: 7092 EPCMNNATCVDEQDGFTCIC-APGYTGPTCDGDIDECAFNPCLNGAECINLENGF 7145



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C      C+  PC NGAEC +L + + C C  G+TGK C     D T  P   GG
Sbjct: 7120 CDGDIDECAFNPCLNGAECINLENGFECVCLPGYTGKRCGIDIDDCTPSPCINGG 7174



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 14/34 (41%), Positives = 20/34 (58%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C S PC NG  C+D+ + Y C C  G +G +C
Sbjct: 6935 NECDSEPCQNGGSCTDMGNYYQCACVPGFSGVNC 6968



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 17/41 (41%), Positives = 20/41 (48%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A C    + C S PC N A C D  D + C C  G+TG  C
Sbjct: 7080 AHCEVDVNYCDSEPCMNNATCVDEQDGFTCICAPGYTGPTC 7120



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348
            C    + C++ PC NG  C  D    Y C C+EG TGK+C
Sbjct: 7291 CEIADNGCATKPCQNGGSCCQDPVKGYSCICREGFTGKNC 7330



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 6/65 (9%)

Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343
            CI D   D++   L  +V DN     C      C+  PC NGA C D  + Y C C  G+
Sbjct: 7176 CI-DQVNDYECQCLPGFVGDN-----CETNVDDCADNPCLNGATCIDGVNDYYCVCAIGY 7229

Query: 1344 TGKDC 1348
              K+C
Sbjct: 7230 YSKNC 7234



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+ +PC NG  C D  + Y C C  G  G +C
Sbjct: 7165 CTPSPCINGGRCIDQVNDYECQCLPGFVGDNC 7196



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 44/172 (25%), Positives = 57/172 (33%), Gaps = 16/172 (9%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  S C    +C+   +   C C  G VG  C   V  C   PC   A C+       Y
Sbjct: 7164 DCTPSPCINGGRCIDQVNDYECQCLPGFVGDNCETNVDDCADNPCLNGATCI--DGVNDY 7221

Query: 1572 SCACEPGYTLTTSGCIESGKEE----CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627
             C C  GY       I   +      C       S C  C C+            +  C 
Sbjct: 7222 YCVCAIGYYSKNCEHISCNRFSVLLICDLFLSETSTCTDCTCENGGTCGVSSVYGHWFCV 7281

Query: 1628 CKENHYKPEGTAECLPCQCYAAGSEN-SSC--EAATG-QCHCRPGVIGRACD 1675
            C +  +K E   E     C     +N  SC  +   G  C CR G  G+ C+
Sbjct: 7282 CPKG-FKGE-RCEIADNGCATKPCQNGGSCCQDPVKGYSCICREGFTGKNCE 7331



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 3/55 (5%)

Query: 1297 LNSYV---ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            +NSY    A   T   C      C   PC  G  C D  D + C C  G TGK C
Sbjct: 6990 INSYTCQCAVGYTGVNCETNPDDCHPNPCQYGGTCVDGLDDFTCLCVPGTTGKIC 7044



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S PC N   C D  + + C C EG+ G  C
Sbjct: 7044 CHININECNSNPCRNNGTCVDGINGFTCRCLEGYIGAHC 7082



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 18/66 (27%), Positives = 28/66 (42%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  FTC+C EG+ G +CE  +         D   C + + CV  ++G      C     Y
Sbjct: 7066 INGFTCRCLEGYIGAHCEVDVNYC------DSEPCMNNATCVDEQDGFT----CICAPGY 7115

Query: 1099 TTAVCE 1104
            T   C+
Sbjct: 7116 TGPTCD 7121



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 12/19 (63%), Positives = 14/19 (73%)

Query: 1038 PVTSFTCQCPEGFTGVNCE 1056
            PV  ++C C EGFTG NCE
Sbjct: 7313 PVKGYSCICREGFTGKNCE 7331



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            R I  V  + CQC  GF G NCET +   +     +G+ C  G
Sbjct: 7175 RCIDQVNDYECQCLPGFVGDNCETNVDDCADNPCLNGATCIDG 7217



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 15/51 (29%), Positives = 25/51 (49%)

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
           ++  I + I+DD  N PQ +      S D +I ++ N V+  I   D  +G
Sbjct: 694 TSKVIIIPILDDKKNEPQETFTVTVSSADSNIEISPNEVVITILDNDVSIG 744



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 17/127 (13%)

Query: 1549 VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPC 1607
            V+ C+  PC       D     Y CAC PG+  +   C E    EC       G+ C   
Sbjct: 6934 VNECDSEPCQNGGSCTDMG-NYYQCACVPGF--SGVNC-EINVNECMSAPCKNGATC--- 6986

Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667
              D    Y   C       +C+ N   P+   +C P  C   G+     +  T  C C P
Sbjct: 6987 -VDGINSYTCQCAVGYTGVNCETN---PD---DCHPNPCQYGGTCVDGLDDFT--CLCVP 7037

Query: 1668 GVIGRAC 1674
            G  G+ C
Sbjct: 7038 GTTGKIC 7044


>SB_37565| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 286

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 16/34 (47%), Positives = 25/34 (73%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            ++C S+PC NG  C+D  + YIC C+ G+TG++C
Sbjct: 3    NKCESSPCKNGGNCTDQVNNYICTCQPGYTGRNC 36



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 17/39 (43%), Positives = 25/39 (64%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CP + + C S PC NG   +D ++ Y C C+ G+TGK+C
Sbjct: 89   CPIEHNDCESCPCKNGGSYTDRFNDYTCKCQPGYTGKNC 127



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 1/60 (1%)

Query: 1289 YIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            Y D +F D         T   C      C+  PC N  +C D  + Y C C+ G +G++C
Sbjct: 107  YTD-RFNDYTCKCQPGYTGKNCEIDIDECAGNPCKNKGKCIDHVNNYTCRCQAGVSGRNC 165



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 34/132 (25%), Positives = 44/132 (33%), Gaps = 10/132 (7%)

Query: 1549 VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA 1608
            ++ CE  PC       DQ    Y C C+PGY  T   C +   E    G           
Sbjct: 2    INKCESSPCKNGGNCTDQV-NNYICTCQPGY--TGRNCEKDIPEMLKQGELNVCDRRDST 58

Query: 1609 CDVTRGYHPHCNKENGKCHC-----KENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC 1663
               T     +  K   K  C     + N   P    +C  C C   GS        T  C
Sbjct: 59   VYGTAYRTVYQLKYETKIFCCPGWKQFNISCPIEHNDCESCPCKNGGSYTDRFNDYT--C 116

Query: 1664 HCRPGVIGRACD 1675
             C+PG  G+ C+
Sbjct: 117  KCQPGYTGKNCE 128



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 18/67 (26%), Positives = 26/67 (38%), Gaps = 6/67 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC    C         ++  TC C+ G  G  C   +  C   PC    +C+ D     Y
Sbjct: 95   DCESCPCKNGGSYTDRFNDYTCKCQPGYTGKNCEIDIDECAGNPCKNKGKCI-DHV-NNY 152

Query: 1572 SCACEPG 1578
            +C C+ G
Sbjct: 153  TCRCQAG 159



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 42/176 (23%), Positives = 53/176 (30%), Gaps = 13/176 (7%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSAC-ELGPCGAARCVPDQTPKGYSCAC 1575
            C  S C     C    ++  CTC+ G  G  C     E+   G       +    Y  A 
Sbjct: 5    CESSPCKNGGNCTDQVNNYICTCQPGYTGRNCEKDIPEMLKQGELNVCDRRDSTVYGTAY 64

Query: 1576 EPGYTL---TTSGCIESGKE---ECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
               Y L   T   C    K+    CP      + C  C C     Y    N    KC   
Sbjct: 65   RTVYQLKYETKIFCCPGWKQFNISCP---IEHNDCESCPCKNGGSYTDRFNDYTCKCQPG 121

Query: 1630 ENHYKPE-GTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEV 1684
                  E    EC    C   G         T  C C+ GV GR C+    + A +
Sbjct: 122  YTGKNCEIDIDECAGNPCKNKGKCIDHVNNYT--CRCQAGVSGRNCEKVPTSCASI 175



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 16/79 (20%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV-------ARREGGILCQGCSI 1094
            +TC+C  G+TG NCE  + + +      G+ C++  +C+        R + G+  + C  
Sbjct: 114  YTCKCQPGYTGKNCEIDIDECA------GNPCKNKGKCIDHVNNYTCRCQAGVSGRNCE- 166

Query: 1095 DAAYTTAVCELRARSFPVS 1113
                 T+   +RA  F +S
Sbjct: 167  --KVPTSCASIRALGFTIS 183


>SB_34555| Best HMM Match : EGF (HMM E-Value=7.00649e-45)
          Length = 979

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 43/168 (25%), Positives = 58/168 (34%), Gaps = 22/168 (13%)

Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570
            C  S C     C    D++  TCTC +   G +C   V  C+  PC     C       G
Sbjct: 213  CDSSPCKNGGSCTNKPDNTGYTCTCPSEYTGTECETQVQPCDSSPCKNGGACANKADNSG 272

Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            Y+C C  GYT      IE   +  P          PC  D +    P  N     C C  
Sbjct: 273  YTCDCASGYT-----GIECESQVTP------CESNPCKNDGSCANKP--NNTGYTCTCTS 319

Query: 1631 NHYKPEGTAECLPCQ---CYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
             +   E   +  PC    C   G+  +  + +   C C  G  G  C+
Sbjct: 320  EYTGTECETQVQPCDSSPCKNGGACANKADNSGFTCACASGYTGIECE 367



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354
            C  +   C S+PC NG  C++  D   Y CDC  G+TG +C     P
Sbjct: 246  CETQVQPCDSSPCKNGGACANKADNSGYTCDCASGYTGIECESQVTP 292



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            C+S+   C  + C     C    +++  TCTC +   G +C   V  C+  PC     C 
Sbjct: 286  CESQVTPCESNPCKNDGSCANKPNNTGYTCTCTSEYTGTECETQVQPCDSSPCKNGGACA 345

Query: 1564 PDQTPKGYSCACEPGYT 1580
                  G++CAC  GYT
Sbjct: 346  NKADNSGFTCACASGYT 362



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 2/44 (4%)

Query: 1313 KRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354
            K  RC S+PC NG  C++  D   Y C C   +TG +C     P
Sbjct: 209  KVQRCDSSPCKNGGSCTNKPDNTGYTCTCPSEYTGTECETQVQP 252



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 10/66 (15%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARRE-GGILCQGCSIDAAY 1098
            T +TC CP  +TG  CET +         D S C++G  C  + +  G  C  C+  + Y
Sbjct: 231  TGYTCTCPSEYTGTECETQVQPC------DSSPCKNGGACANKADNSGYTCD-CA--SGY 281

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 282  TGIECE 287



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348
            C  +   C S+PC NG  C++  D   + C C  G+TG +C
Sbjct: 326  CETQVQPCDSSPCKNGGACANKADNSGFTCACASGYTGIEC 366



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 8/65 (12%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            T +TC C   +TG  CET +         D S C++G  C  + +       C+  + YT
Sbjct: 311  TGYTCTCTSEYTGTECETQVQPC------DSSPCKNGGACANKADNSGFT--CACASGYT 362

Query: 1100 TAVCE 1104
               CE
Sbjct: 363  GIECE 367



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 8/69 (11%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            + +TC C  G+TG+ CE+ +T   CE     + C++   C  +         C+  + YT
Sbjct: 271  SGYTCDCASGYTGIECESQVT--PCE----SNPCKNDGSCANKPNN--TGYTCTCTSEYT 322

Query: 1100 TAVCELRAR 1108
               CE + +
Sbjct: 323  GTECETQVQ 331



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 2/47 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354
            C  + + C S PC N   C++  +   Y C C   +TG +C     P
Sbjct: 286  CESQVTPCESNPCKNDGSCANKPNNTGYTCTCTSEYTGTECETQVQP 332



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%)

Query: 1318 SSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348
            +S+PC NGA C++  D   Y+C C    TG  C
Sbjct: 778  NSSPCKNGATCTNSADNPGYMCTCSNVFTGSTC 810


>SB_6077| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1165

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC----ADSTGPPWRFGG 1360
            C      C+ APC +G+ C DL + Y C C +G+TGKDC     + +  P ++GG
Sbjct: 402  CSVNIDDCADAPCQHGSTCIDLVNDYKCSCLQGYTGKDCHIDINECSSNPCQYGG 456



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S+PC NGA C DL D + C C+ G  G++C
Sbjct: 250  CQVNIDECASSPCKNGATCEDLVDEFRCQCQPGFKGQNC 288



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 46/168 (27%), Positives = 56/168 (33%), Gaps = 14/168 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  + C  Y  C       TC C  G  G  C   +  CE  PC   A C  D   KGY
Sbjct: 940  DCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL-KGY 998

Query: 1572 SCACEPGYTLTTSGCIESGKEEC--PGGWWGGSACGPCACDVTRGYHPHCNKENGKC--- 1626
            SC+C  G T           + C   G      +   C C  +    P C +    C   
Sbjct: 999  SCSCPTGVTGRHCDVSICDSKPCRNNGSCVLTQSGYQCLC-ASSFTSPQCQRSIDDCEHA 1057

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            HC  N      +     C C   G     CE    +CH +P   G  C
Sbjct: 1058 HCL-NGATCVDSDNAYKCSC-LEGYYGKHCE-LIDRCHSQPCQNGATC 1102



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C+ + C   S C+   ++  CTC  G  G  C   +  C+  PC       D     Y 
Sbjct: 294  ECIGAACANGSTCIDLVNAYQCTCLPGFTGRHCDVDIDECQSNPCQHGSACMDGV-SSYQ 352

Query: 1573 CACEPGYT 1580
            C C+PGYT
Sbjct: 353  CICQPGYT 360



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            GTL  C      C  +PC NGA C DL + + C C  G  G+ CA
Sbjct: 589  GTL--CDVNVDECEDSPCANGASCEDLINDFRCHCPAGFQGRTCA 631



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 15/39 (38%), Positives = 24/39 (61%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+++PC N A+C+D+   Y C C+ G+TG  C
Sbjct: 630  CAVDINECATSPCLNEAKCTDVVSGYRCTCRSGYTGTRC 668



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C      C+++PC N A C+DL + + C C  G+ G+ CA    D T  P + GG
Sbjct: 820  CEANIDDCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGG 874



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 48/189 (25%), Positives = 63/189 (33%), Gaps = 27/189 (14%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQT----PKGY 1571
            DC    C     CV +    TC C  G  G  C  + E+  CG+  C+ + T        
Sbjct: 864  DCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINC--SIEMDECGSYPCLNNGTCVDGRNRV 921

Query: 1572 SCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            +C C  G+T       E   ++C P        C     D T   +P    E     C  
Sbjct: 922  TCTCAVGFT---GQFCEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGET----CAT 974

Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSC--EAATG-QCHCRPGVIGRACDACANAYAEVTPN 1687
                P    E  PCQ       N++C  +   G  C C  GV GR CD           N
Sbjct: 975  ----PIDLCEAHPCQ------NNATCRMDPLKGYSCSCPTGVTGRHCDVSICDSKPCRNN 1024

Query: 1688 SGCEVVYDG 1696
              C +   G
Sbjct: 1025 GSCVLTQSG 1033



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC N A C DL + + C C +G TG+ C
Sbjct: 136  CETNYNDCHSNPCQNNATCQDLINDFSCQCPQGITGQTC 174



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 48/180 (26%), Positives = 62/180 (34%), Gaps = 29/180 (16%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPD 1565
            C+S+ + C  S C   + C+   ++ TC C  G  G  C   V  CE  PC   A C  +
Sbjct: 554  CESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLCDVNVDECEDSPCANGASC--E 611

Query: 1566 QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625
                 + C C  G+   T  C     E         + C     DV  GY   C      
Sbjct: 612  DLINDFRCHCPAGFQGRT--CAVDINECATSPCLNEAKC----TDVVSGYRCTCRSGYTG 665

Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRAC----DACAN 1679
              C+ +        EC    C   G     C   T   +C C PG  G  C    D CAN
Sbjct: 666  TRCERD------IDECSSSPCVNGG----LCVDYTNYFECLCHPGYGGDRCEINIDDCAN 715



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/47 (40%), Positives = 22/47 (46%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A + T   C      C  A C NGA C D  + Y C C EG+ GK C
Sbjct: 1039 ASSFTSPQCQRSIDDCEHAHCLNGATCVDSDNAYKCSCLEGYYGKHC 1085



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 16/39 (41%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + CSS+PC NG  C+D    Y C C  G +G++C
Sbjct: 212  CEVDVNECSSSPCVNGGVCADGLGEYKCICPSGFSGENC 250



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 52/200 (26%), Positives = 76/200 (38%), Gaps = 30/200 (15%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  S C     CV   +   C C  G  G +C   +  C   PC       D     ++
Sbjct: 674  ECSSSPCVNGGLCVDYTNYFECLCHPGYGGDRCEINIDDCANKPCLHNGNCTDYV-NYFT 732

Query: 1573 CACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            CAC  GYT  T  C E   ++C P     G +C     D+  GY  H        +C+ +
Sbjct: 733  CACAVGYTGRT--C-EVNIDDCSPSPCRHGGSCQ----DLVTGYLCHWPAGFKGSNCETD 785

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPGVIGRACDACAN--AYAEVTPN 1687
                    EC    C      N +C    A+  C C+PG  G  C+A  +  A +    N
Sbjct: 786  ------IDECATNPC----DNNGTCVDRVASYDCVCKPGFTGTRCEANIDDCATSPCLNN 835

Query: 1688 SGC-EVVYD---GCPRSFAG 1703
            + C +++ D    CP  + G
Sbjct: 836  AICTDLINDFHCACPAGYQG 855



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 47/189 (24%), Positives = 63/189 (33%), Gaps = 32/189 (16%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  + C   + C    +  +C C  G  G  C   +  C+  PC       +    G++
Sbjct: 142  DCHSNPCQNNATCQDLINDFSCQCPQGITGQTCNTDIDECQSSPCKHQGTCQNYLG-GFN 200

Query: 1573 CACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCH-- 1627
            C C  GY+  T      E     C  G       G   C    G+   +C     +C   
Sbjct: 201  CLCRHGYSGITCEVDVNECSSSPCVNGGVCADGLGEYKCICPSGFSGENCQVNIDECASS 260

Query: 1628 -CKENHYKPEGTAECLPCQCYAAGSENSSCEA----------ATG----------QCHCR 1666
             CK N    E   +   CQC   G +  +CE           A G          QC C 
Sbjct: 261  PCK-NGATCEDLVDEFRCQCQP-GFKGQNCETNINECIGAACANGSTCIDLVNAYQCTCL 318

Query: 1667 PGVIGRACD 1675
            PG  GR CD
Sbjct: 319  PGFTGRHCD 327



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C  A C NG+ C DL + Y C C  G TG+ C
Sbjct: 288  CETNINECIGAACANGSTCIDLVNAYQCTCLPGFTGRHC 326



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 1284 CISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH 1343
            CI D   D+K   L  Y   +     C    + CSS PC  G  C +L + Y C C +G+
Sbjct: 420  CI-DLVNDYKCSCLQGYTGKD-----CHIDINECSSNPCQYGGTCLNLLNGYACLCIDGY 473

Query: 1344 TGKDC 1348
            TG +C
Sbjct: 474  TGLNC 478



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 15/33 (45%), Positives = 18/33 (54%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C S PC N   C DL   + C C  G +GKDC+
Sbjct: 371  CLSRPCLNNGMCLDLVSDFHCTCPTGFSGKDCS 403



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C S PC +G+ C D   +Y C C+ G+TG+ C
Sbjct: 326  CDVDIDECQSNPCQHGSACMDGVSSYQCICQPGYTGQYC 364



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 16/39 (41%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  K + C S+ CY  A C D  + Y C C  G TG  C
Sbjct: 554  CESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLC 592



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 40/167 (23%), Positives = 56/167 (33%), Gaps = 13/167 (7%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C++  D C  + C     CV    S  C C+ G  G +C   +  C   PC     +   
Sbjct: 782  CETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRCEANIDDCATSPC-LNNAICTD 840

Query: 1567 TPKGYSCACEPGYTLTTS--GCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCNKEN 1623
                + CAC  GY   T      +   + C  G     A     C    G+   +C+ E 
Sbjct: 841  LINDFHCACPAGYQGQTCAINVDDCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCSIEM 900

Query: 1624 GKC---HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667
             +C    C  N    +G    + C C A G     CE     C   P
Sbjct: 901  DECGSYPCLNNGTCVDGRNR-VTCTC-AVGFTGQFCEVNIDDCDPAP 945



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 16/40 (40%), Positives = 18/40 (45%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C  APC N   C DL   + C C  G TG+ CA
Sbjct: 934  CEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCA 973



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 4/48 (8%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C++ PC +   C+D  + + C C  G+TG+ C     D +  P R GG
Sbjct: 713  CANKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNIDDCSPSPCRHGG 760



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 1303 DNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYI-CDCKEGHTGKDC 1348
            DN     C    S C +  C NG  C     TY  C+C +G+TG DC
Sbjct: 508  DNRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYTCECPKGYTGHDC 554



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 16/33 (48%), Positives = 16/33 (48%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            RC S PC NGA C D      C C  G TG  C
Sbjct: 1090 RCHSQPCQNGATCVDDDGVVFCKCAMGFTGTHC 1122



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      CSS+PC NG  C D  + + C C  G+ G  C
Sbjct: 668  CERDIDECSSSPCVNGGLCVDYTNYFECLCHPGYGGDRC 706



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTK---ASCEVDGDGSICRSGSQCVARR-EGGILCQ---- 1090
            +  F+CQCP+G TG  C T + +   + C+  G       G  C+ R    GI C+    
Sbjct: 158  INDFSCQCPQGITGQTCNTDIDECQSSPCKHQGTCQNYLGGFNCLCRHGYSGITCEVDVN 217

Query: 1091 GCSIDAAYTTAVC 1103
             CS        VC
Sbjct: 218  ECSSSPCVNGGVC 230



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 999  DNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE-T 1057
            D  C   P    E C T +    A    N+ +    P+     ++C CP G TG +C+ +
Sbjct: 958  DFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL---KGYSCSCPTGVTGRHCDVS 1014

Query: 1058 ILTKASCEVDGDGSICRSGSQCV 1080
            I     C  +G   + +SG QC+
Sbjct: 1015 ICDSKPCRNNGSCVLTQSGYQCL 1037



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 15/41 (36%), Positives = 19/41 (46%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C      C++ PC N   C D   +Y C CK G TG  C
Sbjct: 780  SNCETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRC 820



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 6/42 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV 1080
            V  F CQC  GF G NCET + +        G+ C +GS C+
Sbjct: 272  VDEFRCQCQPGFKGQNCETNINECI------GAACANGSTCI 307



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 14/39 (35%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      CS +PC +G  C DL   Y+C    G  G +C
Sbjct: 744  CEVNIDDCSPSPCRHGGSCQDLVTGYLCHWPAGFKGSNC 782



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 4/59 (6%)

Query: 1297 LNSYVA---DNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            LN Y     D  T   C +    C   PC+NG  C DL + Y C C +    + CA ++
Sbjct: 462  LNGYACLCIDGYTGLNCEKDIDDCLFNPCHNGT-CEDLVNNYKCVCPDNRQERTCAGNS 519



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 12/68 (17%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI-CRSGSQCVARREGGILCQGCSIDAA 1097
            V+ +TC C  GFTG+NC       S E+D  GS  C +   CV  R   + C  C++   
Sbjct: 880  VSGYTCLCMPGFTGINC-------SIEMDECGSYPCLNNGTCVDGR-NRVTCT-CAV--G 928

Query: 1098 YTTAVCEL 1105
            +T   CE+
Sbjct: 929  FTGQFCEV 936



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 14/39 (35%), Positives = 17/39 (43%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C S PC N   C D  +   C C  G TG+ C
Sbjct: 896  CSIEMDECGSYPCLNNGTCVDGRNRVTCTCAVGFTGQFC 934



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 46/188 (24%), Positives = 63/188 (33%), Gaps = 25/188 (13%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C   S C+    S  C C+ G  G  C   +  C   PC     C+       +
Sbjct: 332  ECQSNPCQHGSACMDGVSSYQCICQPGYTGQYCHIDIDECLSRPCLNNGMCL--DLVSDF 389

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC-NKENGK-CH-- 1627
             C C  G+  +   C  +  +        GS C     D+   Y   C     GK CH  
Sbjct: 390  HCTCPTGF--SGKDCSVNIDDCADAPCQHGSTC----IDLVNDYKCSCLQGYTGKDCHID 443

Query: 1628 ---CKENHYKPEGTAECL----PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
               C  N  +  GT   L     C C   G    +CE     C   P   G  C+   N 
Sbjct: 444  INECSSNPCQYGGTCLNLLNGYACLC-IDGYTGLNCEKDIDDCLFNPCHNG-TCEDLVNN 501

Query: 1681 YAEVTPNS 1688
            Y  V P++
Sbjct: 502  YKCVCPDN 509



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQ---CVARRE-GGILC 1089
            T +TC+CP+G+TG +CE+ +           + C  G+    C+  R   G LC
Sbjct: 539  TYYTCECPKGYTGHDCESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLC 592



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 13/33 (39%), Positives = 16/33 (48%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C+  PC  G  C D    Y C C  G TG +C+
Sbjct: 865  CTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCS 897



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG---SQCVARREGGILCQGCSID 1095
            V ++ C C  GFTG +C+  + +        GS C  G    QC+   + G   Q C ID
Sbjct: 310  VNAYQCTCLPGFTGRHCDVDIDECQSNPCQHGSACMDGVSSYQCIC--QPGYTGQYCHID 367



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 15/40 (37%), Positives = 17/40 (42%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDC 1348
            C      C + PC N A C  D    Y C C  G TG+ C
Sbjct: 972  CATPIDLCEAHPCQNNATCRMDPLKGYSCSCPTGVTGRHC 1011



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 11/35 (31%), Positives = 18/35 (51%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            F C C  G++G+ CE  + + S     +G +C  G
Sbjct: 199  FNCLCRHGYSGITCEVDVNECSSSPCVNGGVCADG 233



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 44/173 (25%), Positives = 54/173 (31%), Gaps = 24/173 (13%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQTPKGYS 1572
            DC+ + C     C    ++  C C   R    C    S C+   C             Y+
Sbjct: 484  DCLFNPCHN-GTCEDLVNNYKCVCPDNRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYT 542

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCAC-DVTRGYHPHCNKENGKCHCKEN 1631
            C C  GYT     C ES    C       S  G   C D    Y   C +      C  N
Sbjct: 543  CECPKGYT--GHDC-ESKINYCKSS----SCYGNATCLDGANNYTCICPRGFTGTLCDVN 595

Query: 1632 HYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYA 1682
                    EC    C    +  +SCE      +CHC  G  GR C    N  A
Sbjct: 596  ------VDECEDSPC----ANGASCEDLINDFRCHCPAGFQGRTCAVDINECA 638



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 13/78 (16%)

Query: 1009 NFEECLTVLKFGNASGFVNSDSVLFRPIYP-------VTSFTCQCPEGFTGVNCETILTK 1061
            N+ ECL    +G     +N D    +P          V  FTC C  G+TG  CE  +  
Sbjct: 691  NYFECLCHPGYGGDRCEINIDDCANKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNID- 749

Query: 1062 ASCEVDGDGSICRSGSQC 1079
                 D   S CR G  C
Sbjct: 750  -----DCSPSPCRHGGSC 762



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 6/39 (15%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079
            ++TC CP GFTG  C+  + +  CE     S C +G+ C
Sbjct: 578  NYTCICPRGFTGTLCDVNVDE--CE----DSPCANGASC 610



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 8/73 (10%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTK-ASCEVDGDGS-ICRSGS-QCVARRE-GGILCQG--- 1091
            VT + C  P GF G NCET + + A+   D +G+ + R  S  CV +    G  C+    
Sbjct: 766  VTGYLCHWPAGFKGSNCETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRCEANID 825

Query: 1092 -CSIDAAYTTAVC 1103
             C+       A+C
Sbjct: 826  DCATSPCLNNAIC 838


>SB_40912| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 634

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 1485 CIQDVRIGTAQSLLNRPTVRENVRD-GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGR 1543
            C QD+    +   LN  T  ++V    C    +C  + C   + C    +  TC+C+ G 
Sbjct: 195  CQQDINECQSNPCLNGATCTDHVNGYTCSYINECQSNPCLNGATCTDHVNGYTCSCKLGY 254

Query: 1544 VGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580
             G  C   ++ C+  PC       D    GY+C+C+ GYT
Sbjct: 255  TGIVCQQDINECQSNPCLNGATCTDHV-NGYTCSCKLGYT 293



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 10/69 (14%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD----------STGPPWRFG 1359
            C +  + C S PC NGA C+D  + Y C CK G+TG  C            ST P W   
Sbjct: 259  CQQDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVCQQVSSSQFLEPTSTTPQWALL 318

Query: 1360 GDGMLSFNP 1368
               M + NP
Sbjct: 319  STSMFTINP 327



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC NGA C+D  + Y C C  G+TG +C
Sbjct: 157  CETDINECQSNPCLNGATCTDHVNGYTCSCALGYTGIEC 195



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/34 (50%), Positives = 21/34 (61%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C S PC NGA C+D  + Y C CK G+TG  C
Sbjct: 226  NECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVC 259



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 1315 SRCSSAPCYNGAECSDLW--DTYICDCKEGHTGKDC 1348
            S C S PC +G+ C   +  DTY C C +G+TG+ C
Sbjct: 122  SPCQSDPCLHGSRCLATYTDDTYTCACLQGYTGRHC 157



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 16/112 (14%)

Query: 998  DDNICVHEPCLNFEECLTVLKFGNASGFVN---SDSVLFRPIYP--VTSFTCQCPEGFTG 1052
            D N C   PCLN   C   +  G    ++N   S+  L        V  +TC C  G+TG
Sbjct: 198  DINECQSNPCLNGATCTDHVN-GYTCSYINECQSNPCLNGATCTDHVNGYTCSCKLGYTG 256

Query: 1053 VNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
            + C+  + +  C+     + C +G+ C     G      CS    YT  VC+
Sbjct: 257  IVCQQDINE--CQ----SNPCLNGATCTDHVNG----YTCSCKLGYTGIVCQ 298



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 34/134 (25%), Positives = 49/134 (36%), Gaps = 11/134 (8%)

Query: 1550 SACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPC 1607
            S C+  PC   +RC+   T   Y+CAC  GY  T   C E+   EC       G+ C   
Sbjct: 122  SPCQSDPCLHGSRCLATYTDDTYTCACLQGY--TGRHC-ETDINECQSNPCLNGATC--- 175

Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667
              D   GY   C        C+++  + +    CL            +C +   +C   P
Sbjct: 176  -TDHVNGYTCSCALGYTGIECQQDINECQSN-PCLNGATCTDHVNGYTC-SYINECQSNP 232

Query: 1668 GVIGRACDACANAY 1681
             + G  C    N Y
Sbjct: 233  CLNGATCTDHVNGY 246



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 37/175 (21%), Positives = 66/175 (37%), Gaps = 11/175 (6%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICD---------CKEGHTGKDCADSTGPPWRFGG 1360
            C +  + C S PC NGA C+D  + Y C          C  G T  D  +      + G 
Sbjct: 195  CQQDINECQSNPCLNGATCTDHVNGYTCSYINECQSNPCLNGATCTDHVNGYTCSCKLGY 254

Query: 1361 DGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQL-KSGLLHYSYNGETMYLPMATLS 1419
             G++    +      P LN  +  T   + +  S +L  +G++    +      P +T  
Sbjct: 255  TGIVCQQDINECQSNPCLNGATC-TDHVNGYTCSCKLGYTGIVCQQVSSSQFLEPTSTTP 313

Query: 1420 DGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGL 1474
              A     +  +  +  +      RT ++ ++A K Q   + K+ +      AGL
Sbjct: 314  QWALLSTSMFTINPEEVMITSKFERTRVLNLIAGKFQLTKVHKLYVYTRQKRAGL 368



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 1037 YPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDA 1096
            Y   ++TC C +G+TG +CET + +  C+     + C +G+ C     G      CS   
Sbjct: 139  YTDDTYTCACLQGYTGRHCETDINE--CQ----SNPCLNGATCTDHVNG----YTCSCAL 188

Query: 1097 AYTTAVCE 1104
             YT   C+
Sbjct: 189  GYTGIECQ 196



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 4/62 (6%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TC+C  G  G +C   ++ C+  PC       D    GY+
Sbjct: 163  ECQSNPCLNGATCTDHVNGYTCSCALGYTGIECQQDINECQSNPCLNGATCTDHV-NGYT 221

Query: 1573 CA 1574
            C+
Sbjct: 222  CS 223


>SB_50709| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 953

 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 18/32 (56%), Positives = 23/32 (71%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C S PC NGA+C+++ D Y C CK G TGK+C
Sbjct: 581  CDSNPCNNGAQCNNMVDGYRCMCKSGFTGKNC 612



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            C  +   C++ PC NG  C D  + ++C C  G TG+ C  +T
Sbjct: 612  CEVEEDECTTNPCANGGACVDKINGFVCTCPSGFTGQFCEKAT 654



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 7/74 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA---CELGPC-GAARCVPD 1565
            C+   D C  + C     CV   +   CTC +G  G  C  A   C+ G C    +CV  
Sbjct: 612  CEVEEDECTTNPCANGGACVDKINGFVCTCPSGFTGQFCEKATVDCKPGACRNNGKCV-- 669

Query: 1566 QTPKGYSCACEPGY 1579
            + P G+ C C  GY
Sbjct: 670  EIPGGFQCLCSDGY 683



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 10/66 (15%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            V  + C C  GFTG NCE  + +  C  +     C +G  CV +  G +    C+  + +
Sbjct: 596  VDGYRCMCKSGFTGKNCE--VEEDECTTNP----CANGGACVDKINGFV----CTCPSGF 645

Query: 1099 TTAVCE 1104
            T   CE
Sbjct: 646  TGQFCE 651



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 18/67 (26%), Positives = 26/67 (38%), Gaps = 4/67 (5%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSC 1573
            C  + C   ++C    D   C C++G  G  C      C   PC       D+   G+ C
Sbjct: 581  CDSNPCNNGAQCNNMVDGYRCMCKSGFTGKNCEVEEDECTTNPCANGGACVDKI-NGFVC 639

Query: 1574 ACEPGYT 1580
             C  G+T
Sbjct: 640  TCPSGFT 646


>SB_22953| Best HMM Match : EGF_2 (HMM E-Value=1.3e-14)
          Length = 635

 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 48/201 (23%), Positives = 63/201 (31%), Gaps = 16/201 (7%)

Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGY 1571
            QS   C   IC              CTC  G  GP C  AC LG          +     
Sbjct: 90   QSGNSCPTPICSKGCAQGVCVKPDNCTCHPGYDGPSCDQACTLGRWDVNCNNTCECQNNS 149

Query: 1572 SCACEPGYTLTTSGCI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            +C    G    TSG   ++ +  C  G++G S    C C         CN   G C C  
Sbjct: 150  TCDSVQGICNCTSGWQGDACQLPCKSGYYGNSCKQVCQCQ----NRSRCNHVTGLCRCIS 205

Query: 1631 NHYKPEGTAEC------LPCQCYAAGSENSSCEAATGQC--HCRPGVIGRACD---ACAN 1679
                      C        C+        ++C+  TG+C   C  G  G  C    ACA+
Sbjct: 206  GWTGKRCERPCDSGYYGDECKRVCQCMNGATCDHVTGRCDQRCPVGTYGFDCAKVCACAD 265

Query: 1680 AYAEVTPNSGCEVVYDGCPRS 1700
                   +  C  +   C  S
Sbjct: 266  TEKCSVVSGECTCIAGSCSSS 286


>SB_3431| Best HMM Match : EGF (HMM E-Value=1.8e-08)
          Length = 480

 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 16/38 (42%), Positives = 25/38 (65%)

Query: 1311 PEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            P + + C S+PC NG  C+D  + Y C C+ G+TG++C
Sbjct: 191  PNEINECDSSPCKNGGNCTDQVNNYTCTCQPGYTGRNC 228



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 1/35 (2%)

Query: 1546 PQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580
            P  ++ C+  PC       DQ    Y+C C+PGYT
Sbjct: 191  PNEINECDSSPCKNGGNCTDQV-NNYTCTCQPGYT 224



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACEL 1554
            +C  S C     C    ++ TCTC+ G  G  C  AC +
Sbjct: 196  ECDSSPCKNGGNCTDQVNNYTCTCQPGYTGRNCEIACSV 234


>SB_12832| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1169

 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 64/250 (25%), Positives = 88/250 (35%), Gaps = 33/250 (13%)

Query: 1506 NVRDGCQSRADCMLSICPPYSKCVTSW--DSSTCTCEAGRVGPQCVSACELGPCGAARCV 1563
            N ++G  + A C  + CPP   C  S   D +   C AG   PQ        PC A    
Sbjct: 384  NSKNGSANNAAC--TSCPPGYYCQDSGLSDYTPYLCPAGHYCPQATKYSREFPCPAGTYN 441

Query: 1564 PDQTPKGYSCACE--PGYTLTTSGCIESGKEECPGGWW---GGSACGPCACDVTRGYHPH 1618
            PD      + AC+  P     T G +     +CP G++   G  A    AC    GY+  
Sbjct: 442  PDTNATTQTPACQTCPARKYCTRGSVTPA--DCPPGYYCPEGTRAGNQFACHA--GYYSD 497

Query: 1619 CNKENGKCHCKE---NHYKPEGT---AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGR 1672
                +    CK     +Y P+GT   A   P  C   G+ N        + +C     G 
Sbjct: 498  VTGLSNYTECKSCPPGYYCPDGTSQEATITPLPC-PIGTYNPEWNIGY-KINCVRCTAGM 555

Query: 1673 ACDACANAYAEVTPNSGCEVVYDG--CPRSFAGGVWWPRTKFGVETITDCPPGSSGRATR 1730
             C +     A         V Y+G  CP   A G  +P       T  D P  ++     
Sbjct: 556  FCPSAGQTNAS-------HVCYEGYYCPNGTAAGDQFPCPP---GTYGDRPGLTAAEECL 605

Query: 1731 TCDETKDVPW 1740
             C +TK   W
Sbjct: 606  RCPQTKSCGW 615



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 35/130 (26%), Positives = 48/130 (36%), Gaps = 14/130 (10%)

Query: 1522 CPPYSKCV--TSWDSSTCT--CEAGRVGPQCVSACELG--PCGAARCVPDQTPKGYSCAC 1575
            CPP   C   TS +++     C  G   P+     ++    C A    P       S  C
Sbjct: 510  CPPGYYCPDGTSQEATITPLPCPIGTYNPEWNIGYKINCVRCTAGMFCPSAGQTNASHVC 569

Query: 1576 EPGYTLTTSGCIESGKEECPGGWWGG----SACGPCA-CDVTR--GYHPHCNKENGKCHC 1628
              GY    +G     +  CP G +G     +A   C  C  T+  G+    N  N    C
Sbjct: 570  YEGY-YCPNGTAAGDQFPCPPGTYGDRPGLTAAEECLRCPQTKSCGWGTGLNNNNTWQDC 628

Query: 1629 KENHYKPEGT 1638
            +  HY PEGT
Sbjct: 629  RPGHYCPEGT 638


>SB_40516| Best HMM Match : Cadherin (HMM E-Value=0.042)
          Length = 126

 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 4/80 (5%)

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGG 663
           ATD+D G+NG + Y +     +   F I+P SG IRT     D++   +      A D G
Sbjct: 27  ATDSDTGINGVVEYRI---SEDTDLFYIEPTSGTIRTADIFADKDRGLSFSFMVQASDKG 83

Query: 664 TPPQSSTVIVHIKIEDINDS 683
           TPP+ +    HI I  + DS
Sbjct: 84  TPPKKTKENAHITIFLLRDS 103



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIRAQ 230
           A  KATD+D G N  + Y  I  +T + F I+  SG +       D ++  S+  +++A 
Sbjct: 23  AGTKATDSDTGINGVVEYR-ISEDTDL-FYIEPTSGTIRTADIFADKDRGLSFSFMVQAS 80

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           D G+P +       I I  + D+     TS
Sbjct: 81  DKGTPPKKTKENAHITIFLLRDSNSMVLTS 110



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 11/101 (10%)

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL-DRETMSGYLLTV 551
           ATDSD GIN  + Y +S +            F I P +G I T  +  D++    +   V
Sbjct: 27  ATDSDTGINGVVEYRISED---------TDLFYIEPTSGTIRTADIFADKDRGLSFSFMV 77

Query: 552 TARDGGVPSLSDTTDVEISVVDVND-NEPVFKQQLYTANIM 591
            A D G P      +  I++  + D N  V   ++   +I+
Sbjct: 78  QASDKGTPPKKTKENAHITIFLLRDSNSMVLTSKMSKEDIL 118



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL-DRETQAKY 332
           Y     +A D+D G+N  + Y +++     + DL   I+P SG + T+    D++    +
Sbjct: 20  YLAAGTKATDSDTGINGVVEYRISE-----DTDL-FYIEPTSGTIRTADIFADKDRGLSF 73

Query: 333 QLLVTATDGGDPPR 346
             +V A+D G PP+
Sbjct: 74  SFMVQASDKGTPPK 87


>SB_23966| Best HMM Match : EGF (HMM E-Value=2.4e-40)
          Length = 167

 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 9/98 (9%)

Query: 1487 QDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGP 1546
            +D+  GTA+ ++      +NVR    +  +C  + C   +KC    +  TC C  G  G 
Sbjct: 30   KDILEGTARRVIFD---EKNVRKLINNINECQSNPCLNGAKCNDHVNGYTCKCAPGYTGI 86

Query: 1547 QC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
             C   ++ C+  PC   A C  +    GY+C C PGYT
Sbjct: 87   VCQQDINECQSNPCLNGATC--NDHVNGYTCKCAPGYT 122



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C S PC NGA C+D  + Y C C  G+TG  C
Sbjct: 88   CQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVC 126



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C S PC NGA C+D  + Y C C  G+TG  C
Sbjct: 126  CQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVC 164



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 16/34 (47%), Positives = 21/34 (61%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C S PC NGA+C+D  + Y C C  G+TG  C
Sbjct: 55   NECQSNPCLNGAKCNDHVNGYTCKCAPGYTGIVC 88



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C   + C    +  TC C  G  G  C   ++ C+  PC   A C  +    GY
Sbjct: 94   ECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVCQQDINECQSNPCLNGATC--NDHVNGY 151

Query: 1572 SCACEPGYT 1580
            +C C PGYT
Sbjct: 152  TCKCAPGYT 160



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 17/127 (13%)

Query: 1549 VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPC 1607
            ++ C+  PC   A+C  +    GY+C C PGYT     C +   E        G+ C   
Sbjct: 54   INECQSNPCLNGAKC--NDHVNGYTCKCAPGYTGIV--CQQDINECQSNPCLNGATCN-- 107

Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667
              D   GY   C        C+++        EC    C    + N      T  C C P
Sbjct: 108  --DHVNGYTCKCAPGYTGIVCQQD------INECQSNPCLNGATCNDHVNGYT--CKCAP 157

Query: 1668 GVIGRAC 1674
            G  G  C
Sbjct: 158  GYTGIVC 164



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 4/56 (7%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQC-VARREGGILCQ 1090
            V  +TC+C  G+TG+ C+  + +       +G+ C    +G  C  A    GI+CQ
Sbjct: 72   VNGYTCKCAPGYTGIVCQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVCQ 127



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 4/56 (7%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQC-VARREGGILCQ 1090
            V  +TC+C  G+TG+ C+  + +       +G+ C    +G  C  A    GI+CQ
Sbjct: 110  VNGYTCKCAPGYTGIVCQQDINECQSNPCLNGATCNDHVNGYTCKCAPGYTGIVCQ 165


>SB_16748| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 280

 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC NGA C+D  ++Y C CK G TG +C
Sbjct: 239  CDNDIDECASNPCQNGATCNDGVNSYTCSCKPGFTGTNC 277



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 39/142 (27%), Positives = 53/142 (37%), Gaps = 18/142 (12%)

Query: 1537 CTCEAGRVGPQCVS---ACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593
            C C  G  G +C +    C+  PC  +    D+   GY+CAC PG+  T   C E+   E
Sbjct: 152  CLCPEGFSGDKCENHDNECQSSPCKNSGTCKDED-NGYTCACVPGF--TDKNC-ETDINE 207

Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653
            C G      A G    D   G+   C        C  +        EC    C    + N
Sbjct: 208  CAG---DPCANGGTCTDGINGFTCTCPAGYNGSTCDND------IDECASNPCQNGATCN 258

Query: 1654 SSCEAATGQCHCRPGVIGRACD 1675
                + T  C C+PG  G  C+
Sbjct: 259  DGVNSYT--CSCKPGFTGTNCE 278



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 6/71 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C    C     C    +  TCTC AG  G  C   +  C   PC   A C  +     Y
Sbjct: 207  ECAGDPCANGGTCTDGINGFTCTCPAGYNGSTCDNDIDECASNPCQNGATC--NDGVNSY 264

Query: 1572 SCACEPGYTLT 1582
            +C+C+PG+T T
Sbjct: 265  TCSCKPGFTGT 275



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 7/64 (10%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362
            C    + C S+PC N   C D  + Y C C  G T K+C     +  G P   GG   DG
Sbjct: 163  CENHDNECQSSPCKNSGTCKDEDNGYTCACVPGFTDKNCETDINECAGDPCANGGTCTDG 222

Query: 1363 MLSF 1366
            +  F
Sbjct: 223  INGF 226



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+  PC NG  C+D  + + C C  G+ G  C
Sbjct: 201  CETDINECAGDPCANGGTCTDGINGFTCTCPAGYNGSTC 239



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 26/113 (23%), Positives = 37/113 (32%), Gaps = 7/113 (6%)

Query: 1509 DGCQSRA-DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVP 1564
            D C++   +C  S C     C    +  TC C  G     C   ++ C   PC       
Sbjct: 161  DKCENHDNECQSSPCKNSGTCKDEDNGYTCACVPGFTDKNCETDINECAGDPCANGGTCT 220

Query: 1565 DQTPKGYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615
            D    G++C C  GY  +T  +   E     C  G           C    G+
Sbjct: 221  DGI-NGFTCTCPAGYNGSTCDNDIDECASNPCQNGATCNDGVNSYTCSCKPGF 272



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 13/19 (68%), Positives = 14/19 (73%)

Query: 1039 VTSFTCQCPEGFTGVNCET 1057
            V S+TC C  GFTG NCET
Sbjct: 261  VNSYTCSCKPGFTGTNCET 279



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC C  GFT  NCET + + +      G  C +G  C      GI    C+  A Y  +
Sbjct: 188  YTCACVPGFTDKNCETDINECA------GDPCANGGTCT----DGINGFTCTCPAGYNGS 237

Query: 1102 VCE 1104
             C+
Sbjct: 238  TCD 240



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 11/38 (28%), Positives = 19/38 (50%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            +  FTC CP G+ G  C+  + + +     +G+ C  G
Sbjct: 223  INGFTCTCPAGYNGSTCDNDIDECASNPCQNGATCNDG 260


>SB_3457| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 848

 Score = 48.4 bits (110), Expect = 8e-05
 Identities = 51/186 (27%), Positives = 67/186 (36%), Gaps = 21/186 (11%)

Query: 1508 RDGCQSRADCMLSICPPYSKCV-TSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARC 1562
            RD  +  + C  S C   + C+ T  DS  C C     G  C   +  C+  PC     C
Sbjct: 528  RDCGERVSSCESSPCENGATCIETDHDSFRCECTDKYGGHLCRDIIDPCQRNPCLNGGHC 587

Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWW-GGSACGPCACDVTRGYHPHCNK 1621
                    Y CAC  GY+ TT  C  +   EC       G   G C C    GY+     
Sbjct: 588  T--SAGDSYKCACNEGYSGTT--CEVTLHTECMDCHVNAGCTDGKCVCH--SGYY----- 636

Query: 1622 ENGKCHCKENHYKP-EGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
             NG  HC+     P +  + CL   C   G+     E    +C C  G  G  C+  A  
Sbjct: 637  GNGH-HCEPLPAAPTKPPSPCLSNPCRHGGT--CMDEGGKFRCVCADGYKGELCEKKAQH 693

Query: 1681 YAEVTP 1686
            +    P
Sbjct: 694  FCHPNP 699



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDL-WDTYICDCKEGHTGKDCADSTGP 1354
            C E+ S C S+PC NGA C +   D++ C+C + + G  C D   P
Sbjct: 530  CGERVSSCESSPCENGATCIETDHDSFRCECTDKYGGHLCRDIIDP 575



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    C   PC NG  C+   D+Y C C EG++G  C
Sbjct: 569  CRDIIDPCQRNPCLNGGHCTSAGDSYKCACNEGYSGTTC 607



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 1315 SRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADS 1351
            ++C   PC NGA C +  D+  Y C CK G  G +C ++
Sbjct: 457  NKCLPNPCKNGAMCVEHGDSTEYSCICKSGFKGSNCEEA 495



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 6/49 (12%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQ 1090
            F C+CP GFTG +C   +  +SCE     S C +G+ C+        C+
Sbjct: 517  FVCRCPAGFTGRDCGERV--SSCE----SSPCENGATCIETDHDSFRCE 559



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 13/42 (30%), Positives = 17/42 (40%)

Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355
            R++C   PC N   C+     Y C C  G  G+ C      P
Sbjct: 294  RAKCEPNPCLNDGVCTAFLHDYECACPAGFMGRHCEGKVSNP 335



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 1322 CYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C NG  C +    ++C C  G TG+DC +
Sbjct: 504  CKNGGTCMNGQQMFVCRCPAGFTGRDCGE 532



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 1307 LAGCPEKR-SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            L   P K  S C S PC +G  C D    + C C +G+ G+ C
Sbjct: 645  LPAAPTKPPSPCLSNPCRHGGTCMDEGGKFRCVCADGYKGELC 687



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSR-CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +K    C   PC +G  C +  D Y C C   + G+ C
Sbjct: 687  CEKKAQHFCHPNPCLHGGTCDEKEDGYTCRCIGAYRGEHC 726


>SB_52148| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1055

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 43/162 (26%), Positives = 61/162 (37%), Gaps = 25/162 (15%)

Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTL 1581
            +  CVT  D+  C C+ G  G +C   +  C+L PC         T +G+ C C+ GY  
Sbjct: 855  HGHCVTRRDALFCQCDFGYYGAECDRRMDYCKLKPCVVENGWCVNTQQGFRCVCKRGY-- 912

Query: 1582 TTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG----KC-----HCKEN- 1631
               G     K  C         C P    +TR   P C    G    +C     HC  N 
Sbjct: 913  --GGLRCHKKNACL-----PDPCAPHGICMTRRGDPFCVCTEGYTGLRCKVVINHCLSNP 965

Query: 1632 --HYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIG 1671
              +     T+    C+C   G + + CE A   C+  P + G
Sbjct: 966  CLNGVCVSTSSTYTCRC-TVGFKGTRCEHAMNTCYSNPCIHG 1006



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 48/171 (28%), Positives = 62/171 (36%), Gaps = 29/171 (16%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQT 1567
            C +   CM   C  +  CV+S     C C AG +G  C     CE  PC     C   ++
Sbjct: 769  CTTADPCMRLACV-HGACVSSNGVVRCECSAGYLGKSCNMTDPCEPSPCLNGGSCT--KS 825

Query: 1568 PKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC--NKENGK 1625
               +SC C PGY     G   S  + C      G A  PC        H HC   ++   
Sbjct: 826  GLAHSCECTPGY----EGANCSITKRC------GDA--PCR-------HGHCVTRRDALF 866

Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSC-EAATG-QCHCRPGVIGRAC 1674
            C C   +Y  E       C+      EN  C     G +C C+ G  G  C
Sbjct: 867  CQCDFGYYGAECDRRMDYCKLKPCVVENGWCVNTQQGFRCVCKRGYGGLRC 917



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 5/72 (6%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQT 1567
            C  +  C+   C P+  C+T      C C  G  G +C   ++ C   PC    CV   T
Sbjct: 917  CHKKNACLPDPCAPHGICMTRRGDPFCVCTEGYTGLRCKVVINHCLSNPCLNGVCV--ST 974

Query: 1568 PKGYSCACEPGY 1579
               Y+C C  G+
Sbjct: 975  SSTYTCRCTVGF 986



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 38/134 (28%), Positives = 48/134 (35%), Gaps = 18/134 (13%)

Query: 1520 SICPPYS----KCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            S C P S    +CV +  +S+C C  G  G  C   +SACE  PC    C+  +    Y 
Sbjct: 347  SACKPTSCVNGECVGNGHNSSCKCWKGYSGASCDVKISACEHRPCVQGVCIGRENFTLYH 406

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632
            C     Y  T   C E     C    W     G C    + G H  C    G    +  H
Sbjct: 407  CKWNRLY--TGRNC-EIKLSLCA---WDSCGFGECV-KTSNGTHWRCVGHVGNTGERFEH 459

Query: 1633 Y----KPEGTAECL 1642
            Y     P G   C+
Sbjct: 460  YMCASTPRGNRTCM 473



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 4/40 (10%)

Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDCADSTGPP 1355
            C S PC  G  C +L   TY+C CKEG TG  C   TG P
Sbjct: 274  CQSNPCGRGL-CKELTRTTYMCICKEGFTGTHC--ETGTP 310



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 5/56 (8%)

Query: 1528 CVTSWDSSTCTCEAGRVGPQCV---SACELGPCGAARCVPDQTPKGYSCACEPGYT 1580
            C  S  S TC C +G  GP C    SAC+   C    CV +      SC C  GY+
Sbjct: 322  CTESNSSFTCECFSGYTGPTCAVVESACKPTSCVNGECVGN--GHNSSCKCWKGYS 375



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 42/162 (25%), Positives = 51/162 (31%), Gaps = 32/162 (19%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACE 1576
            C  S C  +  C+ + D   C     R   Q +  CE  PC    C P      ++C C 
Sbjct: 709  CQFSHCI-HGNCMVTLDGHRCA----RCSEQAMDPCESNPCVHGTCRPRN--DSFTCQCF 761

Query: 1577 PGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCKENHY- 1633
             GY          G+  C         C   AC      H  C   NG  +C C   +  
Sbjct: 762  EGYI---------GR-LCT----TADPCMRLAC-----VHGACVSSNGVVRCECSAGYLG 802

Query: 1634 -KPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
                 T  C P  C   GS   S       C C PG  G  C
Sbjct: 803  KSCNMTDPCEPSPCLNGGSCTKS--GLAHSCECTPGYEGANC 842



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 11/33 (33%), Positives = 18/33 (54%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C  +PC NG  C+     + C+C  G+ G +C+
Sbjct: 811  CEPSPCLNGGSCTKSGLAHSCECTPGYEGANCS 843



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C   PC NG  C++   ++ C+C  G+TG  CA
Sbjct: 305  CETGTPLCLPNPCING-NCTESNSSFTCECFSGYTGPTCA 343



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 8/84 (9%)

Query: 1537 CTCEAGRVGPQCVSA---CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESG--K 1591
            C C+ G  G  C +    C   PC    C   ++   ++C C  GYT  T   +ES    
Sbjct: 294  CICKEGFTGTHCETGTPLCLPNPCINGNCT--ESNSSFTCECFSGYTGPTCAVVESACKP 351

Query: 1592 EECPGGWWGGSACGPCACDVTRGY 1615
              C  G   G+     +C   +GY
Sbjct: 352  TSCVNGECVGNGHN-SSCKCWKGY 374



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)

Query: 1303 DNGTLAGCPEKR-SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            D    A C E+    C S PC +G  C    D++ C C EG+ G+ C
Sbjct: 724  DGHRCARCSEQAMDPCESNPCVHGT-CRPRNDSFTCQCFEGYIGRLC 769



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 12/64 (18%)

Query: 1043 TCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAV 1102
            +C+C  G+ G NC   +TK  C   GD   CR G  CV RR+  + CQ C  D  Y  A 
Sbjct: 830  SCECTPGYEGANCS--ITK-RC---GDAP-CRHG-HCVTRRD-ALFCQ-C--DFGYYGAE 877

Query: 1103 CELR 1106
            C+ R
Sbjct: 878  CDRR 881



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 11/18 (61%), Positives = 14/18 (77%)

Query: 1040 TSFTCQCPEGFTGVNCET 1057
            T++ C C EGFTG +CET
Sbjct: 290  TTYMCICKEGFTGTHCET 307



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 15/39 (38%), Positives = 16/39 (41%), Gaps = 1/39 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC NG  C     TY C C  G  G  C
Sbjct: 954  CKVVINHCLSNPCLNGV-CVSTSSTYTCRCTVGFKGTRC 991


>SB_48268| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 4527

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 48/173 (27%), Positives = 61/173 (35%), Gaps = 29/173 (16%)

Query: 1522 CPPY-SKCVTSWDSSTCTCEAGRVGP--QCVSACELGPCGAARCVPD-----QTPKGYSC 1573
            C P  S C  +  S TC+C AG  G    CV   +    GA  C P       T   Y+C
Sbjct: 604  CAPIGSSCTNNAGSYTCSCNAGYAGDGETCVEDIDECSSGAHTCAPSGSTCTNTVGSYTC 663

Query: 1574 ACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHY 1633
            AC  GYT     C++   +EC     G   C P     T          +  C C    Y
Sbjct: 664  ACNVGYTGDGETCVDI--DECSA---GSHTCAPSVSTCTN------TVGSFTCACNAG-Y 711

Query: 1634 KPEGTA-----ECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIGRACDACAN 1679
              +G A     EC     +      S+C    G   C C  G  G   + CA+
Sbjct: 712  TGDGEACTDIDECTD-GVHTCALNGSTCTNTVGSYTCACNAGYTGNG-ETCAD 762



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 42/164 (25%), Positives = 59/164 (35%), Gaps = 23/164 (14%)

Query: 1521 ICPPY-SKCVTSWDSSTCTCEAGRVGPQCVSACELGPC--GAARCVP-----DQTPKGYS 1572
            +C P  S C  +  + TC C AG  G   V+  ++  C  G   C P           Y+
Sbjct: 561  LCAPSGSTCTNTVGAFTCACNAGYTG-DGVTCTDIDECSDGTNTCAPIGSSCTNNAGSYT 619

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632
            C+C  GY      C+E   +EC     G   C P     T     +       C C    
Sbjct: 620  CSCNAGYAGDGETCVED-IDECSS---GAHTCAPSGSTCTNTVGSY------TCACNVG- 668

Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA 1676
            Y  +G   C+     +AGS   +C  +   C    G    AC+A
Sbjct: 669  YTGDGET-CVDIDECSAGSH--TCAPSVSTCTNTVGSFTCACNA 709



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 1547 QCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606
            +C +A    PC    CV   T  GY C C PGY L +   I S  +EC     G   C P
Sbjct: 467  ECSAAALHPPCDTL-CVVADTDSGYQCLCNPGYHLDSDPHICSDIDECTS---GSHTCAP 522

Query: 1607 C--ACDVTRGYHPHCNKENG 1624
                C  T G +  C  ++G
Sbjct: 523  SGGVCTNTMGSYT-CACDSG 541



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 38/158 (24%), Positives = 54/158 (34%), Gaps = 17/158 (10%)

Query: 1523 PPYSKCVTSWDSSTCTCEAGRVGPQ--C--VSACELGP--CGAARCVPDQTPKGYSCACE 1576
            P    C  +  S TC C++G  G    C  +  C  G   C  +      T   ++CAC 
Sbjct: 522  PSGGVCTNTMGSYTCACDSGYTGDGQICTDIDECSSGGHLCAPSGSTCTNTVGAFTCACN 581

Query: 1577 PGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKCHCKENHYKP 1635
             GYT     C +   +EC     G + C P     T     + C+   G  +  +     
Sbjct: 582  AGYTGDGVTCTDI--DECSD---GTNTCAPIGSSCTNNAGSYTCSCNAG--YAGDGETCV 634

Query: 1636 EGTAECLPCQCYAAGSENSSCEAATGQ--CHCRPGVIG 1671
            E   EC     +      S+C    G   C C  G  G
Sbjct: 635  EDIDEC-SSGAHTCAPSGSTCTNTVGSYTCACNVGYTG 671



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 35/110 (31%), Positives = 43/110 (39%), Gaps = 13/110 (11%)

Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP--CACDVTRG 1614
            C  +  V   T   Y+CAC+ GY  T  G I +  +EC     GG  C P    C  T G
Sbjct: 520  CAPSGGVCTNTMGSYTCACDSGY--TGDGQICTDIDECSS---GGHLCAPSGSTCTNTVG 574

Query: 1615 -YHPHCNK--ENGKCHCKENHYKPEGTAECLP--CQC-YAAGSENSSCEA 1658
             +   CN         C +     +GT  C P    C   AGS   SC A
Sbjct: 575  AFTCACNAGYTGDGVTCTDIDECSDGTNTCAPIGSSCTNNAGSYTCSCNA 624



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 4/55 (7%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093
            V S+TC C  G+TG N ET      C V G  +   SGS C     G  +C  CS
Sbjct: 742  VGSYTCACNAGYTG-NGETCADIDECSV-GSHTCAPSGSTC-TNNVGSYVCT-CS 792


>SB_42006| Best HMM Match : EGF_2 (HMM E-Value=8.7e-05)
          Length = 326

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 52/178 (29%), Positives = 68/178 (38%), Gaps = 37/178 (20%)

Query: 1518 MLSICPPYSKCVTSWD----SSTCTCEAGRV-----GP---QCV---------SACELGP 1556
            +LS+C PY++C    D    + TC C    V     GP   +C          S C+ G 
Sbjct: 50   VLSLCDPYTQCFGHGDYNAATQTCKCYTAAVINVHWGPYTGECCESIGCTNPNSTCKHGA 109

Query: 1557 CG--AARCVPDQTP-KGYSC----ACEPGYTLTTSGCIESG-KEECPGGWWGGSACGPCA 1608
            C      C   QT   G +C    AC P        C +S  + EC  G W G  C    
Sbjct: 110  CAIDGTSCERCQTGWTGANCDNVTACFPWLACAHGRCTKSRFRCECDPG-WHGDLCDRAM 168

Query: 1609 CDVTRGYHPHCNKENGKCHCKENHYKPE------GTAECLPCQCYAAGSENSSCEAAT 1660
            C+V   +   C  +  KC C  N+Y PE       T   LP   +A  S N+   A T
Sbjct: 169  CNVPCHFGA-CPHDPNKCECYSNYYSPETGCDRLATPASLPVGAHALRSGNALSHACT 225


>SB_21404| Best HMM Match : VWA (HMM E-Value=8.1e-27)
          Length = 267

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    CSS+PC NGA C      Y C+C   H GK+C
Sbjct: 38   CTDDVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 76



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 2/36 (5%)

Query: 1317 CSSAPCYNGAECSDL--WDTYICDCKEGHTGKDCAD 1350
            C S PC NG  CS +     Y C C  G+TGK+C D
Sbjct: 5    CLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTD 40



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%)

Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093
            PI   + +TC C  G+TG NC   + + S       S C++G+ C+ ++ G   C+ CS
Sbjct: 18   PISSGSDYTCACAAGYTGKNCTDDVDECS------SSPCQNGASCI-KKVGRYFCE-CS 68



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 8/69 (11%)

Query: 1517 CMLSICPPYSKC--VTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570
            C+   C     C  ++S    TC C AG  G  C   V  C   PC   A C+  +    
Sbjct: 5    CLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTDDVDECSSSPCQNGASCI--KKVGR 62

Query: 1571 YSCACEPGY 1579
            Y C C   +
Sbjct: 63   YFCECSTAH 71


>SB_41690| Best HMM Match : DSL (HMM E-Value=0)
          Length = 2798

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 41/164 (25%), Positives = 61/164 (37%), Gaps = 13/164 (7%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G + C   W+G +    C   ++   H  C+   GK HC  + Y    TA C P     
Sbjct: 1059 TGSKICHSNWYGENCTVYCKAQLSDHQHYICDNTTGKKHCLTSWYGENCTAYCTPRN--- 1115

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWP 1708
              + + SC   TG   C  G  G  C    + Y    P++G    YD C  S +G     
Sbjct: 1116 DSTGHFSCNETTGSKDCHDGWYGGTC----SIYC--LPHNGSSGHYD-CDAS-SGRKTCH 1167

Query: 1709 RTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMF--NCTT 1750
               +G+     C      +    C+ T        D++  NCTT
Sbjct: 1168 VDWYGINCTVFCSKPRDSKDHYYCNVTNGEKVCTEDLYGRNCTT 1211



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 43/173 (24%), Positives = 63/173 (36%), Gaps = 18/173 (10%)

Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGY 1579
            +C  Y  C+ + DSS   +C A   G +   A   G      C+P     G+       Y
Sbjct: 515  LCDTY--CIPTIDSSGHYSCNA-TTGEKICHAGWYGRLCDTYCIPTNDSSGH-------Y 564

Query: 1580 TLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTA 1639
            T  T+    +G++ C  GW+G      C        H  CN   G+  C    Y      
Sbjct: 565  TCNTT----TGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNASTGEMICHAGWYGNLCDI 620

Query: 1640 ECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692
             C+P       S + SC   TG+  C  G  G  CD       +++ +  C V
Sbjct: 621  YCIPTD---DSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDISGHYSCNV 670



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 45/158 (28%), Positives = 60/158 (37%), Gaps = 20/158 (12%)

Query: 1520 SICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG-YSCACEP 1577
            ++C  Y  C+++ DSS   TC A   G +   A   G      C+P     G YSC    
Sbjct: 310  NLCDTY--CISTNDSSGHYTCNA-TTGEKICHAGWYGRLCDTYCIPTNDSSGHYSC---- 362

Query: 1578 GYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEG 1637
               +TT      G++ C  GW+G      C        H  CN   G+  C    Y    
Sbjct: 363  --NVTT------GEKICHAGWYGNLCDIYCIPTNDSSGHYSCNTTTGEKICHAGWYGNLC 414

Query: 1638 TAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
               C+P       S + SC   TG+  C  G  GR CD
Sbjct: 415  DIYCIPTNDI---SGHYSCNVTTGEKICHAGWYGRLCD 449



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 3/89 (3%)

Query: 1587 IESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQC 1646
            + +G++ C  GW+G      C        H  CN   G+  C    Y       C+P   
Sbjct: 772  VTTGEKICHAGWYGNLCDIYCIPTNDSSGHYSCNATTGEKICHAGWYGRLCDIYCIPTN- 830

Query: 1647 YAAGSENSSCEAATGQCHCRPGVIGRACD 1675
                S + SC A+TG+  C  G  GR CD
Sbjct: 831  --DSSGHYSCNASTGEMICHAGWYGRLCD 857



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G++ C  GW+G      C        H  CN   G+  C    Y       C+P     
Sbjct: 808  TGEKICHAGWYGRLCDIYCIPTNDSSGHYSCNASTGEMICHAGWYGRLCDTYCIPTN--- 864

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACD 1675
              S + SC A+TG+  C  G  GR CD
Sbjct: 865  DSSGHYSCNASTGEMICHAGWYGRLCD 891



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 14/94 (14%)

Query: 1586 CIESGKEECPGGWWG---GSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECL 1642
            C   G + C  GW+G   G  C P   D     H  CN+  G+  C ++ +   GT    
Sbjct: 230  CDSKGNKVCRRGWYGPLNGCLCRPRNSD---SGHYTCNRTTGEKICLKSWF---GTL--- 280

Query: 1643 PCQCYAAGSE-NSSCEAATGQCHCRPGVIGRACD 1675
             C  Y   S+ N SC A TG+  C  G  G  CD
Sbjct: 281  -CTIYCDESKGNYSCNATTGEKICHAGWYGNLCD 313



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 26/106 (24%), Positives = 39/106 (36%), Gaps = 3/106 (2%)

Query: 1587 IESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQC 1646
            + +G++ C  GW+G      C        H  CN   G+  C    Y       C+P   
Sbjct: 670  VTTGEKICHAGWYGNLCDIYCIPTNDSSGHYSCNATTGEKICHAGWYGNLCDIYCIPTN- 728

Query: 1647 YAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692
                S + SC   TG+  C  G  G  CD       +++ +  C V
Sbjct: 729  --DSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDISGHYSCNV 772



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 43/157 (27%), Positives = 57/157 (36%), Gaps = 20/157 (12%)

Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG-YSCACEPG 1578
            +C  Y  C+ + DSS   +C A   G +   A   G      C+P     G YSC     
Sbjct: 447  LCDIY--CIPTNDSSGHYSCNA-TTGEKICHAGWYGNLCDIYCIPTNDSSGHYSC----- 498

Query: 1579 YTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638
               TT      G++ C  GW G      C   +    H  CN   G+  C    Y     
Sbjct: 499  -NATT------GEKVCHVGWHGKLCDTYCIPTIDSSGHYSCNATTGEKICHAGWYGRLCD 551

Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
              C+P       S + +C   TG+  C  G  GR CD
Sbjct: 552  TYCIPTN---DSSGHYTCNTTTGEKICHAGWYGRLCD 585



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G++ C  GW+G      C        H  CN   G+  C    Y       C+P     
Sbjct: 298  TGEKICHAGWYGNLCDTYCISTNDSSGHYTCNATTGEKICHAGWYGRLCDTYCIPTN--- 354

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACD 1675
              S + SC   TG+  C  G  G  CD
Sbjct: 355  DSSGHYSCNVTTGEKICHAGWYGNLCD 381



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 26/104 (25%), Positives = 38/104 (36%), Gaps = 3/104 (2%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G++ C  GW+G      C        H  CN   G+  C    Y       C+P     
Sbjct: 332  TGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNVTTGEKICHAGWYGNLCDIYCIPTN--- 388

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692
              S + SC   TG+  C  G  G  CD       +++ +  C V
Sbjct: 389  DSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDISGHYSCNV 432



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 41/157 (26%), Positives = 52/157 (33%), Gaps = 20/157 (12%)

Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG-YSCACEPG 1578
            +C  Y  C+ + DSS   TC     G +   A   G      C+P     G YSC    G
Sbjct: 549  LCDTY--CIPTNDSSGHYTCNT-TTGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNASTG 605

Query: 1579 YTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGT 1638
              +            C  GW+G      C        H  CN   G+  C    Y     
Sbjct: 606  EMI------------CHAGWYGNLCDIYCIPTDDSSGHYSCNTTTGEKICHAGWYGNLCD 653

Query: 1639 AECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
              C+P       S + SC   TG+  C  G  G  CD
Sbjct: 654  IYCIPTNDI---SGHYSCNVTTGEKICHAGWYGNLCD 687



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G++ C  GW+G      C        H  CN   G+  C    Y       C+P     
Sbjct: 706  TGEKICHAGWYGNLCDIYCIPTNDSSGHYSCNTTTGEKICHAGWYGNLCDIYCIPTNDI- 764

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACD 1675
              S + SC   TG+  C  G  G  CD
Sbjct: 765  --SGHYSCNVTTGEKICHAGWYGNLCD 789



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 23/101 (22%), Positives = 39/101 (38%), Gaps = 2/101 (1%)

Query: 1586 CIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ 1645
            C + G + C   W+G +    C  + +      C+   G   C  + Y  E    C+P  
Sbjct: 2309 CDDKGNKICLSNWYGLACNRFCKAENSTLRSYTCDNTTGLKICSTHWYGSECHTYCIPRA 2368

Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686
             +  G    +C   TG   C PG  G  C +  ++ + + P
Sbjct: 2369 SHLEGY--FTCNETTGTRICIPGWTGNNCTSSKHSQSSIFP 2407



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 22/102 (21%), Positives = 38/102 (37%), Gaps = 3/102 (2%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G + C   W+G +    C    +   +  C+   G   C  N Y    T   + C+   
Sbjct: 1025 TGSKLCHPDWFGENCTVHCKAQSSDNQNYSCDNATGSKICHSNWYGENCT---VYCKAQL 1081

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
            +  ++  C+  TG+ HC     G  C A      + T +  C
Sbjct: 1082 SDHQHYICDNTTGKKHCLTSWYGENCTAYCTPRNDSTGHFSC 1123



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G++ C   W+G + C    CD ++G +  CN   G+  C    Y       C+      
Sbjct: 267  TGEKICLKSWFG-TLC-TIYCDESKGNYS-CNATTGEKICHAGWYGNLCDTYCISTN--- 320

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEV 1692
              S + +C A TG+  C  G  GR CD       + + +  C V
Sbjct: 321  DSSGHYTCNATTGEKICHAGWYGRLCDTYCIPTNDSSGHYSCNV 364



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 39/153 (25%), Positives = 57/153 (37%), Gaps = 13/153 (8%)

Query: 1528 CVTSWDSSTCT--CEA--GRVGPQCVSACELGPCGAARCVPDQTPKGYSCAC-EPGYTLT 1582
            C+ +W    C+  CE    + GP     C+    G   C+P+      S  C E G    
Sbjct: 2012 CLPNWYGVNCSKYCEEKDDKFGPY---RCD-NSTGEKICLPNWYGVNCSKYCKEKGDNSG 2067

Query: 1583 TSGCIES-GKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
               C  S G++ C   W+G +    C        +  C+   G+  C  N Y   GT   
Sbjct: 2068 NYRCDNSTGEKICLPNWYGVNCSKYCKEKDDNSGNYRCDNSTGEKICLPNWY---GTNCI 2124

Query: 1642 LPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
              C+     S N  C+ +TG+  C P   G  C
Sbjct: 2125 KYCKEKGDNSGNYRCDNSTGEKICLPNWYGTNC 2157



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 26/103 (25%), Positives = 39/103 (37%), Gaps = 3/103 (2%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G++ C   W+G +    C        +  C+   GK  C  N Y   GT     C+   
Sbjct: 2143 TGEKICLPNWYGTNCIKYCKEKDDNSGNYRCDNSTGKKICLPNWY---GTNCIKYCKEKG 2199

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691
              S N  C+ +TG+  C P   G  C        + + N  CE
Sbjct: 2200 DNSGNYRCDNSTGEKICLPNWYGVNCSKYCKEKDDNSGNYRCE 2242



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 16/53 (30%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C +N Y    T  C
Sbjct: 1467 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDNWYGGNCTTYC 1519



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 38/163 (23%), Positives = 57/163 (34%), Gaps = 14/163 (8%)

Query: 1539 CEAGRVGPQCVSACELGPCGAARC-------VPDQTPKGYSCA--CEPGYTLTTSGCIES 1589
            C     G  C   C+    G  RC       +  Q   G +C+  CE            S
Sbjct: 1948 CHKNWYGKNCRKHCQTSTRGNYRCDNVTGDKICTQKWYGENCSVFCEQNAGSHYKCNNGS 2007

Query: 1590 GKEECPGGWWGGSACGPCACDVTRGYHPH-CNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            GK+ C   W+G +    C  +    + P+ C+   G+  C  N Y   G      C+   
Sbjct: 2008 GKKICLPNWYGVNCSKYCE-EKDDKFGPYRCDNSTGEKICLPNWY---GVNCSKYCKEKG 2063

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCE 1691
              S N  C+ +TG+  C P   G  C        + + N  C+
Sbjct: 2064 DNSGNYRCDNSTGEKICLPNWYGVNCSKYCKEKDDNSGNYRCD 2106



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 30/120 (25%), Positives = 44/120 (36%), Gaps = 8/120 (6%)

Query: 1528 CVTSWDSSTCT--CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSG 1585
            C+  W    CT  C++   G      C  G  G   C+ D    G +C      +  + G
Sbjct: 1540 CLDDWYGGNCTTYCKSSN-GSDGHYYCN-GTNGERICLDDDDWYGGNCTTYCKSSNGSDG 1597

Query: 1586 ---CI-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
               C   +G+  C   W+GG+    C        H  CN  NG+  C ++ Y    T  C
Sbjct: 1598 HYYCNGTNGERICLDDWYGGNCTTYCKSSNGSDGHYCCNGTNGERICLDDWYGGNCTTYC 1657



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 35/146 (23%), Positives = 49/146 (33%), Gaps = 11/146 (7%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +GK+ C   W+G +    C        +  C+   G+  C  N Y   G      C+   
Sbjct: 2177 TGKKICLPNWYGTNCIKYCKEKGDNSGNYRCDNSTGEKICLPNWY---GVNCSKYCKEKD 2233

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWP 1708
              S N  CE +TG+  C P   G  C        E   NSG    +  C  S    +  P
Sbjct: 2234 DNSGNYRCENSTGEKICLPNWYGVNCSKYCK---EKDDNSG----HYRCENSTGEKICLP 2286

Query: 1709 RTKFGVETITDCPPGSSGRATRTCDE 1734
               +GV     C           CD+
Sbjct: 2287 NW-YGVNCSQHCKKKDDNSGHYKCDD 2311



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 5/87 (5%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C      +
Sbjct: 1433 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYCKS----S 1488

Query: 1649 AGSE-NSSCEAATGQCHCRPGVIGRAC 1674
             GS+ +  C    G+  C     G  C
Sbjct: 1489 NGSDGHYYCNGTNGERICLDNWYGGNC 1515



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1501 NGERICLDNWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1553



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 26/116 (22%), Positives = 39/116 (33%), Gaps = 2/116 (1%)

Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGY-TLTTSGC 1586
            C+  W    CT             C  G  G   C+ D      +  C+    +     C
Sbjct: 1610 CLDDWYGGNCTTYCKSSNGSDGHYCCNGTNGERICLDDWYGGNCTTYCKSSNGSYGHYYC 1669

Query: 1587 I-ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
               +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1670 NGTNGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1725



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1229 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1281



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1263 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1315



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1297 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1349



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1331 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1383



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1365 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1417



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1399 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1451



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1707 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1759



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1741 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1793



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1775 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1827



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1809 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1861



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC 1641
            +G+  C   W+GG+    C        H +CN  NG+  C ++ Y    T  C
Sbjct: 1843 NGERICLDDWYGGNCTTYCKSSNGSDGHYYCNGTNGERICLDDWYGGNCTTYC 1895



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 5/86 (5%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            +G+  C   W+GG+      C  + G + +C  ++GK  C ++ +       C P     
Sbjct: 1877 NGERICLDDWYGGNCT--TYCKSSNGSYYYCKHDSGKRVCLDDWHGERCNVYCKPRN--- 1931

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRAC 1674
                +  C+  TG+  C     G+ C
Sbjct: 1932 NSEGHYICDIMTGEKVCHKNWYGKNC 1957



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 40/182 (21%), Positives = 61/182 (33%), Gaps = 25/182 (13%)

Query: 1521 ICPPYSKCVTSWDSST-CTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGY 1579
            +C  Y  C+ + DSS   +C A   G     A   G   +  C P     G+   C+P  
Sbjct: 889  LCDTY--CIPTNDSSGHYSCNAS-TGEMICHAHWYGESCSTNCSPQNNSLGHF-ECDP-- 942

Query: 1580 TLTTSGCIESGKEECPGGWWGGSACGPCA--------CD--VTRGYHPHCNKENGKCHCK 1629
                    +SG + C  GW+G      C         CD  + R Y           H  
Sbjct: 943  --------QSGIKICHSGWFGPICSVHCKETNEKQYKCDTGLERRYATSLGLGRIVRHFA 994

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689
                  +G    +  Q  ++  ++ +C+  TG   C P   G  C     A +    N  
Sbjct: 995  RQETTAQGITFVIKKQALSSDHQHYNCDNTTGSKLCHPDWFGENCTVHCKAQSSDNQNYS 1054

Query: 1690 CE 1691
            C+
Sbjct: 1055 CD 1056



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 46/207 (22%), Positives = 70/207 (33%), Gaps = 13/207 (6%)

Query: 1491 IGTAQSLLNRPTVRENVRDGCQS--RADCMLSICPPYSKCVTSWDSSTCT--CEAGRVGP 1546
            I T + + ++    +N R  CQ+  R +           C   W    C+  CE    G 
Sbjct: 1941 IMTGEKVCHKNWYGKNCRKHCQTSTRGNYRCDNVTGDKICTQKWYGENCSVFCEQN-AGS 1999

Query: 1547 QCVSACELGPCGAARCVPDQTPKGYSCACEP-GYTLTTSGCIES-GKEECPGGWWGGSAC 1604
                 C  G  G   C+P+      S  CE          C  S G++ C   W+G +  
Sbjct: 2000 HY--KCNNGS-GKKICLPNWYGVNCSKYCEEKDDKFGPYRCDNSTGEKICLPNWYGVNCS 2056

Query: 1605 GPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCH 1664
              C        +  C+   G+  C  N Y   G      C+     S N  C+ +TG+  
Sbjct: 2057 KYCKEKGDNSGNYRCDNSTGEKICLPNWY---GVNCSKYCKEKDDNSGNYRCDNSTGEKI 2113

Query: 1665 CRPGVIGRACDACANAYAEVTPNSGCE 1691
            C P   G  C        + + N  C+
Sbjct: 2114 CLPNWYGTNCIKYCKEKGDNSGNYRCD 2140


>SB_35429| Best HMM Match : Laminin_EGF (HMM E-Value=5.3e-17)
          Length = 218

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 9/109 (8%)

Query: 1625 KCHCKENHYKP-EGTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRACDACANA-Y 1681
            +C       KP  G ++C  C+C     E   C+  TG+C +C     G  C+ CA+  Y
Sbjct: 1    RCAPGYTRVKPGPGFSKCTRCKCNRHSLE---CDPETGKCINCDHNTAGDRCEKCASGFY 57

Query: 1682 AEVTPNSGCEVVYDGCPRSFAGGVWWPRTKF---GVETITDCPPGSSGR 1727
             + T  +  +     CP + A   + P  +    G  T T C PG +GR
Sbjct: 58   GDATQGTPVDCKPCSCPLTIASNQFSPTCRIDSDGAPTCTACRPGYTGR 106


>SB_1249| Best HMM Match : Cadherin (HMM E-Value=0.0083)
          Length = 106

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIR 228
           +++ I A D D G+N  + Y++ GG++  +F+++S +G + +    LD E   SY L+I 
Sbjct: 8   LLSSIAAVDPDAGSNGQLTYSMSGGDS--RFTLNSATGRLQISPAGLDRELKDSYDLIIN 65

Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
             D GSP  + + +   N  + N+N      +LF
Sbjct: 66  VTDNGSPPNTRSQRSNNNNNNNNNNNNNNNITLF 99



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 7/70 (10%)

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVT 337
           + A D D G N +LTY+M+  D         T++  +G +  S   LDRE +  Y L++ 
Sbjct: 12  IAAVDPDAGSNGQLTYSMSGGDSR------FTLNSATGRLQISPAGLDRELKDSYDLIIN 65

Query: 338 ATDGGDPPRS 347
            TD G PP +
Sbjct: 66  VTDNGSPPNT 75



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 12/78 (15%)

Query: 485 GTTVLV--VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDR 541
           G TVL+  ++A D D G N Q+TYS+S           D +F +N  TG +  +   LDR
Sbjct: 4   GGTVLLSSIAAVDPDAGSNGQLTYSMSG---------GDSRFTLNSATGRLQISPAGLDR 54

Query: 542 ETMSGYLLTVTARDGGVP 559
           E    Y L +   D G P
Sbjct: 55  ELKDSYDLIINVTDNGSP 72



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 4/70 (5%)

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAV 658
           +S + A D D G NG++ Y +   D     F ++ A+G ++ + A LDRE   ++DL   
Sbjct: 9   LSSIAAVDPDAGSNGQLTYSMSGGD---SRFTLNSATGRLQISPAGLDRELKDSYDLIIN 65

Query: 659 AIDGGTPPQS 668
             D G+PP +
Sbjct: 66  VTDNGSPPNT 75



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 9/71 (12%)

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
           +  I A DPD G N  + YS+ GGD  + F+L +  G  +   ++   LD E  +  Y+L
Sbjct: 9   LSSIAAVDPDAGSNGQLTYSMSGGD--SRFTLNSATGRLQ---ISPAGLDREL-KDSYDL 62

Query: 766 VIRA---ASPP 773
           +I      SPP
Sbjct: 63  IINVTDNGSPP 73


>SB_9975| Best HMM Match : 7tm_2 (HMM E-Value=1.9e-38)
          Length = 1101

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 14/121 (11%)

Query: 2204 WSTLRGSGEWSRVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVL--VDEVDVEFIPEP 2261
            WS  RG+  WS  GC    D D         L  C C+HL+ FA+L  V E  ++   E 
Sbjct: 433  WSLNRGN--WSSSGCKMTSDPD-------ERLAQCECDHLTNFAILMQVHEFKIDRAHEK 483

Query: 2262 SLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALK 2321
            +L   + +Y    ISL  L  + A    +    A+   SIHK+L+ ++ +A++++L  + 
Sbjct: 484  AL--QLITYVGCGISLFGLALTLATFLSLE-TLASERTSIHKNLVVAIGLAQIIFLAGID 540

Query: 2322 A 2322
            A
Sbjct: 541  A 541


>SB_46889| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 754

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 39/134 (29%), Positives = 50/134 (37%), Gaps = 13/134 (9%)

Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVP 1564
            D C++  D C  S C     CV   +  +CTC AG  G  C   +  C   PC       
Sbjct: 214  DKCENNDDECKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCKTDIDECAGNPCANGGTCK 273

Query: 1565 DQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC--NKE 1622
            D    G++C C  GY+ +T  C E   +EC G      A G    D   G+   C     
Sbjct: 274  DGI-NGFTCECPVGYSGST--C-EIDIDECAG---NPCANGGTCKDGINGFTCECPVGYS 326

Query: 1623 NGKCHCKENHYKPE 1636
               C      Y PE
Sbjct: 327  GSTCEIGVKCYNPE 340



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 7/64 (10%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362
            C      C S+PC NG  C D  + Y C C  G TGK+C     +  G P   GG   DG
Sbjct: 216  CENNDDECKSSPCKNGGTCVDGINRYSCTCVAGFTGKNCKTDIDECAGNPCANGGTCKDG 275

Query: 1363 MLSF 1366
            +  F
Sbjct: 276  INGF 279



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 7/64 (10%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DG 1362
            C      C+  PC NG  C D  + + C+C  G++G  C     +  G P   GG   DG
Sbjct: 254  CKTDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTCEIDIDECAGNPCANGGTCKDG 313

Query: 1363 MLSF 1366
            +  F
Sbjct: 314  INGF 317



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 10/72 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  FTC+CP G++G  CE  + + +      G+ C +G  C    + GI    C     Y
Sbjct: 276  INGFTCECPVGYSGSTCEIDIDECA------GNPCANGGTC----KDGINGFTCECPVGY 325

Query: 1099 TTAVCELRARSF 1110
            + + CE+  + +
Sbjct: 326  SGSTCEIGVKCY 337



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+  PC NG  C D  + + C+C  G++G  C
Sbjct: 292  CEIDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTC 330



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  ++C C  GFTG NC+T + + +      G+ C +G  C    + GI    C     Y
Sbjct: 238  INRYSCTCVAGFTGKNCKTDIDECA------GNPCANGGTC----KDGINGFTCECPVGY 287

Query: 1099 TTAVCEL 1105
            + + CE+
Sbjct: 288  SGSTCEI 294



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 10/61 (16%)

Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103
            C CP GF+G  CE       C+     S C++G  CV     GI    C+  A +T   C
Sbjct: 205  CHCPAGFSGDKCEN--NDDECK----SSPCKNGGTCV----DGINRYSCTCVAGFTGKNC 254

Query: 1104 E 1104
            +
Sbjct: 255  K 255


>SB_11569| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 488

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 5/63 (7%)

Query: 1281 FVGCISDFYIDHKFI---DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYIC 1337
            FVGC+++  ++   +    L+  VA  G + G     S+C   PC NG  C + WD+Y C
Sbjct: 249  FVGCMNNIKLNGALVRPRKLSKEVA--GAVIGRCSITSKCFPNPCQNGGACKESWDSYTC 306

Query: 1338 DCK 1340
            DC+
Sbjct: 307  DCQ 309



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/44 (31%), Positives = 25/44 (56%)

Query: 1181 GKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGA 1224
            GK  + V  N+ D  WHTV++    R++ + LD+ +   + AG+
Sbjct: 3    GKHHVIVGENLDDNKWHTVKVARNQRSLLLTLDNKETRTNTAGS 46



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 2/61 (3%)

Query: 1482 FEGCIQDVRIGTAQSLLNRPT--VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTC 1539
            F GC+ ++++  A     + +  V   V   C   + C  + C     C  SWDS TC C
Sbjct: 249  FVGCMNNIKLNGALVRPRKLSKEVAGAVIGRCSITSKCFPNPCQNGGACKESWDSYTCDC 308

Query: 1540 E 1540
            +
Sbjct: 309  Q 309


>SB_26778| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1050

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 39/153 (25%), Positives = 50/153 (32%), Gaps = 4/153 (2%)

Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCI 1587
            C   W    CT             C  G  GA  C P+      +  C+P    T     
Sbjct: 565  CHKDWYGDLCTTFCKNKDSSEHYTCN-GTTGARICFPNWYGVNCTRFCKPDNESTFFCDK 623

Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647
             +G   C  GW+G +    C        H  C K +G   C EN Y   G A    C+  
Sbjct: 624  STGTRVCNAGWYGINCTTQCVGRNDSFGHYTCQKISGAKICHENWY---GQACTTFCEAR 680

Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
               + + SC    GQ  C     G  CD   N+
Sbjct: 681  NDSTGHYSCNLTNGQKVCHRDWYGPFCDVNCNS 713



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 7/121 (5%)

Query: 1558 GAARCVPDQTPKGYSCACEPGYTLTTSG---CIESGKEECPGGWWGGSACGPCACDVTRG 1614
            G+  C PD      +  C P  + T++G   C+ +G + C  GW+G +    C       
Sbjct: 128  GSRLCHPDWYGSYCTIYCSPKNS-TSAGYYTCLSTGSKRCISGWYGQNCTTYCVPQNDEF 186

Query: 1615 YHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
             +  C+ E  K  C  + Y       C P +    G  +  C+  TGQ  C P      C
Sbjct: 187  ANYTCSDEGIKI-CANDWYNANCNVYCKPHRDDFIG--HFDCKNQTGQKVCMPNWYNDNC 243

Query: 1675 D 1675
            +
Sbjct: 244  N 244



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 24/92 (26%), Positives = 33/92 (35%), Gaps = 6/92 (6%)

Query: 1589 SGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            SG + C   W+G +    C        H  CN  NG+  C  + Y P     C       
Sbjct: 659  SGAKICHENWYGQACTTFCEARNDSTGHYSCNLTNGQKVCHRDWYGPFCDVNC------N 712

Query: 1649 AGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
            + S + +C   TG   C     G  CD   N+
Sbjct: 713  SNSSHFTCNKTTGARVCHSNWYGTYCDVYCNS 744



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 36/164 (21%), Positives = 56/164 (34%), Gaps = 13/164 (7%)

Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647
            ++G +EC   W+G      C        H  C+   G   C    Y P  T  C+P    
Sbjct: 323  KTGLKECFNHWYGPDCTTNCTPRNDSFGHYECDSSTGAVVCHSGWYGPTCTVNCIPRN-- 380

Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWW 1707
                 + +C    G   C     G  C+       ++  +SG    +  C R+ +G    
Sbjct: 381  -DSGGHYTCNETDGAKICDKHWYGTHCNVFCR---DMNDSSG----HYFCNRT-SGAKIC 431

Query: 1708 PRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMF--NCT 1749
                +GV     C P +  R   +CD        D + +  NCT
Sbjct: 432  RNDWYGVNCTEYCTPRNKVRGHYSCDMATGAKICDSNWYGLNCT 475



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 27/108 (25%), Positives = 42/108 (38%), Gaps = 6/108 (5%)

Query: 1570 GYSCACEPGYTLTTSG---CIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
            G +C     YT   +G   C+  G++ C   ++G      C        H  C+++ G  
Sbjct: 71   GRACDVYCSYTDDINGHYYCLNDGQQACLNDYYGTLCKTYCYPHNDSTGHYTCHQDTGSR 130

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
             C  + Y    T  C P    +AG    +C  +TG   C  G  G+ C
Sbjct: 131  LCHPDWYGSYCTIYCSPKNSTSAG--YYTC-LSTGSKRCISGWYGQNC 175



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 17/56 (30%), Positives = 23/56 (41%), Gaps = 3/56 (5%)

Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            CN + G   C  + Y P+ T  C P        E   C+++TG   C  G  G  C
Sbjct: 320  CNNKTGLKECFNHWYGPDCTTNCTPRNDSFGHYE---CDSSTGAVVCHSGWYGPTC 372


>SB_47530| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 939

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 20/47 (42%), Positives = 23/47 (48%)

Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            L GC      C S PC NG  C DL  +Y CDC +G  G +C    G
Sbjct: 177  LYGCVADGYECLSTPCLNGGTCVDLVASYRCDCIKGFNGTNCQYKLG 223


>SB_44915| Best HMM Match : VWA (HMM E-Value=0)
          Length = 541

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 17/39 (43%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      CSS+PC NGA C      Y C+C   H GK+C
Sbjct: 298  CTADVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 336



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/32 (50%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSS+PC NGA C      Y C+C   H GK+C
Sbjct: 44   CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 75



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%)

Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348
            L G   +   C S PC NG  CS +     Y C C  G+TGK+C
Sbjct: 255  LEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNC 298



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%)

Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093
            PI   + +TC C  G+TG NC   + + S       S C++G+ C+ ++ G   C+ CS
Sbjct: 278  PISSGSDYTCACAAGYTGKNCTADVDECS------SSPCQNGASCI-KKVGRYFCE-CS 328



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 10/86 (11%)

Query: 1501 PTVRENVRDGCQSRAD-CMLSICPPYSKC--VTSWDSSTCTCEAGRVGPQC---VSACEL 1554
            P++ E + +G  +  D C+   C     C  ++S    TC C AG  G  C   V  C  
Sbjct: 249  PSLPE-ILEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTADVDECSS 307

Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGY 1579
             PC   A C+  +    Y C C   +
Sbjct: 308  SPCQNGASCI--KKVGRYFCECSTAH 331


>SB_32721| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 637

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 52/183 (28%), Positives = 67/183 (36%), Gaps = 37/183 (20%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAAR-----CVPD 1565
            C++ A C  + C     C    D   CTC +G  G  C    E G   A +     C+PD
Sbjct: 432  CEAEAQCKHAPCHNGGTCTELHDGFQCTCSSGYRGNTCKGDAEYGIEAAQKRTSEVCLPD 491

Query: 1566 QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGS-------ACGPCACDVT-----R 1613
                G SC     Y +      +  K  CP G+ G S       A  PC  D T      
Sbjct: 492  PCHNGGSC-----YIVD-----DKFKCFCPPGFKGDSCERNDFCASDPCLNDGTCKETPA 541

Query: 1614 GYHPHCNKENGKCHCK-ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGR 1672
            GY   C  E    +C+ ENH KP       PC+      E         +CHC+ G  G 
Sbjct: 542  GYRCMCRPEFRGKNCETENHCKPVN-----PCENNGLCIETQD----NYRCHCKLGYKGF 592

Query: 1673 ACD 1675
             C+
Sbjct: 593  NCE 595



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/36 (44%), Positives = 22/36 (61%)

Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            K++RC   PC NG  C+D+ + Y C C  G+ G DC
Sbjct: 397  KKARCHPNPCQNGGSCTDVRNGYECTCLTGYKGHDC 432



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E  ++C  APC+NG  C++L D + C C  G+ G  C
Sbjct: 433  EAEAQCKHAPCHNGGTCTELHDGFQCTCSSGYRGNTC 469



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 41/167 (24%), Positives = 58/167 (34%), Gaps = 12/167 (7%)

Query: 1514 RADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKG 1570
            +A C  + C     C    +   CTC  G  G  C   + C+  PC     C   +   G
Sbjct: 398  KARCHPNPCQNGGSCTDVRNGYECTCLTGYKGHDCEAEAQCKHAPCHNGGTCT--ELHDG 455

Query: 1571 YSCACEPGYT-LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
            + C C  GY   T  G  E G E           C P  C    G   +   +  KC C 
Sbjct: 456  FQCTCSSGYRGNTCKGDAEYGIEAAQKR--TSEVCLPDPCH--NGGSCYIVDDKFKCFCP 511

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRACD 1675
               +K +       C      ++ +  E   G +C CRP   G+ C+
Sbjct: 512  PG-FKGDSCERNDFCASDPCLNDGTCKETPAGYRCMCRPEFRGKNCE 557



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 50/182 (27%), Positives = 58/182 (31%), Gaps = 25/182 (13%)

Query: 1549 VSACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIES-GKEEC-PGGWWGGSACG 1605
            V  CE  PC    +C          C C PGY  T   C  +  K  C P     G +C 
Sbjct: 356  VYGCEPNPCLHDGKCHRTHHRTRIRCVCMPGY--TGQRCQRALKKARCHPNPCQNGGSC- 412

Query: 1606 PCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCH 1664
                DV  GY   C      C      +  E  A+C    C+  G   +  E   G QC 
Sbjct: 413  ---TDVRNGY--ECT-----CLTGYKGHDCEAEAQCKHAPCHNGG---TCTELHDGFQCT 459

Query: 1665 CRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGS 1724
            C  G  G  C   A    E       EV     P    G  +    KF       CPPG 
Sbjct: 460  CSSGYRGNTCKGDAEYGIEAAQKRTSEVCLPD-PCHNGGSCYIVDDKFK----CFCPPGF 514

Query: 1725 SG 1726
             G
Sbjct: 515  KG 516



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 8/69 (11%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            T   C C  G+TG  C+  L KA C  +     C++G  C   R G      C+    Y 
Sbjct: 377  TRIRCVCMPGYTGQRCQRALKKARCHPNP----CQNGGSCTDVRNG----YECTCLTGYK 428

Query: 1100 TAVCELRAR 1108
               CE  A+
Sbjct: 429  GHDCEAEAQ 437



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 13/37 (35%), Positives = 18/37 (48%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E+   C+S PC N   C +    Y C C+    GK+C
Sbjct: 520  ERNDFCASDPCLNDGTCKETPAGYRCMCRPEFRGKNC 556



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 1/38 (2%)

Query: 1312 EKRSRCSSA-PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E  + C    PC N   C +  D Y C CK G+ G +C
Sbjct: 557  ETENHCKPVNPCENNGLCIETQDNYRCHCKLGYKGFNC 594



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 15/47 (31%), Positives = 19/47 (40%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A+ G  A        C   PC+NG  C  + D + C C  G  G  C
Sbjct: 473  AEYGIEAAQKRTSEVCLPDPCHNGGSCYIVDDKFKCFCPPGFKGDSC 519


>SB_29838| Best HMM Match : EGF (HMM E-Value=1.2e-15)
          Length = 373

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 18/37 (48%), Positives = 22/37 (59%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E    C+S PC NGA C+D  + Y C C  G TGK+C
Sbjct: 265  ENIDECASGPCQNGATCNDDVNKYTCSCIPGFTGKNC 301



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 3/46 (6%)

Query: 1537 CTCEAGRVGPQC--VSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580
            C C AG  G +C  +  C  GPC       D   K Y+C+C PG+T
Sbjct: 253  CHCLAGFSGDKCENIDECASGPCQNGATCNDDVNK-YTCSCIPGFT 297



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 13/20 (65%), Positives = 14/20 (70%)

Query: 1039 VTSFTCQCPEGFTGVNCETI 1058
            V  +TC C  GFTG NCETI
Sbjct: 285  VNKYTCSCIPGFTGKNCETI 304


>SB_13163| Best HMM Match : VWA (HMM E-Value=2.3e-32)
          Length = 318

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 17/39 (43%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      CSS+PC NGA C      Y C+C   H GK+C
Sbjct: 94   CTADVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 132



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%)

Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348
            L G   +   C S PC NG  CS +     Y C C  G+TGK+C
Sbjct: 51   LEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNC 94



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%)

Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093
            PI   + +TC C  G+TG NC   + + S       S C++G+ C+ ++ G   C+ CS
Sbjct: 74   PISSGSDYTCACAAGYTGKNCTADVDECS------SSPCQNGASCI-KKVGRYFCE-CS 124



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 10/86 (11%)

Query: 1501 PTVRENVRDGCQSRAD-CMLSICPPYSKC--VTSWDSSTCTCEAGRVGPQC---VSACEL 1554
            P++ E + +G  +  D C+   C     C  ++S    TC C AG  G  C   V  C  
Sbjct: 45   PSLPE-ILEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTADVDECSS 103

Query: 1555 GPC-GAARCVPDQTPKGYSCACEPGY 1579
             PC   A C+  +    Y C C   +
Sbjct: 104  SPCQNGASCI--KKVGRYFCECSTAH 127


>SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0)
          Length = 2411

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 1258 LTGPLQIGGLPNIPSSFQVK---NKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKR 1314
            L  PL +G +    ++ Q +   +  FVGCI DF ++    DL    A    L     +R
Sbjct: 2143 LDSPLYLG-VSQSEANLQTRVGVSTSFVGCIRDFRVEDP--DLRLRAASFDQLTVNQVRR 2199

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
              C    C NG  C+     Y C+C+ G TG  C
Sbjct: 2200 CGCRDGGCANGGVCTKRIKDYRCECRTGFTGSRC 2233


>SB_5993| Best HMM Match : EGF_2 (HMM E-Value=9e-14)
          Length = 360

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 38/136 (27%), Positives = 54/136 (39%), Gaps = 22/136 (16%)

Query: 1539 CEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGW 1598
            C  GR G  C   C    C         T K   C C  G+T     C     + C  G+
Sbjct: 104  CPTGRFGAGCTGVCT---CHRGSICDHVTGK---CHCGLGWTGVK--C----DQVCKEGY 151

Query: 1599 WGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ--CYAAGS----E 1652
            +G +    CAC +  G    C++ +G C C    Y  +    C P +   Y AG      
Sbjct: 152  YGVNCEHKCAC-LNGGT---CDRVSGCCECNSGWYGDKCQYRCPPGRFGLYCAGICKCVN 207

Query: 1653 NSSCEAATGQCHCRPG 1668
              SC+  +G+C+C+PG
Sbjct: 208  GESCDPVSGECYCKPG 223



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 10/88 (11%)

Query: 1593 ECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAEC------LPCQC 1646
            ECP G +G    G C C   RG    C+   GKCHC       +    C      + C+ 
Sbjct: 103  ECPTGRFGAGCTGVCTCH--RG--SICDHVTGKCHCGLGWTGVKCDQVCKEGYYGVNCEH 158

Query: 1647 YAAGSENSSCEAATGQCHCRPGVIGRAC 1674
              A     +C+  +G C C  G  G  C
Sbjct: 159  KCACLNGGTCDRVSGCCECNSGWYGDKC 186



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 5/84 (5%)

Query: 1644 CQCYAAGSENSSCEAATGQCHCRPGVIGRACD-ACANAYAEVTPNSGCEVVYDGCPRSFA 1702
            C C+      S C+  TG+CHC  G  G  CD  C   Y  V     C  +  G     +
Sbjct: 117  CTCH----RGSICDHVTGKCHCGLGWTGVKCDQVCKEGYYGVNCEHKCACLNGGTCDRVS 172

Query: 1703 GGVWWPRTKFGVETITDCPPGSSG 1726
            G        +G +    CPPG  G
Sbjct: 173  GCCECNSGWYGDKCQYRCPPGRFG 196



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 34/118 (28%), Positives = 47/118 (39%), Gaps = 21/118 (17%)

Query: 1521 ICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580
            +C  +   +    +  C C  G  G +C   C+ G  G   C        + CAC  G T
Sbjct: 116  VCTCHRGSICDHVTGKCHCGLGWTGVKCDQVCKEGYYG-VNC-------EHKCACLNGGT 167

Query: 1581 L-TTSGCIE--SG------KEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
                SGC E  SG      +  CP G +G    G C C    G    C+  +G+C+CK
Sbjct: 168  CDRVSGCCECNSGWYGDKCQYRCPPGRFGLYCAGICKC--VNG--ESCDPVSGECYCK 221


>SB_4760| Best HMM Match : EGF (HMM E-Value=8.29989e-42)
          Length = 240

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 32/126 (25%), Positives = 46/126 (36%), Gaps = 7/126 (5%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA---CELGPC-GAARCVPDQTPKGYS 1572
            C  + C    +C  +  +  C+C  G  G +C ++   C+  PC    +CV   +  GY 
Sbjct: 41   CAPNPCEHDGECSVAGKNYDCSCSLGWKGEKCEASQGKCQKNPCMNGGKCVETLSGTGYE 100

Query: 1573 CACEPGYTLTTSGCIESG-KEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKEN 1631
            C+C  GY       I++     C  G    S  G   C  T  Y    N    K H    
Sbjct: 101  CSCPSGYRGEVCDVIDNCLSNPCQNGATCNSVAGGFTCTCTPEYRG--NSVTRKRHVTLT 158

Query: 1632 HYKPEG 1637
            H    G
Sbjct: 159  HVTMAG 164



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 1540 EAGRVGPQCVSA-CELGPCGAARCVPDQTPKGYSCACEPGYT 1580
            + G    QCV   CE  PC   RC+ +     Y CAC+ GYT
Sbjct: 194  QEGTESYQCVKKMCEPNPCQHGRCI-EVNDDDYQCACDAGYT 234



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 2/41 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSD-LWDT-YICDCKEGHTGKDC 1348
            C   + +C   PC NG +C + L  T Y C C  G+ G+ C
Sbjct: 72   CEASQGKCQKNPCMNGGKCVETLSGTGYECSCPSGYRGEVC 112



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 14/37 (37%), Positives = 17/37 (45%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            C+  PC +  ECS     Y C C  G  G+ C  S G
Sbjct: 41   CAPNPCEHDGECSVAGKNYDCSCSLGWKGEKCEASQG 77



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 13/35 (37%), Positives = 17/35 (48%)

Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            +  C   PC +G       D Y C C  G+TGK+C
Sbjct: 204  KKMCEPNPCQHGRCIEVNDDDYQCACDAGYTGKNC 238


>SB_46360| Best HMM Match : EGF (HMM E-Value=0)
          Length = 352

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 46/168 (27%), Positives = 56/168 (33%), Gaps = 14/168 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  + C  Y  C       TC C  G  G  C   +  CE  PC   A C  D   KGY
Sbjct: 127  DCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL-KGY 185

Query: 1572 SCACEPGYTLTTSGCIESGKEEC--PGGWWGGSACGPCACDVTRGYHPHCNKENGKC--- 1626
            SC+C  G T           + C   G      +   C C  +    P C +    C   
Sbjct: 186  SCSCPTGVTGRHCDVSICDSKPCRNNGSCVLTQSGYQCLC-ASSFTSPQCQRSIDDCEHA 244

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            HC  N      +     C C   G     CE    +CH +P   G  C
Sbjct: 245  HCL-NGATCVDSDNAYKCSC-LEGYYGKHCE-LIDRCHSQPCQNGATC 289



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 4/55 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG 1360
            C      C+++PC N A C+DL + + C C  G+ G+ CA    D T  P + GG
Sbjct: 7    CEANIDDCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGG 61



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 48/189 (25%), Positives = 63/189 (33%), Gaps = 27/189 (14%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQT----PKGY 1571
            DC    C     CV +    TC C  G  G  C  + E+  CG+  C+ + T        
Sbjct: 51   DCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINC--SIEMDECGSYPCLNNGTCVDGRNRV 108

Query: 1572 SCACEPGYTLTTSGCIESGKEEC-PGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            +C C  G+   T    E   ++C P        C     D T   +P    E     C  
Sbjct: 109  TCTCAVGF---TGQFCEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGET----CA- 160

Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSC--EAATG-QCHCRPGVIGRACDACANAYAEVTPN 1687
                P    E  PCQ       N++C  +   G  C C  GV GR CD           N
Sbjct: 161  ---TPIDLCEAHPCQ------NNATCRMDPLKGYSCSCPTGVTGRHCDVSICDSKPCRNN 211

Query: 1688 SGCEVVYDG 1696
              C +   G
Sbjct: 212  GSCVLTQSG 220



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 46/162 (28%), Positives = 56/162 (34%), Gaps = 18/162 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            DC  S C   + C    +   C C AG  G  C   V  C   PC       D    GY+
Sbjct: 13   DCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGGTCVDAV-SGYT 71

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632
            C C PG+T   +  IE   +EC  G +     G C  D        C        C+ N 
Sbjct: 72   CLCMPGFT-GINCSIE--MDEC--GSYPCLNNGTCV-DGRNRVTCTCAVGFTGQFCEVN- 124

Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
                   +C P  C   G+       A   CHC PG  G  C
Sbjct: 125  -----IDDCDPAPCQNYGTCQDL--VADFTCHCYPGFTGETC 159



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/47 (40%), Positives = 22/47 (46%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A + T   C      C  A C NGA C D  + Y C C EG+ GK C
Sbjct: 226  ASSFTSPQCQRSIDDCEHAHCLNGATCVDSDNAYKCSCLEGYYGKHC 272



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 16/40 (40%), Positives = 18/40 (45%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C      C  APC N   C DL   + C C  G TG+ CA
Sbjct: 121  CEVNIDDCDPAPCQNYGTCQDLVADFTCHCYPGFTGETCA 160



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 16/33 (48%), Positives = 16/33 (48%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            RC S PC NGA C D      C C  G TG  C
Sbjct: 277  RCHSQPCQNGATCVDDDGVVFCKCAMGFTGTHC 309



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 999  DNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE-T 1057
            D  C   P    E C T +    A    N+ +    P+     ++C CP G TG +C+ +
Sbjct: 145  DFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPL---KGYSCSCPTGVTGRHCDVS 201

Query: 1058 ILTKASCEVDGDGSICRSGSQCV 1080
            I     C  +G   + +SG QC+
Sbjct: 202  ICDSKPCRNNGSCVLTQSGYQCL 224



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 12/68 (17%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI-CRSGSQCVARREGGILCQGCSIDAA 1097
            V+ +TC C  GFTG+NC       S E+D  GS  C +   CV  R   + C  C++   
Sbjct: 67   VSGYTCLCMPGFTGINC-------SIEMDECGSYPCLNNGTCVDGR-NRVTCT-CAV--G 115

Query: 1098 YTTAVCEL 1105
            +T   CE+
Sbjct: 116  FTGQFCEV 123



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 14/39 (35%), Positives = 17/39 (43%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C S PC N   C D  +   C C  G TG+ C
Sbjct: 83   CSIEMDECGSYPCLNNGTCVDGRNRVTCTCAVGFTGQFC 121



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 13/33 (39%), Positives = 16/33 (48%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            C+  PC  G  C D    Y C C  G TG +C+
Sbjct: 52   CTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCS 84



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 15/40 (37%), Positives = 17/40 (42%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDC 1348
            C      C + PC N A C  D    Y C C  G TG+ C
Sbjct: 159  CATPIDLCEAHPCQNNATCRMDPLKGYSCSCPTGVTGRHC 198


>SB_44887| Best HMM Match : EGF (HMM E-Value=4.1e-09)
          Length = 193

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 23/147 (15%)

Query: 1305 GTLAGCPEKR--SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDG 1362
            GTLA     R    C S PC +G  C+  ++ Y C C   +TG +C  +    +    + 
Sbjct: 41   GTLAKTARLRYVQECQSEPCQHGGTCTKRFNGYECSCAPTYTGANCEKALSSDYDLTINN 100

Query: 1363 MLSFNPLLRPI-QLPWLNALSIR--TRQRD-----AFVMSIQ----LKSGL-------LH 1403
              S NP    I ++P L A S+    R  D     A   S++    L+ GL       L+
Sbjct: 101  RAS-NPYAATIKKIPDLTAFSVSLWVRSDDEQPGTALSYSVENSGKLQDGLVLQDFGGLN 159

Query: 1404 YSYNGETMYLPMATLSDGAWHRIEIKW 1430
               N E  YL +  L DG WH + + W
Sbjct: 160  LFINDEATYLGVDVL-DGFWHHVAVTW 185


>SB_26480| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1772

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 39/140 (27%), Positives = 59/140 (42%), Gaps = 21/140 (15%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369
            C  +   C S PC +G  C+  ++ Y C C   +TG +C  +    +    +   S NP 
Sbjct: 1146 CETEVQECQSEPCQHGGTCTKRFNGYECSCAPTYTGANCEKALSSDYDLTINNRAS-NPY 1204

Query: 1370 LRPI-QLPWLNALSIR--TRQRD-----AFVMSIQ----LKSGL-------LHYSYNGET 1410
               I ++P L A S+    R  D     A   S++    L+ GL       L+   N E 
Sbjct: 1205 AATIKKIPDLTAFSVSLWVRSDDEQPGTALSYSVENSGKLQDGLVLQDFGGLNLFINDEA 1264

Query: 1411 MYLPMATLSDGAWHRIEIKW 1430
             YL +  L DG WH + + W
Sbjct: 1265 TYLGVDVL-DGFWHHVAVTW 1283



 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 6/68 (8%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC----ADSTGPPWRFG 1359
            +GTL  C      CS+ PC NG  C D    Y C C  G+TGK+C     +    P + G
Sbjct: 1104 SGTL--CQFNDDDCSAKPCRNGGSCIDNERFYTCACPAGYTGKNCETEVQECQSEPCQHG 1161

Query: 1360 GDGMLSFN 1367
            G     FN
Sbjct: 1162 GTCTKRFN 1169



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC CP G+TG NCET + +   E       C+ G  C  R  G      CS    YT A
Sbjct: 1133 YTCACPAGYTGKNCETEVQECQSEP------CQHGGTCTKRFNG----YECSCAPTYTGA 1182

Query: 1102 VCE 1104
             CE
Sbjct: 1183 NCE 1185



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC    C     C+ +    TC C AG  G  C   V  C+  PC     C   +   GY
Sbjct: 1114 DCSAKPCRNGGSCIDNERFYTCACPAGYTGKNCETEVQECQSEPCQHGGTCT--KRFNGY 1171

Query: 1572 SCACEPGYT 1580
             C+C P YT
Sbjct: 1172 ECSCAPTYT 1180



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 15/36 (41%), Positives = 23/36 (63%)

Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            K + C+S+PC N A+C D  ++Y C+C  G  G +C
Sbjct: 803  KVNDCASSPCNNNAKCIDTKESYRCECLPGFQGANC 838



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 4/66 (6%)

Query: 1502 TVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC- 1557
            + R    + C    DC  S C   +KC+ + +S  C C  G  G  C   V  C+  PC 
Sbjct: 792  SARSTRLEDCGKVNDCASSPCNNNAKCIDTKESYRCECLPGFQGANCDKEVDECDKQPCF 851

Query: 1558 GAARCV 1563
            GAA CV
Sbjct: 852  GAATCV 857



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 12/91 (13%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGA----ARCVPDQTPKGY 1571
            DC  + C    +CV      +C C  G  GPQC +     P  A    ++ V   T    
Sbjct: 1645 DCSSNPCRSRGQCVDRLKGYSCNCFPGYSGPQCSTVVPCSPLDAPVYGSKSVSGNT---V 1701

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGS 1602
            + +C+ GY +     + S    C  G W G+
Sbjct: 1702 NFSCQSGYQI-----VGSSSRSCTSGQWTGT 1727



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 7/48 (14%)

Query: 1309 GCPEK-------RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            GCP++        + CSS PC +  +C D    Y C+C  G++G  C+
Sbjct: 1631 GCPDRLVAPNVNSNDCSSNPCRSRGQCVDRLKGYSCNCFPGYSGPQCS 1678



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%)

Query: 1594 CPGGWW----GGSACGPCACDVTRGYHPH-CNKENGKCHCKENHYKPEGTAECLPCQC-- 1646
            CP G +    G   C  C  D T  +  H  N  N +  C   ++   G A C PC+   
Sbjct: 713  CPEGSYMNHEGALECKACP-DGTWTFGSHKANFTNCQAECGPGYFSATGIARCYPCKAGE 771

Query: 1647 YAAGSENSSCE 1657
            Y++G  N  CE
Sbjct: 772  YSSGERNKKCE 782



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 8/60 (13%)

Query: 1534 SSTCTCEAGR---VGPQCV--SACELGPCGAAR-CVPDQTPKGYSCACEPGYTLTTSGCI 1587
            SS+ +C +G+     P+C   + C +G    A+ C+   TP  Y+CAC  GY L  + CI
Sbjct: 1714 SSSRSCTSGQWTGTQPRCEDQNECSVGNHRCAQLCI--NTPGSYNCACAKGYRLDNNNCI 1771


>SB_33722| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 124

 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 37/114 (32%), Positives = 48/114 (42%), Gaps = 16/114 (14%)

Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELG--PCGA-ARCVPDQ 1566
            +C L +  CP  + C     S TC C+ G   V   C  +  C LG   C A A CV + 
Sbjct: 4    ECALGVANCPASADCFNYDGSYTCRCKRGYTLVNKTCTDIDECALGVATCPASADCVNND 63

Query: 1567 TPKGYSCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCACDVTRGY 1615
                Y+C C+PGYTL  + C +      G   CP      +  G   C   RGY
Sbjct: 64   G--SYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCFNYDGSYTCRCKRGY 115



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 7/87 (8%)

Query: 1507 VRDGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELGPCGAA 1560
            V   C    +C L +  CP  + CV +  S TC C+ G   V   C  +  C LG     
Sbjct: 36   VNKTCTDIDECALGVATCPASADCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCP 95

Query: 1561 RCVPDQTPKG-YSCACEPGYTLTTSGC 1586
                     G Y+C C+ GYTL    C
Sbjct: 96   ASADCFNYDGSYTCRCKRGYTLVNKTC 122


>SB_22957| Best HMM Match : EGF (HMM E-Value=7e-39)
          Length = 201

 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 43/173 (24%), Positives = 61/173 (35%), Gaps = 18/173 (10%)

Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVS----ACELGPC-GAARCVPDQTPKGYSCACEPGY 1579
            YS C+   ++ TC C     G  C +     C+  PC     C        Y+CAC  GY
Sbjct: 2    YSTCLDGVNNYTCLCGPRWTGRDCSTNLGNLCDPNPCQNGGVCKETFDRNNYTCACPQGY 61

Query: 1580 T-LTTSGCIESGKE-ECPGGWW---GGSACGPCACDVTRGYHP-HCNKENGKCH---CKE 1630
            T    +G +   +   C  G       +A     C    G++   C +    C    CK 
Sbjct: 62   TGWNCNGTLHPCETLNCNNGGTCQKQSNASDDYVCVCVTGFNGIRCEQNIDDCASLPCK- 120

Query: 1631 NHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPG--VIGRACDACANAY 1681
             H K         C C  +G E   C+    +C  +PG  + G  CD     Y
Sbjct: 121  -HGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNGGTCDNYLGTY 172



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 9/76 (11%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCE-AGRVGPQC---VSACEL--GPC-GAARCV 1563
            C+   D   S+   + KCV   ++ TC C  +G  GP+C   ++ C++  GPC     C 
Sbjct: 107  CEQNIDDCASLPCKHGKCVDGVNNHTCNCPGSGYEGPKCDVDINECKVQPGPCLNGGTC- 165

Query: 1564 PDQTPKGYSCACEPGY 1579
             D     Y C+C+ GY
Sbjct: 166  -DNYLGTYGCSCKAGY 180



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 14/31 (45%), Positives = 19/31 (61%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            PC NG  C +   TY C CK G+ GK+C ++
Sbjct: 158  PCLNGGTCDNYLGTYGCSCKAGYRGKNCQEN 188



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADSTGP 1354
            C   PC NG  C + +D   Y C C +G+TG +C  +  P
Sbjct: 33   CDPNPCQNGGVCKETFDRNNYTCACPQGYTGWNCNGTLHP 72



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 13/37 (35%), Positives = 19/37 (51%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS 1077
            ++TC CP+G+TG NC   L         +G  C+  S
Sbjct: 52   NYTCACPQGYTGWNCNGTLHPCETLNCNNGGTCQKQS 88


>SB_40913| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 656

 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C S PC NGA C+D  + Y C CK G+TG  C
Sbjct: 364  CQQDINECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVC 402



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C S PC NGA C+D  + Y C C  G+TG +C
Sbjct: 326  CETDINECQSNPCLNGATCTDHVNGYTCSCALGYTGIEC 364



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TC+C  G  G +C   ++ C+  PC       D    GY+
Sbjct: 332  ECQSNPCLNGATCTDHVNGYTCSCALGYTGIECQQDINECQSNPCLNGATCTDHV-NGYT 390

Query: 1573 CACEPGYT 1580
            C+C+ GYT
Sbjct: 391  CSCKLGYT 398



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 1315 SRCSSAPCYNGAECSDLW--DTYICDCKEGHTGKDC 1348
            S C S PC +G+ C   +  DTY C C +G+TG+ C
Sbjct: 291  SPCQSDPCLHGSRCLAAYTDDTYTCACLQGYTGRHC 326



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 8/93 (8%)

Query: 1037 YPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICR---SGSQC-VARREGGILCQ-- 1090
            Y   ++TC C +G+TG +CET + +       +G+ C    +G  C  A    GI CQ  
Sbjct: 308  YTDDTYTCACLQGYTGRHCETDINECQSNPCLNGATCTDHVNGYTCSCALGYTGIECQQD 367

Query: 1091 --GCSIDAAYTTAVCELRARSFPVSSFLTFPGL 1121
               C  +     A C      +  S  L + G+
Sbjct: 368  INECQSNPCLNGATCTDHVNGYTCSCKLGYTGI 400



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 19/132 (14%)

Query: 1550 SACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG-WWGGSACGPC 1607
            S C+  PC   +RC+   T   Y+CAC  GY  T   C E+   EC       G+ C   
Sbjct: 291  SPCQSDPCLHGSRCLAAYTDDTYTCACLQGY--TGRHC-ETDINECQSNPCLNGATC--- 344

Query: 1608 ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRP 1667
              D   GY   C        C+++        EC    C    +        T  C C+ 
Sbjct: 345  -TDHVNGYTCSCALGYTGIECQQD------INECQSNPCLNGATCTDHVNGYT--CSCKL 395

Query: 1668 GVIGRAC--DAC 1677
            G  G  C  D+C
Sbjct: 396  GYTGIVCQKDSC 407


>SB_48384| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1678

 Score = 46.0 bits (104), Expect = 4e-04
 Identities = 42/173 (24%), Positives = 64/173 (36%), Gaps = 20/173 (11%)

Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELGP--CGAARC 1562
            C    +C L +  CP  + CV +  S TC C+ G   V   C  V+ C   P  C     
Sbjct: 930  CDDIDECGLGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCTDVNECTETPYVCSGENS 989

Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKE 1622
            + + T   + C+C+ GYT   S  +     + P               + R    +C   
Sbjct: 990  ICENTDGSFKCSCKSGYTPKFSEAV----GDAPANLTSCDGKTAVHSKLVRNVIRYCVNN 1045

Query: 1623 NGK--CHCKENHYKPEGTAECLPCQC---YAAGSENSSCEAATGQ--CHCRPG 1668
            +G   C CK  +     T E +  +C    A    ++ C    G   C C+PG
Sbjct: 1046 DGSYTCKCKPGYTLVNNTCEDID-ECALGVATCPASADCVNNDGSYTCRCKPG 1097



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 40/163 (24%), Positives = 58/163 (35%), Gaps = 16/163 (9%)

Query: 1549 VSACELGP--CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606
            V+ C   P  C     + + T   + C+C+ GYT   S  +     + P           
Sbjct: 880  VNECTETPYVCSGNNSICENTDGSFKCSCKSGYTPKFSEAV----GDAPANLTSCDDIDE 935

Query: 1607 CACDV-TRGYHPHCNKENGK--CHCKENHYKPEGTA----ECLPCQCYAAGSENSSCEAA 1659
            C   V T      C   +G   C CK  +     T     EC     Y    ENS CE  
Sbjct: 936  CGLGVATCPASADCVNNDGSYTCRCKRGYTLVNKTCTDVNECTETP-YVCSGENSICENT 994

Query: 1660 TG--QCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRS 1700
             G  +C C+ G   +  +A  +A A +T   G   V+    R+
Sbjct: 995  DGSFKCSCKSGYTPKFSEAVGDAPANLTSCDGKTAVHSKLVRN 1037



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 12/73 (16%)

Query: 1571 YSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKE 1630
            Y+C C+PGYTL  + C +   +EC     G + C P + D         N  +  C CK 
Sbjct: 1049 YTCKCKPGYTLVNNTCEDI--DECA---LGVATC-PASADCVN------NDGSYTCRCKP 1096

Query: 1631 NHYKPEGTAECLP 1643
             +       E +P
Sbjct: 1097 GYELNNNECEAVP 1109


>SB_36058| Best HMM Match : VWA (HMM E-Value=7.4e-23)
          Length = 187

 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/32 (50%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSS+PC NGA C      Y C+C   H GK+C
Sbjct: 5    CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 36


>SB_28093| Best HMM Match : VWA (HMM E-Value=4.4e-33)
          Length = 222

 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/32 (50%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSS+PC NGA C      Y C+C   H GK+C
Sbjct: 5    CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 36


>SB_54456| Best HMM Match : EGF (HMM E-Value=2.3e-31)
          Length = 491

 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/37 (43%), Positives = 23/37 (62%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            ++ S+C   PC NGA C++  + YIC C  G  GK+C
Sbjct: 422  DEESKCEPNPCRNGAVCTETREKYICSCTYGFMGKNC 458



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPD 1565
            D C  ++ C  + C  ++ C    +   CTC  G  G  C   S CE  PC   A C   
Sbjct: 382  DRCDIQSKCFPNPCKNFATCTEHPNDYECTCHPGFHGKNCDEESKCEPNPCRNGAVCT-- 439

Query: 1566 QTPKGYSCACEPGY 1579
            +T + Y C+C  G+
Sbjct: 440  ETREKYICSCTYGF 453



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 14/39 (35%), Positives = 22/39 (56%)

Query: 1314 RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            +S+C   PC N A C++  + Y C C  G  GK+C + +
Sbjct: 387  QSKCFPNPCKNFATCTEHPNDYECTCHPGFHGKNCDEES 425



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            S C  +PC NG  CS + + Y C C  G+ G  C
Sbjct: 351  SPCEVSPCRNGGTCSAVGNEYRCVCALGYKGDRC 384


>SB_39378| Best HMM Match : VWA (HMM E-Value=0)
          Length = 2865

 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 16/32 (50%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSS+PC NGA C      Y C+C   H GK+C
Sbjct: 195  CSSSPCQNGASCIKKVGRYFCECSTAHVGKNC 226



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 17/33 (51%), Positives = 18/33 (54%), Gaps = 1/33 (3%)

Query: 1317 CSSAPCYNGAEC-SDLWDTYICDCKEGHTGKDC 1348
            C   PC NG  C S L  TY C C+EG  GK C
Sbjct: 2123 CYDMPCQNGGTCTSTLSRTYTCSCREGFAGKHC 2155



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 15/30 (50%), Positives = 17/30 (56%)

Query: 1319 SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            S PCYNG  C +    Y C C +G TGK C
Sbjct: 1451 SNPCYNGGTCVNEEGAYSCQCSDGFTGKHC 1480



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%)

Query: 1307 LAGCPEKRSRCSSAPCYNGAECSDL--WDTYICDCKEGHTGKDC 1348
            L G   +   C S PC NG  CS +     Y C C  G+TGK+C
Sbjct: 406  LEGVIAEPDPCLSKPCANGGTCSPISSGSDYTCACAAGYTGKNC 449



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 1489 VRIGTAQSLLNR-PTVRENVRDGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGP 1546
            ++  + + L+N  PT++E+V     S AD C+LS+C   SKC  S     C C +G  G 
Sbjct: 2332 IQADSMEELINFIPTIKESVL----SIADPCLLSLCKNGSKCTLSGSGFRCECASGYNGL 2387

Query: 1547 QCVSAC 1552
             C + C
Sbjct: 2388 LCQNVC 2393



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 16/37 (43%), Positives = 19/37 (51%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            S C S+PC NG  CS+    + C C  G  GK C  S
Sbjct: 1896 STCDSSPCLNGGFCSNTEIGFSCVCPVGFAGKTCEKS 1932



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 22/69 (31%), Positives = 24/69 (34%), Gaps = 6/69 (8%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV--SACELGPCGAARC----VPDQTPKG 1570
            C LS C     C       TCTC  G  G  C     C L       C    V   TP  
Sbjct: 2618 CALSPCKNGGSCSGDLSGYTCTCAFGWTGVNCEIRDFCALASVNGPACFNGGVCTNTPTS 2677

Query: 1571 YSCACEPGY 1579
            Y+C C  G+
Sbjct: 2678 YTCTCARGF 2686



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 14/32 (43%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+ +PC NG  CS     Y C C  G TG +C
Sbjct: 2618 CALSPCKNGGSCSGDLSGYTCTCAFGWTGVNC 2649



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 23/70 (32%), Positives = 26/70 (37%), Gaps = 5/70 (7%)

Query: 1291 DHKFIDLNSYVADNGTLAGC-----PEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTG 1345
            D KF+ L     D+G  A        E  + C   PC NG  CS      IC CK   TG
Sbjct: 1017 DDKFVFLLRNYNDSGVAANAFQDSVIEALNSCYINPCKNGGTCSTSASKLICACKPTFTG 1076

Query: 1346 KDCADSTGPP 1355
              C      P
Sbjct: 1077 SLCETECNIP 1086



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 1516 DCMLS-ICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELG 1555
            +C+ S IC     CV ++ S  C C   + GP C+  C+ G
Sbjct: 455  ECLDSRICAVERMCVNTYGSYQCVCTMDKYGPSCIYDCKSG 495



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 8/61 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDG----DGSICR---SGSQCV-ARREGGILCQ 1090
            ++ +TC C  G+TGVNCE     A   V+G    +G +C    +   C  AR   G+ C+
Sbjct: 2633 LSGYTCTCAFGWTGVNCEIRDFCALASVNGPACFNGGVCTNTPTSYTCTCARGFHGLRCE 2692

Query: 1091 G 1091
            G
Sbjct: 2693 G 2693


>SB_5376| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 1705

 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 38/127 (29%), Positives = 50/127 (39%), Gaps = 12/127 (9%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGP--CGA-ARCVPDQTPKGYSCACEPG 1578
            C   + C  +  S TCTC A   G   ++ CE+G   C A A C+   T   ++CAC  G
Sbjct: 16   CHRNATCANTHGSFTCTCIAVYTGDD-INECEVGSHNCHADATCI--NTDGSFTCACNVG 72

Query: 1579 YTLTTSGCIESGKEECPG---GWWGGSACGPCACDVTRGYH--PHCNKENGKCHCK-ENH 1632
            Y    + C E    E P          A  P         H   HC    G  +C  +N 
Sbjct: 73   YAGNGAFCQEGFDRENPTLDINECQRDALAPIHNHYAHNCHVDAHCTNTKGSFYCTCKNG 132

Query: 1633 YKPEGTA 1639
            Y  +GTA
Sbjct: 133  YSGDGTA 139



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTL 1581
            C P+++C  +  S  CTCE G  G   V+  ++  C +     D     ++C  +   T 
Sbjct: 884  CHPHAQCTNTKGSFYCTCEKGYSG-DGVNCTDIDECNSETLSGDHKHLAHNCHSDANCTN 942

Query: 1582 T 1582
            T
Sbjct: 943  T 943


>SB_30234| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 5222

 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 64/256 (25%), Positives = 89/256 (34%), Gaps = 29/256 (11%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570
            C    +  LS C P S        +   C  G + P   +  ++ PC A    PD TPK 
Sbjct: 2527 CPKGTNAPLS-CEPGSYQPNRGQGNCTKCGPGSMCPY-QNMTKVEPCKAGYYCPDGTPK- 2583

Query: 1571 YSCACEPGYTLTTSGCIESGK-EECPGGWWGGSAC-----GPCA----CD--VTRGYHPH 1618
                C  G     +G   S +  +CP G +   A      GPCA    C+          
Sbjct: 2584 ---PCGLGTYGNRTGLSSSDQCTDCPAGQFCSEAGLTMPKGPCAAGHFCEGGADSATPSP 2640

Query: 1619 CNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQC-HCRPGVIGRACDAC 1677
             +K      C   HY  EGT    P QC      N++  AA   C +C PG     C+  
Sbjct: 2641 SSKYPRNGLCPVGHYCVEGTQT--PEQCQPGTFRNTTGAAAFDHCLNCTPGWY---CEGF 2695

Query: 1678 ANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKD 1737
             N+     P   C   Y  CP +    V  P+ +F    ++            TCD    
Sbjct: 2696 GNS----KPTDKCAPGYY-CPENSQASVSEPKKQFANYKLSHSGYNQKREGQPTCDPCPA 2750

Query: 1738 VPWQDPDMFNCTTATF 1753
              + DPD   C +  +
Sbjct: 2751 GYYCDPDAKKCPSHNY 2766


>SB_15312| Best HMM Match : EGF (HMM E-Value=7.1e-21)
          Length = 77

 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 6/68 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            DC  S C   + CV   +  TCTC  G  G  C   ++ C   PC   A C  +     +
Sbjct: 4    DCAGSPCQNGATCVDGINKYTCTCAGGYTGTHCETDINECASSPCLNGATC--NDGVNLF 61

Query: 1572 SCACEPGY 1579
            SC+C PGY
Sbjct: 62   SCSCVPGY 69



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 15/32 (46%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+ +PC NGA C D  + Y C C  G+TG  C
Sbjct: 5    CAGSPCQNGATCVDGINKYTCTCAGGYTGTHC 36



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C+S+PC NGA C+D  + + C C  G+ G  C
Sbjct: 36   CETDINECASSPCLNGATCNDGVNLFSCSCVPGYIGVRC 74



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 12/38 (31%), Positives = 21/38 (55%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            +  +TC C  G+TG +CET + + +     +G+ C  G
Sbjct: 20   INKYTCTCAGGYTGTHCETDINECASSPCLNGATCNDG 57


>SB_53619| Best HMM Match : GPS (HMM E-Value=2.4e-15)
          Length = 457

 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 15/143 (10%)

Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEIDYDWSPYSEEPLL 2235
            L KPI + +    N+ +  S   P+CV W T R    WS  GCH               +
Sbjct: 196  LTKPIVITV--RNNKTSNNSEMVPKCVFWDTKRRG--WSSSGCHLSFS--------NATI 243

Query: 2236 INCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSIS-LPLLLTSWAALCLIRGGA 2294
              C C+H++ +AVL+   D+    + +   S+ +Y   ++S L + LT    + L     
Sbjct: 244  TECKCDHMTNYAVLMSIGDMPIPAKHTRALSIVTYIGCTLSILGVFLTVVTLISL--PVL 301

Query: 2295 ATVSNSIHKHLIFSVFMAELLYL 2317
             +    IH +L  +V ++++L+L
Sbjct: 302  RSERTRIHCNLCIAVGVSQILFL 324


>SB_40564| Best HMM Match : Laminin_EGF (HMM E-Value=3.5e-12)
          Length = 186

 Score = 45.2 bits (102), Expect = 8e-04
 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 8/108 (7%)

Query: 1569 KGYSC-ACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627
            +G  C  C+PG+   T    E G +EC     GG+A     C  T+  HP  +K      
Sbjct: 85   QGRQCDTCKPGFYRLTRDNPE-GCQEC-ACHHGGTANASNVCVTTQHEHPEQSKTVDPLS 142

Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
             +   + P    EC     Y AG+    C  ATGQC CR  V G+ C+
Sbjct: 143  DRWILFLPSA-CECDSGGTYPAGT----CNKATGQCQCRAHVTGKRCN 185


>SB_52271| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 89

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 16/32 (50%), Positives = 21/32 (65%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S+PC NGA C+D  + Y C C  G TG +C
Sbjct: 55   CASSPCQNGATCNDSVNKYTCSCIPGFTGTNC 86



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 8/54 (14%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLL 1370
            C+  PC NG  C+D  + + C C  G+TG  C          G DGML+ N +L
Sbjct: 5    CAGDPCANGGTCTDGINGFTCTCPAGYTGNTCGT--------GFDGMLTINFVL 50



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 24/82 (29%), Positives = 29/82 (35%), Gaps = 16/82 (19%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---------------VSACELGPCGAA 1560
            DC    C     C    +  TCTC AG  G  C               +  C   PC   
Sbjct: 4    DCAGDPCANGGTCTDGINGFTCTCPAGYTGNTCGTGFDGMLTINFVLDIDECASSPCQNG 63

Query: 1561 RCVPDQTPKGYSCACEPGYTLT 1582
                D   K Y+C+C PG+T T
Sbjct: 64   ATCNDSVNK-YTCSCIPGFTGT 84



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 10/73 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCET----ILT-KASCEVDG-DGSICRSGSQCVARREGGILCQGC 1092
            +  FTC CP G+TG  C T    +LT     ++D    S C++G+ C       +    C
Sbjct: 20   INGFTCTCPAGYTGNTCGTGFDGMLTINFVLDIDECASSPCQNGATC----NDSVNKYTC 75

Query: 1093 SIDAAYTTAVCEL 1105
            S    +T   CE+
Sbjct: 76   SCIPGFTGTNCEM 88


>SB_16119| Best HMM Match : EGF (HMM E-Value=2e-20)
          Length = 76

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C     C    +S  CTC AG  G +C   +  C  GPC       D   K Y+
Sbjct: 3    ECAGNPCANGGICKDGINSFKCTCPAGYTGSKCETDIDDCASGPCQNGATCNDGVNK-YT 61

Query: 1573 CACEPGYTLT 1582
            C+C PG+T T
Sbjct: 62   CSCIPGFTGT 71



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S PC NGA C+D  + Y C C  G TG +C
Sbjct: 35   CETDIDDCASGPCQNGATCNDGVNKYTCSCIPGFTGTNC 73



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+  PC NG  C D  +++ C C  G+TG  C
Sbjct: 4    CAGNPCANGGICKDGINSFKCTCPAGYTGSKC 35



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 14/38 (36%), Positives = 20/38 (52%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            + SF C CP G+TG  CET +   +     +G+ C  G
Sbjct: 19   INSFKCTCPAGYTGSKCETDIDDCASGPCQNGATCNDG 56



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 1039 VTSFTCQCPEGFTGVNCET 1057
            V  +TC C  GFTG NCET
Sbjct: 57   VNKYTCSCIPGFTGTNCET 75


>SB_52861| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1487

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 14/106 (13%)

Query: 1557 CGAARCVPDQTPKGYSCACEPGYTLTTSG-CIESGKEECPGGWWGGSACGPCACDVTRGY 1615
            C A +   D TP+ + C C+PGY    SG C+      C  G   G    P  C  + G+
Sbjct: 203  CSALQNCVD-TPEFFRCVCKPGYEQALSGQCV----PVCTQGCVNGKCTSPDVCTCSFGW 257

Query: 1616 -HPHCNKE---NGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCE 1657
              P+C+ E   NG  HC  N  K +    C  C+ +  GS    CE
Sbjct: 258  TGPNCSVECLCNGHGHC-ANATKRD---VCTDCRNHTTGSSCQYCE 299


>SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 933

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 60/215 (27%), Positives = 75/215 (34%), Gaps = 20/215 (9%)

Query: 1488 DVRIGTAQSLLNRPTVRENVR---DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEA--- 1541
            DVR+G  Q     PT  + VR    G   R  C   I   +             CE    
Sbjct: 383  DVRVGIHQDQSLNPTCNDRVRTVGQGQALRVQCNPPIPGRHIAIQMIGKGILTLCEVSVY 442

Query: 1542 GRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSG--CIESGKEECPGGWW 1599
             R  P     C+L   G  +   +       C C PG+ +   G  CI+   +EC     
Sbjct: 443  SRTAP-LADLCQLDNGGCEQVCYNLCNLKVKCGCYPGFKMAYDGRTCIDI--DECQVN-N 498

Query: 1600 GGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAA 1659
            GG       C  T G H HC   NG    + + Y  E   E   C    AG E+  CE  
Sbjct: 499  GGCDIFHGQCINTPGSH-HCACRNGYQLKENSKYVCEDLNE---CNVANAGCEH-ICENT 553

Query: 1660 TG--QCHCRPGVIGRACD-ACANAYAEVTPNSGCE 1691
             G   C CR G   +A    C N    +  N GCE
Sbjct: 554  HGSFNCDCRQGYKLKAGGYGCENINECLVKNGGCE 588



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 7/85 (8%)

Query: 1503 VRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTC------EAGRVGPQCVSACELGP 1556
            ++EN +  C+   +C ++       C  +  S  C C      +AG  G + ++ C +  
Sbjct: 525  LKENSKYVCEDLNECNVANAGCEHICENTHGSFNCDCRQGYKLKAGGYGCENINECLVKN 584

Query: 1557 CGAARCVPDQTPKGYSCACEPGYTL 1581
             G      D    GY C C PGY L
Sbjct: 585  GGCEHTCKDYEG-GYYCTCNPGYRL 608


>SB_26578| Best HMM Match : EGF (HMM E-Value=2.2e-35)
          Length = 136

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C ++ C     C       +C C+AG  G  C   V+ C + PC       ++   GYS
Sbjct: 63   ECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNE-HGGYS 121

Query: 1573 CACEPGYT 1580
            CAC+ G+T
Sbjct: 122  CACKAGFT 129



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 19   CEQDVNECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNC 57



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 57   CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 95



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/39 (43%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS  PC NG  C +    Y C CK G TGK+C
Sbjct: 95   CEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNC 133



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 26/147 (17%)

Query: 1536 TCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592
            +CTC++G  G  C   V+ C   PC       ++   GYSCAC+ G+  T   C E    
Sbjct: 7    SCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHG-GYSCACKVGF--TGKNC-EQDVN 62

Query: 1593 ECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCKENHYKPEGTAECLPCQCYAAG 1650
            EC        +  PC      G    C  E+G   C CK          +   C      
Sbjct: 63   EC--------SVNPCK---NGGV---CKNEHGGYSCACKAGFTGKNCEQDVNECSVNPC- 107

Query: 1651 SENSSCEAATG--QCHCRPGVIGRACD 1675
                 C+   G   C C+ G  G+ C+
Sbjct: 108  KNGGVCKNEHGGYSCACKAGFTGKNCE 134



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 8/72 (11%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS--GSQCVARREG--GILCQ----GC 1092
            +++C C  GFTG NCE  + + S     +G +C++  G    A + G  G  C+     C
Sbjct: 5    AYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNEC 64

Query: 1093 SIDAAYTTAVCE 1104
            S++      VC+
Sbjct: 65   SVNPCKNGGVCK 76



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 8/71 (11%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS--GSQCVARREG--GILCQ----GCS 1093
            ++C C  GFTG NCE  + + S     +G +C++  G    A + G  G  C+     CS
Sbjct: 44   YSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECS 103

Query: 1094 IDAAYTTAVCE 1104
            ++      VC+
Sbjct: 104  VNPCKNGGVCK 114



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 10/63 (15%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C  GFTG NCE  + +  C V+     C++G  C     GG     C+  A +T  
Sbjct: 82   YSCACKAGFTGKNCEQDVNE--CSVNP----CKNGGVC-KNEHGG---YSCACKAGFTGK 131

Query: 1102 VCE 1104
             CE
Sbjct: 132  NCE 134



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 29/110 (26%), Positives = 37/110 (33%), Gaps = 8/110 (7%)

Query: 1571 YSCACEPGYT--LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHC 1628
            YSC C+ G+T         E  K  C  G    +  G  +C    G+    N E     C
Sbjct: 6    YSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKVGFTGK-NCEQDVNEC 64

Query: 1629 KENHYKPEGTAE----CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
              N  K  G  +       C C  AG    +CE    +C   P   G  C
Sbjct: 65   SVNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDVNECSVNPCKNGGVC 113


>SB_26267| Best HMM Match : TSP_C (HMM E-Value=0)
          Length = 2996

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAP 473
            T     G +T+   LD++    Y++ +  TD+G G S    ++I + D N+  P+     
Sbjct: 1247 TMATSHGKLTLKAELDYEATTEYLIVMRITDTGRGTSGEIAIKIFVLDYNDNCPILPKVS 1306

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
            YT                 ATD D G+N  +T ++ S+
Sbjct: 1307 YTLKPIPPLQ-PQPFFTARATDKDSGLNGHVTPTIVSK 1343



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 15/149 (10%)

Query: 97   GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
            G L  +A LD E    Y ++++ TD     S  ++    I + ++D NDN P   + +YT
Sbjct: 1253 GKLTLKAELDYEATTEYLIVMRITDTGRGTSGEIA----IKIFVLDYNDNCPILPKVSYT 1308

Query: 157  VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216
            +   + I           +ATD D G N  +   I+      ++ +++ +  V    T  
Sbjct: 1309 L---KPIPPLQPQPFFTARATDKDSGLNGHVTPTIV----SKKYYMNNYTEIVWSNTTTQ 1361

Query: 217  YEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +EQ       I A DGG+P R +   L I
Sbjct: 1362 WEQT----YYIFAIDGGTPRRGDKIPLTI 1386



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 11/141 (7%)

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G +T    LD E  + YL+ +   D G    S    ++I V+D NDN P+  +  YT   
Sbjct: 1253 GKLTLKAELDYEATTEYLIVMRITDTG-RGTSGEIAIKIFVLDYNDNCPILPKVSYTLKP 1311

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
            +   L         ATD D GLNG +   +  K      + ++  + ++ +N     E  
Sbjct: 1312 I-PPLQPQPFFTARATDKDSGLNGHVTPTIVSK-----KYYMNNYTEIVWSNTTTQWEQ- 1364

Query: 651  ATHDLKAVAIDGGTPPQSSTV 671
             T+ +   AIDGGTP +   +
Sbjct: 1365 -TYYI--FAIDGGTPRRGDKI 1382



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 16/141 (11%)

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQES 265
            G ++L   LDYE    Y +V+R  D G  + S    + I + D NDN P     S   + 
Sbjct: 1253 GKLTLKAELDYEATTEYLIVMRITDTGRGT-SGEIAIKIFVLDYNDNCPILPKVSYTLKP 1311

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
            +    P  +   R  A D D G+N  +T T+  K Y  N    I       W  T+    
Sbjct: 1312 IPPLQPQPFFTAR--ATDKDSGLNGHVTPTIVSKKYYMNNYTEIV------WSNTT---- 1359

Query: 326  RETQAKYQLLVTATDGGDPPR 346
              TQ +    + A DGG P R
Sbjct: 1360 --TQWEQTYYIFAIDGGTPRR 1378



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 9/82 (10%)

Query: 747  ELVTMVDLDYESPRKKYELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNY 804
            +L    +LDYE+  + Y +V+R          ++ ++I V D NDN P++          
Sbjct: 1254 KLTLKAELDYEATTE-YLIVMRITDTGRGTSGEIAIKIFVLDYNDNCPILPKVSYTLK-- 1310

Query: 805  KDCFPVGPFGRVPAYDADVTDK 826
                P+ P    P + A  TDK
Sbjct: 1311 ----PIPPLQPQPFFTARATDK 1328


>SB_26085| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 484

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 21/140 (15%)

Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAG-------RVGPQCVSACEL---GPCG 1558
            D C+ R +C    C   + C+ +  S  C CE G        +   CV   E    G C 
Sbjct: 236  DKCRDRNECAYKNCGVGATCLNALGSYACQCEPGFRLDRTLGLSGVCVDMDECLVPGSC- 294

Query: 1559 AARCVPDQTPKGYSCACEPGYTL--TTSGCIESGK----EECPGGWWGGSACGPCACDVT 1612
                V     KG++C CE GY +    + CI+  +      CP G    +  G   CD  
Sbjct: 295  PEHSVCTNHVKGFTCECESGYLMDDLKAHCIDVDECALGATCPSGTNCVNTQGSFYCDCG 354

Query: 1613 RGYHPHCNKENGKCHCKENH 1632
             GYH      NG C    +H
Sbjct: 355  HGYH----AVNGTCQGMFDH 370



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 35/186 (18%)

Query: 1521 ICPPYSKCVTSWDSSTCTC---EAGRVGPQC--VSACELGPCG-AARCVPDQTPKGYSCA 1574
            ICP  + CV +  S  CTC    +   G +C   + C    CG  A C+       Y+C 
Sbjct: 208  ICPENTNCVNTHGSYECTCLGPFSPWFGDKCRDRNECAYKNCGVGATCL--NALGSYACQ 265

Query: 1575 CEPGY----TLTTSG-CIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
            CEPG+    TL  SG C++  +   PG     S C     +  +G+          C C+
Sbjct: 266  CEPGFRLDRTLGLSGVCVDMDECLVPGSCPEHSVC----TNHVKGF---------TCECE 312

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSG 1689
              +   +  A C+     A G   ++C + T  C    G     CD C + Y  V  N  
Sbjct: 313  SGYLMDDLKAHCIDVDECALG---ATCPSGT-NCVNTQGSF--YCD-CGHGYHAV--NGT 363

Query: 1690 CEVVYD 1695
            C+ ++D
Sbjct: 364  CQGMFD 369


>SB_54230| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1359

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 2/41 (4%)

Query: 1310 CPEKRSRC--SSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  ++C  SS PC NGA CS+L  TY C    G+TGK C
Sbjct: 913  CEKGINKCIPSSNPCKNGATCSNLHGTYTCTYATGYTGKHC 953



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + CS ++PC NGA C +L   Y C C  G TGK C
Sbjct: 834  CEKDVNECSQNSPCRNGATCLNLPGAYTCTCASGFTGKHC 873



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 16/28 (57%), Positives = 18/28 (64%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            PC N A CS+L  TY C C  G+TGK C
Sbjct: 1027 PCKNRATCSNLHGTYTCTCATGYTGKHC 1054



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 46/162 (28%), Positives = 61/162 (37%), Gaps = 17/162 (10%)

Query: 1511 CQSRAD-CML-SICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC-ELGPC-GAARCV 1563
            C++  D C + S C   + C     + TC C  G  G  C   V+ C +  PC   A C+
Sbjct: 795  CETDIDECKITSSCKNGATCTNLHGTYTCICATGYKGEHCEKDVNECSQNSPCRNGATCL 854

Query: 1564 PDQTPKGYSCACEPGYT-LTTSGCIESGKEE--CPGGWWGGSACGP--CACDVTRGYHPH 1618
                P  Y+C C  G+T       I+  K +  C  G    ++ G   C+C        H
Sbjct: 855  --NLPGAYTCTCASGFTGKHCEKDIDECKVQNPCRNGATCINSIGDYRCSCCPPCFTGQH 912

Query: 1619 CNKENGKCHCKENHYKPEGTAECL--PCQC-YAAGSENSSCE 1657
            C K   KC    N  K   T   L     C YA G     CE
Sbjct: 913  CEKGINKCIPSSNPCKNGATCSNLHGTYTCTYATGYTGKHCE 954



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 7/64 (10%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL-GPC-GAARCVPDQTPKGYSCACE 1576
            C   + C     + TCTC  G  G  C   +  C++  PC   A C+   +   Y C+C 
Sbjct: 1028 CKNRATCSNLHGTYTCTCATGYTGKHCEKDIDECKVQNPCRNGATCI--NSMGDYRCSCP 1085

Query: 1577 PGYT 1580
            PG+T
Sbjct: 1086 PGFT 1089



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 8/105 (7%)

Query: 1248 PTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVG---CISDFYIDHKFIDLNSYVADN 1304
            PT  C++    +  L+  G P++   + ++  D  G   C +      K         D 
Sbjct: 695  PTPRCNK----SDTLECVGAPSVNYVYTLQEDDPCGSHLCKNGATCTSKLGKYRCSCPDG 750

Query: 1305 GTLAGCPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
             T   C    + C  S PC N   C + + +Y C C  G TGK+C
Sbjct: 751  LTGRHCETDLNECKPSNPCRNDGTCVNTYGSYSCACPTGLTGKNC 795



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 5/39 (12%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079
            S++C CP G TG NCET + +  C++    S C++G+ C
Sbjct: 781  SYSCACPTGLTGKNCETDIDE--CKIT---SSCKNGATC 814



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C  ++ C NGA C++L  TY C C  G+ G+ C
Sbjct: 795  CETDIDECKITSSCKNGATCTNLHGTYTCICATGYKGEHC 834



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 8/64 (12%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            ++TC C  GFTG +CE  + +  C+V      CR+G+ C+    G   C  C     +T 
Sbjct: 859  AYTCTCASGFTGKHCEKDIDE--CKVQNP---CRNGATCI-NSIGDYRCSCC--PPCFTG 910

Query: 1101 AVCE 1104
              CE
Sbjct: 911  QHCE 914



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 42/162 (25%), Positives = 57/162 (35%), Gaps = 27/162 (16%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL-GPC-GAARCVPDQTPKGYSCACE 1576
            C     CV ++ S +C C  G  G  C   +  C++   C   A C        Y+C C 
Sbjct: 769  CRNDGTCVNTYGSYSCACPTGLTGKNCETDIDECKITSSCKNGATCT--NLHGTYTCICA 826

Query: 1577 PGYTLTTSGCIESGKEECP--GGWWGGSAC----GPCACDVTRGY-HPHCNKENGKCHCK 1629
             GY      C E    EC        G+ C    G   C    G+   HC K+  +C  +
Sbjct: 827  TGY--KGEHC-EKDVNECSQNSPCRNGATCLNLPGAYTCTCASGFTGKHCEKDIDECKVQ 883

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPGV 1669
                     A C+     + G    SC     TGQ HC  G+
Sbjct: 884  N---PCRNGATCI----NSIGDYRCSCCPPCFTGQ-HCEKGI 917



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 15/40 (37%), Positives = 18/40 (45%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCS-SAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +    C    PC NGA C +    Y C C  G TG+ C
Sbjct: 1054 CEKDIDECKVQNPCRNGATCINSMGDYRCSCPPGFTGQHC 1093



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 32/113 (28%), Positives = 43/113 (38%), Gaps = 13/113 (11%)

Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACEL-GPC-GAARCVPDQTPKGYSCA 1574
            S C   + C+    + TCTC +G  G  C   +  C++  PC   A C+        SC 
Sbjct: 845  SPCRNGATCLNLPGAYTCTCASGFTGKHCEKDIDECKVQNPCRNGATCINSIGDYRCSC- 903

Query: 1575 CEPGYT-----LTTSGCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNK 1621
            C P +T        + CI S    C  G    +  G   C    GY   HC K
Sbjct: 904  CPPCFTGQHCEKGINKCIPS-SNPCKNGATCSNLHGTYTCTYATGYTGKHCEK 955



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 5/40 (12%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV 1080
            ++TC C  G+TG +CE  + +  C+V      CR+G+ C+
Sbjct: 1040 TYTCTCATGYTGKHCEKDIDE--CKVQNP---CRNGATCI 1074



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 4/67 (5%)

Query: 1042 FTCQCPEGFTGVNCETILT--KASCEVDGDGSICRSGSQCVARREGGILCQGC--SIDAA 1097
            + C CP+G TG +CET L   K S     DG+   +          G+  + C   ID  
Sbjct: 743  YRCSCPDGLTGRHCETDLNECKPSNPCRNDGTCVNTYGSYSCACPTGLTGKNCETDIDEC 802

Query: 1098 YTTAVCE 1104
              T+ C+
Sbjct: 803  KITSSCK 809


>SB_33876| Best HMM Match : EGF (HMM E-Value=2.4e-08)
          Length = 164

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 1/39 (2%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355
            C+S PC NGA C+D  + Y C C  G TG +C ++ G P
Sbjct: 5    CASDPCQNGATCNDGLNNYTCACISGFTGTNC-ETIGKP 42



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 12/20 (60%), Positives = 15/20 (75%)

Query: 1039 VTSFTCQCPEGFTGVNCETI 1058
            + ++TC C  GFTG NCETI
Sbjct: 20   LNNYTCACISGFTGTNCETI 39


>SB_3578| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 355

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 1310 CPEK--RSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CP+    + CSS PC NGA CS     Y C C  G+ G+DC
Sbjct: 312  CPDNVGANPCSSNPCRNGATCSSNEGQYKCKCPPGYGGRDC 352


>SB_58129| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 82

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 1644 CQCYAAGSENSS--CEAATGQCHCRPGVIGRACDAC 1677
            C C+ AG+ N+S  C+   GQC C+  V GR CD C
Sbjct: 46   CGCHGAGTVNASDVCDKLDGQCPCKQAVTGRTCDTC 81


>SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 4232

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/32 (53%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSSAPC NG  C+ +   Y C C  G TG DC
Sbjct: 21   CSSAPCQNGGTCTVVSGGYSCTCLPGFTGNDC 52


>SB_48589| Best HMM Match : EGF (HMM E-Value=2e-19)
          Length = 112

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 14/39 (35%), Positives = 23/39 (58%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C S+PC NG  C++  + + C+C+ G+ GK C
Sbjct: 34   CESEIDECESSPCLNGGTCTNHVNYFHCECRAGYAGKQC 72



 Score = 42.3 bits (95), Expect = 0.005
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+S+PC NG+ C D  + Y C C  G++G  C
Sbjct: 72   CQTDIDECASSPCLNGSTCEDGVNGYTCSCVVGYSGPQC 110



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 7/75 (9%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPD 1565
            C+S  D C  S C     C    +   C C AG  G QC   +  C   PC   + C  +
Sbjct: 34   CESEIDECESSPCLNGGTCTNHVNYFHCECRAGYAGKQCQTDIDECASSPCLNGSTC--E 91

Query: 1566 QTPKGYSCACEPGYT 1580
                GY+C+C  GY+
Sbjct: 92   DGVNGYTCSCVVGYS 106



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 25/95 (26%), Positives = 30/95 (31%), Gaps = 9/95 (9%)

Query: 1534 SSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT--LTTSGCI 1587
            S  C C+AG  G +C   +  CE  PC     C        + C C  GY      +   
Sbjct: 20   SCACLCKAGFTGLECESEIDECESSPCLNGGTCT--NHVNYFHCECRAGYAGKQCQTDID 77

Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNK 1621
            E     C  G           C    GY  P C K
Sbjct: 78   ECASSPCLNGSTCEDGVNGYTCSCVVGYSGPQCGK 112



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 1/39 (2%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548
            CQ+  D C  S C   S C    +  TC+C  G  GPQC
Sbjct: 72   CQTDIDECASSPCLNGSTCEDGVNGYTCSCVVGYSGPQC 110


>SB_32722| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 603

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 41/141 (29%), Positives = 50/141 (35%), Gaps = 26/141 (18%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA--CELGPC-GAARCVPDQTPKGYSC 1573
            C  + C   + CV +  S  C C AG  GP C +   C   PC     CVP +   GY C
Sbjct: 280  CHPNPCHNGATCVATDSSFDCDCVAGWTGPLCQTRQYCIPNPCQNGGTCVPQE--NGYRC 337

Query: 1574 ACEPGYTLTTSGCIESGKEECPGGWWGGSACGP------CAC-----------DVTRGYH 1616
             C+  Y    + C E      P     G  C        CAC           D      
Sbjct: 338  TCQANY--EGNDC-ERANPCSPNPCRNGGTCSEMNNAAVCACGVQFEGNQCEIDKCAKCD 394

Query: 1617 PHCNKENGKCHCKENHYKPEG 1637
             H    NGKC C E  Y+ +G
Sbjct: 395  MHATCRNGKCVCMEG-YEGDG 414



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 49/196 (25%), Positives = 60/196 (30%), Gaps = 20/196 (10%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS-ACELGPCGAARCVPDQTPK 1569
            C+ R+ C  + C     CV       C C  G  G  C +  C   PC       ++   
Sbjct: 170  CEERSICFSNPCLHGGSCVDEMYGFRCNCPIGYNGVTCQNHVCRPNPCQNGGSCLEEGGL 229

Query: 1570 GYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCAC-DVTRGYHPHCNKENGKCHC 1628
            G  C C+ GY      C       C          G C C D   G    CNK    CH 
Sbjct: 230  G-RCICQMGY--HGQHCENDRCRFCSVN--ADCILGHCVCKDGYHGDGKTCNK--NVCHP 282

Query: 1629 KENHYKPE--GTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686
               H       T     C C  AG     C+     C   P   G  C    N Y     
Sbjct: 283  NPCHNGATCVATDSSFDCDC-VAGWTGPLCQTRQ-YCIPNPCQNGGTCVPQENGY----- 335

Query: 1687 NSGCEVVYDG--CPRS 1700
               C+  Y+G  C R+
Sbjct: 336  RCTCQANYEGNDCERA 351



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 46/176 (26%), Positives = 63/176 (35%), Gaps = 21/176 (11%)

Query: 1530 TSWDSSTCTCEAGRVGPQC--VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCI 1587
            TS     CTC  G  G  C  ++ C   PC  A    ++    Y C C  G+   T  C 
Sbjct: 114  TSVTGYQCTCREGFKGFDCEEINLCVPNPCKNAGTCTEKGGGRYDCTCPIGFKGVT--CE 171

Query: 1588 ESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCY 1647
            E           GGS    C  D   G+  +C        C +NH        C P  C 
Sbjct: 172  ERSICFSNPCLHGGS----CV-DEMYGFRCNCPIGYNGVTC-QNHV-------CRPNPCQ 218

Query: 1648 AAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAG 1703
              GS     E   G+C C+ G  G+ C+     +  V  N+ C + +  C   + G
Sbjct: 219  NGGS--CLEEGGLGRCICQMGYHGQHCENDRCRFCSV--NADCILGHCVCKDGYHG 270



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 16/44 (36%), Positives = 22/44 (50%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355
            E+RS C S PC +G  C D    + C+C  G+ G  C +    P
Sbjct: 171  EERSICFSNPCLHGGSCVDEMYGFRCNCPIGYNGVTCQNHVCRP 214



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 3/52 (5%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC--ADSTGP-PWRFGG 1360
            + R  C   PC NG  C    + Y C C+  + G DC  A+   P P R GG
Sbjct: 312  QTRQYCIPNPCQNGGTCVPQENGYRCTCQANYEGNDCERANPCSPNPCRNGG 363



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 14/32 (43%), Positives = 17/32 (53%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C   PC+NGA C     ++ CDC  G TG  C
Sbjct: 280  CHPNPCHNGATCVATDSSFDCDCVAGWTGPLC 311



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 5/68 (7%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSA--CELGPC-GAARCVPDQT 1567
            CQ+R  C+ + C     CV   +   CTC+A   G  C  A  C   PC     C   + 
Sbjct: 311  CQTRQYCIPNPCQNGGTCVPQENGYRCTCQANYEGNDCERANPCSPNPCRNGGTC--SEM 368

Query: 1568 PKGYSCAC 1575
                 CAC
Sbjct: 369  NNAAVCAC 376



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            S C   PC NG +C+ + + Y C C  G  G  C
Sbjct: 21   SFCEPVPCQNGGQCTVVPNGYECTCSPGFMGTHC 54



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 13/37 (35%), Positives = 19/37 (51%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E+ + CS  PC NG  CS++ +  +C C     G  C
Sbjct: 349  ERANPCSPNPCRNGGTCSEMNNAAVCACGVQFEGNQC 385



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 1315 SRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCAD 1350
            ++C   PC NG  C+       Y C C+EG  G DC +
Sbjct: 97   NKCHPNPCRNGGMCTGTTSVTGYQCTCREGFKGFDCEE 134


>SB_12742| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1077

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 60/210 (28%), Positives = 79/210 (37%), Gaps = 45/210 (21%)

Query: 1511 CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQCVSACELGP---CGA-ARC 1562
            C    +C+LS   C  +S C  +  S TC C  G  ++  +CV   E      C A +RC
Sbjct: 354  CNDIDECVLSAPNCSSHSYCSNTMGSYTCRCHVGFIKLNGECVDLNECQKHFYCPATSRC 413

Query: 1563 VPDQTPKGYSCACEPGYTLTTSGCIE--------------------SGKEE--CPGGWWG 1600
            V   T   Y C C  GY    S CI+                     G  E  C  G++G
Sbjct: 414  V--NTLGSYKCRCLEGYHSAGSSCIDIDECKTSAHNCHANATCVNKMGSYECVCKEGYFG 471

Query: 1601 -GSACGPCACDVTR-----GYHPHCNKENG--KCHCKENHYKPEGTAECL-PCQCYAAGS 1651
             G+ C   AC  TR          C  EN   KC CK  +     T E +  CQ   +  
Sbjct: 472  NGTHCEVDAC-FTRPSRLCDKDAVCRLENNAIKCMCKAGYTGDGITCEDVNECQLPGSCH 530

Query: 1652 ENSSCEAATGQ--CHCRPGVIGRACDACAN 1679
             +++C    G   C C  G IG   D C +
Sbjct: 531  VHATCANTNGSHVCTCNKGFIGEG-DLCTD 559


>SB_11540| Best HMM Match : EGF (HMM E-Value=1.5e-25)
          Length = 103

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/34 (50%), Positives = 21/34 (61%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C S PC NGA C+D  + Y C CK G+TG  C
Sbjct: 67   NECQSNPCLNGATCTDHVNGYTCSCKLGYTGIVC 100



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/34 (50%), Positives = 21/34 (61%)

Query: 1315 SRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + C S PC NGA C+D  + Y C CK G+TG  C
Sbjct: 3    NECQSNPCLNGATCTDHVNGYTCKCKLGYTGIVC 36



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 12/28 (42%), Positives = 16/28 (57%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYIC 1337
            C +  + C S PC NGA C+D  + Y C
Sbjct: 36   CQQDINECQSNPCLNGATCTDHVNGYTC 63



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 1/48 (2%)

Query: 1533 DSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580
            + +TCT          ++ C+  PC       D    GY+C+C+ GYT
Sbjct: 50   NGATCTDHVNGYTCSYINECQSNPCLNGATCTDHV-NGYTCSCKLGYT 96



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 4/62 (6%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  + C   + C    +  TC C+ G  G  C   ++ C+  PC       D    GY+
Sbjct: 4    ECQSNPCLNGATCTDHVNGYTCKCKLGYTGIVCQQDINECQSNPCLNGATCTDHV-NGYT 62

Query: 1573 CA 1574
            C+
Sbjct: 63   CS 64


>SB_45954| Best HMM Match : VWA (HMM E-Value=4e-26)
          Length = 715

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/32 (53%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            CSSAPC NG  C+ +   Y C C  G TG DC
Sbjct: 28   CSSAPCQNGGTCTVVSGGYSCACLPGFTGNDC 59



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 21/74 (28%), Positives = 31/74 (41%)

Query: 1276 VKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTY 1335
            V+ KD  G  S+ +    +  LNS V       G    +  C++  C NG  C+     +
Sbjct: 640  VELKDLTGVDSNVFTTTSYDGLNSLVESIRNAVGNAPLKVVCNANACKNGGTCNVYGVGF 699

Query: 1336 ICDCKEGHTGKDCA 1349
             C C    TG DC+
Sbjct: 700  NCTCPIQWTGADCS 713


>SB_5527| Best HMM Match : EGF_CA (HMM E-Value=1e-26)
          Length = 83

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 11/80 (13%)

Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAGR--VGPQC--VSACELGP--CGA-ARCVPDQ 1566
            +C L+I  CP    CV +  S TC C+ G   V   C  +  C LG   C A A CV + 
Sbjct: 4    ECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCVNND 63

Query: 1567 TPKGYSCACEPGYTLTTSGC 1586
                Y+C C+PG+TL  + C
Sbjct: 64   G--SYTCRCKPGFTLVYNKC 81


>SB_33579| Best HMM Match : Laminin_G_2 (HMM E-Value=3.2e-34)
          Length = 1071

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 1281 FVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC- 1339
            FVGC+ D  I    I   S +   G   G     + C   PC NG  C   ++ Y CDC 
Sbjct: 344  FVGCMKDVKIRGVKIRDQSVIRYRGPKFGVCPLENYCFPNPCLNGGVCHIWYNKYTCDCY 403

Query: 1340 KEGHTGKDC 1348
            K  +TG  C
Sbjct: 404  KTFYTGSTC 412


>SB_30923| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 642

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 3/73 (4%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVS--ACELGPC-GAARCVPDQT 1567
            CQ R  C    C     CV    +  C C  G +G  C    AC   PC     C    T
Sbjct: 32   CQERNYCSSMPCLNGGSCVEIPGAFKCGCPFGFLGTVCEERDACHPNPCKNGGTCTRSDT 91

Query: 1568 PKGYSCACEPGYT 1580
              G+ C C+ G+T
Sbjct: 92   ESGFVCVCKEGFT 104



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 1305 GTLAGCPEKRSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDC 1348
            G L    E+R  C   PC NG  C  SD    ++C CKEG TG+ C
Sbjct: 63   GFLGTVCEERDACHPNPCKNGGTCTRSDTESGFVCVCKEGFTGEHC 108



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 3/52 (5%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC--ADSTGP-PWRFGG 1360
            ++R+ CSS PC NG  C ++   + C C  G  G  C   D+  P P + GG
Sbjct: 33   QERNYCSSMPCLNGGSCVEIPGAFKCGCPFGFLGTVCEERDACHPNPCKNGG 84



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/38 (36%), Positives = 19/38 (50%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            C+S PC NG  C +     +C CK   TG  C + + P
Sbjct: 371  CTSNPCQNGGTCMNDKGKAVCRCKGKWTGVTCRECSCP 408


>SB_27599| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2937

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 15/32 (46%), Positives = 21/32 (65%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S PC NG  C D  ++Y+C C  G+TG +C
Sbjct: 137  CASEPCLNGGACVDGANSYLCSCTAGYTGINC 168



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  S C     C+    + +C C  G +GP C   V  C   PC     CV       Y
Sbjct: 98   ECAASPCLNDGTCIDGPGNYSCICSTGFLGPTCEINVDDCASEPCLNGGACV--DGANSY 155

Query: 1572 SCACEPGYT 1580
             C+C  GYT
Sbjct: 156  LCSCTAGYT 164



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 25/77 (32%), Positives = 31/77 (40%), Gaps = 10/77 (12%)

Query: 1041 SFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTT 1100
            +++C C  GF G  CE  +   + E       C +G  CV     G     CS  A YT 
Sbjct: 116  NYSCICSTGFLGPTCEINVDDCASEP------CLNGGACV----DGANSYLCSCTAGYTG 165

Query: 1101 AVCELRARSFPVSSFLT 1117
              CE   R F V S  T
Sbjct: 166  INCETAIRGFLVQSTKT 182



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 12/32 (37%), Positives = 15/32 (46%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+++PC N   C D    Y C C  G  G  C
Sbjct: 99   CAASPCLNDGTCIDGPGNYSCICSTGFLGPTC 130


>SB_42661| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1717

 Score = 43.2 bits (97), Expect = 0.003
 Identities = 53/198 (26%), Positives = 69/198 (34%), Gaps = 25/198 (12%)

Query: 1517 CMLSICPPYSKC-------VTSWDSSTCT-CEAGRVGPQCVSACELGPCGAARCVPDQTP 1568
            C ++ CP    C        T+ D+  CT C  G +GP C   C  G   A  CV D   
Sbjct: 1456 CHITDCPGTPNCFDRGFCNTTNRDTPACTDCVKGWMGPACNDPCVHGREVAGSCVCDPCY 1515

Query: 1569 KGYSCACE-PGYTLTTSGCIESGKEEC---PGGWWGGSACGPCAC---DVTRGYHPHCNK 1621
             G  C  E  G+      C+E GK +C    G  + G  C    C   D     +  CN 
Sbjct: 1516 TGSGCQSECSGH----GECVE-GKCKCNEAAGDAYVGVNCELPGCPGRDGNCNGNGFCNL 1570

Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAAT-GQCHCRPGVIGRACD-ACAN 1679
            +  KC C           + L C      S    C      +C C P   G  C+  C N
Sbjct: 1571 KLQKCECYPGW--AGDACDKLDCPGSPPCSGQGECSNTNPRRCQCFPKWGGEKCEIPCLN 1628

Query: 1680 AYAEVTPNS-GCEVVYDG 1696
             Y     +   C+  Y G
Sbjct: 1629 GYNYGNASDCVCDACYSG 1646



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 48/168 (28%), Positives = 64/168 (38%), Gaps = 36/168 (21%)

Query: 1509 DGCQSRADCMLSI-CPPYSKCVTSWDSSTCT-CEAGRVGPQCVSACELGPCGAARCVPDQ 1566
            DGC+   DC  +  C     C TS+D   CT C  G +G  C   C  G       VP  
Sbjct: 1323 DGCEI-PDCPGNPDCAGRGHCNTSFDPPRCTNCSQGWMGQACEDLCVHGTQ-----VPMD 1376

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
            +    +C C+  +T    GC      EC G   G    G CACD   G+     +  G  
Sbjct: 1377 SG---NCQCDACFT--GRGC----NVECSGH--GQCVNGACACDTLAGWRGSLCEVPG-- 1423

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
             C     K     +C         S + +C++A  +C C PG  G  C
Sbjct: 1424 -CAGVDGK-----DC---------SGHGTCDSANHKCICDPGWSGIGC 1456


>SB_14079| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 546

 Score = 43.2 bits (97), Expect = 0.003
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 7/84 (8%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYS 1572
            +C  S C     CV   +  +CTC AG  G  C   +  C   PC       D    G++
Sbjct: 182  ECKSSPCNNGRTCVDGINRYSCTCAAGFTGTNCETDIDECAGNPCANGGTCKDGI-NGFT 240

Query: 1573 CACEPGYTLTTSGCIESGKEECPG 1596
            C C  GY+ +T  C E   +EC G
Sbjct: 241  CECPVGYSGST--C-EIDIDECAG 261



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 10/77 (12%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  FTC+CP G++G  CE  + + +      G+ C +G  C    + GI    C     Y
Sbjct: 236  INGFTCECPVGYSGSTCEIDIDECA------GNPCANGGTC----KDGINGFTCECHVGY 285

Query: 1099 TTAVCELRARSFPVSSF 1115
            + + CE+      V+SF
Sbjct: 286  SGSTCEIEGLILSVNSF 302



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 7/57 (12%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG---DGMLSF 1366
            C S+PC NG  C D  + Y C C  G TG +C     +  G P   GG   DG+  F
Sbjct: 183  CKSSPCNNGRTCVDGINRYSCTCAAGFTGTNCETDIDECAGNPCANGGTCKDGINGF 239



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  ++C C  GFTG NCET + + +      G+ C +G  C    + GI    C     Y
Sbjct: 198  INRYSCTCAAGFTGTNCETDIDECA------GNPCANGGTC----KDGINGFTCECPVGY 247

Query: 1099 TTAVCEL 1105
            + + CE+
Sbjct: 248  SGSTCEI 254



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 7/68 (10%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA----DSTGPPWRFGG- 1360
            T   C      C+  PC NG  C D  + + C+C  G++G  C     +  G P   GG 
Sbjct: 210  TGTNCETDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTCEIDIDECAGNPCANGGT 269

Query: 1361 --DGMLSF 1366
              DG+  F
Sbjct: 270  CKDGINGF 277



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C+  PC NG  C D  + + C+C  G++G  C
Sbjct: 252  CEIDIDECAGNPCANGGTCKDGINGFTCECHVGYSGSTC 290



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 1044 CQCPEGFTGVNCET---ILTKASCEVDGD----GSICRSGSQCVARREGGILCQGCSIDA 1096
            C CP GF+G  CE+    +T  +  +D D     S C +G  CV     GI    C+  A
Sbjct: 152  CHCPAGFSGDKCESKLLYITNLTPLIDNDDECKSSPCNNGRTCV----DGINRYSCTCAA 207

Query: 1097 AYTTAVCE 1104
             +T   CE
Sbjct: 208  GFTGTNCE 215



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 5/77 (6%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C++  D C  + C     C    +  TC C  G  G  C   +  C   PC       D 
Sbjct: 214  CETDIDECAGNPCANGGTCKDGINGFTCECPVGYSGSTCEIDIDECAGNPCANGGTCKDG 273

Query: 1567 TPKGYSCACEPGYTLTT 1583
               G++C C  GY+ +T
Sbjct: 274  I-NGFTCECHVGYSGST 289


>SB_7343| Best HMM Match : EGF (HMM E-Value=0)
          Length = 1233

 Score = 43.2 bits (97), Expect = 0.003
 Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 18/168 (10%)

Query: 1536 TCTCEAGRVGPQCVSA--CEL-GPCG----AARCVPDQTPKGYSCACEPGYTLTTSGCIE 1588
            +CTC +G  G  C     CE   PC       R +      GY+C C PGY  T   C E
Sbjct: 278  SCTCVSGYTGRNCTERDLCEPENPCANGGTCQRTIGSDGSLGYNCTCAPGYLGT--NCTE 335

Query: 1589 SGKEECPGGWWGGSAC-GPCACDVTRGYHPHCNKENGKCHCKE-NHYKPEGTAECLPCQC 1646
                E       G  C      D + GY+  C       +C E N  +P       PC  
Sbjct: 336  RNLCEPVNPCINGGTCKRTVGSDGSPGYNCTCAPGYLGTNCTERNLCEPVN-----PCAN 390

Query: 1647 YAAGSENSSCEAATG-QCHCRPGVIGRACDACANAYAEV-TPNSGCEV 1692
                      + + G  C C  G  G  C     + + V TP+S  ++
Sbjct: 391  GGTCKRTVGSDGSAGYNCTCIEGFTGENCSEITPSSSSVPTPSSSSDI 438



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 11/72 (15%)

Query: 1312 EKRSRCSSAPCYNGAECSD----LWDTYICDCKEGHTGKDCA----DSTGPPWRFGG--- 1360
            E+ + C  +PC N A C D    L D Y C C  G TGK+C     D    P   GG   
Sbjct: 167  EELNSCLRSPCQNQATCLDINAGLRDAYNCSCVPGFTGKNCEINIDDCASRPCLNGGLCV 226

Query: 1361 DGMLSFNPLLRP 1372
            DG+ S++ L +P
Sbjct: 227  DGVNSYSCLCQP 238



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 46/171 (26%), Positives = 59/171 (34%), Gaps = 19/171 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCV----SACELGPC---GAA-RCVP-DQ 1566
            DC    C     CV   +S +C C+    G  C     + C+  PC   G   R V  D 
Sbjct: 213  DCASRPCLNGGLCVDGVNSYSCLCQPDINGNNCEIVTPNRCQPNPCENGGTCDRTVGNDG 272

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSAC-GPCACDVTRGYHPHCNKENGK 1625
            +   YSC C  GY  T   C E    E       G  C      D + GY+  C      
Sbjct: 273  SRSNYSCTCVSGY--TGRNCTERDLCEPENPCANGGTCQRTIGSDGSLGYNCTCAPGYLG 330

Query: 1626 CHCKE-NHYKPEGTAECLPCQCYAAGSENSSCEAATG-QCHCRPGVIGRAC 1674
             +C E N  +P       PC            + + G  C C PG +G  C
Sbjct: 331  TNCTERNLCEPVN-----PCINGGTCKRTVGSDGSPGYNCTCAPGYLGTNC 376



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 75/325 (23%), Positives = 119/325 (36%), Gaps = 38/325 (11%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQ-----CVARR-EGGILCQ-GCSI 1094
            + C+CP G+ G +C  I        +G   I  + SQ     C+    + G+ C+   SI
Sbjct: 709  YDCKCPSGYQGKSCTLISACVGDPCNGGRCIVSNSSQPQNHVCLCPYGKAGVSCEHDISI 768

Query: 1095 DAAYTTAVCELRARSFPVSSFLTFPGLKRRH-RIHLKLKFATQTTSGLLLYNG--RYNER 1151
                 T    L   +  +      PG       +  ++         LLLY+   RY   
Sbjct: 769  SVPGFTM---LHGYASYIQYATPTPGASHFDITMQFRVDDPIAWNDALLLYSSQDRYLGG 825

Query: 1152 HDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMI 1211
             DF+AL L   +        +   ++LG G + I          WHTV          + 
Sbjct: 826  GDFIALGLKDGQ--------ILLQYNLGSGLARIRSCSLNKTQDWHTVTAGRSGPEGYVY 877

Query: 1212 LDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIP 1271
             D+C+KV   +     GL      F   V     E+PT     ++D     + G L  + 
Sbjct: 878  ADNCEKVRGSSEGNLQGLDLYAPLFIGGVHDLS-ELPT-----YVDFKSGFR-GNLYGMA 930

Query: 1272 SSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA--PCYNGAECS 1329
              F   N+++   +S   +  + +   S   + G+  G  E  + C S   PC NG  C+
Sbjct: 931  IRFS--NQEYWRNLS--LLQTQGV---SERVEAGSNIG-NESYNECISQTPPCLNGGNCT 982

Query: 1330 DLWDTYICDCKEGHTGKDCADSTGP 1354
                TY+C C  G  G  C   + P
Sbjct: 983  RHAATYVCRCLPGWRGLYCGSRSIP 1007



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 7/71 (9%)

Query: 1515 ADCMLSICPPYSKCVTSWDSS---TCTCEAGRVGPQC--VSACELGPCGAARCVPDQT-- 1567
            A C+ + C     C    D      C C +G  G  C  +SAC   PC   RC+   +  
Sbjct: 686  APCVNNPCHNGGTCTPDGDDPHDYDCKCPSGYQGKSCTLISACVGDPCNGGRCIVSNSSQ 745

Query: 1568 PKGYSCACEPG 1578
            P+ + C C  G
Sbjct: 746  PQNHVCLCPYG 756



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S PC NG  C D  ++Y C C+    G +C
Sbjct: 214  CASRPCLNGGLCVDGVNSYSCLCQPDINGNNC 245



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 3/35 (8%)

Query: 1317 CSSAPCYNGAECSDLWDT---YICDCKEGHTGKDC 1348
            C + PC+NG  C+   D    Y C C  G+ GK C
Sbjct: 688  CVNNPCHNGGTCTPDGDDPHDYDCKCPSGYQGKSC 722



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 1310 CPEKRSRCSSA-PCYNGAEC-----SDLWDTYICDCKEGHTGKDCADST 1352
            C E R+ C    PC NG  C     SD    Y C C EG TG++C++ T
Sbjct: 376  CTE-RNLCEPVNPCANGGTCKRTVGSDGSAGYNCTCIEGFTGENCSEIT 423



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 6/42 (14%)

Query: 1315 SRCSSAPCYNGAECSDLW------DTYICDCKEGHTGKDCAD 1350
            +RC   PC NG  C            Y C C  G+TG++C +
Sbjct: 251  NRCQPNPCENGGTCDRTVGNDGSRSNYSCTCVSGYTGRNCTE 292


>SB_5020| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 687

 Score = 43.2 bits (97), Expect = 0.003
 Identities = 51/187 (27%), Positives = 64/187 (34%), Gaps = 34/187 (18%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574
            C   +KC     S  CTC  G  G   +C  +  C  G   C   ARC  + T   Y C 
Sbjct: 326  CDKNAKCNNIIGSYHCTCNPGFSGDGRECTDIDECVTGDHTCDKNARC--NNTIGSYHCT 383

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634
            C PG++     C +   +EC          G   CD     +  CN   G  HC+ N   
Sbjct: 384  CNPGFSGDGRECTDI--DEC--------VTGDHTCD----KNARCNNTIGSYHCRCNPGF 429

Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC---DACANAYAE 1683
                 EC        G     +N+ C    G   C C PG    GR C   D C      
Sbjct: 430  SGDGRECTDIDECVTGDHTCDKNARCNNTIGSYHCTCNPGFSGDGRECTDMDECVTGDHT 489

Query: 1684 VTPNSGC 1690
               N+ C
Sbjct: 490  CDKNAKC 496



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 48/196 (24%), Positives = 65/196 (33%), Gaps = 32/196 (16%)

Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELG--PCGA-AR 1561
            C    +C      C   +KC  +  S  CTC  G  G    C  +  C  G   C   A+
Sbjct: 108  CSETDECSAGNHTCDKNAKCNNTIGSYHCTCNPGFSGDGRNCTDIDECVTGNHTCDKNAK 167

Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNK 1621
            C  +     Y C C PG++     C +   +EC          G   CD     +  CN 
Sbjct: 168  C--NNIIGSYHCMCNPGFSKDGRECTDI--DEC--------VTGDHTCD----KNARCNN 211

Query: 1622 ENGKCHCKENHYKPEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVIGRACD 1675
              G  HC  N         C        G     +N+ C    G   C C PG  G   +
Sbjct: 212  IIGSYHCMCNPGFSGDGRNCTDIDECVTGDHTCDKNARCGNIIGSHHCICNPGFSGDGKN 271

Query: 1676 ACANAYAEVTPNSGCE 1691
             C +    VT +  C+
Sbjct: 272  -CTDIDECVTGDHTCD 286



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 46/187 (24%), Positives = 64/187 (34%), Gaps = 34/187 (18%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574
            C   ++C  +  S  CTC  G  G   +C  +  C  G   C   A+C  +     + C 
Sbjct: 449  CDKNARCNNTIGSYHCTCNPGFSGDGRECTDMDECVTGDHTCDKNAKC--NNIIGSHHCT 506

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634
            C PG++     CI+   +EC          G   CD     +  CN   G  HC  N   
Sbjct: 507  CNPGFSGDGRECIDI--DEC--------VTGDHTCD----KNAKCNNIVGSHHCTCNPGF 552

Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVIG-----RACDACANAYAE 1683
                 EC        G     +N+ C    G   C C  G  G     R  D C      
Sbjct: 553  SGNGRECTDIDECGTGDHTCDKNARCNNTIGSYDCMCMSGFYGNSTRCRDIDECKKEKHH 612

Query: 1684 VTPNSGC 1690
             +P++ C
Sbjct: 613  CSPHAIC 619


>SB_37317| Best HMM Match : EGF_CA (HMM E-Value=6.6e-25)
          Length = 86

 Score = 42.7 bits (96), Expect = 0.004
 Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 8/74 (10%)

Query: 1522 CPPY-SKCVTSWDSSTCTCEAGRVGP--QCVSACELGPCGAARCVPD-----QTPKGYSC 1573
            C P  S C  +  S TC+C AG  G    CV   +    GA  C P       T   Y+C
Sbjct: 12   CAPIGSSCTNNAGSFTCSCNAGYAGDGETCVEDIDECSSGAHTCAPSGSTCTNTVGSYTC 71

Query: 1574 ACEPGYTLTTSGCI 1587
            AC  GYT     C+
Sbjct: 72   ACNVGYTGDGETCV 85


>SB_28272| Best HMM Match : EGF (HMM E-Value=2.6e-15)
          Length = 157

 Score = 42.7 bits (96), Expect = 0.004
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 6/70 (8%)

Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570
            C  S C   + C    D+S   CTC  G  G  C   V  C   PC   + C       G
Sbjct: 80   CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKPCGSSPCKNNSTCTNKDENSG 139

Query: 1571 YSCACEPGYT 1580
            Y C C  G+T
Sbjct: 140  YDCTCSTGFT 149



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354
            + +GT A     +  C S+PC N A C++  D   Y C C  G TG DC     P
Sbjct: 66   SSSGTCANSARVKP-CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKP 119



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSACELGPC-GAARCVPDQTP 1568
            C     C ++      +C    +SS+ TC  + RV P     C+  PC   A C   +  
Sbjct: 43   CTEEYICRVNFENNTHRCECPKESSSGTCANSARVKP-----CDSSPCQNNATCTNKEDN 97

Query: 1569 KGYSCACEPGYT 1580
             GY+C C  G+T
Sbjct: 98   SGYNCTCSTGFT 109



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 2/45 (4%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECS--DLWDTYICDCKEGHTGKDC 1348
            T + C  +   C S+PC N + C+  D    Y C C  G T  DC
Sbjct: 109  TGSDCETQVKPCGSSPCKNNSTCTNKDENSGYDCTCSTGFTESDC 153



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 8/65 (12%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            + + C C  GFTG +CET +           S C++ S C  + E       C+    +T
Sbjct: 98   SGYNCTCSTGFTGSDCETQVKPCG------SSPCKNNSTCTNKDENS--GYDCTCSTGFT 149

Query: 1100 TAVCE 1104
             + CE
Sbjct: 150  ESDCE 154


>SB_20457| Best HMM Match : fn3 (HMM E-Value=5.1e-12)
          Length = 1114

 Score = 42.7 bits (96), Expect = 0.004
 Identities = 51/229 (22%), Positives = 85/229 (37%), Gaps = 20/229 (8%)

Query: 1663 CHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPP 1722
            C C PG +G       N +     + G     D C       + W RT  G   +T CP 
Sbjct: 652  CKCGPGFVG-------NGFLCRVESPGLSDK-DFCGPITTQNIKWSRTLKGQTDVTSCPK 703

Query: 1723 GSSGRATRTCDE---TKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVA 1779
              +G A R C E    +D  W  PD+  C +     +++Q   ++  E    T V  +VA
Sbjct: 704  DVTGVARRKCKEQEPDQDASWDTPDLSECISEWALNIKEQ--ALDPSEAV--TSVASKVA 759

Query: 1780 ADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTIL 1839
                T+      +Y  D+     IL  L   E   +  +       D+ + ++++ + IL
Sbjct: 760  N--LTSVTRVEDIYPGDLYAVVDILGLLS--ERAGSSRSSVPQASTDFNKAVVQTASNIL 815

Query: 1840 NVEYEREWKRIREL-TGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIV 1887
              +   +W  I        A  L+   D     +A+S     T+   +V
Sbjct: 816  EAKTINKWSFIPPTKRKRQAGSLMSNLDNVALKMAQSSGSAITAMPNVV 864


>SB_37171| Best HMM Match : EGF (HMM E-Value=2.6e-15)
          Length = 186

 Score = 42.7 bits (96), Expect = 0.004
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 6/70 (8%)

Query: 1517 CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKG 1570
            C  S C   + C    D+S   CTC  G  G  C   V  C   PC   + C       G
Sbjct: 80   CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKPCGSSPCKNNSTCTNKDENSG 139

Query: 1571 YSCACEPGYT 1580
            Y C C  G+T
Sbjct: 140  YDCTCSTGFT 149



 Score = 41.5 bits (93), Expect = 0.009
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354
            + +GT A     +  C S+PC N A C++  D   Y C C  G TG DC     P
Sbjct: 66   SSSGTCANSARVKP-CDSSPCQNNATCTNKEDNSGYNCTCSTGFTGSDCETQVKP 119



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 3/66 (4%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECS--DLWDTYICDCKEGHTGKDC-ADSTGPPWRFGGDG 1362
            T + C  +   C S+PC N + C+  D    Y C C  G T  DC    T   +RF  + 
Sbjct: 109  TGSDCETQVKPCGSSPCKNNSTCTNKDENSGYDCTCSTGFTESDCETQGTISKYRFNAET 168

Query: 1363 MLSFNP 1368
              S  P
Sbjct: 169  GQSGEP 174



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSACELGPC-GAARCVPDQTP 1568
            C     C ++      +C    +SS+ TC  + RV P     C+  PC   A C   +  
Sbjct: 43   CTEEYICRVNFENNTHRCECPKESSSGTCANSARVKP-----CDSSPCQNNATCTNKEDN 97

Query: 1569 KGYSCACEPGYT 1580
             GY+C C  G+T
Sbjct: 98   SGYNCTCSTGFT 109



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 8/65 (12%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            + + C C  GFTG +CET +           S C++ S C  + E       C+    +T
Sbjct: 98   SGYNCTCSTGFTGSDCETQVKPCG------SSPCKNNSTCTNKDENS--GYDCTCSTGFT 149

Query: 1100 TAVCE 1104
             + CE
Sbjct: 150  ESDCE 154


>SB_31622| Best HMM Match : EGF (HMM E-Value=4.2e-09)
          Length = 39

 Score = 42.7 bits (96), Expect = 0.004
 Identities = 16/32 (50%), Positives = 19/32 (59%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C S PC NG  C DL  +Y CDC +G  G +C
Sbjct: 5    CLSTPCLNGGTCVDLVASYRCDCIKGFNGTNC 36


>SB_19665| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 491

 Score = 42.7 bits (96), Expect = 0.004
 Identities = 42/130 (32%), Positives = 54/130 (41%), Gaps = 14/130 (10%)

Query: 1499 NRPTVRENVRDGCQSRADCMLSICPP-YSKCVTSWDSS-TCTCEAGRVGPQCVSACELGP 1556
            N   V E+V  G ++   C    CP   S C    DSS +C C  G  G +C    E   
Sbjct: 111  NMADVSESVYQGFENV--CNNRPCPDDRSTCGIGTDSSHSCLCRPGFEGEKCSDIDECAV 168

Query: 1557 CGAARCVPD----QTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDV 1611
             G + C  +     T   Y+C C+PGYT     C  +  +EC     G S C   A C+ 
Sbjct: 169  SGDSPCDKNAECNNTVGSYTCTCKPGYTGDRKTC--NDIDECAIS--GDSPCDKNAECNN 224

Query: 1612 TRG-YHPHCN 1620
            T G Y   CN
Sbjct: 225  TVGSYTCTCN 234



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 18/116 (15%)

Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQ--C--VSACELG---PCGA-ARCVPDQTPKGY 1571
            S C   ++C  +  S TCTC+ G  G +  C  +  C +    PC   A C  + T   Y
Sbjct: 172  SPCDKNAECNNTVGSYTCTCKPGYTGDRKTCNDIDECAISGDSPCDKNAEC--NNTVGSY 229

Query: 1572 SCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCAC---DVTRGYHPHC 1619
            +C C PGYT     C +     +  + C G     +    C C     T    PHC
Sbjct: 230  TCTCNPGYTGDGKTCDDVNECTTNPDICNGECTNYNGSYTCKCRDKSNTMSQAPHC 285



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 2/33 (6%)

Query: 1320 APCYNGAECSDLWDTYICDCKEGHTG--KDCAD 1350
            +PC   AEC++   +Y C CK G+TG  K C D
Sbjct: 172  SPCDKNAECNNTVGSYTCTCKPGYTGDRKTCND 204



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%)

Query: 1320 APCYNGAECSDLWDTYICDCKEGHT--GKDCAD 1350
            +PC   AEC++   +Y C C  G+T  GK C D
Sbjct: 214  SPCDKNAECNNTVGSYTCTCNPGYTGDGKTCDD 246


>SB_32719| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 604

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 52/194 (26%), Positives = 64/194 (32%), Gaps = 28/194 (14%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKGYSC 1573
            C+ S C     CV    S  C C     G  C  +S C   PC     C    T +G+ C
Sbjct: 196  CLPSPCRNNGTCVNIGASYKCNCPPEFYGKHCEALSKCTPNPCKNDGTCRDISTGRGFVC 255

Query: 1574 ACEPGYTLTTSGCIESG----KEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHC 1628
             C   Y      C           C  G    +     AC    GY   HC + N    C
Sbjct: 256  YCSIAY--LGPNCDRKNLCHPDNPCKNGGTCKTDGSTVACHCKEGYLGSHCEQMN---FC 310

Query: 1629 KENHYKPEGTAECLP------CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYA 1682
              N  K +GT  C P      C C   G    +C+    +C+  P   G  C       A
Sbjct: 311  YGNPCKNKGT--CTPKLDGYECDC-PEGFYGKNCD-GVDRCYPNPCANGATC-----FNA 361

Query: 1683 EVTPNSGCEVVYDG 1696
            E+T    C V Y G
Sbjct: 362  ELTYICQCPVRYMG 375



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 46/181 (25%), Positives = 58/181 (32%), Gaps = 24/181 (13%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC--VSACELGPC-GAARCVPDQTPKGYSCACEPG 1578
            C     C T   +  C C+ G +G  C  ++ C   PC     C P     GY C C  G
Sbjct: 278  CKNGGTCKTDGSTVACHCKEGYLGSHCEQMNFCYGNPCKNKGTCTPKL--DGYECDCPEG 335

Query: 1579 -YTLTTSGCIESGKEECPGG--WWGGSACGPCACDV----TRGYHPHC-----NKE--NG 1624
             Y     G        C  G   +       C C V     R     C     N E  NG
Sbjct: 336  FYGKNCDGVDRCYPNPCANGATCFNAELTYICQCPVRYMGIRCRVDKCDRCDLNAECLNG 395

Query: 1625 KCHCKE----NHYKPEGTAE-CLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
             C C+     N +K   T + C+P  C   G            C C  G  G  C+   +
Sbjct: 396  TCECRSGFVGNGFKCTATEDPCIPNPCENGGICRPGHGGKVFDCSCPSGFDGMRCEVTKS 455

Query: 1680 A 1680
            A
Sbjct: 456  A 456



 Score = 41.1 bits (92), Expect = 0.012
 Identities = 18/44 (40%), Positives = 22/44 (50%)

Query: 1305 GTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            G L    E+ + C   PC N   C+   D Y CDC EG  GK+C
Sbjct: 298  GYLGSHCEQMNFCYGNPCKNKGTCTPKLDGYECDCPEGFYGKNC 341



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 7/63 (11%)

Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061
            C   PCLN   C+ +    N +G +  D V+F      + F C CP+G+ G+NC+ ++ +
Sbjct: 457  CKARPCLNGGICVDLT---NDNGTL-LDGVIF---LNTSDFRCVCPKGYAGINCDKLVLR 509

Query: 1062 ASC 1064
              C
Sbjct: 510  NPC 512



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 35/144 (24%), Positives = 47/144 (32%), Gaps = 16/144 (11%)

Query: 1575 CEPGYTLTTSGCIESG---KEECPGGWWGG-----SACGPCACDVTRGYHPHCNKENGKC 1626
            C P        C+  G   K  CP  ++G      S C P  C                C
Sbjct: 196  CLPSPCRNNGTCVNIGASYKCNCPPEFYGKHCEALSKCTPNPCKNDGTCRDISTGRGFVC 255

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPGVIGRACDACANAYAEV 1684
            +C   +  P    + L C          +C  + +T  CHC+ G +G  C+     Y   
Sbjct: 256  YCSIAYLGPNCDRKNL-CHPDNPCKNGGTCKTDGSTVACHCKEGYLGSHCEQMNFCYGNP 314

Query: 1685 TPNSG-CEVVYDG----CPRSFAG 1703
              N G C    DG    CP  F G
Sbjct: 315  CKNKGTCTPKLDGYECDCPEGFYG 338



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 15/39 (38%), Positives = 16/39 (41%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  K       PC NG  C     T  C CKEG+ G  C
Sbjct: 266  CDRKNLCHPDNPCKNGGTCKTDGSTVACHCKEGYLGSHC 304



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 7/59 (11%)

Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCV-ARREGGILCQG 1091
            RP +    F C CP GF G+ CE  +TK++C+       C +G  CV    + G L  G
Sbjct: 429  RPGHGGKVFDCSCPSGFDGMRCE--VTKSACK----ARPCLNGGICVDLTNDNGTLLDG 481



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 15/33 (45%), Positives = 17/33 (51%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            RC   PC NGA C +   TYIC C   + G  C
Sbjct: 346  RCYPNPCANGATCFNAELTYICQCPVRYMGIRC 378



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 10/75 (13%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGS-----QCVARREG----GILCQGC 1092
            + C CPEGF G NC+ +  +       +G+ C +       QC  R  G       C  C
Sbjct: 328  YECDCPEGFYGKNCDGV-DRCYPNPCANGATCFNAELTYICQCPVRYMGIRCRVDKCDRC 386

Query: 1093 SIDAAYTTAVCELRA 1107
             ++A      CE R+
Sbjct: 387  DLNAECLNGTCECRS 401


>SB_26949| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 92

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 23/68 (33%), Positives = 41/68 (60%), Gaps = 4/68 (5%)

Query: 394 DEDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
           D+ N +L++ IT GN +  F +   N  G+I + + LDF++ + Y L+VS  DSG     
Sbjct: 2   DKSNAQLNFGITEGNVKNTFYV---NTEGVIYLNRSLDFEERKVYNLSVSVEDSGTPKRK 58

Query: 453 AMVQINIT 460
           A+++ N++
Sbjct: 59  AVIEANVS 66



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 16/55 (29%), Positives = 33/55 (60%), Gaps = 1/55 (1%)

Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
           +N+ + + I  GN +  F +++  G + L ++LD+E+ + Y L +  +D G+P R
Sbjct: 4   SNAQLNFGITEGNVKNTFYVNT-EGVIYLNRSLDFEERKVYNLSVSVEDSGTPKR 57


>SB_23501| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 585

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 8/76 (10%)

Query: 1527 KCVTSWDSSTCTCEAGRV--GPQCVSA--CELGP--CGAARCVPDQTPKGYSCACEPGYT 1580
            +CV +  S  C C  G +  G  CV    C + P  CG A+CV   TP  Y C C  G+ 
Sbjct: 15   RCVNTVGSFRCECPIGYMKNGVTCVDKDECMMTPNLCGEAKCV--NTPGSYVCKCNSGFE 72

Query: 1581 LTTSGCIESGKEECPG 1596
                      K+EC G
Sbjct: 73   YNPQTKTCGDKDECKG 88



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 51/190 (26%), Positives = 72/190 (37%), Gaps = 32/190 (16%)

Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAG-RVGPQCVSACELGPC-GAAR----- 1561
            C  + +CM++  +C   +KCV +  S  C C +G    PQ  +  +   C G ++     
Sbjct: 38   CVDKDECMMTPNLCGE-AKCVNTPGSYVCKCNSGFEYNPQTKTCGDKDECKGQSQLCQFG 96

Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNK 1621
            CV       Y C C+PG+TL+          EC       + CG   C  T G + +C  
Sbjct: 97   CV--NLIGSYRCGCQPGFTLSYYWNQCQDVNECQ-----TNPCGGAQCQNTLGSY-YCGC 148

Query: 1622 ENGKCHCKENHYKPEGTAECL----PCQCYAAGSENS--SCEAAT-----GQCHCRPGVI 1670
              G      N    +   EC     PC  Y   + N   SC   +     G  HC     
Sbjct: 149  AQGNI-LAPNRRSCQDINECSMGINPCS-YGCNNNNGGFSCACPSGFYPIGDGHCLSS-F 205

Query: 1671 GRACDACANA 1680
            G AC  CA A
Sbjct: 206  GEACYECALA 215


>SB_21594| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1075

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGD 1361
            C +  + C S PC NG  C++    Y C C  G TG +C   TG   RF  D
Sbjct: 504  CEDDINECQSNPCKNGGTCANGEHKYSCACAPGFTGTNC--DTGKLVRFTSD 553



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 4/49 (8%)

Query: 1537 CTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLT 1582
            C C  G  G +C   ++ C+  PC       +   K YSCAC PG+T T
Sbjct: 493  CHCPEGFSGDKCEDDINECQSNPCKNGGTCANGEHK-YSCACAPGFTGT 540



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSG 1076
            C CPEGF+G  CE  + +       +G  C +G
Sbjct: 493  CHCPEGFSGDKCEDDINECQSNPCKNGGTCANG 525


>SB_33543| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 838

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%)

Query: 1275 QVKNKDFVGCISDFYID-HKFI--DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDL 1331
            + K   FVGC+ +  ID HK     L+     NG  A      +RC   PC N   C   
Sbjct: 338  EYKFPGFVGCMLNLRIDSHKITARHLSKQKYSNGIDATKCATSNRCFPNPCINRGTCWQD 397

Query: 1332 WDTYICDCKEGH-TGKDC 1348
            W ++ CDC   +  GK C
Sbjct: 398  WQSFYCDCSNTYFEGKRC 415



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 38/158 (24%), Positives = 67/158 (42%), Gaps = 17/158 (10%)

Query: 1393 MSIQLKSGLLHYSY---NGETMYLPMA-TLSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448
            ++I+L SG+L Y     NG    L M   L+DG WH +    +  ++ +T+D   R+  +
Sbjct: 254  LNIRLHSGVLMYDVLAPNGSKAELRMGENLNDGEWHSVNASIVPPNVQLTLDDRTRSKFL 313

Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGLLASDVGF--FEGCIQDVRIGTAQSLLNRPTVREN 1506
             + +  +      ++ I      AG  A +  F  F GC+ ++RI  +  +  R   ++ 
Sbjct: 314  NLTSLLLDFSNKSRLKI-----FAGRGAREYKFPGFVGCMLNLRI-DSHKITARHLSKQK 367

Query: 1507 VRDG-----CQSRADCMLSICPPYSKCVTSWDSSTCTC 1539
              +G     C +   C  + C     C   W S  C C
Sbjct: 368  YSNGIDATKCATSNRCFPNPCINRGTCWQDWQSFYCDC 405



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 12/35 (34%), Positives = 19/35 (54%)

Query: 1180 GGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDD 1214
            G K+E+ +  N+ DG WH+V        + + LDD
Sbjct: 272  GSKAELRMGENLNDGEWHSVNASIVPPNVQLTLDD 306


>SB_32196| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1333

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P+F +K Y   + ED +V D+  I  + A D        IRY+I   +     +ID  +G
Sbjct: 141 PEFEQKEYEAEIREDAAVGDD--ILTVTALDRCSKHPDKIRYSIAEESDDELLTIDENNG 198

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236
            + + K+L+    +S  L ++A  G   S
Sbjct: 199 RIKVAKSLESSAGKSLELTVQANKGADQS 227



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATD--ADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F   +YE E+ ED   G  ++T+TA D  +   +++ Y I   +     +I   NGR  I
Sbjct: 143 FEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSIAEESDDELLTIDENNGR--I 200

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
            VA+ L+    +   LTV A + G     A   + +T
Sbjct: 201 KVAKSLESSAGKSLELTVQA-NKGADQSVAKAHVRVT 236



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 7/96 (7%)

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P FE   Y A + EDA +G  +L V+A D       +I YS++ E         D+   I
Sbjct: 141 PEFEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSIAEE-------SDDELLTI 193

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           +   G I   K L+        LTV A  G   S++
Sbjct: 194 DENNGRIKVAKSLESSAGKSLELTVQANKGADQSVA 229



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           P F+Q+ Y A I EDA VG  +  V A D       +I Y +  ++ ++    ID  +G 
Sbjct: 141 PEFEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSI-AEESDDELLTIDENNGR 199

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           I+  K+L+  +  + +L   A  G      S    H+++
Sbjct: 200 IKVAKSLESSAGKSLELTVQANKGA---DQSVAKAHVRV 235



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 18/50 (36%), Positives = 29/50 (58%)

Query: 21  PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           P FE ++YEA +RE A+ G  +LT+ A D+      ++ Y+I   + D L
Sbjct: 141 PEFEQKEYEAEIREDAAVGDDILTVTALDRCSKHPDKIRYSIAEESDDEL 190


>SB_44376| Best HMM Match : EGF_CA (HMM E-Value=7.8e-22)
          Length = 84

 Score = 41.9 bits (94), Expect = 0.007
 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 6/66 (9%)

Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRV--GPQCVSACELGPCGAARC----VPDQTPKGYSC 1573
            S C P +KC+    S  C C  G +  G  C    E    G A C        TP  + C
Sbjct: 10   SPCDPNAKCINMMGSYACGCNEGFLGDGTNCTDVDECSTPGVATCSNLATCINTPGSFKC 69

Query: 1574 ACEPGY 1579
             C+PGY
Sbjct: 70   ECKPGY 75


>SB_34553| Best HMM Match : F5_F8_type_C (HMM E-Value=8.3e-22)
          Length = 667

 Score = 41.9 bits (94), Expect = 0.007
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 8/68 (11%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            T +TC CP  +TG  CET +         D S C++G  C  + +       C+  +AYT
Sbjct: 236  TGYTCTCPSEYTGTECETQVQPC------DSSPCKNGGACANKADNS--GYTCACASAYT 287

Query: 1100 TAVCELRA 1107
               CE +A
Sbjct: 288  GIECESQA 295



 Score = 39.9 bits (89), Expect = 0.029
 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 4/49 (8%)

Query: 1536 TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
            TCTC +   G +C   V  C+  PC     C       GY+CAC   YT
Sbjct: 239  TCTCPSEYTGTECETQVQPCDSSPCKNGGACANKADNSGYTCACASAYT 287



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDCADSTGP 1354
            C  +   C S+PC NG  C++  D   Y C C   +TG +C     P
Sbjct: 251  CETQVQPCDSSPCKNGGACANKADNSGYTCACASAYTGIECESQAHP 297


>SB_33149| Best HMM Match : DSL (HMM E-Value=5.60519e-45)
          Length = 443

 Score = 41.9 bits (94), Expect = 0.007
 Identities = 31/119 (26%), Positives = 46/119 (38%), Gaps = 8/119 (6%)

Query: 1570 GYSCACEPGYTLTTS-GCIES-GKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCH 1627
            G  C C P    +    C E+ G++ C  GW+G +    C+       H +CN + G   
Sbjct: 152  GPECDCRPRLDASAGYTCNETTGQKICYPGWYGRNCNVACSPRNDSTGHYNCNADTGAKE 211

Query: 1628 CKENHYKPEGTAECLP----CQCYAAGSENSSCEAATGQCH--CRPGVIGRACDACANA 1680
            C E+    +    C+P      C A G+          QCH  C+P  I   C +   A
Sbjct: 212  CLESWIGEQCDVYCVPDNQTHSCLANGTRKCQQHWYGQQCHVFCQPRPIQYTCQSTTGA 270



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 10/108 (9%)

Query: 1586 CIESGKEECPGGWWGGSACGPCAC---DVTRGYHPHCNKENGKCHCKENHYKPEGTAECL 1642
            C  +G   C  GW+    C        D T  Y   C+ + G   C      PE   +C 
Sbjct: 103  CDVTGSRVCLPGWYPREQCETLCIPHNDSTASYT--CDSQTGSKTCLSGWSGPE--CDCR 158

Query: 1643 PCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGC 1690
            P    +AG    +C   TGQ  C PG  GR C+   +   + T +  C
Sbjct: 159  PRLDASAGY---TCNETTGQKICYPGWYGRNCNVACSPRNDSTGHYNC 203



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 36/155 (23%), Positives = 51/155 (32%), Gaps = 14/155 (9%)

Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTS-GC 1586
            C++ W    C C   R+       C     G   C P    +  + AC P    T    C
Sbjct: 146  CLSGWSGPECDCRP-RLDASAGYTCN-ETTGQKICYPGWYGRNCNVACSPRNDSTGHYNC 203

Query: 1587 -IESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ 1645
              ++G +EC   W G      C  D       H    NG   C+++ Y  +    C P  
Sbjct: 204  NADTGAKECLESWIGEQCDVYCVPD----NQTHSCLANGTRKCQQHWYGQQCHVFCQPRP 259

Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
                     +C++ TG   C  G  G  C     A
Sbjct: 260  I------QYTCQSTTGAKVCSQGWYGEDCSTFCKA 288



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 12/109 (11%)

Query: 1628 CKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDA-CANAYAEVTP 1686
            C  ++Y P  T  C+P       S + +C+  TG   CRPG  G  C   C +   +V+ 
Sbjct: 9    CTRDYYGPNCTTHCIPRD---GTSGHYTCDLKTGGRVCRPGWHGPQCRVYCISRDDDVSG 65

Query: 1687 NSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDET 1735
            +  C+    G         W     +GV   T C P ++  A   CD T
Sbjct: 66   HFTCQT---GTGLKICLANW-----YGVLCKTYCAPINNSDAGYNCDVT 106



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 12/112 (10%)

Query: 1575 CEP--GYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENH 1632
            C+P    TL    C + G   C   W+G      C        H  C   +G+  C E+ 
Sbjct: 320  CKPHRNSTLGYYRCDDHGNPVCERDWYGTKCTVYCRPRDDEEGHYSCGAVDGRRVCLEDW 379

Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEAATGQCH--CR---PGVIGRACDACAN 1679
            Y    T  C+     A    + +C+  TGQ H  CR    GV+G    + A+
Sbjct: 380  YGENCTVHCV-----ADKEGHFTCDGKTGQRHRLCRLLAAGVLGDGLGSLAH 426


>SB_50993| Best HMM Match : EGF (HMM E-Value=3.4e-19)
          Length = 220

 Score = 41.5 bits (93), Expect = 0.009
 Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            C+ APC N   C++L D   Y C CK+G TGK+C
Sbjct: 120  CAEAPCQNEGLCANLPDYSDYTCTCKKGFTGKNC 153



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 8/85 (9%)

Query: 1513 SRADCMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQ 1566
            ++  C  + C     C    D S  TCTC+ G  G  C   ++AC+  PC     C    
Sbjct: 116  AKEPCAEAPCQNEGLCANLPDYSDYTCTCKKGFTGKNCEKEMTACDSQPCANGGACKATA 175

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGK 1591
               GY CAC  G+      C   GK
Sbjct: 176  EQPGYICACLSGF--EGDACQNKGK 198



 Score = 37.9 bits (84), Expect = 0.12
 Identities = 13/39 (33%), Positives = 23/39 (58%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQ 1078
            + +TC C +GFTG NCE  +T    +   +G  C++ ++
Sbjct: 138  SDYTCTCKKGFTGKNCEKEMTACDSQPCANGGACKATAE 176



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 2/41 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDT--YICDCKEGHTGKDC 1348
            C ++ + C S PC NG  C    +   YIC C  G  G  C
Sbjct: 153  CEKEMTACDSQPCANGGACKATAEQPGYICACLSGFEGDAC 193


>SB_47717| Best HMM Match : EGF (HMM E-Value=1.9e-29)
          Length = 214

 Score = 41.5 bits (93), Expect = 0.009
 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  + C     C+   +  TC C+ G +G +C   ++ C   PC   A+C   Q   G+
Sbjct: 10   ECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRCHAVINKCLFNPCKNGAKCQTLQ-DGGH 68

Query: 1572 SCACEPGY--TLTTSGCIESGKEECPGGWWGGSACG----PCACDVTRGY-HPHCNKENG 1624
             C CE G+  +L      E  + + P    G    G     CAC++  GY    CN    
Sbjct: 69   RCLCEKGFKGSLCEVNVNECNETQSPCSEHGACIDGVNSYTCACNL--GYTGSTCNVTVN 126

Query: 1625 KC 1626
             C
Sbjct: 127  DC 128



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAY 1098
            +  FTC+C +GF G  C  ++ K  C  +     C++G++C   ++GG     C  +  +
Sbjct: 26   INGFTCKCQDGFIGDRCHAVINK--CLFNP----CKNGAKCQTLQDGG---HRCLCEKGF 76

Query: 1099 TTAVCEL 1105
              ++CE+
Sbjct: 77   KGSLCEV 83



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 14/41 (34%), Positives = 18/41 (43%)

Query: 1308 AGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            A C      C S PCY    C D  + + C C++G  G  C
Sbjct: 2    ATCDIDIDECQSNPCYFNGTCIDGINGFTCKCQDGFIGDRC 42



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348
            C    ++C   PC NGA+C  L D  + C C++G  G  C
Sbjct: 42   CHAVINKCLFNPCKNGAKCQTLQDGGHRCLCEKGFKGSLC 81


>SB_52863| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 575

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 37/134 (27%), Positives = 49/134 (36%), Gaps = 17/134 (12%)

Query: 1509 DGCQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQ 1566
            D C    +C L +  C   S CV ++ +  C C  G  G    +AC    C  A CV   
Sbjct: 31   DKCPDVNECRLGLDSCHYNSTCVNTYGTYHCICNPGYTG-DGKTACN-KTCYPA-CVHGT 87

Query: 1567 TPKGYSCAC-----EPGYTLTTSGCIESGKEECPGGWWGGSACGPCAC----DVTRGYHP 1617
                Y C C     EP   L       +   +          C  C C    DVT G   
Sbjct: 88   CNSNYLCDCDLGCLEPTVRLIVGVTDTAHVTKASASVTSAKGCKACDCNGHGDVTLGV-- 145

Query: 1618 HCNKENGKCHCKEN 1631
             C++  G+C CK+N
Sbjct: 146  -CDRMTGQCFCKDN 158



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 43/165 (26%), Positives = 56/165 (33%), Gaps = 14/165 (8%)

Query: 1549 VSACELG--PCGA-ARCVPDQTPKGYSCACEPGYTLT-TSGCIESGKEECPGGWWGGSAC 1604
            V+ C LG   C   + CV   T   Y C C PGYT    + C ++    C  G    +  
Sbjct: 36   VNECRLGLDSCHYNSTCV--NTYGTYHCICNPGYTGDGKTACNKTCYPACVHGTCNSNYL 93

Query: 1605 GPCACDVTRGYHPHCNKENG---KCHCKENHYKPEGTAECLPCQCYAAGSENSS-CEAAT 1660
              C CD+     P      G     H  +          C  C C   G      C+  T
Sbjct: 94   --CDCDLGC-LEPTVRLIVGVTDTAHVTKASASVTSAKGCKACDCNGHGDVTLGVCDRMT 150

Query: 1661 GQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGV 1705
            GQC C+    G  C+ C +      P  G    Y+   RS    V
Sbjct: 151  GQCFCKDNTEGLNCERCKSGLVG-NPRYGGRCYYECKSRSILTNV 194



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)

Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC 1674
            C C  +   P+ T    P  C    S + SC +A+G C C PG  G  C
Sbjct: 348  CRCASDWTGPDCTIRVCPNNC----SGHGSCNSASGLCTCAPGYAGTDC 392



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 18/62 (29%), Positives = 23/62 (37%), Gaps = 5/62 (8%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGPQC-VSACELGPCGAARCVPDQTPKGYSCACEPGYT 1580
            C    +CV +     C C +   GP C +  C     G   C    +  G  C C PGY 
Sbjct: 333  CHGNRRCVMTSQGEACRCASDWTGPDCTIRVCPNNCSGHGSC---NSASGL-CTCAPGYA 388

Query: 1581 LT 1582
             T
Sbjct: 389  GT 390


>SB_47423| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 855

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 12/91 (13%)

Query: 1129 LKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITV- 1187
            +  +FAT    G+++++  ++   D + +EL      +G    +R SF LG G+  IT  
Sbjct: 299  IAFRFATGNPDGVIVHSSMFD---DHVVVEL-----SKGF---VRVSFDLGQGRLNITSR 347

Query: 1188 EGNVGDGSWHTVEIEYFNRTITMILDDCDKV 1218
            EG + DG+WH+V I    R +T+ LD   +V
Sbjct: 348  EGCLHDGTWHSVTIHRKRRRVTLDLDKQKRV 378



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 6/77 (7%)

Query: 1271 PSSF-QVKNKDFVGCISDFYIDHKFIDLNSYV-ADNGTLAGCPEKRSRCSSAPCYNGAEC 1328
            P++F Q     FVGC       +   +    +   NGT  GC    + C+   C NG +C
Sbjct: 663  PTAFWQSMQHGFVGCTRGMKYGYLGKESRPKINRTNGTRVGCG---NACAVLKCRNGGKC 719

Query: 1329 SDLWDTYICDCK-EGHT 1344
             +      CDC+  GHT
Sbjct: 720  VNRIIVAECDCRGTGHT 736


>SB_47176| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 471

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 34/187 (18%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574
            C   +KC  +  S  C C  G  G   +C  +  C  G   C   ARC  + T   Y C 
Sbjct: 71   CDKNAKCNNTIGSYHCMCNPGFSGDGRECTDIDECVTGDHTCDKNARC--NNTIGSYHCT 128

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634
            C PG++     C +   +EC        A G   CD     +  CN   G  HC+ N   
Sbjct: 129  CNPGFSGDGRNCTDI--DEC--------ATGDHTCD----KNAKCNNTIGSYHCRCNPGF 174

Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC---DACANAYAE 1683
                  C        G     +N+ C    G   C C PG    GR C   D C      
Sbjct: 175  SGDGRNCTDIDECVTGDHTCDKNARCNNIIGSYHCTCNPGFSGDGRNCTDIDECVTGDHT 234

Query: 1684 VTPNSGC 1690
               N+ C
Sbjct: 235  CDKNAKC 241



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 52/188 (27%), Positives = 67/188 (35%), Gaps = 36/188 (19%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELG--PCGA-ARCVPDQTPKGYSCA 1574
            C   +KC  +  S  CTC  G  G   +C  +  C  G   C   A+C  +     Y C 
Sbjct: 235  CDKNAKCNNTIGSYHCTCNPGFSGDGRECTDIDECVTGDHTCDKNAKC--NNIIGSYHCM 292

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDVTRG-YHPHCN---KENGKCHCK 1629
            C PG++     C +   +EC     G   C   A C  T G YH  CN     NG+  C 
Sbjct: 293  CNPGFSGNGRECTDI--DECV---TGDHTCDKNARCGNTIGSYHCTCNPGFSGNGR-ECT 346

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVI--GRAC---DACANAYA 1682
            +      G   C          +N+ C    G   C C PG    GR C   D C     
Sbjct: 347  DTDECVTGDHTC---------DKNARCGNTIGSYHCTCNPGFSGNGRECTDIDECVTGDY 397

Query: 1683 EVTPNSGC 1690
                N+ C
Sbjct: 398  TCDKNAKC 405


>SB_41795| Best HMM Match : EGF (HMM E-Value=8.7e-11)
          Length = 83

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 15/36 (41%), Positives = 20/36 (55%)

Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            + S CS  PC NG  C++    Y C C EG +G +C
Sbjct: 43   RTSNCSPNPCQNGGVCTETATGYTCQCLEGFSGVNC 78



 Score = 36.7 bits (81), Expect = 0.27
 Identities = 13/17 (76%), Positives = 15/17 (88%)

Query: 1040 TSFTCQCPEGFTGVNCE 1056
            T +TCQC EGF+GVNCE
Sbjct: 63   TGYTCQCLEGFSGVNCE 79


>SB_32588| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1135

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 14/91 (15%)

Query: 1129 LKLKFATQTTSGLLLYNGRYNERH-DFLALELVSSEAGRGGGPGLRFSFSLGGGKS---- 1183
            ++L+F T   +GLLL+     E + D+  +EL+        G  LRF+ SLG  +     
Sbjct: 51   IELQFRTIQPNGLLLHGSSSGEEYGDYFTIELI--------GGKLRFAISLGRRQGIDDM 102

Query: 1184 -EITVEGNVGDGSWHTVEIEYFNRTITMILD 1213
              +T+   + D  +HTV IE+ NR + + LD
Sbjct: 103  VNMTLGDGLADNKFHTVLIEHNNREVWLFLD 133



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTL-AGCPEKR 1314
            LD+ G L IGG        ++ N  FVGCI  F I+ + ++L     D   +  GC    
Sbjct: 759  LDVVGNLFIGGYMR-----EMMN-GFVGCIRGFTINGEVLNLARLSKDFDYVNEGC---Y 809

Query: 1315 SRCSS-APCYNGAECSDLWDTYICDC 1339
            S C++   C  GA C+D ++ Y CDC
Sbjct: 810  SACNNETQCKGGARCTDDYNIYKCDC 835



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 1416 ATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLL 1475
            A L+ G WH +E + +G  I+V ++      + P  A+  Q  +IG + IGG        
Sbjct: 293  APLNTGMWHHVEFE-IGP-IAVWINVDKMVDMRPPSADLPQNFFIGSVQIGG-------- 342

Query: 1476 ASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDG-CQSRADCMLSICPPYSKCVTSWDS 1534
                  F GC+ ++ +   +      +  E +  G C     C  ++C   SKC+    +
Sbjct: 343  -----DFVGCVLNIELNGVKFDPKSLSPTEYIEVGTCHITDFCFPTVCQHGSKCIQDGKT 397

Query: 1535 STCTC 1539
              C C
Sbjct: 398  FGCDC 402



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 17/64 (26%), Positives = 25/64 (39%)

Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339
            DFVGC+ +  ++    D  S         G       C    C +G++C     T+ CDC
Sbjct: 343  DFVGCVLNIELNGVKFDPKSLSPTEYIEVGTCHITDFCFPTVCQHGSKCIQDGKTFGCDC 402

Query: 1340 KEGH 1343
               H
Sbjct: 403  LNTH 406


>SB_14770| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 41

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 18/41 (43%), Positives = 26/41 (63%)

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           +A DGG PP +ST  V I++ D ND+PPV +   +   +SE
Sbjct: 1   MAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 41



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 18/40 (45%), Positives = 24/40 (60%)

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           A+DGG P L+ TT V I V D NDN PV +  +   ++ E
Sbjct: 2   AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 41



 Score = 39.1 bits (87), Expect = 0.050
 Identities = 17/40 (42%), Positives = 25/40 (62%)

Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           AQDGG P  ++TT + I + D NDN P    ++ + S+SE
Sbjct: 2   AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 41


>SB_7289| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 278

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 48/183 (26%), Positives = 64/183 (34%), Gaps = 30/183 (16%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELG--PCGA-ARCVPDQTPKGYSCA 1574
            C   +KC  +  S  CTC  G    G  C  +  C  G   C   A+C  + T   Y C 
Sbjct: 102  CDKNAKCNNTIGSYHCTCNPGFSGGGRNCTDIDECVTGDHTCDKNAKC--NNTIGSYHCM 159

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634
            C PG++     C +   +EC          G   CD     +  CN   G  HC  N   
Sbjct: 160  CNPGFSGDGRECTDI--DEC--------VTGDHTCD----KNARCNNTIGSYHCMCNPGF 205

Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVIGRACDACANAYAEVTPNS 1688
                 EC        G     +N+ C    G   C C PG  G   + C +    VT + 
Sbjct: 206  SGNGRECTDIDECVTGDHTCDKNARCNNTIGSYHCMCNPGFSGNGRE-CTDIDECVTGDH 264

Query: 1689 GCE 1691
             C+
Sbjct: 265  TCD 267



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 38/142 (26%), Positives = 47/142 (33%), Gaps = 27/142 (19%)

Query: 1560 ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC 1619
            ARC  + T   Y C C PG++     C +   +EC          G   CD     +  C
Sbjct: 24   ARC--NNTIGSYHCTCNPGFSGDGINCTDI--DEC--------VTGDHTCD----KNAKC 67

Query: 1620 NKENGKCHCKENHYKPEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--G 1671
            N   G  HC  N        EC        G     +N+ C    G   C C PG    G
Sbjct: 68   NNTIGLYHCMCNPGFSGDGRECTDIDECVTGDHTCDKNAKCNNTIGSYHCTCNPGFSGGG 127

Query: 1672 RAC---DACANAYAEVTPNSGC 1690
            R C   D C         N+ C
Sbjct: 128  RNCTDIDECVTGDHTCDKNAKC 149


>SB_4732| Best HMM Match : EGF (HMM E-Value=2.4e-10)
          Length = 57

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 14/32 (43%), Positives = 21/32 (65%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S+PC N A+C D  ++Y C+C  G  G +C
Sbjct: 5    CASSPCNNNAKCIDTKESYRCECLPGFQGANC 36



 Score = 39.5 bits (88), Expect = 0.038
 Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 4/52 (7%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCV 1563
            DC  S C   +KC+ + +S  C C  G  G  C   V  C+  PC GAA CV
Sbjct: 4    DCASSPCNNNAKCIDTKESYRCECLPGFQGANCDKEVDECDKQPCFGAATCV 55


>SB_57080| Best HMM Match : EGF_CA (HMM E-Value=1.4013e-43)
          Length = 360

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 2/41 (4%)

Query: 1314 RSRCSSAPCYNGAECSDLWD--TYICDCKEGHTGKDCADST 1352
            +S C S PC +GA C   +    YIC C  G+TGK C   T
Sbjct: 107  KSDCISRPCQHGATCLAQYPCTAYICSCTPGYTGKHCETDT 147



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 35/121 (28%), Positives = 47/121 (38%), Gaps = 10/121 (8%)

Query: 1550 SACELGPCG-AARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA 1608
            S C   PC   A C+       Y C+C PGY  T   C E+   EC  G    S    C 
Sbjct: 108  SDCISRPCQHGATCLAQYPCTAYICSCTPGY--TGKHC-ETDTNECADGSHTCSINAACT 164

Query: 1609 CDVTRGYHPHCNK-ENGKCH-CKENHYKPEGTAEC-LPCQC-YAAGSENSSCEAA-TGQC 1663
             +    +   CN    G  H C++ +   +G+  C +   C    GS   +C A  TG  
Sbjct: 165  -NTVGSFTCACNAGYTGNGHTCQDTNECADGSHTCSINAACTNTVGSFTCACNAGYTGNG 223

Query: 1664 H 1664
            H
Sbjct: 224  H 224



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 11/21 (52%), Positives = 15/21 (71%)

Query: 1037 YPVTSFTCQCPEGFTGVNCET 1057
            YP T++ C C  G+TG +CET
Sbjct: 125  YPCTAYICSCTPGYTGKHCET 145



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 11/83 (13%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP----QCVSACELG--PCGA-ARCVPDQTPKGYSCA 1574
            C   + C  +  S TC C AG  G     Q  + C  G   C   A C    T   ++CA
Sbjct: 157  CSINAACTNTVGSFTCACNAGYTGNGHTCQDTNECADGSHTCSINAACT--NTVGSFTCA 214

Query: 1575 CEPGYTLTTSGCIESGKEECPGG 1597
            C  GYT     C ++   EC  G
Sbjct: 215  CNAGYTGNGHTCQDT--NECADG 235



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 11/79 (13%)

Query: 1511 CQSRADCM--LSICPPYSKCVTSWDSSTCTCEAGRVGP----QCVSACELGP--CGA-AR 1561
            CQ   +C      C   + C  +  S TC C AG  G     Q  + C  G   C   A 
Sbjct: 185  CQDTNECADGSHTCSINAACTNTVGSFTCACNAGYTGNGHTCQDTNECADGSHTCSINAA 244

Query: 1562 CVPDQTPKGYSCACEPGYT 1580
            C    T   ++CAC  GYT
Sbjct: 245  CT--NTVGSFTCACNAGYT 261


>SB_41915| Best HMM Match : F5_F8_type_C (HMM E-Value=9.1e-13)
          Length = 317

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 3/59 (5%)

Query: 1300 YVADNGTLAGCPEKRSRCSSA-PCYNGAECSD--LWDTYICDCKEGHTGKDCADSTGPP 1355
            Y AD+  L         CS   PC N A C +  +   Y C C+EG+TG+ C D   PP
Sbjct: 110  YTADSVYLEHLSRPAGSCSGGWPCSNKATCVNVPMMPGYKCYCQEGYTGELCQDCKSPP 168


>SB_15410| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1147

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 55/220 (25%), Positives = 79/220 (35%), Gaps = 35/220 (15%)

Query: 1492 GTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV----GPQ 1547
            G  Q + NR          C    +C++        C  +  S  C C AG      G  
Sbjct: 234  GGYQCICNRGFESTADMKDCVDINECLVDNGRCSEMCNNTLGSYLCDCGAGFALQPDGRT 293

Query: 1548 C--VSACELGP--CGAARCVPDQTPKGYSCACEPGY--TLTTSGCIESGKEECPGGWWGG 1601
            C  +  C   P  CG      +    GY C C  GY  ++ +  CI+   +EC       
Sbjct: 294  CRDIDECMERPDVCGPGNTC-NNIEGGYYCTCGKGYKQSVDSRSCIDV--DECQED---P 347

Query: 1602 SACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP---CQC-YAAGSENSSCE 1657
              C    C  T G        + +C C + +   +GT  C+    CQ   A   EN+ C 
Sbjct: 348  RLCTNGVCRNTPG--------SFECLCAKGYAIAKGTTACVDVNECQTGQAMCHENARCA 399

Query: 1658 AATG--QCHCRPGVI--GRAC---DACANAYAEVTPNSGC 1690
               G  +C C+PG I  G +C   D C    A+ +    C
Sbjct: 400  NLVGSYRCECKPGFIGDGSSCTDVDECTTGIAQCSEQGTC 439



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 54/227 (23%), Positives = 72/227 (31%), Gaps = 39/227 (17%)

Query: 1492 GTAQSLLNRPTVRENVRDGCQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAG-RVGPQ- 1547
            GT + + N+       R  C+   +C +S  +C     C  +  +  C C  G R  P  
Sbjct: 110  GTFECICNQGYGLTADRMDCEDIDECSISAGLCGN-GTCTNTPGAFRCDCNPGFRNAPMM 168

Query: 1548 ---CVSA--CELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGS 1602
               C+    C+  PC    C    T   Y C C  G  L   G     K EC       S
Sbjct: 169  MEICIDIDECDHNPCADGTCY--NTMGSYKCVCPDGMELMKDGVSCEDKNEC-------S 219

Query: 1603 ACGPCACDVTRGYHPHCNKENG--KCHCKENHYKPEGTAECLPC-QCYA-AGSENSSCEA 1658
              G C        H  C   NG  +C C           +C+   +C    G  +  C  
Sbjct: 220  DPGVCV-------HGRCENFNGGYQCICNRGFESTADMKDCVDINECLVDNGRCSEMCNN 272

Query: 1659 ATGQ--CHCRPGVI----GRAC---DACANAYAEVTPNSGCEVVYDG 1696
              G   C C  G      GR C   D C        P + C  +  G
Sbjct: 273  TLGSYLCDCGAGFALQPDGRTCRDIDECMERPDVCGPGNTCNNIEGG 319



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 2/53 (3%)

Query: 1300 YVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGH--TGKDCAD 1350
            Y    GT A       +   A C+  A C++L  +Y C+CK G    G  C D
Sbjct: 370  YAIAKGTTACVDVNECQTGQAMCHENARCANLVGSYRCECKPGFIGDGSSCTD 422



 Score = 34.3 bits (75), Expect = 1.4
 Identities = 41/154 (26%), Positives = 55/154 (35%), Gaps = 17/154 (11%)

Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCI 1587
            CV +  S  C C AG       +AC        RC    T  G    CE  + L   G  
Sbjct: 11   CVNTPGSYRCECSAGLTLDSIQNACV--DLRKDRCYMTITESG----CEKPFGL---GLY 61

Query: 1588 ESGKEECPGGWWGGSACG-PCA-CDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQ 1645
            +  K++C     G +  G PC  C +       CN   G C         +GT EC+  Q
Sbjct: 62   K--KDDCCCSAVGAAGWGTPCQECPLQNTDINECNTWQGLCR-NGRCVNKQGTFECICNQ 118

Query: 1646 CYAAGSENSSCEAATGQCHCRPGVIGRACDACAN 1679
             Y   ++   CE    +C    G+ G     C N
Sbjct: 119  GYGLTADRMDCE-DIDECSISAGLCGNG--TCTN 149



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 7/74 (9%)

Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC--GAARCVPD----QTPKGYSC 1573
            ++C   ++C     S  C C+ G +G    S  ++  C  G A+C        TP  + C
Sbjct: 390  AMCHENARCANLVGSYRCECKPGFIGDGS-SCTDVDECTTGIAQCSEQGTCVNTPGSHRC 448

Query: 1574 ACEPGYTLTTSGCI 1587
             C  GYT     C+
Sbjct: 449  VCHEGYTGDGITCV 462


>SB_48923| Best HMM Match : EGF_CA (HMM E-Value=3.2e-27)
          Length = 83

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 29/80 (36%), Positives = 38/80 (47%), Gaps = 11/80 (13%)

Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELG--PCGA-ARCVPDQ 1566
            +C L+I  CP    CV +  S TC C+ G   V   C  +  C LG   C A A CV   
Sbjct: 4    ECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCV--N 61

Query: 1567 TPKGYSCACEPGYTLTTSGC 1586
                Y+C C+ G+TL  + C
Sbjct: 62   NDGSYTCRCKRGFTLVNNTC 81


>SB_41903| Best HMM Match : HRM (HMM E-Value=0.00061)
          Length = 139

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 27/100 (27%), Positives = 39/100 (39%), Gaps = 11/100 (11%)

Query: 1663 CHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPP 1722
            C C PG +G       N +     + G     D C       + W RT  G   +T CP 
Sbjct: 48   CKCGPGFVG-------NGFLCRVESPGLSDK-DFCGPITTQNIKWSRTLKGQTDVTSCPK 99

Query: 1723 GSSGRATRTCDE---TKDVPWQDPDMFNCTTATFYQLRKQ 1759
              +G A R C E    +D  W  PD+  C +     +++Q
Sbjct: 100  DVTGVARRKCKEQEPDQDASWDTPDLSECISEWALNIKEQ 139


>SB_39963| Best HMM Match : EGF (HMM E-Value=1.4e-13)
          Length = 3035

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 14/35 (40%), Positives = 22/35 (62%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            C+  PC NG +C +  D Y+C C  G+TG +C ++
Sbjct: 160  CALFPCKNGGQCVNKDDGYLCLCPPGNTGDECQET 194



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 10/78 (12%)

Query: 1507 VRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARC 1562
            +++ CQ+   C    C P    V   D   C C+    G  C   +  C L PC    +C
Sbjct: 116  IKNKCQTPGLCKNGTCYP----VYETDDFRCECKLNFSGRHCEIAIKDCALFPCKNGGQC 171

Query: 1563 VPDQTPKGYSCACEPGYT 1580
            V      GY C C PG T
Sbjct: 172  V--NKDDGYLCLCPPGNT 187



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 7/55 (12%)

Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILC 1089
            P+Y    F C+C   F+G +CE  +    C +      C++G QCV  ++ G LC
Sbjct: 133  PVYETDDFRCECKLNFSGRHCEIAI--KDCAL----FPCKNGGQCV-NKDDGYLC 180


>SB_39510| Best HMM Match : VWA (HMM E-Value=0)
          Length = 705

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 14/46 (30%), Positives = 23/46 (50%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355
            C      C + PC +G  C++   +Y C+C  G+ GK+C  +   P
Sbjct: 74   CETGIDECLNLPCKHGGTCNNKGGSYSCECSTGYVGKNCKQNFTDP 119



 Score = 40.3 bits (90), Expect = 0.022
 Identities = 12/34 (35%), Positives = 20/34 (58%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            +C++ PC N   C+ ++  + C C  G  GKDC+
Sbjct: 4    KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 37



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 6/67 (8%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYS 1572
            C  S C     C+ S+ S TC C+ G  G  C   +  C   PC     C  +     YS
Sbjct: 43   CKSSPCNKNQNCINSFGSFTCVCKDGFKGDNCETGIDECLNLPCKHGGTC--NNKGGSYS 100

Query: 1573 CACEPGY 1579
            C C  GY
Sbjct: 101  CECSTGY 107



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 12/39 (30%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C     +C S+PC     C + + ++ C CK+G  G +C
Sbjct: 36   CSLDVDKCKSSPCNKNQNCINSFGSFTCVCKDGFKGDNC 74



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 12/17 (70%), Positives = 13/17 (76%)

Query: 1041 SFTCQCPEGFTGVNCET 1057
            SFTC C +GF G NCET
Sbjct: 60   SFTCVCKDGFKGDNCET 76



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 3/49 (6%)

Query: 1317 CSSAPCYNGAECSDLW-DTYICDCKEGHTGKDC--ADSTGPPWRFGGDG 1362
            C+  PC NG  C       Y C C  G TG +C  A  +G    F  DG
Sbjct: 302  CTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETACKSGIDLVFAVDG 350



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 1/40 (2%)

Query: 1517 CMLSICPPYSKCVTSWDSS-TCTCEAGRVGPQCVSACELG 1555
            C  + C     C+ S  S  TCTC  G  G  C +AC+ G
Sbjct: 302  CTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETACKSG 341


>SB_33920| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1278

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 47/163 (28%), Positives = 65/163 (39%), Gaps = 25/163 (15%)

Query: 1573 CACEPGYTLTTSGCIESGKEECPGGWWGGSACGPC-------ACDVTRGYHPHC--NKEN 1623
            CAC PGY+  +    E G      G + G  C PC       +CD   G   +C  N   
Sbjct: 511  CACPPGYSGLSCETCEPGYYRKHEGKFLGK-CLPCNCNRHAKSCDANTGKCNNCLHNTIG 569

Query: 1624 GKC-HCKENHY--KPEGTA-ECLPCQCYAAGSEN---SSC---EAATGQC-HCRPGVIGR 1672
              C  CK+ +Y     GT  +C PC C      N   S+C   +     C +C+ G  GR
Sbjct: 570  KNCEQCKKGYYGDPTVGTEDDCRPCACPMTKPPNKFSSTCFLDKDGKQTCDNCQLGYKGR 629

Query: 1673 ACDACANAYA--EVTPNSGCEVVYD-GC-PRSFAGGVWWPRTK 1711
             C++C   +    +     C+   D GC PR  A     P T+
Sbjct: 630  NCESCLTPFVGNPLVIGDYCKFEEDCGCDPRGSANSSCNPFTR 672


>SB_12645| Best HMM Match : Laminin_EGF (HMM E-Value=3e-31)
          Length = 541

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 13/90 (14%)

Query: 1596 GGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSE--- 1652
            G + GG  C  C  + T G +  C +      CK+ +++P G  +  P  C A   +   
Sbjct: 440  GRYEGGGVCEDCQHN-TAGIN--CER------CKQGYFRPRGVDKTSPFACRACNCDPQY 490

Query: 1653 -NSSCEAATGQCHCRPGVIGRACDACANAY 1681
                C    G C C+P   G  CD C   +
Sbjct: 491  TTGRCYDENGDCECKPRYGGPRCDRCREGF 520


>SB_6849| Best HMM Match : EGF_2 (HMM E-Value=9.3e-11)
          Length = 439

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 41/166 (24%), Positives = 61/166 (36%), Gaps = 20/166 (12%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKG 1570
            C+  ++C  S+   + +C T+ D   C CE    G  C     +G C     V      G
Sbjct: 4    CEFISNC--SVPCSHGRCTTAPDK--CECEKYWSGADC--GTYIGTCNNCSSVGGTCSAG 57

Query: 1571 Y-SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCK 1629
              +CAC PGYT  T  C     ++C G       CG  +C ++ G    C  + G  +  
Sbjct: 58   PDTCACRPGYTGPT--C---AVQKCDG-------CGHGSCQISAG-KKSCTCDYGWLNNV 104

Query: 1630 ENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACD 1675
             +     G   C             +C +   +C CR    G  CD
Sbjct: 105  GDASFTPGRGPCTKIWKCTEPCVYGTCPSDPFKCECRAPYTGTQCD 150



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 19/75 (25%), Positives = 27/75 (36%), Gaps = 7/75 (9%)

Query: 1616 HPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIG---- 1671
            H  C     KC C++  Y            C    S   +C A    C CRPG  G    
Sbjct: 16   HGRCTTAPDKCECEK--YWSGADCGTYIGTCNNCSSVGGTCSAGPDTCACRPGYTGPTCA 73

Query: 1672 -RACDACANAYAEVT 1685
             + CD C +   +++
Sbjct: 74   VQKCDGCGHGSCQIS 88


>SB_58051| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 42

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%)

Query: 1317 CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            C S+PC NG+ C++  D   Y C C  G+TG+ C
Sbjct: 6    CDSSPCSNGSVCNNTQDGKNYTCTCSPGYTGRHC 39



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 13/30 (43%), Positives = 16/30 (53%), Gaps = 1/30 (3%)

Query: 1552 CELGPCG-AARCVPDQTPKGYSCACEPGYT 1580
            C+  PC   + C   Q  K Y+C C PGYT
Sbjct: 6    CDSSPCSNGSVCNNTQDGKNYTCTCSPGYT 35


>SB_26475| Best HMM Match : Cadherin (HMM E-Value=0.009)
          Length = 340

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 10/105 (9%)

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           D+N++P + E    T Y  ENSP GT +G +   DP E P+    +S+  G D   F++ 
Sbjct: 19  DVNEAPTLIELSRNTAY--ENSPAGTYVGTLTCEDP-EMPDDSCTFSVV-GPDGVPFAVR 74

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEI 782
               SD   L+    LD+E+     ++++RA  +  L+ DV + I
Sbjct: 75  ----SDGKSLIVDGPLDHET-NPVLDVIVRATDNGGLYEDVTLTI 114



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 4/84 (4%)

Query: 377 EDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
           E+ P GT V TLT  D +  D+   + + G +    F++ S +G+ LI V  PLD +   
Sbjct: 36  ENSPAGTYVGTLTCEDPEMPDDSCTFSVVGPD-GVPFAVRS-DGKSLI-VDGPLDHETNP 92

Query: 436 RYVLTVSATDSGGRSDTAMVQINI 459
              + V ATD+GG  +   + I +
Sbjct: 93  VLDVIVRATDNGGLYEDVTLTIGL 116


>SB_5780| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 263

 Score = 40.7 bits (91), Expect = 0.016
 Identities = 58/221 (26%), Positives = 76/221 (34%), Gaps = 38/221 (17%)

Query: 1491 IGTAQSLLNRPTVRENVRDGCQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP-- 1546
            IG+     N P    N R+ C    +C+     C   +KC  +  S  CTC  G  G   
Sbjct: 15   IGSYHCTCN-PGFSGNGRE-CTDIDECVTGDHTCDKNAKCNNTIGSYHCTCNPGFSGDGR 72

Query: 1547 QC--VSACELGP--CGA-ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGG 1601
             C  +  C  G   C   A+C  D T   Y C C PG++     C +   +EC       
Sbjct: 73   NCTDIDECVTGDHTCDKNAKC--DNTIGSYHCMCNPGFSGDGRECTDI--DEC------- 121

Query: 1602 SACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPC-QCYAAG---SENSSCE 1657
               G   CD     +  CN   G  HC  N         C    +C        +N+ C 
Sbjct: 122  -VTGDHTCD----KNAKCNNIIGSYHCTCNPGFSGDGRNCTDIDECLTGDHTCDKNAKCN 176

Query: 1658 AATG--QCHCRPGVI--GRAC---DACANAYAEVTPNSGCE 1691
               G   C C PG    GR C   D C         N+ C+
Sbjct: 177  NTIGSYHCTCNPGFSGDGRNCTDIDECVTGDHTCDKNAKCD 217



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 13/96 (13%)

Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-AR 1561
            C    +C+     C   +KC  +  S  CTC  G  G    C  +  C  G   C   A+
Sbjct: 156  CTDIDECLTGDHTCDKNAKCNNTIGSYHCTCNPGFSGDGRNCTDIDECVTGDHTCDKNAK 215

Query: 1562 CVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597
            C  D T   Y C C PG++     C ++  +EC  G
Sbjct: 216  C--DNTIGSYHCTCNPGFSGNGRECTDT--DECVTG 247


>SB_7527| Best HMM Match : DSL (HMM E-Value=2.5e-34)
          Length = 542

 Score = 40.3 bits (90), Expect = 0.022
 Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 20/146 (13%)

Query: 1538 TCEAGRVGPQCVSACELGP---C---GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGK 1591
            TC  G  G +C   C   P   C   G   C+P+   K  S  C P      +    +G+
Sbjct: 304  TCLPGWHGDRCNIYCRKTPTSICDGSGKKYCLPNWYGKDCSKYCAPTGNFACNSL--TGE 361

Query: 1592 EECPGGWWGGSACGPCAC--DVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAA 1649
              C  GW+G      C    D T  +   C+ E G+  C +  Y   GT     C+ +  
Sbjct: 362  RGCVAGWYGDQCDRYCIATHDDTAAFS--CS-ETGEKVCHKGWY---GTN----CERHCV 411

Query: 1650 GSENSSCEAATGQCHCRPGVIGRACD 1675
             + NS C   TG+  C  G  G  CD
Sbjct: 412  RTRNSVCSNITGERICNKGWHGVNCD 437



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 23/125 (18%)

Query: 1589 SGKEECPGGWWGGSACGPCA-----------CDVTRGYH---PHCNKENGKCHCKENHYK 1634
            +G++ C  GW G S   PC            CD T G     P  + +    +C++    
Sbjct: 265  TGRKICLPGWHGVSCRVPCVPHNDNVNGHYTCDATTGSKTCLPGWHGDRCNIYCRKTPTS 324

Query: 1635 ---PEGTAECLP------CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685
                 G   CLP      C  Y A + N +C + TG+  C  G  G  CD    A  + T
Sbjct: 325  ICDGSGKKYCLPNWYGKDCSKYCAPTGNFACNSLTGERGCVAGWYGDQCDRYCIATHDDT 384

Query: 1686 PNSGC 1690
                C
Sbjct: 385  AAFSC 389


>SB_34550| Best HMM Match : VWA (HMM E-Value=0)
          Length = 519

 Score = 40.3 bits (90), Expect = 0.022
 Identities = 12/34 (35%), Positives = 20/34 (58%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            +C++ PC N   C+ ++  + C C  G  GKDC+
Sbjct: 4    KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 37



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC-ADSTGP 1354
            C      C S+PC     C + + ++ C CK+G    +C  D T P
Sbjct: 36   CSLDVDECKSSPCNKNQNCINSFGSFTCVCKDGLKADNCETDFTDP 81


>SB_1891| Best HMM Match : EGF (HMM E-Value=6.5e-15)
          Length = 106

 Score = 40.3 bits (90), Expect = 0.022
 Identities = 12/34 (35%), Positives = 20/34 (58%)

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA 1349
            +C++ PC N   C+ ++  + C C  G  GKDC+
Sbjct: 33   KCATNPCKNSGTCTSVYSDFNCTCSSGFQGKDCS 66



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 11/39 (28%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C S+PC     C + + ++ C CK+G    +C
Sbjct: 65   CSLDVDECKSSPCNKNQNCINSFGSFTCVCKDGFKADNC 103


>SB_53569| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 921

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 47/173 (27%), Positives = 65/173 (37%), Gaps = 31/173 (17%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVG----PQC--VSACEL--GPCGAARC 1562
            C    +CM  I P    C+    S  C C  G V       C  V+ CE+  G CG   C
Sbjct: 476  CMDIDECMEGI-PECFNCINLRGSYRCECGQGFVPNANQTHCSDVNECEVQNGGCGKHTC 534

Query: 1563 VPDQTPKGYSCACEPGYTL--TTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620
            +   T   Y C C  GY L   T  C++   +EC      G       C  T G      
Sbjct: 535  I--NTYGSYKCQCLDGYRLDARTEQCVDI--DECARNHGKGDC--EHLCTNTVG------ 582

Query: 1621 KENGKCHCKENHYKPEGTAECL---PCQCYAAGSENSSCEAATG--QCHCRPG 1668
              +  C C +  Y+ +G  +C+    C   +      +C  + G  +C CRPG
Sbjct: 583  --SFSCSCHQG-YRLKGKHQCVDVDECSDNSLNRCQQTCNNSIGSFKCTCRPG 632



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 7/99 (7%)

Query: 1528 CVTSWDSSTCTCEAG---RVGPQCVSACELGPCGAARCVP--DQTPKGYSCACEPGYTLT 1582
            C  +  S +C+C  G   +   QCV   E       RC    + +   + C C PGY L 
Sbjct: 577  CTNTVGSFSCSCHQGYRLKGKHQCVDVDECSDNSLNRCQQTCNNSIGSFKCTCRPGYHLA 636

Query: 1583 TSGCIESGKEECPGGWWGGSACGPCACDVTRGYHP-HCN 1620
              G     KE+ P G              T G+ P H N
Sbjct: 637  IDG-FSCTKEKAPPGCGIALEADLANLAATPGWQPAHAN 674


>SB_14925| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 367

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 10/72 (13%)

Query: 1517 CMLSICPPYSKCV--TSWDSSTCTCEAGRVGPQC---VSACELG--PCG-AARCVPDQTP 1568
            C  S CP  + CV   + D+ TC C +G  G  C   V  C  G  PC  +A C    T 
Sbjct: 63   CSSSPCPVNTTCVPGPTQDTHTCACPSGYTGVDCENDVDECSDGQSPCHVSANC--SNTL 120

Query: 1569 KGYSCACEPGYT 1580
              ++C C+ G+T
Sbjct: 121  GSFTCTCKDGFT 132



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 1314 RSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDC 1348
            ++ CSS+PC     C      DT+ C C  G+TG DC
Sbjct: 60   KNGCSSSPCPVNTTCVPGPTQDTHTCACPSGYTGVDC 96



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 46/191 (24%), Positives = 72/191 (37%), Gaps = 33/191 (17%)

Query: 1550 SACELGPCGA-ARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA 1608
            + C   PC     CVP  T   ++CAC  GY  T   C E+  +EC     G S C   A
Sbjct: 61   NGCSSSPCPVNTTCVPGPTQDTHTCACPSGY--TGVDC-ENDVDECSD---GQSPCHVSA 114

Query: 1609 -CDVTRGYHPHCNKENGKCHCKENHYKPEGTA-----ECL-PCQCYAAGSENSSCEAATG 1661
             C  T G        +  C CK+  +  +G       ECL P  C+     N++C    G
Sbjct: 115  NCSNTLG--------SFTCTCKDG-FTGDGLTCKDVNECLRPNACHV----NATCTNTIG 161

Query: 1662 QCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCP 1721
              +C    +        + ++ +   + C+ ++   P S   G+++     G   +  C 
Sbjct: 162  SYNCSCQTLHH-----GDGHSCLLKGTSCQEIHSRFPHSL-DGMFYIVGNHGYPYLAHCD 215

Query: 1722 PGSSGRATRTC 1732
              S G     C
Sbjct: 216  MTSFGGGWTMC 226



 Score = 35.1 bits (77), Expect = 0.82
 Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 1310 CPEKRSRCSS--APCYNGAECSDLWDTYICDCKEGHTG 1345
            C      CS   +PC+  A CS+   ++ C CK+G TG
Sbjct: 96   CENDVDECSDGQSPCHVSANCSNTLGSFTCTCKDGFTG 133



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 4/37 (10%)

Query: 1043 TCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079
            TC CP G+TGV+CE  + + S   DG  S C   + C
Sbjct: 84   TCACPSGYTGVDCENDVDECS---DGQ-SPCHVSANC 116


>SB_3454| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 123

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 14/32 (43%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +PC N   C ++ D+Y C C  G  GKDC
Sbjct: 11   CYPSPCKNAGTCVEVGDSYQCSCHVGWIGKDC 42



 Score = 36.3 bits (80), Expect = 0.35
 Identities = 14/33 (42%), Positives = 16/33 (48%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDCADSTG 1353
            PC NG  CS+   TY C+C  G  G  C    G
Sbjct: 53   PCQNGGTCSESLGTYRCNCMSGWQGLSCEVGCG 85



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 1511 CQSRADCM-LSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPK 1569
            C + + C+ ++ C     C  S  +  C C +G  G     +CE+G CG+  C P+    
Sbjct: 42   CGTESKCLPINPCQNGGTCSESLGTYRCNCMSGWQG----LSCEVG-CGS--CHPNAYCM 94

Query: 1570 GYSCACEPGYTLTTSGCIESGKEE 1593
               C C PGY      C  +G E+
Sbjct: 95   MDKCVCNPGYIGDGITCDVTGHED 118



 Score = 33.5 bits (73), Expect = 2.5
 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 6/67 (8%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC--VSAC-ELGPC-GAARCVPDQTPKGYS 1572
            C  S C     CV   DS  C+C  G +G  C   S C  + PC     C   ++   Y 
Sbjct: 11   CYPSPCKNAGTCVEVGDSYQCSCHVGWIGKDCGTESKCLPINPCQNGGTC--SESLGTYR 68

Query: 1573 CACEPGY 1579
            C C  G+
Sbjct: 69   CNCMSGW 75


>SB_48850| Best HMM Match : EGF_CA (HMM E-Value=2.1e-27)
          Length = 83

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 7/78 (8%)

Query: 1516 DCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQC--VSACELGPCGAARCVPDQTPK 1569
            +C L+I  CP    CV +  S TC C+ G   V   C  +  C LG              
Sbjct: 4    ECKLNISTCPANRYCVNNDGSYTCKCKPGYTLVNNTCEDIDECALGVANCPASADCFNYD 63

Query: 1570 G-YSCACEPGYTLTTSGC 1586
            G Y+C C+ GYTL    C
Sbjct: 64   GSYTCRCKRGYTLVNKTC 81



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 10/75 (13%)

Query: 1549 VSACELG--PCGAAR-CVPDQTPKGYSCACEPGYTLTTSGCIE-----SGKEECPGGWWG 1600
            +  C+L    C A R CV +     Y+C C+PGYTL  + C +      G   CP     
Sbjct: 2    IDECKLNISTCPANRYCVNNDG--SYTCKCKPGYTLVNNTCEDIDECALGVANCPASADC 59

Query: 1601 GSACGPCACDVTRGY 1615
             +  G   C   RGY
Sbjct: 60   FNYDGSYTCRCKRGY 74


>SB_40335| Best HMM Match : EGF (HMM E-Value=2.5e-09)
          Length = 309

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 1315 SRCSSAPCYNGAECSDLWD-TYICDCKEGHTGKDC 1348
            S C + PC+NGA C    D +Y C C  G TGK C
Sbjct: 151  SACKNNPCHNGATCHQENDESYKCACASGFTGKHC 185


>SB_20425| Best HMM Match : EGF_CA (HMM E-Value=1.2e-20)
          Length = 144

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 10/74 (13%)

Query: 1037 YPVTSFTCQCPEGFTGVN--CETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSI 1094
            Y       +C +GF  VN  CE I      E  GDG +C+ G+ CV  R GG  CQ    
Sbjct: 25   YRCEGVAIRCQQGFEPVNGKCEDIN-----ECTGDGKVCQPGTVCV-NRVGGFTCQPMPC 78

Query: 1095 DAAY--TTAVCELR 1106
             + Y     VCE +
Sbjct: 79   PSGYIRVNGVCECK 92


>SB_15408| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 779

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 50/183 (27%), Positives = 63/183 (34%), Gaps = 31/183 (16%)

Query: 1527 KCVTSWDSSTCTCEAGRVGPQCVSACE--------LGPCGAARCVPDQTPKGYSCACEPG 1578
            KCV +  S  C C AGR      + CE           C   RCV   T  GY C C  G
Sbjct: 104  KCVNTVGSFKCDCGAGRTMDPVTNKCEDVDECKTITNICANGRCV--NTNGGYRCECPRG 161

Query: 1579 YTLTTSG--CIESGKEECPGGWWGGSACGPCACDVTR--GYHPHCNKE--NGKCHCKENH 1632
            + L+  G  CI +         W  +    C   + R       C K   NG CH   + 
Sbjct: 162  FALSQDGMYCIAT---------WALATSLMCLLRMLRKDSTPGRCYKRIVNGYCHMGSSL 212

Query: 1633 YKPEGTAECLPCQCYAAGSENSSCEA-ATGQCHCRPGVIGRA----CDACANAYAEVTPN 1687
               +    C   Q  A G +   C A  T + +   GV+  A     D C    A   PN
Sbjct: 213  STTQAACCCSMMQSKAWGPDCKRCPAPGTDEYNKLCGVVPSAKPPEVDEC-RMDANACPN 271

Query: 1688 SGC 1690
              C
Sbjct: 272  GRC 274



 Score = 33.1 bits (72), Expect = 3.3
 Identities = 22/81 (27%), Positives = 29/81 (35%), Gaps = 11/81 (13%)

Query: 1546 PQCVSACEL--GPCGAARCVPDQTPKGYSCACEPGYTLTT---SGCIESGKEECPGGWWG 1600
            P  V  C +    C   RC+    P G+ C C  GY L T   + C++  + E       
Sbjct: 256  PPEVDECRMDANACPNGRCI--DMPSGFRCVCNDGYILPTGRDNKCVDKNECEADSTLCT 313

Query: 1601 GSAC----GPCACDVTRGYHP 1617
               C    G   C    GY P
Sbjct: 314  NGRCVNTEGSYKCTCNNGYKP 334


>SB_7767| Best HMM Match : Laminin_EGF (HMM E-Value=3.4e-05)
          Length = 52

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 6/51 (11%)

Query: 1644 CQCYAAGS---ENSSCEAATGQCHCRPGVIGRACDAC-ANAYAEVTPNSGC 1690
            C C    +    ++ C A TGQC C+  + GR CD C  NAY   T + GC
Sbjct: 2    CDCVLPNTLYGNSTVCNATTGQCTCKEKISGRTCDRCHENAYN--TSDRGC 50


>SB_3977| Best HMM Match : EGF (HMM E-Value=1.8e-09)
          Length = 108

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 14/37 (37%), Positives = 19/37 (51%)

Query: 1312 EKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            E   +C + PC NG  C    + Y C C EG+ G +C
Sbjct: 17   EDIDKCHAMPCMNGGTCIATLNNYRCQCPEGYRGSNC 53



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 12/23 (52%), Positives = 16/23 (69%)

Query: 1036 IYPVTSFTCQCPEGFTGVNCETI 1058
            I  + ++ CQCPEG+ G NCE I
Sbjct: 34   IATLNNYRCQCPEGYRGSNCEGI 56


>SB_3108| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 631

 Score = 39.9 bits (89), Expect = 0.029
 Identities = 50/187 (26%), Positives = 62/187 (33%), Gaps = 34/187 (18%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574
            C   +KC     S  CTC  G  G    C  +  C  G   C   A+C  + T   Y C 
Sbjct: 330  CDKNAKCNNIIGSYHCTCNPGFSGDGRNCTDIDECVTGDHTCDKNAKC--NNTIGSYHCT 387

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYK 1634
            C PG++     C +   +EC          G   CD     +  CN   G  HC  N   
Sbjct: 388  CNPGFSGDGRNCTDI--DEC--------VTGDHTCD----KNAKCNNTIGSYHCMCNPGF 433

Query: 1635 PEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC---DACANAYAE 1683
                 EC        G     +N+ C    G   C C PG    GR C   D C      
Sbjct: 434  SGDGRECTDIDECVTGDHTCDKNAKCNNIIGSYHCTCNPGFSGDGRNCTDIDECVTGDHT 493

Query: 1684 VTPNSGC 1690
               N+ C
Sbjct: 494  CDKNAKC 500



 Score = 38.7 bits (86), Expect = 0.066
 Identities = 48/198 (24%), Positives = 64/198 (32%), Gaps = 32/198 (16%)

Query: 1511 CQSRADCMLS--ICPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGPCGAAR-CV 1563
            C    +C      C   +KC  +  S  C C  G  G   +C  +  C  G     +  +
Sbjct: 153  CSETDECSAGNHTCGKNAKCNNTIGSYHCMCNPGFSGDGRECTDIDECVTGDHTCDKNAI 212

Query: 1564 PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKEN 1623
             + T   Y C C PG++     C +   +EC        A G   CD     +  CN   
Sbjct: 213  CNNTIGSYHCRCNPGFSGDGRNCTDI--DEC--------ATGDHICD----KNAKCNNTI 258

Query: 1624 GKCHCKENHYKPEGTAECLPCQCYAAG----SENSSCEAATG--QCHCRPGVI--GRAC- 1674
            G  HC  N         C        G     +N+ C    G   C C PG    GR C 
Sbjct: 259  GSYHCMCNPGFSGDGRNCTDIDECVTGDHTCDKNAKCNNTIGSYHCMCNPGFSGDGRECT 318

Query: 1675 --DACANAYAEVTPNSGC 1690
              D C         N+ C
Sbjct: 319  DIDECVTGDHTCDKNAKC 336



 Score = 35.5 bits (78), Expect = 0.62
 Identities = 34/108 (31%), Positives = 43/108 (39%), Gaps = 16/108 (14%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QC--VSACELGP--CGA-ARCVPDQTPKGYSCA 1574
            C   +KC  +  S  C C  G  G    C  +  C  G   C   A+C  D T   Y C 
Sbjct: 494  CDKNAKCNNTIGSYHCMCNPGFSGDGRNCTDIDECVTGDHTCDKNAKC--DNTIGSYHCT 551

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDVTRG-YHPHCN 1620
            C PG++     C ++  +EC     G   C   A C  T G YH  CN
Sbjct: 552  CNPGFSGNGRECTDT--DECV---TGDHTCDKNARCGNTIGSYHCTCN 594



 Score = 31.9 bits (69), Expect = 7.6
 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 11/83 (13%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QCVSA--CELGP--CGA-ARCVPDQTPKGYSCA 1574
            C   +KC  +  S  CTC  G  G   +C     C  G   C   ARC    T   Y C 
Sbjct: 535  CDKNAKCDNTIGSYHCTCNPGFSGNGRECTDTDECVTGDHTCDKNARC--GNTIGSYHCT 592

Query: 1575 CEPGYTLTTSGCIESGKEECPGG 1597
            C PG++     C +   +EC  G
Sbjct: 593  CNPGFSGNGRECTDI--DECVTG 613


>SB_7933| Best HMM Match : GCC2_GCC3 (HMM E-Value=1.4e-18)
          Length = 1023

 Score = 39.5 bits (88), Expect = 0.038
 Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 37/232 (15%)

Query: 1520 SICPPYSKCVTSWDSSTCTC-EAGRVGPQCVSACELGP----CGAARCVPDQTPKGYS-- 1572
            S CP   +C     +S CT  +   VG    S C+  P    C     +P   P G    
Sbjct: 270  SACPAGYECSVG-TASLCTAGQYSTVGSP--SGCQTCPSNKVCADPSQLPQNCPAGEEVA 326

Query: 1573 ---CACEPGYTLTTSGCIESGKEECPGGWW---GGSACGPCACDVTRGYHPHCNKENGKC 1626
                AC+P      S   E+  + C  G++   G S+C PC+       H   N+     
Sbjct: 327  ASKAACQPCAAGEYSNTGEAC-QPCTTGYFSLGGASSCTPCSIG-----HQCSNQTIAPV 380

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVI--GRACDACANAYAEV 1684
             C    Y P G A C  C+   AG+       A+    C  G    G+   +C    A  
Sbjct: 381  RCSPGEYAPAGQANCTACE---AGTYCPDVPLASPYM-CTNGTYSNGQRQTSCQTCQAGY 436

Query: 1685 TPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETK 1736
               SG +        +   G +   +K G +T T+CP G S  A+++ D  K
Sbjct: 437  RCGSGAK-----SETACGDGTY---SKEGSDTCTECPAGHS-CASKSADPVK 479



 Score = 32.7 bits (71), Expect = 4.4
 Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 14/176 (7%)

Query: 1526 SKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQTPKGYSCACEPGYTLTT-- 1583
            S+CV      +C   +    PQ  +A    P G   C P Q+ K       PG T  T  
Sbjct: 787  SRCVECPAGQSCMSGSSPTTPQDCAAGTYSPPGFGTCKPCQSGKKLVNPVNPGATYCTPC 846

Query: 1584 ---SGC--IESGKEECPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCHCKENHYKPEG 1637
               S C    S +  C  G +       C  D   GY  P  + +  +C           
Sbjct: 847  PAGSSCPTPSSPRVPCTAGTYSLEGVAACV-DCPVGYMCPSTSWQPLRCPFGTTTLGASK 905

Query: 1638 TAECLPCQC-YAAGS-ENSSCEAATGQCHCRPGVIGRAC---DACANAYAEVTPNS 1688
               C  C   YA  + EN+      G+   + G     C    ACA     VTP S
Sbjct: 906  ALNCTDCPAGYACTTPENNITACNQGEYSLKRGARCITCPAGSACAQTDLHVTPVS 961


>SB_58992| Best HMM Match : VWA (HMM E-Value=2.4e-15)
          Length = 303

 Score = 39.5 bits (88), Expect = 0.038
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 1286 SDFYIDHKFID-LNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHT 1344
            S F I  K I+ L SYV  +    G     + CSS+PC NG  C    ++Y C C+  + 
Sbjct: 139  SQFIIADKNINVLGSYV--DRLRNGIGGVTNPCSSSPCLNGGSCVKTSNSYNCTCRAAYN 196

Query: 1345 GKDC 1348
            G  C
Sbjct: 197  GDRC 200


>SB_43977| Best HMM Match : VWA (HMM E-Value=4.9e-13)
          Length = 227

 Score = 39.5 bits (88), Expect = 0.038
 Identities = 14/32 (43%), Positives = 18/32 (56%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S+PC NG  CS L   Y+C C +   G  C
Sbjct: 5    CASSPCKNGGTCSKLSSGYVCKCTKQFNGSRC 36


>SB_32754| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 5659

 Score = 39.5 bits (88), Expect = 0.038
 Identities = 53/207 (25%), Positives = 79/207 (38%), Gaps = 35/207 (16%)

Query: 1503 VRENVRDG--CQSRADCML--SICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGP-- 1556
            +R  + DG  C    +C L  + C   ++C+ S  S +C C+ G  G    +  +LGP  
Sbjct: 529  LRGYIGDGKTCIDFDECKLPKNDCDVNAECINSIGSYSCICKPGFTG-NGKTCTDLGPVK 587

Query: 1557 ----CGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCA-CDV 1611
                CG      D   K ++C C+ GY +    C    K EC G       C P A C  
Sbjct: 588  CDPTCGDLETCVDIKGK-FTCVCKNGYQIVDGEC--KDKNECVG---SDLLCDPNALCTN 641

Query: 1612 TRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSE----NSSCEAATGQ--CHC 1665
            T G +         C CK   ++ +G   C      + GS     N+ C    G   C C
Sbjct: 642  TPGSY--------LCRCKSG-FQGDGKT-CADIDECSDGSHDCHVNAICTNVPGTFLCRC 691

Query: 1666 RPGVIGRACDACANAYAEVTPNSGCEV 1692
              G +G     CA+        + C++
Sbjct: 692  INGFLGDG-KLCADINECFEGTANCDI 717



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 47/189 (24%), Positives = 68/189 (35%), Gaps = 39/189 (20%)

Query: 1522 CPPYSKCVTSWDSSTCTCEAGRVGP--QCVS--ACEL--GPCGA-ARCVPDQTPKGYSCA 1574
            C   + C  +  +  C C  G +G    C+    C+L    C   A C+   +   YSC 
Sbjct: 511  CSVNALCTNTDGTFICRCLRGYIGDGKTCIDFDECKLPKNDCDVNAECI--NSIGSYSCI 568

Query: 1575 CEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK--CHCKENH 1632
            C+PG+T     C +                GP  CD T G    C    GK  C CK  +
Sbjct: 569  CKPGFTGNGKTCTD---------------LGPVKCDPTCGDLETCVDIKGKFTCVCKNGY 613

Query: 1633 YKPEGTA----ECLPCQCYAAGSENSSCEAATGQ--CHCRPGV--IGRAC---DACANAY 1681
               +G      EC+          N+ C    G   C C+ G    G+ C   D C++  
Sbjct: 614  QIVDGECKDKNECVGSDLLC--DPNALCTNTPGSYLCRCKSGFQGDGKTCADIDECSDGS 671

Query: 1682 AEVTPNSGC 1690
             +   N+ C
Sbjct: 672  HDCHVNAIC 680



 Score = 35.9 bits (79), Expect = 0.47
 Identities = 47/179 (26%), Positives = 70/179 (39%), Gaps = 33/179 (18%)

Query: 1507 VRDG--CQSRADCMLSI--CPPYSKCVTSWDSSTCTCEAG--RVGPQCVSACELGPCGAA 1560
            V DG  C  + +C+     C   + C+ S  S +C C  G    G QC    E       
Sbjct: 204  VGDGKTCVDKDECVEEDHDCAKSADCINSVGSYSCQCRPGFEGDGKQCKDVDECASVLHN 263

Query: 1561 RCVPD----QTPKGYSCACEPGYTLTTSGCIE-----SGKEECPGGWWGGSACGPCACDV 1611
            +C P+     +   Y C C+ GYT     C +     +  ++C       +  G   C  
Sbjct: 264  KCDPNALCTNSVGSYVCRCKKGYTGDGITCKDIDECTNKTDDCDANALCTNVLGSFVCRC 323

Query: 1612 TRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSC--EAATGQCHCRPG 1668
             +G+     + NGK  C      P+   EC P    A G+ NS C  +AA  +C C+ G
Sbjct: 324  LKGF-----EGNGKT-C-----IPKLQTECNP----ACGN-NSECKMQAAGAECVCKMG 366



 Score = 33.9 bits (74), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 2/26 (7%)

Query: 1039 VTSFTCQCPEGFT--GVNCETILTKA 1062
            V S+ CQC EG+T  G NC+ I+TK+
Sbjct: 725  VGSYNCQCMEGYTGDGKNCQAIITKS 750


>SB_27540| Best HMM Match : Laminin_EGF (HMM E-Value=5.4e-12)
          Length = 674

 Score = 39.5 bits (88), Expect = 0.038
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 14/91 (15%)

Query: 1626 CH-CKENHYKPEGTA-----ECLPCQCYAAGSE--NSSC-EAATGQCHCRPGVIGRACDA 1676
            CH C+++ ++  G +      C PCQC   G E   +SC   ++G C C+  V    C  
Sbjct: 276  CHVCRDDFFREPGKSLSAVDVCSPCQCTGPGVETGKTSCARVSSGNCTCKKYVREPTCGQ 335

Query: 1677 CANAYAEVTPNS--GCEVVYDGC-PRSFAGG 1704
            C   Y  ++ ++  GC+     C P+   GG
Sbjct: 336  CMKGYFNLSSSNPEGCQAC--NCNPKGTLGG 364


>SB_7814| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 61

 Score = 39.5 bits (88), Expect = 0.038
 Identities = 25/58 (43%), Positives = 32/58 (55%), Gaps = 3/58 (5%)

Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSY 223
           D PV A + A+D D+GAN  + Y+I  G     F I DS SG +SL   L Y Q  +Y
Sbjct: 5   DTPV-ATVIASDKDIGANRRLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNY 60


>SB_34004| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 235

 Score = 39.1 bits (87), Expect = 0.050
 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 21/106 (19%)

Query: 1001 ICVHEPCLNFE--ECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETI 1058
            IC    C N +  EC+T     N +  +N++            +TC+C  GFTG NCE  
Sbjct: 116  ICSLRYCGNGDVNECVTKKPCKNGASCINNEG----------GYTCKCTSGFTGKNCEND 165

Query: 1059 LTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
            + +   +       C++G+ C+   +GG  C+ C+  + +T   CE
Sbjct: 166  VNECVTK-----KPCKNGASCI-NNKGGYTCK-CT--SGFTGKNCE 202



 Score = 38.3 bits (85), Expect = 0.088
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)

Query: 1310 CPEKRSRC-SSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C    + C +  PC NGA C +    Y C C  G TGK+C
Sbjct: 162  CENDVNECVTKKPCKNGASCINNKGGYTCKCTSGFTGKNC 201



 Score = 37.5 bits (83), Expect = 0.15
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 8/89 (8%)

Query: 1498 LNRPTVRENVRDGCQSRADCMLSI-CPPYSKCVTSWDSSTCTCEAGRVGPQC---VSAC- 1552
            L RPT+      G     +C+    C   + C+ +    TC C +G  G  C   V+ C 
Sbjct: 111  LQRPTICSLRYCGNGDVNECVTKKPCKNGASCINNEGGYTCKCTSGFTGKNCENDVNECV 170

Query: 1553 ELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
               PC   A C+ ++   GY+C C  G+T
Sbjct: 171  TKKPCKNGASCINNK--GGYTCKCTSGFT 197



 Score = 37.1 bits (82), Expect = 0.20
 Identities = 14/28 (50%), Positives = 16/28 (57%)

Query: 1321 PCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            PC NGA C +    Y C C  G TGK+C
Sbjct: 135  PCKNGASCINNEGGYTCKCTSGFTGKNC 162


>SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40)
          Length = 1042

 Score = 39.1 bits (87), Expect = 0.050
 Identities = 36/101 (35%), Positives = 43/101 (42%), Gaps = 15/101 (14%)

Query: 1528 CVTSWDSSTCTCEAGRV--GPQCVSACELGPCGAA-RCVPDQTPKG----YSCACEPGYT 1580
            CV +  S  C C AG    G QC    E   CGA+ RC  + T       Y CAC+PG+T
Sbjct: 735  CVNTPGSYACVCPAGYTVSGYQCNDVNE---CGASDRCHVNATCTNTIGSYICACKPGFT 791

Query: 1581 LTTSGCIESGKEECPGGWWGGSACGPCACDVTRG-YHPHCN 1620
                 C +   +EC  G    S      CD T G Y   CN
Sbjct: 792  GNGFNCTD--VDECTMG--THSCHANAQCDNTIGSYTCRCN 828



 Score = 32.3 bits (70), Expect = 5.8
 Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 2/43 (4%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGK--DCAD 1350
            C +     +S  C+  A C++   +YIC CK G TG   +C D
Sbjct: 757  CNDVNECGASDRCHVNATCTNTIGSYICACKPGFTGNGFNCTD 799


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.317    0.134    0.404 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,751,511
Number of Sequences: 59808
Number of extensions: 4279957
Number of successful extensions: 19918
Number of sequences better than 10.0: 426
Number of HSP's better than 10.0 without gapping: 242
Number of HSP's successfully gapped in prelim test: 184
Number of HSP's that attempted gapping in prelim test: 10054
Number of HSP's gapped (non-prelim): 5140
length of query: 2796
length of database: 16,821,457
effective HSP length: 95
effective length of query: 2701
effective length of database: 11,139,697
effective search space: 30088321597
effective search space used: 30088321597
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)

- SilkBase 1999-2023 -